locus-tag	class	description
BBTM_00008	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BBTM_00009	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BBTM_00011	ENOG4105VEQ	Cold shock protein
BBTM_00018	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBTM_00020	ENOG4105BZU	Histidine kinase
BBTM_00021	ENOG4105VEQ	Cold shock protein
BBTM_00027	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BBTM_00033	ENOG4105C99	atpase involved in dna repair
BBTM_00043	ENOG4105CDA	abc transporter atp-binding protein
BBTM_00044	ENOG4108HW3	(ABC) transporter
BBTM_00045	ENOG4105CT1	(ABC) transporter
BBTM_00047	ENOG4108Q1T	ABC transporter
BBTM_00048	ENOG4105DRP	amino acid AbC transporter
BBTM_00049	ENOG4105CSR	polyphosphate kinase 2
BBTM_00056	ENOG4105BZ1	(ABC) transporter
BBTM_00063	ENOG4108JJB	ABC transporter
BBTM_00082	ENOG4105C5F	glutamine synthetase
BBTM_00086	ENOG4107QN2	dihydrolipoyl dehydrogenase
BBTM_00094	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BBTM_00100	ENOG4105DJZ	UPF0182 protein
BBTM_00102	ENOG4107RZX	Teichoic acid biosynthesis protein
BBTM_00106	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BBTM_00111	ENOG4105EY8	ABC transporter
BBTM_00113	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BBTM_00118	ENOG4105CRQ	synthase (Component I)
BBTM_00119	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
BBTM_00130	ENOG4105EJQ	L-serine dehydratase
BBTM_00132	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BBTM_00133	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BBTM_00135	ENOG4108UT2	hemolysin iii
BBTM_00138	ENOG4105KRM	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
BBTM_00139	ENOG4105EC2	ftsk spoIIIe
BBTM_00140	ENOG4108KGH	TRANSCRIPTIONal
BBTM_00141	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
BBTM_00150	ENOG4105MJ2	Competence protein
BBTM_00152	ENOG4105EB3	Histidine kinase
BBTM_00153	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBTM_00157	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BBTM_00161	ENOG4105CC5	ABC transporter
BBTM_00163	ENOG4105DIK	(ABC) transporter
BBTM_00168	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BBTM_00170	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BBTM_00172	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BBTM_00176	ENOG4105CA9	Pyruvate kinase
BBTM_00178	ENOG4108YZ4	nudix hydrolase
BBTM_00184	ENOG4105EGD	dinuclear metal center protein, YbgI family
BBTM_00185	ENOG41087AY	ADP-Ribose pyrophosphatase
BBTM_00188	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBTM_00190	ENOG4107UIE	peptidase
BBTM_00194	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BBTM_00196	ENOG4105C6K	Malic enzyme
BBTM_00203	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BBTM_00207	ENOG4105CJ3	phosphate transporter
BBTM_00209	ENOG4105WH1	Two component transcriptional regulator luxr family
BBTM_00211	ENOG4105BZU	Histidine kinase
BBTM_00215	ENOG4105CJ1	ABC, transporter
BBTM_00219	ENOG4105CB5	ATP-dependent DNA helicase recG
BBTM_00224	ENOG4105MP0	transposase
BBTM_00231	ENOG4108RWI	nicotinamidase
BBTM_00234	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BBTM_00244	ENOG4105EXC	Acyl-transferase
BBTM_00249	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BBTM_00254	ENOG4105EXC	Acyl-transferase
BBTM_00258	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BBTM_00264	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BBTM_00266	ENOG4105D49	3-dehydroquinate synthase
BBTM_00267	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BBTM_00273	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BBTM_00275	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BBTM_00278	ENOG4105JRK	feS assembly protein SufD
BBTM_00280	ENOG4105C3K	feS assembly ATPase SufC
BBTM_00286	ENOG4105VG1	fes assembly suf system protein
BBTM_00288	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BBTM_00292	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BBTM_00305	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BBTM_00306	ENOG4105W8H	transhydrogenase (subunit alpha
BBTM_00308	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BBTM_00314	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BBTM_00319	ENOG4105EN6	Membrane
BBTM_00320	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BBTM_00326	ENOG4105CHM	Aminotransferase
BBTM_00332	ENOG4105CBC	glutamate synthase
BBTM_00337	ENOG4107QPH	glycogen) synthase
BBTM_00339	ENOG4105DKW	ABC transporter
BBTM_00341	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BBTM_00347	ENOG4105F9F	transposase
BBTM_00348	ENOG4105C0D	helicase
BBTM_00352	ENOG4105C4R	Atp-dependent dna helicase
BBTM_00354	ENOG4105D5G	Transposase
BBTM_00356	ENOG4105D5G	Transposase
BBTM_00357	ENOG4105D5G	Transposase
BBTM_00359	ENOG4105D5G	Transposase
BBTM_00363	ENOG4105FR1	rard protein
BBTM_00365	ENOG4107XM9	(LipO)protein
