locus-tag	class	description
BTL48_00005	COG0445	tRNA wobble uridine modification
BTL48_00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BTL48_00015	COG1192	Involved in chromosome partitioning
BTL48_00020	COG1475	DNA binding
BTL48_00025	COG0252	asparaginase activity
BTL48_00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTL48_00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTL48_00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTL48_00070	COG0081	regulation of translation
BTL48_00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BTL48_00080	COG0222	ribosome binding
BTL48_00085	COG0085	RNA polymerase activity
BTL48_00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BTL48_00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTL48_00130	COG0049	tRNA binding
BTL48_00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTL48_00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTL48_00145	COG0051	transcription antitermination factor activity, RNA binding
BTL48_00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTL48_00155	COG0088	Forms part of the polypeptide exit tunnel
BTL48_00160	COG0089	rRNA binding
BTL48_00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BTL48_00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BTL48_00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BTL48_00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BTL48_00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BTL48_00190	COG0255	Belongs to the universal ribosomal protein uL29 family
BTL48_00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BTL48_00210	COG0410	ABC transporter
BTL48_00215	COG1129	ABC transporter
BTL48_00220	COG0411	ABC transporter
BTL48_00250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BTL48_00255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BTL48_00260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BTL48_00265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BTL48_00270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BTL48_00275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BTL48_00280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BTL48_00285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BTL48_00290	COG1841	ribosomal large subunit assembly
BTL48_00295	COG0200	Binds to the 23S rRNA
BTL48_00300	COG0201	protein transport
BTL48_00305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTL48_00310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTL48_00315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTL48_00320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BTL48_00325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BTL48_00330	COG0202	RNA polymerase activity
BTL48_00335	COG0203	ribosomal protein L17
BTL48_00340	COG0537	adenosine 5'-monophosphoramidase activity
BTL48_00345	COG1324	tolerance protein
BTL48_00350	COG4232	protein-disulfide reductase activity
BTL48_00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BTL48_00375	COG1333	cytochrome c biogenesis protein
BTL48_00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTL48_00395	COG1965	Belongs to the frataxin family
BTL48_00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTL48_00410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTL48_00415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BTL48_00435	COG2814	Major facilitator Superfamily
BTL48_00450	COG2801	Transposase and inactivated derivatives
BTL48_00495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL48_00500	COG2922	Belongs to the Smg family
BTL48_00525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTL48_00540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTL48_00545	COG0183	Belongs to the thiolase family
BTL48_00550	COG1960	acyl-CoA dehydrogenase activity
BTL48_00575	COG2200	EAL domain
BTL48_00580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTL48_00590	COG0018	arginyl-trna synthetase
BTL48_00605	COG0154	amidase activity
BTL48_00610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL48_00620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTL48_00630	COG0697	spore germination
BTL48_00660	COG2151	metal-sulfur cluster biosynthetic enzyme
BTL48_00720	COG1309	transcriptional regulator
BTL48_00750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BTL48_00755	COG1280	lysine exporter protein (LysE YggA)
BTL48_00760	COG0513	Belongs to the DEAD box helicase family
BTL48_00770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BTL48_00775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BTL48_00805	COG2969	positive regulation of protein catabolic process
BTL48_00810	COG0625	glutathione transferase activity
BTL48_00815	COG2857	Cytochrome c1
BTL48_00820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTL48_00825	COG0723	plastoquinol--plastocyanin reductase activity
BTL48_00830	COG1970	mechanosensitive ion channel activity
BTL48_00835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTL48_00840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTL48_00850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTL48_00855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTL48_00865	COG0140	phosphoribosyl-ATP diphosphatase activity
BTL48_00870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BTL48_00875	COG0107	imidazoleglycerol-phosphate synthase activity
BTL48_00880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BTL48_00885	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BTL48_00890	COG0131	Imidazoleglycerol-phosphate dehydratase
BTL48_00895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTL48_00900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BTL48_00905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BTL48_00910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTL48_00920	COG0842	Transport permease protein
BTL48_00925	COG1131	(ABC) transporter
BTL48_00940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BTL48_00945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTL48_00950	COG1127	ABC transporter
BTL48_00970	COG0069	glutamate synthase activity
BTL48_00970	COG0070	glutamate synthase
BTL48_00970	COG0067	glutamate synthase
BTL48_00990	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BTL48_01010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTL48_01015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BTL48_01035	COG2801	Transposase and inactivated derivatives
BTL48_01055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL48_01090	COG0109	protoheme IX farnesyltransferase activity
BTL48_01095	COG1999	signal sequence binding
BTL48_01115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BTL48_01120	COG2814	Major facilitator Superfamily
BTL48_01135	COG1522	sequence-specific DNA binding
BTL48_01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BTL48_01185	COG4948	Mandelate Racemase Muconate Lactonizing
BTL48_01200	COG3119	arylsulfatase activity
BTL48_01220	COG2801	Transposase and inactivated derivatives
BTL48_01240	COG0402	S-adenosylhomocysteine deaminase activity
BTL48_01250	COG1304	FMN binding
BTL48_01255	COG1254	Belongs to the acylphosphatase family
BTL48_01265	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_01275	COG1414	Transcriptional regulator
BTL48_01285	COG2801	Transposase and inactivated derivatives
BTL48_01295	COG0028	Belongs to the TPP enzyme family
BTL48_01300	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BTL48_01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_01310	COG1960	acyl-CoA dehydrogenase activity
BTL48_01345	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_01350	COG0583	DNA-binding transcription factor activity
BTL48_01365	COG0129	dihydroxy-acid dehydratase activity
BTL48_01370	COG2084	Dehydrogenase
BTL48_01385	COG1671	Belongs to the UPF0178 family
BTL48_01390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL48_01400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BTL48_01405	COG0443	Heat shock 70 kDa protein
BTL48_01430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTL48_01430	COG2169	Transcriptional regulator
BTL48_01445	COG1683	Conserved Protein
BTL48_01450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL48_01465	COG1120	ATPase activity
BTL48_01470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTL48_01475	COG4558	Periplasmic binding protein
BTL48_01480	COG3720	iron ion transport
BTL48_01490	COG3712	iron ion homeostasis
BTL48_01495	COG1595	DNA-templated transcription, initiation
BTL48_01515	COG1607	acyl-coa hydrolase
BTL48_01525	COG0243	molybdopterin cofactor binding
BTL48_01525	COG3383	formate dehydrogenase (NAD+) activity
BTL48_01530	COG0243	molybdopterin cofactor binding
BTL48_01530	COG3383	formate dehydrogenase (NAD+) activity
BTL48_01535	COG0437	4 iron, 4 sulfur cluster binding
BTL48_01540	COG2864	formate dehydrogenase
BTL48_01555	COG3276	selenocysteine insertion sequence binding
BTL48_01585	COG0134	indole-3-glycerol-phosphate synthase activity
BTL48_01590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTL48_01595	COG0512	Glutamine amidotransferase of anthranilate synthase
BTL48_01605	COG0546	phosphoglycolate phosphatase activity
BTL48_01615	COG2967	ApaG domain
BTL48_01620	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BTL48_01625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL48_01630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTL48_01635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL48_01640	COG0037	tRNA processing
BTL48_01660	COG1024	Enoyl-CoA hydratase
BTL48_01675	COG0356	it plays a direct role in the translocation of protons across the membrane
BTL48_01685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BTL48_01690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BTL48_01695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BTL48_01700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BTL48_01705	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BTL48_01710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BTL48_01735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BTL48_01740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTL48_01745	COG0210	DNA helicase
BTL48_01760	COG4608	Belongs to the ABC transporter superfamily
BTL48_01765	COG0444	Belongs to the ABC transporter superfamily
BTL48_01770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL48_01795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BTL48_01800	COG1024	Enoyl-CoA hydratase
BTL48_01805	COG1024	Enoyl-CoA hydratase
BTL48_01810	COG2070	2-Nitropropane dioxygenase
BTL48_01825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_01830	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL48_01845	COG2918	glutathione biosynthetic process
BTL48_01850	COG2267	carboxylic ester hydrolase activity
BTL48_01870	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BTL48_01875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL48_01880	COG2813	Specifically methylates the guanine in position
BTL48_01880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL48_01885	COG2223	nitrite transmembrane transporter activity
BTL48_01890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL48_01905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTL48_01910	COG0708	Exodeoxyribonuclease III
BTL48_01915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BTL48_01920	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTL48_01925	COG0154	amidase activity
BTL48_01930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTL48_01935	COG1077	Cell shape determining protein MreB Mrl
BTL48_01940	COG1792	Involved in formation and maintenance of cell shape
BTL48_01950	COG0768	penicillin binding
BTL48_01955	COG0772	Belongs to the SEDS family
BTL48_01960	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BTL48_01965	COG0471	metal ion transport
BTL48_01970	COG1309	transcriptional regulator
