locus-tag	class	description
C5F13_00005	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C5F13_00015	ENOG4107QJE	Chromosome Partitioning Protein
C5F13_00025	ENOG4105FA0	parb-like partition protein
C5F13_00050	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C5F13_00060	ENOG410683Z	Preprotein translocase SecE subunit
C5F13_00070	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C5F13_00075	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C5F13_00080	ENOG4108VZM	50s ribosomal protein L10
C5F13_00085	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C5F13_00090	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C5F13_00095	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C5F13_00125	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C5F13_00160	ENOG4105E39	Enoyl-CoA hydratase
C5F13_00180	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
C5F13_00185	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C5F13_00190	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
C5F13_00195	ENOG4105E9Q	Acyl-transferase
C5F13_00210	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C5F13_00250	ENOG4105DWV	Homoserine O-trans-acetylase
C5F13_00255	ENOG4105DWV	Homoserine O-trans-acetylase
C5F13_00270	ENOG4105EYM	Major Facilitator superfamily
C5F13_00285	ENOG4105CDA	abc transporter atp-binding protein
C5F13_00290	ENOG4105DRP	amino acid AbC transporter
C5F13_00295	ENOG4105EAD	ABC transporter
C5F13_00300	ENOG4107RP9	extracellular solute-binding protein, family 3
C5F13_00355	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_00365	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C5F13_00395	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C5F13_00400	ENOG4108TGY	Glutathione S-transferase
C5F13_00415	ENOG4105CRE	cytochrome C
C5F13_00420	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5F13_00450	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
C5F13_00455	ENOG4105D3Q	Sugar transferase
C5F13_00460	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C5F13_00470	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C5F13_00475	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C5F13_00480	ENOG4105J5G	Transferase hexapeptide repeat containing protein
C5F13_00490	ENOG4105D16	lipopolysaccharide heptosyltransferase i
C5F13_00495	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
C5F13_00505	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C5F13_00520	ENOG4105DHJ	ABC, transporter
C5F13_00540	ENOG4105DZ1	carboxypeptidase
C5F13_00545	ENOG4105F0I	Aminotransferase
C5F13_00550	ENOG4108Z43	UPF0250 protein
C5F13_00555	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C5F13_00560	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C5F13_00565	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
C5F13_00595	ENOG4108Z33	Thiol disulfide Interchange Protein
C5F13_00605	ENOG4105C75	arginyL-tRNA synthetase
C5F13_00625	ENOG4105DRS	transport system, permease
C5F13_00630	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
C5F13_00635	ENOG4105BZ7	extracellular solute-binding protein family 1
C5F13_00640	ENOG4108IJ9	(ABC) transporter
C5F13_00645	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
C5F13_00655	ENOG4108IJ6	ABC transporter
C5F13_00660	ENOG4105E0C	molybdate abc transporter
C5F13_00675	ENOG4105ETE	Transcriptional regulator (LacI family
C5F13_00685	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_00690	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C5F13_00700	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C5F13_00730	ENOG4105C7B	Threonine dehydratase
C5F13_00745	ENOG4105DRR	Transcriptional regulator, GntR family
C5F13_00795	ENOG4105P4J	Allophanate hydrolase, subunit 1
C5F13_00805	ENOG4108M0I	Transcriptional regulator
C5F13_00810	ENOG4108JQ1	Dehydrogenase
C5F13_00820	ENOG4105GR3	Histidine kinase
C5F13_00830	ENOG4105BZU	Histidine kinase
C5F13_00835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C5F13_00840	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C5F13_00855	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C5F13_00875	ENOG4105HA9	of methanol dehydrogenase type
C5F13_00885	ENOG4105C1J	atp-dependent rna helicase
C5F13_00890	ENOG410829K	Lysine exporter protein (Lyse ygga)
C5F13_00895	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C5F13_00905	ENOG4108UQY	Iron-storage protein
C5F13_00930	ENOG4105C72	UPF0176 protein
C5F13_00935	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C5F13_00960	ENOG4105DHP	deoxycytidine triphosphate deaminase
C5F13_00985	ENOG4105CXN	decarboxylase
C5F13_00990	ENOG4105CBX	hi0933 family
C5F13_01010	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C5F13_01015	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C5F13_01020	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5F13_01060	ENOG4105F2Z	3-oxoadipate enol-lactonase
C5F13_01075	ENOG4107QNJ	CoA-transferase subunit B
C5F13_01085	ENOG4107HP6	Transcriptional regulator
C5F13_01090	ENOG4105CHR	reductase
C5F13_01095	ENOG4105CRW	Short chain fatty acid transporter
C5F13_01100	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C5F13_01110	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C5F13_01115	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C5F13_01125	ENOG4105F9V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
C5F13_01150	ENOG4105C26	Dehydrogenase
C5F13_01155	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C5F13_01160	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C5F13_01165	ENOG4105S7Q	restriction endonuclease
C5F13_01195	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C5F13_01205	ENOG4105FDP	GntR family transcriptional regulator
C5F13_01210	ENOG4105CH5	extracellular solute-binding protein, family 7
C5F13_01215	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_01230	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C5F13_01235	ENOG4105DJ0	Poly(A) Polymerase
C5F13_01250	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C5F13_01255	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C5F13_01260	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C5F13_01265	ENOG4105DQR	SNARE associated Golgi
C5F13_01270	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C5F13_01275	ENOG4105K8N	protein family UPF0079, ATPase
C5F13_01280	ENOG4105C9Q	fumarate hydratase class II
C5F13_01300	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C5F13_01305	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_01335	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C5F13_01340	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C5F13_01350	ENOG4108JJ9	ABC, transporter
C5F13_01355	ENOG4108JJ8	(ABC) transporter
C5F13_01360	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C5F13_01410	ENOG4105KB2	stringent starvation protein b
C5F13_01415	ENOG4107MKT	Stringent starvation protein a
C5F13_01420	ENOG4105EIX	cytochrome c1
C5F13_01425	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C5F13_01430	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C5F13_01435	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C5F13_01440	ENOG4107QNR	UPF0135 protein
C5F13_01460	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
C5F13_01465	ENOG4105DEF	Extracellular solute-binding protein, family 5
C5F13_01470	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
C5F13_01480	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C5F13_01490	ENOG4105C01	Dihydroxy-acid dehydratase
C5F13_01495	ENOG4105F27	Major Facilitator
C5F13_01500	ENOG4105HEI	LysR family (Transcriptional regulator
C5F13_01510	ENOG4105GP2	5'(3')-deoxyribonucleotidase
C5F13_01550	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_01555	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C5F13_01560	ENOG4105C0Z	ABC transporter
C5F13_01565	ENOG4108IV0	ABC, transporter
C5F13_01580	ENOG4108UKI	Enoyl-CoA hydratase
C5F13_01585	ENOG4105C1G	acyl-Coa dehydrogenase
C5F13_01610	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C5F13_01625	ENOG4105VCQ	rubredoxin
C5F13_01630	ENOG4108UJU	UPF0301 protein
C5F13_01635	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C5F13_01640	ENOG4105CXT	aspartate transcarbamylase
C5F13_01645	ENOG4105CD3	dihydroorotase
C5F13_01650	ENOG4108Z20	Acyl-transferase
C5F13_01655	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
C5F13_01665	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
C5F13_01700	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
C5F13_01720	ENOG4108NST	exported protein
C5F13_01730	ENOG4105BZU	Histidine kinase
C5F13_01735	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C5F13_01740	ENOG4105CF1	Alkylated DNA repair protein
C5F13_01750	ENOG4105EWC	Purine nucleoside phosphorylase
C5F13_01755	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
C5F13_01760	ENOG4105EHG	Permease protein
C5F13_01765	ENOG4107R4I	Periplasmic binding protein
C5F13_01770	ENOG4106QJH	hemin transport protein
C5F13_01780	ENOG4108S3W	Anti-feci sigma factor, fecr
C5F13_01785	ENOG4108SF5	RNA Polymerase
C5F13_01810	ENOG4105CIF	Ornithine Cyclodeaminase
C5F13_01820	ENOG4105DRR	Transcriptional regulator, GntR family
C5F13_01840	ENOG4105C26	Dehydrogenase
C5F13_01875	ENOG4105EN6	Membrane
C5F13_01880	ENOG4105D82	Glutamate dehydrogenase
C5F13_01885	ENOG4105CGK	Exodeoxyribonuclease III
C5F13_01890	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C5F13_01895	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C5F13_01900	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_01905	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C5F13_01910	ENOG4105DFF	Rod shape-determining protein mreb
C5F13_01915	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C5F13_01925	ENOG4105CJN	penicillin-binding protein
C5F13_01930	ENOG4105CNI	cell division protein FtsW
C5F13_01935	ENOG4105DG4	malate L-lactate dehydrogenase
C5F13_01940	ENOG4107QPK	)-transporter
C5F13_01945	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
C5F13_01955	ENOG4105CAS	nag kinase
C5F13_01960	ENOG4105D01	(LipO)protein
C5F13_01970	ENOG4105W4M	Transport-associated protein
C5F13_01975	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
C5F13_01990	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C5F13_02020	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_02040	ENOG4105C3M	thioredoxin reductase
C5F13_02055	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C5F13_02060	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_02065	ENOG4105C7K	acetolactate synthase
C5F13_02080	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C5F13_02105	ENOG4105T38	integral membrane protein
C5F13_02135	ENOG4107SH3	glycosyl transferase, family 39
C5F13_02155	ENOG4105D6U	Sodium Glutamate Symporter
C5F13_02165	ENOG4105CRW	Short chain fatty acid transporter
C5F13_02180	ENOG4107RZZ	dna polymerase iii epsilon subunit
C5F13_02195	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C5F13_02210	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C5F13_02220	ENOG4108302	MgtC SapB transporter
C5F13_02225	ENOG4105EE5	Membrane protein terC
C5F13_02230	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_02235	ENOG4105E39	Enoyl-CoA hydratase
C5F13_02245	ENOG4106NZI	LysR family Transcriptional regulator
C5F13_02250	ENOG4105CC9	acyl-Coa dehydrogenase
C5F13_02260	ENOG4105CHU	acetyl-coa acetyltransferase
C5F13_02280	ENOG4105DND	Transcriptional regulator
C5F13_02285	ENOG4105VEQ	Cold shock protein
C5F13_02295	ENOG4108WYP	Transcriptional regulator
C5F13_02300	ENOG4105C26	Dehydrogenase
C5F13_02305	ENOG4105CRW	Short chain fatty acid transporter
C5F13_02310	ENOG4108DEF	Globin
C5F13_02315	ENOG4108UQ8	endoribonuclease L-psp
C5F13_02335	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
C5F13_02345	ENOG4105DND	Transcriptional regulator
C5F13_02350	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_02360	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
C5F13_02365	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
C5F13_02370	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C5F13_02375	ENOG4105EI2	Pseudouridine synthase
C5F13_02380	ENOG4105C03	ribonuclease
C5F13_02405	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C5F13_02410	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C5F13_02415	ENOG4105CWC	Acetylornithine deacetylase
C5F13_02420	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C5F13_02425	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
C5F13_02435	ENOG4105M4H	endoribonuclease L-psp
C5F13_02440	ENOG4107RH7	Nicotinate phosphoribosyltransferase
C5F13_02445	ENOG4108Z4U	Ferredoxin
C5F13_02450	ENOG4105DP0	ferredoxin-NADP reductase
C5F13_02460	ENOG4108R3D	Electron transport complex
C5F13_02465	ENOG4105CSM	endonuclease III
C5F13_02470	ENOG4105C0Z	ABC transporter
C5F13_02475	ENOG4108IV0	ABC, transporter
