locus-tag	class	description
ASC23_00005	COG0445	tRNA wobble uridine modification
ASC23_00015	COG1192	Involved in chromosome partitioning
ASC23_00025	COG1475	DNA binding
ASC23_00030	COG0252	asparaginase activity
ASC23_00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASC23_00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASC23_00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASC23_00080	COG0081	regulation of translation
ASC23_00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASC23_00090	COG0222	ribosome binding
ASC23_00095	COG0085	RNA polymerase activity
ASC23_00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASC23_00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_00165	COG1024	Enoyl-CoA hydratase
ASC23_00185	COG0752	glycyl-tRNA synthetase alpha subunit
ASC23_00190	COG0751	glycine-tRNA ligase activity
ASC23_00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASC23_00200	COG0204	Acyl-transferase
ASC23_00215	COG0242	peptide deformylase activity
ASC23_00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC23_00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC23_00260	COG2813	Specifically methylates the guanine in position
ASC23_00270	COG2223	nitrite transmembrane transporter activity
ASC23_00280	COG1794	racemase activity, acting on amino acids and derivatives
ASC23_00285	COG1126	abc transporter atp-binding protein
ASC23_00290	COG0765	amino acid transport
ASC23_00295	COG0765	amino acid transport
ASC23_00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_00355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC23_00385	COG0326	Molecular chaperone. Has ATPase activity
ASC23_00390	COG0625	glutathione transferase activity
ASC23_00405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASC23_00410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASC23_00440	COG0438	transferase activity, transferring glycosyl groups
ASC23_00445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASC23_00450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASC23_00480	COG0859	PFAM glycosyl transferase family 9
ASC23_00495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ASC23_00505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASC23_00510	COG1127	ABC transporter
ASC23_00535	COG1686	Belongs to the peptidase S11 family
ASC23_00545	COG2921	Belongs to the UPF0250 family
ASC23_00550	COG0321	lipoyl(octanoyl) transferase activity
ASC23_00555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASC23_00590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASC23_00600	COG0018	arginyl-trna synthetase
ASC23_00620	COG0395	ABC-type sugar transport system, permease component
ASC23_00625	COG1175	transmembrane transport
ASC23_00630	COG1653	transport
ASC23_00635	COG3842	ATPase activity
ASC23_00640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASC23_00650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASC23_00670	COG1609	Transcriptional regulator
ASC23_00680	COG0154	amidase activity
ASC23_00685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASC23_00695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ASC23_00705	COG0583	DNA-binding transcription factor activity
ASC23_00720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC23_00725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASC23_00740	COG1802	Transcriptional regulator
ASC23_00755	COG1024	Enoyl-CoA hydratase
ASC23_00770	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_00785	COG1984	allophanate hydrolase subunit 2
ASC23_00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ASC23_00800	COG0583	DNA-binding transcription factor activity
ASC23_00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASC23_00815	COG5002	protein histidine kinase activity
ASC23_00825	COG5002	protein histidine kinase activity
ASC23_00830	COG0745	RESPONSE REGULATOR receiver
ASC23_00835	COG2226	methyltransferase
ASC23_00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASC23_00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASC23_00880	COG0513	Belongs to the DEAD box helicase family
ASC23_00885	COG1280	lysine exporter protein (LysE YggA)
ASC23_00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASC23_00930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASC23_00930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASC23_00940	COG0489	protein tyrosine kinase activity
ASC23_00955	COG0717	Belongs to the dCTP deaminase family
ASC23_00980	COG1982	Orn Lys Arg decarboxylase major
ASC23_00985	COG2081	HI0933 family
ASC23_00995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASC23_01005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASC23_01010	COG0509	glycine decarboxylation via glycine cleavage system
ASC23_01015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASC23_01015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASC23_01055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC23_01070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ASC23_01080	COG1414	Transcriptional regulator
ASC23_01085	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_01090	COG2031	fatty acid transporter
ASC23_01095	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC23_01105	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASC23_01110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASC23_01120	COG4257	antibiotic catabolic process
ASC23_01140	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_01145	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASC23_01150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASC23_01175	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_01185	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC23_01195	COG2188	Transcriptional regulator
ASC23_01200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC23_01225	COG0617	tRNA 3'-terminal CCA addition
ASC23_01240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASC23_01245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASC23_01250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASC23_01255	COG0586	Pfam SNARE associated Golgi protein
ASC23_01260	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASC23_01265	COG0802	atpase or kinase
ASC23_01270	COG0114	fumarate hydratase activity
ASC23_01280	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_01290	COG0405	Gamma-glutamyltransferase
ASC23_01295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_01330	COG1294	oxidase, subunit
ASC23_01340	COG4988	ABC transporter
ASC23_01345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASC23_01350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASC23_01390	COG2969	positive regulation of protein catabolic process
ASC23_01395	COG0625	glutathione transferase activity
ASC23_01400	COG2857	Cytochrome c1
ASC23_01405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASC23_01410	COG0723	plastoquinol--plastocyanin reductase activity
ASC23_01415	COG1970	mechanosensitive ion channel activity
ASC23_01420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASC23_01435	COG2808	Putative FMN-binding domain
ASC23_01440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASC23_01445	COG0747	negative chemotaxis
ASC23_01450	COG0657	acetylesterase activity
ASC23_01460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASC23_01465	COG2207	Transcriptional regulator
ASC23_01470	COG0129	dihydroxy-acid dehydratase activity
ASC23_01475	COG2814	Major facilitator Superfamily
ASC23_01480	COG0583	DNA-binding transcription factor activity
ASC23_01490	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ASC23_01530	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_01540	COG0411	ABC transporter
ASC23_01545	COG0410	ABC transporter
ASC23_01560	COG1024	Enoyl-CoA hydratase
ASC23_01565	COG1960	acyl-CoA dehydrogenase activity
ASC23_01590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASC23_01610	COG1678	Uncharacterized ACR, COG1678
ASC23_01615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASC23_01620	COG0540	Belongs to the ATCase OTCase family
ASC23_01635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASC23_01645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASC23_01680	COG1234	tRNA 3'-trailer cleavage
ASC23_01715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASC23_01730	COG1683	Conserved Protein
ASC23_01735	COG1120	ATPase activity
ASC23_01740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASC23_01745	COG4558	Periplasmic binding protein
ASC23_01750	COG3720	iron ion transport
ASC23_01760	COG3712	iron ion homeostasis
ASC23_01765	COG1595	DNA-templated transcription, initiation
ASC23_01800	COG1802	Transcriptional regulator
ASC23_01810	COG3069	C4-dicarboxylate transmembrane transporter activity
ASC23_01820	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_01855	COG2860	membrane
ASC23_01860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASC23_01865	COG0708	Exodeoxyribonuclease III
ASC23_01870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASC23_01875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASC23_01880	COG0154	amidase activity
ASC23_01885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASC23_01890	COG1077	Cell shape determining protein MreB Mrl
ASC23_01895	COG1792	Involved in formation and maintenance of cell shape
ASC23_01905	COG0768	penicillin binding
ASC23_01910	COG0772	Belongs to the SEDS family
ASC23_01915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASC23_01920	COG0471	metal ion transport
ASC23_01925	COG1309	transcriptional regulator
ASC23_01935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASC23_01950	COG2823	Periplasmic or secreted lipoprotein
ASC23_01955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASC23_01970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASC23_01990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_02025	COG0492	ferredoxin-NADP+ reductase activity
ASC23_02040	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC23_02040	COG1024	Enoyl-CoA hydratase
ASC23_02045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_02050	COG0028	Belongs to the TPP enzyme family
ASC23_02075	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_02085	COG0697	spore germination
ASC23_02110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ASC23_02115	COG0463	Glycosyl transferase, family 2
ASC23_02130	COG0786	glutamate:sodium symporter activity
ASC23_02140	COG2031	fatty acid transporter
ASC23_02155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASC23_02180	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_02190	COG0277	FAD linked oxidase domain protein
ASC23_02195	COG1960	acyl-CoA dehydrogenase activity
ASC23_02200	COG1960	acyl-CoA dehydrogenase activity
ASC23_02210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASC23_02225	COG2072	flavoprotein involved in K transport
ASC23_02230	COG0604	alcohol dehydrogenase
ASC23_02245	COG1024	Enoyl-CoA hydratase
ASC23_02265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASC23_02270	COG1522	sequence-specific DNA binding
ASC23_02275	COG0183	Belongs to the thiolase family
ASC23_02285	COG1960	acyl-CoA dehydrogenase activity
ASC23_02350	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_02360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASC23_02365	COG2890	protein-(glutamine-N5) methyltransferase activity
ASC23_02370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASC23_02375	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASC23_02395	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASC23_02410	COG2010	Cytochrome c
ASC23_02410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASC23_02415	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ASC23_02425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASC23_02430	COG1137	ATPase activity
ASC23_02445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASC23_02455	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASC23_02485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASC23_02490	COG3568	Endonuclease Exonuclease Phosphatase
ASC23_02495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC23_02525	COG0154	amidase activity
ASC23_02535	COG1414	Transcriptional regulator
ASC23_02550	COG1024	Enoyl-CoA hydratase
ASC23_02550	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC23_02560	COG2132	Multicopper oxidase