BTL48_01980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTL48_01995	COG2823	Periplasmic or secreted lipoprotein
BTL48_02000	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BTL48_02005	COG0792	nuclease activity
BTL48_02025	COG1660	Displays ATPase and GTPase activities
BTL48_02040	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BTL48_02050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTL48_02060	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_02065	COG1473	amidohydrolase
BTL48_02070	COG1137	ATPase activity
BTL48_02085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BTL48_02095	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BTL48_02115	COG1294	oxidase, subunit
BTL48_02125	COG4988	ABC transporter
BTL48_02130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTL48_02135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTL48_02150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTL48_02155	COG1238	metal cluster binding
BTL48_02170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BTL48_02175	COG1984	allophanate hydrolase subunit 2
BTL48_02180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTL48_02190	COG0583	DNA-binding transcription factor activity
BTL48_02195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL48_02200	COG5002	protein histidine kinase activity
BTL48_02205	COG0745	RESPONSE REGULATOR receiver
BTL48_02210	COG2226	methyltransferase
BTL48_02245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTL48_02255	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_02275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTL48_02280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTL48_02290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTL48_02315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BTL48_02320	COG1538	Outer membrane efflux protein
BTL48_02330	COG0351	phosphomethylpyrimidine kinase
BTL48_02335	COG2022	thiamine diphosphate biosynthetic process
BTL48_02340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTL48_02360	COG2226	methyltransferase
BTL48_02370	COG1194	a g-specific adenine glycosylase
BTL48_02380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BTL48_02385	COG2177	Part of the ABC transporter FtsEX involved in
BTL48_02390	COG2884	Cell division ATP-binding protein ftsE
BTL48_02395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL48_02400	COG4597	amino acid ABC transporter
BTL48_02405	COG0765	amino acid transport
BTL48_02410	COG1126	abc transporter atp-binding protein
BTL48_02425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BTL48_02440	COG0477	Major facilitator Superfamily
BTL48_02450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BTL48_02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BTL48_02470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTL48_02475	COG0237	dephospho-CoA kinase activity
BTL48_02480	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BTL48_02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTL48_02505	COG3539	Fimbrial protein
BTL48_02510	COG3539	Fimbrial protein
BTL48_02525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BTL48_02535	COG1846	Transcriptional regulator
BTL48_02565	COG0410	ABC transporter
BTL48_02590	COG3706	GGDEF domain
BTL48_02600	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_02605	COG1024	Enoyl-CoA hydratase
BTL48_02610	COG1960	acyl-CoA dehydrogenase activity
BTL48_02640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BTL48_02645	COG0352	thiamine-phosphate diphosphorylase activity
BTL48_02650	COG0351	phosphomethylpyrimidine kinase
BTL48_02660	COG1678	Uncharacterized ACR, COG1678
BTL48_02665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BTL48_02690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTL48_02700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTL48_02705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTL48_02715	COG0557	exoribonuclease II activity
BTL48_02725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTL48_02730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL48_02735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BTL48_02745	COG0439	Biotin carboxylase
BTL48_02750	COG2264	protein methyltransferase activity
BTL48_02780	COG1696	Membrane protein involved in D-alanine export
BTL48_02785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTL48_02825	COG1522	sequence-specific DNA binding
BTL48_02840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL48_02855	COG0411	ABC transporter
BTL48_02900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTL48_02925	COG3028	Belongs to the UPF0307 family
BTL48_02930	COG0312	modulator of DNA gyrase
BTL48_02935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BTL48_02940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BTL48_02945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTL48_02955	COG0316	Belongs to the HesB IscA family
BTL48_02965	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BTL48_02975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTL48_02980	COG1881	PFAM PEBP family protein
BTL48_02985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BTL48_02990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTL48_03005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTL48_03005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTL48_03020	COG2718	Belongs to the UPF0229 family
BTL48_03025	COG2719	SpoVR family
BTL48_03070	COG0477	Major facilitator Superfamily
BTL48_03085	COG0165	Argininosuccinate lyase
BTL48_03090	COG0589	response to stress
BTL48_03100	COG2816	NAD+ diphosphatase activity
BTL48_03105	COG4993	Dehydrogenase
BTL48_03130	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_03135	COG2979	Protein of unknown function (DUF533)
BTL48_03140	COG4206	TonB-dependent receptor
BTL48_03155	COG1388	LysM domain
BTL48_03155	COG0741	lytic transglycosylase activity
BTL48_03160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTL48_03165	COG2226	methyltransferase
BTL48_03170	COG0328	RNA-DNA hybrid ribonuclease activity
BTL48_03195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTL48_03210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL48_03215	COG0842	Transport permease protein
BTL48_03215	COG1129	ABC transporter
BTL48_03220	COG0842	Transport permease protein
BTL48_03235	COG0463	Glycosyl transferase, family 2
BTL48_03240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BTL48_03255	COG1073	alpha beta
BTL48_03265	COG0697	spore germination
BTL48_03270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL48_03290	COG2801	Transposase and inactivated derivatives
BTL48_03295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTL48_03325	COG0823	Involved in the tonB-independent uptake of proteins
BTL48_03335	COG0848	biopolymer transport protein
BTL48_03340	COG0811	peptide transport
BTL48_03345	COG0824	Thioesterase
BTL48_03350	COG0442	prolyl-tRNA aminoacylation
BTL48_03390	COG2084	Dehydrogenase
BTL48_03430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BTL48_03435	COG4654	Cytochrome c, class I
BTL48_03440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTL48_03450	COG1522	sequence-specific DNA binding
BTL48_03490	COG2801	Transposase and inactivated derivatives
BTL48_03505	COG1473	amidohydrolase
BTL48_03510	COG0418	dihydroorotase activity
BTL48_03525	COG2001	Belongs to the MraZ family
BTL48_03530	COG0275	rRNA processing
BTL48_03535	COG3116	cell division
BTL48_03545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTL48_03550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTL48_03555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BTL48_03565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BTL48_03570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTL48_03575	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTL48_03580	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BTL48_03595	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BTL48_03610	COG0739	heme binding
BTL48_03615	COG0653	protein targeting
BTL48_03635	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BTL48_03640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTL48_03655	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTL48_03685	COG2801	Transposase and inactivated derivatives
BTL48_03695	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BTL48_03710	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BTL48_03735	COG0583	DNA-binding transcription factor activity
BTL48_03745	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_03750	COG2084	Dehydrogenase
BTL48_03760	COG1803	Methylglyoxal synthase
BTL48_03760	COG1597	lipid kinase activity
BTL48_03770	COG0671	phosphoesterase, PA-phosphatase related
BTL48_03790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL48_03795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL48_03800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL48_03805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL48_03810	COG0649	NAD binding
BTL48_03815	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BTL48_03825	COG1034	ATP synthesis coupled electron transport
BTL48_03830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BTL48_03835	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL48_03845	COG0713	ATP synthesis coupled electron transport
BTL48_03860	COG1007	ATP synthesis coupled electron transport
BTL48_03870	COG0560	Phosphoserine phosphatase
BTL48_03875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTL48_03880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BTL48_03885	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BTL48_03895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL48_03900	COG0450	alkyl hydroperoxide reductase
BTL48_03910	COG0745	RESPONSE REGULATOR receiver
BTL48_03920	COG1214	PFAM Peptidase M22, glycoprotease
BTL48_03925	COG1573	uracil-dna glycosylase
BTL48_03930	COG0477	Major facilitator Superfamily
BTL48_03935	COG1196	nuclear chromosome segregation
BTL48_03945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTL48_03950	COG1126	abc transporter atp-binding protein
BTL48_03955	COG0765	amino acid transport
BTL48_03960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL48_03965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL48_03975	COG2917	probably involved in intracellular septation
BTL48_03980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTL48_03985	COG1122	ATPase activity
BTL48_03990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTL48_04010	COG0411	ABC transporter
BTL48_04015	COG0410	ABC transporter
BTL48_04025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL48_04065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTL48_04070	COG2878	Part of a membrane complex involved in electron transport
BTL48_04090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTL48_04095	COG0251	oxidation-reduction process
BTL48_04105	COG3228	Belongs to the MtfA family
BTL48_04110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTL48_04120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTL48_04125	COG0133	tryptophan synthase activity
BTL48_04130	COG0159	tryptophan synthase activity
BTL48_04135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BTL48_04140	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTL48_04160	COG1530	ribonuclease E activity
BTL48_04165	COG0564	pseudouridine synthase activity
BTL48_04170	COG0546	phosphoglycolate phosphatase activity
BTL48_04175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTL48_04180	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BTL48_04185	COG3023	N-Acetylmuramoyl-L-alanine amidase
BTL48_04195	COG0424	maF-like protein
BTL48_04200	COG1399	metal-binding, possibly nucleic acid-binding protein
BTL48_04205	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTL48_04210	COG0416	fatty acid biosynthetic process
