locus-tag class description B7O99_00015 ENOG4107QJE Chromosome Partitioning Protein B7O99_00025 ENOG4105FA0 parb-like partition protein B7O99_00030 ENOG4105HDK L-asparaginase B7O99_00050 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) B7O99_00060 ENOG410683Z Preprotein translocase SecE subunit B7O99_00070 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) B7O99_00075 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) B7O99_00080 ENOG4108VZM 50s ribosomal protein L10 B7O99_00085 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) B7O99_00095 ENOG4107QR0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) B7O99_00130 ENOG4105PGM cation diffusion facilitator family transporter B7O99_00140 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) B7O99_00145 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) B7O99_00155 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) B7O99_00165 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) B7O99_00170 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) B7O99_00175 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) B7O99_00180 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity B7O99_00185 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) B7O99_00190 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) B7O99_00195 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) B7O99_00200 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) B7O99_00205 ENOG41084PQ 50s ribosomal protein l29 B7O99_00210 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal B7O99_00230 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) B7O99_00235 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) B7O99_00240 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits B7O99_00245 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) B7O99_00250 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) B7O99_00255 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) B7O99_00260 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) B7O99_00265 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) B7O99_00270 ENOG4105VPB 50S ribosomal protein L30 B7O99_00280 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) B7O99_00285 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) B7O99_00295 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits B7O99_00300 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) B7O99_00305 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) B7O99_00310 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) B7O99_00315 ENOG4108ZT0 50S ribosomal protein l17 B7O99_00320 ENOG4107YU2 histidine triad (hIT) protein B7O99_00325 ENOG4105VF7 tolerance protein B7O99_00330 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) B7O99_00340 ENOG4105D52 delta-aminolevulinic acid dehydratase B7O99_00345 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) B7O99_00350 ENOG4106RE7 Cytochrome B7O99_00355 ENOG4105EBH Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity) B7O99_00360 ENOG4105CRE cytochrome C B7O99_00365 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) B7O99_00375 ENOG4105XQ6 frataxin-like protein B7O99_00380 ENOG4108JQC penicillin-binding protein 1A B7O99_00390 ENOG4105D49 3-dehydroquinate synthase B7O99_00405 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) B7O99_00410 ENOG4107RDB Major Facilitator B7O99_00455 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) B7O99_00460 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_00465 ENOG4105JNK Glycosyl transferase (Group 1 B7O99_00485 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component B7O99_00510 ENOG4107QP3 malate synthase g B7O99_00515 ENOG4108KWP DNA-binding transcriptional regulator GlcC B7O99_00535 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7O99_00540 ENOG4108ZGC gaf domain protein B7O99_00545 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7O99_00575 ENOG4107R7I amino acid B7O99_00605 ENOG4105C9M aspartyl-trna synthetase B7O99_00610 ENOG4105X23 Endonuclease Exonuclease phosphatase B7O99_00615 ENOG4105DZQ phospholipase D Transphosphatidylase B7O99_00635 ENOG4105C1B dTDP-glucose 4-6-dehydratase B7O99_00640 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase B7O99_00645 ENOG4105CAQ asparagine synthetase B7O99_00650 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) B7O99_00665 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) B7O99_00670 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) B7O99_00685 ENOG4105EY8 ABC transporter B7O99_00690 ENOG4105EY8 ABC transporter B7O99_00710 ENOG4105CAQ asparagine synthetase B7O99_00725 ENOG4105C1B dTDP-glucose 4-6-dehydratase B7O99_00740 ENOG4105CAQ asparagine synthetase B7O99_00750 ENOG4105CG5 Glycosyl transferase (Group 1 B7O99_00770 ENOG4107UU3 sucrose-phosphate synthase (EC 2.4.1.14) B7O99_00775 ENOG4105D3Q Sugar transferase B7O99_00780 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase B7O99_00790 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase B7O99_00795 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase B7O99_00800 ENOG4105J5G Transferase hexapeptide repeat containing protein B7O99_00810 ENOG4105D16 lipopolysaccharide heptosyltransferase i B7O99_00815 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase B7O99_00845 ENOG4105DHJ ABC, transporter B7O99_00865 ENOG4105DZ1 carboxypeptidase B7O99_00870 ENOG4105F0I Aminotransferase B7O99_00890 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase B7O99_00905 ENOG4108WBT adenosyltransferase B7O99_00920 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) B7O99_00925 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters B7O99_00930 ENOG4105CKI cobalamin synthesis protein B7O99_00935 ENOG4105MYN Zinc uptake regulation protein B7O99_00940 ENOG4105DIK (ABC) transporter B7O99_00945 ENOG4105CC5 ABC transporter B7O99_00950 ENOG4105DSE periplasmic solute binding protein B7O99_00960 ENOG4105D7X high-affinity nickel-transporter B7O99_00965 ENOG4105UGU tonB-dependent Receptor B7O99_00970 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) B7O99_00980 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) B7O99_00985 ENOG4105D1S lipid A biosynthesis B7O99_00995 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP B7O99_01005 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) B7O99_01010 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) B7O99_01015 ENOG41086DT Membrane protein of unknown function B7O99_01020 ENOG4105SYT Methylenetetrahydrofolate reductase B7O99_01025 ENOG4105DUM transcriptional regulator, lysR family B7O99_01035 ENOG4105CSH Transporter B7O99_01045 ENOG4107SC1 transglycosylase B7O99_01060 ENOG4105C1J atp-dependent rna helicase B7O99_01070 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 B7O99_01075 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) B7O99_01090 ENOG41090R7 Ferric uptake B7O99_01100 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) B7O99_01110 ENOG4105E2K Glycosyl transferase (Group 1 B7O99_01125 ENOG4105CSR polyphosphate kinase 2 B7O99_01135 ENOG41080HT Transcriptional regulator, arsr family B7O99_01150 ENOG4105DZS Phenylacetate-CoA ligase B7O99_01155 ENOG4108IV0 ABC, transporter B7O99_01170 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_01175 ENOG4105C0Z ABC transporter B7O99_01195 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) B7O99_01210 ENOG4105DFA alanine racemase domain protein B7O99_01215 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7O99_01220 ENOG4107QXX ABC transporter B7O99_01230 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase B7O99_01235 ENOG4105C79 DNA protecting protein DprA B7O99_01240 ENOG4105F7P transcriptional regulator AsnC family B7O99_01250 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) B7O99_01265 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 B7O99_01275 ENOG4108URH decarboxylase B7O99_01290 ENOG41084KP 4-oxalocrotonate tautomerase B7O99_01295 ENOG4105CJP fad dependent oxidoreductase B7O99_01330 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B B7O99_01340 ENOG4105ES5 Histidine kinase B7O99_01345 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family B7O99_01350 ENOG4105C1A potassium transporter peripheral membrane B7O99_01355 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) B7O99_01395 ENOG4108UAU isochorismatase B7O99_01420 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_01450 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component B7O99_01460 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_01465 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) B7O99_01470 ENOG4106T9E Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) B7O99_01495 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) B7O99_01500 ENOG4105VW4 glutaredoxin 3 B7O99_01505 ENOG4105C72 UPF0176 protein B7O99_01515 ENOG41063SB peptidase B7O99_01520 ENOG4105CN1 protease B7O99_01525 ENOG4105D06 uba thif-type nad fad binding protein B7O99_01540 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) B7O99_01545 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) B7O99_01550 ENOG4105S7Q restriction endonuclease B7O99_01580 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control B7O99_01585 ENOG4105K46 50S ribosomal protein l27 B7O99_01590 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) B7O99_01600 ENOG4105EAH synthase B7O99_01610 ENOG4105RQF LysR family Transcriptional regulator B7O99_01620 ENOG4107TYC hydantoinase B oxoprolinase B7O99_01625 ENOG4105DDR sarcosine oxidase (Beta subunit) B7O99_01630 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_01640 ENOG41090Q8 at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP B7O99_01650 ENOG4107VZP Hemolysin-type calcium-binding repeat 2 copies family protein B7O99_01655 ENOG4108JJA ABC, transporter B7O99_01675 ENOG4107RP9 extracellular solute-binding protein, family 3 B7O99_01680 ENOG4105EAD ABC transporter B7O99_01685 ENOG4105DRP amino acid AbC transporter B7O99_01690 ENOG4105CDA abc transporter atp-binding protein B7O99_01710 ENOG4105CHR reductase B7O99_01720 ENOG4108WYP Transcriptional regulator B7O99_01735 ENOG4105DRR Transcriptional regulator, GntR family B7O99_01740 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein B7O99_01745 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_01755 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component B7O99_01765 ENOG4107UWC ABC, transporter B7O99_01785 ENOG4106P55 Transcriptional regulator B7O99_01790 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_01795 ENOG4105CI0 Citrate lyase B7O99_01800 ENOG4105FDP GntR family transcriptional regulator B7O99_01820 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_01845 ENOG4107F9Y LysR family transcriptional regulator B7O99_01855 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase B7O99_01865 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_01875 ENOG4105C0Z ABC transporter B7O99_01880 ENOG4108IV0 ABC, transporter B7O99_01885 ENOG4105H9W Short-chain dehydrogenase reductase Sdr B7O99_01895 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr B7O99_01900 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7O99_01925 ENOG4105CK6 Two component transcriptional regulator (Winged helix family B7O99_01955 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) B7O99_01965 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) B7O99_01975 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase B7O99_01985 ENOG4107BVJ 4,5-dihydroxyphthalate decarboxylase B7O99_02035 ENOG4108IV0 ABC, transporter B7O99_02040 ENOG4105C0Z ABC transporter B7O99_02045 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_02050 ENOG4108HWV )-transporter B7O99_02065 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7O99_02090 ENOG4105F2Z 3-oxoadipate enol-lactonase B7O99_02105 ENOG4107QNJ CoA-transferase subunit B B7O99_02115 ENOG4107HP6 Transcriptional regulator B7O99_02120 ENOG4105CHR reductase B7O99_02125 ENOG4105CRW Short chain fatty acid transporter B7O99_02130 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7O99_02170 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase B7O99_02175 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_02180 ENOG4105F2M alpha beta hydrolase fold-3 domain protein B7O99_02190 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) B7O99_02200 ENOG4105C01 Dihydroxy-acid dehydratase B7O99_02220 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7O99_02235 ENOG4105CBN LysR family transcriptional regulator B7O99_02240 ENOG4105IPI Membrane B7O99_02250 ENOG4107SVH Potassium channel protein B7O99_02255 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) B7O99_02265 ENOG4105EPW hflc protein B7O99_02285 ENOG4105EJC lysr family transcriptional regulator B7O99_02325 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_02330 ENOG4107258 Transcriptional regulator B7O99_02335 ENOG4108VUG Enoyl-CoA hydratase B7O99_02350 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family B7O99_02355 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_02360 ENOG4105DND Transcriptional regulator B7O99_02370 ENOG4105IYB L-carnitine dehydratase bile acid-inducible protein F B7O99_02385 ENOG4108UQ8 endoribonuclease L-psp B7O99_02395 ENOG4105CRW Short chain fatty acid transporter B7O99_02425 ENOG4105VEQ Cold shock protein B7O99_02430 ENOG4105DND Transcriptional regulator B7O99_02440 ENOG4105CBG Sulfatase B7O99_02455 ENOG4105CI2 imidazolone-5-propionate hydrolase B7O99_02460 ENOG4105CKI cobalamin synthesis protein B7O99_02535 ENOG4108TGY Glutathione S-transferase B7O99_02550 ENOG4105CRE cytochrome C B7O99_02555 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY B7O99_02560 ENOG4109066 lysm domain bon superfamily protein B7O99_02565 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) B7O99_02575 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) B7O99_02585 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_02590 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase B7O99_02625 