locus-tag	class	description
HZY74_00065	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HZY74_00070	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HZY74_00075	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HZY74_00080	ENOG41084HQ	50S ribosomal protein L30
HZY74_00090	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HZY74_00095	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HZY74_00105	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HZY74_00115	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HZY74_00120	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HZY74_00125	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HZY74_00135	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HZY74_00140	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HZY74_00145	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HZY74_00150	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HZY74_00155	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HZY74_00170	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HZY74_00175	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HZY74_00200	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
HZY74_00220	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HZY74_00225	ENOG4108ZCF	integral membrane protein
HZY74_00230	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HZY74_00240	ENOG4107QI1	Mate efflux family protein
HZY74_00275	ENOG4107QX3	carboxylase
HZY74_00290	ENOG4105C1J	atp-dependent rna helicase
HZY74_00310	ENOG4108Z4V	iron-sulfur cluster assembly
HZY74_00315	ENOG4105VG1	fes assembly suf system protein
HZY74_00320	ENOG4105C9B	Cysteine desulfurase
HZY74_00325	ENOG4105JRK	feS assembly protein SufD
HZY74_00345	ENOG4105DHZ	alpha beta
HZY74_00370	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HZY74_00375	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HZY74_00395	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HZY74_00425	ENOG4105BZU	Histidine kinase
HZY74_00430	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HZY74_00435	ENOG4108UQY	Iron-storage protein
HZY74_00440	ENOG41082BM	Transcriptional regulator, arsr family
HZY74_00455	ENOG4105CD3	dihydroorotase
HZY74_00465	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HZY74_00480	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HZY74_00500	ENOG4105DVP	Adenine-specific
HZY74_00505	ENOG4105CA9	Pyruvate kinase
HZY74_00550	ENOG4105KTQ	flagellar basal-body rod protein
HZY74_00555	ENOG4105CGA	flagellar basal-body rod protein FlgG
HZY74_00565	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HZY74_00590	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HZY74_00600	ENOG410846T	CoA-transferase family III
HZY74_00615	ENOG4108UXN	response regulator
HZY74_00630	ENOG4105D7B	Flagellar biosynthesis protein flha
HZY74_00640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZY74_00645	ENOG4105DD5	Flagellar motor switch protein
HZY74_00655	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HZY74_00660	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HZY74_00665	ENOG4107RDP	Dehydrogenase
HZY74_00675	ENOG4105EWK	phytoene
HZY74_00715	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HZY74_00720	ENOG4105CSH	Transporter
HZY74_00725	ENOG4105E2S	oxidase) subunit II
HZY74_00730	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZY74_00735	ENOG4105CCU	oxidase (Subunit III)
HZY74_00760	ENOG4105CG3	alpha amylase, catalytic region
HZY74_00785	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HZY74_00790	ENOG4105ECY	inositol monophosphatase
HZY74_00800	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZY74_00820	ENOG4105YK5	50S ribosomal protein L36
HZY74_00865	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HZY74_00875	ENOG4108Z4U	Ferredoxin
HZY74_00900	ENOG4105KDC	50s ribosomal protein l28
HZY74_00905	ENOG4105D4A	Cell wall formation (By similarity)
HZY74_00915	ENOG4105DFU	Cell wall formation (By similarity)
HZY74_00950	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HZY74_00985	ENOG4105BZ1	(ABC) transporter
HZY74_01010	ENOG4107XM9	(LipO)protein
HZY74_01040	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HZY74_01060	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HZY74_01080	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HZY74_01095	ENOG4108UUM	single-stranded DNA-binding protein
HZY74_01110	ENOG4108T1X	regulatory protein FlaEY
HZY74_01125	ENOG4107W75	Flagellin
HZY74_01135	ENOG4107W75	Flagellin
HZY74_01175	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HZY74_01230	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZY74_01245	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HZY74_01265	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HZY74_01280	ENOG410846R	homoserine O-acetyltransferase
HZY74_01285	ENOG4105C28	cystathionine
HZY74_01295	ENOG4105C3G	gtp-binding protein
HZY74_01325	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HZY74_01340	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HZY74_01350	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HZY74_01355	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HZY74_01360	ENOG4105BZU	Histidine kinase
HZY74_01365	ENOG4105D6S	protein involved in catabolism of external DNA
HZY74_01370	ENOG4105CPQ	Dehydrogenase
HZY74_01435	ENOG4108N8Y	HfaB protein
HZY74_01445	ENOG4107RAN	Peptidase, M16
HZY74_01465	ENOG4108Z0R	Transferase
HZY74_01470	ENOG4105C9A	Phoh family
HZY74_01475	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HZY74_01480	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HZY74_01510	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HZY74_01515	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HZY74_01520	ENOG4105E4C	Lytic transglycosylase catalytic
HZY74_01585	ENOG4107QPR	SAICAR synthetase
HZY74_01600	ENOG4105E0F	Histidine kinase
HZY74_01665	ENOG4105D48	metallophosphoesterase
HZY74_01680	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HZY74_01695	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HZY74_01705	ENOG4108V1U	phospholipid-binding protein
