locus-tag class description BOC52_00005 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BOC52_00030 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BOC52_00035 ENOG4108MGH Enoyl-CoA hydratase BOC52_00040 ENOG4108KQ6 Enoyl-CoA hydratase BOC52_00045 ENOG41062T2 Acyl carrier protein BOC52_00050 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase BOC52_00085 ENOG4105CH6 catalase BOC52_00090 ENOG4108VAC response regulator BOC52_00095 ENOG4108HRK Histidine kinase BOC52_00145 ENOG4108JEH abc transporter atp-binding protein BOC52_00150 ENOG4106YG3 ABC transporter BOC52_00155 ENOG4105DSP amino acid AbC transporter BOC52_00170 ENOG4108Z9W Outer membrane porin BOC52_00175 ENOG4108SB3 DoxX Family BOC52_00215 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BOC52_00220 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BOC52_00235 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BOC52_00240 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit BOC52_00245 ENOG4105FFC UPF0187 protein BOC52_00250 ENOG4108Z12 YiaAB two helix domain-containing protein BOC52_00260 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BOC52_00265 ENOG4105F0F Oxalate decarboxylase BOC52_00310 ENOG4105CNA YD repeat protein BOC52_00320 ENOG4105CS6 Rhs element vgr protein BOC52_00345 ENOG4108UQS dipeptidase BOC52_00355 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BOC52_00360 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BOC52_00380 ENOG4105ETT transcriptional Regulator, LysR family BOC52_00395 ENOG4108K5P (LipO)protein BOC52_00410 ENOG4108Z9W Outer membrane porin BOC52_00430 ENOG4107UWA esterase BOC52_00460 ENOG4107SVH Potassium channel protein BOC52_00480 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_00505 ENOG4105GVF (ABC) transporter BOC52_00515 ENOG4107RN6 Monooxygenase BOC52_00530 ENOG4105EBM Alpha Beta Hydrolase Fold protein BOC52_00540 ENOG4105CSH Transporter BOC52_00550 ENOG4105EMY transcriptional regulator BOC52_00560 ENOG4105C3M thioredoxin reductase BOC52_00610 ENOG4105F7P transcriptional regulator AsnC family BOC52_00620 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BOC52_00640 ENOG4105UYK outer membrane protein a BOC52_00645 ENOG4105EUR Domain-Containing protein BOC52_00655 ENOG4105C54 Major Facilitator superfamily BOC52_00670 ENOG4105C26 Dehydrogenase BOC52_00680 ENOG4105C7K acetolactate synthase BOC52_00685 ENOG4105CHR reductase BOC52_00690 ENOG4107HP6 Transcriptional regulator BOC52_00730 ENOG4108Z9W Outer membrane porin BOC52_00735 ENOG4107HP6 Transcriptional regulator BOC52_00750 ENOG4107RN3 metallophosphoesterase BOC52_00765 ENOG4105VJY transcriptional regulator BOC52_00780 ENOG4105NNS Autoinducer synthesis protein BOC52_00790 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BOC52_00795 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BOC52_00810 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BOC52_00820 ENOG4108Z9W Outer membrane porin BOC52_00845 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BOC52_00850 ENOG4105XYF acetyltransferase BOC52_00865 ENOG4108Z9W Outer membrane porin BOC52_00880 ENOG4105CUB amino acid BOC52_00890 ENOG4105C26 Dehydrogenase BOC52_00895 ENOG4108UAJ Transcriptional regulator BOC52_00925 ENOG4105EJC lysr family transcriptional regulator BOC52_00935 ENOG4105EJC lysr family transcriptional regulator BOC52_00945 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BOC52_00965 ENOG4105F2V VRR-NUC domain-containing protein BOC52_00980 ENOG4108RVA ribokinase BOC52_00985 ENOG4105DU0 nucleoside hydrolase BOC52_01035 ENOG4107M1U Histone family protein nucleoid-structuring protein H-NS BOC52_01050 ENOG4105C85 amino acid BOC52_01070 ENOG4105EMU Dehydrogenase BOC52_01130 ENOG4105WH1 Two component transcriptional regulator luxr family BOC52_01170 ENOG4107SCK Monooxygenase BOC52_01185 ENOG4107MM9 BNR Asp-box repeat-containing protein BOC52_01205 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BOC52_01210 ENOG4105E2B Taurine dioxygenase BOC52_01230 ENOG4105C8T Leucyl-tRNA synthetase BOC52_01265 ENOG4105DN3 alpha-2-macroglobulin domain protein BOC52_01270 ENOG4105BZ4 penicillin-binding protein BOC52_01280 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BOC52_01285 ENOG4105BZU Histidine kinase BOC52_01335 ENOG4105CGF Aromatic amino acid aminotransferase BOC52_01340 ENOG4105C85 amino acid BOC52_01345 ENOG4108YXU transcriptional regulator AsnC family BOC52_01355 ENOG4105BZU Histidine kinase BOC52_01370 ENOG4108UT2 hemolysin iii BOC52_01415 ENOG4107M1U Histone family protein nucleoid-structuring protein H-NS BOC52_01450 ENOG4105CHR reductase BOC52_01460 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BOC52_01475 ENOG4105CTX dehydratase BOC52_01485 ENOG4105CNN ABC, transporter BOC52_01490 ENOG4105C2J ABC transporter BOC52_01510 ENOG4108Z9W Outer membrane porin BOC52_01520 ENOG4108SC4 )-transporter BOC52_01525 ENOG4105E4E Thioester reductase domain-containing protein BOC52_01535 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase BOC52_01600 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BOC52_01630 ENOG4105WH1 Two component transcriptional regulator luxr family BOC52_01655 ENOG4105CA0 peroxidase BOC52_01680 ENOG4105CHR reductase BOC52_01700 ENOG4105DZC cytosine deaminase BOC52_01705 ENOG4107YHD transcriptional regulator BOC52_01710 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin BOC52_01725 ENOG4108Z9W Outer membrane porin BOC52_01750 ENOG4105CR8 Transcriptional regulator BOC52_01795 ENOG4108Z9W Outer membrane porin BOC52_01830 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BOC52_01845 ENOG4105CTX dehydratase BOC52_01885 ENOG41069M3 Transcriptional regulator BOC52_01890 ENOG4108I5G Major Facilitator superfamily BOC52_01905 ENOG4107YNJ LysR family Transcriptional regulator BOC52_01910 ENOG4105CSH Transporter BOC52_01930 ENOG4105DND Transcriptional regulator BOC52_01960 ENOG4105CHR reductase BOC52_01965 ENOG4105CIH Imidazole acetol-phosphate transaminase BOC52_01975 ENOG4105CP9 extracellular ligand-binding receptor BOC52_02010 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BOC52_02015 ENOG4105DZS Phenylacetate-CoA ligase BOC52_02020 ENOG4105CHU acetyl-coa acetyltransferase BOC52_02045 ENOG4108Z9W Outer membrane porin BOC52_02065 ENOG4108K8U Glycerol operon regulatory protein BOC52_02090 ENOG4105C26 Dehydrogenase BOC52_02100 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BOC52_02105 ENOG4105EVZ LysR family transcriptional regulator BOC52_02175 ENOG4107QZ7 Cellulose synthase catalytic subunit BOC52_02180 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BOC52_02185 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_02200 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_02205 ENOG4107RYR Transcriptional regulator, Crp Fnr family BOC52_02240 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BOC52_02255 ENOG4105F4G Membrane BOC52_02265 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BOC52_02290 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BOC52_02310 ENOG4108WUH Transcriptional regulator, TetR family BOC52_02350 ENOG41067HS methyltransferase BOC52_02395 ENOG4108Z9W Outer membrane porin BOC52_02410 ENOG4105QVC MOSC domain-containing protein BOC52_02415 ENOG4105DHQ Histidine kinase BOC52_02460 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BOC52_02465 ENOG4108Z9W Outer membrane porin BOC52_02475 ENOG4105R1U AraC Family Transcriptional Regulator BOC52_02495 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BOC52_02500 ENOG4105C26 Dehydrogenase BOC52_02515 ENOG4108V8F Transcriptional regulator, MarR family BOC52_02530 ENOG4107EXC regulatoR BOC52_02535 ENOG4105JJR Histidine kinase BOC52_02545 ENOG4107T8P acyl-Coa dehydrogenase BOC52_02550 ENOG4107T8P acyl-Coa dehydrogenase BOC52_02585 ENOG4105CF7 AraC family transcriptional regulator BOC52_02645 ENOG4105CCU oxidase (Subunit III) BOC52_02670 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_02680 ENOG4105T0Z Conserved Protein BOC52_02695 ENOG4107MM9 BNR Asp-box repeat-containing protein BOC52_02795 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BOC52_02850 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BOC52_02875 ENOG4105XJC Two component transcriptional regulator (Winged helix family BOC52_02940 ENOG4106RE7 Cytochrome BOC52_02960 ENOG4105JJR Histidine kinase BOC52_02965 ENOG4107EXC regulatoR BOC52_02975 ENOG4105CSV Glutaminase BOC52_02995 ENOG4105FBW Monooxygenase BOC52_03005 ENOG4105DJY efflux transporter, rnd family, mfp subunit BOC52_03015 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BOC52_03025 ENOG4105E39 Enoyl-CoA hydratase BOC52_03030 ENOG4105E39 Enoyl-CoA hydratase BOC52_03035 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BOC52_03040 ENOG4105C26 Dehydrogenase BOC52_03045 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BOC52_03050 ENOG4105C1G acyl-Coa dehydrogenase BOC52_03055 ENOG4108ZX5 transcriptional regulator BOC52_03100 ENOG4105DTI Phosphonopyruvate decarboxylase BOC52_03155 ENOG4105C7N Xanthine uracil vitamin C permease BOC52_03190 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BOC52_03215 ENOG4108VN5 Inherit from COG: PepSY-associated TM helix BOC52_03225 ENOG4105CNM Receptor BOC52_03245 ENOG4105C0W non-ribosomal peptide synthetase BOC52_03250 ENOG4105C0W non-ribosomal peptide synthetase BOC52_03255 ENOG4105WPR Transcriptional regulator, ARAC family BOC52_03260 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BOC52_03270 ENOG4105VIA Chorismate mutase BOC52_03275 ENOG4105E4F Isochorismate synthase BOC52_03295 ENOG4108IV0 ABC, transporter BOC52_03300 ENOG4105C0Z ABC transporter BOC52_03305 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BOC52_03310 ENOG4105C32 Amino acid ABC transporter (Permease) BOC52_03315 ENOG4105CP9 extracellular ligand-binding receptor BOC52_03365 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme BOC52_03375 ENOG4105ECQ AraC Family Transcriptional Regulator BOC52_03400 ENOG4105CBG Sulfatase BOC52_03430 ENOG4105DVW rieske (2Fe-2S) BOC52_03440 ENOG4105C10 Electron transfer flavoprotein BOC52_03445 ENOG4105DF6 Fe-S oxidoreductase BOC52_03460 ENOG4108IGT Dipeptidase BOC52_03475 ENOG4105ECQ AraC Family Transcriptional Regulator BOC52_03480 ENOG4105E2A Dehydrogenase BOC52_03490 ENOG4105EDQ levansucrase EC 2.4.1.10 BOC52_03495 ENOG4108HKT sucrose-6-phosphate hydrolase BOC52_03505 ENOG4105CW7 secretion protein, HlyD family BOC52_03520 ENOG4105H63 Glycosyl transferase, family 2 BOC52_03525 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_03600 ENOG4105CS6 Rhs element vgr protein BOC52_03605 ENOG4105CS6 Rhs element vgr protein BOC52_03610 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_03685 ENOG4105DTI Phosphonopyruvate decarboxylase BOC52_03720 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BOC52_03765 ENOG41069NU Nitroreductase BOC52_03785 ENOG4105D3R alkyl hydroperoxide reductase BOC52_03790 ENOG4108JU3 Alkyl hydroperoxide reductase BOC52_03830 ENOG4107RCI amp-dependent synthetase and ligase BOC52_03840 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BOC52_03845 ENOG4108MJ1 3-oxoacyl-(ACP) synthase BOC52_03850 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BOC52_03885 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BOC52_03895 ENOG4105CYW agmatinase BOC52_03900 ENOG4105C26 Dehydrogenase BOC52_03905 ENOG4107VRI Transcriptional regulator BOC52_03920 ENOG4108Z86 Glutamine amidotransferase BOC52_03925 ENOG4105CFQ glutamine synthetase BOC52_03930 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BOC52_03945 ENOG4105F38 ABC transporter, permease BOC52_03950 ENOG4105D38 putrescine abc transporter BOC52_03960 ENOG4105CJP fad dependent oxidoreductase BOC52_03965 ENOG4105CJP fad dependent oxidoreductase BOC52_03970 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_04010 ENOG4105DCG PHP domain protein BOC52_04030 ENOG41061WM D-Alanyl-D-Alanine BOC52_04045 ENOG4107SQD Transcriptional regulator, GntR family BOC52_04055 ENOG4108MEJ flavin reductase domain protein BOC52_04070 ENOG4105CR8 Transcriptional regulator BOC52_04100 ENOG4105EFZ amidohydrolase BOC52_04110 ENOG4105CHJ isochorismatase hydrolase BOC52_04115 ENOG4105HEI LysR family (Transcriptional regulator BOC52_04125 ENOG4105EQ0 Major Facilitator superfamily BOC52_04170 ENOG4105CC0 LysR family Transcriptional regulator BOC52_04225 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BOC52_04230 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BOC52_04235 ENOG4105FAW cDP-glucose 4,6-dehydratase BOC52_04240 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BOC52_04250 ENOG4107V1M polysaccharide export protein BOC52_04280 ENOG4105E3R (LipO)protein BOC52_04335 ENOG4105CA0 peroxidase BOC52_04360 ENOG4105DFP Integrase BOC52_04370 ENOG4108YXQ IS66 Orf2 family protein BOC52_04375 ENOG4105E5H Transposase BOC52_04380 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein BOC52_04425 ENOG4107QN1 sodium solute BOC52_04445 ENOG4108TEB UPF0114 protein BOC52_04455 ENOG4108UQY Iron-storage protein BOC52_04460 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BOC52_04490 ENOG4105JQN Transcriptional regulator BOC52_04495 ENOG4105EUB pirin domain protein BOC52_04505 ENOG4107F3C Hemin uptake protein BOC52_04510 ENOG4108ZJF Glcg protein BOC52_04515 ENOG4105HEE Binding Domain protein BOC52_04525 ENOG4105WP5 BOC52_04535 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BOC52_04540 ENOG4105CGF Aromatic amino acid aminotransferase BOC52_04555 ENOG4105CPC Aldo Keto reductase BOC52_04560 ENOG4105D6S protein involved in catabolism of external DNA BOC52_04635 ENOG4105D81 ABC transporter, permease BOC52_04655 ENOG4105DJB Major Facilitator Superfamily BOC52_04660 ENOG4107S9B Shikimate dehydrogenase BOC52_04665 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BOC52_04705 ENOG41080HI glycine oxidase BOC52_04720 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BOC52_04730 ENOG4107QTZ amino acid BOC52_04740 ENOG4105DG4 malate L-lactate dehydrogenase BOC52_04765 ENOG4108SB3 DoxX Family BOC52_04775 ENOG4105DAA L-lactate BOC52_04780 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BOC52_04785 ENOG4107QR9 Iron-sulfur cluster binding protein BOC52_04790 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BOC52_04795 ENOG41073TP transcriptional regulator BOC52_04810 ENOG4107T8P acyl-Coa dehydrogenase BOC52_04820 ENOG4108UMI ABC transporter, permease BOC52_04825 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BOC52_04835 ENOG4105D01 (LipO)protein BOC52_04895 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BOC52_04905 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BOC52_04910 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_04920 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BOC52_04970 ENOG4105C1P efflux transporter, rnd family, mfp subunit BOC52_04980 ENOG4105CBN LysR family transcriptional regulator BOC52_05015 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) BOC52_05050 ENOG4108K8U Glycerol operon regulatory protein BOC52_05065 ENOG4108JPW Aminotransferase BOC52_05070 ENOG4105C26 Dehydrogenase BOC52_05100 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BOC52_05115 ENOG4105CHU acetyl-coa acetyltransferase BOC52_05125 ENOG4107HP6 Transcriptional regulator BOC52_05130 ENOG4108R86 Transcriptional regulator BOC52_05150 ENOG4105CH2 amidohydrolase BOC52_05155 ENOG410811B TRANSCRIPTIONal BOC52_05160 ENOG4105E89 ABC transporter BOC52_05185 ENOG4105D01 (LipO)protein BOC52_05190 ENOG4108Z9W Outer membrane porin BOC52_05220 ENOG4105CMT Dihydroxyacetone kinase BOC52_05225 ENOG4105CPQ Dehydrogenase BOC52_05230 