locus-tag	class	description
DR63_1001	COG0156	8-amino-7-oxononanoate synthase activity
DR63_1002	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DR63_1004	COG1368	sulfuric ester hydrolase activity
DR63_1013	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DR63_102	COG0670	Belongs to the BI1 family
DR63_1023	COG0586	Pfam SNARE associated Golgi protein
DR63_1024	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DR63_1028	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DR63_1030	COG0617	tRNA 3'-terminal CCA addition
DR63_1032	COG1428	Deoxynucleoside kinase
DR63_1034	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DR63_1043	COG0497	DNA recombination
DR63_1044	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DR63_1045	COG3164	Protein of unknown function
DR63_1046	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DR63_1047	COG0312	modulator of DNA gyrase
DR63_1048	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DR63_1049	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DR63_1049	COG1017	nitric oxide dioxygenase activity
DR63_1050	COG2096	Adenosyltransferase
DR63_1051	COG0277	FAD linked oxidase domain protein
DR63_1052	COG0277	FAD linked oxidase domain protein
DR63_1053	COG0277	FAD linked oxidase domain protein
DR63_1054	COG0247	lactate metabolic process
DR63_1058	COG0783	Belongs to the Dps family
DR63_1063	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DR63_1065	COG0343	queuine tRNA-ribosyltransferase activity
DR63_1066	COG1862	Preprotein translocase
DR63_1067	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DR63_1068	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DR63_1069	COG0477	Major facilitator Superfamily
DR63_1070	COG2353	YceI-like domain
DR63_1071	COG2353	YceI-like domain
DR63_1072	COG3038	cytochrome b561
DR63_1074	COG2995	paraquat-inducible protein a
DR63_1075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DR63_1075	COG3008	intermembrane lipid transfer
DR63_1082	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DR63_1083	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DR63_1084	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DR63_1087	COG0069	glutamate synthase activity
DR63_1088	COG0625	glutathione transferase activity
DR63_1089	COG0006	proline dipeptidase activity
DR63_1090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DR63_1091	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DR63_1092	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DR63_1099	COG0588	phosphoglycerate mutase activity
DR63_110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR63_1104	COG0625	glutathione transferase activity
DR63_1105	COG0625	glutathione transferase activity
DR63_1106	COG1917	Cupin 2, conserved barrel domain protein
DR63_1106	COG4977	sequence-specific DNA binding
DR63_1112	COG0418	dihydroorotase activity
DR63_1113	COG0121	glutamine amidotransferase
DR63_1114	COG1126	abc transporter atp-binding protein
DR63_1115	COG0765	amino acid transport
DR63_1116	COG0765	amino acid transport
DR63_1117	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR63_1118	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DR63_1119	COG0583	DNA-binding transcription factor activity
DR63_1120	COG2223	nitrite transmembrane transporter activity
DR63_1124	COG0800	Aldolase
DR63_1129	COG1466	dna polymerase III delta subunit
DR63_113	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DR63_1130	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DR63_1135	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DR63_1136	COG0735	belongs to the Fur family
DR63_1137	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DR63_1138	COG4266	Belongs to the allantoicase family
DR63_1139	COG1301	dicarboxylic acid transport
DR63_1141	COG0583	DNA-binding transcription factor activity
DR63_1144	COG2814	Major facilitator Superfamily
DR63_1145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DR63_1146	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DR63_1147	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DR63_1149	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DR63_115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DR63_1154	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DR63_1155	COG1546	Belongs to the CinA family
DR63_1156	COG0284	orotidine-5'-phosphate decarboxylase activity
DR63_1158	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_1159	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_116	COG0789	Transcriptional regulator
DR63_1162	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_1163	COG0800	Aldolase
DR63_1164	COG3734	2-keto-3-deoxy-galactonokinase
DR63_1165	COG1414	Transcriptional regulator
DR63_1170	COG0557	exoribonuclease II activity
DR63_1171	COG3150	esterase
DR63_1172	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DR63_1174	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DR63_1175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DR63_1176	COG0511	ligase activity, forming carbon-carbon bonds
DR63_1177	COG0439	Biotin carboxylase
DR63_118	COG3228	Belongs to the MtfA family
DR63_1180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DR63_1185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DR63_1185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DR63_1189	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DR63_1191	COG2095	MarC family integral membrane protein
DR63_1199	COG0142	geranyltranstransferase activity
DR63_1201	COG4536	flavin adenine dinucleotide binding
DR63_1202	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DR63_1204	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DR63_1207	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DR63_1208	COG0494	nUDIX hydrolase
DR63_121	COG0534	Mate efflux family protein
DR63_1214	COG0678	peroxiredoxin activity
DR63_1217	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DR63_1224	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DR63_1225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DR63_1227	COG3116	cell division
DR63_1232	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_1233	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_1234	COG0243	molybdopterin cofactor binding
DR63_1235	COG4372	Transposase
DR63_1236	COG3436	PFAM IS66 Orf2 family protein
DR63_1237	COG3328	transposase activity
DR63_1246	COG1012	belongs to the aldehyde dehydrogenase family
DR63_1249	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR63_1253	COG2271	Major facilitator Superfamily
DR63_1254	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DR63_1255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DR63_1257	COG1620	l-lactate permease
DR63_1258	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DR63_126	COG0542	response to heat
DR63_1263	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR63_1265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR63_1266	COG0531	amino acid
DR63_1268	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DR63_127	COG1959	2 iron, 2 sulfur cluster binding
DR63_1271	COG2259	Doxx family
DR63_1274	COG1620	l-lactate permease
DR63_1275	COG1556	Lactate utilization protein
DR63_1276	COG1139	Iron-sulfur cluster binding protein
DR63_1277	COG0247	lactate metabolic process
DR63_1278	COG2186	Transcriptional regulator
DR63_128	COG2346	COG2346, Truncated hemoglobins
DR63_1283	COG1464	Belongs to the NlpA lipoprotein family
DR63_1284	COG2197	response regulator
DR63_1288	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DR63_129	COG0314	molybdopterin synthase activity
DR63_1290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_1290	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_1290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_1290	COG3321	synthase
DR63_1290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_1291	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DR63_1293	COG0019	diaminopimelate decarboxylase activity
DR63_1294	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DR63_1302	COG1301	dicarboxylic acid transport
DR63_1305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR63_1307	COG0583	DNA-binding transcription factor activity
DR63_1308	COG3293	Transposase
DR63_1311	COG1942	4-Oxalocrotonate Tautomerase
DR63_1312	COG0583	DNA-binding transcription factor activity
DR63_1313	COG0709	Synthesizes selenophosphate from selenide and ATP
DR63_1316	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DR63_1325	COG0840	transmembrane signaling receptor activity
DR63_1326	COG0183	Belongs to the thiolase family
DR63_1327	COG1414	Transcriptional regulator
DR63_1328	COG1309	transcriptional regulator
DR63_1334	COG1464	Belongs to the NlpA lipoprotein family
DR63_1335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_134	COG0436	Aminotransferase
DR63_1340	COG3720	iron ion transport
DR63_1341	COG4558	Periplasmic binding protein
DR63_1342	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DR63_1344	COG2860	membrane
DR63_1346	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DR63_1348	COG1271	oxidase subunit
DR63_1349	COG1294	oxidase, subunit
DR63_1352	COG1902	pentaerythritol trinitrate reductase activity
DR63_1353	COG0656	L-ascorbic acid biosynthetic process
DR63_1354	COG2814	Major facilitator Superfamily
DR63_1355	COG0583	DNA-binding transcription factor activity
DR63_1356	COG1562	ergosterol biosynthetic process
DR63_1359	COG0583	DNA-binding transcription factor activity
DR63_136	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DR63_1360	COG0778	Nitroreductase
DR63_1362	COG0583	DNA-binding transcription factor activity
DR63_1363	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DR63_137	COG2076	Multidrug Resistance protein
DR63_1376	COG1285	pathogenesis
DR63_1378	COG2942	2-epimerase
DR63_138	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DR63_1381	COG0840	transmembrane signaling receptor activity
DR63_1382	COG0535	radical SAM domain protein
DR63_139	COG0463	Glycosyl transferase, family 2
DR63_1392	COG0840	transmembrane signaling receptor activity
DR63_1398	COG2814	Major facilitator Superfamily
DR63_1400	COG0179	Fumarylacetoacetate (FAA) hydrolase
DR63_1406	COG2916	Histone family protein nucleoid-structuring protein H-NS
DR63_141	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_141	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DR63_1410	COG2610	gluconate transmembrane transporter activity
DR63_1416	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DR63_1417	COG0601	transmembrane transport
DR63_142	COG0726	polysaccharide deacetylase
DR63_1420	COG3104	oligopeptide transport
DR63_1425	COG2079	MmgE PrpD family protein
DR63_1426	COG2301	Belongs to the HpcH HpaI aldolase family
DR63_1427	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR63_1429	COG1335	isochorismatase
DR63_143	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DR63_1430	COG0477	Major facilitator Superfamily
DR63_1431	COG2271	Major facilitator Superfamily
DR63_1433	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR63_1436	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_144	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DR63_1441	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_1445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DR63_1446	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DR63_145	COG0791	NLP P60 protein
DR63_1451	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DR63_1453	COG2879	small protein
DR63_1454	COG1966	Carbon starvation protein
DR63_146	COG0306	phosphate transporter
DR63_1461	COG0463	Glycosyl transferase, family 2
DR63_1469	COG4964	Belongs to the GSP D family
DR63_1478	COG3293	Transposase
DR63_148	COG0305	Participates in initiation and elongation during chromosome replication
DR63_1480	COG1522	sequence-specific DNA binding
DR63_1483	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_1484	COG1113	amino acid transport
DR63_1487	COG2271	Major facilitator Superfamily
DR63_1495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DR63_1496	COG2091	lysine biosynthetic process via aminoadipic acid
DR63_1498	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DR63_15	COG3264	Mechanosensitive ion channel
DR63_15	COG1196	nuclear chromosome segregation
DR63_1503	COG0022	dehydrogenase e1 component
DR63_1511	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DR63_1521	COG0071	Belongs to the small heat shock protein (HSP20) family
DR63_1530	COG0154	amidase activity
DR63_1531	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR63_1537	COG5001	Diguanylate cyclase
DR63_1537	COG3447	MASE1 domain protein
DR63_1537	COG5002	protein histidine kinase activity
DR63_1539	COG2091	lysine biosynthetic process via aminoadipic acid
DR63_1544	COG1136	(ABC) transporter
DR63_1545	COG2072	flavoprotein involved in K transport
DR63_1547	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_1552	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DR63_1554	COG1126	abc transporter atp-binding protein
DR63_1555	COG0765	amino acid transport
DR63_1556	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR63_1559	COG1657	PFAM Prenyltransferase squalene oxidase
DR63_1561	COG1562	ergosterol biosynthetic process
DR63_1563	COG3706	GGDEF domain
DR63_1565	COG2201	protein-glutamate methylesterase activity
