locus-tag	class	description
WT60_00010	COG0592	DNA-directed DNA polymerase activity
WT60_00030	COG0753	catalase activity
WT60_00085	COG1024	Enoyl-CoA hydratase
WT60_00085	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT60_00090	COG0183	Belongs to the thiolase family
WT60_00095	COG1960	acyl-CoA dehydrogenase activity
WT60_00120	COG1695	Transcriptional regulator
WT60_00215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_00230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_00245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT60_00255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WT60_00265	COG1987	bacterial-type flagellum assembly
WT60_00295	COG1346	cytolysis
WT60_00305	COG0583	DNA-binding transcription factor activity
WT60_00310	COG2814	Major facilitator Superfamily
WT60_00315	COG1846	Transcriptional regulator
WT60_00400	COG0741	lytic transglycosylase activity
WT60_00405	COG0523	cobalamin synthesis protein
WT60_00440	COG0519	Catalyzes the synthesis of GMP from XMP
WT60_00440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WT60_00445	COG1902	pentaerythritol trinitrate reductase activity
WT60_00455	COG0642	Histidine kinase
WT60_00465	COG2154	pterin-4-alpha-carbinolamine dehydratase
WT60_00470	COG3186	Phenylalanine-4-hydroxylase
WT60_00475	COG1522	sequence-specific DNA binding
WT60_00490	COG0583	DNA-binding transcription factor activity
WT60_00505	COG0411	ABC transporter
WT60_00520	COG0559	Belongs to the binding-protein-dependent transport system permease family
WT60_00545	COG0411	ABC transporter
WT60_00565	COG1192	Involved in chromosome partitioning
WT60_00570	COG1475	DNA binding
WT60_00575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WT60_00585	COG0356	it plays a direct role in the translocation of protons across the membrane
WT60_00595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WT60_00610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WT60_00615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WT60_00625	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_00630	COG1832	CoA-binding protein
WT60_00645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WT60_00650	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WT60_00650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WT60_00650	COG0506	proline dehydrogenase activity
WT60_00665	COG1960	acyl-CoA dehydrogenase activity
WT60_00675	COG0436	Aminotransferase
WT60_00685	COG0277	FAD linked oxidase domain protein
WT60_00695	COG0789	Transcriptional regulator
WT60_00710	COG0668	transmembrane transport
WT60_00725	COG0531	amino acid
WT60_00730	COG4303	Ethanolamine ammonia lyase large subunit
WT60_00735	COG4302	ethanolamine ammonia-lyase activity
WT60_00740	COG1012	belongs to the aldehyde dehydrogenase family
WT60_00745	COG2207	Transcriptional regulator
WT60_00755	COG0028	Belongs to the TPP enzyme family
WT60_00765	COG1760	l-serine dehydratase
WT60_00785	COG0509	glycine decarboxylation via glycine cleavage system
WT60_00800	COG0673	inositol 2-dehydrogenase activity
WT60_00810	COG0210	DNA helicase
WT60_00815	COG3245	cytochrome
WT60_00875	COG0582	viral genome integration into host DNA
WT60_00890	COG4372	Transposase
WT60_00895	COG3436	PFAM IS66 Orf2 family protein
WT60_00915	COG2801	Transposase and inactivated derivatives
WT60_00920	COG2963	transposase activity
WT60_00930	COG0270	DNA (cytosine-5-)-methyltransferase activity
WT60_00960	COG3436	PFAM IS66 Orf2 family protein
WT60_00965	COG4372	Transposase
WT60_00980	COG3547	Transposase (IS116 IS110 IS902 family)
WT60_01015	COG4372	Transposase
WT60_01020	COG3436	PFAM IS66 Orf2 family protein
WT60_01030	COG3397	chitin binding
WT60_01045	COG0840	transmembrane signaling receptor activity
WT60_01050	COG0596	Alpha beta hydrolase
WT60_01125	COG0519	Catalyzes the synthesis of GMP from XMP
WT60_01140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WT60_01150	COG0438	transferase activity, transferring glycosyl groups
WT60_01175	COG2201	protein-glutamate methylesterase activity
WT60_01195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WT60_01210	COG0745	RESPONSE REGULATOR receiver
WT60_01215	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WT60_01240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT60_01245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT60_01255	COG2894	cell division
WT60_01260	COG1191	sigma factor activity
WT60_01270	COG1950	PFAM Membrane protein of
WT60_01275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WT60_01290	COG2070	2-Nitropropane dioxygenase
WT60_01300	COG2223	nitrite transmembrane transporter activity
WT60_01320	COG1522	sequence-specific DNA binding
WT60_01330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WT60_01350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WT60_01355	COG2823	Periplasmic or secreted lipoprotein
WT60_01370	COG1113	amino acid transport
WT60_01380	COG1120	ATPase activity
WT60_01385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WT60_01390	COG2819	hydrolase of the alpha beta superfamily
WT60_01405	COG4771	TonB-dependent receptor
WT60_01410	COG1169	isochorismate synthase
WT60_01415	COG1021	2,3-dihydroxybenzoate-AMP ligase
WT60_01420	COG1535	isochorismatase
WT60_01420	COG3433	isochorismatase activity
WT60_01430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT60_01435	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_01440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WT60_01470	COG2084	Dehydrogenase
WT60_01475	COG1280	lysine exporter protein (LysE YggA)
WT60_01490	COG3047	cAMP biosynthetic process
WT60_01505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WT60_01515	COG1881	PFAM PEBP family protein
WT60_01520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WT60_01525	COG0280	phosphate acetyltransferase
WT60_01525	COG0281	malic enzyme
WT60_01550	COG1522	sequence-specific DNA binding
WT60_01570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WT60_01575	COG2151	metal-sulfur cluster biosynthetic enzyme
WT60_01580	COG3396	Phenylacetate-CoA oxygenase
WT60_01585	COG3460	Phenylacetate-CoA oxygenase
WT60_01590	COG3396	Phenylacetate-CoA oxygenase
WT60_01630	COG2801	Transposase and inactivated derivatives
WT60_01635	COG2963	transposase activity
WT60_01665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WT60_01685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WT60_01710	COG0514	ATP-dependent DNA helicase (RecQ)
WT60_01720	COG0049	tRNA binding
WT60_01725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WT60_01755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WT60_01770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WT60_01790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WT60_01825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WT60_01840	COG0201	protein transport
WT60_01875	COG0203	ribosomal protein L17
WT60_01885	COG4232	protein-disulfide reductase activity
WT60_01895	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WT60_01905	COG1333	cytochrome c biogenesis protein
WT60_01910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WT60_01915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WT60_01920	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WT60_01975	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WT60_01985	COG1175	transmembrane transport
WT60_01990	COG0395	ABC-type sugar transport system, permease component
WT60_02000	COG0584	glycerophosphoryl diester phosphodiesterase
WT60_02015	COG0069	glutamate synthase activity
WT60_02015	COG0070	glutamate synthase
WT60_02015	COG0067	glutamate synthase
WT60_02025	COG1115	amino acid carrier protein
WT60_02045	COG4178	(ABC) transporter
WT60_02060	COG2022	thiamine diphosphate biosynthetic process
WT60_02070	COG1127	ABC transporter
WT60_02075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WT60_02080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WT60_02100	COG1131	(ABC) transporter
WT60_02105	COG0842	Transport permease protein
WT60_02125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WT60_02130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WT60_02140	COG2095	MarC family integral membrane protein
WT60_02145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WT60_02190	COG0805	protein transport
WT60_02195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT60_02200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WT60_02205	COG0723	plastoquinol--plastocyanin reductase activity
WT60_02210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WT60_02215	COG2857	Cytochrome c1
WT60_02220	COG0625	glutathione transferase activity
WT60_02225	COG2969	positive regulation of protein catabolic process
WT60_02235	COG0582	viral genome integration into host DNA
WT60_02305	COG5377	YqaJ viral recombinase family
WT60_02360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WT60_02370	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WT60_02555	COG0308	aminopeptidase N
WT60_02600	COG0443	Heat shock 70 kDa protein
WT60_02605	COG1278	Cold shock
WT60_02610	COG0531	amino acid
WT60_02615	COG3384	dioxygenase
WT60_02625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WT60_02630	COG2890	protein-(glutamine-N5) methyltransferase activity
WT60_02655	COG0006	proline dipeptidase activity
WT60_02660	COG1335	isochorismatase
WT60_02675	COG0488	(ABC) transporter
WT60_02710	COG0012	GTP binding
WT60_02720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WT60_02725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WT60_02735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WT60_02740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WT60_02760	COG0512	Glutamine amidotransferase of anthranilate synthase
WT60_02770	COG0546	phosphoglycolate phosphatase activity
WT60_02780	COG2967	ApaG domain
WT60_02785	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WT60_02795	COG2050	protein possibly involved in aromatic compounds catabolism
WT60_02800	COG1024	Enoyl-CoA hydratase
WT60_02815	COG1024	Enoyl-CoA hydratase
WT60_02850	COG3436	PFAM IS66 Orf2 family protein
WT60_02855	COG4372	Transposase
WT60_02870	COG0243	molybdopterin cofactor binding
WT60_02875	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_02880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_02900	COG3116	cell division
WT60_02910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WT60_02915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WT60_02950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WT60_02965	COG0678	peroxiredoxin activity
WT60_02995	COG0494	nUDIX hydrolase
WT60_03000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WT60_03015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WT60_03025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WT60_03030	COG4536	flavin adenine dinucleotide binding
WT60_03040	COG4372	Transposase
WT60_03045	COG3436	PFAM IS66 Orf2 family protein
WT60_03090	COG0270	DNA (cytosine-5-)-methyltransferase activity
WT60_03110	COG3436	PFAM IS66 Orf2 family protein
WT60_03115	COG4372	Transposase
WT60_03130	COG0142	geranyltranstransferase activity
WT60_03140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WT60_03170	COG2095	MarC family integral membrane protein
WT60_03180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WT60_03225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WT60_03240	COG0439	Biotin carboxylase
WT60_03245	COG0511	ligase activity, forming carbon-carbon bonds
WT60_03250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WT60_03255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WT60_03265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WT60_03270	COG3150	esterase
WT60_03275	COG0557	exoribonuclease II activity
WT60_03280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WT60_03300	COG1414	Transcriptional regulator
WT60_03305	COG3734	2-keto-3-deoxy-galactonokinase
WT60_03315	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_03330	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_03335	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_03345	COG0284	orotidine-5'-phosphate decarboxylase activity
WT60_03350	COG1546	Belongs to the CinA family
WT60_03355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WT60_03380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WT60_03390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WT60_03395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WT60_03400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WT60_03410	COG2814	Major facilitator Superfamily
WT60_03425	COG0583	DNA-binding transcription factor activity
WT60_03435	COG1301	dicarboxylic acid transport
WT60_03440	COG4266	Belongs to the allantoicase family
WT60_03445	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
WT60_03450	COG0735	belongs to the Fur family
WT60_03455	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WT60_03510	COG0800	Aldolase
WT60_03520	COG3265	gluconokinase activity
WT60_03530	COG2223	nitrite transmembrane transporter activity
WT60_03535	COG0583	DNA-binding transcription factor activity
WT60_03540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WT60_03545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT60_03550	COG0765	amino acid transport
WT60_03555	COG0765	amino acid transport
WT60_03560	COG1126	abc transporter atp-binding protein
WT60_03565	COG0121	glutamine amidotransferase
WT60_03570	COG0418	dihydroorotase activity
WT60_03600	COG1917	Cupin 2, conserved barrel domain protein
WT60_03600	COG4977	sequence-specific DNA binding