HZY74_01710	ENOG4105W5Q	DNA repair protein (RadC
HZY74_01720	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HZY74_01725	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HZY74_01730	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HZY74_01760	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HZY74_01765	ENOG4105BZU	Histidine kinase
HZY74_01790	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HZY74_01820	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HZY74_01830	ENOG4108PYU	two-component system response regulator
HZY74_01835	ENOG4108KTQ	Methyltransferase
HZY74_01870	ENOG4105BZU	Histidine kinase
HZY74_01875	ENOG4105CGU	Enoyl-CoA hydratase
HZY74_01880	ENOG4107R1Y	fructose-bisphosphate aldolase
HZY74_01905	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HZY74_01910	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HZY74_01915	ENOG4105DVC	DnaJ domain protein
HZY74_01940	ENOG4108VTS	Membrane
HZY74_01945	ENOG4105KAF	membrAne
HZY74_02015	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZY74_02045	ENOG4105BZU	Histidine kinase
HZY74_02050	ENOG4105F7F	Chaperone
HZY74_02055	ENOG4105QFC	Hsc56 co-chaperone of HscC
HZY74_02075	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HZY74_02080	ENOG4105C8Y	Acetylornithine aminotransferase
HZY74_02090	ENOG4105DBV	ornithine carbamoyltransferase
HZY74_02105	ENOG4108VCT	Sulfite exporter TauE/SafE
HZY74_02115	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HZY74_02140	ENOG4105BZU	Histidine kinase
HZY74_02165	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HZY74_02180	ENOG4105C0H	protease
HZY74_02190	ENOG4105DA4	cytochrome c-type biogenesis protein
HZY74_02195	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HZY74_02210	ENOG4105IFJ	Histidine kinase
HZY74_02215	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HZY74_02230	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HZY74_02245	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZY74_02250	ENOG4105DWF	phosphomethylpyrimidine kinase
HZY74_02270	ENOG4105EEI	dihydropteroate synthase
HZY74_02310	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HZY74_02325	ENOG4105SG9	biopolymer transport protein, ExbD
HZY74_02330	ENOG4105E02	MotA TolQ exbB proton channel
HZY74_02340	ENOG4107YD3	Thioesterase
HZY74_02360	ENOG4105C1G	acyl-Coa dehydrogenase
HZY74_02370	ENOG4105CC9	acyl-Coa dehydrogenase
HZY74_02405	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HZY74_02420	ENOG4105DCM	major facilitator superfamily
HZY74_02425	ENOG4105KT7	mgtC SapB transporter
HZY74_02490	ENOG4108RVA	ribokinase
HZY74_02570	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HZY74_02675	ENOG4108YZN	class I peptide chain release factor
HZY74_02680	ENOG4105C5Q	Transcriptional regulator
HZY74_02685	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HZY74_02710	ENOG4105D0M	Protease HtpX homolog
HZY74_02740	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HZY74_02810	ENOG4107QP8	phosphohexose isomerase
HZY74_02855	ENOG4105CZH	peptidase
HZY74_02860	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HZY74_02865	ENOG4107B2H	carbonic anhydrase
HZY74_02870	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HZY74_02880	ENOG4108T9Y	Inner membrane protein ydcZ
HZY74_02885	ENOG4108KEZ	Dehydrogenase
HZY74_02915	ENOG4105CNG	UPF0061 protein
HZY74_02920	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HZY74_02925	ENOG4107ZSV	Receptor
HZY74_02930	ENOG4105C22	threonyL-tRNA synthetase
HZY74_02935	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HZY74_02950	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HZY74_02965	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HZY74_02995	ENOG4105E39	Enoyl-CoA hydratase
HZY74_03020	ENOG4105HF0	Membrane
HZY74_03030	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HZY74_03035	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HZY74_03045	ENOG4105CP2	von willebrand factor, type a
HZY74_03050	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HZY74_03055	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZY74_03060	ENOG4107QKV	phosphomannomutase
HZY74_03080	ENOG41082BM	Transcriptional regulator, arsr family
HZY74_03095	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HZY74_03100	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HZY74_03105	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HZY74_03125	ENOG4107V6I	Cytosine-specific methyltransferase
HZY74_03150	ENOG4105E4C	Lytic transglycosylase catalytic
HZY74_03160	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HZY74_03175	ENOG4105C7S	Dehydrogenase
HZY74_03190	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HZY74_03205	ENOG4108I5G	Major Facilitator superfamily
HZY74_03215	ENOG4108R86	Transcriptional regulator
HZY74_03240	ENOG4105I8F	Histidine kinase
HZY74_03255	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HZY74_03270	ENOG4107ZYJ	bioY protein
HZY74_03280	ENOG4105CH7	arginosuccinase
HZY74_03285	ENOG4107ZT5	Thiol disulfide interchange protein
HZY74_03320	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HZY74_03340	ENOG4105EB3	Histidine kinase
HZY74_03350	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HZY74_03375	ENOG4105BZU	Histidine kinase
HZY74_03385	ENOG4107QRT	dEAD DEAH box helicase
HZY74_03390	ENOG4105DVT	helicase
HZY74_03395	ENOG4105DIN	metallophosphoesterase
HZY74_03405	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HZY74_03410	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HZY74_03430	ENOG4105CKW	Inner membrane protein yedI
HZY74_03435	ENOG4105EE5	Membrane protein terC
HZY74_03440	ENOG4105C25	Primosomal protein n'
HZY74_03445	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HZY74_03455	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZY74_03460	ENOG4107QN2	dihydrolipoyl dehydrogenase
HZY74_03465	ENOG4105CQZ	Histidine kinase
HZY74_03525	ENOG4105D44	asparaginase
HZY74_03530	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HZY74_03545	ENOG4105FR1	rard protein
