locus-tag	class	description
BB0001	COG0445	tRNA wobble uridine modification
BB0002	COG0357	Ribosomal RNA small subunit methyltransferase G
BB0003	COG1192	Involved in chromosome partitioning
BB0005	COG1475	DNA binding
BB0006	COG0252	asparaginase activity
BB0007	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BB0008	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB0010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BB0011	COG0081	regulation of translation
BB0012	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BB0013	COG0222	ribosome binding
BB0014	COG0085	RNA polymerase activity
BB0015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BB0022	COG1230	cation diffusion facilitator family transporter
BB0024	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BB0025	COG0049	tRNA binding
BB0026	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BB0027	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BB0028	COG0051	transcription antitermination factor activity, RNA binding
BB0029	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BB0030	COG0088	Forms part of the polypeptide exit tunnel
BB0031	COG0089	rRNA binding
BB0032	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BB0033	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BB0034	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BB0035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BB0036	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BB0037	COG0255	Belongs to the universal ribosomal protein uL29 family
BB0038	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BB0041	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BB0042	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BB0043	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BB0044	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BB0045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BB0046	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BB0047	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BB0048	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BB0049	COG1841	ribosomal large subunit assembly
BB0050	COG0200	Binds to the 23S rRNA
BB0051	COG0201	protein transport
BB0052	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BB0053	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BB0054	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BB0055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BB0056	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BB0057	COG0202	RNA polymerase activity
BB0058	COG0203	ribosomal protein L17
BB0059	COG0537	adenosine 5'-monophosphoramidase activity
BB0060	COG1324	tolerance protein
BB0061	COG4232	protein-disulfide reductase activity
BB0064	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BB0066	COG1333	cytochrome c biogenesis protein
BB0067	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB0069	COG1965	Belongs to the frataxin family
BB0071	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BB0072	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BB0073	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BB0076	COG2814	Major facilitator Superfamily
BB0077	COG0629	single-stranded DNA binding
BB0086	COG0438	transferase activity, transferring glycosyl groups
BB0090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB0095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BB0096	COG2186	Transcriptional regulator
BB0100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB0101	COG1956	GAF domain-containing protein
BB0102	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB0108	COG0531	amino acid
BB0115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BB0116	COG3568	Endonuclease Exonuclease Phosphatase
BB0117	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB0119	COG0477	Major facilitator Superfamily
BB0121	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB0123	COG0367	asparagine synthase
BB0127	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BB0129	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB0136	COG0367	asparagine synthase
BB0137	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BB0142	COG0367	asparagine synthase
BB0144	COG0438	transferase activity, transferring glycosyl groups
BB0148	COG0438	transferase activity, transferring glycosyl groups
BB0149	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BB0150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BB0156	COG0859	PFAM glycosyl transferase family 9
BB0160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BB0163	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BB0164	COG1127	ABC transporter
BB0168	COG1686	Belongs to the peptidase S11 family
BB0171	COG0321	lipoyl(octanoyl) transferase activity
BB0172	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BB0176	COG2096	Adenosyltransferase
BB0178	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BB0179	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BB0180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BB0181	COG0523	cobalamin synthesis protein
BB0182	COG0735	belongs to the Fur family
BB0183	COG1121	(ABC) transporter
BB0185	COG0803	Belongs to the bacterial solute-binding protein 9 family
BB0187	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BB0190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BB0192	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BB0193	COG1560	Kdo2-lipid A biosynthetic process
BB0195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BB0198	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BB0199	COG1950	PFAM Membrane protein of
BB0201	COG0583	DNA-binding transcription factor activity
BB0203	COG0477	Major facilitator Superfamily
BB0207	COG0617	tRNA 3'-terminal CCA addition
BB0209	COG0513	Belongs to the DEAD box helicase family
BB0210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BB0211	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB0212	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BB0215	COG0735	belongs to the Fur family
BB0217	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BB0219	COG0438	transferase activity, transferring glycosyl groups
BB0224	COG0640	Transcriptional regulator
BB0232	COG0411	ABC transporter
BB0236	COG0583	DNA-binding transcription factor activity
BB0239	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BB0240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB0241	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB0244	COG0758	DNA mediated transformation
BB0245	COG1522	sequence-specific DNA binding
BB0247	COG0242	peptide deformylase activity
BB0248	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB0250	COG0546	phosphoglycolate phosphatase activity
BB0254	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BB0255	COG1942	4-Oxalocrotonate Tautomerase
BB0256	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB0260	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BB0262	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BB0262	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB0264	COG5000	phosphorelay sensor kinase activity
BB0265	COG2204	response regulator
BB0266	COG0569	domain protein
BB0270	COG2068	MobA-Related Protein
BB0272	COG3473	Maleate cis-trans isomerase
BB0273	COG0596	Alpha beta hydrolase
BB0274	COG2309	aminopeptidase activity
BB0275	COG1335	isochorismatase
BB0280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB0285	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB0286	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB0289	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BB0290	COG2226	methyltransferase
BB0293	COG3181	Tripartite tricarboxylate transporter family receptor
BB0294	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BB0295	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BB0296	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB0298	COG0588	phosphoglycerate mutase activity
BB0299	COG4942	peptidase
BB0300	COG0793	Belongs to the peptidase S41A family
BB0301	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BB0304	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BB0305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB0311	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BB0312	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BB0313	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BB0314	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BB0316	COG0142	geranyltranstransferase activity
BB0317	COG0583	DNA-binding transcription factor activity
BB0319	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BB0320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB0323	COG2994	toxin metabolic process
BB0324	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BB0325	COG2274	protein secretion by the type I secretion system
BB0326	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB0327	COG1538	Outer membrane efflux protein
BB0330	COG0765	amino acid transport
BB0331	COG0765	amino acid transport
BB0332	COG1126	abc transporter atp-binding protein
BB0336	COG1028	Short-chain dehydrogenase reductase Sdr
BB0338	COG1802	Transcriptional regulator
BB0341	COG1802	Transcriptional regulator
BB0343	COG0318	PFAM AMP-dependent synthetase and ligase
BB0345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB0347	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB0349	COG0028	Belongs to the TPP enzyme family
BB0351	COG0583	DNA-binding transcription factor activity
BB0352	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0353	COG2301	Belongs to the HpcH HpaI aldolase family
BB0354	COG2188	Transcriptional regulator
BB0363	COG0583	DNA-binding transcription factor activity
BB0364	COG1024	Enoyl-CoA hydratase
BB0367	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB0369	COG0411	ABC transporter
BB0371	COG1028	Short-chain dehydrogenase reductase Sdr
BB0373	COG1028	Short-chain dehydrogenase reductase Sdr
BB0374	COG1902	pentaerythritol trinitrate reductase activity
BB0379	COG0745	RESPONSE REGULATOR receiver
BB0383	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BB0384	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BB0385	COG2890	protein-(glutamine-N5) methyltransferase activity
BB0386	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BB0388	COG3181	Tripartite tricarboxylate transporter family receptor
BB0395	COG1464	Belongs to the NlpA lipoprotein family
BB0399	COG0410	ABC transporter
BB0402	COG4211	Belongs to the binding-protein-dependent transport system permease family
BB0403	COG0583	DNA-binding transcription factor activity
BB0404	COG0683	leucine binding
BB0405	COG0154	amidase activity
BB0406	COG0288	reversible hydration of carbon dioxide
BB0410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB0413	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BB0415	COG1414	Transcriptional regulator
BB0416	COG1028	Short-chain dehydrogenase reductase Sdr
BB0417	COG2031	fatty acid transporter
BB0418	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB0420	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BB0421	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BB0423	COG4257	antibiotic catabolic process
BB0424	COG2808	Putative FMN-binding domain
BB0425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB0426	COG0747	negative chemotaxis
BB0427	COG0657	acetylesterase activity
BB0429	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB0430	COG2207	Transcriptional regulator
BB0431	COG0129	dihydroxy-acid dehydratase activity
BB0432	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BB0433	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BB0435	COG1538	Outer membrane efflux protein
BB0438	COG0583	DNA-binding transcription factor activity
BB0439	COG0628	permease
BB0441	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BB0442	COG0251	oxidation-reduction process
BB0444	COG0330	HflC and HflK could
BB0448	COG0583	DNA-binding transcription factor activity
BB0454	COG3181	Tripartite tricarboxylate transporter family receptor
BB0455	COG0318	PFAM AMP-dependent synthetase and ligase
BB0456	COG1414	Transcriptional regulator
BB0457	COG1024	Enoyl-CoA hydratase
BB0458	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB0460	COG0604	alcohol dehydrogenase
BB0461	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0462	COG0583	DNA-binding transcription factor activity
BB0464	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0467	COG0251	oxidation-reduction process
BB0468	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB0468	COG1017	nitric oxide dioxygenase activity
BB0469	COG2031	fatty acid transporter
BB0472	COG1278	Cold shock
BB0473	COG0583	DNA-binding transcription factor activity
BB0475	COG3119	arylsulfatase activity
BB0478	COG1228	amidohydrolase
BB0479	COG0523	cobalamin synthesis protein
BB0480	COG1819	glycosyl
BB0496	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB0501	COG0326	Molecular chaperone. Has ATPase activity
BB0502	COG0625	glutathione transferase activity
BB0505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB0506	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BB0507	COG1652	LysM domain
BB0510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BB0512	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0519	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB0530	COG0583	DNA-binding transcription factor activity
BB0531	COG3181	Tripartite tricarboxylate transporter family receptor
BB0532	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BB0533	COG1024	Enoyl-CoA hydratase
BB0534	COG3181	Tripartite tricarboxylate transporter family receptor
BB0539	COG0028	Belongs to the TPP enzyme family
BB0540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0541	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB0541	COG1024	Enoyl-CoA hydratase
BB0542	COG3181	Tripartite tricarboxylate transporter family receptor
BB0543	COG1414	Transcriptional regulator
BB0547	COG0318	PFAM AMP-dependent synthetase and ligase
BB0548	COG1609	Transcriptional regulator
BB0554	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB0555	COG1024	Enoyl-CoA hydratase
BB0558	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0559	COG3181	Tripartite tricarboxylate transporter family receptor
BB0560	COG0583	DNA-binding transcription factor activity
BB0563	COG1960	acyl-CoA dehydrogenase activity
BB0566	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB0567	COG0583	DNA-binding transcription factor activity
BB0568	COG3976	FMN-binding domain protein
BB0568	COG1053	succinate dehydrogenase
BB0571	COG0410	ABC transporter
BB0575	COG0683	leucine binding
BB0576	COG1309	transcriptional regulator
BB0580	COG1028	Short-chain dehydrogenase reductase Sdr
BB0581	COG1960	acyl-CoA dehydrogenase activity
BB0582	COG1028	Short-chain dehydrogenase reductase Sdr
BB0583	COG0318	PFAM AMP-dependent synthetase and ligase
BB0585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BB0587	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BB0590	COG2030	dehydratase
BB0592	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0593	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0594	COG3181	Tripartite tricarboxylate transporter family receptor
BB0599	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB0601	COG0411	ABC transporter
BB0603	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB0603	COG1902	pentaerythritol trinitrate reductase activity
BB0604	COG1028	Short-chain dehydrogenase reductase Sdr
BB0606	COG0427	acetyl-CoA hydrolase