BTL48_04215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTL48_04225	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_04230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTL48_04235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTL48_04260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTL48_04275	COG0481	GTPase activity
BTL48_04280	COG0681	Belongs to the peptidase S26 family
BTL48_04285	COG0571	ribonuclease III activity
BTL48_04290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTL48_04295	COG1381	Involved in DNA repair and RecF pathway recombination
BTL48_04300	COG3706	GGDEF domain
BTL48_04300	COG0745	RESPONSE REGULATOR receiver
BTL48_04310	COG0670	Belongs to the BI1 family
BTL48_04325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BTL48_04350	COG0583	DNA-binding transcription factor activity
BTL48_04365	COG0791	NLP P60 protein
BTL48_04370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL48_04375	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BTL48_04385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL48_04400	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BTL48_04435	COG1446	asparaginase
BTL48_04440	COG4172	Belongs to the ABC transporter superfamily
BTL48_04445	COG0747	negative chemotaxis
BTL48_04450	COG0601	transmembrane transport
BTL48_04475	COG0504	CTP synthase activity
BTL48_04490	COG0148	phosphopyruvate hydratase activity
BTL48_04505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BTL48_04515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL48_04535	COG2801	Transposase and inactivated derivatives
BTL48_04580	COG0039	L-malate dehydrogenase activity
BTL48_04585	COG2188	Transcriptional regulator
BTL48_04590	COG2009	succinate dehydrogenase
BTL48_04595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BTL48_04600	COG1053	succinate dehydrogenase
BTL48_04605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTL48_04610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BTL48_04615	COG0372	Belongs to the citrate synthase family
BTL48_04625	COG0583	DNA-binding transcription factor activity
BTL48_04630	COG3842	ATPase activity
BTL48_04640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTL48_04645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTL48_04655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL48_04665	COG3128	pkhd-type hydroxylase
BTL48_04670	COG4774	siderophore transport
BTL48_04680	COG0281	malic enzyme
BTL48_04680	COG0280	phosphate acetyltransferase
BTL48_04690	COG1297	OPT oligopeptide transporter protein
BTL48_04695	COG0567	Dehydrogenase, E1 component
BTL48_04700	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTL48_04705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTL48_04710	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BTL48_04715	COG1595	DNA-templated transcription, initiation
BTL48_04725	COG4774	siderophore transport
BTL48_04745	COG0180	Tryptophanyl-tRNA synthetase
BTL48_04750	COG2183	response to ionizing radiation
BTL48_04755	COG1199	ATP-dependent helicase activity
BTL48_04765	COG0564	pseudouridine synthase activity
BTL48_04775	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTL48_04780	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_04785	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BTL48_04815	COG2823	Periplasmic or secreted lipoprotein
BTL48_04830	COG3237	CsbD-like
BTL48_04835	COG3038	cytochrome b561
BTL48_04850	COG1132	(ABC) transporter
BTL48_04865	COG2833	Protein of unknown function (DUF455)
BTL48_04870	COG2951	lytic endotransglycosylase activity
BTL48_04880	COG3706	GGDEF domain
BTL48_04880	COG0745	RESPONSE REGULATOR receiver
BTL48_04895	COG0586	Pfam SNARE associated Golgi protein
BTL48_04930	COG2801	Transposase and inactivated derivatives
BTL48_04950	COG0165	Argininosuccinate lyase
BTL48_04970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTL48_04985	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BTL48_04990	COG1605	Chorismate mutase
BTL48_04990	COG0077	Prephenate dehydratase
BTL48_05005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BTL48_05010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BTL48_05030	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BTL48_05035	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BTL48_05040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTL48_05045	COG0587	DNA-directed DNA polymerase activity
BTL48_05055	COG2951	lytic endotransglycosylase activity
BTL48_05060	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTL48_05075	COG2985	domain, Protein
BTL48_05080	COG1960	acyl-CoA dehydrogenase activity
BTL48_05085	COG0450	alkyl hydroperoxide reductase
BTL48_05090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BTL48_05095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BTL48_05100	COG4208	sulfate ABC transporter
BTL48_05110	COG0175	sulfate reduction
BTL48_05135	COG0335	large ribosomal subunit rRNA binding
BTL48_05150	COG3622	Belongs to the hyi family
BTL48_05155	COG1162	GTPase activity
BTL48_05160	COG0501	Belongs to the peptidase M48B family
BTL48_05165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BTL48_05170	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BTL48_05175	COG3327	negative regulation of DNA-templated transcription, initiation
BTL48_05180	COG3396	Phenylacetate-CoA oxygenase
BTL48_05185	COG3460	Phenylacetate-CoA oxygenase
BTL48_05190	COG3396	Phenylacetate-CoA oxygenase
BTL48_05195	COG2151	metal-sulfur cluster biosynthetic enzyme
BTL48_05200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL48_05205	COG1012	belongs to the aldehyde dehydrogenase family
BTL48_05210	COG1024	Enoyl-CoA hydratase
BTL48_05215	COG2050	protein possibly involved in aromatic compounds catabolism
BTL48_05255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL48_05260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BTL48_05265	COG2346	COG2346, Truncated hemoglobins
BTL48_05270	COG3642	lipopolysaccharide core region biosynthetic process
BTL48_05280	COG3842	ATPase activity
BTL48_05285	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTL48_05290	COG1177	transmembrane transport
BTL48_05310	COG1322	Protein conserved in bacteria
BTL48_05320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BTL48_05325	COG0704	Plays a role in the regulation of phosphate uptake
BTL48_05330	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BTL48_05335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTL48_05335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTL48_05340	COG1643	Atp-dependent helicase
BTL48_05355	COG0438	transferase activity, transferring glycosyl groups
BTL48_05360	COG0726	polysaccharide deacetylase
BTL48_05365	COG0463	Glycosyl transferase, family 2
BTL48_05400	COG1132	(ABC) transporter
BTL48_05425	COG0501	Belongs to the peptidase M48B family
BTL48_05470	COG1722	exodeoxyribonuclease VII activity
BTL48_05475	COG0142	geranyltranstransferase activity
BTL48_05480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BTL48_05485	COG1469	GTP cyclohydrolase I activity
BTL48_05490	COG0360	Binds together with S18 to 16S ribosomal RNA
BTL48_05495	COG2965	DNA replication, synthesis of RNA primer
BTL48_05500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BTL48_05505	COG0359	binds to the 23S rRNA
BTL48_05515	COG0305	Participates in initiation and elongation during chromosome replication
BTL48_05535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BTL48_05540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTL48_05545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTL48_05550	COG3737	Protein of unknown function (DUF498/DUF598)
BTL48_05555	COG0436	Aminotransferase
BTL48_05575	COG2801	Transposase and inactivated derivatives
BTL48_05580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BTL48_05585	COG0308	aminopeptidase N
BTL48_05600	COG0312	modulator of DNA gyrase
BTL48_05605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTL48_05620	COG2801	Transposase and inactivated derivatives
BTL48_05630	COG0277	FAD linked oxidase domain protein
BTL48_05635	COG0277	FAD linked oxidase domain protein
BTL48_05640	COG0247	lactate metabolic process
BTL48_05645	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BTL48_05650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BTL48_05675	COG0583	DNA-binding transcription factor activity
BTL48_05680	COG0482	sulfurtransferase activity
BTL48_05685	COG0730	response to heat
BTL48_05690	COG0625	glutathione transferase activity
BTL48_05695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTL48_05700	COG3909	cytochrome
BTL48_05715	COG2801	Transposase and inactivated derivatives
BTL48_05740	COG3706	GGDEF domain
BTL48_05750	COG2801	Transposase and inactivated derivatives
BTL48_05760	COG2826	transposase and inactivated derivatives, IS30 family
BTL48_05780	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BTL48_05800	COG0069	glutamate synthase activity
BTL48_05805	COG2391	methyltransferase activity
BTL48_05810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTL48_05815	COG0679	Auxin Efflux Carrier
BTL48_05820	COG2153	protein acetylation
BTL48_05840	COG0557	exoribonuclease II activity
BTL48_05845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTL48_05850	COG2873	o-acetylhomoserine
BTL48_05855	COG0776	regulation of translation
BTL48_05880	COG0745	RESPONSE REGULATOR receiver
BTL48_05885	COG0642	Histidine kinase
BTL48_05890	COG3158	transport of potassium into the cell
BTL48_05910	COG2801	Transposase and inactivated derivatives
BTL48_05915	COG0137	argininosuccinate synthase activity
BTL48_05920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BTL48_05925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTL48_05935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL48_05950	COG2186	Transcriptional regulator
BTL48_05980	COG3836	Belongs to the HpcH HpaI aldolase family
BTL48_05985	COG0268	Binds directly to 16S ribosomal RNA
BTL48_06040	COG0728	peptidoglycan biosynthetic process
BTL48_06050	COG0563	adenylate kinase activity
BTL48_06055	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BTL48_06060	COG2835	tetraacyldisaccharide 4'-kinase activity
BTL48_06065	COG1663	tetraacyldisaccharide 4'-kinase activity
BTL48_06070	COG0848	biopolymer transport protein
BTL48_06075	COG0811	peptide transport
BTL48_06080	COG1570	exodeoxyribonuclease VII activity
BTL48_06085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTL48_06090	COG2801	Transposase and inactivated derivatives
BTL48_06100	COG0038	chloride channel
BTL48_06105	COG0183	Belongs to the thiolase family
BTL48_06115	COG1278	Cold shock
BTL48_06120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BTL48_06135	COG4953	penicillin-binding protein 1C
BTL48_06150	COG3008	intermembrane lipid transfer
BTL48_06160	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BTL48_06160	COG0506	proline dehydrogenase activity
BTL48_06160	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BTL48_06170	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL48_06195	COG0004	ammonium transporteR
BTL48_06200	COG0347	Belongs to the P(II) protein family
BTL48_06235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTL48_06240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BTL48_06245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTL48_06250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL48_06250	COG0072	phenylalanine-tRNA ligase activity
BTL48_06255	COG0776	regulation of translation
BTL48_06285	COG1802	Transcriptional regulator
BTL48_06290	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_06300	COG0473	3-isopropylmalate dehydrogenase activity
BTL48_06315	COG1278	Cold shock
BTL48_06325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTL48_06345	COG1522	sequence-specific DNA binding
BTL48_06395	COG5265	(ABC) transporter
BTL48_06400	COG0656	L-ascorbic acid biosynthetic process