HZY74_03550	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HZY74_03555	ENOG4105D6Z	AFG1 family ATPase
HZY74_03570	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HZY74_03610	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HZY74_03630	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HZY74_03660	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HZY74_03665	ENOG4105CT7	inner membrane cred family protein
HZY74_03670	ENOG4105E33	succinate dehydrogenase
HZY74_03675	ENOG4107Z7P	Ferredoxin
HZY74_03700	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HZY74_03745	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HZY74_03755	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZY74_03775	ENOG4105C9K	Endothelin-converting enzyme 1
HZY74_03780	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HZY74_03810	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
HZY74_03815	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HZY74_03855	ENOG4105C0B	DNA polymerase III (alpha subunit)
HZY74_03895	ENOG4105C26	Dehydrogenase
HZY74_03930	ENOG4105D05	Receptor
HZY74_03940	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HZY74_03960	ENOG4105CJR	Integral membrane protein (MviN
HZY74_03965	ENOG4105C31	Tryptophanyl-tRNA synthetase
HZY74_03980	ENOG41060IM	Heme exporter protein
HZY74_04010	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HZY74_04015	ENOG4108JQC	penicillin-binding protein 1A
HZY74_04035	ENOG4105TX3	Histidine kinase
HZY74_04040	ENOG4108UYB	regulatoR
HZY74_04050	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HZY74_04060	ENOG4105HFZ	Membrane
HZY74_04070	ENOG4105C0H	protease
HZY74_04080	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HZY74_04100	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HZY74_04105	ENOG41080PD	NADH ubiquinone oxidoreductase 41 kD complex I subunit
HZY74_04120	ENOG4107835	probably involved in intracellular septation (By similarity)
HZY74_04125	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HZY74_04135	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HZY74_04145	ENOG4107QM5	aconitate hydratase
HZY74_04155	ENOG4105EMU	Dehydrogenase
HZY74_04170	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HZY74_04185	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HZY74_04200	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HZY74_04225	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HZY74_04255	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HZY74_04260	ENOG4107SVH	Potassium channel protein
HZY74_04290	ENOG4105K63	Thioredoxin
HZY74_04310	ENOG4105CNU	cell division protein FtsK
HZY74_04330	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HZY74_04340	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HZY74_04355	ENOG4105CFG	Acts as a chaperone (By similarity)
HZY74_04360	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HZY74_04365	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HZY74_04375	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HZY74_04385	ENOG4108WRK	Transcriptional regulator
HZY74_04390	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HZY74_04400	ENOG4105C9A	Phoh family
HZY74_04405	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HZY74_04410	ENOG41090R7	Ferric uptake
HZY74_04425	ENOG41083MR	nifu domain-containing protein
HZY74_04435	ENOG4105C7I	Dehydrogenase
HZY74_04440	ENOG4105DSF	transport protein
HZY74_04445	ENOG4105D7A	ATP-binding protein
HZY74_04460	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HZY74_04470	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HZY74_04485	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HZY74_04500	ENOG4108YXA	Membrane
HZY74_04505	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HZY74_04560	ENOG4105DFA	alanine racemase domain protein
HZY74_04565	ENOG4105ETX	regulatoR
HZY74_04580	ENOG4105E39	Enoyl-CoA hydratase
HZY74_04590	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HZY74_04595	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HZY74_04630	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HZY74_04635	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HZY74_04655	ENOG4105DCF	alanine dehydrogenase
HZY74_04660	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HZY74_04675	ENOG4105D06	uba thif-type nad fad binding protein
HZY74_04705	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HZY74_04710	ENOG4106178	UPF0339 protein
HZY74_04715	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HZY74_04730	ENOG4105D7N	magnesium and cobalt transport protein CorA
HZY74_04735	ENOG4105DGW	oligopeptidase A
HZY74_04740	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HZY74_04760	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZY74_04775	ENOG4107S1E	Beta-lactamase
HZY74_04795	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZY74_04810	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HZY74_04815	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HZY74_04820	ENOG4105CHU	acetyl-coa acetyltransferase
HZY74_04830	ENOG4105C2X	Arabinose 5-phosphate isomerase
HZY74_04850	ENOG4108WBT	adenosyltransferase
HZY74_04860	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HZY74_04890	ENOG4105DA5	(ABC) transporter
HZY74_04900	ENOG41080Z8	PHOSPHOCARRIER protein
HZY74_04905	ENOG4105DAS	pts system
HZY74_04915	ENOG4105EB3	Histidine kinase
HZY74_04920	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HZY74_04935	ENOG4105CBX	hi0933 family
HZY74_04945	ENOG4105C2M	dna polymerase I
HZY74_04980	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HZY74_04995	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HZY74_05000	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HZY74_05010	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HZY74_05015	ENOG4105K63	Thioredoxin
HZY74_05020	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HZY74_05035	ENOG4105EHM	Aminoglycoside phosphotransferase
HZY74_05040	ENOG4108E87	P-loop hydrolase UPF0079