BB0607	COG0318	PFAM AMP-dependent synthetase and ligase
BB0610	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BB0611	COG1960	acyl-CoA dehydrogenase activity
BB0614	COG0183	Belongs to the thiolase family
BB0615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB0617	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0618	COG0583	DNA-binding transcription factor activity
BB0619	COG1960	acyl-CoA dehydrogenase activity
BB0622	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BB0627	COG1309	transcriptional regulator
BB0629	COG1024	Enoyl-CoA hydratase
BB0633	COG1024	Enoyl-CoA hydratase
BB0634	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0635	COG3181	Tripartite tricarboxylate transporter family receptor
BB0636	COG1454	alcohol dehydrogenase
BB0637	COG1024	Enoyl-CoA hydratase
BB0641	COG1012	belongs to the aldehyde dehydrogenase family
BB0642	COG0431	NADPH-dependent FMN reductase
BB0643	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB0644	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB0647	COG1414	Transcriptional regulator
BB0648	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB0649	COG1028	Short-chain dehydrogenase reductase Sdr
BB0650	COG3181	Tripartite tricarboxylate transporter family receptor
BB0651	COG1012	belongs to the aldehyde dehydrogenase family
BB0653	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB0656	COG1960	acyl-CoA dehydrogenase activity
BB0663	COG1960	acyl-CoA dehydrogenase activity
BB0664	COG1024	Enoyl-CoA hydratase
BB0665	COG0183	Belongs to the thiolase family
BB0666	COG3181	Tripartite tricarboxylate transporter family receptor
BB0669	COG0583	DNA-binding transcription factor activity
BB0670	COG2267	carboxylic ester hydrolase activity
BB0673	COG0625	glutathione transferase activity
BB0674	COG3181	Tripartite tricarboxylate transporter family receptor
BB0676	COG2186	Transcriptional regulator
BB0677	COG1012	belongs to the aldehyde dehydrogenase family
BB0678	COG0626	cystathionine gamma-synthase activity
BB0686	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB0691	COG1473	amidohydrolase
BB0692	COG1414	Transcriptional regulator
BB0694	COG0154	amidase activity
BB0706	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB0708	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB0709	COG3135	benzoate transporter
BB0714	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB0715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0716	COG1335	isochorismatase
BB0719	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB0726	COG3181	Tripartite tricarboxylate transporter family receptor
BB0727	COG0633	Ferredoxin
BB0727	COG0543	2 iron, 2 sulfur cluster binding
BB0728	COG4638	Rieske (2fe-2S)
BB0729	COG1028	Short-chain dehydrogenase reductase Sdr
BB0732	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB0736	COG1012	belongs to the aldehyde dehydrogenase family
BB0737	COG3384	dioxygenase
BB0739	COG3971	2-oxopent-4-enoate hydratase activity
BB0750	COG1024	Enoyl-CoA hydratase
BB0751	COG1028	Short-chain dehydrogenase reductase Sdr
BB0752	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0755	COG1960	acyl-CoA dehydrogenase activity
BB0759	COG0411	ABC transporter
BB0765	COG0183	Belongs to the thiolase family
BB0768	COG3181	Tripartite tricarboxylate transporter family receptor
BB0770	COG1414	Transcriptional regulator
BB0771	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB0780	COG1459	type II secretion system
BB0781	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BB0782	COG3409	Peptidoglycan-binding domain 1 protein
BB0782	COG3267	Type II secretory pathway component ExeA
BB0784	COG1450	Type ii and iii secretion system protein
BB0793	COG3501	Rhs element vgr protein
BB0797	COG5444	nuclease activity
BB0819	COG0387	Pfam Sodium calcium exchanger
BB0821	COG3468	outer membrane autotransporter barrel domain protein
BB0822	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB0823	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BB0832	COG4772	TonB-dependent receptor
BB0834	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB0840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB0840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB0842	COG0489	protein tyrosine kinase activity
BB0845	COG0717	Belongs to the dCTP deaminase family
BB0850	COG1982	Orn Lys Arg decarboxylase major
BB0851	COG2081	HI0933 family
BB0852	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB0854	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BB0855	COG0509	glycine decarboxylation via glycine cleavage system
BB0856	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB0856	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB0860	COG1024	Enoyl-CoA hydratase
BB0864	COG4172	Belongs to the ABC transporter superfamily
BB0865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB0866	COG0601	transmembrane transport
BB0867	COG0747	negative chemotaxis
BB0870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB0872	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BB0874	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BB0875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB0876	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BB0879	COG0438	transferase activity, transferring glycosyl groups
BB0882	COG0438	transferase activity, transferring glycosyl groups
BB0883	COG0438	transferase activity, transferring glycosyl groups
BB0884	COG0166	Belongs to the GPI family
BB0887	COG0277	FAD linked oxidase domain protein
BB0888	COG0745	RESPONSE REGULATOR receiver
BB0889	COG0642	Histidine kinase
BB0890	COG1368	sulfuric ester hydrolase activity
BB0892	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BB0897	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB0899	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BB0900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BB0901	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BB0902	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BB0903	COG0193	aminoacyl-tRNA hydrolase activity
BB0905	COG0012	GTP binding
BB0906	COG0582	viral genome integration into host DNA
BB0910	COG0464	growth
BB0911	COG1404	Belongs to the peptidase S8 family
BB0917	COG0745	RESPONSE REGULATOR receiver
BB0918	COG3181	Tripartite tricarboxylate transporter family receptor
BB0919	COG1309	transcriptional regulator
BB0921	COG2814	Major facilitator Superfamily
BB0926	COG0281	malic enzyme
BB0926	COG0280	phosphate acetyltransferase
BB0928	COG0601	transmembrane transport
BB0929	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB0930	COG4172	Belongs to the ABC transporter superfamily
BB0931	COG0747	negative chemotaxis
BB0933	COG0583	DNA-binding transcription factor activity
BB0936	COG0640	Transcriptional regulator
BB0939	COG3135	benzoate transporter
BB0940	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BB0941	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BB0942	COG0742	ribosomal rna small subunit methyltransferase
BB0945	COG3639	organic phosphonate transmembrane transporter activity
BB0946	COG3639	organic phosphonate transmembrane transporter activity
BB0947	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BB0952	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BB0953	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB0955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BB0956	COG1546	Belongs to the CinA family
BB0956	COG1058	Belongs to the CinA family
BB0957	COG0284	orotidine-5'-phosphate decarboxylase activity
BB0958	COG1252	NADH dehydrogenase
BB0962	COG0459	protein refolding
BB0963	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BB0967	COG1053	succinate dehydrogenase
BB0969	COG0583	DNA-binding transcription factor activity
BB0971	COG3181	Tripartite tricarboxylate transporter family receptor
BB0972	COG1414	Transcriptional regulator
BB0975	COG1335	isochorismatase
BB0978	COG0405	Gamma-glutamyltransferase
BB0981	COG1960	acyl-CoA dehydrogenase activity
BB0982	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB0983	COG3181	Tripartite tricarboxylate transporter family receptor
BB0984	COG0583	DNA-binding transcription factor activity
BB0989	COG3181	Tripartite tricarboxylate transporter family receptor
BB0990	COG0583	DNA-binding transcription factor activity
BB0991	COG5001	Diguanylate cyclase
BB0996	COG3842	ATPase activity
BB1001	COG1024	Enoyl-CoA hydratase
BB1001	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB1002	COG0318	PFAM AMP-dependent synthetase and ligase
BB1005	COG4172	Belongs to the ABC transporter superfamily
BB1008	COG0747	negative chemotaxis
BB1012	COG2423	ornithine cyclodeaminase activity
BB1014	COG0473	3-isopropylmalate dehydrogenase activity
BB1015	COG0066	3-isopropylmalate dehydratase activity
BB1016	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB1018	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB1020	COG0583	DNA-binding transcription factor activity
BB1024	COG0583	DNA-binding transcription factor activity
BB1025	COG3119	arylsulfatase activity
BB1027	COG0583	DNA-binding transcription factor activity
BB1029	COG1024	Enoyl-CoA hydratase
BB1031	COG2084	Dehydrogenase
BB1035	COG1850	ribulose-bisphosphate carboxylase activity
BB1037	COG0583	DNA-binding transcription factor activity
BB1038	COG1024	Enoyl-CoA hydratase
BB1043	COG3842	ATPase activity
BB1044	COG1177	transmembrane transport
BB1047	COG3181	Tripartite tricarboxylate transporter family receptor
BB1048	COG3386	PFAM SMP-30 Gluconolaconase
BB1050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB1054	COG0583	DNA-binding transcription factor activity
BB1056	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB1059	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB1060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB1064	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB1067	COG3181	Tripartite tricarboxylate transporter family receptor
BB1071	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB1074	COG1802	Transcriptional regulator
BB1075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB1080	COG1335	isochorismatase
BB1081	COG0583	DNA-binding transcription factor activity
BB1083	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB1087	COG1024	Enoyl-CoA hydratase
BB1088	COG1028	Short-chain dehydrogenase reductase Sdr
BB1089	COG1024	Enoyl-CoA hydratase
BB1090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB1091	COG0583	DNA-binding transcription factor activity
BB1092	COG3181	Tripartite tricarboxylate transporter family receptor
BB1096	COG0583	DNA-binding transcription factor activity
BB1097	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB1098	COG1960	acyl-CoA dehydrogenase activity
BB1099	COG3181	Tripartite tricarboxylate transporter family receptor
BB1100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB1101	COG4191	Histidine kinase
BB1102	COG4566	intracellular signal transduction
BB1108	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB1109	COG1304	FMN binding
BB1110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BB1116	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB1119	COG0583	DNA-binding transcription factor activity
BB1123	COG1024	Enoyl-CoA hydratase
BB1124	COG1024	Enoyl-CoA hydratase
BB1125	COG0318	PFAM AMP-dependent synthetase and ligase
BB1126	COG1960	acyl-CoA dehydrogenase activity
BB1134	COG3685	Protein conserved in bacteria
BB1136	COG0387	Pfam Sodium calcium exchanger
BB1137	COG3795	YCII-related domain
BB1142	COG0154	amidase activity
BB1143	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB1144	COG1024	Enoyl-CoA hydratase
BB1146	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB1149	COG1028	Short-chain dehydrogenase reductase Sdr
BB1150	COG1414	Transcriptional regulator
BB1153	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB1154	COG0251	oxidation-reduction process
BB1155	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB1158	COG0410	ABC transporter
BB1159	COG1902	pentaerythritol trinitrate reductase activity
BB1162	COG0590	tRNA wobble adenosine to inosine editing
BB1163	COG2807	transmembrane transport
BB1165	COG3181	Tripartite tricarboxylate transporter family receptor
BB1166	COG0154	amidase activity
BB1167	COG0307	riboflavin synthase, alpha
BB1168	COG3181	Tripartite tricarboxylate transporter family receptor
BB1169	COG1522	sequence-specific DNA binding
BB1171	COG0318	PFAM AMP-dependent synthetase and ligase
BB1173	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB1175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB1177	COG1063	alcohol dehydrogenase
BB1181	COG1418	mRNA catabolic process
BB1182	COG1448	Aminotransferase
BB1183	COG1335	isochorismatase
BB1188	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB1189	COG2274	protein secretion by the type I secretion system
BB1191	COG1538	Outer membrane efflux protein
BB1194	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BB1196	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB1198	COG1309	transcriptional regulator
BB1199	COG1960	acyl-CoA dehydrogenase activity
BB1200	COG1028	Short-chain dehydrogenase reductase Sdr
BB1201	COG2076	Multidrug Resistance protein
BB1202	COG1309	transcriptional regulator
BB1204	COG0583	DNA-binding transcription factor activity
BB1208	COG0840	transmembrane signaling receptor activity
BB1211	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB1216	COG1012	belongs to the aldehyde dehydrogenase family
BB1218	COG1024	Enoyl-CoA hydratase
BB1220	COG2199	diguanylate cyclase activity
BB1220	COG2203	Gaf domain
BB1223	COG0456	acetyltransferase
BB1225	COG0154	amidase activity
BB1228	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB1231	COG3945	hemerythrin HHE cation binding domain
BB1234	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB1234	COG2169	Transcriptional regulator
BB1238	COG1271	oxidase subunit
BB1239	COG1294	oxidase, subunit
BB1241	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB1248	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BB1254	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB1256	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BB1257	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BB1259	COG2070	2-Nitropropane dioxygenase
BB1262	COG2207	Transcriptional regulator
BB1262	COG1917	Cupin 2, conserved barrel domain protein
BB1266	COG2900	Belongs to the SlyX family
BB1267	COG1671	Belongs to the UPF0178 family
BB1268	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB1274	COG0583	DNA-binding transcription factor activity
BB1277	COG0583	DNA-binding transcription factor activity
BB1282	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BB1284	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB1285	COG1845	cytochrome c oxidase, subunit III
BB1286	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BB1287	COG0640	Transcriptional regulator
BB1291	COG3220	belongs to the UPF0276 family
BB1297	COG4942	peptidase
BB1305	COG1028	Short-chain dehydrogenase reductase Sdr
BB1307	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BB1308	COG1845	cytochrome c oxidase, subunit III
BB1309	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB1310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BB1311	COG0477	Major facilitator Superfamily
BB1314	COG5006	permease, DMT superfamily
BB1318	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BB1320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BB1321	COG3383	formate dehydrogenase (NAD+) activity
BB1325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BB1326	COG0303	'Molybdopterin
