locus-tag	class	description
BTL48_00005	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BTL48_00010	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BTL48_00015	ENOG4107QJE	Chromosome Partitioning Protein
BTL48_00020	ENOG4105FA0	parb-like partition protein
BTL48_00025	ENOG4105HDK	L-asparaginase
BTL48_00045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BTL48_00055	ENOG410683Z	Preprotein translocase SecE subunit
BTL48_00065	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BTL48_00070	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BTL48_00075	ENOG4108VZM	50s ribosomal protein L10
BTL48_00080	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BTL48_00085	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BTL48_00090	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BTL48_00125	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BTL48_00130	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BTL48_00135	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BTL48_00140	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BTL48_00145	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BTL48_00150	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BTL48_00155	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BTL48_00160	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BTL48_00165	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BTL48_00170	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BTL48_00175	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BTL48_00180	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BTL48_00185	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BTL48_00190	ENOG41084PQ	50s ribosomal protein l29
BTL48_00195	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BTL48_00210	ENOG4108IV0	ABC, transporter
BTL48_00215	ENOG4105C2J	ABC transporter
BTL48_00220	ENOG4105C0Z	ABC transporter
BTL48_00250	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BTL48_00255	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BTL48_00260	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BTL48_00265	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BTL48_00270	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BTL48_00275	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BTL48_00280	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BTL48_00285	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BTL48_00290	ENOG4105VPB	50S ribosomal protein L30
BTL48_00295	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BTL48_00300	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BTL48_00305	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BTL48_00315	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTL48_00320	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BTL48_00325	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BTL48_00330	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BTL48_00335	ENOG4108ZT0	50S ribosomal protein l17
BTL48_00340	ENOG4107YU2	histidine triad (hIT) protein
BTL48_00345	ENOG4105VF7	tolerance protein
BTL48_00350	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BTL48_00360	ENOG4105D52	delta-aminolevulinic acid dehydratase
BTL48_00365	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BTL48_00370	ENOG4106RE7	Cytochrome
BTL48_00375	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
BTL48_00380	ENOG4105CRE	cytochrome C
BTL48_00385	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BTL48_00395	ENOG4105XQ6	frataxin-like protein
BTL48_00400	ENOG4108JQC	penicillin-binding protein 1A
BTL48_00405	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BTL48_00410	ENOG4105D49	3-dehydroquinate synthase
BTL48_00415	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BTL48_00435	ENOG4107RDB	Major Facilitator
BTL48_00450	ENOG4105CMM	transposase
BTL48_00495	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BTL48_00500	ENOG4108RPN	Protein smg homolog
BTL48_00525	ENOG4105C8Y	Acetylornithine aminotransferase
BTL48_00540	ENOG4107QX3	carboxylase
BTL48_00545	ENOG4105CHU	acetyl-coa acetyltransferase
BTL48_00550	ENOG4105C1G	acyl-Coa dehydrogenase
BTL48_00575	ENOG4105CXC	rtn protein
BTL48_00580	ENOG4108Z33	Thiol disulfide Interchange Protein
BTL48_00590	ENOG4105C75	arginyL-tRNA synthetase
BTL48_00605	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BTL48_00610	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BTL48_00620	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BTL48_00630	ENOG4107RT3	EamA-like transporter family
BTL48_00635	ENOG4108UQY	Iron-storage protein
BTL48_00645	ENOG4105C26	Dehydrogenase
BTL48_00660	ENOG4105VG1	fes assembly suf system protein
BTL48_00715	ENOG4108K3A	Glutathione S-transferase
BTL48_00720	ENOG4108WUH	Transcriptional regulator, TetR family
BTL48_00750	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BTL48_00755	ENOG410829K	Lysine exporter protein (Lyse ygga)
BTL48_00760	ENOG4105C1J	atp-dependent rna helicase
BTL48_00770	ENOG4105HA9	of methanol dehydrogenase type
BTL48_00775	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BTL48_00780	ENOG4105KD1	integral membrane protein
BTL48_00805	ENOG4105KB2	stringent starvation protein b
BTL48_00810	ENOG4107MKT	Stringent starvation protein a
BTL48_00815	ENOG4105EIX	cytochrome c1
BTL48_00820	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BTL48_00825	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BTL48_00830	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BTL48_00835	ENOG4107QNR	UPF0135 protein
BTL48_00840	ENOG4105C0H	protease
BTL48_00850	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BTL48_00855	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BTL48_00860	ENOG4105K59	histidine triad (HIT) protein
BTL48_00865	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
BTL48_00870	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BTL48_00875	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BTL48_00880	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BTL48_00885	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BTL48_00890	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BTL48_00895	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BTL48_00900	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BTL48_00905	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BTL48_00910	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BTL48_00920	ENOG4105E3A	(ABC) transporter
BTL48_00925	ENOG4105DA5	(ABC) transporter
BTL48_00935	ENOG410903C	(LipO)protein
BTL48_00940	ENOG4107PE3	Mammalian cell entry related domain protein
BTL48_00945	ENOG4105CY3	ABC transporter, permease
BTL48_00950	ENOG4105DHJ	ABC, transporter
BTL48_00960	ENOG4105EIF	outer membrane protein W
BTL48_00985	ENOG4107QPD	alcohol dehydrogenase
BTL48_00990	ENOG4105C4W	S-formylglutathione hydrolase
BTL48_01010	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BTL48_01015	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
BTL48_01025	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
BTL48_01035	ENOG4105CMM	transposase
BTL48_01040	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
BTL48_01055	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BTL48_01065	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
BTL48_01090	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BTL48_01115	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BTL48_01120	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BTL48_01125	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BTL48_01140	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BTL48_01180	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BTL48_01185	ENOG4105CXK	mandelate racemase muconate lactonizing
BTL48_01195	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
BTL48_01200	ENOG4105CBG	Sulfatase
BTL48_01220	ENOG4105CMM	transposase
BTL48_01240	ENOG4105DZC	cytosine deaminase
BTL48_01245	ENOG4108T2C	cysteine dioxygenase type I
BTL48_01250	ENOG4105DMF	Dehydrogenase
BTL48_01255	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
BTL48_01260	ENOG4108IG5	Transcriptional regulator
BTL48_01275	ENOG4108FUF	Transcriptional regulator, IclR family
BTL48_01285	ENOG4105CMM	transposase
BTL48_01300	ENOG4105F5H	Glycosyl Hydrolase Family 88
BTL48_01305	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BTL48_01310	ENOG4105C1G	acyl-Coa dehydrogenase
BTL48_01325	ENOG4108IG5	Transcriptional regulator
BTL48_01335	ENOG4108Z8I	decarboxylase
BTL48_01340	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BTL48_01350	ENOG4105DDW	LysR family Transcriptional regulator
BTL48_01365	ENOG4105C01	Dihydroxy-acid dehydratase
BTL48_01370	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BTL48_01385	ENOG4108UPT	UPF0178 protein
BTL48_01390	ENOG4108Z9W	Outer membrane porin
BTL48_01400	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BTL48_01405	ENOG4105R8A	Heat shock protein
BTL48_01410	ENOG4105BZU	Histidine kinase
BTL48_01430	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BTL48_01435	ENOG4105CF1	Alkylated DNA repair protein
BTL48_01445	ENOG4105EWC	Purine nucleoside phosphorylase
BTL48_01450	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
BTL48_01465	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
BTL48_01470	ENOG4105EHG	Permease protein
BTL48_01475	ENOG4107R4I	Periplasmic binding protein
BTL48_01480	ENOG4106QJH	hemin transport protein
BTL48_01490	ENOG4108S3W	Anti-feci sigma factor, fecr
BTL48_01495	ENOG4108SF5	RNA Polymerase
BTL48_01525	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BTL48_01530	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BTL48_01535	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
BTL48_01540	ENOG4108MG3	formate dehydrogenase
BTL48_01545	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
BTL48_01555	ENOG4105EM7	Selenocysteine-specific translation elongation factor
BTL48_01585	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BTL48_01590	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BTL48_01595	ENOG4105DDQ	anthranilate synthase
BTL48_01605	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BTL48_01610	ENOG4105DJV	ribulose-phosphate 3-epimerase
BTL48_01615	ENOG4105NWN	ApaG protein
BTL48_01620	ENOG4105CA3	membrane-bound lytic murein transglycosylase
BTL48_01625	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BTL48_01630	ENOG4105T95	Thiol disulfide interChange protein
BTL48_01640	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BTL48_01660	ENOG4105E39	Enoyl-CoA hydratase
BTL48_01675	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
BTL48_01680	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BTL48_01685	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BTL48_01690	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BTL48_01695	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BTL48_01700	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BTL48_01705	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BTL48_01710	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BTL48_01735	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BTL48_01740	ENOG4105C25	Primosomal protein n'
BTL48_01745	ENOG4105C4R	Atp-dependent dna helicase
BTL48_01750	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BTL48_01760	ENOG4108JQ7	(ABC) transporter
BTL48_01765	ENOG4105C3U	ABC transporter
BTL48_01770	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BTL48_01795	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BTL48_01800	ENOG41060WC	Enoyl-CoA hydratase
BTL48_01805	ENOG4108UKI	Enoyl-CoA hydratase
BTL48_01810	ENOG4105EA8	2-Nitropropane dioxygenase
BTL48_01825	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BTL48_01830	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BTL48_01845	ENOG4105D9M	gamma-glutamylcysteine synthetase
BTL48_01850	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
BTL48_01870	ENOG4105DG4	malate L-lactate dehydrogenase
BTL48_01875	ENOG4105DWV	Homoserine O-trans-acetylase
BTL48_01880	ENOG4105DWV	Homoserine O-trans-acetylase
BTL48_01885	ENOG4105EYM	Major Facilitator superfamily
BTL48_01890	ENOG4108Z9W	Outer membrane porin
BTL48_01905	ENOG4105D82	Glutamate dehydrogenase
BTL48_01910	ENOG4105CGK	Exodeoxyribonuclease III
BTL48_01915	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BTL48_01920	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BTL48_01925	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BTL48_01930	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BTL48_01935	ENOG4105DFF	Rod shape-determining protein mreb