C5F13_02485	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_02500	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C5F13_02505	ENOG4105C0Z	ABC transporter
C5F13_02520	ENOG4107ZYJ	bioY protein
C5F13_02525	ENOG4107QCX	Transporter
C5F13_02530	ENOG4108JJB	ABC transporter
C5F13_02535	ENOG4105E0X	reductase
C5F13_02555	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C5F13_02565	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C5F13_02570	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
C5F13_02575	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
C5F13_02580	ENOG41072GX	Peptidase M22 Glycoprotease
C5F13_02585	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C5F13_02595	ENOG4105E0F	Histidine kinase
C5F13_02600	ENOG4105D3R	alkyl hydroperoxide reductase
C5F13_02605	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
C5F13_02625	ENOG4107YCY	Transcriptional regulator
C5F13_02645	ENOG4105C5I	Dehydrogenase
C5F13_02650	ENOG4105CHR	reductase
C5F13_02655	ENOG4105CBN	LysR family transcriptional regulator
C5F13_02665	ENOG4105C8Y	Acetylornithine aminotransferase
C5F13_02670	ENOG4105DBV	ornithine carbamoyltransferase
C5F13_02675	ENOG4105CDH	Citrulline--aspartate ligase
C5F13_02680	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C5F13_02685	ENOG4105DHQ	Histidine kinase
C5F13_02690	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C5F13_02715	ENOG4105K70	DNA-binding protein
C5F13_02720	ENOG4107E2E	PKHD-type hydroxylase
C5F13_02725	ENOG4105C28	cystathionine
C5F13_02730	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C5F13_02735	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C5F13_02755	ENOG41082BV	acetyltransferase
C5F13_02760	ENOG4105RK9	auxin efflux carrier
C5F13_02765	ENOG41066VF	YeeE YedE family protein
C5F13_02770	ENOG4105CBC	glutamate synthase
C5F13_02780	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C5F13_02790	ENOG41067HS	methyltransferase
C5F13_02825	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C5F13_02830	ENOG4105BZU	Histidine kinase
C5F13_02850	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
C5F13_02855	ENOG4105DUM	transcriptional regulator, lysR family
C5F13_02865	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
C5F13_02885	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C5F13_02890	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C5F13_02895	ENOG4108P8G	outer membrane autotransporter barrel
C5F13_02900	ENOG4107S2Z	UPF0761 membrane protein
C5F13_02905	ENOG41080IJ	Diacylglycerol kinase
C5F13_02910	ENOG4105CEP	NADH dehydrogenase
C5F13_02915	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C5F13_02920	ENOG4108I62	cina-like protein
C5F13_02925	ENOG4108ZAI	phosphatidylglycerophosphatase a
C5F13_02930	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C5F13_02935	ENOG4107YIM	Involved in the transcription termination process (By similarity)
C5F13_02940	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C5F13_02945	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C5F13_03005	ENOG4106H78	methyltransferase
C5F13_03010	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C5F13_03015	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C5F13_03020	ENOG4105DKK	Benzoate
C5F13_03035	ENOG41082BM	Transcriptional regulator, arsr family
C5F13_03065	ENOG4108JQ6	ABC transporter
C5F13_03085	ENOG4105C6K	Malic enzyme
C5F13_03145	ENOG4105CC0	LysR family Transcriptional regulator
C5F13_03160	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
C5F13_03165	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C5F13_03185	ENOG41069M3	Transcriptional regulator
C5F13_03190	ENOG4107TH8	cina domain protein
C5F13_03210	ENOG4105C1J	atp-dependent rna helicase
C5F13_03225	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C5F13_03240	ENOG4105DNZ	Alpha Beta Hydrolase
C5F13_03245	ENOG4105ERG	peptidase m48, ste24p
C5F13_03260	ENOG4108Z9W	Outer membrane porin
C5F13_03285	ENOG4107RAQ	aminopeptidase
C5F13_03295	ENOG4105D0A	hydroxylase
C5F13_03300	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C5F13_03315	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C5F13_03320	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C5F13_03335	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C5F13_03340	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C5F13_03360	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_03370	ENOG4108HWV	)-transporter
C5F13_03375	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_03380	ENOG4105C0Z	ABC transporter
C5F13_03385	ENOG4108IV0	ABC, transporter
C5F13_03400	ENOG4105D01	(LipO)protein
C5F13_03610	ENOG4108RAV	Conserved protein
C5F13_03625	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C5F13_03630	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C5F13_03635	ENOG4107YD3	Thioesterase
C5F13_03640	ENOG4105E02	MotA TolQ exbB proton channel
C5F13_03645	ENOG4105M8F	Biopolymer transport protein exbD tolR
C5F13_03655	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
C5F13_03660	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C5F13_03670	ENOG4105EHG	Permease protein
C5F13_03715	ENOG4105CA9	Pyruvate kinase
C5F13_03720	ENOG4105BZW	Glycerate kinase
C5F13_03725	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C5F13_03730	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C5F13_03735	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
C5F13_03740	ENOG4105EHM	Aminoglycoside phosphotransferase
C5F13_03745	ENOG4108S0S	Nucleotidyl transferase
C5F13_03755	ENOG4105KZX	Pterin carbinolamine dehydratase
C5F13_03780	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C5F13_03785	ENOG4105EUF	amidase EC 3.5.1.4
C5F13_03825	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
C5F13_03840	ENOG4108YYC	ycei family
C5F13_03845	ENOG4105E0K	tonB-dependent siderophore receptor
C5F13_03850	ENOG4108S3W	Anti-feci sigma factor, fecr
C5F13_03890	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C5F13_03895	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C5F13_03900	ENOG4105K46	50S ribosomal protein l27
C5F13_03905	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C5F13_03915	ENOG4105EAH	synthase
C5F13_03925	ENOG4105RQF	LysR family Transcriptional regulator
C5F13_03935	ENOG4107TYC	hydantoinase B oxoprolinase
C5F13_03940	ENOG4105DDR	sarcosine oxidase (Beta subunit)
C5F13_03945	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C5F13_03955	ENOG41090Q8	at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP
C5F13_03970	ENOG4108JJA	ABC, transporter
C5F13_03990	ENOG4107RP9	extracellular solute-binding protein, family 3
C5F13_04000	ENOG4105DRP	amino acid AbC transporter
C5F13_04005	ENOG4105CDA	abc transporter atp-binding protein
C5F13_04025	ENOG4105CHR	reductase
C5F13_04035	ENOG4108WYP	Transcriptional regulator
C5F13_04045	ENOG4105DRR	Transcriptional regulator, GntR family
C5F13_04050	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C5F13_04055	ENOG4105CEY	Amp-dependent synthetase and ligase
C5F13_04065	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C5F13_04075	ENOG4107UWC	ABC, transporter
C5F13_04085	ENOG4105C7K	acetolactate synthase
C5F13_04105	ENOG4105CD8	aminopeptidase N
C5F13_04110	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C5F13_04130	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C5F13_04135	ENOG4108JA2	transcriptioN-repair coupling factor
C5F13_04140	ENOG4105EAC	phosphoserine phosphatase
C5F13_04145	ENOG4105F04	LysR family Transcriptional regulator
C5F13_04155	ENOG4105C7K	acetolactate synthase
C5F13_04160	ENOG4105CHR	reductase
C5F13_04170	ENOG4108ESX	Receptor
C5F13_04175	ENOG4108ESX	Receptor
C5F13_04185	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C5F13_04190	ENOG4105C8S	subunit m
C5F13_04200	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C5F13_04205	ENOG4105DF2	NADH dehydrogenase subunit j
C5F13_04210	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C5F13_04215	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C5F13_04220	ENOG4108IEH	NADH dehydrogenase subunit g
C5F13_04235	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C5F13_04240	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C5F13_04245	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C5F13_04250	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C5F13_04255	ENOG4108Z9W	Outer membrane porin
C5F13_04285	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C5F13_04295	ENOG4105CBD	Diacylglycerol kinase
C5F13_04300	ENOG4105DUM	transcriptional regulator, lysR family
C5F13_04305	ENOG4105C94	Transporter
C5F13_04315	ENOG4105KVH	Transcriptional regulator
C5F13_04320	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C5F13_04325	ENOG4105BZS	acriflavin resistance protein
C5F13_04330	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C5F13_04340	ENOG41090JD	Blue (Type 1) copper domain protein
C5F13_04360	ENOG4105CJP	fad dependent oxidoreductase
C5F13_04380	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
C5F13_04385	ENOG4105C28	cystathionine
C5F13_04390	ENOG4107NQ8	LysR family Transcriptional regulator
C5F13_04395	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C5F13_04425	ENOG4105DV9	Methylaspartate ammonia-lyase
C5F13_04435	ENOG4105C94	Transporter
C5F13_04450	ENOG4105CP7	Triose-phosphate isomerase
C5F13_04470	ENOG4105C7B	Threonine dehydratase
C5F13_04490	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C5F13_04505	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C5F13_04510	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C5F13_04515	ENOG4108ZP8	Acetolactate synthase small subunit
C5F13_04520	ENOG4105C7K	acetolactate synthase
C5F13_04535	ENOG4108JJ7	ABC transporter
C5F13_04540	ENOG4105FQ6	thiopurine methyltransferase
C5F13_04560	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
C5F13_04580	ENOG4105DHT	Metal Dependent Phosphohydrolase
C5F13_04595	ENOG4107QSA	Oxaloacetate decarboxylase
C5F13_04615	ENOG4105FDP	GntR family transcriptional regulator
C5F13_04620	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C5F13_04670	ENOG4108JJ7	ABC transporter
C5F13_04680	ENOG4105CPC	Aldo Keto reductase
C5F13_04695	ENOG4108R1E	Serine threonine protein phosphatase 1
C5F13_04700	ENOG4108JQC	penicillin-binding protein 1A
C5F13_04720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C5F13_04730	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C5F13_04735	ENOG4108KB2	LysR family Transcriptional regulator
C5F13_04765	ENOG4105F27	Major Facilitator
C5F13_04770	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C5F13_04775	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C5F13_04780	ENOG4105UYK	outer membrane protein a
C5F13_04785	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C5F13_04790	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C5F13_04800	ENOG4105EVN	Prephenate dehydrogenase
C5F13_04805	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C5F13_04810	ENOG4105CAT	Cytidine monophosphate kinase
C5F13_04815	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C5F13_04830	ENOG4105CFV	Tetratricopeptide repeat protein
C5F13_04835	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C5F13_04840	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
C5F13_04845	ENOG4105KQC	Competence protein
C5F13_04855	ENOG4105C6T	cysteine synthase
C5F13_04860	ENOG4105CVE	Lytic murein transglycosylase
C5F13_04870	ENOG4105BZJ	Electron transfer flavoprotein
C5F13_04875	ENOG4105C10	Electron transfer flavoprotein
C5F13_04880	ENOG4105CSU	acyl-Coa dehydrogenase
C5F13_04885	ENOG4105D3R	alkyl hydroperoxide reductase
C5F13_04890	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C5F13_04905	ENOG4108IJ6	ABC transporter
C5F13_04940	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C5F13_04945	ENOG4105P8F	nudix hydrolase
C5F13_04955	ENOG4105CPC	Aldo Keto reductase
C5F13_04970	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
C5F13_04975	ENOG4105FE9	pseudouridine synthase
C5F13_04980	ENOG4105JQN	Transcriptional regulator
C5F13_04990	ENOG4105BZS	acriflavin resistance protein
C5F13_04995	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C5F13_05010	ENOG4105DGW	oligopeptidase A
C5F13_05020	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C5F13_05025	ENOG4105BZU	Histidine kinase
C5F13_05030	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C5F13_05035	ENOG4107QSN	dihydrolipoamide acetyltransferase
C5F13_05040	ENOG4107QN2	dihydrolipoyl dehydrogenase
C5F13_05045	ENOG4105I03	Flagellin
C5F13_05055	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C5F13_05060	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C5F13_05065	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C5F13_05070	ENOG4105BZA	Phosphoglycerate kinase
C5F13_05075	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C5F13_05080	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C5F13_05095	ENOG4108SHQ	Glutathione S-transferase