BB1327	COG0521	Mo-molybdopterin cofactor biosynthetic process
BB1329	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BB1330	COG0315	cyclic pyranopterin monophosphate synthase activity
BB1332	COG0412	Dienelactone hydrolase
BB1334	COG0678	peroxiredoxin activity
BB1336	COG0697	spore germination
BB1337	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BB1342	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BB1343	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB1344	COG1335	isochorismatase
BB1345	COG0523	cobalamin synthesis protein
BB1347	COG1053	succinate dehydrogenase
BB1351	COG1802	Transcriptional regulator
BB1352	COG0667	Aldo Keto reductase
BB1353	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BB1354	COG4535	Mg2 and Co2 transporter CorC
BB1355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BB1356	COG1702	phosphate starvation-inducible protein PhoH
BB1357	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BB1359	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB1360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB1361	COG1862	Preprotein translocase
BB1362	COG0343	queuine tRNA-ribosyltransferase activity
BB1363	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BB1364	COG2027	D-alanyl-D-alanine carboxypeptidase
BB1365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BB1366	COG3468	outer membrane autotransporter barrel domain protein
BB1367	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BB1367	COG1648	precorrin-2 dehydrogenase activity
BB1372	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BB1373	COG0741	lytic transglycosylase activity
BB1374	COG0436	Aminotransferase
BB1376	COG0280	phosphate acetyltransferase
BB1376	COG0281	malic enzyme
BB1378	COG2732	(Barnase) inhibitor
BB1379	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BB1380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BB1381	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BB1382	COG0126	phosphoglycerate kinase activity
BB1383	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BB1384	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BB1387	COG0625	glutathione transferase activity
BB1393	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BB1395	COG0306	phosphate transporter
BB1396	COG0521	Mo-molybdopterin cofactor biosynthetic process
BB1398	COG0739	heme binding
BB1400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BB1410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BB1412	COG2944	sequence-specific DNA binding
BB1414	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BB1415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BB1416	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BB1417	COG0009	L-threonylcarbamoyladenylate synthase
BB1418	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB1419	COG1414	Transcriptional regulator
BB1422	COG0765	amino acid transport
BB1423	COG1126	abc transporter atp-binding protein
BB1424	COG0028	Belongs to the TPP enzyme family
BB1427	COG0028	Belongs to the TPP enzyme family
BB1428	COG0583	DNA-binding transcription factor activity
BB1429	COG4974	Belongs to the 'phage' integrase family
BB1430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BB1431	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BB1433	COG1686	Belongs to the peptidase S11 family
BB1437	COG1074	ATP-dependent DNA helicase activity
BB1438	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BB1440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BB1441	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB1442	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB1444	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB1445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BB1446	COG0505	Belongs to the CarA family
BB1447	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BB1448	COG4221	oxidoreductase activity
BB1449	COG0406	alpha-ribazole phosphatase activity
BB1451	COG3842	ATPase activity
BB1455	COG2233	PERMEase
BB1456	COG0840	transmembrane signaling receptor activity
BB1457	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB1458	COG1534	Rna-binding protein
BB1459	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BB1460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB1462	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BB1464	COG0248	Ppx GppA phosphatase
BB1469	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BB1471	COG3181	Tripartite tricarboxylate transporter family receptor
BB1473	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB1474	COG3620	sequence-specific DNA binding
BB1486	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB1492	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB1499	COG2072	flavoprotein involved in K transport
BB1500	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB1506	COG1137	ATPase activity
BB1508	COG0154	amidase activity
BB1509	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB1512	COG1028	Short-chain dehydrogenase reductase Sdr
BB1513	COG1028	Short-chain dehydrogenase reductase Sdr
BB1514	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB1515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB1516	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB1518	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB1520	COG1522	sequence-specific DNA binding
BB1521	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB1522	COG1473	amidohydrolase
BB1523	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB1524	COG4597	amino acid ABC transporter
BB1525	COG0765	amino acid transport
BB1526	COG1126	abc transporter atp-binding protein
BB1529	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB1535	COG3181	Tripartite tricarboxylate transporter family receptor
BB1538	COG2985	domain, Protein
BB1539	COG0583	DNA-binding transcription factor activity
BB1546	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB1550	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB1554	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB1556	COG1132	(ABC) transporter
BB1557	COG0500	methyltransferase
BB1561	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BB1563	COG1012	belongs to the aldehyde dehydrogenase family
BB1564	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BB1566	COG0511	ligase activity, forming carbon-carbon bonds
BB1571	COG2188	Transcriptional regulator
BB1572	COG0439	Biotin carboxylase
BB1574	COG0511	ligase activity, forming carbon-carbon bonds
BB1577	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB1583	COG3971	2-oxopent-4-enoate hydratase activity
BB1584	COG0583	DNA-binding transcription factor activity
BB1587	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB1593	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB1595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BB1597	COG1028	Short-chain dehydrogenase reductase Sdr
BB1605	COG0251	oxidation-reduction process
BB1606	COG1902	pentaerythritol trinitrate reductase activity
BB1612	COG4789	Type iii secretion
BB1625	COG4669	(LipO)protein
BB1631	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BB1632	COG4790	Type iii secretion
BB1633	COG4794	Type iii secretion
BB1634	COG4791	protein targeting
BB1635	COG4792	protein secretion
BB1638	COG1595	DNA-templated transcription, initiation
BB1642	COG2770	Histidine kinase
BB1642	COG2208	phosphoserine phosphatase activity
BB1644	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB1645	COG2172	sigma factor antagonist activity
BB1646	COG1366	Belongs to the anti-sigma-factor antagonist family
BB1647	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB1653	COG2321	neutral zinc metallopeptidase
BB1654	COG0009	L-threonylcarbamoyladenylate synthase
BB1655	COG1994	Peptidase M50
BB1656	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB1657	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BB1658	COG3539	Fimbrial protein
BB1659	COG2850	peptidyl-arginine hydroxylation
BB1660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BB1674	COG1475	DNA binding
BB1693	COG4695	Portal protein
BB1694	COG0740	serine-type endopeptidase activity
BB1718	COG3360	Dodecin
BB1725	COG0668	transmembrane transport
BB1730	COG1253	flavin adenine dinucleotide binding
BB1731	COG1968	undecaprenyl-diphosphatase activity
BB1732	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BB1734	COG3063	Type IV pilus biogenesis stability protein PilW
BB1735	COG0215	cysteine-tRNA ligase activity
BB1737	COG0825	malonyl-CoA metabolic process
BB1738	COG0037	tRNA processing
BB1739	COG0527	aspartate kinase activity
BB1743	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB1746	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB1747	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BB1748	COG1028	Short-chain dehydrogenase reductase Sdr
BB1750	COG0583	DNA-binding transcription factor activity
BB1753	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB1755	COG3842	ATPase activity
BB1756	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB1756	COG1902	pentaerythritol trinitrate reductase activity
BB1757	COG1414	Transcriptional regulator
BB1758	COG1832	CoA-binding protein
BB1760	COG0251	oxidation-reduction process
BB1765	COG1902	pentaerythritol trinitrate reductase activity
BB1767	COG1215	transferase activity, transferring glycosyl groups
BB1768	COG1649	PFAM Uncharacterised BCR, COG1649
BB1768	COG0726	polysaccharide deacetylase
BB1771	COG1846	Transcriptional regulator
BB1776	COG2010	Cytochrome c
BB1776	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BB1777	COG2080	2 iron, 2 sulfur cluster binding
BB1779	COG3473	Maleate cis-trans isomerase
BB1780	COG0596	Alpha beta hydrolase
BB1781	COG2309	aminopeptidase activity
BB1782	COG1335	isochorismatase
BB1783	COG2010	Cytochrome c
BB1783	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BB1784	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB1784	COG1017	nitric oxide dioxygenase activity
BB1787	COG3181	Tripartite tricarboxylate transporter family receptor
BB1789	COG0318	PFAM AMP-dependent synthetase and ligase
BB1791	COG0183	Belongs to the thiolase family
BB1792	COG1024	Enoyl-CoA hydratase
BB1792	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB1795	COG0183	Belongs to the thiolase family
BB1798	COG2197	response regulator
BB1801	COG0166	Belongs to the GPI family
BB1802	COG1045	serine acetyltransferase
BB1804	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BB1805	COG0483	inositol monophosphate 1-phosphatase activity
BB1807	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BB1810	COG0210	DNA helicase
BB1811	COG0598	Magnesium transport protein CorA
BB1813	COG0747	negative chemotaxis
BB1814	COG0601	transmembrane transport
BB1815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB1816	COG4172	Belongs to the ABC transporter superfamily
BB1817	COG1846	Transcriptional regulator
BB1826	COG4964	Belongs to the GSP D family
BB1839	COG3474	cytochrome
BB1840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BB1843	COG3384	dioxygenase
BB1844	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BB1848	COG2885	chlorophyll binding
BB1855	COG0697	spore germination
BB1856	COG0730	response to heat
BB1859	COG3264	Mechanosensitive ion channel
BB1859	COG1511	domain protein
BB1860	COG0583	DNA-binding transcription factor activity
BB1861	COG0427	acetyl-CoA hydrolase
BB1862	COG0385	Bile acid
BB1864	COG3468	outer membrane autotransporter barrel domain protein
BB1865	COG0424	maF-like protein
BB1866	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BB1867	COG0799	negative regulation of ribosome biogenesis
BB1868	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BB1869	COG0408	coproporphyrinogen oxidase activity
BB1870	COG0151	Belongs to the GarS family
BB1871	COG0217	transcriptional regulatory protein
BB1872	COG0433	COG0433 Predicted ATPase
BB1873	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB1875	COG1012	belongs to the aldehyde dehydrogenase family
BB1880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BB1882	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB1884	COG0747	negative chemotaxis
BB1886	COG0473	3-isopropylmalate dehydrogenase activity
BB1887	COG2814	Major facilitator Superfamily
BB1888	COG1566	PFAM secretion protein HlyD family protein
BB1890	COG1846	Transcriptional regulator
BB1892	COG0697	spore germination
BB1894	COG0501	Belongs to the peptidase M48B family
BB1898	COG0583	DNA-binding transcription factor activity
BB1899	COG3842	ATPase activity
BB1900	COG1178	ABC-type Fe3 transport system permease component
BB1901	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB1902	COG1840	ABC-type Fe3 transport system, periplasmic component
BB1908	COG3181	Tripartite tricarboxylate transporter family receptor
BB1910	COG1722	exodeoxyribonuclease VII activity
BB1911	COG0142	geranyltranstransferase activity
BB1912	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BB1913	COG1469	GTP cyclohydrolase I activity
BB1914	COG0360	Binds together with S18 to 16S ribosomal RNA
BB1915	COG2965	DNA replication, synthesis of RNA primer
BB1916	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BB1917	COG0359	binds to the 23S rRNA
BB1919	COG0305	Participates in initiation and elongation during chromosome replication
BB1921	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BB1922	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BB1923	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BB1924	COG3737	Protein of unknown function (DUF498/DUF598)
BB1925	COG0436	Aminotransferase
BB1929	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BB1930	COG0308	aminopeptidase N
BB1933	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB1934	COG0312	modulator of DNA gyrase
BB1935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB1936	COG3064	Membrane
BB1936	COG3210	domain, Protein
BB1936	COG3064	Membrane
BB1936	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB1936	COG3210	domain, Protein
BB1936	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB1937	COG0277	FAD linked oxidase domain protein
BB1938	COG0277	FAD linked oxidase domain protein
BB1939	COG0277	FAD linked oxidase domain protein
BB1940	COG0247	lactate metabolic process
BB1941	COG2819	hydrolase of the alpha beta superfamily
BB1944	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BB1945	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BB1946	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BB1949	COG0583	DNA-binding transcription factor activity
BB1950	COG0482	sulfurtransferase activity
BB1951	COG0730	response to heat
BB1952	COG0625	glutathione transferase activity
BB1953	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BB1954	COG3909	cytochrome
BB1960	COG3706	GGDEF domain
BB1966	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BB1967	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BB1969	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB1970	COG0069	glutamate synthase activity
BB1971	COG2391	methyltransferase activity
BB1972	COG0679	Auxin Efflux Carrier
BB1973	COG2153	protein acetylation
BB1975	COG0557	exoribonuclease II activity
BB1976	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB1978	COG3128	pkhd-type hydroxylase
BB1979	COG0776	regulation of translation
BB1983	COG0745	RESPONSE REGULATOR receiver
BB1984	COG0642	Histidine kinase
BB1985	COG3158	transport of potassium into the cell
BB1986	COG0137	argininosuccinate synthase activity
BB1987	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BB1988	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB1990	COG0583	DNA-binding transcription factor activity