ENOG4105CHR reductase BOC52_05235 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BOC52_05240 ENOG4105CNN ABC, transporter BOC52_05245 ENOG4105C2J ABC transporter BOC52_05250 ENOG4108YZG isomerase BOC52_05260 ENOG4108Z9W Outer membrane porin BOC52_05275 ENOG4107QKW extracellular solute-binding protein family 1 BOC52_05280 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BOC52_05290 ENOG4105ETT transcriptional Regulator, LysR family BOC52_05305 ENOG4106QJH hemin transport protein BOC52_05310 ENOG4107R4I Periplasmic binding protein BOC52_05320 ENOG4105EHG Permease protein BOC52_05335 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BOC52_05340 ENOG4105EN6 Membrane BOC52_05350 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) BOC52_05355 ENOG4105C5W Aldolase BOC52_05365 ENOG4105C4M (Ubiquinol oxidase) subunit I BOC52_05370 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BOC52_05385 ENOG4105HEI LysR family (Transcriptional regulator BOC52_05390 ENOG4105FE1 phytoene synthase BOC52_05400 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BOC52_05485 ENOG4105KT7 mgtC SapB transporter BOC52_05510 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_05515 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E BOC52_05550 ENOG4105C7F AcnD-accessory protein PrpF BOC52_05555 ENOG4108I0Z Aconitate hydratase BOC52_05560 ENOG4105BZN citrate synthase BOC52_05565 ENOG4105CR4 methylisocitrate lyase BOC52_05570 ENOG4108JU7 Transcriptional regulator BOC52_05580 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_05640 ENOG4105E7W lamb ycsf family protein BOC52_05645 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BOC52_05650 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BOC52_05705 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF BOC52_05750 ENOG4105CS6 Rhs element vgr protein BOC52_05790 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_05820 ENOG4108ZG0 Ompa motb domain protein BOC52_05840 ENOG4105JQN Transcriptional regulator BOC52_05850 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BOC52_05855 ENOG4105CAQ asparagine synthetase BOC52_05860 ENOG4105EFA 4-hydroxyphenylacetate BOC52_05880 ENOG4105CWX Alpha-1,2-mannosidase BOC52_05900 ENOG410904N short-chain dehydrogenase reductase BOC52_05915 ENOG4105MWK D-amino acid dehydrogenase, small subunit BOC52_05920 ENOG4107RP9 extracellular solute-binding protein, family 3 BOC52_05945 ENOG4106KR7 LysR family Transcriptional regulator BOC52_05955 ENOG4105CH2 amidohydrolase BOC52_05960 ENOG4105CSH Transporter BOC52_05970 ENOG4105C1J atp-dependent rna helicase BOC52_06005 ENOG4105CNN ABC, transporter BOC52_06010 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BOC52_06065 ENOG4105ETT transcriptional Regulator, LysR family BOC52_06090 ENOG4105C0W non-ribosomal peptide synthetase BOC52_06100 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR BOC52_06105 ENOG4105CA9 Pyruvate kinase BOC52_06110 ENOG4105BZW Glycerate kinase BOC52_06115 ENOG4105CSP Major Facilitator Superfamily BOC52_06155 ENOG4108D1K outer membrane usher protein BOC52_06180 ENOG4105BZU Histidine kinase BOC52_06185 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_06290 ENOG41090EK ompa motb domain protein BOC52_06305 ENOG4105CW0 outer membrane usher protein BOC52_06310 ENOG4108VEV chaperone BOC52_06365 ENOG4105BZ9 Cytochrome C oxidase, subunit I BOC52_06440 ENOG4107RUE extracellular solute-binding protein family 1 BOC52_06445 ENOG4105D38 putrescine abc transporter BOC52_06450 ENOG4105F38 ABC transporter, permease BOC52_06485 ENOG4105F9F transposase BOC52_06500 ENOG4105HSS phospholipase C BOC52_06535 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_06540 ENOG4105CQZ Histidine kinase BOC52_06545 ENOG4105CSH Transporter BOC52_06560 ENOG4107M1U Histone family protein nucleoid-structuring protein H-NS BOC52_06595 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BOC52_06600 ENOG4105EMN RNA polymerase sigma factor BOC52_06690 ENOG4105D2S major facilitator superfamily BOC52_06695 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BOC52_06700 ENOG4105F2Z 3-oxoadipate enol-lactonase BOC52_06705 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase BOC52_06710 ENOG4107QNJ CoA-transferase subunit B BOC52_06730 ENOG4105EUJ GTP cyclohydrolase i BOC52_06745 ENOG4105D7W serine acetyltransferase BOC52_06795 ENOG4107YZX Universal stress protein BOC52_06800 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BOC52_06805 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) BOC52_06820 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BOC52_06880 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BOC52_06915 ENOG4108TGY Glutathione S-transferase BOC52_06935 ENOG4105EJC lysr family transcriptional regulator BOC52_06940 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BOC52_06965 ENOG4105J7D transcriptional regulator BOC52_06985 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BOC52_07035 ENOG4107QJE Chromosome Partitioning Protein BOC52_07050 ENOG4105K89 arsenate reductase BOC52_07060 ENOG4108WQI RNA Polymerase BOC52_07080 ENOG4105EFQ Two component transcriptional regulator (Winged helix family BOC52_07090 ENOG4105BZU Histidine kinase BOC52_07105 ENOG4105FE1 phytoene synthase BOC52_07115 ENOG4105EWU Squalene--hopene cyclase BOC52_07120 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BOC52_07130 ENOG4107R0W ABC transporter BOC52_07135 ENOG4105E5Q amino acid AbC transporter BOC52_07140 ENOG4105CDA abc transporter atp-binding protein BOC52_07150 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BOC52_07170 ENOG4107EEY synthase BOC52_07185 ENOG4105H3G oxidoreductase BOC52_07190 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BOC52_07230 ENOG4105BZU Histidine kinase BOC52_07285 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BOC52_07310 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BOC52_07320 ENOG4108Z9W Outer membrane porin BOC52_07385 ENOG4108KDI dmso reductase anchor subunit BOC52_07390 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BOC52_07395 ENOG4105DB1 molybdopterin oxidoreductase BOC52_07425 ENOG4105E2B Taurine dioxygenase BOC52_07430 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BOC52_07440 ENOG41061ZR Transcriptional regulator BOC52_07460 ENOG4107Y70 Heat shock protein BOC52_07475 ENOG4105CJW magnesium transporter BOC52_07535 ENOG4108EQM faD-dependent pyridine nucleotide-disulfide oxidoreductase BOC52_07575 ENOG4107R0V Pyruvate dehydrogenase BOC52_07580 ENOG4105CPP Dehydrogenase, E1 component BOC52_07585 ENOG4107QSN dihydrolipoamide acetyltransferase BOC52_07590 ENOG4107QN2 dihydrolipoyl dehydrogenase BOC52_07610 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) BOC52_07645 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BOC52_07660 ENOG4105E33 succinate dehydrogenase BOC52_07665 ENOG4105DJ4 phosphatidylserine decarboxylase BOC52_07680 ENOG4108JJ7 ABC transporter BOC52_07690 ENOG4105CHR reductase BOC52_07695 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BOC52_07700 ENOG4105XA0 heptosyltransferase ii BOC52_07725 ENOG4108JUA Transcriptional regulator BOC52_07740 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_07775 ENOG4105K3G Periplasmic Protein BOC52_07780 ENOG4107JEE Short-chain dehydrogenase reductase Sdr BOC52_07805 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BOC52_07830 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BOC52_07835 ENOG4108UN4 phage SPO1 DNA polymerase-related protein BOC52_07845 ENOG4105ETX regulatoR BOC52_07855 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BOC52_07950 ENOG4108N8X transition metal ion binding BOC52_07955 ENOG4105WEF catalase BOC52_07965 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BOC52_08000 ENOG4105FDF Could be involved in DNA repair (By similarity) BOC52_08005 ENOG4105DQE DNA ligase BOC52_08060 ENOG4105C85 amino acid BOC52_08065 ENOG4108Z9W Outer membrane porin BOC52_08075 ENOG4105CGF Aromatic amino acid aminotransferase BOC52_08085 ENOG4105F7P transcriptional regulator AsnC family BOC52_08240 ENOG4105D22 carbon starvation protein BOC52_08245 ENOG4105VCD cytoplasmic protein BOC52_08265 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BOC52_08290 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BOC52_08295 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BOC52_08300 ENOG4105CKK Glycosyl transferase, family 2 BOC52_08360 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BOC52_08390 ENOG4105DUX Transporter BOC52_08410 ENOG4107QSI ABC, transporter BOC52_08415 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BOC52_08420 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BOC52_08425 ENOG4105C3U ABC transporter BOC52_08430 ENOG4108JQ7 (ABC) transporter BOC52_08435 ENOG4105J5J Outer membrane porin BOC52_08460 ENOG4105CY2 Citrate transporter BOC52_08465 ENOG4108JUA Transcriptional regulator BOC52_08485 ENOG4107M1U Histone family protein nucleoid-structuring protein H-NS BOC52_08495 ENOG4105CD5 CoA-binding domain protein BOC52_08515 ENOG4105ERH Fumarylacetoacetate hydrolase BOC52_08520 ENOG4105DMF Dehydrogenase BOC52_08525 ENOG4105ETT transcriptional Regulator, LysR family BOC52_08535 ENOG4105CSH Transporter BOC52_08555 ENOG4107QI6 Cysteine desulfurase BOC52_08560 ENOG4105C57 major facilitator superfamily BOC52_08570 ENOG4105CR7 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity) BOC52_08585 ENOG4105DND Transcriptional regulator BOC52_08590 ENOG4105BZC d-serine deaminase BOC52_08595 ENOG4105ETT transcriptional Regulator, LysR family BOC52_08600 ENOG4105CHR reductase BOC52_08625 ENOG41061H0 Monooxygenase BOC52_08665 ENOG4106VK6 Flagellar motor protein BOC52_08705 ENOG4108WC9 type VI secretion system effector, hcp1 family BOC52_08725 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_08730 ENOG4105CS6 Rhs element vgr protein BOC52_08845 ENOG4108C33 Resolvase BOC52_08865 ENOG4105ETE Transcriptional regulator (LacI family BOC52_08880 ENOG4108IJ9 (ABC) transporter BOC52_08885 ENOG4105XN3 extracellular solute-binding protein family 1 BOC52_08895 ENOG4105DRS transport system, permease BOC52_08920 ENOG4108YXQ IS66 Orf2 family protein BOC52_08930 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein BOC52_08945 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BOC52_08950 ENOG4105C05 Multifunctional regulator of fatty acid metabolism (By similarity) BOC52_08980 ENOG4105CK2 sodium dicarboxylate symporter BOC52_09010 ENOG4105DFS Conserved Protein BOC52_09040 ENOG4105CNA YD repeat protein BOC52_09135 ENOG4108IQE Amp-dependent synthetase and ligase BOC52_09145 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme BOC52_09160 ENOG4105C1G acyl-Coa dehydrogenase BOC52_09165 ENOG4107QX3 carboxylase BOC52_09170 ENOG4105CHR reductase BOC52_09180 ENOG4105C1G acyl-Coa dehydrogenase BOC52_09185 ENOG4108IG5 Transcriptional regulator BOC52_09200 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BOC52_09205 ENOG4105CVK Glutamate decarboxylase BOC52_09235 ENOG4105CVK Glutamate decarboxylase BOC52_09260 ENOG4105EE5 Membrane protein terC BOC52_09265 ENOG41063Z6 transcriptional regulator, lysR family BOC52_09300 ENOG4107R8N Glycosyl transferase, family 2 BOC52_09330 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BOC52_09355 ENOG4107T3I fad-binding protein BOC52_09365 ENOG4105QV4 Tryptophan halogenase BOC52_09410 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BOC52_09495 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BOC52_09505 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BOC52_09510 ENOG4108RG0 uracil-dna glycosylase BOC52_09515 ENOG4105MP9 class II Aldolase BOC52_09650 ENOG4105BZU Histidine kinase BOC52_09665 ENOG4108J2P Alpha beta hydrolase fold BOC52_09690 ENOG4105JQN Transcriptional regulator BOC52_09720 ENOG4105D9N nucleoside BOC52_09725 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BOC52_09755 ENOG4105KG3 cytidine deaminase BOC52_09765 ENOG4105K3G Periplasmic Protein BOC52_09785 ENOG4107QYA phosphate BOC52_09790 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class BOC52_09805 ENOG41081R2 Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BOC52_09820 ENOG4107WCG it plays a direct role in the translocation of protons across the membrane (By similarity) BOC52_09830 ENOG4108Q71 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) BOC52_09840 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BOC52_09865 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_09875 ENOG4105BZU Histidine kinase BOC52_09880 ENOG4105CMI transporter BOC52_09885 ENOG4105CJ1 ABC, transporter BOC52_09890 ENOG4105D0S secretion protein (HlyD BOC52_09895 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BOC52_09905 ENOG4107YZX Universal stress protein BOC52_09920 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BOC52_09945 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_10025 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BOC52_10035 ENOG4105CHR reductase BOC52_10045 ENOG4105CY0 Metallo-Beta-Lactamase BOC52_10075 ENOG4108IQI permease BOC52_10095 ENOG4105D3W isochorismatase BOC52_10110 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase BOC52_10115 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein BOC52_10120 ENOG4108UKV benzoate 1,2-dioxygenase BOC52_10125 ENOG4105FUY alpha subunit BOC52_10135 ENOG4108KB2 LysR family Transcriptional regulator BOC52_10150 ENOG4108R6W Transcriptional regulator, ARAC family BOC52_10155 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BOC52_10175 ENOG4105CCU oxidase (Subunit III) BOC52_10180 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BOC52_10230 ENOG4105K59 histidine triad (HIT) protein BOC52_10235 ENOG4107RZC phospholipase d BOC52_10255 ENOG4106BRA Membrane BOC52_10260 ENOG4105EEQ Na H antiporter BOC52_10265 ENOG4105C7K acetolactate synthase BOC52_10285 ENOG4105ECM Sensor protein basS pmrB BOC52_10290 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BOC52_10300 ENOG4108KTQ Methyltransferase BOC52_10310 ENOG4105CBS Chea signal transduction histidine kinase BOC52_10315 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BOC52_10325 ENOG4107R4J Chloride channel BOC52_10370 ENOG4108JJ7 ABC transporter BOC52_10380 ENOG4105EZR dyp-type peroxidase family protein BOC52_10435 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BOC52_10455 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BOC52_10475 ENOG4107ENK receptor BOC52_10485 ENOG4105IPI Membrane BOC52_10515 ENOG4105GRZ Ycii-related protein BOC52_10520 ENOG4105GRZ Ycii-related protein BOC52_10530 ENOG4105CHP RNA polymerase BOC52_10545 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BOC52_10550 ENOG4108RAC Rubrerythrin BOC52_10555 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BOC52_10580 ENOG4105D3Q Sugar transferase BOC52_10585 ENOG4105C6Y Udp-glucose 6-dehydrogenase BOC52_10595 ENOG4105DAY polysaccharide export protein BOC52_10620 ENOG4107RJ7 Glycosyl transferase (Group 1 BOC52_10625 ENOG4105E2K Glycosyl transferase (Group 1 BOC52_10635 ENOG4108V1T peptidylprolyl cis-trans isomerase BOC52_10660 ENOG4108R1E Serine threonine protein phosphatase 1 BOC52_10700 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_10720 ENOG4105JSC dimethylmenaquinone methyltransferase BOC52_10725 ENOG4105CM2 brancheD-chain amino acid aminotransferase BOC52_10785 ENOG4105DMF Dehydrogenase BOC52_10805 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BOC52_10810 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BOC52_10815 ENOG4105C37 (CBS) domain BOC52_10830 ENOG4105CBN LysR family transcriptional regulator BOC52_10845 ENOG4105F4R