locus-tag	class	description
C5F13_00005	COG0445	tRNA wobble uridine modification
C5F13_00015	COG1192	Involved in chromosome partitioning
C5F13_00025	COG1475	DNA binding
C5F13_00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5F13_00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5F13_00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C5F13_00075	COG0081	regulation of translation
C5F13_00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C5F13_00085	COG0222	ribosome binding
C5F13_00090	COG0085	RNA polymerase activity
C5F13_00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C5F13_00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_00160	COG1024	Enoyl-CoA hydratase
C5F13_00180	COG0752	glycyl-tRNA synthetase alpha subunit
C5F13_00185	COG0751	glycine-tRNA ligase activity
C5F13_00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C5F13_00195	COG0204	Acyl-transferase
C5F13_00210	COG0242	peptide deformylase activity
C5F13_00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C5F13_00255	COG2813	Specifically methylates the guanine in position
C5F13_00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C5F13_00270	COG2223	nitrite transmembrane transporter activity
C5F13_00280	COG1794	racemase activity, acting on amino acids and derivatives
C5F13_00285	COG1126	abc transporter atp-binding protein
C5F13_00290	COG0765	amino acid transport
C5F13_00295	COG0765	amino acid transport
C5F13_00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C5F13_00395	COG0326	Molecular chaperone. Has ATPase activity
C5F13_00400	COG0625	glutathione transferase activity
C5F13_00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5F13_00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5F13_00450	COG0438	transferase activity, transferring glycosyl groups
C5F13_00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C5F13_00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5F13_00490	COG0859	PFAM glycosyl transferase family 9
C5F13_00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C5F13_00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C5F13_00520	COG1127	ABC transporter
C5F13_00540	COG1686	Belongs to the peptidase S11 family
C5F13_00550	COG2921	Belongs to the UPF0250 family
C5F13_00555	COG0321	lipoyl(octanoyl) transferase activity
C5F13_00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C5F13_00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5F13_00605	COG0018	arginyl-trna synthetase
C5F13_00625	COG0395	ABC-type sugar transport system, permease component
C5F13_00630	COG1175	transmembrane transport
C5F13_00635	COG1653	transport
C5F13_00640	COG3842	ATPase activity
C5F13_00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C5F13_00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C5F13_00675	COG1609	Transcriptional regulator
C5F13_00685	COG0154	amidase activity
C5F13_00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5F13_00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C5F13_00710	COG0583	DNA-binding transcription factor activity
C5F13_00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C5F13_00745	COG1802	Transcriptional regulator
C5F13_00760	COG1024	Enoyl-CoA hydratase
C5F13_00775	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_00790	COG1984	allophanate hydrolase subunit 2
C5F13_00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C5F13_00805	COG0583	DNA-binding transcription factor activity
C5F13_00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5F13_00820	COG5002	protein histidine kinase activity
C5F13_00830	COG5002	protein histidine kinase activity
C5F13_00835	COG0745	RESPONSE REGULATOR receiver
C5F13_00840	COG2226	methyltransferase
C5F13_00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C5F13_00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C5F13_00885	COG0513	Belongs to the DEAD box helicase family
C5F13_00890	COG1280	lysine exporter protein (LysE YggA)
C5F13_00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C5F13_00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5F13_00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5F13_00945	COG0489	protein tyrosine kinase activity
C5F13_00960	COG0717	Belongs to the dCTP deaminase family
C5F13_00985	COG1982	Orn Lys Arg decarboxylase major
C5F13_00990	COG2081	HI0933 family
C5F13_01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5F13_01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C5F13_01015	COG0509	glycine decarboxylation via glycine cleavage system
C5F13_01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5F13_01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5F13_01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C5F13_01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5F13_01085	COG1414	Transcriptional regulator
C5F13_01090	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_01095	COG2031	fatty acid transporter
C5F13_01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5F13_01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C5F13_01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C5F13_01125	COG4257	antibiotic catabolic process
C5F13_01150	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C5F13_01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5F13_01185	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5F13_01205	COG2188	Transcriptional regulator
C5F13_01210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C5F13_01235	COG0617	tRNA 3'-terminal CCA addition
C5F13_01250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C5F13_01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C5F13_01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C5F13_01265	COG0586	Pfam SNARE associated Golgi protein
C5F13_01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5F13_01275	COG0802	atpase or kinase
C5F13_01280	COG0114	fumarate hydratase activity
C5F13_01290	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_01300	COG0405	Gamma-glutamyltransferase
C5F13_01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_01340	COG1294	oxidase, subunit
C5F13_01350	COG4988	ABC transporter
C5F13_01355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C5F13_01360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5F13_01410	COG2969	positive regulation of protein catabolic process
C5F13_01415	COG0625	glutathione transferase activity
C5F13_01420	COG2857	Cytochrome c1
C5F13_01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C5F13_01430	COG0723	plastoquinol--plastocyanin reductase activity
C5F13_01435	COG1970	mechanosensitive ion channel activity
C5F13_01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C5F13_01455	COG2808	Putative FMN-binding domain
C5F13_01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5F13_01465	COG0747	negative chemotaxis
C5F13_01470	COG0657	acetylesterase activity
C5F13_01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5F13_01485	COG2207	Transcriptional regulator
C5F13_01490	COG0129	dihydroxy-acid dehydratase activity
C5F13_01495	COG2814	Major facilitator Superfamily
C5F13_01500	COG0583	DNA-binding transcription factor activity
C5F13_01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
C5F13_01550	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_01560	COG0411	ABC transporter
C5F13_01565	COG0410	ABC transporter
C5F13_01580	COG1024	Enoyl-CoA hydratase
C5F13_01585	COG1960	acyl-CoA dehydrogenase activity
C5F13_01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C5F13_01630	COG1678	Uncharacterized ACR, COG1678
C5F13_01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C5F13_01640	COG0540	Belongs to the ATCase OTCase family
C5F13_01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C5F13_01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5F13_01700	COG1234	tRNA 3'-trailer cleavage
C5F13_01720	COG3064	Membrane
C5F13_01735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5F13_01750	COG1683	Conserved Protein
C5F13_01755	COG1120	ATPase activity
C5F13_01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5F13_01765	COG4558	Periplasmic binding protein
C5F13_01770	COG3720	iron ion transport
C5F13_01780	COG3712	iron ion homeostasis
C5F13_01785	COG1595	DNA-templated transcription, initiation
C5F13_01820	COG1802	Transcriptional regulator
C5F13_01830	COG3069	C4-dicarboxylate transmembrane transporter activity
C5F13_01840	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_01875	COG2860	membrane
C5F13_01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5F13_01885	COG0708	Exodeoxyribonuclease III
C5F13_01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C5F13_01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5F13_01900	COG0154	amidase activity
C5F13_01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5F13_01910	COG1077	Cell shape determining protein MreB Mrl
C5F13_01915	COG1792	Involved in formation and maintenance of cell shape
C5F13_01925	COG0768	penicillin binding
C5F13_01930	COG0772	Belongs to the SEDS family
C5F13_01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C5F13_01940	COG0471	metal ion transport
C5F13_01945	COG1309	transcriptional regulator
C5F13_01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C5F13_01970	COG2823	Periplasmic or secreted lipoprotein
C5F13_01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C5F13_01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5F13_02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_02040	COG0492	ferredoxin-NADP+ reductase activity
C5F13_02050	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_02055	COG1024	Enoyl-CoA hydratase
C5F13_02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5F13_02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_02065	COG0028	Belongs to the TPP enzyme family
C5F13_02090	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_02105	COG0697	spore germination
C5F13_02135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C5F13_02140	COG0463	Glycosyl transferase, family 2
C5F13_02155	COG0786	glutamate:sodium symporter activity
C5F13_02165	COG2031	fatty acid transporter
C5F13_02180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5F13_02195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5F13_02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5F13_02220	COG1285	pathogenesis
C5F13_02225	COG1253	flavin adenine dinucleotide binding
C5F13_02230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_02235	COG1024	Enoyl-CoA hydratase
C5F13_02240	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_02245	COG0583	DNA-binding transcription factor activity
C5F13_02250	COG1960	acyl-CoA dehydrogenase activity
C5F13_02260	COG0183	Belongs to the thiolase family
C5F13_02280	COG0583	DNA-binding transcription factor activity
C5F13_02285	COG1278	Cold shock
C5F13_02295	COG1802	Transcriptional regulator
C5F13_02300	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_02305	COG2031	fatty acid transporter
C5F13_02310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5F13_02310	COG1017	nitric oxide dioxygenase activity
C5F13_02315	COG0251	oxidation-reduction process
C5F13_02335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_02345	COG0583	DNA-binding transcription factor activity
C5F13_02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_02360	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C5F13_02365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C5F13_02370	COG0546	phosphoglycolate phosphatase activity
C5F13_02380	COG1530	ribonuclease E activity
C5F13_02405	COG0159	tryptophan synthase activity
C5F13_02410	COG0133	tryptophan synthase activity
C5F13_02420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5F13_02425	COG3228	Belongs to the MtfA family
C5F13_02435	COG0251	oxidation-reduction process
C5F13_02440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C5F13_02445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C5F13_02460	COG2878	Part of a membrane complex involved in electron transport
C5F13_02465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C5F13_02470	COG0411	ABC transporter
C5F13_02485	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_02500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5F13_02505	COG0411	ABC transporter
