locus-tag	class	description
B7O99_00015	COG1192	Involved in chromosome partitioning
B7O99_00025	COG1475	DNA binding
B7O99_00030	COG0252	asparaginase activity
B7O99_00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7O99_00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7O99_00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B7O99_00075	COG0081	regulation of translation
B7O99_00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B7O99_00085	COG0222	ribosome binding
B7O99_00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B7O99_00130	COG1230	cation diffusion facilitator family transporter
B7O99_00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B7O99_00145	COG0049	tRNA binding
B7O99_00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7O99_00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B7O99_00170	COG0088	Forms part of the polypeptide exit tunnel
B7O99_00175	COG0089	rRNA binding
B7O99_00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B7O99_00185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B7O99_00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B7O99_00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B7O99_00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B7O99_00205	COG0255	Belongs to the universal ribosomal protein uL29 family
B7O99_00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B7O99_00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B7O99_00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B7O99_00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B7O99_00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B7O99_00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B7O99_00255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B7O99_00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B7O99_00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B7O99_00270	COG1841	ribosomal large subunit assembly
B7O99_00280	COG0201	protein transport
B7O99_00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B7O99_00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B7O99_00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B7O99_00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B7O99_00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B7O99_00310	COG0202	RNA polymerase activity
B7O99_00315	COG0203	ribosomal protein L17
B7O99_00320	COG0537	adenosine 5'-monophosphoramidase activity
B7O99_00325	COG1324	tolerance protein
B7O99_00330	COG4232	protein-disulfide reductase activity
B7O99_00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B7O99_00355	COG1333	cytochrome c biogenesis protein
B7O99_00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7O99_00375	COG1965	Belongs to the frataxin family
B7O99_00390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B7O99_00410	COG2814	Major facilitator Superfamily
B7O99_00465	COG0438	transferase activity, transferring glycosyl groups
B7O99_00485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_00510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B7O99_00515	COG2186	Transcriptional regulator
B7O99_00535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7O99_00540	COG1956	GAF domain-containing protein
B7O99_00545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7O99_00575	COG0531	amino acid
B7O99_00605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B7O99_00610	COG3568	Endonuclease Exonuclease Phosphatase
B7O99_00615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7O99_00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7O99_00645	COG0367	asparagine synthase
B7O99_00665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B7O99_00670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B7O99_00710	COG0367	asparagine synthase
B7O99_00715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B7O99_00740	COG0367	asparagine synthase
B7O99_00750	COG0438	transferase activity, transferring glycosyl groups
B7O99_00770	COG0438	transferase activity, transferring glycosyl groups
B7O99_00775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7O99_00780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7O99_00810	COG0859	PFAM glycosyl transferase family 9
B7O99_00840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7O99_00845	COG1127	ABC transporter
B7O99_00865	COG1686	Belongs to the peptidase S11 family
B7O99_00905	COG2096	Adenosyltransferase
B7O99_00920	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B7O99_00925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7O99_00930	COG0523	cobalamin synthesis protein
B7O99_00935	COG0735	belongs to the Fur family
B7O99_00940	COG1121	(ABC) transporter
B7O99_00950	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7O99_00960	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B7O99_00970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B7O99_00980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B7O99_00985	COG1560	Kdo2-lipid A biosynthetic process
B7O99_00995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B7O99_01010	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7O99_01015	COG1950	PFAM Membrane protein of
B7O99_01025	COG0583	DNA-binding transcription factor activity
B7O99_01035	COG0477	Major facilitator Superfamily
B7O99_01060	COG0513	Belongs to the DEAD box helicase family
B7O99_01070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7O99_01075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7O99_01090	COG0735	belongs to the Fur family
B7O99_01100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7O99_01110	COG0438	transferase activity, transferring glycosyl groups
B7O99_01135	COG0640	Transcriptional regulator
B7O99_01175	COG0411	ABC transporter
B7O99_01195	COG0583	DNA-binding transcription factor activity
B7O99_01210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B7O99_01215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7O99_01220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_01235	COG0758	DNA mediated transformation
B7O99_01240	COG1522	sequence-specific DNA binding
B7O99_01250	COG0242	peptide deformylase activity
B7O99_01265	COG0546	phosphoglycolate phosphatase activity
B7O99_01290	COG1942	4-Oxalocrotonate Tautomerase
B7O99_01295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_01330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B7O99_01330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7O99_01340	COG5000	phosphorelay sensor kinase activity
B7O99_01345	COG2204	response regulator
B7O99_01350	COG0569	domain protein
B7O99_01370	COG2068	MobA-Related Protein
B7O99_01385	COG0596	Alpha beta hydrolase
B7O99_01390	COG2309	aminopeptidase activity
B7O99_01395	COG1335	isochorismatase
B7O99_01420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_01445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7O99_01450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_01465	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B7O99_01470	COG2226	methyltransferase
B7O99_01485	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_01495	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B7O99_01500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7O99_01515	COG4942	peptidase
B7O99_01520	COG0793	Belongs to the peptidase S41A family
B7O99_01525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7O99_01540	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B7O99_01545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7O99_01580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B7O99_01585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B7O99_01590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B7O99_01600	COG0142	geranyltranstransferase activity
B7O99_01610	COG0583	DNA-binding transcription factor activity
B7O99_01620	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
B7O99_01625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_01640	COG2994	toxin metabolic process
B7O99_01650	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
B7O99_01655	COG2274	protein secretion by the type I secretion system
B7O99_01660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7O99_01665	COG1538	Outer membrane efflux protein
B7O99_01680	COG0765	amino acid transport
B7O99_01685	COG0765	amino acid transport
B7O99_01690	COG1126	abc transporter atp-binding protein
B7O99_01710	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_01720	COG1802	Transcriptional regulator
B7O99_01735	COG1802	Transcriptional regulator
B7O99_01745	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_01755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_01765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7O99_01785	COG0583	DNA-binding transcription factor activity
B7O99_01790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_01795	COG2301	Belongs to the HpcH HpaI aldolase family
B7O99_01800	COG2188	Transcriptional regulator
B7O99_01845	COG0583	DNA-binding transcription factor activity
B7O99_01850	COG1024	Enoyl-CoA hydratase
B7O99_01865	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_01875	COG0411	ABC transporter
B7O99_01885	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_01895	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_01900	COG1902	pentaerythritol trinitrate reductase activity
B7O99_01925	COG0745	RESPONSE REGULATOR receiver
B7O99_01955	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B7O99_01965	COG2890	protein-(glutamine-N5) methyltransferase activity
B7O99_01970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B7O99_01980	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_02035	COG0410	ABC transporter
B7O99_02050	COG4211	Belongs to the binding-protein-dependent transport system permease family
B7O99_02060	COG0683	leucine binding
B7O99_02065	COG0154	amidase activity
B7O99_02070	COG0288	reversible hydration of carbon dioxide
B7O99_02090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7O99_02105	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7O99_02115	COG1414	Transcriptional regulator
B7O99_02120	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_02125	COG2031	fatty acid transporter
B7O99_02130	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_02165	COG2808	Putative FMN-binding domain
B7O99_02170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7O99_02175	COG0747	negative chemotaxis
B7O99_02180	COG0657	acetylesterase activity
B7O99_02190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7O99_02195	COG2207	Transcriptional regulator
B7O99_02200	COG0129	dihydroxy-acid dehydratase activity
B7O99_02220	COG1538	Outer membrane efflux protein
B7O99_02235	COG0583	DNA-binding transcription factor activity
B7O99_02240	COG0628	permease
B7O99_02250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7O99_02255	COG0251	oxidation-reduction process
B7O99_02265	COG0330	HflC and HflK could
B7O99_02285	COG0583	DNA-binding transcription factor activity
B7O99_02320	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_02325	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_02330	COG1414	Transcriptional regulator
B7O99_02335	COG1024	Enoyl-CoA hydratase
B7O99_02340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7O99_02345	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_02350	COG0604	alcohol dehydrogenase
B7O99_02355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_02360	COG0583	DNA-binding transcription factor activity
B7O99_02370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_02385	COG0251	oxidation-reduction process
B7O99_02395	COG2031	fatty acid transporter
B7O99_02425	COG1278	Cold shock
B7O99_02430	COG0583	DNA-binding transcription factor activity
B7O99_02440	COG3119	arylsulfatase activity
B7O99_02455	COG1228	amidohydrolase
B7O99_02460	COG0523	cobalamin synthesis protein
B7O99_02465	COG1819	glycosyl
B7O99_02535	COG0625	glutathione transferase activity
B7O99_02550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7O99_02555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7O99_02560	COG1652	LysM domain
B7O99_02575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7O99_02585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_02590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7O99_02625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7O99_02680	COG0583	DNA-binding transcription factor activity
B7O99_02685	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_02690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B7O99_02695	COG1024	Enoyl-CoA hydratase
B7O99_02700	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_02725	COG0028	Belongs to the TPP enzyme family
B7O99_02740	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_02745	COG1414	Transcriptional regulator
B7O99_02765	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_02770	COG1609	Transcriptional regulator
B7O99_02800	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7O99_02805	COG1024	Enoyl-CoA hydratase
B7O99_02820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_02825	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_02830	COG0583	DNA-binding transcription factor activity