BBTM_00367	ENOG4105M4E	phosphohistidine phosphatase, SixA
BBTM_00369	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BBTM_00371	ENOG4105SYT	Methylenetetrahydrofolate reductase
BBTM_00376	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
BBTM_00377	ENOG4105CD3	dihydroorotase
BBTM_00379	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
BBTM_00380	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
BBTM_00381	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BBTM_00382	ENOG4107T14	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BBTM_00385	ENOG4105CPQ	Dehydrogenase
BBTM_00391	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BBTM_00397	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
BBTM_00403	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
BBTM_00406	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
BBTM_00409	ENOG4108RFG	Tetr family transcriptional regulator
BBTM_00412	ENOG4107R11	Transcriptional regulator
BBTM_00428	ENOG4105Q70	
BBTM_00431	ENOG4108Z5K	methylglyoxal synthase
BBTM_00454	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BBTM_00456	ENOG4105DJV	ribulose-phosphate 3-epimerase
BBTM_00460	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BBTM_00461	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BBTM_00463	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BBTM_00465	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BBTM_00473	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BBTM_00476	ENOG4105VIE	preprotein translocase, subunit YajC
BBTM_00477	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BBTM_00479	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BBTM_00481	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BBTM_00486	ENOG4105E2D	ec 3.2.1.52
BBTM_00491	ENOG4107QJT	sodium dicarboxylate symporter
BBTM_00499	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BBTM_00500	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BBTM_00502	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BBTM_00504	ENOG4105XPP	Protein of unknown function (DUF1275)
BBTM_00506	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
BBTM_00520	ENOG4105CIE	May be required for sporulation (By similarity)
BBTM_00521	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BBTM_00522	ENOG4105E2X	shikimate dehydrogenase
BBTM_00531	ENOG4105F44	Two component transcriptional regulator, winged helix family
BBTM_00533	ENOG4105D5G	Transposase
BBTM_00534	ENOG4106F60	Histidine kinase
BBTM_00535	ENOG4108UZE	carboxy-peptidase
BBTM_00538	ENOG4105C5H	ABC transporter
BBTM_00545	ENOG4105DKQ	ROK family
BBTM_00546	ENOG4105DKQ	ROK family
BBTM_00552	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BBTM_00560	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BBTM_00561	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BBTM_00566	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BBTM_00571	ENOG4105CE9	30S ribosomal protein S2
BBTM_00572	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BBTM_00575	ENOG4108IQE	Amp-dependent synthetase and ligase
BBTM_00581	ENOG4107QVP	Dehydrogenase
BBTM_00585	ENOG4108IQE	Amp-dependent synthetase and ligase
BBTM_00588	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BBTM_00590	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
BBTM_00592	ENOG4108097	ATP-binding protein
BBTM_00602	ENOG4105CT1	(ABC) transporter
BBTM_00603	ENOG4105D7N	magnesium and cobalt transport protein CorA
BBTM_00605	ENOG4105CVJ	phosphoglycerate mutase
BBTM_00613	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
BBTM_00614	ENOG4105K78	MarR family Transcriptional regulator
BBTM_00627	ENOG4108RAV	Conserved protein
BBTM_00642	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BBTM_00657	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
BBTM_00659	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BBTM_00660	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BBTM_00662	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BBTM_00664	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BBTM_00666	ENOG4105D98	threonine synthase
BBTM_00673	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
BBTM_00675	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BBTM_00678	ENOG4105CZN	Potassium uptake protein
BBTM_00680	ENOG4107ZYR	domain protein
BBTM_00687	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
BBTM_00691	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BBTM_00698	ENOG4105DZR	Type I site-specific deoxyribonuclease
BBTM_00700	ENOG4105D5G	Transposase
BBTM_00701	ENOG4105DZR	Type I site-specific deoxyribonuclease
BBTM_00708	ENOG4108FPN	Integrase
BBTM_00712	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
BBTM_00716	ENOG4105C8Y	Acetylornithine aminotransferase
BBTM_00718	ENOG4105CAS	nag kinase