ASC23_02615	COG1024	Enoyl-CoA hydratase
ASC23_02620	COG1024	Enoyl-CoA hydratase
ASC23_02625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASC23_02645	COG0601	transmembrane transport
ASC23_02650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_02655	COG4172	Belongs to the ABC transporter superfamily
ASC23_02665	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASC23_02675	COG0210	DNA helicase
ASC23_02680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASC23_02685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASC23_02695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASC23_02700	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASC23_02705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASC23_02710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASC23_02715	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASC23_02720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASC23_02730	COG0356	it plays a direct role in the translocation of protons across the membrane
ASC23_02755	COG1024	Enoyl-CoA hydratase
ASC23_02760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASC23_02765	COG3634	alkyl hydroperoxide reductase activity
ASC23_02775	COG0037	tRNA processing
ASC23_02785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASC23_02790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASC23_02795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASC23_02800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASC23_02805	COG2967	ApaG domain
ASC23_02815	COG0546	phosphoglycolate phosphatase activity
ASC23_02825	COG0512	Glutamine amidotransferase of anthranilate synthase
ASC23_02830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASC23_02835	COG0134	indole-3-glycerol-phosphate synthase activity
ASC23_02865	COG0583	DNA-binding transcription factor activity
ASC23_02880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASC23_02885	COG0259	pyridoxamine-phosphate oxidase activity
ASC23_02895	COG2814	Major facilitator Superfamily
ASC23_02900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASC23_02905	COG2188	Transcriptional regulator
ASC23_02910	COG0318	PFAM AMP-dependent synthetase and ligase
ASC23_02930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASC23_02940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASC23_02955	COG1215	transferase activity, transferring glycosyl groups
ASC23_02965	COG0601	transmembrane transport
ASC23_02995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASC23_03000	COG2894	cell division
ASC23_03005	COG0850	regulation of cytokinetic process
ASC23_03010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASC23_03015	COG1271	oxidase subunit
ASC23_03030	COG0745	RESPONSE REGULATOR receiver
ASC23_03050	COG2979	Protein of unknown function (DUF533)
ASC23_03070	COG0741	lytic transglycosylase activity
ASC23_03070	COG1388	LysM domain
ASC23_03080	COG2226	methyltransferase
ASC23_03085	COG0328	RNA-DNA hybrid ribonuclease activity
ASC23_03160	COG0411	ABC transporter
ASC23_03180	COG1960	acyl-CoA dehydrogenase activity
ASC23_03195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_03215	COG2718	Belongs to the UPF0229 family
ASC23_03220	COG2719	SpoVR family
ASC23_03245	COG2188	Transcriptional regulator
ASC23_03270	COG0829	nickel cation binding
ASC23_03275	COG0831	urea catabolic process
ASC23_03285	COG0832	Belongs to the urease beta subunit family
ASC23_03290	COG0804	urea catabolic process
ASC23_03300	COG0830	nickel cation binding
ASC23_03305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASC23_03325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_03330	COG0601	transmembrane transport
ASC23_03335	COG0747	negative chemotaxis
ASC23_03350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC23_03360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASC23_03370	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ASC23_03375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASC23_03380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASC23_03395	COG0438	transferase activity, transferring glycosyl groups
ASC23_03410	COG0438	transferase activity, transferring glycosyl groups
ASC23_03415	COG0438	transferase activity, transferring glycosyl groups
ASC23_03420	COG0166	Belongs to the GPI family
ASC23_03435	COG0277	FAD linked oxidase domain protein
ASC23_03440	COG0745	RESPONSE REGULATOR receiver
ASC23_03445	COG0642	Histidine kinase
ASC23_03450	COG1368	sulfuric ester hydrolase activity
ASC23_03460	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ASC23_03485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASC23_03495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASC23_03500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASC23_03510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASC23_03515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASC23_03520	COG0193	aminoacyl-tRNA hydrolase activity
ASC23_03530	COG0012	GTP binding
ASC23_03535	COG0582	viral genome integration into host DNA
ASC23_03555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASC23_03605	COG0745	RESPONSE REGULATOR receiver
ASC23_03620	COG1309	transcriptional regulator
ASC23_03645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_03655	COG0405	Gamma-glutamyltransferase
ASC23_03730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASC23_03735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC23_03745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASC23_03750	COG0513	Belongs to the DEAD box helicase family
ASC23_03760	COG0617	tRNA 3'-terminal CCA addition
ASC23_03775	COG0477	Major facilitator Superfamily
ASC23_03785	COG0583	DNA-binding transcription factor activity
ASC23_03800	COG1950	PFAM Membrane protein of
ASC23_03805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ASC23_03820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASC23_03830	COG1560	Kdo2-lipid A biosynthetic process
ASC23_03835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASC23_03845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASC23_03855	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ASC23_03865	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASC23_03875	COG1121	(ABC) transporter
ASC23_03885	COG0735	belongs to the Fur family
ASC23_03890	COG0523	cobalamin synthesis protein
ASC23_03895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASC23_03900	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASC23_03905	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASC23_03915	COG2096	Adenosyltransferase
ASC23_03935	COG2084	Dehydrogenase
ASC23_03980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASC23_03985	COG0129	dihydroxy-acid dehydratase activity
ASC23_03990	COG4654	Cytochrome c, class I
ASC23_03995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASC23_04005	COG1522	sequence-specific DNA binding
ASC23_04045	COG1473	amidohydrolase
ASC23_04050	COG0418	dihydroorotase activity
ASC23_04060	COG2001	Belongs to the MraZ family
ASC23_04065	COG0275	rRNA processing
ASC23_04070	COG3116	cell division
ASC23_04080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASC23_04085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASC23_04090	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASC23_04100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASC23_04105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASC23_04110	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASC23_04115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASC23_04125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASC23_04130	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASC23_04140	COG0739	heme binding
ASC23_04145	COG0653	protein targeting
ASC23_04165	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_04170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_04175	COG1522	sequence-specific DNA binding
ASC23_04195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASC23_04205	COG0557	exoribonuclease II activity
ASC23_04210	COG3150	esterase
ASC23_04215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASC23_04220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASC23_04225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASC23_04230	COG0511	ligase activity, forming carbon-carbon bonds
ASC23_04235	COG0439	Biotin carboxylase
ASC23_04275	COG1696	Membrane protein involved in D-alanine export
ASC23_04280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASC23_04315	COG1522	sequence-specific DNA binding
ASC23_04330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASC23_04335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASC23_04335	COG1042	CoA-binding domain protein
ASC23_04335	COG0045	succinate-CoA ligase (ADP-forming) activity
ASC23_04345	COG1802	Transcriptional regulator
ASC23_04350	COG3069	C4-dicarboxylate transmembrane transporter activity
ASC23_04355	COG0513	Belongs to the DEAD box helicase family
ASC23_04360	COG0346	lactoylglutathione lyase activity
ASC23_04365	COG1335	isochorismatase
ASC23_04370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_04375	COG1116	anion transmembrane transporter activity
ASC23_04390	COG3028	Belongs to the UPF0307 family
ASC23_04395	COG0312	modulator of DNA gyrase
ASC23_04400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC23_04405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASC23_04410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASC23_04415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASC23_04425	COG0316	Belongs to the HesB IscA family
ASC23_04430	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASC23_04445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASC23_04455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASC23_04460	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASC23_04475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASC23_04475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASC23_04505	COG0583	DNA-binding transcription factor activity
ASC23_04545	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ASC23_04555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASC23_04560	COG1845	cytochrome c oxidase, subunit III
ASC23_04565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ASC23_04570	COG0640	Transcriptional regulator
ASC23_04590	COG3220	belongs to the UPF0276 family
ASC23_04665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASC23_04670	COG0312	modulator of DNA gyrase
ASC23_04675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASC23_04680	COG3064	Membrane
ASC23_04680	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC23_04680	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC23_04680	COG3210	domain, Protein
ASC23_04680	COG3210	domain, Protein
ASC23_04680	COG3064	Membrane
ASC23_04685	COG0277	FAD linked oxidase domain protein
ASC23_04690	COG0277	FAD linked oxidase domain protein
ASC23_04695	COG0277	FAD linked oxidase domain protein
ASC23_04700	COG0247	lactate metabolic process
ASC23_04705	COG2819	hydrolase of the alpha beta superfamily
ASC23_04720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASC23_04725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASC23_04740	COG0583	DNA-binding transcription factor activity
ASC23_04745	COG0482	sulfurtransferase activity
ASC23_04750	COG0730	response to heat
ASC23_04755	COG0625	glutathione transferase activity
ASC23_04760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASC23_04765	COG3909	cytochrome
ASC23_04805	COG0154	amidase activity
ASC23_04810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_04815	COG1024	Enoyl-CoA hydratase
ASC23_04830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_04845	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_04850	COG1414	Transcriptional regulator
ASC23_04865	COG0251	oxidation-reduction process
ASC23_04870	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_04885	COG0410	ABC transporter
ASC23_04905	COG0583	DNA-binding transcription factor activity
ASC23_04915	COG0590	tRNA wobble adenosine to inosine editing
ASC23_04920	COG2807	transmembrane transport
ASC23_04940	COG0154	amidase activity
ASC23_04945	COG0307	riboflavin synthase, alpha
ASC23_04950	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_04955	COG1522	sequence-specific DNA binding
ASC23_04965	COG0318	PFAM AMP-dependent synthetase and ligase