B7O99_02845	COG1960	acyl-CoA dehydrogenase activity
B7O99_02860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B7O99_02870	COG1053	succinate dehydrogenase
B7O99_02870	COG3976	FMN-binding domain protein
B7O99_02885	COG0410	ABC transporter
B7O99_02905	COG0683	leucine binding
B7O99_02910	COG1309	transcriptional regulator
B7O99_02930	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_02935	COG1960	acyl-CoA dehydrogenase activity
B7O99_02940	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_02945	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_02955	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B7O99_02965	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7O99_02980	COG2030	dehydratase
B7O99_02990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_02995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_03000	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_03025	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_03045	COG1902	pentaerythritol trinitrate reductase activity
B7O99_03045	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7O99_03060	COG0427	acetyl-CoA hydrolase
B7O99_03065	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_03080	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B7O99_03100	COG0183	Belongs to the thiolase family
B7O99_03105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7O99_03115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_03120	COG0583	DNA-binding transcription factor activity
B7O99_03125	COG1960	acyl-CoA dehydrogenase activity
B7O99_03140	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
B7O99_03165	COG1309	transcriptional regulator
B7O99_03175	COG1024	Enoyl-CoA hydratase
B7O99_03195	COG1024	Enoyl-CoA hydratase
B7O99_03200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_03205	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_03210	COG1454	alcohol dehydrogenase
B7O99_03215	COG1024	Enoyl-CoA hydratase
B7O99_03235	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_03240	COG0431	NADPH-dependent FMN reductase
B7O99_03245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_03250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7O99_03265	COG1414	Transcriptional regulator
B7O99_03270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7O99_03275	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_03280	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_03305	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_03325	COG1024	Enoyl-CoA hydratase
B7O99_03335	COG1960	acyl-CoA dehydrogenase activity
B7O99_03340	COG1024	Enoyl-CoA hydratase
B7O99_03345	COG0183	Belongs to the thiolase family
B7O99_03350	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_03365	COG0583	DNA-binding transcription factor activity
B7O99_03370	COG2267	carboxylic ester hydrolase activity
B7O99_03385	COG0625	glutathione transferase activity
B7O99_03390	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_03400	COG2186	Transcriptional regulator
B7O99_03405	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_03410	COG0626	cystathionine gamma-synthase activity
B7O99_03450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7O99_03480	COG1414	Transcriptional regulator
B7O99_03490	COG0154	amidase activity
B7O99_03550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_03565	COG3135	benzoate transporter
B7O99_03590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7O99_03610	COG5444	nuclease activity
B7O99_03730	COG3468	outer membrane autotransporter barrel domain protein
B7O99_03740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B7O99_03795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7O99_03840	COG0489	protein tyrosine kinase activity
B7O99_03855	COG0717	Belongs to the dCTP deaminase family
B7O99_03880	COG1982	Orn Lys Arg decarboxylase major
B7O99_03885	COG2081	HI0933 family
B7O99_03890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7O99_03905	COG0509	glycine decarboxylation via glycine cleavage system
B7O99_03930	COG1024	Enoyl-CoA hydratase
B7O99_03950	COG4172	Belongs to the ABC transporter superfamily
B7O99_03955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_03960	COG0601	transmembrane transport
B7O99_03965	COG0747	negative chemotaxis
B7O99_03990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B7O99_04000	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B7O99_04005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7O99_04010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7O99_04025	COG0438	transferase activity, transferring glycosyl groups
B7O99_04040	COG0438	transferase activity, transferring glycosyl groups
B7O99_04045	COG0438	transferase activity, transferring glycosyl groups
B7O99_04050	COG0166	Belongs to the GPI family
B7O99_04065	COG0277	FAD linked oxidase domain protein
B7O99_04070	COG0745	RESPONSE REGULATOR receiver
B7O99_04075	COG0642	Histidine kinase
B7O99_04080	COG1368	sulfuric ester hydrolase activity
B7O99_04090	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B7O99_04145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7O99_04150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B7O99_04155	COG0193	aminoacyl-tRNA hydrolase activity
B7O99_04165	COG0012	GTP binding
B7O99_04180	COG0745	RESPONSE REGULATOR receiver
B7O99_04185	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_04190	COG1309	transcriptional regulator
B7O99_04200	COG2814	Major facilitator Superfamily
B7O99_04225	COG0281	malic enzyme
B7O99_04225	COG0280	phosphate acetyltransferase
B7O99_04235	COG0601	transmembrane transport
B7O99_04240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_04245	COG4172	Belongs to the ABC transporter superfamily
B7O99_04260	COG0583	DNA-binding transcription factor activity
B7O99_04275	COG0640	Transcriptional regulator
B7O99_04290	COG3135	benzoate transporter
B7O99_04295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7O99_04300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B7O99_04305	COG0742	ribosomal rna small subunit methyltransferase
B7O99_04320	COG3639	organic phosphonate transmembrane transporter activity
B7O99_04325	COG3639	organic phosphonate transmembrane transporter activity
B7O99_04355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B7O99_04360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7O99_04370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7O99_04375	COG1058	Belongs to the CinA family
B7O99_04375	COG1546	Belongs to the CinA family
B7O99_04380	COG0284	orotidine-5'-phosphate decarboxylase activity
B7O99_04385	COG1252	NADH dehydrogenase
B7O99_04405	COG0459	protein refolding
B7O99_04410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B7O99_04430	COG1053	succinate dehydrogenase
B7O99_04440	COG0583	DNA-binding transcription factor activity
B7O99_04450	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_04455	COG1414	Transcriptional regulator
B7O99_04470	COG1335	isochorismatase
B7O99_04485	COG0405	Gamma-glutamyltransferase
B7O99_04500	COG1960	acyl-CoA dehydrogenase activity
B7O99_04505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_04510	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_04515	COG0583	DNA-binding transcription factor activity
B7O99_04540	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_04545	COG0583	DNA-binding transcription factor activity
B7O99_04550	COG5001	Diguanylate cyclase
B7O99_04605	COG1024	Enoyl-CoA hydratase
B7O99_04605	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_04610	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_04625	COG1024	Enoyl-CoA hydratase
B7O99_04630	COG1024	Enoyl-CoA hydratase
B7O99_04635	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_04640	COG1960	acyl-CoA dehydrogenase activity
B7O99_04680	COG3685	Protein conserved in bacteria
B7O99_04690	COG0387	Pfam Sodium calcium exchanger
B7O99_04695	COG3795	YCII-related domain
B7O99_04720	COG0154	amidase activity
B7O99_04725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_04730	COG1024	Enoyl-CoA hydratase
B7O99_04740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_04755	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_04760	COG1414	Transcriptional regulator
B7O99_04775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7O99_04780	COG0251	oxidation-reduction process
B7O99_04785	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_04800	COG0410	ABC transporter
B7O99_04805	COG1902	pentaerythritol trinitrate reductase activity
B7O99_04810	COG0583	DNA-binding transcription factor activity
B7O99_04820	COG0590	tRNA wobble adenosine to inosine editing
B7O99_04825	COG2807	transmembrane transport
B7O99_04830	COG0307	riboflavin synthase, alpha
B7O99_04835	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_04840	COG1522	sequence-specific DNA binding
B7O99_04850	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_04860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_04900	COG1418	mRNA catabolic process
B7O99_04910	COG1335	isochorismatase
B7O99_04935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7O99_04940	COG2274	protein secretion by the type I secretion system
B7O99_04950	COG1538	Outer membrane efflux protein
B7O99_04965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7O99_04975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_04985	COG1309	transcriptional regulator
B7O99_04990	COG1960	acyl-CoA dehydrogenase activity
B7O99_04995	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_05000	COG2076	Multidrug Resistance protein
B7O99_05005	COG1309	transcriptional regulator
B7O99_05025	COG0840	transmembrane signaling receptor activity
B7O99_05040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7O99_05065	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_05075	COG1024	Enoyl-CoA hydratase
B7O99_05085	COG2203	Gaf domain
B7O99_05085	COG2199	diguanylate cyclase activity
B7O99_05105	COG0154	amidase activity
B7O99_05135	COG3945	hemerythrin HHE cation binding domain
B7O99_05150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7O99_05150	COG2169	Transcriptional regulator
B7O99_05170	COG1271	oxidase subunit
B7O99_05175	COG1294	oxidase, subunit
B7O99_05185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7O99_05220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7O99_05245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7O99_05255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7O99_05260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7O99_05270	COG2070	2-Nitropropane dioxygenase
B7O99_05285	COG1917	Cupin 2, conserved barrel domain protein
B7O99_05285	COG2207	Transcriptional regulator
B7O99_05305	COG2900	Belongs to the SlyX family
B7O99_05315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7O99_05345	COG0583	DNA-binding transcription factor activity
B7O99_05360	COG0583	DNA-binding transcription factor activity
B7O99_05385	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B7O99_05395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7O99_05400	COG1845	cytochrome c oxidase, subunit III
B7O99_05405	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7O99_05410	COG0640	Transcriptional regulator
B7O99_05500	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_05510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7O99_05515	COG1845	cytochrome c oxidase, subunit III
B7O99_05520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7O99_05525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7O99_05530	COG0477	Major facilitator Superfamily
B7O99_05545	COG5006	permease, DMT superfamily
B7O99_05565	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B7O99_05580	COG3383	formate dehydrogenase (NAD+) activity
B7O99_05600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7O99_05605	COG0303	'Molybdopterin
B7O99_05610	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7O99_05620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B7O99_05635	COG0412	Dienelactone hydrolase
B7O99_05645	COG0678	peroxiredoxin activity
B7O99_05655	COG0697	spore germination
B7O99_05660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B7O99_05700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7O99_05705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7O99_05710	COG1335	isochorismatase
B7O99_05715	COG0523	cobalamin synthesis protein
B7O99_05720	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_05725	COG1053	succinate dehydrogenase
B7O99_05735	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_05745	COG1802	Transcriptional regulator
B7O99_05765	COG0667	Aldo Keto reductase
B7O99_05775	COG4535	Mg2 and Co2 transporter CorC
B7O99_05785	COG1702	phosphate starvation-inducible protein PhoH
B7O99_05800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7O99_05805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7O99_05810	COG1862	Preprotein translocase
B7O99_05815	COG0343	queuine tRNA-ribosyltransferase activity
B7O99_05825	COG2027	D-alanyl-D-alanine carboxypeptidase
