locus-tag	class	description
ABC08_00005	COG0445	tRNA wobble uridine modification
ABC08_00015	COG1192	Involved in chromosome partitioning
ABC08_00025	COG1475	DNA binding
ABC08_00030	COG0252	asparaginase activity
ABC08_00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC08_00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC08_00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABC08_00080	COG0081	regulation of translation
ABC08_00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABC08_00090	COG0222	ribosome binding
ABC08_00095	COG0085	RNA polymerase activity
ABC08_00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABC08_00145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_00170	COG1024	Enoyl-CoA hydratase
ABC08_00190	COG0752	glycyl-tRNA synthetase alpha subunit
ABC08_00195	COG0751	glycine-tRNA ligase activity
ABC08_00200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABC08_00205	COG0204	Acyl-transferase
ABC08_00220	COG0242	peptide deformylase activity
ABC08_00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC08_00265	COG2813	Specifically methylates the guanine in position
ABC08_00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC08_00275	COG2223	nitrite transmembrane transporter activity
ABC08_00285	COG1794	racemase activity, acting on amino acids and derivatives
ABC08_00290	COG1126	abc transporter atp-binding protein
ABC08_00295	COG0765	amino acid transport
ABC08_00300	COG0765	amino acid transport
ABC08_00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_00360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC08_00385	COG0326	Molecular chaperone. Has ATPase activity
ABC08_00390	COG0625	glutathione transferase activity
ABC08_00405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC08_00410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABC08_00440	COG0438	transferase activity, transferring glycosyl groups
ABC08_00445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABC08_00450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABC08_00480	COG0859	PFAM glycosyl transferase family 9
ABC08_00495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABC08_00505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABC08_00510	COG1127	ABC transporter
ABC08_00535	COG1686	Belongs to the peptidase S11 family
ABC08_00545	COG2921	Belongs to the UPF0250 family
ABC08_00550	COG0321	lipoyl(octanoyl) transferase activity
ABC08_00555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABC08_00590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABC08_00600	COG0018	arginyl-trna synthetase
ABC08_00620	COG0395	ABC-type sugar transport system, permease component
ABC08_00625	COG1175	transmembrane transport
ABC08_00630	COG1653	transport
ABC08_00635	COG3842	ATPase activity
ABC08_00640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC08_00650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABC08_00670	COG1609	Transcriptional regulator
ABC08_00680	COG0154	amidase activity
ABC08_00685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC08_00695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABC08_00705	COG0583	DNA-binding transcription factor activity
ABC08_00720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC08_00725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC08_00740	COG1802	Transcriptional regulator
ABC08_00755	COG1024	Enoyl-CoA hydratase
ABC08_00770	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_00785	COG1984	allophanate hydrolase subunit 2
ABC08_00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABC08_00800	COG0583	DNA-binding transcription factor activity
ABC08_00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC08_00815	COG5002	protein histidine kinase activity
ABC08_00825	COG5002	protein histidine kinase activity
ABC08_00830	COG0745	RESPONSE REGULATOR receiver
ABC08_00835	COG2226	methyltransferase
ABC08_00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABC08_00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ABC08_00880	COG0513	Belongs to the DEAD box helicase family
ABC08_00885	COG1280	lysine exporter protein (LysE YggA)
ABC08_00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABC08_00930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC08_00930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC08_00940	COG0489	protein tyrosine kinase activity
ABC08_00955	COG0717	Belongs to the dCTP deaminase family
ABC08_00980	COG1982	Orn Lys Arg decarboxylase major
ABC08_00985	COG2081	HI0933 family
ABC08_00995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC08_01005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC08_01010	COG0509	glycine decarboxylation via glycine cleavage system
ABC08_01015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC08_01015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC08_01055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC08_01070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC08_01080	COG1414	Transcriptional regulator
ABC08_01085	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_01090	COG2031	fatty acid transporter
ABC08_01095	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC08_01105	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ABC08_01110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABC08_01120	COG4257	antibiotic catabolic process
ABC08_01140	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_01145	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABC08_01150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC08_01175	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_01185	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC08_01195	COG2188	Transcriptional regulator
ABC08_01200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC08_01225	COG0617	tRNA 3'-terminal CCA addition
ABC08_01240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABC08_01245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABC08_01250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABC08_01255	COG0586	Pfam SNARE associated Golgi protein
ABC08_01260	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC08_01265	COG0802	atpase or kinase
ABC08_01270	COG0114	fumarate hydratase activity
ABC08_01280	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_01290	COG0405	Gamma-glutamyltransferase
ABC08_01295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_01330	COG1294	oxidase, subunit
ABC08_01340	COG4988	ABC transporter
ABC08_01345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ABC08_01350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC08_01390	COG2969	positive regulation of protein catabolic process
ABC08_01395	COG0625	glutathione transferase activity
ABC08_01400	COG2857	Cytochrome c1
ABC08_01405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABC08_01410	COG0723	plastoquinol--plastocyanin reductase activity
ABC08_01415	COG1970	mechanosensitive ion channel activity
ABC08_01420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABC08_01435	COG2808	Putative FMN-binding domain
ABC08_01440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC08_01445	COG0747	negative chemotaxis
ABC08_01450	COG0657	acetylesterase activity
ABC08_01460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC08_01465	COG2207	Transcriptional regulator
ABC08_01470	COG0129	dihydroxy-acid dehydratase activity
ABC08_01475	COG2814	Major facilitator Superfamily
ABC08_01480	COG0583	DNA-binding transcription factor activity
ABC08_01490	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ABC08_01530	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_01540	COG0411	ABC transporter
ABC08_01545	COG0410	ABC transporter
ABC08_01560	COG1024	Enoyl-CoA hydratase
ABC08_01565	COG1960	acyl-CoA dehydrogenase activity
ABC08_01590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABC08_01610	COG1678	Uncharacterized ACR, COG1678
ABC08_01615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABC08_01620	COG0540	Belongs to the ATCase OTCase family
ABC08_01635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABC08_01645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC08_01680	COG1234	tRNA 3'-trailer cleavage
ABC08_01710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC08_01725	COG1683	Conserved Protein
ABC08_01730	COG1120	ATPase activity
ABC08_01735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC08_01740	COG4558	Periplasmic binding protein
ABC08_01745	COG3720	iron ion transport
ABC08_01755	COG3712	iron ion homeostasis
ABC08_01760	COG1595	DNA-templated transcription, initiation
ABC08_01795	COG1802	Transcriptional regulator
ABC08_01805	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC08_01815	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_01850	COG2860	membrane
ABC08_01855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC08_01860	COG0708	Exodeoxyribonuclease III
ABC08_01865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABC08_01870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC08_01875	COG0154	amidase activity
ABC08_01880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC08_01885	COG1077	Cell shape determining protein MreB Mrl
ABC08_01890	COG1792	Involved in formation and maintenance of cell shape
ABC08_01900	COG0768	penicillin binding
ABC08_01905	COG0772	Belongs to the SEDS family
ABC08_01910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC08_01915	COG0471	metal ion transport
ABC08_01920	COG1309	transcriptional regulator
ABC08_01930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC08_01945	COG2823	Periplasmic or secreted lipoprotein
ABC08_01950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABC08_01965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC08_01985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_01995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_02020	COG0492	ferredoxin-NADP+ reductase activity
ABC08_02035	COG1024	Enoyl-CoA hydratase
ABC08_02035	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC08_02040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_02045	COG0028	Belongs to the TPP enzyme family
ABC08_02070	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_02080	COG0697	spore germination
ABC08_02105	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ABC08_02110	COG0463	Glycosyl transferase, family 2
ABC08_02125	COG0786	glutamate:sodium symporter activity
ABC08_02135	COG2031	fatty acid transporter
ABC08_02150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABC08_02165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC08_02180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC08_02190	COG1285	pathogenesis
ABC08_02195	COG1253	flavin adenine dinucleotide binding
ABC08_02200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_02205	COG1024	Enoyl-CoA hydratase
ABC08_02210	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_02215	COG0583	DNA-binding transcription factor activity
ABC08_02220	COG1960	acyl-CoA dehydrogenase activity
ABC08_02230	COG0183	Belongs to the thiolase family
ABC08_02250	COG0583	DNA-binding transcription factor activity
ABC08_02255	COG1278	Cold shock
ABC08_02265	COG1802	Transcriptional regulator
ABC08_02270	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_02275	COG2031	fatty acid transporter
ABC08_02280	COG1017	nitric oxide dioxygenase activity
ABC08_02280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC08_02285	COG0251	oxidation-reduction process
ABC08_02310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_02320	COG0583	DNA-binding transcription factor activity
ABC08_02325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_02335	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ABC08_02340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABC08_02345	COG0546	phosphoglycolate phosphatase activity
ABC08_02355	COG1530	ribonuclease E activity
ABC08_02380	COG0159	tryptophan synthase activity
ABC08_02385	COG0133	tryptophan synthase activity
ABC08_02395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC08_02400	COG3228	Belongs to the MtfA family
ABC08_02410	COG0251	oxidation-reduction process
ABC08_02415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ABC08_02420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ABC08_02435	COG2878	Part of a membrane complex involved in electron transport