C5F13_02520	COG1268	BioY protein
C5F13_02525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C5F13_02530	COG1122	ATPase activity
C5F13_02535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5F13_02555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C5F13_02565	COG1196	nuclear chromosome segregation
C5F13_02570	COG0477	Major facilitator Superfamily
C5F13_02575	COG1573	uracil-dna glycosylase
C5F13_02580	COG1214	PFAM Peptidase M22, glycoprotease
C5F13_02585	COG0745	RESPONSE REGULATOR receiver
C5F13_02595	COG2205	protein histidine kinase activity
C5F13_02600	COG0450	alkyl hydroperoxide reductase
C5F13_02605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5F13_02625	COG2186	Transcriptional regulator
C5F13_02645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5F13_02655	COG0583	DNA-binding transcription factor activity
C5F13_02665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5F13_02670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C5F13_02675	COG0137	argininosuccinate synthase activity
C5F13_02680	COG3158	transport of potassium into the cell
C5F13_02685	COG0642	Histidine kinase
C5F13_02690	COG0745	RESPONSE REGULATOR receiver
C5F13_02715	COG0776	regulation of translation
C5F13_02720	COG3128	pkhd-type hydroxylase
C5F13_02730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5F13_02735	COG0557	exoribonuclease II activity
C5F13_02755	COG2153	protein acetylation
C5F13_02760	COG0679	Auxin Efflux Carrier
C5F13_02765	COG2391	methyltransferase activity
C5F13_02770	COG0069	glutamate synthase activity
C5F13_02780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5F13_02790	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C5F13_02830	COG3706	GGDEF domain
C5F13_02855	COG0583	DNA-binding transcription factor activity
C5F13_02865	COG1053	succinate dehydrogenase
C5F13_02885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C5F13_02890	COG0459	protein refolding
C5F13_02895	COG3468	outer membrane autotransporter barrel domain protein
C5F13_02910	COG1252	NADH dehydrogenase
C5F13_02915	COG0284	orotidine-5'-phosphate decarboxylase activity
C5F13_02920	COG1546	Belongs to the CinA family
C5F13_02920	COG1058	Belongs to the CinA family
C5F13_02925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C5F13_02935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5F13_02940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C5F13_02980	COG3639	organic phosphonate transmembrane transporter activity
C5F13_02985	COG3639	organic phosphonate transmembrane transporter activity
C5F13_03005	COG0742	ribosomal rna small subunit methyltransferase
C5F13_03010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C5F13_03015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5F13_03020	COG3135	benzoate transporter
C5F13_03035	COG0640	Transcriptional regulator
C5F13_03065	COG4172	Belongs to the ABC transporter superfamily
C5F13_03070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_03075	COG0601	transmembrane transport
C5F13_03085	COG0281	malic enzyme
C5F13_03085	COG0280	phosphate acetyltransferase
C5F13_03145	COG0583	DNA-binding transcription factor activity
C5F13_03160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C5F13_03165	COG0167	dihydroorotate dehydrogenase activity
C5F13_03185	COG1414	Transcriptional regulator
C5F13_03190	COG1546	Belongs to the CinA family
C5F13_03190	COG1058	Belongs to the CinA family
C5F13_03210	COG0513	Belongs to the DEAD box helicase family
C5F13_03240	COG0429	hydrolase of the alpha beta-hydrolase fold
C5F13_03245	COG4783	chaperone-mediated protein folding
C5F13_03260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C5F13_03285	COG0006	proline dipeptidase activity
C5F13_03295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5F13_03315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C5F13_03320	COG0632	four-way junction helicase activity
C5F13_03335	COG2255	four-way junction helicase activity
C5F13_03340	COG0514	ATP-dependent DNA helicase (RecQ)
C5F13_03355	COG0288	reversible hydration of carbon dioxide
C5F13_03360	COG0154	amidase activity
C5F13_03365	COG0683	leucine binding
C5F13_03370	COG4211	Belongs to the binding-protein-dependent transport system permease family
C5F13_03385	COG0410	ABC transporter
C5F13_03400	COG1464	Belongs to the NlpA lipoprotein family
C5F13_03540	COG1196	nuclear chromosome segregation
C5F13_03610	COG2135	peptidase activity
C5F13_03625	COG0494	nUDIX hydrolase
C5F13_03630	COG0442	prolyl-tRNA aminoacylation
C5F13_03635	COG0824	Thioesterase
C5F13_03640	COG0811	peptide transport
C5F13_03645	COG0848	biopolymer transport protein
C5F13_03655	COG0823	Involved in the tonB-independent uptake of proteins
C5F13_03670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5F13_03675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C5F13_03710	COG0700	Nucleoside recognition
C5F13_03715	COG0469	pyruvate kinase activity
C5F13_03720	COG1929	Belongs to the glycerate kinase type-1 family
C5F13_03725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C5F13_03730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5F13_03735	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C5F13_03745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C5F13_03755	COG2154	pterin-4-alpha-carbinolamine dehydratase
C5F13_03780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5F13_03785	COG0154	amidase activity
C5F13_03795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_03800	COG0601	transmembrane transport
C5F13_03805	COG0747	negative chemotaxis
C5F13_03825	COG0019	diaminopimelate decarboxylase activity
C5F13_03840	COG2353	YceI-like domain
C5F13_03845	COG4774	siderophore transport
C5F13_03850	COG3712	iron ion homeostasis
C5F13_03890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C5F13_03895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C5F13_03900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C5F13_03905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C5F13_03915	COG0142	geranyltranstransferase activity
C5F13_03925	COG0583	DNA-binding transcription factor activity
C5F13_03935	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
C5F13_03940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_03955	COG2994	toxin metabolic process
C5F13_03965	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
C5F13_03970	COG2274	protein secretion by the type I secretion system
C5F13_03975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5F13_03980	COG1538	Outer membrane efflux protein
C5F13_04000	COG0765	amino acid transport
C5F13_04005	COG1126	abc transporter atp-binding protein
C5F13_04025	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_04035	COG1802	Transcriptional regulator
C5F13_04045	COG1802	Transcriptional regulator
C5F13_04055	COG0318	PFAM AMP-dependent synthetase and ligase
C5F13_04065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_04075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5F13_04085	COG0028	Belongs to the TPP enzyme family
C5F13_04105	COG0308	aminopeptidase N
C5F13_04110	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C5F13_04130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C5F13_04135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C5F13_04140	COG0560	Phosphoserine phosphatase
C5F13_04145	COG0583	DNA-binding transcription factor activity
C5F13_04150	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_04155	COG0028	Belongs to the TPP enzyme family
C5F13_04170	COG4774	siderophore transport
C5F13_04175	COG4774	siderophore transport
C5F13_04185	COG1007	ATP synthesis coupled electron transport
C5F13_04200	COG0713	ATP synthesis coupled electron transport
C5F13_04210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5F13_04215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C5F13_04220	COG1034	ATP synthesis coupled electron transport
C5F13_04230	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C5F13_04235	COG0649	NAD binding
C5F13_04240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5F13_04245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5F13_04250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5F13_04255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C5F13_04285	COG0671	phosphoesterase, PA-phosphatase related
C5F13_04295	COG1597	lipid kinase activity
C5F13_04300	COG0583	DNA-binding transcription factor activity
C5F13_04305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5F13_04315	COG1733	regulation of RNA biosynthetic process
C5F13_04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5F13_04325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5F13_04340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C5F13_04360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_04380	COG3608	succinylglutamate desuccinylase aspartoacylase
C5F13_04385	COG0626	cystathionine gamma-synthase activity
C5F13_04390	COG0583	DNA-binding transcription factor activity
C5F13_04425	COG3799	methylaspartate ammonia-lyase activity
C5F13_04435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5F13_04445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5F13_04450	COG0149	triose-phosphate isomerase activity
C5F13_04470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C5F13_04490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C5F13_04505	COG1183	phosphatidylcholine synthase activity
C5F13_04510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C5F13_04515	COG0440	acetolactate synthase activity
C5F13_04520	COG0028	Belongs to the TPP enzyme family
C5F13_04535	COG5265	(ABC) transporter
C5F13_04540	COG0500	methyltransferase
C5F13_04560	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C5F13_04580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C5F13_04590	COG0511	ligase activity, forming carbon-carbon bonds
C5F13_04615	COG2188	Transcriptional regulator
C5F13_04620	COG0439	Biotin carboxylase
C5F13_04670	COG5265	(ABC) transporter
C5F13_04680	COG0667	Aldo Keto reductase
C5F13_04695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C5F13_04735	COG0583	DNA-binding transcription factor activity
C5F13_04765	COG2814	Major facilitator Superfamily
C5F13_04775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5F13_04790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C5F13_04800	COG0287	Prephenate dehydrogenase
C5F13_04805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C5F13_04810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C5F13_04830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C5F13_04835	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C5F13_04840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5F13_04845	COG1596	polysaccharide export
C5F13_04845	COG1555	photosystem II stabilization
C5F13_04860	COG2951	lytic endotransglycosylase activity
C5F13_04865	COG0123	including yeast histone deacetylase and acetoin utilization protein
C5F13_04880	COG1960	acyl-CoA dehydrogenase activity
C5F13_04885	COG0450	alkyl hydroperoxide reductase
C5F13_04905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C5F13_04940	COG0335	large ribosomal subunit rRNA binding
C5F13_04955	COG0667	Aldo Keto reductase
C5F13_04970	COG3161	chorismate lyase activity
C5F13_04975	COG1187	pseudouridine synthase activity
C5F13_04995	COG1538	Outer membrane efflux protein
C5F13_05005	COG1999	signal sequence binding
C5F13_05010	COG0339	signal peptide processing
C5F13_05020	COG4566	intracellular signal transduction
C5F13_05030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C5F13_05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5F13_05040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5F13_05045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5F13_05055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5F13_05060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C5F13_05065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5F13_05070	COG0126	phosphoglycerate kinase activity
C5F13_05075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5F13_05080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C5F13_05095	COG0625	glutathione transferase activity