WT60_03605	COG0625	glutathione transferase activity
WT60_03610	COG0625	glutathione transferase activity
WT60_03620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WT60_03630	COG0588	phosphoglycerate mutase activity
WT60_03660	COG0138	bifunctional purine biosynthesis protein purh
WT60_03665	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WT60_03675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WT60_03680	COG0006	proline dipeptidase activity
WT60_03690	COG0625	glutathione transferase activity
WT60_03695	COG0069	glutamate synthase activity
WT60_03710	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WT60_03715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WT60_03720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WT60_03770	COG3008	intermembrane lipid transfer
WT60_03770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WT60_03775	COG2995	paraquat-inducible protein a
WT60_03790	COG3038	cytochrome b561
WT60_03795	COG2353	YceI-like domain
WT60_03800	COG2353	YceI-like domain
WT60_03805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WT60_03810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WT60_03815	COG1862	Preprotein translocase
WT60_03830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WT60_03855	COG0783	Belongs to the Dps family
WT60_03875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT60_03885	COG2771	luxR family
WT60_03900	COG0436	Aminotransferase
WT60_03925	COG0247	lactate metabolic process
WT60_03930	COG0277	FAD linked oxidase domain protein
WT60_03935	COG0277	FAD linked oxidase domain protein
WT60_03940	COG0277	FAD linked oxidase domain protein
WT60_03945	COG2096	Adenosyltransferase
WT60_03950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WT60_03950	COG1017	nitric oxide dioxygenase activity
WT60_03960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WT60_03965	COG0312	modulator of DNA gyrase
WT60_03970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WT60_03975	COG3164	Protein of unknown function
WT60_03980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WT60_03985	COG0497	DNA recombination
WT60_03990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WT60_04030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WT60_04040	COG1428	Deoxynucleoside kinase
WT60_04050	COG0617	tRNA 3'-terminal CCA addition
WT60_04060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WT60_04080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WT60_04085	COG0586	Pfam SNARE associated Golgi protein
WT60_04095	COG3012	SEC-C Motif Domain Protein
WT60_04105	COG3436	PFAM IS66 Orf2 family protein
WT60_04185	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WT60_04195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WT60_04240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WT60_04245	COG0156	8-amino-7-oxononanoate synthase activity
WT60_04285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WT60_04290	COG0489	protein tyrosine kinase activity
WT60_04290	COG3206	protein involved in exopolysaccharide biosynthesis
WT60_04300	COG3562	capsule polysaccharide
WT60_04305	COG1045	serine acetyltransferase
WT60_04320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WT60_04330	COG0517	IMP dehydrogenase activity
WT60_04330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WT60_04335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WT60_04355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WT60_04405	COG4221	oxidoreductase activity
WT60_04460	COG0450	alkyl hydroperoxide reductase
WT60_04465	COG1960	acyl-CoA dehydrogenase activity
WT60_04520	COG2814	Major facilitator Superfamily
WT60_04525	COG0778	Nitroreductase
WT60_04530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT60_04535	COG0583	DNA-binding transcription factor activity
WT60_04555	COG2814	Major facilitator Superfamily
WT60_04560	COG0778	Nitroreductase
WT60_04565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT60_04570	COG0583	DNA-binding transcription factor activity
WT60_04575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WT60_04590	COG2814	Major facilitator Superfamily
WT60_04600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WT60_04615	COG4774	siderophore transport
WT60_04620	COG1120	ATPase activity
WT60_04630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WT60_04670	COG0730	response to heat
WT60_04685	COG1280	lysine exporter protein (LysE YggA)
WT60_04745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WT60_04760	COG1773	rubredoxin
WT60_04770	COG1678	Uncharacterized ACR, COG1678
WT60_04780	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
WT60_04845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WT60_04855	COG3754	Rhamnan synthesis protein F
WT60_04875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WT60_04890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WT60_04915	COG0859	PFAM glycosyl transferase family 9
WT60_04980	COG0559	Belongs to the binding-protein-dependent transport system permease family
WT60_05000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WT60_05010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WT60_05080	COG0762	integral membrane protein
WT60_05120	COG0436	Aminotransferase
WT60_05145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WT60_05145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WT60_05165	COG2814	Major facilitator Superfamily
WT60_05175	COG1126	abc transporter atp-binding protein
WT60_05185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT60_05190	COG0837	glucose binding
WT60_05190	COG1737	Transcriptional regulator
WT60_05195	COG0363	glucosamine-6-phosphate deaminase activity
WT60_05200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WT60_05220	COG3842	ATPase activity
WT60_05225	COG2860	membrane
WT60_05230	COG1193	negative regulation of DNA recombination
WT60_05235	COG0492	ferredoxin-NADP+ reductase activity
WT60_05240	COG1674	ftsk spoiiie
WT60_05250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WT60_05285	COG2894	cell division
WT60_05305	COG0859	PFAM glycosyl transferase family 9
WT60_05315	COG0477	Major facilitator Superfamily
WT60_05350	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WT60_05355	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WT60_05360	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WT60_05365	COG0745	RESPONSE REGULATOR receiver
WT60_05370	COG1215	transferase activity, transferring glycosyl groups
WT60_05375	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WT60_05400	COG1215	transferase activity, transferring glycosyl groups
WT60_05405	COG2194	sulfuric ester hydrolase activity
WT60_05420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WT60_05425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WT60_05435	COG1561	YicC-like family, N-terminal region
WT60_05440	COG0194	GDP metabolic process
WT60_05450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WT60_05470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_05480	COG1278	Cold shock
WT60_05485	COG2176	DNA-directed DNA polymerase activity
WT60_05500	COG4772	TonB-dependent receptor
WT60_05545	COG0583	DNA-binding transcription factor activity
WT60_05560	COG0308	aminopeptidase N
WT60_05570	COG2119	membrane
WT60_05575	COG0402	S-adenosylhomocysteine deaminase activity
WT60_05580	COG2252	PERMEase
WT60_05585	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WT60_05595	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WT60_05600	COG0154	amidase activity
WT60_05615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WT60_05640	COG3383	formate dehydrogenase (NAD+) activity
WT60_05655	COG1910	domain protein
WT60_05665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WT60_05700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WT60_05705	COG1605	Chorismate mutase
WT60_05705	COG0077	Prephenate dehydratase
WT60_05710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WT60_05735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WT60_05745	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WT60_05765	COG2951	lytic endotransglycosylase activity
WT60_05770	COG0123	including yeast histone deacetylase and acetoin utilization protein
WT60_05775	COG2267	carboxylic ester hydrolase activity
WT60_05780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WT60_05785	COG2011	ABC-type metal ion transport system permease component
WT60_05805	COG1960	acyl-CoA dehydrogenase activity
WT60_05815	COG1522	sequence-specific DNA binding
WT60_05880	COG0501	Belongs to the peptidase M48B family
WT60_05890	COG0521	Mo-molybdopterin cofactor biosynthetic process
WT60_05895	COG3028	Belongs to the UPF0307 family
WT60_05900	COG0312	modulator of DNA gyrase
WT60_05905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WT60_05915	COG2204	response regulator
WT60_05945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WT60_05955	COG0640	Transcriptional regulator
WT60_05960	COG1607	acyl-coa hydrolase
WT60_05970	COG0114	fumarate hydratase activity
WT60_05980	COG0534	Mate efflux family protein
WT60_05985	COG2501	S4 domain
WT60_06015	COG3045	CreA protein
WT60_06030	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WT60_06035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WT60_06070	COG0303	'Molybdopterin
WT60_06080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WT60_06085	COG1530	ribonuclease E activity
WT60_06095	COG0546	phosphoglycolate phosphatase activity
WT60_06105	COG0616	signal peptide processing
WT60_06115	COG0424	maF-like protein
WT60_06120	COG1399	metal-binding, possibly nucleic acid-binding protein
WT60_06155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WT60_06180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT60_06195	COG0681	Belongs to the peptidase S26 family
WT60_06200	COG0571	ribonuclease III activity
WT60_06205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WT60_06215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WT60_06225	COG1472	Belongs to the glycosyl hydrolase 3 family
WT60_06250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WT60_06350	COG1956	GAF domain-containing protein
WT60_06355	COG0583	DNA-binding transcription factor activity
WT60_06385	COG1999	signal sequence binding
WT60_06395	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WT60_06400	COG1132	(ABC) transporter
WT60_06405	COG0438	transferase activity, transferring glycosyl groups
WT60_06420	COG2022	thiamine diphosphate biosynthetic process
WT60_06420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT60_06425	COG0683	leucine binding
WT60_06430	COG3511	phospholipase C
WT60_06440	COG0596	Alpha beta hydrolase
WT60_06445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WT60_06460	COG3394	polysaccharide catabolic process
WT60_06475	COG4215	(ABC) transporter
WT60_06480	COG4160	amino acid transport
WT60_06495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WT60_06525	COG0625	glutathione transferase activity
WT60_06530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT60_06545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WT60_06570	COG1959	2 iron, 2 sulfur cluster binding
WT60_06580	COG2151	metal-sulfur cluster biosynthetic enzyme
WT60_06585	COG0822	iron-sulfur transferase activity
WT60_06590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WT60_06600	COG0396	ATPase activity
WT60_06605	COG0719	Fe-S assembly protein
WT60_06615	COG0840	transmembrane signaling receptor activity
WT60_06620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WT60_06625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WT60_06685	COG2151	metal-sulfur cluster biosynthetic enzyme
WT60_06700	COG0415	Belongs to the DNA photolyase family
WT60_06705	COG0529	Catalyzes the synthesis of activated sulfate
WT60_06725	COG2091	lysine biosynthetic process via aminoadipic acid
WT60_06740	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WT60_06755	COG0402	S-adenosylhomocysteine deaminase activity
WT60_06780	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WT60_06785	COG0174	glutamine synthetase
WT60_06805	COG3501	Rhs element vgr protein
WT60_06840	COG0583	DNA-binding transcription factor activity
WT60_06845	COG1960	acyl-CoA dehydrogenase activity
WT60_06855	COG0477	Major facilitator Superfamily
WT60_06865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WT60_06865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WT60_06870	COG1643	Atp-dependent helicase
WT60_06890	COG1058	Belongs to the CinA family
WT60_06890	COG1546	Belongs to the CinA family
WT60_06905	COG3852	Histidine kinase
WT60_06925	COG2197	response regulator
WT60_06935	COG2181	nitrate reductase activity
WT60_06940	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WT60_06950	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WT60_06955	COG2223	nitrite transmembrane transporter activity
WT60_06970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WT60_06975	COG0339	signal peptide processing
WT60_06985	COG4566	intracellular signal transduction
WT60_06995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WT60_07000	COG0508	dehydrogenase complex catalyzes the overall conversion of
WT60_07005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WT60_07020	COG1414	Transcriptional regulator
WT60_07040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WT60_07050	COG1104	cysteine desulfurase activity
WT60_07055	COG0822	iron-sulfur transferase activity
WT60_07060	COG0316	Belongs to the HesB IscA family
WT60_07095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WT60_07105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WT60_07130	COG0084	hydrolase, TatD family'
