locus-tag	class	description
AV743_00005	COG0445	tRNA wobble uridine modification
AV743_00015	COG1192	Involved in chromosome partitioning
AV743_00025	COG1475	DNA binding
AV743_00030	COG0252	asparaginase activity
AV743_00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AV743_00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV743_00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AV743_00080	COG0081	regulation of translation
AV743_00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AV743_00090	COG0222	ribosome binding
AV743_00095	COG0085	RNA polymerase activity
AV743_00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AV743_00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_00165	COG1024	Enoyl-CoA hydratase
AV743_00185	COG0752	glycyl-tRNA synthetase alpha subunit
AV743_00190	COG0751	glycine-tRNA ligase activity
AV743_00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV743_00200	COG0204	Acyl-transferase
AV743_00215	COG0242	peptide deformylase activity
AV743_00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_00260	COG2813	Specifically methylates the guanine in position
AV743_00275	COG2223	nitrite transmembrane transporter activity
AV743_00280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_00285	COG1794	racemase activity, acting on amino acids and derivatives
AV743_00290	COG1126	abc transporter atp-binding protein
AV743_00295	COG0765	amino acid transport
AV743_00300	COG0765	amino acid transport
AV743_00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_00400	COG0326	Molecular chaperone. Has ATPase activity
AV743_00405	COG0625	glutathione transferase activity
AV743_00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV743_00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AV743_00435	COG0494	nUDIX hydrolase
AV743_00445	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AV743_00460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_00470	COG0747	negative chemotaxis
AV743_00475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AV743_00495	COG0697	spore germination
AV743_00510	COG2948	multi-organism process
AV743_00515	COG3504	Conjugal transfer protein
AV743_00535	COG3451	type IV secretory pathway VirB4
AV743_00575	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_00590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV743_00595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV743_00600	COG0537	adenosine 5'-monophosphoramidase activity
AV743_00610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AV743_00615	COG0107	imidazoleglycerol-phosphate synthase activity
AV743_00620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AV743_00625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AV743_00630	COG0131	Imidazoleglycerol-phosphate dehydratase
AV743_00635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV743_00640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AV743_00645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AV743_00650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AV743_00660	COG0842	Transport permease protein
AV743_00675	COG2853	Lipoprotein
AV743_00680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV743_00685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV743_00690	COG1127	ABC transporter
AV743_00700	COG3047	cAMP biosynthetic process
AV743_00710	COG0067	glutamate synthase
AV743_00710	COG0070	glutamate synthase
AV743_00710	COG0069	glutamate synthase activity
AV743_00720	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AV743_00725	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AV743_00735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV743_00740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AV743_00760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV743_00800	COG0109	protoheme IX farnesyltransferase activity
AV743_00805	COG1999	signal sequence binding
AV743_00825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AV743_00830	COG2814	Major facilitator Superfamily
AV743_00875	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_00920	COG2816	NAD+ diphosphatase activity
AV743_00925	COG1309	transcriptional regulator
AV743_00930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_00945	COG1024	Enoyl-CoA hydratase
AV743_00960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_00975	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_01005	COG0438	transferase activity, transferring glycosyl groups
AV743_01010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AV743_01015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AV743_01045	COG0859	PFAM glycosyl transferase family 9
AV743_01060	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AV743_01070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV743_01075	COG1127	ABC transporter
AV743_01100	COG1686	Belongs to the peptidase S11 family
AV743_01110	COG2921	Belongs to the UPF0250 family
AV743_01115	COG0321	lipoyl(octanoyl) transferase activity
AV743_01120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AV743_01155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV743_01165	COG0018	arginyl-trna synthetase
AV743_01190	COG1175	transmembrane transport
AV743_01195	COG1653	transport
AV743_01200	COG3842	ATPase activity
AV743_01205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AV743_01215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AV743_01235	COG1609	Transcriptional regulator
AV743_01245	COG0154	amidase activity
AV743_01250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV743_01260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AV743_01270	COG0583	DNA-binding transcription factor activity
AV743_01290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AV743_01305	COG1802	Transcriptional regulator
AV743_01320	COG1024	Enoyl-CoA hydratase
AV743_01335	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_01350	COG1984	allophanate hydrolase subunit 2
AV743_01355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AV743_01365	COG0583	DNA-binding transcription factor activity
AV743_01370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV743_01380	COG5002	protein histidine kinase activity
AV743_01390	COG5002	protein histidine kinase activity
AV743_01395	COG0745	RESPONSE REGULATOR receiver
AV743_01400	COG2226	methyltransferase
AV743_01415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV743_01435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AV743_01445	COG0513	Belongs to the DEAD box helicase family
AV743_01450	COG1280	lysine exporter protein (LysE YggA)
AV743_01455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AV743_01505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV743_01505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV743_01515	COG0489	protein tyrosine kinase activity
AV743_01530	COG0717	Belongs to the dCTP deaminase family
AV743_01555	COG1982	Orn Lys Arg decarboxylase major
AV743_01560	COG2081	HI0933 family
AV743_01570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AV743_01580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AV743_01585	COG0509	glycine decarboxylation via glycine cleavage system
AV743_01590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AV743_01590	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AV743_01655	COG1304	FMN binding
AV743_01670	COG0154	amidase activity
AV743_01675	COG1414	Transcriptional regulator
AV743_01695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AV743_01700	COG0594	ribonuclease P activity
AV743_01705	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AV743_01710	COG0706	membrane insertase activity
AV743_01745	COG0582	viral genome integration into host DNA
AV743_01780	COG3723	Recombinational DNA repair protein, rece pathway
AV743_01850	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_01860	COG0411	ABC transporter
AV743_01865	COG0410	ABC transporter
AV743_01880	COG1024	Enoyl-CoA hydratase
AV743_01885	COG1960	acyl-CoA dehydrogenase activity
AV743_01910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AV743_01930	COG1678	Uncharacterized ACR, COG1678
AV743_01935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AV743_01940	COG0540	Belongs to the ATCase OTCase family
AV743_01955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV743_01965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV743_02000	COG1234	tRNA 3'-trailer cleavage
AV743_02020	COG3064	Membrane
AV743_02035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV743_02050	COG1683	Conserved Protein
AV743_02055	COG1120	ATPase activity
AV743_02060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV743_02065	COG4558	Periplasmic binding protein
AV743_02070	COG3720	iron ion transport
AV743_02080	COG3712	iron ion homeostasis
AV743_02085	COG1595	DNA-templated transcription, initiation
AV743_02110	COG2423	ornithine cyclodeaminase activity
AV743_02120	COG1802	Transcriptional regulator
AV743_02130	COG3069	C4-dicarboxylate transmembrane transporter activity
AV743_02140	COG1012	belongs to the aldehyde dehydrogenase family
AV743_02180	COG2860	membrane
AV743_02185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV743_02190	COG0708	Exodeoxyribonuclease III
AV743_02195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AV743_02200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AV743_02205	COG0154	amidase activity
AV743_02210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AV743_02215	COG1077	Cell shape determining protein MreB Mrl
AV743_02220	COG1792	Involved in formation and maintenance of cell shape
AV743_02230	COG0768	penicillin binding
AV743_02235	COG0772	Belongs to the SEDS family
AV743_02240	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AV743_02245	COG0471	metal ion transport
AV743_02250	COG1309	transcriptional regulator
AV743_02260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV743_02275	COG2823	Periplasmic or secreted lipoprotein
AV743_02280	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AV743_02295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV743_02315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_02325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_02345	COG0492	ferredoxin-NADP+ reductase activity
AV743_02355	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_02360	COG1024	Enoyl-CoA hydratase
AV743_02360	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_02365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_02370	COG0028	Belongs to the TPP enzyme family
AV743_02395	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_02405	COG0697	spore germination
AV743_02435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV743_02440	COG0463	Glycosyl transferase, family 2
AV743_02455	COG0786	glutamate:sodium symporter activity
AV743_02465	COG2031	fatty acid transporter
AV743_02480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV743_02495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV743_02510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_02520	COG1285	pathogenesis
AV743_02525	COG1253	flavin adenine dinucleotide binding
AV743_02530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_02535	COG1024	Enoyl-CoA hydratase
AV743_02540	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_02545	COG0583	DNA-binding transcription factor activity
AV743_02550	COG1960	acyl-CoA dehydrogenase activity
AV743_02580	COG0583	DNA-binding transcription factor activity
AV743_02585	COG1278	Cold shock
AV743_02595	COG1802	Transcriptional regulator
AV743_02600	COG1012	belongs to the aldehyde dehydrogenase family
AV743_02605	COG2031	fatty acid transporter
AV743_02610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV743_02610	COG1017	nitric oxide dioxygenase activity
AV743_02615	COG0251	oxidation-reduction process
AV743_02635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_02645	COG0583	DNA-binding transcription factor activity
AV743_02650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_02665	COG0028	Belongs to the TPP enzyme family
AV743_02675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AV743_02685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_02695	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_02705	COG1802	Transcriptional regulator
AV743_02715	COG1802	Transcriptional regulator
AV743_02725	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_02745	COG1126	abc transporter atp-binding protein
AV743_02750	COG0765	amino acid transport
AV743_02770	COG1538	Outer membrane efflux protein
AV743_02775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV743_02780	COG2274	protein secretion by the type I secretion system
AV743_02785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AV743_02795	COG2994	toxin metabolic process
AV743_02810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_02815	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AV743_02825	COG0583	DNA-binding transcription factor activity