BB1992	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB1996	COG2186	Transcriptional regulator
BB1997	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BB2001	COG0268	Binds directly to 16S ribosomal RNA
BB2003	COG0728	peptidoglycan biosynthetic process
BB2005	COG0563	adenylate kinase activity
BB2006	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BB2007	COG2835	tetraacyldisaccharide 4'-kinase activity
BB2008	COG1663	tetraacyldisaccharide 4'-kinase activity
BB2009	COG0848	biopolymer transport protein
BB2010	COG0811	peptide transport
BB2011	COG1570	exodeoxyribonuclease VII activity
BB2012	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB2014	COG0183	Belongs to the thiolase family
BB2016	COG1278	Cold shock
BB2017	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BB2019	COG4953	penicillin-binding protein 1C
BB2020	COG0542	response to heat
BB2021	COG2995	paraquat-inducible protein a
BB2022	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BB2022	COG3008	intermembrane lipid transfer
BB2024	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BB2024	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BB2024	COG0506	proline dehydrogenase activity
BB2026	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB2030	COG2271	Major facilitator Superfamily
BB2031	COG1309	transcriptional regulator
BB2033	COG3468	outer membrane autotransporter barrel domain protein
BB2034	COG0004	ammonium transporteR
BB2038	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BB2039	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BB2040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BB2041	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB2041	COG0072	phenylalanine-tRNA ligase activity
BB2042	COG0776	regulation of translation
BB2046	COG0500	methyltransferase
BB2049	COG2367	Beta-lactamase
BB2051	COG1522	sequence-specific DNA binding
BB2054	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB2060	COG0540	Belongs to the ATCase OTCase family
BB2061	COG2974	May be involved in recombination
BB2063	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB2064	COG0583	DNA-binding transcription factor activity
BB2065	COG0183	Belongs to the thiolase family
BB2068	COG1028	Short-chain dehydrogenase reductase Sdr
BB2071	COG3842	ATPase activity
BB2072	COG1024	Enoyl-CoA hydratase
BB2072	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB2074	COG0642	Histidine kinase
BB2076	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BB2077	COG2137	regulation of response to DNA damage stimulus
BB2078	COG0583	DNA-binding transcription factor activity
BB2079	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BB2081	COG0045	succinate-CoA ligase (ADP-forming) activity
BB2082	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BB2083	COG0861	Integral membrane protein TerC family
BB2084	COG0861	Integral membrane protein TerC family
BB2085	COG0181	hydroxymethylbilane synthase activity
BB2089	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BB2097	COG4964	Belongs to the GSP D family
BB2103	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BB2105	COG1295	ribonuclease BN
BB2107	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BB2108	COG0745	RESPONSE REGULATOR receiver
BB2109	COG2205	protein histidine kinase activity
BB2110	COG5001	Diguanylate cyclase
BB2110	COG3300	MHYT domain
BB2111	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BB2112	COG4783	chaperone-mediated protein folding
BB2113	COG1763	Mo-molybdopterin cofactor biosynthetic process
BB2114	COG0303	'Molybdopterin
BB2115	COG0746	molybdenum cofactor guanylyltransferase activity
BB2116	COG0489	protein tyrosine kinase activity
BB2121	COG3383	formate dehydrogenase (NAD+) activity
BB2121	COG0243	molybdopterin cofactor binding
BB2122	COG0437	4 iron, 4 sulfur cluster binding
BB2128	COG1122	ATPase activity
BB2130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB2131	COG0066	3-isopropylmalate dehydratase activity
BB2132	COG0473	3-isopropylmalate dehydrogenase activity
BB2133	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BB2135	COG0101	tRNA pseudouridine synthase activity
BB2136	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB2139	COG0135	phosphoribosylanthranilate isomerase activity
BB2145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB2147	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB2149	COG2197	response regulator
BB2150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BB2151	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BB2152	COG0189	ligase activity
BB2154	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB2155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB2157	COG1764	response to oxidative stress
BB2158	COG2423	ornithine cyclodeaminase activity
BB2160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB2161	COG0765	amino acid transport
BB2162	COG0765	amino acid transport
BB2163	COG1126	abc transporter atp-binding protein
BB2164	COG0756	dUTP diphosphatase activity
BB2166	COG0586	Pfam SNARE associated Golgi protein
BB2168	COG1522	sequence-specific DNA binding
BB2170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BB2171	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BB2172	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BB2173	COG0196	riboflavin kinase activity
BB2174	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BB2175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BB2175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB2178	COG0210	DNA helicase
BB2179	COG4771	TonB-dependent receptor
BB2180	COG0488	(ABC) transporter
BB2181	COG2890	protein-(glutamine-N5) methyltransferase activity
BB2182	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB2183	COG2171	N-acyltransferase activity
BB2184	COG0436	Aminotransferase
BB2185	COG0582	viral genome integration into host DNA
BB2192	COG3723	Recombinational DNA repair protein, rece pathway
BB2230	COG1196	nuclear chromosome segregation
BB2244	COG2135	peptidase activity
BB2249	COG1278	Cold shock
BB2251	COG1278	Cold shock
BB2253	COG0544	peptidyl-prolyl cis-trans isomerase activity
BB2254	COG0740	serine-type endopeptidase activity
BB2255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BB2256	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BB2257	COG0583	DNA-binding transcription factor activity
BB2258	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB2261	COG1024	Enoyl-CoA hydratase
BB2263	COG0183	Belongs to the thiolase family
BB2264	COG1028	Short-chain dehydrogenase reductase Sdr
BB2265	COG1960	acyl-CoA dehydrogenase activity
BB2268	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BB2270	COG3468	outer membrane autotransporter barrel domain protein
BB2271	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BB2273	COG0556	nucleotide-excision repair
BB2274	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB2276	COG1104	cysteine desulfurase activity
BB2277	COG0822	iron-sulfur transferase activity
BB2278	COG0316	Belongs to the HesB IscA family
BB2279	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BB2280	COG0443	Heat shock 70 kDa protein
BB2281	COG0633	Ferredoxin
BB2284	COG1024	Enoyl-CoA hydratase
BB2290	COG1022	Amp-dependent synthetase and ligase
BB2293	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BB2294	COG1028	Short-chain dehydrogenase reductase Sdr
BB2295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BB2296	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BB2299	COG1136	(ABC) transporter
BB2300	COG0084	hydrolase, TatD family'
BB2304	COG2333	competence protein COMEC
BB2304	COG0658	competence protein
BB2306	COG0613	PHP domain protein
BB2308	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB2310	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB2311	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BB2311	COG0047	phosphoribosylformylglycinamidine synthase activity
BB2312	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB2312	COG3210	domain, Protein
BB2312	COG3064	Membrane
BB2316	COG3181	Tripartite tricarboxylate transporter family receptor
BB2319	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB2322	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BB2323	COG2197	response regulator
BB2327	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BB2327	COG0519	Catalyzes the synthesis of GMP from XMP
BB2330	COG0477	Major facilitator Superfamily
BB2331	COG2814	Major facilitator Superfamily
BB2332	COG1733	regulation of RNA biosynthetic process
BB2340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BB2343	COG3618	amidohydrolase
BB2345	COG3181	Tripartite tricarboxylate transporter family receptor
BB2350	COG2079	MmgE PrpD family protein
BB2351	COG1012	belongs to the aldehyde dehydrogenase family
BB2358	COG1280	lysine exporter protein (LysE YggA)
BB2361	COG0747	negative chemotaxis
BB2362	COG0601	transmembrane transport
BB2364	COG4172	Belongs to the ABC transporter superfamily
BB2365	COG1609	Transcriptional regulator
BB2367	COG0789	Transcriptional regulator
BB2372	COG2188	Transcriptional regulator
BB2373	COG3181	Tripartite tricarboxylate transporter family receptor
BB2377	COG1802	Transcriptional regulator
BB2380	COG0842	Transport permease protein
BB2381	COG0842	Transport permease protein
BB2382	COG1131	(ABC) transporter
BB2386	COG0656	L-ascorbic acid biosynthetic process
BB2387	COG3284	Transcriptional regulator
BB2388	COG1012	belongs to the aldehyde dehydrogenase family
BB2391	COG2733	membrane
BB2392	COG0583	DNA-binding transcription factor activity
BB2393	COG0384	phenazine biosynthesis protein PhzF
BB2394	COG5507	3-demethylubiquinone-9 3-methyltransferase
BB2395	COG2169	Transcriptional regulator
BB2402	COG0659	secondary active sulfate transmembrane transporter activity
BB2407	COG1132	(ABC) transporter
BB2415	COG2207	Transcriptional regulator
BB2422	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB2423	COG1280	lysine exporter protein (LysE YggA)
BB2427	COG0625	glutathione transferase activity
BB2430	COG0697	spore germination
BB2433	COG0534	Mate efflux family protein
BB2434	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BB2437	COG3246	L-lysine catabolic process to acetate
BB2438	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB2439	COG0583	DNA-binding transcription factor activity
BB2442	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB2443	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB2444	COG3622	Belongs to the hyi family
BB2446	COG0129	dihydroxy-acid dehydratase activity
BB2452	COG0129	dihydroxy-acid dehydratase activity
BB2453	COG3181	Tripartite tricarboxylate transporter family receptor
BB2455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB2458	COG2188	Transcriptional regulator
BB2460	COG0583	DNA-binding transcription factor activity
BB2462	COG0501	Belongs to the peptidase M48B family
BB2464	COG2814	Major facilitator Superfamily
BB2465	COG0583	DNA-binding transcription factor activity
BB2472	COG4691	Plasmid stability protein
BB2478	COG2837	iron assimilation
BB2483	COG1335	isochorismatase
BB2492	COG2963	transposase activity
BB2499	COG2346	COG2346, Truncated hemoglobins
BB2501	COG1126	abc transporter atp-binding protein
BB2503	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB2505	COG0789	Transcriptional regulator
BB2507	COG0165	Argininosuccinate lyase
BB2508	COG0668	transmembrane transport
BB2517	COG0747	negative chemotaxis
BB2518	COG0601	transmembrane transport
BB2520	COG4172	Belongs to the ABC transporter superfamily
BB2521	COG1280	lysine exporter protein (LysE YggA)
BB2522	COG4681	YaeQ
BB2523	COG2814	Major facilitator Superfamily
BB2524	COG3161	chorismate lyase activity
BB2525	COG1187	pseudouridine synthase activity
BB2527	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB2529	COG1538	Outer membrane efflux protein
BB2531	COG1999	signal sequence binding
BB2532	COG0339	signal peptide processing
BB2534	COG4566	intracellular signal transduction
BB2536	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BB2537	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB2538	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB2539	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BB2540	COG1191	sigma factor activity
BB2546	COG0643	Histidine kinase
BB2546	COG2198	Histidine kinase
BB2547	COG0835	chemotaxis
BB2548	COG0840	transmembrane signaling receptor activity
BB2549	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BB2550	COG2201	protein-glutamate methylesterase activity
BB2551	COG0745	RESPONSE REGULATOR receiver
BB2552	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BB2554	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BB2559	COG1815	bacterial-type flagellum-dependent cell motility
BB2560	COG1558	bacterial-type flagellum-dependent cell motility
BB2561	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BB2562	COG1749	Flagellar hook protein flgE
BB2564	COG4786	Flagellar basal body rod
BB2565	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BB2566	COG1706	bacterial-type flagellum-dependent cell motility
BB2568	COG1256	bacterial-type flagellum assembly
BB2570	COG0840	transmembrane signaling receptor activity
BB2574	COG0840	transmembrane signaling receptor activity
BB2575	COG0840	transmembrane signaling receptor activity
BB2578	COG1338	Plays a role in the flagellum-specific transport system
BB2580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BB2582	COG1580	Controls the rotational direction of flagella during chemotaxis
BB2585	COG1157	protein secretion by the type III secretion system
BB2587	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BB2589	COG1677	Flagellar hook-basal body complex protein FliE
BB2591	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BB2597	COG0285	dihydrofolate synthase activity
BB2603	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BB2604	COG0024	Methionine aminopeptidase
BB2605	COG0052	Belongs to the universal ribosomal protein uS2 family
BB2606	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BB2607	COG0528	UMP kinase activity
BB2608	COG0233	cytoplasmic translational termination
BB2609	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BB2611	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BB2612	COG0750	zinc metalloprotease
BB2613	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB2614	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BB2615	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BB2616	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BB2618	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BB2619	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BB2620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB2621	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BB2623	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BB2623	COG0519	Catalyzes the synthesis of GMP from XMP
BB2625	COG0330	HflC and HflK could
BB2626	COG3706	GGDEF domain
BB2627	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BB2628	COG2867	negative regulation of translational initiation
BB2630	COG1960	acyl-CoA dehydrogenase activity
BB2631	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BB2636	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BB2637	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BB2638	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BB2639	COG0084	hydrolase, TatD family'
BB2642	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB2644	COG1126	abc transporter atp-binding protein