BBTM_00719	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BBTM_00725	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BBTM_00727	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BBTM_00728	ENOG4108RWN	rrna methyltransferase
BBTM_00730	ENOG4105C19	ABC transporter
BBTM_00735	ENOG4105D5G	Transposase
BBTM_00738	ENOG4105C2W	permease
BBTM_00742	ENOG4107TGP	family UPF0324
BBTM_00745	ENOG4105DUM	transcriptional regulator, lysR family
BBTM_00757	ENOG4107YDN	peptide deformylase
BBTM_00762	ENOG4105D5G	Transposase
BBTM_00772	ENOG4108PBA	serine threonine protein kinase
BBTM_00782	ENOG4105DQ6	Transposase
BBTM_00791	ENOG4105C79	DNA protecting protein DprA
BBTM_00799	ENOG4105C3G	gtp-binding protein
BBTM_00800	ENOG4105CHM	Aminotransferase
BBTM_00801	ENOG4108UMI	ABC transporter, permease
BBTM_00802	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BBTM_00803	ENOG4105CPP	Dehydrogenase, E1 component
BBTM_00806	ENOG4107RUY	(E1 component), alpha subunit
BBTM_00808	ENOG4105D01	(LipO)protein
BBTM_00811	ENOG4105D44	asparaginase
BBTM_00813	ENOG4105II7	pyrroline-5-carboxylate reductase
BBTM_00816	ENOG4105BZU	Histidine kinase
BBTM_00818	ENOG4105WH1	Two component transcriptional regulator luxr family
BBTM_00821	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
BBTM_00822	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BBTM_00823	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BBTM_00830	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
BBTM_00831	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BBTM_00835	ENOG4105C0P	Mg chelatase subunit ChlI
BBTM_00842	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BBTM_00846	ENOG4105C87	Aminotransferase class I and II
BBTM_00847	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BBTM_00849	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BBTM_00850	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BBTM_00853	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BBTM_00860	ENOG4105C6N	Formate acetyltransferase
BBTM_00862	ENOG4105C4K	Nad synthetase
BBTM_00864	ENOG4105CH2	amidohydrolase
BBTM_00868	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BBTM_00869	ENOG410667J	hydrolase
BBTM_00876	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BBTM_00885	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBTM_00890	ENOG4107QRT	dEAD DEAH box helicase
BBTM_00891	ENOG4105VMP	Transcriptional regulator
BBTM_00894	ENOG4108IJ0	Aspartate ammonia-lyase
BBTM_00897	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBTM_00899	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBTM_00905	ENOG4105D9P	serine threonine protein kinase
BBTM_00908	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BBTM_00910	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BBTM_00913	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
BBTM_00917	ENOG4105KC9	Modulates RecA activity (By similarity)
BBTM_00918	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BBTM_00921	ENOG4105WBV	Transcriptional regulator
BBTM_00923	ENOG4105CEV	competence damage-inducible protein
BBTM_00925	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BBTM_00928	ENOG4107QZI	cell division protein FtsK
BBTM_00935	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BBTM_00943	ENOG4105HFZ	Membrane
BBTM_00948	ENOG4105WH1	Two component transcriptional regulator luxr family
BBTM_00951	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BBTM_00954	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BBTM_00965	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BBTM_00966	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BBTM_00974	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
BBTM_00975	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
BBTM_00979	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
BBTM_00991	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BBTM_00994	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BBTM_00995	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BBTM_01000	ENOG4107UZV	polysaccharide biosynthesis
BBTM_01001	ENOG4108SEA	Esterase
BBTM_01003	ENOG4105FF5	Membrane
BBTM_01009	ENOG4105KDC	50s ribosomal protein l28
BBTM_01010	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BBTM_01012	ENOG4108638	50S ribosomal protein L36
BBTM_01014	ENOG4108PJD	permease
BBTM_01018	ENOG41090R7	Ferric uptake
BBTM_01021	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BBTM_01022	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BBTM_01023	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BBTM_01025	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
BBTM_01027	ENOG4105CB5	ATP-dependent DNA helicase recG
BBTM_01028	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BBTM_01032	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BBTM_01033	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BBTM_01036	ENOG4105CUB	amino acid