AV743_02835	COG0142	geranyltranstransferase activity
AV743_02845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AV743_02850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AV743_02855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AV743_02860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV743_02905	COG3712	iron ion homeostasis
AV743_02910	COG4774	siderophore transport
AV743_02915	COG2353	YceI-like domain
AV743_02930	COG0019	diaminopimelate decarboxylase activity
AV743_02955	COG0601	transmembrane transport
AV743_02960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_02970	COG0154	amidase activity
AV743_02975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AV743_03000	COG2154	pterin-4-alpha-carbinolamine dehydratase
AV743_03010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AV743_03020	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AV743_03025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV743_03030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AV743_03035	COG1929	Belongs to the glycerate kinase type-1 family
AV743_03040	COG0469	pyruvate kinase activity
AV743_03045	COG0700	Nucleoside recognition
AV743_03100	COG1024	Enoyl-CoA hydratase
AV743_03105	COG1024	Enoyl-CoA hydratase
AV743_03110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AV743_03130	COG0601	transmembrane transport
AV743_03135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_03140	COG4172	Belongs to the ABC transporter superfamily
AV743_03150	COG2195	Cleaves the N-terminal amino acid of tripeptides
AV743_03160	COG0210	DNA helicase
AV743_03165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AV743_03170	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AV743_03180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AV743_03185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AV743_03190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AV743_03195	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AV743_03200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AV743_03205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AV743_03215	COG0356	it plays a direct role in the translocation of protons across the membrane
AV743_03240	COG1024	Enoyl-CoA hydratase
AV743_03245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV743_03250	COG3634	alkyl hydroperoxide reductase activity
AV743_03260	COG0037	tRNA processing
AV743_03270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV743_03275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV743_03280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV743_03285	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AV743_03290	COG2967	ApaG domain
AV743_03300	COG0546	phosphoglycolate phosphatase activity
AV743_03310	COG0512	Glutamine amidotransferase of anthranilate synthase
AV743_03315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV743_03320	COG0134	indole-3-glycerol-phosphate synthase activity
AV743_03345	COG0583	DNA-binding transcription factor activity
AV743_03360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV743_03365	COG0259	pyridoxamine-phosphate oxidase activity
AV743_03375	COG2814	Major facilitator Superfamily
AV743_03380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AV743_03385	COG2188	Transcriptional regulator
AV743_03390	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_03410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AV743_03420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AV743_03435	COG1215	transferase activity, transferring glycosyl groups
AV743_03445	COG0601	transmembrane transport
AV743_03480	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AV743_03485	COG2894	cell division
AV743_03490	COG0850	regulation of cytokinetic process
AV743_03495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV743_03500	COG1271	oxidase subunit
AV743_03515	COG0745	RESPONSE REGULATOR receiver
AV743_03535	COG2979	Protein of unknown function (DUF533)
AV743_03555	COG1388	LysM domain
AV743_03555	COG0741	lytic transglycosylase activity
AV743_03565	COG2226	methyltransferase
AV743_03570	COG0328	RNA-DNA hybrid ribonuclease activity
AV743_03645	COG0411	ABC transporter
AV743_03665	COG1960	acyl-CoA dehydrogenase activity
AV743_03680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_03700	COG2718	Belongs to the UPF0229 family
AV743_03705	COG2719	SpoVR family
AV743_03730	COG2188	Transcriptional regulator
AV743_03755	COG0829	nickel cation binding
AV743_03760	COG0831	urea catabolic process
AV743_03770	COG0832	Belongs to the urease beta subunit family
AV743_03775	COG0804	urea catabolic process
AV743_03785	COG0830	nickel cation binding
AV743_03790	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AV743_03810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_03830	COG0747	negative chemotaxis
AV743_03845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_03855	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AV743_03865	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AV743_03870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV743_03875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AV743_03890	COG0438	transferase activity, transferring glycosyl groups
AV743_03905	COG0438	transferase activity, transferring glycosyl groups
AV743_03910	COG0438	transferase activity, transferring glycosyl groups
AV743_03915	COG0166	Belongs to the GPI family
AV743_03930	COG0277	FAD linked oxidase domain protein
AV743_03935	COG0745	RESPONSE REGULATOR receiver
AV743_03940	COG0642	Histidine kinase
AV743_03945	COG1368	sulfuric ester hydrolase activity
AV743_03955	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AV743_03980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AV743_03990	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AV743_03995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AV743_04005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AV743_04010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AV743_04015	COG0193	aminoacyl-tRNA hydrolase activity
AV743_04025	COG0012	GTP binding
AV743_04030	COG0582	viral genome integration into host DNA
AV743_04055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AV743_04110	COG0745	RESPONSE REGULATOR receiver
AV743_04125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_04130	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AV743_04185	COG2096	Adenosyltransferase
AV743_04200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AV743_04205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AV743_04210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AV743_04215	COG0523	cobalamin synthesis protein
AV743_04220	COG0735	belongs to the Fur family
AV743_04230	COG1121	(ABC) transporter
AV743_04240	COG0803	Belongs to the bacterial solute-binding protein 9 family
AV743_04250	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AV743_04260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AV743_04270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AV743_04275	COG1560	Kdo2-lipid A biosynthetic process
AV743_04285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AV743_04300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AV743_04305	COG1950	PFAM Membrane protein of
AV743_04325	COG0583	DNA-binding transcription factor activity
AV743_04335	COG0477	Major facilitator Superfamily
AV743_04350	COG0617	tRNA 3'-terminal CCA addition
AV743_04360	COG0513	Belongs to the DEAD box helicase family
AV743_04365	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AV743_04385	COG2084	Dehydrogenase
AV743_04420	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AV743_04425	COG0129	dihydroxy-acid dehydratase activity
AV743_04430	COG4654	Cytochrome c, class I
AV743_04435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV743_04445	COG1522	sequence-specific DNA binding
AV743_04485	COG1473	amidohydrolase
AV743_04490	COG0418	dihydroorotase activity
AV743_04505	COG2001	Belongs to the MraZ family
AV743_04510	COG0275	rRNA processing
AV743_04515	COG3116	cell division
AV743_04525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV743_04530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV743_04535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AV743_04545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AV743_04550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV743_04555	COG1181	Belongs to the D-alanine--D-alanine ligase family
AV743_04560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AV743_04570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AV743_04575	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AV743_04585	COG0739	heme binding
AV743_04590	COG0653	protein targeting
AV743_04615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_04620	COG1522	sequence-specific DNA binding
AV743_04645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AV743_04655	COG0557	exoribonuclease II activity
AV743_04660	COG3150	esterase
AV743_04665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV743_04670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV743_04675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AV743_04680	COG0511	ligase activity, forming carbon-carbon bonds
AV743_04685	COG0439	Biotin carboxylase
AV743_04725	COG1696	Membrane protein involved in D-alanine export
AV743_04730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV743_04765	COG1522	sequence-specific DNA binding
AV743_04780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV743_04785	COG0045	succinate-CoA ligase (ADP-forming) activity
AV743_04785	COG1042	CoA-binding domain protein
AV743_04785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV743_04800	COG1802	Transcriptional regulator
AV743_04805	COG3069	C4-dicarboxylate transmembrane transporter activity
AV743_04810	COG0513	Belongs to the DEAD box helicase family
AV743_04815	COG0346	lactoylglutathione lyase activity
AV743_04820	COG1335	isochorismatase
AV743_04825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_04830	COG1116	anion transmembrane transporter activity
AV743_04845	COG3028	Belongs to the UPF0307 family
AV743_04850	COG0312	modulator of DNA gyrase
AV743_04855	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_04860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AV743_04865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV743_04870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AV743_04880	COG0316	Belongs to the HesB IscA family
AV743_04885	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AV743_04900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AV743_04910	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AV743_04915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AV743_04930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV743_04930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV743_04965	COG0583	DNA-binding transcription factor activity
AV743_05005	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AV743_05015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV743_05020	COG1845	cytochrome c oxidase, subunit III
AV743_05025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AV743_05030	COG0640	Transcriptional regulator
AV743_05050	COG3220	belongs to the UPF0276 family
AV743_05125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV743_05130	COG0312	modulator of DNA gyrase
AV743_05135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AV743_05140	COG3064	Membrane
AV743_05140	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AV743_05140	COG3210	domain, Protein
AV743_05140	COG3064	Membrane
AV743_05140	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AV743_05140	COG3210	domain, Protein
AV743_05145	COG0277	FAD linked oxidase domain protein
AV743_05150	COG0277	FAD linked oxidase domain protein
AV743_05155	COG0277	FAD linked oxidase domain protein
AV743_05160	COG0247	lactate metabolic process
AV743_05165	COG2819	hydrolase of the alpha beta superfamily
AV743_05180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AV743_05185	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV743_05195	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV743_05210	COG0583	DNA-binding transcription factor activity
AV743_05215	COG0482	sulfurtransferase activity
AV743_05220	COG0730	response to heat
AV743_05225	COG0625	glutathione transferase activity
AV743_05230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AV743_05235	COG3909	cytochrome
AV743_05275	COG0154	amidase activity
AV743_05280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_05285	COG1024	Enoyl-CoA hydratase
AV743_05300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_05315	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_05320	COG1414	Transcriptional regulator
AV743_05330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_05335	COG0251	oxidation-reduction process