DR63_1568	COG1595	DNA-templated transcription, initiation
DR63_157	COG0583	DNA-binding transcription factor activity
DR63_1570	COG1393	Belongs to the ArsC family
DR63_1571	COG1192	Involved in chromosome partitioning
DR63_1577	COG1396	sequence-specific DNA binding
DR63_158	COG3960	tartronate-semialdehyde synthase activity
DR63_1580	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DR63_1584	COG1309	transcriptional regulator
DR63_1587	COG0473	3-isopropylmalate dehydrogenase activity
DR63_1588	COG0583	DNA-binding transcription factor activity
DR63_159	COG3622	Belongs to the hyi family
DR63_1590	COG0625	glutathione transferase activity
DR63_1593	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_1595	COG0671	phosphoesterase, PA-phosphatase related
DR63_1599	COG1695	Transcriptional regulator
DR63_160	COG2084	Dehydrogenase
DR63_1605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DR63_1609	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DR63_161	COG1652	LysM domain
DR63_1610	COG0589	response to stress
DR63_1615	COG1045	serine acetyltransferase
DR63_1616	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_1617	COG0302	gtp cyclohydrolase
DR63_162	COG0252	asparaginase activity
DR63_1621	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DR63_1623	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DR63_1624	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DR63_1629	COG0446	pyridine nucleotide-disulphide oxidoreductase
DR63_1634	COG0640	Transcriptional regulator
DR63_1636	COG1136	(ABC) transporter
DR63_1636	COG0577	efflux transmembrane transporter activity
DR63_1645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DR63_1652	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DR63_166	COG0438	transferase activity, transferring glycosyl groups
DR63_1660	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR63_1661	COG1177	transmembrane transport
DR63_1664	COG3501	Rhs element vgr protein
DR63_1673	COG0582	viral genome integration into host DNA
DR63_1680	COG0592	DNA-directed DNA polymerase activity
DR63_1682	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DR63_1683	COG3328	transposase activity
DR63_1684	COG0583	DNA-binding transcription factor activity
DR63_1685	COG0477	Major facilitator Superfamily
DR63_1686	COG1012	belongs to the aldehyde dehydrogenase family
DR63_1687	COG2207	Transcriptional regulator
DR63_1690	COG1760	l-serine dehydratase
DR63_1693	COG0509	glycine decarboxylation via glycine cleavage system
DR63_1696	COG0673	inositol 2-dehydrogenase activity
DR63_1699	COG0210	DNA helicase
DR63_171	COG0084	hydrolase, TatD family'
DR63_1713	COG3293	Transposase
DR63_1714	COG0582	viral genome integration into host DNA
DR63_1717	COG3328	transposase activity
DR63_1719	COG0583	DNA-binding transcription factor activity
DR63_172	COG1247	-acetyltransferase
DR63_1720	COG4302	ethanolamine ammonia-lyase activity
DR63_1721	COG4303	Ethanolamine ammonia lyase large subunit
DR63_1722	COG0531	amino acid
DR63_1724	COG0668	transmembrane transport
DR63_1727	COG0789	Transcriptional regulator
DR63_1731	COG0436	Aminotransferase
DR63_1733	COG1960	acyl-CoA dehydrogenase activity
DR63_1735	COG0683	leucine binding
DR63_1736	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DR63_1736	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DR63_1736	COG0506	proline dehydrogenase activity
DR63_1738	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DR63_1741	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_1749	COG0356	it plays a direct role in the translocation of protons across the membrane
DR63_175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DR63_1751	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DR63_1752	COG1475	DNA binding
DR63_1753	COG1192	Involved in chromosome partitioning
DR63_1757	COG0411	ABC transporter
DR63_176	COG0354	folic acid binding
DR63_1765	COG0411	ABC transporter
DR63_1768	COG0583	DNA-binding transcription factor activity
DR63_1770	COG1522	sequence-specific DNA binding
DR63_1771	COG3186	Phenylalanine-4-hydroxylase
DR63_1772	COG2154	pterin-4-alpha-carbinolamine dehydratase
DR63_1775	COG0642	Histidine kinase
DR63_1777	COG1902	pentaerythritol trinitrate reductase activity
DR63_1778	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DR63_1778	COG0519	Catalyzes the synthesis of GMP from XMP
DR63_178	COG2153	protein acetylation
DR63_1784	COG0523	cobalamin synthesis protein
DR63_1785	COG0741	lytic transglycosylase activity
DR63_180	COG2130	NADP-dependent
DR63_1800	COG1846	Transcriptional regulator
DR63_1801	COG2814	Major facilitator Superfamily
DR63_1802	COG0583	DNA-binding transcription factor activity
DR63_1804	COG1346	cytolysis
DR63_1807	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DR63_1809	COG1338	Plays a role in the flagellum-specific transport system
DR63_1810	COG1987	bacterial-type flagellum assembly
DR63_1812	COG0789	Transcriptional regulator
DR63_1813	COG2226	methyltransferase
DR63_1814	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DR63_1816	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DR63_1819	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_1822	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_1834	COG1695	Transcriptional regulator
DR63_1839	COG1960	acyl-CoA dehydrogenase activity
DR63_184	COG0183	Belongs to the thiolase family
DR63_1840	COG0183	Belongs to the thiolase family
DR63_1841	COG1024	Enoyl-CoA hydratase
DR63_1841	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR63_1842	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR63_1849	COG0753	catalase activity
DR63_185	COG1335	isochorismatase
DR63_1854	COG1475	DNA binding
DR63_1859	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DR63_186	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR63_186	COG1024	Enoyl-CoA hydratase
DR63_1861	COG4681	YaeQ
DR63_1864	COG2169	Transcriptional regulator
DR63_1864	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DR63_1867	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DR63_187	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_1872	COG4974	Belongs to the 'phage' integrase family
DR63_1874	COG0582	viral genome integration into host DNA
DR63_1884	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DR63_19	COG2350	Protein conserved in bacteria
DR63_1907	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DR63_1908	COG0583	DNA-binding transcription factor activity
DR63_1911	COG0758	DNA mediated transformation
DR63_1912	COG0242	peptide deformylase activity
DR63_1916	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DR63_1916	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DR63_1918	COG5000	phosphorelay sensor kinase activity
DR63_1919	COG2204	response regulator
DR63_192	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DR63_1922	COG0602	queuosine metabolic process
DR63_1923	COG0720	synthase
DR63_1926	COG0772	Belongs to the SEDS family
DR63_1927	COG0768	penicillin binding
DR63_193	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DR63_193	COG0047	phosphoribosylformylglycinamidine synthase activity
DR63_1930	COG1077	Cell shape determining protein MreB Mrl
DR63_1934	COG2326	polyphosphate kinase activity
DR63_1935	COG0708	Exodeoxyribonuclease III
DR63_1936	COG1064	alcohol dehydrogenase
DR63_1937	COG2207	Transcriptional regulator
DR63_1939	COG2814	Major facilitator Superfamily
DR63_194	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR63_1942	COG1309	transcriptional regulator
DR63_1947	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DR63_1949	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DR63_1950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DR63_1951	COG0523	cobalamin synthesis protein
DR63_1953	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DR63_1956	COG1560	Kdo2-lipid A biosynthetic process
DR63_1961	COG0667	Aldo Keto reductase
DR63_1964	COG2814	Major facilitator Superfamily
DR63_1967	COG0583	DNA-binding transcription factor activity
DR63_1968	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR63_197	COG4181	ATPase activity
DR63_1970	COG2271	Major facilitator Superfamily
DR63_1971	COG4948	Mandelate Racemase Muconate Lactonizing
DR63_1973	COG2721	sulfolactate sulfo-lyase activity
DR63_1974	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_1976	COG1960	acyl-CoA dehydrogenase activity
DR63_1980	COG1157	protein secretion by the type III secretion system
DR63_1982	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DR63_1988	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR63_199	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DR63_1991	COG0531	amino acid
DR63_1993	COG3851	Histidine kinase
DR63_1996	COG3568	Endonuclease Exonuclease Phosphatase
DR63_1999	COG0579	oxidoreductase
DR63_2	COG2376	Dihydroxyacetone kinase
DR63_20	COG0598	Magnesium transport protein CorA
DR63_2001	COG0477	Major facilitator Superfamily
DR63_2002	COG0747	negative chemotaxis
DR63_2003	COG0601	transmembrane transport
DR63_2004	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DR63_2005	COG0444	Belongs to the ABC transporter superfamily
DR63_2006	COG4608	Belongs to the ABC transporter superfamily
DR63_2011	COG1984	allophanate hydrolase subunit 2
DR63_2012	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DR63_2014	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DR63_2015	COG0741	lytic transglycosylase activity
DR63_2020	COG2747	anti-sigma28 factor FlgM
DR63_2022	COG1815	bacterial-type flagellum-dependent cell motility
DR63_2023	COG1558	bacterial-type flagellum-dependent cell motility
DR63_2024	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DR63_2025	COG1749	Flagellar hook protein flgE
DR63_2027	COG4786	Flagellar basal body rod
DR63_2028	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DR63_2029	COG1706	bacterial-type flagellum-dependent cell motility
DR63_2031	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DR63_2032	COG1256	bacterial-type flagellum assembly
DR63_2033	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DR63_2034	COG2233	PERMEase
DR63_2035	COG0583	DNA-binding transcription factor activity
DR63_2039	COG2824	Alkylphosphonate utilization operon protein PhnA
DR63_2042	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_2047	COG3293	Transposase
DR63_2057	COG0745	RESPONSE REGULATOR receiver
DR63_206	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DR63_2065	COG2217	Heavy metal translocating P-type atpase
DR63_2067	COG1704	LemA family
DR63_2068	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DR63_2071	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DR63_2081	COG1609	Transcriptional regulator
DR63_2082	COG0840	transmembrane signaling receptor activity
DR63_2085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_2086	COG0583	DNA-binding transcription factor activity
DR63_2088	COG0596	Alpha beta hydrolase
DR63_2094	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DR63_2097	COG3511	phospholipase C
DR63_210	COG1929	Belongs to the glycerate kinase type-1 family
DR63_2102	COG0596	Alpha beta hydrolase
DR63_2103	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR63_2104	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DR63_2109	COG0025	NhaP-type Na H and K H
DR63_211	COG1846	Transcriptional regulator
DR63_2110	COG2200	EAL domain
DR63_2110	COG2199	diguanylate cyclase activity
DR63_2112	COG1785	Belongs to the alkaline phosphatase family
DR63_212	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DR63_2122	COG3012	SEC-C Motif Domain Protein
DR63_2124	COG0183	Belongs to the thiolase family
DR63_2125	COG0288	reversible hydration of carbon dioxide
DR63_2129	COG0747	negative chemotaxis
DR63_2131	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_2132	COG0300	oxidoreductase activity
DR63_2133	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DR63_2143	COG1024	Enoyl-CoA hydratase
DR63_2147	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DR63_2152	COG0737	Belongs to the 5'-nucleotidase family
DR63_2153	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DR63_2154	COG1127	ABC transporter
DR63_2160	COG1686	Belongs to the peptidase S11 family
DR63_2162	COG2921	Belongs to the UPF0250 family
DR63_2163	COG0583	DNA-binding transcription factor activity
DR63_2168	COG0583	DNA-binding transcription factor activity
DR63_2169	COG0405	Gamma-glutamyltransferase
DR63_2171	COG0583	DNA-binding transcription factor activity
DR63_2172	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR63_2172	COG1024	Enoyl-CoA hydratase
DR63_2173	COG1960	acyl-CoA dehydrogenase activity
DR63_2174	COG1960	acyl-CoA dehydrogenase activity
DR63_2175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR63_2177	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DR63_2179	COG4191	Histidine kinase
DR63_2180	COG2204	response regulator
DR63_2181	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DR63_2185	COG2960	long-chain fatty acid transporting porin activity
DR63_2187	COG0004	ammonium transporteR
DR63_2189	COG0189	ligase activity
DR63_2191	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DR63_2192	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DR63_2193	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DR63_2194	COG0793	Belongs to the peptidase S41A family