BTL48_06410	COG2801	Transposase and inactivated derivatives
BTL48_06420	COG0667	Aldo Keto reductase
BTL48_06435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTL48_06475	COG1610	YqeY-like protein
BTL48_06480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL48_06480	COG1017	nitric oxide dioxygenase activity
BTL48_06490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL48_06495	COG3246	L-lysine catabolic process to acetate
BTL48_06500	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL48_06510	COG0318	PFAM AMP-dependent synthetase and ligase
BTL48_06525	COG0183	Belongs to the thiolase family
BTL48_06530	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL48_06530	COG1024	Enoyl-CoA hydratase
BTL48_06540	COG1024	Enoyl-CoA hydratase
BTL48_06540	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL48_06550	COG1960	acyl-CoA dehydrogenase activity
BTL48_06560	COG1045	serine acetyltransferase
BTL48_06570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BTL48_06575	COG0483	inositol monophosphate 1-phosphatase activity
BTL48_06580	COG1012	belongs to the aldehyde dehydrogenase family
BTL48_06585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTL48_06600	COG0210	DNA helicase
BTL48_06605	COG0598	Magnesium transport protein CorA
BTL48_06615	COG0747	negative chemotaxis
BTL48_06620	COG0601	transmembrane transport
BTL48_06625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL48_06630	COG4172	Belongs to the ABC transporter superfamily
BTL48_06650	COG1346	cytolysis
BTL48_06660	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_06685	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BTL48_06695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL48_06700	COG1845	cytochrome c oxidase, subunit III
BTL48_06705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTL48_06755	COG1666	GTP binding
BTL48_06780	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_06785	COG5006	permease, DMT superfamily
BTL48_06810	COG2264	protein methyltransferase activity
BTL48_06820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTL48_06845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTL48_06850	COG0746	molybdenum cofactor guanylyltransferase activity
BTL48_06855	COG0303	'Molybdopterin
BTL48_06860	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTL48_06865	COG0314	molybdopterin synthase activity
BTL48_06875	COG0315	cyclic pyranopterin monophosphate synthase activity
BTL48_06880	COG0412	Dienelactone hydrolase
BTL48_06890	COG0678	peroxiredoxin activity
BTL48_06905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTL48_06915	COG0542	response to heat
BTL48_06930	COG1477	protein flavinylation
BTL48_06955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BTL48_06960	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BTL48_06960	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BTL48_06965	COG1562	ergosterol biosynthetic process
BTL48_06970	COG1562	ergosterol biosynthetic process
BTL48_06975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTL48_07015	COG0254	rRNA binding
BTL48_07020	COG3483	tryptophan 2,3-dioxygenase activity
BTL48_07025	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BTL48_07030	COG2003	Belongs to the UPF0758 family
BTL48_07045	COG0625	glutathione transferase activity
BTL48_07065	COG0523	cobalamin synthesis protein
BTL48_07075	COG0583	DNA-binding transcription factor activity
BTL48_07085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BTL48_07090	COG1187	pseudouridine synthase activity
BTL48_07095	COG0779	Required for maturation of 30S ribosomal subunits
BTL48_07100	COG2251	uridine kinase activity
BTL48_07100	COG0195	Participates in both transcription termination and antitermination
BTL48_07105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BTL48_07110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTL48_07115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BTL48_07135	COG1802	Transcriptional regulator
BTL48_07145	COG1024	Enoyl-CoA hydratase
BTL48_07150	COG0318	PFAM AMP-dependent synthetase and ligase
BTL48_07160	COG2032	superoxide dismutase activity
BTL48_07175	COG4120	Belongs to the binding-protein-dependent transport system permease family
BTL48_07180	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BTL48_07185	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTL48_07190	COG4149	molybdate abc transporter
BTL48_07220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL48_07225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL48_07230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTL48_07235	COG1538	Outer membrane efflux protein
BTL48_07240	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BTL48_07245	COG0736	holo-[acyl-carrier-protein] synthase activity
BTL48_07250	COG1472	Belongs to the glycosyl hydrolase 3 family
BTL48_07255	COG0322	excinuclease ABC activity
BTL48_07260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTL48_07270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTL48_07270	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTL48_07275	COG2224	Isocitrate lyase
BTL48_07280	COG1846	Transcriptional regulator
BTL48_07285	COG1764	response to oxidative stress
BTL48_07290	COG1131	(ABC) transporter
BTL48_07300	COG0628	permease
BTL48_07315	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BTL48_07325	COG2814	Major facilitator Superfamily
BTL48_07345	COG3015	lipoprotein NlpE involved in copper resistance
BTL48_07355	COG3530	Putative quorum-sensing-regulated virulence factor
BTL48_07370	COG0494	nUDIX hydrolase
BTL48_07375	COG0633	Ferredoxin
BTL48_07380	COG0697	spore germination
BTL48_07385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BTL48_07410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTL48_07415	COG1702	phosphate starvation-inducible protein PhoH
BTL48_07420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BTL48_07425	COG4535	Mg2 and Co2 transporter CorC
BTL48_07430	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BTL48_07435	COG0667	Aldo Keto reductase
BTL48_07455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL48_07460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL48_07465	COG1862	Preprotein translocase
BTL48_07470	COG0343	queuine tRNA-ribosyltransferase activity
BTL48_07475	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BTL48_07480	COG2027	D-alanyl-D-alanine carboxypeptidase
BTL48_07485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BTL48_07490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTL48_07490	COG1648	precorrin-2 dehydrogenase activity
BTL48_07500	COG4575	ribosome binding
BTL48_07520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BTL48_07525	COG0741	lytic transglycosylase activity
BTL48_07530	COG0436	Aminotransferase
BTL48_07540	COG0280	phosphate acetyltransferase
BTL48_07540	COG0281	malic enzyme
BTL48_07555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTL48_07560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTL48_07565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTL48_07570	COG0126	phosphoglycerate kinase activity
BTL48_07585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BTL48_07600	COG0625	glutathione transferase activity
BTL48_07620	COG0789	Transcriptional regulator
BTL48_07635	COG0306	phosphate transporter
BTL48_07640	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTL48_07650	COG0739	heme binding
BTL48_07660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTL48_07705	COG0456	acetyltransferase
BTL48_07710	COG1301	dicarboxylic acid transport
BTL48_07720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BTL48_07725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTL48_07730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTL48_07735	COG0009	L-threonylcarbamoyladenylate synthase
BTL48_07745	COG4771	TonB-dependent receptor
BTL48_07775	COG1960	acyl-CoA dehydrogenase activity
BTL48_07780	COG0028	Belongs to the TPP enzyme family
BTL48_07785	COG0583	DNA-binding transcription factor activity
BTL48_07790	COG4974	Belongs to the 'phage' integrase family
BTL48_07795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTL48_07800	COG1686	Belongs to the peptidase S11 family
BTL48_07830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTL48_07835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BTL48_07840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BTL48_07860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL48_07865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTL48_07870	COG0505	Belongs to the CarA family
BTL48_07875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BTL48_07885	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_07890	COG0406	alpha-ribazole phosphatase activity
BTL48_07920	COG2233	PERMEase
BTL48_07925	COG3620	sequence-specific DNA binding
BTL48_07935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTL48_07945	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BTL48_07950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTL48_07960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTL48_07975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BTL48_07990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTL48_08010	COG2801	Transposase and inactivated derivatives
BTL48_08040	COG2801	Transposase and inactivated derivatives
BTL48_08060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL48_08095	COG0540	Belongs to the ATCase OTCase family
BTL48_08100	COG2974	May be involved in recombination
BTL48_08115	COG0642	Histidine kinase
BTL48_08125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BTL48_08130	COG2137	regulation of response to DNA damage stimulus
BTL48_08135	COG0583	DNA-binding transcription factor activity
BTL48_08140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BTL48_08155	COG0045	succinate-CoA ligase (ADP-forming) activity
BTL48_08160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTL48_08165	COG0861	Integral membrane protein TerC family
BTL48_08170	COG0861	Integral membrane protein TerC family
BTL48_08175	COG0181	hydroxymethylbilane synthase activity
BTL48_08195	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BTL48_08215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTL48_08255	COG1450	Type ii and iii secretion system protein
BTL48_08270	COG2801	Transposase and inactivated derivatives
BTL48_08300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTL48_08310	COG1295	ribonuclease BN
BTL48_08320	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BTL48_08340	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BTL48_08345	COG0501	Belongs to the peptidase M48B family
BTL48_08350	COG2197	response regulator
BTL48_08375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTL48_08380	COG0066	3-isopropylmalate dehydratase activity
BTL48_08390	COG0473	3-isopropylmalate dehydrogenase activity
BTL48_08395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTL48_08405	COG0101	tRNA pseudouridine synthase activity
BTL48_08410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL48_08415	COG0135	phosphoribosylanthranilate isomerase activity
BTL48_08430	COG2801	Transposase and inactivated derivatives
BTL48_08435	COG2963	transposase activity
BTL48_08470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTL48_08475	COG2197	response regulator
BTL48_08480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTL48_08485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BTL48_08490	COG0189	ligase activity
BTL48_08500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTL48_08505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTL48_08515	COG1764	response to oxidative stress
BTL48_08530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL48_08535	COG0765	amino acid transport
BTL48_08540	COG0765	amino acid transport
BTL48_08545	COG1126	abc transporter atp-binding protein