C5F13_05125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C5F13_05135	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5F13_05145	COG0739	heme binding
C5F13_05155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C5F13_05165	COG1191	sigma factor activity
C5F13_05195	COG0643	Histidine kinase
C5F13_05195	COG2198	Histidine kinase
C5F13_05200	COG0835	chemotaxis
C5F13_05205	COG0840	transmembrane signaling receptor activity
C5F13_05215	COG2201	protein-glutamate methylesterase activity
C5F13_05220	COG0745	RESPONSE REGULATOR receiver
C5F13_05225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C5F13_05250	COG0667	Aldo Keto reductase
C5F13_05260	COG4535	Mg2 and Co2 transporter CorC
C5F13_05265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C5F13_05270	COG1702	phosphate starvation-inducible protein PhoH
C5F13_05275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5F13_05290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5F13_05295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5F13_05300	COG1862	Preprotein translocase
C5F13_05305	COG0343	queuine tRNA-ribosyltransferase activity
C5F13_05310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C5F13_05315	COG2027	D-alanyl-D-alanine carboxypeptidase
C5F13_05320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C5F13_05350	COG1648	precorrin-2 dehydrogenase activity
C5F13_05350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5F13_05375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C5F13_05380	COG0741	lytic transglycosylase activity
C5F13_05385	COG0436	Aminotransferase
C5F13_05395	COG0281	malic enzyme
C5F13_05395	COG0280	phosphate acetyltransferase
C5F13_05405	COG2732	(Barnase) inhibitor
C5F13_05420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5F13_05445	COG0248	Ppx GppA phosphatase
C5F13_05455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5F13_05465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5F13_05470	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C5F13_05475	COG1534	Rna-binding protein
C5F13_05505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5F13_05520	COG1295	ribonuclease BN
C5F13_05530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C5F13_05535	COG0745	RESPONSE REGULATOR receiver
C5F13_05540	COG2205	protein histidine kinase activity
C5F13_05575	COG1022	Amp-dependent synthetase and ligase
C5F13_05590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C5F13_05595	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_05605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C5F13_05620	COG1136	(ABC) transporter
C5F13_05625	COG0084	hydrolase, TatD family'
C5F13_05650	COG2333	competence protein COMEC
C5F13_05650	COG0658	competence protein
C5F13_05660	COG0613	PHP domain protein
C5F13_05680	COG3539	Fimbrial protein
C5F13_05685	COG0281	malic enzyme
C5F13_05685	COG0280	phosphate acetyltransferase
C5F13_05695	COG1522	sequence-specific DNA binding
C5F13_05705	COG0567	Dehydrogenase, E1 component
C5F13_05710	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5F13_05715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5F13_05720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C5F13_05725	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_05730	COG0583	DNA-binding transcription factor activity
C5F13_05740	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_05765	COG0180	Tryptophanyl-tRNA synthetase
C5F13_05770	COG2183	response to ionizing radiation
C5F13_05775	COG1199	ATP-dependent helicase activity
C5F13_05785	COG0564	pseudouridine synthase activity
C5F13_05795	COG3243	poly(R)-hydroxyalkanoic acid synthase
C5F13_05800	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_05805	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
C5F13_05860	COG0583	DNA-binding transcription factor activity
C5F13_05870	COG2814	Major facilitator Superfamily
C5F13_05885	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5F13_05900	COG2084	Dehydrogenase
C5F13_05905	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_05930	COG2988	succinylglutamate desuccinylase activity
C5F13_05955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C5F13_05960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C5F13_05965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C5F13_05970	COG0047	phosphoribosylformylglycinamidine synthase activity
C5F13_05970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C5F13_05975	COG3064	Membrane
C5F13_05975	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C5F13_05975	COG3210	domain, Protein
C5F13_06005	COG0235	Class ii aldolase
C5F13_06010	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C5F13_06015	COG0720	synthase
C5F13_06020	COG0602	queuosine metabolic process
C5F13_06045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5F13_06075	COG1053	succinate dehydrogenase
C5F13_06080	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_06105	COG3842	ATPase activity
C5F13_06115	COG0395	ABC-type sugar transport system, permease component
C5F13_06145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_06150	COG0420	3'-5' exonuclease activity
C5F13_06195	COG0519	Catalyzes the synthesis of GMP from XMP
C5F13_06195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5F13_06210	COG3550	peptidyl-serine autophosphorylation
C5F13_06220	COG0477	Major facilitator Superfamily
C5F13_06235	COG1228	amidohydrolase
C5F13_06245	COG1116	anion transmembrane transporter activity
C5F13_06250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_06285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C5F13_06305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C5F13_06335	COG2814	Major facilitator Superfamily
C5F13_06350	COG1280	lysine exporter protein (LysE YggA)
C5F13_06370	COG0747	negative chemotaxis
C5F13_06375	COG0601	transmembrane transport
C5F13_06385	COG4172	Belongs to the ABC transporter superfamily
C5F13_06390	COG1609	Transcriptional regulator
C5F13_06420	COG0586	Pfam SNARE associated Golgi protein
C5F13_06435	COG0500	methyltransferase
C5F13_06450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5F13_06460	COG0756	dUTP diphosphatase activity
C5F13_06475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C5F13_06480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C5F13_06485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C5F13_06490	COG0072	phenylalanine-tRNA ligase activity
C5F13_06490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5F13_06495	COG0776	regulation of translation
C5F13_06560	COG0540	Belongs to the ATCase OTCase family
C5F13_06565	COG2974	May be involved in recombination
C5F13_06575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_06580	COG0583	DNA-binding transcription factor activity
C5F13_06600	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_06615	COG3842	ATPase activity
C5F13_06620	COG1024	Enoyl-CoA hydratase
C5F13_06620	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5F13_06630	COG0642	Histidine kinase
C5F13_06640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C5F13_06645	COG2137	regulation of response to DNA damage stimulus
C5F13_06650	COG0583	DNA-binding transcription factor activity
C5F13_06655	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C5F13_06665	COG0045	succinate-CoA ligase (ADP-forming) activity
C5F13_06670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C5F13_06675	COG0861	Integral membrane protein TerC family
C5F13_06680	COG0861	Integral membrane protein TerC family
C5F13_06685	COG0181	hydroxymethylbilane synthase activity
C5F13_06705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C5F13_06745	COG4964	Belongs to the GSP D family
C5F13_06770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C5F13_06780	COG0583	DNA-binding transcription factor activity
C5F13_06790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_06795	COG4311	Sarcosine oxidase, delta subunit
C5F13_06800	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5F13_06800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C5F13_06835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C5F13_06840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C5F13_06845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5F13_06850	COG0735	belongs to the Fur family
C5F13_06855	COG0497	DNA recombination
C5F13_06860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5F13_06865	COG1420	regulation of RNA biosynthetic process
C5F13_06870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C5F13_06880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5F13_06890	COG0443	Heat shock 70 kDa protein
C5F13_06900	COG0612	Peptidase, M16
C5F13_06920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5F13_06965	COG0745	RESPONSE REGULATOR receiver
C5F13_06975	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C5F13_06980	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C5F13_06985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C5F13_07000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5F13_07020	COG1193	negative regulation of DNA recombination
C5F13_07025	COG0492	ferredoxin-NADP+ reductase activity
C5F13_07030	COG1674	ftsk spoiiie
C5F13_07035	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5F13_07040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5F13_07045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C5F13_07070	COG3706	GGDEF domain
C5F13_07090	COG2814	Major facilitator Superfamily
C5F13_07135	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_07145	COG3022	response to hydroperoxide
C5F13_07160	COG3023	N-Acetylmuramoyl-L-alanine amidase
C5F13_07170	COG0424	maF-like protein
C5F13_07175	COG1399	metal-binding, possibly nucleic acid-binding protein
C5F13_07180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C5F13_07185	COG0416	fatty acid biosynthetic process
C5F13_07190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5F13_07205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5F13_07210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5F13_07235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5F13_07240	COG0481	GTPase activity
C5F13_07245	COG0681	Belongs to the peptidase S26 family
C5F13_07250	COG0571	ribonuclease III activity
C5F13_07255	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C5F13_07260	COG1381	Involved in DNA repair and RecF pathway recombination
C5F13_07270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5F13_07285	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_07290	COG0670	Belongs to the BI1 family
C5F13_07305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5F13_07315	COG0583	DNA-binding transcription factor activity
C5F13_07330	COG0583	DNA-binding transcription factor activity
C5F13_07345	COG0791	NLP P60 protein
C5F13_07355	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C5F13_07365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5F13_07370	COG0697	spore germination
C5F13_07375	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C5F13_07390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5F13_07420	COG1446	asparaginase
C5F13_07425	COG4172	Belongs to the ABC transporter superfamily
C5F13_07430	COG0747	negative chemotaxis
C5F13_07440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_07465	COG0504	CTP synthase activity
C5F13_07480	COG0148	phosphopyruvate hydratase activity
C5F13_07485	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C5F13_07515	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C5F13_07525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5F13_07580	COG0039	L-malate dehydrogenase activity
C5F13_07585	COG2188	Transcriptional regulator
C5F13_07590	COG2009	succinate dehydrogenase
C5F13_07595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C5F13_07600	COG1053	succinate dehydrogenase
C5F13_07605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C5F13_07610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C5F13_07615	COG0372	Belongs to the citrate synthase family
C5F13_07640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C5F13_07645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C5F13_07655	COG3642	lipopolysaccharide core region biosynthetic process