C5F13_05125	ENOG4108UMN	azlc family
C5F13_05135	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C5F13_05145	ENOG4105DR5	peptidase
C5F13_05155	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C5F13_05165	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C5F13_05170	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
C5F13_05175	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
C5F13_05180	ENOG4107RD7	Flagellar Motor Protein, MotA
C5F13_05185	ENOG4105ER2	Ompa motb domain protein
C5F13_05195	ENOG4105CBS	Chea signal transduction histidine kinase
C5F13_05200	ENOG4108V3W	Chemotaxis protein, CheW
C5F13_05205	ENOG4105C8Q	Methyl-accepting chemotaxis
C5F13_05215	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C5F13_05220	ENOG4108VYJ	response regulator receiver protein
C5F13_05225	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
C5F13_05250	ENOG4107SET	aldo keto reductase
C5F13_05260	ENOG4108JU5	Magnesium and cobalt efflux protein
C5F13_05265	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C5F13_05270	ENOG4105C9A	Phoh family
C5F13_05275	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C5F13_05290	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C5F13_05295	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C5F13_05300	ENOG4105VIE	preprotein translocase, subunit YajC
C5F13_05305	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C5F13_05310	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C5F13_05315	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
C5F13_05320	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C5F13_05350	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C5F13_05375	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
C5F13_05380	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
C5F13_05385	ENOG4105CHM	Aminotransferase
C5F13_05395	ENOG4105C6K	Malic enzyme
C5F13_05420	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C5F13_05425	ENOG4105E2Z	phosphate ABC transporter (Permease
C5F13_05430	ENOG4105C8U	phosphate abc transporter
C5F13_05435	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C5F13_05445	ENOG4105C9X	ppx gppa phosphatase
C5F13_05455	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C5F13_05465	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C5F13_05470	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
C5F13_05475	ENOG4105HBR	Rna-binding protein
C5F13_05505	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C5F13_05520	ENOG4107S2Z	UPF0761 membrane protein
C5F13_05530	ENOG4105CNG	UPF0061 protein
C5F13_05535	ENOG4106WF9	DNA-binding transcriptional regulator TorR
C5F13_05540	ENOG4105BZU	Histidine kinase
C5F13_05550	ENOG4105C0Z	ABC transporter
C5F13_05570	ENOG4108IV0	ABC, transporter
C5F13_05575	ENOG4108IQE	Amp-dependent synthetase and ligase
C5F13_05590	ENOG4105CRK	lysyL-tRNA synthetase
C5F13_05595	ENOG410904N	short-chain dehydrogenase reductase
C5F13_05605	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C5F13_05620	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C5F13_05625	ENOG4105F8V	Hydrolase, tatD family
C5F13_05650	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C5F13_05660	ENOG4105DB7	PHP domain protein
C5F13_05680	ENOG4105X0I	Fimbrial
C5F13_05685	ENOG4105C6K	Malic enzyme
C5F13_05690	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C5F13_05695	ENOG4108YXU	transcriptional regulator AsnC family
C5F13_05705	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C5F13_05710	ENOG4105C7S	Dehydrogenase
C5F13_05715	ENOG4107QN2	dihydrolipoyl dehydrogenase
C5F13_05720	ENOG4105D6Z	AFG1 family ATPase
C5F13_05725	ENOG4105CHR	reductase
C5F13_05730	ENOG4107RSM	transcriptional regulator
C5F13_05745	ENOG4105CHR	reductase
C5F13_05765	ENOG4105C31	Tryptophanyl-tRNA synthetase
C5F13_05770	ENOG4105BZM	domain protein
C5F13_05775	ENOG4105DVT	helicase
C5F13_05785	ENOG4105C34	Pseudouridine synthase
C5F13_05790	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C5F13_05795	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
C5F13_05800	ENOG4105CHR	reductase
C5F13_05805	ENOG4108NVM	synthesis repressor PhaR
C5F13_05830	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C5F13_05855	ENOG4105DIA	mandelate racemase muconate lactonizing
C5F13_05860	ENOG4105DDW	LysR family Transcriptional regulator
C5F13_05865	ENOG4105CHR	reductase
C5F13_05870	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C5F13_05885	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C5F13_05900	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C5F13_05930	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
C5F13_05955	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C5F13_05960	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_05965	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
C5F13_05970	ENOG4108ETH	Formylglycinamide ribotide synthetase
C5F13_05975	ENOG4108QZZ	filamentous hemagglutinin
C5F13_06005	ENOG4108S8N	class II Aldolase
C5F13_06010	ENOG4105CH5	extracellular solute-binding protein, family 7
C5F13_06020	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C5F13_06025	ENOG4108YZN	class I peptide chain release factor
C5F13_06045	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C5F13_06100	ENOG4105E98	transcriptional regulator DeoR family
C5F13_06105	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_06115	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
C5F13_06140	ENOG4105EW9	transcriptional regulator AsnC family
C5F13_06145	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C5F13_06150	ENOG4107RH8	nuclease SbcCD subunit D
C5F13_06190	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C5F13_06195	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C5F13_06210	ENOG4105CAF	HipA N-terminal domain protein
C5F13_06235	ENOG4105CI2	imidazolone-5-propionate hydrolase
C5F13_06250	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C5F13_06285	ENOG4105CY0	Metallo-Beta-Lactamase
C5F13_06305	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
C5F13_06310	ENOG4105ECQ	AraC Family Transcriptional Regulator
C5F13_06315	ENOG4105ETT	transcriptional Regulator, LysR family
C5F13_06335	ENOG4105DXI	Major Facilitator superfamily
C5F13_06370	ENOG4105DEF	Extracellular solute-binding protein, family 5
C5F13_06380	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C5F13_06385	ENOG4108JQ6	ABC transporter
C5F13_06390	ENOG4107KJX	Transcriptional regulator
C5F13_06420	ENOG4108KF1	Membrane
C5F13_06435	ENOG4106R49	Methyltransferase
C5F13_06450	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C5F13_06460	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C5F13_06475	ENOG4105VJV	50s ribosomal protein L35
C5F13_06480	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C5F13_06485	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C5F13_06490	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C5F13_06495	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C5F13_06560	ENOG4105CXT	aspartate transcarbamylase
C5F13_06565	ENOG4105DH7	May be involved in recombination (By similarity)
C5F13_06575	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_06580	ENOG4105ETT	transcriptional Regulator, LysR family
C5F13_06600	ENOG4105CHR	reductase
C5F13_06610	ENOG4107RCV	ABC transporter, permease
C5F13_06615	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_06620	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C5F13_06625	ENOG4105CSH	Transporter
C5F13_06630	ENOG4105DHQ	Histidine kinase
C5F13_06640	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C5F13_06645	ENOG4108004	Modulates RecA activity (By similarity)
C5F13_06650	ENOG4105DZ2	Transcriptional regulator
C5F13_06655	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C5F13_06665	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C5F13_06670	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C5F13_06675	ENOG4108ZCF	integral membrane protein
C5F13_06680	ENOG4108ZCF	integral membrane protein
C5F13_06685	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C5F13_06705	ENOG4105F0N	pyrophosphate phospho-hydrolase
C5F13_06770	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C5F13_06775	ENOG4105DG4	malate L-lactate dehydrogenase
C5F13_06780	ENOG4108M0I	Transcriptional regulator
C5F13_06790	ENOG4105DDR	sarcosine oxidase (Beta subunit)
C5F13_06795	ENOG4105WIU	sarcosine oxidase delta subunit
C5F13_06800	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C5F13_06835	ENOG4105D4A	Cell wall formation (By similarity)
C5F13_06840	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C5F13_06845	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C5F13_06850	ENOG41090R7	Ferric uptake
C5F13_06855	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C5F13_06860	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C5F13_06865	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C5F13_06870	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C5F13_06880	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5F13_06890	ENOG4105CFG	Acts as a chaperone (By similarity)
C5F13_06920	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C5F13_06965	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
C5F13_06975	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C5F13_06980	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C5F13_06985	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C5F13_07000	ENOG4107QN1	sodium solute
C5F13_07020	ENOG4105C98	muts2 protein
C5F13_07025	ENOG4105C3M	thioredoxin reductase
C5F13_07030	ENOG4105CNU	cell division protein FtsK
C5F13_07035	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
C5F13_07040	ENOG4105D1H	recombination factor protein RarA
C5F13_07045	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C5F13_07070	ENOG4105BZU	Histidine kinase
C5F13_07085	ENOG4105CNM	Receptor
C5F13_07090	ENOG4108RWP	Major Facilitator Superfamily protein
C5F13_07130	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C5F13_07135	ENOG4105DTD	Dehydrogenase
C5F13_07145	ENOG4105D1Q	UPF0246 protein
C5F13_07160	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
C5F13_07170	ENOG4108UHJ	MAF-like protein
C5F13_07175	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
C5F13_07180	ENOG4105VGS	50s ribosomal protein l32
C5F13_07185	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C5F13_07190	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C5F13_07195	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C5F13_07200	ENOG4105CHR	reductase
C5F13_07205	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C5F13_07210	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C5F13_07220	ENOG4105EMN	RNA polymerase sigma factor
C5F13_07235	ENOG4105C0H	protease
C5F13_07240	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C5F13_07245	ENOG4105C3F	Signal peptidase i
C5F13_07250	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C5F13_07255	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C5F13_07260	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
C5F13_07270	ENOG4105C6T	cysteine synthase
C5F13_07290	ENOG4108MN8	Membrane
C5F13_07300	ENOG4105MYG	DNA polymerase iii, chi subunit
C5F13_07305	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C5F13_07315	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
C5F13_07325	ENOG4105C26	Dehydrogenase
C5F13_07330	ENOG4107R11	Transcriptional regulator
C5F13_07345	ENOG4105K4H	Nlp p60 protein
C5F13_07355	ENOG4108ZJF	Glcg protein
C5F13_07365	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C5F13_07370	ENOG4108Q5Y	Membrane
C5F13_07375	ENOG4105C5W	Aldolase
C5F13_07390	ENOG4105CMR	udp-glucose 4-epimerase
C5F13_07395	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C5F13_07420	ENOG4105D44	asparaginase
C5F13_07425	ENOG4108JQ6	ABC transporter
C5F13_07430	ENOG4105DEF	Extracellular solute-binding protein, family 5
C5F13_07440	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C5F13_07465	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C5F13_07480	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C5F13_07485	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C5F13_07515	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C5F13_07525	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C5F13_07545	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C5F13_07550	ENOG4108YXA	Membrane
C5F13_07555	ENOG4105DXD	2-methylcitrate dehydratase
C5F13_07560	ENOG4105C7F	AcnD-accessory protein PrpF
C5F13_07565	ENOG4108I0Z	Aconitate hydratase
C5F13_07570	ENOG4105BZN	citrate synthase
C5F13_07580	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C5F13_07585	ENOG4105FDP	GntR family transcriptional regulator
C5F13_07590	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
C5F13_07595	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
C5F13_07605	ENOG4105E33	succinate dehydrogenase