ABC08_02440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABC08_02445	COG0411	ABC transporter
ABC08_02460	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_02475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC08_02480	COG0411	ABC transporter
ABC08_02495	COG1268	BioY protein
ABC08_02500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABC08_02505	COG1122	ATPase activity
ABC08_02510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC08_02530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABC08_02540	COG1196	nuclear chromosome segregation
ABC08_02545	COG0477	Major facilitator Superfamily
ABC08_02550	COG1573	uracil-dna glycosylase
ABC08_02555	COG1214	PFAM Peptidase M22, glycoprotease
ABC08_02560	COG0745	RESPONSE REGULATOR receiver
ABC08_02570	COG2205	protein histidine kinase activity
ABC08_02575	COG0450	alkyl hydroperoxide reductase
ABC08_02580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC08_02600	COG2186	Transcriptional regulator
ABC08_02620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABC08_02630	COG0583	DNA-binding transcription factor activity
ABC08_02640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC08_02645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABC08_02650	COG0137	argininosuccinate synthase activity
ABC08_02655	COG3158	transport of potassium into the cell
ABC08_02660	COG0642	Histidine kinase
ABC08_02665	COG0745	RESPONSE REGULATOR receiver
ABC08_02690	COG0776	regulation of translation
ABC08_02695	COG3128	pkhd-type hydroxylase
ABC08_02705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC08_02710	COG0557	exoribonuclease II activity
ABC08_02730	COG2153	protein acetylation
ABC08_02735	COG0679	Auxin Efflux Carrier
ABC08_02740	COG2391	methyltransferase activity
ABC08_02745	COG0069	glutamate synthase activity
ABC08_02755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC08_02765	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ABC08_02805	COG3706	GGDEF domain
ABC08_02830	COG0583	DNA-binding transcription factor activity
ABC08_02840	COG1053	succinate dehydrogenase
ABC08_02860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABC08_02865	COG0459	protein refolding
ABC08_02870	COG3468	outer membrane autotransporter barrel domain protein
ABC08_02885	COG1252	NADH dehydrogenase
ABC08_02890	COG0284	orotidine-5'-phosphate decarboxylase activity
ABC08_02895	COG1058	Belongs to the CinA family
ABC08_02895	COG1546	Belongs to the CinA family
ABC08_02900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABC08_02910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC08_02915	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABC08_02955	COG3639	organic phosphonate transmembrane transporter activity
ABC08_02960	COG3639	organic phosphonate transmembrane transporter activity
ABC08_02980	COG0742	ribosomal rna small subunit methyltransferase
ABC08_02985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABC08_02990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABC08_02995	COG3135	benzoate transporter
ABC08_03010	COG0640	Transcriptional regulator
ABC08_03040	COG4172	Belongs to the ABC transporter superfamily
ABC08_03045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_03050	COG0601	transmembrane transport
ABC08_03060	COG0281	malic enzyme
ABC08_03060	COG0280	phosphate acetyltransferase
ABC08_03120	COG0583	DNA-binding transcription factor activity
ABC08_03130	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABC08_03135	COG0167	dihydroorotate dehydrogenase activity
ABC08_03155	COG1414	Transcriptional regulator
ABC08_03160	COG1546	Belongs to the CinA family
ABC08_03160	COG1058	Belongs to the CinA family
ABC08_03180	COG0513	Belongs to the DEAD box helicase family
ABC08_03210	COG0429	hydrolase of the alpha beta-hydrolase fold
ABC08_03215	COG4783	chaperone-mediated protein folding
ABC08_03230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC08_03255	COG0006	proline dipeptidase activity
ABC08_03265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC08_03285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ABC08_03290	COG0632	four-way junction helicase activity
ABC08_03305	COG2255	four-way junction helicase activity
ABC08_03310	COG0514	ATP-dependent DNA helicase (RecQ)
ABC08_03325	COG0288	reversible hydration of carbon dioxide
ABC08_03330	COG0154	amidase activity
ABC08_03335	COG0683	leucine binding
ABC08_03340	COG4211	Belongs to the binding-protein-dependent transport system permease family
ABC08_03355	COG0410	ABC transporter
ABC08_03370	COG1464	Belongs to the NlpA lipoprotein family
ABC08_03510	COG1196	nuclear chromosome segregation
ABC08_03575	COG2135	peptidase activity
ABC08_03590	COG0494	nUDIX hydrolase
ABC08_03595	COG0442	prolyl-tRNA aminoacylation
ABC08_03600	COG0824	Thioesterase
ABC08_03605	COG0811	peptide transport
ABC08_03610	COG0848	biopolymer transport protein
ABC08_03620	COG0823	Involved in the tonB-independent uptake of proteins
ABC08_03635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC08_03640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ABC08_03670	COG0700	Nucleoside recognition
ABC08_03675	COG0469	pyruvate kinase activity
ABC08_03680	COG1929	Belongs to the glycerate kinase type-1 family
ABC08_03685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABC08_03690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC08_03695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABC08_03705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABC08_03715	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABC08_03740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC08_03745	COG0154	amidase activity
ABC08_03755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_03760	COG0601	transmembrane transport
ABC08_03765	COG0747	negative chemotaxis
ABC08_03785	COG0019	diaminopimelate decarboxylase activity
ABC08_03805	COG2353	YceI-like domain
ABC08_03810	COG4774	siderophore transport
ABC08_03815	COG3712	iron ion homeostasis
ABC08_03855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABC08_03860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABC08_03865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABC08_03870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABC08_03880	COG0142	geranyltranstransferase activity
ABC08_03890	COG0583	DNA-binding transcription factor activity
ABC08_03900	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ABC08_03905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_03920	COG2994	toxin metabolic process
ABC08_03930	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ABC08_03935	COG2274	protein secretion by the type I secretion system
ABC08_03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC08_03945	COG1538	Outer membrane efflux protein
ABC08_03965	COG0765	amino acid transport
ABC08_03970	COG1126	abc transporter atp-binding protein
ABC08_03990	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_04000	COG1802	Transcriptional regulator
ABC08_04010	COG1802	Transcriptional regulator
ABC08_04020	COG0318	PFAM AMP-dependent synthetase and ligase
ABC08_04030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_04040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABC08_04050	COG0028	Belongs to the TPP enzyme family
ABC08_04070	COG0308	aminopeptidase N
ABC08_04075	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABC08_04090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABC08_04095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABC08_04100	COG0560	Phosphoserine phosphatase
ABC08_04105	COG0583	DNA-binding transcription factor activity
ABC08_04110	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_04115	COG0028	Belongs to the TPP enzyme family
ABC08_04130	COG4774	siderophore transport
ABC08_04135	COG4774	siderophore transport
ABC08_04145	COG1007	ATP synthesis coupled electron transport
ABC08_04160	COG0713	ATP synthesis coupled electron transport
ABC08_04170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC08_04175	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABC08_04180	COG1034	ATP synthesis coupled electron transport
ABC08_04190	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ABC08_04195	COG0649	NAD binding
ABC08_04200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC08_04205	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC08_04210	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC08_04215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC08_04240	COG0671	phosphoesterase, PA-phosphatase related
ABC08_04250	COG1597	lipid kinase activity
ABC08_04255	COG0583	DNA-binding transcription factor activity
ABC08_04260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC08_04270	COG1733	regulation of RNA biosynthetic process
ABC08_04275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC08_04280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC08_04295	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ABC08_04315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_04335	COG3608	succinylglutamate desuccinylase aspartoacylase
ABC08_04340	COG0626	cystathionine gamma-synthase activity
ABC08_04345	COG0583	DNA-binding transcription factor activity
ABC08_04385	COG3799	methylaspartate ammonia-lyase activity
ABC08_04395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC08_04405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC08_04410	COG0149	triose-phosphate isomerase activity
ABC08_04430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC08_04450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABC08_04460	COG1183	phosphatidylcholine synthase activity
ABC08_04465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABC08_04470	COG0440	acetolactate synthase activity
ABC08_04475	COG0028	Belongs to the TPP enzyme family
ABC08_04490	COG5265	(ABC) transporter
ABC08_04495	COG0500	methyltransferase
ABC08_04510	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ABC08_04530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABC08_04540	COG0511	ligase activity, forming carbon-carbon bonds
ABC08_04565	COG2188	Transcriptional regulator
ABC08_04570	COG0439	Biotin carboxylase
ABC08_04620	COG5265	(ABC) transporter
ABC08_04630	COG0667	Aldo Keto reductase
ABC08_04645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABC08_04680	COG0583	DNA-binding transcription factor activity
ABC08_04700	COG2814	Major facilitator Superfamily
ABC08_04710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABC08_04725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABC08_04735	COG0287	Prephenate dehydrogenase
ABC08_04740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABC08_04745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABC08_04765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ABC08_04775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABC08_04780	COG1555	photosystem II stabilization
ABC08_04780	COG1596	polysaccharide export
ABC08_04795	COG2951	lytic endotransglycosylase activity
ABC08_04800	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABC08_04815	COG1960	acyl-CoA dehydrogenase activity
ABC08_04820	COG0450	alkyl hydroperoxide reductase
ABC08_04835	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABC08_04840	COG4208	sulfate ABC transporter
ABC08_04845	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABC08_04880	COG0335	large ribosomal subunit rRNA binding
ABC08_04895	COG0667	Aldo Keto reductase
ABC08_04910	COG3161	chorismate lyase activity
ABC08_04915	COG1187	pseudouridine synthase activity
ABC08_04935	COG1538	Outer membrane efflux protein
ABC08_04945	COG1999	signal sequence binding
ABC08_04950	COG0339	signal peptide processing
ABC08_04960	COG4566	intracellular signal transduction
ABC08_04970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABC08_04975	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC08_04980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC08_04985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABC08_04995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABC08_05000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABC08_05005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABC08_05010	COG0126	phosphoglycerate kinase activity
