locus-tag	class	description
BA6348_00010	COG2337	Toxic component of a toxin-antitoxin (TA) module
BA6348_00015	COG0864	Transcriptional regulator
BA6348_00045	COG0736	holo-[acyl-carrier-protein] synthase activity
BA6348_00105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA6348_00110	COG0581	inorganic phosphate transmembrane transporter activity
BA6348_00115	COG0573	inorganic phosphate transmembrane transporter activity
BA6348_00120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BA6348_00145	COG4166	transmembrane transport
BA6348_00150	COG4166	transmembrane transport
BA6348_00155	COG4166	transmembrane transport
BA6348_00170	COG4166	transmembrane transport
BA6348_00195	COG1316	TRANSCRIPTIONal
BA6348_00205	COG0667	Aldo Keto reductase
BA6348_00215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BA6348_00230	COG1999	signal sequence binding
BA6348_00235	COG0425	Belongs to the sulfur carrier protein TusA family
BA6348_00235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA6348_00245	COG0640	Transcriptional regulator
BA6348_00250	COG0477	Major facilitator Superfamily
BA6348_00255	COG0714	Associated with various cellular activities
BA6348_00280	COG4555	ABC transporter
BA6348_00300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_00310	COG1309	transcriptional regulator
BA6348_00315	COG1902	pentaerythritol trinitrate reductase activity
BA6348_00325	COG0372	Belongs to the citrate synthase family
BA6348_00330	COG0583	DNA-binding transcription factor activity
BA6348_00350	COG4533	DNA binding
BA6348_00360	COG0840	transmembrane signaling receptor activity
BA6348_00360	COG5278	phosphoserine phosphatase activity
BA6348_00365	COG0740	serine-type endopeptidase activity
BA6348_00380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BA6348_00385	COG1522	sequence-specific DNA binding
BA6348_00405	COG0475	glutathione-regulated potassium exporter activity
BA6348_00410	COG1929	Belongs to the glycerate kinase type-1 family
BA6348_00415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BA6348_00420	COG0523	cobalamin synthesis protein
BA6348_00430	COG4372	Transposase
BA6348_00435	COG3436	PFAM IS66 Orf2 family protein
BA6348_00470	COG0745	RESPONSE REGULATOR receiver
BA6348_00475	COG5002	protein histidine kinase activity
BA6348_00480	COG0778	Nitroreductase
BA6348_00485	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_00490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BA6348_00495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BA6348_00510	COG2197	response regulator
BA6348_00515	COG4585	Histidine kinase
BA6348_00525	COG2814	Major facilitator Superfamily
BA6348_00550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BA6348_00555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA6348_00560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA6348_00560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA6348_00560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA6348_00565	COG1105	Belongs to the carbohydrate kinase PfkB family
BA6348_00570	COG1349	DNA-binding transcription factor activity
BA6348_00580	COG1971	Probably functions as a manganese efflux pump
BA6348_00600	COG2205	protein histidine kinase activity
BA6348_00610	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BA6348_00615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BA6348_00630	COG5609	conserved protein (DUF2294)
BA6348_00635	COG3842	ATPase activity
BA6348_00640	COG4149	molybdate abc transporter
BA6348_00645	COG1840	ABC-type Fe3 transport system, periplasmic component
BA6348_00650	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BA6348_00665	COG2608	mercury ion transmembrane transporter activity
BA6348_00670	COG2217	Heavy metal translocating P-type atpase
BA6348_00675	COG2313	pseudouridylate synthase activity
BA6348_00680	COG1522	sequence-specific DNA binding
BA6348_00680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA6348_00685	COG1846	Transcriptional regulator
BA6348_00690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BA6348_00695	COG2259	Doxx family
BA6348_00700	COG1741	Belongs to the pirin family
BA6348_00710	COG2814	Major facilitator Superfamily
BA6348_00715	COG0427	acetyl-CoA hydrolase
BA6348_00725	COG3829	transcription factor binding
BA6348_00725	COG3290	protein histidine kinase activity
BA6348_00730	COG1288	antiporter activity
BA6348_00735	COG1473	amidohydrolase
BA6348_00740	COG4948	Mandelate Racemase Muconate Lactonizing
BA6348_00750	COG4841	protein insertion into membrane
BA6348_00755	COG5002	protein histidine kinase activity
BA6348_00760	COG0745	RESPONSE REGULATOR receiver
BA6348_00780	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_00785	COG2610	gluconate transmembrane transporter activity
BA6348_00790	COG3290	protein histidine kinase activity
BA6348_00790	COG3829	transcription factor binding
BA6348_00805	COG0778	Nitroreductase
BA6348_00810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_00815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_00820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_00825	COG2207	Transcriptional regulator
BA6348_00825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_00830	COG4641	Protein conserved in bacteria
BA6348_00830	COG1388	LysM domain
BA6348_00835	COG1388	LysM domain
BA6348_00835	COG4641	Protein conserved in bacteria
BA6348_00845	COG4172	Belongs to the ABC transporter superfamily
BA6348_00885	COG2217	Heavy metal translocating P-type atpase
BA6348_00900	COG5002	protein histidine kinase activity
BA6348_00900	COG3850	Histidine kinase
BA6348_00905	COG0745	RESPONSE REGULATOR receiver
BA6348_00910	COG0400	carboxylic ester hydrolase activity
BA6348_00915	COG0346	lactoylglutathione lyase activity
BA6348_00920	COG0778	Nitroreductase
BA6348_00945	COG0346	lactoylglutathione lyase activity
BA6348_00950	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BA6348_00955	COG2169	Transcriptional regulator
BA6348_00960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BA6348_00965	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BA6348_00980	COG1846	Transcriptional regulator
BA6348_00990	COG2197	response regulator
BA6348_01010	COG1063	alcohol dehydrogenase
BA6348_01020	COG1124	(ABC) transporter
BA6348_01025	COG0444	Belongs to the ABC transporter superfamily
BA6348_01030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_01035	COG0601	transmembrane transport
BA6348_01040	COG0747	negative chemotaxis
BA6348_01075	COG0456	acetyltransferase
BA6348_01080	COG2205	protein histidine kinase activity
BA6348_01085	COG5002	protein histidine kinase activity
BA6348_01095	COG2271	Major facilitator Superfamily
BA6348_01100	COG4608	Belongs to the ABC transporter superfamily
BA6348_01105	COG0444	Belongs to the ABC transporter superfamily
BA6348_01120	COG0747	negative chemotaxis
BA6348_01130	COG0583	DNA-binding transcription factor activity
BA6348_01180	COG2801	Transposase and inactivated derivatives
BA6348_01200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BA6348_01205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BA6348_01215	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BA6348_01220	COG5662	AntiSigma factor
BA6348_01225	COG1595	DNA-templated transcription, initiation
BA6348_01235	COG0010	Belongs to the arginase family
BA6348_01330	COG0726	polysaccharide deacetylase
BA6348_01335	COG2194	sulfuric ester hydrolase activity
BA6348_01345	COG0489	protein tyrosine kinase activity
BA6348_01350	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA6348_01355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BA6348_01360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BA6348_01365	COG0101	tRNA pseudouridine synthase activity
BA6348_01370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BA6348_01375	COG1122	ATPase activity
BA6348_01380	COG1122	ATPase activity
BA6348_01385	COG0203	ribosomal protein L17
BA6348_01390	COG0202	RNA polymerase activity
BA6348_01395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BA6348_01400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BA6348_01405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BA6348_01410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BA6348_01415	COG0024	Methionine aminopeptidase
BA6348_01420	COG0563	adenylate kinase activity
BA6348_01425	COG0201	protein transport
BA6348_01430	COG0200	Binds to the 23S rRNA
BA6348_01435	COG1841	ribosomal large subunit assembly
BA6348_01440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BA6348_01445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BA6348_01450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BA6348_01455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BA6348_01460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BA6348_01465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BA6348_01470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BA6348_01475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BA6348_01480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BA6348_01485	COG0255	Belongs to the universal ribosomal protein uL29 family
BA6348_01490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BA6348_01495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BA6348_01500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BA6348_01505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BA6348_01510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BA6348_01515	COG0089	rRNA binding
BA6348_01520	COG0088	Forms part of the polypeptide exit tunnel
BA6348_01525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BA6348_01530	COG0051	transcription antitermination factor activity, RNA binding
BA6348_01540	COG2346	COG2346, Truncated hemoglobins
BA6348_01545	COG0697	spore germination
BA6348_01550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BA6348_01555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BA6348_01560	COG0049	tRNA binding
BA6348_01565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BA6348_01570	COG1358	cellular component organization or biogenesis
BA6348_01575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BA6348_01580	COG0085	RNA polymerase activity
BA6348_01585	COG2813	Specifically methylates the guanine in position
BA6348_01590	COG0222	ribosome binding
BA6348_01600	COG0081	regulation of translation
BA6348_01605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BA6348_01610	COG0250	Participates in transcription elongation, termination and antitermination
BA6348_01620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BA6348_01630	COG3688	RNA-binding protein containing a PIN domain
BA6348_01635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA6348_01640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BA6348_01645	COG0215	cysteine-tRNA ligase activity
BA6348_01650	COG1045	serine acetyltransferase
BA6348_01655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BA6348_01665	COG4956	integral membrane protein (PIN domain superfamily)
BA6348_01675	COG1183	phosphatidylcholine synthase activity
BA6348_01685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BA6348_01690	COG0542	response to heat
BA6348_01695	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BA6348_01700	COG3880	PFAM UvrB UvrC protein
BA6348_01755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA6348_01765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA6348_01770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BA6348_01775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BA6348_01780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA6348_01785	COG0805	protein transport
BA6348_01790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BA6348_01860	COG0512	Glutamine amidotransferase of anthranilate synthase
BA6348_01865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BA6348_01880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA6348_01885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA6348_01890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BA6348_01895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BA6348_01900	COG4608	Belongs to the ABC transporter superfamily
BA6348_01910	COG4948	Mandelate Racemase Muconate Lactonizing
BA6348_01915	COG4166	transmembrane transport
BA6348_01920	COG0444	Belongs to the ABC transporter superfamily
BA6348_01925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_01930	COG0601	transmembrane transport
BA6348_02070	COG2894	cell division
BA6348_02150	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BA6348_02160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BA6348_02165	COG0735	belongs to the Fur family
BA6348_02170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BA6348_02175	COG1121	(ABC) transporter
BA6348_02180	COG0803	Belongs to the bacterial solute-binding protein 9 family
BA6348_02190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BA6348_02200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BA6348_02215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA6348_02225	COG0037	tRNA processing
BA6348_02230	COG3610	response to peptide
BA6348_02240	COG0515	serine threonine protein kinase
BA6348_02245	COG2304	oxidoreductase activity
BA6348_02250	COG2208	phosphoserine phosphatase activity
BA6348_02255	COG1098	S1 RNA binding domain
BA6348_02280	COG4533	DNA binding
BA6348_02295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BA6348_02300	COG3956	TIGRFAM MazG family protein
BA6348_02305	COG2244	polysaccharide biosynthetic process
BA6348_02310	COG2002	toxin-antitoxin pair type II binding
BA6348_02315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA6348_02320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BA6348_02330	COG0193	aminoacyl-tRNA hydrolase activity
BA6348_02335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BA6348_02340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BA6348_02345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BA6348_02350	COG0523	cobalamin synthesis protein
BA6348_02355	COG2088	sporulation resulting in formation of a cellular spore
BA6348_02360	COG0251	oxidation-reduction process
BA6348_02365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BA6348_02370	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BA6348_02380	COG4466	Protein conserved in bacteria
BA6348_02385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BA6348_02395	COG3584	3D domain protein
BA6348_02395	COG1388	LysM domain
BA6348_02400	COG0084	hydrolase, TatD family'
BA6348_02405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA6348_02405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA6348_02410	COG2002	toxin-antitoxin pair type II binding
BA6348_02415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BA6348_02420	COG2827	Endonuclease containing a URI domain
BA6348_02425	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BA6348_02430	COG4467	Involved in initiation control of chromosome replication
BA6348_02435	COG1774	PSP1 C-terminal conserved region
BA6348_02445	COG1728	Protein conserved in bacteria
BA6348_02450	COG3870	Protein conserved in bacteria
BA6348_02455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BA6348_02460	COG1982	Orn Lys Arg decarboxylase major
BA6348_02470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BA6348_02500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BA6348_02505	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BA6348_02510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BA6348_02515	COG3852	Histidine kinase
BA6348_02525	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BA6348_02525	COG2199	diguanylate cyclase activity
BA6348_02535	COG0586	Pfam SNARE associated Golgi protein
BA6348_02550	COG2910	NAD(P)H-binding
BA6348_02560	COG1937	Protein conserved in bacteria
BA6348_02565	COG2210	Belongs to the sulfur carrier protein TusA family
BA6348_02570	COG0730	response to heat
BA6348_02575	COG0425	Belongs to the sulfur carrier protein TusA family
BA6348_02580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA6348_02580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA6348_02585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA6348_02585	COG0425	Belongs to the sulfur carrier protein TusA family
BA6348_02605	COG1187	pseudouridine synthase activity
BA6348_02610	COG0590	tRNA wobble adenosine to inosine editing
BA6348_02620	COG3711	transcriptional antiterminator
BA6348_02625	COG2190	(PTS) system
BA6348_02630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA6348_02635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BA6348_02640	COG1263	PTS System
BA6348_02640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA6348_02640	COG2190	(PTS) system
BA6348_02655	COG1396	sequence-specific DNA binding
BA6348_02660	COG1733	regulation of RNA biosynthetic process
BA6348_02665	COG2259	Doxx family
BA6348_02690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BA6348_02695	COG1349	DNA-binding transcription factor activity
BA6348_02700	COG3842	ATPase activity
BA6348_02710	COG0395	ABC-type sugar transport system, permease component
BA6348_02725	COG2224	Isocitrate lyase
BA6348_02730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BA6348_02735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BA6348_02740	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BA6348_02745	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BA6348_02760	COG0516	GMP reductase activity
BA6348_02760	COG0517	IMP dehydrogenase activity
BA6348_02790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BA6348_02795	COG2814	Major facilitator Superfamily
BA6348_02945	COG0187	DNA topoisomerase II activity
BA6348_02955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BA6348_02960	COG2501	S4 domain
BA6348_02965	COG0592	DNA-directed DNA polymerase activity
BA6348_02970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BA6348_02980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BA6348_02990	COG0594	ribonuclease P activity
BA6348_02995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BA6348_03000	COG0706	membrane insertase activity
BA6348_03005	COG1847	R3H domain protein
BA6348_03010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BA6348_03015	COG0445	tRNA wobble uridine modification