C5F13_07660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C5F13_07665	COG3842	ATPase activity
C5F13_07670	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5F13_07675	COG1177	transmembrane transport
C5F13_07685	COG2094	Belongs to the DNA glycosylase MPG family
C5F13_07700	COG1960	acyl-CoA dehydrogenase activity
C5F13_07705	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C5F13_07710	COG0704	Plays a role in the regulation of phosphate uptake
C5F13_07720	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C5F13_07725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C5F13_07725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C5F13_07730	COG1643	Atp-dependent helicase
C5F13_07745	COG0438	transferase activity, transferring glycosyl groups
C5F13_07750	COG0726	polysaccharide deacetylase
C5F13_07755	COG0463	Glycosyl transferase, family 2
C5F13_07760	COG0438	transferase activity, transferring glycosyl groups
C5F13_07765	COG2194	sulfuric ester hydrolase activity
C5F13_07790	COG0859	PFAM glycosyl transferase family 9
C5F13_07795	COG1132	(ABC) transporter
C5F13_07810	COG0077	Prephenate dehydratase
C5F13_07815	COG1530	ribonuclease E activity
C5F13_07855	COG3468	outer membrane autotransporter barrel domain protein
C5F13_07860	COG0424	maF-like protein
C5F13_07865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C5F13_07870	COG0799	negative regulation of ribosome biogenesis
C5F13_07875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C5F13_07880	COG0408	coproporphyrinogen oxidase activity
C5F13_07885	COG0151	Belongs to the GarS family
C5F13_07890	COG0217	transcriptional regulatory protein
C5F13_07895	COG0433	COG0433 Predicted ATPase
C5F13_07900	COG1115	amino acid carrier protein
C5F13_07905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5F13_07915	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_07940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C5F13_07955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_07965	COG0747	negative chemotaxis
C5F13_07975	COG0473	3-isopropylmalate dehydrogenase activity
C5F13_07980	COG2814	Major facilitator Superfamily
C5F13_07985	COG1566	PFAM secretion protein HlyD family protein
C5F13_07995	COG1846	Transcriptional regulator
C5F13_08005	COG0697	spore germination
C5F13_08015	COG0501	Belongs to the peptidase M48B family
C5F13_08035	COG0583	DNA-binding transcription factor activity
C5F13_08040	COG3842	ATPase activity
C5F13_08045	COG1178	ABC-type Fe3 transport system permease component
C5F13_08050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5F13_08055	COG1840	ABC-type Fe3 transport system, periplasmic component
C5F13_08080	COG2233	PERMEase
C5F13_08085	COG0840	transmembrane signaling receptor activity
C5F13_08090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5F13_08120	COG4789	Type iii secretion
C5F13_08185	COG4669	(LipO)protein
C5F13_08215	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5F13_08220	COG4790	Type iii secretion
C5F13_08225	COG4794	Type iii secretion
C5F13_08230	COG4791	protein targeting
C5F13_08235	COG4792	protein secretion
C5F13_08250	COG1595	DNA-templated transcription, initiation
C5F13_08270	COG2208	phosphoserine phosphatase activity
C5F13_08270	COG2770	Histidine kinase
C5F13_08280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5F13_08285	COG2172	sigma factor antagonist activity
C5F13_08290	COG1366	Belongs to the anti-sigma-factor antagonist family
C5F13_08295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5F13_08335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5F13_08375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5F13_08385	COG2252	PERMEase
C5F13_08390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C5F13_08400	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C5F13_08405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C5F13_08410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C5F13_08435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5F13_08440	COG0789	Transcriptional regulator
C5F13_08450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C5F13_08450	COG0678	peroxiredoxin activity
C5F13_08460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C5F13_08465	COG0584	glycerophosphoryl diester phosphodiesterase
C5F13_08470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5F13_08480	COG4181	ATPase activity
C5F13_08495	COG2823	Periplasmic or secreted lipoprotein
C5F13_08505	COG3237	CsbD-like
C5F13_08535	COG2833	Protein of unknown function (DUF455)
C5F13_08540	COG2951	lytic endotransglycosylase activity
C5F13_08560	COG1522	sequence-specific DNA binding
C5F13_08570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5F13_08575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C5F13_08580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C5F13_08585	COG0196	riboflavin kinase activity
C5F13_08590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C5F13_08610	COG0210	DNA helicase
C5F13_08615	COG4771	TonB-dependent receptor
C5F13_08620	COG0488	(ABC) transporter
C5F13_08625	COG2890	protein-(glutamine-N5) methyltransferase activity
C5F13_08630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5F13_08635	COG2171	N-acyltransferase activity
C5F13_08670	COG1278	Cold shock
C5F13_08680	COG1278	Cold shock
C5F13_08690	COG0544	peptidyl-prolyl cis-trans isomerase activity
C5F13_08695	COG0740	serine-type endopeptidase activity
C5F13_08700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C5F13_08705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C5F13_08710	COG0583	DNA-binding transcription factor activity
C5F13_08715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_08730	COG1024	Enoyl-CoA hydratase
C5F13_08740	COG0183	Belongs to the thiolase family
C5F13_08745	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_08765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5F13_08785	COG2197	response regulator
C5F13_08800	COG0166	Belongs to the GPI family
C5F13_08805	COG1045	serine acetyltransferase
C5F13_08815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C5F13_08820	COG0483	inositol monophosphate 1-phosphatase activity
C5F13_08825	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_08830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C5F13_08845	COG0210	DNA helicase
C5F13_08850	COG0598	Magnesium transport protein CorA
C5F13_08860	COG0747	negative chemotaxis
C5F13_08865	COG0601	transmembrane transport
C5F13_08870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_08875	COG4172	Belongs to the ABC transporter superfamily
C5F13_08880	COG1846	Transcriptional regulator
C5F13_08935	COG4964	Belongs to the GSP D family
C5F13_08975	COG2204	response regulator
C5F13_08990	COG1595	DNA-templated transcription, initiation
C5F13_09000	COG3474	cytochrome
C5F13_09005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C5F13_09020	COG3384	dioxygenase
C5F13_09025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C5F13_09055	COG2885	chlorophyll binding
C5F13_09090	COG0697	spore germination
C5F13_09095	COG0730	response to heat
C5F13_09115	COG0583	DNA-binding transcription factor activity
C5F13_09120	COG0427	acetyl-CoA hydrolase
C5F13_09175	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5F13_09180	COG0154	amidase activity
C5F13_09190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C5F13_09205	COG0495	leucyl-tRNA aminoacylation
C5F13_09210	COG2814	Major facilitator Superfamily
C5F13_09215	COG1846	Transcriptional regulator
C5F13_09240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5F13_09245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C5F13_09250	COG2814	Major facilitator Superfamily
C5F13_09270	COG4176	ABC-type proline glycine betaine transport system permease component
C5F13_09280	COG1942	4-Oxalocrotonate Tautomerase
C5F13_09285	COG0183	Belongs to the thiolase family
C5F13_09295	COG1802	Transcriptional regulator
C5F13_09305	COG1024	Enoyl-CoA hydratase
C5F13_09320	COG2032	superoxide dismutase activity
C5F13_09335	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C5F13_09360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5F13_09365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5F13_09375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C5F13_09380	COG0736	holo-[acyl-carrier-protein] synthase activity
C5F13_09385	COG1472	Belongs to the glycosyl hydrolase 3 family
C5F13_09390	COG0322	excinuclease ABC activity
C5F13_09395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C5F13_09405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C5F13_09405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C5F13_09410	COG2224	Isocitrate lyase
C5F13_09430	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_09440	COG4638	Rieske (2fe-2S)
C5F13_09445	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C5F13_09450	COG1024	Enoyl-CoA hydratase
C5F13_09460	COG0633	Ferredoxin
C5F13_09465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_09480	COG0183	Belongs to the thiolase family
C5F13_09495	COG0583	DNA-binding transcription factor activity
C5F13_09525	COG2346	COG2346, Truncated hemoglobins
C5F13_09650	COG2207	Transcriptional regulator
C5F13_09700	COG1132	(ABC) transporter
C5F13_09725	COG0659	secondary active sulfate transmembrane transporter activity
C5F13_09755	COG2169	Transcriptional regulator
C5F13_09760	COG5507	3-demethylubiquinone-9 3-methyltransferase
C5F13_09765	COG0384	phenazine biosynthesis protein PhzF
C5F13_09770	COG0583	DNA-binding transcription factor activity
C5F13_09775	COG2733	membrane
C5F13_09790	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_09795	COG3284	Transcriptional regulator
C5F13_09815	COG1380	Effector of murein hydrolase LrgA
C5F13_09820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C5F13_09820	COG4106	trans-aconitate 2-methyltransferase activity
C5F13_09830	COG0156	8-amino-7-oxononanoate synthase activity
C5F13_09900	COG1131	(ABC) transporter
C5F13_09905	COG0842	Transport permease protein
C5F13_09910	COG0628	permease
C5F13_09945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C5F13_09955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C5F13_09965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C5F13_09970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C5F13_09975	COG0330	HflC and HflK could
C5F13_09980	COG0330	HflC and HflK could
C5F13_09985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C5F13_09990	COG1923	regulation of RNA biosynthetic process
C5F13_09995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C5F13_10000	COG1160	GTP binding
C5F13_10005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5F13_10010	COG2976	Protein conserved in bacteria
C5F13_10015	COG0124	histidyl-tRNA synthetase
C5F13_10020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C5F13_10030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C5F13_10035	COG0105	UTP biosynthetic process
C5F13_10040	COG0525	valine-tRNA ligase activity
C5F13_10055	COG0642	Histidine kinase
C5F13_10080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5F13_10085	COG0336	Belongs to the RNA methyltransferase TrmD family
C5F13_10090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C5F13_10095	COG0228	four-way junction DNA binding
C5F13_10105	COG0425	Belongs to the sulfur carrier protein TusA family
C5F13_10110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C5F13_10155	COG0154	amidase activity
C5F13_10160	COG4172	Belongs to the ABC transporter superfamily
C5F13_10165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_10170	COG0601	transmembrane transport
C5F13_10175	COG0747	negative chemotaxis
C5F13_10200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_10210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C5F13_10230	COG3395	kinase activity
C5F13_10245	COG1024	Enoyl-CoA hydratase
C5F13_10265	COG0633	Ferredoxin
C5F13_10270	COG0443	Heat shock 70 kDa protein
C5F13_10275	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C5F13_10280	COG0316	Belongs to the HesB IscA family
C5F13_10285	COG0822	iron-sulfur transferase activity
C5F13_10290	COG1104	cysteine desulfurase activity
C5F13_10300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C5F13_10305	COG0556	nucleotide-excision repair