B7O99_05830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B7O99_05840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7O99_05840	COG1648	precorrin-2 dehydrogenase activity
B7O99_05870	COG0741	lytic transglycosylase activity
B7O99_05875	COG0436	Aminotransferase
B7O99_05885	COG0280	phosphate acetyltransferase
B7O99_05885	COG0281	malic enzyme
B7O99_05895	COG2732	(Barnase) inhibitor
B7O99_05900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7O99_05905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7O99_05910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7O99_05920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B7O99_05925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7O99_05940	COG0625	glutathione transferase activity
B7O99_05970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7O99_05980	COG0306	phosphate transporter
B7O99_05985	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7O99_05995	COG0739	heme binding
B7O99_06005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B7O99_06055	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B7O99_06075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B7O99_06080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B7O99_06085	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7O99_06090	COG0009	L-threonylcarbamoyladenylate synthase
B7O99_06095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_06100	COG1414	Transcriptional regulator
B7O99_06115	COG0765	amino acid transport
B7O99_06120	COG1126	abc transporter atp-binding protein
B7O99_06140	COG0028	Belongs to the TPP enzyme family
B7O99_06145	COG0583	DNA-binding transcription factor activity
B7O99_06150	COG4974	Belongs to the 'phage' integrase family
B7O99_06155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7O99_06160	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B7O99_06170	COG1686	Belongs to the peptidase S11 family
B7O99_06190	COG1074	ATP-dependent DNA helicase activity
B7O99_06200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7O99_06210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7O99_06215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_06220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7O99_06230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_06235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7O99_06240	COG0505	Belongs to the CarA family
B7O99_06245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7O99_06275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7O99_06305	COG1053	succinate dehydrogenase
B7O99_06305	COG3976	FMN-binding domain protein
B7O99_06310	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_06340	COG3842	ATPase activity
B7O99_06350	COG0395	ABC-type sugar transport system, permease component
B7O99_06385	COG0420	3'-5' exonuclease activity
B7O99_06400	COG2111	Na H antiporter
B7O99_06400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7O99_06405	COG1006	Multisubunit Na H antiporter MnhC subunit
B7O99_06410	COG0651	ATP synthesis coupled electron transport
B7O99_06415	COG1863	multisubunit Na H antiporter MnhE subunit
B7O99_06420	COG2212	antiporter activity
B7O99_06440	COG0590	tRNA wobble adenosine to inosine editing
B7O99_06445	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7O99_06450	COG1024	Enoyl-CoA hydratase
B7O99_06455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B7O99_06465	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_06470	COG0488	(ABC) transporter
B7O99_06500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7O99_06505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7O99_06510	COG2252	PERMEase
B7O99_06520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B7O99_06525	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B7O99_06530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7O99_06560	COG0789	Transcriptional regulator
B7O99_06570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7O99_06570	COG0678	peroxiredoxin activity
B7O99_06580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B7O99_06585	COG0584	glycerophosphoryl diester phosphodiesterase
B7O99_06590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7O99_06600	COG4181	ATPase activity
B7O99_06640	COG4336	lyase activity
B7O99_06655	COG2197	response regulator
B7O99_06660	COG3064	Membrane
B7O99_06660	COG3210	domain, Protein
B7O99_06660	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B7O99_06670	COG3121	Chaperone
B7O99_06675	COG3188	usher protein
B7O99_06680	COG3539	Fimbrial protein
B7O99_06685	COG2831	hemolysin activation secretion protein
B7O99_06700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7O99_06725	COG0583	DNA-binding transcription factor activity
B7O99_06745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_06750	COG0765	amino acid transport
B7O99_06755	COG1126	abc transporter atp-binding protein
B7O99_06760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7O99_06765	COG1758	RNA polymerase activity
B7O99_06770	COG0194	GDP metabolic process
B7O99_06775	COG3258	Cytochrome c
B7O99_06780	COG2863	cytochrome
B7O99_06785	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_06790	COG0791	NLP P60 protein
B7O99_06795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7O99_06840	COG5002	protein histidine kinase activity
B7O99_06840	COG5001	Diguanylate cyclase
B7O99_06850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7O99_06860	COG3852	Histidine kinase
B7O99_06865	COG2204	response regulator
B7O99_06870	COG0583	DNA-binding transcription factor activity
B7O99_06875	COG1741	Belongs to the pirin family
B7O99_06880	COG1741	Belongs to the pirin family
B7O99_06885	COG3842	ATPase activity
B7O99_06895	COG1840	ABC-type Fe3 transport system, periplasmic component
B7O99_06905	COG0583	DNA-binding transcription factor activity
B7O99_06910	COG2814	Major facilitator Superfamily
B7O99_06915	COG0656	L-ascorbic acid biosynthetic process
B7O99_06930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7O99_06935	COG0583	DNA-binding transcription factor activity
B7O99_06950	COG0783	Belongs to the Dps family
B7O99_06965	COG0463	Glycosyl transferase, family 2
B7O99_06985	COG0438	transferase activity, transferring glycosyl groups
B7O99_07000	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7O99_07020	COG0300	oxidoreductase activity
B7O99_07055	COG0395	ABC-type sugar transport system, permease component
B7O99_07060	COG1175	transmembrane transport
B7O99_07065	COG1653	transport
B7O99_07075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B7O99_07085	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_07095	COG0411	ABC transporter
B7O99_07100	COG0410	ABC transporter
B7O99_07105	COG1794	racemase activity, acting on amino acids and derivatives
B7O99_07110	COG0625	glutathione transferase activity
B7O99_07115	COG2133	pyrroloquinoline quinone binding
B7O99_07140	COG2363	Small membrane protein
B7O99_07180	COG0095	Lipoate-protein ligase
B7O99_07195	COG0625	glutathione transferase activity
B7O99_07200	COG0386	Belongs to the glutathione peroxidase family
B7O99_07240	COG2259	Doxx family
B7O99_07255	COG0667	Aldo Keto reductase
B7O99_07285	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B7O99_07300	COG1640	4-alpha-glucanotransferase
B7O99_07350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B7O99_07375	COG0747	negative chemotaxis
B7O99_07380	COG0601	transmembrane transport
B7O99_07385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_07390	COG4172	Belongs to the ABC transporter superfamily
B7O99_07445	COG0425	Belongs to the sulfur carrier protein TusA family
B7O99_07460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7O99_07465	COG0336	Belongs to the RNA methyltransferase TrmD family
B7O99_07470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7O99_07480	COG0642	Histidine kinase
B7O99_07485	COG0745	RESPONSE REGULATOR receiver
B7O99_07500	COG0105	UTP biosynthetic process
B7O99_07515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B7O99_07520	COG0124	histidyl-tRNA synthetase
B7O99_07525	COG2976	Protein conserved in bacteria
B7O99_07530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7O99_07535	COG1160	GTP binding
B7O99_07545	COG1923	regulation of RNA biosynthetic process
B7O99_07550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7O99_07555	COG0330	HflC and HflK could
B7O99_07560	COG0330	HflC and HflK could
B7O99_07565	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B7O99_07580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B7O99_07590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7O99_07650	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_07655	COG0683	leucine binding
B7O99_07660	COG4638	Rieske (2fe-2S)
B7O99_07665	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7O99_07670	COG1024	Enoyl-CoA hydratase
B7O99_07680	COG0633	Ferredoxin
B7O99_07685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_07700	COG0183	Belongs to the thiolase family
B7O99_07710	COG4692	amylo-alpha-1,6-glucosidase activity
B7O99_07715	COG0583	DNA-binding transcription factor activity
B7O99_07735	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_07740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_07760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B7O99_07770	COG3829	transcription factor binding
B7O99_07800	COG0833	amino acid
B7O99_07820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_07825	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B7O99_07830	COG0439	Biotin carboxylase
B7O99_07845	COG0395	ABC-type sugar transport system, permease component
B7O99_07850	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7O99_07865	COG1414	Transcriptional regulator
B7O99_07870	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_07880	COG2188	Transcriptional regulator
B7O99_07905	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_07910	COG0583	DNA-binding transcription factor activity
B7O99_07930	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7O99_07940	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7O99_07950	COG1228	amidohydrolase
B7O99_07955	COG2267	carboxylic ester hydrolase activity
B7O99_07980	COG0861	Integral membrane protein TerC family
B7O99_07985	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_08000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7O99_08040	COG3119	arylsulfatase activity
B7O99_08060	COG2197	response regulator
B7O99_08070	COG2944	sequence-specific DNA binding
B7O99_08075	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
B7O99_08080	COG0625	glutathione transferase activity
B7O99_08095	COG3119	arylsulfatase activity
B7O99_08110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_08115	COG0183	Belongs to the thiolase family
B7O99_08130	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_08135	COG0583	DNA-binding transcription factor activity
B7O99_08140	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_08150	COG1024	Enoyl-CoA hydratase
B7O99_08160	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_08165	COG1024	Enoyl-CoA hydratase
B7O99_08165	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_08175	COG1454	alcohol dehydrogenase
B7O99_08180	COG0824	Thioesterase
B7O99_08205	COG0431	NADPH-dependent FMN reductase
B7O99_08235	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_08240	COG0583	DNA-binding transcription factor activity
B7O99_08265	COG0330	HflC and HflK could
B7O99_08285	COG3043	anaerobic respiration
B7O99_08290	COG3005	denitrification pathway
B7O99_08325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7O99_08355	COG4948	Mandelate Racemase Muconate Lactonizing
B7O99_08360	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_08390	COG0583	DNA-binding transcription factor activity
B7O99_08410	COG1695	Transcriptional regulator
B7O99_08420	COG3568	Endonuclease Exonuclease Phosphatase
B7O99_08430	COG0392	lysyltransferase activity
B7O99_08445	COG1546	Belongs to the CinA family
B7O99_08445	COG1058	Belongs to the CinA family
B7O99_08465	COG4575	ribosome binding
B7O99_08470	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B7O99_08480	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_08535	COG0028	Belongs to the TPP enzyme family
B7O99_08540	COG2204	response regulator
B7O99_08545	COG2204	response regulator
B7O99_08565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7O99_08585	COG0181	hydroxymethylbilane synthase activity
B7O99_08590	COG0861	Integral membrane protein TerC family
B7O99_08595	COG0861	Integral membrane protein TerC family
B7O99_08600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B7O99_08605	COG0045	succinate-CoA ligase (ADP-forming) activity
B7O99_08615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B7O99_08620	COG0583	DNA-binding transcription factor activity
B7O99_08625	COG2137	regulation of response to DNA damage stimulus
B7O99_08630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B7O99_08640	COG0642	Histidine kinase
B7O99_08650	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_08650	COG1024	Enoyl-CoA hydratase
B7O99_08655	COG3842	ATPase activity
B7O99_08670	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_08685	COG0183	Belongs to the thiolase family