BTL48_08550	COG0756	dUTP diphosphatase activity
BTL48_08580	COG1522	sequence-specific DNA binding
BTL48_08600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTL48_08605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BTL48_08610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BTL48_08615	COG0196	riboflavin kinase activity
BTL48_08625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL48_08625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTL48_08640	COG2801	Transposase and inactivated derivatives
BTL48_08650	COG0210	DNA helicase
BTL48_08655	COG4771	TonB-dependent receptor
BTL48_08660	COG0488	(ABC) transporter
BTL48_08665	COG2890	protein-(glutamine-N5) methyltransferase activity
BTL48_08670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTL48_08675	COG2171	N-acyltransferase activity
BTL48_08730	COG2801	Transposase and inactivated derivatives
BTL48_08750	COG2801	Transposase and inactivated derivatives
BTL48_08770	COG2814	Major facilitator Superfamily
BTL48_08795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTL48_08800	COG2900	Belongs to the SlyX family
BTL48_08815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL48_08835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL48_08860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTL48_08865	COG0583	DNA-binding transcription factor activity
BTL48_08870	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_08880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL48_08885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTL48_08895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTL48_08900	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTL48_08905	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BTL48_08915	COG4566	intracellular signal transduction
BTL48_08920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BTL48_08940	COG1999	signal sequence binding
BTL48_08950	COG1538	Outer membrane efflux protein
BTL48_08960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL48_08965	COG0583	DNA-binding transcription factor activity
BTL48_08970	COG1187	pseudouridine synthase activity
BTL48_08975	COG3161	chorismate lyase activity
BTL48_08985	COG4681	YaeQ
BTL48_08990	COG1280	lysine exporter protein (LysE YggA)
BTL48_09025	COG1129	ABC transporter
BTL48_09035	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL48_09040	COG0583	DNA-binding transcription factor activity
BTL48_09050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTL48_09070	COG1185	polyribonucleotide nucleotidyltransferase activity
BTL48_09075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BTL48_09090	COG1183	phosphatidylcholine synthase activity
BTL48_09095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BTL48_09100	COG0440	acetolactate synthase activity
BTL48_09105	COG0028	Belongs to the TPP enzyme family
BTL48_09130	COG3022	response to hydroperoxide
BTL48_09140	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_09185	COG2814	Major facilitator Superfamily
BTL48_09225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL48_09260	COG2733	membrane
BTL48_09280	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BTL48_09300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL48_09305	COG0842	Transport permease protein
BTL48_09305	COG1129	ABC transporter
BTL48_09310	COG0842	Transport permease protein
BTL48_09320	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_09330	COG2259	Doxx family
BTL48_09360	COG0415	Belongs to the DNA photolyase family
BTL48_09380	COG0386	Belongs to the glutathione peroxidase family
BTL48_09395	COG0095	Lipoate-protein ligase
BTL48_09405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTL48_09415	COG0010	Belongs to the arginase family
BTL48_09425	COG0765	amino acid transport
BTL48_09430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL48_09445	COG0084	hydrolase, TatD family'
BTL48_09455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTL48_09460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTL48_09475	COG0583	DNA-binding transcription factor activity
BTL48_09500	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTL48_09520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BTL48_09540	COG3447	MASE1 domain protein
BTL48_09540	COG5002	protein histidine kinase activity
BTL48_09540	COG5001	Diguanylate cyclase
BTL48_09560	COG0519	Catalyzes the synthesis of GMP from XMP
BTL48_09560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTL48_09570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BTL48_09580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTL48_09585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BTL48_09590	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL48_09600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTL48_09605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL48_09615	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL48_09620	COG0750	zinc metalloprotease
BTL48_09625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BTL48_09635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BTL48_09640	COG0233	cytoplasmic translational termination
BTL48_09645	COG0528	UMP kinase activity
BTL48_09650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTL48_09655	COG0052	Belongs to the universal ribosomal protein uS2 family
BTL48_09660	COG0024	Methionine aminopeptidase
BTL48_09665	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BTL48_09685	COG1286	toxin biosynthetic process
BTL48_09695	COG0285	dihydrofolate synthase activity
BTL48_09705	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_09710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_09750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTL48_09760	COG1677	Flagellar hook-basal body complex protein FliE
BTL48_09770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTL48_09775	COG1317	bacterial-type flagellum organization
BTL48_09795	COG1580	Controls the rotational direction of flagella during chemotaxis
BTL48_09805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTL48_09820	COG1987	bacterial-type flagellum assembly
BTL48_09830	COG0840	transmembrane signaling receptor activity
BTL48_09835	COG0840	transmembrane signaling receptor activity
BTL48_09860	COG1191	sigma factor activity
BTL48_09900	COG2199	diguanylate cyclase activity
BTL48_09900	COG2203	Gaf domain
BTL48_09910	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTL48_09940	COG0765	amino acid transport
BTL48_09970	COG0410	ABC transporter
BTL48_09975	COG0411	ABC transporter
BTL48_10005	COG1253	flavin adenine dinucleotide binding
BTL48_10010	COG4251	negative regulation of phosphorylation
BTL48_10010	COG3706	GGDEF domain
BTL48_10010	COG5001	Diguanylate cyclase
BTL48_10010	COG2203	Gaf domain
BTL48_10015	COG2197	response regulator
BTL48_10020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL48_10020	COG2205	protein histidine kinase activity
BTL48_10040	COG2801	Transposase and inactivated derivatives
BTL48_10045	COG0076	glutamate decarboxylase activity
BTL48_10050	COG2985	domain, Protein
BTL48_10055	COG3189	MarR family transcriptional regulator
BTL48_10065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL48_10085	COG0028	Belongs to the TPP enzyme family
BTL48_10095	COG1012	belongs to the aldehyde dehydrogenase family
BTL48_10105	COG0688	phosphatidylethanolamine metabolic process
BTL48_10110	COG1304	FMN binding
BTL48_10115	COG1464	Belongs to the NlpA lipoprotein family
BTL48_10120	COG2801	Transposase and inactivated derivatives
BTL48_10135	COG0697	spore germination
BTL48_10140	COG2133	pyrroloquinoline quinone binding
BTL48_10145	COG0625	glutathione transferase activity
BTL48_10155	COG1794	racemase activity, acting on amino acids and derivatives
BTL48_10175	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL48_10185	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BTL48_10200	COG1175	transmembrane transport
BTL48_10205	COG0395	ABC-type sugar transport system, permease component
BTL48_10210	COG3842	ATPase activity
BTL48_10230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BTL48_10245	COG0438	transferase activity, transferring glycosyl groups
BTL48_10270	COG0463	Glycosyl transferase, family 2
BTL48_10285	COG0783	Belongs to the Dps family
BTL48_10290	COG0583	DNA-binding transcription factor activity
BTL48_10295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTL48_10320	COG1840	ABC-type Fe3 transport system, periplasmic component
BTL48_10330	COG3842	ATPase activity
BTL48_10335	COG1741	Belongs to the pirin family
BTL48_10345	COG0583	DNA-binding transcription factor activity
BTL48_10355	COG3852	Histidine kinase
BTL48_10365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTL48_10370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BTL48_10380	COG0840	transmembrane signaling receptor activity
BTL48_10390	COG0583	DNA-binding transcription factor activity
BTL48_10395	COG1960	acyl-CoA dehydrogenase activity
BTL48_10400	COG2079	MmgE PrpD family protein
BTL48_10410	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BTL48_10415	COG1561	YicC-like family, N-terminal region
BTL48_10425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTL48_10430	COG0791	NLP P60 protein
BTL48_10435	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_10440	COG0194	GDP metabolic process
BTL48_10445	COG1758	RNA polymerase activity
BTL48_10450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTL48_10455	COG1126	abc transporter atp-binding protein
BTL48_10460	COG0765	amino acid transport
BTL48_10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL48_10475	COG2831	hemolysin activation secretion protein
BTL48_10485	COG3188	usher protein
BTL48_10490	COG3121	Chaperone
BTL48_10515	COG3064	Membrane
BTL48_10515	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BTL48_10515	COG3210	domain, Protein
BTL48_10525	COG4181	ATPase activity
BTL48_10535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL48_10540	COG0584	glycerophosphoryl diester phosphodiesterase
BTL48_10545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BTL48_10555	COG0678	peroxiredoxin activity
BTL48_10555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTL48_10565	COG2217	Heavy metal translocating P-type atpase
BTL48_10570	COG0789	Transcriptional regulator
BTL48_10575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTL48_10585	COG2801	Transposase and inactivated derivatives
BTL48_10610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BTL48_10615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BTL48_10620	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTL48_10645	COG0583	DNA-binding transcription factor activity
BTL48_10650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BTL48_10655	COG2252	PERMEase
BTL48_10660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTL48_10665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL48_10700	COG0488	(ABC) transporter
BTL48_10705	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTL48_10710	COG0590	tRNA wobble adenosine to inosine editing
BTL48_10725	COG1320	monovalent cation:proton antiporter activity
BTL48_10730	COG2212	antiporter activity
BTL48_10735	COG1863	multisubunit Na H antiporter MnhE subunit
BTL48_10740	COG0651	ATP synthesis coupled electron transport
BTL48_10745	COG1006	Multisubunit Na H antiporter MnhC subunit
BTL48_10750	COG2111	Na H antiporter
BTL48_10750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTL48_10755	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_10775	COG0420	3'-5' exonuclease activity
BTL48_10805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTL48_10815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTL48_10825	COG2130	NADP-dependent
BTL48_10830	COG1309	transcriptional regulator
BTL48_10840	COG1131	(ABC) transporter
BTL48_10845	COG0842	Transport permease protein
BTL48_10855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTL48_10890	COG0602	queuosine metabolic process