Transcriptional regulator mode BOC52_10855 ENOG4108IJ6 ABC transporter BOC52_10860 ENOG4105E0C molybdate abc transporter BOC52_10865 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BOC52_10875 ENOG4105MH5 phosphoesterase PA-phosphatase related protein BOC52_10890 ENOG4108ZHJ Organic hydroperoxide resistance protein BOC52_10895 ENOG4105K56 Transcriptional regulator BOC52_10920 ENOG4105FYV Amp nucleosidase BOC52_10930 ENOG4105ED4 portal protein BOC52_10955 ENOG4105EWC Purine nucleoside phosphorylase BOC52_10975 ENOG4108URH decarboxylase BOC52_10980 ENOG4105C2M dna polymerase I BOC52_10985 ENOG4105CEP NADH dehydrogenase BOC52_11000 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BOC52_11030 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BOC52_11045 ENOG4105CBX hi0933 family BOC52_11095 ENOG4105ETS cytosine purines uracil thiamine allantoin BOC52_11100 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BOC52_11115 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BOC52_11130 ENOG4108K5P (LipO)protein BOC52_11140 ENOG4105CPW cytochrome b561 BOC52_11150 ENOG4105E0K tonB-dependent siderophore receptor BOC52_11175 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BOC52_11185 ENOG4105F38 ABC transporter, permease BOC52_11190 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BOC52_11250 ENOG4108YH7 hemolysin BOC52_11255 ENOG4108QZZ filamentous hemagglutinin BOC52_11260 ENOG4107QM5 aconitate hydratase BOC52_11265 ENOG4105DXD 2-methylcitrate dehydratase BOC52_11285 ENOG4105FDP GntR family transcriptional regulator BOC52_11295 ENOG410612Q succinate dehydrogenase (cytochrome b-556 subunit) BOC52_11305 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) BOC52_11310 ENOG4105E33 succinate dehydrogenase BOC52_11315 ENOG41060IS Flavinator of succinate dehydrogenase BOC52_11320 ENOG4105BZN citrate synthase BOC52_11340 ENOG41072TH Protein of unknown function (DUF1479) BOC52_11345 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BOC52_11350 ENOG4108YXU transcriptional regulator AsnC family BOC52_11365 ENOG4105CPU Monooxygenase BOC52_11390 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BOC52_11400 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BOC52_11415 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BOC52_11420 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BOC52_11435 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BOC52_11440 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BOC52_11455 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BOC52_11460 ENOG4105C28 cystathionine BOC52_11475 ENOG4107TXM Nad-dependent epimerase dehydratase BOC52_11480 ENOG4105C0K Gdp-mannose 4,6-dehydratase BOC52_11485 ENOG4105EXC Acyl-transferase BOC52_11500 ENOG4108MX3 Polysaccharide Biosynthesis Protein BOC52_11505 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) BOC52_11525 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BOC52_11535 ENOG4105EXC Acyl-transferase BOC52_11560 ENOG4108Z9W Outer membrane porin BOC52_11565 ENOG4107S2Z UPF0761 membrane protein BOC52_11585 ENOG4105E5N succinylglutamate desuccinylase aspartoacylase BOC52_11605 ENOG4105EAB amino acid AbC transporter BOC52_11615 ENOG4105DEN Luciferase family BOC52_11625 ENOG4105CDA abc transporter atp-binding protein BOC52_11635 ENOG4105EAB amino acid AbC transporter BOC52_11655 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BOC52_11660 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BOC52_11665 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BOC52_11670 ENOG4108MG3 formate dehydrogenase BOC52_11675 ENOG4105F46 Necessary for formate dehydrogenase activity (By similarity) BOC52_11680 ENOG4105C1Y Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity) BOC52_11685 ENOG4105EM7 Selenocysteine-specific translation elongation factor BOC52_11830 ENOG4107V6I Cytosine-specific methyltransferase BOC52_11885 ENOG4108ZQS transposase BOC52_11890 ENOG4108MVM Transposase BOC52_12105 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BOC52_12115 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BOC52_12190 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_12200 ENOG4105BZU Histidine kinase BOC52_12210 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_12215 ENOG4105JQN Transcriptional regulator BOC52_12225 ENOG4105C5Q Transcriptional regulator BOC52_12235 ENOG4105DJG MaoC domain protein dehydratase BOC52_12240 ENOG4105CYC Transferase BOC52_12245 ENOG4105C7K acetolactate synthase BOC52_12310 ENOG4108TN6 type iii secretion BOC52_12320 ENOG4108JIR Flagellum-specific ATP synthase BOC52_12335 ENOG4107Y59 type iii secretion BOC52_12450 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BOC52_12460 ENOG4105CZX twitching motility protein BOC52_12490 ENOG4107QHF type ii secretion system protein e BOC52_12515 ENOG4105K44 type iii secretion BOC52_12570 ENOG4105CYW agmatinase BOC52_12590 ENOG4105CAF HipA N-terminal domain protein BOC52_12615 ENOG4107EEX Cellulose synthase regulator protein BOC52_12620 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BOC52_12625 ENOG4105EJG cellulose synthase BOC52_12645 ENOG4107QZ7 Cellulose synthase catalytic subunit BOC52_12650 ENOG4105D1V cellulose synthase operon protein YhjU BOC52_12660 ENOG4105E2B Taurine dioxygenase BOC52_12670 ENOG4106FTQ Taurine ABC transporter, periplasmic BOC52_12675 ENOG4108IY8 ABC, transporter BOC52_12680 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BOC52_12690 ENOG4105NNS Autoinducer synthesis protein BOC52_12705 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_12725 ENOG4105CJ3 phosphate transporter BOC52_12735 ENOG4108ZRZ Transcriptional regulator (AsnC family) BOC52_12740 ENOG4105CCF Lysine exporter protein (Lyse ygga) BOC52_12775 ENOG4105CSH Transporter BOC52_12855 ENOG4108RBT type iii secretion BOC52_12865 ENOG4105Y7Q type iii secretion BOC52_12870 ENOG4108RC9 Type III secretion system protein BOC52_12880 ENOG4105YY8 Transcriptional regulator BOC52_12885 ENOG4105K44 type iii secretion BOC52_12890 ENOG4108N8R Invasion protein BOC52_12895 ENOG4108HR8 type iii secretion BOC52_12905 ENOG4108JIR Flagellum-specific ATP synthase BOC52_12925 ENOG41075IY surface presentation of antigens protein SpaP BOC52_12935 ENOG4108TN6 type iii secretion BOC52_12960 ENOG4107M1U Histone family protein nucleoid-structuring protein H-NS BOC52_12975 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BOC52_12980 ENOG4105FTC Lytic transglycosylase catalytic BOC52_13010 ENOG4105WH1 Two component transcriptional regulator luxr family BOC52_13140 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_13215 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BOC52_13255 ENOG4105EQN UPF0261 protein BOC52_13295 ENOG4105CPQ Dehydrogenase BOC52_13300 ENOG4105CXK mandelate racemase muconate lactonizing BOC52_13310 ENOG4105DEI Mannitol dehydrogenase BOC52_13320 ENOG4108I5G Major Facilitator superfamily BOC52_13330 ENOG4105E98 transcriptional regulator DeoR family BOC52_13360 ENOG4105CJP fad dependent oxidoreductase BOC52_13375 ENOG4105ETT transcriptional Regulator, LysR family BOC52_13390 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BOC52_13395 ENOG4105C26 Dehydrogenase BOC52_13400 ENOG4105CJ2 (LipO)protein BOC52_13425 ENOG4105XJC Two component transcriptional regulator (Winged helix family BOC52_13445 ENOG4105C54 Major Facilitator superfamily BOC52_13485 ENOG4105FUY alpha subunit BOC52_13500 ENOG4105CEI nitrite reductase BOC52_13530 ENOG4105C1G acyl-Coa dehydrogenase BOC52_13535 ENOG4107QX3 carboxylase BOC52_13600 ENOG4105D6J arsenicaL-resistance protein BOC52_13615 ENOG41085FC arsR family transcriptional regulator BOC52_13635 ENOG4108YYH Nadph-dependent fmn reductase BOC52_13650 ENOG4108IJ7 Glycine betaine BOC52_13660 ENOG4105ECQ AraC Family Transcriptional Regulator BOC52_13700 ENOG4105EXW epimerase dehydratase BOC52_13705 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BOC52_13710 ENOG4105CSP Major Facilitator Superfamily BOC52_13715 ENOG4105FB2 class II Aldolase BOC52_13725 ENOG4105ZXK Dehydrogenase BOC52_13730 ENOG4107YCY Transcriptional regulator BOC52_13790 ENOG41083GP type iii secretion BOC52_13830 ENOG4107Y59 type iii secretion BOC52_13845 ENOG4108JIR Flagellum-specific ATP synthase BOC52_13910 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BOC52_13940 ENOG4105KT7 mgtC SapB transporter BOC52_13955 ENOG4105C4M (Ubiquinol oxidase) subunit I BOC52_13960 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BOC52_14000 ENOG4105ECQ AraC Family Transcriptional Regulator BOC52_14005 ENOG4105EJQ L-serine dehydratase BOC52_14020 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BOC52_14060 ENOG4105VEQ Cold shock protein BOC52_14090 ENOG4105C5I Dehydrogenase BOC52_14105 ENOG4105BZU Histidine kinase BOC52_14175 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_14180 ENOG4105H63 Glycosyl transferase, family 2 BOC52_14195 ENOG4105CW7 secretion protein, HlyD family BOC52_14225 ENOG4105D7W serine acetyltransferase BOC52_14235 ENOG4105ESN nucleotide-binding protein BOC52_14240 ENOG4105C9B Cysteine desulfurase BOC52_14245 ENOG4105CPW cytochrome b561 BOC52_14255 ENOG41080HT Transcriptional regulator, arsr family BOC52_14260 ENOG4105MD1 YeeE YedE family protein BOC52_14270 ENOG4108Z24 l-2,4-diaminobutyric acid acetyltransferase BOC52_14290 ENOG4105JQZ Methyltransferase BOC52_14310 ENOG4107RGD Major Facilitator superfamily BOC52_14315 ENOG4105FDP GntR family transcriptional regulator BOC52_14330 ENOG4105EW9 transcriptional regulator AsnC family BOC52_14345 ENOG4105E7U AraC family transcriptional regulator BOC52_14370 ENOG4105CQB FAD linked oxidase domain protein BOC52_14380 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BOC52_14420 ENOG4107S1E Beta-lactamase BOC52_14425 ENOG4105C94 Transporter BOC52_14440 ENOG4108JQ6 ABC transporter BOC52_14450 ENOG4105DEF Extracellular solute-binding protein, family 5 BOC52_14455 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BOC52_14460 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BOC52_14485 ENOG4105DDW LysR family Transcriptional regulator BOC52_14510 ENOG4108VQJ O-methyltransferase BOC52_14515 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BOC52_14535 ENOG4105DVH amino acid BOC52_14545 ENOG4107QRT dEAD DEAH box helicase BOC52_14565 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BOC52_14575 ENOG4105DFG type I secretion outer membrane protein BOC52_14590 ENOG4108JJA ABC, transporter BOC52_14615 ENOG4105CSR polyphosphate kinase 2 BOC52_14630 ENOG4105C7B Threonine dehydratase BOC52_14660 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BOC52_14680 ENOG4107RCI amp-dependent synthetase and ligase BOC52_14720 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_14780 ENOG4108I6A alcohol dehydrogenase BOC52_14785 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BOC52_14815 ENOG4105CHR reductase BOC52_14820 ENOG4105CBN LysR family transcriptional regulator BOC52_14835 ENOG4105DUM transcriptional regulator, lysR family BOC52_14840 ENOG4105CSH Transporter BOC52_14845 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BOC52_14880 ENOG4105EUJ GTP cyclohydrolase i BOC52_14900 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BOC52_14915 ENOG4107QZF nitrite reductase NADPH large subunit BOC52_14920 ENOG4105WZK nitrite reductase NADPH small subunit BOC52_14925 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BOC52_14940 ENOG4105CJN penicillin-binding protein BOC52_14945 ENOG4105DZ1 carboxypeptidase BOC52_14960 ENOG4105CMG Carbohydrate kinase BOC52_14970 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BOC52_14975 ENOG4105CPQ Dehydrogenase BOC52_15010 ENOG4106UW1 Major Facilitator superfamily BOC52_15015 ENOG4105MVE transcriptional regulator BOC52_15070 ENOG4105CKD glutathione-regulated potassium-efflux system protein BOC52_15135 ENOG41080BE Methyl-accepting chemotaxis sensory transducer BOC52_15155 ENOG4108UB3 Thiamine monophosphate BOC52_15160 ENOG4105CSH Transporter BOC52_15215 ENOG4105D5G Transposase BOC52_15240 ENOG4105CXT aspartate transcarbamylase BOC52_15260 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BOC52_15320 ENOG4105DEN Luciferase family BOC52_15380 ENOG4105NNS Autoinducer synthesis protein BOC52_15400 ENOG4105VJY transcriptional regulator BOC52_15410 ENOG4105DGW oligopeptidase A BOC52_15415 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_15480 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BOC52_15550 ENOG4105WH1 Two component transcriptional regulator luxr family BOC52_15555 ENOG4105BZU Histidine kinase BOC52_15565 ENOG4105CRU nitrate reductase, alpha subunit BOC52_15570 ENOG4108IUE nitrate reductase beta subunit BOC52_15575 ENOG4105R3A Nitrate reductase BOC52_15580 ENOG41076YT nitrate reductase, gamma subunit BOC52_15585 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BOC52_15605 ENOG4105IH7 synthase BOC52_15625 ENOG4108JPZ Monovalent cation H antiporter subunit D BOC52_15630 ENOG4107TDF Formate hydrogenlyase subunit 4 BOC52_15640 ENOG4108JPZ Monovalent cation H antiporter subunit D BOC52_15645 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BOC52_15650 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit BOC52_15705 ENOG4105U3E Transcriptional regulator BOC52_15710 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BOC52_15755 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BOC52_15760 ENOG4105E46 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process BOC52_15775 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BOC52_15785 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BOC52_15790 ENOG4105BZS acriflavin resistance protein BOC52_15795 ENOG4105ENT Efflux transporter rnd family, mfp subunit BOC52_15835 ENOG4105D5Q Arginine ornithine antiporter BOC52_15865 ENOG41062IR nudix hydrolase BOC52_15885 ENOG4105DWF phosphomethylpyrimidine kinase BOC52_15960 ENOG4105CFG Acts as a chaperone (By similarity) BOC52_16000 ENOG4105DCF alanine dehydrogenase BOC52_16085 ENOG4105C54 Major Facilitator superfamily BOC52_16095 ENOG4105D2B acyl-CoA dehydrogenase BOC52_16130 ENOG4105C2J ABC transporter BOC52_16135 ENOG4105CNN ABC, transporter BOC52_16140 ENOG4105CNN ABC, transporter BOC52_16150 ENOG4108S3W Anti-feci sigma factor, fecr BOC52_16155 ENOG4108SF5 RNA Polymerase BOC52_16175 ENOG4108YYC ycei family BOC52_16205 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BOC52_16240 ENOG4105CR8 Transcriptional regulator BOC52_16260 ENOG4105CMQ Chloride channel BOC52_16280 ENOG4107SQU synthase BOC52_16290 ENOG4107SQU synthase BOC52_16295 ENOG4105C0W non-ribosomal peptide synthetase BOC52_16315 ENOG4108Z66 YbaK ebsC protein BOC52_16320 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_16325 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BOC52_16335 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BOC52_16340 ENOG4105K8N protein family UPF0079, ATPase BOC52_16345 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BOC52_16350 ENOG4108594 Permease of the drug metabolite transporter BOC52_16355 ENOG4105EUB pirin domain protein BOC52_16360 ENOG4105K63 Thioredoxin BOC52_16370 ENOG4105CUZ uba thif-type nad fad binding protein BOC52_16380 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BOC52_16395 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BOC52_16410 ENOG4105F7P transcriptional regulator AsnC family BOC52_16430 ENOG4105D2S major facilitator superfamily BOC52_16440 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BOC52_16450 ENOG4105FP9 thiamine pyrophosphate BOC52_16455 ENOG4105DDW LysR family Transcriptional regulator BOC52_16460 ENOG4105DEI Mannitol