B7O99_08690	COG0583	DNA-binding transcription factor activity
B7O99_08695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_08710	COG0540	Belongs to the ATCase OTCase family
B7O99_08750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7O99_08765	COG1522	sequence-specific DNA binding
B7O99_08775	COG2367	Beta-lactamase
B7O99_08790	COG0500	methyltransferase
B7O99_08815	COG0776	regulation of translation
B7O99_08830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B7O99_08835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B7O99_08855	COG0004	ammonium transporteR
B7O99_08860	COG3468	outer membrane autotransporter barrel domain protein
B7O99_08875	COG1309	transcriptional regulator
B7O99_08900	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_08910	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7O99_08910	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7O99_08910	COG0506	proline dehydrogenase activity
B7O99_08920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7O99_08920	COG3008	intermembrane lipid transfer
B7O99_08925	COG2995	paraquat-inducible protein a
B7O99_08930	COG0542	response to heat
B7O99_08935	COG4953	penicillin-binding protein 1C
B7O99_08945	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B7O99_08950	COG1278	Cold shock
B7O99_08960	COG0183	Belongs to the thiolase family
B7O99_08965	COG0038	chloride channel
B7O99_08970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7O99_08975	COG1570	exodeoxyribonuclease VII activity
B7O99_08980	COG0811	peptide transport
B7O99_08985	COG0848	biopolymer transport protein
B7O99_08990	COG1663	tetraacyldisaccharide 4'-kinase activity
B7O99_08995	COG2835	tetraacyldisaccharide 4'-kinase activity
B7O99_09015	COG0728	peptidoglycan biosynthetic process
B7O99_09025	COG0268	Binds directly to 16S ribosomal RNA
B7O99_09045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B7O99_09050	COG2186	Transcriptional regulator
B7O99_09070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7O99_09080	COG0583	DNA-binding transcription factor activity
B7O99_09095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B7O99_09100	COG0137	argininosuccinate synthase activity
B7O99_09105	COG3158	transport of potassium into the cell
B7O99_09110	COG0642	Histidine kinase
B7O99_09115	COG0745	RESPONSE REGULATOR receiver
B7O99_09140	COG0776	regulation of translation
B7O99_09145	COG3128	pkhd-type hydroxylase
B7O99_09155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7O99_09160	COG0557	exoribonuclease II activity
B7O99_09180	COG2153	protein acetylation
B7O99_09185	COG0679	Auxin Efflux Carrier
B7O99_09195	COG0069	glutamate synthase activity
B7O99_09200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7O99_09210	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B7O99_09250	COG3706	GGDEF domain
B7O99_09285	COG3909	cytochrome
B7O99_09290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7O99_09295	COG0625	glutathione transferase activity
B7O99_09300	COG0730	response to heat
B7O99_09310	COG0583	DNA-binding transcription factor activity
B7O99_09325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B7O99_09330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B7O99_09335	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B7O99_09350	COG2819	hydrolase of the alpha beta superfamily
B7O99_09355	COG0247	lactate metabolic process
B7O99_09365	COG0277	FAD linked oxidase domain protein
B7O99_09370	COG0277	FAD linked oxidase domain protein
B7O99_09375	COG3064	Membrane
B7O99_09375	COG3210	domain, Protein
B7O99_09375	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B7O99_09375	COG3064	Membrane
B7O99_09375	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B7O99_09375	COG3210	domain, Protein
B7O99_09380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7O99_09385	COG0312	modulator of DNA gyrase
B7O99_09390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7O99_09405	COG0308	aminopeptidase N
B7O99_09410	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B7O99_09430	COG0436	Aminotransferase
B7O99_09435	COG3737	Protein of unknown function (DUF498/DUF598)
B7O99_09440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7O99_09445	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B7O99_09450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B7O99_09460	COG0305	Participates in initiation and elongation during chromosome replication
B7O99_09475	COG0359	binds to the 23S rRNA
B7O99_09480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7O99_09485	COG2965	DNA replication, synthesis of RNA primer
B7O99_09490	COG0360	Binds together with S18 to 16S ribosomal RNA
B7O99_09495	COG1469	GTP cyclohydrolase I activity
B7O99_09500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B7O99_09505	COG0142	geranyltranstransferase activity
B7O99_09510	COG1722	exodeoxyribonuclease VII activity
B7O99_09520	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_09555	COG1840	ABC-type Fe3 transport system, periplasmic component
B7O99_09560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7O99_09565	COG1178	ABC-type Fe3 transport system permease component
B7O99_09570	COG3842	ATPase activity
B7O99_09575	COG0583	DNA-binding transcription factor activity
B7O99_09595	COG0501	Belongs to the peptidase M48B family
B7O99_09605	COG0697	spore germination
B7O99_09615	COG1846	Transcriptional regulator
B7O99_09635	COG0473	3-isopropylmalate dehydrogenase activity
B7O99_09645	COG0747	negative chemotaxis
B7O99_09655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_09665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7O99_09690	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_09700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7O99_09710	COG0217	transcriptional regulatory protein
B7O99_09715	COG0151	Belongs to the GarS family
B7O99_09720	COG0408	coproporphyrinogen oxidase activity
B7O99_09730	COG0799	negative regulation of ribosome biogenesis
B7O99_09740	COG0424	maF-like protein
B7O99_09745	COG3468	outer membrane autotransporter barrel domain protein
B7O99_09785	COG0385	Bile acid
B7O99_09790	COG0427	acetyl-CoA hydrolase
B7O99_09795	COG0583	DNA-binding transcription factor activity
B7O99_09800	COG3264	Mechanosensitive ion channel
B7O99_09800	COG1511	domain protein
B7O99_09815	COG0730	response to heat
B7O99_09820	COG0697	spore germination
B7O99_09855	COG2885	chlorophyll binding
B7O99_09875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7O99_09880	COG3384	dioxygenase
B7O99_09895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B7O99_09900	COG3474	cytochrome
B7O99_09965	COG4964	Belongs to the GSP D family
B7O99_10015	COG4172	Belongs to the ABC transporter superfamily
B7O99_10020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_10025	COG0601	transmembrane transport
B7O99_10030	COG0747	negative chemotaxis
B7O99_10040	COG0598	Magnesium transport protein CorA
B7O99_10060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7O99_10070	COG0483	inositol monophosphate 1-phosphatase activity
B7O99_10095	COG1045	serine acetyltransferase
B7O99_10100	COG0166	Belongs to the GPI family
B7O99_10115	COG2197	response regulator
B7O99_10130	COG0183	Belongs to the thiolase family
B7O99_10145	COG1024	Enoyl-CoA hydratase
B7O99_10145	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_10150	COG0183	Belongs to the thiolase family
B7O99_10160	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_10170	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_10185	COG1017	nitric oxide dioxygenase activity
B7O99_10185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7O99_10190	COG2010	Cytochrome c
B7O99_10190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7O99_10195	COG1335	isochorismatase
B7O99_10200	COG2309	aminopeptidase activity
B7O99_10205	COG0596	Alpha beta hydrolase
B7O99_10220	COG2080	2 iron, 2 sulfur cluster binding
B7O99_10250	COG1846	Transcriptional regulator
B7O99_10270	COG0726	polysaccharide deacetylase
B7O99_10270	COG1649	PFAM Uncharacterised BCR, COG1649
B7O99_10275	COG1215	transferase activity, transferring glycosyl groups
B7O99_10285	COG1902	pentaerythritol trinitrate reductase activity
B7O99_10310	COG0251	oxidation-reduction process
B7O99_10320	COG1832	CoA-binding protein
B7O99_10325	COG1414	Transcriptional regulator
B7O99_10330	COG1902	pentaerythritol trinitrate reductase activity
B7O99_10330	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7O99_10340	COG3842	ATPase activity
B7O99_10350	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7O99_10365	COG0583	DNA-binding transcription factor activity
B7O99_10375	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_10385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7O99_10400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B7O99_10425	COG0527	aspartate kinase activity
B7O99_10435	COG0825	malonyl-CoA metabolic process
B7O99_10445	COG0215	cysteine-tRNA ligase activity
B7O99_10450	COG3063	Type IV pilus biogenesis stability protein PilW
B7O99_10460	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7O99_10465	COG1968	undecaprenyl-diphosphatase activity
B7O99_10470	COG1253	flavin adenine dinucleotide binding
B7O99_10495	COG0668	transmembrane transport
B7O99_10530	COG3360	Dodecin
B7O99_10540	COG2850	peptidyl-arginine hydroxylation
B7O99_10550	COG3539	Fimbrial protein
B7O99_10555	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B7O99_10560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7O99_10565	COG1994	Peptidase M50
B7O99_10570	COG0009	L-threonylcarbamoyladenylate synthase
B7O99_10575	COG2321	neutral zinc metallopeptidase
B7O99_10615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7O99_10620	COG1366	Belongs to the anti-sigma-factor antagonist family
B7O99_10625	COG2172	sigma factor antagonist activity
B7O99_10630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7O99_10640	COG2770	Histidine kinase
B7O99_10640	COG2208	phosphoserine phosphatase activity
B7O99_10675	COG4792	protein secretion
B7O99_10680	COG4791	protein targeting
B7O99_10685	COG4794	Type iii secretion
B7O99_10695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7O99_10725	COG4669	(LipO)protein
B7O99_10825	COG0251	oxidation-reduction process
B7O99_10865	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_10875	COG0411	ABC transporter
B7O99_10885	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_10915	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7O99_10930	COG0583	DNA-binding transcription factor activity
B7O99_10935	COG3971	2-oxopent-4-enoate hydratase activity
B7O99_10965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7O99_10980	COG0511	ligase activity, forming carbon-carbon bonds
B7O99_10990	COG0439	Biotin carboxylase
B7O99_10995	COG2188	Transcriptional regulator
B7O99_11020	COG0511	ligase activity, forming carbon-carbon bonds
B7O99_11030	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B7O99_11040	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_11050	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B7O99_11070	COG0500	methyltransferase
B7O99_11075	COG1132	(ABC) transporter
B7O99_11085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7O99_11105	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_11125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7O99_11160	COG0583	DNA-binding transcription factor activity
B7O99_11180	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_11210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7O99_11225	COG1126	abc transporter atp-binding protein
B7O99_11230	COG0765	amino acid transport
B7O99_11235	COG4597	amino acid ABC transporter
B7O99_11240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_11245	COG1473	amidohydrolase
B7O99_11250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7O99_11255	COG1522	sequence-specific DNA binding
B7O99_11265	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7O99_11275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7O99_11280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B7O99_11285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B7O99_11305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_11310	COG0154	amidase activity
B7O99_11320	COG1137	ATPase activity
B7O99_11350	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_11355	COG2072	flavoprotein involved in K transport
B7O99_11390	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_11495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7O99_11520	COG0248	Ppx GppA phosphatase
B7O99_11530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7O99_11540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7O99_11545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B7O99_11550	COG1534	Rna-binding protein
B7O99_11560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7O99_11565	COG0840	transmembrane signaling receptor activity
B7O99_11570	COG2233	PERMEase
B7O99_11585	COG3842	ATPase activity
B7O99_11595	COG0406	alpha-ribazole phosphatase activity
B7O99_11600	COG4221	oxidoreductase activity