BA6348_03020	COG0357	Ribosomal RNA small subunit methyltransferase G
BA6348_03025	COG1285	pathogenesis
BA6348_03030	COG1475	DNA binding
BA6348_03035	COG1192	Involved in chromosome partitioning
BA6348_03040	COG1475	DNA binding
BA6348_03045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BA6348_03050	COG1811	Na channel or pump
BA6348_03055	COG1597	lipid kinase activity
BA6348_03070	COG0668	transmembrane transport
BA6348_03075	COG4481	Protein conserved in bacteria
BA6348_03090	COG1164	Oligoendopeptidase f
BA6348_03100	COG0702	epimerase
BA6348_03105	COG0012	GTP binding
BA6348_03110	COG0360	Binds together with S18 to 16S ribosomal RNA
BA6348_03115	COG0629	single-stranded DNA binding
BA6348_03120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BA6348_03130	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BA6348_03135	COG0359	binds to the 23S rRNA
BA6348_03140	COG0305	Participates in initiation and elongation during chromosome replication
BA6348_03145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BA6348_03160	COG0739	heme binding
BA6348_03165	COG0745	RESPONSE REGULATOR receiver
BA6348_03170	COG5002	protein histidine kinase activity
BA6348_03180	COG4853	Protein conserved in bacteria
BA6348_03185	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BA6348_03195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA6348_03205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BA6348_03225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BA6348_03365	COG2826	transposase and inactivated derivatives, IS30 family
BA6348_03405	COG1136	(ABC) transporter
BA6348_03405	COG0577	efflux transmembrane transporter activity
BA6348_03425	COG4977	sequence-specific DNA binding
BA6348_03435	COG2819	hydrolase of the alpha beta superfamily
BA6348_03445	COG0745	RESPONSE REGULATOR receiver
BA6348_03450	COG2205	protein histidine kinase activity
BA6348_03455	COG1113	amino acid transport
BA6348_03480	COG3284	Transcriptional regulator
BA6348_03485	COG0095	Lipoate-protein ligase
BA6348_03490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BA6348_03495	COG0022	dehydrogenase e1 component
BA6348_03500	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA6348_03505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA6348_03510	COG2205	protein histidine kinase activity
BA6348_03510	COG2770	Histidine kinase
BA6348_03515	COG0745	RESPONSE REGULATOR receiver
BA6348_03520	COG1126	abc transporter atp-binding protein
BA6348_03525	COG0765	amino acid transport
BA6348_03530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA6348_03535	COG1115	amino acid carrier protein
BA6348_03540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BA6348_03545	COG2824	Alkylphosphonate utilization operon protein PhnA
BA6348_03570	COG0372	Belongs to the citrate synthase family
BA6348_03575	COG2079	MmgE PrpD family protein
BA6348_03580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BA6348_03595	COG1024	Enoyl-CoA hydratase
BA6348_03615	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BA6348_03620	COG2204	response regulator
BA6348_03625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BA6348_03630	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_03645	COG2076	Multidrug Resistance protein
BA6348_03650	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BA6348_03655	COG0672	)-iron permease
BA6348_03660	COG2837	iron assimilation
BA6348_03665	COG2822	iron ion transport
BA6348_03670	COG2186	Transcriptional regulator
BA6348_03675	COG1556	Lactate utilization protein
BA6348_03680	COG1139	Iron-sulfur cluster binding protein
BA6348_03700	COG0647	UMP catabolic process
BA6348_03705	COG3842	ATPase activity
BA6348_03710	COG1653	transport
BA6348_03720	COG0395	ABC-type sugar transport system, permease component
BA6348_03735	COG0583	DNA-binding transcription factor activity
BA6348_03745	COG0601	transmembrane transport
BA6348_03750	COG0444	Belongs to the ABC transporter superfamily
BA6348_03770	COG2884	Cell division ATP-binding protein ftsE
BA6348_03800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BA6348_03805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_03810	COG1649	PFAM Uncharacterised BCR, COG1649
BA6348_03830	COG1280	lysine exporter protein (LysE YggA)
BA6348_03885	COG0643	Histidine kinase
BA6348_03885	COG2198	Histidine kinase
BA6348_03890	COG2201	protein-glutamate methylesterase activity
BA6348_03905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_03910	COG4605	iron ion homeostasis
BA6348_03915	COG4604	ABC transporter, ATP-binding protein
BA6348_03920	COG4607	ABC-type enterochelin transport system periplasmic component
BA6348_03925	COG1120	ATPase activity
BA6348_03940	COG2011	ABC-type metal ion transport system permease component
BA6348_03950	COG1464	Belongs to the NlpA lipoprotein family
BA6348_03970	COG1176	ABC-type spermidine putrescine transport system, permease component I
BA6348_03980	COG3842	ATPase activity
BA6348_03985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BA6348_03990	COG2079	MmgE PrpD family protein
BA6348_03995	COG1126	abc transporter atp-binding protein
BA6348_04000	COG0765	amino acid transport
BA6348_04005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA6348_04020	COG0534	Mate efflux family protein
BA6348_04025	COG1285	pathogenesis
BA6348_04065	COG0514	ATP-dependent DNA helicase (RecQ)
BA6348_04070	COG0477	Major facilitator Superfamily
BA6348_04090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BA6348_04090	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BA6348_04105	COG3394	polysaccharide catabolic process
BA6348_04110	COG1447	Phosphotransferase system cellobiose-specific component IIA
BA6348_04115	COG1486	melibiose metabolic process
BA6348_04120	COG0561	phosphatase activity
BA6348_04125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA6348_04130	COG2205	protein histidine kinase activity
BA6348_04140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA6348_04155	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_04175	COG3284	Transcriptional regulator
BA6348_04180	COG3290	protein histidine kinase activity
BA6348_04180	COG3829	transcription factor binding
BA6348_04185	COG0473	3-isopropylmalate dehydrogenase activity
BA6348_04190	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_04195	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_04200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BA6348_04205	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BA6348_04215	COG0277	FAD linked oxidase domain protein
BA6348_04230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA6348_04235	COG0513	Belongs to the DEAD box helicase family
BA6348_04260	COG3711	transcriptional antiterminator
BA6348_04265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA6348_04270	COG0246	Mannitol dehydrogenase
BA6348_04280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA6348_04285	COG3119	arylsulfatase activity
BA6348_04305	COG4816	utilization protein
BA6348_04315	COG1454	alcohol dehydrogenase
BA6348_04315	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_04320	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BA6348_04325	COG4869	propanediol catabolic process
BA6348_04335	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BA6348_04340	COG4810	utilization protein
BA6348_04365	COG4303	Ethanolamine ammonia lyase large subunit
BA6348_04370	COG4302	ethanolamine ammonia-lyase activity
BA6348_04375	COG0039	L-malate dehydrogenase activity
BA6348_04385	COG2309	aminopeptidase activity
BA6348_04400	COG1765	OsmC-like protein
BA6348_04405	COG4187	Peptidase family M20/M25/M40
BA6348_04410	COG1414	Transcriptional regulator
BA6348_04420	COG0833	amino acid
BA6348_04440	COG1846	Transcriptional regulator
BA6348_04450	COG0840	transmembrane signaling receptor activity
BA6348_04475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BA6348_04490	COG0659	secondary active sulfate transmembrane transporter activity
BA6348_04500	COG0546	phosphoglycolate phosphatase activity
BA6348_04510	COG1175	transmembrane transport
BA6348_04520	COG1653	transport
BA6348_04525	COG0584	glycerophosphoryl diester phosphodiesterase
BA6348_04535	COG0405	Gamma-glutamyltransferase
BA6348_04550	COG0531	amino acid
BA6348_04575	COG0626	cystathionine gamma-synthase activity
BA6348_04580	COG2204	response regulator
BA6348_04585	COG2329	Antibiotic biosynthesis monooxygenase
BA6348_04595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BA6348_04605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BA6348_04605	COG0543	2 iron, 2 sulfur cluster binding
BA6348_04615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BA6348_04620	COG0116	Belongs to the methyltransferase superfamily
BA6348_04645	COG0564	pseudouridine synthase activity
BA6348_04650	COG0789	Transcriptional regulator
BA6348_04660	COG1309	transcriptional regulator
BA6348_04680	COG1078	dGTPase activity
BA6348_04685	COG3465	dGTPase activity
BA6348_04725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA6348_04730	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BA6348_04735	COG0010	Belongs to the arginase family
BA6348_04755	COG3829	transcription factor binding
BA6348_04760	COG1509	lysine 2,3-aminomutase activity
BA6348_04765	COG0247	lactate metabolic process
BA6348_04765	COG2181	nitrate reductase activity
BA6348_04770	COG0183	Belongs to the thiolase family
BA6348_04775	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA6348_04780	COG1960	acyl-CoA dehydrogenase activity
BA6348_04785	COG1960	acyl-CoA dehydrogenase activity
BA6348_04790	COG1309	transcriptional regulator
BA6348_04795	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BA6348_04795	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BA6348_04795	COG1703	isobutyryl-CoA mutase activity
BA6348_04800	COG0450	alkyl hydroperoxide reductase
BA6348_04810	COG3343	RNA polymerase activity
BA6348_04815	COG0504	CTP synthase activity
BA6348_04830	COG2204	response regulator
BA6348_04835	COG0191	fructose-bisphosphate aldolase activity
BA6348_04840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BA6348_04845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BA6348_04850	COG1494	fructose-1,6-bisphosphatase
BA6348_04855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BA6348_04860	COG0739	heme binding
BA6348_04870	COG0254	rRNA binding
BA6348_04880	COG1435	thymidine kinase activity
BA6348_04890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BA6348_04895	COG2890	protein-(glutamine-N5) methyltransferase activity
BA6348_04910	COG0009	L-threonylcarbamoyladenylate synthase
BA6348_04915	COG1971	Probably functions as a manganese efflux pump
BA6348_04925	COG0698	ribose 5-phosphate isomerase
BA6348_04930	COG4475	Protein of unknown function (DUF436)
BA6348_04945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BA6348_04950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BA6348_04960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA6348_04970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BA6348_04975	COG0156	8-amino-7-oxononanoate synthase activity
BA6348_04980	COG0596	Alpha beta hydrolase
BA6348_04985	COG4106	trans-aconitate 2-methyltransferase activity
BA6348_05005	COG0356	it plays a direct role in the translocation of protons across the membrane
BA6348_05020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BA6348_05025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BA6348_05030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BA6348_05035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BA6348_05040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BA6348_05050	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA6348_05055	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA6348_05060	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA6348_05065	COG0649	NAD binding
BA6348_05070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BA6348_05075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA6348_05085	COG0713	ATP synthesis coupled electron transport
BA6348_05090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BA6348_05095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA6348_05100	COG1007	ATP synthesis coupled electron transport
BA6348_05115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BA6348_05120	COG2385	sporulation resulting in formation of a cellular spore
BA6348_05125	COG0739	heme binding
BA6348_05130	COG1609	Transcriptional regulator
BA6348_05140	COG4786	Flagellar basal body rod
BA6348_05160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BA6348_05165	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BA6348_05170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA6348_05180	COG1739	Uncharacterized protein family UPF0029
BA6348_05190	COG2373	Large extracellular alpha-helical protein
BA6348_05195	COG0544	peptidyl-prolyl cis-trans isomerase activity
BA6348_05210	COG4974	Belongs to the 'phage' integrase family
BA6348_05215	COG1476	TRANSCRIPTIONal
BA6348_05235	COG2003	Belongs to the UPF0758 family
BA6348_05265	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BA6348_05275	COG1215	transferase activity, transferring glycosyl groups
BA6348_05280	COG1011	Hydrolase
BA6348_05295	COG0697	spore germination
BA6348_05320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BA6348_05325	COG1649	PFAM Uncharacterised BCR, COG1649
BA6348_05325	COG0726	polysaccharide deacetylase
BA6348_05335	COG2197	response regulator
BA6348_05345	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BA6348_05370	COG4786	Flagellar basal body rod
BA6348_05370	COG1256	bacterial-type flagellum assembly
BA6348_05375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA6348_05385	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BA6348_05390	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BA6348_05415	COG1334	flagellar protein FlaG
BA6348_05420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BA6348_05425	COG1516	flagellar protein fliS
BA6348_05460	COG0765	amino acid transport
BA6348_05465	COG1278	Cold shock
BA6348_05475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BA6348_05480	COG0653	protein targeting
BA6348_05510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BA6348_05515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BA6348_05520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA6348_05525	COG0505	Belongs to the CarA family
BA6348_05535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BA6348_05545	COG2199	diguanylate cyclase activity
BA6348_05545	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BA6348_05555	COG0137	argininosuccinate synthase activity
BA6348_05560	COG0165	Argininosuccinate lyase
BA6348_05565	COG0814	amino acid
BA6348_05595	COG1979	alcohol dehydrogenase
BA6348_05600	COG2884	Cell division ATP-binding protein ftsE
BA6348_05605	COG2177	Part of the ABC transporter FtsEX involved in
BA6348_05610	COG0739	heme binding
BA6348_05615	COG3409	Peptidoglycan-binding domain 1 protein
BA6348_05615	COG0793	Belongs to the peptidase S41A family
BA6348_05620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA6348_05635	COG0556	nucleotide-excision repair
BA6348_05640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BA6348_05645	COG1418	mRNA catabolic process
BA6348_05650	COG1950	PFAM Membrane protein of
BA6348_05660	COG2205	protein histidine kinase activity
BA6348_05665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BA6348_05670	COG0110	maltose O-acetyltransferase activity
BA6348_05675	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BA6348_05680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BA6348_05685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BA6348_05690	COG0131	Imidazoleglycerol-phosphate dehydratase
BA6348_05695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BA6348_05700	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BA6348_05705	COG0107	imidazoleglycerol-phosphate synthase activity
BA6348_05710	COG0140	phosphoribosyl-ATP diphosphatase activity
BA6348_05710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BA6348_05715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA6348_05770	COG0492	ferredoxin-NADP+ reductase activity
BA6348_05775	COG1660	Displays ATPase and GTPase activities
BA6348_05780	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BA6348_05785	COG1481	regulation of sporulation
BA6348_05790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA6348_05830	COG4191	Histidine kinase
BA6348_05840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BA6348_05865	COG0126	phosphoglycerate kinase activity
BA6348_05870	COG0149	triose-phosphate isomerase activity
BA6348_05880	COG0148	phosphopyruvate hydratase activity
BA6348_05890	COG1120	ATPase activity
BA6348_05895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_05900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_05905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_05915	COG1595	DNA-templated transcription, initiation
BA6348_05920	COG0390	transport system, permease component
BA6348_05925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA6348_05935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA6348_05940	COG0557	exoribonuclease II activity
BA6348_05945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BA6348_05995	COG1414	Transcriptional regulator
BA6348_06010	COG5002	protein histidine kinase activity
BA6348_06020	COG1129	ABC transporter
BA6348_06025	COG4214	carbohydrate transport
BA6348_06040	COG0024	Methionine aminopeptidase
BA6348_06045	COG0519	Catalyzes the synthesis of GMP from XMP
BA6348_06065	COG2826	transposase and inactivated derivatives, IS30 family
BA6348_06085	COG4191	Histidine kinase
BA6348_06115	COG3706	GGDEF domain
BA6348_06115	COG0745	RESPONSE REGULATOR receiver
BA6348_06125	COG4895	conserved protein (DUF2196)
BA6348_06140	COG1510	regulation of RNA biosynthetic process
BA6348_06145	COG4175	Glycine betaine
BA6348_06145	COG0517	IMP dehydrogenase activity
BA6348_06205	COG0586	Pfam SNARE associated Golgi protein
BA6348_06215	COG1566	PFAM secretion protein HlyD family protein
BA6348_06220	COG2814	Major facilitator Superfamily
BA6348_06270	COG2140	Oxalate decarboxylase