ASC23_04975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_04995	COG1063	alcohol dehydrogenase
ASC23_05020	COG1418	mRNA catabolic process
ASC23_05025	COG1448	Aminotransferase
ASC23_05030	COG0583	DNA-binding transcription factor activity
ASC23_05040	COG0477	Major facilitator Superfamily
ASC23_05045	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_05060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC23_05065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASC23_05070	COG0583	DNA-binding transcription factor activity
ASC23_05110	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_05115	COG1309	transcriptional regulator
ASC23_05125	COG2982	Protein involved in outer membrane biogenesis
ASC23_05130	COG2818	Glycosylase
ASC23_05150	COG1653	transport
ASC23_05165	COG3842	ATPase activity
ASC23_05170	COG0395	ABC-type sugar transport system, permease component
ASC23_05175	COG1175	transmembrane transport
ASC23_05200	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_05205	COG2186	Transcriptional regulator
ASC23_05230	COG1454	alcohol dehydrogenase
ASC23_05250	COG2011	ABC-type metal ion transport system permease component
ASC23_05255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASC23_05260	COG1501	Belongs to the glycosyl hydrolase 31 family
ASC23_05280	COG0318	PFAM AMP-dependent synthetase and ligase
ASC23_05285	COG1473	amidohydrolase
ASC23_05295	COG2855	membrane
ASC23_05300	COG1607	acyl-coa hydrolase
ASC23_05305	COG2239	Acts as a magnesium transporter
ASC23_05325	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_05335	COG1722	exodeoxyribonuclease VII activity
ASC23_05340	COG0142	geranyltranstransferase activity
ASC23_05345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASC23_05350	COG1469	GTP cyclohydrolase I activity
ASC23_05355	COG0360	Binds together with S18 to 16S ribosomal RNA
ASC23_05360	COG2965	DNA replication, synthesis of RNA primer
ASC23_05365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASC23_05370	COG0359	binds to the 23S rRNA
ASC23_05380	COG0305	Participates in initiation and elongation during chromosome replication
ASC23_05390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASC23_05395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASC23_05400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASC23_05405	COG3737	Protein of unknown function (DUF498/DUF598)
ASC23_05410	COG0436	Aminotransferase
ASC23_05435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASC23_05465	COG0268	Binds directly to 16S ribosomal RNA
ASC23_05475	COG0728	peptidoglycan biosynthetic process
ASC23_05485	COG0563	adenylate kinase activity
ASC23_05490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASC23_05495	COG2835	tetraacyldisaccharide 4'-kinase activity
ASC23_05500	COG1663	tetraacyldisaccharide 4'-kinase activity
ASC23_05505	COG0848	biopolymer transport protein
ASC23_05510	COG0811	peptide transport
ASC23_05520	COG1570	exodeoxyribonuclease VII activity
ASC23_05525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASC23_05530	COG0038	chloride channel
ASC23_05535	COG0183	Belongs to the thiolase family
ASC23_05545	COG1278	Cold shock
ASC23_05550	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASC23_05560	COG4953	penicillin-binding protein 1C
ASC23_05565	COG0542	response to heat
ASC23_05570	COG2995	paraquat-inducible protein a
ASC23_05575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASC23_05575	COG3008	intermembrane lipid transfer
ASC23_05585	COG0506	proline dehydrogenase activity
ASC23_05585	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASC23_05585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASC23_05600	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_05620	COG2271	Major facilitator Superfamily
ASC23_05625	COG1309	transcriptional regulator
ASC23_05635	COG3468	outer membrane autotransporter barrel domain protein
ASC23_05665	COG0477	Major facilitator Superfamily
ASC23_05675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASC23_05680	COG1845	cytochrome c oxidase, subunit III
ASC23_05685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ASC23_05695	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_05715	COG0789	Transcriptional regulator
ASC23_05740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASC23_05745	COG0697	spore germination
ASC23_05755	COG0678	peroxiredoxin activity
ASC23_05765	COG0412	Dienelactone hydrolase
ASC23_05775	COG0315	cyclic pyranopterin monophosphate synthase activity
ASC23_05790	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASC23_05795	COG0303	'Molybdopterin
ASC23_05800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASC23_05820	COG0165	Argininosuccinate lyase
ASC23_05825	COG0668	transmembrane transport
ASC23_05870	COG0747	negative chemotaxis
ASC23_05875	COG0601	transmembrane transport
ASC23_05885	COG1162	GTPase activity
ASC23_05890	COG0501	Belongs to the peptidase M48B family
ASC23_05895	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASC23_05905	COG3327	negative regulation of DNA-templated transcription, initiation
ASC23_05910	COG3396	Phenylacetate-CoA oxygenase
ASC23_05915	COG3460	Phenylacetate-CoA oxygenase
ASC23_05920	COG3396	Phenylacetate-CoA oxygenase
ASC23_05925	COG2151	metal-sulfur cluster biosynthetic enzyme
ASC23_05940	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_05945	COG1024	Enoyl-CoA hydratase
ASC23_05950	COG2050	protein possibly involved in aromatic compounds catabolism
ASC23_05960	COG3539	Fimbrial protein
ASC23_05975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC23_05980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASC23_05985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASC23_05990	COG0047	phosphoribosylformylglycinamidine synthase activity
ASC23_05990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASC23_05995	COG3064	Membrane
ASC23_05995	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC23_05995	COG3210	domain, Protein
ASC23_06020	COG0235	Class ii aldolase
ASC23_06025	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC23_06030	COG0720	synthase
ASC23_06035	COG0602	queuosine metabolic process
ASC23_06060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC23_06090	COG1053	succinate dehydrogenase
ASC23_06095	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_06125	COG3842	ATPase activity
ASC23_06135	COG0395	ABC-type sugar transport system, permease component
ASC23_06165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_06170	COG0420	3'-5' exonuclease activity
ASC23_06195	COG2197	response regulator
ASC23_06220	COG0519	Catalyzes the synthesis of GMP from XMP
ASC23_06220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASC23_06230	COG3550	peptidyl-serine autophosphorylation
ASC23_06240	COG0477	Major facilitator Superfamily
ASC23_06255	COG1228	amidohydrolase
ASC23_06265	COG1116	anion transmembrane transporter activity
ASC23_06270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_06305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASC23_06320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ASC23_06350	COG2814	Major facilitator Superfamily
ASC23_06365	COG1280	lysine exporter protein (LysE YggA)
ASC23_06380	COG0747	negative chemotaxis
ASC23_06385	COG0601	transmembrane transport
ASC23_06395	COG4172	Belongs to the ABC transporter superfamily
ASC23_06400	COG1609	Transcriptional regulator
ASC23_06425	COG0586	Pfam SNARE associated Golgi protein
ASC23_06435	COG0500	methyltransferase
ASC23_06450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC23_06460	COG0756	dUTP diphosphatase activity
ASC23_06475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASC23_06480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASC23_06485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASC23_06490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASC23_06490	COG0072	phenylalanine-tRNA ligase activity
ASC23_06495	COG0776	regulation of translation
ASC23_06565	COG0540	Belongs to the ATCase OTCase family
ASC23_06570	COG2974	May be involved in recombination
ASC23_06580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_06585	COG0583	DNA-binding transcription factor activity
ASC23_06605	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_06620	COG3842	ATPase activity
ASC23_06625	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC23_06625	COG1024	Enoyl-CoA hydratase
ASC23_06635	COG0642	Histidine kinase
ASC23_06645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASC23_06650	COG2137	regulation of response to DNA damage stimulus
ASC23_06655	COG0583	DNA-binding transcription factor activity
ASC23_06660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASC23_06670	COG0045	succinate-CoA ligase (ADP-forming) activity
ASC23_06675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASC23_06680	COG0861	Integral membrane protein TerC family
ASC23_06685	COG0861	Integral membrane protein TerC family
ASC23_06690	COG0181	hydroxymethylbilane synthase activity
ASC23_06710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASC23_06750	COG4964	Belongs to the GSP D family
ASC23_06780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASC23_06790	COG0583	DNA-binding transcription factor activity
ASC23_06800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_06805	COG4311	Sarcosine oxidase, delta subunit
ASC23_06810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASC23_06810	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASC23_06845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASC23_06850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASC23_06855	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASC23_06860	COG0735	belongs to the Fur family
ASC23_06865	COG0497	DNA recombination
ASC23_06870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASC23_06875	COG1420	regulation of RNA biosynthetic process
ASC23_06880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASC23_06890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASC23_06900	COG0443	Heat shock 70 kDa protein
ASC23_06910	COG0612	Peptidase, M16
ASC23_06930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASC23_06975	COG0745	RESPONSE REGULATOR receiver
ASC23_06980	COG2205	protein histidine kinase activity
ASC23_06985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ASC23_06990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ASC23_06995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ASC23_07005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASC23_07025	COG1193	negative regulation of DNA recombination
ASC23_07030	COG0492	ferredoxin-NADP+ reductase activity
ASC23_07035	COG1674	ftsk spoiiie
ASC23_07040	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASC23_07045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASC23_07050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASC23_07075	COG3706	GGDEF domain
ASC23_07095	COG2814	Major facilitator Superfamily
ASC23_07140	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_07150	COG3022	response to hydroperoxide
ASC23_07170	COG3706	GGDEF domain
ASC23_07180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASC23_07190	COG2197	response regulator
ASC23_07195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASC23_07200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASC23_07205	COG0189	ligase activity
ASC23_07215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASC23_07220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASC23_07230	COG2423	ornithine cyclodeaminase activity
ASC23_07240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_07245	COG0765	amino acid transport
ASC23_07250	COG0765	amino acid transport
ASC23_07255	COG1126	abc transporter atp-binding protein
ASC23_07310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASC23_07320	COG2944	sequence-specific DNA binding
ASC23_07325	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASC23_07330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASC23_07335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASC23_07340	COG0009	L-threonylcarbamoyladenylate synthase
ASC23_07345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_07350	COG1414	Transcriptional regulator
ASC23_07365	COG0765	amino acid transport
ASC23_07370	COG1126	abc transporter atp-binding protein
ASC23_07375	COG0028	Belongs to the TPP enzyme family