BBTM_01041	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
BBTM_01045	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BBTM_01054	ENOG4108JQ7	(ABC) transporter
BBTM_01060	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
BBTM_01067	ENOG4105C4C	beta-galactosidase
BBTM_01068	ENOG4105DRS	transport system, permease
BBTM_01069	ENOG4105ETE	Transcriptional regulator (LacI family
BBTM_01075	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BBTM_01078	ENOG41082T9	Membrane
BBTM_01080	ENOG4105C26	Dehydrogenase
BBTM_01087	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BBTM_01088	ENOG4105BZW	Glycerate kinase
BBTM_01092	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BBTM_01093	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBTM_01096	ENOG4105CPC	Aldo Keto reductase
BBTM_01097	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BBTM_01101	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BBTM_01107	ENOG4105C9K	Endothelin-converting enzyme 1
BBTM_01111	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BBTM_01115	ENOG4107QUV	Domain protein
BBTM_01118	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BBTM_01121	ENOG4105CG3	alpha amylase, catalytic region
BBTM_01122	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BBTM_01124	ENOG4105ESV	Glycosyl transferase, family 4
BBTM_01125	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
BBTM_01128	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BBTM_01131	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BBTM_01132	ENOG4105VFB	Binds the 23S rRNA (By similarity)
BBTM_01135	ENOG4105CSC	Glucose uptake protein
BBTM_01137	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BBTM_01138	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BBTM_01143	ENOG4105D5G	Transposase
BBTM_01145	ENOG4105D5G	Transposase
BBTM_01152	ENOG4105C1J	atp-dependent rna helicase
BBTM_01159	ENOG4107WD8	ABC transporter, permease
BBTM_01167	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BBTM_01168	ENOG4105DKQ	ROK family
BBTM_01170	ENOG4105C5H	ABC transporter
BBTM_01171	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BBTM_01180	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
BBTM_01189	ENOG4105C29	acyl-CoA thioesterase
BBTM_01192	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBTM_01193	ENOG4105EEI	dihydropteroate synthase
BBTM_01197	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BBTM_01198	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BBTM_01207	ENOG4105K64	Glycosyl transferase, family 2
BBTM_01208	ENOG4105C0A	alcohol dehydrogenase
BBTM_01213	ENOG4105CMR	udp-glucose 4-epimerase
BBTM_01214	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BBTM_01219	ENOG4107RBJ	symporter
BBTM_01220	ENOG4105CNT	hydrolase family 2
BBTM_01221	ENOG4105CE4	GlcNAc 6-P deacetylase
BBTM_01223	ENOG4107KJX	Transcriptional regulator
BBTM_01224	ENOG4105US7	Histidine kinase
BBTM_01229	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BBTM_01233	ENOG4107WD8	ABC transporter, permease
BBTM_01235	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BBTM_01236	ENOG4105KMT	branched-chain amino acid
BBTM_01243	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BBTM_01244	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BBTM_01246	ENOG4108YV4	Universal stress protein
BBTM_01248	ENOG41068JE	domain protein
BBTM_01249	ENOG41068JE	domain protein
BBTM_01250	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BBTM_01255	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BBTM_01261	ENOG4105CRK	lysyL-tRNA synthetase
BBTM_01262	ENOG4105F27	Major Facilitator
BBTM_01270	ENOG4105WH1	Two component transcriptional regulator luxr family
BBTM_01273	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BBTM_01275	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
BBTM_01287	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BBTM_01296	ENOG4105C5Y	PTS System
BBTM_01303	ENOG4107QN2	dihydrolipoyl dehydrogenase
BBTM_01307	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BBTM_01312	ENOG4105DTN	riboflavin biosynthesis protein ribF
BBTM_01314	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BBTM_01315	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BBTM_01328	ENOG4105E2D	ec 3.2.1.52
BBTM_01332	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BBTM_01335	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBTM_01336	ENOG41067V7	50S ribosomal protein L36
BBTM_01337	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BBTM_01339	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BBTM_01341	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BBTM_01342	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BBTM_01348	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BBTM_01350	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBTM_01354	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BBTM_01356	ENOG41082SA	50s ribosomal protein l29