BA6348_06280	COG3226	Transcriptional regulator
BA6348_06300	COG1785	Belongs to the alkaline phosphatase family
BA6348_06305	COG1205	dead DEAH box helicase
BA6348_06305	COG1111	helicase
BA6348_06310	COG3359	exonuclease
BA6348_06330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_06340	COG2076	Multidrug Resistance protein
BA6348_06350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BA6348_06360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BA6348_06365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BA6348_06370	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BA6348_06385	COG1131	(ABC) transporter
BA6348_06420	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_06440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BA6348_06450	COG2050	protein possibly involved in aromatic compounds catabolism
BA6348_06455	COG2050	protein possibly involved in aromatic compounds catabolism
BA6348_06460	COG1024	Enoyl-CoA hydratase
BA6348_06465	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BA6348_06475	COG1024	Enoyl-CoA hydratase
BA6348_06480	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA6348_06485	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA6348_06495	COG0183	Belongs to the thiolase family
BA6348_06515	COG1172	Belongs to the binding-protein-dependent transport system permease family
BA6348_06520	COG0411	ABC transporter
BA6348_06525	COG0410	ABC transporter
BA6348_06535	COG0840	transmembrane signaling receptor activity
BA6348_06540	COG3396	Phenylacetate-CoA oxygenase
BA6348_06555	COG2151	metal-sulfur cluster biosynthetic enzyme
BA6348_06560	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_06565	COG3336	cytochrome c oxidase
BA6348_06580	COG1612	heme a metabolic process
BA6348_06590	COG0420	3'-5' exonuclease activity
BA6348_06595	COG0419	ATPase involved in DNA repair
BA6348_06600	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BA6348_06610	COG2318	DinB family
BA6348_06625	COG0528	UMP kinase activity
BA6348_06630	COG0551	DNA topoisomerase type I activity
BA6348_06630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA6348_06640	COG2828	Protein conserved in bacteria
BA6348_06645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA6348_06650	COG1131	(ABC) transporter
BA6348_06655	COG0842	Transport permease protein
BA6348_06660	COG1309	transcriptional regulator
BA6348_06665	COG0788	formyltetrahydrofolate deformylase activity
BA6348_06700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BA6348_06705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA6348_06720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BA6348_06725	COG1098	S1 RNA binding domain
BA6348_06745	COG0583	DNA-binding transcription factor activity
BA6348_06750	COG1506	peptidase
BA6348_06755	COG4191	Histidine kinase
BA6348_06770	COG2201	protein-glutamate methylesterase activity
BA6348_06780	COG0477	Major facilitator Superfamily
BA6348_06800	COG2508	Transcriptional regulator
BA6348_06800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BA6348_06805	COG0686	Belongs to the AlaDH PNT family
BA6348_06825	COG0167	dihydroorotate dehydrogenase activity
BA6348_06830	COG0310	cobalt ion transport
BA6348_06835	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
BA6348_06845	COG1122	ATPase activity
BA6348_06860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BA6348_06865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BA6348_06910	COG0306	phosphate transporter
BA6348_06915	COG1392	Phosphate transport regulator
BA6348_06920	COG1279	arginine transmembrane transporter activity
BA6348_06925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_06940	COG5577	PFAM Coat F domain
BA6348_06955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA6348_06960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BA6348_06980	COG1131	(ABC) transporter
BA6348_06995	COG1024	Enoyl-CoA hydratase
BA6348_06995	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA6348_07000	COG0183	Belongs to the thiolase family
BA6348_07005	COG1960	acyl-CoA dehydrogenase activity
BA6348_07025	COG0814	amino acid
BA6348_07035	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BA6348_07040	COG0235	Class ii aldolase
BA6348_07045	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BA6348_07050	COG1850	ribulose-bisphosphate carboxylase activity
BA6348_07055	COG1595	DNA-templated transcription, initiation
BA6348_07065	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BA6348_07075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA6348_07080	COG1132	(ABC) transporter
BA6348_07085	COG1132	(ABC) transporter
BA6348_07090	COG0477	Major facilitator Superfamily
BA6348_07095	COG2340	Cysteine-rich secretory protein family
BA6348_07105	COG0616	signal peptide processing
BA6348_07110	COG1126	abc transporter atp-binding protein
BA6348_07115	COG0726	polysaccharide deacetylase
BA6348_07130	COG1393	Belongs to the ArsC family
BA6348_07135	COG0436	Aminotransferase
BA6348_07145	COG0509	glycine decarboxylation via glycine cleavage system
BA6348_07150	COG0840	transmembrane signaling receptor activity
BA6348_07170	COG1473	amidohydrolase
BA6348_07175	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BA6348_07180	COG0396	ATPase activity
BA6348_07185	COG0719	Fe-S assembly protein
BA6348_07190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BA6348_07195	COG0822	iron-sulfur transferase activity
BA6348_07200	COG0719	Fe-S assembly protein
BA6348_07230	COG0840	transmembrane signaling receptor activity
BA6348_07250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_07265	COG0697	spore germination
BA6348_07270	COG0697	spore germination
BA6348_07285	COG2268	Band 7 protein
BA6348_07290	COG0726	polysaccharide deacetylase
BA6348_07295	COG0527	aspartate kinase activity
BA6348_07305	COG1801	Protein of unknown function DUF72
BA6348_07310	COG0730	response to heat
BA6348_07315	COG0737	Belongs to the 5'-nucleotidase family
BA6348_07325	COG3377	Domain of unknown function (DUF1805)
BA6348_07335	COG0598	Magnesium transport protein CorA
BA6348_07345	COG0840	transmembrane signaling receptor activity
BA6348_07375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA6348_07375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA6348_07385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BA6348_07385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BA6348_07440	COG0739	heme binding
BA6348_07445	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BA6348_07450	COG0693	protein deglycase activity
BA6348_07455	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BA6348_07460	COG0420	3'-5' exonuclease activity
BA6348_07470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BA6348_07480	COG4470	Protein conserved in bacteria
BA6348_07495	COG1494	fructose-1,6-bisphosphatase
BA6348_07505	COG2445	Protein of unknown function DUF86
BA6348_07525	COG0647	UMP catabolic process
BA6348_07530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BA6348_07540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA6348_07550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BA6348_07555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA6348_07560	COG0626	cystathionine gamma-synthase activity
BA6348_07565	COG4837	Protein of unknown function (DUF1462)
BA6348_07600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA6348_07610	COG1252	NADH dehydrogenase
BA6348_07620	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BA6348_07630	COG0316	Belongs to the HesB IscA family
BA6348_07695	COG0492	ferredoxin-NADP+ reductase activity
BA6348_07700	COG1252	NADH dehydrogenase
BA6348_07720	COG3584	3D domain protein
BA6348_07725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_07730	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BA6348_07740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BA6348_07745	COG1832	CoA-binding protein
BA6348_07750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BA6348_07785	COG0477	Major facilitator Superfamily
BA6348_07805	COG1175	transmembrane transport
BA6348_07810	COG0395	ABC-type sugar transport system, permease component
BA6348_07815	COG0456	acetyltransferase
BA6348_07820	COG1472	Belongs to the glycosyl hydrolase 3 family
BA6348_07825	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BA6348_07850	COG0747	negative chemotaxis
BA6348_07865	COG0444	Belongs to the ABC transporter superfamily
BA6348_07870	COG4608	Belongs to the ABC transporter superfamily
BA6348_07885	COG1414	Transcriptional regulator
BA6348_07900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BA6348_07920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_07950	COG0596	Alpha beta hydrolase
BA6348_07960	COG5002	protein histidine kinase activity
BA6348_07965	COG0745	RESPONSE REGULATOR receiver
BA6348_07975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA6348_07985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA6348_08005	COG0697	spore germination
BA6348_08010	COG0640	Transcriptional regulator
BA6348_08035	COG0095	Lipoate-protein ligase
BA6348_08065	COG0697	spore germination
BA6348_08080	COG2814	Major facilitator Superfamily
BA6348_08085	COG0477	Major facilitator Superfamily
BA6348_08095	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_08100	COG3135	benzoate transporter
BA6348_08105	COG2204	response regulator
BA6348_08160	COG4638	Rieske (2fe-2S)
BA6348_08165	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_08170	COG0517	IMP dehydrogenase activity
BA6348_08170	COG1125	glycine betaine transport
BA6348_08180	COG1732	Glycine betaine
BA6348_08195	COG0473	3-isopropylmalate dehydrogenase activity
BA6348_08200	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BA6348_08210	COG2197	response regulator
BA6348_08215	COG2843	Capsule synthesis protein
BA6348_08225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_08240	COG0601	transmembrane transport
BA6348_08250	COG0444	Belongs to the ABC transporter superfamily
BA6348_08255	COG4608	Belongs to the ABC transporter superfamily
BA6348_08260	COG5583	Uncharacterized small protein (DUF2292)
BA6348_08270	COG4166	transmembrane transport
BA6348_08280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA6348_08285	COG5002	protein histidine kinase activity
BA6348_08290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA6348_08305	COG2964	Protein conserved in bacteria
BA6348_08335	COG0531	amino acid
BA6348_08345	COG0662	Cupin 2, conserved barrel domain protein
BA6348_08370	COG0531	amino acid
BA6348_08375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BA6348_08400	COG3829	transcription factor binding
BA6348_08400	COG3290	protein histidine kinase activity
BA6348_08410	COG0813	purine-nucleoside phosphorylase activity
BA6348_08415	COG2814	Major facilitator Superfamily
BA6348_08435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA6348_08450	COG1309	transcriptional regulator
BA6348_08480	COG5002	protein histidine kinase activity
BA6348_08505	COG2084	Dehydrogenase
BA6348_08510	COG0628	permease
BA6348_08515	COG0745	RESPONSE REGULATOR receiver
BA6348_08520	COG5002	protein histidine kinase activity
BA6348_08535	COG4166	transmembrane transport
BA6348_08545	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA6348_08550	COG1357	PFAM Pentapeptide repeats (8 copies)
BA6348_08575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BA6348_08585	COG0720	synthase
BA6348_08590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BA6348_08600	COG3142	Participates in the control of copper homeostasis
BA6348_08620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA6348_08665	COG0006	proline dipeptidase activity
BA6348_08670	COG4166	transmembrane transport
BA6348_08675	COG3829	transcription factor binding
BA6348_08675	COG3290	protein histidine kinase activity
BA6348_08680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA6348_08685	COG3938	Belongs to the proline racemase family
BA6348_08690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA6348_08695	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_08700	COG3938	Belongs to the proline racemase family
BA6348_08725	COG1737	Transcriptional regulator
BA6348_08730	COG0363	glucosamine-6-phosphate deaminase activity
BA6348_08750	COG4129	membrane
BA6348_08765	COG0765	amino acid transport
BA6348_08770	COG1414	Transcriptional regulator
BA6348_08795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BA6348_08800	COG0583	DNA-binding transcription factor activity
BA6348_08815	COG1840	ABC-type Fe3 transport system, periplasmic component
BA6348_08820	COG3842	ATPase activity
BA6348_08825	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BA6348_08840	COG0165	Argininosuccinate lyase
BA6348_08845	COG2971	BadF BadG BcrA BcrD
BA6348_08850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BA6348_08865	COG0778	Nitroreductase
BA6348_08905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_08910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_08915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_08930	COG2070	2-Nitropropane dioxygenase
BA6348_08935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BA6348_08945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BA6348_08945	COG3433	isochorismatase activity
BA6348_08945	COG2226	methyltransferase
BA6348_08960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA6348_08965	COG1695	Transcriptional regulator
BA6348_08970	COG0542	response to heat
BA6348_08980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_08985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_08990	COG0697	spore germination
BA6348_09000	COG1176	ABC-type spermidine putrescine transport system, permease component I
BA6348_09005	COG1177	transmembrane transport
BA6348_09010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA6348_09015	COG0596	Alpha beta hydrolase
BA6348_09060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BA6348_09075	COG0840	transmembrane signaling receptor activity
BA6348_09080	COG0346	lactoylglutathione lyase activity
BA6348_09095	COG1595	DNA-templated transcription, initiation
BA6348_09130	COG0531	amino acid
BA6348_09135	COG0697	spore germination
BA6348_09140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BA6348_09145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BA6348_09150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA6348_09170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_09175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BA6348_09195	COG1473	amidohydrolase
BA6348_09200	COG0189	ligase activity
BA6348_09235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA6348_09245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BA6348_09250	COG2814	Major facilitator Superfamily
BA6348_09260	COG0826	peptidase U32
BA6348_09285	COG2357	RelA SpoT domain protein
BA6348_09290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA6348_09295	COG1309	transcriptional regulator
BA6348_09310	COG0601	transmembrane transport
BA6348_09315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_09320	COG0444	Belongs to the ABC transporter superfamily
BA6348_09325	COG4608	Belongs to the ABC transporter superfamily
BA6348_09330	COG4166	transmembrane transport
BA6348_09340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA6348_09340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BA6348_09370	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BA6348_09375	COG3275	phosphorelay sensor kinase activity
BA6348_09380	COG3279	Response regulator of the LytR AlgR family
BA6348_09390	COG1966	Carbon starvation protein
BA6348_09400	COG0483	inositol monophosphate 1-phosphatase activity
BA6348_09405	COG3387	PFAM Glycoside hydrolase 15-related
BA6348_09425	COG0778	Nitroreductase
BA6348_09440	COG1126	abc transporter atp-binding protein
BA6348_09445	COG0765	amino acid transport
BA6348_09450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA6348_09455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA6348_09475	COG0488	(ABC) transporter
BA6348_09510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA6348_09540	COG1131	(ABC) transporter
BA6348_09560	COG4565	transcriptional regulatory protein
BA6348_09565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BA6348_09575	COG0791	NLP P60 protein
BA6348_09580	COG0726	polysaccharide deacetylase
BA6348_09595	COG0129	dihydroxy-acid dehydratase activity
BA6348_09640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BA6348_09650	COG1587	Uroporphyrinogen-III synthase
BA6348_09650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BA6348_09655	COG0306	phosphate transporter
BA6348_09660	COG0175	sulfate reduction
BA6348_09665	COG2046	Belongs to the sulfate adenylyltransferase family
BA6348_09670	COG0529	Catalyzes the synthesis of activated sulfate
BA6348_09680	COG1674	ftsk spoiiie
BA6348_09685	COG2814	Major facilitator Superfamily
BA6348_09720	COG1316	TRANSCRIPTIONal
BA6348_09730	COG0489	protein tyrosine kinase activity
BA6348_09765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BA6348_09775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BA6348_09790	COG0500	methyltransferase
BA6348_09805	COG2207	Transcriptional regulator
BA6348_09810	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BA6348_09815	COG1228	amidohydrolase
BA6348_09820	COG0010	Belongs to the arginase family
BA6348_09825	COG0544	peptidyl-prolyl cis-trans isomerase activity
BA6348_09845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_09855	COG0656	L-ascorbic acid biosynthetic process
BA6348_09870	COG1414	Transcriptional regulator
BA6348_09895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA6348_09895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA6348_09925	COG1132	(ABC) transporter
BA6348_09930	COG0745	RESPONSE REGULATOR receiver
BA6348_09935	COG5002	protein histidine kinase activity
BA6348_09940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA6348_09945	COG0314	molybdopterin synthase activity
BA6348_09960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BA6348_09965	COG0315	cyclic pyranopterin monophosphate synthase activity
BA6348_09970	COG2814	Major facilitator Superfamily
BA6348_09975	COG0436	Aminotransferase
BA6348_09990	COG1943	Transposase