WT60_07135	COG2333	competence protein COMEC
WT60_07135	COG0658	competence protein
WT60_07150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WT60_07160	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WT60_07170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WT60_07180	COG2833	Protein of unknown function (DUF455)
WT60_07185	COG0596	Alpha beta hydrolase
WT60_07190	COG0613	PHP domain protein
WT60_07195	COG0009	L-threonylcarbamoyladenylate synthase
WT60_07200	COG1994	Peptidase M50
WT60_07205	COG0180	Tryptophanyl-tRNA synthetase
WT60_07215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WT60_07220	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WT60_07225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WT60_07230	COG2850	peptidyl-arginine hydroxylation
WT60_07245	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WT60_07265	COG1045	serine acetyltransferase
WT60_07270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WT60_07280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WT60_07305	COG0037	tRNA processing
WT60_07310	COG0527	aspartate kinase activity
WT60_07335	COG0024	Methionine aminopeptidase
WT60_07355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WT60_07360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WT60_07375	COG0243	molybdopterin cofactor binding
WT60_07390	COG4166	transmembrane transport
WT60_07395	COG4174	ABC transporter (Permease)
WT60_07400	COG4239	(ABC) transporter, permease
WT60_07405	COG4172	Belongs to the ABC transporter superfamily
WT60_07410	COG0791	NLP P60 protein
WT60_07415	COG1752	Esterase of the alpha-beta hydrolase superfamily
WT60_07475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WT60_07485	COG0583	DNA-binding transcription factor activity
WT60_07495	COG2224	Isocitrate lyase
WT60_07500	COG0513	Belongs to the DEAD box helicase family
WT60_07510	COG1214	PFAM Peptidase M22, glycoprotease
WT60_07520	COG1573	uracil-dna glycosylase
WT60_07530	COG0351	phosphomethylpyrimidine kinase
WT60_07535	COG0477	Major facilitator Superfamily
WT60_07555	COG0488	(ABC) transporter
WT60_07560	COG0386	Belongs to the glutathione peroxidase family
WT60_07575	COG2890	protein-(glutamine-N5) methyltransferase activity
WT60_07585	COG1393	Belongs to the ArsC family
WT60_07620	COG0242	peptide deformylase activity
WT60_07625	COG1187	pseudouridine synthase activity
WT60_07635	COG0024	Methionine aminopeptidase
WT60_07660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WT60_07675	COG0750	zinc metalloprotease
WT60_07715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WT60_07745	COG0330	HflC and HflK could
WT60_07765	COG0697	spore germination
WT60_07805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WT60_07815	COG2207	Transcriptional regulator
WT60_07815	COG1917	Cupin 2, conserved barrel domain protein
WT60_07820	COG2814	Major facilitator Superfamily
WT60_07840	COG0590	tRNA wobble adenosine to inosine editing
WT60_07845	COG1619	proteins homologs of microcin C7 resistance protein MccF
WT60_07855	COG1953	Uracil, thiamine, allantoin
WT60_07870	COG3648	Uricase
WT60_07870	COG3195	allantoin biosynthetic process
WT60_07875	COG4266	Belongs to the allantoicase family
WT60_07895	COG2351	hydroxyisourate hydrolase activity
WT60_07915	COG3360	Dodecin
WT60_07980	COG1024	Enoyl-CoA hydratase
WT60_07985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WT60_08000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WT60_08010	COG2205	protein histidine kinase activity
WT60_08015	COG0745	RESPONSE REGULATOR receiver
WT60_08185	COG3772	lysozyme
WT60_08270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WT60_08275	COG1846	Transcriptional regulator
WT60_08280	COG1929	Belongs to the glycerate kinase type-1 family
WT60_08300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WT60_08340	COG4181	ATPase activity
WT60_08355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT60_08360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WT60_08360	COG0047	phosphoribosylformylglycinamidine synthase activity
WT60_08370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WT60_08395	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_08400	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT60_08400	COG1024	Enoyl-CoA hydratase
WT60_08405	COG1335	isochorismatase
WT60_08410	COG0183	Belongs to the thiolase family
WT60_08435	COG2223	nitrite transmembrane transporter activity
WT60_08440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT60_08460	COG2153	protein acetylation
WT60_08470	COG0354	folic acid binding
WT60_08475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WT60_08490	COG1247	-acetyltransferase
WT60_08495	COG0084	hydrolase, TatD family'
WT60_08520	COG0438	transferase activity, transferring glycosyl groups
WT60_08545	COG0252	asparaginase activity
WT60_08550	COG1652	LysM domain
WT60_08560	COG2084	Dehydrogenase
WT60_08565	COG3622	Belongs to the hyi family
WT60_08570	COG3960	tartronate-semialdehyde synthase activity
WT60_08575	COG0583	DNA-binding transcription factor activity
WT60_08620	COG0305	Participates in initiation and elongation during chromosome replication
WT60_08630	COG0306	phosphate transporter
WT60_08640	COG0791	NLP P60 protein
WT60_08645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WT60_08650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WT60_08655	COG0726	polysaccharide deacetylase
WT60_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT60_08660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WT60_08670	COG0463	Glycosyl transferase, family 2
WT60_08675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WT60_08680	COG2076	Multidrug Resistance protein
WT60_08695	COG0436	Aminotransferase
WT60_08720	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WT60_08725	COG0314	molybdopterin synthase activity
WT60_08730	COG2346	COG2346, Truncated hemoglobins
WT60_08735	COG1959	2 iron, 2 sulfur cluster binding
WT60_08740	COG0542	response to heat
WT60_08765	COG0534	Mate efflux family protein
WT60_08780	COG3228	Belongs to the MtfA family
WT60_08790	COG0789	Transcriptional regulator
WT60_08795	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WT60_08805	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WT60_08820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT60_08855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WT60_08860	COG0670	Belongs to the BI1 family
WT60_08880	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WT60_08895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WT60_08915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WT60_08920	COG0330	HflC and HflK could
WT60_08925	COG0330	HflC and HflK could
WT60_08930	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WT60_08945	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WT60_08950	COG3158	transport of potassium into the cell
WT60_08955	COG2183	response to ionizing radiation
WT60_08970	COG1199	ATP-dependent helicase activity
WT60_08980	COG0564	pseudouridine synthase activity
WT60_08995	COG3243	poly(R)-hydroxyalkanoic acid synthase
WT60_09000	COG0183	Belongs to the thiolase family
WT60_09005	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_09015	COG2076	Multidrug Resistance protein
WT60_09030	COG0183	Belongs to the thiolase family
WT60_09040	COG0626	cystathionine gamma-synthase activity
WT60_09045	COG0560	Phosphoserine phosphatase
WT60_09055	COG0390	transport system, permease component
WT60_09060	COG1122	ATPase activity
WT60_09065	COG2982	Protein involved in outer membrane biogenesis
WT60_09070	COG0488	(ABC) transporter
WT60_09085	COG2070	2-Nitropropane dioxygenase
WT60_09090	COG3047	cAMP biosynthetic process
WT60_09105	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WT60_09110	COG3842	ATPase activity
WT60_09115	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT60_09120	COG1177	transmembrane transport
WT60_09150	COG2211	Major facilitator Superfamily
WT60_09175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WT60_09185	COG0367	asparagine synthase
WT60_09205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_09220	COG0038	chloride channel
WT60_09225	COG2855	membrane
WT60_09245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT60_09250	COG2271	Major facilitator Superfamily
WT60_09255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT60_09260	COG1609	Transcriptional regulator
WT60_09330	COG0598	Magnesium transport protein CorA
WT60_09335	COG2350	Protein conserved in bacteria
WT60_09355	COG3264	Mechanosensitive ion channel
WT60_09355	COG1511	domain protein
WT60_09385	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WT60_09400	COG4263	nitrous-oxide reductase activity
WT60_09445	COG2963	transposase activity
WT60_09450	COG2801	Transposase and inactivated derivatives
WT60_09480	COG4585	Histidine kinase
WT60_09500	COG1012	belongs to the aldehyde dehydrogenase family
WT60_09510	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_09515	COG0129	dihydroxy-acid dehydratase activity
WT60_09550	COG1609	Transcriptional regulator
WT60_09555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_09565	COG0835	chemotaxis
WT60_09580	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_09585	COG0477	Major facilitator Superfamily
WT60_09595	COG2226	methyltransferase
WT60_09600	COG1732	Glycine betaine
WT60_09605	COG1174	glycine betaine transport
WT60_09610	COG1125	glycine betaine transport
WT60_09615	COG1174	glycine betaine transport
WT60_09635	COG2235	arginine
WT60_09640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WT60_09650	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_09660	COG0583	DNA-binding transcription factor activity
WT60_09665	COG0625	glutathione transferase activity
WT60_09670	COG1846	Transcriptional regulator
WT60_09675	COG2807	transmembrane transport
WT60_09685	COG1649	PFAM Uncharacterised BCR, COG1649
WT60_09700	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
WT60_09710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WT60_09730	COG3979	chitinase
WT60_09750	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
WT60_09770	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WT60_09805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WT60_09810	COG4774	siderophore transport
WT60_09815	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WT60_09850	COG1120	ATPase activity
WT60_09880	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_09890	COG1063	alcohol dehydrogenase
WT60_09900	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_09910	COG1879	ABC-type sugar transport system periplasmic component
WT60_09930	COG1132	(ABC) transporter
WT60_09940	COG3121	Chaperone
WT60_09965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_09975	COG1309	transcriptional regulator
WT60_09980	COG0739	heme binding
WT60_10040	COG4964	Belongs to the GSP D family
WT60_10060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT60_10065	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WT60_10075	COG0477	Major facilitator Superfamily
WT60_10080	COG2719	SpoVR family
WT60_10085	COG2718	Belongs to the UPF0229 family
WT60_10090	COG2766	serine protein kinase
WT60_10095	COG0840	transmembrane signaling receptor activity
WT60_10100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT60_10105	COG1609	Transcriptional regulator
WT60_10110	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_10120	COG1879	ABC-type sugar transport system periplasmic component
WT60_10130	COG0583	DNA-binding transcription factor activity
WT60_10135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WT60_10140	COG4208	sulfate ABC transporter
WT60_10145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WT60_10150	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WT60_10190	COG0701	Predicted permease
WT60_10195	COG0667	Aldo Keto reductase
WT60_10205	COG1733	regulation of RNA biosynthetic process
WT60_10210	COG1301	dicarboxylic acid transport
WT60_10245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT60_10315	COG0673	inositol 2-dehydrogenase activity
WT60_10320	COG1802	Transcriptional regulator
WT60_10330	COG3023	N-Acetylmuramoyl-L-alanine amidase
WT60_10335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WT60_10340	COG0557	exoribonuclease II activity
WT60_10375	COG0519	Catalyzes the synthesis of GMP from XMP
WT60_10380	COG2814	Major facilitator Superfamily
WT60_10390	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_10455	COG4964	Belongs to the GSP D family
WT60_10505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WT60_10510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WT60_10515	COG0508	dehydrogenase complex catalyzes the overall conversion of
WT60_10520	COG0567	Dehydrogenase, E1 component
WT60_10530	COG1846	Transcriptional regulator
WT60_10540	COG1566	PFAM secretion protein HlyD family protein
WT60_10545	COG2814	Major facilitator Superfamily
WT60_10550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WT60_10565	COG0195	Participates in both transcription termination and antitermination
WT60_10565	COG2251	uridine kinase activity
WT60_10575	COG1187	pseudouridine synthase activity
WT60_10580	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WT60_10585	COG0583	DNA-binding transcription factor activity
WT60_10625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WT60_10655	COG0776	regulation of translation
WT60_10680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WT60_10695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WT60_10700	COG0251	oxidation-reduction process