BTL48_01940	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BTL48_01950	ENOG4105CJN	penicillin-binding protein
BTL48_01955	ENOG4105CNI	cell division protein FtsW
BTL48_01960	ENOG4105DG4	malate L-lactate dehydrogenase
BTL48_01965	ENOG4107QPK	)-transporter
BTL48_01970	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
BTL48_01980	ENOG4105CAS	nag kinase
BTL48_01985	ENOG4105D01	(LipO)protein
BTL48_01995	ENOG4105W4M	Transport-associated protein
BTL48_02000	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
BTL48_02005	ENOG41082FP	UPF0102 protein
BTL48_02025	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BTL48_02040	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BTL48_02045	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
BTL48_02050	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
BTL48_02065	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
BTL48_02070	ENOG4108IUZ	ABC transporter
BTL48_02090	ENOG4105C2X	Arabinose 5-phosphate isomerase
BTL48_02095	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
BTL48_02100	ENOG4105E0K	tonB-dependent siderophore receptor
BTL48_02110	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BTL48_02115	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BTL48_02125	ENOG4108JJ9	ABC, transporter
BTL48_02130	ENOG4108JJ8	(ABC) transporter
BTL48_02135	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BTL48_02140	ENOG4105EXG	Transcriptional regulator
BTL48_02150	ENOG4105C7B	Threonine dehydratase
BTL48_02155	ENOG4105W39	Membrane
BTL48_02170	ENOG4105E7W	lamb ycsf family protein
BTL48_02180	ENOG4105P4J	Allophanate hydrolase, subunit 1
BTL48_02190	ENOG4107RSM	transcriptional regulator
BTL48_02195	ENOG4108JQ1	Dehydrogenase
BTL48_02200	ENOG4105BZU	Histidine kinase
BTL48_02205	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BTL48_02210	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BTL48_02245	ENOG4108P1X	synthase
BTL48_02275	ENOG4105D3Q	Sugar transferase
BTL48_02280	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BTL48_02290	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BTL48_02315	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
BTL48_02320	ENOG4105DFG	type I secretion outer membrane protein
BTL48_02325	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BTL48_02330	ENOG4105DWF	phosphomethylpyrimidine kinase
BTL48_02335	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BTL48_02340	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
BTL48_02355	ENOG4105C3R	Methionine synthase
BTL48_02360	ENOG4105F2W	methyltransferase
BTL48_02370	ENOG4105CEN	a g-specific adenine glycosylase
BTL48_02380	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BTL48_02385	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BTL48_02390	ENOG4105CAK	Cell division ATP-binding protein ftsE
BTL48_02395	ENOG4107QXX	ABC transporter
BTL48_02400	ENOG4105EZ7	amino acid ABC transporter
BTL48_02405	ENOG4105DRP	amino acid AbC transporter
BTL48_02410	ENOG4105CDA	abc transporter atp-binding protein
BTL48_02425	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BTL48_02440	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BTL48_02450	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BTL48_02455	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BTL48_02470	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BTL48_02475	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BTL48_02480	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
BTL48_02490	ENOG4105BZS	acriflavin resistance protein
BTL48_02495	ENOG4105BZS	acriflavin resistance protein
BTL48_02500	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BTL48_02505	ENOG4105X0I	Fimbrial
BTL48_02525	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BTL48_02535	ENOG410834F	Transcriptional regulator
BTL48_02550	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_02555	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BTL48_02560	ENOG4105C0Z	ABC transporter
BTL48_02565	ENOG4108IV0	ABC, transporter
BTL48_02590	ENOG4105BZU	Histidine kinase
BTL48_02600	ENOG4105DTD	Dehydrogenase
BTL48_02605	ENOG4108UKI	Enoyl-CoA hydratase
BTL48_02610	ENOG4105C1G	acyl-Coa dehydrogenase
BTL48_02640	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BTL48_02645	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BTL48_02650	ENOG4105DWF	phosphomethylpyrimidine kinase
BTL48_02655	ENOG4105VCQ	rubredoxin
BTL48_02660	ENOG4108UJU	UPF0301 protein
BTL48_02665	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BTL48_02685	ENOG4108Z20	Acyl-transferase
BTL48_02690	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BTL48_02700	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
BTL48_02705	ENOG4105E2X	shikimate dehydrogenase
BTL48_02725	ENOG4105DFU	Cell wall formation (By similarity)
BTL48_02730	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTL48_02735	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BTL48_02740	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BTL48_02745	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BTL48_02750	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BTL48_02780	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
BTL48_02785	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
BTL48_02800	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BTL48_02805	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BTL48_02825	ENOG4108YXU	transcriptional regulator AsnC family
BTL48_02840	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BTL48_02845	ENOG4105CD5	CoA-binding domain protein
BTL48_02850	ENOG4108IV0	ABC, transporter
BTL48_02855	ENOG4105C0Z	ABC transporter
BTL48_02860	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BTL48_02870	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_02900	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BTL48_02925	ENOG4105N42	UPF0307 protein
BTL48_02930	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BTL48_02935	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BTL48_02940	ENOG4108UJD	30S ribosomal protein S9
BTL48_02945	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BTL48_02955	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BTL48_02965	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BTL48_02975	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BTL48_02980	ENOG4108V1U	phospholipid-binding protein
BTL48_02985	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BTL48_02990	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BTL48_03005	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BTL48_03020	ENOG4106AKX	UPF0229 protein
BTL48_03025	ENOG4105ED1	spovr family
BTL48_03040	ENOG4108KB2	LysR family Transcriptional regulator
BTL48_03055	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
BTL48_03070	ENOG4105CSH	Transporter
BTL48_03085	ENOG4105CH7	arginosuccinase
BTL48_03090	ENOG4107YZX	Universal stress protein
BTL48_03100	ENOG4105E09	nadh pyrophosphatase
BTL48_03105	ENOG4105DZG	Dehydrogenase
BTL48_03125	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BTL48_03135	ENOG4108Q2J	Inner membrane protein YebE
BTL48_03140	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BTL48_03150	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
BTL48_03155	ENOG4105E9H	Lytic Murein transglycosylase
BTL48_03160	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BTL48_03165	ENOG4105D1A	Methyltransferase
BTL48_03170	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BTL48_03195	ENOG4107RZZ	dna polymerase iii epsilon subunit
BTL48_03210	ENOG4105D0S	secretion protein (HlyD
BTL48_03215	ENOG4105CJ1	ABC, transporter
BTL48_03220	ENOG4105CMI	transporter
BTL48_03240	ENOG4107SH3	glycosyl transferase, family 39
BTL48_03255	ENOG4107XM9	(LipO)protein
BTL48_03265	ENOG4105T38	integral membrane protein
BTL48_03270	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BTL48_03290	ENOG4105CMM	transposase
BTL48_03295	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BTL48_03320	ENOG4105KCK	Peptidoglycan-associated lipoprotein
BTL48_03325	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
BTL48_03335	ENOG4105M8F	Biopolymer transport protein exbD tolR
BTL48_03340	ENOG4105E02	MotA TolQ exbB proton channel
BTL48_03345	ENOG4107YD3	Thioesterase
BTL48_03350	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BTL48_03385	ENOG4105EXG	Transcriptional regulator
BTL48_03390	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BTL48_03430	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BTL48_03435	ENOG4105W2Z	cytochrome C, class I
BTL48_03440	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BTL48_03445	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
BTL48_03450	ENOG4105EW9	transcriptional regulator AsnC family
BTL48_03490	ENOG4105CMM	transposase
BTL48_03505	ENOG4105CH2	amidohydrolase
BTL48_03510	ENOG4105EKE	dihydroorotase
BTL48_03515	ENOG4105C5H	ABC transporter
BTL48_03525	ENOG4108V6E	Cell division protein mraZ
BTL48_03530	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BTL48_03535	ENOG4105N8N	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BTL48_03540	ENOG4105CJN	penicillin-binding protein
BTL48_03545	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BTL48_03550	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BTL48_03555	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BTL48_03565	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BTL48_03570	ENOG4105DFU	Cell wall formation (By similarity)
BTL48_03575	ENOG4105CPF	Cell wall formation (By similarity)
BTL48_03580	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
BTL48_03585	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BTL48_03590	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BTL48_03595	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BTL48_03610	ENOG4105DR5	peptidase
BTL48_03615	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BTL48_03635	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
BTL48_03640	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BTL48_03655	ENOG4105VCC	30S ribosomal protein S21
BTL48_03665	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BTL48_03685	ENOG4105CMM	transposase
BTL48_03695	ENOG4108ESY	Metal dependent phosphohydrolase
BTL48_03710	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
BTL48_03735	ENOG4108R4R	Iron-regulated virulence regulatory protein
BTL48_03750	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BTL48_03770	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BTL48_03790	ENOG4108Z9W	Outer membrane porin
BTL48_03795	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BTL48_03800	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BTL48_03805	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BTL48_03810	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BTL48_03820	ENOG4107QIZ	NADH dehydrogenase
BTL48_03825	ENOG4108IEH	NADH dehydrogenase subunit g
BTL48_03830	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BTL48_03835	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BTL48_03840	ENOG4105DF2	NADH dehydrogenase subunit j
BTL48_03845	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BTL48_03855	ENOG4105C8S	subunit m
BTL48_03860	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BTL48_03870	ENOG4105EAC	phosphoserine phosphatase
BTL48_03875	ENOG4108JA2	transcriptioN-repair coupling factor
BTL48_03880	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BTL48_03885	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BTL48_03895	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
BTL48_03900	ENOG4105D3R	alkyl hydroperoxide reductase
BTL48_03910	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BTL48_03920	ENOG41072GX	Peptidase M22 Glycoprotease
BTL48_03925	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
BTL48_03930	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
BTL48_03935	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BTL48_03945	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BTL48_03950	ENOG4105CDA	abc transporter atp-binding protein
BTL48_03955	ENOG4105E5Q	amino acid AbC transporter
BTL48_03960	ENOG4105EAB	amino acid AbC transporter
BTL48_03965	ENOG4107TF3	peptidylprolyl cis-trans isomerase
BTL48_03975	ENOG4107835	probably involved in intracellular septation (By similarity)