BB2645	COG0010	Belongs to the arginase family
BB2646	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB2647	COG1012	belongs to the aldehyde dehydrogenase family
BB2649	COG0028	Belongs to the TPP enzyme family
BB2653	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB2655	COG3189	MarR family transcriptional regulator
BB2657	COG2985	domain, Protein
BB2658	COG0076	glutamate decarboxylase activity
BB2661	COG1595	DNA-templated transcription, initiation
BB2663	COG0861	Integral membrane protein TerC family
BB2668	COG2988	succinylglutamate desuccinylase activity
BB2671	COG1253	flavin adenine dinucleotide binding
BB2673	COG3181	Tripartite tricarboxylate transporter family receptor
BB2674	COG2084	Dehydrogenase
BB2677	COG1619	proteins homologs of microcin C7 resistance protein MccF
BB2680	COG2814	Major facilitator Superfamily
BB2682	COG0583	DNA-binding transcription factor activity
BB2684	COG3181	Tripartite tricarboxylate transporter family receptor
BB2687	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB2688	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BB2689	COG0439	Biotin carboxylase
BB2693	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB2696	COG0395	ABC-type sugar transport system, permease component
BB2697	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB2699	COG3842	ATPase activity
BB2700	COG1414	Transcriptional regulator
BB2701	COG1028	Short-chain dehydrogenase reductase Sdr
BB2703	COG2188	Transcriptional regulator
BB2708	COG3181	Tripartite tricarboxylate transporter family receptor
BB2709	COG0583	DNA-binding transcription factor activity
BB2713	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB2715	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB2717	COG1228	amidohydrolase
BB2723	COG0861	Integral membrane protein TerC family
BB2724	COG1028	Short-chain dehydrogenase reductase Sdr
BB2727	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BB2728	COG0714	Associated with various cellular activities
BB2736	COG3119	arylsulfatase activity
BB2740	COG2197	response regulator
BB2742	COG2944	sequence-specific DNA binding
BB2743	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BB2744	COG0625	glutathione transferase activity
BB2747	COG3119	arylsulfatase activity
BB2749	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB2750	COG1902	pentaerythritol trinitrate reductase activity
BB2752	COG0583	DNA-binding transcription factor activity
BB2756	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB2758	COG0411	ABC transporter
BB2760	COG1309	transcriptional regulator
BB2761	COG1414	Transcriptional regulator
BB2762	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB2763	COG0183	Belongs to the thiolase family
BB2766	COG1028	Short-chain dehydrogenase reductase Sdr
BB2767	COG0583	DNA-binding transcription factor activity
BB2768	COG3181	Tripartite tricarboxylate transporter family receptor
BB2769	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB2770	COG1024	Enoyl-CoA hydratase
BB2772	COG3181	Tripartite tricarboxylate transporter family receptor
BB2773	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB2773	COG1024	Enoyl-CoA hydratase
BB2774	COG0183	Belongs to the thiolase family
BB2775	COG1454	alcohol dehydrogenase
BB2776	COG0824	Thioesterase
BB2780	COG0583	DNA-binding transcription factor activity
BB2781	COG0431	NADPH-dependent FMN reductase
BB2787	COG1028	Short-chain dehydrogenase reductase Sdr
BB2788	COG0583	DNA-binding transcription factor activity
BB2790	COG5001	Diguanylate cyclase
BB2790	COG2203	Gaf domain
BB2790	COG3706	GGDEF domain
BB2790	COG4251	negative regulation of phosphorylation
BB2791	COG1454	alcohol dehydrogenase
BB2791	COG1012	belongs to the aldehyde dehydrogenase family
BB2793	COG0330	HflC and HflK could
BB2796	COG0765	amino acid transport
BB2800	COG0243	molybdopterin cofactor binding
BB2801	COG3043	anaerobic respiration
BB2802	COG3005	denitrification pathway
BB2803	COG4133	protoheme IX ABC transporter activity
BB2807	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BB2809	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB2815	COG4948	Mandelate Racemase Muconate Lactonizing
BB2816	COG3181	Tripartite tricarboxylate transporter family receptor
BB2817	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB2818	COG0066	3-isopropylmalate dehydratase activity
BB2821	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB2823	COG3181	Tripartite tricarboxylate transporter family receptor
BB2825	COG1802	Transcriptional regulator
BB2828	COG0583	DNA-binding transcription factor activity
BB2830	COG3468	outer membrane autotransporter barrel domain protein
BB2832	COG1695	Transcriptional regulator
BB2834	COG3568	Endonuclease Exonuclease Phosphatase
BB2835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB2836	COG0392	lysyltransferase activity
BB2843	COG4575	ribosome binding
BB2844	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BB2846	COG1028	Short-chain dehydrogenase reductase Sdr
BB2856	COG0028	Belongs to the TPP enzyme family
BB2858	COG2204	response regulator
BB2859	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BB2861	COG0297	glycogen (starch) synthase activity
BB2862	COG0366	Alpha amylase catalytic
BB2864	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BB2866	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BB2867	COG1640	4-alpha-glucanotransferase
BB2870	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BB2876	COG0667	Aldo Keto reductase
BB2879	COG2259	Doxx family
BB2883	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB2887	COG0386	Belongs to the glutathione peroxidase family
BB2888	COG0625	glutathione transferase activity
BB2891	COG0095	Lipoate-protein ligase
BB2894	COG0688	phosphatidylethanolamine metabolic process
BB2899	COG2363	Small membrane protein
BB2900	COG0697	spore germination
BB2902	COG2133	pyrroloquinoline quinone binding
BB2903	COG0625	glutathione transferase activity
BB2904	COG1794	racemase activity, acting on amino acids and derivatives
BB2905	COG0410	ABC transporter
BB2908	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB2910	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BB2912	COG1653	transport
BB2913	COG1175	transmembrane transport
BB2914	COG0395	ABC-type sugar transport system, permease component
BB2915	COG3842	ATPase activity
BB2919	COG0156	8-amino-7-oxononanoate synthase activity
BB2921	COG0300	oxidoreductase activity
BB2925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BB2928	COG0438	transferase activity, transferring glycosyl groups
BB2932	COG0463	Glycosyl transferase, family 2
BB2935	COG0783	Belongs to the Dps family
BB2938	COG0583	DNA-binding transcription factor activity
BB2939	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BB2942	COG0656	L-ascorbic acid biosynthetic process
BB2943	COG2814	Major facilitator Superfamily
BB2944	COG0583	DNA-binding transcription factor activity
BB2946	COG1840	ABC-type Fe3 transport system, periplasmic component
BB2947	COG1178	ABC-type Fe3 transport system permease component
BB2948	COG3842	ATPase activity
BB2949	COG1741	Belongs to the pirin family
BB2950	COG1741	Belongs to the pirin family
BB2951	COG0583	DNA-binding transcription factor activity
BB2952	COG2204	response regulator
BB2953	COG3852	Histidine kinase
BB2955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB2956	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BB2957	COG5001	Diguanylate cyclase
BB2957	COG5002	protein histidine kinase activity
BB2958	COG0840	transmembrane signaling receptor activity
BB2961	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BB2962	COG1561	YicC-like family, N-terminal region
BB2966	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BB2967	COG0791	NLP P60 protein
BB2968	COG1028	Short-chain dehydrogenase reductase Sdr
BB2969	COG2863	cytochrome
BB2970	COG3258	Cytochrome c
BB2971	COG0194	GDP metabolic process
BB2972	COG1758	RNA polymerase activity
BB2973	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB2974	COG1126	abc transporter atp-binding protein
BB2975	COG0765	amino acid transport
BB2976	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB2980	COG0583	DNA-binding transcription factor activity
BB2985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB2988	COG2831	hemolysin activation secretion protein
BB2989	COG3539	Fimbrial protein
BB2990	COG3188	usher protein
BB2991	COG3121	Chaperone
BB2993	COG3064	Membrane
BB2993	COG3210	domain, Protein
BB2993	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB2994	COG2197	response regulator
BB2995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB2995	COG2205	protein histidine kinase activity
BB2997	COG4336	lyase activity
BB3000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB3005	COG4181	ATPase activity
BB3007	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB3008	COG0584	glycerophosphoryl diester phosphodiesterase
BB3009	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BB3011	COG0678	peroxiredoxin activity
BB3011	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB3013	COG0789	Transcriptional regulator
BB3014	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BB3019	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BB3020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BB3021	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BB3022	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BB3023	COG2252	PERMEase
BB3024	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB3025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB3031	COG0488	(ABC) transporter
BB3032	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB3034	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB3035	COG1024	Enoyl-CoA hydratase
BB3036	COG1619	proteins homologs of microcin C7 resistance protein MccF
BB3037	COG0590	tRNA wobble adenosine to inosine editing
BB3041	COG2212	antiporter activity
BB3042	COG1863	multisubunit Na H antiporter MnhE subunit
BB3043	COG0651	ATP synthesis coupled electron transport
BB3044	COG1006	Multisubunit Na H antiporter MnhC subunit
BB3045	COG2111	Na H antiporter
BB3045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BB3046	COG3181	Tripartite tricarboxylate transporter family receptor
BB3048	COG0420	3'-5' exonuclease activity
BB3049	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB3055	COG0395	ABC-type sugar transport system, permease component
BB3057	COG3842	ATPase activity
BB3063	COG3181	Tripartite tricarboxylate transporter family receptor
BB3064	COG1053	succinate dehydrogenase
BB3070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB3075	COG0602	queuosine metabolic process
BB3076	COG0720	synthase
BB3077	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB3078	COG0235	Class ii aldolase
BB3083	COG1566	PFAM secretion protein HlyD family protein
BB3085	COG0400	carboxylic ester hydrolase activity
BB3088	COG0587	DNA-directed DNA polymerase activity
BB3089	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB3090	COG1959	2 iron, 2 sulfur cluster binding
BB3091	COG1017	nitric oxide dioxygenase activity
BB3091	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB3098	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB3101	COG0667	Aldo Keto reductase
BB3103	COG5265	(ABC) transporter
BB3110	COG3468	outer membrane autotransporter barrel domain protein
BB3111	COG3468	outer membrane autotransporter barrel domain protein
BB3114	COG5002	protein histidine kinase activity
BB3114	COG3447	MASE1 domain protein
BB3114	COG5001	Diguanylate cyclase
BB3115	COG0840	transmembrane signaling receptor activity
BB3116	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BB3117	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB3120	COG0833	amino acid
BB3126	COG3829	transcription factor binding
BB3128	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BB3132	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB3133	COG1012	belongs to the aldehyde dehydrogenase family
BB3134	COG0028	Belongs to the TPP enzyme family
BB3137	COG0583	DNA-binding transcription factor activity
BB3138	COG4692	amylo-alpha-1,6-glucosidase activity
BB3140	COG0183	Belongs to the thiolase family
BB3143	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB3144	COG0633	Ferredoxin
BB3146	COG1024	Enoyl-CoA hydratase
BB3147	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BB3148	COG4638	Rieske (2fe-2S)
BB3150	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB3160	COG4680	protein conserved in bacteria
BB3161	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB3163	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BB3165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BB3166	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BB3167	COG0330	HflC and HflK could
BB3168	COG0330	HflC and HflK could
BB3169	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BB3170	COG1923	regulation of RNA biosynthetic process
BB3171	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB3172	COG1160	GTP binding
BB3173	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB3174	COG2976	Protein conserved in bacteria
BB3175	COG0124	histidyl-tRNA synthetase
BB3176	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BB3178	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BB3179	COG0105	UTP biosynthetic process
BB3180	COG0525	valine-tRNA ligase activity
BB3182	COG0745	RESPONSE REGULATOR receiver
BB3183	COG0642	Histidine kinase
BB3185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB3186	COG0336	Belongs to the RNA methyltransferase TrmD family
BB3187	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BB3188	COG0228	four-way junction DNA binding
BB3190	COG0425	Belongs to the sulfur carrier protein TusA family
BB3191	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BB3201	COG4172	Belongs to the ABC transporter superfamily
BB3202	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB3203	COG0601	transmembrane transport
BB3204	COG0747	negative chemotaxis
BB3209	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB3211	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BB3214	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BB3215	COG3395	kinase activity
BB3217	COG5285	phytanoyl-CoA dioxygenase
BB3218	COG0662	Cupin 2, conserved barrel domain protein
BB3219	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BB3220	COG0456	acetyltransferase
BB3223	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB3226	COG2311	Membrane
BB3229	COG0187	DNA topoisomerase II activity
BB3231	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BB3233	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BB3234	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BB3235	COG1760	l-serine dehydratase
BB3236	COG1283	sodium-dependent phosphate transmembrane transporter activity
BB3237	COG0412	Dienelactone hydrolase
BB3240	COG1611	Belongs to the LOG family
BB3244	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BB3245	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BB3246	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BB3247	COG2251	uridine kinase activity
BB3247	COG0195	Participates in both transcription termination and antitermination
BB3248	COG0779	Required for maturation of 30S ribosomal subunits
BB3249	COG1187	pseudouridine synthase activity
BB3250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BB3251	COG0583	DNA-binding transcription factor activity
BB3253	COG0523	cobalamin synthesis protein
BB3255	COG0625	glutathione transferase activity