HZY74_05045	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HZY74_05060	ENOG4105FYV	Amp nucleosidase
HZY74_05080	ENOG4105CRQ	synthase (Component I)
HZY74_05160	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HZY74_05180	ENOG4105MYN	Zinc uptake regulation protein
HZY74_05190	ENOG4105C26	Dehydrogenase
HZY74_05210	ENOG4105DWY	Agmatine deiminase
HZY74_05225	ENOG4105E0R	Deoxyhypusine synthase
HZY74_05245	ENOG4105D5T	phosphonate abc transporter
HZY74_05285	ENOG4105VMP	Transcriptional regulator
HZY74_05295	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HZY74_05305	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HZY74_05315	ENOG4105D7Z	glutathione synthase
HZY74_05325	ENOG4105BZU	Histidine kinase
HZY74_05330	ENOG4105EYM	Major Facilitator superfamily
HZY74_05335	ENOG4105C6K	Malic enzyme
HZY74_05340	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HZY74_05350	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HZY74_05390	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HZY74_05395	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HZY74_05405	ENOG4105CAK	Cell division ATP-binding protein ftsE
HZY74_05420	ENOG4105E9Q	Acyl-transferase
HZY74_05430	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HZY74_05435	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZY74_05460	ENOG4105VTR	Integrase
HZY74_05540	ENOG4105F0N	pyrophosphate phospho-hydrolase
HZY74_05545	ENOG4105CGZ	zinc metallopeptidase
HZY74_05560	ENOG4108UPT	UPF0178 protein
HZY74_05575	ENOG4105C10	Electron transfer flavoprotein
HZY74_05610	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HZY74_05625	ENOG4105CFH	Aspartokinase
HZY74_05655	ENOG4105VW4	glutaredoxin 3
HZY74_05670	ENOG4105M6F	mutator MutT protein
HZY74_05675	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HZY74_05685	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HZY74_05705	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HZY74_05715	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HZY74_05725	ENOG4105CN1	protease
HZY74_05730	ENOG4105C26	Dehydrogenase
HZY74_05755	ENOG41074H6	response regulator
HZY74_05770	ENOG4105DEN	Luciferase family
HZY74_05775	ENOG4105D74	hydrolase
HZY74_05800	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZY74_05805	ENOG4105CHU	acetyl-coa acetyltransferase
HZY74_05815	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HZY74_05835	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HZY74_05845	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HZY74_05855	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HZY74_05875	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HZY74_05880	ENOG4105XA0	heptosyltransferase ii
HZY74_05885	ENOG4105XA0	heptosyltransferase ii
HZY74_05890	ENOG4108YIQ	Alpha beta hydrolase
HZY74_05895	ENOG4105EPD	Oligopeptide transporter, Opt family
HZY74_05900	ENOG4105CI3	gtp-binding protein typa
HZY74_05905	ENOG4105Y3U	Transglycosylase-associated protein
HZY74_05980	ENOG4108ZT0	50S ribosomal protein l17
HZY74_06000	ENOG4105CJ1	ABC, transporter
HZY74_06020	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HZY74_06030	ENOG4105DUX	Transporter
HZY74_06060	ENOG4105BZE	flagellar hook protein, FlgE
HZY74_06065	ENOG4105W00	Flagellar hook capping protein
HZY74_06090	ENOG4105DHJ	ABC, transporter
HZY74_06095	ENOG4108SNX	Mammalian cell entry related domain protein
HZY74_06135	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HZY74_06180	ENOG4105CI2	imidazolone-5-propionate hydrolase
HZY74_06185	ENOG4105CHU	acetyl-coa acetyltransferase
HZY74_06215	ENOG4108R7K	Metal Dependent Phosphohydrolase
HZY74_06230	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HZY74_06235	ENOG4105RQ9	TPR repeat-containing protein
HZY74_06245	ENOG41060XD	Flagellar protein FlaF
HZY74_06250	ENOG4108TPP	exopolysaccharide synthesis
HZY74_06265	ENOG4105C1G	acyl-Coa dehydrogenase
HZY74_06280	ENOG4105CJW	magnesium transporter
HZY74_06310	ENOG4105DQ4	alcohol dehydrogenase
HZY74_06320	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HZY74_06340	ENOG4107QJZ	Glycosyl transferase, family 2
HZY74_06400	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HZY74_06405	ENOG4108Z03	MAF-like protein
HZY74_06415	ENOG4105VYE	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HZY74_06430	ENOG4108ZZF	transport protein (ExbD)
HZY74_06450	ENOG4105DZ1	carboxypeptidase
HZY74_06460	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HZY74_06490	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HZY74_06505	ENOG4105W0E	50S ribosomal protein L33
HZY74_06540	ENOG4105C1G	acyl-Coa dehydrogenase
HZY74_06550	ENOG4105CSU	acyl-Coa dehydrogenase
HZY74_06555	ENOG4108Z6Z	Transcriptional regulator
HZY74_06560	ENOG4105D64	Mechanosensitive ion channel
HZY74_06585	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HZY74_06615	ENOG4105E3B	Multicopper oxidase
HZY74_06660	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HZY74_06720	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HZY74_06725	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HZY74_06740	ENOG4108VZM	50s ribosomal protein L10
HZY74_06745	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HZY74_06750	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HZY74_06765	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HZY74_06770	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HZY74_06775	ENOG4105HHA	aminodeoxychorismate lyase
HZY74_06785	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HZY74_06795	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HZY74_06800	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HZY74_06825	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HZY74_06865	ENOG4105C5H	ABC transporter
HZY74_06890	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HZY74_06895	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HZY74_06910	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HZY74_06925	ENOG4105C9M	aspartyl-trna synthetase
HZY74_06940	ENOG4107RTZ	reductase