BTL48_10895	COG0720	synthase
BTL48_10910	COG0840	transmembrane signaling receptor activity
BTL48_10925	COG0587	DNA-directed DNA polymerase activity
BTL48_10935	COG0390	transport system, permease component
BTL48_10940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTL48_10945	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BTL48_10995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTL48_11020	COG5507	3-demethylubiquinone-9 3-methyltransferase
BTL48_11055	COG1396	sequence-specific DNA binding
BTL48_11085	COG0583	DNA-binding transcription factor activity
BTL48_11090	COG2814	Major facilitator Superfamily
BTL48_11115	COG2807	transmembrane transport
BTL48_11120	COG2207	Transcriptional regulator
BTL48_11130	COG2814	Major facilitator Superfamily
BTL48_11145	COG1012	belongs to the aldehyde dehydrogenase family
BTL48_11180	COG0583	DNA-binding transcription factor activity
BTL48_11200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTL48_11225	COG0384	phenazine biosynthesis protein PhzF
BTL48_11230	COG1733	regulation of RNA biosynthetic process
BTL48_11265	COG3177	Filamentation induced by cAMP protein fic
BTL48_11275	COG0519	Catalyzes the synthesis of GMP from XMP
BTL48_11275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTL48_11290	COG1695	Transcriptional regulator
BTL48_11305	COG2072	flavoprotein involved in K transport
BTL48_11310	COG0601	transmembrane transport
BTL48_11335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL48_11345	COG4608	Belongs to the ABC transporter superfamily
BTL48_11350	COG0747	negative chemotaxis
BTL48_11390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTL48_11390	COG0047	phosphoribosylformylglycinamidine synthase activity
BTL48_11395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL48_11425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL48_11435	COG0613	PHP domain protein
BTL48_11495	COG1012	belongs to the aldehyde dehydrogenase family
BTL48_11505	COG0583	DNA-binding transcription factor activity
BTL48_11525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL48_11535	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_11540	COG2801	Transposase and inactivated derivatives
BTL48_11545	COG2963	transposase activity
BTL48_11550	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_11580	COG1595	DNA-templated transcription, initiation
BTL48_11585	COG3712	iron ion homeostasis
BTL48_11595	COG0084	hydrolase, TatD family'
BTL48_11600	COG1136	(ABC) transporter
BTL48_11615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTL48_11625	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_11630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BTL48_11640	COG1803	Methylglyoxal synthase
BTL48_11680	COG2963	transposase activity
BTL48_11690	COG2975	iron-sulfur cluster assembly
BTL48_11695	COG0633	Ferredoxin
BTL48_11700	COG0443	Heat shock 70 kDa protein
BTL48_11705	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BTL48_11710	COG0316	Belongs to the HesB IscA family
BTL48_11715	COG0822	iron-sulfur transferase activity
BTL48_11720	COG1104	cysteine desulfurase activity
BTL48_11730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTL48_11735	COG0556	nucleotide-excision repair
BTL48_11750	COG0583	DNA-binding transcription factor activity
BTL48_11770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL48_11805	COG2801	Transposase and inactivated derivatives
BTL48_11810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTL48_11820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTL48_11825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BTL48_11830	COG0740	serine-type endopeptidase activity
BTL48_11835	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTL48_11850	COG2801	Transposase and inactivated derivatives
BTL48_11890	COG2963	transposase activity
BTL48_11895	COG2801	Transposase and inactivated derivatives
BTL48_11900	COG1530	ribonuclease E activity
BTL48_11910	COG2801	Transposase and inactivated derivatives
BTL48_11930	COG1846	Transcriptional regulator
BTL48_11940	COG1566	PFAM secretion protein HlyD family protein
BTL48_11945	COG2814	Major facilitator Superfamily
BTL48_11950	COG0473	3-isopropylmalate dehydrogenase activity
BTL48_11970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL48_11975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL48_11980	COG0433	COG0433 Predicted ATPase
BTL48_11985	COG0217	transcriptional regulatory protein
BTL48_11990	COG0151	Belongs to the GarS family
BTL48_11995	COG0408	coproporphyrinogen oxidase activity
BTL48_12000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BTL48_12005	COG0799	negative regulation of ribosome biogenesis
BTL48_12010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BTL48_12015	COG0424	maF-like protein
BTL48_12025	COG4191	Histidine kinase
BTL48_12030	COG2204	response regulator
BTL48_12055	COG0500	methyltransferase
BTL48_12070	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTL48_12075	COG1121	(ABC) transporter
BTL48_12080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTL48_12085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTL48_12120	COG4993	Dehydrogenase
BTL48_12130	COG4772	TonB-dependent receptor
BTL48_12135	COG2814	Major facilitator Superfamily
BTL48_12155	COG0037	tRNA processing
BTL48_12160	COG0825	malonyl-CoA metabolic process
BTL48_12170	COG0215	cysteine-tRNA ligase activity
BTL48_12180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTL48_12185	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL48_12190	COG1968	undecaprenyl-diphosphatase activity
BTL48_12195	COG1253	flavin adenine dinucleotide binding
BTL48_12220	COG0668	transmembrane transport
BTL48_12245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTL48_12255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BTL48_12270	COG1802	Transcriptional regulator
BTL48_12290	COG3360	Dodecin
BTL48_12310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BTL48_12315	COG2850	peptidyl-arginine hydroxylation
BTL48_12325	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BTL48_12330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL48_12335	COG1994	Peptidase M50
BTL48_12340	COG0009	L-threonylcarbamoyladenylate synthase
BTL48_12345	COG2321	neutral zinc metallopeptidase
BTL48_12365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL48_12375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL48_12385	COG2271	Major facilitator Superfamily
BTL48_12415	COG2801	Transposase and inactivated derivatives
BTL48_12420	COG2963	transposase activity
BTL48_12465	COG2199	diguanylate cyclase activity
BTL48_12465	COG2200	EAL domain
BTL48_12465	COG2202	Pas domain
BTL48_12470	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BTL48_12490	COG1960	acyl-CoA dehydrogenase activity
BTL48_12495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_12500	COG2186	Transcriptional regulator
BTL48_12525	COG1595	DNA-templated transcription, initiation
BTL48_12545	COG2801	Transposase and inactivated derivatives
BTL48_12575	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTL48_12595	COG4604	ABC transporter, ATP-binding protein
BTL48_12600	COG4605	iron ion homeostasis
BTL48_12605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTL48_12610	COG4607	ABC-type enterochelin transport system periplasmic component
BTL48_12615	COG0438	transferase activity, transferring glycosyl groups
BTL48_12625	COG0149	triose-phosphate isomerase activity
BTL48_12655	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BTL48_12655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTL48_12660	COG0668	transmembrane transport
BTL48_12665	COG0165	Argininosuccinate lyase
BTL48_12675	COG0789	Transcriptional regulator
BTL48_12685	COG0501	Belongs to the peptidase M48B family
BTL48_12690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL48_12715	COG1024	Enoyl-CoA hydratase
BTL48_12720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_12740	COG3468	outer membrane autotransporter barrel domain protein
BTL48_12780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BTL48_12785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTL48_12790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTL48_12795	COG1674	ftsk spoiiie
BTL48_12800	COG0492	ferredoxin-NADP+ reductase activity
BTL48_12805	COG1193	negative regulation of DNA recombination
BTL48_12820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTL48_12835	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BTL48_12840	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BTL48_12845	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BTL48_12855	COG0745	RESPONSE REGULATOR receiver
BTL48_12890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTL48_12910	COG0612	Peptidase, M16
BTL48_12915	COG0484	heat shock protein binding
BTL48_12920	COG0443	Heat shock 70 kDa protein
BTL48_12930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BTL48_12940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BTL48_12945	COG1420	regulation of RNA biosynthetic process
BTL48_12950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BTL48_12955	COG0497	DNA recombination
BTL48_12985	COG0735	belongs to the Fur family
BTL48_12990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL48_12995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BTL48_13010	COG2801	Transposase and inactivated derivatives
BTL48_13020	COG2801	Transposase and inactivated derivatives
BTL48_13040	COG2828	Protein conserved in bacteria
BTL48_13045	COG1280	lysine exporter protein (LysE YggA)
BTL48_13050	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_13065	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_13070	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTL48_13075	COG1802	Transcriptional regulator
BTL48_13080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTL48_13085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BTL48_13090	COG1335	isochorismatase
BTL48_13095	COG0523	cobalamin synthesis protein
BTL48_13125	COG0583	DNA-binding transcription factor activity
BTL48_13135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BTL48_13140	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BTL48_13145	COG0167	dihydroorotate dehydrogenase activity
BTL48_13160	COG2801	Transposase and inactivated derivatives
BTL48_13185	COG1414	Transcriptional regulator
BTL48_13205	COG0513	Belongs to the DEAD box helicase family
BTL48_13230	COG0429	hydrolase of the alpha beta-hydrolase fold
BTL48_13235	COG4783	chaperone-mediated protein folding
BTL48_13260	COG2801	Transposase and inactivated derivatives
BTL48_13275	COG0006	proline dipeptidase activity
BTL48_13285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL48_13310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BTL48_13315	COG0632	four-way junction helicase activity
BTL48_13330	COG2255	four-way junction helicase activity
BTL48_13335	COG0514	ATP-dependent DNA helicase (RecQ)
BTL48_13345	COG0745	RESPONSE REGULATOR receiver
BTL48_13355	COG1294	oxidase, subunit
BTL48_13365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL48_13370	COG0850	regulation of cytokinetic process
BTL48_13375	COG2894	cell division
BTL48_13380	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BTL48_13400	COG0488	(ABC) transporter
BTL48_13415	COG4608	Belongs to the ABC transporter superfamily
BTL48_13420	COG0444	Belongs to the ABC transporter superfamily
BTL48_13425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL48_13440	COG1215	transferase activity, transferring glycosyl groups
BTL48_13445	COG0583	DNA-binding transcription factor activity
BTL48_13450	COG1368	sulfuric ester hydrolase activity
BTL48_13465	COG1280	lysine exporter protein (LysE YggA)
BTL48_13475	COG1064	alcohol dehydrogenase
BTL48_13485	COG4566	intracellular signal transduction
BTL48_13495	COG1802	Transcriptional regulator