BB3256	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BB3257	COG1047	Peptidyl-prolyl cis-trans
BB3258	COG2003	Belongs to the UPF0758 family
BB3259	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BB3260	COG3483	tryptophan 2,3-dioxygenase activity
BB3261	COG0254	rRNA binding
BB3263	COG0534	Mate efflux family protein
BB3267	COG2304	oxidoreductase activity
BB3270	COG1028	Short-chain dehydrogenase reductase Sdr
BB3271	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB3272	COG1562	ergosterol biosynthetic process
BB3273	COG1562	ergosterol biosynthetic process
BB3274	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BB3274	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BB3275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BB3277	COG0842	Transport permease protein
BB3278	COG1131	(ABC) transporter
BB3282	COG1477	protein flavinylation
BB3285	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BB3288	COG5564	TIM-barrel signal transduction protein
BB3289	COG5441	Belongs to the UPF0261 family
BB3292	COG3468	outer membrane autotransporter barrel domain protein
BB3293	COG0542	response to heat
BB3294	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB3297	COG0494	nUDIX hydrolase
BB3298	COG3530	Putative quorum-sensing-regulated virulence factor
BB3300	COG1595	DNA-templated transcription, initiation
BB3301	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB3307	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB3308	COG0765	amino acid transport
BB3309	COG0765	amino acid transport
BB3314	COG2841	Protein conserved in bacteria
BB3315	COG2814	Major facilitator Superfamily
BB3318	COG0628	permease
BB3319	COG0842	Transport permease protein
BB3320	COG1131	(ABC) transporter
BB3329	COG3278	Belongs to the heme-copper respiratory oxidase family
BB3333	COG0156	8-amino-7-oxononanoate synthase activity
BB3335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BB3335	COG4106	trans-aconitate 2-methyltransferase activity
BB3336	COG1380	Effector of murein hydrolase LrgA
BB3337	COG1346	cytolysis
BB3339	COG2224	Isocitrate lyase
BB3340	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BB3340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BB3342	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BB3343	COG0322	excinuclease ABC activity
BB3344	COG1472	Belongs to the glycosyl hydrolase 3 family
BB3345	COG0736	holo-[acyl-carrier-protein] synthase activity
BB3346	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BB3347	COG1538	Outer membrane efflux protein
BB3348	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB3349	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB3354	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BB3357	COG2032	superoxide dismutase activity
BB3359	COG0318	PFAM AMP-dependent synthetase and ligase
BB3360	COG1024	Enoyl-CoA hydratase
BB3362	COG1802	Transcriptional regulator
BB3364	COG0183	Belongs to the thiolase family
BB3365	COG1942	4-Oxalocrotonate Tautomerase
BB3367	COG4176	ABC-type proline glycine betaine transport system permease component
BB3369	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BB3370	COG2814	Major facilitator Superfamily
BB3371	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BB3372	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BB3375	COG1846	Transcriptional regulator
BB3376	COG2814	Major facilitator Superfamily
BB3377	COG0495	leucyl-tRNA aminoacylation
BB3380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BB3382	COG0154	amidase activity
BB3383	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB3385	COG3012	SEC-C Motif Domain Protein
BB3386	COG1530	ribonuclease E activity
BB3387	COG0077	Prephenate dehydratase
BB3390	COG1132	(ABC) transporter
BB3391	COG0859	PFAM glycosyl transferase family 9
BB3396	COG2194	sulfuric ester hydrolase activity
BB3397	COG0438	transferase activity, transferring glycosyl groups
BB3398	COG0463	Glycosyl transferase, family 2
BB3399	COG0726	polysaccharide deacetylase
BB3400	COG0438	transferase activity, transferring glycosyl groups
BB3403	COG1643	Atp-dependent helicase
BB3405	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BB3407	COG0704	Plays a role in the regulation of phosphate uptake
BB3408	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BB3409	COG1960	acyl-CoA dehydrogenase activity
BB3412	COG2094	Belongs to the DNA glycosylase MPG family
BB3414	COG1177	transmembrane transport
BB3415	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB3416	COG3842	ATPase activity
BB3417	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BB3418	COG3642	lipopolysaccharide core region biosynthetic process
BB3420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BB3421	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB3424	COG3539	Fimbrial protein
BB3425	COG3539	Fimbrial protein
BB3426	COG3539	Fimbrial protein
BB3428	COG2050	protein possibly involved in aromatic compounds catabolism
BB3429	COG1024	Enoyl-CoA hydratase
BB3430	COG1012	belongs to the aldehyde dehydrogenase family
BB3431	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB3432	COG2151	metal-sulfur cluster biosynthetic enzyme
BB3433	COG3396	Phenylacetate-CoA oxygenase
BB3434	COG3460	Phenylacetate-CoA oxygenase
BB3435	COG3396	Phenylacetate-CoA oxygenase
BB3436	COG3327	negative regulation of DNA-templated transcription, initiation
BB3437	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BB3438	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BB3439	COG0501	Belongs to the peptidase M48B family
BB3440	COG1162	GTPase activity
BB3441	COG0667	Aldo Keto reductase
BB3443	COG0335	large ribosomal subunit rRNA binding
BB3449	COG0175	sulfate reduction
BB3450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BB3451	COG4208	sulfate ABC transporter
BB3454	COG0450	alkyl hydroperoxide reductase
BB3455	COG1960	acyl-CoA dehydrogenase activity
BB3458	COG0123	including yeast histone deacetylase and acetoin utilization protein
BB3459	COG2951	lytic endotransglycosylase activity
BB3461	COG1596	polysaccharide export
BB3461	COG1555	photosystem II stabilization
BB3462	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB3463	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BB3464	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BB3468	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BB3469	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BB3470	COG0287	Prephenate dehydrogenase
BB3472	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BB3475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BB3477	COG2814	Major facilitator Superfamily
BB3478	COG2135	peptidase activity
BB3490	COG1196	nuclear chromosome segregation
BB3543	COG0582	viral genome integration into host DNA
BB3544	COG0583	DNA-binding transcription factor activity
BB3552	COG0583	DNA-binding transcription factor activity
BB3555	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB3560	COG1053	succinate dehydrogenase
BB3561	COG1012	belongs to the aldehyde dehydrogenase family
BB3562	COG2079	MmgE PrpD family protein
BB3564	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB3566	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB3567	COG0583	DNA-binding transcription factor activity
BB3569	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BB3569	COG0028	Belongs to the TPP enzyme family
BB3574	COG0778	Nitroreductase
BB3575	COG2814	Major facilitator Superfamily
BB3576	COG3706	GGDEF domain
BB3577	COG0589	response to stress
BB3579	COG2951	lytic endotransglycosylase activity
BB3580	COG2833	Protein of unknown function (DUF455)
BB3583	COG1132	(ABC) transporter
BB3586	COG3237	CsbD-like
BB3588	COG2823	Periplasmic or secreted lipoprotein
BB3594	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BB3595	COG1028	Short-chain dehydrogenase reductase Sdr
BB3596	COG3243	poly(R)-hydroxyalkanoic acid synthase
BB3598	COG0564	pseudouridine synthase activity
BB3600	COG1199	ATP-dependent helicase activity
BB3601	COG2183	response to ionizing radiation
BB3602	COG0180	Tryptophanyl-tRNA synthetase
BB3616	COG4228	DNA circulation
BB3630	COG2369	cell adhesion
BB3632	COG4373	Mu-like prophage FluMu protein gp28
BB3634	COG0640	Transcriptional regulator
BB3653	COG0776	regulation of translation
BB3658	COG4774	siderophore transport
BB3659	COG3712	iron ion homeostasis
BB3660	COG1595	DNA-templated transcription, initiation
BB3661	COG2175	clavaminate synthase activity
BB3663	COG3181	Tripartite tricarboxylate transporter family receptor
BB3664	COG0583	DNA-binding transcription factor activity
BB3665	COG1028	Short-chain dehydrogenase reductase Sdr
BB3666	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BB3667	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB3668	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB3669	COG0567	Dehydrogenase, E1 component
BB3670	COG1297	OPT oligopeptide transporter protein
BB3671	COG1522	sequence-specific DNA binding
BB3673	COG0280	phosphate acetyltransferase
BB3673	COG0281	malic enzyme
BB3674	COG3539	Fimbrial protein
BB3677	COG0372	Belongs to the citrate synthase family
BB3678	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BB3679	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BB3680	COG1053	succinate dehydrogenase
BB3681	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BB3682	COG2009	succinate dehydrogenase
BB3683	COG2188	Transcriptional regulator
BB3684	COG0039	L-malate dehydrogenase activity
BB3688	COG2828	Protein conserved in bacteria
BB3695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB3697	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BB3702	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BB3703	COG0148	phosphopyruvate hydratase activity
BB3705	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BB3706	COG0504	CTP synthase activity
BB3710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB3712	COG0747	negative chemotaxis
BB3713	COG4172	Belongs to the ABC transporter superfamily
BB3714	COG1446	asparaginase
BB3720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BB3723	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BB3724	COG0697	spore germination
BB3725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB3727	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BB3728	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB3729	COG0791	NLP P60 protein
BB3731	COG0583	DNA-binding transcription factor activity
BB3734	COG0583	DNA-binding transcription factor activity
BB3736	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BB3739	COG0670	Belongs to the BI1 family
BB3742	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BB3744	COG1381	Involved in DNA repair and RecF pathway recombination
BB3745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BB3746	COG0571	ribonuclease III activity
BB3747	COG0681	Belongs to the peptidase S26 family
BB3748	COG0481	GTPase activity
BB3749	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB3754	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB3755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB3758	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB3759	COG0416	fatty acid biosynthetic process
BB3760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BB3761	COG1399	metal-binding, possibly nucleic acid-binding protein
BB3762	COG0424	maF-like protein
BB3764	COG3023	N-Acetylmuramoyl-L-alanine amidase
BB3765	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BB3766	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BB3767	COG0546	phosphoglycolate phosphatase activity
BB3769	COG1530	ribonuclease E activity
BB3771	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BB3773	COG0159	tryptophan synthase activity
BB3774	COG0133	tryptophan synthase activity
BB3776	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB3777	COG3228	Belongs to the MtfA family
BB3779	COG0251	oxidation-reduction process
BB3780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BB3781	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BB3784	COG2878	Part of a membrane complex involved in electron transport
BB3785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BB3786	COG0411	ABC transporter
BB3789	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB3792	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB3793	COG0410	ABC transporter
BB3794	COG0411	ABC transporter
BB3797	COG1268	BioY protein
BB3798	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BB3799	COG1122	ATPase activity
BB3800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB3802	COG0271	Belongs to the BolA IbaG family
BB3803	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB3804	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BB3806	COG1196	nuclear chromosome segregation
BB3807	COG0477	Major facilitator Superfamily
BB3808	COG1573	uracil-dna glycosylase
BB3809	COG1214	PFAM Peptidase M22, glycoprotease
BB3810	COG0745	RESPONSE REGULATOR receiver
BB3811	COG2205	protein histidine kinase activity
BB3812	COG0450	alkyl hydroperoxide reductase
BB3813	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB3816	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BB3817	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BB3818	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BB3819	COG0560	Phosphoserine phosphatase
BB3820	COG0583	DNA-binding transcription factor activity
BB3821	COG3181	Tripartite tricarboxylate transporter family receptor
BB3822	COG0028	Belongs to the TPP enzyme family
BB3825	COG4774	siderophore transport
BB3826	COG4774	siderophore transport
BB3828	COG1007	ATP synthesis coupled electron transport
BB3831	COG0713	ATP synthesis coupled electron transport
BB3833	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB3834	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BB3835	COG1034	ATP synthesis coupled electron transport
BB3837	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BB3838	COG0649	NAD binding
BB3839	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB3840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB3841	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB3842	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB3846	COG0671	phosphoesterase, PA-phosphatase related
BB3848	COG1597	lipid kinase activity
BB3849	COG0583	DNA-binding transcription factor activity
BB3850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BB3851	COG1733	regulation of RNA biosynthetic process
BB3852	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB3853	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB3856	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BB3860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB3864	COG3608	succinylglutamate desuccinylase aspartoacylase
BB3865	COG0626	cystathionine gamma-synthase activity
BB3866	COG0583	DNA-binding transcription factor activity
BB3868	COG3181	Tripartite tricarboxylate transporter family receptor
BB3869	COG0165	Argininosuccinate lyase
BB3872	COG3799	methylaspartate ammonia-lyase activity
BB3874	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BB3875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB3876	COG0149	triose-phosphate isomerase activity
BB3879	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB3881	COG1185	polyribonucleotide nucleotidyltransferase activity
BB3882	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BB3884	COG1183	phosphatidylcholine synthase activity
BB3885	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BB3886	COG0440	acetolactate synthase activity
BB3887	COG0028	Belongs to the TPP enzyme family
BB3888	COG1289	transmembrane transporter activity