AV743_05340	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_05355	COG0410	ABC transporter
AV743_05375	COG0583	DNA-binding transcription factor activity
AV743_05385	COG0590	tRNA wobble adenosine to inosine editing
AV743_05390	COG2807	transmembrane transport
AV743_05410	COG0154	amidase activity
AV743_05415	COG0307	riboflavin synthase, alpha
AV743_05420	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_05425	COG1522	sequence-specific DNA binding
AV743_05435	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_05445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_05465	COG1063	alcohol dehydrogenase
AV743_05490	COG1418	mRNA catabolic process
AV743_05495	COG1448	Aminotransferase
AV743_05500	COG0583	DNA-binding transcription factor activity
AV743_05510	COG0477	Major facilitator Superfamily
AV743_05515	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_05530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_05535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AV743_05540	COG0583	DNA-binding transcription factor activity
AV743_05600	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_05605	COG1309	transcriptional regulator
AV743_05610	COG2982	Protein involved in outer membrane biogenesis
AV743_05615	COG2818	Glycosylase
AV743_05635	COG1653	transport
AV743_05650	COG3842	ATPase activity
AV743_05655	COG0395	ABC-type sugar transport system, permease component
AV743_05660	COG1175	transmembrane transport
AV743_05675	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_05680	COG2186	Transcriptional regulator
AV743_05710	COG1454	alcohol dehydrogenase
AV743_05730	COG2011	ABC-type metal ion transport system permease component
AV743_05735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AV743_05740	COG1501	Belongs to the glycosyl hydrolase 31 family
AV743_05765	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_05770	COG1473	amidohydrolase
AV743_05780	COG2855	membrane
AV743_05785	COG1607	acyl-coa hydrolase
AV743_05790	COG2239	Acts as a magnesium transporter
AV743_05810	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_05820	COG1722	exodeoxyribonuclease VII activity
AV743_05825	COG0142	geranyltranstransferase activity
AV743_05830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AV743_05835	COG1469	GTP cyclohydrolase I activity
AV743_05840	COG0360	Binds together with S18 to 16S ribosomal RNA
AV743_05845	COG2965	DNA replication, synthesis of RNA primer
AV743_05850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AV743_05855	COG0359	binds to the 23S rRNA
AV743_05865	COG0305	Participates in initiation and elongation during chromosome replication
AV743_05875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AV743_05880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AV743_05885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AV743_05890	COG3737	Protein of unknown function (DUF498/DUF598)
AV743_05895	COG0436	Aminotransferase
AV743_05920	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AV743_05950	COG0268	Binds directly to 16S ribosomal RNA
AV743_05960	COG0728	peptidoglycan biosynthetic process
AV743_05970	COG0563	adenylate kinase activity
AV743_05975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AV743_05980	COG2835	tetraacyldisaccharide 4'-kinase activity
AV743_05985	COG1663	tetraacyldisaccharide 4'-kinase activity
AV743_05990	COG0848	biopolymer transport protein
AV743_05995	COG0811	peptide transport
AV743_06005	COG1570	exodeoxyribonuclease VII activity
AV743_06010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AV743_06015	COG0038	chloride channel
AV743_06020	COG0183	Belongs to the thiolase family
AV743_06030	COG1278	Cold shock
AV743_06035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AV743_06045	COG4953	penicillin-binding protein 1C
AV743_06050	COG0542	response to heat
AV743_06055	COG2995	paraquat-inducible protein a
AV743_06060	COG3008	intermembrane lipid transfer
AV743_06060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV743_06070	COG0506	proline dehydrogenase activity
AV743_06070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AV743_06070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AV743_06085	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_06105	COG2271	Major facilitator Superfamily
AV743_06110	COG1309	transcriptional regulator
AV743_06120	COG3468	outer membrane autotransporter barrel domain protein
AV743_06155	COG0477	Major facilitator Superfamily
AV743_06165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV743_06170	COG1845	cytochrome c oxidase, subunit III
AV743_06175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AV743_06185	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_06205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AV743_06210	COG0303	'Molybdopterin
AV743_06215	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV743_06230	COG0315	cyclic pyranopterin monophosphate synthase activity
AV743_06240	COG0412	Dienelactone hydrolase
AV743_06250	COG0678	peroxiredoxin activity
AV743_06260	COG0697	spore germination
AV743_06265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AV743_06290	COG0789	Transcriptional regulator
AV743_06305	COG3468	outer membrane autotransporter barrel domain protein
AV743_06315	COG5441	Belongs to the UPF0261 family
AV743_06320	COG5564	TIM-barrel signal transduction protein
AV743_06335	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AV743_06350	COG1477	protein flavinylation
AV743_06370	COG1131	(ABC) transporter
AV743_06375	COG0842	Transport permease protein
AV743_06385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AV743_06390	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AV743_06390	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AV743_06395	COG1562	ergosterol biosynthetic process
AV743_06400	COG1562	ergosterol biosynthetic process
AV743_06405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AV743_06410	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_06430	COG2304	oxidoreductase activity
AV743_06450	COG0534	Mate efflux family protein
AV743_06460	COG0254	rRNA binding
AV743_06465	COG3483	tryptophan 2,3-dioxygenase activity
AV743_06470	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AV743_06475	COG2003	Belongs to the UPF0758 family
AV743_06480	COG1047	Peptidyl-prolyl cis-trans
AV743_06490	COG0625	glutathione transferase activity
AV743_06510	COG0523	cobalamin synthesis protein
AV743_06520	COG0583	DNA-binding transcription factor activity
AV743_06530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AV743_06535	COG1187	pseudouridine synthase activity
AV743_06540	COG0779	Required for maturation of 30S ribosomal subunits
AV743_06545	COG2251	uridine kinase activity
AV743_06545	COG0195	Participates in both transcription termination and antitermination
AV743_06550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AV743_06555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AV743_06560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AV743_06580	COG1611	Belongs to the LOG family
AV743_06595	COG0412	Dienelactone hydrolase
AV743_06600	COG1283	sodium-dependent phosphate transmembrane transporter activity
AV743_06605	COG1760	l-serine dehydratase
AV743_06610	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AV743_06615	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AV743_06625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AV743_06635	COG0187	DNA topoisomerase II activity
AV743_06650	COG2311	Membrane
AV743_06670	COG3842	ATPase activity
AV743_06675	COG0395	ABC-type sugar transport system, permease component
AV743_06680	COG1175	transmembrane transport
AV743_06685	COG1653	transport
AV743_06695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AV743_06710	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_06725	COG0410	ABC transporter
AV743_06730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AV743_06760	COG2363	Small membrane protein
AV743_06800	COG0095	Lipoate-protein ligase
AV743_06815	COG0625	glutathione transferase activity
AV743_06820	COG0386	Belongs to the glutathione peroxidase family
AV743_06840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_06870	COG2259	Doxx family
AV743_06885	COG0667	Aldo Keto reductase
AV743_06915	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AV743_06935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV743_06945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV743_06995	COG0210	DNA helicase
AV743_07000	COG0598	Magnesium transport protein CorA
AV743_07010	COG0747	negative chemotaxis
AV743_07015	COG0601	transmembrane transport
AV743_07020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_07025	COG4172	Belongs to the ABC transporter superfamily
AV743_07030	COG1846	Transcriptional regulator
AV743_07075	COG4964	Belongs to the GSP D family
AV743_07115	COG2204	response regulator
AV743_07130	COG1595	DNA-templated transcription, initiation
AV743_07140	COG3474	cytochrome
AV743_07145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV743_07160	COG3384	dioxygenase
AV743_07165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AV743_07190	COG2885	chlorophyll binding
AV743_07225	COG0697	spore germination
AV743_07230	COG0730	response to heat
AV743_07250	COG0583	DNA-binding transcription factor activity
AV743_07255	COG0427	acetyl-CoA hydrolase
AV743_07300	COG3468	outer membrane autotransporter barrel domain protein
AV743_07305	COG0424	maF-like protein
AV743_07310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AV743_07315	COG0799	negative regulation of ribosome biogenesis
AV743_07320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AV743_07325	COG0408	coproporphyrinogen oxidase activity
AV743_07330	COG0151	Belongs to the GarS family
AV743_07335	COG0217	transcriptional regulatory protein
AV743_07340	COG0433	COG0433 Predicted ATPase
AV743_07345	COG1115	amino acid carrier protein
AV743_07350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AV743_07360	COG1012	belongs to the aldehyde dehydrogenase family
AV743_07385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AV743_07400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_07410	COG0747	negative chemotaxis
AV743_07420	COG0473	3-isopropylmalate dehydrogenase activity
AV743_07425	COG2814	Major facilitator Superfamily
AV743_07430	COG1566	PFAM secretion protein HlyD family protein
AV743_07440	COG1846	Transcriptional regulator
AV743_07450	COG0697	spore germination
AV743_07460	COG0501	Belongs to the peptidase M48B family
AV743_07480	COG0583	DNA-binding transcription factor activity
AV743_07485	COG3842	ATPase activity
AV743_07490	COG1178	ABC-type Fe3 transport system permease component
AV743_07495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV743_07500	COG1840	ABC-type Fe3 transport system, periplasmic component
AV743_07530	COG2233	PERMEase
AV743_07535	COG0840	transmembrane signaling receptor activity
AV743_07540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV743_07570	COG4789	Type iii secretion
AV743_07635	COG4669	(LipO)protein
AV743_07665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV743_07670	COG4790	Type iii secretion
AV743_07675	COG4794	Type iii secretion
AV743_07680	COG4791	protein targeting
AV743_07685	COG4792	protein secretion
AV743_07700	COG1595	DNA-templated transcription, initiation
AV743_07720	COG2770	Histidine kinase
AV743_07720	COG2208	phosphoserine phosphatase activity
AV743_07730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AV743_07735	COG2172	sigma factor antagonist activity
AV743_07740	COG1366	Belongs to the anti-sigma-factor antagonist family
AV743_07745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_07780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AV743_07810	COG1017	nitric oxide dioxygenase activity
AV743_07810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV743_07815	COG1959	2 iron, 2 sulfur cluster binding
AV743_07820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_07840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AV743_07845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AV743_07850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV743_07855	COG0084	hydrolase, TatD family'
AV743_07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_07880	COG1126	abc transporter atp-binding protein
AV743_07890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV743_07905	COG0028	Belongs to the TPP enzyme family
AV743_07925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_07975	COG4336	lyase activity
AV743_07985	COG2205	protein histidine kinase activity
AV743_07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_07990	COG2197	response regulator
AV743_08020	COG3121	Chaperone
AV743_08025	COG3188	usher protein
AV743_08030	COG3539	Fimbrial protein
AV743_08035	COG2831	hemolysin activation secretion protein