B7O99_11615	COG0084	hydrolase, TatD family'
B7O99_11620	COG1136	(ABC) transporter
B7O99_11635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7O99_11645	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_11665	COG1022	Amp-dependent synthetase and ligase
B7O99_11695	COG1024	Enoyl-CoA hydratase
B7O99_11710	COG0633	Ferredoxin
B7O99_11725	COG0316	Belongs to the HesB IscA family
B7O99_11730	COG0822	iron-sulfur transferase activity
B7O99_11735	COG1104	cysteine desulfurase activity
B7O99_11745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7O99_11765	COG3468	outer membrane autotransporter barrel domain protein
B7O99_11775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7O99_11790	COG1960	acyl-CoA dehydrogenase activity
B7O99_11795	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_11810	COG1024	Enoyl-CoA hydratase
B7O99_11825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_11830	COG0583	DNA-binding transcription factor activity
B7O99_11835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7O99_11840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B7O99_11845	COG0740	serine-type endopeptidase activity
B7O99_11860	COG1278	Cold shock
B7O99_11870	COG1278	Cold shock
B7O99_11900	COG0436	Aminotransferase
B7O99_11915	COG2890	protein-(glutamine-N5) methyltransferase activity
B7O99_11920	COG0488	(ABC) transporter
B7O99_11925	COG4771	TonB-dependent receptor
B7O99_11930	COG0210	DNA helicase
B7O99_11945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7O99_11945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B7O99_11950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7O99_11955	COG0196	riboflavin kinase activity
B7O99_11965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B7O99_11970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7O99_11980	COG1522	sequence-specific DNA binding
B7O99_12000	COG0756	dUTP diphosphatase activity
B7O99_12005	COG1126	abc transporter atp-binding protein
B7O99_12010	COG0765	amino acid transport
B7O99_12015	COG0765	amino acid transport
B7O99_12020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_12030	COG2423	ornithine cyclodeaminase activity
B7O99_12035	COG1764	response to oxidative stress
B7O99_12045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7O99_12050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7O99_12060	COG0189	ligase activity
B7O99_12065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B7O99_12070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B7O99_12075	COG2197	response regulator
B7O99_12085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7O99_12095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B7O99_12145	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_12150	COG0101	tRNA pseudouridine synthase activity
B7O99_12160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7O99_12165	COG0473	3-isopropylmalate dehydrogenase activity
B7O99_12170	COG0066	3-isopropylmalate dehydratase activity
B7O99_12175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B7O99_12185	COG1122	ATPase activity
B7O99_12215	COG0437	4 iron, 4 sulfur cluster binding
B7O99_12220	COG3383	formate dehydrogenase (NAD+) activity
B7O99_12220	COG0243	molybdopterin cofactor binding
B7O99_12250	COG0489	protein tyrosine kinase activity
B7O99_12255	COG0746	molybdenum cofactor guanylyltransferase activity
B7O99_12260	COG0303	'Molybdopterin
B7O99_12265	COG1763	Mo-molybdopterin cofactor biosynthetic process
B7O99_12270	COG4783	chaperone-mediated protein folding
B7O99_12280	COG5001	Diguanylate cyclase
B7O99_12285	COG2205	protein histidine kinase activity
B7O99_12290	COG0745	RESPONSE REGULATOR receiver
B7O99_12295	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B7O99_12305	COG1295	ribonuclease BN
B7O99_12315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7O99_12350	COG4964	Belongs to the GSP D family
B7O99_12390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_12400	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B7O99_12425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B7O99_12430	COG3395	kinase activity
B7O99_12445	COG0662	Cupin 2, conserved barrel domain protein
B7O99_12450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7O99_12470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7O99_12485	COG2311	Membrane
B7O99_12500	COG0187	DNA topoisomerase II activity
B7O99_12510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B7O99_12525	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7O99_12530	COG1760	l-serine dehydratase
B7O99_12535	COG1283	sodium-dependent phosphate transmembrane transporter activity
B7O99_12540	COG0412	Dienelactone hydrolase
B7O99_12555	COG1611	Belongs to the LOG family
B7O99_12590	COG0195	Participates in both transcription termination and antitermination
B7O99_12590	COG2251	uridine kinase activity
B7O99_12600	COG1187	pseudouridine synthase activity
B7O99_12605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7O99_12615	COG0583	DNA-binding transcription factor activity
B7O99_12625	COG0523	cobalamin synthesis protein
B7O99_12645	COG0625	glutathione transferase activity
B7O99_12655	COG1047	Peptidyl-prolyl cis-trans
B7O99_12675	COG0254	rRNA binding
B7O99_12715	COG2304	oxidoreductase activity
B7O99_12735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7O99_12740	COG1562	ergosterol biosynthetic process
B7O99_12745	COG1562	ergosterol biosynthetic process
B7O99_12750	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B7O99_12750	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B7O99_12770	COG1131	(ABC) transporter
B7O99_12805	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B7O99_12820	COG5564	TIM-barrel signal transduction protein
B7O99_12835	COG3468	outer membrane autotransporter barrel domain protein
B7O99_12845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7O99_12860	COG0494	nUDIX hydrolase
B7O99_12865	COG3530	Putative quorum-sensing-regulated virulence factor
B7O99_12875	COG1595	DNA-templated transcription, initiation
B7O99_12880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7O99_12915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_12920	COG0765	amino acid transport
B7O99_12925	COG0765	amino acid transport
B7O99_12950	COG2841	Protein conserved in bacteria
B7O99_12955	COG2814	Major facilitator Superfamily
B7O99_12970	COG0628	permease
B7O99_12975	COG0842	Transport permease protein
B7O99_12980	COG1131	(ABC) transporter
B7O99_13025	COG3278	Belongs to the heme-copper respiratory oxidase family
B7O99_13055	COG4106	trans-aconitate 2-methyltransferase activity
B7O99_13055	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B7O99_13060	COG1380	Effector of murein hydrolase LrgA
B7O99_13065	COG1346	cytolysis
B7O99_13075	COG2224	Isocitrate lyase
B7O99_13090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7O99_13095	COG0322	excinuclease ABC activity
B7O99_13100	COG1472	Belongs to the glycosyl hydrolase 3 family
B7O99_13110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B7O99_13115	COG1538	Outer membrane efflux protein
B7O99_13125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7O99_13150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B7O99_13165	COG2032	superoxide dismutase activity
B7O99_13175	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_13180	COG1024	Enoyl-CoA hydratase
B7O99_13190	COG1802	Transcriptional regulator
B7O99_13200	COG0183	Belongs to the thiolase family
B7O99_13205	COG1942	4-Oxalocrotonate Tautomerase
B7O99_13215	COG4176	ABC-type proline glycine betaine transport system permease component
B7O99_13225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7O99_13230	COG2814	Major facilitator Superfamily
B7O99_13235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B7O99_13240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B7O99_13255	COG1846	Transcriptional regulator
B7O99_13260	COG2814	Major facilitator Superfamily
B7O99_13290	COG0154	amidase activity
B7O99_13295	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_13335	COG1530	ribonuclease E activity
B7O99_13340	COG0077	Prephenate dehydratase
B7O99_13355	COG1132	(ABC) transporter
B7O99_13360	COG0859	PFAM glycosyl transferase family 9
B7O99_13385	COG2194	sulfuric ester hydrolase activity
B7O99_13390	COG0438	transferase activity, transferring glycosyl groups
B7O99_13395	COG0463	Glycosyl transferase, family 2
B7O99_13400	COG0726	polysaccharide deacetylase
B7O99_13405	COG0438	transferase activity, transferring glycosyl groups
B7O99_13420	COG1643	Atp-dependent helicase
B7O99_13425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B7O99_13425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B7O99_13430	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B7O99_13440	COG0704	Plays a role in the regulation of phosphate uptake
B7O99_13450	COG1960	acyl-CoA dehydrogenase activity
B7O99_13465	COG2094	Belongs to the DNA glycosylase MPG family
B7O99_13475	COG1177	transmembrane transport
B7O99_13480	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7O99_13485	COG3842	ATPase activity
B7O99_13490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7O99_13495	COG3642	lipopolysaccharide core region biosynthetic process
B7O99_13505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7O99_13510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7O99_13525	COG3539	Fimbrial protein
B7O99_13530	COG3539	Fimbrial protein
B7O99_13545	COG2050	protein possibly involved in aromatic compounds catabolism
B7O99_13550	COG1024	Enoyl-CoA hydratase
B7O99_13555	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_13560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7O99_13565	COG2151	metal-sulfur cluster biosynthetic enzyme
B7O99_13570	COG3396	Phenylacetate-CoA oxygenase
B7O99_13575	COG3460	Phenylacetate-CoA oxygenase
B7O99_13580	COG3396	Phenylacetate-CoA oxygenase
B7O99_13595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B7O99_13600	COG0501	Belongs to the peptidase M48B family
B7O99_13605	COG1162	GTPase activity
B7O99_13610	COG0667	Aldo Keto reductase
B7O99_13620	COG0335	large ribosomal subunit rRNA binding
B7O99_13650	COG0175	sulfate reduction
B7O99_13660	COG4208	sulfate ABC transporter
B7O99_13680	COG0602	queuosine metabolic process
B7O99_13685	COG0720	synthase
B7O99_13690	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_13695	COG0235	Class ii aldolase
B7O99_13720	COG1566	PFAM secretion protein HlyD family protein
B7O99_13730	COG0400	carboxylic ester hydrolase activity
B7O99_13755	COG1959	2 iron, 2 sulfur cluster binding
B7O99_13760	COG1017	nitric oxide dioxygenase activity
B7O99_13760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7O99_13795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7O99_13810	COG0667	Aldo Keto reductase
B7O99_13820	COG5265	(ABC) transporter
B7O99_13855	COG3468	outer membrane autotransporter barrel domain protein
B7O99_13860	COG3468	outer membrane autotransporter barrel domain protein
B7O99_13875	COG5002	protein histidine kinase activity
B7O99_13875	COG3447	MASE1 domain protein
B7O99_13875	COG5001	Diguanylate cyclase
B7O99_13880	COG0840	transmembrane signaling receptor activity
B7O99_13885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B7O99_13890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7O99_13920	COG0583	DNA-binding transcription factor activity
B7O99_13930	COG2814	Major facilitator Superfamily
B7O99_13945	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7O99_13960	COG2084	Dehydrogenase
B7O99_13965	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_13975	COG1253	flavin adenine dinucleotide binding
B7O99_13990	COG2988	succinylglutamate desuccinylase activity
B7O99_14015	COG0861	Integral membrane protein TerC family
B7O99_14025	COG1595	DNA-templated transcription, initiation
B7O99_14055	COG3189	MarR family transcriptional regulator
B7O99_14085	COG0028	Belongs to the TPP enzyme family
B7O99_14095	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_14100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7O99_14110	COG1126	abc transporter atp-binding protein
B7O99_14135	COG0084	hydrolase, TatD family'
B7O99_14140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7O99_14145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7O99_14150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7O99_14175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B7O99_14180	COG1960	acyl-CoA dehydrogenase activity
B7O99_14190	COG2867	negative regulation of translational initiation
B7O99_14205	COG0330	HflC and HflK could
B7O99_14225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B7O99_14230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7O99_14235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7O99_14240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7O99_14260	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B7O99_14265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7O99_14270	COG0750	zinc metalloprotease
B7O99_14285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7O99_14290	COG0233	cytoplasmic translational termination