BA6348_10010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_10035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA6348_10045	COG1733	regulation of RNA biosynthetic process
BA6348_10065	COG2309	aminopeptidase activity
BA6348_10085	COG3118	belongs to the thioredoxin family
BA6348_10095	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BA6348_10095	COG1605	Chorismate mutase
BA6348_10110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BA6348_10115	COG0123	including yeast histone deacetylase and acetoin utilization protein
BA6348_10120	COG0517	IMP dehydrogenase activity
BA6348_10125	COG0454	-acetyltransferase
BA6348_10140	COG1396	sequence-specific DNA binding
BA6348_10145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BA6348_10160	COG2203	Gaf domain
BA6348_10160	COG2199	diguanylate cyclase activity
BA6348_10165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA6348_10180	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BA6348_10190	COG2081	HI0933 family
BA6348_10200	COG1363	Peptidase, m42
BA6348_10235	COG4326	sporulation control protein
BA6348_10245	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BA6348_10260	COG0747	negative chemotaxis
BA6348_10275	COG0444	Belongs to the ABC transporter superfamily
BA6348_10280	COG4608	Belongs to the ABC transporter superfamily
BA6348_10285	COG4948	Mandelate Racemase Muconate Lactonizing
BA6348_10290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA6348_10315	COG0300	oxidoreductase activity
BA6348_10325	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BA6348_10340	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BA6348_10345	COG3584	3D domain protein
BA6348_10345	COG1388	LysM domain
BA6348_10350	COG1104	cysteine desulfurase activity
BA6348_10355	COG0301	tRNA thio-modification
BA6348_10360	COG0179	Fumarylacetoacetate (FAA) hydrolase
BA6348_10460	COG4191	Histidine kinase
BA6348_10470	COG0861	Integral membrane protein TerC family
BA6348_10475	COG0726	polysaccharide deacetylase
BA6348_10480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA6348_10495	COG2323	membrane
BA6348_10505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA6348_10515	COG3773	Cell wall hydrolase
BA6348_10515	COG3409	Peptidoglycan-binding domain 1 protein
BA6348_10520	COG3584	3D domain protein
BA6348_10520	COG1388	LysM domain
BA6348_10530	COG3874	Sporulation protein YtfJ
BA6348_10540	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BA6348_10555	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BA6348_10565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA6348_10585	COG0564	pseudouridine synthase activity
BA6348_10590	COG0179	Fumarylacetoacetate (FAA) hydrolase
BA6348_10595	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BA6348_10600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BA6348_10615	COG1309	transcriptional regulator
BA6348_10620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA6348_10630	COG0024	Methionine aminopeptidase
BA6348_10635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BA6348_10655	COG0586	Pfam SNARE associated Golgi protein
BA6348_10665	COG3481	metal-dependent phosphohydrolase, HD sub domain
BA6348_10690	COG2223	nitrite transmembrane transporter activity
BA6348_10700	COG1316	TRANSCRIPTIONal
BA6348_10715	COG0446	pyridine nucleotide-disulphide oxidoreductase
BA6348_10715	COG1902	pentaerythritol trinitrate reductase activity
BA6348_10725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA6348_10730	COG2211	Major facilitator Superfamily
BA6348_10740	COG1131	(ABC) transporter
BA6348_10745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BA6348_10765	COG1595	DNA-templated transcription, initiation
BA6348_10770	COG1061	Type III restriction enzyme res subunit
BA6348_10775	COG1253	flavin adenine dinucleotide binding
BA6348_10790	COG4120	Belongs to the binding-protein-dependent transport system permease family
BA6348_10795	COG1116	anion transmembrane transporter activity
BA6348_10795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BA6348_10800	COG2814	Major facilitator Superfamily
BA6348_10800	COG0477	Major facilitator Superfamily
BA6348_10805	COG4533	DNA binding
BA6348_10820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BA6348_10835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BA6348_10850	COG0835	chemotaxis
BA6348_10865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_10875	COG0861	Integral membrane protein TerC family
BA6348_10905	COG0210	DNA helicase
BA6348_10910	COG1253	flavin adenine dinucleotide binding
BA6348_10915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA6348_10920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA6348_10930	COG0613	PHP domain protein
BA6348_10945	COG2153	protein acetylation
BA6348_10950	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BA6348_10960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BA6348_11080	COG0745	RESPONSE REGULATOR receiver
BA6348_11085	COG5002	protein histidine kinase activity
BA6348_11095	COG0501	Belongs to the peptidase M48B family
BA6348_11120	COG1518	maintenance of DNA repeat elements
BA6348_11125	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BA6348_11135	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_11180	COG0697	spore germination
BA6348_11185	COG1522	sequence-specific DNA binding
BA6348_11200	COG0653	protein targeting
BA6348_11215	COG1231	oxidoreductase activity
BA6348_11230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA6348_11255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BA6348_11255	COG0456	acetyltransferase
BA6348_11265	COG0745	RESPONSE REGULATOR receiver
BA6348_11270	COG3850	Histidine kinase
BA6348_11270	COG5002	protein histidine kinase activity
BA6348_11280	COG3212	peptidase
BA6348_11285	COG1227	inorganic diphosphatase activity
BA6348_11290	COG0789	Transcriptional regulator
BA6348_11325	COG4372	Transposase
BA6348_11330	COG3876	Protein conserved in bacteria
BA6348_11370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_11375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_11380	COG1120	ATPase activity
BA6348_11390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA6348_11400	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA6348_11425	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BA6348_11465	COG1074	ATP-dependent DNA helicase activity
BA6348_11480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_11525	COG2962	Rard protein
BA6348_11530	COG0351	phosphomethylpyrimidine kinase
BA6348_11535	COG1136	(ABC) transporter
BA6348_11535	COG0577	efflux transmembrane transporter activity
BA6348_11540	COG0577	efflux transmembrane transporter activity
BA6348_11540	COG1136	(ABC) transporter
BA6348_11545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA6348_11555	COG4106	trans-aconitate 2-methyltransferase activity
BA6348_11570	COG2217	Heavy metal translocating P-type atpase
BA6348_11580	COG0716	FMN binding
BA6348_11585	COG2171	N-acyltransferase activity
BA6348_11590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA6348_11595	COG1473	amidohydrolase
BA6348_11610	COG1705	Flagellar rod assembly protein muramidase FlgJ
BA6348_11630	COG2267	carboxylic ester hydrolase activity
BA6348_11645	COG0167	dihydroorotate dehydrogenase activity
BA6348_11650	COG1982	Orn Lys Arg decarboxylase major
BA6348_11660	COG4493	Belongs to the UPF0637 family
BA6348_11685	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BA6348_11700	COG0386	Belongs to the glutathione peroxidase family
BA6348_11730	COG0626	cystathionine gamma-synthase activity
BA6348_11735	COG0626	cystathionine gamma-synthase activity
BA6348_11745	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BA6348_11770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA6348_11775	COG2843	Capsule synthesis protein
BA6348_11800	COG1393	Belongs to the ArsC family
BA6348_11805	COG1024	Enoyl-CoA hydratase
BA6348_11815	COG0454	-acetyltransferase
BA6348_11820	COG0439	Biotin carboxylase
BA6348_11825	COG0511	ligase activity, forming carbon-carbon bonds
BA6348_11830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA6348_11835	COG1024	Enoyl-CoA hydratase
BA6348_11840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BA6348_11850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BA6348_11865	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BA6348_11880	COG2807	transmembrane transport
BA6348_11885	COG2186	Transcriptional regulator
BA6348_11890	COG0531	amino acid
BA6348_11895	COG0583	DNA-binding transcription factor activity
BA6348_11900	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BA6348_11905	COG2001	Belongs to the MraZ family
BA6348_11910	COG0275	rRNA processing
BA6348_11925	COG0768	penicillin binding
BA6348_11935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA6348_11940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BA6348_11945	COG0772	Belongs to the SEDS family
BA6348_11950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA6348_11955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BA6348_11960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BA6348_11965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BA6348_11980	COG3856	small basic protein
BA6348_11990	COG0849	cell division
BA6348_11995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BA6348_12005	COG1191	sigma factor activity
BA6348_12010	COG1191	sigma factor activity
BA6348_12015	COG1873	PFAM PRC-barrel domain
BA6348_12025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BA6348_12030	COG1799	cell septum assembly
BA6348_12035	COG0762	integral membrane protein
BA6348_12040	COG2302	S4 RNA-binding domain
BA6348_12045	COG3599	regulation of cell shape
BA6348_12050	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BA6348_12060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BA6348_12065	COG4948	Mandelate Racemase Muconate Lactonizing
BA6348_12070	COG2814	Major facilitator Superfamily
BA6348_12075	COG0494	nUDIX hydrolase
BA6348_12080	COG0492	ferredoxin-NADP+ reductase activity
BA6348_12085	COG1316	TRANSCRIPTIONal
BA6348_12140	COG0551	DNA topoisomerase type I activity
BA6348_12140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA6348_12145	COG1842	Phage shock protein A
BA6348_12170	COG1543	Belongs to the glycosyl hydrolase 57 family
BA6348_12175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BA6348_12195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BA6348_12200	COG0564	pseudouridine synthase activity
BA6348_12215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BA6348_12225	COG0540	Belongs to the ATCase OTCase family
BA6348_12230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BA6348_12240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BA6348_12245	COG0284	orotidine-5'-phosphate decarboxylase activity
BA6348_12250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BA6348_12265	COG0640	Transcriptional regulator
BA6348_12275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA6348_12290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BA6348_12295	COG0673	inositol 2-dehydrogenase activity
BA6348_12300	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BA6348_12310	COG0460	homoserine dehydrogenase
BA6348_12315	COG2843	Capsule synthesis protein
BA6348_12325	COG0494	nUDIX hydrolase
BA6348_12330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BA6348_12340	COG4846	Membrane protein involved in cytochrome C biogenesis
BA6348_12355	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BA6348_12360	COG1547	Domain of unknown function (DUF309)
BA6348_12390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BA6348_12395	COG1024	Enoyl-CoA hydratase
BA6348_12425	COG1561	YicC-like family, N-terminal region
BA6348_12430	COG2052	Domain of unknown function (DUF370)
BA6348_12435	COG0194	GDP metabolic process
BA6348_12440	COG1758	RNA polymerase activity
BA6348_12445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA6348_12450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BA6348_12455	COG0242	peptide deformylase activity
BA6348_12460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BA6348_12465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BA6348_12465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA6348_12470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BA6348_12475	COG0631	protein serine/threonine phosphatase activity
BA6348_12480	COG2815	serine threonine protein kinase
BA6348_12480	COG0515	serine threonine protein kinase
BA6348_12490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BA6348_12495	COG1714	RDD family
BA6348_12505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA6348_12510	COG0765	amino acid transport
BA6348_12515	COG1126	abc transporter atp-binding protein
BA6348_12520	COG3859	Proton-coupled thiamine transporter YuaJ
BA6348_12530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BA6348_12535	COG1302	Protein conserved in bacteria
BA6348_12540	COG1461	Dihydroxyacetone kinase
BA6348_12545	COG1307	EDD domain protein, DegV family
BA6348_12550	COG1760	l-serine dehydratase
BA6348_12555	COG1760	l-serine dehydratase
BA6348_12560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BA6348_12580	COG3708	Transcriptional regulator
BA6348_12580	COG2207	Transcriptional regulator
BA6348_12585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA6348_12600	COG4990	cell redox homeostasis
BA6348_12630	COG1132	(ABC) transporter
BA6348_12635	COG3209	COG3209 Rhs family protein
BA6348_12640	COG0477	Major facilitator Superfamily
BA6348_12645	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BA6348_12655	COG0583	DNA-binding transcription factor activity
BA6348_12660	COG5522	Integral membrane protein (intg_mem_TP0381)
BA6348_12675	COG1027	Aspartate ammonia-lyase
BA6348_12690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA6348_12695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BA6348_12700	COG0438	transferase activity, transferring glycosyl groups
BA6348_12730	COG0714	Associated with various cellular activities
BA6348_12755	COG4632	Exopolysaccharide biosynthesis protein
BA6348_12755	COG5434	Belongs to the glycosyl hydrolase 28 family
BA6348_12760	COG0405	Gamma-glutamyltransferase
BA6348_12770	COG1876	peptidase activity
BA6348_12775	COG0681	Belongs to the peptidase S26 family
BA6348_12780	COG1846	Transcriptional regulator
BA6348_12790	COG2309	aminopeptidase activity
BA6348_12800	COG1755	Isoprenylcysteine carboxyl methyltransferase
BA6348_12805	COG3424	synthase
BA6348_12815	COG2211	Major facilitator Superfamily
BA6348_12820	COG5001	Diguanylate cyclase
BA6348_12820	COG3300	MHYT domain
BA6348_12830	COG0306	phosphate transporter
BA6348_12840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BA6348_12845	COG1793	dna ligase
BA6348_12845	COG3285	dna ligase
BA6348_12850	COG0697	spore germination
BA6348_12870	COG1793	dna ligase
BA6348_12885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BA6348_12890	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BA6348_12900	COG0742	ribosomal rna small subunit methyltransferase
BA6348_12905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BA6348_12910	COG3314	Sporulation integral membrane protein YlbJ
BA6348_12915	COG1752	Esterase of the alpha-beta hydrolase superfamily
BA6348_12920	COG3480	Lon protease (S16) C-terminal proteolytic domain
BA6348_12930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BA6348_12935	COG1349	DNA-binding transcription factor activity
BA6348_12960	COG4555	ABC transporter
BA6348_12965	COG1349	DNA-binding transcription factor activity
BA6348_12970	COG0416	fatty acid biosynthetic process
BA6348_12975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA6348_12980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BA6348_12985	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_12990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BA6348_12995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BA6348_13005	COG1196	nuclear chromosome segregation
BA6348_13010	COG0552	protein localization to endoplasmic reticulum
BA6348_13015	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BA6348_13020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BA6348_13025	COG0228	four-way junction DNA binding
BA6348_13030	COG1837	Belongs to the UPF0109 family
BA6348_13045	COG0336	Belongs to the RNA methyltransferase TrmD family
BA6348_13050	COG0335	large ribosomal subunit rRNA binding
BA6348_13055	COG0681	Belongs to the peptidase S26 family
BA6348_13065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BA6348_13075	COG2257	FlhB HrpN YscU SpaS Family
BA6348_13090	COG3541	Predicted nucleotidyltransferase
BA6348_13105	COG0606	chelatase, subunit chli
BA6348_13115	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BA6348_13125	COG3706	GGDEF domain
BA6348_13130	COG0393	Putative heavy-metal-binding
BA6348_13150	COG0045	succinate-CoA ligase (ADP-forming) activity
BA6348_13155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BA6348_13160	COG0758	DNA mediated transformation
BA6348_13165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA6348_13170	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BA6348_13175	COG4974	Belongs to the 'phage' integrase family
BA6348_13180	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BA6348_13185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BA6348_13190	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BA6348_13195	COG1815	bacterial-type flagellum-dependent cell motility
BA6348_13200	COG1558	bacterial-type flagellum-dependent cell motility
BA6348_13205	COG1677	Flagellar hook-basal body complex protein FliE
BA6348_13210	COG1766	The M ring may be actively involved in energy transduction
BA6348_13215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA6348_13225	COG1157	protein secretion by the type III secretion system
BA6348_13250	COG4786	Flagellar basal body rod
BA6348_13265	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA6348_13270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA6348_13270	COG1776	CheC inhibitor of MCP methylation
BA6348_13275	COG2201	protein-glutamate methylesterase activity
BA6348_13280	COG3190	flagellar
BA6348_13285	COG1338	Plays a role in the flagellum-specific transport system