BBTM_01357	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BBTM_01360	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BBTM_01362	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBTM_01364	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BBTM_01370	ENOG4107FQX	Alpha-acetolactate decarboxylase
BBTM_01372	ENOG4108EKI	Dehydrogenase
BBTM_01384	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BBTM_01386	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BBTM_01388	ENOG4108Z4U	Ferredoxin
BBTM_01390	ENOG4107R4N	Cell wall formation (By similarity)
BBTM_01391	ENOG4105WDJ	50S ribosomal protein L33
BBTM_01393	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BBTM_01399	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
BBTM_01410	ENOG4108VZM	50s ribosomal protein L10
BBTM_01418	ENOG4105C7N	Xanthine uracil vitamin C permease
BBTM_01421	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BBTM_01422	ENOG4105E2Z	phosphate ABC transporter (Permease
BBTM_01427	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBTM_01430	ENOG4105BZU	Histidine kinase
BBTM_01432	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BBTM_01433	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BBTM_01439	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BBTM_01447	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
BBTM_01452	ENOG4105CFP	Peptidase U32
BBTM_01455	ENOG4105F9F	transposase
BBTM_01459	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BBTM_01461	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BBTM_01468	ENOG4108V0P	LemA family
BBTM_01469	ENOG4105FKQ	transcriptional regulator
BBTM_01473	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BBTM_01484	ENOG4105D8K	carboxyl transferase
BBTM_01486	ENOG4108JIK	carboxylase
BBTM_01489	ENOG4107ZYJ	bioY protein
BBTM_01491	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BBTM_01498	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BBTM_01500	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BBTM_01501	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BBTM_01502	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BBTM_01504	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BBTM_01505	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
BBTM_01508	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
BBTM_01509	ENOG4105CVG	Homoserine O-transsuccinylase
BBTM_01518	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
BBTM_01519	ENOG4105F0N	pyrophosphate phospho-hydrolase
BBTM_01520	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
BBTM_01524	ENOG4107NHD	transcriptional regulator
BBTM_01527	ENOG4105DEF	Extracellular solute-binding protein, family 5
BBTM_01529	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BBTM_01534	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
BBTM_01536	ENOG4105EW9	transcriptional regulator AsnC family
BBTM_01538	ENOG4105CHM	Aminotransferase
BBTM_01548	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BBTM_01550	ENOG4105CJ1	ABC, transporter
BBTM_01554	ENOG4105CGY	Dna recombination protein
BBTM_01556	ENOG4105VPX	protein, conserved in bacteria
BBTM_01563	ENOG4105DMS	mur ligase
BBTM_01564	ENOG4105CDU	Replicative dna helicase
BBTM_01568	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
BBTM_01574	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BBTM_01575	ENOG41067SE	Tetr family transcriptional regulator
BBTM_01577	ENOG4105K64	Glycosyl transferase, family 2
BBTM_01581	ENOG4105DZW	Dipeptidase
BBTM_01588	ENOG4105BZ1	(ABC) transporter
BBTM_01613	ENOG4105CS2	ec 3.2.1.21
BBTM_01616	ENOG4105CK1	PTS System
BBTM_01620	ENOG4105CMD	Transcriptional regulator, GntR family
BBTM_01624	ENOG4107R34	abc transporter permease protein
BBTM_01626	ENOG4107R34	abc transporter permease protein
BBTM_01628	ENOG4108SDV	Periplasmic Protein
BBTM_01629	ENOG4107SJW	iron permease, FTR1
BBTM_01633	ENOG4105C57	major facilitator superfamily
BBTM_01638	ENOG4105C4C	beta-galactosidase
BBTM_01649	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BBTM_01653	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BBTM_01655	ENOG4105C85	amino acid
BBTM_01662	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BBTM_01665	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BBTM_01668	ENOG4105CSH	Transporter
BBTM_01671	ENOG4107RK0	Sucrose phosphorylase
BBTM_01674	ENOG4108BVP	Protein CrcB homolog
BBTM_01681	ENOG4107RCW	fructose-bisphosphate aldolase
BBTM_01686	ENOG4105MU5	relaxase mobilization nuclease domain protein
BBTM_01699	ENOG4105D0M	Protease HtpX homolog
BBTM_01702	ENOG4105C59	p-type ATPase
BBTM_01704	ENOG4105C0H	protease
BBTM_01705	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BBTM_01709	ENOG4108I7Y	domain protein