DR63_2196	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DR63_2200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DR63_2203	COG2226	methyltransferase
DR63_2206	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DR63_2213	COG1612	heme a metabolic process
DR63_2215	COG1999	signal sequence binding
DR63_2217	COG0840	transmembrane signaling receptor activity
DR63_2221	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DR63_2224	COG0587	DNA-directed DNA polymerase activity
DR63_2225	COG2188	Transcriptional regulator
DR63_2226	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DR63_2227	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DR63_2228	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DR63_2228	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DR63_2229	COG2190	(PTS) system
DR63_2229	COG1263	PTS System
DR63_2229	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DR63_2233	COG1294	oxidase, subunit
DR63_2236	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DR63_2237	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DR63_2239	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DR63_2241	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DR63_2242	COG0243	molybdopterin cofactor binding
DR63_2244	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DR63_2245	COG0625	glutathione transferase activity
DR63_2247	COG0742	ribosomal rna small subunit methyltransferase
DR63_2249	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DR63_2253	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DR63_2259	COG1194	a g-specific adenine glycosylase
DR63_2264	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DR63_2265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DR63_2266	COG1137	ATPase activity
DR63_2269	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DR63_2273	COG1280	lysine exporter protein (LysE YggA)
DR63_2278	COG2814	Major facilitator Superfamily
DR63_2279	COG0629	single-stranded DNA binding
DR63_2280	COG0412	Dienelactone hydrolase
DR63_2284	COG3328	transposase activity
DR63_2286	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DR63_2298	COG0235	Class ii aldolase
DR63_2299	COG5002	protein histidine kinase activity
DR63_2299	COG5001	Diguanylate cyclase
DR63_230	COG0745	RESPONSE REGULATOR receiver
DR63_2306	COG2204	response regulator
DR63_231	COG2205	protein histidine kinase activity
DR63_2310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DR63_2312	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_2315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DR63_2316	COG1596	polysaccharide export
DR63_2321	COG0477	Major facilitator Superfamily
DR63_2326	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DR63_2327	COG0251	oxidation-reduction process
DR63_2329	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DR63_233	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DR63_2341	COG0494	nUDIX hydrolase
DR63_2344	COG1960	acyl-CoA dehydrogenase activity
DR63_2345	COG1024	Enoyl-CoA hydratase
DR63_2345	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR63_2346	COG0183	Belongs to the thiolase family
DR63_2347	COG1024	Enoyl-CoA hydratase
DR63_2348	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DR63_2350	COG1607	acyl-coa hydrolase
DR63_2351	COG5265	(ABC) transporter
DR63_2352	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DR63_2356	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DR63_236	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DR63_2361	COG0204	Acyl-transferase
DR63_2362	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DR63_2363	COG0751	glycine-tRNA ligase activity
DR63_2364	COG0752	glycyl-tRNA synthetase alpha subunit
DR63_2365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DR63_2367	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DR63_2369	COG1702	phosphate starvation-inducible protein PhoH
DR63_2371	COG0583	DNA-binding transcription factor activity
DR63_2372	COG2814	Major facilitator Superfamily
DR63_2374	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DR63_2375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DR63_2376	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DR63_2385	COG0513	Belongs to the DEAD box helicase family
DR63_2389	COG4948	Mandelate Racemase Muconate Lactonizing
DR63_2395	COG0840	transmembrane signaling receptor activity
DR63_2397	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DR63_2399	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DR63_24	COG0039	L-malate dehydrogenase activity
DR63_2409	COG0583	DNA-binding transcription factor activity
DR63_2410	COG2205	protein histidine kinase activity
DR63_2410	COG0784	Response regulator, receiver
DR63_2417	COG0642	Histidine kinase
DR63_2419	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DR63_2420	COG2137	regulation of response to DNA damage stimulus
DR63_2423	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DR63_2424	COG0861	Integral membrane protein TerC family
DR63_2425	COG4969	Belongs to the N-Me-Phe pilin family
DR63_2426	COG3307	-O-antigen
DR63_2430	COG4783	chaperone-mediated protein folding
DR63_2432	COG0429	hydrolase of the alpha beta-hydrolase fold
DR63_2434	COG0859	PFAM glycosyl transferase family 9
DR63_2439	COG0126	phosphoglycerate kinase activity
DR63_2440	COG0469	pyruvate kinase activity
DR63_2442	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DR63_2443	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DR63_2444	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DR63_2445	COG0009	L-threonylcarbamoyladenylate synthase
DR63_2449	COG0745	RESPONSE REGULATOR receiver
DR63_2451	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR63_2456	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR63_2457	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR63_2458	COG1538	Outer membrane efflux protein
DR63_2459	COG2233	PERMEase
DR63_2460	COG1070	Carbohydrate kinase
DR63_2463	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DR63_2464	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DR63_2465	COG1121	(ABC) transporter
DR63_2467	COG0735	belongs to the Fur family
DR63_2469	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR63_2472	COG1175	transmembrane transport
DR63_2474	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DR63_2477	COG2390	Transcriptional regulator
DR63_2478	COG1070	Carbohydrate kinase
DR63_2479	COG0246	Mannitol dehydrogenase
DR63_2480	COG0583	DNA-binding transcription factor activity
DR63_2482	COG1012	belongs to the aldehyde dehydrogenase family
DR63_2488	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DR63_2489	COG1522	sequence-specific DNA binding
DR63_249	COG3360	Dodecin
DR63_2490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DR63_2492	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DR63_2494	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DR63_2495	COG3118	belongs to the thioredoxin family
DR63_2496	COG1741	Belongs to the pirin family
DR63_2498	COG0860	N-Acetylmuramoyl-L-alanine amidase
DR63_2499	COG0802	atpase or kinase
DR63_2500	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DR63_2502	COG4974	Belongs to the 'phage' integrase family
DR63_2503	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_2504	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DR63_2508	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DR63_2513	COG0728	peptidoglycan biosynthetic process
DR63_2521	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DR63_2526	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DR63_2529	COG2814	Major facilitator Superfamily
DR63_2532	COG2188	Transcriptional regulator
DR63_2533	COG0656	L-ascorbic acid biosynthetic process
DR63_2539	COG1278	Cold shock
DR63_2541	COG0542	response to heat
DR63_2542	COG1113	amino acid transport
DR63_2549	COG0196	riboflavin kinase activity
DR63_2550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DR63_2551	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DR63_2551	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DR63_2552	COG3264	Mechanosensitive ion channel
DR63_2552	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DR63_2556	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DR63_2557	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DR63_256	COG4266	Belongs to the allantoicase family
DR63_2560	COG1047	Peptidyl-prolyl cis-trans
DR63_2561	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DR63_2568	COG0456	acetyltransferase
DR63_2569	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DR63_257	COG3195	allantoin biosynthetic process
DR63_257	COG3648	Uricase
DR63_2570	COG0543	2 iron, 2 sulfur cluster binding
DR63_2570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DR63_2573	COG1187	pseudouridine synthase activity
DR63_2575	COG0583	DNA-binding transcription factor activity
DR63_2577	COG2267	carboxylic ester hydrolase activity
DR63_2578	COG2258	MOSC domain
DR63_2579	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR63_2580	COG0235	Class ii aldolase
DR63_2581	COG1396	sequence-specific DNA binding
DR63_2589	COG0583	DNA-binding transcription factor activity
DR63_2592	COG0175	sulfate reduction
DR63_2594	COG2895	sulfate adenylyltransferase (ATP) activity
DR63_2595	COG1648	precorrin-2 dehydrogenase activity
DR63_2595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DR63_2598	COG0795	lipopolysaccharide-transporting ATPase activity
DR63_260	COG1953	Uracil, thiamine, allantoin
DR63_2602	COG4654	Cytochrome c, class I
DR63_2604	COG0583	DNA-binding transcription factor activity
DR63_2610	COG4206	TonB-dependent receptor
DR63_2612	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DR63_2613	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DR63_2614	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DR63_2616	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DR63_2618	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DR63_262	COG1619	proteins homologs of microcin C7 resistance protein MccF
DR63_2620	COG1492	cobalamin metabolic process
DR63_2621	COG2259	Doxx family
DR63_2622	COG0489	protein tyrosine kinase activity
DR63_2625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DR63_2627	COG0729	surface antigen
DR63_263	COG0590	tRNA wobble adenosine to inosine editing
DR63_2632	COG3047	cAMP biosynthetic process
DR63_2632	COG2885	chlorophyll binding
DR63_2633	COG0489	protein tyrosine kinase activity
DR63_2636	COG1982	Orn Lys Arg decarboxylase major
DR63_2638	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DR63_2645	COG2226	methyltransferase
DR63_2650	COG2271	Major facilitator Superfamily
DR63_2653	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DR63_2654	COG2827	Endonuclease containing a URI domain
DR63_2658	COG0347	Belongs to the P(II) protein family
DR63_2663	COG4160	amino acid transport
DR63_2664	COG4215	(ABC) transporter
DR63_2666	COG1741	Belongs to the pirin family
DR63_2668	COG0745	RESPONSE REGULATOR receiver
DR63_2671	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR63_2672	COG1116	anion transmembrane transporter activity
DR63_2676	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DR63_2679	COG2814	Major facilitator Superfamily
DR63_2680	COG1881	PFAM PEBP family protein
DR63_2688	COG3328	transposase activity
DR63_2699	COG3293	Transposase
DR63_2706	COG0582	viral genome integration into host DNA
DR63_2716	COG2204	response regulator
DR63_2717	COG1773	rubredoxin
DR63_272	COG0697	spore germination
DR63_2720	COG0187	DNA topoisomerase II activity
DR63_2723	COG0583	DNA-binding transcription factor activity
DR63_2731	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR63_2732	COG0697	spore germination
DR63_2741	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DR63_2743	COG3135	benzoate transporter
DR63_2750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DR63_2751	COG2878	Part of a membrane complex involved in electron transport
DR63_2752	COG1309	transcriptional regulator
DR63_2754	COG3387	PFAM Glycoside hydrolase 15-related
DR63_2755	COG2706	6-phosphogluconolactonase activity
DR63_2756	COG1674	ftsk spoiiie
DR63_276	COG0330	HflC and HflK could
DR63_2762	COG0513	Belongs to the DEAD box helicase family
DR63_2763	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DR63_2771	COG0859	PFAM glycosyl transferase family 9
DR63_2777	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DR63_2778	COG1595	DNA-templated transcription, initiation
DR63_2788	COG2233	PERMEase
DR63_2789	COG1530	ribonuclease E activity
DR63_2792	COG0799	negative regulation of ribosome biogenesis
DR63_2795	COG0151	Belongs to the GarS family
DR63_2798	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_2803	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DR63_2804	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DR63_2806	COG2205	protein histidine kinase activity
DR63_2807	COG0745	RESPONSE REGULATOR receiver
DR63_2809	COG2076	Multidrug Resistance protein
DR63_2813	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DR63_2815	COG0154	amidase activity
DR63_2816	COG0477	Major facilitator Superfamily
DR63_2817	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DR63_2818	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_282	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DR63_2822	COG0438	transferase activity, transferring glycosyl groups