C5F13_07610	ENOG41060IS	Flavinator of succinate dehydrogenase
C5F13_07615	ENOG4105BZN	citrate synthase
C5F13_07630	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_07640	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C5F13_07645	ENOG4105CV6	ABC transporter, permease
C5F13_07655	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
C5F13_07660	ENOG4107RUE	extracellular solute-binding protein family 1
C5F13_07665	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_07670	ENOG4105F38	ABC transporter, permease
C5F13_07675	ENOG4105D38	putrescine abc transporter
C5F13_07685	ENOG4108RB4	3-methyladenine DNA glycosylase
C5F13_07700	ENOG4105CSU	acyl-Coa dehydrogenase
C5F13_07705	ENOG4105E66	phosphoriboisomerase A
C5F13_07710	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C5F13_07715	ENOG4105HSS	phospholipase C
C5F13_07720	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
C5F13_07725	ENOG4108EKC	n-acetylglutamate synthase
C5F13_07730	ENOG4105CQ7	ATP-dependent helicase
C5F13_07740	ENOG4105C0B	DNA polymerase III (alpha subunit)
C5F13_07745	ENOG4105CPK	Glycosyl transferase (Group 1
C5F13_07750	ENOG4107BJW	polysaccharide deacetylase
C5F13_07755	ENOG4106WTF	Glycosyl transferase, family 2
C5F13_07760	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C5F13_07765	ENOG4105DIJ	Phosphoethanolamine transferase
C5F13_07780	ENOG4105KRS	Proteinase inhibitor
C5F13_07790	ENOG4105XA0	heptosyltransferase ii
C5F13_07795	ENOG4105BZ1	(ABC) transporter
C5F13_07810	ENOG4105CQC	Prephenate dehydratase
C5F13_07815	ENOG4105C03	ribonuclease
C5F13_07855	ENOG4108P8G	outer membrane autotransporter barrel
C5F13_07860	ENOG4108Z03	MAF-like protein
C5F13_07865	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C5F13_07870	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C5F13_07875	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C5F13_07880	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C5F13_07885	ENOG4105C12	Phosphoribosylglycinamide synthetase
C5F13_07890	ENOG4105CDY	transcriptional regulatory protein
C5F13_07895	ENOG4105D7A	ATP-binding protein
C5F13_07900	ENOG4105BZG	amino acid carrier protein
C5F13_07905	ENOG4105C8Y	Acetylornithine aminotransferase
C5F13_07915	ENOG4105C26	Dehydrogenase
C5F13_07925	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
C5F13_07935	ENOG4105K8K	Cupin 2, conserved barrel
C5F13_07940	ENOG4108JPW	Aminotransferase
C5F13_07955	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C5F13_07965	ENOG4105DEF	Extracellular solute-binding protein, family 5
C5F13_07975	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C5F13_07980	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C5F13_07985	ENOG4105CW7	secretion protein, HlyD family
C5F13_07995	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C5F13_08005	ENOG4106UX7	integral membrane protein
C5F13_08010	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C5F13_08015	ENOG4105D0M	Protease HtpX homolog
C5F13_08025	ENOG4105KHC	sulfurtransferase
C5F13_08035	ENOG4105DUM	transcriptional regulator, lysR family
C5F13_08040	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_08050	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
C5F13_08080	ENOG4105C2W	permease
C5F13_08085	ENOG4105C8Q	Methyl-accepting chemotaxis
C5F13_08090	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C5F13_08250	ENOG4105EMN	RNA polymerase sigma factor
C5F13_08280	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C5F13_08285	ENOG4105JGF	anti-sigma regulatory factor serine threonine protein kinase
C5F13_08290	ENOG41083UI	stage II sporulation protein
C5F13_08295	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C5F13_08335	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C5F13_08375	ENOG41080RH	Thioredoxin
C5F13_08385	ENOG4105C7N	Xanthine uracil vitamin C permease
C5F13_08390	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C5F13_08400	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C5F13_08405	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
C5F13_08410	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C5F13_08415	ENOG4108K5P	(LipO)protein
C5F13_08435	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C5F13_08450	ENOG4105EHV	domain protein
C5F13_08460	ENOG4105D6S	protein involved in catabolism of external DNA
C5F13_08465	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
C5F13_08470	ENOG4105EIN	peptidylprolyl cis-trans isomerase
C5F13_08475	ENOG4108UJV	acyl-CoA thioesterase i
C5F13_08480	ENOG4108I0Y	(ABC) transporter
C5F13_08495	ENOG4105K3G	Periplasmic Protein
C5F13_08505	ENOG4105VDW	Csbd family
C5F13_08510	ENOG4105D9M	gamma-glutamylcysteine synthetase
C5F13_08515	ENOG4107RRY	Cyanophycin synthetase
C5F13_08535	ENOG4105ED9	Protein of unknown function (DUF455)
C5F13_08540	ENOG4105CVE	Lytic murein transglycosylase
C5F13_08570	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C5F13_08575	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C5F13_08580	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C5F13_08585	ENOG4105DTN	riboflavin biosynthesis protein ribF
C5F13_08590	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C5F13_08610	ENOG4105C4R	Atp-dependent dna helicase
C5F13_08615	ENOG4105PE1	Receptor
C5F13_08620	ENOG4105C5H	ABC transporter
C5F13_08625	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C5F13_08630	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C5F13_08635	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C5F13_08670	ENOG4105VEQ	Cold shock protein
C5F13_08680	ENOG4105VEQ	Cold shock protein
C5F13_08685	ENOG4108TEB	UPF0114 protein
C5F13_08690	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C5F13_08695	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C5F13_08700	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C5F13_08705	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C5F13_08710	ENOG4105CN8	Transcriptional regulator
C5F13_08715	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_08720	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C5F13_08730	ENOG4108UKI	Enoyl-CoA hydratase
C5F13_08745	ENOG4105CHR	reductase
C5F13_08765	ENOG4107QNJ	CoA-transferase subunit B
C5F13_08785	ENOG4105WH1	Two component transcriptional regulator luxr family
C5F13_08800	ENOG4107QP8	phosphohexose isomerase
C5F13_08805	ENOG4105D7W	serine acetyltransferase
C5F13_08815	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C5F13_08820	ENOG4105ECY	inositol monophosphatase
C5F13_08825	ENOG4105C26	Dehydrogenase
C5F13_08830	ENOG4108JPW	Aminotransferase
C5F13_08845	ENOG4105C4R	Atp-dependent dna helicase
C5F13_08850	ENOG4105D7N	magnesium and cobalt transport protein CorA
C5F13_08860	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
C5F13_08870	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C5F13_08875	ENOG4108JQ6	ABC transporter
C5F13_08905	ENOG4105BZU	Histidine kinase
C5F13_08975	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C5F13_08990	ENOG4105EMN	RNA polymerase sigma factor
C5F13_09000	ENOG4105XUA	cytochrome c
C5F13_09005	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C5F13_09020	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C5F13_09025	ENOG4107QM5	aconitate hydratase
C5F13_09055	ENOG41090EK	ompa motb domain protein
C5F13_09065	ENOG4107QIJ	Aconitate hydratase 2
C5F13_09090	ENOG4108594	Permease of the drug metabolite transporter
C5F13_09095	ENOG4105P69	integral membrane protein
C5F13_09115	ENOG4105CMU	LysR family (Transcriptional regulator
C5F13_09120	ENOG4105CYC	Transferase
C5F13_09130	ENOG4108MGI	Transcriptional regulator
C5F13_09175	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
C5F13_09180	ENOG4105EUF	amidase EC 3.5.1.4
C5F13_09190	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C5F13_09205	ENOG4105C8T	Leucyl-tRNA synthetase
C5F13_09215	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C5F13_09240	ENOG4105W0E	50S ribosomal protein L33
C5F13_09245	ENOG4105KDC	50s ribosomal protein l28
C5F13_09250	ENOG4105C2C	drug resistance transporter, Bcr CflA
C5F13_09270	ENOG4108HQS	Glycine betaine
C5F13_09275	ENOG4108IJ7	Glycine betaine
C5F13_09285	ENOG4105CHU	acetyl-coa acetyltransferase
C5F13_09295	ENOG4105DRR	Transcriptional regulator, GntR family
C5F13_09305	ENOG4105E39	Enoyl-CoA hydratase
C5F13_09320	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C5F13_09335	ENOG4105D5T	phosphonate abc transporter
C5F13_09340	ENOG4105F4R	Transcriptional regulator mode
C5F13_09360	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C5F13_09365	ENOG4105BZS	acriflavin resistance protein
C5F13_09375	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C5F13_09380	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C5F13_09385	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
C5F13_09390	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C5F13_09395	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C5F13_09405	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C5F13_09430	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_09440	ENOG4105FUY	alpha subunit
C5F13_09445	ENOG4108SBK	dioxygenase, subunit beta
C5F13_09450	ENOG4105E39	Enoyl-CoA hydratase
C5F13_09455	ENOG4105CHR	reductase
C5F13_09460	ENOG4107Z7P	Ferredoxin
C5F13_09465	ENOG410846T	CoA-transferase family III
C5F13_09475	ENOG4105DZS	Phenylacetate-CoA ligase
C5F13_09480	ENOG4105CHU	acetyl-coa acetyltransferase
C5F13_09500	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C5F13_09525	ENOG4105VIG	Sec-independent protein translocase protein TatC
C5F13_09600	ENOG4105DC8	reductase
C5F13_09625	ENOG4105EXG	Transcriptional regulator
C5F13_09650	ENOG4105CF7	AraC family transcriptional regulator
C5F13_09700	ENOG4105BZ1	(ABC) transporter
C5F13_09725	ENOG4105CHH	sulfate transporter
C5F13_09760	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
C5F13_09765	ENOG4107ZY0	Phenazine biosynthesis-like protein
C5F13_09775	ENOG4106BRA	Membrane
C5F13_09790	ENOG4105C26	Dehydrogenase
C5F13_09795	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C5F13_09815	ENOG4105VAW	lrga family
C5F13_09820	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C5F13_09830	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C5F13_09835	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C5F13_09900	ENOG4105DA5	(ABC) transporter
C5F13_09905	ENOG4105E3A	(ABC) transporter
C5F13_09910	ENOG4105IPI	Membrane
C5F13_09955	ENOG4105VCC	30S ribosomal protein S21
C5F13_09960	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C5F13_09965	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C5F13_09970	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
C5F13_09975	ENOG4105EPW	hflc protein
C5F13_09980	ENOG4107QJR	hflk protein
C5F13_09985	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C5F13_09990	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C5F13_09995	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C5F13_10000	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C5F13_10005	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C5F13_10010	ENOG4105N21	Membrane
C5F13_10015	ENOG4105CUT	histidyl-tRNA synthetase
C5F13_10020	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C5F13_10030	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C5F13_10035	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C5F13_10040	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C5F13_10055	ENOG4105DHQ	Histidine kinase
C5F13_10080	ENOG4105C9B	Cysteine desulfurase
C5F13_10085	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C5F13_10090	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C5F13_10095	ENOG4105K5M	30s ribosomal protein S16
C5F13_10105	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
C5F13_10110	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C5F13_10155	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_10160	ENOG4108JQ6	ABC transporter
C5F13_10190	ENOG4105C5Q	Transcriptional regulator
C5F13_10200	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C5F13_10210	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C5F13_10245	ENOG4105CGU	Enoyl-CoA hydratase
C5F13_10260	ENOG4105WVQ	Fe-S assembly protein IscX
C5F13_10265	ENOG4108ZIT	Ferredoxin, 2FE-2S
C5F13_10270	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
C5F13_10275	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
C5F13_10280	ENOG4108Z4V	iron-sulfur cluster assembly
C5F13_10285	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
C5F13_10290	ENOG4105C3J	Cysteine desulfurase
C5F13_10295	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C5F13_10305	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C5F13_10310	ENOG4105CGF	Aromatic amino acid aminotransferase
C5F13_10315	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C5F13_10330	ENOG4108VHT	MarR family transcriptional regulator
C5F13_10350	ENOG4107BJW	polysaccharide deacetylase