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_02680 ENOG4106KR7 LysR family Transcriptional regulator B7O99_02690 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha B7O99_02695 ENOG4105E39 Enoyl-CoA hydratase B7O99_02710 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_02725 ENOG4105C7K acetolactate synthase B7O99_02745 ENOG4105J4Q Transcriptional regulator B7O99_02765 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_02770 ENOG4105ETE Transcriptional regulator (LacI family B7O99_02800 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase B7O99_02805 ENOG4105E39 Enoyl-CoA hydratase B7O99_02810 ENOG4105C0A alcohol dehydrogenase B7O99_02820 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_02830 ENOG4108KB2 LysR family Transcriptional regulator B7O99_02845 ENOG4105C1G acyl-Coa dehydrogenase B7O99_02860 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) B7O99_02865 ENOG4105DUM transcriptional regulator, lysR family B7O99_02870 ENOG4107EFR Flavocytochrome c B7O99_02885 ENOG4108IV0 ABC, transporter B7O99_02890 ENOG4105C0Z ABC transporter B7O99_02905 ENOG41083Z3 extracellular ligand-binding receptor B7O99_02910 ENOG4108W9H Tetr family transcriptional regulator B7O99_02930 ENOG4105CHR reductase B7O99_02935 ENOG4105C1G acyl-Coa dehydrogenase B7O99_02940 ENOG4105CHR reductase B7O99_02945 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_02955 ENOG4108IPT Naphthoate synthase B7O99_02960 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_02970 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein B7O99_02980 ENOG4105DJG MaoC domain protein dehydratase B7O99_02995 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_03025 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_03040 ENOG4108IV0 ABC, transporter B7O99_03045 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7O99_03060 ENOG4105CYC Transferase B7O99_03065 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_03080 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) B7O99_03095 ENOG4105CHR reductase B7O99_03100 ENOG4105CHU acetyl-coa acetyltransferase B7O99_03105 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) B7O99_03115 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_03120 ENOG4105DND Transcriptional regulator B7O99_03125 ENOG4105C1G acyl-Coa dehydrogenase B7O99_03135 ENOG4105C10 Electron transfer flavoprotein B7O99_03140 ENOG4108M9J MaoC like domain protein B7O99_03160 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_03165 ENOG4108RZE Tetr family transcriptional regulator B7O99_03175 ENOG4105E39 Enoyl-CoA hydratase B7O99_03190 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase B7O99_03195 ENOG4105E39 Enoyl-CoA hydratase B7O99_03200 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_03210 ENOG4105C0A alcohol dehydrogenase B7O99_03215 ENOG4108UKI Enoyl-CoA hydratase B7O99_03235 ENOG4105C26 Dehydrogenase B7O99_03240 ENOG4108UZX fmn reductase B7O99_03245 ENOG4108I05 Binding-protein-dependent transport systems, inner membrane component B7O99_03265 ENOG4107HP6 Transcriptional regulator B7O99_03270 ENOG4105IJJ transcriptional regulator, crp fnr family B7O99_03275 ENOG4105CHR reductase B7O99_03305 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_03325 ENOG4105CGU Enoyl-CoA hydratase B7O99_03335 ENOG4105C1G acyl-Coa dehydrogenase B7O99_03340 ENOG4105E39 Enoyl-CoA hydratase B7O99_03345 ENOG4105CHU acetyl-coa acetyltransferase B7O99_03365 ENOG4105ETT transcriptional Regulator, LysR family B7O99_03370 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) B7O99_03385 ENOG4108K3A Glutathione S-transferase B7O99_03400 ENOG4105C6F GntR Family Transcriptional Regulator B7O99_03405 ENOG4105C26 Dehydrogenase B7O99_03410 ENOG4105C28 cystathionine B7O99_03430 ENOG4107QRP cobalamin biosynthesis protein CobW B7O99_03450 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7O99_03455 ENOG4105CHM Aminotransferase B7O99_03460 ENOG4105EAB amino acid AbC transporter B7O99_03465 ENOG4105E5Q amino acid AbC transporter B7O99_03475 ENOG4105CH2 amidohydrolase B7O99_03480 ENOG41069M3 Transcriptional regulator B7O99_03490 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7O99_03505 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_03550 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_03565 ENOG4105DKK Benzoate B7O99_03580 ENOG4105DUM transcriptional regulator, lysR family B7O99_03590 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase B7O99_03615 ENOG41064HX Suppressor of fused protein (SUFU) B7O99_03675 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit B7O99_03700 ENOG4106VK6 Flagellar motor protein B7O99_03730 ENOG4105F4K antigen 43 B7O99_03740 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) B7O99_03745 ENOG4105E0C molybdate abc transporter B7O99_03750 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein B7O99_03795 ENOG4105C8Y Acetylornithine aminotransferase B7O99_03855 ENOG4105DHP deoxycytidine triphosphate deaminase B7O99_03880 ENOG4105CXN decarboxylase B7O99_03885 ENOG4105CBX hi0933 family B7O99_03905 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) B7O99_03930 ENOG4105E39 Enoyl-CoA hydratase B7O99_03950 ENOG4108JQ6 ABC transporter B7O99_03970 ENOG4105C26 Dehydrogenase B7O99_03975 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) B7O99_03990 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) B7O99_04000 ENOG4108S0N Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity) B7O99_04005 ENOG4107UKG Glycosyl transferase, family 4 B7O99_04010 ENOG4107QQG Dehydrogenase B7O99_04025 ENOG4105CG5 Glycosyl transferase (Group 1 B7O99_04035 ENOG4107XU6 Glycosyl transferase (Group 1 B7O99_04040 ENOG4108KMV Glycosyl transferase (Group 1 B7O99_04045 ENOG4105CGN Glycosyl transferase (Group 1 B7O99_04050 ENOG4107QP8 phosphohexose isomerase B7O99_04065 ENOG4105CQB FAD linked oxidase domain protein B7O99_04070 ENOG4105XJC Two component transcriptional regulator (Winged helix family B7O99_04075 ENOG4105DHQ Histidine kinase B7O99_04080 ENOG4105E0M Sulfatase B7O99_04090 ENOG4105F1J Homogentisate 1,2-dioxygenase B7O99_04110 ENOG4105E2Q 3-(3-hydroxy-phenyl)propionate hydroxylase B7O99_04125 ENOG4105DJQ tetratricopeptide tpr_2 repeat protein B7O99_04145 ENOG4105C5T Phosphoribosyl pyrophosphate synthase B7O99_04150 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) B7O99_04155 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) B7O99_04165 ENOG4105C3G gtp-binding protein B7O99_04180 ENOG4108KXV response regulator B7O99_04190 ENOG4108W9H Tetr family transcriptional regulator B7O99_04200 ENOG4105DXI Major Facilitator superfamily B7O99_04225 ENOG4105C6K Malic enzyme B7O99_04245 ENOG4108JQ6 ABC transporter B7O99_04260 ENOG4105F04 LysR family Transcriptional regulator B7O99_04275 ENOG41082BM Transcriptional regulator, arsr family B7O99_04290 ENOG4105DKK Benzoate B7O99_04295 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding B7O99_04300 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) B7O99_04305 ENOG4106H78 methyltransferase B7O99_04350 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) B7O99_04355 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) B7O99_04360 ENOG4107YIM Involved in the transcription termination process (By similarity) B7O99_04365 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) B7O99_04370 ENOG4108ZAI phosphatidylglycerophosphatase a B7O99_04375 ENOG4108I62 cina-like protein B7O99_04380 ENOG4105SKN orotidine 5''-phosphate decarboxylase B7O99_04385 ENOG4105CEP NADH dehydrogenase B7O99_04390 ENOG41080IJ Diacylglycerol kinase B7O99_04395 ENOG4107S2Z UPF0761 membrane protein B7O99_04405 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) B7O99_04410 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) B7O99_04430 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein B7O99_04440 ENOG4105DUM transcriptional regulator, lysR family B7O99_04445 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein B7O99_04455 ENOG4107HP6 Transcriptional regulator B7O99_04470 ENOG4105CHJ isochorismatase hydrolase B7O99_04485 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) B7O99_04500 ENOG4105C1G acyl-Coa dehydrogenase B7O99_04505 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_04515 ENOG4107RSM transcriptional regulator B7O99_04545 ENOG4105CN8 Transcriptional regulator B7O99_04550 ENOG4108K0B C-di-gmp phosphodiesterase B7O99_04575 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_04605 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7O99_04610 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_04615 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_04620 ENOG4105BZU Histidine kinase B7O99_04635 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_04640 ENOG4105CSU acyl-Coa dehydrogenase B7O99_04680 ENOG4108Z9Z response to DNA damage stimulus B7O99_04695 ENOG4105GRZ Ycii-related protein B7O99_04700 ENOG4105FDP GntR family transcriptional regulator B7O99_04720 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7O99_04725 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_04730 ENOG4105E39 Enoyl-CoA hydratase B7O99_04755 ENOG41061TZ Short-chain dehydrogenase reductase Sdr B7O99_04760 ENOG41069M3 Transcriptional regulator B7O99_04765 ENOG4105CP9 extracellular ligand-binding receptor B7O99_04780 ENOG4107Z5Z endoribonuclease L-PSP B7O99_04785 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_04795 ENOG4105C0Z ABC transporter B7O99_04800 ENOG4108IV0 ABC, transporter B7O99_04805 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7O99_04810 ENOG4105HEI LysR family (Transcriptional regulator B7O99_04820 ENOG4107Y2X deaminase B7O99_04825 ENOG4105DJ2 Major Facilitator Superfamily B7O99_04830 ENOG4108R6K riboflavin synthase, subunit alpha B7O99_04840 ENOG4108XM1 transcriptional regulator AsnC family B7O99_04850 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_04860 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component B7O99_04900 ENOG4105EST Metal Dependent Phosphohydrolase B7O99_04910 ENOG4105CHJ isochorismatase hydrolase B7O99_04940 ENOG4108JJA ABC, transporter B7O99_04950 ENOG4105DFG type I secretion outer membrane protein B7O99_04955 ENOG4105BZ8 glutamate synthase B7O99_04965 ENOG4107R5R arsenical pump membrane protein B7O99_04975 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_04990 ENOG4105C1G acyl-Coa dehydrogenase B7O99_04995 ENOG4105F6U Short-chain dehydrogenase reductase Sdr B7O99_05000 ENOG4105KPY Small multidrug resistance protein B7O99_05005 ENOG4108IND Tetr family transcriptional regulator B7O99_05025 ENOG4105C8Q Methyl-accepting chemotaxis B7O99_05040 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) B7O99_05065 ENOG4105C26 Dehydrogenase B7O99_05075 ENOG41060WC Enoyl-CoA hydratase B7O99_05085 ENOG410620I Diguanylate cyclase B7O99_05105 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7O99_05110 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_05135 ENOG4105NSG hemerythrin hhe cation binding domain protein B7O99_05150 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) B7O99_05170 ENOG4105C4M (Ubiquinol oxidase) subunit I B7O99_05175 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii B7O99_05185 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7O99_05195 ENOG4105DB1 molybdopterin oxidoreductase B7O99_05200 ENOG4106WHD Tetrathionate reductase B7O99_05205 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein B7O99_05215 ENOG4105CPT Alpha beta hydrolase B7O99_05220 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) B7O99_05245 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) B7O99_05255 ENOG4105JSC dimethylmenaquinone methyltransferase B7O99_05270 ENOG4105EA8 2-Nitropropane dioxygenase B7O99_05275 ENOG4105EGI Transcriptional regulator B7O99_05285 ENOG4106AXJ AraC family transcriptional regulator B7O99_05300 ENOG4105CSR polyphosphate kinase 2 B7O99_05315 ENOG4105C7B Threonine dehydratase B7O99_05345 ENOG4105C5Q Transcriptional regulator B7O99_05360 ENOG4105F52 Transcriptional regulator B7O99_05385 ENOG4108UYB regulatoR B7O99_05390 ENOG4105E2S oxidase) subunit II B7O99_05395 ENOG4105BZ9 Cytochrome C oxidase, subunit I B7O99_05400 ENOG4105CCU oxidase (Subunit III) B7O99_05405 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) B7O99_05410 ENOG4105YVS arsR family transcriptional regulator B7O99_05445 ENOG4105E0K tonB-dependent siderophore receptor B7O99_05500 ENOG4105CHR reductase B7O99_05510 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) B7O99_05515 ENOG4105CCU oxidase (Subunit III) B7O99_05520 ENOG4105BZ9 Cytochrome C oxidase, subunit I B7O99_05525 ENOG4105E2S oxidase) subunit II B7O99_05530 ENOG4105CSH Transporter B7O99_05545 ENOG4107AQZ Membrane B7O99_05550 ENOG41068KF Universal stress protein B7O99_05565 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) B7O99_05580 ENOG4108IEG Formate dehydrogenase Alpha subunit B7O99_05600 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) B7O99_05605 ENOG4105CVM Molybdenum cofactor synthesis domain protein B7O99_05610 ENOG4108RIR Molybdenum cofactor biosynthesis protein B7O99_05615 ENOG4108ZAF Molybdopterin B7O99_05620 ENOG4105M00 molybdopterin converting factor, subunit 1 B7O99_05635 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) B7O99_05655 ENOG4108TZV Membrane B7O99_05660 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) B7O99_05700 ENOG4107QM5 aconitate hydratase B7O99_05705 ENOG4105CD3 dihydroorotase B7O99_05710 ENOG4108UAU isochorismatase B7O99_05715 ENOG4105CKI cobalamin synthesis protein B7O99_05745 ENOG4105DRR Transcriptional regulator, GntR family B7O99_05765 ENOG4107SET aldo keto reductase B7O99_05775 ENOG4108JU5 Magnesium and cobalt efflux protein B7O99_05785 ENOG4105C9A Phoh family B7O99_05800 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) B7O99_05805 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) B7O99_05810 ENOG4105VIE preprotein translocase, subunit YajC B7O99_05815 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) B7O99_05825 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase B7O99_05830 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) B7O99_05840 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) B7O99_05870 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division B7O99_05875 ENOG4105CHM Aminotransferase B7O99_05885 ENOG4105C6K Malic enzyme B7O99_05900 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) B7O99_05905 ENOG4105CV1 Transketolase (EC 2.2.1.1) B7O99_05910 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase B7O99_05920 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH B7O99_05925 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) B7O99_05940 ENOG4108SHQ Glutathione S-transferase B7O99_05970 ENOG4108UMN azlc family B7O99_05980 ENOG4105CJ3 phosphate transporter B7O99_05985 ENOG4108RIR Molybdenum cofactor biosynthesis protein B7O99_05995 ENOG4105DR5 peptidase B7O99_06005 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) B7O99_06025 ENOG4105IW1 AmiS UreI transporter B7O99_06045 ENOG4105D2N Aldolase B7O99_06055 ENOG4105C8V SAICAR synthetase B7O99_06075 ENOG4105RXK Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) B7O99_06080 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) B7O99_06085 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit B7O99_06090 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) B7O99_06100 ENOG4108FUF Transcriptional regulator, IclR family B7O99_06105 ENOG4105CYW agmatinase B7O99_06115 ENOG4105E5Q amino acid AbC transporter B7O99_06120 ENOG4105CDA abc transporter atp-binding protein B7O99_06135 ENOG4105C1G acyl-Coa dehydrogenase B7O99_06140 ENOG4105C7K acetolactate synthase B7O99_06145 ENOG4105ETT transcriptional Regulator, LysR family B7O99_06150 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) B7O99_06155 ENOG4108Z66 YbaK ebsC protein B7O99_06160 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) B7O99_06170 ENOG41061WM D-Alanyl-D-Alanine B7O99_06180 ENOG4107RGD Major Facilitator superfamily B7O99_06190 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation B7O99_06200 ENOG4107QMP dna polymerase iii subunits gamma and tau B7O99_06210 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) B7O99_06215 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_06220 ENOG4105D2X ABC transporter substrate-binding protein B7O99_06230 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component B7O99_06235 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) B7O99_06240 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain B7O99_06245 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain B7O99_06255 ENOG4108YZN class I peptide chain release factor B7O99_06275 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7O99_06305 ENOG4107EFR Flavocytochrome c B7O99_06315 ENOG4108QIU Dehydrogenase B7O99_06330 ENOG4105E98 transcriptional regulator DeoR family B7O99_06340 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_06350 ENOG4105EB1 binding-protein-dependent transport systems inner membrane Component B7O99_06375 ENOG4105EW9 transcriptional regulator AsnC family B7O99_06385 ENOG4107RH8 nuclease SbcCD subunit D B7O99_06400 ENOG4105D65 subunit l B7O99_06405 ENOG4108ZE9 Monovalent cation H antiporter subunit C B7O99_06410 ENOG4107R4Z monovalent cation h antiporter subunit d B7O99_06415 ENOG4105SC1 monovalent cation H antiporter subunit E B7O99_06420 ENOG4105W4C monovalent cation H antiporter subunit F B7O99_06440 ENOG4108Z6B deaminase B7O99_06445 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A B7O99_06450 ENOG4105E39 Enoyl-CoA hydratase B7O99_06455 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_06465 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_06470 ENOG4105C5H ABC transporter B7O99_06500 ENOG41080RH Thioredoxin B7O99_06505 ENOG4105DEN Luciferase family B7O99_06510 ENOG4105C7N Xanthine uracil vitamin C permease B7O99_06520 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) B7O99_06525 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) B7O99_06530 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) B7O99_06535 ENOG4108K5P (LipO)protein B7O99_06570 ENOG4105EHV domain protein B7O99_06580 ENOG4105D6S protein involved in catabolism of external DNA B7O99_06585 ENOG4107T6V glycerophosphoryl diester phosphodiesterase B7O99_06590 ENOG4105EIN peptidylprolyl cis-trans isomerase B7O99_06595 ENOG4108UJV acyl-CoA thioesterase i B7O99_06600 ENOG4108I0Y (ABC) transporter B7O99_06610 ENOG4105EGI Transcriptional regulator B7O99_06640 ENOG4105CFM UPF0317 protein B7O99_06655 ENOG4108WQH regulatoR B7O99_06660 ENOG4108QZZ filamentous hemagglutinin B7O99_06670 ENOG4105GQR Chaperone B7O99_06680 ENOG41074HU Fimbrial adhesin B7O99_06685 ENOG4108YH7 hemolysin B7O99_06700 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_06705 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_06725 ENOG4107NQ8 LysR family Transcriptional regulator B7O99_06745 ENOG4107R0W ABC transporter B7O99_06750 ENOG4105E5Q amino acid AbC transporter B7O99_06755 ENOG4105CDA abc transporter atp-binding protein B7O99_06760 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) B7O99_06765 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) B7O99_06770 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) B7O99_06780 ENOG41090Y2 cytochrome C B7O99_06785 ENOG41061TZ Short-chain dehydrogenase reductase Sdr B7O99_06790 ENOG4105K4H Nlp p60 protein B7O99_06795 ENOG4105FYV Amp nucleosidase B7O99_06830 ENOG4105DUM transcriptional regulator, lysR family B7O99_06840 ENOG4105BZU Histidine kinase B7O99_06850 ENOG4105CSA Coproporphyrinogen iii oxidase B7O99_06855 ENOG4105C5F glutamine synthetase B7O99_06860 ENOG4105CUX Signal transduction histidine kinase B7O99_06865 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family B7O99_06870 ENOG4105EQ1 Transcriptional regulator B7O99_06880 ENOG4105EUB pirin domain protein B7O99_06885 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_06895 ENOG4107QKW extracellular solute-binding protein family 1 B7O99_06900 ENOG4105DP0 ferredoxin-NADP reductase B7O99_06905 ENOG4105HEI LysR family (Transcriptional regulator B7O99_06910 ENOG4105F27 Major Facilitator B7O99_06915 ENOG4105CV8 reductase B7O99_06925 ENOG4105KME endoribonuclease L-psp B7O99_06930 ENOG4105CB5 ATP-dependent DNA helicase recG B7O99_06935 ENOG4105C5Q Transcriptional regulator B7O99_06940 ENOG4105JQN Transcriptional regulator B7O99_06945 ENOG4105C26 Dehydrogenase B7O99_06965 ENOG4105K64 Glycosyl transferase, family 2 B7O99_06985 ENOG4107TAE Glycosyl transferase (Group 1 B7O99_07000 ENOG4107QQG Dehydrogenase B7O99_07010 ENOG4105E12 capsule polysaccharide B7O99_07015 ENOG41084CK capsule polysaccharide B7O99_07020 ENOG4108W6C Dehydrogenase B7O99_07045 ENOG4105CP9 extracellular ligand-binding receptor B7O99_07060 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component B7O99_07065 ENOG4105BZ7 extracellular solute-binding protein family 1 B7O99_07070 ENOG4105II7 pyrroline-5-carboxylate reductase B7O99_07075 ENOG4105EX9 Membrane B7O99_07080 ENOG4105CP9 extracellular ligand-binding receptor B7O99_07085 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_07090 ENOG4105CF8 branched-chain amino acid ABC transporter, permease B7O99_07095 ENOG4105C0Z ABC transporter B7O99_07100 ENOG4108IV0 ABC, transporter B7O99_07110 ENOG4108K3A Glutathione S-transferase B7O99_07115 ENOG4105D8V Glucose sorbosone dehydrogenase B7O99_07155 ENOG4105D01 (LipO)protein B7O99_07180 ENOG4105DF9 Lipoate-protein, ligase B7O99_07195 ENOG4105CYM Glutathione S-transferase B7O99_07200 ENOG4108V06 Glutathione peroxidase B7O99_07215 ENOG4105WAP TPR repeat-containing protein B7O99_07240 ENOG4108VGI doxx family B7O99_07245 ENOG4105D4Y metalloprotease B7O99_07255 ENOG4105CPC Aldo Keto reductase B7O99_07260 ENOG41068KF Universal stress protein B7O99_07275 ENOG4105CSW GntR family transcriptional regulator B7O99_07280 ENOG4105DFA alanine racemase domain protein B7O99_07285 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) B7O99_07300 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) B7O99_07350 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) B7O99_07360 ENOG4105C5Q Transcriptional regulator B7O99_07390 ENOG4108JQ6 ABC transporter B7O99_07445 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) B7O99_07460 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) B7O99_07465 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) B7O99_07470 ENOG4105C9B Cysteine desulfurase B7O99_07480 ENOG4105DHQ Histidine kinase B7O99_07485 ENOG4105XJC Two component transcriptional regulator (Winged helix family B7O99_07500 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) B7O99_07515 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) B7O99_07520 ENOG4105CUT histidyl-tRNA synthetase B7O99_07525 ENOG4105N21 Membrane B7O99_07530 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) B7O99_07535 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) B7O99_07545 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) B7O99_07550 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) B7O99_07555 ENOG4107QJR hflk protein B7O99_07560 ENOG4105EPW hflc protein B7O99_07565 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) B7O99_07575 ENOG4108UGV hypoxanthine phosphoribosyltransferase B7O99_07580 ENOG4105VCC 30S ribosomal protein S21 B7O99_07635 ENOG4108IV0 ABC, transporter B7O99_07640 ENOG4105C0Z ABC transporter B7O99_07645 ENOG4105CF8 branched-chain amino acid ABC transporter, permease B7O99_07650 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_07655 ENOG4105CP9 extracellular ligand-binding receptor B7O99_07660 ENOG4105FUY alpha subunit B7O99_07665 ENOG4108SBK dioxygenase, subunit beta B7O99_07670 ENOG4105E39 Enoyl-CoA hydratase B7O99_07675 ENOG4105CHR reductase B7O99_07680 ENOG4107Z7P Ferredoxin B7O99_07685 ENOG410846T CoA-transferase family III B7O99_07695 ENOG4105DZS Phenylacetate-CoA ligase B7O99_07700 ENOG4105CHU acetyl-coa acetyltransferase B7O99_07710 ENOG4108NVI B7O99_07720 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_07735 ENOG4105C26 Dehydrogenase B7O99_07740 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_07760 ENOG4108M8H domain protein B7O99_07770 ENOG4108JU7 Transcriptional regulator B7O99_07800 ENOG4108IQI permease B7O99_07820 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_07825 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit B7O99_07830 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase B7O99_07845 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component B7O99_07850 ENOG4105F38 ABC transporter, permease B7O99_07865 ENOG4105J4Q Transcriptional regulator B7O99_07870 ENOG4105H9W Short-chain dehydrogenase reductase Sdr B7O99_07880 ENOG4105FDP GntR family transcriptional regulator B7O99_07885 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_07910 ENOG4105DDW LysR family Transcriptional regulator B7O99_07930 ENOG4105CNN ABC, transporter B7O99_07940 ENOG4105ERH Fumarylacetoacetate hydrolase B7O99_07950 ENOG4105CI2 imidazolone-5-propionate hydrolase B7O99_07955 ENOG4106HB6 Alpha beta hydrolase B7O99_07980 ENOG4108ZCF integral membrane protein B7O99_08000 ENOG4105E6M Sulphatase-modifying factor protein B7O99_08040 ENOG4105ENH Sulfatase B7O99_08060 ENOG4105WH1 Two component transcriptional regulator luxr family B7O99_08070 ENOG4105W08 virulence gene repressor rsal B7O99_08075 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system B7O99_08080 ENOG4108K3A Glutathione S-transferase B7O99_08095 ENOG41061MV Arylsulfatase B7O99_08110 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_08115 ENOG4105CHU acetyl-coa acetyltransferase B7O99_08135 ENOG4107RSM transcriptional regulator B7O99_08165 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7O99_08175 ENOG4105C0A alcohol dehydrogenase B7O99_08200 ENOG4105DUM transcriptional regulator, lysR family B7O99_08205 ENOG4105CAU Arsenical resistance protein, ArsH B7O99_08235 ENOG4105CHR reductase B7O99_08265 ENOG4107QX8 SPFH domain, Band 7 family protein B7O99_08300 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) B7O99_08305 ENOG41060IM Heme exporter protein B7O99_08320 ENOG4105DA4 cytochrome c-type biogenesis protein B7O99_08325 ENOG4107QX9 Thiol disulfide interChange protein B7O99_08330 ENOG4105KWW Biogenesis protein B7O99_08335 ENOG4108M1T Cytochrome c-type biogenesis protein B7O99_08345 ENOG4105KME endoribonuclease L-psp B7O99_08355 ENOG4105CMJ mandelate racemase muconate lactonizing B7O99_08375 ENOG4105ETE Transcriptional regulator (LacI family B7O99_08390 ENOG4105HEI LysR family (Transcriptional regulator B7O99_08410 ENOG4105NTW Transcriptional regulator B7O99_08420 ENOG4105X23 Endonuclease Exonuclease phosphatase B7O99_08430 ENOG4107UXM Membrane B7O99_08445 ENOG4105CEV competence damage-inducible protein B7O99_08465 ENOG4105TNS Conserved Protein B7O99_08470 ENOG4105FDF Could be involved in DNA repair (By similarity) B7O99_08480 ENOG4105CYX Short-chain dehydrogenase reductase Sdr B7O99_08540 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family B7O99_08545 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family B7O99_08565 ENOG4105F0N pyrophosphate phospho-hydrolase B7O99_08585 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) B7O99_08590 ENOG4108ZCF integral membrane protein B7O99_08595 ENOG4108ZCF integral membrane protein B7O99_08600 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha B7O99_08605 ENOG4105CMV Succinyl-CoA synthetase subunit beta B7O99_08615 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) B7O99_08620 ENOG4105DZ2 Transcriptional regulator B7O99_08625 ENOG4108004 Modulates RecA activity (By similarity) B7O99_08630 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) B7O99_08640 ENOG4105DHQ Histidine kinase B7O99_08645 ENOG4105CSH Transporter B7O99_08650 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7O99_08655 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_08670 ENOG4105CHR reductase B7O99_08685 ENOG4105CHU acetyl-coa acetyltransferase B7O99_08690 ENOG4105ETT transcriptional