locus-tag	class	description
CCON33237_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CCON33237_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CCON33237_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCON33237_0004	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CCON33237_0007	ENOG4105BZE	flagellar hook protein, FlgE
CCON33237_0008	ENOG4105W00	Flagellar hook capping protein
CCON33237_0010	ENOG4105CI3	gtp-binding protein typa
CCON33237_0012	ENOG4105II7	pyrroline-5-carboxylate reductase
CCON33237_0015	ENOG4108J2R	molybdopterin oxidoreductase
CCON33237_0017	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CCON33237_0023	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CCON33237_0024	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
CCON33237_0025	ENOG4105CH2	amidohydrolase
CCON33237_0029	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CCON33237_0054	ENOG4105EUU	Sel1 domain protein repeat-containing protein
CCON33237_0069	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CCON33237_0072	ENOG4107QYX	exodeoxyribonuclease v alpha
CCON33237_0091	ENOG4108WC9	type VI secretion system effector, hcp1 family
CCON33237_0098	ENOG4108MR7	Arylsulfotransferase
CCON33237_0100	ENOG4108N92	Thiol disulfide Interchange Protein
CCON33237_0102	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CCON33237_0103	ENOG4108KXV	response regulator
CCON33237_0105	ENOG4105DWF	phosphomethylpyrimidine kinase
CCON33237_0108	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CCON33237_0109	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CCON33237_0110	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CCON33237_0111	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CCON33237_0112	ENOG41084M8	50s ribosomal protein L35
CCON33237_0114	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CCON33237_0116	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CCON33237_0117	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CCON33237_0118	ENOG4105C30	Nad-dependent epimerase dehydratase
CCON33237_0119	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
CCON33237_0120	ENOG4105FAW	cDP-glucose 4,6-dehydratase
CCON33237_0122	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CCON33237_0123	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CCON33237_0128	ENOG4105K64	Glycosyl transferase, family 2
CCON33237_0130	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CCON33237_0133	ENOG4105CKK	Glycosyl transferase, family 2
CCON33237_0134	ENOG4105K64	Glycosyl transferase, family 2
CCON33237_0137	ENOG4105BZG	amino acid carrier protein
CCON33237_0138	ENOG4105D1H	recombination factor protein RarA
CCON33237_0141	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CCON33237_0142	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
CCON33237_0143	ENOG4105C22	threonyL-tRNA synthetase
CCON33237_0144	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CCON33237_0145	ENOG4105D82	Glutamate dehydrogenase
CCON33237_0148	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CCON33237_0150	ENOG4108YXA	Membrane
CCON33237_0152	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CCON33237_0153	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CCON33237_0154	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
CCON33237_0155	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CCON33237_0156	ENOG4105F4R	Transcriptional regulator mode
CCON33237_0159	ENOG4105CGK	Exodeoxyribonuclease III
CCON33237_0161	ENOG4105CA0	peroxidase
CCON33237_0165	ENOG4105FDK	ABC transporter
CCON33237_0167	ENOG4107XSR	periplasmic solute binding protein
CCON33237_0173	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CCON33237_0178	ENOG4105CEY	Amp-dependent synthetase and ligase
CCON33237_0180	ENOG4108JIR	Flagellum-specific ATP synthase
CCON33237_0181	ENOG4105EUJ	GTP cyclohydrolase i
CCON33237_0182	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CCON33237_0183	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CCON33237_0185	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CCON33237_0186	ENOG4105C0P	Mg chelatase subunit ChlI
CCON33237_0187	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CCON33237_0188	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CCON33237_0189	ENOG4105EE5	Membrane protein terC
CCON33237_0203	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCON33237_0204	ENOG4105C8S	subunit m
CCON33237_0205	ENOG4105D65	subunit l
CCON33237_0207	ENOG4107UFS	subunit j
CCON33237_0208	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCON33237_0209	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CCON33237_0214	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CCON33237_0215	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCON33237_0216	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CCON33237_0217	ENOG4105IBP	Cyclic peptide transporter
CCON33237_0218	ENOG4105CSA	Coproporphyrinogen iii oxidase
CCON33237_0221	ENOG4108VPT	UPF0234 protein
CCON33237_0223	ENOG4105C5I	Dehydrogenase
CCON33237_0224	ENOG4106032	Glutathionylspermidine synthase
CCON33237_0228	ENOG4105C58	cytochrome c oxidase accessory protein ccog
CCON33237_0232	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CCON33237_0242	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CCON33237_0243	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CCON33237_0248	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CCON33237_0249	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CCON33237_0253	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CCON33237_0254	ENOG41082DI	50s ribosomal protein l31