WT60_10740	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_10755	COG0477	Major facilitator Superfamily
WT60_10770	COG1295	ribonuclease BN
WT60_10785	COG0277	FAD linked oxidase domain protein
WT60_10795	COG0583	DNA-binding transcription factor activity
WT60_10820	COG0840	transmembrane signaling receptor activity
WT60_10825	COG2223	nitrite transmembrane transporter activity
WT60_10830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WT60_10835	COG0210	DNA helicase
WT60_10840	COG0525	valine-tRNA ligase activity
WT60_10845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WT60_10855	COG5002	protein histidine kinase activity
WT60_10865	COG0745	RESPONSE REGULATOR receiver
WT60_10875	COG0425	Belongs to the sulfur carrier protein TusA family
WT60_10880	COG0673	inositol 2-dehydrogenase activity
WT60_10885	COG0673	inositol 2-dehydrogenase activity
WT60_10900	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_10910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT60_10915	COG3962	Belongs to the TPP enzyme family
WT60_10925	COG3718	enzyme involved in inositol metabolism
WT60_10935	COG0411	ABC transporter
WT60_10940	COG0559	Belongs to the binding-protein-dependent transport system permease family
WT60_10945	COG0824	Thioesterase
WT60_10965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT60_10970	COG0477	Major facilitator Superfamily
WT60_10990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT60_11000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WT60_11005	COG1051	belongs to the nudix hydrolase family
WT60_11025	COG1858	cytochrome C peroxidase
WT60_11030	COG3511	phospholipase C
WT60_11045	COG2197	response regulator
WT60_11085	COG0583	DNA-binding transcription factor activity
WT60_11100	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT60_11130	COG3328	transposase activity
WT60_11145	COG3501	Rhs element vgr protein
WT60_11170	COG3501	Rhs element vgr protein
WT60_11235	COG3501	Rhs element vgr protein
WT60_11300	COG2885	chlorophyll binding
WT60_11315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WT60_11345	COG4942	peptidase
WT60_11350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WT60_11365	COG0534	Mate efflux family protein
WT60_11530	COG1802	Transcriptional regulator
WT60_11530	COG4626	Terminase
WT60_11760	COG5002	protein histidine kinase activity
WT60_11765	COG0745	RESPONSE REGULATOR receiver
WT60_11780	COG0581	inorganic phosphate transmembrane transporter activity
WT60_11785	COG0573	inorganic phosphate transmembrane transporter activity
WT60_11790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WT60_11800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WT60_11805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WT60_11815	COG1534	Rna-binding protein
WT60_11825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WT60_11830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WT60_11840	COG0505	Belongs to the CarA family
WT60_11860	COG0741	lytic transglycosylase activity
WT60_11860	COG1388	LysM domain
WT60_11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WT60_11870	COG2226	methyltransferase
WT60_11875	COG0328	RNA-DNA hybrid ribonuclease activity
WT60_11880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WT60_11890	COG1742	UPF0060 membrane protein
WT60_11915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WT60_11925	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
WT60_11945	COG3052	prosthetic group binding
WT60_11965	COG0583	DNA-binding transcription factor activity
WT60_11975	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT60_11985	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
WT60_12005	COG0071	Belongs to the small heat shock protein (HSP20) family
WT60_12015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT60_12025	COG3547	Transposase (IS116 IS110 IS902 family)
WT60_12035	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_12040	COG0583	DNA-binding transcription factor activity
WT60_12070	COG3706	GGDEF domain
WT60_12070	COG0745	RESPONSE REGULATOR receiver
WT60_12090	COG1609	Transcriptional regulator
WT60_12095	COG1840	ABC-type Fe3 transport system, periplasmic component
WT60_12115	COG1177	transmembrane transport
WT60_12120	COG3842	ATPase activity
WT60_12125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WT60_12140	COG2814	Major facilitator Superfamily
WT60_12145	COG0697	spore germination
WT60_12155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WT60_12160	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WT60_12205	COG2200	EAL domain
WT60_12215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WT60_12220	COG1074	ATP-dependent DNA helicase activity
WT60_12225	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WT60_12240	COG1840	ABC-type Fe3 transport system, periplasmic component
WT60_12250	COG3842	ATPase activity
WT60_12255	COG1522	sequence-specific DNA binding
WT60_12265	COG0668	transmembrane transport
WT60_12280	COG1959	2 iron, 2 sulfur cluster binding
WT60_12300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_12305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_12310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_12335	COG2863	cytochrome
WT60_12340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WT60_12355	COG2010	Cytochrome c
WT60_12360	COG2863	cytochrome
WT60_12375	COG0798	PFAM Bile acid sodium symporter
WT60_12380	COG1393	Belongs to the ArsC family
WT60_12390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WT60_12400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WT60_12415	COG0006	proline dipeptidase activity
WT60_12475	COG2866	Carboxypeptidase
WT60_12490	COG0436	Aminotransferase
WT60_12495	COG0625	glutathione transferase activity
WT60_12500	COG1024	Enoyl-CoA hydratase
WT60_12505	COG0588	phosphoglycerate mutase activity
WT60_12515	COG1960	acyl-CoA dehydrogenase activity
WT60_12530	COG2030	dehydratase
WT60_12530	COG1012	belongs to the aldehyde dehydrogenase family
WT60_12535	COG1960	acyl-CoA dehydrogenase activity
WT60_12540	COG1960	acyl-CoA dehydrogenase activity
WT60_12560	COG1007	ATP synthesis coupled electron transport
WT60_12595	COG1034	ATP synthesis coupled electron transport
WT60_12595	COG1034	ATP synthesis coupled electron transport
WT60_12605	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WT60_12640	COG0149	triose-phosphate isomerase activity
WT60_12660	COG0683	leucine binding
WT60_12670	COG0288	reversible hydration of carbon dioxide
WT60_12675	COG0659	secondary active sulfate transmembrane transporter activity
WT60_12685	COG1183	phosphatidylcholine synthase activity
WT60_12705	COG0028	Belongs to the TPP enzyme family
WT60_12735	COG0438	transferase activity, transferring glycosyl groups
WT60_12755	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_12760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WT60_12770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_12780	COG0154	amidase activity
WT60_12790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WT60_12810	COG2076	Multidrug Resistance protein
WT60_12820	COG0745	RESPONSE REGULATOR receiver
WT60_12835	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WT60_12840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WT60_12870	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_12885	COG0151	Belongs to the GarS family
WT60_12900	COG0799	negative regulation of ribosome biogenesis
WT60_12915	COG1530	ribonuclease E activity
WT60_12930	COG2233	PERMEase
WT60_12965	COG1595	DNA-templated transcription, initiation
WT60_12970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WT60_13000	COG0859	PFAM glycosyl transferase family 9
WT60_13005	COG0438	transferase activity, transferring glycosyl groups
WT60_13025	COG1132	(ABC) transporter
WT60_13040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WT60_13045	COG0513	Belongs to the DEAD box helicase family
WT60_13070	COG1674	ftsk spoiiie
WT60_13075	COG2706	6-phosphogluconolactonase activity
WT60_13080	COG3387	PFAM Glycoside hydrolase 15-related
WT60_13090	COG1309	transcriptional regulator
WT60_13095	COG2878	Part of a membrane complex involved in electron transport
WT60_13100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WT60_13140	COG3135	benzoate transporter
WT60_13165	COG4106	trans-aconitate 2-methyltransferase activity
WT60_13185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT60_13195	COG0697	spore germination
WT60_13200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT60_13235	COG0583	DNA-binding transcription factor activity
WT60_13255	COG0187	DNA topoisomerase II activity
WT60_13270	COG1773	rubredoxin
WT60_13295	COG0582	viral genome integration into host DNA
WT60_13345	COG4372	Transposase
WT60_13350	COG3436	PFAM IS66 Orf2 family protein
WT60_13415	COG1881	PFAM PEBP family protein
WT60_13420	COG2814	Major facilitator Superfamily
WT60_13435	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WT60_13455	COG1116	anion transmembrane transporter activity
WT60_13460	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT60_13475	COG0745	RESPONSE REGULATOR receiver
WT60_13485	COG1741	Belongs to the pirin family
WT60_13490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT60_13495	COG4215	(ABC) transporter
WT60_13500	COG4160	amino acid transport
WT60_13520	COG0347	Belongs to the P(II) protein family
WT60_13540	COG2827	Endonuclease containing a URI domain
WT60_13545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WT60_13560	COG2271	Major facilitator Superfamily
WT60_13585	COG2226	methyltransferase
WT60_13630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT60_13640	COG1982	Orn Lys Arg decarboxylase major
WT60_13655	COG0489	protein tyrosine kinase activity
WT60_13660	COG3047	cAMP biosynthetic process
WT60_13660	COG2885	chlorophyll binding
WT60_13675	COG2911	Protein conserved in bacteria
WT60_13680	COG0729	surface antigen
WT60_13690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WT60_13715	COG2259	Doxx family
WT60_13720	COG1492	cobalamin metabolic process
WT60_13730	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
WT60_13740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WT60_13750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WT60_13755	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WT60_13760	COG1120	ATPase activity
WT60_13770	COG4206	TonB-dependent receptor
WT60_13800	COG0583	DNA-binding transcription factor activity
WT60_13830	COG0795	lipopolysaccharide-transporting ATPase activity
WT60_13850	COG1648	precorrin-2 dehydrogenase activity
WT60_13850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WT60_13855	COG2895	sulfate adenylyltransferase (ATP) activity
WT60_13865	COG0175	sulfate reduction
WT60_13880	COG0583	DNA-binding transcription factor activity
WT60_13895	COG0582	viral genome integration into host DNA
WT60_13940	COG2267	carboxylic ester hydrolase activity
WT60_13950	COG0583	DNA-binding transcription factor activity
WT60_13960	COG1187	pseudouridine synthase activity
WT60_13975	COG0543	2 iron, 2 sulfur cluster binding
WT60_13975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WT60_13980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WT60_13985	COG0456	acetyltransferase
WT60_14020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WT60_14025	COG1047	Peptidyl-prolyl cis-trans
WT60_14040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WT60_14045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WT60_14065	COG3264	Mechanosensitive ion channel
WT60_14065	COG1511	domain protein
WT60_14070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WT60_14070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WT60_14075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WT60_14080	COG0196	riboflavin kinase activity
WT60_14095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WT60_14115	COG1113	amino acid transport
WT60_14120	COG0542	response to heat
WT60_14130	COG1278	Cold shock
WT60_14135	COG2132	Multicopper oxidase
WT60_14155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WT60_14170	COG0656	L-ascorbic acid biosynthetic process
WT60_14175	COG2188	Transcriptional regulator
WT60_14190	COG2814	Major facilitator Superfamily
WT60_14235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WT60_14245	COG1663	tetraacyldisaccharide 4'-kinase activity
WT60_14275	COG0728	peptidoglycan biosynthetic process
WT60_14290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WT60_14295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WT60_14310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WT60_14315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WT60_14320	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_14325	COG4974	Belongs to the 'phage' integrase family
WT60_14335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WT60_14340	COG0802	atpase or kinase
WT60_14345	COG0860	N-Acetylmuramoyl-L-alanine amidase
WT60_14360	COG1741	Belongs to the pirin family
WT60_14370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WT60_14380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WT60_14390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WT60_14395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WT60_14400	COG1522	sequence-specific DNA binding
WT60_14435	COG1012	belongs to the aldehyde dehydrogenase family
WT60_14450	COG0246	Mannitol dehydrogenase
WT60_14455	COG1070	Carbohydrate kinase
WT60_14490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT60_14500	COG4209	transmembrane transport