BBTM_01716	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBTM_01727	ENOG4105M6F	mutator MutT protein
BBTM_01728	ENOG4105C1J	atp-dependent rna helicase
BBTM_01730	ENOG4105E0X	reductase
BBTM_01750	ENOG4105CJN	penicillin-binding protein
BBTM_01751	ENOG4107TPY	serine threonine protein kinase
BBTM_01752	ENOG4105D9P	serine threonine protein kinase
BBTM_01757	ENOG4105ZJT	Cell division protein CrgA
BBTM_01780	ENOG4105EY8	ABC transporter
BBTM_01783	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
BBTM_01785	ENOG4105D5G	Transposase
BBTM_01795	ENOG4105D5G	Transposase
BBTM_01797	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BBTM_01799	ENOG410838F	Glycosyl transferase family 2
BBTM_01802	ENOG4105D5G	Transposase
BBTM_01806	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BBTM_01809	ENOG4105DY9	regulatoR
BBTM_01811	ENOG4105C31	Tryptophanyl-tRNA synthetase
BBTM_01818	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BBTM_01824	ENOG4105D3R	alkyl hydroperoxide reductase
BBTM_01825	ENOG4108V9Q	carbonic anhydrase
BBTM_01832	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
BBTM_01839	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
BBTM_01840	ENOG41060NJ	transcriptional regulator
BBTM_01846	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
BBTM_01848	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BBTM_01853	ENOG4107R37	Glutamate dehydrogenase
BBTM_01860	ENOG4105ETE	Transcriptional regulator (LacI family
BBTM_01869	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBTM_01872	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBTM_01873	ENOG4105K7N	UPF0232 protein
BBTM_01874	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BBTM_01877	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BBTM_01881	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BBTM_01883	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BBTM_01885	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BBTM_01886	ENOG4107QJE	Chromosome Partitioning Protein
BBTM_01888	ENOG4105C3M	thioredoxin reductase
BBTM_01894	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BBTM_01896	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BBTM_01898	ENOG4106839	domain protein
BBTM_01906	ENOG4105F9F	transposase
BBTM_01915	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BBTM_01918	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBTM_01924	ENOG4105DHP	deoxycytidine triphosphate deaminase
BBTM_01926	ENOG4107SUZ	Sodium/hydrogen exchanger family
BBTM_01928	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BBTM_01930	ENOG4105C7B	Threonine dehydratase
BBTM_01931	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BBTM_01934	ENOG4108R0M	Aminoglycoside
BBTM_01937	ENOG4108DBC	nitroreductase
BBTM_01943	ENOG4105ETE	Transcriptional regulator (LacI family
BBTM_01946	ENOG4105CFG	Acts as a chaperone (By similarity)
BBTM_01948	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBTM_01953	ENOG4105KNI	merR family transcriptional Regulator
BBTM_01960	ENOG4105DQR	SNARE associated Golgi
BBTM_01965	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BBTM_01968	ENOG4105ETE	Transcriptional regulator (LacI family
BBTM_01971	ENOG4105F8V	Hydrolase, tatD family
BBTM_01973	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BBTM_01988	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BBTM_01993	ENOG4108MKI	Glycosyl transferase, family 2
BBTM_01995	ENOG4105D5G	Transposase
BBTM_02002	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BBTM_02003	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BBTM_02014	ENOG4105CBD	Diacylglycerol kinase
BBTM_02017	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BBTM_02018	ENOG4105CFH	Aspartokinase
BBTM_02020	ENOG4105CFH	Aspartokinase
BBTM_02024	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
BBTM_02036	ENOG4105BZ4	penicillin-binding protein
BBTM_02041	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BBTM_02046	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BBTM_02047	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BBTM_02050	ENOG4105C6E	dna polymerase iii
BBTM_02052	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BBTM_02053	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BBTM_02055	ENOG4107R3N	Filamentation induced by cAMP protein fic
BBTM_02059	ENOG4108C33	Resolvase
BBTM_02083	ENOG4105CPC	Aldo Keto reductase
BBTM_02090	ENOG4105BZ1	(ABC) transporter
BBTM_02093	ENOG4105BZ1	(ABC) transporter
BBTM_02101	ENOG4105DZW	Dipeptidase
BBTM_02102	ENOG4105CKU	formyltetrahydrofolate synthetase
BBTM_02112	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
BBTM_02116	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
BBTM_02137	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BBTM_02139	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BBTM_02144	ENOG4108RZE	Tetr family transcriptional regulator