BB3890	COG3022	response to hydroperoxide
BB3891	COG1028	Short-chain dehydrogenase reductase Sdr
BB3893	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BB3903	COG3706	GGDEF domain
BB3908	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BB3909	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BB3910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BB3911	COG1674	ftsk spoiiie
BB3912	COG0492	ferredoxin-NADP+ reductase activity
BB3913	COG1193	negative regulation of DNA recombination
BB3915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB3917	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BB3918	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BB3919	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BB3920	COG2205	protein histidine kinase activity
BB3921	COG0745	RESPONSE REGULATOR receiver
BB3928	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB3932	COG0612	Peptidase, M16
BB3933	COG0484	heat shock protein binding
BB3934	COG0443	Heat shock 70 kDa protein
BB3936	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BB3938	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BB3939	COG1420	regulation of RNA biosynthetic process
BB3940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BB3941	COG0497	DNA recombination
BB3942	COG0735	belongs to the Fur family
BB3943	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB3944	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BB3945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BB3946	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB3947	COG2030	dehydratase
BB3949	COG1024	Enoyl-CoA hydratase
BB3954	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB3959	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB3960	COG0730	response to heat
BB3962	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB3964	COG0405	Gamma-glutamyltransferase
BB3967	COG1280	lysine exporter protein (LysE YggA)
BB3971	COG0583	DNA-binding transcription factor activity
BB3973	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BB3974	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BB3975	COG0167	dihydroorotate dehydrogenase activity
BB3979	COG1414	Transcriptional regulator
BB3980	COG1546	Belongs to the CinA family
BB3980	COG1058	Belongs to the CinA family
BB3983	COG0513	Belongs to the DEAD box helicase family
BB3989	COG0429	hydrolase of the alpha beta-hydrolase fold
BB3990	COG4783	chaperone-mediated protein folding
BB3993	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB3996	COG0006	proline dipeptidase activity
BB3998	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB4002	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BB4003	COG0632	four-way junction helicase activity
BB4006	COG2255	four-way junction helicase activity
BB4007	COG0514	ATP-dependent DNA helicase (RecQ)
BB4009	COG0745	RESPONSE REGULATOR receiver
BB4012	COG1271	oxidase subunit
BB4013	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB4014	COG0850	regulation of cytokinetic process
BB4015	COG2894	cell division
BB4016	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BB4019	COG0488	(ABC) transporter
BB4024	COG4608	Belongs to the ABC transporter superfamily
BB4025	COG0444	Belongs to the ABC transporter superfamily
BB4026	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB4027	COG0601	transmembrane transport
BB4029	COG1215	transferase activity, transferring glycosyl groups
BB4032	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB4034	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB4037	COG0318	PFAM AMP-dependent synthetase and ligase
BB4038	COG2188	Transcriptional regulator
BB4039	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BB4040	COG2814	Major facilitator Superfamily
BB4042	COG0259	pyridoxamine-phosphate oxidase activity
BB4043	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BB4046	COG0583	DNA-binding transcription factor activity
BB4047	COG1960	acyl-CoA dehydrogenase activity
BB4048	COG3181	Tripartite tricarboxylate transporter family receptor
BB4049	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4050	COG0405	Gamma-glutamyltransferase
BB4052	COG3181	Tripartite tricarboxylate transporter family receptor
BB4054	COG0114	fumarate hydratase activity
BB4055	COG0802	atpase or kinase
BB4056	COG0860	N-Acetylmuramoyl-L-alanine amidase
BB4057	COG0586	Pfam SNARE associated Golgi protein
BB4058	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BB4059	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BB4060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BB4063	COG0617	tRNA 3'-terminal CCA addition
BB4068	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB4069	COG2188	Transcriptional regulator
BB4071	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB4072	COG1234	tRNA 3'-trailer cleavage
BB4073	COG1028	Short-chain dehydrogenase reductase Sdr
BB4075	COG1028	Short-chain dehydrogenase reductase Sdr
BB4076	COG3181	Tripartite tricarboxylate transporter family receptor
BB4077	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB4078	COG2301	Belongs to the HpcH HpaI aldolase family
BB4080	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BB4082	COG1024	Enoyl-CoA hydratase
BB4084	COG2188	Transcriptional regulator
BB4085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB4086	COG0066	3-isopropylmalate dehydratase activity
BB4089	COG0752	glycyl-tRNA synthetase alpha subunit
BB4090	COG0751	glycine-tRNA ligase activity
BB4091	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BB4092	COG0204	Acyl-transferase
BB4095	COG0242	peptide deformylase activity
BB4097	COG0700	Nucleoside recognition
BB4098	COG0469	pyruvate kinase activity
BB4099	COG1929	Belongs to the glycerate kinase type-1 family
BB4100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BB4101	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB4102	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BB4104	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BB4106	COG2154	pterin-4-alpha-carbinolamine dehydratase
BB4110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB4111	COG0154	amidase activity
BB4113	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB4114	COG0601	transmembrane transport
BB4115	COG0747	negative chemotaxis
BB4118	COG0019	diaminopimelate decarboxylase activity
BB4121	COG3712	iron ion homeostasis
BB4122	COG4774	siderophore transport
BB4123	COG2353	YceI-like domain
BB4124	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB4127	COG0583	DNA-binding transcription factor activity
BB4131	COG3384	dioxygenase
BB4132	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB4150	COG1028	Short-chain dehydrogenase reductase Sdr
BB4151	COG1309	transcriptional regulator
BB4152	COG2982	Protein involved in outer membrane biogenesis
BB4153	COG2818	Glycosylase
BB4156	COG1653	transport
BB4157	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB4158	COG3842	ATPase activity
BB4159	COG0395	ABC-type sugar transport system, permease component
BB4160	COG1175	transmembrane transport
BB4163	COG3181	Tripartite tricarboxylate transporter family receptor
BB4164	COG2186	Transcriptional regulator
BB4168	COG1454	alcohol dehydrogenase
BB4170	COG2011	ABC-type metal ion transport system permease component
BB4171	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BB4172	COG1501	Belongs to the glycosyl hydrolase 31 family
BB4173	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB4173	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BB4175	COG0318	PFAM AMP-dependent synthetase and ligase
BB4176	COG1473	amidohydrolase
BB4178	COG2855	membrane
BB4179	COG1607	acyl-coa hydrolase
BB4180	COG2239	Acts as a magnesium transporter
BB4183	COG1522	sequence-specific DNA binding
BB4184	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB4185	COG1028	Short-chain dehydrogenase reductase Sdr
BB4189	COG0653	protein targeting
BB4190	COG0739	heme binding
BB4192	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BB4193	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BB4195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BB4196	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB4197	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BB4198	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BB4200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BB4201	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB4202	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BB4204	COG3116	cell division
BB4205	COG0275	rRNA processing
BB4206	COG2001	Belongs to the MraZ family
BB4208	COG0418	dihydroorotase activity
BB4209	COG1473	amidohydrolase
BB4212	COG1522	sequence-specific DNA binding
BB4214	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB4215	COG4654	Cytochrome c, class I
BB4216	COG0129	dihydroxy-acid dehydratase activity
BB4217	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BB4224	COG2084	Dehydrogenase
BB4225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BB4231	COG0494	nUDIX hydrolase
BB4232	COG0442	prolyl-tRNA aminoacylation
BB4233	COG0824	Thioesterase
BB4234	COG0811	peptide transport
BB4235	COG0848	biopolymer transport protein
BB4237	COG0823	Involved in the tonB-independent uptake of proteins
BB4240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB4241	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BB4242	COG3181	Tripartite tricarboxylate transporter family receptor
BB4244	COG1846	Transcriptional regulator
BB4245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB4250	COG0183	Belongs to the thiolase family
BB4252	COG1960	acyl-CoA dehydrogenase activity
BB4253	COG0583	DNA-binding transcription factor activity
BB4254	COG3181	Tripartite tricarboxylate transporter family receptor
BB4255	COG1024	Enoyl-CoA hydratase
BB4256	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4257	COG1253	flavin adenine dinucleotide binding
BB4258	COG1285	pathogenesis
BB4259	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BB4262	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB4263	COG0697	spore germination
BB4268	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BB4269	COG0463	Glycosyl transferase, family 2
BB4271	COG0786	glutamate:sodium symporter activity
BB4273	COG2031	fatty acid transporter
BB4275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB4276	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB4277	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB4278	COG0328	RNA-DNA hybrid ribonuclease activity
BB4279	COG2226	methyltransferase
BB4281	COG0741	lytic transglycosylase activity
BB4281	COG1388	LysM domain
BB4284	COG2979	Protein of unknown function (DUF533)
BB4292	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB4301	COG2816	NAD+ diphosphatase activity
BB4302	COG1309	transcriptional regulator
BB4303	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4306	COG1024	Enoyl-CoA hydratase
BB4309	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB4312	COG3181	Tripartite tricarboxylate transporter family receptor
BB4315	COG3119	arylsulfatase activity
BB4320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BB4321	COG0830	nickel cation binding
BB4322	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BB4323	COG0804	urea catabolic process
BB4324	COG0832	Belongs to the urease beta subunit family
BB4326	COG0831	urea catabolic process
BB4327	COG0829	nickel cation binding
BB4328	COG0583	DNA-binding transcription factor activity
BB4329	COG3181	Tripartite tricarboxylate transporter family receptor
BB4334	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4336	COG2188	Transcriptional regulator
BB4341	COG2719	SpoVR family
BB4342	COG2718	Belongs to the UPF0229 family
BB4343	COG2766	serine protein kinase
BB4344	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BB4344	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BB4346	COG4977	sequence-specific DNA binding
BB4347	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BB4348	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB4350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BB4352	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BB4353	COG0316	Belongs to the HesB IscA family
BB4355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BB4356	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BB4357	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BB4358	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB4359	COG0312	modulator of DNA gyrase
BB4363	COG1116	anion transmembrane transporter activity
BB4364	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB4365	COG1335	isochorismatase
BB4366	COG0346	lactoylglutathione lyase activity
BB4367	COG0513	Belongs to the DEAD box helicase family
BB4368	COG3069	C4-dicarboxylate transmembrane transporter activity
BB4369	COG1802	Transcriptional regulator
BB4370	COG0045	succinate-CoA ligase (ADP-forming) activity
BB4370	COG1042	CoA-binding domain protein
BB4370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB4371	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB4374	COG1522	sequence-specific DNA binding
BB4380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BB4381	COG1696	Membrane protein involved in D-alanine export
BB4388	COG2264	protein methyltransferase activity
BB4389	COG0439	Biotin carboxylase
BB4390	COG0511	ligase activity, forming carbon-carbon bonds
BB4391	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BB4392	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB4393	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BB4394	COG3150	esterase
BB4395	COG0557	exoribonuclease II activity
BB4397	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BB4398	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB4400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB4403	COG0540	Belongs to the ATCase OTCase family
BB4404	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BB4405	COG1678	Uncharacterized ACR, COG1678
BB4408	COG0352	thiamine-phosphate diphosphorylase activity
BB4409	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BB4415	COG1024	Enoyl-CoA hydratase
BB4416	COG1028	Short-chain dehydrogenase reductase Sdr
BB4418	COG0410	ABC transporter
BB4419	COG0411	ABC transporter
BB4421	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB4426	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BB4428	COG0494	nUDIX hydrolase
BB4429	COG1538	Outer membrane efflux protein
BB4433	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BB4434	COG0237	dephospho-CoA kinase activity
BB4435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BB4438	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BB4439	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BB4441	COG0477	Major facilitator Superfamily
BB4442	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BB4445	COG1126	abc transporter atp-binding protein
BB4446	COG0765	amino acid transport
BB4447	COG4597	amino acid ABC transporter
BB4448	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB4449	COG2884	Cell division ATP-binding protein ftsE
BB4450	COG2177	Part of the ABC transporter FtsEX involved in
BB4451	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BB4453	COG1194	a g-specific adenine glycosylase
BB4455	COG2226	methyltransferase
BB4457	COG4206	TonB-dependent receptor
BB4458	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BB4459	COG2022	thiamine diphosphate biosynthetic process
BB4460	COG0351	phosphomethylpyrimidine kinase