B7O99_14305	COG0052	Belongs to the universal ribosomal protein uS2 family
B7O99_14310	COG0024	Methionine aminopeptidase
B7O99_14345	COG0285	dihydrofolate synthase activity
B7O99_14375	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7O99_14385	COG1677	Flagellar hook-basal body complex protein FliE
B7O99_14395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7O99_14400	COG1317	bacterial-type flagellum organization
B7O99_14405	COG1157	protein secretion by the type III secretion system
B7O99_14420	COG1580	Controls the rotational direction of flagella during chemotaxis
B7O99_14440	COG1338	Plays a role in the flagellum-specific transport system
B7O99_14460	COG0840	transmembrane signaling receptor activity
B7O99_14470	COG1256	bacterial-type flagellum assembly
B7O99_14480	COG1706	bacterial-type flagellum-dependent cell motility
B7O99_14500	COG1749	Flagellar hook protein flgE
B7O99_14505	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B7O99_14510	COG1558	bacterial-type flagellum-dependent cell motility
B7O99_14515	COG1815	bacterial-type flagellum-dependent cell motility
B7O99_14550	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B7O99_14555	COG0745	RESPONSE REGULATOR receiver
B7O99_14565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7O99_14570	COG0840	transmembrane signaling receptor activity
B7O99_14575	COG0835	chemotaxis
B7O99_14580	COG0643	Histidine kinase
B7O99_14580	COG2198	Histidine kinase
B7O99_14615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7O99_14620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7O99_14625	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7O99_14630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B7O99_14640	COG4566	intracellular signal transduction
B7O99_14650	COG0339	signal peptide processing
B7O99_14655	COG1999	signal sequence binding
B7O99_14665	COG1538	Outer membrane efflux protein
B7O99_14675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7O99_14685	COG1187	pseudouridine synthase activity
B7O99_14690	COG3161	chorismate lyase activity
B7O99_14700	COG4681	YaeQ
B7O99_14705	COG1280	lysine exporter protein (LysE YggA)
B7O99_14720	COG0601	transmembrane transport
B7O99_14725	COG0747	negative chemotaxis
B7O99_14770	COG0668	transmembrane transport
B7O99_14775	COG0165	Argininosuccinate lyase
B7O99_14785	COG0789	Transcriptional regulator
B7O99_14795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_14805	COG1126	abc transporter atp-binding protein
B7O99_14815	COG2346	COG2346, Truncated hemoglobins
B7O99_14875	COG1335	isochorismatase
B7O99_14900	COG2837	iron assimilation
B7O99_14930	COG4691	Plasmid stability protein
B7O99_14965	COG0583	DNA-binding transcription factor activity
B7O99_14970	COG2814	Major facilitator Superfamily
B7O99_14980	COG0501	Belongs to the peptidase M48B family
B7O99_14990	COG0583	DNA-binding transcription factor activity
B7O99_15000	COG2188	Transcriptional regulator
B7O99_15015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7O99_15025	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_15030	COG0129	dihydroxy-acid dehydratase activity
B7O99_15045	COG0129	dihydroxy-acid dehydratase activity
B7O99_15055	COG3622	Belongs to the hyi family
B7O99_15060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7O99_15065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_15080	COG0583	DNA-binding transcription factor activity
B7O99_15085	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_15090	COG3246	L-lysine catabolic process to acetate
B7O99_15125	COG0697	spore germination
B7O99_15140	COG0625	glutathione transferase activity
B7O99_15160	COG1280	lysine exporter protein (LysE YggA)
B7O99_15165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7O99_15200	COG2207	Transcriptional regulator
B7O99_15240	COG1132	(ABC) transporter
B7O99_15265	COG0659	secondary active sulfate transmembrane transporter activity
B7O99_15300	COG5507	3-demethylubiquinone-9 3-methyltransferase
B7O99_15305	COG0384	phenazine biosynthesis protein PhzF
B7O99_15310	COG0583	DNA-binding transcription factor activity
B7O99_15315	COG2733	membrane
B7O99_15330	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_15335	COG3284	Transcriptional regulator
B7O99_15340	COG0656	L-ascorbic acid biosynthetic process
B7O99_15365	COG0842	Transport permease protein
B7O99_15385	COG1802	Transcriptional regulator
B7O99_15405	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_15410	COG2188	Transcriptional regulator
B7O99_15435	COG0789	Transcriptional regulator
B7O99_15450	COG1609	Transcriptional regulator
B7O99_15455	COG4172	Belongs to the ABC transporter superfamily
B7O99_15465	COG0601	transmembrane transport
B7O99_15470	COG0747	negative chemotaxis
B7O99_15485	COG1280	lysine exporter protein (LysE YggA)
B7O99_15520	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_15525	COG2079	MmgE PrpD family protein
B7O99_15545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_15560	COG3618	amidohydrolase
B7O99_15575	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B7O99_15590	COG0625	glutathione transferase activity
B7O99_15600	COG1733	regulation of RNA biosynthetic process
B7O99_15605	COG2814	Major facilitator Superfamily
B7O99_15610	COG0477	Major facilitator Superfamily
B7O99_15630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7O99_15635	COG1061	Type III restriction enzyme res subunit
B7O99_15675	COG2197	response regulator
B7O99_15680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7O99_15700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7O99_15720	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_15740	COG3064	Membrane
B7O99_15740	COG3210	domain, Protein
B7O99_15740	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B7O99_15745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7O99_15745	COG0047	phosphoribosylformylglycinamidine synthase activity
B7O99_15750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B7O99_15770	COG0613	PHP domain protein
B7O99_15805	COG0450	alkyl hydroperoxide reductase
B7O99_15810	COG1960	acyl-CoA dehydrogenase activity
B7O99_15825	COG0123	including yeast histone deacetylase and acetoin utilization protein
B7O99_15830	COG2951	lytic endotransglycosylase activity
B7O99_15845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7O99_15850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B7O99_15855	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B7O99_15885	COG0287	Prephenate dehydrogenase
B7O99_15895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B7O99_15920	COG2814	Major facilitator Superfamily
B7O99_15990	COG0583	DNA-binding transcription factor activity
B7O99_16005	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7O99_16030	COG1053	succinate dehydrogenase
B7O99_16035	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_16040	COG2079	MmgE PrpD family protein
B7O99_16050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_16075	COG0028	Belongs to the TPP enzyme family
B7O99_16075	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
B7O99_16100	COG0778	Nitroreductase
B7O99_16105	COG2814	Major facilitator Superfamily
B7O99_16110	COG3706	GGDEF domain
B7O99_16115	COG0589	response to stress
B7O99_16125	COG2951	lytic endotransglycosylase activity
B7O99_16130	COG2833	Protein of unknown function (DUF455)
B7O99_16145	COG1132	(ABC) transporter
B7O99_16160	COG3237	CsbD-like
B7O99_16170	COG2823	Periplasmic or secreted lipoprotein
B7O99_16205	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
B7O99_16210	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_16215	COG3243	poly(R)-hydroxyalkanoic acid synthase
B7O99_16225	COG0564	pseudouridine synthase activity
B7O99_16235	COG1199	ATP-dependent helicase activity
B7O99_16240	COG2183	response to ionizing radiation
B7O99_16245	COG0180	Tryptophanyl-tRNA synthetase
B7O99_16265	COG4774	siderophore transport
B7O99_16275	COG1595	DNA-templated transcription, initiation
B7O99_16280	COG2175	clavaminate synthase activity
B7O99_16290	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_16295	COG0583	DNA-binding transcription factor activity
B7O99_16300	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_16305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B7O99_16310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7O99_16315	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7O99_16320	COG0567	Dehydrogenase, E1 component
B7O99_16330	COG1522	sequence-specific DNA binding
B7O99_16340	COG0281	malic enzyme
B7O99_16340	COG0280	phosphate acetyltransferase
B7O99_16345	COG3539	Fimbrial protein
B7O99_16360	COG0372	Belongs to the citrate synthase family
B7O99_16365	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B7O99_16370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7O99_16375	COG1053	succinate dehydrogenase
B7O99_16380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B7O99_16385	COG2009	succinate dehydrogenase
B7O99_16390	COG2188	Transcriptional regulator
B7O99_16395	COG0039	L-malate dehydrogenase activity
B7O99_16415	COG2828	Protein conserved in bacteria
B7O99_16450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7O99_16460	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B7O99_16495	COG0148	phosphopyruvate hydratase activity
B7O99_16510	COG0504	CTP synthase activity
B7O99_16530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_16540	COG0747	negative chemotaxis
B7O99_16545	COG4172	Belongs to the ABC transporter superfamily
B7O99_16550	COG1446	asparaginase
B7O99_16580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7O99_16595	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B7O99_16600	COG0697	spore germination
B7O99_16605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7O99_16615	COG3193	protein, possibly involved in utilization of glycolate and propanediol
B7O99_16620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7O99_16625	COG0791	NLP P60 protein
B7O99_16635	COG0583	DNA-binding transcription factor activity
B7O99_16650	COG0583	DNA-binding transcription factor activity
B7O99_16675	COG0670	Belongs to the BI1 family
B7O99_16680	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_16690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7O99_16700	COG1381	Involved in DNA repair and RecF pathway recombination
B7O99_16705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7O99_16710	COG0571	ribonuclease III activity
B7O99_16715	COG0681	Belongs to the peptidase S26 family
B7O99_16720	COG0481	GTPase activity
B7O99_16725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7O99_16750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7O99_16775	COG0416	fatty acid biosynthetic process
B7O99_16780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B7O99_16785	COG1399	metal-binding, possibly nucleic acid-binding protein
B7O99_16790	COG0424	maF-like protein
B7O99_16800	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7O99_16805	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B7O99_16810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7O99_16815	COG0546	phosphoglycolate phosphatase activity
B7O99_16825	COG1530	ribonuclease E activity
B7O99_16835	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B7O99_16850	COG0133	tryptophan synthase activity
B7O99_16865	COG3228	Belongs to the MtfA family
B7O99_16875	COG0251	oxidation-reduction process
B7O99_16885	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B7O99_16900	COG2878	Part of a membrane complex involved in electron transport
B7O99_16905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7O99_16910	COG0411	ABC transporter
B7O99_16925	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_16940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7O99_16945	COG0410	ABC transporter
B7O99_16950	COG0411	ABC transporter
B7O99_16965	COG1268	BioY protein
B7O99_16970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B7O99_16975	COG1122	ATPase activity
B7O99_16980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7O99_16990	COG0271	Belongs to the BolA IbaG family
B7O99_17010	COG1196	nuclear chromosome segregation
B7O99_17015	COG0477	Major facilitator Superfamily
B7O99_17020	COG1573	uracil-dna glycosylase
B7O99_17025	COG1214	PFAM Peptidase M22, glycoprotease
B7O99_17030	COG0745	RESPONSE REGULATOR receiver
B7O99_17035	COG2205	protein histidine kinase activity
B7O99_17040	COG0450	alkyl hydroperoxide reductase
B7O99_17045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7O99_17070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7O99_17075	COG0560	Phosphoserine phosphatase
B7O99_17080	COG0583	DNA-binding transcription factor activity
B7O99_17085	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_17090	COG0028	Belongs to the TPP enzyme family
B7O99_17115	COG4774	siderophore transport
B7O99_17125	COG1007	ATP synthesis coupled electron transport
B7O99_17140	COG0713	ATP synthesis coupled electron transport
B7O99_17150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7O99_17155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B7O99_17160	COG1034	ATP synthesis coupled electron transport