WT60_14515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT60_14525	COG0735	belongs to the Fur family
WT60_14535	COG1121	(ABC) transporter
WT60_14545	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WT60_14560	COG1070	Carbohydrate kinase
WT60_14565	COG2233	PERMEase
WT60_14580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_14585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_14610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT60_14620	COG0745	RESPONSE REGULATOR receiver
WT60_14640	COG0009	L-threonylcarbamoyladenylate synthase
WT60_14645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WT60_14650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WT60_14655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WT60_14665	COG0469	pyruvate kinase activity
WT60_14670	COG0126	phosphoglycerate kinase activity
WT60_14695	COG0859	PFAM glycosyl transferase family 9
WT60_14705	COG0429	hydrolase of the alpha beta-hydrolase fold
WT60_14720	COG4783	chaperone-mediated protein folding
WT60_14745	COG3307	-O-antigen
WT60_14750	COG4969	Belongs to the N-Me-Phe pilin family
WT60_14755	COG0861	Integral membrane protein TerC family
WT60_14760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WT60_14775	COG2137	regulation of response to DNA damage stimulus
WT60_14780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WT60_14790	COG0642	Histidine kinase
WT60_14810	COG3436	PFAM IS66 Orf2 family protein
WT60_14815	COG4372	Transposase
WT60_14830	COG0583	DNA-binding transcription factor activity
WT60_14845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
WT60_14860	COG0287	Prephenate dehydrogenase
WT60_14880	COG0439	Biotin carboxylase
WT60_14910	COG2814	Major facilitator Superfamily
WT60_14940	COG2205	protein histidine kinase activity
WT60_14940	COG0784	Response regulator, receiver
WT60_14945	COG0583	DNA-binding transcription factor activity
WT60_15005	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WT60_15030	COG0679	Auxin Efflux Carrier
WT60_15035	COG0840	transmembrane signaling receptor activity
WT60_15070	COG4948	Mandelate Racemase Muconate Lactonizing
WT60_15090	COG0513	Belongs to the DEAD box helicase family
WT60_15130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WT60_15135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WT60_15145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT60_15150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WT60_15160	COG2814	Major facilitator Superfamily
WT60_15165	COG0583	DNA-binding transcription factor activity
WT60_15175	COG1702	phosphate starvation-inducible protein PhoH
WT60_15185	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
WT60_15195	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WT60_15210	COG0751	glycine-tRNA ligase activity
WT60_15215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WT60_15220	COG0204	Acyl-transferase
WT60_15255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WT60_15265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WT60_15275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WT60_15280	COG5265	(ABC) transporter
WT60_15285	COG1607	acyl-coa hydrolase
WT60_15295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WT60_15300	COG1024	Enoyl-CoA hydratase
WT60_15305	COG0183	Belongs to the thiolase family
WT60_15310	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT60_15310	COG1024	Enoyl-CoA hydratase
WT60_15315	COG1960	acyl-CoA dehydrogenase activity
WT60_15330	COG0494	nUDIX hydrolase
WT60_15390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WT60_15400	COG0251	oxidation-reduction process
WT60_15405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WT60_15430	COG0477	Major facilitator Superfamily
WT60_15465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WT60_15480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WT60_15490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WT60_15510	COG2204	response regulator
WT60_15545	COG5001	Diguanylate cyclase
WT60_15545	COG5002	protein histidine kinase activity
WT60_15550	COG0235	Class ii aldolase
WT60_15690	COG0629	single-stranded DNA binding
WT60_15695	COG2814	Major facilitator Superfamily
WT60_15720	COG1280	lysine exporter protein (LysE YggA)
WT60_15740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WT60_15755	COG1137	ATPase activity
WT60_15760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WT60_15765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WT60_15790	COG1194	a g-specific adenine glycosylase
WT60_15805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WT60_15820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WT60_15840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WT60_15850	COG0742	ribosomal rna small subunit methyltransferase
WT60_15860	COG0625	glutathione transferase activity
WT60_15870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WT60_15880	COG0243	molybdopterin cofactor binding
WT60_15885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WT60_15890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WT60_15900	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WT60_15905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WT60_15920	COG1294	oxidase, subunit
WT60_15935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WT60_15935	COG1263	PTS System
WT60_15935	COG2190	(PTS) system
WT60_15940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WT60_15940	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WT60_15945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WT60_15950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WT60_15955	COG2188	Transcriptional regulator
WT60_15960	COG0583	DNA-binding transcription factor activity
WT60_16005	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_16015	COG1960	acyl-CoA dehydrogenase activity
WT60_16025	COG2226	methyltransferase
WT60_16035	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WT60_16070	COG0587	DNA-directed DNA polymerase activity
WT60_16085	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WT60_16105	COG0840	transmembrane signaling receptor activity
WT60_16115	COG1999	signal sequence binding
WT60_16125	COG1612	heme a metabolic process
WT60_16160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WT60_16175	COG2226	methyltransferase
WT60_16180	COG1040	competence protein
WT60_16190	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WT60_16210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WT60_16220	COG0793	Belongs to the peptidase S41A family
WT60_16225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WT60_16230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WT60_16235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WT60_16245	COG0189	ligase activity
WT60_16255	COG0004	ammonium transporteR
WT60_16265	COG2960	long-chain fatty acid transporting porin activity
WT60_16270	COG0606	chelatase, subunit chli
WT60_16290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WT60_16300	COG4191	Histidine kinase
WT60_16310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT60_16315	COG1960	acyl-CoA dehydrogenase activity
WT60_16320	COG1960	acyl-CoA dehydrogenase activity
WT60_16325	COG1024	Enoyl-CoA hydratase
WT60_16325	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT60_16330	COG0583	DNA-binding transcription factor activity
WT60_16365	COG0583	DNA-binding transcription factor activity
WT60_16370	COG2921	Belongs to the UPF0250 family
WT60_16380	COG1686	Belongs to the peptidase S11 family
WT60_16415	COG1127	ABC transporter
WT60_16420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WT60_16425	COG0737	Belongs to the 5'-nucleotidase family
WT60_16465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WT60_16485	COG1024	Enoyl-CoA hydratase
WT60_16535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WT60_16540	COG0300	oxidoreductase activity
WT60_16545	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_16555	COG0183	Belongs to the thiolase family
WT60_16560	COG0747	negative chemotaxis
WT60_16580	COG0288	reversible hydration of carbon dioxide
WT60_16585	COG0183	Belongs to the thiolase family
WT60_16590	COG0300	oxidoreductase activity
WT60_16595	COG3012	SEC-C Motif Domain Protein
WT60_16625	COG3142	Participates in the control of copper homeostasis
WT60_16645	COG2199	diguanylate cyclase activity
WT60_16645	COG2200	EAL domain
WT60_16650	COG0025	NhaP-type Na H and K H
WT60_16675	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WT60_16685	COG0463	Glycosyl transferase, family 2
WT60_16735	COG4964	Belongs to the GSP D family
WT60_16780	COG1335	isochorismatase
WT60_16815	COG0583	DNA-binding transcription factor activity
WT60_16825	COG1335	isochorismatase
WT60_16835	COG1335	isochorismatase
WT60_16850	COG0583	DNA-binding transcription factor activity
WT60_16865	COG0583	DNA-binding transcription factor activity
WT60_16870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
WT60_16885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WT60_16890	COG0596	Alpha beta hydrolase
WT60_16915	COG3511	phospholipase C
WT60_16930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WT60_16960	COG0596	Alpha beta hydrolase
WT60_16970	COG0583	DNA-binding transcription factor activity
WT60_16975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_16990	COG0840	transmembrane signaling receptor activity
WT60_16995	COG1609	Transcriptional regulator
WT60_17050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WT60_17065	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_17070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_17090	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WT60_17095	COG1704	LemA family
WT60_17105	COG2217	Heavy metal translocating P-type atpase
WT60_17210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_17225	COG2824	Alkylphosphonate utilization operon protein PhnA
WT60_17245	COG0583	DNA-binding transcription factor activity
WT60_17250	COG2233	PERMEase
WT60_17255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WT60_17260	COG1256	bacterial-type flagellum assembly
WT60_17265	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WT60_17275	COG1706	bacterial-type flagellum-dependent cell motility
WT60_17280	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WT60_17285	COG4786	Flagellar basal body rod
WT60_17295	COG1749	Flagellar hook protein flgE
WT60_17300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WT60_17305	COG1558	bacterial-type flagellum-dependent cell motility
WT60_17320	COG2747	anti-sigma28 factor FlgM
WT60_17420	COG0741	lytic transglycosylase activity
WT60_17425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WT60_17435	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WT60_17440	COG1984	allophanate hydrolase subunit 2
WT60_17445	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
WT60_17465	COG4608	Belongs to the ABC transporter superfamily
WT60_17470	COG0444	Belongs to the ABC transporter superfamily
WT60_17475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WT60_17480	COG0601	transmembrane transport
WT60_17485	COG0747	negative chemotaxis
WT60_17490	COG0477	Major facilitator Superfamily
WT60_17500	COG0579	oxidoreductase
WT60_17515	COG3568	Endonuclease Exonuclease Phosphatase
WT60_17520	COG1280	lysine exporter protein (LysE YggA)
WT60_17540	COG0531	amino acid
WT60_17555	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT60_17585	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WT60_17595	COG1157	protein secretion by the type III secretion system
WT60_17615	COG1960	acyl-CoA dehydrogenase activity
WT60_17630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT60_17645	COG4948	Mandelate Racemase Muconate Lactonizing
WT60_17650	COG2271	Major facilitator Superfamily
WT60_17660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WT60_17665	COG0583	DNA-binding transcription factor activity
WT60_17670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WT60_17680	COG2814	Major facilitator Superfamily
WT60_17695	COG0667	Aldo Keto reductase
WT60_17720	COG1560	Kdo2-lipid A biosynthetic process
WT60_17735	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WT60_17740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WT60_17745	COG0523	cobalamin synthesis protein
WT60_17750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WT60_17755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WT60_17760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WT60_17765	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WT60_17790	COG1309	transcriptional regulator
WT60_17805	COG2814	Major facilitator Superfamily
WT60_17815	COG2207	Transcriptional regulator
WT60_17820	COG1064	alcohol dehydrogenase
WT60_17825	COG0708	Exodeoxyribonuclease III
WT60_17830	COG2326	polyphosphate kinase activity
WT60_17845	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WT60_17850	COG1077	Cell shape determining protein MreB Mrl
WT60_17865	COG0768	penicillin binding
WT60_17870	COG0772	Belongs to the SEDS family
WT60_17885	COG0720	synthase
WT60_17890	COG0602	queuosine metabolic process
WT60_17905	COG2204	response regulator
WT60_17910	COG5000	phosphorelay sensor kinase activity
WT60_17940	COG0242	peptide deformylase activity
WT60_17945	COG0758	DNA mediated transformation
WT60_17960	COG0583	DNA-binding transcription factor activity
WT60_17965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT60_17985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WT60_18000	COG0583	DNA-binding transcription factor activity