Regulator, LysR family B7O99_08695 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_08710 ENOG4105CXT aspartate transcarbamylase B7O99_08750 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7O99_08765 ENOG4108RYR transcriptional regulator AsnC family B7O99_08775 ENOG4108J4B Beta-lactamase B7O99_08790 ENOG4106R49 Methyltransferase B7O99_08815 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) B7O99_08830 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) B7O99_08835 ENOG4105VJV 50s ribosomal protein L35 B7O99_08840 ENOG4105C0P Mg chelatase subunit ChlI B7O99_08845 ENOG4105W0Z cytoplasmic protein B7O99_08850 ENOG4108YZA Nitrogen regulatory protein pii B7O99_08855 ENOG4105BZU Histidine kinase B7O99_08860 ENOG4108P8G outer membrane autotransporter barrel B7O99_08875 ENOG41060BG Tetr family transcriptional regulator B7O99_08885 ENOG4108IV0 ABC, transporter B7O99_08890 ENOG4105C0Z ABC transporter B7O99_08895 ENOG4105CF8 branched-chain amino acid ABC transporter, permease B7O99_08900 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_08910 ENOG4105C26 Dehydrogenase B7O99_08920 ENOG4105DY2 Paraquat-inducible protein b B7O99_08925 ENOG4105F1S paraquat-inducible protein a B7O99_08930 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit B7O99_08935 ENOG4108JQB penicillin-binding protein 1C B7O99_08945 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) B7O99_08950 ENOG4105VEQ Cold shock protein B7O99_08970 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) B7O99_08975 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) B7O99_08985 ENOG4109015 Biopolymer transport protein exbD tolR B7O99_08990 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) B7O99_08995 ENOG4105W49 UPF0434 protein B7O99_09015 ENOG4105CJR Integral membrane protein (MviN B7O99_09025 ENOG41082GY Binds directly to 16S ribosomal RNA (By similarity) B7O99_09045 ENOG4105DG4 malate L-lactate dehydrogenase B7O99_09050 ENOG4107YCY Transcriptional regulator B7O99_09070 ENOG4105C5I Dehydrogenase B7O99_09075 ENOG4105CHR reductase B7O99_09080 ENOG4105CBN LysR family transcriptional regulator B7O99_09095 ENOG4105DBV ornithine carbamoyltransferase B7O99_09100 ENOG4105CDH Citrulline--aspartate ligase B7O99_09105 ENOG4105DFH Transport of potassium into the cell (By similarity) B7O99_09110 ENOG4105DHQ Histidine kinase B7O99_09115 ENOG4105XJC Two component transcriptional regulator (Winged helix family B7O99_09140 ENOG4105K70 DNA-binding protein B7O99_09145 ENOG4107E2E PKHD-type hydroxylase B7O99_09150 ENOG4105C28 cystathionine B7O99_09155 ENOG4105C2N RNA methyltransferase TrmH family group 3 B7O99_09160 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) B7O99_09180 ENOG41082BV acetyltransferase B7O99_09185 ENOG4105RK9 auxin efflux carrier B7O99_09195 ENOG4105CBC glutamate synthase B7O99_09200 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) B7O99_09210 ENOG41067HS methyltransferase B7O99_09245 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase B7O99_09250 ENOG4105BZU Histidine kinase B7O99_09285 ENOG4105T86 cytochrome C B7O99_09290 ENOG4107QTF adenylosuccinate lyase B7O99_09295 ENOG4108U78 Glutathione S-transferase B7O99_09310 ENOG4105ETT transcriptional Regulator, LysR family B7O99_09325 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) B7O99_09330 ENOG4105W8H transhydrogenase (subunit alpha B7O99_09335 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) B7O99_09345 ENOG4107RNH Outer membrane receptor FepA B7O99_09350 ENOG4105NIV Esterase B7O99_09355 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) B7O99_09365 ENOG4105CQB FAD linked oxidase domain protein B7O99_09370 ENOG4105CQB FAD linked oxidase domain protein B7O99_09375 ENOG4108QZZ filamentous hemagglutinin B7O99_09375 ENOG4108QZZ filamentous hemagglutinin B7O99_09380 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) B7O99_09385 ENOG4105D1U peptidase U62 modulator of DNA gyrase B7O99_09395 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS B7O99_09405 ENOG4105CD8 aminopeptidase N B7O99_09410 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 B7O99_09425 ENOG4105D6E homoserine dehydrogenase B7O99_09430 ENOG4105CHM Aminotransferase B7O99_09435 ENOG4108UIV Protein of unknown function (DUF498/DUF598) B7O99_09440 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen B7O99_09445 ENOG4108IAB Phoh family B7O99_09450 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) B7O99_09455 ENOG4105DHU Bile acid B7O99_09460 ENOG4105CDU Replicative dna helicase B7O99_09475 ENOG4105K9Q Binds to the 23S rRNA (By similarity) B7O99_09480 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) B7O99_09490 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) B7O99_09495 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) B7O99_09500 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) B7O99_09505 ENOG4105CTB Polyprenyl synthetase B7O99_09510 ENOG41082UU Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) B7O99_09560 ENOG4108KAZ Involved in phosphonate degradation (By similarity) B7O99_09570 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_09575 ENOG4105DUM transcriptional regulator, lysR family B7O99_09585 ENOG4105KHC sulfurtransferase B7O99_09595 ENOG4105D0M Protease HtpX homolog B7O99_09600 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein B7O99_09605 ENOG4106UX7 integral membrane protein B7O99_09615 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes B7O99_09635 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) B7O99_09645 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_09655 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component B7O99_09665 ENOG4108JPW Aminotransferase B7O99_09670 ENOG4105K8K Cupin 2, conserved barrel B7O99_09680 ENOG4105CE7 Amidase, hydantoinase carbamoylase family B7O99_09690 ENOG4105C26 Dehydrogenase B7O99_09700 ENOG4105C8Y Acetylornithine aminotransferase B7O99_09710 ENOG4105CDY transcriptional regulatory protein B7O99_09715 ENOG4105C12 Phosphoribosylglycinamide synthetase B7O99_09720 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) B7O99_09730 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) B7O99_09740 ENOG4108Z03 MAF-like protein B7O99_09745 ENOG4108P8G outer membrane autotransporter barrel B7O99_09780 ENOG4108MGI Transcriptional regulator B7O99_09785 ENOG4105C09 Bile acid B7O99_09790 ENOG4105CYC Transferase B7O99_09795 ENOG4105CMU LysR family (Transcriptional regulator B7O99_09800 ENOG4105EGS Mechanosensitive ion channel B7O99_09815 ENOG4105P69 integral membrane protein B7O99_09820 ENOG4108594 Permease of the drug metabolite transporter B7O99_09845 ENOG4107QIJ Aconitate hydratase 2 B7O99_09855 ENOG41090EK ompa motb domain protein B7O99_09875 ENOG4107QM5 aconitate hydratase B7O99_09880 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b B7O99_09895 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) B7O99_09900 ENOG4105XUA cytochrome c B7O99_09910 ENOG4105EMN RNA polymerase sigma factor B7O99_09995 ENOG4105BZU Histidine kinase B7O99_10015 ENOG4108JQ5 ABC transporter B7O99_10020 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component B7O99_10030 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein B7O99_10040 ENOG4105D7N magnesium and cobalt transport protein CorA B7O99_10060 ENOG4108JPW Aminotransferase B7O99_10065 ENOG4105C26 Dehydrogenase B7O99_10070 ENOG4105ECY inositol monophosphatase B7O99_10095 ENOG4105D7W serine acetyltransferase B7O99_10100 ENOG4107QP8 phosphohexose isomerase B7O99_10115 ENOG4105WH1 Two component transcriptional regulator luxr family B7O99_10125 ENOG4107QPN acyl-Coa dehydrogenase B7O99_10130 ENOG4105CHU acetyl-coa acetyltransferase B7O99_10150 ENOG4105CHU acetyl-coa acetyltransferase B7O99_10160 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_10185 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) B7O99_10190 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding B7O99_10195 ENOG4108UAU isochorismatase B7O99_10220 ENOG4108XHQ (2Fe-2S)-binding domain protein B7O99_10230 ENOG4108IV0 ABC, transporter B7O99_10235 ENOG4105C0Z ABC transporter B7O99_10250 ENOG4108VHT MarR family transcriptional regulator B7O99_10270 ENOG4107BJW polysaccharide deacetylase B7O99_10275 ENOG4105CND Glycosyl transferase, family 2 B7O99_10285 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7O99_10310 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) B7O99_10320 ENOG4105K4P CoA-binding domain protein B7O99_10325 ENOG4107HP6 Transcriptional regulator B7O99_10330 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7O99_10340 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_10350 ENOG4105F38 ABC transporter, permease B7O99_10365 ENOG4105RQF LysR family Transcriptional regulator B7O99_10375 ENOG41061TZ Short-chain dehydrogenase reductase Sdr B7O99_10385 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) B7O99_10390 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_10395 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_10400 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter B7O99_10425 ENOG4105CFH Aspartokinase B7O99_10435 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) B7O99_10445 ENOG4105C8N cysteinyl-tRNA synthetase B7O99_10450 ENOG4108PPB Seems to be required for the assembly of the photosystem I complex (By similarity) B7O99_10460 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) B7O99_10465 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) B7O99_10470 ENOG4105EE5 Membrane protein terC B7O99_10475 ENOG4105ECY inositol monophosphatase B7O99_10495 ENOG4105D64 Mechanosensitive ion channel B7O99_10530 ENOG4105WKW Pfam:DUF1458 B7O99_10540 ENOG4105EZE Cupin 4 family protein B7O99_10555 ENOG4105GJM (LipO)protein B7O99_10560 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7O99_10565 ENOG4108Z4T Peptidase M50 B7O99_10570 ENOG4107RTD sua5 ycio yrdc ywlc family protein B7O99_10575 ENOG4105CGZ zinc metallopeptidase B7O99_10615 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) B7O99_10620 ENOG41083UI stage II sporulation protein B7O99_10625 ENOG4105JGF anti-sigma regulatory factor serine threonine protein kinase B7O99_10630 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) B7O99_10815 ENOG4105EXG Transcriptional regulator B7O99_10860 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) B7O99_10865 ENOG4105CHR reductase B7O99_10870 ENOG4108IV0 ABC, transporter B7O99_10875 ENOG4105C0Z ABC transporter B7O99_10885 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_10910 ENOG4105CIF Ornithine Cyclodeaminase B7O99_10915 ENOG4105ERH Fumarylacetoacetate hydrolase B7O99_10930 ENOG4105EJC lysr family transcriptional regulator B7O99_10955 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_10965 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_10975 ENOG4105CD5 CoA-binding domain protein B7O99_10980 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit B7O99_10985 ENOG4107QX3 carboxylase B7O99_10990 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase B7O99_10995 ENOG4105FDP GntR family transcriptional regulator B7O99_11015 ENOG4107QSA Oxaloacetate decarboxylase B7O99_11030 ENOG4105DHT Metal Dependent Phosphohydrolase B7O99_11040 ENOG4105C26 Dehydrogenase B7O99_11050 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) B7O99_11070 ENOG4105FQ6 thiopurine methyltransferase B7O99_11075 ENOG4105BZ1 (ABC) transporter B7O99_11085 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) B7O99_11105 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_11115 ENOG4105C0Z ABC transporter B7O99_11120 ENOG4108IV0 ABC, transporter B7O99_11160 ENOG4107NQ8 LysR family Transcriptional regulator B7O99_11185 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_11225 ENOG4105CDA abc transporter atp-binding protein B7O99_11230 ENOG4105DRP amino acid AbC transporter B7O99_11235 ENOG4105EZ7 amino acid ABC transporter B7O99_11245 ENOG4105CH2 amidohydrolase B7O99_11250 ENOG4107RCH Diaminopropionate ammonia-lyase B7O99_11265 ENOG4105ERH Fumarylacetoacetate hydrolase B7O99_11275 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_11280 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter B7O99_11285 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_11305 ENOG4105CJP fad dependent oxidoreductase B7O99_11310 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7O99_11315 ENOG4108IV0 ABC, transporter B7O99_11320 ENOG4108IUZ ABC transporter B7O99_11325 ENOG4105CF8 branched-chain amino acid ABC transporter, permease B7O99_11330 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_11350 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) B7O99_11355 ENOG4105F95 Monooxygenase B7O99_11390 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_11400 ENOG4105C0Z ABC transporter B7O99_11405 ENOG4108IV0 ABC, transporter B7O99_11420 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_11425 ENOG4108IV0 ABC, transporter B7O99_11430 ENOG4105C0Z ABC transporter B7O99_11450 ENOG4105C0A alcohol dehydrogenase B7O99_11495 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) B7O99_11500 ENOG4105E2Z phosphate ABC transporter (Permease B7O99_11505 ENOG4105C8U phosphate abc transporter B7O99_11510 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) B7O99_11520 ENOG4105C9X ppx gppa phosphatase B7O99_11530 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) B7O99_11540 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) B7O99_11545 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) B7O99_11550 ENOG4105HBR Rna-binding protein B7O99_11560 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) B7O99_11565 ENOG4105C8Q Methyl-accepting chemotaxis B7O99_11570 ENOG4105C2W permease B7O99_11585 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_11595 ENOG4105CVJ phosphoglycerate mutase B7O99_11600 ENOG4105EMU Dehydrogenase B7O99_11615 ENOG4105F8V Hydrolase, tatD family B7O99_11620 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) B7O99_11635 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) B7O99_11645 ENOG410904N