AV743_08050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_08110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_08115	COG0765	amino acid transport
AV743_08120	COG1126	abc transporter atp-binding protein
AV743_08125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV743_08130	COG1758	RNA polymerase activity
AV743_08135	COG0194	GDP metabolic process
AV743_08140	COG3258	Cytochrome c
AV743_08145	COG2863	cytochrome
AV743_08150	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_08155	COG0791	NLP P60 protein
AV743_08160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV743_08180	COG1561	YicC-like family, N-terminal region
AV743_08185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AV743_08200	COG0840	transmembrane signaling receptor activity
AV743_08205	COG2199	diguanylate cyclase activity
AV743_08205	COG2200	EAL domain
AV743_08210	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AV743_08225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV743_08235	COG3852	Histidine kinase
AV743_08240	COG2204	response regulator
AV743_08245	COG0583	DNA-binding transcription factor activity
AV743_08250	COG1741	Belongs to the pirin family
AV743_08255	COG1741	Belongs to the pirin family
AV743_08260	COG3842	ATPase activity
AV743_08265	COG1178	ABC-type Fe3 transport system permease component
AV743_08270	COG1840	ABC-type Fe3 transport system, periplasmic component
AV743_08280	COG0583	DNA-binding transcription factor activity
AV743_08290	COG0656	L-ascorbic acid biosynthetic process
AV743_08305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AV743_08310	COG0583	DNA-binding transcription factor activity
AV743_08325	COG0783	Belongs to the Dps family
AV743_08345	COG0463	Glycosyl transferase, family 2
AV743_08365	COG0438	transferase activity, transferring glycosyl groups
AV743_08380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AV743_08400	COG0300	oxidoreductase activity
AV743_08445	COG0861	Integral membrane protein TerC family
AV743_08450	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_08470	COG0714	Associated with various cellular activities
AV743_08505	COG3119	arylsulfatase activity
AV743_08525	COG0431	NADPH-dependent FMN reductase
AV743_08555	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_08560	COG0583	DNA-binding transcription factor activity
AV743_08580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AV743_08580	COG2111	Na H antiporter
AV743_08585	COG1006	Multisubunit Na H antiporter MnhC subunit
AV743_08590	COG0651	ATP synthesis coupled electron transport
AV743_08595	COG1863	multisubunit Na H antiporter MnhE subunit
AV743_08600	COG2212	antiporter activity
AV743_08630	COG0590	tRNA wobble adenosine to inosine editing
AV743_08635	COG1619	proteins homologs of microcin C7 resistance protein MccF
AV743_08640	COG1024	Enoyl-CoA hydratase
AV743_08655	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_08660	COG0488	(ABC) transporter
AV743_08695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV743_08705	COG2252	PERMEase
AV743_08710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AV743_08720	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AV743_08725	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AV743_08730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AV743_08755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AV743_08760	COG0789	Transcriptional regulator
AV743_08770	COG0678	peroxiredoxin activity
AV743_08770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV743_08780	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AV743_08785	COG0584	glycerophosphoryl diester phosphodiesterase
AV743_08790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV743_08800	COG4181	ATPase activity
AV743_08810	COG2823	Periplasmic or secreted lipoprotein
AV743_08820	COG3237	CsbD-like
AV743_08850	COG2833	Protein of unknown function (DUF455)
AV743_08855	COG2951	lytic endotransglycosylase activity
AV743_08875	COG1522	sequence-specific DNA binding
AV743_08885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AV743_08890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AV743_08895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AV743_08900	COG0196	riboflavin kinase activity
AV743_08905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AV743_08925	COG0210	DNA helicase
AV743_08930	COG4771	TonB-dependent receptor
AV743_08935	COG0488	(ABC) transporter
AV743_08940	COG2890	protein-(glutamine-N5) methyltransferase activity
AV743_08945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AV743_08950	COG2171	N-acyltransferase activity
AV743_08985	COG1278	Cold shock
AV743_09005	COG0544	peptidyl-prolyl cis-trans isomerase activity
AV743_09010	COG0740	serine-type endopeptidase activity
AV743_09015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AV743_09020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV743_09025	COG0583	DNA-binding transcription factor activity
AV743_09030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_09055	COG0183	Belongs to the thiolase family
AV743_09060	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_09080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AV743_09110	COG3468	outer membrane autotransporter barrel domain protein
AV743_09115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AV743_09125	COG0556	nucleotide-excision repair
AV743_09130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AV743_09140	COG1104	cysteine desulfurase activity
AV743_09145	COG0822	iron-sulfur transferase activity
AV743_09150	COG0316	Belongs to the HesB IscA family
AV743_09155	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AV743_09160	COG0443	Heat shock 70 kDa protein
AV743_09165	COG0633	Ferredoxin
AV743_09185	COG1024	Enoyl-CoA hydratase
AV743_09200	COG3395	kinase activity
AV743_09220	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AV743_09230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_09255	COG0747	negative chemotaxis
AV743_09260	COG0601	transmembrane transport
AV743_09265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_09270	COG4172	Belongs to the ABC transporter superfamily
AV743_09275	COG0154	amidase activity
AV743_09320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AV743_09325	COG0425	Belongs to the sulfur carrier protein TusA family
AV743_09335	COG0228	four-way junction DNA binding
AV743_09340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AV743_09345	COG0336	Belongs to the RNA methyltransferase TrmD family
AV743_09350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AV743_09370	COG0642	Histidine kinase
AV743_09385	COG0525	valine-tRNA ligase activity
AV743_09390	COG0105	UTP biosynthetic process
AV743_09395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AV743_09405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AV743_09410	COG0124	histidyl-tRNA synthetase
AV743_09415	COG2976	Protein conserved in bacteria
AV743_09420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_09425	COG1160	GTP binding
AV743_09430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV743_09435	COG1923	regulation of RNA biosynthetic process
AV743_09440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AV743_09445	COG0330	HflC and HflK could
AV743_09450	COG0330	HflC and HflK could
AV743_09455	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AV743_09460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AV743_09470	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AV743_09480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV743_09510	COG0628	permease
AV743_09515	COG0842	Transport permease protein
AV743_09520	COG1131	(ABC) transporter
AV743_09590	COG0156	8-amino-7-oxononanoate synthase activity
AV743_09600	COG4106	trans-aconitate 2-methyltransferase activity
AV743_09600	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AV743_09605	COG1380	Effector of murein hydrolase LrgA
AV743_09625	COG3284	Transcriptional regulator
AV743_09630	COG1012	belongs to the aldehyde dehydrogenase family
AV743_09645	COG2733	membrane
AV743_09650	COG0583	DNA-binding transcription factor activity
AV743_09655	COG0384	phenazine biosynthesis protein PhzF
AV743_09660	COG5507	3-demethylubiquinone-9 3-methyltransferase
AV743_09665	COG2169	Transcriptional regulator
AV743_09695	COG0659	secondary active sulfate transmembrane transporter activity
AV743_09750	COG2207	Transcriptional regulator
AV743_09880	COG2346	COG2346, Truncated hemoglobins
AV743_09925	COG0183	Belongs to the thiolase family
AV743_09940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_09945	COG0633	Ferredoxin
AV743_09955	COG1024	Enoyl-CoA hydratase
AV743_09960	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AV743_09965	COG4638	Rieske (2fe-2S)
AV743_09975	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_09995	COG2224	Isocitrate lyase
AV743_10000	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV743_10000	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV743_10015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AV743_10020	COG0322	excinuclease ABC activity
AV743_10025	COG1472	Belongs to the glycosyl hydrolase 3 family
AV743_10030	COG0736	holo-[acyl-carrier-protein] synthase activity
AV743_10035	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AV743_10045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV743_10050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV743_10075	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AV743_10090	COG2032	superoxide dismutase activity
AV743_10105	COG1024	Enoyl-CoA hydratase
AV743_10115	COG1802	Transcriptional regulator
AV743_10125	COG0183	Belongs to the thiolase family
AV743_10130	COG1942	4-Oxalocrotonate Tautomerase
AV743_10140	COG4176	ABC-type proline glycine betaine transport system permease component
AV743_10160	COG2814	Major facilitator Superfamily
AV743_10165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AV743_10170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AV743_10190	COG1846	Transcriptional regulator
AV743_10195	COG2814	Major facilitator Superfamily
AV743_10200	COG0495	leucyl-tRNA aminoacylation
AV743_10215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AV743_10225	COG0154	amidase activity
AV743_10230	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_10280	COG1530	ribonuclease E activity
AV743_10285	COG0077	Prephenate dehydratase
AV743_10300	COG1132	(ABC) transporter
AV743_10305	COG0859	PFAM glycosyl transferase family 9
AV743_10330	COG2194	sulfuric ester hydrolase activity
AV743_10335	COG0438	transferase activity, transferring glycosyl groups
AV743_10340	COG0463	Glycosyl transferase, family 2
AV743_10345	COG0726	polysaccharide deacetylase
AV743_10350	COG0438	transferase activity, transferring glycosyl groups
AV743_10365	COG1643	Atp-dependent helicase
AV743_10370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AV743_10370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV743_10375	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AV743_10385	COG0704	Plays a role in the regulation of phosphate uptake
AV743_10390	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AV743_10395	COG1960	acyl-CoA dehydrogenase activity
AV743_10410	COG2094	Belongs to the DNA glycosylase MPG family
AV743_10420	COG1177	transmembrane transport
AV743_10425	COG1176	ABC-type spermidine putrescine transport system, permease component I
AV743_10430	COG3842	ATPase activity
AV743_10435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AV743_10440	COG3642	lipopolysaccharide core region biosynthetic process
AV743_10450	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AV743_10455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_10485	COG0372	Belongs to the citrate synthase family
AV743_10490	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AV743_10495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AV743_10500	COG1053	succinate dehydrogenase
AV743_10505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AV743_10510	COG2009	succinate dehydrogenase
AV743_10515	COG2188	Transcriptional regulator
AV743_10520	COG0039	L-malate dehydrogenase activity
AV743_10575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_10585	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AV743_10615	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AV743_10620	COG0148	phosphopyruvate hydratase activity
AV743_10635	COG0504	CTP synthase activity
AV743_10660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_10670	COG0747	negative chemotaxis
AV743_10675	COG4172	Belongs to the ABC transporter superfamily
AV743_10680	COG1446	asparaginase
AV743_10710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV743_10725	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AV743_10730	COG0697	spore germination
AV743_10735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_10745	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AV743_10750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_10755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_10760	COG0791	NLP P60 protein