BTL48_03980	ENOG4105E0X	reductase
BTL48_03985	ENOG4108JJB	ABC transporter
BTL48_03990	ENOG4107QCX	Transporter
BTL48_04010	ENOG4105C0Z	ABC transporter
BTL48_04015	ENOG4108IV0	ABC, transporter
BTL48_04020	ENOG4105HSS	phospholipase C
BTL48_04035	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_04065	ENOG4105CSM	endonuclease III
BTL48_04070	ENOG4108R3D	Electron transport complex
BTL48_04080	ENOG4105DP0	ferredoxin-NADP reductase
BTL48_04085	ENOG4108Z4U	Ferredoxin
BTL48_04090	ENOG4107RH7	Nicotinate phosphoribosyltransferase
BTL48_04095	ENOG4105M4H	endoribonuclease L-psp
BTL48_04105	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
BTL48_04110	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BTL48_04115	ENOG4105CSH	Transporter
BTL48_04120	ENOG4105CWC	Acetylornithine deacetylase
BTL48_04125	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BTL48_04130	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BTL48_04135	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BTL48_04140	ENOG41061N2	exported protein
BTL48_04160	ENOG4105C03	ribonuclease
BTL48_04165	ENOG4105EI2	Pseudouridine synthase
BTL48_04170	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
BTL48_04175	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
BTL48_04180	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
BTL48_04185	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BTL48_04190	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BTL48_04195	ENOG4108UHJ	MAF-like protein
BTL48_04200	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
BTL48_04205	ENOG4105VGS	50s ribosomal protein l32
BTL48_04210	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BTL48_04215	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BTL48_04220	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BTL48_04225	ENOG4105CHR	reductase
BTL48_04230	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BTL48_04235	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BTL48_04245	ENOG4105EMN	RNA polymerase sigma factor
BTL48_04260	ENOG4105C0H	protease
BTL48_04275	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BTL48_04280	ENOG4105C3F	Signal peptidase i
BTL48_04285	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BTL48_04290	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BTL48_04295	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
BTL48_04300	ENOG4105BZU	Histidine kinase
BTL48_04310	ENOG4108MN8	Membrane
BTL48_04325	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BTL48_04345	ENOG4105C26	Dehydrogenase
BTL48_04350	ENOG4107R11	Transcriptional regulator
BTL48_04365	ENOG4105K4H	Nlp p60 protein
BTL48_04370	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BTL48_04375	ENOG4108ZJF	Glcg protein
BTL48_04385	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BTL48_04400	ENOG4105C5W	Aldolase
BTL48_04410	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BTL48_04435	ENOG4105D44	asparaginase
BTL48_04440	ENOG4108JQ6	ABC transporter
BTL48_04445	ENOG4105DEF	Extracellular solute-binding protein, family 5
BTL48_04450	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BTL48_04475	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BTL48_04490	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BTL48_04505	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BTL48_04510	ENOG4108Z0R	Transferase
BTL48_04515	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BTL48_04520	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BTL48_04535	ENOG4105CMM	transposase
BTL48_04555	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BTL48_04560	ENOG4108YXA	Membrane
BTL48_04565	ENOG4105DXD	2-methylcitrate dehydratase
BTL48_04570	ENOG4105BZN	citrate synthase
BTL48_04575	ENOG4105CR4	methylisocitrate lyase
BTL48_04580	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BTL48_04585	ENOG4105FDP	GntR family transcriptional regulator
BTL48_04590	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
BTL48_04595	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
BTL48_04605	ENOG4105E33	succinate dehydrogenase
BTL48_04610	ENOG41060IS	Flavinator of succinate dehydrogenase
BTL48_04615	ENOG4105BZN	citrate synthase
BTL48_04625	ENOG4105DUM	transcriptional regulator, lysR family
BTL48_04630	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BTL48_04640	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
BTL48_04645	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
BTL48_04655	ENOG4107QMZ	Dehydrogenase
BTL48_04665	ENOG4107E2E	PKHD-type hydroxylase
BTL48_04670	ENOG4108ESX	Receptor
BTL48_04680	ENOG4105C6K	Malic enzyme
BTL48_04685	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BTL48_04690	ENOG4105EPD	Oligopeptide transporter, Opt family
BTL48_04695	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BTL48_04700	ENOG4105C7S	Dehydrogenase
BTL48_04705	ENOG4107QN2	dihydrolipoyl dehydrogenase
BTL48_04710	ENOG4105D6Z	AFG1 family ATPase
BTL48_04715	ENOG4108SF5	RNA Polymerase
BTL48_04725	ENOG4105E0K	tonB-dependent siderophore receptor
BTL48_04745	ENOG4105C31	Tryptophanyl-tRNA synthetase
BTL48_04750	ENOG4105BZM	domain protein
BTL48_04755	ENOG4105DVT	helicase
BTL48_04760	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL48_04765	ENOG4105C34	Pseudouridine synthase
BTL48_04770	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
BTL48_04775	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
BTL48_04780	ENOG4105CHR	reductase
BTL48_04785	ENOG4108NVM	synthesis repressor PhaR
BTL48_04810	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BTL48_04815	ENOG4105K3G	Periplasmic Protein
BTL48_04830	ENOG4105VDW	Csbd family
BTL48_04835	ENOG4105CPW	cytochrome b561
BTL48_04850	ENOG4105BZ1	(ABC) transporter
BTL48_04865	ENOG4105ED9	Protein of unknown function (DUF455)
BTL48_04870	ENOG4105CVE	Lytic murein transglycosylase
BTL48_04880	ENOG4105BZU	Histidine kinase
BTL48_04890	ENOG4105CHR	reductase
BTL48_04895	ENOG4108KF1	Membrane
BTL48_04930	ENOG4105CMM	transposase
BTL48_04950	ENOG4106IQC	argininosuccinate lyase
BTL48_04960	ENOG4105F27	Major Facilitator
BTL48_04965	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BTL48_04970	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BTL48_04975	ENOG4105UYK	outer membrane protein a
BTL48_04980	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BTL48_04985	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BTL48_04995	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BTL48_05005	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BTL48_05010	ENOG4105CAT	Cytidine monophosphate kinase
BTL48_05015	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BTL48_05030	ENOG4105CFV	Tetratricopeptide repeat protein
BTL48_05035	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
BTL48_05040	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
BTL48_05045	ENOG4105C0B	DNA polymerase III (alpha subunit)
BTL48_05050	ENOG4105C6T	cysteine synthase
BTL48_05055	ENOG4105CVE	Lytic murein transglycosylase
BTL48_05065	ENOG4105BZJ	Electron transfer flavoprotein
BTL48_05070	ENOG4105C10	Electron transfer flavoprotein
BTL48_05080	ENOG4105CSU	acyl-Coa dehydrogenase
BTL48_05085	ENOG4105D3R	alkyl hydroperoxide reductase
BTL48_05090	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BTL48_05095	ENOG4108I5D	sulfate abc transporter
BTL48_05100	ENOG4105ECW	sulfate abc transporter
BTL48_05135	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BTL48_05145	ENOG4105P8F	nudix hydrolase
BTL48_05150	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
BTL48_05155	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BTL48_05160	ENOG4105D0M	Protease HtpX homolog
BTL48_05165	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BTL48_05175	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
BTL48_05180	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
BTL48_05185	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
BTL48_05190	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
BTL48_05195	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
BTL48_05200	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BTL48_05205	ENOG4105C26	Dehydrogenase
BTL48_05210	ENOG4108UKI	Enoyl-CoA hydratase
BTL48_05215	ENOG4108ZJI	phenylacetic acid degradation protein
BTL48_05245	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BTL48_05255	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BTL48_05260	ENOG4105CV6	ABC transporter, permease
BTL48_05270	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
BTL48_05280	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BTL48_05285	ENOG4105F38	ABC transporter, permease
BTL48_05290	ENOG4105D38	putrescine abc transporter
BTL48_05300	ENOG4108RB4	3-methyladenine DNA glycosylase
BTL48_05310	ENOG4107QSV	RmuC domain protein
BTL48_05320	ENOG4105E66	phosphoriboisomerase A
BTL48_05325	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BTL48_05330	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
BTL48_05335	ENOG4108EKC	n-acetylglutamate synthase
BTL48_05340	ENOG4105CQ7	ATP-dependent helicase
BTL48_05350	ENOG4105C0B	DNA polymerase III (alpha subunit)
BTL48_05355	ENOG4105CPK	Glycosyl transferase (Group 1
BTL48_05360	ENOG4107BJW	polysaccharide deacetylase
BTL48_05365	ENOG4106WTF	Glycosyl transferase, family 2
BTL48_05385	ENOG4105KRS	Proteinase inhibitor
BTL48_05400	ENOG4105BZ1	(ABC) transporter
BTL48_05420	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BTL48_05425	ENOG4105D0M	Protease HtpX homolog
BTL48_05435	ENOG4105KHC	sulfurtransferase
BTL48_05470	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BTL48_05475	ENOG4105CTB	Polyprenyl synthetase
BTL48_05480	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BTL48_05485	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BTL48_05490	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BTL48_05500	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BTL48_05505	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BTL48_05515	ENOG4105CDU	Replicative dna helicase
BTL48_05535	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BTL48_05540	ENOG4108IAB	Phoh family
BTL48_05545	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTL48_05550	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
BTL48_05555	ENOG4105CHM	Aminotransferase
BTL48_05560	ENOG4105D6E	homoserine dehydrogenase
BTL48_05575	ENOG4105CMM	transposase
BTL48_05580	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BTL48_05585	ENOG4105CD8	aminopeptidase N
BTL48_05595	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
BTL48_05600	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BTL48_05605	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BTL48_05620	ENOG4105CMM	transposase
BTL48_05630	ENOG4105CQB	FAD linked oxidase domain protein
BTL48_05635	ENOG4105EU8	FAD linked oxidase domain protein
BTL48_05640	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BTL48_05645	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BTL48_05650	ENOG4105W8H	transhydrogenase (subunit alpha
BTL48_05675	ENOG4105ETT	transcriptional Regulator, LysR family
BTL48_05680	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BTL48_05690	ENOG4108U78	Glutathione S-transferase
BTL48_05695	ENOG4107QTF	adenylosuccinate lyase
BTL48_05700	ENOG4105T86	cytochrome C
BTL48_05715	ENOG4105CMM	transposase
BTL48_05740	ENOG4105BZU	Histidine kinase
BTL48_05750	ENOG4105CMM	transposase
BTL48_05760	ENOG4105F9F	transposase
BTL48_05780	ENOG41067HS	methyltransferase
BTL48_05800	ENOG4105CBC	glutamate synthase
BTL48_05805	ENOG41066VF	YeeE YedE family protein
BTL48_05815	ENOG4105RK9	auxin efflux carrier
BTL48_05820	ENOG41082BV	acetyltransferase
BTL48_05840	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BTL48_05845	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BTL48_05850	ENOG4108IQK	o-acetylhomoserine
BTL48_05855	ENOG4105K70	DNA-binding protein
BTL48_05880	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BTL48_05885	ENOG4105DHQ	Histidine kinase
BTL48_05890	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BTL48_05910	ENOG4105CMM	transposase
BTL48_05915	ENOG4105CDH	Citrulline--aspartate ligase
BTL48_05920	ENOG4105DBV	ornithine carbamoyltransferase
BTL48_05925	ENOG4105C8Y	Acetylornithine aminotransferase
BTL48_05935	ENOG4105C5I	Dehydrogenase
BTL48_05950	ENOG4105JXH	GntR family transcriptional regulator
BTL48_05980	ENOG4105CNV	Aldolase