short-chain dehydrogenase reductase B7O99_11665 ENOG4108IQE Amp-dependent synthetase and ligase B7O99_11670 ENOG4108IV0 ABC, transporter B7O99_11680 ENOG4105CF8 branched-chain amino acid ABC transporter, permease B7O99_11690 ENOG4105C0Z ABC transporter B7O99_11695 ENOG4105CGU Enoyl-CoA hydratase B7O99_11705 ENOG4105WVQ Fe-S assembly protein IscX B7O99_11710 ENOG4108ZIT Ferredoxin, 2FE-2S B7O99_11725 ENOG4108Z4V iron-sulfur cluster assembly B7O99_11730 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins B7O99_11735 ENOG4105C3J Cysteine desulfurase B7O99_11740 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family B7O99_11755 ENOG4105CGF Aromatic amino acid aminotransferase B7O99_11765 ENOG4108P8G outer membrane autotransporter barrel B7O99_11775 ENOG4107QNJ CoA-transferase subunit B B7O99_11790 ENOG4105D2B acyl-CoA dehydrogenase B7O99_11795 ENOG4105CHR reductase B7O99_11800 ENOG4105CHU acetyl-coa acetyltransferase B7O99_11810 ENOG4108UKI Enoyl-CoA hydratase B7O99_11820 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_11825 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_11830 ENOG4105CN8 Transcriptional regulator B7O99_11835 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) B7O99_11840 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) B7O99_11845 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) B7O99_11855 ENOG4108TEB UPF0114 protein B7O99_11860 ENOG4105VEQ Cold shock protein B7O99_11870 ENOG4105VEQ Cold shock protein B7O99_11900 ENOG4105CHM Aminotransferase B7O99_11915 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) B7O99_11920 ENOG4105C5H ABC transporter B7O99_11925 ENOG4105PE1 Receptor B7O99_11930 ENOG4105C4R Atp-dependent dna helicase B7O99_11950 ENOG4108V3E phosphoribosylglycinamide formyltransferase B7O99_11955 ENOG4105DTN riboflavin biosynthesis protein ribF B7O99_11965 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) B7O99_11970 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase B7O99_12000 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) B7O99_12030 ENOG4105CIF Ornithine Cyclodeaminase B7O99_12035 ENOG4108Z9K Osmotically inducible protein B7O99_12045 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) B7O99_12050 ENOG41080Z8 PHOSPHOCARRIER protein B7O99_12060 ENOG4105D7Z glutathione synthase B7O99_12065 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) B7O99_12070 ENOG4105C22 threonyL-tRNA synthetase B7O99_12075 ENOG4108T94 DNA-binding transcriptional activator BglJ B7O99_12085 ENOG4105D4P Coproporphyrinogen iii oxidase B7O99_12095 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) B7O99_12135 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_12145 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_12150 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) B7O99_12160 ENOG4107QJH Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) B7O99_12165 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) B7O99_12170 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) B7O99_12175 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) B7O99_12185 ENOG4108JJB ABC transporter B7O99_12215 ENOG4105QAX Iron-sulfur B7O99_12220 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) B7O99_12255 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) B7O99_12260 ENOG4105CVM Molybdenum cofactor synthesis domain protein B7O99_12265 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b B7O99_12270 ENOG4105ERG peptidase m48, ste24p B7O99_12285 ENOG4105BZU Histidine kinase B7O99_12290 ENOG4106WF9 DNA-binding transcriptional regulator TorR B7O99_12295 ENOG4105CNG UPF0061 protein B7O99_12305 ENOG4107S2Z UPF0761 membrane protein B7O99_12315 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) B7O99_12390 ENOG4105MWK D-amino acid dehydrogenase, small subunit B7O99_12400 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) B7O99_12435 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) B7O99_12445 ENOG4108Z6K Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity) B7O99_12450 ENOG4108JPW Aminotransferase B7O99_12470 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) B7O99_12490 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7O99_12500 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7O99_12505 ENOG4105K63 Thioredoxin B7O99_12510 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) B7O99_12525 ENOG4105WPN DNA integration recombination invertion protein B7O99_12530 ENOG4105EJQ L-serine dehydratase B7O99_12535 ENOG4105EAM Na Pi-cotransporter B7O99_12540 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) B7O99_12550 ENOG4105C2M dna polymerase I B7O99_12555 ENOG4108URH decarboxylase B7O99_12590 ENOG4105CHV Transcription elongation factor NusA B7O99_12600 ENOG4105FE9 pseudouridine synthase B7O99_12605 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) B7O99_12615 ENOG4105EJC lysr family transcriptional regulator B7O99_12625 ENOG4105CKI cobalamin synthesis protein B7O99_12645 ENOG4108RXX maleylacetoacetate isomerase B7O99_12655 ENOG4108YZY peptidylprolyl cis-trans isomerase B7O99_12675 ENOG4105NRA 50s ribosomal protein l31 type b B7O99_12710 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) B7O99_12715 ENOG4105CP2 von willebrand factor, type a B7O99_12735 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) B7O99_12750 ENOG4105CVN desaturase B7O99_12750 ENOG4105CVN desaturase B7O99_12770 ENOG4105CJ1 ABC, transporter B7O99_12835 ENOG4108P8G outer membrane autotransporter barrel B7O99_12845 ENOG4105DS0 Transcriptional regulator, Crp Fnr family B7O99_12860 ENOG4108YZ4 nudix hydrolase B7O99_12865 ENOG4105VRT cytoplasmic protein B7O99_12875 ENOG4108KPJ rna polymerase sigma factor B7O99_12880 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) B7O99_12915 ENOG4105EAB amino acid AbC transporter B7O99_12920 ENOG4105EAD ABC transporter B7O99_12925 ENOG4105DRP amino acid AbC transporter B7O99_12950 ENOG4105Z2P Protein of unknown function (DUF465) B7O99_12955 ENOG4105D94 Major Facilitator Superfamily B7O99_12965 ENOG4105BZU Histidine kinase B7O99_12970 ENOG4105IPI Membrane B7O99_12975 ENOG4105E3A (ABC) transporter B7O99_12980 ENOG4105DA5 (ABC) transporter B7O99_13025 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i B7O99_13040 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) B7O99_13055 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) B7O99_13060 ENOG4105VAW lrga family B7O99_13065 ENOG41067MG lrgb family B7O99_13090 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase B7O99_13095 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) B7O99_13100 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) B7O99_13110 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) B7O99_13115 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7O99_13125 ENOG4105C1P efflux transporter, rnd family, mfp subunit B7O99_13145 ENOG4105F4R Transcriptional regulator mode B7O99_13150 ENOG4105D5T phosphonate abc transporter B7O99_13165 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) B7O99_13175 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_13180 ENOG4105E39 Enoyl-CoA hydratase B7O99_13190 ENOG4105DRR Transcriptional regulator, GntR family B7O99_13200 ENOG4105CHU acetyl-coa acetyltransferase B7O99_13210 ENOG4108IJ7 Glycine betaine B7O99_13215 ENOG4108HQS Glycine betaine B7O99_13225 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase B7O99_13230 ENOG4105C2C drug resistance transporter, Bcr CflA B7O99_13235 ENOG4105KDC 50s ribosomal protein l28 B7O99_13240 ENOG4105W0E 50S ribosomal protein L33 B7O99_13255 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes B7O99_13290 ENOG4105EUF amidase EC 3.5.1.4 B7O99_13295 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) B7O99_13335 ENOG4105C03 ribonuclease B7O99_13340 ENOG4105CQC Prephenate dehydratase B7O99_13355 ENOG4105BZ1 (ABC) transporter B7O99_13360 ENOG4105XA0 heptosyltransferase ii B7O99_13370 ENOG4105KRS Proteinase inhibitor B7O99_13385 ENOG4105DIJ Phosphoethanolamine transferase B7O99_13390 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) B7O99_13395 ENOG4106WTF Glycosyl transferase, family 2 B7O99_13400 ENOG4107BJW polysaccharide deacetylase B7O99_13405 ENOG4105CPK Glycosyl transferase (Group 1 B7O99_13410 ENOG4105C0B DNA polymerase III (alpha subunit) B7O99_13420 ENOG4105CQ7 ATP-dependent helicase B7O99_13425 ENOG4108EKC n-acetylglutamate synthase B7O99_13430 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) B7O99_13435 ENOG4105HSS phospholipase C B7O99_13440 ENOG4108UTW Plays a role in the regulation of phosphate uptake B7O99_13450 ENOG4105CSU acyl-Coa dehydrogenase B7O99_13465 ENOG4108RB4 3-methyladenine DNA glycosylase B7O99_13475 ENOG4105D38 putrescine abc transporter B7O99_13480 ENOG4105F38 ABC transporter, permease B7O99_13485 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7O99_13490 ENOG4107RUE extracellular solute-binding protein family 1 B7O99_13495 ENOG4108W7E Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity) B7O99_13505 ENOG4105CV6 ABC transporter, permease B7O99_13510 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_13520 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_13525 ENOG4105X0I Fimbrial B7O99_13530 ENOG4105X0I Fimbrial B7O99_13545 ENOG4108ZJI phenylacetic acid degradation protein B7O99_13550 ENOG4108UKI Enoyl-CoA hydratase B7O99_13560 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) B7O99_13565 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit B7O99_13570 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit B7O99_13575 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit B7O99_13580 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit B7O99_13595 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) B7O99_13600 ENOG4105D0M Protease HtpX homolog B7O99_13605 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) B7O99_13610 ENOG4105CPC Aldo Keto reductase B7O99_13615 ENOG4105P8F nudix hydrolase B7O99_13620 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) B7O99_13640 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) B7O99_13660 ENOG4105ECW sulfate abc transporter B7O99_13665 ENOG4108I5D sulfate abc transporter B7O99_13680 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) B7O99_13690 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_13695 ENOG4108S8N class II Aldolase B7O99_13720 ENOG4105Y49 secretion protein, HlyD family B7O99_13730 ENOG4106KED esterase YpfH B7O99_13755 ENOG4105KPV Transcriptional regulator B7O99_13760 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) B7O99_13770 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) B7O99_13790 ENOG4108JQC penicillin-binding protein 1A B7O99_13795 ENOG4108R1E Serine threonine protein phosphatase 1 B7O99_13810 ENOG4105CPC Aldo Keto reductase B7O99_13820 ENOG4108JJ7 ABC transporter B7O99_13855 ENOG4108P8G outer membrane autotransporter barrel B7O99_13860 ENOG4108P8G outer membrane autotransporter barrel B7O99_13875 ENOG4105BZU Histidine kinase B7O99_13880 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor B7O99_13885 ENOG4108M8H domain protein B7O99_13890 ENOG4108Z7R Chaperone CsaA B7O99_13915 ENOG4105DIA mandelate racemase muconate lactonizing B7O99_13920 ENOG4105DDW LysR family Transcriptional regulator B7O99_13925 ENOG4105CHR reductase B7O99_13930 ENOG4105C0R drug resistance transporter emrb qaca subfamily B7O99_13945 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A B7O99_13960 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase B7O99_13975 ENOG4105EE5 Membrane protein terC B7O99_13990 ENOG4108Q6X Aspartoacylase (EC 3.5.1.15) B7O99_14010 ENOG4105BZU Histidine kinase B7O99_14015 ENOG4108ZCF integral membrane protein B7O99_14025 ENOG4105EMN RNA polymerase sigma factor B7O99_14030 ENOG4105BZU Histidine kinase B7O99_14055 ENOG4105K78 MarR family Transcriptional regulator B7O99_14085 ENOG4105C7K acetolactate synthase B7O99_14090 ENOG4105CE7 Amidase, hydantoinase carbamoylase family B7O99_14095 ENOG4105C26 Dehydrogenase B7O99_14100 ENOG4105D82 Glutamate dehydrogenase B7O99_14110 ENOG4105CDA abc transporter atp-binding protein B7O99_14135 ENOG4105F8V Hydrolase, tatD family B7O99_14140 ENOG4105C6E dna polymerase iii B7O99_14145 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) B7O99_14150 ENOG4105HHA aminodeoxychorismate lyase B7O99_14155 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) B7O99_14170 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase B7O99_14175 ENOG4108IPT Naphthoate synthase B7O99_14180 ENOG4105C1G acyl-Coa dehydrogenase B7O99_14190 ENOG4108Z1B Cyclase dehydrase B7O99_14205 ENOG4107QX8 SPFH domain, Band 7 family protein B7O99_14220 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) B7O99_14225 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) B7O99_14235 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) B7O99_14240 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) B7O99_14260 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) B7O99_14265 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane B7O99_14270 ENOG4105DZP Membrane-associated zinc metalloprotease B7O99_14280 ENOG4105KNE Phosphatidate cytidylyltransferase B7O99_14285 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) B7O99_14290 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) B7O99_14305 ENOG4105CE9 30S ribosomal protein S2 B7O99_14310 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) B7O99_14330 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase B7O99_14345 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase B7O99_14355 ENOG4105DTS flagellar hook-associated B7O99_14360 ENOG4105MQ3 flagellar protein FliS B7O99_14375 ENOG4105D00 flagellar biosynthetic protein flhB B7O99_14385 ENOG4105VQ0 flagellar hook-basal body complex protein fliE B7O99_14395 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) B7O99_14400 ENOG4108CG0 Flagellar assembly protein B7O99_14405 ENOG4108JIR Flagellum-specific ATP synthase B7O99_14420 ENOG4107ZI8 flagellar basal body-associated