dehydrogenase BOC52_16465 ENOG4105CMG Carbohydrate kinase BOC52_16470 ENOG4105DKT Transcriptional regulator BOC52_16480 ENOG4107S1E Beta-lactamase BOC52_16485 ENOG4105CC0 LysR family Transcriptional regulator BOC52_16500 ENOG4108IJ9 (ABC) transporter BOC52_16505 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BOC52_16515 ENOG4105S9S Binding-protein-dependent transport systems, inner membrane component BOC52_16525 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BOC52_16530 ENOG4107UEK pfkb domain protein BOC52_16535 ENOG4105CHR reductase BOC52_16540 ENOG4105MYN Zinc uptake regulation protein BOC52_16550 ENOG4105DIK (ABC) transporter BOC52_16555 ENOG4105CC5 ABC transporter BOC52_16560 ENOG4105C4W S-formylglutathione hydrolase BOC52_16565 ENOG4107QPD alcohol dehydrogenase BOC52_16570 ENOG4105ECQ AraC Family Transcriptional Regulator BOC52_16575 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BOC52_16580 ENOG4105C2W permease BOC52_16590 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BOC52_16595 ENOG4105BZS acriflavin resistance protein BOC52_16600 ENOG4105C1P efflux transporter, rnd family, mfp subunit BOC52_16630 ENOG4105C0H protease BOC52_16645 ENOG4105XJC Two component transcriptional regulator (Winged helix family BOC52_16680 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BOC52_16685 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BOC52_16690 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BOC52_16695 ENOG4105C8V SAICAR synthetase BOC52_16705 ENOG4105CA9 Pyruvate kinase BOC52_16715 ENOG4105BZA Phosphoglycerate kinase BOC52_16730 ENOG4105CM2 brancheD-chain amino acid aminotransferase BOC52_16740 ENOG4105XA0 heptosyltransferase ii BOC52_16750 ENOG4105DNZ Alpha Beta Hydrolase BOC52_16760 ENOG4105ERG peptidase m48, ste24p BOC52_16790 ENOG4108YSG O-Antigen polymerase BOC52_16795 ENOG4105KHS type IV fimbrial pilin protein BOC52_16800 ENOG4108ZCF integral membrane protein BOC52_16805 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BOC52_16820 ENOG4108004 Modulates RecA activity (By similarity) BOC52_16825 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BOC52_16835 ENOG4105DHQ Histidine kinase BOC52_16840 ENOG4105CSH Transporter BOC52_16860 ENOG4105CMM transposase BOC52_16895 ENOG4105BZU Histidine kinase BOC52_16900 ENOG4105CBN LysR family transcriptional regulator BOC52_16945 ENOG4105DIA mandelate racemase muconate lactonizing BOC52_16955 ENOG4105Z4T Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity) BOC52_16960 ENOG4105BZ9 Cytochrome C oxidase, subunit I BOC52_17020 ENOG4108IY8 ABC, transporter BOC52_17045 ENOG4105CR7 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity) BOC52_17050 ENOG4105EJC lysr family transcriptional regulator BOC52_17055 ENOG4105CK2 sodium dicarboxylate symporter BOC52_17070 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BOC52_17090 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_17095 ENOG4105BZU Histidine kinase BOC52_17115 ENOG4105CXK mandelate racemase muconate lactonizing BOC52_17145 ENOG4105C1J atp-dependent rna helicase BOC52_17160 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BOC52_17165 ENOG4105E98 transcriptional regulator DeoR family BOC52_17185 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BOC52_17190 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BOC52_17195 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BOC52_17210 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BOC52_17215 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BOC52_17220 ENOG4105CAQ asparagine synthetase BOC52_17235 ENOG4107YBY Hydrolase BOC52_17245 ENOG4108JCI Transcriptional regulator BOC52_17250 ENOG4105F27 Major Facilitator BOC52_17255 ENOG4105EJC lysr family transcriptional regulator BOC52_17270 ENOG4105C9A Phoh family BOC52_17285 ENOG4108NH8 Cation transport protein BOC52_17290 ENOG4108JU5 Magnesium and cobalt efflux protein BOC52_17295 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BOC52_17305 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BOC52_17310 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BOC52_17315 ENOG4105E9Q Acyl-transferase BOC52_17340 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BOC52_17350 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) BOC52_17355 ENOG4105EHM Aminoglycoside phosphotransferase BOC52_17360 ENOG4108S0S Nucleotidyl transferase BOC52_17370 ENOG4108JJ7 ABC transporter BOC52_17380 ENOG4105NAU thioesterase Superfamily protein BOC52_17390 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BOC52_17395 ENOG4105E39 Enoyl-CoA hydratase BOC52_17400 ENOG4105CHU acetyl-coa acetyltransferase BOC52_17410 ENOG4105CSU acyl-Coa dehydrogenase BOC52_17420 ENOG4105DZQ phospholipase D Transphosphatidylase BOC52_17425 ENOG4108TIT dATP pyrophosphohydrolase BOC52_17500 ENOG4105C7B Threonine dehydratase BOC52_17510 ENOG4105KME endoribonuclease L-psp BOC52_17545 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_17580 ENOG4108TJN glycosyl transferase group 1 BOC52_17585 ENOG4105DAY polysaccharide export protein BOC52_17590 ENOG4105D3Q Sugar transferase BOC52_17610 ENOG410609C Acyl carrier protein BOC52_17640 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_17680 ENOG4105BZU Histidine kinase BOC52_17690 ENOG4105MP9 class II Aldolase BOC52_17710 ENOG4105D9P serine threonine protein kinase BOC52_17750 ENOG4105EAH synthase BOC52_17840 ENOG4107RDB Major Facilitator BOC52_17845 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BOC52_17890 ENOG4105C2X Arabinose 5-phosphate isomerase BOC52_17895 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BOC52_17910 ENOG4108IUZ ABC transporter BOC52_17915 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BOC52_17925 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BOC52_17930 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BOC52_17940 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BOC52_17955 ENOG4105CEN a g-specific adenine glycosylase BOC52_17970 ENOG41081V9 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) BOC52_17985 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BOC52_18005 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BOC52_18020 ENOG4106H78 methyltransferase BOC52_18030 ENOG4108RXX maleylacetoacetate isomerase BOC52_18040 ENOG4108IFG nitrite reductase, (NAD(P)H) BOC52_18050 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BOC52_18055 ENOG4108MTB glycosyl transferase family BOC52_18070 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) BOC52_18080 ENOG41061N2 exported protein BOC52_18085 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BOC52_18095 ENOG4105C4M (Ubiquinol oxidase) subunit I BOC52_18100 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BOC52_18125 ENOG4105CI1 PTS System BOC52_18130 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BOC52_18135 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BOC52_18140 ENOG4105CE4 GlcNAc 6-P deacetylase BOC52_18145 ENOG4105FDP GntR family transcriptional regulator BOC52_18155 ENOG4106NZI LysR family Transcriptional regulator BOC52_18200 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_18210 ENOG4105CSU acyl-Coa dehydrogenase BOC52_18220 ENOG4105DVA methyltransferase BOC52_18230 ENOG4107T0D ABC, transporter BOC52_18255 ENOG4105EQ0 Major Facilitator superfamily BOC52_18265 ENOG4105C0B DNA polymerase III (alpha subunit) BOC52_18275 ENOG4108ZD2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity) BOC52_18280 ENOG4105D5T phosphonate abc transporter BOC52_18300 ENOG4105D01 (LipO)protein BOC52_18310 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_18330 ENOG4107TQK Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity) BOC52_18350 ENOG4107QS1 Cytochrome C Oxidase, Subunit III BOC52_18360 ENOG4105FT1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) BOC52_18370 ENOG4105BZ9 Cytochrome C oxidase, subunit I BOC52_18375 ENOG4105CV4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity) BOC52_18385 ENOG4106T9E Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BOC52_18390 ENOG4105MJ2 Competence protein BOC52_18400 ENOG4108UVJ appr-1-p processing domain protein BOC52_18420 ENOG4107YZP Rhodanese domain protein BOC52_18430 ENOG4105CN1 protease BOC52_18435 ENOG4105D06 uba thif-type nad fad binding protein BOC52_18445 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BOC52_18450 ENOG41080Z8 PHOSPHOCARRIER protein BOC52_18460 ENOG4105D7Z glutathione synthase BOC52_18470 ENOG4105BZU Histidine kinase BOC52_18475 ENOG4108YZA Nitrogen regulatory protein pii BOC52_18480 ENOG4105W0Z cytoplasmic protein BOC52_18485 ENOG4105C0P Mg chelatase subunit ChlI BOC52_18520 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BOC52_18525 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_18540 ENOG4107QN1 sodium solute BOC52_18550 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BOC52_18555 ENOG4105C1G acyl-Coa dehydrogenase BOC52_18560 ENOG4105X7H acyl-CoA dehydrogenase BOC52_18565 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BOC52_18570 ENOG4105CBN LysR family transcriptional regulator BOC52_18580 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BOC52_18605 ENOG4105ETT transcriptional Regulator, LysR family BOC52_18610 ENOG4108Z43 UPF0250 protein BOC52_18615 ENOG4105F0I Aminotransferase BOC52_18620 ENOG4105DZ1 carboxypeptidase BOC52_18655 ENOG4105DHJ ABC, transporter BOC52_18665 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BOC52_18680 ENOG4108194 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) BOC52_18745 ENOG4105DFP Integrase BOC52_18750 ENOG4107Z67 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) BOC52_18775 ENOG4105CGU Enoyl-CoA hydratase BOC52_18805 ENOG4105C3R Methionine synthase BOC52_18810 ENOG4105C3R Methionine synthase BOC52_18835 ENOG4105EMU Dehydrogenase BOC52_18840 ENOG4105CHR reductase BOC52_18855 ENOG4105CHU acetyl-coa acetyltransferase BOC52_18860 ENOG4105DEF Extracellular solute-binding protein, family 5 BOC52_18865 ENOG4105C5H ABC transporter BOC52_18885 ENOG41077A9 carbonic anhydrase BOC52_18890 ENOG4105CHU acetyl-coa acetyltransferase BOC52_18900 ENOG4105K5B UPF0225 protein BOC52_18920 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BOC52_18950 ENOG4105G6Z alkaline phosphatase BOC52_18960 ENOG4108KMM Diguanylate cyclase BOC52_18965 ENOG4105EEQ Na H antiporter BOC52_18995 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BOC52_19040 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BOC52_19085 ENOG4105EW9 transcriptional regulator AsnC family BOC52_19115 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase BOC52_19120 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BOC52_19140 ENOG4105EW9 transcriptional regulator AsnC family BOC52_19145 ENOG4105EBM Alpha Beta Hydrolase Fold protein BOC52_19160 ENOG4105CC0 LysR family Transcriptional regulator BOC52_19165 ENOG4108Z9W Outer membrane porin BOC52_19175 ENOG4105DHU Bile acid BOC52_19185 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_19190 ENOG4105ETE Transcriptional regulator (LacI family BOC52_19200 ENOG4105D7K pfkb domain protein BOC52_19245 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BOC52_19250 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BOC52_19265 ENOG4108IJF Heavy metal efflux pump, CzcA BOC52_19270 ENOG4105EP1 Efflux transporter rnd family, mfp subunit BOC52_19290 ENOG4105HA9 of methanol dehydrogenase type BOC52_19295 ENOG4108V0P LemA family BOC52_19420 ENOG4108Z9W Outer membrane porin BOC52_19435 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BOC52_19460 ENOG4105ETT transcriptional Regulator, LysR family BOC52_19470 ENOG4105C2W permease BOC52_19480 ENOG4105DTJ flagellar hook-associated protein BOC52_19485 ENOG4105E1Q flagellar hook-associated protein BOC52_19490 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) BOC52_19495 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BOC52_19500 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BOC52_19505 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BOC52_19510 ENOG4105CGA flagellar basal-body rod protein FlgG BOC52_19515 ENOG4108KPB Flagellar basal-body rod protein FlgF BOC52_19520 ENOG4105BZE flagellar hook protein, FlgE BOC52_19525 ENOG4105W00 Flagellar hook capping protein BOC52_19530 ENOG4108ZC9 flagellar basal-body rod protein flgc BOC52_19535 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BOC52_19540 ENOG4105CKS Flagella basal body P-ring formation protein flgA BOC52_19545 ENOG4105M9M anti-sigma28 factor FlgM BOC52_19585 ENOG4107SC1 transglycosylase BOC52_19590 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BOC52_19600 ENOG4105P4J Allophanate hydrolase, subunit 1 BOC52_19605 ENOG4107R7A Allophanate hydrolase subunit 2 BOC52_19610 ENOG4105E7W lamb ycsf family protein BOC52_19640 ENOG4108JQ7 (ABC) transporter BOC52_19645 ENOG4105C3U ABC transporter BOC52_19650 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BOC52_19655 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BOC52_19660 ENOG4105DEF Extracellular solute-binding protein, family 5 BOC52_19670 ENOG4105CSH Transporter BOC52_19675 ENOG4105VMH Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria (By similarity) BOC52_19680 ENOG4105D5U fad dependent oxidoreductase BOC52_19700 ENOG4105X23 Endonuclease Exonuclease phosphatase BOC52_19710 ENOG4105DP0 ferredoxin-NADP reductase BOC52_19720 ENOG4105WH1 Two component transcriptional regulator luxr family BOC52_19725 ENOG4105CUB amino acid BOC52_19740 ENOG4105D00 flagellar biosynthetic protein flhB BOC52_19755 ENOG4105MQ3 flagellar protein FliS BOC52_19765 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BOC52_19770 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BOC52_19775 ENOG41090PJ Flagellar assembly protein BOC52_19800 ENOG4105CSU acyl-Coa dehydrogenase BOC52_19805 ENOG4107RGH Aldehyde dehydrogenase BOC52_19815 ENOG4105E27 serine threonine protein kinase BOC52_19825 ENOG4105D94 Major Facilitator Superfamily BOC52_19835 ENOG4108594 Permease of the drug metabolite transporter BOC52_19845 ENOG4105CPC Aldo Keto reductase BOC52_19875 ENOG4105D1S lipid A biosynthesis BOC52_19890 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BOC52_19900 ENOG4105CKI cobalamin synthesis protein BOC52_19910 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BOC52_19920 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BOC52_19930 ENOG4108UYB regulatoR BOC52_19935 ENOG4105TX3 Histidine kinase BOC52_19955 ENOG4105EC0 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity) BOC52_19970 ENOG4105EYM Major Facilitator superfamily BOC52_19980 ENOG4105CF7 AraC family transcriptional regulator BOC52_19985 ENOG4105DQ4 alcohol dehydrogenase BOC52_19995 ENOG4105CGK Exodeoxyribonuclease III BOC52_20000 ENOG4105CSR polyphosphate kinase 2 BOC52_20020 ENOG4105DFF Rod shape-determining protein mreb BOC52_20035 ENOG4105CJN penicillin-binding protein BOC52_20040 ENOG4105CNI cell division protein FtsW BOC52_20105 ENOG4105ED4 portal protein BOC52_20350 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_20355 ENOG4105ES5 Histidine kinase BOC52_20365 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BOC52_20380 ENOG4108NIW Leucine export protein LeuE BOC52_20395 ENOG4105C79 DNA protecting protein DprA BOC52_20405 ENOG4105C9U ATP-dependent DNA helicase RecQ BOC52_20410 ENOG4105CC0 LysR family Transcriptional regulator BOC52_20415 ENOG4105C5I Dehydrogenase BOC52_20445 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BOC52_20450 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein BOC52_20455 ENOG4105E5H Transposase BOC52_20460 ENOG4108YXQ IS66 Orf2 family