HZY74_06955	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HZY74_06965	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HZY74_06970	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HZY74_06975	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HZY74_06980	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HZY74_07000	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HZY74_07030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZY74_07045	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HZY74_07075	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HZY74_07085	ENOG4105MP9	class II Aldolase
HZY74_07100	ENOG4105BZS	acriflavin resistance protein
HZY74_07110	ENOG4105CE1	Ferrous iron transport protein b
HZY74_07135	ENOG4108JJ7	ABC transporter
HZY74_07155	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZY74_07160	ENOG4105D49	3-dehydroquinate synthase
HZY74_07165	ENOG4105D64	Mechanosensitive ion channel
HZY74_07180	ENOG4105C5X	domain protein
HZY74_07205	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HZY74_07235	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HZY74_07245	ENOG4105BZU	Histidine kinase
HZY74_07265	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZY74_07280	ENOG4105GKE	subunit e
HZY74_07300	ENOG4107R0R	NADH dehydrogenase subunit g
HZY74_07305	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HZY74_07310	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZY74_07315	ENOG4105DF2	NADH dehydrogenase subunit j
HZY74_07330	ENOG4105C8S	subunit m
HZY74_07335	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZY74_07340	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HZY74_07345	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HZY74_07360	ENOG4105IIU	Aminopeptidase
HZY74_07370	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HZY74_07375	ENOG4105D60	lipoprotein releasing system transmembrane protein
HZY74_07380	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZY74_07405	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HZY74_07410	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HZY74_07415	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HZY74_07435	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HZY74_07450	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HZY74_07460	ENOG4105GYT	Protein of unknown function (DUF1009)
HZY74_07465	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HZY74_07470	ENOG4105BZN	citrate synthase
HZY74_07475	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HZY74_07485	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HZY74_07490	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HZY74_07495	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HZY74_07510	ENOG4105D8X	mechanosensitive ion channel
HZY74_07525	ENOG4105DXN	mazG family
HZY74_07530	ENOG4105CT4	transporter
HZY74_07545	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HZY74_07550	ENOG4105CEY	Amp-dependent synthetase and ligase
HZY74_07560	ENOG4108Z1B	Cyclase dehydrase
HZY74_07565	ENOG4105DZG	Dehydrogenase
HZY74_07575	ENOG4105D5U	fad dependent oxidoreductase
HZY74_07600	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HZY74_07610	ENOG4108JYK	Dehydrogenase
HZY74_07615	ENOG4105CPP	Dehydrogenase, E1 component
HZY74_07630	ENOG4105C7S	Dehydrogenase
HZY74_07640	ENOG4107QN2	dihydrolipoyl dehydrogenase
HZY74_07655	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
HZY74_07660	ENOG4105F8V	Hydrolase, tatD family
HZY74_07665	ENOG4107QRG	dna polymerase iii
HZY74_07670	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HZY74_07675	ENOG4105K6T	rare lipoprotein A
HZY74_07690	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HZY74_07695	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HZY74_07705	ENOG4105ER2	Ompa motb domain protein
HZY74_07710	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HZY74_07715	ENOG4105D0M	Protease HtpX homolog
HZY74_07720	ENOG4108V0P	LemA family
HZY74_07725	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZY74_07765	ENOG4105C3F	Signal peptidase i
HZY74_07770	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HZY74_07775	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HZY74_07780	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HZY74_07805	ENOG4105E39	Enoyl-CoA hydratase
HZY74_07815	ENOG4105C1G	acyl-Coa dehydrogenase
HZY74_07820	ENOG4105D52	delta-aminolevulinic acid dehydratase
HZY74_07825	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HZY74_07835	ENOG4105CP7	Triose-phosphate isomerase
HZY74_07845	ENOG4105CRQ	synthase (Component I)
HZY74_07855	ENOG4107QYG	anthranilate phosphoribosyltransferase
HZY74_07860	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HZY74_07865	ENOG4105F0I	Aminotransferase
HZY74_07870	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZY74_07875	ENOG4105ES5	Histidine kinase
HZY74_07880	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HZY74_07895	ENOG4105CEV	competence damage-inducible protein
HZY74_07905	ENOG4107U9T	Pfam:Ribonuclease_BN
HZY74_07920	ENOG4105CB5	ATP-dependent DNA helicase recG
HZY74_07930	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HZY74_07935	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HZY74_07945	ENOG4105KHC	sulfurtransferase
HZY74_07950	ENOG4105CK2	sodium dicarboxylate symporter
HZY74_07955	ENOG4107QXX	ABC transporter
HZY74_07995	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HZY74_08005	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HZY74_08020	ENOG4105E0X	reductase
HZY74_08035	ENOG4108UJD	30S ribosomal protein S9
HZY74_08040	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HZY74_08065	ENOG4105WJX	transcriptional regulator MERR family
HZY74_08070	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HZY74_08100	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HZY74_08110	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HZY74_08120	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HZY74_08125	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HZY74_08140	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HZY74_08145	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HZY74_08155	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HZY74_08160	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HZY74_08180	ENOG4105ERG	peptidase m48, ste24p