AV743_10775	COG0583	DNA-binding transcription factor activity
AV743_10790	COG0583	DNA-binding transcription factor activity
AV743_10800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV743_10815	COG0670	Belongs to the BI1 family
AV743_10820	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_10830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV743_10840	COG1381	Involved in DNA repair and RecF pathway recombination
AV743_10845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AV743_10850	COG0571	ribonuclease III activity
AV743_10855	COG0681	Belongs to the peptidase S26 family
AV743_10860	COG0481	GTPase activity
AV743_10865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV743_10890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV743_10895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV743_10910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV743_10915	COG0416	fatty acid biosynthetic process
AV743_10920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AV743_10925	COG1399	metal-binding, possibly nucleic acid-binding protein
AV743_10930	COG0424	maF-like protein
AV743_10940	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV743_10955	COG3022	response to hydroperoxide
AV743_10970	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_11015	COG2814	Major facilitator Superfamily
AV743_11035	COG3706	GGDEF domain
AV743_11060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AV743_11065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AV743_11070	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AV743_11075	COG1674	ftsk spoiiie
AV743_11080	COG0492	ferredoxin-NADP+ reductase activity
AV743_11085	COG1193	negative regulation of DNA recombination
AV743_11100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV743_11115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AV743_11120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AV743_11125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AV743_11135	COG0745	RESPONSE REGULATOR receiver
AV743_11180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV743_11200	COG0612	Peptidase, M16
AV743_11210	COG0443	Heat shock 70 kDa protein
AV743_11220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AV743_11230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AV743_11235	COG1420	regulation of RNA biosynthetic process
AV743_11240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AV743_11245	COG0497	DNA recombination
AV743_11250	COG0735	belongs to the Fur family
AV743_11255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_11260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AV743_11265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AV743_11300	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV743_11300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AV743_11305	COG4311	Sarcosine oxidase, delta subunit
AV743_11310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_11320	COG0583	DNA-binding transcription factor activity
AV743_11330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AV743_11355	COG4964	Belongs to the GSP D family
AV743_11395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AV743_11415	COG0181	hydroxymethylbilane synthase activity
AV743_11420	COG0861	Integral membrane protein TerC family
AV743_11425	COG0861	Integral membrane protein TerC family
AV743_11430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AV743_11435	COG0045	succinate-CoA ligase (ADP-forming) activity
AV743_11445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AV743_11450	COG0583	DNA-binding transcription factor activity
AV743_11455	COG2137	regulation of response to DNA damage stimulus
AV743_11460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AV743_11470	COG0642	Histidine kinase
AV743_11480	COG1024	Enoyl-CoA hydratase
AV743_11480	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_11485	COG3842	ATPase activity
AV743_11500	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_11520	COG0583	DNA-binding transcription factor activity
AV743_11525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_11535	COG2974	May be involved in recombination
AV743_11540	COG0540	Belongs to the ATCase OTCase family
AV743_11605	COG0776	regulation of translation
AV743_11610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV743_11610	COG0072	phenylalanine-tRNA ligase activity
AV743_11615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AV743_11620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AV743_11625	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AV743_11640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_11650	COG0756	dUTP diphosphatase activity
AV743_11665	COG0500	methyltransferase
AV743_11680	COG0586	Pfam SNARE associated Golgi protein
AV743_11710	COG1609	Transcriptional regulator
AV743_11715	COG4172	Belongs to the ABC transporter superfamily
AV743_11725	COG0601	transmembrane transport
AV743_11730	COG0747	negative chemotaxis
AV743_11750	COG1280	lysine exporter protein (LysE YggA)
AV743_11765	COG2814	Major facilitator Superfamily
AV743_11795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AV743_11810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AV743_11835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_11840	COG1116	anion transmembrane transporter activity
AV743_11850	COG1228	amidohydrolase
AV743_11865	COG0477	Major facilitator Superfamily
AV743_11875	COG3550	peptidyl-serine autophosphorylation
AV743_11890	COG0519	Catalyzes the synthesis of GMP from XMP
AV743_11890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AV743_11915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AV743_11920	COG1012	belongs to the aldehyde dehydrogenase family
AV743_11925	COG0483	inositol monophosphate 1-phosphatase activity
AV743_11930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AV743_11940	COG1045	serine acetyltransferase
AV743_11945	COG0166	Belongs to the GPI family
AV743_11960	COG2197	response regulator
AV743_11975	COG0183	Belongs to the thiolase family
AV743_11990	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_11990	COG1024	Enoyl-CoA hydratase
AV743_11995	COG0183	Belongs to the thiolase family
AV743_12030	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_12045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV743_12045	COG1017	nitric oxide dioxygenase activity
AV743_12060	COG1335	isochorismatase
AV743_12065	COG2309	aminopeptidase activity
AV743_12075	COG3473	Maleate cis-trans isomerase
AV743_12085	COG2080	2 iron, 2 sulfur cluster binding
AV743_12120	COG1846	Transcriptional regulator
AV743_12140	COG1649	PFAM Uncharacterised BCR, COG1649
AV743_12140	COG0726	polysaccharide deacetylase
AV743_12145	COG1215	transferase activity, transferring glycosyl groups
AV743_12155	COG1902	pentaerythritol trinitrate reductase activity
AV743_12180	COG0251	oxidation-reduction process
AV743_12190	COG1832	CoA-binding protein
AV743_12195	COG1414	Transcriptional regulator
AV743_12200	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV743_12200	COG1902	pentaerythritol trinitrate reductase activity
AV743_12210	COG3842	ATPase activity
AV743_12220	COG1176	ABC-type spermidine putrescine transport system, permease component I
AV743_12235	COG0583	DNA-binding transcription factor activity
AV743_12245	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_12250	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AV743_12255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_12270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AV743_12275	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_12300	COG0527	aspartate kinase activity
AV743_12305	COG0037	tRNA processing
AV743_12315	COG0825	malonyl-CoA metabolic process
AV743_12325	COG0215	cysteine-tRNA ligase activity
AV743_12340	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_12345	COG1968	undecaprenyl-diphosphatase activity
AV743_12350	COG1253	flavin adenine dinucleotide binding
AV743_12375	COG0668	transmembrane transport
AV743_12420	COG3360	Dodecin
AV743_12425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AV743_12430	COG2850	peptidyl-arginine hydroxylation
AV743_12435	COG3539	Fimbrial protein
AV743_12440	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AV743_12445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_12460	COG0009	L-threonylcarbamoyladenylate synthase
AV743_12465	COG2321	neutral zinc metallopeptidase
AV743_12485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AV743_12490	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AV743_12495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV743_12505	COG1074	ATP-dependent DNA helicase activity
AV743_12525	COG1686	Belongs to the peptidase S11 family
AV743_12535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AV743_12540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AV743_12545	COG4974	Belongs to the 'phage' integrase family
AV743_12550	COG0583	DNA-binding transcription factor activity
AV743_12555	COG0028	Belongs to the TPP enzyme family
AV743_12570	COG0028	Belongs to the TPP enzyme family
AV743_12575	COG1126	abc transporter atp-binding protein
AV743_12580	COG0765	amino acid transport
AV743_12595	COG1414	Transcriptional regulator
AV743_12600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_12605	COG0009	L-threonylcarbamoyladenylate synthase
AV743_12610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AV743_12615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AV743_12620	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AV743_12630	COG2944	sequence-specific DNA binding
AV743_12640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AV743_12695	COG1126	abc transporter atp-binding protein
AV743_12700	COG0765	amino acid transport
AV743_12705	COG0765	amino acid transport
AV743_12710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_12720	COG2423	ornithine cyclodeaminase activity
AV743_12735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AV743_12740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV743_12750	COG0189	ligase activity
AV743_12755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AV743_12760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AV743_12765	COG2197	response regulator
AV743_12785	COG3706	GGDEF domain
AV743_12800	COG0135	phosphoribosylanthranilate isomerase activity
AV743_12815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_12820	COG0101	tRNA pseudouridine synthase activity
AV743_12830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AV743_12835	COG0473	3-isopropylmalate dehydrogenase activity
AV743_12840	COG0066	3-isopropylmalate dehydratase activity
AV743_12845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AV743_12855	COG1122	ATPase activity
AV743_12890	COG0243	molybdopterin cofactor binding
AV743_12890	COG3383	formate dehydrogenase (NAD+) activity
AV743_12920	COG0489	protein tyrosine kinase activity
AV743_12925	COG0746	molybdenum cofactor guanylyltransferase activity
AV743_12930	COG0303	'Molybdopterin
AV743_12935	COG1763	Mo-molybdopterin cofactor biosynthetic process
AV743_12940	COG4783	chaperone-mediated protein folding
AV743_12945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AV743_12950	COG5001	Diguanylate cyclase
AV743_12970	COG3842	ATPase activity
AV743_12980	COG0406	alpha-ribazole phosphatase activity
AV743_12990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AV743_13000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AV743_13030	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AV743_13035	COG1960	acyl-CoA dehydrogenase activity
AV743_13045	COG2867	negative regulation of translational initiation
AV743_13050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AV743_13055	COG3706	GGDEF domain
AV743_13060	COG0330	HflC and HflK could
AV743_13075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AV743_13075	COG0519	Catalyzes the synthesis of GMP from XMP
AV743_13085	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AV743_13090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV743_13095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AV743_13100	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_13110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV743_13115	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_13120	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AV743_13125	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_13130	COG0750	zinc metalloprotease
AV743_13135	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AV743_13145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV743_13150	COG0233	cytoplasmic translational termination
AV743_13155	COG0528	UMP kinase activity
AV743_13160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AV743_13165	COG0052	Belongs to the universal ribosomal protein uS2 family