protein BOC52_20495 ENOG4105EJC lysr family transcriptional regulator BOC52_20525 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BOC52_20540 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BOC52_20555 ENOG4108VWS Yaeq family BOC52_20570 ENOG4108MK9 spermidine N(1)-acetyltransferase BOC52_20655 ENOG4105DFP Integrase BOC52_20695 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BOC52_20705 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BOC52_20735 ENOG4105FA0 parb-like partition protein BOC52_20760 ENOG4107VGR Catalase BOC52_20810 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BOC52_20815 ENOG4105CHU acetyl-coa acetyltransferase BOC52_20825 ENOG4105C1G acyl-Coa dehydrogenase BOC52_20855 ENOG4105K7K Transcriptional regulator BOC52_20900 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BOC52_20905 ENOG4105C0Z ABC transporter BOC52_20915 ENOG4108IV0 ABC, transporter BOC52_20930 ENOG4108Z9W Outer membrane porin BOC52_20955 ENOG4108Z9W Outer membrane porin BOC52_20970 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BOC52_20980 ENOG4105D2X ABC transporter substrate-binding protein BOC52_20990 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BOC52_20995 ENOG4108Z4X TRANSCRIPTIONal BOC52_21000 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BOC52_21005 ENOG4105VS8 Flagellar biosynthetic protein fliq BOC52_21010 ENOG4105CN7 Flagellar biosynthetic protein FliP BOC52_21020 ENOG4105DD5 Flagellar motor switch protein BOC52_21025 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BOC52_21040 ENOG41067MG lrgb family BOC52_21050 ENOG4105CMU LysR family (Transcriptional regulator BOC52_21055 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_21060 ENOG4105K56 Transcriptional regulator BOC52_21070 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BOC52_21090 ENOG4108RTD type II secretion system protein K BOC52_21100 ENOG4105X5Z General secretion pathway protein I BOC52_21105 ENOG41069X0 general secretion pathway protein h BOC52_21110 ENOG4108VAU general secretion pathway protein G BOC52_21120 ENOG4105D7Q type ii secretion system BOC52_21125 ENOG4107QHF type ii secretion system protein e BOC52_21145 ENOG4105CKI cobalamin synthesis protein BOC52_21190 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BOC52_21195 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BOC52_21215 ENOG4105DHQ Histidine kinase BOC52_21235 ENOG4105KZX Pterin carbinolamine dehydratase BOC52_21240 ENOG4105MIR Phenylalanine 4-monooxygenase BOC52_21245 ENOG4108ZRZ Transcriptional regulator (AsnC family) BOC52_21260 ENOG4105CN8 Transcriptional regulator BOC52_21265 ENOG4105C26 Dehydrogenase BOC52_21285 ENOG4105C0Z ABC transporter BOC52_21290 ENOG4108IV0 ABC, transporter BOC52_21300 ENOG4105C32 Amino acid ABC transporter (Permease) BOC52_21325 ENOG4105C0Z ABC transporter BOC52_21330 ENOG4108IV0 ABC, transporter BOC52_21340 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) BOC52_21345 ENOG4107QJE Chromosome Partitioning Protein BOC52_21350 ENOG4105FA0 parb-like partition protein BOC52_21355 ENOG4105F4P )-transporter BOC52_21365 ENOG4107RAZ it plays a direct role in the translocation of protons across the membrane (By similarity) BOC52_21370 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BOC52_21405 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_21420 ENOG4105K4P CoA-binding domain protein BOC52_21425 ENOG4105F87 Dehydratase BOC52_21440 ENOG4105C25 Primosomal protein n' BOC52_21460 ENOG4105C26 Dehydrogenase BOC52_21480 ENOG4105CSU acyl-Coa dehydrogenase BOC52_21500 ENOG4105CHM Aminotransferase BOC52_21505 ENOG4105E89 ABC transporter BOC52_21515 ENOG4105CQB FAD linked oxidase domain protein BOC52_21525 ENOG4105W1Y Transcriptional regulator BOC52_21570 ENOG4105DVH amino acid BOC52_21575 ENOG4105CPD ethanolamine ammonia-lyase BOC52_21580 ENOG4107FQ9 ethanolamine ammonia-lyase BOC52_21590 ENOG4105C26 Dehydrogenase BOC52_21595 ENOG4108K3Z AraC family transcriptional regulator BOC52_21615 ENOG4105EJQ L-serine dehydratase BOC52_21635 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BOC52_21650 ENOG4105D9R oxidoreductase BOC52_21670 ENOG4105C4R Atp-dependent dna helicase BOC52_21675 ENOG4105MPD Cytochrome BOC52_21695 ENOG4108KU3 Integrase BOC52_21740 ENOG4108M1A Chitin-binding protein BOC52_21760 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_21765 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BOC52_21780 ENOG4106B0W Curli production assembly transport component CsgG BOC52_21790 ENOG4107Y60 (LipO)protein BOC52_21830 ENOG4105FUY alpha subunit BOC52_21840 ENOG4105CHR reductase BOC52_21855 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BOC52_21900 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BOC52_21910 ENOG4105DQF Hydrolase BOC52_21915 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BOC52_21930 ENOG4105E2K Glycosyl transferase (Group 1 BOC52_21940 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BOC52_21945 ENOG4107RD7 Flagellar Motor Protein, MotA BOC52_21950 ENOG4105ER2 Ompa motb domain protein BOC52_21955 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BOC52_21960 ENOG4105CBS Chea signal transduction histidine kinase BOC52_21965 ENOG4108V3W Chemotaxis protein, CheW BOC52_21970 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_21975 ENOG4105BZU Histidine kinase BOC52_21985 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BOC52_21995 ENOG4108VYJ response regulator receiver protein BOC52_22000 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BOC52_22020 ENOG4105D00 flagellar biosynthetic protein flhB BOC52_22025 ENOG4105D7B Flagellar biosynthesis protein flha BOC52_22030 ENOG4105FZW flagellar biosynthesis regulator FlhF BOC52_22030 ENOG4105FZW flagellar biosynthesis regulator FlhF BOC52_22040 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BOC52_22050 ENOG41086DT Membrane protein of unknown function BOC52_22055 ENOG4105SYT Methylenetetrahydrofolate reductase BOC52_22075 ENOG4105EA8 2-Nitropropane dioxygenase BOC52_22115 ENOG4108YXU transcriptional regulator AsnC family BOC52_22125 ENOG4105C5X domain protein BOC52_22130 ENOG4105K6T rare lipoprotein A BOC52_22145 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) BOC52_22150 ENOG4105W4M Transport-associated protein BOC52_22155 ENOG4105W2Z cytochrome C, class I BOC52_22165 ENOG4105C85 amino acid BOC52_22210 ENOG4106KE4 Dehydrogenase BOC52_22220 ENOG4105EQ0 Major Facilitator superfamily BOC52_22225 ENOG410811B TRANSCRIPTIONal BOC52_22235 ENOG4105EIF outer membrane protein W BOC52_22255 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BOC52_22270 ENOG4108V1U phospholipid-binding protein BOC52_22275 ENOG4107SW0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BOC52_22305 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BOC52_22310 ENOG4108XM1 transcriptional regulator AsnC family BOC52_22330 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BOC52_22335 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit BOC52_22340 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit BOC52_22345 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit BOC52_22350 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit BOC52_22400 ENOG4105CMM transposase BOC52_22430 ENOG4105PM1 preprotein translocase subunit SecE BOC52_22470 ENOG4105C9U ATP-dependent DNA helicase RecQ BOC52_22485 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BOC52_22490 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BOC52_22520 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BOC52_22555 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) BOC52_22590 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BOC52_22605 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BOC52_22650 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) BOC52_22655 ENOG4105D52 delta-aminolevulinic acid dehydratase BOC52_22660 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BOC52_22665 ENOG4106RE7 Cytochrome BOC52_22670 ENOG4105EBH Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity) BOC52_22675 ENOG4105CRE cytochrome C BOC52_22680 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) BOC52_22685 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) BOC52_22695 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BOC52_22710 ENOG4108JQC penicillin-binding protein 1A BOC52_22730 ENOG4105E4G Type IV pilus BOC52_22735 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BOC52_22745 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein BOC52_22755 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component BOC52_22760 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BOC52_22765 ENOG4108IJ9 (ABC) transporter BOC52_22770 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BOC52_22820 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BOC52_22830 ENOG4105DHJ ABC, transporter BOC52_22835 ENOG4105CY3 ABC transporter, permease BOC52_22840 ENOG4107PE3 Mammalian cell entry related domain protein BOC52_22865 ENOG4105DA5 (ABC) transporter BOC52_22870 ENOG4105E3A (ABC) transporter BOC52_22895 ENOG4105CIH Imidazole acetol-phosphate transaminase BOC52_22905 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BOC52_22910 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BOC52_22940 ENOG4105K59 histidine triad (HIT) protein BOC52_22955 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BOC52_22960 ENOG4105C0H protease BOC52_22965 ENOG4107QNR UPF0135 protein BOC52_22970 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BOC52_22975 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BOC52_22980 ENOG4105EIX cytochrome c1 BOC52_22985 ENOG4107MKT Stringent starvation protein a BOC52_22990 ENOG4105KB2 stringent starvation protein b BOC52_23085 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_23095 ENOG4105UYK outer membrane protein a BOC52_23135 ENOG4108JJA ABC, transporter BOC52_23140 ENOG4108MBX Secretion Protein BOC52_23175 ENOG4105CD8 aminopeptidase N BOC52_23250 ENOG4105R8A Heat shock protein BOC52_23260 ENOG4105VEQ Cold shock protein BOC52_23265 ENOG4107QTZ amino acid BOC52_23270 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BOC52_23275 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BOC52_23285 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BOC52_23315 ENOG4105DC7 peptidase M24 BOC52_23320 ENOG4105D3W isochorismatase BOC52_23330 ENOG4105C5H ABC transporter BOC52_23345 ENOG4106IDA glycerophosphoryl diester phosphodiesterase BOC52_23385 ENOG4105C3G gtp-binding protein BOC52_23440 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BOC52_23445 ENOG4105T95 Thiol disulfide interChange protein BOC52_23455 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BOC52_23460 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BOC52_23480 ENOG4105DDQ anthranilate synthase BOC52_23495 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BOC52_23510 ENOG4105NWN ApaG protein BOC52_23515 ENOG4105CA3 membrane-bound lytic murein transglycosylase BOC52_23525 ENOG4108ZJI phenylacetic acid degradation protein BOC52_23530 ENOG4108UKI Enoyl-CoA hydratase BOC52_23535 ENOG4105CHU acetyl-coa acetyltransferase BOC52_23545 ENOG4105E39 Enoyl-CoA hydratase BOC52_23585 ENOG4108J2R molybdopterin oxidoreductase BOC52_23590 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_23595 ENOG4108Z9W Outer membrane porin BOC52_23615 ENOG4105N8N Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BOC52_23620 ENOG4105CJN penicillin-binding protein BOC52_23625 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BOC52_23630 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BOC52_23665 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BOC52_23670 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BOC52_23675 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BOC52_23710 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BOC52_23720 ENOG4105M6F mutator MutT protein BOC52_23725 ENOG41067SF Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) BOC52_23735 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BOC52_23740 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) BOC52_23750 ENOG4107QHF type ii secretion system protein e BOC52_23755 ENOG4108JU6 CBS domain protein BOC52_23765 ENOG4105EAH synthase BOC52_23810 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BOC52_23815 ENOG4108UGV hypoxanthine phosphoribosyltransferase BOC52_23820 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BOC52_23845 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BOC52_23855 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BOC52_23880 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BOC52_23895 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BOC52_23900 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BOC52_23905 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BOC52_23910 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BOC52_23920 ENOG4105DFU Cell wall formation (By similarity) BOC52_23925 ENOG4105IPS esterase BOC52_23935 ENOG4105E2X shikimate dehydrogenase BOC52_23940 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase BOC52_23960 ENOG4105J4Q Transcriptional regulator BOC52_23965 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 BOC52_23975 ENOG4105CHR reductase BOC52_23990 ENOG4105CNN ABC, transporter BOC52_23995 ENOG4105FGE Short-chain dehydrogenase reductase Sdr BOC52_24005 ENOG4105SKN orotidine 5''-phosphate decarboxylase BOC52_24010 ENOG4107TH8 cina domain protein BOC52_24015 ENOG4108ZAI phosphatidylglycerophosphatase a BOC52_24020 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BOC52_24025 ENOG4105C6K Malic enzyme BOC52_24045 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BOC52_24055 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BOC52_24060 ENOG4105CV1 Transketolase (EC 2.2.1.1) BOC52_24065 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BOC52_24075 ENOG4105EQ0 Major Facilitator superfamily BOC52_24085 ENOG4107B2H carbonic anhydrase BOC52_24090 ENOG4105DND Transcriptional regulator BOC52_24105 ENOG4105CK2 sodium dicarboxylate symporter BOC52_24110 ENOG4105DHG Allantoate amidinohydrolase BOC52_24120 ENOG41090R7 Ferric uptake BOC52_24125 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BOC52_24155 ENOG4105DJF DNA polymerase III, delta' subunit BOC52_24160 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) BOC52_24165 ENOG4108YXA Membrane BOC52_24175 ENOG4105CHC glucokinase (EC 2.7.1.2) BOC52_24185 ENOG4105C01 Dihydroxy-acid dehydratase BOC52_24190 ENOG4108UHU Aldolase BOC52_24195 ENOG4105C6Z Gluconate BOC52_24205 ENOG4107QTF adenylosuccinate lyase BOC52_24215 ENOG4107YNJ LysR family Transcriptional regulator BOC52_24225 ENOG4105D82 Glutamate dehydrogenase BOC52_24230 ENOG4107RP9 extracellular solute-binding protein, family 3 BOC52_24235 ENOG4105EAD ABC transporter BOC52_24240 ENOG4105DRP amino acid AbC transporter BOC52_24245 ENOG4105CDA abc transporter atp-binding protein BOC52_24290 ENOG4105E7A Glutamine amidotransferase BOC52_24300 ENOG4105EKE dihydroorotase BOC52_24335 ENOG4105E7U AraC family transcriptional regulator BOC52_24340 ENOG4105CYM Glutathione S-transferase BOC52_24345 ENOG4105CYM Glutathione S-transferase BOC52_24360 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BOC52_24370 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BOC52_24410 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BOC52_24415 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BOC52_24420 ENOG4105D0A hydroxylase BOC52_24425 ENOG4107RAQ aminopeptidase BOC52_24435 ENOG4108U78 Glutathione S-transferase BOC52_24440 