HZY74_08195	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HZY74_08200	ENOG4105E9H	Lytic Murein transglycosylase
HZY74_08205	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HZY74_08210	ENOG4108IHU	transport system permease protein
HZY74_08230	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HZY74_08245	ENOG4105CUB	amino acid
HZY74_08350	ENOG4107QS4	23S rRNA
HZY74_08365	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HZY74_08415	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HZY74_08435	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HZY74_08445	ENOG41063H4	Flagellar basal-body protein flbY
HZY74_08460	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HZY74_08465	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HZY74_08490	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HZY74_08510	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HZY74_08520	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HZY74_08530	ENOG4105DP0	ferredoxin-NADP reductase
HZY74_08590	ENOG4105DUX	Transporter
HZY74_08615	ENOG4107EFR	Flavocytochrome c
HZY74_08620	ENOG4107ZSV	Receptor
HZY74_08625	ENOG4107SFI	Major Facilitator superfamily
HZY74_08650	ENOG4105CHR	reductase
HZY74_08665	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HZY74_08670	ENOG4105E1F	short-chain dehydrogenase reductase
HZY74_08680	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HZY74_08685	ENOG4105DRR	Transcriptional regulator, GntR family
HZY74_08710	ENOG4105CEY	Amp-dependent synthetase and ligase
HZY74_08725	ENOG4108M9J	MaoC like domain protein
HZY74_08745	ENOG4105C1G	acyl-Coa dehydrogenase
HZY74_08775	ENOG4105FDP	GntR family transcriptional regulator
HZY74_08790	ENOG4105D2B	acyl-CoA dehydrogenase
HZY74_08800	ENOG4105CHU	acetyl-coa acetyltransferase
HZY74_08805	ENOG4108R85	Short chain dehydrogenase
HZY74_08810	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZY74_08815	ENOG4105CHR	reductase
HZY74_08820	ENOG4105E39	Enoyl-CoA hydratase
HZY74_08830	ENOG4105E39	Enoyl-CoA hydratase
HZY74_08850	ENOG4105C1G	acyl-Coa dehydrogenase
HZY74_08855	ENOG4105D5U	fad dependent oxidoreductase
HZY74_08970	ENOG4105CI2	imidazolone-5-propionate hydrolase
HZY74_08985	ENOG4105CGP	Urocanate hydratase
HZY74_08990	ENOG4105C84	Histidine ammonia-lyase
HZY74_09005	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HZY74_09055	ENOG4105M08	Membrane
HZY74_09100	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HZY74_09130	ENOG41063SB	peptidase
HZY74_09135	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HZY74_09150	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HZY74_09160	ENOG4105BZU	Histidine kinase
HZY74_09190	ENOG4105EEQ	Na H antiporter
HZY74_09195	ENOG4105C1G	acyl-Coa dehydrogenase
HZY74_09210	ENOG4105C5F	glutamine synthetase
HZY74_09225	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HZY74_09230	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HZY74_09235	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HZY74_09260	ENOG4107QX8	SPFH domain, Band 7 family protein
HZY74_09295	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HZY74_09305	ENOG4105CSU	acyl-Coa dehydrogenase
HZY74_09340	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HZY74_09345	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HZY74_09365	ENOG41082CH	UPF0145 protein
HZY74_09380	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HZY74_09430	ENOG4105C9Q	fumarate hydratase class II
HZY74_09445	ENOG41087AY	ADP-Ribose pyrophosphatase
HZY74_09510	ENOG4108RZE	Tetr family transcriptional regulator
HZY74_09520	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HZY74_09540	ENOG4105FE9	pseudouridine synthase
HZY74_09545	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HZY74_09565	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HZY74_09575	ENOG4105CXT	aspartate transcarbamylase
HZY74_09580	ENOG4105CD3	dihydroorotase
HZY74_09600	ENOG4105C79	DNA protecting protein DprA
HZY74_09635	ENOG4105EXC	Acyl-transferase
HZY74_09660	ENOG4105D3Q	Sugar transferase
HZY74_09695	ENOG4107V1M	polysaccharide export protein
HZY74_09760	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HZY74_09765	ENOG4105KJF	protein tyrosine phosphatase
HZY74_09770	ENOG4106H78	methyltransferase
HZY74_09805	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HZY74_09815	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZY74_09825	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HZY74_09845	ENOG4105BZU	Histidine kinase
HZY74_09850	ENOG4105D9U	N-acetyltransferase
HZY74_09855	ENOG4105C1V	Peptidase, M16
HZY74_09860	ENOG4108R6F	Surfeit locus 1 family protein
HZY74_09870	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HZY74_09880	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HZY74_09885	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZY74_09945	ENOG4105C4R	Atp-dependent dna helicase
HZY74_09950	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HZY74_09970	ENOG4105FA0	parb-like partition protein
HZY74_10175	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HZY74_10210	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HZY74_10215	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HZY74_10260	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HZY74_10270	ENOG4105CPC	Aldo Keto reductase
HZY74_10275	ENOG4105DC7	peptidase M24
HZY74_10280	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HZY74_10290	ENOG4105D7W	serine acetyltransferase
HZY74_10295	ENOG41069NU	Nitroreductase
HZY74_10315	ENOG41080HT	Transcriptional regulator, arsr family
HZY74_10320	ENOG4108V62	Rhodanese domain protein
HZY74_10335	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HZY74_10355	ENOG4105C28	cystathionine