BTL48_13515	COG1053	succinate dehydrogenase
BTL48_13520	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_13525	COG0513	Belongs to the DEAD box helicase family
BTL48_13530	COG0668	transmembrane transport
BTL48_13545	COG1595	DNA-templated transcription, initiation
BTL48_13585	COG0583	DNA-binding transcription factor activity
BTL48_13590	COG0531	amino acid
BTL48_13595	COG1982	Orn Lys Arg decarboxylase major
BTL48_13615	COG2801	Transposase and inactivated derivatives
BTL48_13620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BTL48_13625	COG0459	protein refolding
BTL48_13635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTL48_13640	COG1252	NADH dehydrogenase
BTL48_13645	COG0284	orotidine-5'-phosphate decarboxylase activity
BTL48_13655	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTL48_13665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL48_13670	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BTL48_13700	COG1595	DNA-templated transcription, initiation
BTL48_13710	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BTL48_13715	COG3639	organic phosphonate transmembrane transporter activity
BTL48_13720	COG3639	organic phosphonate transmembrane transporter activity
BTL48_13735	COG0742	ribosomal rna small subunit methyltransferase
BTL48_13740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BTL48_13745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTL48_13750	COG3135	benzoate transporter
BTL48_13770	COG4774	siderophore transport
BTL48_13795	COG1024	Enoyl-CoA hydratase
BTL48_13800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL48_13805	COG1960	acyl-CoA dehydrogenase activity
BTL48_13815	COG0318	PFAM AMP-dependent synthetase and ligase
BTL48_13820	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_13830	COG0583	DNA-binding transcription factor activity
BTL48_13855	COG0277	FAD linked oxidase domain protein
BTL48_13875	COG1802	Transcriptional regulator
BTL48_13885	COG2271	Major facilitator Superfamily
BTL48_13895	COG0583	DNA-binding transcription factor activity
BTL48_13920	COG0012	GTP binding
BTL48_13930	COG0193	aminoacyl-tRNA hydrolase activity
BTL48_13935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BTL48_13940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BTL48_13950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BTL48_13955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BTL48_13965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BTL48_13995	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BTL48_14005	COG1368	sulfuric ester hydrolase activity
BTL48_14010	COG2186	Transcriptional regulator
BTL48_14020	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_14035	COG0277	FAD linked oxidase domain protein
BTL48_14050	COG0166	Belongs to the GPI family
BTL48_14055	COG0438	transferase activity, transferring glycosyl groups
BTL48_14060	COG0438	transferase activity, transferring glycosyl groups
BTL48_14075	COG0438	transferase activity, transferring glycosyl groups
BTL48_14090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BTL48_14095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTL48_14105	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BTL48_14115	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BTL48_14125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL48_14145	COG0747	negative chemotaxis
BTL48_14155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL48_14160	COG4172	Belongs to the ABC transporter superfamily
BTL48_14180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTL48_14180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTL48_14185	COG0509	glycine decarboxylation via glycine cleavage system
BTL48_14190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BTL48_14195	COG2081	HI0933 family
BTL48_14200	COG1982	Orn Lys Arg decarboxylase major
BTL48_14210	COG0456	acetyltransferase
BTL48_14215	COG0717	Belongs to the dCTP deaminase family
BTL48_14230	COG0489	protein tyrosine kinase activity
BTL48_14240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL48_14240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL48_14265	COG3539	Fimbrial protein
BTL48_14280	COG0745	RESPONSE REGULATOR receiver
BTL48_14300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTL48_14305	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BTL48_14320	COG2084	Dehydrogenase
BTL48_14325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL48_14350	COG3842	ATPase activity
BTL48_14355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL48_14360	COG1960	acyl-CoA dehydrogenase activity
BTL48_14370	COG0583	DNA-binding transcription factor activity
BTL48_14380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_14385	COG1024	Enoyl-CoA hydratase
BTL48_14400	COG0583	DNA-binding transcription factor activity
BTL48_14405	COG1408	metallophosphoesterase
BTL48_14410	COG0625	glutathione transferase activity
BTL48_14445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL48_14445	COG0426	domain, Protein
BTL48_14450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTL48_14455	COG0583	DNA-binding transcription factor activity
BTL48_14465	COG1024	Enoyl-CoA hydratase
BTL48_14470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTL48_14470	COG0045	succinate-CoA ligase (ADP-forming) activity
BTL48_14470	COG1042	CoA-binding domain protein
BTL48_14475	COG1960	acyl-CoA dehydrogenase activity
BTL48_14485	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_14500	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_14505	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_14515	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_14555	COG0583	DNA-binding transcription factor activity
BTL48_14560	COG1960	acyl-CoA dehydrogenase activity
BTL48_14565	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_14570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_14575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BTL48_14595	COG2801	Transposase and inactivated derivatives
BTL48_14600	COG0560	Phosphoserine phosphatase
BTL48_14605	COG0583	DNA-binding transcription factor activity
BTL48_14615	COG3842	ATPase activity
BTL48_14630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTL48_14650	COG0625	glutathione transferase activity
BTL48_14655	COG0410	ABC transporter
BTL48_14660	COG0411	ABC transporter
BTL48_14680	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL48_14690	COG4336	lyase activity
BTL48_14700	COG0326	Molecular chaperone. Has ATPase activity
BTL48_14705	COG2233	PERMEase
BTL48_14725	COG2801	Transposase and inactivated derivatives
BTL48_14745	COG2818	Glycosylase
BTL48_14775	COG0402	S-adenosylhomocysteine deaminase activity
BTL48_14785	COG0156	8-amino-7-oxononanoate synthase activity
BTL48_14790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BTL48_14815	COG2801	Transposase and inactivated derivatives
BTL48_14845	COG1464	Belongs to the NlpA lipoprotein family
BTL48_14850	COG2011	ABC-type metal ion transport system permease component
BTL48_14855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTL48_14860	COG1501	Belongs to the glycosyl hydrolase 31 family
BTL48_14865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL48_14865	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BTL48_14870	COG0483	inositol monophosphate 1-phosphatase activity
BTL48_14875	COG0318	PFAM AMP-dependent synthetase and ligase
BTL48_14880	COG1473	amidohydrolase
BTL48_14885	COG0583	DNA-binding transcription factor activity
BTL48_14890	COG2855	membrane
BTL48_14895	COG1607	acyl-coa hydrolase
BTL48_14900	COG2239	Acts as a magnesium transporter
BTL48_14915	COG1522	sequence-specific DNA binding
BTL48_14955	COG0330	HflC and HflK could
BTL48_14960	COG0330	HflC and HflK could
BTL48_14965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTL48_14970	COG1923	regulation of RNA biosynthetic process
BTL48_14980	COG1160	GTP binding
BTL48_14985	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL48_14990	COG2976	Protein conserved in bacteria
BTL48_14995	COG0124	histidyl-tRNA synthetase
BTL48_15000	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BTL48_15010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTL48_15015	COG0105	UTP biosynthetic process
BTL48_15020	COG0525	valine-tRNA ligase activity
BTL48_15030	COG0336	Belongs to the RNA methyltransferase TrmD family
BTL48_15035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BTL48_15040	COG0228	four-way junction DNA binding
BTL48_15045	COG0425	Belongs to the sulfur carrier protein TusA family
BTL48_15050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTL48_15100	COG2801	Transposase and inactivated derivatives
BTL48_15115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL48_15120	COG0543	2 iron, 2 sulfur cluster binding
BTL48_15120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL48_15125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BTL48_15130	COG2076	Multidrug Resistance protein
BTL48_15135	COG0633	Ferredoxin
BTL48_15135	COG3217	Mosc domain protein beta barrel domain protein
BTL48_15140	COG5285	phytanoyl-CoA dioxygenase
BTL48_15145	COG0662	Cupin 2, conserved barrel domain protein
BTL48_15150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTL48_15155	COG0456	acetyltransferase
BTL48_15175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL48_15195	COG0187	DNA topoisomerase II activity
BTL48_15205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTL48_15215	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BTL48_15220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTL48_15225	COG1760	l-serine dehydratase
BTL48_15230	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTL48_15235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTL48_15240	COG0412	Dienelactone hydrolase
BTL48_15245	COG0428	transporter
BTL48_15255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BTL48_15260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL48_15265	COG1845	cytochrome c oxidase, subunit III
BTL48_15270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTL48_15280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTL48_15280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTL48_15305	COG1942	4-Oxalocrotonate Tautomerase
BTL48_15315	COG4176	ABC-type proline glycine betaine transport system permease component
BTL48_15330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTL48_15335	COG2814	Major facilitator Superfamily
BTL48_15340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BTL48_15345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTL48_15370	COG1846	Transcriptional regulator
BTL48_15375	COG2814	Major facilitator Superfamily
BTL48_15380	COG0495	leucyl-tRNA aminoacylation
BTL48_15395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BTL48_15415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL48_15420	COG2274	protein secretion by the type I secretion system
BTL48_15435	COG2801	Transposase and inactivated derivatives
BTL48_15465	COG0427	acetyl-CoA hydrolase
BTL48_15475	COG1511	domain protein
BTL48_15475	COG3264	Mechanosensitive ion channel
BTL48_15480	COG0730	response to heat
BTL48_15495	COG2176	DNA-directed DNA polymerase activity
BTL48_15515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTL48_15520	COG3384	dioxygenase
BTL48_15535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTL48_15560	COG2801	Transposase and inactivated derivatives
BTL48_15605	COG4964	Belongs to the GSP D family
BTL48_15650	COG1846	Transcriptional regulator
BTL48_15685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BTL48_15695	COG2070	2-Nitropropane dioxygenase
BTL48_15700	COG2070	2-Nitropropane dioxygenase
BTL48_15710	COG2610	gluconate transmembrane transporter activity
BTL48_15725	COG1408	metallophosphoesterase
BTL48_15735	COG5001	Diguanylate cyclase
BTL48_15735	COG3300	MHYT domain