BB4461	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BB4463	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BB4465	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BB4468	COG2226	methyltransferase
BB4469	COG0745	RESPONSE REGULATOR receiver
BB4470	COG5002	protein histidine kinase activity
BB4472	COG5002	protein histidine kinase activity
BB4474	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB4475	COG0583	DNA-binding transcription factor activity
BB4477	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BB4478	COG1984	allophanate hydrolase subunit 2
BB4479	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BB4481	COG3181	Tripartite tricarboxylate transporter family receptor
BB4483	COG1024	Enoyl-CoA hydratase
BB4484	COG0657	acetylesterase activity
BB4486	COG1802	Transcriptional regulator
BB4488	COG1238	metal cluster binding
BB4489	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB4490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB4493	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BB4494	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BB4495	COG4988	ABC transporter
BB4497	COG1294	oxidase, subunit
BB4500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BB4502	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BB4505	COG1137	ATPase activity
BB4506	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BB4508	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BB4509	COG2010	Cytochrome c
BB4509	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BB4513	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB4515	COG0792	nuclease activity
BB4516	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BB4517	COG2823	Periplasmic or secreted lipoprotein
BB4520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BB4522	COG1309	transcriptional regulator
BB4523	COG0471	metal ion transport
BB4524	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BB4525	COG0772	Belongs to the SEDS family
BB4526	COG0768	penicillin binding
BB4528	COG1792	Involved in formation and maintenance of cell shape
BB4529	COG1077	Cell shape determining protein MreB Mrl
BB4530	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BB4531	COG0154	amidase activity
BB4532	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BB4533	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BB4534	COG0708	Exodeoxyribonuclease III
BB4535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB4536	COG2860	membrane
BB4538	COG0583	DNA-binding transcription factor activity
BB4539	COG0473	3-isopropylmalate dehydrogenase activity
BB4540	COG3391	amine dehydrogenase activity
BB4544	COG0583	DNA-binding transcription factor activity
BB4545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BB4546	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB4547	COG0765	amino acid transport
BB4548	COG0765	amino acid transport
BB4549	COG1126	abc transporter atp-binding protein
BB4550	COG1794	racemase activity, acting on amino acids and derivatives
BB4551	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB4552	COG2223	nitrite transmembrane transporter activity
BB4553	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB4553	COG2813	Specifically methylates the guanine in position
BB4554	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB4555	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BB4560	COG2918	glutathione biosynthetic process
BB4564	COG0583	DNA-binding transcription factor activity
BB4565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BB4566	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB4568	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB4576	COG1414	Transcriptional regulator
BB4580	COG2132	Multicopper oxidase
BB4583	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB4588	COG1024	Enoyl-CoA hydratase
BB4589	COG1024	Enoyl-CoA hydratase
BB4590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BB4592	COG0747	negative chemotaxis
BB4594	COG0601	transmembrane transport
BB4595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB4596	COG0444	Belongs to the ABC transporter superfamily
BB4597	COG4608	Belongs to the ABC transporter superfamily
BB4599	COG2195	Cleaves the N-terminal amino acid of tripeptides
BB4600	COG0210	DNA helicase
BB4601	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BB4602	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BB4604	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BB4605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BB4606	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BB4607	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BB4608	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BB4609	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BB4611	COG0356	it plays a direct role in the translocation of protons across the membrane
BB4614	COG1024	Enoyl-CoA hydratase
BB4618	COG0037	tRNA processing
BB4619	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB4620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BB4621	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB4622	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BB4623	COG2967	ApaG domain
BB4625	COG0546	phosphoglycolate phosphatase activity
BB4627	COG0512	Glutamine amidotransferase of anthranilate synthase
BB4628	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BB4629	COG0134	indole-3-glycerol-phosphate synthase activity
BB4630	COG1028	Short-chain dehydrogenase reductase Sdr
BB4634	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BB4636	COG1607	acyl-coa hydrolase
BB4645	COG3069	C4-dicarboxylate transmembrane transporter activity
BB4647	COG1802	Transcriptional regulator
BB4653	COG1595	DNA-templated transcription, initiation
BB4654	COG3712	iron ion homeostasis
BB4656	COG3720	iron ion transport
BB4657	COG4558	Periplasmic binding protein
BB4658	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB4659	COG1120	ATPase activity
BB4660	COG1683	Conserved Protein
BB4663	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB4666	COG3064	Membrane
BB4667	COG0583	DNA-binding transcription factor activity
BB4669	COG1234	tRNA 3'-trailer cleavage
BB4671	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BB4672	COG1802	Transcriptional regulator
BB4674	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB4675	COG3181	Tripartite tricarboxylate transporter family receptor
BB4678	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4682	COG3181	Tripartite tricarboxylate transporter family receptor
BB4685	COG2186	Transcriptional regulator
BB4686	COG1028	Short-chain dehydrogenase reductase Sdr
BB4687	COG4948	Mandelate Racemase Muconate Lactonizing
BB4692	COG3181	Tripartite tricarboxylate transporter family receptor
BB4695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB4696	COG0410	ABC transporter
BB4697	COG0411	ABC transporter
BB4698	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB4699	COG0683	leucine binding
BB4703	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB4704	COG1024	Enoyl-CoA hydratase
BB4704A	COG0022	dehydrogenase e1 component
BB4705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BB4710	COG1960	acyl-CoA dehydrogenase activity
BB4711	COG1024	Enoyl-CoA hydratase
BB4712	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB4716	COG1960	acyl-CoA dehydrogenase activity
BB4717	COG3181	Tripartite tricarboxylate transporter family receptor
BB4718	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB4723	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BB4724	COG1984	allophanate hydrolase subunit 2
BB4725	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BB4726	COG0747	negative chemotaxis
BB4727	COG0601	transmembrane transport
BB4728	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB4729	COG4172	Belongs to the ABC transporter superfamily
BB4734	COG0511	ligase activity, forming carbon-carbon bonds
BB4735	COG0439	Biotin carboxylase
BB4738	COG0709	Synthesizes selenophosphate from selenide and ATP
BB4739	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BB4746	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4748	COG0604	alcohol dehydrogenase
BB4750	COG1028	Short-chain dehydrogenase reductase Sdr
BB4752	COG1960	acyl-CoA dehydrogenase activity
BB4753	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4754	COG3181	Tripartite tricarboxylate transporter family receptor
BB4755	COG1024	Enoyl-CoA hydratase
BB4756	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB4756	COG1902	pentaerythritol trinitrate reductase activity
BB4757	COG1024	Enoyl-CoA hydratase
BB4758	COG1846	Transcriptional regulator
BB4761	COG4771	TonB-dependent receptor
BB4764	COG1028	Short-chain dehydrogenase reductase Sdr
BB4765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4766	COG0183	Belongs to the thiolase family
BB4767	COG2030	dehydratase
BB4768	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4776	COG3842	ATPase activity
BB4778	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BB4780	COG1028	Short-chain dehydrogenase reductase Sdr
BB4781	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BB4782	COG0583	DNA-binding transcription factor activity
BB4785	COG3181	Tripartite tricarboxylate transporter family receptor
BB4787	COG0277	FAD linked oxidase domain protein
BB4788	COG1960	acyl-CoA dehydrogenase activity
BB4789	COG1960	acyl-CoA dehydrogenase activity
BB4791	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB4794	COG2072	flavoprotein involved in K transport
BB4795	COG0604	alcohol dehydrogenase
BB4798	COG1024	Enoyl-CoA hydratase
BB4800	COG3181	Tripartite tricarboxylate transporter family receptor
BB4802	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BB4803	COG1522	sequence-specific DNA binding
BB4804	COG0183	Belongs to the thiolase family
BB4806	COG1960	acyl-CoA dehydrogenase activity
BB4813	COG3708	Transcriptional regulator
BB4813	COG2207	Transcriptional regulator
BB4816	COG2814	Major facilitator Superfamily
BB4817	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BB4821	COG1999	signal sequence binding
BB4822	COG0109	protoheme IX farnesyltransferase activity
BB4830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB4834	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BB4835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB4837	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BB4838	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BB4840	COG0070	glutamate synthase
BB4840	COG0069	glutamate synthase activity
BB4840	COG0067	glutamate synthase
BB4842	COG3047	cAMP biosynthetic process
BB4844	COG1127	ABC transporter
BB4845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BB4846	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BB4847	COG2853	Lipoprotein
BB4849	COG1131	(ABC) transporter
BB4850	COG0842	Transport permease protein
BB4852	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB4853	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BB4854	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BB4855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB4856	COG0131	Imidazoleglycerol-phosphate dehydratase
BB4857	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BB4858	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BB4859	COG0107	imidazoleglycerol-phosphate synthase activity
BB4860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BB4861	COG0140	phosphoribosyl-ATP diphosphatase activity
BB4862	COG0537	adenosine 5'-monophosphoramidase activity
BB4863	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB4864	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB4868	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BB4869	COG1970	mechanosensitive ion channel activity
BB4870	COG0723	plastoquinol--plastocyanin reductase activity
BB4871	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BB4872	COG2857	Cytochrome c1
BB4873	COG0625	glutathione transferase activity
BB4874	COG2969	positive regulation of protein catabolic process
BB4879	COG0583	DNA-binding transcription factor activity
BB4880	COG0492	ferredoxin-NADP+ reductase activity
BB4884	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4886	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB4889	COG3181	Tripartite tricarboxylate transporter family receptor
BB4896	COG3702	type iv secretory pathway
BB4897	COG3451	type IV secretory pathway VirB4
BB4899	COG3736	Type IV secretory pathway, component VirB8
BB4900	COG3504	Conjugal transfer protein
BB4901	COG2948	multi-organism process
BB4902	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BB4903	COG0697	spore germination
BB4907	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BB4908	COG0747	negative chemotaxis
BB4910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB4912	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BB4914	COG0513	Belongs to the DEAD box helicase family
BB4915	COG1280	lysine exporter protein (LysE YggA)
BB4916	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BB4920	COG0583	DNA-binding transcription factor activity
BB4922	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BB4924	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB4925	COG0154	amidase activity
BB4926	COG1609	Transcriptional regulator
BB4930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BB4931	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BB4932	COG3842	ATPase activity
BB4933	COG1653	transport
BB4934	COG1175	transmembrane transport
BB4935	COG0395	ABC-type sugar transport system, permease component
BB4938	COG0018	arginyl-trna synthetase
BB4940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BB4942	COG1280	lysine exporter protein (LysE YggA)
BB4945	COG1960	acyl-CoA dehydrogenase activity
BB4946	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BB4947	COG0183	Belongs to the thiolase family
BB4948	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB4951	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB4952	COG3181	Tripartite tricarboxylate transporter family receptor
BB4956	COG1629	transport
BB4957	COG2922	Belongs to the Smg family
BB4958	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB4962	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB4963	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB4964	COG1028	Short-chain dehydrogenase reductase Sdr
BB4965	COG1012	belongs to the aldehyde dehydrogenase family
BB4967	COG0028	Belongs to the TPP enzyme family
BB4968	COG1522	sequence-specific DNA binding
BB4969	COG3781	membrane
BB4971	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BB4975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BB4980	COG1304	FMN binding
BB4981	COG1254	Belongs to the acylphosphatase family
BB4983	COG0154	amidase activity
BB4984	COG1414	Transcriptional regulator
BB4989	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BB4990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BB4991	COG0594	ribonuclease P activity
BB4992	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BB4993	COG0706	membrane insertase activity
BB4994	COG0753	catalase activity
BB4995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB4996	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB4998	COG2175	clavaminate synthase activity
BB4999	COG1473	amidohydrolase
BB5000	COG4608	Belongs to the ABC transporter superfamily
BB5001	COG0444	Belongs to the ABC transporter superfamily
BB5003	COG0601	transmembrane transport
BB5004	COG0747	negative chemotaxis
BB5005	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BB5008	COG5002	protein histidine kinase activity
BB5008	COG3850	Histidine kinase
BB5012	COG0436	Aminotransferase
BB5013	COG1278	Cold shock