BTL48_05985	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
BTL48_06040	ENOG4105CJR	Integral membrane protein (MviN
BTL48_06050	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BTL48_06055	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BTL48_06060	ENOG4105W49	UPF0434 protein
BTL48_06065	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
BTL48_06070	ENOG4105M8F	Biopolymer transport protein exbD tolR
BTL48_06080	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BTL48_06085	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BTL48_06090	ENOG4105CMM	transposase
BTL48_06115	ENOG4105VEQ	Cold shock protein
BTL48_06120	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BTL48_06135	ENOG4108JQB	penicillin-binding protein 1C
BTL48_06150	ENOG4105DY2	Paraquat-inducible protein b
BTL48_06160	ENOG4105C26	Dehydrogenase
BTL48_06170	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_06175	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BTL48_06180	ENOG4105C0Z	ABC transporter
BTL48_06185	ENOG4108IV0	ABC, transporter
BTL48_06195	ENOG4105BZU	Histidine kinase
BTL48_06200	ENOG4108YZA	Nitrogen regulatory protein pii
BTL48_06225	ENOG4105W0Z	cytoplasmic protein
BTL48_06230	ENOG4105C0P	Mg chelatase subunit ChlI
BTL48_06235	ENOG4105VJV	50s ribosomal protein L35
BTL48_06240	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BTL48_06245	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BTL48_06250	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BTL48_06255	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BTL48_06285	ENOG4105DRR	Transcriptional regulator, GntR family
BTL48_06300	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BTL48_06315	ENOG4105VEQ	Cold shock protein
BTL48_06325	ENOG4105C94	Transporter
BTL48_06345	ENOG4108YXU	transcriptional regulator AsnC family
BTL48_06395	ENOG4108JJ7	ABC transporter
BTL48_06400	ENOG4105CV8	reductase
BTL48_06410	ENOG4105CMM	transposase
BTL48_06420	ENOG4105CPC	Aldo Keto reductase
BTL48_06435	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BTL48_06440	ENOG4108JQC	penicillin-binding protein 1A
BTL48_06475	ENOG4105KTH	gatB Yqey
BTL48_06480	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BTL48_06490	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BTL48_06510	ENOG4105CEY	Amp-dependent synthetase and ligase
BTL48_06525	ENOG4105CHU	acetyl-coa acetyltransferase
BTL48_06535	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
BTL48_06540	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BTL48_06545	ENOG4105CHU	acetyl-coa acetyltransferase
BTL48_06550	ENOG4107QPN	acyl-Coa dehydrogenase
BTL48_06560	ENOG4105D7W	serine acetyltransferase
BTL48_06570	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BTL48_06575	ENOG4105ECY	inositol monophosphatase
BTL48_06580	ENOG4105C26	Dehydrogenase
BTL48_06585	ENOG4108JPW	Aminotransferase
BTL48_06600	ENOG4105C4R	Atp-dependent dna helicase
BTL48_06605	ENOG4105D7N	magnesium and cobalt transport protein CorA
BTL48_06615	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
BTL48_06625	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BTL48_06630	ENOG4108JQ6	ABC transporter
BTL48_06640	ENOG4105C6Z	Gluconate
BTL48_06650	ENOG41067MG	lrgb family
BTL48_06665	ENOG4108RMU	ferritin dps family protein
BTL48_06685	ENOG4108UYB	regulatoR
BTL48_06690	ENOG4105E2S	oxidase) subunit II
BTL48_06695	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BTL48_06700	ENOG4105CCU	oxidase (Subunit III)
BTL48_06705	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
BTL48_06710	ENOG4105EUB	pirin domain protein
BTL48_06730	ENOG4105EUB	pirin domain protein
BTL48_06740	ENOG4107SDU	Methyl-accepting chemotaxis
BTL48_06745	ENOG4108K5P	(LipO)protein
BTL48_06755	ENOG4108VPT	UPF0234 protein
BTL48_06780	ENOG4105CHR	reductase
BTL48_06785	ENOG4107AQZ	Membrane
BTL48_06790	ENOG41068KF	Universal stress protein
BTL48_06810	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BTL48_06820	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
BTL48_06830	ENOG4107QIZ	NADH dehydrogenase
BTL48_06845	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BTL48_06850	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BTL48_06855	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BTL48_06860	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BTL48_06865	ENOG4108ZAF	Molybdopterin
BTL48_06875	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BTL48_06880	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
BTL48_06905	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BTL48_06915	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BTL48_06925	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BTL48_06930	ENOG4105CJ2	(LipO)protein
BTL48_06970	ENOG4105FE1	phytoene synthase
BTL48_06975	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BTL48_06990	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BTL48_07005	ENOG4107QI1	Mate efflux family protein
BTL48_07015	ENOG4105NRA	50s ribosomal protein l31 type b
BTL48_07020	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
BTL48_07025	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
BTL48_07030	ENOG4105W5Q	DNA repair protein (RadC
BTL48_07045	ENOG4108RXX	maleylacetoacetate isomerase
BTL48_07065	ENOG4105CKI	cobalamin synthesis protein
BTL48_07075	ENOG4105EJC	lysr family transcriptional regulator
BTL48_07085	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BTL48_07090	ENOG4105FE9	pseudouridine synthase
BTL48_07095	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BTL48_07100	ENOG4105CHV	Transcription elongation factor NusA
BTL48_07105	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BTL48_07110	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BTL48_07115	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BTL48_07135	ENOG4105DRR	Transcriptional regulator, GntR family
BTL48_07145	ENOG4105E39	Enoyl-CoA hydratase
BTL48_07150	ENOG4105CEY	Amp-dependent synthetase and ligase
BTL48_07160	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BTL48_07175	ENOG4105C7J	ABC transporter, permease
BTL48_07180	ENOG4105D5T	phosphonate abc transporter
BTL48_07185	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BTL48_07190	ENOG4105E0C	molybdate abc transporter
BTL48_07200	ENOG4105F4R	Transcriptional regulator mode
BTL48_07220	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BTL48_07225	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BTL48_07230	ENOG4105BZS	acriflavin resistance protein
BTL48_07235	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BTL48_07240	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BTL48_07245	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BTL48_07250	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
BTL48_07255	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BTL48_07260	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BTL48_07270	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BTL48_07280	ENOG4105K56	Transcriptional regulator
BTL48_07285	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BTL48_07290	ENOG4105DA5	(ABC) transporter
BTL48_07300	ENOG4105IPI	Membrane
BTL48_07305	ENOG4105BZU	Histidine kinase
BTL48_07315	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
BTL48_07325	ENOG4105D94	Major Facilitator Superfamily
BTL48_07345	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
BTL48_07355	ENOG4105VRT	cytoplasmic protein
BTL48_07370	ENOG4108YZ4	nudix hydrolase
BTL48_07375	ENOG410811Q	Ferredoxin
BTL48_07380	ENOG4108TZV	Membrane
BTL48_07385	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BTL48_07410	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BTL48_07415	ENOG4105C9A	Phoh family
BTL48_07420	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BTL48_07425	ENOG4108JU5	Magnesium and cobalt efflux protein
BTL48_07430	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
BTL48_07435	ENOG4108FN7	Aldo keto reductase
BTL48_07455	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BTL48_07460	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BTL48_07465	ENOG4105VIE	preprotein translocase, subunit YajC
BTL48_07470	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BTL48_07475	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BTL48_07480	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
BTL48_07485	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BTL48_07490	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BTL48_07500	ENOG4105TNS	Conserved Protein
BTL48_07520	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
BTL48_07525	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
BTL48_07530	ENOG4105CHM	Aminotransferase
BTL48_07540	ENOG4105C6K	Malic enzyme
BTL48_07555	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BTL48_07560	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BTL48_07565	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BTL48_07570	ENOG4105BZA	Phosphoglycerate kinase
BTL48_07585	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BTL48_07600	ENOG4108SHQ	Glutathione S-transferase
BTL48_07620	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
BTL48_07635	ENOG4105CJ3	phosphate transporter
BTL48_07640	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BTL48_07650	ENOG4105DR5	peptidase
BTL48_07660	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BTL48_07705	ENOG4108R6G	acetyltransferase
BTL48_07710	ENOG4105CK2	sodium dicarboxylate symporter
BTL48_07720	ENOG4105C8V	SAICAR synthetase
BTL48_07725	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BTL48_07730	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BTL48_07735	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BTL48_07765	ENOG4105MP9	class II Aldolase
BTL48_07775	ENOG4105C1G	acyl-Coa dehydrogenase
BTL48_07780	ENOG4105C7K	acetolactate synthase
BTL48_07785	ENOG4105ETT	transcriptional Regulator, LysR family
BTL48_07790	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BTL48_07795	ENOG4108Z66	YbaK ebsC protein
BTL48_07800	ENOG41061WM	D-Alanyl-D-Alanine
BTL48_07810	ENOG4107QNK	)-transporter
BTL48_07830	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BTL48_07835	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BTL48_07840	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BTL48_07860	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BTL48_07865	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BTL48_07870	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BTL48_07875	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BTL48_07885	ENOG4105CHR	reductase
BTL48_07890	ENOG4105CVJ	phosphoglycerate mutase
BTL48_07895	ENOG4105DUM	transcriptional regulator, lysR family
BTL48_07920	ENOG4105C2W	permease
BTL48_07925	ENOG41067QW	Transcriptional regulator
BTL48_07935	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BTL48_07940	ENOG4105HBR	Rna-binding protein
BTL48_07945	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
BTL48_07950	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BTL48_07960	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BTL48_07970	ENOG4105C9X	ppx gppa phosphatase
BTL48_07975	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BTL48_07980	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BTL48_07985	ENOG4105C8U	phosphate abc transporter
BTL48_07990	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BTL48_08010	ENOG4105CMM	transposase
BTL48_08040	ENOG4105CMM	transposase
BTL48_08060	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BTL48_08095	ENOG4105CXT	aspartate transcarbamylase
BTL48_08100	ENOG4105DH7	May be involved in recombination (By similarity)
BTL48_08110	ENOG4105CSH	Transporter
BTL48_08115	ENOG4105DHQ	Histidine kinase
BTL48_08125	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BTL48_08130	ENOG4108004	Modulates RecA activity (By similarity)
BTL48_08135	ENOG4105DZ2	Transcriptional regulator
BTL48_08140	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BTL48_08155	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BTL48_08160	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BTL48_08165	ENOG4108ZCF	integral membrane protein
BTL48_08170	ENOG4108ZCF	integral membrane protein
BTL48_08175	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BTL48_08195	ENOG4105F0N	pyrophosphate phospho-hydrolase
BTL48_08215	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BTL48_08255	ENOG4105GVR	general secretion pathway protein D
BTL48_08270	ENOG4105CMM	transposase