WT60_18010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WT60_18030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WT60_18030	COG2169	Transcriptional regulator
WT60_18040	COG4681	YaeQ
WT60_18050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WT60_18080	COG0582	viral genome integration into host DNA
WT60_18135	COG1396	sequence-specific DNA binding
WT60_18150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WT60_18170	COG1309	transcriptional regulator
WT60_18185	COG1012	belongs to the aldehyde dehydrogenase family
WT60_18190	COG0473	3-isopropylmalate dehydrogenase activity
WT60_18195	COG0583	DNA-binding transcription factor activity
WT60_18205	COG0625	glutathione transferase activity
WT60_18215	COG1522	sequence-specific DNA binding
WT60_18225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WT60_18245	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_18255	COG0671	phosphoesterase, PA-phosphatase related
WT60_18300	COG3121	Chaperone
WT60_18335	COG2197	response regulator
WT60_18340	COG0784	Response regulator, receiver
WT60_18340	COG2205	protein histidine kinase activity
WT60_18365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT60_18365	COG2205	protein histidine kinase activity
WT60_18405	COG3539	Fimbrial protein
WT60_18410	COG3121	Chaperone
WT60_18450	COG0686	Belongs to the AlaDH PNT family
WT60_18465	COG1024	Enoyl-CoA hydratase
WT60_18475	COG0477	Major facilitator Superfamily
WT60_18510	COG1279	arginine transmembrane transporter activity
WT60_18520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WT60_18525	COG0589	response to stress
WT60_18560	COG1045	serine acetyltransferase
WT60_18565	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_18570	COG0302	gtp cyclohydrolase
WT60_18590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WT60_18600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WT60_18605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WT60_18640	COG0432	Pfam Uncharacterised protein family UPF0047
WT60_18660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WT60_18670	COG5295	Hep Hag repeat protein
WT60_18690	COG3121	Chaperone
WT60_18695	COG3188	usher protein
WT60_18700	COG3539	Fimbrial protein
WT60_18710	COG2885	chlorophyll binding
WT60_18755	COG3501	Rhs element vgr protein
WT60_18815	COG0784	Response regulator, receiver
WT60_18815	COG2205	protein histidine kinase activity
WT60_18850	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT60_18855	COG2271	Major facilitator Superfamily
WT60_18860	COG1929	Belongs to the glycerate kinase type-1 family
WT60_18865	COG0469	pyruvate kinase activity
WT60_18870	COG3835	regulator
WT60_18875	COG0300	oxidoreductase activity
WT60_18875	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_18875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT60_18875	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_18875	COG3321	synthase
WT60_18905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WT60_18915	COG3454	Phosphonate metabolism
WT60_18920	COG4778	phosphonate C-P lyase system protein PhnL
WT60_18925	COG4107	phosphonate C-P lyase system protein PhnK
WT60_18930	COG3627	carbon phosphorus lyase activity
WT60_18935	COG3626	phosphonate metabolism
WT60_18940	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
WT60_18945	COG3624	Phosphonate C-P lyase system protein PhnG
WT60_18950	COG2188	Transcriptional regulator
WT60_18960	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
WT60_18965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
WT60_18970	COG0110	maltose O-acetyltransferase activity
WT60_18975	COG2203	Gaf domain
WT60_18975	COG3706	GGDEF domain
WT60_18975	COG4251	negative regulation of phosphorylation
WT60_18975	COG5001	Diguanylate cyclase
WT60_18985	COG1879	ABC-type sugar transport system periplasmic component
WT60_18990	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_19020	COG0477	Major facilitator Superfamily
WT60_19025	COG1473	amidohydrolase
WT60_19030	COG0583	DNA-binding transcription factor activity
WT60_19080	COG3537	Alpha-1,2-mannosidase
WT60_19100	COG0367	asparagine synthase
WT60_19165	COG1304	FMN binding
WT60_19170	COG0583	DNA-binding transcription factor activity
WT60_19175	COG0477	Major facilitator Superfamily
WT60_19190	COG2423	ornithine cyclodeaminase activity
WT60_19195	COG1522	sequence-specific DNA binding
WT60_19200	COG0583	DNA-binding transcription factor activity
WT60_19315	COG3501	Rhs element vgr protein
WT60_19365	COG0406	alpha-ribazole phosphatase activity
WT60_19370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WT60_19375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT60_19385	COG4221	oxidoreductase activity
WT60_19420	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_19450	COG3708	Transcriptional regulator
WT60_19450	COG2207	Transcriptional regulator
WT60_19455	COG1335	isochorismatase
WT60_19465	COG1022	Amp-dependent synthetase and ligase
WT60_19475	COG3246	L-lysine catabolic process to acetate
WT60_19490	COG1960	acyl-CoA dehydrogenase activity
WT60_19495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WT60_19500	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_19505	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_19510	COG1960	acyl-CoA dehydrogenase activity
WT60_19540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WT60_19565	COG1253	flavin adenine dinucleotide binding
WT60_19570	COG0583	DNA-binding transcription factor activity
WT60_19595	COG1215	transferase activity, transferring glycosyl groups
WT60_19625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WT60_19650	COG0672	)-iron permease
WT60_19685	COG1404	Belongs to the peptidase S8 family
WT60_19695	COG1573	uracil-dna glycosylase
WT60_19745	COG1230	cation diffusion facilitator family transporter
WT60_19765	COG3206	protein involved in exopolysaccharide biosynthesis
WT60_19765	COG0489	protein tyrosine kinase activity
WT60_19805	COG0745	RESPONSE REGULATOR receiver
WT60_19805	COG3706	GGDEF domain
WT60_19815	COG0596	Alpha beta hydrolase
WT60_19845	COG0625	glutathione transferase activity
WT60_19855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WT60_19860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
WT60_19885	COG2823	Periplasmic or secreted lipoprotein
WT60_19895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WT60_19900	COG0280	phosphate acetyltransferase
WT60_19905	COG3243	poly(R)-hydroxyalkanoic acid synthase
WT60_19915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WT60_19930	COG0356	it plays a direct role in the translocation of protons across the membrane
WT60_19940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WT60_19940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WT60_19980	COG1252	NADH dehydrogenase
WT60_19990	COG0842	Transport permease protein
WT60_19995	COG1129	ABC transporter
WT60_19995	COG0842	Transport permease protein
WT60_20000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_20015	COG0589	response to stress
WT60_20030	COG1136	(ABC) transporter
WT60_20065	COG1611	Belongs to the LOG family
WT60_20100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WT60_20105	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_20110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WT60_20125	COG0833	amino acid
WT60_20135	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_20140	COG0543	2 iron, 2 sulfur cluster binding
WT60_20140	COG0633	Ferredoxin
WT60_20145	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
WT60_20150	COG4638	Rieske (2fe-2S)
WT60_20155	COG0583	DNA-binding transcription factor activity
WT60_20170	COG0640	Transcriptional regulator
WT60_20190	COG1902	pentaerythritol trinitrate reductase activity
WT60_20190	COG0446	pyridine nucleotide-disulphide oxidoreductase
WT60_20215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WT60_20220	COG0745	RESPONSE REGULATOR receiver
WT60_20230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_20235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_20270	COG4638	Rieske (2fe-2S)
WT60_20275	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
WT60_20280	COG2146	nitrite reductase [NAD(P)H] activity
WT60_20295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WT60_20305	COG2733	membrane
WT60_20315	COG0025	NhaP-type Na H and K H
WT60_20325	COG1012	belongs to the aldehyde dehydrogenase family
WT60_20335	COG0642	Histidine kinase
WT60_20340	COG0840	transmembrane signaling receptor activity
WT60_20365	COG2201	protein-glutamate methylesterase activity
WT60_20375	COG0038	chloride channel
WT60_20400	COG4977	sequence-specific DNA binding
WT60_20410	COG5265	(ABC) transporter
WT60_20415	COG2837	iron assimilation
WT60_20455	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_20470	COG2130	NADP-dependent
WT60_20490	COG4771	TonB-dependent receptor
WT60_20500	COG0628	permease
WT60_20525	COG3795	YCII-related domain
WT60_20540	COG4941	Belongs to the sigma-70 factor family
WT60_20545	COG3023	N-Acetylmuramoyl-L-alanine amidase
WT60_20550	COG1592	Rubrerythrin
WT60_20555	COG0247	lactate metabolic process
WT60_20595	COG0489	protein tyrosine kinase activity
WT60_20595	COG3206	protein involved in exopolysaccharide biosynthesis
WT60_20615	COG0438	transferase activity, transferring glycosyl groups
WT60_20620	COG0438	transferase activity, transferring glycosyl groups
WT60_20645	COG5642	Protein of unknown function (DUF2384)
WT60_20650	COG5654	RES domain protein
WT60_20655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WT60_20680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT60_20700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WT60_20705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WT60_20755	COG1304	FMN binding
WT60_20770	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WT60_20775	COG0352	thiamine-phosphate diphosphorylase activity
WT60_20780	COG1253	flavin adenine dinucleotide binding
WT60_20795	COG0583	DNA-binding transcription factor activity
WT60_20820	COG4149	molybdate abc transporter
WT60_20825	COG0725	ABC transporter, periplasmic molybdate-binding protein
WT60_20840	COG1764	response to oxidative stress
WT60_20845	COG1846	Transcriptional regulator
WT60_20870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WT60_20880	COG1611	Belongs to the LOG family
WT60_20890	COG1252	NADH dehydrogenase
WT60_20910	COG0412	Dienelactone hydrolase
WT60_20930	COG0142	geranyltranstransferase activity
WT60_20955	COG2081	HI0933 family
WT60_20980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WT60_21190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT60_21195	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WT60_21235	COG3038	cytochrome b561
WT60_21245	COG4771	TonB-dependent receptor
WT60_21265	COG3842	ATPase activity
WT60_21275	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT60_21280	COG1177	transmembrane transport
WT60_21325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WT60_21345	COG0039	L-malate dehydrogenase activity
WT60_21350	COG2188	Transcriptional regulator
WT60_21355	COG2009	succinate dehydrogenase
WT60_21365	COG1053	succinate dehydrogenase
WT60_21370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WT60_21375	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WT60_21380	COG0372	Belongs to the citrate synthase family
WT60_21410	COG1522	sequence-specific DNA binding
WT60_21430	COG0473	3-isopropylmalate dehydrogenase activity
WT60_21455	COG0135	phosphoribosylanthranilate isomerase activity
WT60_21460	COG0133	tryptophan synthase activity
WT60_21475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WT60_21480	COG0285	dihydrofolate synthase activity
WT60_21510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT60_21515	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
WT60_21520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT60_21520	COG2755	lipolytic protein G-D-S-L family
WT60_21545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WT60_21550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT60_21550	COG2755	lipolytic protein G-D-S-L family
WT60_21560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_21565	COG1295	ribonuclease BN
WT60_21580	COG3608	succinylglutamate desuccinylase aspartoacylase
WT60_21595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WT60_21605	COG2204	response regulator
WT60_21675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WT60_21680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WT60_21690	COG1126	abc transporter atp-binding protein
WT60_21715	COG3383	formate dehydrogenase (NAD+) activity
WT60_21715	COG0243	molybdopterin cofactor binding
WT60_21720	COG3383	formate dehydrogenase (NAD+) activity
WT60_21720	COG0243	molybdopterin cofactor binding
WT60_21725	COG0437	4 iron, 4 sulfur cluster binding
WT60_21730	COG2864	formate dehydrogenase
WT60_21745	COG3276	selenocysteine insertion sequence binding
WT60_21810	COG0583	DNA-binding transcription factor activity
WT60_21825	COG0427	acetyl-CoA hydrolase
WT60_21840	COG0303	'Molybdopterin
WT60_21895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT60_21900	COG4789	Type iii secretion
WT60_21920	COG4794	Type iii secretion
WT60_21950	COG2207	Transcriptional regulator
WT60_22075	COG3550	peptidyl-serine autophosphorylation
WT60_22090	COG2175	clavaminate synthase activity
WT60_22095	COG4521	taurine ABC transporter
WT60_22100	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WT60_22105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT60_22130	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_22140	COG0306	phosphate transporter