C5F13_10315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C5F13_10330	COG1846	Transcriptional regulator
C5F13_10350	COG0726	polysaccharide deacetylase
C5F13_10350	COG1649	PFAM Uncharacterised BCR, COG1649
C5F13_10355	COG1215	transferase activity, transferring glycosyl groups
C5F13_10365	COG1902	pentaerythritol trinitrate reductase activity
C5F13_10390	COG0251	oxidation-reduction process
C5F13_10400	COG1832	CoA-binding protein
C5F13_10405	COG1414	Transcriptional regulator
C5F13_10410	COG1902	pentaerythritol trinitrate reductase activity
C5F13_10410	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5F13_10420	COG3842	ATPase activity
C5F13_10430	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5F13_10445	COG0583	DNA-binding transcription factor activity
C5F13_10455	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_10460	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
C5F13_10465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C5F13_10480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C5F13_10485	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5F13_10510	COG0527	aspartate kinase activity
C5F13_10515	COG0037	tRNA processing
C5F13_10525	COG0825	malonyl-CoA metabolic process
C5F13_10535	COG0215	cysteine-tRNA ligase activity
C5F13_10550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5F13_10555	COG1968	undecaprenyl-diphosphatase activity
C5F13_10560	COG1253	flavin adenine dinucleotide binding
C5F13_10585	COG0668	transmembrane transport
C5F13_10635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C5F13_10650	COG2831	hemolysin activation secretion protein
C5F13_10655	COG3539	Fimbrial protein
C5F13_10660	COG3188	usher protein
C5F13_10665	COG3121	Chaperone
C5F13_10675	COG3210	domain, Protein
C5F13_10675	COG3064	Membrane
C5F13_10675	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C5F13_10680	COG2197	response regulator
C5F13_10685	COG2205	protein histidine kinase activity
C5F13_10685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_10695	COG4336	lyase activity
C5F13_10745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C5F13_10765	COG0028	Belongs to the TPP enzyme family
C5F13_10780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5F13_10790	COG1126	abc transporter atp-binding protein
C5F13_10800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_10815	COG0084	hydrolase, TatD family'
C5F13_10820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5F13_10825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C5F13_10830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5F13_10850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_10855	COG1959	2 iron, 2 sulfur cluster binding
C5F13_10860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5F13_10860	COG1017	nitric oxide dioxygenase activity
C5F13_10895	COG0488	(ABC) transporter
C5F13_10900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C5F13_10915	COG1024	Enoyl-CoA hydratase
C5F13_10920	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5F13_10925	COG0590	tRNA wobble adenosine to inosine editing
C5F13_10950	COG2212	antiporter activity
C5F13_10955	COG1863	multisubunit Na H antiporter MnhE subunit
C5F13_10960	COG0651	ATP synthesis coupled electron transport
C5F13_10965	COG1006	Multisubunit Na H antiporter MnhC subunit
C5F13_10970	COG2111	Na H antiporter
C5F13_10970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C5F13_10990	COG0583	DNA-binding transcription factor activity
C5F13_10995	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_11025	COG0431	NADPH-dependent FMN reductase
C5F13_11070	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_11075	COG0179	Fumarylacetoacetate (FAA) hydrolase
C5F13_11105	COG0625	glutathione transferase activity
C5F13_11115	COG2944	sequence-specific DNA binding
C5F13_11125	COG2197	response regulator
C5F13_11150	COG3119	arylsulfatase activity
C5F13_11185	COG0714	Associated with various cellular activities
C5F13_11205	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_11210	COG0861	Integral membrane protein TerC family
C5F13_11255	COG0300	oxidoreductase activity
C5F13_11280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C5F13_11295	COG0438	transferase activity, transferring glycosyl groups
C5F13_11315	COG0463	Glycosyl transferase, family 2
C5F13_11335	COG0783	Belongs to the Dps family
C5F13_11350	COG0583	DNA-binding transcription factor activity
C5F13_11355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C5F13_11370	COG0656	L-ascorbic acid biosynthetic process
C5F13_11380	COG0583	DNA-binding transcription factor activity
C5F13_11390	COG1840	ABC-type Fe3 transport system, periplasmic component
C5F13_11395	COG1178	ABC-type Fe3 transport system permease component
C5F13_11400	COG3842	ATPase activity
C5F13_11410	COG1741	Belongs to the pirin family
C5F13_11415	COG1741	Belongs to the pirin family
C5F13_11420	COG0583	DNA-binding transcription factor activity
C5F13_11425	COG2204	response regulator
C5F13_11430	COG3852	Histidine kinase
C5F13_11440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5F13_11450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C5F13_11455	COG2199	diguanylate cyclase activity
C5F13_11455	COG2200	EAL domain
C5F13_11460	COG0840	transmembrane signaling receptor activity
C5F13_11475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C5F13_11480	COG1561	YicC-like family, N-terminal region
C5F13_11500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C5F13_11505	COG0791	NLP P60 protein
C5F13_11510	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_11515	COG2863	cytochrome
C5F13_11520	COG3258	Cytochrome c
C5F13_11525	COG0194	GDP metabolic process
C5F13_11530	COG1758	RNA polymerase activity
C5F13_11535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5F13_11540	COG1126	abc transporter atp-binding protein
C5F13_11545	COG0765	amino acid transport
C5F13_11550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_11565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5F13_11570	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C5F13_11575	COG3539	Fimbrial protein
C5F13_11580	COG2850	peptidyl-arginine hydroxylation
C5F13_11585	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C5F13_11590	COG3360	Dodecin
C5F13_11640	COG0009	L-threonylcarbamoyladenylate synthase
C5F13_11645	COG2321	neutral zinc metallopeptidase
C5F13_11670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C5F13_11675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C5F13_11680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5F13_11690	COG1074	ATP-dependent DNA helicase activity
C5F13_11710	COG1686	Belongs to the peptidase S11 family
C5F13_11725	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C5F13_11730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C5F13_11735	COG4974	Belongs to the 'phage' integrase family
C5F13_11740	COG0583	DNA-binding transcription factor activity
C5F13_11745	COG0028	Belongs to the TPP enzyme family
C5F13_11760	COG0028	Belongs to the TPP enzyme family
C5F13_11765	COG1126	abc transporter atp-binding protein
C5F13_11770	COG0765	amino acid transport
C5F13_11785	COG1414	Transcriptional regulator
C5F13_11790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_11795	COG0009	L-threonylcarbamoyladenylate synthase
C5F13_11800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C5F13_11805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C5F13_11810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C5F13_11820	COG2944	sequence-specific DNA binding
C5F13_11830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C5F13_11885	COG1126	abc transporter atp-binding protein
C5F13_11890	COG0765	amino acid transport
C5F13_11895	COG0765	amino acid transport
C5F13_11900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_11910	COG2423	ornithine cyclodeaminase activity
C5F13_11925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5F13_11930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5F13_11940	COG0189	ligase activity
C5F13_11945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C5F13_11950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5F13_11955	COG2197	response regulator
C5F13_11975	COG3706	GGDEF domain
C5F13_11995	COG3022	response to hydroperoxide
C5F13_12010	COG0135	phosphoribosylanthranilate isomerase activity
C5F13_12025	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C5F13_12030	COG0101	tRNA pseudouridine synthase activity
C5F13_12040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C5F13_12045	COG0473	3-isopropylmalate dehydrogenase activity
C5F13_12050	COG0066	3-isopropylmalate dehydratase activity
C5F13_12055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C5F13_12065	COG1122	ATPase activity
C5F13_12100	COG3383	formate dehydrogenase (NAD+) activity
C5F13_12100	COG0243	molybdopterin cofactor binding
C5F13_12130	COG0489	protein tyrosine kinase activity
C5F13_12135	COG0746	molybdenum cofactor guanylyltransferase activity
C5F13_12140	COG0303	'Molybdopterin
C5F13_12145	COG1763	Mo-molybdopterin cofactor biosynthetic process
C5F13_12150	COG4783	chaperone-mediated protein folding
C5F13_12155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C5F13_12160	COG5001	Diguanylate cyclase
C5F13_12180	COG3842	ATPase activity
C5F13_12190	COG0406	alpha-ribazole phosphatase activity
C5F13_12200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C5F13_12205	COG0505	Belongs to the CarA family
C5F13_12210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C5F13_12245	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C5F13_12250	COG1960	acyl-CoA dehydrogenase activity
C5F13_12260	COG2867	negative regulation of translational initiation
C5F13_12270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C5F13_12275	COG3706	GGDEF domain
C5F13_12280	COG0330	HflC and HflK could
C5F13_12295	COG0519	Catalyzes the synthesis of GMP from XMP
C5F13_12295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5F13_12305	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C5F13_12310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5F13_12315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C5F13_12320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5F13_12330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5F13_12335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5F13_12340	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C5F13_12345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5F13_12350	COG0750	zinc metalloprotease
C5F13_12355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C5F13_12365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C5F13_12370	COG0233	cytoplasmic translational termination
C5F13_12375	COG0528	UMP kinase activity
C5F13_12380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C5F13_12385	COG0052	Belongs to the universal ribosomal protein uS2 family
C5F13_12390	COG0024	Methionine aminopeptidase
C5F13_12395	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C5F13_12425	COG0285	dihydrofolate synthase activity
C5F13_12460	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5F13_12470	COG1677	Flagellar hook-basal body complex protein FliE
C5F13_12480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5F13_12490	COG1157	protein secretion by the type III secretion system
C5F13_12515	COG1580	Controls the rotational direction of flagella during chemotaxis
C5F13_12535	COG1338	Plays a role in the flagellum-specific transport system
C5F13_12555	COG0840	transmembrane signaling receptor activity
C5F13_12560	COG0840	transmembrane signaling receptor activity
C5F13_12565	COG0840	transmembrane signaling receptor activity
C5F13_12575	COG1256	bacterial-type flagellum assembly
C5F13_12585	COG1706	bacterial-type flagellum-dependent cell motility
C5F13_12590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C5F13_12595	COG4786	Flagellar basal body rod
C5F13_12605	COG1749	Flagellar hook protein flgE
C5F13_12610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C5F13_12615	COG1558	bacterial-type flagellum-dependent cell motility
C5F13_12620	COG1815	bacterial-type flagellum-dependent cell motility