ABC08_05015	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABC08_05020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABC08_05035	COG0625	glutathione transferase activity
ABC08_05065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABC08_05075	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABC08_05085	COG0739	heme binding
ABC08_05095	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC08_05105	COG1191	sigma factor activity
ABC08_05135	COG0643	Histidine kinase
ABC08_05135	COG2198	Histidine kinase
ABC08_05140	COG0835	chemotaxis
ABC08_05145	COG0840	transmembrane signaling receptor activity
ABC08_05155	COG2201	protein-glutamate methylesterase activity
ABC08_05160	COG0745	RESPONSE REGULATOR receiver
ABC08_05165	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ABC08_05190	COG0667	Aldo Keto reductase
ABC08_05200	COG4535	Mg2 and Co2 transporter CorC
ABC08_05205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABC08_05210	COG1702	phosphate starvation-inducible protein PhoH
ABC08_05215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC08_05230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC08_05235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC08_05240	COG1862	Preprotein translocase
ABC08_05245	COG0343	queuine tRNA-ribosyltransferase activity
ABC08_05250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABC08_05255	COG2027	D-alanyl-D-alanine carboxypeptidase
ABC08_05260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABC08_05285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABC08_05285	COG1648	precorrin-2 dehydrogenase activity
ABC08_05310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABC08_05315	COG0741	lytic transglycosylase activity
ABC08_05320	COG0436	Aminotransferase
ABC08_05330	COG0281	malic enzyme
ABC08_05330	COG0280	phosphate acetyltransferase
ABC08_05340	COG2732	(Barnase) inhibitor
ABC08_05355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABC08_05380	COG0248	Ppx GppA phosphatase
ABC08_05390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABC08_05400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC08_05405	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ABC08_05410	COG1534	Rna-binding protein
ABC08_05435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABC08_05450	COG1295	ribonuclease BN
ABC08_05460	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABC08_05465	COG0745	RESPONSE REGULATOR receiver
ABC08_05470	COG2205	protein histidine kinase activity
ABC08_05505	COG1022	Amp-dependent synthetase and ligase
ABC08_05520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABC08_05525	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_05530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABC08_05535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABC08_05550	COG1136	(ABC) transporter
ABC08_05555	COG0084	hydrolase, TatD family'
ABC08_05590	COG0613	PHP domain protein
ABC08_05605	COG3539	Fimbrial protein
ABC08_05610	COG0280	phosphate acetyltransferase
ABC08_05610	COG0281	malic enzyme
ABC08_05620	COG1522	sequence-specific DNA binding
ABC08_05625	COG1297	OPT oligopeptide transporter protein
ABC08_05630	COG1297	OPT oligopeptide transporter protein
ABC08_05635	COG0567	Dehydrogenase, E1 component
ABC08_05640	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC08_05645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC08_05650	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABC08_05655	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_05660	COG0583	DNA-binding transcription factor activity
ABC08_05670	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_05690	COG0180	Tryptophanyl-tRNA synthetase
ABC08_05695	COG2183	response to ionizing radiation
ABC08_05700	COG1199	ATP-dependent helicase activity
ABC08_05710	COG0564	pseudouridine synthase activity
ABC08_05720	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABC08_05725	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_05730	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ABC08_05785	COG0583	DNA-binding transcription factor activity
ABC08_05795	COG2814	Major facilitator Superfamily
ABC08_05810	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC08_05825	COG2084	Dehydrogenase
ABC08_05830	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_05855	COG2988	succinylglutamate desuccinylase activity
ABC08_05880	COG0765	amino acid transport
ABC08_05885	COG0765	amino acid transport
ABC08_05890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_05925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC08_05930	COG1595	DNA-templated transcription, initiation
ABC08_05940	COG3530	Putative quorum-sensing-regulated virulence factor
ABC08_05945	COG0494	nUDIX hydrolase
ABC08_05960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABC08_05965	COG0542	response to heat
ABC08_05980	COG3468	outer membrane autotransporter barrel domain protein
ABC08_05990	COG5441	Belongs to the UPF0261 family
ABC08_05995	COG5564	TIM-barrel signal transduction protein
ABC08_06010	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ABC08_06025	COG1477	protein flavinylation
ABC08_06045	COG1131	(ABC) transporter
ABC08_06050	COG0842	Transport permease protein
ABC08_06060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABC08_06065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABC08_06065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABC08_06070	COG1562	ergosterol biosynthetic process
ABC08_06075	COG1562	ergosterol biosynthetic process
ABC08_06080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC08_06085	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_06105	COG2304	oxidoreductase activity
ABC08_06125	COG0534	Mate efflux family protein
ABC08_06135	COG0254	rRNA binding
ABC08_06140	COG3483	tryptophan 2,3-dioxygenase activity
ABC08_06145	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABC08_06150	COG2003	Belongs to the UPF0758 family
ABC08_06155	COG1047	Peptidyl-prolyl cis-trans
ABC08_06165	COG0625	glutathione transferase activity
ABC08_06185	COG0523	cobalamin synthesis protein
ABC08_06195	COG0583	DNA-binding transcription factor activity
ABC08_06205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABC08_06210	COG1187	pseudouridine synthase activity
ABC08_06215	COG0779	Required for maturation of 30S ribosomal subunits
ABC08_06220	COG2251	uridine kinase activity
ABC08_06220	COG0195	Participates in both transcription termination and antitermination
ABC08_06225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABC08_06230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABC08_06235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABC08_06255	COG1611	Belongs to the LOG family
ABC08_06270	COG0412	Dienelactone hydrolase
ABC08_06275	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABC08_06280	COG1760	l-serine dehydratase
ABC08_06285	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABC08_06290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ABC08_06300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABC08_06310	COG0187	DNA topoisomerase II activity
ABC08_06325	COG2311	Membrane
ABC08_06350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABC08_06370	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_06385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ABC08_06395	COG1653	transport
ABC08_06400	COG1175	transmembrane transport
ABC08_06405	COG0395	ABC-type sugar transport system, permease component
ABC08_06410	COG3842	ATPase activity
ABC08_06435	COG2363	Small membrane protein
ABC08_06475	COG0095	Lipoate-protein ligase
ABC08_06490	COG0625	glutathione transferase activity
ABC08_06495	COG0386	Belongs to the glutathione peroxidase family
ABC08_06515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_06545	COG2259	Doxx family
ABC08_06560	COG0667	Aldo Keto reductase
ABC08_06590	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ABC08_06615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ABC08_06625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ABC08_06680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC08_06685	COG3568	Endonuclease Exonuclease Phosphatase
ABC08_06690	COG1695	Transcriptional regulator
ABC08_06710	COG0583	DNA-binding transcription factor activity
ABC08_06725	COG1802	Transcriptional regulator
ABC08_06735	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_06745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_06760	COG0066	3-isopropylmalate dehydratase activity
ABC08_06770	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_06775	COG4948	Mandelate Racemase Muconate Lactonizing
ABC08_06790	COG1126	abc transporter atp-binding protein
ABC08_06800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_06840	COG1815	bacterial-type flagellum-dependent cell motility
ABC08_06845	COG1558	bacterial-type flagellum-dependent cell motility
ABC08_06850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ABC08_06855	COG1749	Flagellar hook protein flgE
ABC08_06865	COG4786	Flagellar basal body rod
ABC08_06870	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABC08_06875	COG1706	bacterial-type flagellum-dependent cell motility
ABC08_06885	COG1256	bacterial-type flagellum assembly
ABC08_06895	COG0840	transmembrane signaling receptor activity
ABC08_06900	COG0840	transmembrane signaling receptor activity
ABC08_06905	COG0840	transmembrane signaling receptor activity
ABC08_06925	COG1338	Plays a role in the flagellum-specific transport system
ABC08_06945	COG1580	Controls the rotational direction of flagella during chemotaxis
ABC08_06970	COG1157	protein secretion by the type III secretion system
ABC08_06975	COG1317	bacterial-type flagellum organization
ABC08_06980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC08_06990	COG1677	Flagellar hook-basal body complex protein FliE
ABC08_07000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC08_07035	COG0285	dihydrofolate synthase activity
ABC08_07065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABC08_07070	COG0024	Methionine aminopeptidase
ABC08_07075	COG0052	Belongs to the universal ribosomal protein uS2 family
ABC08_07080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABC08_07085	COG0528	UMP kinase activity
ABC08_07090	COG0233	cytoplasmic translational termination
ABC08_07095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABC08_07105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABC08_07110	COG0750	zinc metalloprotease
ABC08_07115	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC08_07120	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ABC08_07125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC08_07130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABC08_07140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC08_07145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABC08_07150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC08_07155	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABC08_07165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC08_07165	COG0519	Catalyzes the synthesis of GMP from XMP
ABC08_07180	COG0330	HflC and HflK could
ABC08_07185	COG3706	GGDEF domain
ABC08_07190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABC08_07200	COG2867	negative regulation of translational initiation
ABC08_07210	COG1960	acyl-CoA dehydrogenase activity
ABC08_07215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ABC08_07245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABC08_07250	COG0505	Belongs to the CarA family
ABC08_07255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC08_07265	COG0406	alpha-ribazole phosphatase activity
ABC08_07275	COG3842	ATPase activity
ABC08_07295	COG5001	Diguanylate cyclase
ABC08_07300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABC08_07305	COG4783	chaperone-mediated protein folding
ABC08_07310	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABC08_07315	COG0303	'Molybdopterin
ABC08_07320	COG0746	molybdenum cofactor guanylyltransferase activity
ABC08_07325	COG0489	protein tyrosine kinase activity
ABC08_07355	COG3383	formate dehydrogenase (NAD+) activity
ABC08_07355	COG0243	molybdopterin cofactor binding
ABC08_07390	COG1122	ATPase activity