BTL48_08300	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BTL48_08310	ENOG4107S2Z	UPF0761 membrane protein
BTL48_08320	ENOG4105CNG	UPF0061 protein
BTL48_08330	ENOG41062D9	Histidine kinase
BTL48_08335	ENOG4105BZU	Histidine kinase
BTL48_08340	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BTL48_08345	ENOG4105D0M	Protease HtpX homolog
BTL48_08350	ENOG4105WH1	Two component transcriptional regulator luxr family
BTL48_08375	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BTL48_08380	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BTL48_08390	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BTL48_08395	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BTL48_08405	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BTL48_08410	ENOG4105CH5	extracellular solute-binding protein, family 7
BTL48_08415	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BTL48_08470	ENOG4105D4P	Coproporphyrinogen iii oxidase
BTL48_08475	ENOG41068CG	regulatoR
BTL48_08480	ENOG4105C22	threonyL-tRNA synthetase
BTL48_08485	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BTL48_08490	ENOG4105D7Z	glutathione synthase
BTL48_08500	ENOG41080Z8	PHOSPHOCARRIER protein
BTL48_08505	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BTL48_08515	ENOG4108Z9K	Osmotically inducible protein
BTL48_08550	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BTL48_08600	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BTL48_08605	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BTL48_08610	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BTL48_08615	ENOG4105DTN	riboflavin biosynthesis protein ribF
BTL48_08640	ENOG4105CMM	transposase
BTL48_08650	ENOG4105C4R	Atp-dependent dna helicase
BTL48_08655	ENOG4105PE1	Receptor
BTL48_08660	ENOG4105C5H	ABC transporter
BTL48_08665	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
BTL48_08670	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BTL48_08675	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BTL48_08730	ENOG4105CMM	transposase
BTL48_08750	ENOG4105CMM	transposase
BTL48_08765	ENOG4105HSS	phospholipase C
BTL48_08770	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BTL48_08795	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BTL48_08815	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
BTL48_08835	ENOG4108JQ1	Dehydrogenase
BTL48_08840	ENOG4105BZU	Histidine kinase
BTL48_08860	ENOG4105YK5	50S ribosomal protein L36
BTL48_08865	ENOG4105CC0	LysR family Transcriptional regulator
BTL48_08870	ENOG4105CHR	reductase
BTL48_08880	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
BTL48_08885	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
BTL48_08895	ENOG4107QN2	dihydrolipoyl dehydrogenase
BTL48_08900	ENOG4107QSN	dihydrolipoamide acetyltransferase
BTL48_08905	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BTL48_08910	ENOG4105BZU	Histidine kinase
BTL48_08915	ENOG4108ZXC	Two component transcriptional regulator, luxr family
BTL48_08920	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BTL48_08925	ENOG4105DGW	oligopeptidase A
BTL48_08950	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BTL48_08955	ENOG4105BZS	acriflavin resistance protein
BTL48_08960	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BTL48_08970	ENOG4105FE9	pseudouridine synthase
BTL48_08975	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
BTL48_08980	ENOG4105F9N	Major Facilitator Superfamily
BTL48_08985	ENOG4108VWS	Yaeq family
BTL48_09005	ENOG4108IV0	ABC, transporter
BTL48_09025	ENOG4105C2J	ABC transporter
BTL48_09030	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BTL48_09035	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_09040	ENOG4106KR7	LysR family Transcriptional regulator
BTL48_09050	ENOG4105C7B	Threonine dehydratase
BTL48_09070	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BTL48_09075	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BTL48_09090	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BTL48_09095	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BTL48_09100	ENOG4108ZP8	Acetolactate synthase small subunit
BTL48_09105	ENOG4105C7K	acetolactate synthase
BTL48_09130	ENOG4105D1Q	UPF0246 protein
BTL48_09140	ENOG4105DTD	Dehydrogenase
BTL48_09185	ENOG4108RWP	Major Facilitator Superfamily protein
BTL48_09190	ENOG4105CNM	Receptor
BTL48_09225	ENOG4105C5I	Dehydrogenase
BTL48_09260	ENOG4106BRA	Membrane
BTL48_09270	ENOG4105F2V	VRR-NUC domain-containing protein
BTL48_09280	ENOG4105FDF	Could be involved in DNA repair (By similarity)
BTL48_09285	ENOG4105DQE	DNA ligase
BTL48_09295	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BTL48_09300	ENOG4105D0S	secretion protein (HlyD
BTL48_09305	ENOG4105CJ1	ABC, transporter
BTL48_09310	ENOG4105CMI	transporter
BTL48_09320	ENOG4105CHR	reductase
BTL48_09325	ENOG41068KF	Universal stress protein
BTL48_09330	ENOG4105MGM	doxx family
BTL48_09360	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BTL48_09365	ENOG4105WAP	TPR repeat-containing protein
BTL48_09395	ENOG4105DF9	Lipoate-protein, ligase
BTL48_09405	ENOG4105D82	Glutamate dehydrogenase
BTL48_09415	ENOG41088SP	formiminoglutamate hydrolase
BTL48_09425	ENOG4105EAD	ABC transporter
BTL48_09430	ENOG4105EAB	amino acid AbC transporter
BTL48_09445	ENOG4105F8V	Hydrolase, tatD family
BTL48_09450	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BTL48_09455	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BTL48_09460	ENOG4105HHA	aminodeoxychorismate lyase
BTL48_09475	ENOG4105DND	Transcriptional regulator
BTL48_09495	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BTL48_09500	ENOG4108IPT	Naphthoate synthase
BTL48_09510	ENOG4105VDB	UPF0125 protein
BTL48_09520	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BTL48_09540	ENOG4105BZU	Histidine kinase
BTL48_09560	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BTL48_09565	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BTL48_09570	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BTL48_09585	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BTL48_09590	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BTL48_09600	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BTL48_09605	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BTL48_09615	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL48_09620	ENOG4105DZP	Membrane-associated zinc metalloprotease
BTL48_09625	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BTL48_09630	ENOG4105KNE	Phosphatidate cytidylyltransferase
BTL48_09635	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BTL48_09640	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BTL48_09645	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BTL48_09650	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BTL48_09655	ENOG4105CE9	30S ribosomal protein S2
BTL48_09660	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BTL48_09665	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
BTL48_09680	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BTL48_09685	ENOG4105E96	Colicin v production protein
BTL48_09695	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BTL48_09735	ENOG4105MQ3	flagellar protein FliS
BTL48_09750	ENOG4105D00	flagellar biosynthetic protein flhB
BTL48_09760	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BTL48_09765	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BTL48_09770	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BTL48_09775	ENOG4108CG0	Flagellar assembly protein
BTL48_09795	ENOG4107ZI8	flagellar basal body-associated protein flil
BTL48_09800	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BTL48_09805	ENOG4105DD5	Flagellar motor switch protein
BTL48_09815	ENOG4105CN7	Flagellar biosynthetic protein FliP
BTL48_09820	ENOG4105VS8	Flagellar biosynthetic protein fliq
BTL48_09825	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
BTL48_09830	ENOG4105C8Q	Methyl-accepting chemotaxis
BTL48_09835	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
BTL48_09845	ENOG4107RD7	Flagellar Motor Protein, MotA
BTL48_09850	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
BTL48_09855	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
BTL48_09860	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BTL48_09890	ENOG4107RNH	Outer membrane receptor FepA
BTL48_09900	ENOG410620I	Diguanylate cyclase
BTL48_09910	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BTL48_09920	ENOG4105E9K	Isocitrate dehydrogenase
BTL48_09935	ENOG4105CDA	abc transporter atp-binding protein
BTL48_09940	ENOG4105E5Q	amino acid AbC transporter
BTL48_09945	ENOG4105EAB	amino acid AbC transporter
BTL48_09970	ENOG4108IV0	ABC, transporter
BTL48_09975	ENOG4105C0Z	ABC transporter
BTL48_10005	ENOG4105EE5	Membrane protein terC
BTL48_10015	ENOG4108WQH	regulatoR
BTL48_10020	ENOG4105BZU	Histidine kinase
BTL48_10040	ENOG4105CMM	transposase
BTL48_10045	ENOG4105CVK	Glutamate decarboxylase
BTL48_10050	ENOG4105D0C	transport protein
BTL48_10055	ENOG4105K78	MarR family Transcriptional regulator
BTL48_10065	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BTL48_10075	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BTL48_10085	ENOG4105C7K	acetolactate synthase
BTL48_10095	ENOG4105C26	Dehydrogenase
BTL48_10105	ENOG4105DJ4	phosphatidylserine decarboxylase
BTL48_10110	ENOG4105DMF	Dehydrogenase
BTL48_10115	ENOG4105D01	(LipO)protein
BTL48_10120	ENOG4105CMM	transposase
BTL48_10135	ENOG4108SXK	Transporter Drug Metabolite Exporter family
BTL48_10140	ENOG4105D8V	Glucose sorbosone dehydrogenase
BTL48_10145	ENOG4108K3A	Glutathione S-transferase
BTL48_10160	ENOG4108IV0	ABC, transporter
BTL48_10165	ENOG4105C0Z	ABC transporter
BTL48_10170	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BTL48_10175	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_10180	ENOG4105CP9	extracellular ligand-binding receptor
BTL48_10185	ENOG4105EX9	Membrane
BTL48_10190	ENOG4105II7	pyrroline-5-carboxylate reductase
BTL48_10200	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
BTL48_10210	ENOG4108IJ9	(ABC) transporter
BTL48_10220	ENOG4105CP9	extracellular ligand-binding receptor
BTL48_10230	ENOG4107QQG	Dehydrogenase
BTL48_10245	ENOG4107TAE	Glycosyl transferase (Group 1
BTL48_10270	ENOG4105K64	Glycosyl transferase, family 2
BTL48_10290	ENOG4105C5Q	Transcriptional regulator
BTL48_10295	ENOG4105CB5	ATP-dependent DNA helicase recG
BTL48_10300	ENOG4105KME	endoribonuclease L-psp
BTL48_10315	ENOG4105DP0	ferredoxin-NADP reductase
BTL48_10320	ENOG4107QKW	extracellular solute-binding protein family 1
BTL48_10330	ENOG4108UCS	ABC, transporter
BTL48_10335	ENOG4105EUB	pirin domain protein
BTL48_10345	ENOG4105EQ1	Transcriptional regulator
BTL48_10350	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BTL48_10355	ENOG4105CUX	Signal transduction histidine kinase
BTL48_10360	ENOG4105C5F	glutamine synthetase
BTL48_10365	ENOG4105CSA	Coproporphyrinogen iii oxidase
BTL48_10370	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BTL48_10375	ENOG4105BZU	Histidine kinase
BTL48_10380	ENOG4105C8Q	Methyl-accepting chemotaxis
BTL48_10390	ENOG4105DND	Transcriptional regulator
BTL48_10395	ENOG4105C1G	acyl-Coa dehydrogenase
BTL48_10400	ENOG4108PGP	mmge prpd family protein
BTL48_10410	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BTL48_10415	ENOG4105DSJ	YicC domain protein
BTL48_10425	ENOG4105FYV	Amp nucleosidase
BTL48_10430	ENOG4108YS0	lipoprotein YafL
BTL48_10435	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
BTL48_10440	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BTL48_10445	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BTL48_10450	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BTL48_10455	ENOG4105CDA	abc transporter atp-binding protein
BTL48_10460	ENOG4105E5Q	amino acid AbC transporter
BTL48_10465	ENOG4107R0W	ABC transporter
BTL48_10475	ENOG4108YH7	hemolysin
BTL48_10490	ENOG4105GQR	Chaperone
BTL48_10515	ENOG4108QZZ	filamentous hemagglutinin
BTL48_10525	ENOG4108I0Y	(ABC) transporter
BTL48_10530	ENOG4108UJV	acyl-CoA thioesterase i
BTL48_10535	ENOG4105EIN	peptidylprolyl cis-trans isomerase
BTL48_10540	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
BTL48_10545	ENOG4105D6S	protein involved in catabolism of external DNA
BTL48_10555	ENOG4105EHV	domain protein
BTL48_10575	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BTL48_10585	ENOG4105CMM	transposase
BTL48_10605	ENOG4108K5P	(LipO)protein
