locus-tag	class	description
D9V69_00005	COG0445	tRNA wobble uridine modification
D9V69_00010	COG0356	it plays a direct role in the translocation of protons across the membrane
D9V69_00020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9V69_00050	COG0187	DNA topoisomerase II activity
D9V69_00055	COG0592	DNA-directed DNA polymerase activity
D9V69_00060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9V69_00070	COG0594	ribonuclease P activity
D9V69_00105	COG1484	DNA-dependent DNA replication
D9V69_00115	COG0742	ribosomal rna small subunit methyltransferase
D9V69_00120	COG0552	protein localization to endoplasmic reticulum
D9V69_00125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9V69_00130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9V69_00140	COG0561	phosphatase activity
D9V69_00145	COG0583	DNA-binding transcription factor activity
D9V69_00150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9V69_00160	COG0776	regulation of translation
D9V69_00165	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9V69_00185	COG0081	regulation of translation
D9V69_00195	COG0250	Participates in transcription elongation, termination and antitermination
D9V69_00200	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9V69_00225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9V69_00230	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9V69_00240	COG0165	Argininosuccinate lyase
D9V69_00245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9V69_00255	COG1045	serine acetyltransferase
D9V69_00260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9V69_00265	COG0358	DNA primase activity
D9V69_00285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D9V69_00300	COG2190	(PTS) system
D9V69_00305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9V69_00310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9V69_00315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9V69_00335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9V69_00345	COG1677	Flagellar hook-basal body complex protein FliE
D9V69_00350	COG1766	The M ring may be actively involved in energy transduction
D9V69_00355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9V69_00360	COG1317	bacterial-type flagellum organization
D9V69_00365	COG1157	protein secretion by the type III secretion system
D9V69_00375	COG3144	bacterial-type flagellum assembly
D9V69_00380	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9V69_00385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9V69_00390	COG1338	Plays a role in the flagellum-specific transport system
D9V69_00390	COG3190	flagellar
D9V69_00395	COG1987	bacterial-type flagellum assembly
D9V69_00400	COG1684	flagellar biosynthetic protein fliR
D9V69_00405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9V69_00415	COG2911	Protein conserved in bacteria
D9V69_00420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D9V69_00425	COG0312	modulator of DNA gyrase
D9V69_00435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9V69_00440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9V69_00450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9V69_00465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9V69_00485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9V69_00500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9V69_00510	COG0107	imidazoleglycerol-phosphate synthase activity
D9V69_00515	COG0140	phosphoribosyl-ATP diphosphatase activity
D9V69_00515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9V69_00520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9V69_00525	COG0717	Belongs to the dCTP deaminase family
D9V69_00535	COG0037	tRNA processing
D9V69_00545	COG0307	riboflavin synthase, alpha
D9V69_00560	COG4656	Part of a membrane complex involved in electron transport
D9V69_00570	COG4659	FMN binding
D9V69_00580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9V69_00595	COG0316	Belongs to the HesB IscA family
D9V69_00600	COG0628	permease
D9V69_00605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D9V69_00625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9V69_00630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9V69_00635	COG0072	phenylalanine-tRNA ligase activity
D9V69_00635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9V69_00640	COG0776	regulation of translation
D9V69_00645	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9V69_00655	COG1862	Preprotein translocase
D9V69_00670	COG0302	gtp cyclohydrolase
D9V69_00685	COG0586	Pfam SNARE associated Golgi protein
D9V69_00690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9V69_00695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9V69_00700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9V69_00705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9V69_00710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9V69_00715	COG0505	Belongs to the CarA family
D9V69_00720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9V69_00735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9V69_00740	COG0196	riboflavin kinase activity
D9V69_00760	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9V69_00770	COG0649	NAD binding
D9V69_00770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9V69_00775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
D9V69_00780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D9V69_00785	COG1034	ATP synthesis coupled electron transport