ABC08_07400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABC08_07405	COG0066	3-isopropylmalate dehydratase activity
ABC08_07410	COG0473	3-isopropylmalate dehydrogenase activity
ABC08_07415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABC08_07425	COG0101	tRNA pseudouridine synthase activity
ABC08_07430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC08_07445	COG0135	phosphoribosylanthranilate isomerase activity
ABC08_07460	COG3022	response to hydroperoxide
ABC08_07480	COG3706	GGDEF domain
ABC08_07490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC08_07500	COG2197	response regulator
ABC08_07505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABC08_07510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABC08_07515	COG0189	ligase activity
ABC08_07525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC08_07530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABC08_07540	COG2423	ornithine cyclodeaminase activity
ABC08_07550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_07555	COG0765	amino acid transport
ABC08_07560	COG0765	amino acid transport
ABC08_07565	COG1126	abc transporter atp-binding protein
ABC08_07620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABC08_07630	COG2944	sequence-specific DNA binding
ABC08_07635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABC08_07640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABC08_07645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABC08_07650	COG0009	L-threonylcarbamoyladenylate synthase
ABC08_07655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_07660	COG1414	Transcriptional regulator
ABC08_07675	COG0765	amino acid transport
ABC08_07680	COG1126	abc transporter atp-binding protein
ABC08_07685	COG0028	Belongs to the TPP enzyme family
ABC08_07700	COG0028	Belongs to the TPP enzyme family
ABC08_07705	COG0583	DNA-binding transcription factor activity
ABC08_07710	COG4974	Belongs to the 'phage' integrase family
ABC08_07715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABC08_07720	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ABC08_07735	COG1686	Belongs to the peptidase S11 family
ABC08_07755	COG1074	ATP-dependent DNA helicase activity
ABC08_07760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC08_07765	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABC08_07770	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABC08_07790	COG2321	neutral zinc metallopeptidase
ABC08_07795	COG0009	L-threonylcarbamoyladenylate synthase
ABC08_07835	COG3360	Dodecin
ABC08_07840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABC08_07845	COG2850	peptidyl-arginine hydroxylation
ABC08_07850	COG3539	Fimbrial protein
ABC08_07855	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ABC08_07860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC08_07875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_07880	COG0765	amino acid transport
ABC08_07885	COG1126	abc transporter atp-binding protein
ABC08_07890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC08_07895	COG1758	RNA polymerase activity
ABC08_07900	COG0194	GDP metabolic process
ABC08_07905	COG3258	Cytochrome c
ABC08_07910	COG2863	cytochrome
ABC08_07915	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_07920	COG0791	NLP P60 protein
ABC08_07925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABC08_07945	COG1561	YicC-like family, N-terminal region
ABC08_07950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABC08_07965	COG2199	diguanylate cyclase activity
ABC08_07965	COG2200	EAL domain
ABC08_07970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABC08_07980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC08_07990	COG3852	Histidine kinase
ABC08_07995	COG2204	response regulator
ABC08_08000	COG0583	DNA-binding transcription factor activity
ABC08_08005	COG1741	Belongs to the pirin family
ABC08_08010	COG1741	Belongs to the pirin family
ABC08_08020	COG3842	ATPase activity
ABC08_08025	COG1178	ABC-type Fe3 transport system permease component
ABC08_08030	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC08_08040	COG0583	DNA-binding transcription factor activity
ABC08_08050	COG0656	L-ascorbic acid biosynthetic process
ABC08_08065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABC08_08070	COG0583	DNA-binding transcription factor activity
ABC08_08085	COG0783	Belongs to the Dps family
ABC08_08120	COG0438	transferase activity, transferring glycosyl groups
ABC08_08135	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC08_08160	COG0300	oxidoreductase activity
ABC08_08205	COG0861	Integral membrane protein TerC family
ABC08_08210	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_08230	COG0714	Associated with various cellular activities
ABC08_08260	COG3119	arylsulfatase activity
ABC08_08285	COG2197	response regulator
ABC08_08295	COG2944	sequence-specific DNA binding
ABC08_08305	COG0625	glutathione transferase activity
ABC08_08335	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC08_08340	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_08385	COG0431	NADPH-dependent FMN reductase
ABC08_08415	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_08420	COG0583	DNA-binding transcription factor activity
ABC08_08440	COG2111	Na H antiporter
ABC08_08440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABC08_08445	COG1006	Multisubunit Na H antiporter MnhC subunit
ABC08_08450	COG0651	ATP synthesis coupled electron transport
ABC08_08455	COG1863	multisubunit Na H antiporter MnhE subunit
ABC08_08460	COG2212	antiporter activity
ABC08_08485	COG0590	tRNA wobble adenosine to inosine editing
ABC08_08490	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC08_08495	COG1024	Enoyl-CoA hydratase
ABC08_08510	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC08_08515	COG0488	(ABC) transporter
ABC08_08550	COG1017	nitric oxide dioxygenase activity
ABC08_08550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC08_08555	COG1959	2 iron, 2 sulfur cluster binding
ABC08_08560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_08580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABC08_08585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABC08_08590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC08_08595	COG0084	hydrolase, TatD family'
ABC08_08610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_08620	COG1126	abc transporter atp-binding protein
ABC08_08630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC08_08645	COG0028	Belongs to the TPP enzyme family
ABC08_08665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC08_08705	COG4336	lyase activity
ABC08_08715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_08715	COG2205	protein histidine kinase activity
ABC08_08720	COG2197	response regulator
ABC08_08725	COG3064	Membrane
ABC08_08725	COG3210	domain, Protein
ABC08_08725	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC08_08735	COG3121	Chaperone
ABC08_08740	COG3188	usher protein
ABC08_08745	COG3539	Fimbrial protein
ABC08_08750	COG2831	hemolysin activation secretion protein
ABC08_08765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC08_08815	COG0668	transmembrane transport
ABC08_08840	COG1253	flavin adenine dinucleotide binding
ABC08_08845	COG1968	undecaprenyl-diphosphatase activity
ABC08_08850	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC08_08865	COG0215	cysteine-tRNA ligase activity
ABC08_08875	COG0825	malonyl-CoA metabolic process
ABC08_08885	COG0037	tRNA processing
ABC08_08890	COG0527	aspartate kinase activity
ABC08_08915	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC08_08920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC08_08935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC08_08940	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ABC08_08945	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_08955	COG0583	DNA-binding transcription factor activity
ABC08_08975	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABC08_08985	COG3842	ATPase activity
ABC08_08995	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC08_08995	COG1902	pentaerythritol trinitrate reductase activity
ABC08_09000	COG1414	Transcriptional regulator
ABC08_09005	COG1832	CoA-binding protein
ABC08_09015	COG0251	oxidation-reduction process
ABC08_09040	COG1902	pentaerythritol trinitrate reductase activity
ABC08_09050	COG1215	transferase activity, transferring glycosyl groups
ABC08_09055	COG0726	polysaccharide deacetylase
ABC08_09055	COG1649	PFAM Uncharacterised BCR, COG1649
ABC08_09075	COG1846	Transcriptional regulator
ABC08_09095	COG0166	Belongs to the GPI family
ABC08_09100	COG1045	serine acetyltransferase
ABC08_09110	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABC08_09115	COG0483	inositol monophosphate 1-phosphatase activity
ABC08_09120	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_09125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC08_09140	COG0210	DNA helicase
ABC08_09145	COG0598	Magnesium transport protein CorA
ABC08_09155	COG0747	negative chemotaxis
ABC08_09160	COG0601	transmembrane transport
ABC08_09165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_09170	COG4172	Belongs to the ABC transporter superfamily
ABC08_09175	COG1846	Transcriptional regulator
ABC08_09225	COG4964	Belongs to the GSP D family
ABC08_09265	COG2204	response regulator
ABC08_09280	COG1595	DNA-templated transcription, initiation
ABC08_09290	COG3474	cytochrome
ABC08_09295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABC08_09310	COG3384	dioxygenase
ABC08_09315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABC08_09340	COG2885	chlorophyll binding
ABC08_09375	COG0697	spore germination
ABC08_09380	COG0730	response to heat
ABC08_09395	COG0583	DNA-binding transcription factor activity
ABC08_09400	COG0427	acetyl-CoA hydrolase
ABC08_09455	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC08_09460	COG0154	amidase activity
ABC08_09470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABC08_09485	COG0495	leucyl-tRNA aminoacylation
ABC08_09490	COG2814	Major facilitator Superfamily
ABC08_09495	COG1846	Transcriptional regulator
ABC08_09520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABC08_09525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABC08_09530	COG2814	Major facilitator Superfamily
ABC08_09550	COG4176	ABC-type proline glycine betaine transport system permease component
ABC08_09560	COG1942	4-Oxalocrotonate Tautomerase
ABC08_09565	COG0183	Belongs to the thiolase family
ABC08_09575	COG1802	Transcriptional regulator
ABC08_09585	COG1024	Enoyl-CoA hydratase
ABC08_09600	COG2032	superoxide dismutase activity
ABC08_09615	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABC08_09640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC08_09645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC08_09655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABC08_09660	COG0736	holo-[acyl-carrier-protein] synthase activity
ABC08_09665	COG1472	Belongs to the glycosyl hydrolase 3 family
ABC08_09670	COG0322	excinuclease ABC activity
ABC08_09675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABC08_09690	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC08_09690	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC08_09695	COG2224	Isocitrate lyase
ABC08_09715	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_09725	COG4638	Rieske (2fe-2S)
ABC08_09730	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ABC08_09735	COG1024	Enoyl-CoA hydratase
ABC08_09745	COG0633	Ferredoxin
ABC08_09750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_09765	COG0183	Belongs to the thiolase family
ABC08_09775	COG4692	amylo-alpha-1,6-glucosidase activity
ABC08_09780	COG0583	DNA-binding transcription factor activity
ABC08_09805	COG2346	COG2346, Truncated hemoglobins
ABC08_09935	COG2207	Transcriptional regulator
ABC08_09980	COG1132	(ABC) transporter
ABC08_10005	COG0659	secondary active sulfate transmembrane transporter activity
ABC08_10035	COG2169	Transcriptional regulator
ABC08_10040	COG5507	3-demethylubiquinone-9 3-methyltransferase
ABC08_10045	COG0384	phenazine biosynthesis protein PhzF
ABC08_10050	COG0583	DNA-binding transcription factor activity
ABC08_10055	COG2733	membrane
ABC08_10070	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_10075	COG3284	Transcriptional regulator