BTL48_10610	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BTL48_10615	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BTL48_10620	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BTL48_10640	ENOG4105GAK	amidohydrolase 2
BTL48_10645	ENOG4105C5Q	Transcriptional regulator
BTL48_10650	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BTL48_10655	ENOG4105C7N	Xanthine uracil vitamin C permease
BTL48_10660	ENOG4105DEN	Luciferase family
BTL48_10665	ENOG41080RH	Thioredoxin
BTL48_10700	ENOG4105C5H	ABC transporter
BTL48_10705	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BTL48_10710	ENOG4108Z6B	deaminase
BTL48_10715	ENOG4106TCE	
BTL48_10725	ENOG4105KJM	monovalent cation h antiporter subunit g
BTL48_10730	ENOG4105W4C	monovalent cation H antiporter subunit F
BTL48_10735	ENOG4105SC1	monovalent cation H antiporter subunit E
BTL48_10740	ENOG4107R4Z	monovalent cation h antiporter subunit d
BTL48_10745	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BTL48_10750	ENOG4105D65	subunit l
BTL48_10775	ENOG4107RH8	nuclease SbcCD subunit D
BTL48_10785	ENOG4105EW9	transcriptional regulator AsnC family
BTL48_10805	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BTL48_10810	ENOG4105E98	transcriptional regulator DeoR family
BTL48_10815	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BTL48_10825	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BTL48_10830	ENOG4108IG5	Transcriptional regulator
BTL48_10840	ENOG4105CJ1	ABC, transporter
BTL48_10845	ENOG4107QWP	ABC-2 type transporter
BTL48_10855	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
BTL48_10885	ENOG4108YZN	class I peptide chain release factor
BTL48_10890	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BTL48_10910	ENOG4105C8Q	Methyl-accepting chemotaxis
BTL48_10925	ENOG4105C0B	DNA polymerase III (alpha subunit)
BTL48_10940	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BTL48_10945	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
BTL48_10985	ENOG4105DC8	reductase
BTL48_10995	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BTL48_11015	ENOG4105ECQ	AraC Family Transcriptional Regulator
BTL48_11020	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
BTL48_11055	ENOG4108JCI	Transcriptional regulator
BTL48_11085	ENOG4105HEI	LysR family (Transcriptional regulator
BTL48_11090	ENOG4105F27	Major Facilitator
BTL48_11105	ENOG4105CNM	Receptor
BTL48_11110	ENOG4105WPR	Transcriptional regulator, ARAC family
BTL48_11115	ENOG4105DJ2	Major Facilitator Superfamily
BTL48_11120	ENOG4105R1U	AraC Family Transcriptional Regulator
BTL48_11125	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BTL48_11130	ENOG4105F27	Major Facilitator
BTL48_11145	ENOG4105C26	Dehydrogenase
BTL48_11150	ENOG4108IV0	ABC, transporter
BTL48_11155	ENOG4105C0Z	ABC transporter
BTL48_11180	ENOG4108M0I	Transcriptional regulator
BTL48_11200	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BTL48_11225	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BTL48_11230	ENOG4107Z6X	Transcriptional regulator
BTL48_11235	ENOG4105CHR	reductase
BTL48_11265	ENOG4107R3N	Filamentation induced by cAMP protein fic
BTL48_11275	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BTL48_11280	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BTL48_11290	ENOG4105NTW	Transcriptional regulator
BTL48_11305	ENOG4105E1J	oxidoreductase
BTL48_11310	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BTL48_11335	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BTL48_11340	ENOG4105C3U	ABC transporter
BTL48_11345	ENOG4108JQ7	(ABC) transporter
BTL48_11350	ENOG4105DEF	Extracellular solute-binding protein, family 5
BTL48_11390	ENOG4108ETH	Formylglycinamide ribotide synthetase
BTL48_11395	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
BTL48_11420	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BTL48_11425	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BTL48_11430	ENOG4108RRZ	Transcription elongation factor GreB
BTL48_11435	ENOG4105DB7	PHP domain protein
BTL48_11470	ENOG4105W7K	Transcriptional regulator
BTL48_11485	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BTL48_11495	ENOG4105C26	Dehydrogenase
BTL48_11505	ENOG4105F04	LysR family Transcriptional regulator
BTL48_11520	ENOG4105DG4	malate L-lactate dehydrogenase
BTL48_11525	ENOG4108JQ1	Dehydrogenase
BTL48_11555	ENOG4105GAK	amidohydrolase 2
BTL48_11580	ENOG4108SF5	RNA Polymerase
BTL48_11585	ENOG4108S3W	Anti-feci sigma factor, fecr
BTL48_11595	ENOG4105F8V	Hydrolase, tatD family
BTL48_11600	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BTL48_11615	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BTL48_11625	ENOG410904N	short-chain dehydrogenase reductase
BTL48_11630	ENOG4105CRK	lysyL-tRNA synthetase
BTL48_11640	ENOG4108Z5K	methylglyoxal synthase
BTL48_11690	ENOG4105WVQ	Fe-S assembly protein IscX
BTL48_11695	ENOG4108ZIT	Ferredoxin, 2FE-2S
BTL48_11700	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
BTL48_11705	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
BTL48_11710	ENOG4108Z4V	iron-sulfur cluster assembly
BTL48_11715	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
BTL48_11720	ENOG4105C3J	Cysteine desulfurase
BTL48_11725	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
BTL48_11735	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BTL48_11740	ENOG4105CGF	Aromatic amino acid aminotransferase
BTL48_11750	ENOG4105ETT	transcriptional Regulator, LysR family
BTL48_11805	ENOG4105CMM	transposase
BTL48_11810	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BTL48_11820	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BTL48_11825	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BTL48_11830	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BTL48_11835	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BTL48_11840	ENOG4108TEB	UPF0114 protein
BTL48_11850	ENOG4105CMM	transposase
BTL48_11900	ENOG4105C03	ribonuclease
BTL48_11910	ENOG4105CMM	transposase
BTL48_11930	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
BTL48_11940	ENOG4105CW7	secretion protein, HlyD family
BTL48_11945	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BTL48_11950	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BTL48_11970	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
BTL48_11980	ENOG4105D7A	ATP-binding protein
BTL48_11985	ENOG4105CDY	transcriptional regulatory protein
BTL48_11990	ENOG4105C12	Phosphoribosylglycinamide synthetase
BTL48_11995	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BTL48_12000	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BTL48_12005	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
BTL48_12010	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BTL48_12015	ENOG4108Z03	MAF-like protein
BTL48_12070	ENOG4105DSE	periplasmic solute binding protein
BTL48_12075	ENOG4105DIK	(ABC) transporter
BTL48_12080	ENOG4105CC5	ABC transporter
BTL48_12085	ENOG4105CC5	ABC transporter
BTL48_12120	ENOG4105DZG	Dehydrogenase
BTL48_12130	ENOG4105CHB	tonB-dependent Receptor
BTL48_12135	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BTL48_12150	ENOG4105CFH	Aspartokinase
BTL48_12155	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BTL48_12160	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BTL48_12170	ENOG4105C8N	cysteinyl-tRNA synthetase
BTL48_12180	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BTL48_12185	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BTL48_12190	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BTL48_12195	ENOG4105EE5	Membrane protein terC
BTL48_12200	ENOG4105ECY	inositol monophosphatase
BTL48_12245	ENOG4105GVF	(ABC) transporter
BTL48_12255	ENOG4108IJ6	ABC transporter
BTL48_12270	ENOG4105DRR	Transcriptional regulator, GntR family
BTL48_12290	ENOG4105WKW	Pfam:DUF1458
BTL48_12300	ENOG4105CIS	alcohol dehydrogenase
BTL48_12310	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BTL48_12315	ENOG4105EZE	Cupin 4 family protein
BTL48_12325	ENOG4105GJM	(LipO)protein
BTL48_12330	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BTL48_12335	ENOG4108Z4T	Peptidase M50
BTL48_12340	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
BTL48_12345	ENOG4105CGZ	zinc metallopeptidase
BTL48_12375	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BTL48_12385	ENOG4105CSP	Major Facilitator Superfamily
BTL48_12465	ENOG4105BZU	Histidine kinase
BTL48_12470	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
BTL48_12490	ENOG4105C1G	acyl-Coa dehydrogenase
BTL48_12495	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BTL48_12500	ENOG4107EJG	GntR family transcriptional regulator
BTL48_12525	ENOG4108SF5	RNA Polymerase
BTL48_12545	ENOG4105CMM	transposase
BTL48_12565	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
BTL48_12575	ENOG4105ERH	Fumarylacetoacetate hydrolase
BTL48_12595	ENOG4108IPW	abc transporter atp-binding protein
BTL48_12600	ENOG4105CM4	permease protein
BTL48_12605	ENOG4105DHS	permease protein
BTL48_12615	ENOG4105JNK	Glycosyl transferase (Group 1
BTL48_12620	ENOG4107EJC	Preprotein translocase subunit SecG
BTL48_12625	ENOG4105CP7	Triose-phosphate isomerase
BTL48_12650	ENOG4108YZA	Nitrogen regulatory protein pii
BTL48_12655	ENOG4105C4K	Nad synthetase
BTL48_12660	ENOG4105CUY	Mechanosensitive ion channel
BTL48_12665	ENOG4105CH7	arginosuccinase
BTL48_12675	ENOG4105W1Y	Transcriptional regulator
BTL48_12685	ENOG4108K0D	peptidase, M48
BTL48_12690	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BTL48_12715	ENOG4105E39	Enoyl-CoA hydratase
BTL48_12720	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BTL48_12740	ENOG4108MGN	ATP-binding component of a transport system
BTL48_12780	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BTL48_12785	ENOG4105D1H	recombination factor protein RarA
BTL48_12790	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
BTL48_12795	ENOG4105CNU	cell division protein FtsK
BTL48_12800	ENOG4105C3M	thioredoxin reductase
BTL48_12805	ENOG4105C98	muts2 protein
BTL48_12820	ENOG4107QN1	sodium solute
BTL48_12835	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BTL48_12840	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BTL48_12845	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
BTL48_12855	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BTL48_12890	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BTL48_12915	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BTL48_12920	ENOG4105CFG	Acts as a chaperone (By similarity)
BTL48_12930	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BTL48_12940	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BTL48_12945	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BTL48_12950	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BTL48_12955	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BTL48_12985	ENOG41090R7	Ferric uptake
BTL48_12990	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BTL48_12995	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BTL48_13020	ENOG4105CMM	transposase
BTL48_13025	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
BTL48_13035	ENOG4108I0Z	Aconitate hydratase
BTL48_13040	ENOG4105C7F	AcnD-accessory protein PrpF
BTL48_13065	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
BTL48_13070	ENOG4105CR4	methylisocitrate lyase
BTL48_13075	ENOG4105DRR	Transcriptional regulator, GntR family
BTL48_13080	ENOG4107QM5	aconitate hydratase
BTL48_13085	ENOG4105CD3	dihydroorotase
BTL48_13090	ENOG4108UAU	isochorismatase
BTL48_13095	ENOG4105CKI	cobalamin synthesis protein
BTL48_13125	ENOG4105CC0	LysR family Transcriptional regulator
BTL48_13135	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BTL48_13140	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
BTL48_13145	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BTL48_13160	ENOG4105CMM	transposase
BTL48_13185	ENOG4107HP6	Transcriptional regulator
BTL48_13205	ENOG4105C1J	atp-dependent rna helicase
BTL48_13230	ENOG4105DNZ	Alpha Beta Hydrolase
BTL48_13235	ENOG4105ERG	peptidase m48, ste24p
BTL48_13260	ENOG4105CMM	transposase
BTL48_13275	ENOG4107RAQ	aminopeptidase
BTL48_13285	ENOG4105D0A	hydroxylase
BTL48_13295	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BTL48_13310	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BTL48_13315	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BTL48_13330	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BTL48_13335	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BTL48_13345	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BTL48_13355	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BTL48_13365	ENOG4105CX6	glutaminyL-tRNA synthetase