BA6348_13290	COG1987	bacterial-type flagellum assembly
BA6348_13295	COG1684	flagellar biosynthetic protein fliR
BA6348_13300	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BA6348_13305	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BA6348_13310	COG1419	protein localization to endoplasmic reticulum
BA6348_13315	COG0455	bacterial-type flagellum organization
BA6348_13320	COG2201	protein-glutamate methylesterase activity
BA6348_13325	COG0643	Histidine kinase
BA6348_13325	COG2198	Histidine kinase
BA6348_13330	COG0835	chemotaxis
BA6348_13335	COG1776	CheC inhibitor of MCP methylation
BA6348_13340	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BA6348_13350	COG1191	sigma factor activity
BA6348_13375	COG0052	Belongs to the universal ribosomal protein uS2 family
BA6348_13380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BA6348_13385	COG0528	UMP kinase activity
BA6348_13390	COG0233	cytoplasmic translational termination
BA6348_13395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BA6348_13400	COG4589	Belongs to the CDS family
BA6348_13405	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BA6348_13410	COG0750	zinc metalloprotease
BA6348_13415	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BA6348_13420	COG0442	prolyl-tRNA aminoacylation
BA6348_13425	COG2176	DNA-directed DNA polymerase activity
BA6348_13430	COG0779	Required for maturation of 30S ribosomal subunits
BA6348_13435	COG0195	Participates in both transcription termination and antitermination
BA6348_13445	COG1358	cellular component organization or biogenesis
BA6348_13450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BA6348_13450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BA6348_13460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BA6348_13465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BA6348_13470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BA6348_13475	COG0196	riboflavin kinase activity
BA6348_13480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BA6348_13485	COG1185	polyribonucleotide nucleotidyltransferase activity
BA6348_13490	COG0726	polysaccharide deacetylase
BA6348_13495	COG0612	Peptidase, M16
BA6348_13505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA6348_13510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA6348_13515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA6348_13520	COG0527	aspartate kinase activity
BA6348_13525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA6348_13530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BA6348_13535	COG0740	serine-type endopeptidase activity
BA6348_13545	COG4980	gas vesicle protein
BA6348_13545	COG1674	ftsk spoiiie
BA6348_13550	COG2188	Transcriptional regulator
BA6348_13575	COG0739	heme binding
BA6348_13580	COG0612	Peptidase, M16
BA6348_13585	COG0612	Peptidase, M16
BA6348_13590	COG0300	oxidoreductase activity
BA6348_13605	COG1426	Protein conserved in bacteria
BA6348_13610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BA6348_13615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BA6348_13625	COG0513	Belongs to the DEAD box helicase family
BA6348_13630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BA6348_13635	COG2137	regulation of response to DNA damage stimulus
BA6348_13645	COG1692	metallophosphoesterase
BA6348_13650	COG2359	stage V sporulation protein S
BA6348_13660	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BA6348_13660	COG0674	pyruvate-flavodoxin oxidoreductase activity
BA6348_13665	COG1013	pyruvate-flavodoxin oxidoreductase activity
BA6348_13670	COG3949	Membrane
BA6348_13675	COG1234	tRNA 3'-trailer cleavage
BA6348_13680	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BA6348_13690	COG0517	IMP dehydrogenase activity
BA6348_13700	COG0095	Lipoate-protein ligase
BA6348_13705	COG3693	PFAM glycoside hydrolase, family 10
BA6348_13710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BA6348_13715	COG4550	Control of competence regulator ComK, YlbF/YmcA
BA6348_13730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BA6348_13735	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BA6348_13740	COG2521	methyltransferase
BA6348_13740	COG2136	Putative SAM-dependent methyltransferase
BA6348_13745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BA6348_13750	COG1923	regulation of RNA biosynthetic process
BA6348_13780	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BA6348_13785	COG2814	Major facilitator Superfamily
BA6348_13795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BA6348_13805	COG0464	growth
BA6348_13815	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BA6348_13820	COG0789	Transcriptional regulator
BA6348_13825	COG0174	glutamine synthetase
BA6348_13835	COG0789	Transcriptional regulator
BA6348_13870	COG5566	PFAM Mor transcription activator
BA6348_13885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BA6348_13890	COG3942	CHAP domain
BA6348_13890	COG1388	LysM domain
BA6348_13895	COG4224	UPF0291 protein
BA6348_13900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BA6348_13905	COG3973	AAA domain
BA6348_13910	COG0316	Belongs to the HesB IscA family
BA6348_13940	COG0022	dehydrogenase e1 component
BA6348_13945	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA6348_13975	COG0488	(ABC) transporter
BA6348_13985	COG5434	Belongs to the glycosyl hydrolase 28 family
BA6348_13985	COG4632	Exopolysaccharide biosynthesis protein
BA6348_13995	COG0833	amino acid
BA6348_14000	COG0515	serine threonine protein kinase
BA6348_14010	COG4848	Belongs to the UPF0354 family
BA6348_14035	COG2707	UPF0756 membrane protein
BA6348_14045	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_14055	COG3773	Cell wall hydrolase
BA6348_14055	COG3409	Peptidoglycan-binding domain 1 protein
BA6348_14065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA6348_14070	COG0626	cystathionine gamma-synthase activity
BA6348_14075	COG1595	DNA-templated transcription, initiation
BA6348_14090	COG1131	(ABC) transporter
BA6348_14100	COG5002	protein histidine kinase activity
BA6348_14115	COG0187	DNA topoisomerase II activity
BA6348_14120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BA6348_14135	COG0778	Nitroreductase
BA6348_14140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BA6348_14145	COG0673	inositol 2-dehydrogenase activity
BA6348_14155	COG1846	Transcriptional regulator
BA6348_14160	COG2814	Major facilitator Superfamily
BA6348_14165	COG0464	growth
BA6348_14175	COG3835	regulator
BA6348_14180	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_14185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA6348_14190	COG1694	Mazg nucleotide pyrophosphohydrolase
BA6348_14195	COG1611	Belongs to the LOG family
BA6348_14220	COG0493	'glutamate synthase
BA6348_14225	COG0167	dihydroorotate dehydrogenase activity
BA6348_14250	COG1953	Uracil, thiamine, allantoin
BA6348_14255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BA6348_14260	COG3290	protein histidine kinase activity
BA6348_14265	COG4565	transcriptional regulatory protein
BA6348_14300	COG0352	thiamine-phosphate diphosphorylase activity
BA6348_14305	COG0352	thiamine-phosphate diphosphorylase activity
BA6348_14320	COG3852	Histidine kinase
BA6348_14330	COG2197	response regulator
BA6348_14335	COG4585	Histidine kinase
BA6348_14355	COG0785	Cytochrome C biogenesis protein
BA6348_14360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA6348_14370	COG3093	addiction module antidote protein HigA
BA6348_14420	COG2207	Transcriptional regulator
BA6348_14470	COG1956	GAF domain-containing protein
BA6348_14475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA6348_14525	COG0385	Bile acid
BA6348_14575	COG0482	sulfurtransferase activity
BA6348_14590	COG2819	hydrolase of the alpha beta superfamily
BA6348_14595	COG1780	Probably involved in ribonucleotide reductase function
BA6348_14600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA6348_14605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA6348_14610	COG1114	Component of the transport system for branched-chain amino acids
BA6348_14615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BA6348_14620	COG1607	acyl-coa hydrolase
BA6348_14635	COG2843	Capsule synthesis protein
BA6348_14645	COG0318	PFAM AMP-dependent synthetase and ligase
BA6348_14665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA6348_14670	COG1388	LysM domain
BA6348_14670	COG3858	chitin binding
BA6348_14685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA6348_14695	COG2104	thiamine diphosphate biosynthetic process
BA6348_14700	COG2022	thiamine diphosphate biosynthetic process
BA6348_14705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA6348_14710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BA6348_14715	COG1116	anion transmembrane transporter activity
BA6348_14720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BA6348_14725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BA6348_14730	COG0640	Transcriptional regulator
BA6348_14735	COG5658	integral membrane protein
BA6348_14750	COG1131	(ABC) transporter
BA6348_14780	COG2027	D-alanyl-D-alanine carboxypeptidase
BA6348_14785	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BA6348_14800	COG1114	Component of the transport system for branched-chain amino acids
BA6348_14805	COG0697	spore germination
BA6348_14815	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BA6348_14820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BA6348_14830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BA6348_14830	COG0069	glutamate synthase activity
BA6348_14835	COG3361	conserved protein (COG2071)
BA6348_14850	COG0697	spore germination
BA6348_14860	COG0242	peptide deformylase activity
BA6348_14870	COG2340	Cysteine-rich secretory protein family
BA6348_14880	COG1278	Cold shock
BA6348_14905	COG0753	catalase activity
BA6348_14950	COG4989	oxidoreductase activity
BA6348_14955	COG3604	Transcriptional regulator
BA6348_14980	COG0069	glutamate synthase activity
BA6348_14980	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BA6348_14990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_14990	COG2207	Transcriptional regulator
BA6348_14995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_15030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BA6348_15030	COG0300	oxidoreductase activity
BA6348_15030	COG3321	synthase
BA6348_15030	COG4221	oxidoreductase activity
BA6348_15045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BA6348_15050	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BA6348_15075	COG0673	inositol 2-dehydrogenase activity
BA6348_15095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BA6348_15110	COG0250	Participates in transcription elongation, termination and antitermination
BA6348_15135	COG1132	(ABC) transporter
BA6348_15140	COG1132	(ABC) transporter
BA6348_15160	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BA6348_15180	COG0813	purine-nucleoside phosphorylase activity
BA6348_15195	COG1686	Belongs to the peptidase S11 family
BA6348_15200	COG2357	RelA SpoT domain protein
BA6348_15205	COG0739	heme binding
BA6348_15205	COG1196	nuclear chromosome segregation
BA6348_15205	COG0741	lytic transglycosylase activity
BA6348_15220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA6348_15240	COG0714	Associated with various cellular activities
BA6348_15245	COG3069	C4-dicarboxylate transmembrane transporter activity
BA6348_15255	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_15265	COG3949	Membrane
BA6348_15275	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BA6348_15310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_15315	COG1475	DNA binding
BA6348_15320	COG0019	diaminopimelate decarboxylase activity
BA6348_15330	COG4264	IucA IucC family
BA6348_15335	COG4264	IucA IucC family
BA6348_15340	COG2814	Major facilitator Superfamily
BA6348_15345	COG4264	IucA IucC family
BA6348_15350	COG2423	ornithine cyclodeaminase activity
BA6348_15375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BA6348_15380	COG2200	EAL domain
BA6348_15385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA6348_15390	COG0798	PFAM Bile acid sodium symporter
BA6348_15395	COG0346	lactoylglutathione lyase activity
BA6348_15400	COG0640	Transcriptional regulator
BA6348_15425	COG1653	transport
BA6348_15435	COG1082	Xylose isomerase domain protein TIM barrel
BA6348_15445	COG5002	protein histidine kinase activity
BA6348_15455	COG1063	alcohol dehydrogenase
BA6348_15460	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_15470	COG0784	Response regulator, receiver
BA6348_15490	COG1115	amino acid carrier protein
BA6348_15515	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BA6348_15520	COG1737	Transcriptional regulator
BA6348_15525	COG1070	Carbohydrate kinase
BA6348_15550	COG0069	glutamate synthase activity
BA6348_15550	COG0070	glutamate synthase
BA6348_15550	COG0067	glutamate synthase
BA6348_15555	COG0583	DNA-binding transcription factor activity
BA6348_15560	COG0456	acetyltransferase
BA6348_15560	COG0454	-acetyltransferase
BA6348_15565	COG1464	Belongs to the NlpA lipoprotein family
BA6348_15570	COG2011	ABC-type metal ion transport system permease component
BA6348_15575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BA6348_15590	COG1464	Belongs to the NlpA lipoprotein family
BA6348_15595	COG2011	ABC-type metal ion transport system permease component
BA6348_15600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BA6348_15605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BA6348_15610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA6348_15615	COG0456	acetyltransferase
BA6348_15615	COG1214	PFAM Peptidase M22, glycoprotease
BA6348_15620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA6348_15625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BA6348_15630	COG2826	transposase and inactivated derivatives, IS30 family
BA6348_15645	COG3483	tryptophan 2,3-dioxygenase activity
BA6348_15650	COG0402	S-adenosylhomocysteine deaminase activity
BA6348_15655	COG0586	Pfam SNARE associated Golgi protein
BA6348_15660	COG0490	domain, Protein
BA6348_15665	COG0475	glutathione-regulated potassium exporter activity
BA6348_15725	COG0439	Biotin carboxylase
BA6348_15730	COG0511	ligase activity, forming carbon-carbon bonds
BA6348_15735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BA6348_15745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BA6348_15745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BA6348_15755	COG0511	ligase activity, forming carbon-carbon bonds
BA6348_15760	COG1309	transcriptional regulator
BA6348_15765	COG1876	peptidase activity
BA6348_15770	COG0385	Bile acid
BA6348_15780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA6348_15780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA6348_15785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA6348_15790	COG1506	peptidase
BA6348_15790	COG4946	Tricorn protease homolog
BA6348_15790	COG0823	Involved in the tonB-independent uptake of proteins
BA6348_15795	COG0823	Involved in the tonB-independent uptake of proteins
BA6348_15795	COG1506	peptidase
BA6348_15800	COG4166	transmembrane transport
BA6348_15805	COG4608	Belongs to the ABC transporter superfamily
BA6348_15810	COG0444	Belongs to the ABC transporter superfamily
BA6348_15815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_15820	COG0601	transmembrane transport
BA6348_15830	COG0697	spore germination
BA6348_15835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA6348_15840	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BA6348_15840	COG2755	lipolytic protein G-D-S-L family
BA6348_15860	COG1199	ATP-dependent helicase activity
BA6348_15875	COG1164	Oligoendopeptidase f
BA6348_15880	COG2309	aminopeptidase activity
BA6348_15890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BA6348_15895	COG1984	allophanate hydrolase subunit 2
BA6348_15900	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BA6348_15905	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BA6348_15910	COG1414	Transcriptional regulator
BA6348_15930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA6348_15945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA6348_15950	COG5002	protein histidine kinase activity
BA6348_15985	COG5002	protein histidine kinase activity
BA6348_15990	COG0745	RESPONSE REGULATOR receiver
BA6348_16000	COG3708	Transcriptional regulator
BA6348_16010	COG2378	regulation of single-species biofilm formation
BA6348_16020	COG4302	ethanolamine ammonia-lyase activity
BA6348_16040	COG1959	2 iron, 2 sulfur cluster binding
BA6348_16055	COG0537	adenosine 5'-monophosphoramidase activity
BA6348_16060	COG0492	ferredoxin-NADP+ reductase activity
BA6348_16065	COG3858	chitin binding
BA6348_16080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA6348_16100	COG3546	catalase activity
BA6348_16110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA6348_16115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA6348_16135	COG2720	vancomycin resistance protein
BA6348_16145	COG0574	Belongs to the PEP-utilizing enzyme family
BA6348_16145	COG3848	Pyruvate phosphate dikinase
BA6348_16160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_16160	COG2207	Transcriptional regulator
BA6348_16195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA6348_16205	COG4684	Psort location CytoplasmicMembrane, score
BA6348_16210	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BA6348_16215	COG1122	ATPase activity
BA6348_16220	COG1122	ATPase activity
BA6348_16225	COG3829	transcription factor binding
BA6348_16225	COG3290	protein histidine kinase activity
BA6348_16240	COG0456	acetyltransferase
BA6348_16245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA6348_16245	COG3153	acetyltransferase
BA6348_16260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA6348_16270	COG2508	Transcriptional regulator
BA6348_16280	COG0488	(ABC) transporter
BA6348_16290	COG4208	sulfate ABC transporter
BA6348_16300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BA6348_16320	COG0756	dUTP diphosphatase activity
BA6348_16340	COG0546	phosphoglycolate phosphatase activity
BA6348_16345	COG0154	amidase activity
BA6348_16370	COG0456	acetyltransferase