HZY74_10365	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HZY74_10400	ENOG4105C8N	cysteinyl-tRNA synthetase
HZY74_10405	ENOG4105EUJ	GTP cyclohydrolase i
HZY74_10410	ENOG4108ZZF	transport protein (ExbD)
HZY74_10420	ENOG4105CV8	reductase
HZY74_10425	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HZY74_10480	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HZY74_10485	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HZY74_10505	ENOG4105EGS	Mechanosensitive ion channel
HZY74_10515	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZY74_10525	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HZY74_10550	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HZY74_10555	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HZY74_10560	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HZY74_10570	ENOG4105CDU	Replicative dna helicase
HZY74_10580	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HZY74_10605	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HZY74_10610	ENOG4105UBK	short-chain dehydrogenase reductase
HZY74_10620	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HZY74_10635	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HZY74_10655	ENOG4105KUZ	arsenate reductase
HZY74_10675	ENOG4105VD1	ATP synthase subunit C
HZY74_10680	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HZY74_10695	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HZY74_10715	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HZY74_10740	ENOG4105C75	arginyL-tRNA synthetase
HZY74_10750	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HZY74_10755	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HZY74_10775	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HZY74_10780	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HZY74_10785	ENOG4108ESX	Receptor
HZY74_10800	ENOG4106H3A	restriction
HZY74_10820	ENOG4105EI2	Pseudouridine synthase
HZY74_10845	ENOG4105D3G	Pseudouridine synthase
HZY74_10865	ENOG4105D1H	recombination factor protein RarA
HZY74_10885	ENOG4105CTB	Polyprenyl synthetase
HZY74_10900	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HZY74_10955	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HZY74_10965	ENOG4107SZR	mannose-6-phosphate isomerase
HZY74_11010	ENOG4107E2E	PKHD-type hydroxylase
HZY74_11020	ENOG4105D9N	nucleoside
HZY74_11055	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HZY74_11060	ENOG4105E0F	Histidine kinase
HZY74_11070	ENOG4105II7	pyrroline-5-carboxylate reductase
HZY74_11085	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HZY74_11095	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HZY74_11100	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HZY74_11110	ENOG4105D05	Receptor
HZY74_11115	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HZY74_11125	ENOG4105CPF	Cell wall formation (By similarity)
HZY74_11150	ENOG4105KPV	Transcriptional regulator
HZY74_11155	ENOG4105DSQ	Nitric oxide reductase
HZY74_11170	ENOG4105EN6	Membrane
HZY74_11180	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HZY74_11185	ENOG4105CSR	polyphosphate kinase 2
HZY74_11190	ENOG4107S1E	Beta-lactamase
HZY74_11275	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
HZY74_11290	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZY74_11295	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HZY74_11305	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HZY74_11310	ENOG4105D5Q	Arginine ornithine antiporter
HZY74_11330	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HZY74_11350	ENOG4107R6U	sodium dicarboxylate symporter
HZY74_11360	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HZY74_11375	ENOG4105C3M	thioredoxin reductase
HZY74_11385	ENOG410903D	sensor protein
HZY74_11405	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HZY74_11410	ENOG4108EU5	L-aspartate oxidase
HZY74_11425	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZY74_11440	ENOG4105BZU	Histidine kinase
HZY74_11440	ENOG4105BZU	Histidine kinase
HZY74_11460	ENOG4105CJ1	ABC, transporter
HZY74_11465	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
HZY74_11495	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HZY74_11525	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HZY74_11535	ENOG4105D07	Signal peptide peptidase, SppA
HZY74_11540	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HZY74_11550	ENOG4105MPN	Membrane
HZY74_11560	ENOG4108ZGC	gaf domain protein
HZY74_11590	ENOG4105EAH	synthase
HZY74_11595	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZY74_11600	ENOG4105BZ1	(ABC) transporter
HZY74_11605	ENOG41082FS	50S ribosomal protein L31
HZY74_11645	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HZY74_11660	ENOG4105BZU	Histidine kinase
HZY74_11665	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HZY74_11670	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HZY74_11680	ENOG4105K5G	30S ribosomal protein S21
HZY74_11690	ENOG4108IUX	(ABC) transporter
HZY74_11695	ENOG4105DR5	peptidase
HZY74_11705	ENOG4108JQ1	Dehydrogenase
HZY74_11710	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
HZY74_11725	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZY74_11740	ENOG4105E2Z	phosphate ABC transporter (Permease
HZY74_11745	ENOG4105C8U	phosphate abc transporter
HZY74_11750	ENOG4105BZU	Histidine kinase
HZY74_11795	ENOG4105ERG	peptidase m48, ste24p
HZY74_11810	ENOG4107RDJ	Sulfotransferase
HZY74_11820	ENOG4105C12	Phosphoribosylglycinamide synthetase
HZY74_11835	ENOG4108VYJ	response regulator receiver protein
HZY74_11845	ENOG4105CHR	reductase
HZY74_11850	ENOG4108M8H	domain protein
HZY74_11865	ENOG4105DTN	riboflavin biosynthesis protein ribF
HZY74_11870	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HZY74_11910	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HZY74_11940	ENOG4105C5I	Dehydrogenase
HZY74_11950	ENOG41089UC	methyltransferase, type 11
HZY74_11955	ENOG4105SYT	Methylenetetrahydrofolate reductase
HZY74_11960	ENOG4105C3R	Methionine synthase
HZY74_11975	ENOG4105C3R	Methionine synthase