BTL48_13370	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BTL48_13375	ENOG4107QMS	site-determining protein
BTL48_13380	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BTL48_13400	ENOG4105C5H	ABC transporter
BTL48_13415	ENOG4108JQ7	(ABC) transporter
BTL48_13420	ENOG4105C3U	ABC transporter
BTL48_13425	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BTL48_13440	ENOG4108SHN	Glycosyl transferase, family 2
BTL48_13445	ENOG4105CR8	Transcriptional regulator
BTL48_13450	ENOG4105E0M	Sulfatase
BTL48_13475	ENOG4105DQ4	alcohol dehydrogenase
BTL48_13485	ENOG4108ZXC	Two component transcriptional regulator, luxr family
BTL48_13495	ENOG4105DRR	Transcriptional regulator, GntR family
BTL48_13525	ENOG4105C1J	atp-dependent rna helicase
BTL48_13530	ENOG4105D8X	mechanosensitive ion channel
BTL48_13545	ENOG4108SF5	RNA Polymerase
BTL48_13585	ENOG4105CC0	LysR family Transcriptional regulator
BTL48_13590	ENOG4105D5Q	Arginine ornithine antiporter
BTL48_13595	ENOG4105CXN	decarboxylase
BTL48_13615	ENOG4105CMM	transposase
BTL48_13620	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BTL48_13625	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BTL48_13635	ENOG41080IJ	Diacylglycerol kinase
BTL48_13640	ENOG4105CEP	NADH dehydrogenase
BTL48_13645	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
BTL48_13655	ENOG4108ZAI	phosphatidylglycerophosphatase a
BTL48_13660	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BTL48_13665	ENOG4107YIM	Involved in the transcription termination process (By similarity)
BTL48_13670	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BTL48_13700	ENOG4108SF5	RNA Polymerase
BTL48_13710	ENOG4105D5T	phosphonate abc transporter
BTL48_13735	ENOG4106H78	methyltransferase
BTL48_13740	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BTL48_13745	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
BTL48_13750	ENOG4105DKK	Benzoate
BTL48_13770	ENOG4105E0K	tonB-dependent siderophore receptor
BTL48_13795	ENOG4105E39	Enoyl-CoA hydratase
BTL48_13800	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
BTL48_13805	ENOG4105C1G	acyl-Coa dehydrogenase
BTL48_13815	ENOG4105CEY	Amp-dependent synthetase and ligase
BTL48_13825	ENOG4105EBR	Carboxylesterase
BTL48_13830	ENOG4105DND	Transcriptional regulator
BTL48_13845	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
BTL48_13855	ENOG4105CQB	FAD linked oxidase domain protein
BTL48_13875	ENOG4105G3Z	GntR family transcriptional regulator
BTL48_13885	ENOG4105CSP	Major Facilitator Superfamily
BTL48_13920	ENOG4105C3G	gtp-binding protein
BTL48_13930	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BTL48_13935	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BTL48_13940	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BTL48_13950	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BTL48_13955	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
BTL48_13960	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
BTL48_13965	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BTL48_13995	ENOG4105F1J	Homogentisate 1,2-dioxygenase
BTL48_14005	ENOG4105E0M	Sulfatase
BTL48_14010	ENOG4107YCY	Transcriptional regulator
BTL48_14035	ENOG4105CQB	FAD linked oxidase domain protein
BTL48_14050	ENOG4107QP8	phosphohexose isomerase
BTL48_14055	ENOG4105CGN	Glycosyl transferase (Group 1
BTL48_14060	ENOG4105JNK	Glycosyl transferase (Group 1
BTL48_14065	ENOG4107XU6	Glycosyl transferase (Group 1
BTL48_14075	ENOG4105CG5	Glycosyl transferase (Group 1
BTL48_14090	ENOG4107QQG	Dehydrogenase
BTL48_14095	ENOG4107UKG	Glycosyl transferase, family 4
BTL48_14105	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
BTL48_14115	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BTL48_14125	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BTL48_14130	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BTL48_14135	ENOG4105C26	Dehydrogenase
BTL48_14160	ENOG4108JQ6	ABC transporter
BTL48_14180	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTL48_14185	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BTL48_14190	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BTL48_14195	ENOG4105CBX	hi0933 family
BTL48_14200	ENOG4105CXN	decarboxylase
BTL48_14210	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
BTL48_14215	ENOG4105DHP	deoxycytidine triphosphate deaminase
BTL48_14240	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BTL48_14275	ENOG4105ECM	Sensor protein basS pmrB
BTL48_14280	ENOG4105ETX	regulatoR
BTL48_14300	ENOG4105EHG	Permease protein
BTL48_14305	ENOG41090JD	Blue (Type 1) copper domain protein
BTL48_14320	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BTL48_14325	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
BTL48_14350	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BTL48_14355	ENOG4108Z9W	Outer membrane porin
BTL48_14360	ENOG4105D2B	acyl-CoA dehydrogenase
BTL48_14370	ENOG4105DND	Transcriptional regulator
BTL48_14380	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BTL48_14385	ENOG4105E39	Enoyl-CoA hydratase
BTL48_14400	ENOG4107NQ8	LysR family Transcriptional regulator
BTL48_14405	ENOG4105DIN	metallophosphoesterase
BTL48_14410	ENOG4105CYM	Glutathione S-transferase
BTL48_14425	ENOG4105CSW	GntR family transcriptional regulator
BTL48_14440	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
BTL48_14445	ENOG4105CNW	domain protein
BTL48_14455	ENOG4105CC0	LysR family Transcriptional regulator
BTL48_14465	ENOG4105E39	Enoyl-CoA hydratase
BTL48_14470	ENOG4105CD5	CoA-binding domain protein
BTL48_14475	ENOG4105CC9	acyl-Coa dehydrogenase
BTL48_14480	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BTL48_14485	ENOG4105CHR	reductase
BTL48_14505	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
BTL48_14550	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
BTL48_14555	ENOG4107RSM	transcriptional regulator
BTL48_14560	ENOG4105CSU	acyl-Coa dehydrogenase
BTL48_14570	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BTL48_14575	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BTL48_14585	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BTL48_14595	ENOG4105CMM	transposase
BTL48_14600	ENOG4105EAC	phosphoserine phosphatase
BTL48_14605	ENOG4105ETT	transcriptional Regulator, LysR family
BTL48_14615	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BTL48_14630	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTL48_14650	ENOG4108TGY	Glutathione S-transferase
BTL48_14655	ENOG4108IV0	ABC, transporter
BTL48_14660	ENOG4105C0Z	ABC transporter
BTL48_14680	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_14690	ENOG4105CFM	UPF0317 protein
BTL48_14695	ENOG4108MP6	LysR family Transcriptional regulator
BTL48_14700	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BTL48_14705	ENOG4105C2W	permease
BTL48_14725	ENOG4105CMM	transposase
BTL48_14745	ENOG4108R3E	Dna-3-methyladenine glycosylase i
BTL48_14750	ENOG4105PI0	Ferredoxin
BTL48_14775	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BTL48_14785	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BTL48_14790	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BTL48_14795	ENOG41084CK	capsule polysaccharide
BTL48_14815	ENOG4105CMM	transposase
BTL48_14845	ENOG4105D01	(LipO)protein
BTL48_14850	ENOG4108UMI	ABC transporter, permease
BTL48_14855	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BTL48_14860	ENOG4105CJQ	hydrolase, family 31
BTL48_14865	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
BTL48_14875	ENOG4105CEY	Amp-dependent synthetase and ligase
BTL48_14880	ENOG4105CH2	amidohydrolase
BTL48_14890	ENOG4105HMI	Membrane
BTL48_14895	ENOG4105NAU	thioesterase Superfamily protein
BTL48_14900	ENOG4105CJW	magnesium transporter
BTL48_14915	ENOG4108XM1	transcriptional regulator AsnC family
BTL48_14955	ENOG4105EPW	hflc protein
BTL48_14960	ENOG4107QJR	hflk protein
BTL48_14965	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BTL48_14970	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BTL48_14980	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BTL48_14985	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BTL48_14990	ENOG4105N21	Membrane
BTL48_14995	ENOG4105CUT	histidyl-tRNA synthetase
BTL48_15000	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BTL48_15010	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BTL48_15015	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BTL48_15020	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BTL48_15030	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BTL48_15035	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BTL48_15040	ENOG4105K5M	30s ribosomal protein S16
BTL48_15045	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
BTL48_15050	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BTL48_15100	ENOG4105CMM	transposase
BTL48_15115	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BTL48_15120	ENOG4108EX3	reductase
BTL48_15125	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BTL48_15130	ENOG4105KPY	Small multidrug resistance protein
BTL48_15135	ENOG4105QVC	MOSC domain-containing protein
BTL48_15140	ENOG4105EV8	ectoine hydroxylase
BTL48_15145	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
BTL48_15150	ENOG4108JPW	Aminotransferase
BTL48_15155	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
BTL48_15175	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BTL48_15185	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BTL48_15195	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BTL48_15200	ENOG4105K63	Thioredoxin
BTL48_15205	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BTL48_15215	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BTL48_15220	ENOG4105WPN	DNA integration recombination invertion protein
BTL48_15225	ENOG4105EJQ	L-serine dehydratase
BTL48_15230	ENOG4105EAM	Na Pi-cotransporter
BTL48_15235	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
BTL48_15240	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
BTL48_15245	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
BTL48_15255	ENOG4105E2S	oxidase) subunit II
BTL48_15260	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BTL48_15265	ENOG4105CCU	oxidase (Subunit III)
BTL48_15270	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
BTL48_15280	ENOG4105C2M	dna polymerase I
BTL48_15285	ENOG4108URH	decarboxylase
BTL48_15310	ENOG4108IJ7	Glycine betaine
BTL48_15315	ENOG4108HQS	Glycine betaine
BTL48_15330	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BTL48_15335	ENOG4105C2C	drug resistance transporter, Bcr CflA
BTL48_15340	ENOG4105KDC	50s ribosomal protein l28
BTL48_15345	ENOG4105W0E	50S ribosomal protein L33
BTL48_15370	ENOG4108VHT	MarR family transcriptional regulator
BTL48_15380	ENOG4105C8T	Leucyl-tRNA synthetase
BTL48_15395	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BTL48_15420	ENOG4108JJA	ABC, transporter
BTL48_15435	ENOG4105CMM	transposase
BTL48_15465	ENOG4105CYC	Transferase
BTL48_15475	ENOG4105EGS	Mechanosensitive ion channel
BTL48_15480	ENOG4105P69	integral membrane protein
BTL48_15485	ENOG4108594	Permease of the drug metabolite transporter
BTL48_15495	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BTL48_15500	ENOG4107QIJ	Aconitate hydratase 2
BTL48_15515	ENOG4107QM5	aconitate hydratase
BTL48_15520	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
BTL48_15535	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BTL48_15550	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BTL48_15560	ENOG4105CMM	transposase
BTL48_15660	ENOG4107QSI	ABC, transporter
BTL48_15685	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
BTL48_15690	ENOG4105EGI	Transcriptional regulator
BTL48_15695	ENOG4105EA8	2-Nitropropane dioxygenase
BTL48_15700	ENOG4105EA8	2-Nitropropane dioxygenase
BTL48_15710	ENOG4105CY2	Citrate transporter
BTL48_15715	ENOG4105E8G	Major facilitator Superfamily
BTL48_15725	ENOG4107RN3	metallophosphoesterase
BTL48_15730	ENOG4105BZ8	glutamate synthase
BTL48_15735	ENOG4105BZU	Histidine kinase
BTL48_15740	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BTL48_15745	ENOG4105C5Q	Transcriptional regulator
BTL48_15765	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
BTL48_15775	ENOG4105KHM	amidohydrolase 2
BTL48_15785	ENOG4107F9Y	LysR family transcriptional regulator
BTL48_15790	ENOG4105GAK	amidohydrolase 2
BTL48_15800	ENOG4105E39	Enoyl-CoA hydratase