BA6348_16400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA6348_16410	COG0564	pseudouridine synthase activity
BA6348_16415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA6348_16420	COG0583	DNA-binding transcription factor activity
BA6348_16425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BA6348_16430	COG0066	3-isopropylmalate dehydratase activity
BA6348_16440	COG0318	PFAM AMP-dependent synthetase and ligase
BA6348_16450	COG1666	GTP binding
BA6348_16455	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_16470	COG1164	Oligoendopeptidase f
BA6348_16475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BA6348_16480	COG0438	transferase activity, transferring glycosyl groups
BA6348_16485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA6348_16490	COG0463	Glycosyl transferase, family 2
BA6348_16500	COG0438	transferase activity, transferring glycosyl groups
BA6348_16510	COG3935	DnaD domain protein
BA6348_16515	COG0017	Asparaginyl-tRNA synthetase
BA6348_16530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA6348_16550	COG0402	S-adenosylhomocysteine deaminase activity
BA6348_16555	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BA6348_16565	COG1199	ATP-dependent helicase activity
BA6348_16565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BA6348_16575	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BA6348_16580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BA6348_16585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BA6348_16590	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BA6348_16590	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BA6348_16595	COG0617	tRNA 3'-terminal CCA addition
BA6348_16600	COG0438	transferase activity, transferring glycosyl groups
BA6348_16605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BA6348_16610	COG1803	Methylglyoxal synthase
BA6348_16615	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BA6348_16620	COG1694	Mazg nucleotide pyrophosphohydrolase
BA6348_16625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA6348_16645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BA6348_16680	COG1595	DNA-templated transcription, initiation
BA6348_16690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BA6348_16695	COG0287	Prephenate dehydrogenase
BA6348_16700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA6348_16705	COG0159	tryptophan synthase activity
BA6348_16710	COG0133	tryptophan synthase activity
BA6348_16715	COG0135	phosphoribosylanthranilate isomerase activity
BA6348_16720	COG0134	indole-3-glycerol-phosphate synthase activity
BA6348_16725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BA6348_16740	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BA6348_16745	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BA6348_16750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BA6348_16755	COG0105	UTP biosynthetic process
BA6348_16760	COG0142	geranyltranstransferase activity
BA6348_16775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BA6348_16785	COG0142	geranyltranstransferase activity
BA6348_16800	COG0741	lytic transglycosylase activity
BA6348_16810	COG0302	gtp cyclohydrolase
BA6348_16815	COG0776	regulation of translation
BA6348_16820	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BA6348_16855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BA6348_16860	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BA6348_16865	COG1160	GTP binding
BA6348_16885	COG1304	FMN binding
BA6348_16890	COG0539	negative regulation of cytoplasmic translation
BA6348_16915	COG2959	enzyme of heme biosynthesis
BA6348_16920	COG3773	Cell wall hydrolase
BA6348_16920	COG3409	Peptidoglycan-binding domain 1 protein
BA6348_16925	COG2339	peptidase activity
BA6348_16935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BA6348_16940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BA6348_16945	COG4862	establishment of competence for transformation
BA6348_16960	COG1388	LysM domain
BA6348_16970	COG0514	ATP-dependent DNA helicase (RecQ)
BA6348_16985	COG1141	Ferredoxin
BA6348_16990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BA6348_16995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA6348_17000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BA6348_17010	COG0546	phosphoglycolate phosphatase activity
BA6348_17015	COG5002	protein histidine kinase activity
BA6348_17020	COG0745	RESPONSE REGULATOR receiver
BA6348_17025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA6348_17030	COG1333	cytochrome c biogenesis protein
BA6348_17035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA6348_17040	COG1187	pseudouridine synthase activity
BA6348_17045	COG0700	Nucleoside recognition
BA6348_17050	COG2715	membrane protein required for spore maturation
BA6348_17055	COG1686	Belongs to the peptidase S11 family
BA6348_17060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BA6348_17065	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BA6348_17070	COG1994	Peptidase M50
BA6348_17075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA6348_17080	COG3287	FIST C domain
BA6348_17080	COG2199	diguanylate cyclase activity
BA6348_17080	COG2200	EAL domain
BA6348_17085	COG0019	diaminopimelate decarboxylase activity
BA6348_17090	COG0697	spore germination
BA6348_17105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA6348_17130	COG2172	sigma factor antagonist activity
BA6348_17140	COG1686	Belongs to the peptidase S11 family
BA6348_17145	COG0840	transmembrane signaling receptor activity
BA6348_17150	COG4608	Belongs to the ABC transporter superfamily
BA6348_17155	COG0444	Belongs to the ABC transporter superfamily
BA6348_17160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_17165	COG0601	transmembrane transport
BA6348_17170	COG4166	transmembrane transport
BA6348_17190	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BA6348_17195	COG4974	Belongs to the 'phage' integrase family
BA6348_17205	COG0686	Belongs to the AlaDH PNT family
BA6348_17210	COG0735	belongs to the Fur family
BA6348_17215	COG1300	Membrane
BA6348_17220	COG1379	DNA repair
BA6348_17240	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA6348_17245	COG0346	lactoylglutathione lyase activity
BA6348_17255	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA6348_17260	COG0022	dehydrogenase e1 component
BA6348_17265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BA6348_17270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA6348_17275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BA6348_17280	COG3829	transcription factor binding
BA6348_17280	COG3290	protein histidine kinase activity
BA6348_17315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA6348_17325	COG2226	methyltransferase
BA6348_17335	COG1408	metallophosphoesterase
BA6348_17340	COG0288	reversible hydration of carbon dioxide
BA6348_17350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA6348_17360	COG0750	zinc metalloprotease
BA6348_17365	COG0497	DNA recombination
BA6348_17370	COG1438	arginine binding
BA6348_17375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BA6348_17380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BA6348_17385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BA6348_17405	COG1570	exodeoxyribonuclease VII activity
BA6348_17410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BA6348_17420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BA6348_17435	COG1302	Protein conserved in bacteria
BA6348_17440	COG0439	Biotin carboxylase
BA6348_17445	COG0511	ligase activity, forming carbon-carbon bonds
BA6348_17485	COG3854	ATPases associated with a variety of cellular activities
BA6348_17500	COG1809	phosphosulfolactate synthase activity
BA6348_17505	COG2045	Belongs to the ComB family
BA6348_17510	COG2707	UPF0756 membrane protein
BA6348_17515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BA6348_17520	COG0006	proline dipeptidase activity
BA6348_17525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BA6348_17535	COG3872	metal-dependent enzyme
BA6348_17545	COG1752	Esterase of the alpha-beta hydrolase superfamily
BA6348_17550	COG1321	iron dependent repressor
BA6348_17555	COG0431	NADPH-dependent FMN reductase
BA6348_17565	COG5002	protein histidine kinase activity
BA6348_17575	COG2234	aminopeptidase activity
BA6348_17585	COG0095	Lipoate-protein ligase
BA6348_17590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA6348_17595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BA6348_17600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BA6348_17610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA6348_17635	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BA6348_17650	COG1910	domain protein
BA6348_17655	COG0725	ABC transporter, periplasmic molybdate-binding protein
BA6348_17660	COG4149	molybdate abc transporter
BA6348_17665	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BA6348_17670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BA6348_17685	COG3679	Belongs to the UPF0342 family
BA6348_17710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BA6348_17715	COG3546	catalase activity
BA6348_17730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA6348_17735	COG0191	fructose-bisphosphate aldolase activity
BA6348_17740	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_17750	COG3775	system Galactitol-specific IIC component
BA6348_17770	COG3279	Response regulator of the LytR AlgR family
BA6348_17775	COG1525	nuclease
BA6348_17790	COG0789	Transcriptional regulator
BA6348_17795	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BA6348_17805	COG0772	Belongs to the SEDS family
BA6348_17815	COG0028	Belongs to the TPP enzyme family
BA6348_17820	COG3773	Cell wall hydrolase
BA6348_17820	COG3409	Peptidoglycan-binding domain 1 protein
BA6348_17835	COG0733	neurotransmitter:sodium symporter activity
BA6348_17840	COG4838	Belongs to the UPF0358 family
BA6348_17845	COG2066	Belongs to the glutaminase family
BA6348_17850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BA6348_17855	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BA6348_17860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BA6348_17870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA6348_17875	COG3829	transcription factor binding
BA6348_17880	COG0833	amino acid
BA6348_17885	COG0477	Major facilitator Superfamily
BA6348_17890	COG0583	DNA-binding transcription factor activity
BA6348_17895	COG0671	phosphoesterase, PA-phosphatase related
BA6348_17900	COG1671	Belongs to the UPF0178 family
BA6348_17910	COG1404	Belongs to the peptidase S8 family
BA6348_17930	COG1234	tRNA 3'-trailer cleavage
BA6348_17935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BA6348_17940	COG1116	anion transmembrane transporter activity
BA6348_17945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BA6348_17950	COG0346	lactoylglutathione lyase activity
BA6348_17985	COG3739	integral membrane protein
BA6348_17990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_17990	COG2207	Transcriptional regulator
BA6348_17995	COG0604	alcohol dehydrogenase
BA6348_18000	COG0640	Transcriptional regulator
BA6348_18040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BA6348_18045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BA6348_18060	COG0646	methionine synthase
BA6348_18060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BA6348_18065	COG1410	methionine synthase
BA6348_18065	COG0646	methionine synthase
BA6348_18090	COG0018	arginyl-trna synthetase
BA6348_18100	COG0183	Belongs to the thiolase family
BA6348_18105	COG1126	abc transporter atp-binding protein
BA6348_18110	COG0765	amino acid transport
BA6348_18115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA6348_18120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BA6348_18125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BA6348_18140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BA6348_18165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BA6348_18165	COG2199	diguanylate cyclase activity
BA6348_18170	COG0303	'Molybdopterin
BA6348_18175	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BA6348_18180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BA6348_18185	COG5609	conserved protein (DUF2294)
BA6348_18195	COG2427	Protein of unknown function (DUF1641)
BA6348_18200	COG3383	formate dehydrogenase (NAD+) activity
BA6348_18205	COG1294	oxidase, subunit
BA6348_18210	COG1271	oxidase subunit
BA6348_18240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA6348_18245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA6348_18250	COG3162	membrane
BA6348_18255	COG3279	Response regulator of the LytR AlgR family
BA6348_18260	COG3275	phosphorelay sensor kinase activity
BA6348_18265	COG0367	asparagine synthase
BA6348_18275	COG0243	molybdopterin cofactor binding
BA6348_18290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BA6348_18295	COG0456	acetyltransferase
BA6348_18305	COG0535	radical SAM domain protein
BA6348_18315	COG0477	Major facilitator Superfamily
BA6348_18325	COG3942	CHAP domain
BA6348_18325	COG1388	LysM domain
BA6348_18335	COG3550	peptidyl-serine autophosphorylation
BA6348_18355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA6348_18365	COG1119	ATPase activity
BA6348_18390	COG4294	response to UV
BA6348_18400	COG2986	histidine ammonia-lyase
BA6348_18405	COG3011	Protein conserved in bacteria
BA6348_18410	COG0667	Aldo Keto reductase
BA6348_18430	COG2154	pterin-4-alpha-carbinolamine dehydratase
BA6348_18440	COG1428	Deoxynucleoside kinase
BA6348_18445	COG1428	Deoxynucleoside kinase
BA6348_18460	COG1595	DNA-templated transcription, initiation
BA6348_18470	COG0351	phosphomethylpyrimidine kinase
BA6348_18475	COG3850	Histidine kinase
BA6348_18480	COG2197	response regulator
BA6348_18500	COG0701	Predicted permease
BA6348_18510	COG2072	flavoprotein involved in K transport
BA6348_18520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA6348_18525	COG1408	metallophosphoesterase
BA6348_18530	COG3835	regulator
BA6348_18535	COG3842	ATPase activity
BA6348_18540	COG0561	phosphatase activity
BA6348_18545	COG2860	membrane
BA6348_18555	COG2249	NAD(P)H dehydrogenase (quinone) activity
BA6348_18575	COG1309	transcriptional regulator
BA6348_18595	COG3876	Protein conserved in bacteria
BA6348_18600	COG0318	PFAM AMP-dependent synthetase and ligase
BA6348_18610	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_18615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA6348_18620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BA6348_18625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BA6348_18630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA6348_18640	COG0456	acetyltransferase
BA6348_18645	COG0584	glycerophosphoryl diester phosphodiesterase
BA6348_18650	COG1242	4 iron, 4 sulfur cluster binding
BA6348_18715	COG3568	Endonuclease Exonuclease Phosphatase
BA6348_18725	COG0793	Belongs to the peptidase S41A family
BA6348_18725	COG3409	Peptidoglycan-binding domain 1 protein
BA6348_18735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BA6348_18740	COG2384	SAM-dependent methyltransferase
BA6348_18745	COG1960	acyl-CoA dehydrogenase activity
BA6348_18755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BA6348_18760	COG0358	DNA primase activity
BA6348_18765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BA6348_18770	COG0517	IMP dehydrogenase activity
BA6348_18775	COG0751	glycine-tRNA ligase activity
BA6348_18780	COG0752	glycyl-tRNA synthetase alpha subunit
BA6348_18785	COG1381	Involved in DNA repair and RecF pathway recombination
BA6348_18795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BA6348_18810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BA6348_18815	COG1702	phosphate starvation-inducible protein PhoH
BA6348_18840	COG4864	UPF0365 protein
BA6348_18845	COG1030	water channel activity
BA6348_18850	COG1610	YqeY-like protein
BA6348_18855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BA6348_18860	COG0537	adenosine 5'-monophosphoramidase activity
BA6348_18865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BA6348_18870	COG1181	Belongs to the D-alanine--D-alanine ligase family
BA6348_18885	COG1283	sodium-dependent phosphate transmembrane transporter activity
BA6348_18890	COG1346	cytolysis
BA6348_18895	COG1380	Effector of murein hydrolase LrgA
BA6348_18900	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BA6348_18910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BA6348_18915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BA6348_18920	COG2264	protein methyltransferase activity
BA6348_18930	COG0443	Heat shock 70 kDa protein
BA6348_18940	COG1420	regulation of RNA biosynthetic process
BA6348_18945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA6348_18950	COG0481	GTPase activity
BA6348_18955	COG0537	adenosine 5'-monophosphoramidase activity
BA6348_18960	COG0456	acetyltransferase
BA6348_18975	COG2226	methyltransferase
BA6348_18980	COG1120	ATPase activity
BA6348_18985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_18995	COG0006	proline dipeptidase activity
BA6348_19000	COG0596	Alpha beta hydrolase
BA6348_19015	COG0747	negative chemotaxis
BA6348_19020	COG4608	Belongs to the ABC transporter superfamily
BA6348_19025	COG0444	Belongs to the ABC transporter superfamily
BA6348_19035	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA6348_19045	COG0268	Binds directly to 16S ribosomal RNA
BA6348_19050	COG1466	dna polymerase III delta subunit
BA6348_19065	COG2333	competence protein COMEC
BA6348_19065	COG0658	competence protein
BA6348_19070	COG0367	asparagine synthase
BA6348_19075	COG1555	photosystem II stabilization
BA6348_19075	COG1596	polysaccharide export
BA6348_19080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA6348_19085	COG0495	leucyl-tRNA aminoacylation
BA6348_19090	COG2226	methyltransferase
BA6348_19095	COG0799	negative regulation of ribosome biogenesis
BA6348_19100	COG1713	HD superfamily hydrolase involved in NAD metabolism
BA6348_19105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BA6348_19110	COG1534	Rna-binding protein
BA6348_19115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BA6348_19120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BA6348_19125	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BA6348_19130	COG1309	transcriptional regulator