protein flil B7O99_14425 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) B7O99_14440 ENOG4105CN7 Flagellar biosynthetic protein FliP B7O99_14445 ENOG4105VS8 Flagellar biosynthetic protein fliq B7O99_14460 ENOG4105C8Q Methyl-accepting chemotaxis B7O99_14465 ENOG4105DTJ flagellar hook-associated protein B7O99_14470 ENOG4105E1Q flagellar hook-associated protein B7O99_14475 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj B7O99_14480 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) B7O99_14495 ENOG4108KPB Flagellar basal-body rod protein FlgF B7O99_14500 ENOG4105BZE flagellar hook protein, FlgE B7O99_14505 ENOG4105W00 Flagellar hook capping protein B7O99_14510 ENOG4108ZC9 flagellar basal-body rod protein flgc B7O99_14515 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) B7O99_14525 ENOG4105M9M anti-sigma28 factor FlgM B7O99_14545 ENOG4105D00 flagellar biosynthetic protein flhB B7O99_14550 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) B7O99_14555 ENOG4108VYJ response regulator receiver protein B7O99_14565 ENOG4105BZU Histidine kinase B7O99_14570 ENOG4105C8Q Methyl-accepting chemotaxis B7O99_14575 ENOG4108V3W Chemotaxis protein, CheW B7O99_14580 ENOG4105CBS Chea signal transduction histidine kinase B7O99_14590 ENOG4105ER2 Ompa motb domain protein B7O99_14595 ENOG4107RD7 Flagellar Motor Protein, MotA B7O99_14600 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region B7O99_14605 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) B7O99_14615 ENOG4105I03 Flagellin B7O99_14620 ENOG4107QN2 dihydrolipoyl dehydrogenase B7O99_14625 ENOG4107QSN dihydrolipoamide acetyltransferase B7O99_14630 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) B7O99_14635 ENOG4105BZU Histidine kinase B7O99_14640 ENOG4108ZXC Two component transcriptional regulator, luxr family B7O99_14650 ENOG4105DGW oligopeptidase A B7O99_14665 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7O99_14670 ENOG4105BZS acriflavin resistance protein B7O99_14675 ENOG4105C1P efflux transporter, rnd family, mfp subunit B7O99_14680 ENOG4105JQN Transcriptional regulator B7O99_14685 ENOG4105FE9 pseudouridine synthase B7O99_14690 ENOG4105RUM Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity) B7O99_14700 ENOG4108VWS Yaeq family B7O99_14705 ENOG4105N14 lysine exporter protein LysE YggA B7O99_14715 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component B7O99_14720 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component B7O99_14725 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_14730 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) B7O99_14735 ENOG4105DUM transcriptional regulator, lysR family B7O99_14750 ENOG4105VEJ Heat shock protein B7O99_14760 ENOG4108YZA Nitrogen regulatory protein pii B7O99_14770 ENOG4105CUY Mechanosensitive ion channel B7O99_14775 ENOG4105CH7 arginosuccinase B7O99_14785 ENOG4105W1Y Transcriptional regulator B7O99_14800 ENOG4105E5Q amino acid AbC transporter B7O99_14805 ENOG4105CDA abc transporter atp-binding protein B7O99_14815 ENOG4105VIG Sec-independent protein translocase protein TatC B7O99_14875 ENOG4108UAU isochorismatase B7O99_14880 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_14890 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_14900 ENOG4105EZR dyp-type peroxidase family protein B7O99_14965 ENOG4105DDW LysR family Transcriptional regulator B7O99_14970 ENOG4105DXI Major Facilitator superfamily B7O99_14980 ENOG4108K0D peptidase, M48 B7O99_14985 ENOG4105CHR reductase B7O99_14990 ENOG4105CBN LysR family transcriptional regulator B7O99_15000 ENOG4105FDP GntR family transcriptional regulator B7O99_15015 ENOG4107Z6I Thiamine biosynthesis protein B7O99_15030 ENOG4105C01 Dihydroxy-acid dehydratase B7O99_15045 ENOG4105C01 Dihydroxy-acid dehydratase B7O99_15050 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase B7O99_15055 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) B7O99_15060 ENOG4105EXW epimerase dehydratase B7O99_15065 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_15075 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_15080 ENOG4107RSM transcriptional regulator B7O99_15085 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7O99_15140 ENOG4105CYM Glutathione S-transferase B7O99_15155 ENOG4105DC8 reductase B7O99_15160 ENOG4105N14 lysine exporter protein LysE YggA B7O99_15165 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) B7O99_15175 ENOG4105EXG Transcriptional regulator B7O99_15200 ENOG4105CF7 AraC family transcriptional regulator B7O99_15235 ENOG4105XYF acetyltransferase B7O99_15240 ENOG4105BZ1 (ABC) transporter B7O99_15265 ENOG4105CHH sulfate transporter B7O99_15300 ENOG4105KCV RNA signal recognition particle 4.5S RNA B7O99_15305 ENOG4107ZY0 Phenazine biosynthesis-like protein B7O99_15310 ENOG4105SKE transcriptional Regulator LysR family B7O99_15315 ENOG4106BRA Membrane B7O99_15330 ENOG4105C26 Dehydrogenase B7O99_15335 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family B7O99_15340 ENOG4105CV8 reductase B7O99_15365 ENOG4107QWP ABC-2 type transporter B7O99_15385 ENOG4105DRR Transcriptional regulator, GntR family B7O99_15390 ENOG4105II7 pyrroline-5-carboxylate reductase B7O99_15400 ENOG4105DG4 malate L-lactate dehydrogenase B7O99_15410 ENOG4108TZY GntR Family Transcriptional Regulator B7O99_15435 ENOG4108Z4X TRANSCRIPTIONal B7O99_15450 ENOG4105ETE Transcriptional regulator (LacI family B7O99_15455 ENOG4108JQ6 ABC transporter B7O99_15470 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_15520 ENOG4105C26 Dehydrogenase B7O99_15525 ENOG4108PGP mmge prpd family protein B7O99_15530 ENOG4105GAK amidohydrolase 2 B7O99_15545 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_15565 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_15575 ENOG4105CY0 Metallo-Beta-Lactamase B7O99_15590 ENOG4105CYM Glutathione S-transferase B7O99_15600 ENOG4107YPT transcriptional regulator B7O99_15630 ENOG4105ECI YeeC-like protein B7O99_15635 ENOG4105F6A helicase B7O99_15660 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) B7O99_15675 ENOG4105WH1 Two component transcriptional regulator luxr family B7O99_15680 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) B7O99_15695 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase B7O99_15700 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen B7O99_15740 ENOG4108QZZ filamentous hemagglutinin B7O99_15745 ENOG4108ETH Formylglycinamide ribotide synthetase B7O99_15750 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter B7O99_15755 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_15770 ENOG4105DB7 PHP domain protein B7O99_15795 ENOG4108YZN class I peptide chain release factor B7O99_15805 ENOG4105D3R alkyl hydroperoxide reductase B7O99_15810 ENOG4105CSU acyl-Coa dehydrogenase B7O99_15815 ENOG4105C10 Electron transfer flavoprotein B7O99_15820 ENOG4105BZJ Electron transfer flavoprotein B7O99_15830 ENOG4105CVE Lytic murein transglycosylase B7O99_15835 ENOG4105C6T cysteine synthase B7O99_15845 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) B7O99_15850 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) B7O99_15855 ENOG4105CFV Tetratricopeptide repeat protein B7O99_15870 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) B7O99_15885 ENOG4105EVN Prephenate dehydrogenase B7O99_15895 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) B7O99_15900 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7O99_15905 ENOG4105UYK outer membrane protein a B7O99_15915 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) B7O99_15920 ENOG4105F27 Major Facilitator B7O99_15955 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_15990 ENOG4105DDW LysR family Transcriptional regulator B7O99_16005 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase B7O99_16025 ENOG41079YP Citrate utilization protein b B7O99_16030 ENOG4107EFR Flavocytochrome c B7O99_16035 ENOG4105C26 Dehydrogenase B7O99_16040 ENOG4105DXD 2-methylcitrate dehydratase B7O99_16050 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component B7O99_16075 ENOG4105DTI Phosphonopyruvate decarboxylase B7O99_16080 ENOG4105CHM Aminotransferase B7O99_16100 ENOG4108DBC nitroreductase B7O99_16105 ENOG4105C0R drug resistance transporter emrb qaca subfamily B7O99_16110 ENOG4105BZU Histidine kinase B7O99_16125 ENOG4105CVE Lytic murein transglycosylase B7O99_16130 ENOG4105ED9 Protein of unknown function (DUF455) B7O99_16145 ENOG4105BZ1 (ABC) transporter B7O99_16155 ENOG4105D9M gamma-glutamylcysteine synthetase B7O99_16160 ENOG4105VDW Csbd family B7O99_16170 ENOG4105K3G Periplasmic Protein B7O99_16180 ENOG4105JAB phenazine biosynthesis protein, phzf family B7O99_16205 ENOG4108NVM synthesis repressor PhaR B7O99_16210 ENOG4105CHR reductase B7O99_16215 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class B7O99_16220 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase B7O99_16225 ENOG4105C34 Pseudouridine synthase B7O99_16235 ENOG4105DVT helicase B7O99_16240 ENOG4105BZM domain protein B7O99_16245 ENOG4105C31 Tryptophanyl-tRNA synthetase B7O99_16265 ENOG4105E0K tonB-dependent siderophore receptor B7O99_16275 ENOG4108SF5 RNA Polymerase B7O99_16280 ENOG4105E2B Taurine dioxygenase B7O99_16285 ENOG4105CHR reductase B7O99_16295 ENOG4107RSM transcriptional regulator B7O99_16300 ENOG4105CHR reductase B7O99_16305 ENOG4105D6Z AFG1 family ATPase B7O99_16310 ENOG4107QN2 dihydrolipoyl dehydrogenase B7O99_16315 ENOG4105C7S Dehydrogenase B7O99_16320 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 B7O99_16330 ENOG4108YXU transcriptional regulator AsnC family B7O99_16335 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) B7O99_16340 ENOG4105C6K Malic enzyme B7O99_16345 ENOG4105X0I Fimbrial B7O99_16360 ENOG4105BZN citrate synthase B7O99_16365 ENOG41060IS Flavinator of succinate dehydrogenase B7O99_16370 ENOG4105E33 succinate dehydrogenase B7O99_16380 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein B7O99_16385 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit B7O99_16390 ENOG4105FDP GntR family transcriptional regulator B7O99_16395 ENOG4105D9Z Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) B7O99_16400 ENOG4105CR4 methylisocitrate lyase B7O99_16405 ENOG4105BZN citrate synthase B7O99_16410 ENOG4108I0Z Aconitate hydratase B7O99_16415 ENOG4105C7F AcnD-accessory protein PrpF B7O99_16420 ENOG4105DXD 2-methylcitrate dehydratase B7O99_16425 ENOG4108YXA Membrane B7O99_16450 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) B7O99_16460 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) B7O99_16495 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) B7O99_16510 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) B7O99_16530 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component B7O99_16540 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_16545 ENOG4108JQ6 ABC transporter B7O99_16550 ENOG4105D44 asparaginase B7O99_16575 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase B7O99_16580 ENOG4105CMR udp-glucose 4-epimerase B7O99_16595 ENOG4105C5W Aldolase B7O99_16600 ENOG4108Q5Y Membrane B7O99_16605 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) B7O99_16615 ENOG4108ZJF Glcg protein B7O99_16620 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) B7O99_16625 ENOG4105K4H Nlp p60 protein B7O99_16635 ENOG4107R11 Transcriptional regulator B7O99_16640 ENOG4105C26 Dehydrogenase B7O99_16650 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family B7O99_16665 ENOG4105MYG DNA polymerase iii, chi subunit B7O99_16675 ENOG4108MN8 Membrane B7O99_16700 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) B7O99_16705 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) B7O99_16710 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) B7O99_16715 ENOG4105C3F Signal peptidase i B7O99_16720 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) B7O99_16725 ENOG4105C0H protease B7O99_16740 ENOG4105EMN RNA polymerase sigma factor B7O99_16750 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) B7O99_16760 ENOG4105CHR reductase B7O99_16765 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase B7O99_16775 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) B7O99_16780 ENOG4105VGS 50s ribosomal protein l32 B7O99_16785 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein B7O99_16790 ENOG4108UHJ MAF-like protein B7O99_16795 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) B7O99_16800 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase B7O99_16805 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) B7O99_16810 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) B7O99_16815 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) B7O99_16820 ENOG4105EI2 Pseudouridine synthase B7O99_16825 ENOG4105C03 ribonuclease B7O99_16835 ENOG41061N2 exported protein B7O99_16850 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) B7O99_16865 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) B7O99_16875 ENOG4105M4H endoribonuclease L-psp B7O99_16885 ENOG4108Z4U Ferredoxin B7O99_16890 ENOG4105DP0 ferredoxin-NADP reductase B7O99_16900 ENOG4108R3D Electron transport complex B7O99_16905 ENOG4105CSM endonuclease III B7O99_16910 ENOG4105C0Z ABC transporter B7O99_16915 ENOG4108IV0 ABC, transporter B7O99_16925 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_16940 ENOG4105CM2 brancheD-chain amino acid aminotransferase B7O99_16945 ENOG4108IV0 ABC, transporter B7O99_16950 ENOG4105C0Z ABC transporter B7O99_16965 ENOG4107ZYJ bioY protein B7O99_16970 ENOG4107QCX Transporter B7O99_16975 ENOG4108JJB ABC transporter B7O99_16980 ENOG4105E0X reductase B7O99_16990 ENOG4105M85 Bola protein B7O99_17010 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) B7O99_17015 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) B7O99_17020 ENOG4108UN4 phage SPO1 DNA polymerase-related protein B7O99_17025 ENOG41072GX Peptidase M22 Glycoprotease B7O99_17030 ENOG4105DPZ Two component transcriptional regulator (Winged helix family B7O99_17035 ENOG4105E0F Histidine kinase B7O99_17040 ENOG4105D3R alkyl