B7O99_17170	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B7O99_17175	COG0649	NAD binding
B7O99_17185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7O99_17190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7O99_17195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B7O99_17215	COG0671	phosphoesterase, PA-phosphatase related
B7O99_17225	COG1597	lipid kinase activity
B7O99_17230	COG0583	DNA-binding transcription factor activity
B7O99_17235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7O99_17240	COG1733	regulation of RNA biosynthetic process
B7O99_17245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7O99_17265	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B7O99_17285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_17305	COG3608	succinylglutamate desuccinylase aspartoacylase
B7O99_17310	COG0626	cystathionine gamma-synthase activity
B7O99_17315	COG0583	DNA-binding transcription factor activity
B7O99_17325	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_17330	COG0165	Argininosuccinate lyase
B7O99_17345	COG3799	methylaspartate ammonia-lyase activity
B7O99_17355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7O99_17365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7O99_17370	COG0149	triose-phosphate isomerase activity
B7O99_17390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7O99_17405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B7O99_17420	COG1183	phosphatidylcholine synthase activity
B7O99_17425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B7O99_17430	COG0440	acetolactate synthase activity
B7O99_17435	COG0028	Belongs to the TPP enzyme family
B7O99_17440	COG1289	transmembrane transporter activity
B7O99_17450	COG3022	response to hydroperoxide
B7O99_17455	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_17500	COG2814	Major facilitator Superfamily
B7O99_17520	COG3706	GGDEF domain
B7O99_17550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B7O99_17555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7O99_17565	COG1674	ftsk spoiiie
B7O99_17570	COG0492	ferredoxin-NADP+ reductase activity
B7O99_17575	COG1193	negative regulation of DNA recombination
B7O99_17585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7O99_17605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B7O99_17610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B7O99_17615	COG2205	protein histidine kinase activity
B7O99_17620	COG0745	RESPONSE REGULATOR receiver
B7O99_17655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7O99_17675	COG0612	Peptidase, M16
B7O99_17695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B7O99_17710	COG1420	regulation of RNA biosynthetic process
B7O99_17715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7O99_17720	COG0497	DNA recombination
B7O99_17730	COG0735	belongs to the Fur family
B7O99_17735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7O99_17740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B7O99_17780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B7O99_17780	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7O99_17785	COG4311	Sarcosine oxidase, delta subunit
B7O99_17790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_17800	COG0583	DNA-binding transcription factor activity
B7O99_17820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_17825	COG2030	dehydratase
B7O99_17835	COG1024	Enoyl-CoA hydratase
B7O99_17860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7O99_17885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7O99_17900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_17910	COG0405	Gamma-glutamyltransferase
B7O99_17925	COG1280	lysine exporter protein (LysE YggA)
B7O99_17955	COG0583	DNA-binding transcription factor activity
B7O99_17995	COG1414	Transcriptional regulator
B7O99_18000	COG1058	Belongs to the CinA family
B7O99_18000	COG1546	Belongs to the CinA family
B7O99_18015	COG0513	Belongs to the DEAD box helicase family
B7O99_18045	COG0429	hydrolase of the alpha beta-hydrolase fold
B7O99_18050	COG4783	chaperone-mediated protein folding
B7O99_18065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B7O99_18080	COG0006	proline dipeptidase activity
B7O99_18090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7O99_18135	COG0514	ATP-dependent DNA helicase (RecQ)
B7O99_18145	COG0745	RESPONSE REGULATOR receiver
B7O99_18160	COG1271	oxidase subunit
B7O99_18175	COG2894	cell division
B7O99_18180	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B7O99_18195	COG0488	(ABC) transporter
B7O99_18220	COG4608	Belongs to the ABC transporter superfamily
B7O99_18225	COG0444	Belongs to the ABC transporter superfamily
B7O99_18230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_18235	COG0601	transmembrane transport
B7O99_18245	COG1215	transferase activity, transferring glycosyl groups
B7O99_18260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7O99_18270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7O99_18285	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_18290	COG2188	Transcriptional regulator
B7O99_18295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7O99_18300	COG2814	Major facilitator Superfamily
B7O99_18310	COG0259	pyridoxamine-phosphate oxidase activity
B7O99_18315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7O99_18330	COG0583	DNA-binding transcription factor activity
B7O99_18335	COG1960	acyl-CoA dehydrogenase activity
B7O99_18345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_18350	COG0405	Gamma-glutamyltransferase
B7O99_18360	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_18370	COG0114	fumarate hydratase activity
B7O99_18375	COG0802	atpase or kinase
B7O99_18380	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7O99_18385	COG0586	Pfam SNARE associated Golgi protein
B7O99_18415	COG0617	tRNA 3'-terminal CCA addition
B7O99_18440	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_18445	COG2188	Transcriptional regulator
B7O99_18455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7O99_18460	COG1234	tRNA 3'-trailer cleavage
B7O99_18465	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_18475	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_18480	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_18485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7O99_18490	COG2301	Belongs to the HpcH HpaI aldolase family
B7O99_18500	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
B7O99_18510	COG1024	Enoyl-CoA hydratase
B7O99_18520	COG2188	Transcriptional regulator
B7O99_18525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B7O99_18530	COG0066	3-isopropylmalate dehydratase activity
B7O99_18545	COG0752	glycyl-tRNA synthetase alpha subunit
B7O99_18550	COG0751	glycine-tRNA ligase activity
B7O99_18555	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B7O99_18560	COG0204	Acyl-transferase
B7O99_18575	COG0242	peptide deformylase activity
B7O99_18580	COG1960	acyl-CoA dehydrogenase activity
B7O99_18585	COG0700	Nucleoside recognition
B7O99_18590	COG0469	pyruvate kinase activity
B7O99_18605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7O99_18620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7O99_18630	COG2154	pterin-4-alpha-carbinolamine dehydratase
B7O99_18650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7O99_18655	COG0154	amidase activity
B7O99_18665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_18675	COG0747	negative chemotaxis
B7O99_18690	COG0019	diaminopimelate decarboxylase activity
B7O99_18705	COG3712	iron ion homeostasis
B7O99_18710	COG4774	siderophore transport
B7O99_18715	COG2353	YceI-like domain
B7O99_18720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7O99_18735	COG0583	DNA-binding transcription factor activity
B7O99_18755	COG3384	dioxygenase
B7O99_18760	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7O99_18795	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_18800	COG1309	transcriptional regulator
B7O99_18805	COG2982	Protein involved in outer membrane biogenesis
B7O99_18810	COG2818	Glycosylase
B7O99_18830	COG1653	transport
B7O99_18835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7O99_18840	COG3842	ATPase activity
B7O99_18845	COG0395	ABC-type sugar transport system, permease component
B7O99_18870	COG2186	Transcriptional regulator
B7O99_18890	COG1454	alcohol dehydrogenase
B7O99_18905	COG2011	ABC-type metal ion transport system permease component
B7O99_18910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7O99_18915	COG1501	Belongs to the glycosyl hydrolase 31 family
B7O99_18930	COG0318	PFAM AMP-dependent synthetase and ligase
B7O99_18935	COG1473	amidohydrolase
B7O99_18945	COG2855	membrane
B7O99_18950	COG1607	acyl-coa hydrolase
B7O99_18955	COG2239	Acts as a magnesium transporter
B7O99_18970	COG1522	sequence-specific DNA binding
B7O99_18975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_18980	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_19005	COG0739	heme binding
B7O99_19015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B7O99_19020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7O99_19030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7O99_19040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7O99_19060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7O99_19065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7O99_19075	COG3116	cell division
B7O99_19080	COG0275	rRNA processing
B7O99_19085	COG2001	Belongs to the MraZ family
B7O99_19100	COG0418	dihydroorotase activity
B7O99_19105	COG1473	amidohydrolase
B7O99_19145	COG1522	sequence-specific DNA binding
B7O99_19155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7O99_19160	COG4654	Cytochrome c, class I
B7O99_19215	COG2084	Dehydrogenase
B7O99_19260	COG0824	Thioesterase
B7O99_19265	COG0811	peptide transport
B7O99_19270	COG0848	biopolymer transport protein
B7O99_19295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7O99_19300	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B7O99_19305	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_19315	COG1846	Transcriptional regulator
B7O99_19320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7O99_19345	COG0183	Belongs to the thiolase family
B7O99_19355	COG1960	acyl-CoA dehydrogenase activity
B7O99_19360	COG0583	DNA-binding transcription factor activity
B7O99_19365	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_19370	COG1024	Enoyl-CoA hydratase
B7O99_19380	COG1253	flavin adenine dinucleotide binding
B7O99_19385	COG1285	pathogenesis
B7O99_19410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7O99_19415	COG0697	spore germination
B7O99_19425	COG1073	alpha beta
B7O99_19450	COG0463	Glycosyl transferase, family 2
B7O99_19460	COG0786	glutamate:sodium symporter activity
B7O99_19470	COG2031	fatty acid transporter
B7O99_19485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7O99_19490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7O99_19500	COG0328	RNA-DNA hybrid ribonuclease activity
B7O99_19505	COG2226	methyltransferase
B7O99_19515	COG0741	lytic transglycosylase activity
B7O99_19515	COG1388	LysM domain
B7O99_19530	COG2979	Protein of unknown function (DUF533)
B7O99_19550	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_19565	COG3119	arylsulfatase activity
B7O99_19590	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B7O99_19610	COG0832	Belongs to the urease beta subunit family
B7O99_19620	COG0831	urea catabolic process
B7O99_19625	COG0829	nickel cation binding
B7O99_19635	COG0633	Ferredoxin
B7O99_19650	COG2188	Transcriptional regulator
B7O99_19655	COG3799	methylaspartate ammonia-lyase activity
B7O99_19675	COG2719	SpoVR family
B7O99_19680	COG2718	Belongs to the UPF0229 family
B7O99_19685	COG2766	serine protein kinase
B7O99_19690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7O99_19690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7O99_19700	COG4977	sequence-specific DNA binding
B7O99_19705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B7O99_19730	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B7O99_19735	COG0316	Belongs to the HesB IscA family
B7O99_19745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B7O99_19755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B7O99_19760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B7O99_19765	COG0312	modulator of DNA gyrase
B7O99_19785	COG1116	anion transmembrane transporter activity
B7O99_19790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_19795	COG1335	isochorismatase
B7O99_19800	COG0346	lactoylglutathione lyase activity
B7O99_19805	COG0513	Belongs to the DEAD box helicase family
B7O99_19815	COG1802	Transcriptional regulator
B7O99_19820	COG0045	succinate-CoA ligase (ADP-forming) activity
B7O99_19820	COG1042	CoA-binding domain protein
B7O99_19820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7O99_19840	COG1522	sequence-specific DNA binding
B7O99_19870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7O99_19875	COG1696	Membrane protein involved in D-alanine export