D9V69_00795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9V69_00800	COG0839	Belongs to the complex I subunit 6 family
D9V69_00810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9V69_00815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9V69_00820	COG1007	ATP synthesis coupled electron transport
D9V69_00825	COG0285	dihydrofolate synthase activity
D9V69_00835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9V69_00840	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9V69_00850	COG2890	protein-(glutamine-N5) methyltransferase activity
D9V69_00855	COG2912	Transglutaminase-like superfamily
D9V69_00865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9V69_00870	COG0857	belongs to the CobB CobQ family
D9V69_00870	COG0280	phosphate acetyltransferase
D9V69_00875	COG0633	Ferredoxin
D9V69_00880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9V69_00885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9V69_00890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9V69_00895	COG3416	Protein conserved in bacteria
D9V69_00900	COG0450	alkyl hydroperoxide reductase
D9V69_00905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9V69_00910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9V69_00920	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9V69_00930	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D9V69_00935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9V69_00940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9V69_00950	COG0012	GTP binding
D9V69_00955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9V69_00960	COG0083	homoserine kinase activity
D9V69_00965	COG0527	aspartate kinase activity
D9V69_00965	COG0460	homoserine dehydrogenase
D9V69_00970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D9V69_00980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9V69_00985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9V69_00995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9V69_01000	COG0653	protein targeting
D9V69_01005	COG0237	dephospho-CoA kinase activity
D9V69_01015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D9V69_01020	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9V69_01025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9V69_01045	COG0316	Belongs to the HesB IscA family
D9V69_01050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9V69_01055	COG0849	cell division
D9V69_01060	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9V69_01070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9V69_01075	COG0772	Belongs to the SEDS family
D9V69_01095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9V69_01100	COG0768	penicillin binding
D9V69_01115	COG0440	acetolactate synthase activity
D9V69_01120	COG0028	Belongs to the TPP enzyme family
D9V69_01130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9V69_01135	COG2171	N-acyltransferase activity
D9V69_01140	COG0024	Methionine aminopeptidase
D9V69_01155	COG0528	UMP kinase activity
D9V69_01165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9V69_01170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9V69_01175	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9V69_01185	COG0587	DNA-directed DNA polymerase activity
D9V69_01195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9V69_01200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9V69_01225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9V69_01230	COG0328	RNA-DNA hybrid ribonuclease activity
D9V69_01235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9V69_01250	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D9V69_01255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9V69_01260	COG2914	Belongs to the UPF0125 (RnfH) family
D9V69_01270	COG0590	tRNA wobble adenosine to inosine editing
D9V69_01290	COG0681	Belongs to the peptidase S26 family
D9V69_01300	COG0482	sulfurtransferase activity
D9V69_01305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9V69_01315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9V69_01325	COG2095	MarC family integral membrane protein
D9V69_01330	COG0321	lipoyl(octanoyl) transferase activity
D9V69_01340	COG0284	orotidine-5'-phosphate decarboxylase activity
D9V69_01345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9V69_01355	COG1607	acyl-coa hydrolase
D9V69_01390	COG0697	spore germination
D9V69_01395	COG1187	pseudouridine synthase activity
D9V69_01400	COG0616	signal peptide processing
D9V69_01405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9V69_01405	COG0551	DNA topoisomerase type I activity
D9V69_01410	COG0483	inositol monophosphate 1-phosphatase activity
D9V69_01415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9V69_01420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9V69_01425	COG0124	histidyl-tRNA synthetase
D9V69_01445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9V69_01450	COG2706	6-phosphogluconolactonase activity
D9V69_01455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9V69_01460	COG4591	ABC-type transport system involved in lipoprotein release permease component
D9V69_01465	COG1136	(ABC) transporter
D9V69_01475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9V69_01480	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9V69_01480	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9V69_01485	COG0716	FMN binding
D9V69_01490	COG0415	Belongs to the DNA photolyase family