ASC23_07390	COG0028	Belongs to the TPP enzyme family
ASC23_07395	COG0583	DNA-binding transcription factor activity
ASC23_07400	COG4974	Belongs to the 'phage' integrase family
ASC23_07405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASC23_07410	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ASC23_07425	COG1686	Belongs to the peptidase S11 family
ASC23_07445	COG1074	ATP-dependent DNA helicase activity
ASC23_07450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASC23_07455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASC23_07460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASC23_07480	COG2321	neutral zinc metallopeptidase
ASC23_07485	COG0009	L-threonylcarbamoyladenylate synthase
ASC23_07530	COG3360	Dodecin
ASC23_07535	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASC23_07540	COG2850	peptidyl-arginine hydroxylation
ASC23_07545	COG3539	Fimbrial protein
ASC23_07550	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ASC23_07555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC23_07570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_07575	COG0765	amino acid transport
ASC23_07580	COG1126	abc transporter atp-binding protein
ASC23_07585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASC23_07590	COG1758	RNA polymerase activity
ASC23_07595	COG0194	GDP metabolic process
ASC23_07600	COG3258	Cytochrome c
ASC23_07605	COG2863	cytochrome
ASC23_07610	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_07615	COG0791	NLP P60 protein
ASC23_07620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASC23_07640	COG1561	YicC-like family, N-terminal region
ASC23_07645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASC23_07660	COG2200	EAL domain
ASC23_07660	COG2199	diguanylate cyclase activity
ASC23_07665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASC23_07675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASC23_07685	COG3852	Histidine kinase
ASC23_07690	COG2204	response regulator
ASC23_07695	COG0583	DNA-binding transcription factor activity
ASC23_07700	COG1741	Belongs to the pirin family
ASC23_07705	COG1741	Belongs to the pirin family
ASC23_07715	COG3842	ATPase activity
ASC23_07720	COG1178	ABC-type Fe3 transport system permease component
ASC23_07725	COG1840	ABC-type Fe3 transport system, periplasmic component
ASC23_07735	COG0583	DNA-binding transcription factor activity
ASC23_07745	COG0656	L-ascorbic acid biosynthetic process
ASC23_07760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASC23_07765	COG0583	DNA-binding transcription factor activity
ASC23_07780	COG0783	Belongs to the Dps family
ASC23_07815	COG0438	transferase activity, transferring glycosyl groups
ASC23_07830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASC23_07855	COG0300	oxidoreductase activity
ASC23_07900	COG0861	Integral membrane protein TerC family
ASC23_07905	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_07925	COG0714	Associated with various cellular activities
ASC23_07955	COG3119	arylsulfatase activity
ASC23_07980	COG2197	response regulator
ASC23_07990	COG2944	sequence-specific DNA binding
ASC23_08000	COG0625	glutathione transferase activity
ASC23_08030	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASC23_08035	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_08080	COG0431	NADPH-dependent FMN reductase
ASC23_08110	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_08115	COG0583	DNA-binding transcription factor activity
ASC23_08135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASC23_08135	COG2111	Na H antiporter
ASC23_08140	COG1006	Multisubunit Na H antiporter MnhC subunit
ASC23_08145	COG0651	ATP synthesis coupled electron transport
ASC23_08150	COG1863	multisubunit Na H antiporter MnhE subunit
ASC23_08155	COG2212	antiporter activity
ASC23_08180	COG0590	tRNA wobble adenosine to inosine editing
ASC23_08185	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASC23_08190	COG1024	Enoyl-CoA hydratase
ASC23_08205	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC23_08210	COG0488	(ABC) transporter
ASC23_08245	COG1017	nitric oxide dioxygenase activity
ASC23_08245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASC23_08250	COG1959	2 iron, 2 sulfur cluster binding
ASC23_08255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_08275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASC23_08280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASC23_08285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASC23_08290	COG0084	hydrolase, TatD family'
ASC23_08305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_08315	COG1126	abc transporter atp-binding protein
ASC23_08325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASC23_08340	COG0028	Belongs to the TPP enzyme family
ASC23_08360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC23_08400	COG4336	lyase activity
ASC23_08410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_08410	COG2205	protein histidine kinase activity
ASC23_08415	COG2197	response regulator
ASC23_08420	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC23_08420	COG3210	domain, Protein
ASC23_08420	COG3064	Membrane
ASC23_08430	COG3121	Chaperone
ASC23_08435	COG3188	usher protein
ASC23_08440	COG3539	Fimbrial protein
ASC23_08445	COG2831	hemolysin activation secretion protein
ASC23_08460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC23_08510	COG0668	transmembrane transport
ASC23_08535	COG1253	flavin adenine dinucleotide binding
ASC23_08540	COG1968	undecaprenyl-diphosphatase activity
ASC23_08545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASC23_08560	COG0215	cysteine-tRNA ligase activity
ASC23_08570	COG0825	malonyl-CoA metabolic process
ASC23_08580	COG0037	tRNA processing
ASC23_08585	COG0527	aspartate kinase activity
ASC23_08610	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC23_08615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASC23_08630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC23_08635	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ASC23_08640	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_08650	COG0583	DNA-binding transcription factor activity
ASC23_08670	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASC23_08680	COG3842	ATPase activity
ASC23_08690	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASC23_08690	COG1902	pentaerythritol trinitrate reductase activity
ASC23_08695	COG1414	Transcriptional regulator
ASC23_08700	COG1832	CoA-binding protein
ASC23_08710	COG0251	oxidation-reduction process
ASC23_08735	COG1902	pentaerythritol trinitrate reductase activity
ASC23_08745	COG1215	transferase activity, transferring glycosyl groups
ASC23_08750	COG1649	PFAM Uncharacterised BCR, COG1649
ASC23_08750	COG0726	polysaccharide deacetylase
ASC23_08770	COG1846	Transcriptional regulator
ASC23_08790	COG0166	Belongs to the GPI family
ASC23_08795	COG1045	serine acetyltransferase
ASC23_08805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASC23_08810	COG0483	inositol monophosphate 1-phosphatase activity
ASC23_08815	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_08820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASC23_08835	COG0210	DNA helicase
ASC23_08840	COG0598	Magnesium transport protein CorA
ASC23_08850	COG0747	negative chemotaxis
ASC23_08855	COG0601	transmembrane transport
ASC23_08860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_08865	COG4172	Belongs to the ABC transporter superfamily
ASC23_08870	COG1846	Transcriptional regulator
ASC23_08920	COG4964	Belongs to the GSP D family
ASC23_08960	COG2204	response regulator
ASC23_08975	COG1595	DNA-templated transcription, initiation
ASC23_08985	COG3474	cytochrome
ASC23_08990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASC23_09005	COG3384	dioxygenase
ASC23_09010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASC23_09035	COG2885	chlorophyll binding
ASC23_09070	COG0697	spore germination
ASC23_09075	COG0730	response to heat
ASC23_09090	COG0583	DNA-binding transcription factor activity
ASC23_09095	COG0427	acetyl-CoA hydrolase
ASC23_09140	COG3468	outer membrane autotransporter barrel domain protein
ASC23_09145	COG0424	maF-like protein
ASC23_09150	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASC23_09155	COG0799	negative regulation of ribosome biogenesis
ASC23_09160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASC23_09165	COG0408	coproporphyrinogen oxidase activity
ASC23_09170	COG0151	Belongs to the GarS family
ASC23_09175	COG0217	transcriptional regulatory protein
ASC23_09180	COG0433	COG0433 Predicted ATPase
ASC23_09185	COG1115	amino acid carrier protein
ASC23_09190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASC23_09200	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_09225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASC23_09240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_09250	COG0747	negative chemotaxis
ASC23_09260	COG0473	3-isopropylmalate dehydrogenase activity
ASC23_09265	COG2814	Major facilitator Superfamily
ASC23_09270	COG1566	PFAM secretion protein HlyD family protein
ASC23_09280	COG1846	Transcriptional regulator
ASC23_09290	COG0697	spore germination
ASC23_09300	COG0501	Belongs to the peptidase M48B family
ASC23_09320	COG0583	DNA-binding transcription factor activity
ASC23_09325	COG3842	ATPase activity
ASC23_09330	COG1178	ABC-type Fe3 transport system permease component
ASC23_09335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASC23_09340	COG1840	ABC-type Fe3 transport system, periplasmic component
ASC23_09345	COG0492	ferredoxin-NADP+ reductase activity
ASC23_09365	COG2233	PERMEase
ASC23_09370	COG0840	transmembrane signaling receptor activity
ASC23_09375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASC23_09405	COG4789	Type iii secretion
ASC23_09470	COG4669	(LipO)protein
ASC23_09500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASC23_09505	COG4790	Type iii secretion
ASC23_09510	COG4794	Type iii secretion
ASC23_09515	COG4791	protein targeting
ASC23_09520	COG4792	protein secretion
ASC23_09535	COG1595	DNA-templated transcription, initiation
ASC23_09555	COG2770	Histidine kinase
ASC23_09555	COG2208	phosphoserine phosphatase activity
ASC23_09565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASC23_09570	COG2172	sigma factor antagonist activity
ASC23_09575	COG1366	Belongs to the anti-sigma-factor antagonist family
ASC23_09580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC23_09615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASC23_09645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASC23_09655	COG2252	PERMEase
ASC23_09660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASC23_09670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASC23_09675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASC23_09680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASC23_09705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASC23_09710	COG0789	Transcriptional regulator
ASC23_09720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASC23_09720	COG0678	peroxiredoxin activity
ASC23_09730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASC23_09735	COG0584	glycerophosphoryl diester phosphodiesterase
ASC23_09740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASC23_09765	COG2823	Periplasmic or secreted lipoprotein
ASC23_09775	COG3237	CsbD-like
ASC23_09805	COG2833	Protein of unknown function (DUF455)
ASC23_09810	COG2951	lytic endotransglycosylase activity
ASC23_09825	COG1522	sequence-specific DNA binding
ASC23_09835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASC23_09840	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASC23_09845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASC23_09850	COG0196	riboflavin kinase activity
ASC23_09855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASC23_09855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASC23_09875	COG0210	DNA helicase
ASC23_09880	COG4771	TonB-dependent receptor
ASC23_09885	COG0488	(ABC) transporter
ASC23_09890	COG2890	protein-(glutamine-N5) methyltransferase activity
ASC23_09895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASC23_09900	COG2171	N-acyltransferase activity
ASC23_09935	COG1278	Cold shock
ASC23_09945	COG1278	Cold shock
ASC23_09955	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASC23_09960	COG0740	serine-type endopeptidase activity