DR63_2828	COG0028	Belongs to the TPP enzyme family
DR63_2832	COG1183	phosphatidylcholine synthase activity
DR63_2834	COG0659	secondary active sulfate transmembrane transporter activity
DR63_2835	COG0288	reversible hydration of carbon dioxide
DR63_2837	COG0683	leucine binding
DR63_2841	COG0149	triose-phosphate isomerase activity
DR63_2848	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DR63_2850	COG1034	ATP synthesis coupled electron transport
DR63_2857	COG1007	ATP synthesis coupled electron transport
DR63_2859	COG0494	nUDIX hydrolase
DR63_2861	COG1960	acyl-CoA dehydrogenase activity
DR63_2862	COG1960	acyl-CoA dehydrogenase activity
DR63_2863	COG1012	belongs to the aldehyde dehydrogenase family
DR63_2863	COG2030	dehydratase
DR63_2866	COG1960	acyl-CoA dehydrogenase activity
DR63_2869	COG1024	Enoyl-CoA hydratase
DR63_2870	COG0625	glutathione transferase activity
DR63_2871	COG0436	Aminotransferase
DR63_2874	COG2866	Carboxypeptidase
DR63_2885	COG3328	transposase activity
DR63_2886	COG3436	PFAM IS66 Orf2 family protein
DR63_2888	COG0006	proline dipeptidase activity
DR63_2891	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DR63_2896	COG2863	cytochrome
DR63_2897	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DR63_2897	COG2010	Cytochrome c
DR63_290	COG0750	zinc metalloprotease
DR63_2900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DR63_2901	COG2863	cytochrome
DR63_2906	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR63_2907	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR63_2912	COG1959	2 iron, 2 sulfur cluster binding
DR63_2915	COG1522	sequence-specific DNA binding
DR63_2916	COG3842	ATPase activity
DR63_2917	COG1178	ABC-type Fe3 transport system permease component
DR63_2918	COG1840	ABC-type Fe3 transport system, periplasmic component
DR63_2922	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DR63_2923	COG1074	ATP-dependent DNA helicase activity
DR63_2924	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DR63_2926	COG2200	EAL domain
DR63_2928	COG0697	spore germination
DR63_293	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DR63_2934	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DR63_2935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DR63_2936	COG0697	spore germination
DR63_2937	COG2814	Major facilitator Superfamily
DR63_2941	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DR63_2942	COG3842	ATPase activity
DR63_2943	COG1177	transmembrane transport
DR63_2945	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DR63_2946	COG1840	ABC-type Fe3 transport system, periplasmic component
DR63_2947	COG1609	Transcriptional regulator
DR63_2952	COG3706	GGDEF domain
DR63_2958	COG0583	DNA-binding transcription factor activity
DR63_2967	COG0071	Belongs to the small heat shock protein (HSP20) family
DR63_2969	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DR63_2970	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR63_2971	COG0583	DNA-binding transcription factor activity
DR63_2975	COG3052	prosthetic group binding
DR63_2979	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DR63_298	COG0024	Methionine aminopeptidase
DR63_2981	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DR63_2984	COG0477	Major facilitator Superfamily
DR63_2986	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DR63_2987	COG0328	RNA-DNA hybrid ribonuclease activity
DR63_2988	COG2226	methyltransferase
DR63_2989	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DR63_2990	COG1388	LysM domain
DR63_2990	COG0741	lytic transglycosylase activity
DR63_2994	COG0505	Belongs to the CarA family
DR63_2996	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DR63_2997	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DR63_2999	COG1534	Rna-binding protein
DR63_300	COG1187	pseudouridine synthase activity
DR63_3001	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DR63_3002	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DR63_3004	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DR63_3005	COG0573	inorganic phosphate transmembrane transporter activity
DR63_3006	COG0581	inorganic phosphate transmembrane transporter activity
DR63_3009	COG0745	RESPONSE REGULATOR receiver
DR63_301	COG0242	peptide deformylase activity
DR63_3010	COG5002	protein histidine kinase activity
DR63_3011	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DR63_3021	COG0534	Mate efflux family protein
DR63_3023	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DR63_3025	COG4942	peptidase
DR63_3030	COG3328	transposase activity
DR63_3033	COG2963	transposase activity
DR63_3035	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DR63_3036	COG0732	type I restriction modification DNA specificity domain
DR63_3038	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DR63_3039	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DR63_3042	COG3436	PFAM IS66 Orf2 family protein
DR63_3055	COG5377	YqaJ viral recombinase family
DR63_3066	COG0582	viral genome integration into host DNA
DR63_3067	COG0583	DNA-binding transcription factor activity
DR63_3075	COG3501	Rhs element vgr protein
DR63_3085	COG3501	Rhs element vgr protein
DR63_309	COG1393	Belongs to the ArsC family
DR63_3094	COG3436	PFAM IS66 Orf2 family protein
DR63_3095	COG4372	Transposase
DR63_3096	COG1914	H( )-stimulated, divalent metal cation uptake system
DR63_3100	COG0583	DNA-binding transcription factor activity
DR63_3108	COG2197	response regulator
DR63_311	COG2890	protein-(glutamine-N5) methyltransferase activity
DR63_3111	COG3511	phospholipase C
DR63_3116	COG1051	belongs to the nudix hydrolase family
DR63_3117	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DR63_3120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR63_3123	COG0477	Major facilitator Superfamily
DR63_3124	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR63_3125	COG0494	nUDIX hydrolase
DR63_3128	COG0824	Thioesterase
DR63_3129	COG0559	Belongs to the binding-protein-dependent transport system permease family
DR63_313	COG0386	Belongs to the glutathione peroxidase family
DR63_3130	COG0411	ABC transporter
DR63_3132	COG3718	enzyme involved in inositol metabolism
DR63_3134	COG3962	Belongs to the TPP enzyme family
DR63_3137	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_314	COG0488	(ABC) transporter
DR63_3140	COG0673	inositol 2-dehydrogenase activity
DR63_3141	COG0673	inositol 2-dehydrogenase activity
DR63_3142	COG0425	Belongs to the sulfur carrier protein TusA family
DR63_3144	COG0745	RESPONSE REGULATOR receiver
DR63_3146	COG5002	protein histidine kinase activity
DR63_3148	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DR63_3149	COG0525	valine-tRNA ligase activity
DR63_3150	COG0210	DNA helicase
DR63_3151	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DR63_3152	COG2223	nitrite transmembrane transporter activity
DR63_3153	COG0840	transmembrane signaling receptor activity
DR63_3158	COG0583	DNA-binding transcription factor activity
DR63_3161	COG0277	FAD linked oxidase domain protein
DR63_3164	COG1295	ribonuclease BN
DR63_3167	COG0477	Major facilitator Superfamily
DR63_3170	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_3176	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_3179	COG0583	DNA-binding transcription factor activity
DR63_318	COG0477	Major facilitator Superfamily
DR63_3183	COG0251	oxidation-reduction process
DR63_3184	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DR63_3187	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DR63_319	COG0351	phosphomethylpyrimidine kinase
DR63_3192	COG0776	regulation of translation
DR63_3196	COG2963	transposase activity
DR63_3203	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DR63_321	COG1573	uracil-dna glycosylase
DR63_3211	COG0583	DNA-binding transcription factor activity
DR63_3212	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DR63_3213	COG1187	pseudouridine synthase activity
DR63_3215	COG2251	uridine kinase activity
DR63_3215	COG0195	Participates in both transcription termination and antitermination
DR63_3219	COG2814	Major facilitator Superfamily
DR63_3220	COG1566	PFAM secretion protein HlyD family protein
DR63_3222	COG1846	Transcriptional regulator
DR63_3224	COG0567	Dehydrogenase, E1 component
DR63_3225	COG0508	dehydrogenase complex catalyzes the overall conversion of
DR63_3226	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DR63_3227	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DR63_323	COG1214	PFAM Peptidase M22, glycoprotease
DR63_3237	COG4964	Belongs to the GSP D family
DR63_325	COG0513	Belongs to the DEAD box helicase family
DR63_3250	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_3252	COG2814	Major facilitator Superfamily
DR63_3253	COG0519	Catalyzes the synthesis of GMP from XMP
DR63_3257	COG0840	transmembrane signaling receptor activity
DR63_326	COG2224	Isocitrate lyase
DR63_3260	COG0557	exoribonuclease II activity
DR63_3261	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DR63_3262	COG3023	N-Acetylmuramoyl-L-alanine amidase
DR63_3264	COG1802	Transcriptional regulator
DR63_3265	COG0673	inositol 2-dehydrogenase activity
DR63_3278	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DR63_328	COG0583	DNA-binding transcription factor activity
DR63_3285	COG1301	dicarboxylic acid transport
DR63_3286	COG1733	regulation of RNA biosynthetic process
DR63_3288	COG0667	Aldo Keto reductase
DR63_3289	COG0701	Predicted permease
DR63_3297	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DR63_3298	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DR63_3299	COG4208	sulfate ABC transporter
DR63_33	COG1609	Transcriptional regulator
DR63_330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DR63_3300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DR63_3301	COG0583	DNA-binding transcription factor activity
DR63_3302	COG1879	ABC-type sugar transport system periplasmic component
DR63_3304	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_3305	COG1609	Transcriptional regulator
DR63_3306	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR63_3307	COG0840	transmembrane signaling receptor activity
DR63_3308	COG2766	serine protein kinase
DR63_3309	COG2718	Belongs to the UPF0229 family
DR63_3310	COG2719	SpoVR family
DR63_3311	COG0477	Major facilitator Superfamily
DR63_3316	COG4964	Belongs to the GSP D family
DR63_3325	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DR63_3326	COG4597	amino acid ABC transporter
DR63_3327	COG0765	amino acid transport
DR63_3328	COG0739	heme binding
DR63_3329	COG1309	transcriptional regulator
DR63_3331	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR63_3335	COG1132	(ABC) transporter
DR63_3340	COG1879	ABC-type sugar transport system periplasmic component
DR63_3342	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_3343	COG1063	alcohol dehydrogenase
DR63_3344	COG1070	Carbohydrate kinase
DR63_3345	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_3350	COG1120	ATPase activity
DR63_3358	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DR63_3359	COG4774	siderophore transport
DR63_3360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DR63_3366	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DR63_3371	COG0400	carboxylic ester hydrolase activity
DR63_3377	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DR63_3380	COG2099	Precorrin-6x reductase
DR63_3382	COG1649	PFAM Uncharacterised BCR, COG1649
DR63_3383	COG2807	transmembrane transport
DR63_3384	COG1846	Transcriptional regulator
DR63_3385	COG0625	glutathione transferase activity
DR63_3386	COG0583	DNA-binding transcription factor activity
DR63_3390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DR63_3391	COG2235	arginine
DR63_3394	COG1174	glycine betaine transport
DR63_3395	COG1125	glycine betaine transport
DR63_3396	COG1174	glycine betaine transport
DR63_3397	COG1732	Glycine betaine
DR63_3398	COG2226	methyltransferase
DR63_3399	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_34	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DR63_3402	COG0835	chemotaxis
DR63_3404	COG1917	Cupin 2, conserved barrel domain protein
DR63_3404	COG2207	Transcriptional regulator
DR63_3405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_341	COG1752	Esterase of the alpha-beta hydrolase superfamily
DR63_3412	COG1960	acyl-CoA dehydrogenase activity
DR63_3415	COG0492	ferredoxin-NADP+ reductase activity
DR63_342	COG0791	NLP P60 protein
DR63_3421	COG0753	catalase activity
DR63_3424	COG3039	Transposase
DR63_3425	COG3328	transposase activity
DR63_3426	COG3328	transposase activity
DR63_3427	COG3328	transposase activity
DR63_3428	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_3429	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_343	COG4172	Belongs to the ABC transporter superfamily
DR63_3430	COG1129	ABC transporter
DR63_3431	COG1879	ABC-type sugar transport system periplasmic component
DR63_3432	COG4214	carbohydrate transport
DR63_3434	COG4213	ABC transporter substrate-binding protein
DR63_3436	COG1609	Transcriptional regulator
DR63_3436	COG2207	Transcriptional regulator
DR63_3437	COG2017	converts alpha-aldose to the beta-anomer
DR63_3438	COG1454	alcohol dehydrogenase
DR63_344	COG4239	(ABC) transporter, permease