ENOG4105CBC glutamate synthase BOC52_24455 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BOC52_24460 ENOG4105W8H transhydrogenase (subunit alpha BOC52_24465 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BOC52_24510 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BOC52_24525 ENOG4105DY2 Paraquat-inducible protein b BOC52_24530 ENOG4105F1S paraquat-inducible protein a BOC52_24550 ENOG4108YYC ycei family BOC52_24555 ENOG4108YYC ycei family BOC52_24570 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BOC52_24575 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BOC52_24580 ENOG4105VIE preprotein translocase, subunit YajC BOC52_24590 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BOC52_24600 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BOC52_24605 ENOG4105CB5 ATP-dependent DNA helicase recG BOC52_24610 ENOG4105C5Q Transcriptional regulator BOC52_24635 ENOG4107YPT transcriptional regulator BOC52_24650 ENOG4108TXN phosphonate metabolism protein BOC52_24685 ENOG4105ENV phosphonate C-P lyase system protein PhnK BOC52_24690 ENOG4105HRV phosphonate c-p lyase system protein phnl BOC52_24695 ENOG4105FD8 phosphonate metabolism protein PhnM BOC52_24700 ENOG4105D5T phosphonate abc transporter BOC52_24705 ENOG4105EHI Phosphonate ABC transporter, periplasmic BOC52_24725 ENOG4105II7 pyrroline-5-carboxylate reductase BOC52_24730 ENOG4105DFA alanine racemase domain protein BOC52_24735 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BOC52_24740 ENOG4105EU8 FAD linked oxidase domain protein BOC52_24745 ENOG4105CQB FAD linked oxidase domain protein BOC52_24750 ENOG4105CQB FAD linked oxidase domain protein BOC52_24755 ENOG4108WBT adenosyltransferase BOC52_24760 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BOC52_24770 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BOC52_24780 ENOG4105D1U peptidase U62 modulator of DNA gyrase BOC52_24790 ENOG4105QD6 exported protein BOC52_24795 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) BOC52_24800 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BOC52_24805 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BOC52_24820 ENOG4105VEJ Heat shock protein BOC52_24845 ENOG4105CRQ synthase (Component I) BOC52_24860 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BOC52_24865 ENOG4105DJ0 Poly(A) Polymerase BOC52_24875 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) BOC52_24900 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BOC52_24905 ENOG4105DQR SNARE associated Golgi BOC52_24910 ENOG4105D64 Mechanosensitive ion channel BOC52_24940 ENOG4107V52 polysaccharide export BOC52_24945 ENOG4105ECX polysaccharide export BOC52_24990 ENOG4108DMA Nad-dependent epimerase dehydratase BOC52_25000 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) BOC52_25010 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BOC52_25015 ENOG41084CK capsule polysaccharide BOC52_25025 ENOG4107T7U Sulfatase BOC52_25035 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BOC52_25040 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BOC52_25080 ENOG4107S4Z Activates expression of the rhaBAD and rhaT operons (By similarity) BOC52_25085 ENOG4105D3Q Sugar transferase BOC52_25115 ENOG4105D7W serine acetyltransferase BOC52_25130 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BOC52_25135 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BOC52_25140 ENOG4105C2X Arabinose 5-phosphate isomerase BOC52_25170 ENOG4105KCK Peptidoglycan-associated lipoprotein BOC52_25185 ENOG4105M8F Biopolymer transport protein exbD tolR BOC52_25190 ENOG4105E02 MotA TolQ exbB proton channel BOC52_25195 ENOG4107YD3 Thioesterase BOC52_25200 ENOG4105EMU Dehydrogenase BOC52_25210 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BOC52_25260 ENOG4105D3R alkyl hydroperoxide reductase BOC52_25270 ENOG4105C1G acyl-Coa dehydrogenase BOC52_25300 ENOG4105E2Q 3-(3-hydroxy-phenyl)propionate hydroxylase BOC52_25310 ENOG4105D2S major facilitator superfamily BOC52_25340 ENOG4105F27 Major Facilitator BOC52_25345 ENOG4105E7Q Cob(II)yrinic acid a,c-diamide reductase BOC52_25355 ENOG4105CBN LysR family transcriptional regulator BOC52_25365 ENOG4105C5R Aminotransferase BOC52_25375 ENOG4105DWP Membrane BOC52_25400 ENOG4105C7W Xanthine dehydrogenase BOC52_25415 ENOG4105E0K tonB-dependent siderophore receptor BOC52_25420 ENOG4105E0A ABC, transporter BOC52_25430 ENOG4105EHG Permease protein BOC52_25470 ENOG4107TSN permease BOC52_25485 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BOC52_25490 ENOG4105E82 cytochrome subunit of dehydrogenase BOC52_25550 ENOG4105CB2 alcohol dehydrogenase BOC52_25555 ENOG4105KVH Transcriptional regulator BOC52_25590 ENOG4105VCQ rubredoxin BOC52_25600 ENOG4108UJU UPF0301 protein BOC52_25610 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BOC52_25620 ENOG4105CD3 dihydroorotase BOC52_25645 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BOC52_25685 ENOG4105K64 Glycosyl transferase, family 2 BOC52_25700 ENOG4105ESV Glycosyl transferase, family 4 BOC52_25715 ENOG4105CMR udp-glucose 4-epimerase BOC52_25745 ENOG4105D16 lipopolysaccharide heptosyltransferase i BOC52_25755 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BOC52_25795 ENOG4108IV0 ABC, transporter BOC52_25800 ENOG4105C2J ABC transporter BOC52_25810 ENOG4105C32 Amino acid ABC transporter (Permease) BOC52_25815 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein BOC52_25825 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BOC52_25835 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) BOC52_25845 ENOG4105D4P Coproporphyrinogen iii oxidase BOC52_25855 ENOG4105KRS Proteinase inhibitor BOC52_25905 ENOG4105BZU Histidine kinase BOC52_25940 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BOC52_25945 ENOG4105DMQ Methyltransferase BOC52_25970 ENOG4108VIA integral membrane protein BOC52_26030 ENOG4105CHM Aminotransferase BOC52_26045 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BOC52_26060 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BOC52_26085 ENOG4105C2C drug resistance transporter, Bcr CflA BOC52_26100 ENOG4105CDA abc transporter atp-binding protein BOC52_26105 ENOG4105E5Q amino acid AbC transporter BOC52_26110 ENOG4105EAB amino acid AbC transporter BOC52_26125 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) BOC52_26130 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BOC52_26140 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BOC52_26150 ENOG4108IJ9 (ABC) transporter BOC52_26155 ENOG4105EN6 Membrane BOC52_26160 ENOG4105C98 muts2 protein BOC52_26165 ENOG4105C3M thioredoxin reductase BOC52_26175 ENOG4105CNU cell division protein FtsK BOC52_26180 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) BOC52_26190 ENOG4105D1H recombination factor protein RarA BOC52_26315 ENOG4105CS6 Rhs element vgr protein BOC52_26360 ENOG4108YXQ IS66 Orf2 family protein BOC52_26365 ENOG4105E5H Transposase BOC52_26370 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein BOC52_26385 ENOG4105DFP Integrase BOC52_26420 ENOG4107QMS site-determining protein BOC52_26435 ENOG4105CMQ Chloride channel BOC52_26440 ENOG4105D16 lipopolysaccharide heptosyltransferase i BOC52_26450 ENOG4105CSH Transporter BOC52_26485 ENOG4105CSA Coproporphyrinogen iii oxidase BOC52_26490 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BOC52_26500 ENOG4105DSJ YicC domain protein BOC52_26505 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BOC52_26515 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BOC52_26530 ENOG4108RRZ Transcription elongation factor GreB BOC52_26540 ENOG4108Z9W Outer membrane porin BOC52_26550 ENOG4105VEQ Cold shock protein BOC52_26555 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BOC52_26635 ENOG4105DZ2 Transcriptional regulator BOC52_26645 ENOG4105CD8 aminopeptidase N BOC52_26670 ENOG4107QUY Guanine deaminase BOC52_26675 ENOG4105C7N Xanthine uracil vitamin C permease BOC52_26680 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) BOC52_26695 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) BOC52_26700 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BOC52_26705 ENOG4108Z86 Glutamine amidotransferase BOC52_26710 ENOG4105CSH Transporter BOC52_26740 ENOG4108JB9 formate dehydrogenase BOC52_26745 ENOG4107QIZ NADH dehydrogenase BOC52_26755 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BOC52_26765 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BOC52_26775 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BOC52_26780 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BOC52_26785 ENOG4105UYK outer membrane protein a BOC52_26795 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BOC52_26805 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BOC52_26820 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BOC52_26830 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BOC52_26845 ENOG4105CFV Tetratricopeptide repeat protein BOC52_26850 ENOG4105C6Y Udp-glucose 6-dehydrogenase BOC52_26855 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) BOC52_26875 ENOG4105C6T cysteine synthase BOC52_26880 ENOG4105CVE Lytic murein transglycosylase BOC52_26895 ENOG4105E5G Alpha beta hydrolase fold BOC52_26900 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BOC52_26905 ENOG4108UMI ABC transporter, permease BOC52_26910 ENOG4105D01 (LipO)protein BOC52_26915 ENOG4105BZJ Electron transfer flavoprotein BOC52_26920 ENOG4105C10 Electron transfer flavoprotein BOC52_26925 ENOG4105CSU acyl-Coa dehydrogenase BOC52_26935 ENOG4105EW9 transcriptional regulator AsnC family BOC52_26950 ENOG4105DKB L-sorbosone dehydrogenase BOC52_26995 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) BOC52_27010 ENOG4105D0M Protease HtpX homolog BOC52_27020 ENOG4108RIR Molybdenum cofactor biosynthesis protein BOC52_27025 ENOG4105N42 UPF0307 protein BOC52_27035 ENOG4105CMS peptidase U62, modulator of DNA gyrase BOC52_27045 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BOC52_27050 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_27080 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BOC52_27090 ENOG4108ZHR arsR family transcriptional regulator BOC52_27105 ENOG4105NAU thioesterase Superfamily protein BOC52_27125 ENOG4107QI1 Mate efflux family protein BOC52_27130 ENOG4105WQ3 Rna-binding protein BOC52_27155 ENOG4108RH0 Crea protein BOC52_27170 ENOG4108Z4U Ferredoxin BOC52_27180 ENOG4107RH7 Nicotinate phosphoribosyltransferase BOC52_27195 ENOG4105C5I Dehydrogenase BOC52_27200 ENOG4107QSV RmuC domain protein BOC52_27215 ENOG4105CVM Molybdenum cofactor synthesis domain protein BOC52_27225 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BOC52_27230 ENOG4105C03 ribonuclease BOC52_27240 ENOG4105EI2 Pseudouridine synthase BOC52_27245 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BOC52_27260 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BOC52_27265 ENOG4108UHJ MAF-like protein BOC52_27270 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BOC52_27290 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BOC52_27295 ENOG4105CHR reductase BOC52_27305 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BOC52_27315 ENOG4105EMN RNA polymerase sigma factor BOC52_27325 ENOG4105VQK sigma E regulatory protein, MucB RseB BOC52_27345 ENOG4105C3F Signal peptidase i BOC52_27350 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BOC52_27355 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BOC52_27375 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) BOC52_27380 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_27400 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BOC52_27420 ENOG4108ZGC gaf domain protein BOC52_27425 ENOG4105CC0 LysR family Transcriptional regulator BOC52_27430 ENOG4105EUB pirin domain protein BOC52_27435 ENOG4107YB6 acetyltransferase, (GNAT) family BOC52_27450 ENOG4108ZX6 Electron transport protein SCO1 SenC BOC52_27460 ENOG4108K4C ec 3.1.3.12 BOC52_27465 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase BOC52_27470 ENOG4105BZ1 (ABC) transporter BOC52_27490 ENOG4105MWK D-amino acid dehydrogenase, small subunit BOC52_27495 ENOG4105CP9 extracellular ligand-binding receptor BOC52_27525 ENOG4105CPT Alpha beta hydrolase BOC52_27535 ENOG4105DEN Luciferase family BOC52_27550 ENOG410901P UPF0249 protein BOC52_27565 ENOG4105DSP amino acid AbC transporter BOC52_27570 ENOG4106YG3 ABC transporter BOC52_27575 ENOG4108JEH abc transporter atp-binding protein BOC52_27580 ENOG4105ECQ AraC Family Transcriptional Regulator BOC52_27595 ENOG4105C8Y Acetylornithine aminotransferase BOC52_27600 ENOG4108T2Z Arginine BOC52_27635 ENOG4105E89 ABC transporter BOC52_27645 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BOC52_27650 ENOG4105CCU oxidase (Subunit III) BOC52_27690 ENOG4105VG1 fes assembly suf system protein BOC52_27695 ENOG4108UNV SUF system FeS assembly protein, NifU family BOC52_27700 ENOG4105C9B Cysteine desulfurase BOC52_27710 ENOG4105C3K feS assembly ATPase SufC BOC52_27735 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_27740 ENOG4105D4P Coproporphyrinogen iii oxidase BOC52_27745 ENOG4105EYW Ion transport protein BOC52_27750 ENOG4105FQT BOC52_27760 ENOG4105CFP Peptidase U32 BOC52_27765 ENOG4106RZ4 Peptidase U32 BOC52_27770 ENOG4105XPQ lipid carrier protein BOC52_27810 ENOG4105VG1 fes assembly suf system protein BOC52_27815 ENOG4105DSQ Nitric oxide reductase BOC52_27830 ENOG4105CVP deoxyribo-dipyrimidine photolyase BOC52_27835 ENOG4108EJ0 Catalyzes the synthesis of activated sulfate (By similarity) BOC52_27880 ENOG4105CGP Urocanate hydratase BOC52_27895 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BOC52_27930 ENOG4108Z86 Glutamine amidotransferase BOC52_27935 ENOG4105CFQ glutamine synthetase BOC52_27940 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BOC52_27985 ENOG4107RSM transcriptional regulator BOC52_27990 ENOG4105CSU acyl-Coa dehydrogenase BOC52_28005 ENOG4105CSH Transporter BOC52_28015 ENOG4108EKC n-acetylglutamate synthase BOC52_28020 ENOG4105CQ7 ATP-dependent helicase BOC52_28045 ENOG4107TH8 cina domain protein BOC52_28060 ENOG4105C5F glutamine synthetase BOC52_28065 ENOG4105CUX Signal transduction histidine kinase BOC52_28070 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_28080 ENOG4105WH1 Two component transcriptional regulator luxr family BOC52_28085 ENOG4105BZU Histidine kinase BOC52_28090 ENOG4105D0D Nitrate reductase 2, gamma subunit BOC52_28095 ENOG4108NZN Respiratory nitrate reductase 2 delta chain BOC52_28100 ENOG4108IUE nitrate reductase beta subunit BOC52_28105 ENOG4105CRU nitrate reductase, alpha subunit BOC52_28110 ENOG4105DQQ Major facilitator superfamily MFS_1 BOC52_28130 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BOC52_28135 ENOG4105DGW oligopeptidase A BOC52_28150 ENOG4108ZXC Two component transcriptional regulator, luxr family BOC52_28155 ENOG4105BZU Histidine kinase BOC52_28165 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BOC52_28170 ENOG4107QSN dihydrolipoamide acetyltransferase BOC52_28175 ENOG4107QN2 dihydrolipoyl dehydrogenase BOC52_28185 ENOG4108WFY phasin family BOC52_28195 ENOG41061WM D-Alanyl-D-Alanine BOC52_28205 ENOG41069M3 Transcriptional regulator BOC52_28220 ENOG4107QR9 Iron-sulfur cluster binding protein BOC52_28230 ENOG4105KJF protein tyrosine phosphatase BOC52_28235 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family BOC52_28240 ENOG4105C3J Cysteine desulfurase BOC52_28245 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BOC52_28255 ENOG4108SWN Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity) BOC52_28265 ENOG4108ZIT Ferredoxin, 2FE-2S BOC52_28270 ENOG4105WVQ Fe-S assembly