ASC23_09965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASC23_09970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASC23_09975	COG0583	DNA-binding transcription factor activity
ASC23_09980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_09995	COG1024	Enoyl-CoA hydratase
ASC23_10005	COG0183	Belongs to the thiolase family
ASC23_10010	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_10030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ASC23_10055	COG3468	outer membrane autotransporter barrel domain protein
ASC23_10060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASC23_10070	COG0556	nucleotide-excision repair
ASC23_10075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASC23_10085	COG1104	cysteine desulfurase activity
ASC23_10090	COG0822	iron-sulfur transferase activity
ASC23_10095	COG0316	Belongs to the HesB IscA family
ASC23_10100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASC23_10105	COG0443	Heat shock 70 kDa protein
ASC23_10110	COG0633	Ferredoxin
ASC23_10130	COG1024	Enoyl-CoA hydratase
ASC23_10145	COG3395	kinase activity
ASC23_10150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASC23_10165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASC23_10175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_10200	COG0747	negative chemotaxis
ASC23_10205	COG0601	transmembrane transport
ASC23_10210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_10215	COG4172	Belongs to the ABC transporter superfamily
ASC23_10220	COG0154	amidase activity
ASC23_10265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASC23_10270	COG0425	Belongs to the sulfur carrier protein TusA family
ASC23_10280	COG0228	four-way junction DNA binding
ASC23_10285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASC23_10290	COG0336	Belongs to the RNA methyltransferase TrmD family
ASC23_10295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASC23_10315	COG0642	Histidine kinase
ASC23_10330	COG0525	valine-tRNA ligase activity
ASC23_10335	COG0105	UTP biosynthetic process
ASC23_10340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASC23_10350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASC23_10355	COG0124	histidyl-tRNA synthetase
ASC23_10360	COG2976	Protein conserved in bacteria
ASC23_10365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASC23_10370	COG1160	GTP binding
ASC23_10375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASC23_10380	COG1923	regulation of RNA biosynthetic process
ASC23_10385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASC23_10390	COG0330	HflC and HflK could
ASC23_10395	COG0330	HflC and HflK could
ASC23_10400	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ASC23_10405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASC23_10415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASC23_10425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASC23_10455	COG0628	permease
ASC23_10460	COG0842	Transport permease protein
ASC23_10465	COG1131	(ABC) transporter
ASC23_10535	COG0156	8-amino-7-oxononanoate synthase activity
ASC23_10545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASC23_10545	COG4106	trans-aconitate 2-methyltransferase activity
ASC23_10550	COG1380	Effector of murein hydrolase LrgA
ASC23_10555	COG1346	cytolysis
ASC23_10565	COG3284	Transcriptional regulator
ASC23_10570	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_10585	COG2733	membrane
ASC23_10590	COG0583	DNA-binding transcription factor activity
ASC23_10595	COG0384	phenazine biosynthesis protein PhzF
ASC23_10600	COG5507	3-demethylubiquinone-9 3-methyltransferase
ASC23_10605	COG2169	Transcriptional regulator
ASC23_10635	COG0659	secondary active sulfate transmembrane transporter activity
ASC23_10660	COG1132	(ABC) transporter
ASC23_10705	COG2207	Transcriptional regulator
ASC23_10835	COG2346	COG2346, Truncated hemoglobins
ASC23_10860	COG0583	DNA-binding transcription factor activity
ASC23_10865	COG4692	amylo-alpha-1,6-glucosidase activity
ASC23_10875	COG0183	Belongs to the thiolase family
ASC23_10890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_10895	COG0633	Ferredoxin
ASC23_10905	COG1024	Enoyl-CoA hydratase
ASC23_10910	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ASC23_10915	COG4638	Rieske (2fe-2S)
ASC23_10925	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_10945	COG2224	Isocitrate lyase
ASC23_10950	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASC23_10950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASC23_10965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASC23_10970	COG0322	excinuclease ABC activity
ASC23_10975	COG1472	Belongs to the glycosyl hydrolase 3 family
ASC23_10980	COG0736	holo-[acyl-carrier-protein] synthase activity
ASC23_10985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASC23_10995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASC23_11000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASC23_11025	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ASC23_11040	COG2032	superoxide dismutase activity
ASC23_11055	COG1024	Enoyl-CoA hydratase
ASC23_11065	COG1802	Transcriptional regulator
ASC23_11075	COG0183	Belongs to the thiolase family
ASC23_11080	COG1942	4-Oxalocrotonate Tautomerase
ASC23_11090	COG4176	ABC-type proline glycine betaine transport system permease component
ASC23_11110	COG2814	Major facilitator Superfamily
ASC23_11115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASC23_11120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASC23_11145	COG1846	Transcriptional regulator
ASC23_11150	COG2814	Major facilitator Superfamily
ASC23_11155	COG0495	leucyl-tRNA aminoacylation
ASC23_11170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASC23_11180	COG0154	amidase activity
ASC23_11185	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC23_11235	COG1530	ribonuclease E activity
ASC23_11240	COG0077	Prephenate dehydratase
ASC23_11255	COG1132	(ABC) transporter
ASC23_11260	COG0859	PFAM glycosyl transferase family 9
ASC23_11285	COG2194	sulfuric ester hydrolase activity
ASC23_11290	COG0438	transferase activity, transferring glycosyl groups
ASC23_11295	COG0463	Glycosyl transferase, family 2
ASC23_11300	COG0726	polysaccharide deacetylase
ASC23_11305	COG0438	transferase activity, transferring glycosyl groups
ASC23_11320	COG1643	Atp-dependent helicase
ASC23_11325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASC23_11325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASC23_11330	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ASC23_11340	COG0704	Plays a role in the regulation of phosphate uptake
ASC23_11345	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASC23_11350	COG1960	acyl-CoA dehydrogenase activity
ASC23_11365	COG2094	Belongs to the DNA glycosylase MPG family
ASC23_11375	COG1177	transmembrane transport
ASC23_11380	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASC23_11385	COG3842	ATPase activity
ASC23_11390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASC23_11395	COG3642	lipopolysaccharide core region biosynthetic process
ASC23_11405	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASC23_11410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC23_11440	COG0372	Belongs to the citrate synthase family
ASC23_11445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASC23_11450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASC23_11455	COG1053	succinate dehydrogenase
ASC23_11460	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASC23_11465	COG2009	succinate dehydrogenase
ASC23_11470	COG2188	Transcriptional regulator
ASC23_11475	COG0039	L-malate dehydrogenase activity
ASC23_11530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC23_11540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASC23_11570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASC23_11575	COG0148	phosphopyruvate hydratase activity
ASC23_11590	COG0504	CTP synthase activity
ASC23_11615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_11625	COG0747	negative chemotaxis
ASC23_11630	COG4172	Belongs to the ABC transporter superfamily
ASC23_11635	COG1446	asparaginase
ASC23_11665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASC23_11680	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASC23_11685	COG0697	spore germination
ASC23_11690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC23_11700	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ASC23_11705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC23_11710	COG0791	NLP P60 protein
ASC23_11725	COG0583	DNA-binding transcription factor activity
ASC23_11740	COG0583	DNA-binding transcription factor activity
ASC23_11750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASC23_11765	COG0670	Belongs to the BI1 family
ASC23_11770	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_11785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASC23_11795	COG1381	Involved in DNA repair and RecF pathway recombination
ASC23_11800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASC23_11805	COG0571	ribonuclease III activity
ASC23_11810	COG0681	Belongs to the peptidase S26 family
ASC23_11815	COG0481	GTPase activity
ASC23_11820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASC23_11845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASC23_11850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASC23_11865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASC23_11870	COG0416	fatty acid biosynthetic process
ASC23_11875	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASC23_11880	COG1399	metal-binding, possibly nucleic acid-binding protein
ASC23_11885	COG0424	maF-like protein
ASC23_11895	COG3023	N-Acetylmuramoyl-L-alanine amidase
ASC23_11910	COG3022	response to hydroperoxide
ASC23_11925	COG0135	phosphoribosylanthranilate isomerase activity
ASC23_11940	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC23_11945	COG0101	tRNA pseudouridine synthase activity
ASC23_11955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASC23_11960	COG0473	3-isopropylmalate dehydrogenase activity
ASC23_11965	COG0066	3-isopropylmalate dehydratase activity
ASC23_11970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASC23_11980	COG1122	ATPase activity
ASC23_12015	COG3383	formate dehydrogenase (NAD+) activity
ASC23_12015	COG0243	molybdopterin cofactor binding
ASC23_12045	COG0489	protein tyrosine kinase activity
ASC23_12050	COG0746	molybdenum cofactor guanylyltransferase activity
ASC23_12055	COG0303	'Molybdopterin
ASC23_12060	COG1763	Mo-molybdopterin cofactor biosynthetic process
ASC23_12065	COG4783	chaperone-mediated protein folding
ASC23_12070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASC23_12075	COG5001	Diguanylate cyclase
ASC23_12095	COG3842	ATPase activity
ASC23_12105	COG0406	alpha-ribazole phosphatase activity
ASC23_12115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASC23_12120	COG0505	Belongs to the CarA family
ASC23_12125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASC23_12155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ASC23_12160	COG1960	acyl-CoA dehydrogenase activity
ASC23_12170	COG2867	negative regulation of translational initiation
ASC23_12180	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASC23_12185	COG3706	GGDEF domain
ASC23_12190	COG0330	HflC and HflK could
ASC23_12205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASC23_12205	COG0519	Catalyzes the synthesis of GMP from XMP
ASC23_12215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASC23_12220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASC23_12225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASC23_12230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASC23_12240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASC23_12245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASC23_12250	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ASC23_12255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASC23_12260	COG0750	zinc metalloprotease
ASC23_12265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASC23_12275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASC23_12280	COG0233	cytoplasmic translational termination
ASC23_12285	COG0528	UMP kinase activity