BTL48_15740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTL48_15775	COG2159	amidohydrolase
BTL48_15785	COG0583	DNA-binding transcription factor activity
BTL48_15800	COG1024	Enoyl-CoA hydratase
BTL48_15805	COG2186	Transcriptional regulator
BTL48_15810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_15820	COG0833	amino acid
BTL48_15825	COG2894	cell division
BTL48_15830	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BTL48_15850	COG5265	(ABC) transporter
BTL48_15890	COG1971	Probably functions as a manganese efflux pump
BTL48_15895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL48_15905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL48_15910	COG2814	Major facilitator Superfamily
BTL48_15935	COG4608	Belongs to the ABC transporter superfamily
BTL48_15955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL48_15965	COG3383	formate dehydrogenase (NAD+) activity
BTL48_15980	COG0747	negative chemotaxis
BTL48_15990	COG0625	glutathione transferase activity
BTL48_16020	COG1595	DNA-templated transcription, initiation
BTL48_16030	COG4774	siderophore transport
BTL48_16045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTL48_16060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BTL48_16065	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BTL48_16090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL48_16095	COG1024	Enoyl-CoA hydratase
BTL48_16130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL48_16135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL48_16140	COG1116	anion transmembrane transporter activity
BTL48_16150	COG3585	molybdate ion transport
BTL48_16205	COG0583	DNA-binding transcription factor activity
BTL48_16210	COG4948	Mandelate Racemase Muconate Lactonizing
BTL48_16215	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_16245	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_16275	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL48_16280	COG4177	L-phenylalanine transmembrane transporter activity
BTL48_16305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTL48_16320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTL48_16325	COG1538	Outer membrane efflux protein
BTL48_16330	COG0577	efflux transmembrane transporter activity
BTL48_16330	COG1136	(ABC) transporter
BTL48_16335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL48_16350	COG0259	pyridoxamine-phosphate oxidase activity
BTL48_16355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL48_16360	COG0579	oxidoreductase
BTL48_16370	COG0405	Gamma-glutamyltransferase
BTL48_16380	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_16390	COG0114	fumarate hydratase activity
BTL48_16395	COG0802	atpase or kinase
BTL48_16400	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTL48_16405	COG0586	Pfam SNARE associated Golgi protein
BTL48_16410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BTL48_16415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BTL48_16420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BTL48_16435	COG0617	tRNA 3'-terminal CCA addition
BTL48_16455	COG2801	Transposase and inactivated derivatives
BTL48_16475	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BTL48_16485	COG1024	Enoyl-CoA hydratase
BTL48_16495	COG2188	Transcriptional regulator
BTL48_16515	COG0752	glycyl-tRNA synthetase alpha subunit
BTL48_16520	COG0751	glycine-tRNA ligase activity
BTL48_16525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTL48_16530	COG0204	Acyl-transferase
BTL48_16560	COG0242	peptide deformylase activity
BTL48_16570	COG0700	Nucleoside recognition
BTL48_16575	COG0469	pyruvate kinase activity
BTL48_16580	COG1929	Belongs to the glycerate kinase type-1 family
BTL48_16590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTL48_16595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL48_16600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BTL48_16610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTL48_16620	COG2154	pterin-4-alpha-carbinolamine dehydratase
BTL48_16625	COG2885	chlorophyll binding
BTL48_16635	COG0667	Aldo Keto reductase
BTL48_16645	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_16650	COG2801	Transposase and inactivated derivatives
BTL48_16665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL48_16670	COG0288	reversible hydration of carbon dioxide
BTL48_16690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL48_16705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTL48_16710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BTL48_16715	COG1414	Transcriptional regulator
BTL48_16720	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_16725	COG2031	fatty acid transporter
BTL48_16730	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL48_16740	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BTL48_16745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BTL48_16760	COG0129	dihydroxy-acid dehydratase activity
BTL48_16765	COG1609	Transcriptional regulator
BTL48_16785	COG4106	trans-aconitate 2-methyltransferase activity
BTL48_16805	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTL48_16830	COG2801	Transposase and inactivated derivatives
BTL48_16840	COG0163	prenyltransferase activity
BTL48_16845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BTL48_16850	COG2890	protein-(glutamine-N5) methyltransferase activity
BTL48_16855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTL48_16860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BTL48_16875	COG3712	iron ion homeostasis
BTL48_16905	COG0659	secondary active sulfate transmembrane transporter activity
BTL48_16925	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_16940	COG4774	siderophore transport
BTL48_16950	COG1595	DNA-templated transcription, initiation
BTL48_16965	COG0142	geranyltranstransferase activity
BTL48_16970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BTL48_16975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BTL48_16980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BTL48_16985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BTL48_17005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL48_17005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL48_17010	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BTL48_17020	COG0583	DNA-binding transcription factor activity
BTL48_17025	COG0861	Integral membrane protein TerC family
BTL48_17040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTL48_17045	COG0793	Belongs to the peptidase S41A family
BTL48_17050	COG4942	peptidase
BTL48_17055	COG0588	phosphoglycerate mutase activity
BTL48_17065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTL48_17070	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BTL48_17075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BTL48_17080	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_17095	COG2226	methyltransferase
BTL48_17100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BTL48_17105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTL48_17115	COG2204	response regulator
BTL48_17120	COG5000	phosphorelay sensor kinase activity
BTL48_17130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTL48_17130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL48_17185	COG1012	belongs to the aldehyde dehydrogenase family
BTL48_17205	COG0546	phosphoglycolate phosphatase activity
BTL48_17220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTL48_17225	COG0242	peptide deformylase activity
BTL48_17235	COG1522	sequence-specific DNA binding
BTL48_17240	COG2879	small protein
BTL48_17245	COG1966	Carbon starvation protein
BTL48_17275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL48_17280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL48_17285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTL48_17290	COG3181	Tripartite tricarboxylate transporter family receptor
BTL48_17330	COG0411	ABC transporter
BTL48_17355	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTL48_17390	COG0640	Transcriptional regulator
BTL48_17420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BTL48_17430	COG0735	belongs to the Fur family
BTL48_17435	COG2207	Transcriptional regulator
BTL48_17440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTL48_17445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BTL48_17450	COG0513	Belongs to the DEAD box helicase family
BTL48_17475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTL48_17490	COG1305	Transglutaminase-like
BTL48_17530	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTL48_17535	COG1950	PFAM Membrane protein of
BTL48_17540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BTL48_17560	COG0024	Methionine aminopeptidase
BTL48_17565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTL48_17575	COG1560	Kdo2-lipid A biosynthetic process
BTL48_17580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BTL48_17590	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BTL48_17625	COG0735	belongs to the Fur family
BTL48_17630	COG0523	cobalamin synthesis protein
BTL48_17635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTL48_17640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BTL48_17645	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BTL48_17655	COG2096	Adenosyltransferase
BTL48_17660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BTL48_17665	COG0321	lipoyl(octanoyl) transferase activity
BTL48_17675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL48_17680	COG1686	Belongs to the peptidase S11 family
BTL48_17705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTL48_17715	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BTL48_17725	COG0859	PFAM glycosyl transferase family 9
BTL48_17760	COG0477	Major facilitator Superfamily
BTL48_17775	COG3568	Endonuclease Exonuclease Phosphatase
BTL48_17780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BTL48_17810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL48_17815	COG1956	GAF domain-containing protein
BTL48_17820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL48_17835	COG2186	Transcriptional regulator
BTL48_17840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTL48_17855	COG1840	ABC-type Fe3 transport system, periplasmic component
BTL48_17860	COG0642	Histidine kinase
BTL48_17865	COG0745	RESPONSE REGULATOR receiver
BTL48_17895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTL48_17900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTL48_17905	COG1086	Polysaccharide biosynthesis protein
BTL48_17935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BTL48_17945	COG1028	Short-chain dehydrogenase reductase Sdr
BTL48_17950	COG1012	belongs to the aldehyde dehydrogenase family
BTL48_17955	COG2801	Transposase and inactivated derivatives
BTL48_17975	COG1522	sequence-specific DNA binding
BTL48_17980	COG3781	membrane
BTL48_17995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTL48_18025	COG2200	EAL domain
BTL48_18035	COG0592	DNA-directed DNA polymerase activity
BTL48_18040	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTL48_18045	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTL48_18050	COG0594	ribonuclease P activity
BTL48_18055	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BTL48_18060	COG0706	membrane insertase activity
BTL48_18065	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BTL48_18070	COG1473	amidohydrolase
BTL48_18075	COG4608	Belongs to the ABC transporter superfamily
BTL48_18080	COG0444	Belongs to the ABC transporter superfamily
BTL48_18085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL48_18090	COG0601	transmembrane transport
BTL48_18100	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BTL48_18105	COG1505	serine-type exopeptidase activity
BTL48_18115	COG0281	malic enzyme
BTL48_18115	COG0280	phosphate acetyltransferase
BTL48_18125	COG5002	protein histidine kinase activity
BTL48_18145	COG0436	Aminotransferase
BTL48_18150	COG1278	Cold shock