ABC08_10090	COG1346	cytolysis
ABC08_10095	COG1380	Effector of murein hydrolase LrgA
ABC08_10100	COG4106	trans-aconitate 2-methyltransferase activity
ABC08_10100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABC08_10110	COG0156	8-amino-7-oxononanoate synthase activity
ABC08_10180	COG1131	(ABC) transporter
ABC08_10185	COG0842	Transport permease protein
ABC08_10190	COG0628	permease
ABC08_10220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC08_10230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABC08_10240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABC08_10245	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABC08_10250	COG0330	HflC and HflK could
ABC08_10255	COG0330	HflC and HflK could
ABC08_10260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABC08_10265	COG1923	regulation of RNA biosynthetic process
ABC08_10270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC08_10275	COG1160	GTP binding
ABC08_10280	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC08_10285	COG2976	Protein conserved in bacteria
ABC08_10290	COG0124	histidyl-tRNA synthetase
ABC08_10295	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABC08_10305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABC08_10310	COG0105	UTP biosynthetic process
ABC08_10315	COG0525	valine-tRNA ligase activity
ABC08_10330	COG0642	Histidine kinase
ABC08_10350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABC08_10355	COG0336	Belongs to the RNA methyltransferase TrmD family
ABC08_10360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABC08_10365	COG0228	four-way junction DNA binding
ABC08_10375	COG0425	Belongs to the sulfur carrier protein TusA family
ABC08_10380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABC08_10425	COG0154	amidase activity
ABC08_10430	COG4172	Belongs to the ABC transporter superfamily
ABC08_10435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_10440	COG0601	transmembrane transport
ABC08_10445	COG0747	negative chemotaxis
ABC08_10470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_10480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABC08_10495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC08_10500	COG3395	kinase activity
ABC08_10515	COG1024	Enoyl-CoA hydratase
ABC08_10535	COG0633	Ferredoxin
ABC08_10540	COG0443	Heat shock 70 kDa protein
ABC08_10545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABC08_10550	COG0316	Belongs to the HesB IscA family
ABC08_10555	COG0822	iron-sulfur transferase activity
ABC08_10560	COG1104	cysteine desulfurase activity
ABC08_10570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABC08_10575	COG0556	nucleotide-excision repair
ABC08_10585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABC08_10590	COG3468	outer membrane autotransporter barrel domain protein
ABC08_10615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC08_10635	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_10640	COG0183	Belongs to the thiolase family
ABC08_10650	COG1024	Enoyl-CoA hydratase
ABC08_10665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_10670	COG0583	DNA-binding transcription factor activity
ABC08_10675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABC08_10680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABC08_10685	COG0740	serine-type endopeptidase activity
ABC08_10690	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABC08_10700	COG1278	Cold shock
ABC08_10710	COG1278	Cold shock
ABC08_10745	COG2171	N-acyltransferase activity
ABC08_10750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC08_10755	COG2890	protein-(glutamine-N5) methyltransferase activity
ABC08_10760	COG0488	(ABC) transporter
ABC08_10765	COG4771	TonB-dependent receptor
ABC08_10770	COG0210	DNA helicase
ABC08_10790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC08_10790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABC08_10795	COG0196	riboflavin kinase activity
ABC08_10800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABC08_10805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABC08_10810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABC08_10820	COG1522	sequence-specific DNA binding
ABC08_10840	COG2951	lytic endotransglycosylase activity
ABC08_10845	COG2833	Protein of unknown function (DUF455)
ABC08_10875	COG3237	CsbD-like
ABC08_10885	COG2823	Periplasmic or secreted lipoprotein
ABC08_10910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC08_10915	COG0584	glycerophosphoryl diester phosphodiesterase
ABC08_10920	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABC08_10930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABC08_10930	COG0678	peroxiredoxin activity
ABC08_10940	COG0789	Transcriptional regulator
ABC08_10945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABC08_10970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABC08_10975	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABC08_10980	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABC08_10990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABC08_10995	COG2252	PERMEase
ABC08_11005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC08_11035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC08_11070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC08_11075	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC08_11080	COG2172	sigma factor antagonist activity
ABC08_11085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC08_11095	COG2770	Histidine kinase
ABC08_11095	COG2208	phosphoserine phosphatase activity
ABC08_11120	COG1595	DNA-templated transcription, initiation
ABC08_11135	COG4792	protein secretion
ABC08_11140	COG4791	protein targeting
ABC08_11145	COG4794	Type iii secretion
ABC08_11150	COG4790	Type iii secretion
ABC08_11155	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC08_11185	COG4669	(LipO)protein
ABC08_11250	COG4789	Type iii secretion
ABC08_11280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABC08_11285	COG0840	transmembrane signaling receptor activity
ABC08_11290	COG2233	PERMEase
ABC08_11315	COG0492	ferredoxin-NADP+ reductase activity
ABC08_11320	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC08_11325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABC08_11330	COG1178	ABC-type Fe3 transport system permease component
ABC08_11335	COG3842	ATPase activity
ABC08_11340	COG0583	DNA-binding transcription factor activity
ABC08_11360	COG0501	Belongs to the peptidase M48B family
ABC08_11370	COG0697	spore germination
ABC08_11380	COG1846	Transcriptional regulator
ABC08_11390	COG1566	PFAM secretion protein HlyD family protein
ABC08_11395	COG2814	Major facilitator Superfamily
ABC08_11400	COG0473	3-isopropylmalate dehydrogenase activity
ABC08_11410	COG0747	negative chemotaxis
ABC08_11420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_11435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC08_11460	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_11470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC08_11475	COG1115	amino acid carrier protein
ABC08_11480	COG0433	COG0433 Predicted ATPase
ABC08_11485	COG0217	transcriptional regulatory protein
ABC08_11490	COG0151	Belongs to the GarS family
ABC08_11495	COG0408	coproporphyrinogen oxidase activity
ABC08_11500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABC08_11505	COG0799	negative regulation of ribosome biogenesis
ABC08_11510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABC08_11515	COG0424	maF-like protein
ABC08_11520	COG3468	outer membrane autotransporter barrel domain protein
ABC08_11555	COG1530	ribonuclease E activity
ABC08_11560	COG0077	Prephenate dehydratase
ABC08_11575	COG1132	(ABC) transporter
ABC08_11580	COG0859	PFAM glycosyl transferase family 9
ABC08_11605	COG2194	sulfuric ester hydrolase activity
ABC08_11610	COG0438	transferase activity, transferring glycosyl groups
ABC08_11615	COG0463	Glycosyl transferase, family 2
ABC08_11620	COG0726	polysaccharide deacetylase
ABC08_11625	COG0438	transferase activity, transferring glycosyl groups
ABC08_11640	COG1643	Atp-dependent helicase
ABC08_11645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ABC08_11645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC08_11650	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ABC08_11660	COG0704	Plays a role in the regulation of phosphate uptake
ABC08_11665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABC08_11670	COG1960	acyl-CoA dehydrogenase activity
ABC08_11685	COG2094	Belongs to the DNA glycosylase MPG family
ABC08_11695	COG1177	transmembrane transport
ABC08_11700	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABC08_11705	COG3842	ATPase activity
ABC08_11710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABC08_11715	COG3642	lipopolysaccharide core region biosynthetic process
ABC08_11725	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABC08_11730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC08_11760	COG0372	Belongs to the citrate synthase family
ABC08_11765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ABC08_11770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABC08_11775	COG1053	succinate dehydrogenase
ABC08_11780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABC08_11785	COG2009	succinate dehydrogenase
ABC08_11790	COG2188	Transcriptional regulator
ABC08_11795	COG0039	L-malate dehydrogenase activity
ABC08_11850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC08_11860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABC08_11890	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABC08_11895	COG0148	phosphopyruvate hydratase activity
ABC08_11910	COG0504	CTP synthase activity
ABC08_11935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_11945	COG0747	negative chemotaxis
ABC08_11950	COG4172	Belongs to the ABC transporter superfamily
ABC08_11955	COG1446	asparaginase
ABC08_11985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABC08_12000	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ABC08_12005	COG0697	spore germination
ABC08_12010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC08_12020	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ABC08_12025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC08_12030	COG0791	NLP P60 protein
ABC08_12045	COG0583	DNA-binding transcription factor activity
ABC08_12060	COG0583	DNA-binding transcription factor activity
ABC08_12070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABC08_12085	COG0670	Belongs to the BI1 family
ABC08_12090	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_12105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC08_12115	COG1381	Involved in DNA repair and RecF pathway recombination
ABC08_12120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABC08_12125	COG0571	ribonuclease III activity
ABC08_12130	COG0681	Belongs to the peptidase S26 family
ABC08_12135	COG0481	GTPase activity
ABC08_12140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC08_12165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABC08_12170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABC08_12185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC08_12190	COG0416	fatty acid biosynthetic process
ABC08_12195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABC08_12200	COG1399	metal-binding, possibly nucleic acid-binding protein
ABC08_12205	COG0424	maF-like protein
ABC08_12215	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABC08_12230	COG3022	response to hydroperoxide
ABC08_12240	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_12285	COG2814	Major facilitator Superfamily
ABC08_12305	COG3706	GGDEF domain
ABC08_12330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABC08_12335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABC08_12340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABC08_12345	COG1674	ftsk spoiiie
ABC08_12350	COG0492	ferredoxin-NADP+ reductase activity
ABC08_12355	COG1193	negative regulation of DNA recombination
ABC08_12375	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC08_12385	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABC08_12390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABC08_12395	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ABC08_12400	COG2205	protein histidine kinase activity