C5F13_12660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_12670	COG1126	abc transporter atp-binding protein
C5F13_12685	COG4948	Mandelate Racemase Muconate Lactonizing
C5F13_12690	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_12700	COG0066	3-isopropylmalate dehydratase activity
C5F13_12715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_12725	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_12735	COG1802	Transcriptional regulator
C5F13_12750	COG0583	DNA-binding transcription factor activity
C5F13_12770	COG1695	Transcriptional regulator
C5F13_12780	COG3568	Endonuclease Exonuclease Phosphatase
C5F13_12785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5F13_12835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C5F13_12845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C5F13_12865	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C5F13_12895	COG0667	Aldo Keto reductase
C5F13_12910	COG2259	Doxx family
C5F13_12940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_12960	COG0386	Belongs to the glutathione peroxidase family
C5F13_12965	COG0625	glutathione transferase activity
C5F13_12980	COG0095	Lipoate-protein ligase
C5F13_13020	COG2363	Small membrane protein
C5F13_13045	COG3842	ATPase activity
C5F13_13050	COG0395	ABC-type sugar transport system, permease component
C5F13_13055	COG1175	transmembrane transport
C5F13_13060	COG1653	transport
C5F13_13070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C5F13_13085	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_13105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C5F13_13135	COG2311	Membrane
C5F13_13150	COG0187	DNA topoisomerase II activity
C5F13_13160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C5F13_13170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C5F13_13175	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C5F13_13180	COG1760	l-serine dehydratase
C5F13_13185	COG1283	sodium-dependent phosphate transmembrane transporter activity
C5F13_13190	COG0412	Dienelactone hydrolase
C5F13_13205	COG1611	Belongs to the LOG family
C5F13_13225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C5F13_13230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C5F13_13235	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C5F13_13240	COG2251	uridine kinase activity
C5F13_13240	COG0195	Participates in both transcription termination and antitermination
C5F13_13245	COG0779	Required for maturation of 30S ribosomal subunits
C5F13_13250	COG1187	pseudouridine synthase activity
C5F13_13255	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C5F13_13265	COG0583	DNA-binding transcription factor activity
C5F13_13275	COG0523	cobalamin synthesis protein
C5F13_13295	COG0625	glutathione transferase activity
C5F13_13305	COG1047	Peptidyl-prolyl cis-trans
C5F13_13310	COG2003	Belongs to the UPF0758 family
C5F13_13315	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C5F13_13320	COG3483	tryptophan 2,3-dioxygenase activity
C5F13_13325	COG0254	rRNA binding
C5F13_13335	COG0534	Mate efflux family protein
C5F13_13355	COG2304	oxidoreductase activity
C5F13_13375	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_13380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5F13_13385	COG1562	ergosterol biosynthetic process
C5F13_13390	COG1562	ergosterol biosynthetic process
C5F13_13395	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C5F13_13395	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C5F13_13400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C5F13_13410	COG0842	Transport permease protein
C5F13_13415	COG1131	(ABC) transporter
C5F13_13435	COG1477	protein flavinylation
C5F13_13450	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C5F13_13465	COG5564	TIM-barrel signal transduction protein
C5F13_13470	COG5441	Belongs to the UPF0261 family
C5F13_13480	COG3468	outer membrane autotransporter barrel domain protein
C5F13_13500	COG0542	response to heat
C5F13_13505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5F13_13520	COG0494	nUDIX hydrolase
C5F13_13525	COG3530	Putative quorum-sensing-regulated virulence factor
C5F13_13535	COG1595	DNA-templated transcription, initiation
C5F13_13540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5F13_13575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_13580	COG0765	amino acid transport
C5F13_13585	COG0765	amino acid transport
C5F13_13615	COG3539	Fimbrial protein
C5F13_13625	COG2050	protein possibly involved in aromatic compounds catabolism
C5F13_13630	COG1024	Enoyl-CoA hydratase
C5F13_13635	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_13655	COG2151	metal-sulfur cluster biosynthetic enzyme
C5F13_13660	COG3396	Phenylacetate-CoA oxygenase
C5F13_13665	COG3460	Phenylacetate-CoA oxygenase
C5F13_13670	COG3396	Phenylacetate-CoA oxygenase
C5F13_13675	COG3327	negative regulation of DNA-templated transcription, initiation
C5F13_13685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C5F13_13690	COG0501	Belongs to the peptidase M48B family
C5F13_13695	COG1162	GTPase activity
C5F13_13710	COG0601	transmembrane transport
C5F13_13715	COG0747	negative chemotaxis
C5F13_13760	COG0668	transmembrane transport
C5F13_13765	COG0165	Argininosuccinate lyase
C5F13_13785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C5F13_13790	COG0303	'Molybdopterin
C5F13_13795	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5F13_13810	COG0315	cyclic pyranopterin monophosphate synthase activity
C5F13_13820	COG0412	Dienelactone hydrolase
C5F13_13830	COG0678	peroxiredoxin activity
C5F13_13840	COG0697	spore germination
C5F13_13845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C5F13_13870	COG0789	Transcriptional regulator
C5F13_13890	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_13900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C5F13_13905	COG1845	cytochrome c oxidase, subunit III
C5F13_13910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5F13_13920	COG0477	Major facilitator Superfamily
C5F13_13955	COG1309	transcriptional regulator
C5F13_13960	COG2271	Major facilitator Superfamily
C5F13_13980	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_13995	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5F13_13995	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5F13_13995	COG0506	proline dehydrogenase activity
C5F13_14005	COG3008	intermembrane lipid transfer
C5F13_14005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C5F13_14010	COG2995	paraquat-inducible protein a
C5F13_14015	COG0542	response to heat
C5F13_14020	COG4953	penicillin-binding protein 1C
C5F13_14030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C5F13_14035	COG1278	Cold shock
C5F13_14045	COG0183	Belongs to the thiolase family
C5F13_14050	COG0038	chloride channel
C5F13_14055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5F13_14060	COG1570	exodeoxyribonuclease VII activity
C5F13_14070	COG0811	peptide transport
C5F13_14075	COG0848	biopolymer transport protein
C5F13_14080	COG1663	tetraacyldisaccharide 4'-kinase activity
C5F13_14085	COG2835	tetraacyldisaccharide 4'-kinase activity
C5F13_14090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C5F13_14095	COG0563	adenylate kinase activity
C5F13_14105	COG0728	peptidoglycan biosynthetic process
C5F13_14115	COG0268	Binds directly to 16S ribosomal RNA
C5F13_14150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C5F13_14175	COG0436	Aminotransferase
C5F13_14180	COG3737	Protein of unknown function (DUF498/DUF598)
C5F13_14185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5F13_14190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C5F13_14195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C5F13_14205	COG0305	Participates in initiation and elongation during chromosome replication
C5F13_14215	COG0359	binds to the 23S rRNA
C5F13_14220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C5F13_14225	COG2965	DNA replication, synthesis of RNA primer
C5F13_14230	COG0360	Binds together with S18 to 16S ribosomal RNA
C5F13_14235	COG1469	GTP cyclohydrolase I activity
C5F13_14240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C5F13_14245	COG0142	geranyltranstransferase activity
C5F13_14250	COG1722	exodeoxyribonuclease VII activity
C5F13_14260	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_14280	COG2239	Acts as a magnesium transporter
C5F13_14285	COG1607	acyl-coa hydrolase
C5F13_14290	COG2855	membrane
C5F13_14300	COG1473	amidohydrolase
C5F13_14305	COG0318	PFAM AMP-dependent synthetase and ligase
C5F13_14330	COG1501	Belongs to the glycosyl hydrolase 31 family
C5F13_14335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C5F13_14340	COG2011	ABC-type metal ion transport system permease component
C5F13_14360	COG1454	alcohol dehydrogenase
C5F13_14390	COG2186	Transcriptional regulator
C5F13_14395	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_14415	COG1175	transmembrane transport
C5F13_14420	COG0395	ABC-type sugar transport system, permease component
C5F13_14425	COG3842	ATPase activity
C5F13_14440	COG1653	transport
C5F13_14460	COG2818	Glycosylase
C5F13_14465	COG2982	Protein involved in outer membrane biogenesis
C5F13_14475	COG1309	transcriptional regulator
C5F13_14480	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_14540	COG0583	DNA-binding transcription factor activity
C5F13_14545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C5F13_14550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C5F13_14565	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_14570	COG0477	Major facilitator Superfamily
C5F13_14580	COG0583	DNA-binding transcription factor activity
C5F13_14585	COG1448	Aminotransferase
C5F13_14590	COG1418	mRNA catabolic process
C5F13_14615	COG1063	alcohol dehydrogenase
C5F13_14635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_14645	COG0318	PFAM AMP-dependent synthetase and ligase
C5F13_14655	COG1522	sequence-specific DNA binding
C5F13_14660	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_14665	COG0307	riboflavin synthase, alpha
C5F13_14670	COG0154	amidase activity
C5F13_14690	COG2807	transmembrane transport
C5F13_14695	COG0590	tRNA wobble adenosine to inosine editing
C5F13_14705	COG0583	DNA-binding transcription factor activity
C5F13_14725	COG0410	ABC transporter
C5F13_14740	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_14745	COG0251	oxidation-reduction process
C5F13_14750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5F13_14760	COG1414	Transcriptional regulator
C5F13_14765	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_14780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_14795	COG1024	Enoyl-CoA hydratase
C5F13_14800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_14805	COG0154	amidase activity
C5F13_14845	COG3909	cytochrome
C5F13_14850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C5F13_14855	COG0625	glutathione transferase activity
C5F13_14860	COG0730	response to heat
C5F13_14865	COG0482	sulfurtransferase activity
C5F13_14870	COG0583	DNA-binding transcription factor activity
C5F13_14885	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C5F13_14895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C5F13_14910	COG2819	hydrolase of the alpha beta superfamily
C5F13_14915	COG0247	lactate metabolic process
C5F13_14920	COG0277	FAD linked oxidase domain protein
C5F13_14925	COG0277	FAD linked oxidase domain protein
C5F13_14930	COG0277	FAD linked oxidase domain protein
C5F13_14935	COG3210	domain, Protein
C5F13_14935	COG3064	Membrane
C5F13_14935	COG3210	domain, Protein
C5F13_14935	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C5F13_14935	COG3064	Membrane
C5F13_14935	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C5F13_14940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5F13_14945	COG0312	modulator of DNA gyrase
C5F13_14950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5F13_15025	COG3220	belongs to the UPF0276 family
C5F13_15045	COG0640	Transcriptional regulator
C5F13_15050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C5F13_15055	COG1845	cytochrome c oxidase, subunit III