hydroperoxide reductase B7O99_17045 ENOG4108X7C Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) B7O99_17070 ENOG4108JA2 transcriptioN-repair coupling factor B7O99_17075 ENOG4105EAC phosphoserine phosphatase B7O99_17080 ENOG4105F04 LysR family Transcriptional regulator B7O99_17090 ENOG4105C7K acetolactate synthase B7O99_17095 ENOG4105CHR reductase B7O99_17115 ENOG4108ESX Receptor B7O99_17125 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) B7O99_17130 ENOG4105C8S subunit m B7O99_17140 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) B7O99_17145 ENOG4105DF2 NADH dehydrogenase subunit j B7O99_17150 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) B7O99_17155 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) B7O99_17160 ENOG4108IEH NADH dehydrogenase subunit g B7O99_17175 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) B7O99_17185 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) B7O99_17190 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain B7O99_17195 ENOG4108Z9W Outer membrane porin B7O99_17215 ENOG410841Q phosphoesterase PA-phosphatase related protein B7O99_17225 ENOG4105CBD Diacylglycerol kinase B7O99_17230 ENOG4105DUM transcriptional regulator, lysR family B7O99_17235 ENOG4105C94 Transporter B7O99_17240 ENOG4105KVH Transcriptional regulator B7O99_17245 ENOG4105ENT Efflux transporter rnd family, mfp subunit B7O99_17255 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7O99_17265 ENOG41090JD Blue (Type 1) copper domain protein B7O99_17285 ENOG4105CJP fad dependent oxidoreductase B7O99_17305 ENOG4105E5N succinylglutamate desuccinylase aspartoacylase B7O99_17310 ENOG4105C28 cystathionine B7O99_17315 ENOG4107NQ8 LysR family Transcriptional regulator B7O99_17320 ENOG4107EXU Short-chain dehydrogenase reductase Sdr B7O99_17330 ENOG4105CH7 arginosuccinase B7O99_17345 ENOG4105DV9 Methylaspartate ammonia-lyase B7O99_17355 ENOG4105C94 Transporter B7O99_17370 ENOG4105CP7 Triose-phosphate isomerase B7O99_17390 ENOG4105C7B Threonine dehydratase B7O99_17405 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) B7O99_17420 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase B7O99_17425 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase B7O99_17430 ENOG4108ZP8 Acetolactate synthase small subunit B7O99_17435 ENOG4105C7K acetolactate synthase B7O99_17450 ENOG4105D1Q UPF0246 protein B7O99_17455 ENOG4105DTD Dehydrogenase B7O99_17460 ENOG4105CKD glutathione-regulated potassium-efflux system protein B7O99_17500 ENOG4108RWP Major Facilitator Superfamily protein B7O99_17505 ENOG4105CNM Receptor B7O99_17520 ENOG4105BZU Histidine kinase B7O99_17550 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) B7O99_17555 ENOG4105D1H recombination factor protein RarA B7O99_17565 ENOG4105CNU cell division protein FtsK B7O99_17570 ENOG4105C3M thioredoxin reductase B7O99_17575 ENOG4105C98 muts2 protein B7O99_17585 ENOG4107QN1 sodium solute B7O99_17605 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) B7O99_17610 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) B7O99_17615 ENOG4105C08 Histidine kinase B7O99_17620 ENOG4105EEX Two component transcriptional regulator (Winged helix family B7O99_17655 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) B7O99_17695 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ B7O99_17710 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) B7O99_17715 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) B7O99_17720 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) B7O99_17730 ENOG41090R7 Ferric uptake B7O99_17735 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) B7O99_17740 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) B7O99_17780 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) B7O99_17785 ENOG4105WIU sarcosine oxidase delta subunit B7O99_17790 ENOG4105DDR sarcosine oxidase (Beta subunit) B7O99_17800 ENOG4108M0I Transcriptional regulator B7O99_17805 ENOG4105DG4 malate L-lactate dehydrogenase B7O99_17815 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_17820 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_17825 ENOG4105DJG MaoC domain protein dehydratase B7O99_17835 ENOG4105CGU Enoyl-CoA hydratase B7O99_17860 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit B7O99_17870 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_17885 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase B7O99_17900 ENOG4105CJP fad dependent oxidoreductase B7O99_17910 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) B7O99_17920 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein B7O99_17925 ENOG410829K Lysine exporter protein (Lyse ygga) B7O99_17955 ENOG4105CC0 LysR family Transcriptional regulator B7O99_17995 ENOG41069M3 Transcriptional regulator B7O99_18000 ENOG4107TH8 cina domain protein B7O99_18015 ENOG4105C1J atp-dependent rna helicase B7O99_18030 ENOG4105CM2 brancheD-chain amino acid aminotransferase B7O99_18045 ENOG4105DNZ Alpha Beta Hydrolase B7O99_18050 ENOG4105ERG peptidase m48, ste24p B7O99_18065 ENOG4108Z9W Outer membrane porin B7O99_18080 ENOG4107RAQ aminopeptidase B7O99_18090 ENOG4105D0A hydroxylase B7O99_18095 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) B7O99_18135 ENOG4105C9U ATP-dependent DNA helicase RecQ B7O99_18145 ENOG4105DPZ Two component transcriptional regulator (Winged helix family B7O99_18160 ENOG4105C4M (Ubiquinol oxidase) subunit I B7O99_18175 ENOG4107QMS site-determining protein B7O99_18180 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) B7O99_18195 ENOG4105C5H ABC transporter B7O99_18220 ENOG4108JQ7 (ABC) transporter B7O99_18225 ENOG4105C3U ABC transporter B7O99_18230 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component B7O99_18245 ENOG4108SHN Glycosyl transferase, family 2 B7O99_18260 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) B7O99_18285 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_18290 ENOG4105FDP GntR family transcriptional regulator B7O99_18295 ENOG4105CUZ uba thif-type nad fad binding protein B7O99_18310 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) B7O99_18330 ENOG4107RSM transcriptional regulator B7O99_18335 ENOG4105CSU acyl-Coa dehydrogenase B7O99_18345 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_18350 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) B7O99_18370 ENOG4105C9Q fumarate hydratase class II B7O99_18375 ENOG4105K8N protein family UPF0079, ATPase B7O99_18380 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase B7O99_18385 ENOG4105DQR SNARE associated Golgi B7O99_18405 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) B7O99_18415 ENOG4105DJ0 Poly(A) Polymerase B7O99_18420 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase B7O99_18435 ENOG4105CG6 trap dicarboxylate transporter dctm subunit B7O99_18440 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_18445 ENOG4105FDP GntR family transcriptional regulator B7O99_18455 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase B7O99_18460 ENOG4107XDQ Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) B7O99_18475 ENOG4108R85 Short chain dehydrogenase B7O99_18485 ENOG4108MGF sugar kinase B7O99_18490 ENOG4105CI0 Citrate lyase B7O99_18500 ENOG4108M9J MaoC like domain protein B7O99_18520 ENOG4105FDP GntR family transcriptional regulator B7O99_18525 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) B7O99_18530 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) B7O99_18545 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit B7O99_18550 ENOG4105C38 Glycyl-tRNA synthetase beta subunit B7O99_18555 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase B7O99_18560 ENOG4105E9Q Acyl-transferase B7O99_18575 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) B7O99_18580 ENOG4107QPN acyl-Coa dehydrogenase B7O99_18590 ENOG4105CA9 Pyruvate kinase B7O99_18605 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) B7O99_18615 ENOG4105EHM Aminoglycoside phosphotransferase B7O99_18620 ENOG4108S0S Nucleotidyl transferase B7O99_18630 ENOG4105KZX Pterin carbinolamine dehydratase B7O99_18650 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) B7O99_18655 ENOG4105EUF amidase EC 3.5.1.4 B7O99_18690 ENOG4105D3D Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity) B7O99_18705 ENOG4108S3W Anti-feci sigma factor, fecr B7O99_18710 ENOG4105E0K tonB-dependent siderophore receptor B7O99_18715 ENOG4108YYC ycei family B7O99_18720 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) B7O99_18735 ENOG4105ETT transcriptional Regulator, LysR family B7O99_18760 ENOG4105ERH Fumarylacetoacetate hydrolase B7O99_18795 ENOG4105F6U Short-chain dehydrogenase reductase Sdr B7O99_18800 ENOG4108XFH Transcriptional regulator B7O99_18805 ENOG41066T0 asmA family B7O99_18810 ENOG4108R3E Dna-3-methyladenine glycosylase i B7O99_18815 ENOG4108Z4X TRANSCRIPTIONal B7O99_18830 ENOG4105WEM extracellular solute-binding protein B7O99_18835 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) B7O99_18840 ENOG4108IJ9 (ABC) transporter B7O99_18845 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component B7O99_18870 ENOG41073TP transcriptional regulator B7O99_18890 ENOG4105C0A alcohol dehydrogenase B7O99_18900 ENOG4105D01 (LipO)protein B7O99_18905 ENOG4108UMI ABC transporter, permease B7O99_18910 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) B7O99_18915 ENOG4105CJQ hydrolase, family 31 B7O99_18925 ENOG4105ECY inositol monophosphatase B7O99_18930 ENOG4105CEY Amp-dependent synthetase and ligase B7O99_18935 ENOG4105CH2 amidohydrolase B7O99_18940 ENOG4105DUM transcriptional regulator, lysR family B7O99_18945 ENOG4105HMI Membrane B7O99_18950 ENOG4105NAU thioesterase Superfamily protein B7O99_18955 ENOG4105CJW magnesium transporter B7O99_18970 ENOG4108XM1 transcriptional regulator AsnC family B7O99_18975 ENOG4105MWK D-amino acid dehydrogenase, small subunit B7O99_18980 ENOG4105CHR reductase B7O99_19005 ENOG4105DR5 peptidase B7O99_19015 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) B7O99_19020 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) B7O99_19025 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) B7O99_19030 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) B7O99_19040 ENOG4105DFU Cell wall formation (By similarity) B7O99_19060 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) B7O99_19065 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) B7O99_19070 ENOG4105CJN penicillin-binding protein B7O99_19075 ENOG4105N8N Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) B7O99_19080 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) B7O99_19085 ENOG4108V6E Cell division protein mraZ B7O99_19095 ENOG4105C5H ABC transporter B7O99_19100 ENOG4105EKE dihydroorotase B7O99_19105 ENOG4105CH2 amidohydrolase B7O99_19145 ENOG4105EW9 transcriptional regulator AsnC family B7O99_19150 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase B7O99_19155 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) B7O99_19160 ENOG4105W2Z cytochrome C, class I B7O99_19210 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) B7O99_19215 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase B7O99_19225 ENOG4105EXG Transcriptional regulator B7O99_19260 ENOG4107YD3 Thioesterase B7O99_19265 ENOG4105E02 MotA TolQ exbB proton channel B7O99_19270 ENOG4105M8F Biopolymer transport protein exbD tolR B7O99_19285 ENOG4105KCK Peptidoglycan-associated lipoprotein B7O99_19295 ENOG4105EHG Permease protein B7O99_19315 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes B7O99_19320 ENOG4108DN8 FAD dependent oxidoreductase B7O99_19335 ENOG4105JN3 extra-cytoplasmic solute receptor family protein B7O99_19345 ENOG4105CHU acetyl-coa acetyltransferase B7O99_19355 ENOG4105CC9 acyl-Coa dehydrogenase B7O99_19360 ENOG4106NZI LysR family Transcriptional regulator B7O99_19370 ENOG4105E39 Enoyl-CoA hydratase B7O99_19380 ENOG4105EE5 Membrane protein terC B7O99_19385 ENOG4108302 MgtC SapB transporter B7O99_19410 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7O99_19415 ENOG4105T38 integral membrane protein B7O99_19425 ENOG4107XM9 (LipO)protein B7O99_19460 ENOG4105D6U Sodium Glutamate Symporter B7O99_19470 ENOG4105CRW Short chain fatty acid transporter B7O99_19485 ENOG4107RZZ dna polymerase iii epsilon subunit B7O99_19490 ENOG4105BZS acriflavin resistance protein B7O99_19500 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) B7O99_19505 ENOG4105D1A Methyltransferase B7O99_19510 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) B7O99_19515 ENOG4105E9H Lytic Murein transglycosylase B7O99_19520 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH B7O99_19530 ENOG4108Q2J Inner membrane protein YebE B7O99_19540 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase B7O99_19565 ENOG4105CBG Sulfatase B7O99_19590 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) B7O99_19595 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) B7O99_19610 ENOG4105KI2 Urea amidohydrolase subunit beta B7O99_19620 ENOG4108YZ9 Urea amidohydrolase subunit gamma B7O99_19625 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) B7O99_19635 ENOG4108ZIT Ferredoxin, 2FE-2S B7O99_19650 ENOG4108TZY GntR Family Transcriptional Regulator B7O99_19655 ENOG4105DV9 Methylaspartate ammonia-lyase B7O99_19675 ENOG4105ED1 spovr family B7O99_19680 ENOG4106AKX UPF0229 protein B7O99_19685 ENOG4105CYN Serine protein kinase B7O99_19690 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) B7O99_19705 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) B7O99_19730 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) B7O99_19735 ENOG4108YX9 iron--sulfur cluster insertion protein erpA B7O99_19745 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase B7O99_19755 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) B7O99_19760 ENOG4105CH5 extracellular solute-binding protein, family 7 B7O99_19765 ENOG4105CMS peptidase U62, modulator of DNA gyrase B7O99_19790 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component B7O99_19795 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) B7O99_19800 