WT60_22150	COG1522	sequence-specific DNA binding
WT60_22155	COG1280	lysine exporter protein (LysE YggA)
WT60_22180	COG0583	DNA-binding transcription factor activity
WT60_22185	COG1741	Belongs to the pirin family
WT60_22215	COG1335	isochorismatase
WT60_22230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WT60_22260	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WT60_22260	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WT60_22290	COG5564	TIM-barrel signal transduction protein
WT60_22295	COG5441	Belongs to the UPF0261 family
WT60_22325	COG1063	alcohol dehydrogenase
WT60_22330	COG4948	Mandelate Racemase Muconate Lactonizing
WT60_22340	COG0246	Mannitol dehydrogenase
WT60_22345	COG2271	Major facilitator Superfamily
WT60_22350	COG1349	DNA-binding transcription factor activity
WT60_22365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT60_22375	COG0583	DNA-binding transcription factor activity
WT60_22385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT60_22390	COG1012	belongs to the aldehyde dehydrogenase family
WT60_22395	COG1477	protein flavinylation
WT60_22400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WT60_22420	COG0745	RESPONSE REGULATOR receiver
WT60_22425	COG0642	Histidine kinase
WT60_22450	COG2271	Major facilitator Superfamily
WT60_22480	COG1960	acyl-CoA dehydrogenase activity
WT60_22485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WT60_22520	COG5295	Hep Hag repeat protein
WT60_22635	COG3547	Transposase (IS116 IS110 IS902 family)
WT60_22640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT60_22645	COG3622	Belongs to the hyi family
WT60_22650	COG2271	Major facilitator Superfamily
WT60_22655	COG0235	Class ii aldolase
WT60_22660	COG3395	kinase activity
WT60_22665	COG2084	Dehydrogenase
WT60_22670	COG2186	Transcriptional regulator
WT60_22685	COG1309	transcriptional regulator
WT60_22690	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_22695	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_22735	COG1760	l-serine dehydratase
WT60_22750	COG0446	pyridine nucleotide-disulphide oxidoreductase
WT60_22750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WT60_22785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT60_22800	COG4251	negative regulation of phosphorylation
WT60_22805	COG0784	Response regulator, receiver
WT60_22815	COG0477	Major facilitator Superfamily
WT60_22850	COG2814	Major facilitator Superfamily
WT60_22875	COG1505	serine-type exopeptidase activity
WT60_22885	COG1045	serine acetyltransferase
WT60_22895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WT60_22900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WT60_22905	COG3038	cytochrome b561
WT60_22910	COG0640	Transcriptional regulator
WT60_22915	COG2391	methyltransferase activity
WT60_22950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
WT60_22955	COG1858	cytochrome C peroxidase
WT60_22980	COG2188	Transcriptional regulator
WT60_22995	COG3177	Filamentation induced by cAMP protein fic
WT60_23000	COG0546	phosphoglycolate phosphatase activity
WT60_23040	COG4608	Belongs to the ABC transporter superfamily
WT60_23045	COG0444	Belongs to the ABC transporter superfamily
WT60_23055	COG0601	transmembrane transport
WT60_23060	COG0747	negative chemotaxis
WT60_23065	COG0583	DNA-binding transcription factor activity
WT60_23095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WT60_23105	COG1446	asparaginase
WT60_23110	COG4172	Belongs to the ABC transporter superfamily
WT60_23120	COG0601	transmembrane transport
WT60_23125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WT60_23150	COG3485	protocatechuate 3,4-dioxygenase
WT60_23155	COG3485	protocatechuate 3,4-dioxygenase
WT60_23160	COG0583	DNA-binding transcription factor activity
WT60_23180	COG5001	Diguanylate cyclase
WT60_23180	COG2203	Gaf domain
WT60_23180	COG3706	GGDEF domain
WT60_23180	COG4251	negative regulation of phosphorylation
WT60_23200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WT60_23205	COG3795	YCII-related domain
WT60_23220	COG1201	RNA secondary structure unwinding
WT60_23285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WT60_23305	COG1914	H( )-stimulated, divalent metal cation uptake system
WT60_23315	COG1739	Uncharacterized protein family UPF0029
WT60_23350	COG0667	Aldo Keto reductase
WT60_23355	COG0477	Major facilitator Superfamily
WT60_23365	COG0583	DNA-binding transcription factor activity
WT60_23380	COG1979	alcohol dehydrogenase
WT60_23385	COG2130	NADP-dependent
WT60_23420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT60_23430	COG0583	DNA-binding transcription factor activity
WT60_23455	COG0583	DNA-binding transcription factor activity
WT60_23460	COG0477	Major facilitator Superfamily
WT60_23480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WT60_23480	COG1116	anion transmembrane transporter activity
WT60_23490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WT60_23495	COG2146	nitrite reductase [NAD(P)H] activity
WT60_23500	COG0243	molybdopterin cofactor binding
WT60_23520	COG1686	Belongs to the peptidase S11 family
WT60_23530	COG0741	lytic transglycosylase activity
WT60_23585	COG2205	protein histidine kinase activity
WT60_23585	COG3437	response regulator, receiver
WT60_23585	COG3850	Histidine kinase
WT60_23585	COG4999	Histidine kinase
WT60_23590	COG2197	response regulator
WT60_23710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT60_23760	COG2223	nitrite transmembrane transporter activity
WT60_23765	COG1349	DNA-binding transcription factor activity
WT60_23790	COG1902	pentaerythritol trinitrate reductase activity
WT60_23830	COG4651	solute:proton antiporter activity
WT60_23830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WT60_23835	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_23850	COG0840	transmembrane signaling receptor activity
WT60_23860	COG1335	isochorismatase
WT60_23875	COG4774	siderophore transport
WT60_23880	COG0540	Belongs to the ATCase OTCase family
WT60_23890	COG1414	Transcriptional regulator
WT60_23895	COG0477	Major facilitator Superfamily
WT60_23920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WT60_23935	COG3851	Histidine kinase
WT60_23945	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WT60_23950	COG1140	nitrate reductase beta subunit
WT60_23955	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WT60_23960	COG2181	nitrate reductase activity
WT60_23965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WT60_24005	COG0651	ATP synthesis coupled electron transport
WT60_24010	COG0650	Formate hydrogenlyase subunit 4
WT60_24020	COG0651	ATP synthesis coupled electron transport
WT60_24025	COG0649	NAD binding
WT60_24030	COG3260	NADH ubiquinone oxidoreductase 20
WT60_24070	COG1695	Transcriptional regulator
WT60_24075	COG1902	pentaerythritol trinitrate reductase activity
WT60_24075	COG0446	pyridine nucleotide-disulphide oxidoreductase
WT60_24110	COG2345	Transcriptional regulator
WT60_24115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WT60_24115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WT60_24120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WT60_24135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WT60_24140	COG1538	Outer membrane efflux protein
WT60_24145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_24150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_24230	COG2264	protein methyltransferase activity
WT60_24265	COG4274	PFAM GYD family protein
WT60_24280	COG0443	Heat shock 70 kDa protein
WT60_24445	COG4695	Portal protein
WT60_24450	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WT60_24455	COG3657	addiction module killer protein
WT60_24480	COG1192	Involved in chromosome partitioning
WT60_24560	COG0583	DNA-binding transcription factor activity
WT60_24575	COG0667	Aldo Keto reductase
WT60_24580	COG2963	transposase activity
WT60_24600	COG0492	ferredoxin-NADP+ reductase activity
WT60_24615	COG1960	acyl-CoA dehydrogenase activity
WT60_24675	COG3436	PFAM IS66 Orf2 family protein
WT60_24680	COG4372	Transposase
WT60_24685	COG2963	transposase activity
WT60_24690	COG2801	Transposase and inactivated derivatives
WT60_24705	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT60_24710	COG1177	transmembrane transport
WT60_24720	COG4372	Transposase
WT60_24725	COG3436	PFAM IS66 Orf2 family protein
WT60_24750	COG4149	molybdate abc transporter
WT60_24755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WT60_24835	COG2814	Major facilitator Superfamily
WT60_24860	COG1129	ABC transporter
WT60_24865	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_24870	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_24885	COG3712	iron ion homeostasis
WT60_24890	COG1595	DNA-templated transcription, initiation
WT60_24920	COG0179	Fumarylacetoacetate (FAA) hydrolase
WT60_24945	COG0387	Pfam Sodium calcium exchanger
WT60_24955	COG0583	DNA-binding transcription factor activity
WT60_24985	COG3275	phosphorelay sensor kinase activity
WT60_25030	COG4160	amino acid transport
WT60_25035	COG4215	(ABC) transporter
WT60_25045	COG2259	Doxx family
WT60_25070	COG1404	Belongs to the peptidase S8 family
WT60_25090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT60_25095	COG0243	molybdopterin cofactor binding
WT60_25100	COG3781	membrane
WT60_25110	COG1914	H( )-stimulated, divalent metal cation uptake system
WT60_25115	COG2140	Oxalate decarboxylase
WT60_25120	COG4166	transmembrane transport
WT60_25145	COG0747	negative chemotaxis
WT60_25150	COG0601	transmembrane transport
WT60_25155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WT60_25165	COG4172	Belongs to the ABC transporter superfamily
WT60_25180	COG0583	DNA-binding transcription factor activity
WT60_25205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_25220	COG2423	ornithine cyclodeaminase activity
WT60_25235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WT60_25260	COG0840	transmembrane signaling receptor activity
WT60_25285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WT60_25310	COG0596	Alpha beta hydrolase
WT60_25340	COG1522	sequence-specific DNA binding
WT60_25345	COG0154	amidase activity
WT60_25365	COG0477	Major facilitator Superfamily
WT60_25380	COG1012	belongs to the aldehyde dehydrogenase family
WT60_25390	COG0028	Belongs to the TPP enzyme family
WT60_25395	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_25400	COG1414	Transcriptional regulator
WT60_25430	COG2146	nitrite reductase [NAD(P)H] activity
WT60_25435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_25440	COG1414	Transcriptional regulator
WT60_25455	COG1408	metallophosphoesterase
WT60_25460	COG1285	pathogenesis
WT60_25465	COG2197	response regulator
WT60_25485	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WT60_25490	COG0516	GMP reductase activity
WT60_25490	COG0517	IMP dehydrogenase activity
WT60_25505	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_25520	COG1902	pentaerythritol trinitrate reductase activity
WT60_25540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_25555	COG0531	amino acid
WT60_25565	COG1012	belongs to the aldehyde dehydrogenase family
WT60_25600	COG0583	DNA-binding transcription factor activity
WT60_25620	COG0583	DNA-binding transcription factor activity
WT60_25640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT60_25645	COG1957	nucleoside hydrolase
WT60_25685	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT60_25695	COG1113	amino acid transport
WT60_25710	COG4221	oxidoreductase activity
WT60_25740	COG0589	response to stress
WT60_25795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WT60_25815	COG3291	Pkd domain containing protein
WT60_25820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT60_25840	COG2201	protein-glutamate methylesterase activity
WT60_25905	COG1448	Aminotransferase
WT60_25915	COG1522	sequence-specific DNA binding
WT60_25935	COG0438	transferase activity, transferring glycosyl groups
WT60_25950	COG1272	protein, Hemolysin III
WT60_25960	COG0683	leucine binding
WT60_26000	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_26005	COG1012	belongs to the aldehyde dehydrogenase family
WT60_26010	COG1024	Enoyl-CoA hydratase
WT60_26045	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_26105	COG3436	PFAM IS66 Orf2 family protein
WT60_26110	COG4372	Transposase
WT60_26130	COG2271	Major facilitator Superfamily
WT60_26135	COG2721	sulfolactate sulfo-lyase activity
WT60_26140	COG1609	Transcriptional regulator
WT60_26160	COG1858	cytochrome C peroxidase
WT60_26165	COG0038	chloride channel
WT60_26190	COG0402	S-adenosylhomocysteine deaminase activity
WT60_26195	COG2508	Transcriptional regulator
WT60_26200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WT60_26215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_26225	COG0583	DNA-binding transcription factor activity
WT60_26255	COG2197	response regulator
WT60_26300	COG0840	transmembrane signaling receptor activity
WT60_26310	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_26335	COG1278	Cold shock
WT60_26360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_26375	COG0642	Histidine kinase
WT60_26410	COG0454	-acetyltransferase
WT60_26415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WT60_26420	COG1902	pentaerythritol trinitrate reductase activity
WT60_26435	COG1309	transcriptional regulator
WT60_26445	COG2814	Major facilitator Superfamily
WT60_26450	COG1335	isochorismatase