DR63_3442	COG0475	glutathione-regulated potassium exporter activity
DR63_3445	COG0835	chemotaxis
DR63_3447	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DR63_345	COG4174	ABC transporter (Permease)
DR63_3450	COG0745	RESPONSE REGULATOR receiver
DR63_3451	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DR63_3455	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DR63_3456	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR63_3457	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR63_3459	COG2894	cell division
DR63_346	COG4166	transmembrane transport
DR63_3460	COG1191	sigma factor activity
DR63_3462	COG1950	PFAM Membrane protein of
DR63_3463	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DR63_3468	COG2070	2-Nitropropane dioxygenase
DR63_3475	COG1522	sequence-specific DNA binding
DR63_3477	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DR63_3481	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DR63_3482	COG2823	Periplasmic or secreted lipoprotein
DR63_3483	COG4654	Cytochrome c, class I
DR63_3487	COG3436	PFAM IS66 Orf2 family protein
DR63_3488	COG4372	Transposase
DR63_349	COG0243	molybdopterin cofactor binding
DR63_3495	COG1476	TRANSCRIPTIONal
DR63_3500	COG3328	transposase activity
DR63_3501	COG1113	amino acid transport
DR63_3507	COG2084	Dehydrogenase
DR63_3508	COG1280	lysine exporter protein (LysE YggA)
DR63_3509	COG2814	Major facilitator Superfamily
DR63_351	COG0024	Methionine aminopeptidase
DR63_3510	COG0583	DNA-binding transcription factor activity
DR63_3516	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DR63_3518	COG1881	PFAM PEBP family protein
DR63_3519	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DR63_3520	COG0280	phosphate acetyltransferase
DR63_3520	COG0281	malic enzyme
DR63_3524	COG1522	sequence-specific DNA binding
DR63_3528	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DR63_3529	COG2151	metal-sulfur cluster biosynthetic enzyme
DR63_3530	COG3396	Phenylacetate-CoA oxygenase
DR63_3531	COG3460	Phenylacetate-CoA oxygenase
DR63_3532	COG3396	Phenylacetate-CoA oxygenase
DR63_354	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DR63_3540	COG4372	Transposase
DR63_3541	COG3436	PFAM IS66 Orf2 family protein
DR63_3548	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DR63_355	COG2895	sulfate adenylyltransferase (ATP) activity
DR63_3556	COG0514	ATP-dependent DNA helicase (RecQ)
DR63_3558	COG0049	tRNA binding
DR63_3559	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DR63_3573	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DR63_358	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DR63_3583	COG0201	protein transport
DR63_3592	COG4232	protein-disulfide reductase activity
DR63_3596	COG1333	cytochrome c biogenesis protein
DR63_3597	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DR63_3598	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DR63_3599	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DR63_36	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR63_361	COG3958	Transketolase
DR63_3610	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DR63_3613	COG0395	ABC-type sugar transport system, permease component
DR63_3615	COG0584	glycerophosphoryl diester phosphodiesterase
DR63_3618	COG0067	glutamate synthase
DR63_3618	COG0070	glutamate synthase
DR63_3618	COG0069	glutamate synthase activity
DR63_362	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DR63_3620	COG1115	amino acid carrier protein
DR63_3622	COG4178	(ABC) transporter
DR63_3627	COG1127	ABC transporter
DR63_3628	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DR63_3629	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DR63_3633	COG1131	(ABC) transporter
DR63_3634	COG0842	Transport permease protein
DR63_3638	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DR63_3639	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DR63_3641	COG2095	MarC family integral membrane protein
DR63_3642	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DR63_3651	COG0805	protein transport
DR63_3652	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR63_3653	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DR63_3654	COG0723	plastoquinol--plastocyanin reductase activity
DR63_3655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DR63_3656	COG2857	Cytochrome c1
DR63_3657	COG0625	glutathione transferase activity
DR63_3658	COG2969	positive regulation of protein catabolic process
DR63_3683	COG0308	aminopeptidase N
DR63_3692	COG0443	Heat shock 70 kDa protein
DR63_3693	COG1278	Cold shock
DR63_3694	COG0531	amino acid
DR63_3695	COG3384	dioxygenase
DR63_3697	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DR63_3698	COG2890	protein-(glutamine-N5) methyltransferase activity
DR63_3702	COG0006	proline dipeptidase activity
DR63_3703	COG1335	isochorismatase
DR63_3705	COG0488	(ABC) transporter
DR63_3709	COG0012	GTP binding
DR63_371	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_3712	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DR63_3713	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DR63_3716	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DR63_372	COG0529	Catalyzes the synthesis of activated sulfate
DR63_372	COG2895	sulfate adenylyltransferase (ATP) activity
DR63_3720	COG0512	Glutamine amidotransferase of anthranilate synthase
DR63_3722	COG0546	phosphoglycolate phosphatase activity
DR63_3724	COG2967	ApaG domain
DR63_3726	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DR63_3728	COG2050	protein possibly involved in aromatic compounds catabolism
DR63_3729	COG1024	Enoyl-CoA hydratase
DR63_373	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR63_3730	COG0183	Belongs to the thiolase family
DR63_3732	COG1024	Enoyl-CoA hydratase
DR63_3740	COG0789	Transcriptional regulator
DR63_3742	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DR63_3743	COG0667	Aldo Keto reductase
DR63_3744	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_3746	COG0556	nucleotide-excision repair
DR63_3748	COG4633	Protein conserved in bacteria
DR63_3751	COG3193	protein, possibly involved in utilization of glycolate and propanediol
DR63_3760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DR63_3767	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DR63_3769	COG0582	viral genome integration into host DNA
DR63_3776	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DR63_379	COG0527	aspartate kinase activity
DR63_3791	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DR63_3796	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DR63_3799	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DR63_380	COG0037	tRNA processing
DR63_3811	COG0583	DNA-binding transcription factor activity
DR63_3812	COG1741	Belongs to the pirin family
DR63_3814	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR63_3817	COG1796	DNA polymerase
DR63_3817	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DR63_3825	COG0840	transmembrane signaling receptor activity
DR63_3826	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR63_3827	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR63_3829	COG1177	transmembrane transport
DR63_3830	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR63_3831	COG3842	ATPase activity
DR63_3834	COG0174	glutamine synthetase
DR63_3835	COG0519	Catalyzes the synthesis of GMP from XMP
DR63_3835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DR63_3838	COG1012	belongs to the aldehyde dehydrogenase family
DR63_3839	COG0010	Belongs to the arginase family
DR63_3841	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DR63_3847	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DR63_385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DR63_3850	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_3853	COG3634	alkyl hydroperoxide reductase activity
DR63_3854	COG0450	alkyl hydroperoxide reductase
DR63_3857	COG0778	Nitroreductase
DR63_3858	COG2308	Evidence 4 Homologs of previously reported genes of
DR63_3864	COG1305	Transglutaminase-like
DR63_3868	COG1289	transmembrane transporter activity
DR63_387	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DR63_3871	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DR63_3872	COG0028	Belongs to the TPP enzyme family
DR63_3872	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DR63_388	COG1045	serine acetyltransferase
DR63_3887	COG3501	Rhs element vgr protein
DR63_3888	COG3501	Rhs element vgr protein
DR63_3902	COG2814	Major facilitator Superfamily
DR63_3905	COG1566	PFAM secretion protein HlyD family protein
DR63_3906	COG1621	beta-fructofuranosidase activity
DR63_3914	COG0446	pyridine nucleotide-disulphide oxidoreductase
DR63_3914	COG1902	pentaerythritol trinitrate reductase activity
DR63_3915	COG2181	nitrate reductase activity
DR63_3915	COG0247	lactate metabolic process
DR63_3916	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DR63_3920	COG2113	Glycine betaine
DR63_3923	COG0583	DNA-binding transcription factor activity
DR63_3924	COG3119	arylsulfatase activity
DR63_3931	COG3246	L-lysine catabolic process to acetate
DR63_3932	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR63_3944	COG0410	ABC transporter
DR63_3949	COG1021	2,3-dihydroxybenzoate-AMP ligase
DR63_395	COG2963	transposase activity
DR63_3951	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_3951	COG2226	methyltransferase
DR63_3951	COG3433	isochorismatase activity
DR63_3952	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_3952	COG2226	methyltransferase
DR63_3952	COG3433	isochorismatase activity
DR63_3955	COG1132	(ABC) transporter
DR63_3961	COG3284	Transcriptional regulator
DR63_3964	COG2252	PERMEase
DR63_3971	COG0330	HflC and HflK could
DR63_3974	COG1960	acyl-CoA dehydrogenase activity
DR63_3975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DR63_3978	COG1024	Enoyl-CoA hydratase
DR63_3979	COG1024	Enoyl-CoA hydratase
DR63_3980	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_3981	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_3984	COG1538	Outer membrane efflux protein
DR63_3986	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR63_3989	COG2066	Belongs to the glutaminase family
DR63_3993	COG2066	Belongs to the glutaminase family
DR63_3994	COG0745	RESPONSE REGULATOR receiver
DR63_3995	COG2205	protein histidine kinase activity
DR63_40	COG2855	membrane
DR63_4010	COG0642	Histidine kinase
DR63_4015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DR63_4022	COG3214	Protein conserved in bacteria
DR63_4023	COG0477	Major facilitator Superfamily
DR63_4024	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DR63_4031	COG2207	Transcriptional regulator
DR63_4036	COG2205	protein histidine kinase activity
DR63_4037	COG0745	RESPONSE REGULATOR receiver
DR63_4040	COG1846	Transcriptional regulator
DR63_4043	COG1012	belongs to the aldehyde dehydrogenase family
DR63_4044	COG3384	dioxygenase
DR63_4046	COG3971	2-oxopent-4-enoate hydratase activity
DR63_4049	COG3842	ATPase activity
DR63_4051	COG1840	ABC-type Fe3 transport system, periplasmic component
DR63_4053	COG0642	Histidine kinase
DR63_4054	COG3217	Mosc domain protein beta barrel domain protein
DR63_4054	COG0633	Ferredoxin
DR63_4056	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_4058	COG1024	Enoyl-CoA hydratase
DR63_4059	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DR63_4061	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DR63_4062	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DR63_4065	COG2192	nodulation
DR63_4067	COG2850	peptidyl-arginine hydroxylation
DR63_4070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DR63_4071	COG3128	pkhd-type hydroxylase
DR63_4076	COG1309	transcriptional regulator
DR63_4078	COG1902	pentaerythritol trinitrate reductase activity
DR63_4079	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DR63_4080	COG0454	-acetyltransferase
DR63_4083	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4090	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_4095	COG2197	response regulator
DR63_4097	COG0825	malonyl-CoA metabolic process
DR63_41	COG0038	chloride channel
DR63_4101	COG2070	2-Nitropropane dioxygenase
DR63_4101	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DR63_4102	COG4221	oxidoreductase activity
DR63_4102	COG3321	synthase
DR63_4102	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4102	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_4103	COG3321	synthase
DR63_4103	COG0300	oxidoreductase activity
DR63_4103	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_4103	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4103	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_4104	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_4105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DR63_4106	COG3425	synthase
DR63_4107	COG1024	Enoyl-CoA hydratase
DR63_4108	COG1024	Enoyl-CoA hydratase
DR63_4109	COG4221	oxidoreductase activity
DR63_4109	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_4109	COG3321	synthase
DR63_4109	COG0300	oxidoreductase activity
DR63_4110	COG4221	oxidoreductase activity
DR63_4110	COG4221	oxidoreductase activity
DR63_4110	COG0300	oxidoreductase activity
DR63_4110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_4110	COG3321	synthase
DR63_4110	COG3321	synthase