C5F13_10355	ENOG4105CND	Glycosyl transferase, family 2
C5F13_10365	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C5F13_10390	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
C5F13_10400	ENOG4105K4P	CoA-binding domain protein
C5F13_10405	ENOG4107HP6	Transcriptional regulator
C5F13_10410	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C5F13_10420	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_10430	ENOG4105F38	ABC transporter, permease
C5F13_10445	ENOG4105RQF	LysR family Transcriptional regulator
C5F13_10455	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C5F13_10460	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
C5F13_10465	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C5F13_10470	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C5F13_10475	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_10480	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
C5F13_10485	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
C5F13_10510	ENOG4105CFH	Aspartokinase
C5F13_10515	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C5F13_10525	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C5F13_10535	ENOG4105C8N	cysteinyl-tRNA synthetase
C5F13_10550	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C5F13_10555	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C5F13_10560	ENOG4105EE5	Membrane protein terC
C5F13_10565	ENOG4105ECY	inositol monophosphatase
C5F13_10585	ENOG4105D64	Mechanosensitive ion channel
C5F13_10635	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C5F13_10650	ENOG4108YH7	hemolysin
C5F13_10655	ENOG41074HU	Fimbrial adhesin
C5F13_10665	ENOG4105GQR	Chaperone
C5F13_10675	ENOG4108QZZ	filamentous hemagglutinin
C5F13_10680	ENOG4108WQH	regulatoR
C5F13_10685	ENOG4105BZU	Histidine kinase
C5F13_10695	ENOG4105CFM	UPF0317 protein
C5F13_10755	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_10765	ENOG4105C7K	acetolactate synthase
C5F13_10770	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
C5F13_10780	ENOG4105D82	Glutamate dehydrogenase
C5F13_10790	ENOG4105CDA	abc transporter atp-binding protein
C5F13_10800	ENOG4106PMH	Extracellular solute-binding protein family 3
C5F13_10815	ENOG4105F8V	Hydrolase, tatD family
C5F13_10820	ENOG4105C6E	dna polymerase iii
C5F13_10825	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C5F13_10830	ENOG4105HHA	aminodeoxychorismate lyase
C5F13_10835	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C5F13_10850	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C5F13_10855	ENOG4105KPV	Transcriptional regulator
C5F13_10860	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C5F13_10895	ENOG4105C5H	ABC transporter
C5F13_10900	ENOG4105CH5	extracellular solute-binding protein, family 7
C5F13_10910	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_10915	ENOG4105CGU	Enoyl-CoA hydratase
C5F13_10920	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C5F13_10925	ENOG4108Z6B	deaminase
C5F13_10950	ENOG4105W4C	monovalent cation H antiporter subunit F
C5F13_10955	ENOG4105SC1	monovalent cation H antiporter subunit E
C5F13_10960	ENOG4107R4Z	monovalent cation h antiporter subunit d
C5F13_10965	ENOG4108ZE9	Monovalent cation H antiporter subunit C
C5F13_10970	ENOG4105D65	subunit l
C5F13_10995	ENOG4105CHR	reductase
C5F13_11025	ENOG4105CAU	Arsenical resistance protein, ArsH
C5F13_11070	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
C5F13_11075	ENOG4105ERH	Fumarylacetoacetate hydrolase
C5F13_11105	ENOG4108K3A	Glutathione S-transferase
C5F13_11115	ENOG4105W08	virulence gene repressor rsal
C5F13_11125	ENOG4105WH1	Two component transcriptional regulator luxr family
C5F13_11150	ENOG4105ENH	Sulfatase
C5F13_11185	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C5F13_11210	ENOG4108ZCF	integral membrane protein
C5F13_11225	ENOG4105C0Z	ABC transporter
C5F13_11230	ENOG4108IV0	ABC, transporter
C5F13_11255	ENOG4108W6C	Dehydrogenase
C5F13_11265	ENOG41084CK	capsule polysaccharide
C5F13_11270	ENOG4105E12	capsule polysaccharide
C5F13_11280	ENOG4107QQG	Dehydrogenase
C5F13_11295	ENOG4107TAE	Glycosyl transferase (Group 1
C5F13_11315	ENOG4105K64	Glycosyl transferase, family 2
C5F13_11340	ENOG4105C26	Dehydrogenase
C5F13_11345	ENOG4105JQN	Transcriptional regulator
C5F13_11350	ENOG4105C5Q	Transcriptional regulator
C5F13_11355	ENOG4105CB5	ATP-dependent DNA helicase recG
C5F13_11360	ENOG4105KME	endoribonuclease L-psp
C5F13_11370	ENOG4105CV8	reductase
C5F13_11380	ENOG4105HEI	LysR family (Transcriptional regulator
C5F13_11385	ENOG4105DP0	ferredoxin-NADP reductase
C5F13_11390	ENOG4107QKW	extracellular solute-binding protein family 1
C5F13_11395	ENOG4107RCV	ABC transporter, permease
C5F13_11400	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_11410	ENOG4105EUB	pirin domain protein
C5F13_11420	ENOG4105EQ1	Transcriptional regulator
C5F13_11425	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C5F13_11430	ENOG4105CUX	Signal transduction histidine kinase
C5F13_11435	ENOG4105C5F	glutamine synthetase
C5F13_11440	ENOG4105CSA	Coproporphyrinogen iii oxidase
C5F13_11450	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C5F13_11455	ENOG4105BZU	Histidine kinase
C5F13_11460	ENOG4105C8Q	Methyl-accepting chemotaxis
C5F13_11465	ENOG4105DUM	transcriptional regulator, lysR family
C5F13_11475	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C5F13_11480	ENOG4105DSJ	YicC domain protein
C5F13_11500	ENOG4105FYV	Amp nucleosidase
C5F13_11505	ENOG4105K4H	Nlp p60 protein
C5F13_11510	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C5F13_11515	ENOG41090Y2	cytochrome C
C5F13_11525	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C5F13_11530	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C5F13_11535	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C5F13_11540	ENOG4105CDA	abc transporter atp-binding protein
C5F13_11545	ENOG4105E5Q	amino acid AbC transporter
C5F13_11550	ENOG4107R0W	ABC transporter
C5F13_11565	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C5F13_11570	ENOG4105GJM	(LipO)protein
C5F13_11580	ENOG4105EZE	Cupin 4 family protein
C5F13_11585	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C5F13_11590	ENOG4105WKW	Pfam:DUF1458
C5F13_11640	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C5F13_11645	ENOG4105CGZ	zinc metallopeptidase
C5F13_11670	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C5F13_11675	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C5F13_11680	ENOG4107QMP	dna polymerase iii subunits gamma and tau
C5F13_11690	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C5F13_11700	ENOG4107RGD	Major Facilitator superfamily
C5F13_11710	ENOG41061WM	D-Alanyl-D-Alanine
C5F13_11725	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C5F13_11730	ENOG4108Z66	YbaK ebsC protein
C5F13_11735	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C5F13_11740	ENOG4105ETT	transcriptional Regulator, LysR family
C5F13_11745	ENOG4105C7K	acetolactate synthase
C5F13_11750	ENOG4105C1G	acyl-Coa dehydrogenase
C5F13_11765	ENOG4105CDA	abc transporter atp-binding protein
C5F13_11770	ENOG4105E5Q	amino acid AbC transporter
C5F13_11780	ENOG4105CYW	agmatinase
C5F13_11785	ENOG4108FUF	Transcriptional regulator, IclR family
C5F13_11795	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C5F13_11800	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C5F13_11805	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C5F13_11810	ENOG4105RXK	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
C5F13_11820	ENOG4105WJ3	XRE family Transcriptional regulator
C5F13_11825	ENOG4105RT5	Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation
C5F13_11830	ENOG4105C8V	SAICAR synthetase
C5F13_11840	ENOG4105D2N	Aldolase
C5F13_11860	ENOG4105IW1	AmiS UreI transporter
C5F13_11910	ENOG4105CIF	Ornithine Cyclodeaminase
C5F13_11925	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C5F13_11930	ENOG41080Z8	PHOSPHOCARRIER protein
C5F13_11940	ENOG4105D7Z	glutathione synthase
C5F13_11945	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C5F13_11950	ENOG4105C22	threonyL-tRNA synthetase
C5F13_11955	ENOG4108T94	DNA-binding transcriptional activator BglJ
C5F13_11975	ENOG4105BZU	Histidine kinase
C5F13_11995	ENOG4105D1Q	UPF0246 protein
C5F13_12010	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C5F13_12015	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_12025	ENOG4105CH5	extracellular solute-binding protein, family 7
C5F13_12030	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C5F13_12040	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C5F13_12045	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C5F13_12050	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C5F13_12055	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C5F13_12065	ENOG4108JJB	ABC transporter
C5F13_12100	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C5F13_12135	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C5F13_12140	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C5F13_12145	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
C5F13_12150	ENOG4105ERG	peptidase m48, ste24p
C5F13_12155	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C5F13_12180	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_12190	ENOG4105CVJ	phosphoglycerate mutase
C5F13_12200	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C5F13_12205	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C5F13_12210	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C5F13_12240	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C5F13_12245	ENOG4108IPT	Naphthoate synthase
C5F13_12250	ENOG4105C1G	acyl-Coa dehydrogenase
C5F13_12260	ENOG4108Z1B	Cyclase dehydrase
C5F13_12270	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C5F13_12275	ENOG4105BZU	Histidine kinase
C5F13_12280	ENOG4107QX8	SPFH domain, Band 7 family protein
C5F13_12295	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C5F13_12300	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C5F13_12305	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C5F13_12315	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C5F13_12320	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5F13_12330	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C5F13_12335	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5F13_12340	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
C5F13_12345	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5F13_12350	ENOG4105DZP	Membrane-associated zinc metalloprotease
C5F13_12355	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C5F13_12360	ENOG4105KNE	Phosphatidate cytidylyltransferase
C5F13_12365	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C5F13_12370	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C5F13_12375	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C5F13_12380	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C5F13_12385	ENOG4105CE9	30S ribosomal protein S2
C5F13_12390	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C5F13_12395	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C5F13_12410	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C5F13_12425	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C5F13_12435	ENOG4105DTS	flagellar hook-associated
C5F13_12440	ENOG4105MQ3	flagellar protein FliS
C5F13_12460	ENOG4105D00	flagellar biosynthetic protein flhB
C5F13_12470	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C5F13_12475	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C5F13_12480	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C5F13_12490	ENOG4108JIR	Flagellum-specific ATP synthase
C5F13_12515	ENOG4107ZI8	flagellar basal body-associated protein flil
C5F13_12520	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C5F13_12525	ENOG4105DD5	Flagellar motor switch protein
C5F13_12535	ENOG4105CN7	Flagellar biosynthetic protein FliP
C5F13_12540	ENOG4105VS8	Flagellar biosynthetic protein fliq
C5F13_12545	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C5F13_12555	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C5F13_12560	ENOG4105C8Q	Methyl-accepting chemotaxis
C5F13_12565	ENOG4105C8Q	Methyl-accepting chemotaxis
C5F13_12570	ENOG4105DTJ	flagellar hook-associated protein
C5F13_12575	ENOG4105E1Q	flagellar hook-associated protein
C5F13_12580	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C5F13_12585	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C5F13_12590	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C5F13_12595	ENOG4105CGA	flagellar basal-body rod protein FlgG
C5F13_12600	ENOG4108KPB	Flagellar basal-body rod protein FlgF
C5F13_12605	ENOG4105BZE	flagellar hook protein, FlgE
C5F13_12610	ENOG4105W00	Flagellar hook capping protein
C5F13_12615	ENOG4108ZC9	flagellar basal-body rod protein flgc
C5F13_12620	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C5F13_12630	ENOG4105M9M	anti-sigma28 factor FlgM