BA6348_19145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA6348_19150	COG0450	alkyl hydroperoxide reductase
BA6348_19155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BA6348_19160	COG4166	transmembrane transport
BA6348_19180	COG1413	lyase activity
BA6348_19205	COG1376	ErfK ybiS ycfS ynhG family protein
BA6348_19215	COG0488	(ABC) transporter
BA6348_19220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BA6348_19235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BA6348_19240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA6348_19245	COG3336	cytochrome c oxidase
BA6348_19250	COG1999	signal sequence binding
BA6348_19275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BA6348_19280	COG2843	Capsule synthesis protein
BA6348_19290	COG1329	Transcriptional regulator
BA6348_19325	COG1191	sigma factor activity
BA6348_19330	COG2201	protein-glutamate methylesterase activity
BA6348_19355	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BA6348_19355	COG2199	diguanylate cyclase activity
BA6348_19360	COG4974	Belongs to the 'phage' integrase family
BA6348_19390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BA6348_19390	COG2199	diguanylate cyclase activity
BA6348_19400	COG0768	penicillin binding
BA6348_19405	COG0572	uridine kinase
BA6348_19415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BA6348_19425	COG2610	gluconate transmembrane transporter activity
BA6348_19450	COG3906	Belongs to the UPF0473 family
BA6348_19455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BA6348_19460	COG4472	Bacterial protein of unknown function (DUF965)
BA6348_19465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA6348_19475	COG0628	permease
BA6348_19480	COG0861	Integral membrane protein TerC family
BA6348_19500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BA6348_19505	COG0840	transmembrane signaling receptor activity
BA6348_19515	COG1104	cysteine desulfurase activity
BA6348_19520	COG1959	2 iron, 2 sulfur cluster binding
BA6348_19530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BA6348_19540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BA6348_19545	COG0124	histidyl-tRNA synthetase
BA6348_19550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA6348_19555	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA6348_19565	COG1490	D-aminoacyl-tRNA deacylase activity
BA6348_19570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA6348_19575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BA6348_19580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BA6348_19580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BA6348_19585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BA6348_19590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA6348_19590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA6348_19595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA6348_19595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA6348_19605	COG2244	polysaccharide biosynthetic process
BA6348_19610	COG2323	membrane
BA6348_19615	COG0598	Magnesium transport protein CorA
BA6348_19625	COG1862	Preprotein translocase
BA6348_19635	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BA6348_19640	COG2247	cell wall binding repeat
BA6348_19640	COG2385	sporulation resulting in formation of a cellular spore
BA6348_19650	COG2255	four-way junction helicase activity
BA6348_19655	COG0632	four-way junction helicase activity
BA6348_19660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BA6348_19680	COG0737	Belongs to the 5'-nucleotidase family
BA6348_19690	COG1388	LysM domain
BA6348_19695	COG0077	Prephenate dehydratase
BA6348_19700	COG0083	homoserine kinase activity
BA6348_19705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BA6348_19710	COG0460	homoserine dehydrogenase
BA6348_19715	COG4492	Belongs to the UPF0735 family
BA6348_19720	COG1252	NADH dehydrogenase
BA6348_19735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BA6348_19745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BA6348_19755	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BA6348_19760	COG1530	ribonuclease E activity
BA6348_19765	COG1994	Peptidase M50
BA6348_19775	COG1278	Cold shock
BA6348_19780	COG0772	Belongs to the SEDS family
BA6348_19785	COG2894	cell division
BA6348_19800	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BA6348_19805	COG1792	Involved in formation and maintenance of cell shape
BA6348_19810	COG1077	Cell shape determining protein MreB Mrl
BA6348_19815	COG2003	Belongs to the UPF0758 family
BA6348_19820	COG0424	maF-like protein
BA6348_19835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA6348_19840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BA6348_19845	COG0285	dihydrofolate synthase activity
BA6348_19850	COG0525	valine-tRNA ligase activity
BA6348_19885	COG1388	LysM domain
BA6348_19900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BA6348_19915	COG1695	Transcriptional regulator
BA6348_19920	COG0737	Belongs to the 5'-nucleotidase family
BA6348_19925	COG0596	Alpha beta hydrolase
BA6348_19940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BA6348_19945	COG0113	porphobilinogen synthase activity
BA6348_19955	COG0181	hydroxymethylbilane synthase activity
BA6348_19960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA6348_19965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BA6348_19975	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BA6348_19975	COG3291	Pkd domain containing protein
BA6348_19980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BA6348_19990	COG0470	DNA polymerase III
BA6348_19990	COG1067	ATP-dependent peptidase activity
BA6348_19995	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BA6348_20005	COG0544	peptidyl-prolyl cis-trans isomerase activity
BA6348_20010	COG0622	Phosphoesterase
BA6348_20015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BA6348_20020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BA6348_20035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BA6348_20040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA6348_20105	COG2801	Transposase and inactivated derivatives
BA6348_20145	COG3209	COG3209 Rhs family protein
BA6348_20205	COG0583	DNA-binding transcription factor activity
BA6348_20235	COG4608	Belongs to the ABC transporter superfamily
BA6348_20240	COG0444	Belongs to the ABC transporter superfamily
BA6348_20245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_20250	COG0601	transmembrane transport
BA6348_20255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA6348_20260	COG3829	transcription factor binding
BA6348_20260	COG3290	protein histidine kinase activity
BA6348_20265	COG4166	transmembrane transport
BA6348_20280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BA6348_20290	COG5337	Spore coat protein CotH
BA6348_20305	COG1473	amidohydrolase
BA6348_20315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA6348_20335	COG1940	carbohydrate kinase activity
BA6348_20355	COG0673	inositol 2-dehydrogenase activity
BA6348_20360	COG0395	ABC-type sugar transport system, permease component
BA6348_20395	COG2197	response regulator
BA6348_20400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_20425	COG1846	Transcriptional regulator
BA6348_20430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BA6348_20435	COG1053	succinate dehydrogenase
BA6348_20440	COG2009	succinate dehydrogenase
BA6348_20445	COG1719	4-vinyl reductase, 4VR
BA6348_20455	COG0322	excinuclease ABC activity
BA6348_20470	COG0411	ABC transporter
BA6348_20485	COG0683	leucine binding
BA6348_20490	COG3118	belongs to the thioredoxin family
BA6348_20500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BA6348_20505	COG2086	electron transfer activity
BA6348_20510	COG1024	Enoyl-CoA hydratase
BA6348_20515	COG1309	transcriptional regulator
BA6348_20520	COG0318	PFAM AMP-dependent synthetase and ligase
BA6348_20525	COG1316	TRANSCRIPTIONal
BA6348_20530	COG0183	Belongs to the thiolase family
BA6348_20535	COG2264	protein methyltransferase activity
BA6348_20545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA6348_20550	COG2244	polysaccharide biosynthetic process
BA6348_20590	COG0438	transferase activity, transferring glycosyl groups
BA6348_20590	COG0297	glycogen (starch) synthase activity
BA6348_20595	COG2362	D-Aminopeptidase
BA6348_20605	COG1278	Cold shock
BA6348_20610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BA6348_20625	COG3766	membrane
BA6348_20630	COG1193	negative regulation of DNA recombination
BA6348_20640	COG1691	(AIR) carboxylase
BA6348_20645	COG1606	tRNA processing
BA6348_20650	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BA6348_20660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BA6348_20670	COG1063	alcohol dehydrogenase
BA6348_20680	COG0583	DNA-binding transcription factor activity
BA6348_20685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA6348_20690	COG0569	domain protein
BA6348_20700	COG0814	amino acid
BA6348_20710	COG0814	amino acid
BA6348_20715	COG0697	spore germination
BA6348_20765	COG3844	kynureninase activity
BA6348_20770	COG1942	4-Oxalocrotonate Tautomerase
BA6348_20795	COG1414	Transcriptional regulator
BA6348_20800	COG3326	Membrane
BA6348_20805	COG0586	Pfam SNARE associated Golgi protein
BA6348_20825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_20830	COG0473	3-isopropylmalate dehydrogenase activity
BA6348_20835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA6348_20840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BA6348_20845	COG0440	acetolactate synthase activity
BA6348_20850	COG0028	Belongs to the TPP enzyme family
BA6348_20855	COG2046	Belongs to the sulfate adenylyltransferase family
BA6348_20860	COG0175	sulfate reduction
BA6348_20870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BA6348_20875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BA6348_20880	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BA6348_20885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BA6348_20890	COG0840	transmembrane signaling receptor activity
BA6348_20895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BA6348_20905	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BA6348_20920	COG1960	acyl-CoA dehydrogenase activity
BA6348_20925	COG0318	PFAM AMP-dependent synthetase and ligase
BA6348_20935	COG3773	Cell wall hydrolase
BA6348_20975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA6348_20980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA6348_20985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA6348_20990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_21000	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_21035	COG0583	DNA-binding transcription factor activity
BA6348_21040	COG2807	transmembrane transport
BA6348_21045	COG0583	DNA-binding transcription factor activity
BA6348_21050	COG2404	hydrolase activity, acting on ester bonds
BA6348_21055	COG0673	inositol 2-dehydrogenase activity
BA6348_21060	COG3832	glyoxalase III activity
BA6348_21065	COG0640	Transcriptional regulator
BA6348_21070	COG4474	Belongs to the UPF0398 family
BA6348_21075	COG2814	Major facilitator Superfamily
BA6348_21095	COG0456	acetyltransferase
BA6348_21130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BA6348_21135	COG0477	Major facilitator Superfamily
BA6348_21145	COG2204	response regulator
BA6348_21150	COG3852	Histidine kinase
BA6348_21180	COG1609	Transcriptional regulator
BA6348_21190	COG1970	mechanosensitive ion channel activity
BA6348_21215	COG1136	(ABC) transporter
BA6348_21215	COG0577	efflux transmembrane transporter activity
BA6348_21220	COG1136	(ABC) transporter
BA6348_21225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA6348_21230	COG5002	protein histidine kinase activity
BA6348_21235	COG0745	RESPONSE REGULATOR receiver
BA6348_21240	COG0778	Nitroreductase
BA6348_21245	COG1643	Atp-dependent helicase
BA6348_21260	COG0346	lactoylglutathione lyase activity
BA6348_21265	COG0330	HflC and HflK could
BA6348_21285	COG2814	Major facilitator Superfamily
BA6348_21290	COG0583	DNA-binding transcription factor activity
BA6348_21300	COG1132	(ABC) transporter
BA6348_21305	COG1132	(ABC) transporter
BA6348_21315	COG1414	Transcriptional regulator
BA6348_21325	COG0242	peptide deformylase activity
BA6348_21345	COG0788	formyltetrahydrofolate deformylase activity
BA6348_21355	COG0217	transcriptional regulatory protein
BA6348_21370	COG0803	Belongs to the bacterial solute-binding protein 9 family
BA6348_21375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BA6348_21380	COG1121	(ABC) transporter
BA6348_21385	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_21395	COG1454	alcohol dehydrogenase
BA6348_21400	COG1113	amino acid transport
BA6348_21415	COG5002	protein histidine kinase activity
BA6348_21415	COG2205	protein histidine kinase activity
BA6348_21415	COG0784	Response regulator, receiver
BA6348_21420	COG0745	RESPONSE REGULATOR receiver
BA6348_21425	COG3300	MHYT domain
BA6348_21425	COG5001	Diguanylate cyclase
BA6348_21450	COG0326	Molecular chaperone. Has ATPase activity
BA6348_21475	COG1132	(ABC) transporter
BA6348_21485	COG1129	ABC transporter
BA6348_21500	COG2207	Transcriptional regulator
BA6348_21535	COG0583	DNA-binding transcription factor activity
BA6348_21545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_21550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_21555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_21560	COG2814	Major facilitator Superfamily
BA6348_21570	COG2207	Transcriptional regulator
BA6348_21570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_21610	COG4221	oxidoreductase activity
BA6348_21630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_21675	COG2909	trisaccharide binding
BA6348_21690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_21695	COG2169	Transcriptional regulator
BA6348_21700	COG2972	Histidine kinase
BA6348_21700	COG0745	RESPONSE REGULATOR receiver
BA6348_21715	COG1943	Transposase
BA6348_21795	COG2801	Transposase and inactivated derivatives
BA6348_21805	COG1104	cysteine desulfurase activity
BA6348_21865	COG4932	domain protein
BA6348_21865	COG5492	domain, Protein
BA6348_21875	COG1484	DNA-dependent DNA replication
BA6348_21885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BA6348_21895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA6348_21905	COG0237	dephospho-CoA kinase activity
BA6348_21910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BA6348_21915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA6348_21915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA6348_21920	COG2861	carbohydrate metabolic process
BA6348_21925	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA6348_21935	COG2814	Major facilitator Superfamily
BA6348_21940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA6348_21945	COG1566	PFAM secretion protein HlyD family protein
BA6348_21950	COG1846	Transcriptional regulator
BA6348_21955	COG2720	vancomycin resistance protein
BA6348_21965	COG0704	Plays a role in the regulation of phosphate uptake
BA6348_21970	COG5002	protein histidine kinase activity
BA6348_21975	COG0745	RESPONSE REGULATOR receiver
BA6348_21995	COG0039	L-malate dehydrogenase activity
BA6348_22000	COG0538	isocitrate dehydrogenase activity
BA6348_22005	COG0372	Belongs to the citrate synthase family
BA6348_22010	COG0628	permease
BA6348_22015	COG3030	protein affecting phage T7 exclusion by the F plasmid
BA6348_22020	COG0824	Thioesterase
BA6348_22035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA6348_22080	COG0205	6-phosphofructokinase activity
BA6348_22085	COG0825	malonyl-CoA metabolic process
BA6348_22090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BA6348_22100	COG2186	Transcriptional regulator
BA6348_22105	COG0281	malic enzyme
BA6348_22110	COG0587	DNA-directed DNA polymerase activity
BA6348_22125	COG0640	Transcriptional regulator
BA6348_22130	COG4109	DRTGG domain
BA6348_22135	COG4399	Belongs to the UPF0754 family
BA6348_22145	COG0189	ligase activity
BA6348_22150	COG0189	ligase activity
BA6348_22185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BA6348_22195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BA6348_22205	COG0745	RESPONSE REGULATOR receiver
BA6348_22225	COG0450	alkyl hydroperoxide reductase
BA6348_22235	COG0492	ferredoxin-NADP+ reductase activity
BA6348_22245	COG3706	GGDEF domain
BA6348_22255	COG4191	Histidine kinase
BA6348_22260	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BA6348_22265	COG2971	BadF BadG BcrA BcrD
BA6348_22270	COG0395	ABC-type sugar transport system, permease component
BA6348_22275	COG1175	transmembrane transport
BA6348_22285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA6348_22290	COG1737	Transcriptional regulator
BA6348_22295	COG0402	S-adenosylhomocysteine deaminase activity
BA6348_22305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BA6348_22325	COG1404	Belongs to the peptidase S8 family
BA6348_22350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA6348_22355	COG1120	ATPase activity
BA6348_22360	COG0748	coenzyme F420 binding
BA6348_22390	COG1309	transcriptional regulator
BA6348_22395	COG0180	Tryptophanyl-tRNA synthetase
BA6348_22405	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BA6348_22420	COG0410	ABC transporter
BA6348_22435	COG0559	Belongs to the binding-protein-dependent transport system permease family
BA6348_22440	COG1022	Amp-dependent synthetase and ligase
BA6348_22460	COG0583	DNA-binding transcription factor activity
BA6348_22470	COG1683	Conserved Protein
BA6348_22475	COG1072	(Pantothenic acid kinase))
BA6348_22490	COG0783	Belongs to the Dps family
BA6348_22495	COG1473	amidohydrolase
BA6348_22500	COG1619	proteins homologs of microcin C7 resistance protein MccF
BA6348_22510	COG4565	transcriptional regulatory protein
BA6348_22515	COG3290	protein histidine kinase activity
BA6348_22520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BA6348_22525	COG5002	protein histidine kinase activity
BA6348_22530	COG0745	RESPONSE REGULATOR receiver
BA6348_22540	COG1301	dicarboxylic acid transport
BA6348_22550	COG0490	domain, Protein