DR63_4110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_4110	COG0300	oxidoreductase activity
DR63_4111	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_4111	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_4111	COG3321	synthase
DR63_4111	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_4111	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4112	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4112	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_4112	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_4112	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_4112	COG3321	synthase
DR63_4121	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR63_4130	COG0583	DNA-binding transcription factor activity
DR63_4132	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_4134	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DR63_4135	COG2508	Transcriptional regulator
DR63_4136	COG0402	S-adenosylhomocysteine deaminase activity
DR63_4138	COG1858	cytochrome C peroxidase
DR63_4139	COG3511	phospholipase C
DR63_4156	COG2217	Heavy metal translocating P-type atpase
DR63_4157	COG2010	Cytochrome c
DR63_4163	COG0583	DNA-binding transcription factor activity
DR63_4166	COG0789	Transcriptional regulator
DR63_4169	COG1129	ABC transporter
DR63_4170	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_4172	COG2721	sulfolactate sulfo-lyase activity
DR63_4175	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4177	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4182	COG1272	protein, Hemolysin III
DR63_4184	COG1522	sequence-specific DNA binding
DR63_4186	COG1448	Aminotransferase
DR63_419	COG2850	peptidyl-arginine hydroxylation
DR63_4192	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR63_4192	COG4191	Histidine kinase
DR63_4193	COG2201	protein-glutamate methylesterase activity
DR63_4195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DR63_4196	COG2373	Large extracellular alpha-helical protein
DR63_42	COG1309	transcriptional regulator
DR63_420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DR63_4200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DR63_4200	COG2885	chlorophyll binding
DR63_4201	COG3291	Pkd domain containing protein
DR63_4203	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DR63_421	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DR63_4212	COG0589	response to stress
DR63_4217	COG4221	oxidoreductase activity
DR63_4219	COG1113	amino acid transport
DR63_422	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR63_4221	COG2916	Histone family protein nucleoid-structuring protein H-NS
DR63_4224	COG1957	nucleoside hydrolase
DR63_4225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR63_4229	COG0583	DNA-binding transcription factor activity
DR63_4237	COG0583	DNA-binding transcription factor activity
DR63_424	COG0180	Tryptophanyl-tRNA synthetase
DR63_4243	COG1012	belongs to the aldehyde dehydrogenase family
DR63_4244	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DR63_4245	COG0531	amino acid
DR63_4248	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_4249	COG3501	Rhs element vgr protein
DR63_425	COG1994	Peptidase M50
DR63_4252	COG3328	transposase activity
DR63_4256	COG1902	pentaerythritol trinitrate reductase activity
DR63_4259	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_426	COG0009	L-threonylcarbamoyladenylate synthase
DR63_4263	COG0517	IMP dehydrogenase activity
DR63_4263	COG0516	GMP reductase activity
DR63_4265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DR63_4268	COG2197	response regulator
DR63_4269	COG1285	pathogenesis
DR63_427	COG0613	PHP domain protein
DR63_4270	COG1408	metallophosphoesterase
DR63_4273	COG1414	Transcriptional regulator
DR63_4275	COG2146	nitrite reductase [NAD(P)H] activity
DR63_428	COG0596	Alpha beta hydrolase
DR63_4281	COG1414	Transcriptional regulator
DR63_4282	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4283	COG0028	Belongs to the TPP enzyme family
DR63_4288	COG0477	Major facilitator Superfamily
DR63_429	COG2833	Protein of unknown function (DUF455)
DR63_4290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DR63_4290	COG2885	chlorophyll binding
DR63_4292	COG0154	amidase activity
DR63_4293	COG1522	sequence-specific DNA binding
DR63_4300	COG3634	alkyl hydroperoxide reductase activity
DR63_4301	COG0154	amidase activity
DR63_4303	COG0596	Alpha beta hydrolase
DR63_4308	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DR63_431	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DR63_4313	COG0840	transmembrane signaling receptor activity
DR63_4316	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR63_4317	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DR63_4323	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_4328	COG0583	DNA-binding transcription factor activity
DR63_433	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DR63_4331	COG4172	Belongs to the ABC transporter superfamily
DR63_4333	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DR63_4334	COG0601	transmembrane transport
DR63_4339	COG3501	Rhs element vgr protein
DR63_4341	COG3209	COG3209 Rhs family protein
DR63_4349	COG2140	Oxalate decarboxylase
DR63_435	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DR63_4350	COG1914	H( )-stimulated, divalent metal cation uptake system
DR63_4351	COG4682	membrane
DR63_4352	COG3781	membrane
DR63_4353	COG0243	molybdopterin cofactor binding
DR63_4354	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR63_4359	COG1404	Belongs to the peptidase S8 family
DR63_4364	COG2259	Doxx family
DR63_4367	COG4215	(ABC) transporter
DR63_4368	COG4160	amino acid transport
DR63_437	COG2267	carboxylic ester hydrolase activity
DR63_4375	COG3275	phosphorelay sensor kinase activity
DR63_4378	COG0500	methyltransferase
DR63_438	COG2333	competence protein COMEC
DR63_438	COG0658	competence protein
DR63_4382	COG0583	DNA-binding transcription factor activity
DR63_4383	COG0387	Pfam Sodium calcium exchanger
DR63_4387	COG0179	Fumarylacetoacetate (FAA) hydrolase
DR63_439	COG0084	hydrolase, TatD family'
DR63_4392	COG2353	YceI-like domain
DR63_4394	COG1595	DNA-templated transcription, initiation
DR63_4395	COG3712	iron ion homeostasis
DR63_4396	COG4774	siderophore transport
DR63_44	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR63_4421	COG0489	protein tyrosine kinase activity
DR63_4427	COG4695	Portal protein
DR63_443	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DR63_444	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DR63_4460	COG0443	Heat shock 70 kDa protein
DR63_4461	COG0443	Heat shock 70 kDa protein
DR63_4463	COG4274	PFAM GYD family protein
DR63_4468	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DR63_4469	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DR63_447	COG2975	iron-sulfur cluster assembly
DR63_4471	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DR63_4475	COG0351	phosphomethylpyrimidine kinase
DR63_4485	COG0842	Transport permease protein
DR63_4486	COG0842	Transport permease protein
DR63_4487	COG1131	(ABC) transporter
DR63_4488	COG1131	(ABC) transporter
DR63_4489	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR63_4492	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR63_4493	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR63_4494	COG1538	Outer membrane efflux protein
DR63_4495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DR63_4498	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DR63_4499	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DR63_4499	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DR63_4507	COG1902	pentaerythritol trinitrate reductase activity
DR63_4507	COG0446	pyridine nucleotide-disulphide oxidoreductase
DR63_4508	COG1695	Transcriptional regulator
DR63_451	COG0316	Belongs to the HesB IscA family
DR63_4514	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DR63_4515	COG0649	NAD binding
DR63_4516	COG0651	ATP synthesis coupled electron transport
DR63_4518	COG0650	Formate hydrogenlyase subunit 4
DR63_4519	COG0651	ATP synthesis coupled electron transport
DR63_452	COG0822	iron-sulfur transferase activity
DR63_4523	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DR63_4527	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DR63_4528	COG2181	nitrate reductase activity
DR63_4529	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DR63_453	COG1104	cysteine desulfurase activity
DR63_4530	COG1140	nitrate reductase beta subunit
DR63_4531	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DR63_4532	COG3851	Histidine kinase
DR63_4535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DR63_4541	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DR63_455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DR63_4550	COG0475	glutathione-regulated potassium exporter activity
DR63_4558	COG0477	Major facilitator Superfamily
DR63_4559	COG1414	Transcriptional regulator
DR63_4562	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DR63_4572	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DR63_4575	COG0540	Belongs to the ATCase OTCase family
DR63_4579	COG1335	isochorismatase
DR63_4583	COG0840	transmembrane signaling receptor activity
DR63_4586	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4587	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DR63_4587	COG4651	solute:proton antiporter activity
DR63_459	COG1414	Transcriptional regulator
DR63_4592	COG0745	RESPONSE REGULATOR receiver
DR63_4593	COG0642	Histidine kinase
DR63_4598	COG0586	Pfam SNARE associated Golgi protein
DR63_4600	COG2223	nitrite transmembrane transporter activity
DR63_4605	COG1063	alcohol dehydrogenase
DR63_4606	COG3842	ATPase activity
DR63_4608	COG1070	Carbohydrate kinase
DR63_4610	COG0243	molybdopterin cofactor binding
DR63_4611	COG2146	nitrite reductase [NAD(P)H] activity
DR63_4612	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DR63_4615	COG3707	response regulator
DR63_4616	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DR63_4616	COG1116	anion transmembrane transporter activity
DR63_462	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DR63_4620	COG0477	Major facilitator Superfamily
DR63_4621	COG0583	DNA-binding transcription factor activity
DR63_4624	COG0583	DNA-binding transcription factor activity
DR63_4625	COG1794	racemase activity, acting on amino acids and derivatives
DR63_4626	COG0583	DNA-binding transcription factor activity
DR63_4627	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_4628	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR63_463	COG0508	dehydrogenase complex catalyzes the overall conversion of
DR63_4634	COG1739	Uncharacterized protein family UPF0029
DR63_4636	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DR63_464	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DR63_4649	COG1201	RNA secondary structure unwinding
DR63_4650	COG0531	amino acid
DR63_4651	COG4251	negative regulation of phosphorylation
DR63_4651	COG3706	GGDEF domain
DR63_4651	COG2203	Gaf domain
DR63_4651	COG5001	Diguanylate cyclase
DR63_4652	COG3795	YCII-related domain
DR63_4653	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DR63_4655	COG5001	Diguanylate cyclase
DR63_4655	COG2203	Gaf domain
DR63_4655	COG3706	GGDEF domain
DR63_4655	COG4251	negative regulation of phosphorylation
DR63_4657	COG0583	DNA-binding transcription factor activity
DR63_4658	COG3485	protocatechuate 3,4-dioxygenase
DR63_4659	COG3485	protocatechuate 3,4-dioxygenase
DR63_466	COG4566	intracellular signal transduction
DR63_4662	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DR63_4663	COG0601	transmembrane transport
DR63_4665	COG4172	Belongs to the ABC transporter superfamily
DR63_4666	COG1446	asparaginase
DR63_4668	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DR63_4678	COG0546	phosphoglycolate phosphatase activity
DR63_468	COG0339	signal peptide processing
DR63_4680	COG2188	Transcriptional regulator
DR63_4684	COG1858	cytochrome C peroxidase
DR63_4685	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DR63_469	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DR63_4690	COG2391	methyltransferase activity
DR63_4691	COG0640	Transcriptional regulator
DR63_4693	COG1505	serine-type exopeptidase activity
DR63_4694	COG3328	transposase activity
DR63_4695	COG1566	PFAM secretion protein HlyD family protein
DR63_4698	COG2814	Major facilitator Superfamily
DR63_47	COG3655	Transcriptional regulator
DR63_470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DR63_4705	COG2814	Major facilitator Superfamily
DR63_473	COG2223	nitrite transmembrane transporter activity
DR63_474	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DR63_475	COG1140	nitrate reductase beta subunit
DR63_476	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DR63_4761	COG0477	Major facilitator Superfamily
DR63_4763	COG0784	Response regulator, receiver
DR63_4764	COG4251	negative regulation of phosphorylation
DR63_477	COG2181	nitrate reductase activity
DR63_4770	COG1278	Cold shock
DR63_4776	COG1760	l-serine dehydratase
DR63_4785	COG1609	Transcriptional regulator
DR63_479	COG2197	response regulator
DR63_4790	COG2186	Transcriptional regulator
DR63_4791	COG2084	Dehydrogenase
DR63_4792	COG3395	kinase activity
DR63_4793	COG0235	Class ii aldolase
DR63_4794	COG2271	Major facilitator Superfamily
DR63_4795	COG3622	Belongs to the hyi family