C5F13_12650	ENOG4105D00	flagellar biosynthetic protein flhB
C5F13_12665	ENOG4105E5Q	amino acid AbC transporter
C5F13_12670	ENOG4105CDA	abc transporter atp-binding protein
C5F13_12680	ENOG4108KF8	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C5F13_12685	ENOG4105CMJ	mandelate racemase muconate lactonizing
C5F13_12705	ENOG4105ETE	Transcriptional regulator (LacI family
C5F13_12715	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_12735	ENOG4108PVQ	transcriptional regulator
C5F13_12750	ENOG4105HEI	LysR family (Transcriptional regulator
C5F13_12770	ENOG4105NTW	Transcriptional regulator
C5F13_12780	ENOG4105X23	Endonuclease Exonuclease phosphatase
C5F13_12785	ENOG4105DZQ	phospholipase D Transphosphatidylase
C5F13_12835	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C5F13_12845	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C5F13_12865	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C5F13_12870	ENOG4105DFA	alanine racemase domain protein
C5F13_12875	ENOG4105CSW	GntR family transcriptional regulator
C5F13_12890	ENOG41068KF	Universal stress protein
C5F13_12895	ENOG4105CPC	Aldo Keto reductase
C5F13_12910	ENOG4108VGI	doxx family
C5F13_12940	ENOG410846T	CoA-transferase family III
C5F13_12945	ENOG4105WAP	TPR repeat-containing protein
C5F13_12965	ENOG4105CYM	Glutathione S-transferase
C5F13_12980	ENOG4105DF9	Lipoate-protein, ligase
C5F13_13005	ENOG4105D01	(LipO)protein
C5F13_13040	ENOG4105CP9	extracellular ligand-binding receptor
C5F13_13045	ENOG4108IJ9	(ABC) transporter
C5F13_13055	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
C5F13_13060	ENOG4105BZ7	extracellular solute-binding protein family 1
C5F13_13065	ENOG4105II7	pyrroline-5-carboxylate reductase
C5F13_13070	ENOG4105EX9	Membrane
C5F13_13080	ENOG4105CP9	extracellular ligand-binding receptor
C5F13_13085	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_13090	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C5F13_13095	ENOG4105C0Z	ABC transporter
C5F13_13100	ENOG4108IV0	ABC, transporter
C5F13_13105	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C5F13_13140	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C5F13_13150	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C5F13_13155	ENOG4105K63	Thioredoxin
C5F13_13160	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C5F13_13170	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C5F13_13175	ENOG4105WPN	DNA integration recombination invertion protein
C5F13_13180	ENOG4105EJQ	L-serine dehydratase
C5F13_13185	ENOG4105EAM	Na Pi-cotransporter
C5F13_13190	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
C5F13_13200	ENOG4105C2M	dna polymerase I
C5F13_13205	ENOG4108URH	decarboxylase
C5F13_13225	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C5F13_13230	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C5F13_13235	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C5F13_13240	ENOG4105CHV	Transcription elongation factor NusA
C5F13_13245	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C5F13_13250	ENOG4105FE9	pseudouridine synthase
C5F13_13255	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C5F13_13265	ENOG4105EJC	lysr family transcriptional regulator
C5F13_13275	ENOG4105CKI	cobalamin synthesis protein
C5F13_13295	ENOG4108RXX	maleylacetoacetate isomerase
C5F13_13305	ENOG4108YZY	peptidylprolyl cis-trans isomerase
C5F13_13310	ENOG4105W5Q	DNA repair protein (RadC
C5F13_13315	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
C5F13_13320	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
C5F13_13325	ENOG4105NRA	50s ribosomal protein l31 type b
C5F13_13335	ENOG4107QI1	Mate efflux family protein
C5F13_13350	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C5F13_13355	ENOG4105CP2	von willebrand factor, type a
C5F13_13375	ENOG4105CHR	reductase
C5F13_13380	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C5F13_13395	ENOG4105CVN	desaturase
C5F13_13395	ENOG4105CVN	desaturase
C5F13_13400	ENOG4107Z6W	Protein CrcB homolog
C5F13_13415	ENOG4105CJ1	ABC, transporter
C5F13_13435	ENOG4105CJ2	(LipO)protein
C5F13_13470	ENOG4105EQN	UPF0261 protein
C5F13_13480	ENOG4108P8G	outer membrane autotransporter barrel
C5F13_13500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C5F13_13505	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C5F13_13520	ENOG4108YZ4	nudix hydrolase
C5F13_13525	ENOG4105VRT	cytoplasmic protein
C5F13_13535	ENOG4108KPJ	rna polymerase sigma factor
C5F13_13540	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
C5F13_13575	ENOG4105EAB	amino acid AbC transporter
C5F13_13580	ENOG4105EAD	ABC transporter
C5F13_13585	ENOG4105DRP	amino acid AbC transporter
C5F13_13625	ENOG4108ZJI	phenylacetic acid degradation protein
C5F13_13630	ENOG4108UKI	Enoyl-CoA hydratase
C5F13_13655	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
C5F13_13660	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
C5F13_13665	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
C5F13_13670	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
C5F13_13675	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
C5F13_13685	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C5F13_13690	ENOG4105D0M	Protease HtpX homolog
C5F13_13695	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C5F13_13710	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C5F13_13715	ENOG4105DEF	Extracellular solute-binding protein, family 5
C5F13_13720	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C5F13_13725	ENOG4105DUM	transcriptional regulator, lysR family
C5F13_13750	ENOG4108YZA	Nitrogen regulatory protein pii
C5F13_13760	ENOG4105CUY	Mechanosensitive ion channel
C5F13_13765	ENOG4105CH7	arginosuccinase
C5F13_13785	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C5F13_13790	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C5F13_13795	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C5F13_13800	ENOG4108ZAF	Molybdopterin
C5F13_13810	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C5F13_13820	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
C5F13_13840	ENOG4108TZV	Membrane
C5F13_13845	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C5F13_13870	ENOG4105W1Y	Transcriptional regulator
C5F13_13890	ENOG4105CHR	reductase
C5F13_13900	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
C5F13_13905	ENOG4105CCU	oxidase (Subunit III)
C5F13_13910	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C5F13_13920	ENOG4105CSH	Transporter
C5F13_13935	ENOG4105W0Z	cytoplasmic protein
C5F13_13940	ENOG4108YZA	Nitrogen regulatory protein pii
C5F13_13955	ENOG41060BG	Tetr family transcriptional regulator
C5F13_13960	ENOG4105DCM	major facilitator superfamily
C5F13_13965	ENOG4108IV0	ABC, transporter
C5F13_13970	ENOG4105C0Z	ABC transporter
C5F13_13975	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C5F13_13980	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_13995	ENOG4105C26	Dehydrogenase
C5F13_14005	ENOG4105DY2	Paraquat-inducible protein b
C5F13_14010	ENOG4105F1S	paraquat-inducible protein a
C5F13_14015	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C5F13_14020	ENOG4108JQB	penicillin-binding protein 1C
C5F13_14030	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C5F13_14035	ENOG4105VEQ	Cold shock protein
C5F13_14045	ENOG4105CHU	acetyl-coa acetyltransferase
C5F13_14055	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C5F13_14060	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C5F13_14075	ENOG4109015	Biopolymer transport protein exbD tolR
C5F13_14080	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C5F13_14085	ENOG4105W49	UPF0434 protein
C5F13_14090	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
C5F13_14095	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C5F13_14105	ENOG4105CJR	Integral membrane protein (MviN
C5F13_14115	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
C5F13_14150	ENOG4105DG4	malate L-lactate dehydrogenase
C5F13_14170	ENOG4105D6E	homoserine dehydrogenase
C5F13_14175	ENOG4105CHM	Aminotransferase
C5F13_14180	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
C5F13_14185	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5F13_14190	ENOG4108IAB	Phoh family
C5F13_14195	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C5F13_14200	ENOG4105DHU	Bile acid
C5F13_14205	ENOG4105CDU	Replicative dna helicase
C5F13_14215	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C5F13_14220	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C5F13_14230	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C5F13_14235	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
C5F13_14240	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C5F13_14245	ENOG4105CTB	Polyprenyl synthetase
C5F13_14250	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C5F13_14280	ENOG4105CJW	magnesium transporter
C5F13_14285	ENOG4105NAU	thioesterase Superfamily protein
C5F13_14290	ENOG4105HMI	Membrane
C5F13_14295	ENOG4105DUM	transcriptional regulator, lysR family
C5F13_14300	ENOG4105CH2	amidohydrolase
C5F13_14305	ENOG4105CEY	Amp-dependent synthetase and ligase
C5F13_14320	ENOG4105ECY	inositol monophosphatase
C5F13_14330	ENOG4105CJQ	hydrolase, family 31
C5F13_14335	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C5F13_14340	ENOG4108UMI	ABC transporter, permease
C5F13_14345	ENOG4105D01	(LipO)protein
C5F13_14360	ENOG4105C0A	alcohol dehydrogenase
C5F13_14390	ENOG41073TP	transcriptional regulator
C5F13_14415	ENOG4105D56	permease protein
C5F13_14420	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
C5F13_14425	ENOG4108IJ9	(ABC) transporter
C5F13_14440	ENOG4105WEM	extracellular solute-binding protein
C5F13_14455	ENOG4108Z4X	TRANSCRIPTIONal
C5F13_14460	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C5F13_14465	ENOG41066T0	asmA family
C5F13_14475	ENOG4108XFH	Transcriptional regulator
C5F13_14480	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
C5F13_14540	ENOG4105DND	Transcriptional regulator
C5F13_14545	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C5F13_14550	ENOG4108Z9W	Outer membrane porin
C5F13_14565	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C5F13_14570	ENOG4105CSH	Transporter
C5F13_14580	ENOG4106NZI	LysR family Transcriptional regulator
C5F13_14585	ENOG4105CGF	Aromatic amino acid aminotransferase
C5F13_14590	ENOG4105EST	Metal Dependent Phosphohydrolase
C5F13_14615	ENOG4105CPQ	Dehydrogenase
C5F13_14635	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
C5F13_14645	ENOG4105CEY	Amp-dependent synthetase and ligase
C5F13_14655	ENOG4108XM1	transcriptional regulator AsnC family
C5F13_14665	ENOG4108R6K	riboflavin synthase, subunit alpha
C5F13_14670	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_14690	ENOG4105DJ2	Major Facilitator Superfamily
C5F13_14695	ENOG4107Y2X	deaminase
C5F13_14705	ENOG4105HEI	LysR family (Transcriptional regulator
C5F13_14725	ENOG4108IV0	ABC, transporter
C5F13_14740	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_14745	ENOG4107Z5Z	endoribonuclease L-PSP
C5F13_14760	ENOG41069M3	Transcriptional regulator
C5F13_14765	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C5F13_14795	ENOG4105E39	Enoyl-CoA hydratase
C5F13_14800	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_14805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_14845	ENOG4105T86	cytochrome C
C5F13_14850	ENOG4107QTF	adenylosuccinate lyase
C5F13_14855	ENOG4108U78	Glutathione S-transferase
C5F13_14865	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C5F13_14870	ENOG4105ETT	transcriptional Regulator, LysR family
C5F13_14885	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C5F13_14895	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C5F13_14905	ENOG4107RNH	Outer membrane receptor FepA
C5F13_14910	ENOG4105NIV	Esterase
C5F13_14915	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C5F13_14920	ENOG4105EU8	FAD linked oxidase domain protein
C5F13_14925	ENOG4105CQB	FAD linked oxidase domain protein
C5F13_14930	ENOG4105CQB	FAD linked oxidase domain protein
C5F13_14935	ENOG4108QZZ	filamentous hemagglutinin
C5F13_14935	ENOG4108QZZ	filamentous hemagglutinin
C5F13_14940	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C5F13_14945	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
C5F13_14995	ENOG4108K5P	(LipO)protein
C5F13_15010	ENOG4105E0K	tonB-dependent siderophore receptor
C5F13_15025	ENOG4105E18	UPF0276 protein
C5F13_15045	ENOG4105YVS	arsR family transcriptional regulator
C5F13_15050	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
C5F13_15055	ENOG4105CCU	oxidase (Subunit III)
C5F13_15060	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C5F13_15065	ENOG4105E2S	oxidase) subunit II
C5F13_15070	ENOG4108UYB	regulatoR
C5F13_15085	ENOG4105EUB	pirin domain protein
C5F13_15110	ENOG4105C5Q	Transcriptional regulator