protein IscX BOC52_28295 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BOC52_28300 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BOC52_28305 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BOC52_28325 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BOC52_28330 ENOG4105EYA deoxyribonuclease BOC52_28335 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BOC52_28340 ENOG4108MUZ hydrolase BOC52_28365 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BOC52_28375 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BOC52_28380 ENOG4108Z0R Transferase BOC52_28385 ENOG4105ED9 Protein of unknown function (DUF455) BOC52_28395 ENOG4105D74 hydrolase BOC52_28405 ENOG4105DB7 PHP domain protein BOC52_28410 ENOG4107RTD sua5 ycio yrdc ywlc family protein BOC52_28415 ENOG4108Z4T Peptidase M50 BOC52_28420 ENOG4105C31 Tryptophanyl-tRNA synthetase BOC52_28430 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BOC52_28435 ENOG4105GJM (LipO)protein BOC52_28440 ENOG4105CY0 Metallo-Beta-Lactamase BOC52_28450 ENOG4105EZE Cupin 4 family protein BOC52_28455 ENOG4108YZY peptidylprolyl cis-trans isomerase BOC52_28490 ENOG4105ECY inositol monophosphatase BOC52_28505 ENOG4105D7W serine acetyltransferase BOC52_28515 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) BOC52_28525 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BOC52_28550 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BOC52_28560 ENOG4105CFH Aspartokinase BOC52_28615 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) BOC52_28665 ENOG4105CV1 Transketolase (EC 2.2.1.1) BOC52_28670 ENOG4108IUS Transketolase BOC52_28680 ENOG4105EXC Acyl-transferase BOC52_28685 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BOC52_28705 ENOG410880H cysteine synthase BOC52_28725 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BOC52_28740 ENOG4108Z4U Ferredoxin BOC52_28745 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BOC52_28750 ENOG4105DP0 ferredoxin-NADP reductase BOC52_28760 ENOG4108J2R molybdopterin oxidoreductase BOC52_28780 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BOC52_28790 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BOC52_28795 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BOC52_28800 ENOG4108JQ5 ABC transporter BOC52_28805 ENOG4105K4H Nlp p60 protein BOC52_28810 ENOG4105D78 K07001 NTE family protein BOC52_28855 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) BOC52_28875 ENOG4107QP3 malate synthase g BOC52_28885 ENOG4105EJC lysr family transcriptional regulator BOC52_28890 ENOG41068KF Universal stress protein BOC52_28900 ENOG4105C1J atp-dependent rna helicase BOC52_28910 ENOG41072GX Peptidase M22 Glycoprotease BOC52_28920 ENOG4108UN4 phage SPO1 DNA polymerase-related protein BOC52_28935 ENOG4105DWF phosphomethylpyrimidine kinase BOC52_28940 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) BOC52_28950 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BOC52_28960 ENOG4105C5H ABC transporter BOC52_28980 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BOC52_28990 ENOG4105KUZ arsenate reductase BOC52_29035 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BOC52_29040 ENOG4105FE9 pseudouridine synthase BOC52_29050 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BOC52_29075 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BOC52_29080 ENOG4105KNE Phosphatidate cytidylyltransferase BOC52_29090 ENOG4105DZP Membrane-associated zinc metalloprotease BOC52_29095 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BOC52_29120 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BOC52_29170 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BOC52_29180 ENOG4107QX8 SPFH domain, Band 7 family protein BOC52_29190 ENOG4108Z1B Cyclase dehydrase BOC52_29200 ENOG4105DXC membrane BOC52_29225 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BOC52_29305 ENOG4105VTS DnaJ-like, subfamily C BOC52_29310 ENOG4108Z6B deaminase BOC52_29315 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BOC52_29325 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BOC52_29340 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) BOC52_29345 ENOG4105DHG Allantoate amidinohydrolase BOC52_29370 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BOC52_29385 ENOG4105WKW Pfam:DUF1458 BOC52_29420 ENOG4108JQC penicillin-binding protein 1A BOC52_29450 ENOG4105CWC Acetylornithine deacetylase BOC52_29465 ENOG4108JA2 transcriptioN-repair coupling factor BOC52_29480 ENOG4108X7C Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BOC52_29490 ENOG4105E0F Histidine kinase BOC52_29495 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BOC52_29520 ENOG4105FE1 phytoene synthase BOC52_29600 ENOG4105DGU Histone deacetylase BOC52_29635 ENOG4105NTK Transcriptional repressor Mpra BOC52_29640 ENOG4105BZW Glycerate kinase BOC52_29660 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BOC52_29730 ENOG4108UJV acyl-CoA thioesterase i BOC52_29735 ENOG4108I0Y (ABC) transporter BOC52_29745 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BOC52_29750 ENOG4105MWK D-amino acid dehydrogenase, small subunit BOC52_29760 ENOG4108ETH Formylglycinamide ribotide synthetase BOC52_29770 ENOG4107TF3 peptidylprolyl cis-trans isomerase BOC52_29795 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_29800 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BOC52_29805 ENOG4108RWI nicotinamidase BOC52_29810 ENOG4105CHU acetyl-coa acetyltransferase BOC52_29840 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BOC52_29860 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) BOC52_29865 ENOG4105HHA aminodeoxychorismate lyase BOC52_29875 ENOG4107QRG dna polymerase iii BOC52_29880 ENOG4107TCE N-acetyltransferase BOC52_29885 ENOG4105F8V Hydrolase, tatD family BOC52_29905 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BOC52_29915 ENOG4105CPK Glycosyl transferase (Group 1 BOC52_29945 ENOG4105HDK L-asparaginase BOC52_29955 ENOG4109066 lysm domain bon superfamily protein BOC52_29965 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BOC52_29970 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BOC52_29975 ENOG41060W2 glyoxylate carboligase BOC52_29980 ENOG4105EJC lysr family transcriptional regulator BOC52_29995 ENOG4105EMN RNA polymerase sigma factor BOC52_30030 ENOG4105CDU Replicative dna helicase BOC52_30040 ENOG4107QXV Phosphate transporter BOC52_30050 ENOG4105K4H Nlp p60 protein BOC52_30055 ENOG4108IAB Phoh family BOC52_30065 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BOC52_30070 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BOC52_30075 ENOG4105C3I Nad-dependent epimerase dehydratase BOC52_30085 ENOG4105CKK Glycosyl transferase, family 2 BOC52_30090 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BOC52_30100 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BOC52_30110 ENOG4105CHM Aminotransferase BOC52_30115 ENOG4105D6E homoserine dehydrogenase BOC52_30135 ENOG4105CVM Molybdenum cofactor synthesis domain protein BOC52_30140 ENOG4105M00 molybdopterin converting factor, subunit 1 BOC52_30145 ENOG4108ZAF Molybdopterin BOC52_30150 ENOG4105VIG Sec-independent protein translocase protein TatC BOC52_30160 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_30185 ENOG4107QI1 Mate efflux family protein BOC52_30210 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_30215 ENOG4108Z6Z Transcriptional regulator BOC52_30220 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BOC52_30230 ENOG4105K63 Thioredoxin BOC52_30240 ENOG4107QMP dna polymerase iii subunits gamma and tau BOC52_30245 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BOC52_30255 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BOC52_30270 ENOG4108K5P (LipO)protein BOC52_30275 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BOC52_30295 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BOC52_30300 ENOG4108MN8 Membrane BOC52_30320 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BOC52_30335 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BOC52_30350 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BOC52_30355 ENOG4107QJR hflk protein BOC52_30360 ENOG4105EPW hflc protein BOC52_30380 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) BOC52_30405 ENOG4105BZM domain protein BOC52_30420 ENOG4105DVT helicase BOC52_30430 ENOG4105C34 Pseudouridine synthase BOC52_30435 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BOC52_30440 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class BOC52_30445 ENOG4105CHU acetyl-coa acetyltransferase BOC52_30450 ENOG4105CHR reductase BOC52_30475 ENOG4105CHU acetyl-coa acetyltransferase BOC52_30485 ENOG4105C28 cystathionine BOC52_30490 ENOG4105EAC phosphoserine phosphatase BOC52_30510 ENOG4108JJB ABC transporter BOC52_30515 ENOG41066T0 asmA family BOC52_30525 ENOG4105C5H ABC transporter BOC52_30570 ENOG4107RUE extracellular solute-binding protein family 1 BOC52_30575 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BOC52_30580 ENOG4105F38 ABC transporter, permease BOC52_30585 ENOG4105D38 putrescine abc transporter BOC52_30615 ENOG4105VMP Transcriptional regulator BOC52_30635 ENOG4107TXC Transcriptional regulator BOC52_30650 ENOG4105BZS acriflavin resistance protein BOC52_30660 ENOG4108IG5 Transcriptional regulator BOC52_30670 ENOG4105HMI Membrane BOC52_30675 ENOG4105DUM transcriptional regulator, lysR family BOC52_30690 ENOG4105D7K pfkb domain protein BOC52_30700 ENOG4105C5I Dehydrogenase BOC52_30710 ENOG4105ETE Transcriptional regulator (LacI family BOC52_30795 ENOG4105D7N magnesium and cobalt transport protein CorA BOC52_30825 ENOG4105EGS Mechanosensitive ion channel BOC52_30835 ENOG4105HEE Binding Domain protein BOC52_30860 ENOG4108T0W nitrous oxide maturation protein NosY BOC52_30865 ENOG4105CIG ABC transporter BOC52_30885 ENOG41081YB ApbE family BOC52_30910 ENOG4105CMT Dihydroxyacetone kinase BOC52_31010 ENOG4108VCD Chaperone BOC52_31015 ENOG4105CW0 outer membrane usher protein BOC52_31070 ENOG41068CG regulatoR BOC52_31075 ENOG4105BZU Histidine kinase BOC52_31115 ENOG4105J1P transposase, IS3 IS911 family protein BOC52_31130 ENOG4107M1U Histone family protein nucleoid-structuring protein H-NS BOC52_31175 ENOG4105RQ9 TPR repeat-containing protein BOC52_31180 ENOG4107T1U Catalyzes the synthesis of activated sulfate (By similarity) BOC52_31185 ENOG4108RQS Two component transcriptional regulator (Winged helix family BOC52_31220 ENOG4105NCT RNA Polymerase BOC52_31225 ENOG4108ZJD Protein of unknown function (DUF1109) BOC52_31245 ENOG4105E18 UPF0276 protein BOC52_31290 ENOG410880H cysteine synthase BOC52_31310 ENOG4105CH7 arginosuccinase BOC52_31325 ENOG4105X1Z Methyltransferase type 12 BOC52_31330 ENOG4105CIH Imidazole acetol-phosphate transaminase BOC52_31355 ENOG41085A6 mbth domain-containing protein BOC52_31375 ENOG4108Z9W Outer membrane porin BOC52_31385 ENOG4108K01 transcriptional regulator BOC52_31390 ENOG4108PCN EamA-like transporter family BOC52_31395 ENOG4108V3W Chemotaxis protein, CheW BOC52_31400 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_31415 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_31420 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_31430 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BOC52_31435 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BOC52_31440 ENOG4108IJ8 ABC transporter BOC52_31445 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BOC52_31460 ENOG4105D5Q Arginine ornithine antiporter BOC52_31465 ENOG4105CEU Arginine dihydrolase BOC52_31470 ENOG4105DBV ornithine carbamoyltransferase BOC52_31475 ENOG4105C5B carbamate kinase BOC52_31495 ENOG410642W LysR family Transcriptional regulator BOC52_31500 ENOG4105CYM Glutathione S-transferase BOC52_31515 ENOG4105CP9 extracellular ligand-binding receptor BOC52_31520 ENOG4108ZT1 Transcriptional regulator BOC52_31525 ENOG4105DJ2 Major Facilitator Superfamily BOC52_31530 ENOG4105F32 YngK protein BOC52_31535 ENOG4105CIA precorrin-4 C(11)-methyltransferase BOC52_31550 ENOG4105EE8 May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity) BOC52_31555 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase BOC52_31560 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BOC52_31565 ENOG41081F0 Precorrin-8x methylmutase BOC52_31570 ENOG4105DVK Precorrin-2 c20-methyltransferase BOC52_31580 ENOG4108NNZ chitinase BOC52_31600 ENOG4106CJB Phospholipase Carboxylesterase BOC52_31625 ENOG4105CTK cobaltochelatase, cobn subunit BOC52_31630 ENOG4107QRP cobalamin biosynthesis protein CobW BOC52_31645 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BOC52_31650 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BOC52_31660 ENOG4108V3E phosphoribosylglycinamide formyltransferase BOC52_31665 ENOG4105E0K tonB-dependent siderophore receptor BOC52_31690 ENOG4105IBP Cyclic peptide transporter BOC52_31705 ENOG4105J76 Periplasmic binding protein BOC52_31715 ENOG4105S6R Iron-hydroxamate transporter permease subunit BOC52_31720 ENOG4105E0A ABC, transporter BOC52_31750 ENOG4105CHR reductase BOC52_31755 ENOG4105CMG Carbohydrate kinase BOC52_31770 ENOG4105CNN ABC, transporter BOC52_31780 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BOC52_31805 ENOG4105BZ1 (ABC) transporter BOC52_31815 ENOG4108FZ9 Chaperone BOC52_31820 ENOG4106PG1 outer membrane usher protein BOC52_31825 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon BOC52_31855 ENOG4105BZS acriflavin resistance protein BOC52_31865 ENOG4108IG5 Transcriptional regulator BOC52_31870 ENOG4105DR5 peptidase BOC52_31875 ENOG4105E5Q amino acid AbC transporter BOC52_31880 ENOG4105EZ7 amino acid ABC transporter BOC52_31895 ENOG4105EAB amino acid AbC transporter BOC52_31960 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BOC52_31980 ENOG4105CSH Transporter BOC52_31990 ENOG4105ED1 spovr family BOC52_32000 ENOG4105CYN Serine protein kinase BOC52_32015 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_32020 ENOG4108RVA ribokinase BOC52_32025 ENOG4105ETE Transcriptional regulator (LacI family BOC52_32030 ENOG4105CNN ABC, transporter BOC52_32035 ENOG4105C2J ABC transporter BOC52_32040 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BOC52_32045 ENOG4107R11 Transcriptional regulator BOC52_32050 ENOG4108IJ6 ABC transporter BOC52_32060 ENOG4108I5D sulfate abc transporter BOC52_32065 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BOC52_32100 ENOG4105CJ1 ABC, transporter BOC52_32120 ENOG4107S21 permease BOC52_32125 ENOG4105CPC Aldo Keto reductase BOC52_32135 ENOG4107YPT transcriptional regulator BOC52_32155 ENOG4105CK2 sodium dicarboxylate symporter BOC52_32165 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BOC52_32195 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BOC52_32220 ENOG41090KN UPF0303 protein BOC52_32235 ENOG4105E09 nadh pyrophosphatase BOC52_32255 ENOG4105EAB amino acid AbC transporter BOC52_32260 ENOG4105E5Q amino acid AbC transporter BOC52_32265 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BOC52_32270 ENOG4108PVQ transcriptional regulator BOC52_32280 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BOC52_32290 ENOG4105C2N RNA methyltransferase TrmH family group 3 BOC52_32295 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BOC52_32310 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_32340 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BOC52_32345 ENOG4105JHE Major Facilitator Superfamily BOC52_32355 ENOG4105CEY Amp-dependent synthetase and ligase BOC52_32380 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BOC52_32485 ENOG4105D6Z AFG1 family ATPase BOC52_32490 ENOG4107QN2 dihydrolipoyl dehydrogenase BOC52_32495 ENOG4105C7S Dehydrogenase