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase B7O99_19805 ENOG4105C1J atp-dependent rna helicase B7O99_19815 ENOG4105DRR Transcriptional regulator, GntR family B7O99_19820 ENOG4105CD5 CoA-binding domain protein B7O99_19840 ENOG4108YXU transcriptional regulator AsnC family B7O99_19850 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) B7O99_19855 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) B7O99_19870 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) B7O99_19875 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein B7O99_19915 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase B7O99_19920 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein B7O99_19925 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) B7O99_19930 ENOG4107QX9 Thiol disulfide interChange protein B7O99_19935 ENOG4105DFU Cell wall formation (By similarity) B7O99_19940 ENOG4105IPS esterase B7O99_19960 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase B7O99_19970 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) B7O99_19975 ENOG4108Z20 Acyl-transferase B7O99_19980 ENOG4105CD3 dihydroorotase B7O99_19990 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) B7O99_19995 ENOG4108UJU UPF0301 protein B7O99_20000 ENOG4105VCQ rubredoxin B7O99_20040 ENOG4105C1G acyl-Coa dehydrogenase B7O99_20050 ENOG4105DTD Dehydrogenase B7O99_20060 ENOG4108IV0 ABC, transporter B7O99_20065 ENOG4105C0Z ABC transporter B7O99_20070 ENOG4105CF8 branched-chain amino acid ABC transporter, permease B7O99_20100 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) B7O99_20115 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7O99_20120 ENOG4105BZS acriflavin resistance protein B7O99_20135 ENOG4105DHA Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity) B7O99_20140 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) B7O99_20160 ENOG4107R03 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) B7O99_20165 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) B7O99_20180 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) B7O99_20195 ENOG4105CDA abc transporter atp-binding protein B7O99_20200 ENOG4105DRP amino acid AbC transporter B7O99_20205 ENOG4105EZ7 amino acid ABC transporter B7O99_20210 ENOG4107QXX ABC transporter B7O99_20215 ENOG4105CAK Cell division ATP-binding protein ftsE B7O99_20220 ENOG4105CRP Part of the ABC transporter FtsEX involved in B7O99_20235 ENOG4105CEN a g-specific adenine glycosylase B7O99_20250 ENOG4105C3R Methionine synthase B7O99_20255 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) B7O99_20260 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) B7O99_20275 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) B7O99_20280 ENOG4105DFG type I secretion outer membrane protein B7O99_20285 ENOG4107Z67 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) B7O99_20295 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) B7O99_20310 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) B7O99_20315 ENOG4105CK6 Two component transcriptional regulator (Winged helix family B7O99_20320 ENOG4105BZU Histidine kinase B7O99_20330 ENOG4105GR3 Histidine kinase B7O99_20340 ENOG4108JQ1 Dehydrogenase B7O99_20345 ENOG4108M0I Transcriptional regulator B7O99_20355 ENOG4105P4J Allophanate hydrolase, subunit 1 B7O99_20365 ENOG4105E7W lamb ycsf family protein B7O99_20400 ENOG4105DRR Transcriptional regulator, GntR family B7O99_20410 ENOG4105W39 Membrane B7O99_20415 ENOG4105C7B Threonine dehydratase B7O99_20420 ENOG4108Z9W Outer membrane porin B7O99_20430 ENOG4105EXG Transcriptional regulator B7O99_20435 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) B7O99_20440 ENOG4108JJ8 (ABC) transporter B7O99_20445 ENOG4108JJ9 ABC, transporter B7O99_20455 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii B7O99_20460 ENOG4105C4M (Ubiquinol oxidase) subunit I B7O99_20475 ENOG4105C2X Arabinose 5-phosphate isomerase B7O99_20495 ENOG4108IUZ ABC transporter B7O99_20500 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA B7O99_20505 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN B7O99_20510 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) B7O99_20515 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding B7O99_20535 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) B7O99_20550 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) B7O99_20555 ENOG4105W4M Transport-associated protein B7O99_20565 ENOG4105D01 (LipO)protein B7O99_20585 ENOG4107QPK )-transporter B7O99_20590 ENOG4105DG4 malate L-lactate dehydrogenase B7O99_20595 ENOG4105CNI cell division protein FtsW B7O99_20600 ENOG4105CJN penicillin-binding protein B7O99_20610 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) B7O99_20615 ENOG4105DFF Rod shape-determining protein mreb B7O99_20640 ENOG4105CGK Exodeoxyribonuclease III B7O99_20650 ENOG4105EN6 Membrane B7O99_20660 ENOG4105EJC lysr family transcriptional regulator B7O99_20665 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) B7O99_20690 ENOG4107YNJ LysR family Transcriptional regulator B7O99_20695 ENOG4105K6H D-cysteine desulfhydrase B7O99_20700 ENOG4107RP9 extracellular solute-binding protein, family 3 B7O99_20705 ENOG4105EAD ABC transporter B7O99_20710 ENOG4105DRP amino acid AbC transporter B7O99_20715 ENOG4105CDA abc transporter atp-binding protein B7O99_20725 ENOG4108Z9W Outer membrane porin B7O99_20730 ENOG4105EYM Major Facilitator superfamily B7O99_20735 ENOG4105DWV Homoserine O-trans-acetylase B7O99_20745 ENOG4105DG4 malate L-lactate dehydrogenase B7O99_20790 ENOG4105DND Transcriptional regulator B7O99_20795 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) B7O99_20800 ENOG4108Z9W Outer membrane porin B7O99_20810 ENOG4105C32 Amino acid ABC transporter (Permease) B7O99_20820 ENOG4105C0Z ABC transporter B7O99_20825 ENOG4108IV0 ABC, transporter B7O99_20835 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7O99_20845 ENOG41069M3 Transcriptional regulator B7O99_20855 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7O99_20865 ENOG4105E3B Multicopper oxidase B7O99_20910 ENOG4105E39 Enoyl-CoA hydratase B7O99_20915 ENOG41060WC Enoyl-CoA hydratase B7O99_20920 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) B7O99_20930 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_20940 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component B7O99_20945 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component B7O99_20950 ENOG4105C3U ABC transporter B7O99_20955 ENOG4108JQ7 (ABC) transporter B7O99_20965 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) B7O99_20970 ENOG4105C4R Atp-dependent dna helicase B7O99_20975 ENOG4105C25 Primosomal protein n' B7O99_20990 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) B7O99_20995 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) B7O99_21005 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) B7O99_21010 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) B7O99_21015 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) B7O99_21020 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) B7O99_21025 ENOG4107RAZ it plays a direct role in the translocation of protons across the membrane (By similarity) B7O99_21040 ENOG4105E39 Enoyl-CoA hydratase B7O99_21070 ENOG4105T95 Thiol disulfide interChange protein B7O99_21075 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family B7O99_21080 ENOG4105CA3 membrane-bound lytic murein transglycosylase B7O99_21085 ENOG4105NWN ApaG protein B7O99_21095 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) B7O99_21105 ENOG4105DDQ anthranilate synthase B7O99_21110 ENOG4107QYG anthranilate phosphoribosyltransferase B7O99_21115 ENOG4105DK0 Indole-3-glycerol phosphate synthase B7O99_21120 ENOG4105CYX Short-chain dehydrogenase reductase Sdr B7O99_21140 ENOG4105C8F Beta-lactamase domain protein B7O99_21205 ENOG4105DRR Transcriptional regulator, GntR family B7O99_21210 ENOG4105CIF Ornithine Cyclodeaminase B7O99_21235 ENOG4108SF5 RNA Polymerase B7O99_21250 ENOG4106QJH hemin transport protein B7O99_21255 ENOG4107R4I Periplasmic binding protein B7O99_21260 ENOG4105EHG Permease protein B7O99_21270 ENOG4105EWC Purine nucleoside phosphorylase B7O99_21280 ENOG4105CF1 Alkylated DNA repair protein B7O99_21285 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) B7O99_21290 ENOG4105BZU Histidine kinase B7O99_21300 ENOG4108NST exported protein B7O99_21305 ENOG4105DDW LysR family Transcriptional regulator B7O99_21315 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) B7O99_21325 ENOG4105C5R Aminotransferase B7O99_21330 ENOG4105DRR Transcriptional regulator, GntR family B7O99_21340 ENOG4105BZ9 Cytochrome C oxidase, subunit I B7O99_21360 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_21385 ENOG4105DDW LysR family Transcriptional regulator B7O99_21390 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) B7O99_21400 ENOG4105CHU acetyl-coa acetyltransferase B7O99_21420 ENOG4105CD5 CoA-binding domain protein B7O99_21455 ENOG4105C6Y Udp-glucose 6-dehydrogenase B7O99_21460 ENOG4105C0R drug resistance transporter emrb qaca subfamily B7O99_21465 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) B7O99_21490 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) B7O99_21515 ENOG4107QS1 Cytochrome C Oxidase, Subunit III B7O99_21530 ENOG4105BZ9 Cytochrome C oxidase, subunit I B7O99_21535 ENOG4105CV4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity) B7O99_21550 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) B7O99_21560 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) B7O99_21570 ENOG4105C4W S-formylglutathione hydrolase B7O99_21575 ENOG4107QPD alcohol dehydrogenase B7O99_21595 ENOG4105EIF outer membrane protein W B7O99_21605 ENOG4105DHJ ABC, transporter B7O99_21610 ENOG4105CY3 ABC transporter, permease B7O99_21615 ENOG4107PE3 Mammalian cell entry related domain protein B7O99_21630 ENOG4105DA5 (ABC) transporter B7O99_21635 ENOG4105E3A (ABC) transporter B7O99_21650 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) B7O99_21655 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) B7O99_21665 ENOG4105ECC imidazole-glycerol-phosphate dehydratase B7O99_21670 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) B7O99_21675 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase B7O99_21685 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase B7O99_21695 ENOG4107YU2 histidine triad (hIT) protein B7O99_21700 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) B7O99_21725 ENOG4107QNR UPF0135 protein B7O99_21735 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) B7O99_21740 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) B7O99_21745 ENOG4105EIX cytochrome c1 B7O99_21750 ENOG4107MKT Stringent starvation protein a B7O99_21755 ENOG4105KB2 stringent starvation protein b B7O99_21775 ENOG4105ENX hydrolase B7O99_21785 ENOG4106NZI LysR family Transcriptional regulator B7O99_21790 ENOG4105C3M thioredoxin reductase B7O99_21810 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7O99_21895 ENOG4108PCE TRANSFER protein B7O99_21915 ENOG4108Q5Y Membrane B7O99_21935 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) B7O99_21940 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_21945 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component B7O99_21950 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component B7O99_21960 ENOG4105HA9 of methanol dehydrogenase type B7O99_21970 ENOG4105C1J atp-dependent rna helicase B7O99_21975 ENOG410829K Lysine exporter protein (Lyse ygga) B7O99_21990 ENOG4108UQY Iron-storage protein B7O99_22010 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) B7O99_22020 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) B7O99_22025 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7O99_22030 ENOG4105ETE Transcriptional regulator (LacI family B7O99_22045 ENOG4105E0C molybdate abc transporter B7O99_22050 ENOG4108IJ6 ABC transporter B7O99_22055 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) B7O99_22060 ENOG4108IJ9 (ABC) transporter B7O99_22065 ENOG4105BZ7 extracellular solute-binding protein family 1 B7O99_22070 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component B7O99_22075 ENOG4105DRS transport system, permease B7O99_22100 ENOG4108Z33 Thiol disulfide Interchange Protein B7O99_22110 ENOG410829K Lysine exporter protein (Lyse ygga) B7O99_22125 ENOG4105C1G acyl-Coa dehydrogenase B7O99_22135 ENOG4105CHU acetyl-coa acetyltransferase B7O99_22140 ENOG4107QX3 carboxylase B7O99_22185 ENOG4108RPN Protein smg homolog B7O99_22200 ENOG4105C9U ATP-dependent DNA helicase RecQ B7O99_22215 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component B7O99_22220 ENOG4105CHR reductase B7O99_22225 ENOG4105C26 Dehydrogenase B7O99_22235 ENOG4105C7K acetolactate synthase B7O99_22240 ENOG4108YXU transcriptional regulator AsnC family B7O99_22245 ENOG4105FFC UPF0187 protein B7O99_22255 ENOG4107RDF Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) B7O99_22275 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) B7O99_22285 ENOG4105K5X acetyltransferase B7O99_22300 ENOG4105DMF Dehydrogenase B7O99_22305 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 B7O99_22320 ENOG4108FUF Transcriptional regulator, IclR family B7O99_22325 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7O99_22330 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) B7O99_22340 ENOG4105VG0 50S ribosomal protein l34 B7O99_22345 ENOG4105X5M RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) B7O99_22350 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) B7O99_22360 ENOG4105CH6 catalase B7O99_22365 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component B7O99_22380 ENOG4105E2B Taurine dioxygenase B7O99_22385 ENOG4105CH2 amidohydrolase B7O99_22390 ENOG4108JQ7 (ABC) transporter B7O99_22395 ENOG4105C3U ABC transporter B7O99_22410 ENOG4105DEF Extracellular solute-binding protein, family 5 B7O99_22430 ENOG41062D9 Histidine kinase B7O99_22450 ENOG4105CHM Aminotransferase B7O99_22455 ENOG4105VEQ Cold shock protein