WT60_26480	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WT60_26485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WT60_26505	COG1024	Enoyl-CoA hydratase
WT60_26520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_26540	COG0583	DNA-binding transcription factor activity
WT60_26545	COG1960	acyl-CoA dehydrogenase activity
WT60_26550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WT60_26570	COG1116	anion transmembrane transporter activity
WT60_26585	COG0633	Ferredoxin
WT60_26585	COG3217	Mosc domain protein beta barrel domain protein
WT60_26590	COG0642	Histidine kinase
WT60_26600	COG1840	ABC-type Fe3 transport system, periplasmic component
WT60_26610	COG3842	ATPase activity
WT60_26615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_26630	COG2207	Transcriptional regulator
WT60_26640	COG3971	2-oxopent-4-enoate hydratase activity
WT60_26650	COG3384	dioxygenase
WT60_26655	COG1012	belongs to the aldehyde dehydrogenase family
WT60_26670	COG1846	Transcriptional regulator
WT60_26685	COG0745	RESPONSE REGULATOR receiver
WT60_26690	COG2205	protein histidine kinase activity
WT60_26730	COG2207	Transcriptional regulator
WT60_26745	COG0745	RESPONSE REGULATOR receiver
WT60_26765	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
WT60_26775	COG0477	Major facilitator Superfamily
WT60_26780	COG3214	Protein conserved in bacteria
WT60_26830	COG4977	sequence-specific DNA binding
WT60_26835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WT60_26855	COG0745	RESPONSE REGULATOR receiver
WT60_26890	COG1649	PFAM Uncharacterised BCR, COG1649
WT60_26920	COG1077	Cell shape determining protein MreB Mrl
WT60_26930	COG2205	protein histidine kinase activity
WT60_26935	COG0745	RESPONSE REGULATOR receiver
WT60_26940	COG2066	Belongs to the glutaminase family
WT60_26965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_26975	COG1538	Outer membrane efflux protein
WT60_26990	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_26995	COG1024	Enoyl-CoA hydratase
WT60_27000	COG1024	Enoyl-CoA hydratase
WT60_27015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WT60_27020	COG1960	acyl-CoA dehydrogenase activity
WT60_27035	COG0330	HflC and HflK could
WT60_27060	COG0028	Belongs to the TPP enzyme family
WT60_27060	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
WT60_27070	COG1012	belongs to the aldehyde dehydrogenase family
WT60_27110	COG2252	PERMEase
WT60_27125	COG3284	Transcriptional regulator
WT60_27140	COG0410	ABC transporter
WT60_27195	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT60_27200	COG3246	L-lysine catabolic process to acetate
WT60_27245	COG2113	Glycine betaine
WT60_27265	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WT60_27270	COG0247	lactate metabolic process
WT60_27270	COG2181	nitrate reductase activity
WT60_27275	COG1902	pentaerythritol trinitrate reductase activity
WT60_27275	COG0446	pyridine nucleotide-disulphide oxidoreductase
WT60_27325	COG2814	Major facilitator Superfamily
WT60_27395	COG3501	Rhs element vgr protein
WT60_27400	COG3501	Rhs element vgr protein
WT60_27475	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
WT60_27475	COG0028	Belongs to the TPP enzyme family
WT60_27480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WT60_27490	COG4977	sequence-specific DNA binding
WT60_27500	COG0583	DNA-binding transcription factor activity
WT60_27520	COG1305	Transglutaminase-like
WT60_27545	COG2308	Evidence 4 Homologs of previously reported genes of
WT60_27570	COG0450	alkyl hydroperoxide reductase
WT60_27595	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_27610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WT60_27640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT60_27645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WT60_27650	COG1116	anion transmembrane transporter activity
WT60_27675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WT60_27690	COG0010	Belongs to the arginase family
WT60_27695	COG1012	belongs to the aldehyde dehydrogenase family
WT60_27705	COG0519	Catalyzes the synthesis of GMP from XMP
WT60_27705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WT60_27710	COG0174	glutamine synthetase
WT60_27720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WT60_27725	COG3842	ATPase activity
WT60_27730	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT60_27735	COG1177	transmembrane transport
WT60_27745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT60_27755	COG0477	Major facilitator Superfamily
WT60_27760	COG1309	transcriptional regulator
WT60_27780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WT60_27805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT60_27810	COG0840	transmembrane signaling receptor activity
WT60_27850	COG1796	DNA polymerase
WT60_27850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WT60_27855	COG2755	lipolytic protein G-D-S-L family
WT60_27855	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT60_27880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT60_27885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WT60_27925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WT60_27960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WT60_28005	COG3193	protein, possibly involved in utilization of glycolate and propanediol
WT60_28020	COG4633	Protein conserved in bacteria
WT60_28030	COG0556	nucleotide-excision repair
WT60_28040	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_28045	COG0667	Aldo Keto reductase
WT60_28050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WT60_28060	COG0789	Transcriptional regulator
WT60_28070	COG3436	PFAM IS66 Orf2 family protein
WT60_28075	COG2963	transposase activity
WT60_28080	COG2801	Transposase and inactivated derivatives
WT60_28085	COG4372	Transposase
WT60_28120	COG1012	belongs to the aldehyde dehydrogenase family
WT60_28135	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT60_28155	COG2271	Major facilitator Superfamily
WT60_28160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WT60_28165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WT60_28175	COG1620	l-lactate permease
WT60_28185	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WT60_28215	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WT60_28215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT60_28225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WT60_28230	COG0531	amino acid
WT60_28240	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WT60_28265	COG2837	iron assimilation
WT60_28280	COG3842	ATPase activity
WT60_28285	COG2259	Doxx family
WT60_28290	COG1620	l-lactate permease
WT60_28295	COG1556	Lactate utilization protein
WT60_28300	COG1139	Iron-sulfur cluster binding protein
WT60_28305	COG0247	lactate metabolic process
WT60_28310	COG2186	Transcriptional regulator
WT60_28330	COG2011	ABC-type metal ion transport system permease component
WT60_28335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WT60_28355	COG2197	response regulator
WT60_28380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WT60_28385	COG1012	belongs to the aldehyde dehydrogenase family
WT60_28390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT60_28390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT60_28390	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_28390	COG3321	synthase
WT60_28390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WT60_28395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WT60_28405	COG0019	diaminopimelate decarboxylase activity
WT60_28410	COG0318	PFAM AMP-dependent synthetase and ligase
WT60_28445	COG1301	dicarboxylic acid transport
WT60_28465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT60_28475	COG0583	DNA-binding transcription factor activity
WT60_28495	COG1942	4-Oxalocrotonate Tautomerase
WT60_28500	COG0583	DNA-binding transcription factor activity
WT60_28505	COG0709	Synthesizes selenophosphate from selenide and ATP
WT60_28520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WT60_28535	COG0840	transmembrane signaling receptor activity
WT60_28540	COG0183	Belongs to the thiolase family
WT60_28545	COG1414	Transcriptional regulator
WT60_28550	COG1309	transcriptional regulator
WT60_28560	COG1473	amidohydrolase
WT60_28565	COG0583	DNA-binding transcription factor activity
WT60_28570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT60_28590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_28615	COG2376	Dihydroxyacetone kinase
WT60_28620	COG1063	alcohol dehydrogenase
WT60_28625	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_28630	COG1879	ABC-type sugar transport system periplasmic component
WT60_28635	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT60_28640	COG1129	ABC transporter
WT60_28645	COG0698	ribose 5-phosphate isomerase
WT60_28660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_28675	COG1840	ABC-type Fe3 transport system, periplasmic component
WT60_28680	COG3842	ATPase activity
WT60_28700	COG4771	TonB-dependent receptor
WT60_28705	COG3720	iron ion transport
WT60_28710	COG4558	Periplasmic binding protein
WT60_28715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WT60_28725	COG2860	membrane
WT60_28740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
WT60_28750	COG1271	oxidase subunit
WT60_28755	COG1294	oxidase, subunit
WT60_28770	COG1562	ergosterol biosynthetic process
WT60_28780	COG0346	lactoylglutathione lyase activity
WT60_28790	COG1368	sulfuric ester hydrolase activity
WT60_28830	COG2814	Major facilitator Superfamily
WT60_28840	COG1285	pathogenesis
WT60_28860	COG0840	transmembrane signaling receptor activity
WT60_28865	COG0535	radical SAM domain protein
WT60_28920	COG0840	transmembrane signaling receptor activity
WT60_28935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
WT60_28960	COG4771	TonB-dependent receptor
WT60_28975	COG2226	methyltransferase
WT60_28975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT60_28975	COG3433	isochorismatase activity
WT60_28995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
WT60_29000	COG1021	2,3-dihydroxybenzoate-AMP ligase
WT60_29025	COG0179	Fumarylacetoacetate (FAA) hydrolase
WT60_29060	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT60_29075	COG2610	gluconate transmembrane transporter activity
WT60_29110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WT60_29115	COG0601	transmembrane transport
WT60_29120	COG4166	transmembrane transport
WT60_29130	COG3104	oligopeptide transport
WT60_29165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT60_29185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WT60_29190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WT60_29215	COG1566	PFAM secretion protein HlyD family protein
WT60_29230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WT60_29240	COG2879	small protein
WT60_29245	COG1966	Carbon starvation protein
WT60_29275	COG2814	Major facilitator Superfamily
WT60_29325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT60_29340	COG1012	belongs to the aldehyde dehydrogenase family
WT60_29355	COG4172	Belongs to the ABC transporter superfamily
WT60_29360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WT60_29365	COG0601	transmembrane transport
WT60_29395	COG0463	Glycosyl transferase, family 2
WT60_29435	COG4964	Belongs to the GSP D family
WT60_29480	COG1522	sequence-specific DNA binding
WT60_29500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_29505	COG1113	amino acid transport
WT60_29525	COG0583	DNA-binding transcription factor activity
WT60_29560	COG2084	Dehydrogenase
WT60_29565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WT60_29570	COG2091	lysine biosynthetic process via aminoadipic acid
WT60_29585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WT60_29615	COG0022	dehydrogenase e1 component
WT60_29675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WT60_29730	COG0071	Belongs to the small heat shock protein (HSP20) family
WT60_29735	COG0243	molybdopterin cofactor binding
WT60_29740	COG0437	4 iron, 4 sulfur cluster binding
WT60_29745	COG3302	dmso reductase anchor subunit
WT60_29780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT60_29805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT60_29820	COG0154	amidase activity
WT60_29830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT60_29840	COG0454	-acetyltransferase
WT60_29840	COG0456	acetyltransferase
WT60_29860	COG4172	Belongs to the ABC transporter superfamily
WT60_29865	COG4239	(ABC) transporter, permease
WT60_29870	COG4174	ABC transporter (Permease)
WT60_29880	COG4771	TonB-dependent receptor
WT60_29885	COG1396	sequence-specific DNA binding
WT60_29935	COG5002	protein histidine kinase activity
WT60_29935	COG5001	Diguanylate cyclase
WT60_29945	COG2091	lysine biosynthetic process via aminoadipic acid
WT60_29965	COG0577	efflux transmembrane transporter activity
WT60_29965	COG1136	(ABC) transporter
WT60_29970	COG1136	(ABC) transporter
WT60_29975	COG2072	flavoprotein involved in K transport
WT60_29985	COG1028	Short-chain dehydrogenase reductase Sdr
WT60_30010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WT60_30020	COG1126	abc transporter atp-binding protein
WT60_30025	COG0765	amino acid transport
WT60_30030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT60_30040	COG1657	PFAM Prenyltransferase squalene oxidase
WT60_30050	COG1562	ergosterol biosynthetic process
WT60_30065	COG3706	GGDEF domain
WT60_30075	COG2201	protein-glutamate methylesterase activity
WT60_30090	COG1595	DNA-templated transcription, initiation
WT60_30100	COG1393	Belongs to the ArsC family
WT60_30110	COG1192	Involved in chromosome partitioning