BA6348_22555	COG0475	glutathione-regulated potassium exporter activity
BA6348_22560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA6348_22580	COG1648	precorrin-2 dehydrogenase activity
BA6348_22580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BA6348_22585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BA6348_22590	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BA6348_22595	COG1492	cobalamin metabolic process
BA6348_22625	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BA6348_22650	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BA6348_22655	COG0406	alpha-ribazole phosphatase activity
BA6348_22660	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BA6348_22670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA6348_22675	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BA6348_22680	COG1846	Transcriptional regulator
BA6348_22715	COG0069	glutamate synthase activity
BA6348_22720	COG0450	alkyl hydroperoxide reductase
BA6348_22760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BA6348_22765	COG0784	Response regulator, receiver
BA6348_22770	COG4191	Histidine kinase
BA6348_22775	COG0765	amino acid transport
BA6348_22780	COG0765	amino acid transport
BA6348_22795	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BA6348_22810	COG2814	Major facilitator Superfamily
BA6348_22820	COG2814	Major facilitator Superfamily
BA6348_22840	COG1845	cytochrome c oxidase, subunit III
BA6348_22845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BA6348_22850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BA6348_22860	COG3180	Ammonia monooxygenase
BA6348_22865	COG0583	DNA-binding transcription factor activity
BA6348_22870	COG0861	Integral membrane protein TerC family
BA6348_22895	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA6348_22900	COG2719	SpoVR family
BA6348_22910	COG2363	Small membrane protein
BA6348_22920	COG3973	AAA domain
BA6348_22945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BA6348_22970	COG1763	Mo-molybdopterin cofactor biosynthetic process
BA6348_22975	COG0303	'Molybdopterin
BA6348_22980	COG3383	formate dehydrogenase (NAD+) activity
BA6348_22995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BA6348_23015	COG0840	transmembrane signaling receptor activity
BA6348_23030	COG1733	regulation of RNA biosynthetic process
BA6348_23085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BA6348_23145	COG0483	inositol monophosphate 1-phosphatase activity
BA6348_23160	COG0833	amino acid
BA6348_23170	COG0583	DNA-binding transcription factor activity
BA6348_23175	COG1380	Effector of murein hydrolase LrgA
BA6348_23180	COG1346	cytolysis
BA6348_23185	COG0730	response to heat
BA6348_23205	COG0436	Aminotransferase
BA6348_23210	COG1522	sequence-specific DNA binding
BA6348_23230	COG1335	isochorismatase
BA6348_23245	COG5001	Diguanylate cyclase
BA6348_23245	COG3300	MHYT domain
BA6348_23300	COG1695	Transcriptional regulator
BA6348_23310	COG1126	abc transporter atp-binding protein
BA6348_23315	COG0765	amino acid transport
BA6348_23325	COG4912	Dna alkylation repair
BA6348_23335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BA6348_23340	COG1378	Sugar-specific transcriptional regulator TrmB
BA6348_23355	COG0840	transmembrane signaling receptor activity
BA6348_23360	COG0745	RESPONSE REGULATOR receiver
BA6348_23360	COG3706	GGDEF domain
BA6348_23385	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BA6348_23390	COG1518	maintenance of DNA repeat elements
BA6348_23390	COG1468	defense response to virus
BA6348_23395	COG0675	Transposase, IS605 OrfB family
BA6348_23405	COG2249	NAD(P)H dehydrogenase (quinone) activity
BA6348_23415	COG2718	Belongs to the UPF0229 family
BA6348_23420	COG2766	serine protein kinase
BA6348_23460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BA6348_23465	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BA6348_23470	COG0328	RNA-DNA hybrid ribonuclease activity
BA6348_23475	COG3382	B3 4 domain protein
BA6348_23480	COG2233	PERMEase
BA6348_23490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_23515	COG1132	(ABC) transporter
BA6348_23520	COG4753	response regulator
BA6348_23520	COG2207	Transcriptional regulator
BA6348_23615	COG3858	chitin binding
BA6348_23620	COG0735	belongs to the Fur family
BA6348_23625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BA6348_23630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA6348_23635	COG2096	Adenosyltransferase
BA6348_23640	COG2226	methyltransferase
BA6348_23645	COG1363	Peptidase, m42
BA6348_23650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BA6348_23660	COG0546	phosphoglycolate phosphatase activity
BA6348_23665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BA6348_23670	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BA6348_23690	COG4555	ABC transporter
BA6348_23700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BA6348_23705	COG2738	Putative neutral zinc metallopeptidase
BA6348_23710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA6348_23730	COG2814	Major facilitator Superfamily
BA6348_23735	COG1132	(ABC) transporter
BA6348_23740	COG3557	Belongs to the UPF0374 family
BA6348_23745	COG0456	acetyltransferase
BA6348_23750	COG1028	Short-chain dehydrogenase reductase Sdr
BA6348_23760	COG0840	transmembrane signaling receptor activity
BA6348_23780	COG1988	membrane-bound metal-dependent
BA6348_23790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BA6348_23800	COG3384	dioxygenase
BA6348_23835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BA6348_23840	COG2197	response regulator
BA6348_23845	COG4585	Histidine kinase
BA6348_23850	COG4758	membrane
BA6348_23855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BA6348_23860	COG1842	Phage shock protein A
BA6348_23875	COG0745	RESPONSE REGULATOR receiver
BA6348_23880	COG5002	protein histidine kinase activity
BA6348_23885	COG2124	cytochrome p450
BA6348_23890	COG1268	BioY protein
BA6348_23910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BA6348_23980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BA6348_23985	COG3842	ATPase activity
BA6348_23995	COG1840	ABC-type Fe3 transport system, periplasmic component
BA6348_24000	COG5002	protein histidine kinase activity
BA6348_24005	COG0745	RESPONSE REGULATOR receiver
BA6348_24010	COG2032	superoxide dismutase activity
BA6348_24015	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BA6348_24020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BA6348_24030	COG1278	Cold shock
BA6348_24035	COG3192	ethanolamine utilization protein
BA6348_24045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA6348_24050	COG2205	protein histidine kinase activity
BA6348_24055	COG0745	RESPONSE REGULATOR receiver
BA6348_24065	COG1131	(ABC) transporter
BA6348_24080	COG0824	Thioesterase
BA6348_24095	COG0697	spore germination
BA6348_24115	COG3850	Histidine kinase
BA6348_24115	COG5002	protein histidine kinase activity
BA6348_24120	COG0745	RESPONSE REGULATOR receiver
BA6348_24125	COG1114	Component of the transport system for branched-chain amino acids
BA6348_24130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BA6348_24140	COG3829	transcription factor binding
BA6348_24140	COG3290	protein histidine kinase activity
BA6348_24145	COG0745	RESPONSE REGULATOR receiver
BA6348_24155	COG2133	pyrroloquinoline quinone binding
BA6348_24170	COG0784	Response regulator, receiver
BA6348_24190	COG2996	Protein conserved in bacteria
BA6348_24215	COG0004	ammonium transporteR
BA6348_24230	COG1247	-acetyltransferase
BA6348_24235	COG0442	prolyl-tRNA aminoacylation
BA6348_24245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BA6348_24275	COG0166	Belongs to the GPI family
BA6348_24280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA6348_24285	COG1136	(ABC) transporter
BA6348_24290	COG0577	efflux transmembrane transporter activity
BA6348_24325	COG1253	flavin adenine dinucleotide binding
BA6348_24335	COG2076	Multidrug Resistance protein
BA6348_24340	COG2076	Multidrug Resistance protein
BA6348_24345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA6348_24365	COG0693	protein deglycase activity
BA6348_24370	COG1733	regulation of RNA biosynthetic process
BA6348_24375	COG1360	Flagellar Motor Protein
BA6348_24380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BA6348_24400	COG0840	transmembrane signaling receptor activity
BA6348_24420	COG0456	acetyltransferase
BA6348_24425	COG1346	cytolysis
BA6348_24435	COG0583	DNA-binding transcription factor activity
BA6348_24450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BA6348_24460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BA6348_24465	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BA6348_24470	COG2258	MOSC domain
BA6348_24475	COG1187	pseudouridine synthase activity
BA6348_24480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_24485	COG0697	spore germination
BA6348_24500	COG1968	undecaprenyl-diphosphatase activity
BA6348_24505	COG1132	(ABC) transporter
BA6348_24510	COG1132	(ABC) transporter
BA6348_24515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA6348_24525	COG4637	Psort location Cytoplasmic, score
BA6348_24535	COG1609	Transcriptional regulator
BA6348_24560	COG1136	(ABC) transporter
BA6348_24570	COG0577	efflux transmembrane transporter activity
BA6348_24580	COG1473	amidohydrolase
BA6348_24590	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BA6348_24605	COG4166	transmembrane transport
BA6348_24640	COG2261	transglycosylase associated protein
BA6348_24645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA6348_24660	COG0666	response to abiotic stimulus
BA6348_24675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_24675	COG2207	Transcriptional regulator
BA6348_24685	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BA6348_24690	COG3152	Membrane
BA6348_24700	COG0673	inositol 2-dehydrogenase activity
BA6348_24710	COG1940	carbohydrate kinase activity
BA6348_24715	COG4608	Belongs to the ABC transporter superfamily
BA6348_24720	COG0444	Belongs to the ABC transporter superfamily
BA6348_24725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_24730	COG0601	transmembrane transport
BA6348_24735	COG0747	negative chemotaxis
BA6348_24740	COG0673	inositol 2-dehydrogenase activity
BA6348_24750	COG2197	response regulator
BA6348_24755	COG4585	Histidine kinase
BA6348_24760	COG3239	Fatty acid desaturase
BA6348_24775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA6348_24780	COG2207	Transcriptional regulator
BA6348_24805	COG1136	(ABC) transporter
BA6348_24815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BA6348_24825	COG0477	Major facilitator Superfamily
BA6348_24870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BA6348_24890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA6348_24930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA6348_24935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA6348_24980	COG3436	PFAM IS66 Orf2 family protein
BA6348_24985	COG4372	Transposase
BA6348_24990	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BA6348_24995	COG1518	maintenance of DNA repeat elements
BA6348_25025	COG0039	L-malate dehydrogenase activity
BA6348_25030	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BA6348_25045	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BA6348_25050	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BA6348_25055	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BA6348_25060	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BA6348_25065	COG1454	alcohol dehydrogenase
BA6348_25065	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_25080	COG0531	amino acid
BA6348_25095	COG1349	DNA-binding transcription factor activity
BA6348_25150	COG4282	regulation of fungal-type cell wall biogenesis
BA6348_25155	COG3328	transposase activity
BA6348_25160	COG2002	toxin-antitoxin pair type II binding
BA6348_25170	COG2203	Gaf domain
BA6348_25170	COG2199	diguanylate cyclase activity
BA6348_25195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BA6348_25210	COG0210	DNA helicase
BA6348_25225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BA6348_25230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BA6348_25270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BA6348_25275	COG1597	lipid kinase activity
BA6348_25280	COG1940	carbohydrate kinase activity
BA6348_25285	COG0697	spore germination
BA6348_25290	COG1668	transmembrane transport
BA6348_25295	COG4555	ABC transporter
BA6348_25315	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BA6348_25320	COG0154	amidase activity
BA6348_25325	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BA6348_25335	COG0688	phosphatidylethanolamine metabolic process
BA6348_25340	COG5001	Diguanylate cyclase
BA6348_25340	COG3300	MHYT domain
BA6348_25345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA6348_25350	COG1012	belongs to the aldehyde dehydrogenase family
BA6348_25365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BA6348_25370	COG0210	DNA helicase
BA6348_25375	COG2720	vancomycin resistance protein
BA6348_25385	COG0531	amino acid
BA6348_25390	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BA6348_25395	COG4496	protein, YerC YecD
BA6348_25400	COG1470	cell adhesion involved in biofilm formation
BA6348_25405	COG0745	RESPONSE REGULATOR receiver
BA6348_25410	COG2205	protein histidine kinase activity
BA6348_25410	COG2770	Histidine kinase
BA6348_25420	COG0517	IMP dehydrogenase activity
BA6348_25420	COG0516	GMP reductase activity
BA6348_25440	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA6348_25445	COG1177	transmembrane transport
BA6348_25450	COG1176	ABC-type spermidine putrescine transport system, permease component I
BA6348_25460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA6348_25525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA6348_25545	COG0559	Belongs to the binding-protein-dependent transport system permease family
BA6348_25555	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BA6348_25565	COG1846	Transcriptional regulator
BA6348_25575	COG0151	Belongs to the GarS family
BA6348_25595	COG3300	MHYT domain
BA6348_25595	COG5001	Diguanylate cyclase
BA6348_25605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BA6348_25610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BA6348_25615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BA6348_25620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BA6348_25625	COG0047	phosphoribosylformylglycinamidine synthase activity
BA6348_25630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BA6348_25635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BA6348_25640	COG1979	alcohol dehydrogenase
BA6348_25645	COG2309	aminopeptidase activity
BA6348_25680	COG2304	oxidoreductase activity
BA6348_25715	COG2304	oxidoreductase activity
BA6348_25730	COG1459	type II secretion system
BA6348_25760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BA6348_25765	COG4372	Transposase
BA6348_25770	COG3436	PFAM IS66 Orf2 family protein
BA6348_25795	COG0405	Gamma-glutamyltransferase
BA6348_25800	COG2059	Chromate
BA6348_25805	COG2059	Chromate
BA6348_25810	COG4608	Belongs to the ABC transporter superfamily
BA6348_25815	COG0444	Belongs to the ABC transporter superfamily
BA6348_25820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA6348_25830	COG0747	negative chemotaxis
BA6348_25840	COG0590	tRNA wobble adenosine to inosine editing
BA6348_25845	COG0577	efflux transmembrane transporter activity
BA6348_25850	COG1136	(ABC) transporter
BA6348_25855	COG2205	protein histidine kinase activity
BA6348_25860	COG0745	RESPONSE REGULATOR receiver
BA6348_25865	COG1595	DNA-templated transcription, initiation
BA6348_25875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BA6348_25880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BA6348_25885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BA6348_25905	COG2252	PERMEase
BA6348_25910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BA6348_25910	COG0519	Catalyzes the synthesis of GMP from XMP
BA6348_25915	COG1305	Transglutaminase-like
BA6348_25925	COG0714	Associated with various cellular activities
BA6348_26065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BA6348_26070	COG2340	Cysteine-rich secretory protein family
BA6348_26080	COG0805	protein transport
BA6348_26085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BA6348_26095	COG0315	cyclic pyranopterin monophosphate synthase activity
BA6348_26095	COG0521	Mo-molybdopterin cofactor biosynthetic process
BA6348_26100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BA6348_26105	COG0488	(ABC) transporter
BA6348_26115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BA6348_26120	COG0456	acetyltransferase
BA6348_26125	COG1214	PFAM Peptidase M22, glycoprotease
BA6348_26130	COG0802	atpase or kinase
BA6348_26135	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BA6348_26140	COG3091	SprT-like family
BA6348_26155	COG2183	response to ionizing radiation
BA6348_26160	COG1191	sigma factor activity
BA6348_26165	COG2172	sigma factor antagonist activity
BA6348_26170	COG1366	Belongs to the anti-sigma-factor antagonist family
BA6348_26175	COG2208	phosphoserine phosphatase activity
BA6348_26180	COG2172	sigma factor antagonist activity
BA6348_26195	COG2337	Toxic component of a toxin-antitoxin (TA) module
BA6348_26200	COG0864	Transcriptional regulator
BA6348_26205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA6348_26225	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BA6348_26230	COG0736	holo-[acyl-carrier-protein] synthase activity
BA6348_26255	COG0640	Transcriptional regulator
BA6348_26275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BA6348_26280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA6348_26290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA6348_26295	COG0581	inorganic phosphate transmembrane transporter activity
BA6348_26300	COG0573	inorganic phosphate transmembrane transporter activity
BA6348_26305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BA6348_26330	COG4166	transmembrane transport
BA6348_26335	COG4166	transmembrane transport
BA6348_26345	COG4166	transmembrane transport
BA6348_26360	COG4166	transmembrane transport
BA6348_26425	COG1999	signal sequence binding