D9V69_01495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9V69_01500	COG0567	Dehydrogenase, E1 component
D9V69_01505	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9V69_01515	COG0205	6-phosphofructokinase activity
D9V69_01520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9V69_01525	COG0149	triose-phosphate isomerase activity
D9V69_01535	COG0539	negative regulation of cytoplasmic translation
D9V69_01560	COG0492	ferredoxin-NADP+ reductase activity
D9V69_01565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9V69_01575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9V69_01580	COG1121	(ABC) transporter
D9V69_01585	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D9V69_01590	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D9V69_01595	COG0739	heme binding
D9V69_01600	COG0469	pyruvate kinase activity
D9V69_01605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9V69_01615	COG1253	flavin adenine dinucleotide binding
D9V69_01620	COG1214	PFAM Peptidase M22, glycoprotease
D9V69_01625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D9V69_01630	COG2894	cell division
D9V69_01640	COG2813	Specifically methylates the guanine in position
D9V69_01655	COG2885	chlorophyll binding
D9V69_01655	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D9V69_01660	COG0728	peptidoglycan biosynthetic process
D9V69_01670	COG3418	PFAM FlgN family protein
D9V69_01675	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
D9V69_01680	COG1815	bacterial-type flagellum-dependent cell motility
D9V69_01685	COG1558	bacterial-type flagellum-dependent cell motility
D9V69_01690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9V69_01695	COG1749	Flagellar hook protein flgE
D9V69_01700	COG4787	bacterial-type flagellum-dependent cell motility
D9V69_01705	COG4786	Flagellar basal body rod
D9V69_01715	COG1706	bacterial-type flagellum-dependent cell motility
D9V69_01720	COG3951	Flagellar rod assembly protein muramidase FlgJ
D9V69_01725	COG1256	bacterial-type flagellum assembly
D9V69_01730	COG1530	ribonuclease E activity
D9V69_01735	COG0564	pseudouridine synthase activity
D9V69_01735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9V69_01755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9V69_01760	COG0470	DNA polymerase III
D9V69_01765	COG0084	hydrolase, TatD family'
D9V69_01770	COG1263	PTS System
D9V69_01770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9V69_01775	COG0537	adenosine 5'-monophosphoramidase activity
D9V69_01785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D9V69_01790	COG0017	Asparaginyl-tRNA synthetase
D9V69_01805	COG0116	Belongs to the methyltransferase superfamily
D9V69_01805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9V69_01810	COG0488	(ABC) transporter
D9V69_01820	COG0525	valine-tRNA ligase activity
D9V69_01825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9V69_01830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9V69_01835	COG0540	Belongs to the ATCase OTCase family
D9V69_01845	COG0251	oxidation-reduction process
D9V69_01850	COG0513	Belongs to the DEAD box helicase family
D9V69_01855	COG1185	polyribonucleotide nucleotidyltransferase activity
D9V69_01865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9V69_01880	COG0195	Participates in both transcription termination and antitermination
D9V69_01890	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9V69_01900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9V69_01905	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
D9V69_01910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9V69_01915	COG5007	Belongs to the BolA IbaG family
D9V69_01945	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9V69_01950	COG0077	Prephenate dehydratase
D9V69_01950	COG1605	Chorismate mutase
D9V69_01955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9V69_01965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9V69_01970	COG0336	Belongs to the RNA methyltransferase TrmD family
D9V69_01980	COG0312	modulator of DNA gyrase
D9V69_01995	COG0564	pseudouridine synthase activity
D9V69_02000	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9V69_02005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9V69_02010	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9V69_02030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9V69_02035	COG2356	endonuclease I
D9V69_02040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9V69_02045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9V69_02070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9V69_02080	COG0148	phosphopyruvate hydratase activity
D9V69_02085	COG0602	queuosine metabolic process
D9V69_02090	COG0720	synthase
D9V69_02095	COG0739	heme binding
D9V69_02095	COG1388	LysM domain
D9V69_02105	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9V69_02110	COG0529	Catalyzes the synthesis of activated sulfate
D9V69_02125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9V69_02125	COG1648	precorrin-2 dehydrogenase activity
D9V69_02140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9V69_02150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9V69_02165	COG0194	GDP metabolic process
D9V69_02170	COG0354	folic acid binding
D9V69_02175	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D9V69_02180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9V69_02185	COG0019	diaminopimelate decarboxylase activity