B7O99_19915	COG0439	Biotin carboxylase
B7O99_19920	COG0511	ligase activity, forming carbon-carbon bonds
B7O99_19925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B7O99_19930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7O99_19935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7O99_19940	COG3150	esterase
B7O99_19945	COG0557	exoribonuclease II activity
B7O99_19960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7O99_19970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7O99_19990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7O99_19995	COG1678	Uncharacterized ACR, COG1678
B7O99_20040	COG1960	acyl-CoA dehydrogenase activity
B7O99_20050	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_20060	COG0410	ABC transporter
B7O99_20065	COG0411	ABC transporter
B7O99_20100	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7O99_20110	COG0494	nUDIX hydrolase
B7O99_20115	COG1538	Outer membrane efflux protein
B7O99_20135	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
B7O99_20140	COG0237	dephospho-CoA kinase activity
B7O99_20160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B7O99_20165	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7O99_20180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7O99_20195	COG1126	abc transporter atp-binding protein
B7O99_20200	COG0765	amino acid transport
B7O99_20205	COG4597	amino acid ABC transporter
B7O99_20210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_20215	COG2884	Cell division ATP-binding protein ftsE
B7O99_20220	COG2177	Part of the ABC transporter FtsEX involved in
B7O99_20235	COG1194	a g-specific adenine glycosylase
B7O99_20255	COG4206	TonB-dependent receptor
B7O99_20260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7O99_20270	COG0351	phosphomethylpyrimidine kinase
B7O99_20275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7O99_20285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B7O99_20295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B7O99_20310	COG2226	methyltransferase
B7O99_20315	COG0745	RESPONSE REGULATOR receiver
B7O99_20320	COG5002	protein histidine kinase activity
B7O99_20330	COG5002	protein histidine kinase activity
B7O99_20340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7O99_20345	COG0583	DNA-binding transcription factor activity
B7O99_20355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B7O99_20360	COG1984	allophanate hydrolase subunit 2
B7O99_20365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B7O99_20375	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_20385	COG1024	Enoyl-CoA hydratase
B7O99_20400	COG1802	Transcriptional regulator
B7O99_20410	COG1238	metal cluster binding
B7O99_20415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7O99_20420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B7O99_20435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B7O99_20440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B7O99_20445	COG4988	ABC transporter
B7O99_20455	COG1294	oxidase, subunit
B7O99_20480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B7O99_20495	COG1137	ATPase activity
B7O99_20500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7O99_20510	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B7O99_20515	COG2010	Cytochrome c
B7O99_20515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7O99_20535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7O99_20550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B7O99_20555	COG2823	Periplasmic or secreted lipoprotein
B7O99_20585	COG0471	metal ion transport
B7O99_20590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B7O99_20595	COG0772	Belongs to the SEDS family
B7O99_20600	COG0768	penicillin binding
B7O99_20610	COG1792	Involved in formation and maintenance of cell shape
B7O99_20615	COG1077	Cell shape determining protein MreB Mrl
B7O99_20640	COG0708	Exodeoxyribonuclease III
B7O99_20650	COG2860	membrane
B7O99_20660	COG0583	DNA-binding transcription factor activity
B7O99_20665	COG0473	3-isopropylmalate dehydrogenase activity
B7O99_20690	COG0583	DNA-binding transcription factor activity
B7O99_20695	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B7O99_20700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7O99_20705	COG0765	amino acid transport
B7O99_20710	COG0765	amino acid transport
B7O99_20715	COG1126	abc transporter atp-binding protein
B7O99_20720	COG1794	racemase activity, acting on amino acids and derivatives
B7O99_20725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B7O99_20730	COG2223	nitrite transmembrane transporter activity
B7O99_20735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7O99_20735	COG2813	Specifically methylates the guanine in position
B7O99_20745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B7O99_20790	COG0583	DNA-binding transcription factor activity
B7O99_20795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B7O99_20800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B7O99_20810	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7O99_20835	COG0154	amidase activity
B7O99_20845	COG1414	Transcriptional regulator
B7O99_20855	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7O99_20855	COG1024	Enoyl-CoA hydratase
B7O99_20865	COG2132	Multicopper oxidase
B7O99_20910	COG1024	Enoyl-CoA hydratase
B7O99_20915	COG1024	Enoyl-CoA hydratase
B7O99_20920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7O99_20930	COG0747	negative chemotaxis
B7O99_20940	COG0601	transmembrane transport
B7O99_20945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_20950	COG0444	Belongs to the ABC transporter superfamily
B7O99_20955	COG4608	Belongs to the ABC transporter superfamily
B7O99_20965	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7O99_20970	COG0210	DNA helicase
B7O99_20975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7O99_20990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B7O99_20995	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B7O99_21005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B7O99_21010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7O99_21015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7O99_21025	COG0356	it plays a direct role in the translocation of protons across the membrane
B7O99_21040	COG1024	Enoyl-CoA hydratase
B7O99_21065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7O99_21070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7O99_21075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7O99_21080	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B7O99_21085	COG2967	ApaG domain
B7O99_21095	COG0546	phosphoglycolate phosphatase activity
B7O99_21105	COG0512	Glutamine amidotransferase of anthranilate synthase
B7O99_21110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7O99_21115	COG0134	indole-3-glycerol-phosphate synthase activity
B7O99_21120	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_21140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7O99_21150	COG1607	acyl-coa hydrolase
B7O99_21205	COG1802	Transcriptional regulator
B7O99_21235	COG1595	DNA-templated transcription, initiation
B7O99_21250	COG3720	iron ion transport
B7O99_21255	COG4558	Periplasmic binding protein
B7O99_21260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7O99_21270	COG1683	Conserved Protein
B7O99_21285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7O99_21300	COG3064	Membrane
B7O99_21305	COG0583	DNA-binding transcription factor activity
B7O99_21315	COG1234	tRNA 3'-trailer cleavage
B7O99_21325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7O99_21330	COG1802	Transcriptional regulator
B7O99_21340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7O99_21360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_21380	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_21385	COG0583	DNA-binding transcription factor activity
B7O99_21390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7O99_21395	COG1522	sequence-specific DNA binding
B7O99_21400	COG0183	Belongs to the thiolase family
B7O99_21460	COG2814	Major facilitator Superfamily
B7O99_21465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B7O99_21485	COG1999	signal sequence binding
B7O99_21490	COG0109	protoheme IX farnesyltransferase activity
B7O99_21530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7O99_21550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7O99_21560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7O99_21570	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B7O99_21575	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B7O99_21585	COG0070	glutamate synthase
B7O99_21585	COG0069	glutamate synthase activity
B7O99_21585	COG0067	glutamate synthase
B7O99_21595	COG3047	cAMP biosynthetic process
B7O99_21605	COG1127	ABC transporter
B7O99_21610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7O99_21615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7O99_21620	COG2853	Lipoprotein
B7O99_21630	COG1131	(ABC) transporter
B7O99_21635	COG0842	Transport permease protein
B7O99_21650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7O99_21655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7O99_21665	COG0131	Imidazoleglycerol-phosphate dehydratase
B7O99_21670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7O99_21675	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B7O99_21685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B7O99_21695	COG0537	adenosine 5'-monophosphoramidase activity
B7O99_21700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7O99_21725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7O99_21735	COG0723	plastoquinol--plastocyanin reductase activity
B7O99_21740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7O99_21745	COG2857	Cytochrome c1
B7O99_21750	COG0625	glutathione transferase activity
B7O99_21755	COG2969	positive regulation of protein catabolic process
B7O99_21785	COG0583	DNA-binding transcription factor activity
B7O99_21790	COG0492	ferredoxin-NADP+ reductase activity
B7O99_21810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_21820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7O99_21835	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_21895	COG3504	Conjugal transfer protein
B7O99_21915	COG0697	spore germination
B7O99_21935	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B7O99_21940	COG0747	negative chemotaxis
B7O99_21950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7O99_21960	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B7O99_21970	COG0513	Belongs to the DEAD box helicase family
B7O99_21975	COG1280	lysine exporter protein (LysE YggA)
B7O99_22000	COG0583	DNA-binding transcription factor activity
B7O99_22010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B7O99_22020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7O99_22025	COG0154	amidase activity
B7O99_22030	COG1609	Transcriptional regulator
B7O99_22050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B7O99_22055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7O99_22060	COG3842	ATPase activity
B7O99_22065	COG1653	transport
B7O99_22070	COG1175	transmembrane transport
B7O99_22075	COG0395	ABC-type sugar transport system, permease component
B7O99_22100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7O99_22110	COG1280	lysine exporter protein (LysE YggA)
B7O99_22125	COG1960	acyl-CoA dehydrogenase activity
B7O99_22135	COG0183	Belongs to the thiolase family
B7O99_22140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7O99_22160	COG3181	Tripartite tricarboxylate transporter family receptor
B7O99_22185	COG2922	Belongs to the Smg family
B7O99_22210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7O99_22215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_22220	COG1028	Short-chain dehydrogenase reductase Sdr
B7O99_22225	COG1012	belongs to the aldehyde dehydrogenase family
B7O99_22235	COG0028	Belongs to the TPP enzyme family
B7O99_22240	COG1522	sequence-specific DNA binding
B7O99_22245	COG3781	membrane
B7O99_22255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7O99_22275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7O99_22300	COG1304	FMN binding
B7O99_22305	COG1254	Belongs to the acylphosphatase family
B7O99_22320	COG1414	Transcriptional regulator
B7O99_22340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B7O99_22345	COG0594	ribonuclease P activity
B7O99_22350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B7O99_22360	COG0753	catalase activity
B7O99_22365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7O99_22370	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7O99_22380	COG2175	clavaminate synthase activity
B7O99_22385	COG1473	amidohydrolase
B7O99_22390	COG4608	Belongs to the ABC transporter superfamily
B7O99_22395	COG0444	Belongs to the ABC transporter superfamily
B7O99_22405	COG0601	transmembrane transport
B7O99_22410	COG0747	negative chemotaxis
B7O99_22430	COG5002	protein histidine kinase activity
B7O99_22430	COG3850	Histidine kinase
B7O99_22450	COG0436	Aminotransferase
B7O99_22455	COG1278	Cold shock