ASC23_12290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASC23_12295	COG0052	Belongs to the universal ribosomal protein uS2 family
ASC23_12300	COG0024	Methionine aminopeptidase
ASC23_12305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASC23_12335	COG0285	dihydrofolate synthase activity
ASC23_12370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASC23_12380	COG1677	Flagellar hook-basal body complex protein FliE
ASC23_12390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASC23_12400	COG1157	protein secretion by the type III secretion system
ASC23_12425	COG1580	Controls the rotational direction of flagella during chemotaxis
ASC23_12445	COG1338	Plays a role in the flagellum-specific transport system
ASC23_12465	COG0840	transmembrane signaling receptor activity
ASC23_12470	COG0840	transmembrane signaling receptor activity
ASC23_12475	COG0840	transmembrane signaling receptor activity
ASC23_12485	COG1256	bacterial-type flagellum assembly
ASC23_12495	COG1706	bacterial-type flagellum-dependent cell motility
ASC23_12500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASC23_12505	COG4786	Flagellar basal body rod
ASC23_12515	COG1749	Flagellar hook protein flgE
ASC23_12520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ASC23_12525	COG1558	bacterial-type flagellum-dependent cell motility
ASC23_12530	COG1815	bacterial-type flagellum-dependent cell motility
ASC23_12570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_12580	COG1126	abc transporter atp-binding protein
ASC23_12595	COG4948	Mandelate Racemase Muconate Lactonizing
ASC23_12600	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_12610	COG0066	3-isopropylmalate dehydratase activity
ASC23_12625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_12635	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_12645	COG1802	Transcriptional regulator
ASC23_12660	COG0583	DNA-binding transcription factor activity
ASC23_12680	COG1695	Transcriptional regulator
ASC23_12685	COG3568	Endonuclease Exonuclease Phosphatase
ASC23_12690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC23_12745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASC23_12755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASC23_12765	COG1640	4-alpha-glucanotransferase
ASC23_12780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ASC23_12810	COG0667	Aldo Keto reductase
ASC23_12825	COG2259	Doxx family
ASC23_12855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_12875	COG0386	Belongs to the glutathione peroxidase family
ASC23_12880	COG0625	glutathione transferase activity
ASC23_12895	COG0095	Lipoate-protein ligase
ASC23_12935	COG2363	Small membrane protein
ASC23_12960	COG3842	ATPase activity
ASC23_12965	COG0395	ABC-type sugar transport system, permease component
ASC23_12970	COG1175	transmembrane transport
ASC23_12975	COG1653	transport
ASC23_12985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASC23_13000	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_13020	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASC23_13045	COG2311	Membrane
ASC23_13060	COG0187	DNA topoisomerase II activity
ASC23_13070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASC23_13080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASC23_13085	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASC23_13090	COG1760	l-serine dehydratase
ASC23_13095	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASC23_13100	COG0412	Dienelactone hydrolase
ASC23_13115	COG1611	Belongs to the LOG family
ASC23_13135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASC23_13140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASC23_13145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASC23_13150	COG2251	uridine kinase activity
ASC23_13150	COG0195	Participates in both transcription termination and antitermination
ASC23_13155	COG0779	Required for maturation of 30S ribosomal subunits
ASC23_13160	COG1187	pseudouridine synthase activity
ASC23_13165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASC23_13175	COG0583	DNA-binding transcription factor activity
ASC23_13185	COG0523	cobalamin synthesis protein
ASC23_13205	COG0625	glutathione transferase activity
ASC23_13215	COG1047	Peptidyl-prolyl cis-trans
ASC23_13220	COG2003	Belongs to the UPF0758 family
ASC23_13225	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ASC23_13230	COG3483	tryptophan 2,3-dioxygenase activity
ASC23_13235	COG0254	rRNA binding
ASC23_13245	COG0534	Mate efflux family protein
ASC23_13265	COG2304	oxidoreductase activity
ASC23_13285	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_13290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASC23_13295	COG1562	ergosterol biosynthetic process
ASC23_13300	COG1562	ergosterol biosynthetic process
ASC23_13305	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ASC23_13305	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ASC23_13310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASC23_13320	COG0842	Transport permease protein
ASC23_13325	COG1131	(ABC) transporter
ASC23_13345	COG1477	protein flavinylation
ASC23_13360	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ASC23_13375	COG5564	TIM-barrel signal transduction protein
ASC23_13380	COG5441	Belongs to the UPF0261 family
ASC23_13390	COG3468	outer membrane autotransporter barrel domain protein
ASC23_13405	COG0542	response to heat
ASC23_13410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASC23_13425	COG0494	nUDIX hydrolase
ASC23_13430	COG3530	Putative quorum-sensing-regulated virulence factor
ASC23_13440	COG1595	DNA-templated transcription, initiation
ASC23_13445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC23_13480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_13485	COG0765	amino acid transport
ASC23_13490	COG0765	amino acid transport
ASC23_13515	COG2988	succinylglutamate desuccinylase activity
ASC23_13540	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_13545	COG2084	Dehydrogenase
ASC23_13560	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASC23_13575	COG2814	Major facilitator Superfamily
ASC23_13585	COG0583	DNA-binding transcription factor activity
ASC23_13640	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ASC23_13645	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_13650	COG3243	poly(R)-hydroxyalkanoic acid synthase
ASC23_13660	COG0564	pseudouridine synthase activity
ASC23_13670	COG1199	ATP-dependent helicase activity
ASC23_13675	COG2183	response to ionizing radiation
ASC23_13680	COG0180	Tryptophanyl-tRNA synthetase
ASC23_13700	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_13710	COG0583	DNA-binding transcription factor activity
ASC23_13715	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_13720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASC23_13725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASC23_13730	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASC23_13735	COG0567	Dehydrogenase, E1 component
ASC23_13740	COG1297	OPT oligopeptide transporter protein
ASC23_13745	COG1297	OPT oligopeptide transporter protein
ASC23_13750	COG1522	sequence-specific DNA binding
ASC23_13760	COG0280	phosphate acetyltransferase
ASC23_13760	COG0281	malic enzyme
ASC23_13765	COG3539	Fimbrial protein
ASC23_13780	COG0613	PHP domain protein
ASC23_13815	COG0084	hydrolase, TatD family'
ASC23_13820	COG1136	(ABC) transporter
ASC23_13835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASC23_13840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASC23_13845	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_13850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASC23_13865	COG1022	Amp-dependent synthetase and ligase
ASC23_13900	COG2205	protein histidine kinase activity
ASC23_13905	COG0745	RESPONSE REGULATOR receiver
ASC23_13910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASC23_13920	COG1295	ribonuclease BN
ASC23_13935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASC23_13960	COG1534	Rna-binding protein
ASC23_13965	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASC23_13970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASC23_13980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASC23_13990	COG0248	Ppx GppA phosphatase
ASC23_14015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASC23_14030	COG2732	(Barnase) inhibitor
ASC23_14040	COG0281	malic enzyme
ASC23_14040	COG0280	phosphate acetyltransferase
ASC23_14050	COG0436	Aminotransferase
ASC23_14055	COG0741	lytic transglycosylase activity
ASC23_14060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASC23_14085	COG1648	precorrin-2 dehydrogenase activity
ASC23_14085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASC23_14090	COG3468	outer membrane autotransporter barrel domain protein
ASC23_14100	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASC23_14105	COG2027	D-alanyl-D-alanine carboxypeptidase
ASC23_14110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASC23_14115	COG0343	queuine tRNA-ribosyltransferase activity
ASC23_14120	COG1862	Preprotein translocase
ASC23_14125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASC23_14130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASC23_14145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASC23_14150	COG1702	phosphate starvation-inducible protein PhoH
ASC23_14155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASC23_14160	COG4535	Mg2 and Co2 transporter CorC
ASC23_14170	COG0667	Aldo Keto reductase
ASC23_14195	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ASC23_14200	COG0745	RESPONSE REGULATOR receiver
ASC23_14205	COG2201	protein-glutamate methylesterase activity
ASC23_14215	COG0840	transmembrane signaling receptor activity
ASC23_14220	COG0835	chemotaxis
ASC23_14225	COG0643	Histidine kinase
ASC23_14225	COG2198	Histidine kinase
ASC23_14255	COG1191	sigma factor activity
ASC23_14265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASC23_14275	COG0739	heme binding
ASC23_14285	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASC23_14295	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASC23_14325	COG0625	glutathione transferase activity
ASC23_14340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASC23_14345	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASC23_14350	COG0126	phosphoglycerate kinase activity
ASC23_14355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASC23_14360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASC23_14365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASC23_14375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASC23_14380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASC23_14385	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASC23_14390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASC23_14400	COG4566	intracellular signal transduction
ASC23_14410	COG0339	signal peptide processing
ASC23_14415	COG1999	signal sequence binding
ASC23_14425	COG1538	Outer membrane efflux protein
ASC23_14445	COG1187	pseudouridine synthase activity
ASC23_14450	COG3161	chorismate lyase activity
ASC23_14465	COG0667	Aldo Keto reductase
ASC23_14480	COG0335	large ribosomal subunit rRNA binding
ASC23_14515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASC23_14520	COG4208	sulfate ABC transporter
ASC23_14525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ASC23_14540	COG0450	alkyl hydroperoxide reductase
ASC23_14545	COG1960	acyl-CoA dehydrogenase activity
ASC23_14560	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASC23_14565	COG2951	lytic endotransglycosylase activity
ASC23_14580	COG1596	polysaccharide export
ASC23_14580	COG1555	photosystem II stabilization
ASC23_14585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASC23_14590	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ASC23_14595	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASC23_14615	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASC23_14620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASC23_14625	COG0287	Prephenate dehydrogenase
ASC23_14635	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASC23_14650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASC23_14660	COG2814	Major facilitator Superfamily
ASC23_14680	COG0583	DNA-binding transcription factor activity
ASC23_14715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASC23_14730	COG0667	Aldo Keto reductase