D9V69_02195	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9V69_02200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9V69_02205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9V69_02210	COG4535	Mg2 and Co2 transporter CorC
D9V69_02215	COG0495	leucyl-tRNA aminoacylation
D9V69_02220	COG1466	dna polymerase III delta subunit
D9V69_02225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9V69_02235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9V69_02240	COG2095	MarC family integral membrane protein
D9V69_02250	COG0191	fructose-bisphosphate aldolase activity
D9V69_02255	COG0668	transmembrane transport
D9V69_02260	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D9V69_02265	COG1074	ATP-dependent DNA helicase activity
D9V69_02270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9V69_02280	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D9V69_02290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9V69_02295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9V69_02300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9V69_02315	COG0142	geranyltranstransferase activity
D9V69_02325	COG2920	part of a sulfur-relay system
D9V69_02335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9V69_02340	COG1845	cytochrome c oxidase, subunit III
D9V69_02345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9V69_02350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9V69_02355	COG0271	Belongs to the BolA IbaG family
D9V69_02365	COG0740	serine-type endopeptidase activity
D9V69_02375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9V69_02380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9V69_02385	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9V69_02390	COG1132	(ABC) transporter
D9V69_02395	COG1132	(ABC) transporter
D9V69_02405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9V69_02410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9V69_02415	COG0326	Molecular chaperone. Has ATPase activity
D9V69_02430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9V69_02445	COG1278	Cold shock
D9V69_02470	COG0009	L-threonylcarbamoyladenylate synthase
D9V69_02495	COG0202	RNA polymerase activity
D9V69_02505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9V69_02515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9V69_02520	COG0201	protein transport
D9V69_02535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9V69_02545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9V69_02550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9V69_02555	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9V69_02560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9V69_02565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D9V69_02580	COG0255	Belongs to the universal ribosomal protein uL29 family
D9V69_02590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9V69_02605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9V69_02655	COG2923	Belongs to the DsrF TusC family
D9V69_02665	COG0545	Peptidyl-prolyl cis-trans isomerase
D9V69_02675	COG0180	Tryptophanyl-tRNA synthetase
D9V69_02680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9V69_02685	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9V69_02690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9V69_02715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9V69_02715	COG0316	Belongs to the HesB IscA family
D9V69_02720	COG2267	carboxylic ester hydrolase activity
D9V69_02725	COG0629	single-stranded DNA binding
D9V69_02730	COG0305	Participates in initiation and elongation during chromosome replication
D9V69_02735	COG0189	ligase activity
D9V69_02745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9V69_02750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9V69_02760	COG1194	a g-specific adenine glycosylase
D9V69_02765	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
D9V69_02775	COG2925	Exonuclease
D9V69_02805	COG1218	3'(2'),5'-bisphosphate nucleotidase
D9V69_02810	COG0359	binds to the 23S rRNA
D9V69_02820	COG0360	Binds together with S18 to 16S ribosomal RNA
D9V69_02825	COG0557	exoribonuclease II activity
D9V69_02835	COG0330	HflC and HflK could
D9V69_02840	COG0330	HflC and HflK could
D9V69_02845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9V69_02855	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9V69_02855	COG2213	PTS system mannitol-specific
D9V69_02860	COG0166	Belongs to the GPI family
D9V69_02865	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D9V69_02875	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9V69_02885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9V69_02890	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9V69_02895	COG0071	Belongs to the small heat shock protein (HSP20) family
D9V69_02900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9V69_02905	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D9V69_02930	COG0306	phosphate transporter
D9V69_02935	COG2814	Major facilitator Superfamily
D9V69_02945	COG1965	Belongs to the frataxin family
D9V69_02975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9V69_02980	COG3118	belongs to the thioredoxin family
D9V69_02985	COG0210	DNA helicase
D9V69_03010	COG0822	iron-sulfur transferase activity
D9V69_03015	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D9V69_03025	COG0633	Ferredoxin
D9V69_03035	COG2976	Protein conserved in bacteria
D9V69_03080	COG0512	Glutamine amidotransferase of anthranilate synthase