AV743_13170	COG0024	Methionine aminopeptidase
AV743_13175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AV743_13205	COG0285	dihydrofolate synthase activity
AV743_13240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV743_13250	COG1677	Flagellar hook-basal body complex protein FliE
AV743_13260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV743_13270	COG1157	protein secretion by the type III secretion system
AV743_13295	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_13315	COG1338	Plays a role in the flagellum-specific transport system
AV743_13335	COG0840	transmembrane signaling receptor activity
AV743_13340	COG0840	transmembrane signaling receptor activity
AV743_13345	COG0840	transmembrane signaling receptor activity
AV743_13355	COG1256	bacterial-type flagellum assembly
AV743_13365	COG1706	bacterial-type flagellum-dependent cell motility
AV743_13370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_13375	COG4786	Flagellar basal body rod
AV743_13385	COG1749	Flagellar hook protein flgE
AV743_13390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AV743_13395	COG1558	bacterial-type flagellum-dependent cell motility
AV743_13400	COG1815	bacterial-type flagellum-dependent cell motility
AV743_13440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_13450	COG1126	abc transporter atp-binding protein
AV743_13465	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_13485	COG1338	Plays a role in the flagellum-specific transport system
AV743_13505	COG0840	transmembrane signaling receptor activity
AV743_13510	COG0840	transmembrane signaling receptor activity
AV743_13515	COG0840	transmembrane signaling receptor activity
AV743_13525	COG1256	bacterial-type flagellum assembly
AV743_13535	COG1706	bacterial-type flagellum-dependent cell motility
AV743_13540	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_13545	COG4786	Flagellar basal body rod
AV743_13555	COG1749	Flagellar hook protein flgE
AV743_13560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AV743_13565	COG1558	bacterial-type flagellum-dependent cell motility
AV743_13570	COG1815	bacterial-type flagellum-dependent cell motility
AV743_13610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_13620	COG1126	abc transporter atp-binding protein
AV743_13635	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_13655	COG1338	Plays a role in the flagellum-specific transport system
AV743_13675	COG0840	transmembrane signaling receptor activity
AV743_13680	COG0840	transmembrane signaling receptor activity
AV743_13685	COG0840	transmembrane signaling receptor activity
AV743_13695	COG1256	bacterial-type flagellum assembly
AV743_13705	COG1706	bacterial-type flagellum-dependent cell motility
AV743_13710	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_13715	COG4786	Flagellar basal body rod
AV743_13725	COG1749	Flagellar hook protein flgE
AV743_13730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AV743_13735	COG1558	bacterial-type flagellum-dependent cell motility
AV743_13740	COG1815	bacterial-type flagellum-dependent cell motility
AV743_13780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_13790	COG1126	abc transporter atp-binding protein
AV743_13805	COG4948	Mandelate Racemase Muconate Lactonizing
AV743_13810	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_13820	COG0066	3-isopropylmalate dehydratase activity
AV743_13835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_13845	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_13855	COG1802	Transcriptional regulator
AV743_13870	COG0583	DNA-binding transcription factor activity
AV743_13890	COG1695	Transcriptional regulator
AV743_13900	COG3568	Endonuclease Exonuclease Phosphatase
AV743_13905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_13925	COG3842	ATPase activity
AV743_13935	COG0406	alpha-ribazole phosphatase activity
AV743_13950	COG0505	Belongs to the CarA family
AV743_13955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AV743_13990	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AV743_13995	COG1960	acyl-CoA dehydrogenase activity
AV743_14005	COG2867	negative regulation of translational initiation
AV743_14010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AV743_14015	COG3706	GGDEF domain
AV743_14020	COG0330	HflC and HflK could
AV743_14035	COG0519	Catalyzes the synthesis of GMP from XMP
AV743_14035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AV743_14045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AV743_14050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV743_14055	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AV743_14060	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_14070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV743_14075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_14080	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AV743_14085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_14090	COG0750	zinc metalloprotease
AV743_14095	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AV743_14105	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV743_14110	COG0233	cytoplasmic translational termination
AV743_14115	COG0528	UMP kinase activity
AV743_14120	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AV743_14125	COG0052	Belongs to the universal ribosomal protein uS2 family
AV743_14130	COG0024	Methionine aminopeptidase
AV743_14135	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AV743_14165	COG0285	dihydrofolate synthase activity
AV743_14200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV743_14210	COG1677	Flagellar hook-basal body complex protein FliE
AV743_14220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV743_14230	COG1157	protein secretion by the type III secretion system
AV743_14255	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_14275	COG1338	Plays a role in the flagellum-specific transport system
AV743_14295	COG0840	transmembrane signaling receptor activity
AV743_14300	COG0840	transmembrane signaling receptor activity
AV743_14305	COG0840	transmembrane signaling receptor activity
AV743_14315	COG1256	bacterial-type flagellum assembly
AV743_14325	COG1706	bacterial-type flagellum-dependent cell motility
AV743_14330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_14335	COG4786	Flagellar basal body rod
AV743_14345	COG1749	Flagellar hook protein flgE
AV743_14350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AV743_14355	COG1558	bacterial-type flagellum-dependent cell motility
AV743_14360	COG1815	bacterial-type flagellum-dependent cell motility
AV743_14400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_14410	COG1126	abc transporter atp-binding protein
AV743_14425	COG4948	Mandelate Racemase Muconate Lactonizing
AV743_14430	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_14440	COG0066	3-isopropylmalate dehydratase activity
AV743_14455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_14465	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_14475	COG1802	Transcriptional regulator
AV743_14490	COG0583	DNA-binding transcription factor activity
AV743_14510	COG1695	Transcriptional regulator
AV743_14520	COG3568	Endonuclease Exonuclease Phosphatase
AV743_14525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_14550	COG0420	3'-5' exonuclease activity
AV743_14555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_14585	COG0395	ABC-type sugar transport system, permease component
AV743_14595	COG3842	ATPase activity
AV743_14620	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_14625	COG1053	succinate dehydrogenase
AV743_14655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_14680	COG0602	queuosine metabolic process
AV743_14685	COG0720	synthase
AV743_14690	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_14695	COG0235	Class ii aldolase
AV743_14720	COG3210	domain, Protein
AV743_14720	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AV743_14720	COG3064	Membrane
AV743_14725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AV743_14725	COG0047	phosphoribosylformylglycinamidine synthase activity
AV743_14730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AV743_14735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AV743_14740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_14755	COG3539	Fimbrial protein
AV743_14765	COG2050	protein possibly involved in aromatic compounds catabolism
AV743_14770	COG1024	Enoyl-CoA hydratase
AV743_14775	COG1012	belongs to the aldehyde dehydrogenase family
AV743_14795	COG2151	metal-sulfur cluster biosynthetic enzyme
AV743_14800	COG3396	Phenylacetate-CoA oxygenase
AV743_14805	COG3460	Phenylacetate-CoA oxygenase
AV743_14810	COG3396	Phenylacetate-CoA oxygenase
AV743_14815	COG3327	negative regulation of DNA-templated transcription, initiation
AV743_14825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AV743_14830	COG0501	Belongs to the peptidase M48B family
AV743_14835	COG1162	GTPase activity
AV743_14850	COG0601	transmembrane transport
AV743_14855	COG0747	negative chemotaxis
AV743_14900	COG0668	transmembrane transport
AV743_14905	COG0165	Argininosuccinate lyase
AV743_14925	COG0542	response to heat
AV743_14930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV743_14945	COG0494	nUDIX hydrolase
AV743_14950	COG3530	Putative quorum-sensing-regulated virulence factor
AV743_14960	COG1595	DNA-templated transcription, initiation
AV743_14965	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_15000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_15005	COG0765	amino acid transport
AV743_15010	COG0765	amino acid transport
AV743_15035	COG2988	succinylglutamate desuccinylase activity
AV743_15060	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_15065	COG2084	Dehydrogenase
AV743_15080	COG1619	proteins homologs of microcin C7 resistance protein MccF
AV743_15095	COG2814	Major facilitator Superfamily
AV743_15105	COG0583	DNA-binding transcription factor activity
AV743_15160	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AV743_15165	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_15170	COG3243	poly(R)-hydroxyalkanoic acid synthase
AV743_15180	COG0564	pseudouridine synthase activity
AV743_15190	COG1199	ATP-dependent helicase activity
AV743_15195	COG2183	response to ionizing radiation
AV743_15200	COG0180	Tryptophanyl-tRNA synthetase
AV743_15225	COG4774	siderophore transport
AV743_15230	COG3712	iron ion homeostasis
AV743_15235	COG1595	DNA-templated transcription, initiation
AV743_15260	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_15270	COG0583	DNA-binding transcription factor activity
AV743_15275	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_15280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AV743_15285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV743_15290	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV743_15295	COG0567	Dehydrogenase, E1 component
AV743_15305	COG1522	sequence-specific DNA binding
AV743_15315	COG0280	phosphate acetyltransferase
AV743_15315	COG0281	malic enzyme
AV743_15320	COG3539	Fimbrial protein
AV743_15340	COG0613	PHP domain protein
AV743_15350	COG0658	competence protein
AV743_15350	COG2333	competence protein COMEC
AV743_15370	COG0084	hydrolase, TatD family'
AV743_15375	COG1136	(ABC) transporter
AV743_15390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AV743_15400	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_15405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AV743_15420	COG1022	Amp-dependent synthetase and ligase
AV743_15455	COG2205	protein histidine kinase activity
AV743_15460	COG0745	RESPONSE REGULATOR receiver
AV743_15475	COG1295	ribonuclease BN
AV743_15490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV743_15520	COG1534	Rna-binding protein
AV743_15525	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AV743_15530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV743_15540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV743_15550	COG0248	Ppx GppA phosphatase
AV743_15575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV743_15595	COG2732	(Barnase) inhibitor
AV743_15615	COG0436	Aminotransferase
AV743_15620	COG0741	lytic transglycosylase activity
AV743_15625	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AV743_15650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV743_15650	COG1648	precorrin-2 dehydrogenase activity
AV743_15655	COG3468	outer membrane autotransporter barrel domain protein
AV743_15665	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AV743_15670	COG2027	D-alanyl-D-alanine carboxypeptidase
AV743_15675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AV743_15680	COG0343	queuine tRNA-ribosyltransferase activity
AV743_15685	COG1862	Preprotein translocase