C5F13_15060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5F13_15070	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C5F13_15110	COG0583	DNA-binding transcription factor activity
C5F13_15145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5F13_15145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5F13_15160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C5F13_15165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C5F13_15175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5F13_15190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C5F13_15195	COG0316	Belongs to the HesB IscA family
C5F13_15205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C5F13_15210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C5F13_15215	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C5F13_15220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C5F13_15225	COG0312	modulator of DNA gyrase
C5F13_15230	COG3028	Belongs to the UPF0307 family
C5F13_15245	COG1116	anion transmembrane transporter activity
C5F13_15250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_15255	COG1335	isochorismatase
C5F13_15260	COG0346	lactoylglutathione lyase activity
C5F13_15265	COG0513	Belongs to the DEAD box helicase family
C5F13_15270	COG3069	C4-dicarboxylate transmembrane transporter activity
C5F13_15275	COG1802	Transcriptional regulator
C5F13_15290	COG0045	succinate-CoA ligase (ADP-forming) activity
C5F13_15290	COG1042	CoA-binding domain protein
C5F13_15290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5F13_15295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5F13_15310	COG1522	sequence-specific DNA binding
C5F13_15345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5F13_15350	COG1696	Membrane protein involved in D-alanine export
C5F13_15390	COG0439	Biotin carboxylase
C5F13_15395	COG0511	ligase activity, forming carbon-carbon bonds
C5F13_15400	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C5F13_15405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5F13_15410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5F13_15415	COG3150	esterase
C5F13_15420	COG0557	exoribonuclease II activity
C5F13_15430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5F13_15450	COG1522	sequence-specific DNA binding
C5F13_15455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_15460	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_15480	COG0653	protein targeting
C5F13_15485	COG0739	heme binding
C5F13_15495	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C5F13_15500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C5F13_15510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C5F13_15515	COG1181	Belongs to the D-alanine--D-alanine ligase family
C5F13_15520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5F13_15525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5F13_15535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C5F13_15540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5F13_15545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C5F13_15555	COG3116	cell division
C5F13_15560	COG0275	rRNA processing
C5F13_15565	COG2001	Belongs to the MraZ family
C5F13_15580	COG0418	dihydroorotase activity
C5F13_15585	COG1473	amidohydrolase
C5F13_15625	COG1522	sequence-specific DNA binding
C5F13_15635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5F13_15640	COG4654	Cytochrome c, class I
C5F13_15645	COG0129	dihydroxy-acid dehydratase activity
C5F13_15650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C5F13_15700	COG2084	Dehydrogenase
C5F13_15720	COG2096	Adenosyltransferase
C5F13_15735	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C5F13_15740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C5F13_15745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5F13_15750	COG0523	cobalamin synthesis protein
C5F13_15755	COG0735	belongs to the Fur family
C5F13_15765	COG1121	(ABC) transporter
C5F13_15775	COG0803	Belongs to the bacterial solute-binding protein 9 family
C5F13_15785	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C5F13_15795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C5F13_15805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C5F13_15810	COG1560	Kdo2-lipid A biosynthetic process
C5F13_15820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C5F13_15835	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C5F13_15840	COG1950	PFAM Membrane protein of
C5F13_15855	COG0583	DNA-binding transcription factor activity
C5F13_15865	COG0477	Major facilitator Superfamily
C5F13_15880	COG0617	tRNA 3'-terminal CCA addition
C5F13_15890	COG0513	Belongs to the DEAD box helicase family
C5F13_15895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C5F13_15905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5F13_15910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C5F13_15985	COG0405	Gamma-glutamyltransferase
C5F13_15995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_16025	COG1309	transcriptional regulator
C5F13_16040	COG0745	RESPONSE REGULATOR receiver
C5F13_16090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C5F13_16115	COG0582	viral genome integration into host DNA
C5F13_16120	COG0012	GTP binding
C5F13_16130	COG0193	aminoacyl-tRNA hydrolase activity
C5F13_16135	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C5F13_16140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5F13_16150	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C5F13_16155	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C5F13_16165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C5F13_16190	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C5F13_16200	COG1368	sulfuric ester hydrolase activity
C5F13_16205	COG0642	Histidine kinase
C5F13_16210	COG0745	RESPONSE REGULATOR receiver
C5F13_16215	COG0277	FAD linked oxidase domain protein
C5F13_16230	COG0166	Belongs to the GPI family
C5F13_16235	COG0438	transferase activity, transferring glycosyl groups
C5F13_16240	COG0438	transferase activity, transferring glycosyl groups
C5F13_16255	COG0438	transferase activity, transferring glycosyl groups
C5F13_16270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C5F13_16275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5F13_16280	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
C5F13_16290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C5F13_16300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5F13_16315	COG0747	negative chemotaxis
C5F13_16320	COG0601	transmembrane transport
C5F13_16325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_16345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C5F13_16350	COG0830	nickel cation binding
C5F13_16360	COG0804	urea catabolic process
C5F13_16365	COG0832	Belongs to the urease beta subunit family
C5F13_16375	COG0831	urea catabolic process
C5F13_16380	COG0829	nickel cation binding
C5F13_16405	COG2188	Transcriptional regulator
C5F13_16430	COG2719	SpoVR family
C5F13_16435	COG2718	Belongs to the UPF0229 family
C5F13_16455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_16470	COG1960	acyl-CoA dehydrogenase activity
C5F13_16490	COG0411	ABC transporter
C5F13_16570	COG0328	RNA-DNA hybrid ribonuclease activity
C5F13_16575	COG2226	methyltransferase
C5F13_16585	COG0741	lytic transglycosylase activity
C5F13_16585	COG1388	LysM domain
C5F13_16605	COG2979	Protein of unknown function (DUF533)
C5F13_16625	COG0745	RESPONSE REGULATOR receiver
C5F13_16640	COG1271	oxidase subunit
C5F13_16645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5F13_16650	COG0850	regulation of cytokinetic process
C5F13_16655	COG2894	cell division
C5F13_16660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C5F13_16695	COG0601	transmembrane transport
C5F13_16705	COG1215	transferase activity, transferring glycosyl groups
C5F13_16720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5F13_16730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5F13_16750	COG0318	PFAM AMP-dependent synthetase and ligase
C5F13_16755	COG2188	Transcriptional regulator
C5F13_16760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C5F13_16765	COG2814	Major facilitator Superfamily
C5F13_16775	COG0259	pyridoxamine-phosphate oxidase activity
C5F13_16780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5F13_16795	COG0583	DNA-binding transcription factor activity
C5F13_16820	COG0134	indole-3-glycerol-phosphate synthase activity
C5F13_16825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C5F13_16830	COG0512	Glutamine amidotransferase of anthranilate synthase
C5F13_16840	COG0546	phosphoglycolate phosphatase activity
C5F13_16850	COG2967	ApaG domain
C5F13_16855	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C5F13_16860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5F13_16865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5F13_16870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5F13_16880	COG0037	tRNA processing
C5F13_16890	COG3634	alkyl hydroperoxide reductase activity
C5F13_16895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5F13_16900	COG1024	Enoyl-CoA hydratase
C5F13_16925	COG0356	it plays a direct role in the translocation of protons across the membrane
C5F13_16935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C5F13_16940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C5F13_16945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C5F13_16950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C5F13_16955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C5F13_16960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C5F13_16970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C5F13_16975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5F13_16980	COG0210	DNA helicase
C5F13_16990	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5F13_17000	COG4172	Belongs to the ABC transporter superfamily
C5F13_17005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_17010	COG0601	transmembrane transport
C5F13_17030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C5F13_17035	COG1024	Enoyl-CoA hydratase
C5F13_17040	COG1024	Enoyl-CoA hydratase
C5F13_17100	COG2132	Multicopper oxidase
C5F13_17110	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5F13_17110	COG1024	Enoyl-CoA hydratase
C5F13_17120	COG1414	Transcriptional regulator
C5F13_17130	COG0154	amidase activity
C5F13_17160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5F13_17165	COG3568	Endonuclease Exonuclease Phosphatase
C5F13_17170	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C5F13_17205	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C5F13_17215	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C5F13_17230	COG1137	ATPase activity
C5F13_17245	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C5F13_17250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C5F13_17250	COG2010	Cytochrome c
C5F13_17265	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5F13_17300	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_17310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C5F13_17315	COG2890	protein-(glutamine-N5) methyltransferase activity
C5F13_17320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C5F13_17325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C5F13_17375	COG1960	acyl-CoA dehydrogenase activity
C5F13_17385	COG0183	Belongs to the thiolase family
C5F13_17390	COG1522	sequence-specific DNA binding
C5F13_17395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C5F13_17415	COG1024	Enoyl-CoA hydratase
C5F13_17430	COG0604	alcohol dehydrogenase
C5F13_17450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5F13_17460	COG1960	acyl-CoA dehydrogenase activity
C5F13_17465	COG1960	acyl-CoA dehydrogenase activity
C5F13_17470	COG0277	FAD linked oxidase domain protein
C5F13_17480	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_17505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5F13_17515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_17520	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_17525	COG1960	acyl-CoA dehydrogenase activity
C5F13_17545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5F13_17550	COG1024	Enoyl-CoA hydratase
C5F13_17555	COG1960	acyl-CoA dehydrogenase activity