DR63_4796	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_4802	COG4175	Glycine betaine
DR63_4808	COG0640	Transcriptional regulator
DR63_4811	COG0798	PFAM Bile acid sodium symporter
DR63_4820	COG5295	Hep Hag repeat protein
DR63_4826	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DR63_4827	COG1960	acyl-CoA dehydrogenase activity
DR63_483	COG3852	Histidine kinase
DR63_4831	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_4833	COG0058	SHG alpha-glucan phosphorylase activity
DR63_4842	COG3501	Rhs element vgr protein
DR63_4846	COG0022	dehydrogenase e1 component
DR63_4846	COG0508	dehydrogenase complex catalyzes the overall conversion of
DR63_4847	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DR63_4848	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DR63_4850	COG3876	Protein conserved in bacteria
DR63_4853	COG0686	Belongs to the AlaDH PNT family
DR63_4859	COG0459	protein refolding
DR63_486	COG1058	Belongs to the CinA family
DR63_486	COG1546	Belongs to the CinA family
DR63_4864	COG2271	Major facilitator Superfamily
DR63_4866	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DR63_4866	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DR63_4867	COG1105	Belongs to the carbohydrate kinase PfkB family
DR63_4868	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DR63_4868	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DR63_4869	COG1609	Transcriptional regulator
DR63_4871	COG0745	RESPONSE REGULATOR receiver
DR63_4876	COG1012	belongs to the aldehyde dehydrogenase family
DR63_4877	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR63_4879	COG0583	DNA-binding transcription factor activity
DR63_4881	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR63_4884	COG1349	DNA-binding transcription factor activity
DR63_4889	COG5441	Belongs to the UPF0261 family
DR63_4890	COG5564	TIM-barrel signal transduction protein
DR63_4896	COG5295	Hep Hag repeat protein
DR63_4897	COG3023	N-Acetylmuramoyl-L-alanine amidase
DR63_4899	COG5295	Hep Hag repeat protein
DR63_490	COG1643	Atp-dependent helicase
DR63_4902	COG0745	RESPONSE REGULATOR receiver
DR63_491	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DR63_491	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DR63_4928	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR63_493	COG0477	Major facilitator Superfamily
DR63_4931	COG2916	Histone family protein nucleoid-structuring protein H-NS
DR63_4938	COG4790	Type iii secretion
DR63_4941	COG1157	protein secretion by the type III secretion system
DR63_4943	COG4789	Type iii secretion
DR63_495	COG1960	acyl-CoA dehydrogenase activity
DR63_4958	COG0477	Major facilitator Superfamily
DR63_496	COG0583	DNA-binding transcription factor activity
DR63_4964	COG1280	lysine exporter protein (LysE YggA)
DR63_4965	COG1522	sequence-specific DNA binding
DR63_4967	COG0306	phosphate transporter
DR63_4970	COG3916	Acyl-homoserine-lactone synthase
DR63_4972	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DR63_4974	COG4521	taurine ABC transporter
DR63_4975	COG2175	clavaminate synthase activity
DR63_4977	COG2194	sulfuric ester hydrolase activity
DR63_4978	COG1215	transferase activity, transferring glycosyl groups
DR63_4982	COG0457	Tetratricopeptide repeat
DR63_4984	COG1215	transferase activity, transferring glycosyl groups
DR63_4987	COG1067	ATP-dependent peptidase activity
DR63_500	COG0174	glutamine synthetase
DR63_501	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DR63_5012	COG2207	Transcriptional regulator
DR63_5018	COG4794	Type iii secretion
DR63_5023	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR63_503	COG0402	S-adenosylhomocysteine deaminase activity
DR63_5034	COG3293	Transposase
DR63_5037	COG2814	Major facilitator Superfamily
DR63_5039	COG4191	Histidine kinase
DR63_5041	COG2204	response regulator
DR63_5056	COG2755	lipolytic protein G-D-S-L family
DR63_5056	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DR63_5057	COG3276	selenocysteine insertion sequence binding
DR63_506	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DR63_5060	COG2864	formate dehydrogenase
DR63_5061	COG0437	4 iron, 4 sulfur cluster binding
DR63_5062	COG3383	formate dehydrogenase (NAD+) activity
DR63_5062	COG0243	molybdopterin cofactor binding
DR63_5063	COG3383	formate dehydrogenase (NAD+) activity
DR63_5063	COG0243	molybdopterin cofactor binding
DR63_5067	COG1295	ribonuclease BN
DR63_5068	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_5071	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DR63_5071	COG2755	lipolytic protein G-D-S-L family
DR63_5072	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DR63_5075	COG0438	transferase activity, transferring glycosyl groups
DR63_5078	COG2755	lipolytic protein G-D-S-L family
DR63_5078	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DR63_5079	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DR63_5081	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR63_5086	COG0285	dihydrofolate synthase activity
DR63_5087	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DR63_5090	COG0133	tryptophan synthase activity
DR63_5091	COG0135	phosphoribosylanthranilate isomerase activity
DR63_5099	COG1522	sequence-specific DNA binding
DR63_5104	COG0372	Belongs to the citrate synthase family
DR63_5105	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DR63_5106	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DR63_5107	COG1053	succinate dehydrogenase
DR63_5109	COG2009	succinate dehydrogenase
DR63_5110	COG2188	Transcriptional regulator
DR63_5115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DR63_5116	COG3258	Cytochrome c
DR63_5117	COG2010	Cytochrome c
DR63_512	COG0529	Catalyzes the synthesis of activated sulfate
DR63_5124	COG1177	transmembrane transport
DR63_5125	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR63_5127	COG3842	ATPase activity
DR63_513	COG0415	Belongs to the DNA photolyase family
DR63_5131	COG4771	TonB-dependent receptor
DR63_5133	COG3038	cytochrome b561
DR63_5140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DR63_5141	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DR63_5144	COG3328	transposase activity
DR63_5147	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DR63_5151	COG2081	HI0933 family
DR63_5155	COG0142	geranyltranstransferase activity
DR63_5159	COG0412	Dienelactone hydrolase
DR63_516	COG2151	metal-sulfur cluster biosynthetic enzyme
DR63_5161	COG1252	NADH dehydrogenase
DR63_5163	COG1611	Belongs to the LOG family
DR63_5165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DR63_5169	COG1846	Transcriptional regulator
DR63_5170	COG1764	response to oxidative stress
DR63_5174	COG0725	ABC transporter, periplasmic molybdate-binding protein
DR63_5175	COG4149	molybdate abc transporter
DR63_5180	COG0583	DNA-binding transcription factor activity
DR63_5183	COG1253	flavin adenine dinucleotide binding
DR63_5184	COG0352	thiamine-phosphate diphosphorylase activity
DR63_5185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DR63_5188	COG1304	FMN binding
DR63_5193	COG3293	Transposase
DR63_5200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DR63_5201	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DR63_5205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_5209	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DR63_5210	COG5654	RES domain protein
DR63_5211	COG5642	Protein of unknown function (DUF2384)
DR63_5215	COG0438	transferase activity, transferring glycosyl groups
DR63_5216	COG0438	transferase activity, transferring glycosyl groups
DR63_5219	COG0463	Glycosyl transferase, family 2
DR63_5220	COG0489	protein tyrosine kinase activity
DR63_5220	COG3206	protein involved in exopolysaccharide biosynthesis
DR63_5224	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DR63_5228	COG0247	lactate metabolic process
DR63_5229	COG1592	Rubrerythrin
DR63_5230	COG3023	N-Acetylmuramoyl-L-alanine amidase
DR63_5231	COG4941	Belongs to the sigma-70 factor family
DR63_5233	COG3795	YCII-related domain
DR63_5234	COG3795	YCII-related domain
DR63_5238	COG0628	permease
DR63_5243	COG2130	NADP-dependent
DR63_5246	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_5250	COG0583	DNA-binding transcription factor activity
DR63_5253	COG2837	iron assimilation
DR63_5254	COG5265	(ABC) transporter
DR63_5256	COG4977	sequence-specific DNA binding
DR63_5262	COG0038	chloride channel
DR63_5269	COG0840	transmembrane signaling receptor activity
DR63_527	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DR63_5270	COG0642	Histidine kinase
DR63_5272	COG1012	belongs to the aldehyde dehydrogenase family
DR63_5274	COG0025	NhaP-type Na H and K H
DR63_5275	COG2733	membrane
DR63_5277	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DR63_5280	COG2146	nitrite reductase [NAD(P)H] activity
DR63_5281	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DR63_5282	COG4638	Rieske (2fe-2S)
DR63_5288	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DR63_529	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DR63_5292	COG0446	pyridine nucleotide-disulphide oxidoreductase
DR63_5292	COG1902	pentaerythritol trinitrate reductase activity
DR63_5295	COG0583	DNA-binding transcription factor activity
DR63_5296	COG4638	Rieske (2fe-2S)
DR63_5297	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DR63_5298	COG0543	2 iron, 2 sulfur cluster binding
DR63_5298	COG0633	Ferredoxin
DR63_5299	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_53	COG1177	transmembrane transport
DR63_530	COG0840	transmembrane signaling receptor activity
DR63_5302	COG1335	isochorismatase
DR63_5306	COG0833	amino acid
DR63_5308	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DR63_5309	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_5310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DR63_5316	COG1611	Belongs to the LOG family
DR63_532	COG0719	Fe-S assembly protein
DR63_5320	COG2895	sulfate adenylyltransferase (ATP) activity
DR63_5320	COG0529	Catalyzes the synthesis of activated sulfate
DR63_5321	COG0840	transmembrane signaling receptor activity
DR63_5325	COG1136	(ABC) transporter
DR63_5328	COG0589	response to stress
DR63_533	COG0396	ATPase activity
DR63_5331	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR63_5332	COG1129	ABC transporter
DR63_5332	COG0842	Transport permease protein
DR63_5333	COG0842	Transport permease protein
DR63_5335	COG3293	Transposase
DR63_5336	COG2124	cytochrome p450
DR63_5344	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DR63_5346	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DR63_5346	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DR63_5348	COG0356	it plays a direct role in the translocation of protons across the membrane
DR63_535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DR63_5351	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DR63_5353	COG3243	poly(R)-hydroxyalkanoic acid synthase
DR63_5355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DR63_5357	COG2823	Periplasmic or secreted lipoprotein
DR63_5358	COG0295	cytidine deaminase activity
DR63_536	COG0822	iron-sulfur transferase activity
DR63_5362	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DR63_5363	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DR63_5364	COG1017	nitric oxide dioxygenase activity
DR63_5364	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DR63_5365	COG0625	glutathione transferase activity
DR63_537	COG2151	metal-sulfur cluster biosynthetic enzyme
DR63_5370	COG2267	carboxylic ester hydrolase activity
DR63_5371	COG3706	GGDEF domain
DR63_5371	COG0745	RESPONSE REGULATOR receiver
DR63_5383	COG1230	cation diffusion facilitator family transporter
DR63_539	COG1959	2 iron, 2 sulfur cluster binding
DR63_5392	COG1573	uracil-dna glycosylase
DR63_5394	COG1404	Belongs to the peptidase S8 family
DR63_5397	COG0642	Histidine kinase
DR63_54	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR63_5405	COG2963	transposase activity
DR63_5408	COG3189	MarR family transcriptional regulator
DR63_5410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DR63_5416	COG3328	transposase activity
DR63_5420	COG3293	Transposase
DR63_5421	COG2271	Major facilitator Superfamily
DR63_5422	COG3265	gluconokinase activity
DR63_5423	COG0583	DNA-binding transcription factor activity
DR63_5424	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_5425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DR63_5431	COG1215	transferase activity, transferring glycosyl groups
DR63_544	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DR63_5441	COG0583	DNA-binding transcription factor activity
DR63_5442	COG2814	Major facilitator Superfamily
DR63_5444	COG1012	belongs to the aldehyde dehydrogenase family
DR63_5450	COG4191	Histidine kinase
DR63_5450	COG2205	protein histidine kinase activity
DR63_5450	COG0745	RESPONSE REGULATOR receiver
DR63_5454	COG0154	amidase activity
DR63_5455	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_5457	COG4566	intracellular signal transduction
DR63_5459	COG0583	DNA-binding transcription factor activity
DR63_546	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR63_5460	COG1253	flavin adenine dinucleotide binding
DR63_5466	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DR63_5468	COG1960	acyl-CoA dehydrogenase activity