AV743_15690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV743_15695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV743_15710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AV743_15715	COG1702	phosphate starvation-inducible protein PhoH
AV743_15720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AV743_15725	COG4535	Mg2 and Co2 transporter CorC
AV743_15735	COG0667	Aldo Keto reductase
AV743_15760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AV743_15765	COG0745	RESPONSE REGULATOR receiver
AV743_15770	COG2201	protein-glutamate methylesterase activity
AV743_15780	COG0840	transmembrane signaling receptor activity
AV743_15785	COG0835	chemotaxis
AV743_15790	COG0643	Histidine kinase
AV743_15790	COG2198	Histidine kinase
AV743_15820	COG1191	sigma factor activity
AV743_15835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV743_15845	COG0739	heme binding
AV743_15855	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV743_15865	COG0306	phosphate transporter
AV743_15870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AV743_15905	COG0625	glutathione transferase activity
AV743_15920	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV743_15925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AV743_15930	COG0126	phosphoglycerate kinase activity
AV743_15935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AV743_15940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV743_15945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AV743_15955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV743_15960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV743_15965	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV743_15970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AV743_15980	COG4566	intracellular signal transduction
AV743_15990	COG0339	signal peptide processing
AV743_15995	COG1999	signal sequence binding
AV743_16025	COG1187	pseudouridine synthase activity
AV743_16030	COG3161	chorismate lyase activity
AV743_16045	COG0667	Aldo Keto reductase
AV743_16055	COG0335	large ribosomal subunit rRNA binding
AV743_16085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AV743_16090	COG4208	sulfate ABC transporter
AV743_16095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AV743_16110	COG0450	alkyl hydroperoxide reductase
AV743_16115	COG1960	acyl-CoA dehydrogenase activity
AV743_16130	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV743_16135	COG2951	lytic endotransglycosylase activity
AV743_16150	COG1596	polysaccharide export
AV743_16150	COG1555	photosystem II stabilization
AV743_16155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AV743_16160	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AV743_16165	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AV743_16185	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AV743_16190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AV743_16195	COG0287	Prephenate dehydrogenase
AV743_16205	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AV743_16220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV743_16230	COG2814	Major facilitator Superfamily
AV743_16255	COG0583	DNA-binding transcription factor activity
AV743_16295	COG0583	DNA-binding transcription factor activity
AV743_16310	COG0179	Fumarylacetoacetate (FAA) hydrolase
AV743_16335	COG1053	succinate dehydrogenase
AV743_16340	COG1012	belongs to the aldehyde dehydrogenase family
AV743_16345	COG2079	MmgE PrpD family protein
AV743_16355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_16365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AV743_16410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV743_16425	COG0667	Aldo Keto reductase
AV743_16435	COG5265	(ABC) transporter
AV743_16485	COG0439	Biotin carboxylase
AV743_16490	COG2188	Transcriptional regulator
AV743_16515	COG0511	ligase activity, forming carbon-carbon bonds
AV743_16545	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AV743_16565	COG0500	methyltransferase
AV743_16570	COG5265	(ABC) transporter
AV743_16590	COG0308	aminopeptidase N
AV743_16595	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AV743_16610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AV743_16615	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AV743_16620	COG0560	Phosphoserine phosphatase
AV743_16625	COG0583	DNA-binding transcription factor activity
AV743_16630	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_16635	COG0028	Belongs to the TPP enzyme family
AV743_16650	COG4774	siderophore transport
AV743_16655	COG4774	siderophore transport
AV743_16665	COG1007	ATP synthesis coupled electron transport
AV743_16680	COG0713	ATP synthesis coupled electron transport
AV743_16690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_16695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AV743_16700	COG1034	ATP synthesis coupled electron transport
AV743_16710	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AV743_16715	COG0649	NAD binding
AV743_16720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_16725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_16730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_16735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_16765	COG0671	phosphoesterase, PA-phosphatase related
AV743_16775	COG1597	lipid kinase activity
AV743_16780	COG0583	DNA-binding transcription factor activity
AV743_16785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV743_16795	COG1733	regulation of RNA biosynthetic process
AV743_16800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV743_16820	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AV743_16840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_16860	COG3608	succinylglutamate desuccinylase aspartoacylase
AV743_16865	COG0626	cystathionine gamma-synthase activity
AV743_16870	COG0583	DNA-binding transcription factor activity
AV743_16905	COG3799	methylaspartate ammonia-lyase activity
AV743_16915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV743_16925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV743_16930	COG0149	triose-phosphate isomerase activity
AV743_16950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AV743_16970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AV743_16985	COG1183	phosphatidylcholine synthase activity
AV743_16990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AV743_16995	COG0440	acetolactate synthase activity
AV743_17000	COG0028	Belongs to the TPP enzyme family
AV743_17100	COG1464	Belongs to the NlpA lipoprotein family
AV743_17115	COG0410	ABC transporter
AV743_17130	COG4211	Belongs to the binding-protein-dependent transport system permease family
AV743_17135	COG0683	leucine binding
AV743_17140	COG0154	amidase activity
AV743_17145	COG0288	reversible hydration of carbon dioxide
AV743_17160	COG0514	ATP-dependent DNA helicase (RecQ)
AV743_17165	COG2255	four-way junction helicase activity
AV743_17180	COG0632	four-way junction helicase activity
AV743_17185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AV743_17205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV743_17215	COG0006	proline dipeptidase activity
AV743_17240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_17255	COG4783	chaperone-mediated protein folding
AV743_17260	COG0429	hydrolase of the alpha beta-hydrolase fold
AV743_17290	COG0513	Belongs to the DEAD box helicase family
AV743_17310	COG1546	Belongs to the CinA family
AV743_17310	COG1058	Belongs to the CinA family
AV743_17315	COG1414	Transcriptional regulator
AV743_17335	COG0167	dihydroorotate dehydrogenase activity
AV743_17340	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AV743_17355	COG0583	DNA-binding transcription factor activity
AV743_17415	COG0281	malic enzyme
AV743_17415	COG0280	phosphate acetyltransferase
AV743_17430	COG0601	transmembrane transport
AV743_17435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_17440	COG4172	Belongs to the ABC transporter superfamily
AV743_17470	COG0640	Transcriptional regulator
AV743_17485	COG3135	benzoate transporter
AV743_17490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AV743_17495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AV743_17500	COG0742	ribosomal rna small subunit methyltransferase
AV743_17515	COG3639	organic phosphonate transmembrane transporter activity
AV743_17520	COG3639	organic phosphonate transmembrane transporter activity
AV743_17560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AV743_17565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV743_17575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AV743_17580	COG1058	Belongs to the CinA family
AV743_17580	COG1546	Belongs to the CinA family
AV743_17585	COG0284	orotidine-5'-phosphate decarboxylase activity
AV743_17590	COG1252	NADH dehydrogenase
AV743_17605	COG3468	outer membrane autotransporter barrel domain protein
AV743_17610	COG0459	protein refolding
AV743_17615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AV743_17635	COG1053	succinate dehydrogenase
AV743_17645	COG0583	DNA-binding transcription factor activity
AV743_17665	COG3706	GGDEF domain
AV743_17705	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AV743_17715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_17725	COG0069	glutamate synthase activity
AV743_17730	COG2391	methyltransferase activity
AV743_17735	COG0679	Auxin Efflux Carrier
AV743_17740	COG2153	protein acetylation
AV743_17760	COG0557	exoribonuclease II activity
AV743_17765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV743_17775	COG3128	pkhd-type hydroxylase
AV743_17780	COG0776	regulation of translation
AV743_17805	COG0745	RESPONSE REGULATOR receiver
AV743_17810	COG0642	Histidine kinase
AV743_17815	COG3158	transport of potassium into the cell
AV743_17820	COG0137	argininosuccinate synthase activity
AV743_17825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AV743_17830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV743_17840	COG0583	DNA-binding transcription factor activity
AV743_17850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV743_17870	COG2186	Transcriptional regulator
AV743_17890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_17895	COG0450	alkyl hydroperoxide reductase
AV743_17900	COG2205	protein histidine kinase activity
AV743_17910	COG0745	RESPONSE REGULATOR receiver
AV743_17915	COG1214	PFAM Peptidase M22, glycoprotease
AV743_17920	COG1573	uracil-dna glycosylase
AV743_17925	COG0477	Major facilitator Superfamily
AV743_17930	COG1196	nuclear chromosome segregation
AV743_17940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AV743_17960	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV743_17965	COG1122	ATPase activity
AV743_17970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AV743_17975	COG1268	BioY protein
AV743_17990	COG0411	ABC transporter
AV743_17995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AV743_18010	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_18025	COG0411	ABC transporter
AV743_18030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AV743_18035	COG2878	Part of a membrane complex involved in electron transport
AV743_18050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AV743_18055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AV743_18060	COG0251	oxidation-reduction process
AV743_18070	COG3228	Belongs to the MtfA family
AV743_18075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV743_18085	COG0133	tryptophan synthase activity
AV743_18090	COG0159	tryptophan synthase activity
AV743_18115	COG1530	ribonuclease E activity
AV743_18125	COG0546	phosphoglycolate phosphatase activity
AV743_18130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AV743_18135	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AV743_18205	COG1196	nuclear chromosome segregation
AV743_18275	COG2135	peptidase activity
AV743_18290	COG0494	nUDIX hydrolase
AV743_18295	COG0442	prolyl-tRNA aminoacylation
AV743_18300	COG0824	Thioesterase
AV743_18305	COG0811	peptide transport
AV743_18310	COG0848	biopolymer transport protein
AV743_18320	COG0823	Involved in the tonB-independent uptake of proteins
AV743_18335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV743_18340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AV743_18395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_18400	COG3568	Endonuclease Exonuclease Phosphatase
AV743_18405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AV743_18440	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AV743_18450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AV743_18465	COG1137	ATPase activity
AV743_18470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AV743_18480	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AV743_18485	COG2010	Cytochrome c
AV743_18485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV743_18500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV743_18535	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_18545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AV743_18550	COG2890	protein-(glutamine-N5) methyltransferase activity