C5F13_15145	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C5F13_15160	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C5F13_15165	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C5F13_15175	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C5F13_15190	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
C5F13_15195	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C5F13_15205	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C5F13_15210	ENOG4108UJD	30S ribosomal protein S9
C5F13_15215	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C5F13_15220	ENOG4105CH5	extracellular solute-binding protein, family 7
C5F13_15225	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
C5F13_15230	ENOG4105N42	UPF0307 protein
C5F13_15250	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
C5F13_15255	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
C5F13_15260	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
C5F13_15265	ENOG4105C1J	atp-dependent rna helicase
C5F13_15275	ENOG4105DRR	Transcriptional regulator, GntR family
C5F13_15290	ENOG4105CD5	CoA-binding domain protein
C5F13_15295	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C5F13_15310	ENOG4108YXU	transcriptional regulator AsnC family
C5F13_15325	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C5F13_15330	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C5F13_15345	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
C5F13_15350	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C5F13_15390	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C5F13_15395	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C5F13_15400	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C5F13_15405	ENOG4107QX9	Thiol disulfide interChange protein
C5F13_15410	ENOG4105DFU	Cell wall formation (By similarity)
C5F13_15415	ENOG4105IPS	esterase
C5F13_15430	ENOG4105E2X	shikimate dehydrogenase
C5F13_15450	ENOG4108XM1	transcriptional regulator AsnC family
C5F13_15455	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C5F13_15460	ENOG4105CHR	reductase
C5F13_15480	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C5F13_15485	ENOG4105DR5	peptidase
C5F13_15495	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5F13_15500	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C5F13_15505	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C5F13_15510	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
C5F13_15515	ENOG4105CPF	Cell wall formation (By similarity)
C5F13_15520	ENOG4105DFU	Cell wall formation (By similarity)
C5F13_15525	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C5F13_15535	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C5F13_15540	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C5F13_15545	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C5F13_15550	ENOG4105CJN	penicillin-binding protein
C5F13_15555	ENOG4105N8N	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C5F13_15560	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C5F13_15565	ENOG4108V6E	Cell division protein mraZ
C5F13_15575	ENOG4105C5H	ABC transporter
C5F13_15580	ENOG4105EKE	dihydroorotase
C5F13_15585	ENOG4105CH2	amidohydrolase
C5F13_15625	ENOG4105EW9	transcriptional regulator AsnC family
C5F13_15630	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
C5F13_15635	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C5F13_15640	ENOG4105W2Z	cytochrome C, class I
C5F13_15645	ENOG4105C01	Dihydroxy-acid dehydratase
C5F13_15650	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C5F13_15695	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C5F13_15700	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C5F13_15720	ENOG4108WBT	adenosyltransferase
C5F13_15735	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C5F13_15740	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C5F13_15745	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5F13_15750	ENOG4105CKI	cobalamin synthesis protein
C5F13_15755	ENOG4105MYN	Zinc uptake regulation protein
C5F13_15765	ENOG4105DIK	(ABC) transporter
C5F13_15770	ENOG4105CC5	ABC transporter
C5F13_15775	ENOG4105DSE	periplasmic solute binding protein
C5F13_15785	ENOG4105D7X	high-affinity nickel-transporter
C5F13_15790	ENOG4105UGU	tonB-dependent Receptor
C5F13_15795	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C5F13_15805	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C5F13_15810	ENOG4105D1S	lipid A biosynthesis
C5F13_15820	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C5F13_15830	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C5F13_15835	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C5F13_15840	ENOG41086DT	Membrane protein of unknown function
C5F13_15845	ENOG4105SYT	Methylenetetrahydrofolate reductase
C5F13_15855	ENOG4105DUM	transcriptional regulator, lysR family
C5F13_15865	ENOG4105CSH	Transporter
C5F13_15875	ENOG4107SC1	transglycosylase
C5F13_15880	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C5F13_15890	ENOG4105C1J	atp-dependent rna helicase
C5F13_15895	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C5F13_15905	ENOG4107RZC	phospholipase d
C5F13_15910	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
C5F13_15915	ENOG4105E0C	molybdate abc transporter
C5F13_15920	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C5F13_15975	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C5F13_15985	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C5F13_15995	ENOG4105CJP	fad dependent oxidoreductase
C5F13_16025	ENOG4108W9H	Tetr family transcriptional regulator
C5F13_16040	ENOG4108KXV	response regulator
C5F13_16090	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C5F13_16115	ENOG4105DFP	Integrase
C5F13_16120	ENOG4105C3G	gtp-binding protein
C5F13_16130	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C5F13_16135	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C5F13_16140	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C5F13_16150	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C5F13_16155	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
C5F13_16160	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
C5F13_16165	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C5F13_16190	ENOG4105F1J	Homogentisate 1,2-dioxygenase
C5F13_16200	ENOG4105E0M	Sulfatase
C5F13_16205	ENOG4105DHQ	Histidine kinase
C5F13_16210	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C5F13_16215	ENOG4105CQB	FAD linked oxidase domain protein
C5F13_16230	ENOG4107QP8	phosphohexose isomerase
C5F13_16235	ENOG4105CGN	Glycosyl transferase (Group 1
C5F13_16240	ENOG4108KMV	Glycosyl transferase (Group 1
C5F13_16245	ENOG4107XU6	Glycosyl transferase (Group 1
C5F13_16255	ENOG4105CG5	Glycosyl transferase (Group 1
C5F13_16270	ENOG4107QQG	Dehydrogenase
C5F13_16275	ENOG4107UKG	Glycosyl transferase, family 4
C5F13_16280	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
C5F13_16290	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C5F13_16300	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C5F13_16305	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C5F13_16345	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
C5F13_16350	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
C5F13_16360	ENOG4105CQM	Urea amidohydrolase subunit alpha
C5F13_16365	ENOG4105KI2	Urea amidohydrolase subunit beta
C5F13_16375	ENOG4108YZ9	Urea amidohydrolase subunit gamma
C5F13_16380	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
C5F13_16405	ENOG4108TZY	GntR Family Transcriptional Regulator
C5F13_16430	ENOG4105ED1	spovr family
C5F13_16435	ENOG4106AKX	UPF0229 protein
C5F13_16455	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_16460	ENOG4105DZS	Phenylacetate-CoA ligase
C5F13_16470	ENOG4105C1G	acyl-Coa dehydrogenase
C5F13_16480	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_16485	ENOG4108IV0	ABC, transporter
C5F13_16490	ENOG4105C0Z	ABC transporter
C5F13_16505	ENOG4105E39	Enoyl-CoA hydratase
C5F13_16570	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C5F13_16575	ENOG4105D1A	Methyltransferase
C5F13_16580	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C5F13_16585	ENOG4105E9H	Lytic Murein transglycosylase
C5F13_16590	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C5F13_16605	ENOG4108Q2J	Inner membrane protein YebE
C5F13_16625	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C5F13_16640	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C5F13_16645	ENOG4105CX6	glutaminyL-tRNA synthetase
C5F13_16650	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
C5F13_16655	ENOG4107QMS	site-determining protein
C5F13_16660	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
C5F13_16705	ENOG4108SHN	Glycosyl transferase, family 2
C5F13_16720	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C5F13_16750	ENOG4105CEY	Amp-dependent synthetase and ligase
C5F13_16755	ENOG4105FDP	GntR family transcriptional regulator
C5F13_16760	ENOG4105CUZ	uba thif-type nad fad binding protein
C5F13_16775	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C5F13_16795	ENOG4107RSM	transcriptional regulator
C5F13_16820	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C5F13_16825	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C5F13_16830	ENOG4105DDQ	anthranilate synthase
C5F13_16840	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C5F13_16850	ENOG4105NWN	ApaG protein
C5F13_16855	ENOG4105CA3	membrane-bound lytic murein transglycosylase
C5F13_16860	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C5F13_16865	ENOG4105T95	Thiol disulfide interChange protein
C5F13_16880	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C5F13_16890	ENOG4108JU3	Alkyl hydroperoxide reductase
C5F13_16895	ENOG4105C0H	protease
C5F13_16900	ENOG4105E39	Enoyl-CoA hydratase
C5F13_16925	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
C5F13_16930	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C5F13_16935	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C5F13_16940	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C5F13_16945	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C5F13_16950	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C5F13_16955	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C5F13_16960	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C5F13_16970	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C5F13_16975	ENOG4105C25	Primosomal protein n'
C5F13_16980	ENOG4105C4R	Atp-dependent dna helicase
C5F13_16990	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C5F13_17000	ENOG4108JQ6	ABC transporter
C5F13_17005	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C5F13_17010	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C5F13_17030	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C5F13_17035	ENOG41060WC	Enoyl-CoA hydratase
C5F13_17040	ENOG4105E39	Enoyl-CoA hydratase
C5F13_17100	ENOG4105E3B	Multicopper oxidase
C5F13_17110	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C5F13_17120	ENOG41069M3	Transcriptional regulator
C5F13_17125	ENOG4108T2C	cysteine dioxygenase type I
C5F13_17130	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_17160	ENOG4105DZQ	phospholipase D Transphosphatidylase
C5F13_17165	ENOG4105X23	Endonuclease Exonuclease phosphatase
C5F13_17170	ENOG4105C9M	aspartyl-trna synthetase
C5F13_17205	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
C5F13_17210	ENOG4105C2X	Arabinose 5-phosphate isomerase
C5F13_17230	ENOG4108IUZ	ABC transporter
C5F13_17240	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
C5F13_17245	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C5F13_17250	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
C5F13_17265	ENOG4105K6T	rare lipoprotein A
C5F13_17295	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
C5F13_17305	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
C5F13_17315	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C5F13_17320	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C5F13_17325	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C5F13_17365	ENOG4105CD5	CoA-binding domain protein
C5F13_17375	ENOG4105CSU	acyl-Coa dehydrogenase
C5F13_17385	ENOG4105CHU	acetyl-coa acetyltransferase
C5F13_17395	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C5F13_17420	ENOG4105CD5	CoA-binding domain protein
C5F13_17430	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
C5F13_17440	ENOG4105KME	endoribonuclease L-psp
C5F13_17450	ENOG4105CWC	Acetylornithine deacetylase
C5F13_17460	ENOG4105CC9	acyl-Coa dehydrogenase
C5F13_17465	ENOG4105C1G	acyl-Coa dehydrogenase
C5F13_17470	ENOG4105CXG	d-lactate dehydrogenase
C5F13_17505	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C5F13_17525	ENOG4105C1G	acyl-Coa dehydrogenase
C5F13_17545	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C5F13_17550	ENOG4108UKI	Enoyl-CoA hydratase