HZY74_12015	ENOG4105CEY	Amp-dependent synthetase and ligase
HZY74_12030	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HZY74_12040	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HZY74_12045	ENOG4105C2I	pirin domain protein
HZY74_12060	ENOG4107S9D	Alpha beta hydrolase
HZY74_12075	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HZY74_12085	ENOG4105BZU	Histidine kinase
HZY74_12120	ENOG4105DK7	lysyl-tRNA synthetase
HZY74_12145	ENOG4105CFU	surface antigen
HZY74_12165	ENOG4105F4X	arginine
HZY74_12170	ENOG4105C26	Dehydrogenase
HZY74_12175	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HZY74_12180	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HZY74_12185	ENOG4105UVF	flagellar hook-basal body complex protein fliE
HZY74_12190	ENOG4108ZC9	flagellar basal-body rod protein flgc
HZY74_12200	ENOG410680W	Flagellar biosynthesis protein, FliO
HZY74_12205	ENOG4105CN7	Flagellar biosynthetic protein FliP
HZY74_12210	ENOG4105K70	DNA-binding protein
HZY74_12240	ENOG4105DUX	Transporter
HZY74_12245	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HZY74_12255	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HZY74_12295	ENOG4105EY8	ABC transporter
HZY74_12325	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HZY74_12365	ENOG4105CKI	cobalamin synthesis protein
HZY74_12370	ENOG4105PGM	cation diffusion facilitator family transporter
HZY74_12380	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HZY74_12385	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HZY74_12390	ENOG4105K46	50S ribosomal protein l27
HZY74_12405	ENOG4105C7B	Threonine dehydratase
HZY74_12410	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HZY74_12415	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HZY74_12440	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HZY74_12470	ENOG4108IUZ	ABC transporter
HZY74_12475	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZY74_12480	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
HZY74_12485	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HZY74_12495	ENOG4108ZNX	Heat shock protein
HZY74_12510	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HZY74_12550	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HZY74_12570	ENOG4105E3A	(ABC) transporter
HZY74_12575	ENOG4105DA5	(ABC) transporter
HZY74_12595	ENOG4107RD7	Flagellar Motor Protein, MotA
HZY74_12605	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HZY74_12620	ENOG4107TY6	Acylneuraminate cytidylyltransferase
HZY74_12640	ENOG4105BZU	Histidine kinase
HZY74_12650	ENOG4108JJ6	Type I secretion system ATPase
HZY74_12660	ENOG4107QP3	malate synthase g
HZY74_12675	ENOG4105C1J	atp-dependent rna helicase
HZY74_12695	ENOG4108I62	cina-like protein
HZY74_12735	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HZY74_12755	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HZY74_12760	ENOG4105BZU	Histidine kinase
HZY74_12765	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HZY74_12790	ENOG4107QPD	alcohol dehydrogenase
HZY74_12795	ENOG4105EUB	pirin domain protein
HZY74_12800	ENOG4105CBN	LysR family transcriptional regulator
HZY74_12810	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HZY74_12815	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HZY74_12840	ENOG4105EFZ	amidohydrolase
HZY74_12860	ENOG4105VZ8	Transcriptional regulator
HZY74_12870	ENOG4105CGY	Dna recombination protein
HZY74_12875	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HZY74_12880	ENOG4105D9R	oxidoreductase
HZY74_12885	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HZY74_12890	ENOG4107QQG	Dehydrogenase
HZY74_12910	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HZY74_12925	ENOG4105CAQ	asparagine synthetase
HZY74_12935	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HZY74_12940	ENOG4108REZ	Imidazole glycerol phosphate synthase
HZY74_12950	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HZY74_12980	ENOG4105D3Q	Sugar transferase
HZY74_12985	ENOG4107SET	aldo keto reductase
HZY74_13005	ENOG4106BRA	Membrane
HZY74_13040	ENOG4105D44	asparaginase
HZY74_13045	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HZY74_13050	ENOG4108UM1	dedA family
HZY74_13065	ENOG4105T0Z	Conserved Protein
HZY74_13070	ENOG4105E3A	(ABC) transporter
HZY74_13100	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HZY74_13105	ENOG4105E09	nadh pyrophosphatase
HZY74_13140	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HZY74_13145	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HZY74_13165	ENOG4105CYM	Glutathione S-transferase
HZY74_13180	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HZY74_13195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZY74_13220	ENOG4105C9X	ppx gppa phosphatase
HZY74_13230	ENOG4105MIR	Phenylalanine 4-monooxygenase
HZY74_13235	ENOG4105EUJ	GTP cyclohydrolase i
HZY74_13250	ENOG4105D00	flagellar biosynthetic protein flhB
HZY74_13270	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HZY74_13285	ENOG4105VZ8	Transcriptional regulator
HZY74_13310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HZY74_13320	ENOG4105CGZ	zinc metallopeptidase
HZY74_13330	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HZY74_13335	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HZY74_13340	ENOG4105DFU	Cell wall formation (By similarity)
HZY74_13360	ENOG4105CJ2	(LipO)protein
HZY74_13375	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HZY74_13380	ENOG4105C01	Dihydroxy-acid dehydratase
HZY74_13400	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HZY74_13410	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZY74_13485	ENOG4105CW7	secretion protein, HlyD family
HZY74_13505	ENOG4107QN2	dihydrolipoyl dehydrogenase
HZY74_13510	ENOG4107QSN	dihydrolipoamide acetyltransferase
HZY74_13515	ENOG4107QSN	dihydrolipoamide acetyltransferase
HZY74_13520	ENOG4105CPP	Dehydrogenase, E1 component
HZY74_13525	ENOG4107R0V	Pyruvate dehydrogenase
HZY74_13530	ENOG4108XM1	transcriptional regulator AsnC family
HZY74_13535	ENOG4105EUB	pirin domain protein
HZY74_13570	ENOG4108ZNX	Heat shock protein