ASC23_14740	COG5265	(ABC) transporter
ASC23_14790	COG0439	Biotin carboxylase
ASC23_14795	COG2188	Transcriptional regulator
ASC23_14820	COG0511	ligase activity, forming carbon-carbon bonds
ASC23_14830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASC23_14850	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ASC23_14865	COG0500	methyltransferase
ASC23_14870	COG5265	(ABC) transporter
ASC23_14885	COG0028	Belongs to the TPP enzyme family
ASC23_14890	COG0440	acetolactate synthase activity
ASC23_14895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASC23_14900	COG1183	phosphatidylcholine synthase activity
ASC23_14910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASC23_14930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASC23_14950	COG0149	triose-phosphate isomerase activity
ASC23_14955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASC23_14965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASC23_14975	COG3799	methylaspartate ammonia-lyase activity
ASC23_15015	COG0583	DNA-binding transcription factor activity
ASC23_15020	COG0626	cystathionine gamma-synthase activity
ASC23_15025	COG3608	succinylglutamate desuccinylase aspartoacylase
ASC23_15045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_15065	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ASC23_15080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASC23_15085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASC23_15090	COG1733	regulation of RNA biosynthetic process
ASC23_15100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASC23_15105	COG0583	DNA-binding transcription factor activity
ASC23_15110	COG1597	lipid kinase activity
ASC23_15120	COG0671	phosphoesterase, PA-phosphatase related
ASC23_15145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC23_15150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC23_15155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC23_15160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC23_15165	COG0649	NAD binding
ASC23_15170	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ASC23_15180	COG1034	ATP synthesis coupled electron transport
ASC23_15185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASC23_15190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC23_15200	COG0713	ATP synthesis coupled electron transport
ASC23_15215	COG1007	ATP synthesis coupled electron transport
ASC23_15225	COG4774	siderophore transport
ASC23_15230	COG4774	siderophore transport
ASC23_15245	COG0028	Belongs to the TPP enzyme family
ASC23_15250	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_15255	COG0583	DNA-binding transcription factor activity
ASC23_15260	COG0560	Phosphoserine phosphatase
ASC23_15265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASC23_15270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASC23_15285	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ASC23_15290	COG0308	aminopeptidase N
ASC23_15310	COG0028	Belongs to the TPP enzyme family
ASC23_15320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASC23_15330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_15340	COG0318	PFAM AMP-dependent synthetase and ligase
ASC23_15350	COG1802	Transcriptional regulator
ASC23_15360	COG1802	Transcriptional regulator
ASC23_15370	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_15390	COG1126	abc transporter atp-binding protein
ASC23_15395	COG0765	amino acid transport
ASC23_15415	COG1538	Outer membrane efflux protein
ASC23_15420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASC23_15425	COG2274	protein secretion by the type I secretion system
ASC23_15430	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ASC23_15440	COG2994	toxin metabolic process
ASC23_15460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_15465	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ASC23_15475	COG0583	DNA-binding transcription factor activity
ASC23_15485	COG0142	geranyltranstransferase activity
ASC23_15495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASC23_15500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASC23_15505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASC23_15510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASC23_15550	COG3712	iron ion homeostasis
ASC23_15555	COG4774	siderophore transport
ASC23_15560	COG2353	YceI-like domain
ASC23_15580	COG0019	diaminopimelate decarboxylase activity
ASC23_15600	COG0747	negative chemotaxis
ASC23_15605	COG0601	transmembrane transport
ASC23_15610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_15620	COG0154	amidase activity
ASC23_15625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASC23_15650	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASC23_15660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ASC23_15670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASC23_15675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASC23_15680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASC23_15685	COG1929	Belongs to the glycerate kinase type-1 family
ASC23_15690	COG0469	pyruvate kinase activity
ASC23_15695	COG0700	Nucleoside recognition
ASC23_15725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASC23_15730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASC23_15745	COG0823	Involved in the tonB-independent uptake of proteins
ASC23_15755	COG0848	biopolymer transport protein
ASC23_15760	COG0811	peptide transport
ASC23_15765	COG0824	Thioesterase
ASC23_15770	COG0442	prolyl-tRNA aminoacylation
ASC23_15775	COG0494	nUDIX hydrolase
ASC23_15790	COG2135	peptidase activity
ASC23_15855	COG1196	nuclear chromosome segregation
ASC23_15995	COG1464	Belongs to the NlpA lipoprotein family
ASC23_16010	COG0410	ABC transporter
ASC23_16025	COG4211	Belongs to the binding-protein-dependent transport system permease family
ASC23_16030	COG0683	leucine binding
ASC23_16035	COG0154	amidase activity
ASC23_16040	COG0288	reversible hydration of carbon dioxide
ASC23_16055	COG0514	ATP-dependent DNA helicase (RecQ)
ASC23_16060	COG2255	four-way junction helicase activity
ASC23_16075	COG0632	four-way junction helicase activity
ASC23_16080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASC23_16100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASC23_16110	COG0006	proline dipeptidase activity
ASC23_16135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC23_16150	COG4783	chaperone-mediated protein folding
ASC23_16155	COG0429	hydrolase of the alpha beta-hydrolase fold
ASC23_16185	COG0513	Belongs to the DEAD box helicase family
ASC23_16205	COG1058	Belongs to the CinA family
ASC23_16205	COG1546	Belongs to the CinA family
ASC23_16210	COG1414	Transcriptional regulator
ASC23_16230	COG0167	dihydroorotate dehydrogenase activity
ASC23_16235	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASC23_16245	COG0583	DNA-binding transcription factor activity
ASC23_16305	COG0280	phosphate acetyltransferase
ASC23_16305	COG0281	malic enzyme
ASC23_16315	COG0601	transmembrane transport
ASC23_16320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_16325	COG4172	Belongs to the ABC transporter superfamily
ASC23_16355	COG0640	Transcriptional regulator
ASC23_16370	COG3135	benzoate transporter
ASC23_16375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASC23_16380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASC23_16385	COG0742	ribosomal rna small subunit methyltransferase
ASC23_16405	COG3639	organic phosphonate transmembrane transporter activity
ASC23_16410	COG3639	organic phosphonate transmembrane transporter activity
ASC23_16450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASC23_16455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASC23_16465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASC23_16470	COG1546	Belongs to the CinA family
ASC23_16470	COG1058	Belongs to the CinA family
ASC23_16475	COG0284	orotidine-5'-phosphate decarboxylase activity
ASC23_16480	COG1252	NADH dehydrogenase
ASC23_16495	COG3468	outer membrane autotransporter barrel domain protein
ASC23_16500	COG0459	protein refolding
ASC23_16505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASC23_16525	COG1053	succinate dehydrogenase
ASC23_16535	COG0583	DNA-binding transcription factor activity
ASC23_16555	COG3706	GGDEF domain
ASC23_16595	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ASC23_16605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC23_16615	COG0069	glutamate synthase activity
ASC23_16620	COG2391	methyltransferase activity
ASC23_16625	COG0679	Auxin Efflux Carrier
ASC23_16630	COG2153	protein acetylation
ASC23_16650	COG0557	exoribonuclease II activity
ASC23_16655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASC23_16665	COG3128	pkhd-type hydroxylase
ASC23_16670	COG0776	regulation of translation
ASC23_16695	COG0745	RESPONSE REGULATOR receiver
ASC23_16700	COG0642	Histidine kinase
ASC23_16705	COG3158	transport of potassium into the cell
ASC23_16710	COG0137	argininosuccinate synthase activity
ASC23_16715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASC23_16720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASC23_16730	COG0583	DNA-binding transcription factor activity
ASC23_16740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASC23_16760	COG2186	Transcriptional regulator
ASC23_16780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC23_16785	COG0450	alkyl hydroperoxide reductase
ASC23_16790	COG2205	protein histidine kinase activity
ASC23_16800	COG0745	RESPONSE REGULATOR receiver
ASC23_16805	COG1214	PFAM Peptidase M22, glycoprotease
ASC23_16810	COG1573	uracil-dna glycosylase
ASC23_16815	COG0477	Major facilitator Superfamily
ASC23_16820	COG1196	nuclear chromosome segregation
ASC23_16830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASC23_16850	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASC23_16855	COG1122	ATPase activity
ASC23_16860	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ASC23_16865	COG1268	BioY protein
ASC23_16880	COG0411	ABC transporter
ASC23_16885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASC23_16900	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_16915	COG0411	ABC transporter
ASC23_16920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASC23_16925	COG2878	Part of a membrane complex involved in electron transport
ASC23_16940	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASC23_16945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASC23_16950	COG0251	oxidation-reduction process
ASC23_16960	COG3228	Belongs to the MtfA family
ASC23_16965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASC23_16975	COG0133	tryptophan synthase activity
ASC23_16980	COG0159	tryptophan synthase activity
ASC23_17005	COG1530	ribonuclease E activity
ASC23_17015	COG0546	phosphoglycolate phosphatase activity
ASC23_17020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ASC23_17025	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ASC23_17035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_17040	COG0583	DNA-binding transcription factor activity
ASC23_17050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_17075	COG0251	oxidation-reduction process
ASC23_17080	COG1017	nitric oxide dioxygenase activity
ASC23_17080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASC23_17085	COG2031	fatty acid transporter
ASC23_17090	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_17095	COG1802	Transcriptional regulator
ASC23_17105	COG1278	Cold shock
ASC23_17110	COG0583	DNA-binding transcription factor activity
ASC23_17130	COG0183	Belongs to the thiolase family
ASC23_17140	COG1960	acyl-CoA dehydrogenase activity
ASC23_17145	COG0583	DNA-binding transcription factor activity
ASC23_17150	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_17155	COG1024	Enoyl-CoA hydratase
ASC23_17160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_17165	COG1253	flavin adenine dinucleotide binding
ASC23_17170	COG1285	pathogenesis
ASC23_17180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC23_17195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASC23_17205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC23_17215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_17220	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_17225	COG1960	acyl-CoA dehydrogenase activity