ABC08_12405	COG0745	RESPONSE REGULATOR receiver
ABC08_12450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC08_12470	COG0612	Peptidase, M16
ABC08_12480	COG0443	Heat shock 70 kDa protein
ABC08_12490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABC08_12500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABC08_12505	COG1420	regulation of RNA biosynthetic process
ABC08_12510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABC08_12515	COG0497	DNA recombination
ABC08_12520	COG0735	belongs to the Fur family
ABC08_12525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC08_12530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABC08_12535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABC08_12570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC08_12570	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC08_12575	COG4311	Sarcosine oxidase, delta subunit
ABC08_12580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_12590	COG0583	DNA-binding transcription factor activity
ABC08_12600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABC08_12630	COG4964	Belongs to the GSP D family
ABC08_12670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ABC08_12690	COG0181	hydroxymethylbilane synthase activity
ABC08_12700	COG0861	Integral membrane protein TerC family
ABC08_12705	COG0861	Integral membrane protein TerC family
ABC08_12710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABC08_12715	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC08_12725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABC08_12730	COG0583	DNA-binding transcription factor activity
ABC08_12735	COG2137	regulation of response to DNA damage stimulus
ABC08_12740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABC08_12750	COG0642	Histidine kinase
ABC08_12760	COG1024	Enoyl-CoA hydratase
ABC08_12760	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC08_12765	COG3842	ATPase activity
ABC08_12780	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_12800	COG0583	DNA-binding transcription factor activity
ABC08_12805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_12815	COG2974	May be involved in recombination
ABC08_12820	COG0540	Belongs to the ATCase OTCase family
ABC08_12890	COG0776	regulation of translation
ABC08_12895	COG0072	phenylalanine-tRNA ligase activity
ABC08_12895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC08_12900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABC08_12905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABC08_12910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABC08_12920	COG0756	dUTP diphosphatase activity
ABC08_12930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC08_12945	COG0500	methyltransferase
ABC08_12955	COG0586	Pfam SNARE associated Golgi protein
ABC08_12980	COG1609	Transcriptional regulator
ABC08_12985	COG4172	Belongs to the ABC transporter superfamily
ABC08_12995	COG0601	transmembrane transport
ABC08_13000	COG0747	negative chemotaxis
ABC08_13015	COG1280	lysine exporter protein (LysE YggA)
ABC08_13030	COG2814	Major facilitator Superfamily
ABC08_13060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABC08_13075	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABC08_13110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_13115	COG1116	anion transmembrane transporter activity
ABC08_13125	COG1228	amidohydrolase
ABC08_13140	COG0477	Major facilitator Superfamily
ABC08_13150	COG3550	peptidyl-serine autophosphorylation
ABC08_13160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC08_13160	COG0519	Catalyzes the synthesis of GMP from XMP
ABC08_13185	COG2197	response regulator
ABC08_13210	COG0420	3'-5' exonuclease activity
ABC08_13215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_13245	COG0395	ABC-type sugar transport system, permease component
ABC08_13255	COG3842	ATPase activity
ABC08_13285	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_13290	COG1053	succinate dehydrogenase
ABC08_13320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC08_13345	COG0602	queuosine metabolic process
ABC08_13350	COG0720	synthase
ABC08_13355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC08_13360	COG0235	Class ii aldolase
ABC08_13385	COG3210	domain, Protein
ABC08_13385	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC08_13385	COG3064	Membrane
ABC08_13390	COG0047	phosphoribosylformylglycinamidine synthase activity
ABC08_13390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABC08_13395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC08_13400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC08_13405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC08_13420	COG3539	Fimbrial protein
ABC08_13430	COG2050	protein possibly involved in aromatic compounds catabolism
ABC08_13435	COG1024	Enoyl-CoA hydratase
ABC08_13440	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_13455	COG2151	metal-sulfur cluster biosynthetic enzyme
ABC08_13460	COG3396	Phenylacetate-CoA oxygenase
ABC08_13465	COG3460	Phenylacetate-CoA oxygenase
ABC08_13470	COG3396	Phenylacetate-CoA oxygenase
ABC08_13475	COG3327	negative regulation of DNA-templated transcription, initiation
ABC08_13485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABC08_13490	COG0501	Belongs to the peptidase M48B family
ABC08_13495	COG1162	GTPase activity
ABC08_13505	COG0601	transmembrane transport
ABC08_13510	COG0747	negative chemotaxis
ABC08_13555	COG0668	transmembrane transport
ABC08_13560	COG0165	Argininosuccinate lyase
ABC08_13580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABC08_13585	COG0303	'Molybdopterin
ABC08_13590	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABC08_13605	COG0315	cyclic pyranopterin monophosphate synthase activity
ABC08_13615	COG0412	Dienelactone hydrolase
ABC08_13625	COG0678	peroxiredoxin activity
ABC08_13635	COG0697	spore germination
ABC08_13640	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABC08_13665	COG0789	Transcriptional regulator
ABC08_13685	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_13695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC08_13700	COG1845	cytochrome c oxidase, subunit III
ABC08_13705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC08_13715	COG0477	Major facilitator Superfamily
ABC08_13745	COG3468	outer membrane autotransporter barrel domain protein
ABC08_13755	COG1309	transcriptional regulator
ABC08_13760	COG2271	Major facilitator Superfamily
ABC08_13780	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_13795	COG0506	proline dehydrogenase activity
ABC08_13795	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABC08_13795	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABC08_13805	COG3008	intermembrane lipid transfer
ABC08_13805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABC08_13810	COG2995	paraquat-inducible protein a
ABC08_13815	COG0542	response to heat
ABC08_13820	COG4953	penicillin-binding protein 1C
ABC08_13830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABC08_13835	COG1278	Cold shock
ABC08_13845	COG0183	Belongs to the thiolase family
ABC08_13850	COG0038	chloride channel
ABC08_13855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC08_13860	COG1570	exodeoxyribonuclease VII activity
ABC08_13870	COG0811	peptide transport
ABC08_13875	COG0848	biopolymer transport protein
ABC08_13880	COG1663	tetraacyldisaccharide 4'-kinase activity
ABC08_13885	COG2835	tetraacyldisaccharide 4'-kinase activity
ABC08_13890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABC08_13895	COG0563	adenylate kinase activity
ABC08_13905	COG0728	peptidoglycan biosynthetic process
ABC08_13915	COG0268	Binds directly to 16S ribosomal RNA
ABC08_13945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC08_13970	COG0436	Aminotransferase
ABC08_13975	COG3737	Protein of unknown function (DUF498/DUF598)
ABC08_13980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABC08_13985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABC08_13990	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC08_14000	COG0305	Participates in initiation and elongation during chromosome replication
ABC08_14010	COG0359	binds to the 23S rRNA
ABC08_14015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABC08_14020	COG2965	DNA replication, synthesis of RNA primer
ABC08_14025	COG0360	Binds together with S18 to 16S ribosomal RNA
ABC08_14030	COG1469	GTP cyclohydrolase I activity
ABC08_14035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABC08_14040	COG0142	geranyltranstransferase activity
ABC08_14045	COG1722	exodeoxyribonuclease VII activity
ABC08_14055	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_14075	COG2239	Acts as a magnesium transporter
ABC08_14080	COG1607	acyl-coa hydrolase
ABC08_14085	COG2855	membrane
ABC08_14095	COG1473	amidohydrolase
ABC08_14100	COG0318	PFAM AMP-dependent synthetase and ligase
ABC08_14120	COG1501	Belongs to the glycosyl hydrolase 31 family
ABC08_14125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC08_14130	COG2011	ABC-type metal ion transport system permease component
ABC08_14150	COG1454	alcohol dehydrogenase
ABC08_14175	COG2186	Transcriptional regulator
ABC08_14180	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_14200	COG1175	transmembrane transport
ABC08_14205	COG0395	ABC-type sugar transport system, permease component
ABC08_14210	COG3842	ATPase activity
ABC08_14225	COG1653	transport
ABC08_14245	COG2818	Glycosylase
ABC08_14250	COG2982	Protein involved in outer membrane biogenesis
ABC08_14260	COG1309	transcriptional regulator
ABC08_14265	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_14305	COG0583	DNA-binding transcription factor activity
ABC08_14310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABC08_14315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC08_14330	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_14335	COG0477	Major facilitator Superfamily
ABC08_14345	COG0583	DNA-binding transcription factor activity
ABC08_14350	COG1448	Aminotransferase
ABC08_14355	COG1418	mRNA catabolic process
ABC08_14380	COG1063	alcohol dehydrogenase
ABC08_14400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_14410	COG0318	PFAM AMP-dependent synthetase and ligase
ABC08_14420	COG1522	sequence-specific DNA binding
ABC08_14425	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_14430	COG0307	riboflavin synthase, alpha
ABC08_14435	COG0154	amidase activity
ABC08_14455	COG2807	transmembrane transport
ABC08_14460	COG0590	tRNA wobble adenosine to inosine editing
ABC08_14470	COG0583	DNA-binding transcription factor activity
ABC08_14490	COG0410	ABC transporter
ABC08_14505	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_14510	COG0251	oxidation-reduction process
ABC08_14525	COG1414	Transcriptional regulator
ABC08_14530	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_14545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_14560	COG1024	Enoyl-CoA hydratase
ABC08_14565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_14570	COG0154	amidase activity
ABC08_14610	COG3909	cytochrome
ABC08_14615	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABC08_14620	COG0625	glutathione transferase activity
ABC08_14625	COG0730	response to heat
ABC08_14630	COG0482	sulfurtransferase activity
ABC08_14635	COG0583	DNA-binding transcription factor activity
ABC08_14650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ABC08_14655	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ABC08_14670	COG2819	hydrolase of the alpha beta superfamily
ABC08_14675	COG0247	lactate metabolic process
ABC08_14680	COG0277	FAD linked oxidase domain protein
ABC08_14685	COG0277	FAD linked oxidase domain protein
ABC08_14690	COG0277	FAD linked oxidase domain protein
ABC08_14695	COG3210	domain, Protein
ABC08_14695	COG3064	Membrane
ABC08_14695	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC08_14695	COG3210	domain, Protein
ABC08_14695	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC08_14695	COG3064	Membrane
ABC08_14700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABC08_14705	COG0312	modulator of DNA gyrase
ABC08_14710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABC08_14785	COG3220	belongs to the UPF0276 family