DR63_5471	COG1720	tRNA m6t6A37 methyltransferase activity
DR63_5473	COG2226	methyltransferase
DR63_5474	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DR63_5475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DR63_5479	COG0477	Major facilitator Superfamily
DR63_548	COG0625	glutathione transferase activity
DR63_5482	COG1960	acyl-CoA dehydrogenase activity
DR63_5483	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_5484	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DR63_5485	COG1960	acyl-CoA dehydrogenase activity
DR63_5488	COG3246	L-lysine catabolic process to acetate
DR63_5489	COG1022	Amp-dependent synthetase and ligase
DR63_55	COG3842	ATPase activity
DR63_5501	COG0494	nUDIX hydrolase
DR63_5502	COG0546	phosphoglycolate phosphatase activity
DR63_5505	COG3328	transposase activity
DR63_5507	COG3209	COG3209 Rhs family protein
DR63_5509	COG3501	Rhs element vgr protein
DR63_5528	COG0583	DNA-binding transcription factor activity
DR63_5531	COG0583	DNA-binding transcription factor activity
DR63_5533	COG0477	Major facilitator Superfamily
DR63_5535	COG1304	FMN binding
DR63_554	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DR63_5542	COG0367	asparagine synthase
DR63_5546	COG3537	Alpha-1,2-mannosidase
DR63_5549	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_5557	COG0583	DNA-binding transcription factor activity
DR63_5558	COG1473	amidohydrolase
DR63_5560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_5561	COG0513	Belongs to the DEAD box helicase family
DR63_5566	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR63_5567	COG1879	ABC-type sugar transport system periplasmic component
DR63_5568	COG3706	GGDEF domain
DR63_5568	COG4251	negative regulation of phosphorylation
DR63_5568	COG5001	Diguanylate cyclase
DR63_5568	COG2203	Gaf domain
DR63_557	COG4160	amino acid transport
DR63_5572	COG0318	PFAM AMP-dependent synthetase and ligase
DR63_5572	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR63_5572	COG3321	synthase
DR63_5572	COG0300	oxidoreductase activity
DR63_5572	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_5573	COG3835	regulator
DR63_5574	COG0469	pyruvate kinase activity
DR63_5575	COG1929	Belongs to the glycerate kinase type-1 family
DR63_5576	COG2271	Major facilitator Superfamily
DR63_558	COG4215	(ABC) transporter
DR63_5588	COG4786	Flagellar basal body rod
DR63_5590	COG1749	Flagellar hook protein flgE
DR63_5592	COG1558	bacterial-type flagellum-dependent cell motility
DR63_5593	COG1815	bacterial-type flagellum-dependent cell motility
DR63_5598	COG1191	sigma factor activity
DR63_56	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DR63_5603	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DR63_5607	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DR63_5608	COG1766	The M ring may be actively involved in energy transduction
DR63_5609	COG1677	Flagellar hook-basal body complex protein FliE
DR63_561	COG3394	polysaccharide catabolic process
DR63_5613	COG1987	bacterial-type flagellum assembly
DR63_5614	COG1684	flagellar biosynthetic protein fliR
DR63_5615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR63_5620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DR63_5621	COG0840	transmembrane signaling receptor activity
DR63_5624	COG0745	RESPONSE REGULATOR receiver
DR63_5626	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DR63_5627	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DR63_5629	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DR63_5630	COG2217	Heavy metal translocating P-type atpase
DR63_5634	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR63_5634	COG2205	protein histidine kinase activity
DR63_5637	COG2205	protein histidine kinase activity
DR63_5637	COG0784	Response regulator, receiver
DR63_564	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DR63_5649	COG3501	Rhs element vgr protein
DR63_565	COG0596	Alpha beta hydrolase
DR63_5661	COG3188	usher protein
DR63_5662	COG3121	Chaperone
DR63_5666	COG5295	Hep Hag repeat protein
DR63_567	COG3511	phospholipase C
DR63_5671	COG1538	Outer membrane efflux protein
DR63_5672	COG0583	DNA-binding transcription factor activity
DR63_5676	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_568	COG0683	leucine binding
DR63_5680	COG0432	Pfam Uncharacterised protein family UPF0047
DR63_5684	COG2963	transposase activity
DR63_569	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR63_5690	COG3501	Rhs element vgr protein
DR63_5692	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DR63_5697	COG3397	chitin binding
DR63_57	COG1914	H( )-stimulated, divalent metal cation uptake system
DR63_5708	COG0596	Alpha beta hydrolase
DR63_572	COG0438	transferase activity, transferring glycosyl groups
DR63_5722	COG2818	Glycosylase
DR63_5726	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DR63_5727	COG2916	Histone family protein nucleoid-structuring protein H-NS
DR63_5728	COG0438	transferase activity, transferring glycosyl groups
DR63_573	COG1132	(ABC) transporter
DR63_580	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DR63_585	COG2153	protein acetylation
DR63_587	COG0583	DNA-binding transcription factor activity
DR63_588	COG1956	GAF domain-containing protein
DR63_59	COG3047	cAMP biosynthetic process
DR63_590	COG3328	transposase activity
DR63_595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DR63_599	COG2204	response regulator
DR63_6	COG4263	nitrous-oxide reductase activity
DR63_60	COG2070	2-Nitropropane dioxygenase
DR63_600	COG1472	Belongs to the glycosyl hydrolase 3 family
DR63_602	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DR63_604	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DR63_605	COG0571	ribonuclease III activity
DR63_606	COG0681	Belongs to the peptidase S26 family
DR63_609	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR63_610	COG3026	antisigma factor binding
DR63_614	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DR63_62	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_621	COG1399	metal-binding, possibly nucleic acid-binding protein
DR63_626	COG0546	phosphoglycolate phosphatase activity
DR63_628	COG1530	ribonuclease E activity
DR63_629	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DR63_63	COG0488	(ABC) transporter
DR63_638	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DR63_639	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DR63_64	COG2982	Protein involved in outer membrane biogenesis
DR63_642	COG3045	CreA protein
DR63_644	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DR63_648	COG2501	S4 domain
DR63_649	COG0534	Mate efflux family protein
DR63_65	COG1122	ATPase activity
DR63_650	COG0114	fumarate hydratase activity
DR63_651	COG1607	acyl-coa hydrolase
DR63_652	COG0640	Transcriptional regulator
DR63_654	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DR63_658	COG2204	response regulator
DR63_659	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DR63_66	COG0390	transport system, permease component
DR63_660	COG0312	modulator of DNA gyrase
DR63_661	COG3028	Belongs to the UPF0307 family
DR63_662	COG0521	Mo-molybdopterin cofactor biosynthetic process
DR63_664	COG0501	Belongs to the peptidase M48B family
DR63_677	COG1522	sequence-specific DNA binding
DR63_679	COG1960	acyl-CoA dehydrogenase activity
DR63_68	COG0560	Phosphoserine phosphatase
DR63_682	COG1464	Belongs to the NlpA lipoprotein family
DR63_683	COG2011	ABC-type metal ion transport system permease component
DR63_685	COG2267	carboxylic ester hydrolase activity
DR63_686	COG0123	including yeast histone deacetylase and acetoin utilization protein
DR63_687	COG2951	lytic endotransglycosylase activity
DR63_69	COG0626	cystathionine gamma-synthase activity
DR63_691	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DR63_693	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DR63_698	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DR63_699	COG1605	Chorismate mutase
DR63_699	COG0077	Prephenate dehydratase
DR63_700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DR63_705	COG0546	phosphoglycolate phosphatase activity
DR63_706	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DR63_708	COG1910	domain protein
DR63_71	COG0183	Belongs to the thiolase family
DR63_711	COG3383	formate dehydrogenase (NAD+) activity
DR63_716	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DR63_720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DR63_721	COG2252	PERMEase
DR63_722	COG0402	S-adenosylhomocysteine deaminase activity
DR63_724	COG2119	membrane
DR63_726	COG0308	aminopeptidase N
DR63_728	COG0583	DNA-binding transcription factor activity
DR63_734	COG4772	TonB-dependent receptor
DR63_738	COG2176	DNA-directed DNA polymerase activity
DR63_739	COG1278	Cold shock
DR63_741	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR63_745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DR63_748	COG1561	YicC-like family, N-terminal region
DR63_75	COG1028	Short-chain dehydrogenase reductase Sdr
DR63_750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DR63_751	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DR63_757	COG0477	Major facilitator Superfamily
DR63_759	COG0859	PFAM glycosyl transferase family 9
DR63_76	COG0183	Belongs to the thiolase family
DR63_764	COG2894	cell division
DR63_77	COG3243	poly(R)-hydroxyalkanoic acid synthase
DR63_772	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DR63_773	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DR63_774	COG1674	ftsk spoiiie
DR63_775	COG0492	ferredoxin-NADP+ reductase activity
DR63_776	COG1193	negative regulation of DNA recombination
DR63_777	COG2860	membrane
DR63_778	COG3842	ATPase activity
DR63_779	COG0395	ABC-type sugar transport system, permease component
DR63_782	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DR63_784	COG0363	glucosamine-6-phosphate deaminase activity
DR63_786	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR63_788	COG1126	abc transporter atp-binding protein
DR63_789	COG2814	Major facilitator Superfamily
DR63_79	COG0564	pseudouridine synthase activity
DR63_794	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DR63_794	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DR63_800	COG2963	transposase activity
DR63_806	COG0436	Aminotransferase
DR63_81	COG1199	ATP-dependent helicase activity
DR63_813	COG0762	integral membrane protein
DR63_817	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DR63_826	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DR63_828	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DR63_832	COG0559	Belongs to the binding-protein-dependent transport system permease family
DR63_834	COG1129	ABC transporter
DR63_84	COG2183	response to ionizing radiation
DR63_845	COG0859	PFAM glycosyl transferase family 9
DR63_850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DR63_853	COG1215	transferase activity, transferring glycosyl groups
DR63_86	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DR63_868	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DR63_872	COG1773	rubredoxin
DR63_875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DR63_878	COG2963	transposase activity
DR63_884	COG3436	PFAM IS66 Orf2 family protein
DR63_885	COG4372	Transposase
DR63_887	COG4372	Transposase
DR63_888	COG3436	PFAM IS66 Orf2 family protein
DR63_889	COG4372	Transposase
DR63_89	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
DR63_890	COG3436	PFAM IS66 Orf2 family protein
DR63_893	COG0210	DNA helicase
DR63_9	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DR63_90	COG0330	HflC and HflK could
DR63_900	COG3436	PFAM IS66 Orf2 family protein
DR63_901	COG4372	Transposase
DR63_902	COG3436	PFAM IS66 Orf2 family protein
DR63_903	COG4372	Transposase
DR63_905	COG1733	regulation of RNA biosynthetic process
DR63_906	COG0604	alcohol dehydrogenase
DR63_91	COG0330	HflC and HflK could
DR63_916	COG1280	lysine exporter protein (LysE YggA)
DR63_919	COG0730	response to heat
DR63_92	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DR63_926	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DR63_928	COG1120	ATPase activity
DR63_929	COG4774	siderophore transport
DR63_932	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DR63_937	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DR63_938	COG0583	DNA-binding transcription factor activity
DR63_939	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DR63_940	COG0778	Nitroreductase
DR63_941	COG2814	Major facilitator Superfamily
DR63_945	COG2814	Major facilitator Superfamily
DR63_95	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DR63_953	COG1960	acyl-CoA dehydrogenase activity
DR63_954	COG0450	alkyl hydroperoxide reductase
DR63_966	COG4221	oxidoreductase activity
DR63_967	COG0824	Thioesterase
DR63_977	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DR63_982	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DR63_982	COG0517	IMP dehydrogenase activity
DR63_983	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DR63_984	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DR63_987	COG1045	serine acetyltransferase
DR63_988	COG3562	capsule polysaccharide
DR63_990	COG3206	protein involved in exopolysaccharide biosynthesis
DR63_990	COG0489	protein tyrosine kinase activity
DR63_991	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family