BBTM_02146	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BBTM_02162	ENOG4105CHR	reductase
BBTM_02167	ENOG4105KME	endoribonuclease L-psp
BBTM_02169	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BBTM_02170	ENOG4105C75	arginyL-tRNA synthetase
BBTM_02173	ENOG4105CI1	PTS System
BBTM_02175	ENOG4105CI1	PTS System
BBTM_02176	ENOG4105D6E	homoserine dehydrogenase
BBTM_02177	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BBTM_02179	ENOG4108JW7	Maf-like protein
BBTM_02183	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BBTM_02189	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
BBTM_02195	ENOG4105C03	ribonuclease
BBTM_02196	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BBTM_02202	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBTM_02215	ENOG4105CPF	Cell wall formation (By similarity)
BBTM_02216	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BBTM_02218	ENOG4105ESP	cell wall surface anchor family protein
BBTM_02220	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BBTM_02228	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
BBTM_02229	ENOG4107YH6	single-stranded DNA-binding protein
BBTM_02231	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BBTM_02236	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BBTM_02240	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BBTM_02241	ENOG4105DFA	alanine racemase domain protein
BBTM_02243	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
BBTM_02251	ENOG4105ERH	Fumarylacetoacetate hydrolase
BBTM_02253	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BBTM_02259	ENOG4105CHM	Aminotransferase
BBTM_02266	ENOG4108IQE	Amp-dependent synthetase and ligase
BBTM_02267	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
BBTM_02275	ENOG4107SWG	transcriptional regulator MERR family
BBTM_02277	ENOG4105DEU	major facilitator superfamily
BBTM_02281	ENOG4105VB9	50S ribosomal protein l28
BBTM_02294	ENOG4106H78	methyltransferase
BBTM_02298	ENOG4107Y70	Heat shock protein
BBTM_02300	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BBTM_02301	ENOG41084QK	UPF0109 protein
BBTM_02303	ENOG4105K5M	30s ribosomal protein S16
BBTM_02305	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BBTM_02314	ENOG4105C8N	cysteinyl-tRNA synthetase
BBTM_02316	ENOG4105C8N	cysteinyl-tRNA synthetase
BBTM_02318	ENOG4105C5H	ABC transporter
BBTM_02325	ENOG41084BZ	50S ribosomal protein L32
BBTM_02326	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BBTM_02331	ENOG4108ZP8	Acetolactate synthase small subunit
BBTM_02334	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BBTM_02338	ENOG4107QP8	phosphohexose isomerase
BBTM_02349	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBTM_02350	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBTM_02358	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
BBTM_02360	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BBTM_02363	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BBTM_02364	ENOG4105ETE	Transcriptional regulator (LacI family
BBTM_02370	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
BBTM_02371	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BBTM_02375	ENOG4105ETE	Transcriptional regulator (LacI family
BBTM_02379	ENOG4105CV8	reductase
BBTM_02387	ENOG41080RH	Thioredoxin
BBTM_02393	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BBTM_02403	ENOG4105DF9	Lipoate-protein, ligase
BBTM_02404	ENOG4105IJJ	transcriptional regulator, crp fnr family
BBTM_02408	ENOG4105BZ4	penicillin-binding protein
BBTM_02409	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BBTM_02411	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BBTM_02412	ENOG4105MVE	transcriptional regulator
BBTM_02416	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BBTM_02419	ENOG4105CSH	Transporter
BBTM_02422	ENOG4105VUC	UPF0237 protein
BBTM_02424	ENOG4105CAG	UPF0210 protein
BBTM_02428	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BBTM_02434	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BBTM_02437	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BBTM_02450	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BBTM_02473	ENOG4105CN5	Metallo-Beta-Lactamase
BBTM_02478	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
BBTM_02481	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BBTM_02487	ENOG4105CHM	Aminotransferase
BBTM_02488	ENOG4107R33	ppx gppa phosphatase
BBTM_02490	ENOG4107R33	ppx gppa phosphatase
BBTM_02494	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
BBTM_02498	ENOG4105ETE	Transcriptional regulator (LacI family
BBTM_02501	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BBTM_02502	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BBTM_02504	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BBTM_02506	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