ABC08_14805	COG0640	Transcriptional regulator
ABC08_14810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC08_14815	COG1845	cytochrome c oxidase, subunit III
ABC08_14820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC08_14830	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ABC08_14870	COG0583	DNA-binding transcription factor activity
ABC08_14900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC08_14900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC08_14915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABC08_14920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABC08_14930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABC08_14945	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABC08_14950	COG0316	Belongs to the HesB IscA family
ABC08_14960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABC08_14965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABC08_14970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABC08_14975	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC08_14980	COG0312	modulator of DNA gyrase
ABC08_14985	COG3028	Belongs to the UPF0307 family
ABC08_15000	COG1116	anion transmembrane transporter activity
ABC08_15005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_15010	COG1335	isochorismatase
ABC08_15015	COG0346	lactoylglutathione lyase activity
ABC08_15020	COG0513	Belongs to the DEAD box helicase family
ABC08_15025	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC08_15030	COG1802	Transcriptional regulator
ABC08_15040	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC08_15040	COG1042	CoA-binding domain protein
ABC08_15040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABC08_15045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC08_15060	COG1522	sequence-specific DNA binding
ABC08_15095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABC08_15100	COG1696	Membrane protein involved in D-alanine export
ABC08_15140	COG0439	Biotin carboxylase
ABC08_15145	COG0511	ligase activity, forming carbon-carbon bonds
ABC08_15150	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABC08_15155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC08_15160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC08_15165	COG3150	esterase
ABC08_15170	COG0557	exoribonuclease II activity
ABC08_15180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABC08_15200	COG1522	sequence-specific DNA binding
ABC08_15205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_15210	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_15230	COG0653	protein targeting
ABC08_15235	COG0739	heme binding
ABC08_15245	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABC08_15250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABC08_15260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABC08_15265	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABC08_15270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC08_15275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABC08_15285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABC08_15290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC08_15295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC08_15305	COG3116	cell division
ABC08_15310	COG0275	rRNA processing
ABC08_15315	COG2001	Belongs to the MraZ family
ABC08_15325	COG0418	dihydroorotase activity
ABC08_15330	COG1473	amidohydrolase
ABC08_15370	COG1522	sequence-specific DNA binding
ABC08_15380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC08_15385	COG4654	Cytochrome c, class I
ABC08_15390	COG0129	dihydroxy-acid dehydratase activity
ABC08_15395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABC08_15445	COG2084	Dehydrogenase
ABC08_15465	COG2096	Adenosyltransferase
ABC08_15475	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABC08_15480	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABC08_15485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABC08_15490	COG0523	cobalamin synthesis protein
ABC08_15495	COG0735	belongs to the Fur family
ABC08_15505	COG1121	(ABC) transporter
ABC08_15515	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABC08_15525	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABC08_15535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABC08_15545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABC08_15550	COG1560	Kdo2-lipid A biosynthetic process
ABC08_15560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABC08_15575	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABC08_15580	COG1950	PFAM Membrane protein of
ABC08_15595	COG0583	DNA-binding transcription factor activity
ABC08_15605	COG0477	Major facilitator Superfamily
ABC08_15620	COG0617	tRNA 3'-terminal CCA addition
ABC08_15630	COG0513	Belongs to the DEAD box helicase family
ABC08_15635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABC08_15645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC08_15650	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ABC08_15725	COG0405	Gamma-glutamyltransferase
ABC08_15735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_15760	COG1309	transcriptional regulator
ABC08_15775	COG0745	RESPONSE REGULATOR receiver
ABC08_15820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABC08_15840	COG0582	viral genome integration into host DNA
ABC08_15845	COG0012	GTP binding
ABC08_15855	COG0193	aminoacyl-tRNA hydrolase activity
ABC08_15860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABC08_15865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABC08_15875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABC08_15880	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABC08_15890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABC08_15915	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ABC08_15925	COG1368	sulfuric ester hydrolase activity
ABC08_15930	COG0642	Histidine kinase
ABC08_15935	COG0745	RESPONSE REGULATOR receiver
ABC08_15940	COG0277	FAD linked oxidase domain protein
ABC08_15955	COG0166	Belongs to the GPI family
ABC08_15960	COG0438	transferase activity, transferring glycosyl groups
ABC08_15965	COG0438	transferase activity, transferring glycosyl groups
ABC08_15980	COG0438	transferase activity, transferring glycosyl groups
ABC08_15995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC08_16000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC08_16005	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ABC08_16015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABC08_16025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC08_16040	COG0747	negative chemotaxis
ABC08_16045	COG0601	transmembrane transport
ABC08_16050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_16070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABC08_16075	COG0830	nickel cation binding
ABC08_16085	COG0804	urea catabolic process
ABC08_16090	COG0832	Belongs to the urease beta subunit family
ABC08_16100	COG0831	urea catabolic process
ABC08_16105	COG0829	nickel cation binding
ABC08_16130	COG2188	Transcriptional regulator
ABC08_16155	COG2719	SpoVR family
ABC08_16160	COG2718	Belongs to the UPF0229 family
ABC08_16180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_16195	COG1960	acyl-CoA dehydrogenase activity
ABC08_16215	COG0411	ABC transporter
ABC08_16305	COG0328	RNA-DNA hybrid ribonuclease activity
ABC08_16310	COG2226	methyltransferase
ABC08_16320	COG0741	lytic transglycosylase activity
ABC08_16320	COG1388	LysM domain
ABC08_16340	COG2979	Protein of unknown function (DUF533)
ABC08_16360	COG0745	RESPONSE REGULATOR receiver
ABC08_16375	COG1271	oxidase subunit
ABC08_16380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC08_16385	COG0850	regulation of cytokinetic process
ABC08_16390	COG2894	cell division
ABC08_16395	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ABC08_16425	COG0601	transmembrane transport
ABC08_16435	COG1215	transferase activity, transferring glycosyl groups
ABC08_16450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABC08_16460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC08_16480	COG0318	PFAM AMP-dependent synthetase and ligase
ABC08_16485	COG2188	Transcriptional regulator
ABC08_16490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABC08_16495	COG2814	Major facilitator Superfamily
ABC08_16505	COG0259	pyridoxamine-phosphate oxidase activity
ABC08_16510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABC08_16525	COG0583	DNA-binding transcription factor activity
ABC08_16555	COG0134	indole-3-glycerol-phosphate synthase activity
ABC08_16560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABC08_16565	COG0512	Glutamine amidotransferase of anthranilate synthase
ABC08_16575	COG0546	phosphoglycolate phosphatase activity
ABC08_16585	COG2967	ApaG domain
ABC08_16590	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABC08_16595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC08_16600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABC08_16605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC08_16615	COG0037	tRNA processing
ABC08_16625	COG3634	alkyl hydroperoxide reductase activity
ABC08_16630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC08_16635	COG1024	Enoyl-CoA hydratase
ABC08_16660	COG0356	it plays a direct role in the translocation of protons across the membrane
ABC08_16670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABC08_16675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABC08_16680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABC08_16685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABC08_16690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABC08_16695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABC08_16705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABC08_16710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABC08_16715	COG0210	DNA helicase
ABC08_16725	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABC08_16735	COG4172	Belongs to the ABC transporter superfamily
ABC08_16740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_16745	COG0601	transmembrane transport
ABC08_16765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABC08_16770	COG1024	Enoyl-CoA hydratase
ABC08_16775	COG1024	Enoyl-CoA hydratase
ABC08_16830	COG2132	Multicopper oxidase
ABC08_16840	COG1024	Enoyl-CoA hydratase
ABC08_16840	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC08_16855	COG1414	Transcriptional regulator
ABC08_16865	COG0154	amidase activity
ABC08_16895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC08_16900	COG3568	Endonuclease Exonuclease Phosphatase
ABC08_16905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABC08_16935	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABC08_16945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABC08_16960	COG1137	ATPase activity
ABC08_16965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABC08_16975	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ABC08_16980	COG2010	Cytochrome c
ABC08_16980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABC08_16995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABC08_17035	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_17045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABC08_17050	COG2890	protein-(glutamine-N5) methyltransferase activity
ABC08_17055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABC08_17060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABC08_17105	COG1960	acyl-CoA dehydrogenase activity
ABC08_17115	COG0183	Belongs to the thiolase family
ABC08_17120	COG1522	sequence-specific DNA binding
ABC08_17125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABC08_17145	COG1024	Enoyl-CoA hydratase
ABC08_17160	COG0604	alcohol dehydrogenase
ABC08_17180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC08_17190	COG1960	acyl-CoA dehydrogenase activity
ABC08_17195	COG1960	acyl-CoA dehydrogenase activity
ABC08_17200	COG0277	FAD linked oxidase domain protein
ABC08_17210	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_17230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC08_17240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_17245	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_17250	COG1960	acyl-CoA dehydrogenase activity