C5F13_17555	ENOG4105C1G	acyl-Coa dehydrogenase
C5F13_17575	ENOG4107RUY	(E1 component), alpha subunit
C5F13_17580	ENOG4105CPP	Dehydrogenase, E1 component
C5F13_17585	ENOG4105E39	Enoyl-CoA hydratase
C5F13_17590	ENOG4105C7S	Dehydrogenase
C5F13_17610	ENOG41083Z3	extracellular ligand-binding receptor
C5F13_17615	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_17620	ENOG4105C0Z	ABC transporter
C5F13_17625	ENOG4108IV0	ABC, transporter
C5F13_17630	ENOG4107QN2	dihydrolipoyl dehydrogenase
C5F13_17675	ENOG4105D06	uba thif-type nad fad binding protein
C5F13_17680	ENOG4105CN1	protease
C5F13_17685	ENOG41063SB	peptidase
C5F13_17690	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C5F13_17695	ENOG4105C72	UPF0176 protein
C5F13_17700	ENOG4105VW4	glutaredoxin 3
C5F13_17705	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
C5F13_17710	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C5F13_17730	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C5F13_17735	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
C5F13_17740	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C5F13_17750	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C5F13_17780	ENOG4105CH5	extracellular solute-binding protein, family 7
C5F13_17805	ENOG4108UAU	isochorismatase
C5F13_17820	ENOG4105RE0	Asp Glu hydantoin racemase
C5F13_17845	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C5F13_17850	ENOG4105C1A	potassium transporter peripheral membrane
C5F13_17855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C5F13_17860	ENOG4105ES5	Histidine kinase
C5F13_17870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C5F13_17915	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
C5F13_17935	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C5F13_17940	ENOG4107QXX	ABC transporter
C5F13_17950	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C5F13_17955	ENOG4105C79	DNA protecting protein DprA
C5F13_17960	ENOG4105F7P	transcriptional regulator AsnC family
C5F13_17970	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C5F13_17985	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C5F13_17995	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
C5F13_18005	ENOG4108URH	decarboxylase
C5F13_18020	ENOG41084KP	4-oxalocrotonate tautomerase
C5F13_18025	ENOG4105CJP	fad dependent oxidoreductase
C5F13_18050	ENOG4105C8Y	Acetylornithine aminotransferase
C5F13_18075	ENOG4108VUG	Enoyl-CoA hydratase
C5F13_18080	ENOG4107258	Transcriptional regulator
C5F13_18085	ENOG4105CEY	Amp-dependent synthetase and ligase
C5F13_18140	ENOG4105EPW	hflc protein
C5F13_18150	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
C5F13_18200	ENOG4108PNI	recT protein
C5F13_18255	ENOG4105EXG	Transcriptional regulator
C5F13_18270	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C5F13_18275	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C5F13_18280	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C5F13_18285	ENOG4105VG0	50S ribosomal protein l34
C5F13_18295	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C5F13_18300	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C5F13_18305	ENOG4108FUF	Transcriptional regulator, IclR family
C5F13_18310	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C5F13_18325	ENOG4105DMF	Dehydrogenase
C5F13_18375	ENOG4105CHU	acetyl-coa acetyltransferase
C5F13_18380	ENOG4107QX3	carboxylase
C5F13_18395	ENOG4105C8Y	Acetylornithine aminotransferase
C5F13_18420	ENOG4105X58	receptor
C5F13_18425	ENOG4108RPN	Protein smg homolog
C5F13_18440	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C5F13_18455	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
C5F13_18460	ENOG4105CHR	reductase
C5F13_18465	ENOG4105C26	Dehydrogenase
C5F13_18475	ENOG4105C7K	acetolactate synthase
C5F13_18480	ENOG4108YXU	transcriptional regulator AsnC family
C5F13_18485	ENOG4105FFC	UPF0187 protein
C5F13_18495	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C5F13_18510	ENOG4105C3R	Methionine synthase
C5F13_18515	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C5F13_18520	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
C5F13_18525	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C5F13_18530	ENOG4105DWF	phosphomethylpyrimidine kinase
C5F13_18535	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C5F13_18545	ENOG4105DFG	type I secretion outer membrane protein
C5F13_18550	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C5F13_18560	ENOG4105IPI	Membrane
C5F13_18570	ENOG4107SVH	Potassium channel protein
C5F13_18585	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C5F13_18590	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C5F13_18595	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C5F13_18600	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C5F13_18605	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C5F13_18610	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C5F13_18615	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C5F13_18620	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C5F13_18625	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C5F13_18630	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C5F13_18635	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C5F13_18640	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C5F13_18645	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C5F13_18650	ENOG41084PQ	50s ribosomal protein l29
C5F13_18655	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C5F13_18675	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C5F13_18680	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C5F13_18685	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C5F13_18690	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C5F13_18695	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C5F13_18700	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C5F13_18705	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C5F13_18710	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C5F13_18715	ENOG4105VPB	50S ribosomal protein L30
C5F13_18720	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C5F13_18725	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C5F13_18730	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C5F13_18740	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C5F13_18745	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C5F13_18750	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C5F13_18755	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C5F13_18760	ENOG4108ZT0	50S ribosomal protein l17
C5F13_18765	ENOG4107YU2	histidine triad (hIT) protein
C5F13_18770	ENOG4105VF7	tolerance protein
C5F13_18775	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C5F13_18785	ENOG4105D52	delta-aminolevulinic acid dehydratase
C5F13_18790	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C5F13_18795	ENOG4106RE7	Cytochrome
C5F13_18800	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
C5F13_18805	ENOG4105CRE	cytochrome C
C5F13_18810	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C5F13_18820	ENOG4105XQ6	frataxin-like protein
C5F13_18825	ENOG4108JQC	penicillin-binding protein 1A
C5F13_18835	ENOG4105D49	3-dehydroquinate synthase
C5F13_18840	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C5F13_18850	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C5F13_18855	ENOG4107RDB	Major Facilitator
C5F13_18860	ENOG4108UUM	single-stranded DNA-binding protein
C5F13_18900	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C5F13_18905	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C5F13_18910	ENOG4105JNK	Glycosyl transferase (Group 1
C5F13_18930	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C5F13_18955	ENOG4107QP3	malate synthase g
C5F13_18980	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C5F13_18985	ENOG4108ZGC	gaf domain protein
C5F13_18990	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C5F13_19005	ENOG4109066	lysm domain bon superfamily protein
C5F13_19010	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C5F13_19020	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C5F13_19035	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C5F13_19080	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C5F13_19095	ENOG4105E39	Enoyl-CoA hydratase
C5F13_19110	ENOG410846T	CoA-transferase family III
C5F13_19115	ENOG4108IG5	Transcriptional regulator
C5F13_19120	ENOG4105E09	nadh pyrophosphatase
C5F13_19155	ENOG4108IV0	ABC, transporter
C5F13_19165	ENOG4105C32	Amino acid ABC transporter (Permease)
C5F13_19190	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C5F13_19205	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C5F13_19210	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C5F13_19215	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C5F13_19240	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C5F13_19265	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
C5F13_19280	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C5F13_19285	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C5F13_19300	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
C5F13_19305	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C5F13_19315	ENOG4105C4W	S-formylglutathione hydrolase
C5F13_19320	ENOG4107QPD	alcohol dehydrogenase
C5F13_19340	ENOG4105EIF	outer membrane protein W
C5F13_19350	ENOG4105DHJ	ABC, transporter
C5F13_19355	ENOG4105CY3	ABC transporter, permease
C5F13_19360	ENOG4107PE3	Mammalian cell entry related domain protein
C5F13_19380	ENOG4105E3A	(ABC) transporter
C5F13_19390	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C5F13_19395	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C5F13_19400	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C5F13_19405	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C5F13_19410	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C5F13_19415	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C5F13_19420	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C5F13_19425	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C5F13_19430	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C5F13_19440	ENOG4107YU2	histidine triad (hIT) protein
C5F13_19445	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C5F13_19450	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C5F13_19470	ENOG4106DF6	pertussis toxin subunit 1
C5F13_19505	ENOG4105EJX	conjugal transfer ATPase
C5F13_19525	ENOG4108PCE	TRANSFER protein
C5F13_19530	ENOG4105CMA	conjugation trbi family protein
C5F13_19545	ENOG4108Q5Y	Membrane
C5F13_19565	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C5F13_19570	ENOG4105DEF	Extracellular solute-binding protein, family 5
C5F13_19575	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C5F13_19580	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C5F13_19595	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C5F13_19630	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C5F13_19635	ENOG4105BZS	acriflavin resistance protein
C5F13_19650	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
C5F13_19655	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C5F13_19660	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
C5F13_19675	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C5F13_19680	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C5F13_19690	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C5F13_19695	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C5F13_19710	ENOG4105CDA	abc transporter atp-binding protein
C5F13_19715	ENOG4105DRP	amino acid AbC transporter
C5F13_19720	ENOG4105EZ7	amino acid ABC transporter
C5F13_19725	ENOG4107QXX	ABC transporter
C5F13_19730	ENOG4105CAK	Cell division ATP-binding protein ftsE
C5F13_19735	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
C5F13_19740	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
C5F13_19750	ENOG4105CEN	a g-specific adenine glycosylase
C5F13_19760	ENOG4105F2W	methyltransferase
C5F13_19770	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_19775	ENOG410846T	CoA-transferase family III
C5F13_19790	ENOG4105E39	Enoyl-CoA hydratase
C5F13_19805	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C5F13_19810	ENOG4105E39	Enoyl-CoA hydratase
C5F13_19815	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C5F13_19830	ENOG4105CH6	catalase
C5F13_19835	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C5F13_19850	ENOG4105E2B	Taurine dioxygenase
C5F13_19855	ENOG4105CH2	amidohydrolase
C5F13_19860	ENOG4108JQ7	(ABC) transporter
C5F13_19865	ENOG4105C3U	ABC transporter
C5F13_19875	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C5F13_19880	ENOG4105DEF	Extracellular solute-binding protein, family 5
C5F13_19885	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C5F13_19900	ENOG41062D9	Histidine kinase
C5F13_19920	ENOG4105CHM	Aminotransferase