C5F13_17575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5F13_17580	COG0022	dehydrogenase e1 component
C5F13_17585	COG1024	Enoyl-CoA hydratase
C5F13_17590	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5F13_17610	COG0683	leucine binding
C5F13_17615	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_17620	COG0411	ABC transporter
C5F13_17625	COG0410	ABC transporter
C5F13_17630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5F13_17645	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_17675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5F13_17680	COG0793	Belongs to the peptidase S41A family
C5F13_17685	COG4942	peptidase
C5F13_17690	COG0588	phosphoglycerate mutase activity
C5F13_17700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C5F13_17705	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C5F13_17710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C5F13_17715	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_17730	COG2226	methyltransferase
C5F13_17735	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C5F13_17750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_17755	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C5F13_17780	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C5F13_17805	COG1335	isochorismatase
C5F13_17810	COG2309	aminopeptidase activity
C5F13_17820	COG3473	Maleate cis-trans isomerase
C5F13_17830	COG2068	MobA-Related Protein
C5F13_17850	COG0569	domain protein
C5F13_17855	COG2204	response regulator
C5F13_17860	COG5000	phosphorelay sensor kinase activity
C5F13_17870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5F13_17870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5F13_17880	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
C5F13_17915	COG0583	DNA-binding transcription factor activity
C5F13_17935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5F13_17940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_17955	COG0758	DNA mediated transformation
C5F13_17960	COG1522	sequence-specific DNA binding
C5F13_17970	COG0242	peptide deformylase activity
C5F13_17985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C5F13_17995	COG0546	phosphoglycolate phosphatase activity
C5F13_18020	COG1942	4-Oxalocrotonate Tautomerase
C5F13_18025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5F13_18050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5F13_18070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5F13_18075	COG1024	Enoyl-CoA hydratase
C5F13_18080	COG1414	Transcriptional regulator
C5F13_18085	COG0318	PFAM AMP-dependent synthetase and ligase
C5F13_18090	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_18140	COG0330	HflC and HflK could
C5F13_18150	COG0251	oxidation-reduction process
C5F13_18200	COG3723	Recombinational DNA repair protein, rece pathway
C5F13_18235	COG0582	viral genome integration into host DNA
C5F13_18270	COG0706	membrane insertase activity
C5F13_18275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C5F13_18280	COG0594	ribonuclease P activity
C5F13_18285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C5F13_18305	COG1414	Transcriptional regulator
C5F13_18310	COG0154	amidase activity
C5F13_18325	COG1304	FMN binding
C5F13_18375	COG0183	Belongs to the thiolase family
C5F13_18380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5F13_18395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5F13_18400	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_18420	COG1629	transport
C5F13_18425	COG2922	Belongs to the Smg family
C5F13_18450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C5F13_18455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_18460	COG1028	Short-chain dehydrogenase reductase Sdr
C5F13_18465	COG1012	belongs to the aldehyde dehydrogenase family
C5F13_18475	COG0028	Belongs to the TPP enzyme family
C5F13_18480	COG1522	sequence-specific DNA binding
C5F13_18485	COG3781	membrane
C5F13_18495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5F13_18515	COG4206	TonB-dependent receptor
C5F13_18520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5F13_18525	COG2022	thiamine diphosphate biosynthetic process
C5F13_18530	COG0351	phosphomethylpyrimidine kinase
C5F13_18535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C5F13_18550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C5F13_18560	COG0628	permease
C5F13_18570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5F13_18585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C5F13_18590	COG0049	tRNA binding
C5F13_18595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5F13_18600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5F13_18605	COG0051	transcription antitermination factor activity, RNA binding
C5F13_18610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C5F13_18615	COG0088	Forms part of the polypeptide exit tunnel
C5F13_18620	COG0089	rRNA binding
C5F13_18625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C5F13_18630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C5F13_18635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C5F13_18640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C5F13_18645	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C5F13_18650	COG0255	Belongs to the universal ribosomal protein uL29 family
C5F13_18655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C5F13_18675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C5F13_18680	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C5F13_18685	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C5F13_18690	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C5F13_18695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C5F13_18700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C5F13_18705	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C5F13_18710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C5F13_18715	COG1841	ribosomal large subunit assembly
C5F13_18720	COG0200	Binds to the 23S rRNA
C5F13_18725	COG0201	protein transport
C5F13_18730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C5F13_18735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5F13_18740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C5F13_18745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C5F13_18750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C5F13_18755	COG0202	RNA polymerase activity
C5F13_18760	COG0203	ribosomal protein L17
C5F13_18765	COG0537	adenosine 5'-monophosphoramidase activity
C5F13_18770	COG1324	tolerance protein
C5F13_18775	COG4232	protein-disulfide reductase activity
C5F13_18790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C5F13_18800	COG1333	cytochrome c biogenesis protein
C5F13_18805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5F13_18820	COG1965	Belongs to the frataxin family
C5F13_18835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C5F13_18840	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C5F13_18855	COG2814	Major facilitator Superfamily
C5F13_18860	COG0629	single-stranded DNA binding
C5F13_18910	COG0438	transferase activity, transferring glycosyl groups
C5F13_18930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_18955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C5F13_18980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5F13_18985	COG1956	GAF domain-containing protein
C5F13_18990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5F13_19005	COG1652	LysM domain
C5F13_19020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C5F13_19035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5F13_19065	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_19080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_19095	COG1024	Enoyl-CoA hydratase
C5F13_19110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_19115	COG1309	transcriptional regulator
C5F13_19120	COG2816	NAD+ diphosphatase activity
C5F13_19125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5F13_19165	COG0559	Belongs to the binding-protein-dependent transport system permease family
C5F13_19210	COG2814	Major facilitator Superfamily
C5F13_19215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C5F13_19235	COG1999	signal sequence binding
C5F13_19240	COG0109	protoheme IX farnesyltransferase activity
C5F13_19280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5F13_19300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C5F13_19305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C5F13_19315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C5F13_19320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C5F13_19330	COG0069	glutamate synthase activity
C5F13_19330	COG0067	glutamate synthase
C5F13_19330	COG0070	glutamate synthase
C5F13_19340	COG3047	cAMP biosynthetic process
C5F13_19350	COG1127	ABC transporter
C5F13_19355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C5F13_19360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C5F13_19365	COG2853	Lipoprotein
C5F13_19380	COG0842	Transport permease protein
C5F13_19390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5F13_19395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C5F13_19400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C5F13_19405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C5F13_19410	COG0131	Imidazoleglycerol-phosphate dehydratase
C5F13_19415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C5F13_19420	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C5F13_19425	COG0107	imidazoleglycerol-phosphate synthase activity
C5F13_19430	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C5F13_19440	COG0537	adenosine 5'-monophosphoramidase activity
C5F13_19445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5F13_19450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5F13_19465	COG3181	Tripartite tricarboxylate transporter family receptor
C5F13_19505	COG3451	type IV secretory pathway VirB4
C5F13_19525	COG3504	Conjugal transfer protein
C5F13_19530	COG2948	multi-organism process
C5F13_19545	COG0697	spore germination
C5F13_19565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C5F13_19570	COG0747	negative chemotaxis
C5F13_19580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5F13_19595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C5F13_19605	COG0494	nUDIX hydrolase
C5F13_19630	COG1538	Outer membrane efflux protein
C5F13_19650	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C5F13_19655	COG0237	dephospho-CoA kinase activity
C5F13_19660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C5F13_19675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C5F13_19680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C5F13_19690	COG0477	Major facilitator Superfamily
C5F13_19695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C5F13_19710	COG1126	abc transporter atp-binding protein
C5F13_19715	COG0765	amino acid transport
C5F13_19720	COG4597	amino acid ABC transporter
C5F13_19725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5F13_19730	COG2884	Cell division ATP-binding protein ftsE
C5F13_19735	COG2177	Part of the ABC transporter FtsEX involved in
C5F13_19740	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C5F13_19750	COG1194	a g-specific adenine glycosylase
C5F13_19760	COG2226	methyltransferase
C5F13_19770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_19775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_19790	COG1024	Enoyl-CoA hydratase
C5F13_19810	COG1024	Enoyl-CoA hydratase
C5F13_19815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5F13_19830	COG0753	catalase activity
C5F13_19835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5F13_19840	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C5F13_19850	COG2175	clavaminate synthase activity
C5F13_19855	COG1473	amidohydrolase
C5F13_19860	COG4608	Belongs to the ABC transporter superfamily
C5F13_19865	COG0444	Belongs to the ABC transporter superfamily
C5F13_19875	COG0601	transmembrane transport
C5F13_19880	COG0747	negative chemotaxis
C5F13_19885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C5F13_19900	COG5002	protein histidine kinase activity
C5F13_19900	COG3850	Histidine kinase
C5F13_19920	COG0436	Aminotransferase