AV743_18555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AV743_18560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AV743_18600	COG1960	acyl-CoA dehydrogenase activity
AV743_18610	COG0183	Belongs to the thiolase family
AV743_18615	COG1522	sequence-specific DNA binding
AV743_18620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AV743_18640	COG1024	Enoyl-CoA hydratase
AV743_18655	COG0604	alcohol dehydrogenase
AV743_18660	COG2072	flavoprotein involved in K transport
AV743_18675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AV743_18685	COG1960	acyl-CoA dehydrogenase activity
AV743_18690	COG1960	acyl-CoA dehydrogenase activity
AV743_18695	COG0277	FAD linked oxidase domain protein
AV743_18705	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_18730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_18740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_18745	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_18750	COG1960	acyl-CoA dehydrogenase activity
AV743_18770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV743_18775	COG1024	Enoyl-CoA hydratase
AV743_18780	COG1960	acyl-CoA dehydrogenase activity
AV743_18800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AV743_18805	COG0022	dehydrogenase e1 component
AV743_18810	COG1024	Enoyl-CoA hydratase
AV743_18815	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV743_18835	COG0683	leucine binding
AV743_18840	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_18845	COG0411	ABC transporter
AV743_18850	COG0410	ABC transporter
AV743_18855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV743_18870	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_18895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AV743_18900	COG0793	Belongs to the peptidase S41A family
AV743_18905	COG4942	peptidase
AV743_18910	COG0588	phosphoglycerate mutase activity
AV743_18920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV743_18925	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AV743_18930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AV743_18935	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_18950	COG2226	methyltransferase
AV743_18955	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AV743_18970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_18995	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_19020	COG1335	isochorismatase
AV743_19025	COG2309	aminopeptidase activity
AV743_19035	COG3473	Maleate cis-trans isomerase
AV743_19045	COG2068	MobA-Related Protein
AV743_19065	COG0569	domain protein
AV743_19070	COG2204	response regulator
AV743_19075	COG5000	phosphorelay sensor kinase activity
AV743_19085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV743_19085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV743_19095	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AV743_19120	COG0583	DNA-binding transcription factor activity
AV743_19140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_19145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_19160	COG0758	DNA mediated transformation
AV743_19165	COG1522	sequence-specific DNA binding
AV743_19175	COG0242	peptide deformylase activity
AV743_19180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AV743_19190	COG0546	phosphoglycolate phosphatase activity
AV743_19215	COG1942	4-Oxalocrotonate Tautomerase
AV743_19220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_19245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV743_19265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_19270	COG1024	Enoyl-CoA hydratase
AV743_19275	COG1414	Transcriptional regulator
AV743_19280	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_19285	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_19335	COG0330	HflC and HflK could
AV743_19345	COG0251	oxidation-reduction process
AV743_19355	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AV743_19365	COG0583	DNA-binding transcription factor activity
AV743_19370	COG2814	Major facilitator Superfamily
AV743_19375	COG0129	dihydroxy-acid dehydratase activity
AV743_19380	COG2207	Transcriptional regulator
AV743_19385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV743_19395	COG0657	acetylesterase activity
AV743_19400	COG0747	negative chemotaxis
AV743_19405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV743_19410	COG2808	Putative FMN-binding domain
AV743_19425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AV743_19430	COG1970	mechanosensitive ion channel activity
AV743_19435	COG0723	plastoquinol--plastocyanin reductase activity
AV743_19440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AV743_19445	COG2857	Cytochrome c1
AV743_19450	COG0625	glutathione transferase activity
AV743_19455	COG2969	positive regulation of protein catabolic process
AV743_19500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AV743_19505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AV743_19510	COG4988	ABC transporter
AV743_19520	COG1294	oxidase, subunit
AV743_19555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_19560	COG0405	Gamma-glutamyltransferase
AV743_19570	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_19580	COG0114	fumarate hydratase activity
AV743_19585	COG0802	atpase or kinase
AV743_19590	COG0860	N-Acetylmuramoyl-L-alanine amidase
AV743_19595	COG0586	Pfam SNARE associated Golgi protein
AV743_19600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AV743_19605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AV743_19610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AV743_19625	COG0617	tRNA 3'-terminal CCA addition
AV743_19650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_19655	COG2188	Transcriptional regulator
AV743_19665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_19675	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_19700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV743_19705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AV743_19710	COG1012	belongs to the aldehyde dehydrogenase family
AV743_19740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_19745	COG1024	Enoyl-CoA hydratase
AV743_19765	COG1024	Enoyl-CoA hydratase
AV743_19780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_19785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_19795	COG2226	methyltransferase
AV743_19805	COG1194	a g-specific adenine glycosylase
AV743_19815	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AV743_19820	COG2177	Part of the ABC transporter FtsEX involved in
AV743_19825	COG2884	Cell division ATP-binding protein ftsE
AV743_19830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_19835	COG4597	amino acid ABC transporter
AV743_19840	COG0765	amino acid transport
AV743_19845	COG1126	abc transporter atp-binding protein
AV743_19860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AV743_19865	COG0477	Major facilitator Superfamily
AV743_19875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AV743_19880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AV743_19895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AV743_19900	COG0237	dephospho-CoA kinase activity
AV743_19905	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AV743_19925	COG1538	Outer membrane efflux protein
AV743_19970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV743_19985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AV743_20000	COG1652	LysM domain
AV743_20015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_20020	COG1956	GAF domain-containing protein
AV743_20025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_20050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AV743_20075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_20095	COG0438	transferase activity, transferring glycosyl groups
AV743_20145	COG0629	single-stranded DNA binding
AV743_20150	COG2814	Major facilitator Superfamily
AV743_20165	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AV743_20170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AV743_20185	COG1965	Belongs to the frataxin family
AV743_20200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV743_20205	COG1333	cytochrome c biogenesis protein
AV743_20215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AV743_20230	COG4232	protein-disulfide reductase activity
AV743_20235	COG1324	tolerance protein
AV743_20240	COG0537	adenosine 5'-monophosphoramidase activity
AV743_20245	COG0203	ribosomal protein L17
AV743_20250	COG0202	RNA polymerase activity
AV743_20255	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AV743_20260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AV743_20265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AV743_20270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AV743_20275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV743_20280	COG0201	protein transport
AV743_20285	COG0200	Binds to the 23S rRNA
AV743_20290	COG1841	ribosomal large subunit assembly
AV743_20295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AV743_20300	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AV743_20305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AV743_20310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AV743_20315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AV743_20320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AV743_20325	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AV743_20330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AV743_20350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AV743_20355	COG0255	Belongs to the universal ribosomal protein uL29 family
AV743_20360	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AV743_20365	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AV743_20370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AV743_20375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AV743_20380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AV743_20385	COG0089	rRNA binding
AV743_20390	COG0088	Forms part of the polypeptide exit tunnel
AV743_20395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AV743_20400	COG0051	transcription antitermination factor activity, RNA binding
AV743_20405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AV743_20410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV743_20415	COG0049	tRNA binding
AV743_20420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AV743_20430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AV743_20440	COG0628	permease
AV743_20450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AV743_20460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AV743_20465	COG0351	phosphomethylpyrimidine kinase
AV743_20470	COG2022	thiamine diphosphate biosynthetic process
AV743_20475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AV743_20480	COG4206	TonB-dependent receptor
AV743_20505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AV743_20515	COG3781	membrane
AV743_20520	COG1522	sequence-specific DNA binding
AV743_20525	COG0028	Belongs to the TPP enzyme family
AV743_20535	COG1012	belongs to the aldehyde dehydrogenase family
AV743_20540	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_20545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_20550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AV743_20575	COG2922	Belongs to the Smg family
AV743_20580	COG1629	transport
AV743_20600	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_20605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV743_20620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AV743_20635	COG1960	acyl-CoA dehydrogenase activity
AV743_20655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_20670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AV743_20680	COG1414	Transcriptional regulator
AV743_20685	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_20690	COG2031	fatty acid transporter
AV743_20695	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_20705	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AV743_20710	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AV743_20720	COG4257	antibiotic catabolic process
AV743_20730	COG0753	catalase activity
AV743_20735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_20740	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AV743_20750	COG2175	clavaminate synthase activity
AV743_20755	COG1473	amidohydrolase
AV743_20760	COG4608	Belongs to the ABC transporter superfamily
AV743_20765	COG0444	Belongs to the ABC transporter superfamily
AV743_20775	COG0601	transmembrane transport
AV743_20780	COG0747	negative chemotaxis
AV743_20785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AV743_20800	COG5002	protein histidine kinase activity
AV743_20800	COG3850	Histidine kinase
AV743_20820	COG0436	Aminotransferase