ABC08_17270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC08_17275	COG1024	Enoyl-CoA hydratase
ABC08_17280	COG1960	acyl-CoA dehydrogenase activity
ABC08_17300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABC08_17305	COG0022	dehydrogenase e1 component
ABC08_17310	COG1024	Enoyl-CoA hydratase
ABC08_17315	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC08_17335	COG0683	leucine binding
ABC08_17340	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_17345	COG0411	ABC transporter
ABC08_17350	COG0410	ABC transporter
ABC08_17355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC08_17370	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_17395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABC08_17400	COG0793	Belongs to the peptidase S41A family
ABC08_17405	COG4942	peptidase
ABC08_17410	COG0588	phosphoglycerate mutase activity
ABC08_17420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABC08_17425	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ABC08_17430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABC08_17435	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_17450	COG2226	methyltransferase
ABC08_17455	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ABC08_17470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_17475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC08_17500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC08_17525	COG1335	isochorismatase
ABC08_17530	COG2309	aminopeptidase activity
ABC08_17540	COG3473	Maleate cis-trans isomerase
ABC08_17550	COG2068	MobA-Related Protein
ABC08_17570	COG0569	domain protein
ABC08_17575	COG2204	response regulator
ABC08_17580	COG5000	phosphorelay sensor kinase activity
ABC08_17590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC08_17590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABC08_17600	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ABC08_17625	COG0583	DNA-binding transcription factor activity
ABC08_17645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC08_17650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_17665	COG0758	DNA mediated transformation
ABC08_17670	COG1522	sequence-specific DNA binding
ABC08_17680	COG0242	peptide deformylase activity
ABC08_17690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABC08_17700	COG0546	phosphoglycolate phosphatase activity
ABC08_17725	COG1942	4-Oxalocrotonate Tautomerase
ABC08_17730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC08_17750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC08_17770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC08_17775	COG1024	Enoyl-CoA hydratase
ABC08_17780	COG1414	Transcriptional regulator
ABC08_17785	COG0318	PFAM AMP-dependent synthetase and ligase
ABC08_17790	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_17840	COG0330	HflC and HflK could
ABC08_17850	COG0251	oxidation-reduction process
ABC08_17895	COG3723	Recombinational DNA repair protein, rece pathway
ABC08_17930	COG0582	viral genome integration into host DNA
ABC08_17965	COG0706	membrane insertase activity
ABC08_17970	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABC08_17975	COG0594	ribonuclease P activity
ABC08_17980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABC08_18000	COG1414	Transcriptional regulator
ABC08_18005	COG0154	amidase activity
ABC08_18020	COG1304	FMN binding
ABC08_18045	COG1960	acyl-CoA dehydrogenase activity
ABC08_18075	COG0183	Belongs to the thiolase family
ABC08_18080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC08_18095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC08_18100	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_18120	COG1629	transport
ABC08_18125	COG2922	Belongs to the Smg family
ABC08_18150	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC08_18155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_18160	COG1028	Short-chain dehydrogenase reductase Sdr
ABC08_18165	COG1012	belongs to the aldehyde dehydrogenase family
ABC08_18175	COG0028	Belongs to the TPP enzyme family
ABC08_18180	COG1522	sequence-specific DNA binding
ABC08_18185	COG3781	membrane
ABC08_18195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABC08_18215	COG4206	TonB-dependent receptor
ABC08_18220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC08_18225	COG2022	thiamine diphosphate biosynthetic process
ABC08_18230	COG0351	phosphomethylpyrimidine kinase
ABC08_18235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABC08_18250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABC08_18260	COG0628	permease
ABC08_18270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABC08_18280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABC08_18285	COG0049	tRNA binding
ABC08_18290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC08_18295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC08_18300	COG0051	transcription antitermination factor activity, RNA binding
ABC08_18305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABC08_18310	COG0088	Forms part of the polypeptide exit tunnel
ABC08_18315	COG0089	rRNA binding
ABC08_18320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABC08_18325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABC08_18330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABC08_18335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABC08_18340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABC08_18345	COG0255	Belongs to the universal ribosomal protein uL29 family
ABC08_18350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABC08_18370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABC08_18375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABC08_18380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABC08_18385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABC08_18390	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABC08_18395	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABC08_18400	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABC08_18405	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABC08_18410	COG1841	ribosomal large subunit assembly
ABC08_18415	COG0200	Binds to the 23S rRNA
ABC08_18420	COG0201	protein transport
ABC08_18425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC08_18430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABC08_18435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABC08_18440	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABC08_18445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABC08_18450	COG0202	RNA polymerase activity
ABC08_18465	COG1324	tolerance protein
ABC08_18470	COG4232	protein-disulfide reductase activity
ABC08_18485	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABC08_18495	COG1333	cytochrome c biogenesis protein
ABC08_18500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC08_18510	COG1965	Belongs to the frataxin family
ABC08_18525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABC08_18530	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ABC08_18545	COG2814	Major facilitator Superfamily
ABC08_18550	COG0629	single-stranded DNA binding
ABC08_18600	COG0438	transferase activity, transferring glycosyl groups
ABC08_18620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_18645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABC08_18670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC08_18675	COG1956	GAF domain-containing protein
ABC08_18680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC08_18690	COG1652	LysM domain
ABC08_18705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABC08_18720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC08_18745	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_18760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_18775	COG1024	Enoyl-CoA hydratase
ABC08_18790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_18795	COG1309	transcriptional regulator
ABC08_18800	COG2816	NAD+ diphosphatase activity
ABC08_18805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC08_18850	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC08_18895	COG2814	Major facilitator Superfamily
ABC08_18900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABC08_18920	COG1999	signal sequence binding
ABC08_18925	COG0109	protoheme IX farnesyltransferase activity
ABC08_18965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC08_18985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC08_18990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC08_19000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ABC08_19005	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ABC08_19015	COG0069	glutamate synthase activity
ABC08_19015	COG0070	glutamate synthase
ABC08_19015	COG0067	glutamate synthase
ABC08_19025	COG3047	cAMP biosynthetic process
ABC08_19035	COG1127	ABC transporter
ABC08_19040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABC08_19045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABC08_19050	COG2853	Lipoprotein
ABC08_19065	COG0842	Transport permease protein
ABC08_19075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABC08_19080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABC08_19085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABC08_19090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC08_19095	COG0131	Imidazoleglycerol-phosphate dehydratase
ABC08_19100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABC08_19105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABC08_19110	COG0107	imidazoleglycerol-phosphate synthase activity
ABC08_19115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABC08_19125	COG0537	adenosine 5'-monophosphoramidase activity
ABC08_19130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC08_19135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC08_19150	COG3181	Tripartite tricarboxylate transporter family receptor
ABC08_19190	COG3451	type IV secretory pathway VirB4
ABC08_19210	COG3504	Conjugal transfer protein
ABC08_19215	COG2948	multi-organism process
ABC08_19230	COG0697	spore germination
ABC08_19250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC08_19255	COG0747	negative chemotaxis
ABC08_19265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC08_19270	COG0444	Belongs to the ABC transporter superfamily
ABC08_19280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABC08_19290	COG0494	nUDIX hydrolase
ABC08_19310	COG1538	Outer membrane efflux protein
ABC08_19330	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ABC08_19335	COG0237	dephospho-CoA kinase activity
ABC08_19340	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABC08_19355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABC08_19360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABC08_19370	COG0477	Major facilitator Superfamily
ABC08_19375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABC08_19390	COG1126	abc transporter atp-binding protein
ABC08_19395	COG0765	amino acid transport
ABC08_19400	COG4597	amino acid ABC transporter
ABC08_19405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC08_19410	COG2884	Cell division ATP-binding protein ftsE
ABC08_19415	COG2177	Part of the ABC transporter FtsEX involved in
ABC08_19420	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABC08_19430	COG1194	a g-specific adenine glycosylase
ABC08_19440	COG2226	methyltransferase
ABC08_19450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_19455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_19470	COG1024	Enoyl-CoA hydratase
ABC08_19490	COG1024	Enoyl-CoA hydratase
ABC08_19495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC08_19510	COG0753	catalase activity
ABC08_19515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC08_19520	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC08_19530	COG2175	clavaminate synthase activity
ABC08_19535	COG1473	amidohydrolase
ABC08_19540	COG4608	Belongs to the ABC transporter superfamily
ABC08_19545	COG0444	Belongs to the ABC transporter superfamily
ABC08_19555	COG0601	transmembrane transport
ABC08_19560	COG0747	negative chemotaxis
ABC08_19565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC08_19580	COG5002	protein histidine kinase activity
ABC08_19580	COG3850	Histidine kinase
ABC08_19600	COG0436	Aminotransferase