ASC23_17245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASC23_17250	COG1024	Enoyl-CoA hydratase
ASC23_17255	COG1960	acyl-CoA dehydrogenase activity
ASC23_17275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ASC23_17280	COG0022	dehydrogenase e1 component
ASC23_17285	COG1024	Enoyl-CoA hydratase
ASC23_17290	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASC23_17310	COG0683	leucine binding
ASC23_17315	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_17320	COG0411	ABC transporter
ASC23_17325	COG0410	ABC transporter
ASC23_17330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASC23_17345	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_17370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASC23_17375	COG0793	Belongs to the peptidase S41A family
ASC23_17380	COG4942	peptidase
ASC23_17385	COG0588	phosphoglycerate mutase activity
ASC23_17395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASC23_17400	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASC23_17405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASC23_17410	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_17425	COG2226	methyltransferase
ASC23_17430	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ASC23_17445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_17450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASC23_17475	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC23_17500	COG1335	isochorismatase
ASC23_17505	COG2309	aminopeptidase activity
ASC23_17515	COG3473	Maleate cis-trans isomerase
ASC23_17525	COG2068	MobA-Related Protein
ASC23_17545	COG0569	domain protein
ASC23_17550	COG2204	response regulator
ASC23_17555	COG5000	phosphorelay sensor kinase activity
ASC23_17565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASC23_17565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASC23_17575	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ASC23_17595	COG0583	DNA-binding transcription factor activity
ASC23_17615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC23_17620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_17635	COG0758	DNA mediated transformation
ASC23_17640	COG1522	sequence-specific DNA binding
ASC23_17650	COG0242	peptide deformylase activity
ASC23_17660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASC23_17670	COG0546	phosphoglycolate phosphatase activity
ASC23_17695	COG1942	4-Oxalocrotonate Tautomerase
ASC23_17700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC23_17720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASC23_17740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC23_17745	COG1024	Enoyl-CoA hydratase
ASC23_17750	COG1414	Transcriptional regulator
ASC23_17755	COG0318	PFAM AMP-dependent synthetase and ligase
ASC23_17760	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_17810	COG0330	HflC and HflK could
ASC23_17820	COG0251	oxidation-reduction process
ASC23_17865	COG3723	Recombinational DNA repair protein, rece pathway
ASC23_17900	COG0582	viral genome integration into host DNA
ASC23_17935	COG0706	membrane insertase activity
ASC23_17940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASC23_17945	COG0594	ribonuclease P activity
ASC23_17950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASC23_17970	COG1414	Transcriptional regulator
ASC23_17975	COG0154	amidase activity
ASC23_17990	COG1304	FMN binding
ASC23_18010	COG1960	acyl-CoA dehydrogenase activity
ASC23_18040	COG0183	Belongs to the thiolase family
ASC23_18045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASC23_18060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASC23_18065	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_18085	COG1629	transport
ASC23_18090	COG2922	Belongs to the Smg family
ASC23_18115	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASC23_18120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_18125	COG1028	Short-chain dehydrogenase reductase Sdr
ASC23_18130	COG1012	belongs to the aldehyde dehydrogenase family
ASC23_18140	COG0028	Belongs to the TPP enzyme family
ASC23_18145	COG1522	sequence-specific DNA binding
ASC23_18150	COG3781	membrane
ASC23_18160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASC23_18180	COG4206	TonB-dependent receptor
ASC23_18185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASC23_18190	COG2022	thiamine diphosphate biosynthetic process
ASC23_18195	COG0351	phosphomethylpyrimidine kinase
ASC23_18200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASC23_18215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASC23_18225	COG0628	permease
ASC23_18235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASC23_18245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASC23_18250	COG0049	tRNA binding
ASC23_18255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASC23_18260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASC23_18265	COG0051	transcription antitermination factor activity, RNA binding
ASC23_18270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASC23_18275	COG0088	Forms part of the polypeptide exit tunnel
ASC23_18280	COG0089	rRNA binding
ASC23_18285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASC23_18290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASC23_18295	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASC23_18300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASC23_18305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASC23_18310	COG0255	Belongs to the universal ribosomal protein uL29 family
ASC23_18315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASC23_18335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASC23_18340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASC23_18345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASC23_18350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASC23_18355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASC23_18360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASC23_18365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASC23_18370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASC23_18375	COG1841	ribosomal large subunit assembly
ASC23_18380	COG0200	Binds to the 23S rRNA
ASC23_18385	COG0201	protein transport
ASC23_18390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASC23_18395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASC23_18400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASC23_18405	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASC23_18410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASC23_18415	COG0202	RNA polymerase activity
ASC23_18420	COG0203	ribosomal protein L17
ASC23_18430	COG1324	tolerance protein
ASC23_18435	COG4232	protein-disulfide reductase activity
ASC23_18450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASC23_18460	COG1333	cytochrome c biogenesis protein
ASC23_18465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASC23_18475	COG1965	Belongs to the frataxin family
ASC23_18490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASC23_18495	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASC23_18510	COG2814	Major facilitator Superfamily
ASC23_18515	COG0629	single-stranded DNA binding
ASC23_18565	COG0438	transferase activity, transferring glycosyl groups
ASC23_18585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_18610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASC23_18635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC23_18640	COG1956	GAF domain-containing protein
ASC23_18645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC23_18655	COG1652	LysM domain
ASC23_18670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASC23_18685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASC23_18710	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_18725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_18740	COG1024	Enoyl-CoA hydratase
ASC23_18755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_18760	COG1309	transcriptional regulator
ASC23_18765	COG2816	NAD+ diphosphatase activity
ASC23_18770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASC23_18810	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC23_18855	COG2814	Major facilitator Superfamily
ASC23_18860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASC23_18880	COG1999	signal sequence binding
ASC23_18885	COG0109	protoheme IX farnesyltransferase activity
ASC23_18925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASC23_18945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASC23_18950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASC23_18960	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ASC23_18965	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ASC23_18975	COG0067	glutamate synthase
ASC23_18975	COG0070	glutamate synthase
ASC23_18975	COG0069	glutamate synthase activity
ASC23_18985	COG3047	cAMP biosynthetic process
ASC23_18995	COG1127	ABC transporter
ASC23_19000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASC23_19005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASC23_19010	COG2853	Lipoprotein
ASC23_19025	COG0842	Transport permease protein
ASC23_19035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASC23_19040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASC23_19045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASC23_19050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASC23_19055	COG0131	Imidazoleglycerol-phosphate dehydratase
ASC23_19060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASC23_19065	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASC23_19070	COG0107	imidazoleglycerol-phosphate synthase activity
ASC23_19075	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASC23_19085	COG0537	adenosine 5'-monophosphoramidase activity
ASC23_19090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASC23_19095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASC23_19110	COG3181	Tripartite tricarboxylate transporter family receptor
ASC23_19150	COG3451	type IV secretory pathway VirB4
ASC23_19170	COG3504	Conjugal transfer protein
ASC23_19175	COG2948	multi-organism process
ASC23_19190	COG0697	spore germination
ASC23_19210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASC23_19215	COG0747	negative chemotaxis
ASC23_19225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC23_19230	COG0444	Belongs to the ABC transporter superfamily
ASC23_19240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASC23_19250	COG0494	nUDIX hydrolase
ASC23_19270	COG1538	Outer membrane efflux protein
ASC23_19290	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ASC23_19295	COG0237	dephospho-CoA kinase activity
ASC23_19300	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASC23_19315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASC23_19320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ASC23_19330	COG0477	Major facilitator Superfamily
ASC23_19335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASC23_19350	COG1126	abc transporter atp-binding protein
ASC23_19355	COG0765	amino acid transport
ASC23_19360	COG4597	amino acid ABC transporter
ASC23_19365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC23_19370	COG2884	Cell division ATP-binding protein ftsE
ASC23_19375	COG2177	Part of the ABC transporter FtsEX involved in
ASC23_19380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ASC23_19390	COG1194	a g-specific adenine glycosylase
ASC23_19400	COG2226	methyltransferase
ASC23_19410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_19415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_19430	COG1024	Enoyl-CoA hydratase
ASC23_19450	COG1024	Enoyl-CoA hydratase
ASC23_19455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC23_19470	COG0753	catalase activity
ASC23_19475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC23_19480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASC23_19490	COG2175	clavaminate synthase activity
ASC23_19495	COG1473	amidohydrolase
ASC23_19500	COG4608	Belongs to the ABC transporter superfamily
ASC23_19505	COG0444	Belongs to the ABC transporter superfamily
ASC23_19515	COG0601	transmembrane transport
ASC23_19520	COG0747	negative chemotaxis
ASC23_19525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASC23_19540	COG3850	Histidine kinase
ASC23_19540	COG5002	protein histidine kinase activity
ASC23_19560	COG0436	Aminotransferase