BBTM_02514	ENOG4105D7V	transposase
BBTM_02525	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
BBTM_02527	ENOG4105BZ1	(ABC) transporter
BBTM_02530	ENOG4105BZ1	(ABC) transporter
BBTM_02534	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BBTM_02538	ENOG4105DB7	PHP domain protein
BBTM_02547	ENOG41063PX	domain protein
BBTM_02553	ENOG4105D5G	Transposase
BBTM_02556	ENOG4105DWF	phosphomethylpyrimidine kinase
BBTM_02561	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BBTM_02563	ENOG4105CNT	hydrolase family 2
BBTM_02566	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
BBTM_02567	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
BBTM_02572	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BBTM_02573	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BBTM_02579	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BBTM_02583	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
BBTM_02586	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BBTM_02587	ENOG4105CAK	Cell division ATP-binding protein ftsE
BBTM_02590	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
BBTM_02592	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
BBTM_02594	ENOG4105D3G	Pseudouridine synthase
BBTM_02602	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BBTM_02605	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
BBTM_02606	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BBTM_02607	ENOG4108XI2	Domain of unknown function (DUF1963)
BBTM_02609	ENOG4108HKT	sucrose-6-phosphate hydrolase
BBTM_02610	ENOG4108HKT	sucrose-6-phosphate hydrolase
BBTM_02612	ENOG4105C0B	DNA polymerase III (alpha subunit)
BBTM_02617	ENOG4105CCI	Myosin-Cross-Reactive Antigen
BBTM_02619	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BBTM_02622	ENOG4105CV8	reductase
BBTM_02624	ENOG4105CV8	reductase
BBTM_02627	ENOG4105M0C	cytoplasmic protein
BBTM_02634	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BBTM_02636	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BBTM_02637	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BBTM_02640	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BBTM_02641	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BBTM_02653	ENOG4105CQ7	ATP-dependent helicase
BBTM_02654	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BBTM_02659	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BBTM_02663	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BBTM_02665	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BBTM_02667	ENOG4108JQ1	Dehydrogenase
BBTM_02670	ENOG4108V6E	Cell division protein mraZ
BBTM_02671	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BBTM_02674	ENOG4105CJN	penicillin-binding protein
BBTM_02682	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BBTM_02686	ENOG4105DFU	Cell wall formation (By similarity)
BBTM_02697	ENOG4106N3A	copper homeostasis protein cutc
BBTM_02699	ENOG4105E2R	ROK family
BBTM_02702	ENOG4105CE4	GlcNAc 6-P deacetylase
BBTM_02707	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BBTM_02712	ENOG4107T6F	Xaa-Pro aminopeptidase
BBTM_02717	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BBTM_02718	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BBTM_02721	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BBTM_02723	ENOG4105CG9	aspartate racemase
BBTM_02731	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BBTM_02733	ENOG4105EMN	RNA polymerase sigma factor
BBTM_02736	ENOG4107WI4	Aldose-1-epimerase
BBTM_02737	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BBTM_02739	ENOG4108Z66	YbaK ebsC protein
BBTM_02740	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BBTM_02746	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BBTM_02749	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BBTM_02750	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBTM_02753	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BBTM_02754	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BBTM_02758	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BBTM_02760	ENOG4108IYU	L-aspartate oxidase
BBTM_02762	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BBTM_02763	ENOG4107QI6	Cysteine desulfurase
BBTM_02764	ENOG4105CI3	gtp-binding protein typa
BBTM_02768	ENOG4105EVN	Prephenate dehydrogenase
BBTM_02781	ENOG4105CGK	Exodeoxyribonuclease III
BBTM_02786	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BBTM_02806	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
BBTM_02808	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BBTM_02810	ENOG4105EAC	phosphoserine phosphatase
BBTM_02813	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
BBTM_02815	ENOG4105E5F	proteasome
BBTM_02817	ENOG4105ECY	inositol monophosphatase
BBTM_02822	ENOG4108426	dNA-binding protein
BBTM_02826	ENOG4107QTF	adenylosuccinate lyase