BTL48_15805	ENOG4105JXH	GntR family transcriptional regulator
BTL48_15810	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
BTL48_15820	ENOG4108IQI	permease
BTL48_15825	ENOG4107QMS	site-determining protein
BTL48_15830	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BTL48_15850	ENOG4108JJ7	ABC transporter
BTL48_15890	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
BTL48_15895	ENOG4108MEJ	flavin reductase domain protein
BTL48_15905	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BTL48_15910	ENOG4105C2C	drug resistance transporter, Bcr CflA
BTL48_15930	ENOG4105S66	prophage protein
BTL48_15955	ENOG4105F76	Sarcosine oxidase
BTL48_15980	ENOG4105DEF	Extracellular solute-binding protein, family 5
BTL48_15990	ENOG4105CYM	Glutathione S-transferase
BTL48_16020	ENOG4108SF5	RNA Polymerase
BTL48_16045	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
BTL48_16060	ENOG4108IY8	ABC, transporter
BTL48_16065	ENOG4107T0D	ABC, transporter
BTL48_16090	ENOG410846T	CoA-transferase family III
BTL48_16095	ENOG4105E39	Enoyl-CoA hydratase
BTL48_16130	ENOG4105DG7	nitrate ABC transporter
BTL48_16135	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BTL48_16140	ENOG4105E2Y	ABC, transporter
BTL48_16145	ENOG4105CPU	Monooxygenase
BTL48_16150	ENOG4105X1Q	TOBE domain protein
BTL48_16160	ENOG4108IV0	ABC, transporter
BTL48_16165	ENOG4105C0Z	ABC transporter
BTL48_16170	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BTL48_16210	ENOG4105CXK	mandelate racemase muconate lactonizing
BTL48_16275	ENOG4105C32	Amino acid ABC transporter (Permease)
BTL48_16280	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BTL48_16285	ENOG4105C0Z	ABC transporter
BTL48_16290	ENOG4108IV0	ABC, transporter
BTL48_16305	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BTL48_16320	ENOG4105CUZ	uba thif-type nad fad binding protein
BTL48_16325	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BTL48_16330	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BTL48_16335	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
BTL48_16350	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BTL48_16360	ENOG4105D5U	fad dependent oxidoreductase
BTL48_16370	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BTL48_16390	ENOG4105C9Q	fumarate hydratase class II
BTL48_16395	ENOG4105K8N	protein family UPF0079, ATPase
BTL48_16400	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BTL48_16405	ENOG4105DQR	SNARE associated Golgi
BTL48_16410	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BTL48_16415	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BTL48_16420	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BTL48_16425	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
BTL48_16435	ENOG4105DJ0	Poly(A) Polymerase
BTL48_16440	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTL48_16455	ENOG4105CMM	transposase
BTL48_16475	ENOG4108M9J	MaoC like domain protein
BTL48_16495	ENOG4108TZY	GntR Family Transcriptional Regulator
BTL48_16500	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BTL48_16515	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
BTL48_16520	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
BTL48_16525	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
BTL48_16530	ENOG4105E9Q	Acyl-transferase
BTL48_16560	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BTL48_16575	ENOG4105CA9	Pyruvate kinase
BTL48_16580	ENOG4105BZW	Glycerate kinase
BTL48_16590	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BTL48_16595	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BTL48_16600	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
BTL48_16605	ENOG4105EHM	Aminoglycoside phosphotransferase
BTL48_16610	ENOG4108S0S	Nucleotidyl transferase
BTL48_16620	ENOG4105KZX	Pterin carbinolamine dehydratase
BTL48_16625	ENOG4108ZG0	Ompa motb domain protein
BTL48_16635	ENOG4105CPC	Aldo Keto reductase
BTL48_16650	ENOG4105CMM	transposase
BTL48_16665	ENOG4107RZC	phospholipase d
BTL48_16670	ENOG4107B2H	carbonic anhydrase
BTL48_16690	ENOG4105F2Z	3-oxoadipate enol-lactonase
BTL48_16700	ENOG4105NN7	muconolactone delta-isomerase
BTL48_16705	ENOG4107QNJ	CoA-transferase subunit B
BTL48_16710	ENOG4107QP7	CoA-transferase subunit A
BTL48_16715	ENOG4107HP6	Transcriptional regulator
BTL48_16720	ENOG4105CHR	reductase
BTL48_16725	ENOG4105CRW	Short chain fatty acid transporter
BTL48_16730	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BTL48_16740	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BTL48_16745	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BTL48_16755	ENOG4105DUM	transcriptional regulator, lysR family
BTL48_16760	ENOG4105C01	Dihydroxy-acid dehydratase
BTL48_16765	ENOG4105K2J	Transcriptional regulator
BTL48_16785	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
BTL48_16805	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
BTL48_16830	ENOG4105CMM	transposase
BTL48_16840	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
BTL48_16850	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BTL48_16855	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BTL48_16860	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BTL48_16875	ENOG4108S3W	Anti-feci sigma factor, fecr
BTL48_16890	ENOG4105BZS	acriflavin resistance protein
BTL48_16905	ENOG4105CHH	sulfate transporter
BTL48_16920	ENOG4105D2S	major facilitator superfamily
BTL48_16925	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
BTL48_16940	ENOG4105E0K	tonB-dependent siderophore receptor
BTL48_16950	ENOG4108SF5	RNA Polymerase
BTL48_16965	ENOG4105EAH	synthase
BTL48_16970	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BTL48_16975	ENOG4105K46	50S ribosomal protein l27
BTL48_16980	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BTL48_16985	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BTL48_17005	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BTL48_17010	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BTL48_17020	ENOG41063Z6	transcriptional regulator, lysR family
BTL48_17040	ENOG4105D06	uba thif-type nad fad binding protein
BTL48_17045	ENOG4105CN1	protease
BTL48_17050	ENOG41063SB	peptidase
BTL48_17055	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BTL48_17065	ENOG4105VW4	glutaredoxin 3
BTL48_17070	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
BTL48_17075	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BTL48_17095	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BTL48_17100	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
BTL48_17105	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
BTL48_17115	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BTL48_17120	ENOG4105ES5	Histidine kinase
BTL48_17130	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BTL48_17140	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
BTL48_17150	ENOG4105CHR	reductase
BTL48_17165	ENOG4105FDP	GntR family transcriptional regulator
BTL48_17180	ENOG4105DUM	transcriptional regulator, lysR family
BTL48_17185	ENOG4105C26	Dehydrogenase
BTL48_17205	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
BTL48_17220	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BTL48_17225	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BTL48_17235	ENOG4105F7P	transcriptional regulator AsnC family
BTL48_17240	ENOG4105VCD	cytoplasmic protein
BTL48_17245	ENOG4105D22	carbon starvation protein
BTL48_17265	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
BTL48_17275	ENOG4107QXX	ABC transporter
BTL48_17280	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BTL48_17285	ENOG4105DFA	alanine racemase domain protein
BTL48_17315	ENOG4108MGI	Transcriptional regulator
BTL48_17320	ENOG4105CP9	extracellular ligand-binding receptor
BTL48_17330	ENOG4105C0Z	ABC transporter
BTL48_17335	ENOG4108IV0	ABC, transporter
BTL48_17355	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
BTL48_17370	ENOG4108IV0	ABC, transporter
BTL48_17375	ENOG4105DZS	Phenylacetate-CoA ligase
BTL48_17390	ENOG41080HT	Transcriptional regulator, arsr family
BTL48_17420	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BTL48_17430	ENOG41090R7	Ferric uptake
BTL48_17435	ENOG4105R1U	AraC Family Transcriptional Regulator
BTL48_17440	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BTL48_17445	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BTL48_17450	ENOG4105C1J	atp-dependent rna helicase
BTL48_17470	ENOG4107SC1	transglycosylase
BTL48_17475	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BTL48_17515	ENOG4105E18	UPF0276 protein
BTL48_17530	ENOG4105SYT	Methylenetetrahydrofolate reductase
BTL48_17535	ENOG41082T9	Membrane
BTL48_17540	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BTL48_17560	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BTL48_17565	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BTL48_17575	ENOG4105D1S	lipid A biosynthesis
BTL48_17580	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BTL48_17590	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BTL48_17595	ENOG4105UGU	tonB-dependent Receptor
BTL48_17610	ENOG4108XAN	ABC transporter
BTL48_17615	ENOG4105CC5	ABC transporter
BTL48_17620	ENOG4105DIK	(ABC) transporter
BTL48_17625	ENOG4105MYN	Zinc uptake regulation protein
BTL48_17630	ENOG4105CKI	cobalamin synthesis protein
BTL48_17635	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTL48_17640	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BTL48_17645	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BTL48_17655	ENOG4108WBT	adenosyltransferase
BTL48_17660	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BTL48_17665	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BTL48_17675	ENOG4105F0I	Aminotransferase
BTL48_17680	ENOG4105DZ1	carboxypeptidase
BTL48_17715	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BTL48_17720	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
BTL48_17725	ENOG4105D16	lipopolysaccharide heptosyltransferase i
BTL48_17730	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BTL48_17735	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
BTL48_17740	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BTL48_17745	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BTL48_17760	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BTL48_17770	ENOG4105DZQ	phospholipase D Transphosphatidylase
BTL48_17775	ENOG4105X23	Endonuclease Exonuclease phosphatase
BTL48_17780	ENOG4105C9M	aspartyl-trna synthetase
BTL48_17810	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BTL48_17815	ENOG4108ZGC	gaf domain protein
BTL48_17820	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BTL48_17835	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
BTL48_17840	ENOG4107QP3	malate synthase g
BTL48_17855	ENOG4105C4Y	ABC transporter
BTL48_17860	ENOG4105DHQ	Histidine kinase
BTL48_17865	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BTL48_17875	ENOG4105J5G	Transferase hexapeptide repeat containing protein
BTL48_17885	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BTL48_17895	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BTL48_17920	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BTL48_17945	ENOG4105CHR	reductase
BTL48_17950	ENOG4105C26	Dehydrogenase
BTL48_17955	ENOG4105CMM	transposase
BTL48_17975	ENOG4108YXU	transcriptional regulator AsnC family
BTL48_17980	ENOG4105FFC	UPF0187 protein
BTL48_17995	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BTL48_18025	ENOG4105BZU	Histidine kinase
BTL48_18030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BTL48_18035	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BTL48_18040	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BTL48_18045	ENOG4105VG0	50S ribosomal protein l34
BTL48_18050	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BTL48_18055	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BTL48_18060	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BTL48_18065	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BTL48_18070	ENOG4105CH2	amidohydrolase
BTL48_18075	ENOG4108JQ7	(ABC) transporter
BTL48_18080	ENOG4105C3U	ABC transporter
BTL48_18085	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BTL48_18090	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BTL48_18100	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BTL48_18115	ENOG4105C6K	Malic enzyme
BTL48_18125	ENOG4105GR3	Histidine kinase
BTL48_18145	ENOG4105CHM	Aminotransferase
BTL48_18150	ENOG4105VEQ	Cold shock protein