BOC52_32500 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BOC52_32515 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BOC52_32520 ENOG4105ETP RND efflux system, outer membrane lipoprotein BOC52_32525 ENOG4105CW7 secretion protein, HlyD family BOC52_32530 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_32540 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BOC52_32555 ENOG4105CHV Transcription elongation factor NusA BOC52_32565 ENOG4105FE9 pseudouridine synthase BOC52_32575 ENOG4108M0I Transcriptional regulator BOC52_32620 ENOG4105GJM (LipO)protein BOC52_32665 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BOC52_32690 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BOC52_32705 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BOC52_32710 ENOG4105M4H endoribonuclease L-psp BOC52_32715 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BOC52_32725 ENOG4105EJC lysr family transcriptional regulator BOC52_32740 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr BOC52_32795 ENOG4108R85 Short chain dehydrogenase BOC52_32800 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BOC52_32820 ENOG4107S74 Lysophospholipid transporter LplT BOC52_32845 ENOG4107S2Z UPF0761 membrane protein BOC52_32850 ENOG4105CS1 NAD(P)H quinone oxidoreductase BOC52_32860 ENOG4105CQB FAD linked oxidase domain protein BOC52_32875 ENOG4105CR8 Transcriptional regulator BOC52_32910 ENOG4105C8Q Methyl-accepting chemotaxis BOC52_32915 ENOG4105EU0 Major facilitator Superfamily BOC52_32920 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BOC52_32925 ENOG4105C4R Atp-dependent dna helicase BOC52_32930 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BOC52_32935 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BOC52_32945 ENOG4105BZU Histidine kinase BOC52_32955 ENOG4108KXV response regulator BOC52_32965 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) BOC52_32975 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BOC52_32985 ENOG4108PSC Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity) BOC52_32995 ENOG41062B0 ABC transporter, permease BOC52_33000 ENOG4105C2J ABC transporter BOC52_33010 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BOC52_33020 ENOG4105DH8 myo-inositol catabolism BOC52_33025 ENOG4108IV0 ABC, transporter BOC52_33030 ENOG4105C0Z ABC transporter BOC52_33035 ENOG4105C32 Amino acid ABC transporter (Permease) BOC52_33065 ENOG4105E09 nadh pyrophosphatase BOC52_33075 ENOG4105C0H protease BOC52_33085 ENOG4105CBP Major Facilitator BOC52_33090 ENOG4105EGI Transcriptional regulator BOC52_33100 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BOC52_33110 ENOG4105CX6 glutaminyL-tRNA synthetase BOC52_33120 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BOC52_33150 ENOG4105CA0 peroxidase BOC52_33170 ENOG4105CW7 secretion protein, HlyD family BOC52_33180 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_33185 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BOC52_33195 ENOG41068CG regulatoR BOC52_33200 ENOG4105BZU Histidine kinase BOC52_33250 ENOG4105DND Transcriptional regulator BOC52_33255 ENOG4107RGD Major Facilitator superfamily BOC52_33395 ENOG4105CS6 Rhs element vgr protein BOC52_33525 ENOG4105RQ9 TPR repeat-containing protein BOC52_33560 ENOG4105S66 prophage protein BOC52_33570 ENOG4105XJC Two component transcriptional regulator (Winged helix family BOC52_33575 ENOG4108KB2 LysR family Transcriptional regulator BOC52_33625 ENOG4105EP6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity) BOC52_33630 ENOG4105CG3 alpha amylase, catalytic region BOC52_33680 ENOG4105JQZ Methyltransferase BOC52_33720 ENOG41067CV Integrase BOC52_33770 ENOG4108K5P (LipO)protein BOC52_33795 ENOG4107R73 Mate efflux family protein BOC52_33870 ENOG4105C9X ppx gppa phosphatase BOC52_33875 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BOC52_33885 ENOG4105BZU Histidine kinase BOC52_33890 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BOC52_33905 ENOG4105E2Z phosphate ABC transporter (Permease BOC52_33910 ENOG4105C8U phosphate abc transporter BOC52_33915 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BOC52_33930 ENOG4105EEI dihydropteroate synthase BOC52_33935 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BOC52_33945 ENOG4105HBR Rna-binding protein BOC52_33955 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BOC52_33960 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BOC52_33965 ENOG4108NIW Leucine export protein LeuE BOC52_33970 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BOC52_34000 ENOG4105E9H Lytic Murein transglycosylase BOC52_34005 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BOC52_34010 ENOG4105D1A Methyltransferase BOC52_34015 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BOC52_34020 ENOG4107RZZ dna polymerase iii epsilon subunit BOC52_34040 ENOG4105CSH Transporter BOC52_34085 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase BOC52_34090 ENOG4105R5N Phosphoribosyl-dephospho-CoA transferase BOC52_34105 ENOG4108459 Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) BOC52_34145 ENOG4105C0M Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity) BOC52_34185 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BOC52_34220 ENOG4105CBN LysR family transcriptional regulator BOC52_34240 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BOC52_34250 ENOG4105F7P transcriptional regulator AsnC family BOC52_34280 ENOG4105BZU Histidine kinase BOC52_34320 ENOG4105ETE Transcriptional regulator (LacI family BOC52_34325 ENOG4107QKW extracellular solute-binding protein family 1 BOC52_34330 ENOG4108I5D sulfate abc transporter BOC52_34345 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BOC52_34355 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BOC52_34365 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BOC52_34385 ENOG4105EQ0 Major Facilitator superfamily BOC52_34395 ENOG4105FDR Membrane BOC52_34410 ENOG4105EQW The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) BOC52_34415 ENOG4108S1C Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) BOC52_34480 ENOG4105BZU Histidine kinase BOC52_34485 ENOG4108YZN class I peptide chain release factor BOC52_34490 ENOG4107QYX exodeoxyribonuclease v alpha BOC52_34495 ENOG4107QKA exodeoxyribonuclease V beta BOC52_34500 ENOG4105DSY exodeoxyribonuclease V, gamma BOC52_34515 ENOG4105EM2 membrane BOC52_34525 ENOG4105C85 amino acid BOC52_34545 ENOG4105F38 ABC transporter, permease BOC52_34550 ENOG4108UCS ABC, transporter BOC52_34555 ENOG4108XM1 transcriptional regulator AsnC family BOC52_34575 ENOG4108Z40 Transcriptional regulator BOC52_34610 ENOG4105BZS acriflavin resistance protein BOC52_34615 ENOG4105BZS acriflavin resistance protein BOC52_34640 ENOG4105BZU Histidine kinase BOC52_34650 ENOG4106RE7 Cytochrome BOC52_34655 ENOG4107RQ2 Cytochrome c oxidase, subunit I BOC52_34670 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding BOC52_34675 ENOG41090Y2 cytochrome C BOC52_34705 ENOG4105GVF (ABC) transporter BOC52_34725 ENOG4108JQ1 Dehydrogenase BOC52_34730 ENOG4108R6W Transcriptional regulator, ARAC family BOC52_34745 ENOG4105DC7 peptidase M24 BOC52_34815 ENOG4105D1Q UPF0246 protein BOC52_34825 ENOG4105CHM Aminotransferase BOC52_34835 ENOG4108UKI Enoyl-CoA hydratase BOC52_34840 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BOC52_34850 ENOG4105C1G acyl-Coa dehydrogenase BOC52_34870 ENOG4105DXM phenylacetic acid degradation protein BOC52_34875 ENOG4105C1G acyl-Coa dehydrogenase BOC52_34880 ENOG4105CC9 acyl-Coa dehydrogenase BOC52_34900 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BOC52_34905 ENOG4105C8S subunit m BOC52_34920 ENOG4105DF2 NADH dehydrogenase subunit j BOC52_34930 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) BOC52_34935 ENOG4108IEH NADH dehydrogenase subunit g BOC52_34945 ENOG4105GKE subunit e BOC52_34975 ENOG4107EJC Preprotein translocase subunit SecG BOC52_34980 ENOG4105CP7 Triose-phosphate isomerase BOC52_35005 ENOG4105ES9 amino acid BOC52_35020 ENOG41077A9 carbonic anhydrase BOC52_35025 ENOG4105CHH sulfate transporter BOC52_35040 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BOC52_35055 ENOG4108ZP8 Acetolactate synthase small subunit BOC52_35060 ENOG4105C7K acetolactate synthase BOC52_35090 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) BOC52_35095 ENOG41080IJ Diacylglycerol kinase BOC52_35100 ENOG41062JF Transcriptional regulator BOC52_35105 ENOG4108URH decarboxylase BOC52_35110 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BOC52_35120 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BOC52_35125 ENOG4105CSH Transporter BOC52_35130 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BOC52_35140 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BOC52_35160 ENOG4105KPY Small multidrug resistance protein BOC52_35170 ENOG4105EEX Two component transcriptional regulator (Winged helix family BOC52_35175 ENOG4105C08 Histidine kinase BOC52_35190 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) BOC52_35210 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BOC52_35225 ENOG41090TK Short-chain dehydrogenase reductase Sdr BOC52_35245 ENOG4105C12 Phosphoribosylglycinamide synthetase BOC52_35260 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BOC52_35270 ENOG4108Z03 MAF-like protein BOC52_35275 ENOG4105C03 ribonuclease BOC52_35285 ENOG4105C2W permease BOC52_35340 ENOG4108KPJ rna polymerase sigma factor BOC52_35350 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BOC52_35385 ENOG4106WTF Glycosyl transferase, family 2 BOC52_35395 ENOG4105DKP glycosyl transferase, family 9 BOC52_35400 ENOG4107XU6 Glycosyl transferase (Group 1 BOC52_35420 ENOG4105BZ1 (ABC) transporter BOC52_35440 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) BOC52_35445 ENOG4105C1J atp-dependent rna helicase BOC52_35455 ENOG41069B0 Membrane-bound lysozyme-inhibitor of c-type lysozyme BOC52_35495 ENOG4105BZP glycoside hydrolase 15-related BOC52_35505 ENOG4108W9H Tetr family transcriptional regulator BOC52_35515 ENOG4105CSM endonuclease III BOC52_35530 ENOG41090Y2 cytochrome C BOC52_35535 ENOG4106RE7 Cytochrome BOC52_35550 ENOG4105DKK Benzoate BOC52_35565 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase BOC52_35580 ENOG41082K6 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BOC52_35600 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BOC52_35610 ENOG4105T38 integral membrane protein BOC52_35615 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BOC52_35625 ENOG4105JAB phenazine biosynthesis protein, phzf family BOC52_35630 ENOG4105BZU Histidine kinase BOC52_35655 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BOC52_35660 ENOG4105CSH Transporter BOC52_35670 ENOG4105DND Transcriptional regulator BOC52_35680 ENOG4105HEI LysR family (Transcriptional regulator BOC52_35705 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BOC52_35710 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BOC52_35715 ENOG4105C5H ABC transporter BOC52_35725 ENOG4105VCQ rubredoxin BOC52_35745 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BOC52_35825 ENOG4105EQR Transposase IS116 IS110 IS902 BOC52_35830 ENOG4105KAK Plasmid pRiA4b ORF-3 family protein BOC52_35835 ENOG4105E5H Transposase BOC52_35840 ENOG4108YXQ IS66 Orf2 family protein BOC52_35910 ENOG41061WM D-Alanyl-D-Alanine BOC52_35950 ENOG4108V1U phospholipid-binding protein BOC52_35955 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_35975 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase BOC52_36035 ENOG4105F7F Chaperone BOC52_36040 ENOG4107Y60 (LipO)protein BOC52_36050 ENOG4106B0W Curli production assembly transport component CsgG BOC52_36105 ENOG4105F38 ABC transporter, permease BOC52_36120 ENOG4105E0F Histidine kinase BOC52_36145 ENOG4105E89 ABC transporter BOC52_36150 ENOG4105DSP amino acid AbC transporter BOC52_36155 ENOG4106YG3 ABC transporter BOC52_36160 ENOG4108JEH abc transporter atp-binding protein BOC52_36165 ENOG4108Z9W Outer membrane porin BOC52_36170 ENOG4108YZA Nitrogen regulatory protein pii BOC52_36175 ENOG4105C4K Nad synthetase BOC52_36200 ENOG41082IR Excinuclease ABC C subunit domain protein BOC52_36205 ENOG4105F0N pyrophosphate phospho-hydrolase BOC52_36220 ENOG4105CSP Major Facilitator Superfamily BOC52_36235 ENOG41076E6 Uroporphyrinogen-III Synthase BOC52_36260 ENOG4105F2W methyltransferase BOC52_36300 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 BOC52_36310 ENOG4105CXN decarboxylase BOC52_36325 ENOG4105D1F ATP-binding protein BOC52_36355 ENOG4105MA0 exported protein BOC52_36360 ENOG4105CFU surface antigen BOC52_36370 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BOC52_36395 ENOG4105D1F ATP-binding protein BOC52_36405 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BOC52_36410 ENOG4108YZT Adenosylcobinamide kinase BOC52_36415 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) BOC52_36420 ENOG4105EFT decarboxylase BOC52_36425 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BOC52_36440 ENOG4108UHF Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) BOC52_36445 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) BOC52_36455 ENOG4108ESU Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity) BOC52_36460 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BOC52_36470 ENOG4107YUN Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) BOC52_36495 ENOG4106NZI LysR family Transcriptional regulator BOC52_36510 ENOG4105W2Z cytochrome C, class I BOC52_36520 ENOG4105MYG DNA polymerase iii, chi subunit BOC52_36530 ENOG4108M8S permease YjgP YjgQ family protein BOC52_36545 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BOC52_36550 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) BOC52_36575 ENOG4107R11 Transcriptional regulator BOC52_36670 ENOG4108S8N class II Aldolase BOC52_36675 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BOC52_36680 ENOG4108RPX mosc domain containing protein BOC52_36685 ENOG4105D74 hydrolase BOC52_36695 ENOG4105HEI LysR family (Transcriptional regulator BOC52_36720 ENOG4108EX3 reductase BOC52_36725 ENOG4105C8Y Acetylornithine aminotransferase BOC52_36730 ENOG4108R6G acetyltransferase BOC52_36745 ENOG4108IV0 ABC, transporter BOC52_36750 ENOG4105C0Z ABC transporter BOC52_36755 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BOC52_36760 ENOG4105C32 Amino acid ABC transporter (Permease) BOC52_36770 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BOC52_36775 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BOC52_36795 ENOG4108IYU L-aspartate oxidase BOC52_36805 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BOC52_36820 ENOG4105EGS Mechanosensitive ion channel BOC52_36830 ENOG4108V3E phosphoribosylglycinamide formyltransferase BOC52_36835 ENOG4105DTN riboflavin biosynthesis protein ribF BOC52_36840 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BOC52_36850 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BOC52_36870 ENOG4105C85 amino acid BOC52_36875 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BOC52_36885 ENOG4105VEQ Cold shock protein BOC52_36905 ENOG4108R99 pseudouridine synthase BOC52_36920 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BOC52_36955 ENOG4105CV8 reductase BOC52_36960 ENOG4105FDP GntR family transcriptional regulator BOC52_36970 ENOG4105BZN citrate synthase BOC52_36980 ENOG4105C0R drug resistance transporter emrb qaca subfamily BOC52_37040 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BOC52_37045 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BOC52_37055 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) BOC52_37095 ENOG4105CJR Integral membrane protein (MviN