CCON33237_0259	ENOG4105CHM	Aminotransferase
CCON33237_0260	ENOG4105D6E	homoserine dehydrogenase
CCON33237_0261	ENOG41082UM	UPF0102 protein
CCON33237_0264	ENOG4105C3M	thioredoxin reductase
CCON33237_0265	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CCON33237_0271	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CCON33237_0273	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CCON33237_0274	ENOG4108N92	Thiol disulfide Interchange Protein
CCON33237_0275	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCON33237_0276	ENOG4108F90	4-oxalocrotonate tautomerase
CCON33237_0279	ENOG4105DEF	Extracellular solute-binding protein, family 5
CCON33237_0282	ENOG4108RZA	ABC transporter
CCON33237_0283	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CCON33237_0284	ENOG4105WPN	DNA integration recombination invertion protein
CCON33237_0285	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CCON33237_0287	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CCON33237_0288	ENOG4105DFF	Rod shape-determining protein mreb
CCON33237_0290	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CCON33237_0293	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CCON33237_0295	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
CCON33237_0296	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CCON33237_0303	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CCON33237_0305	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CCON33237_0306	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CCON33237_0307	ENOG4108UJD	30S ribosomal protein S9
CCON33237_0308	ENOG4105CDV	Ompa motb domain protein
CCON33237_0309	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CCON33237_0310	ENOG4105CBX	hi0933 family
CCON33237_0311	ENOG4107RDB	Major Facilitator
CCON33237_0312	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CCON33237_0319	ENOG4105D7T	ABC transporter
CCON33237_0324	ENOG4108ZEX	molybdopterin converting factor, subunit 2
CCON33237_0330	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CCON33237_0331	ENOG4108RCM	Nitroreductase
CCON33237_0332	ENOG4105BZU	Histidine kinase
CCON33237_0333	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
CCON33237_0334	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CCON33237_0338	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CCON33237_0341	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CCON33237_0342	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CCON33237_0343	ENOG4105C6K	Malic enzyme
CCON33237_0344	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CCON33237_0346	ENOG41067XF	inhibitor
CCON33237_0347	ENOG4108XUR	Pfam:DUF178
CCON33237_0351	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
CCON33237_0352	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CCON33237_0356	ENOG4105QAX	Iron-sulfur
CCON33237_0357	ENOG4107SJW	iron permease, FTR1
CCON33237_0362	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCON33237_0367	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CCON33237_0369	ENOG4105C31	Tryptophanyl-tRNA synthetase
CCON33237_0371	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CCON33237_0375	ENOG4105KPY	Small multidrug resistance protein
CCON33237_0377	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CCON33237_0378	ENOG4105M7K	Involved in the transcription termination process (By similarity)
CCON33237_0395	ENOG4108V0P	LemA family
CCON33237_0396	ENOG4105HA9	of methanol dehydrogenase type
CCON33237_0402	ENOG4105C2D	reductase
CCON33237_0403	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CCON33237_0407	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CCON33237_0408	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CCON33237_0416	ENOG4105CEV	competence damage-inducible protein
CCON33237_0417	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CCON33237_0419	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CCON33237_0420	ENOG4105DWV	Homoserine O-trans-acetylase
CCON33237_0421	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CCON33237_0423	ENOG4105UNS	Pfam:DUF419
CCON33237_0424	ENOG4105DFU	Cell wall formation (By similarity)
CCON33237_0427	ENOG4105C98	muts2 protein
CCON33237_0428	ENOG4105BZU	Histidine kinase
CCON33237_0429	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CCON33237_0431	ENOG4105C2M	dna polymerase I
CCON33237_0434	ENOG4105M8K	biopolymer transport protein
CCON33237_0435	ENOG4105M15	transport protein ExbD
CCON33237_0438	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CCON33237_0439	ENOG4105D00	flagellar biosynthetic protein flhB
CCON33237_0442	ENOG4105K46	50S ribosomal protein l27
CCON33237_0445	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CCON33237_0447	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CCON33237_0448	ENOG4107QJE	Chromosome Partitioning Protein
CCON33237_0449	ENOG4105FA0	parb-like partition protein
CCON33237_0450	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CCON33237_0451	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CCON33237_0452	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCON33237_0453	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CCON33237_0454	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CCON33237_0455	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CCON33237_0456	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CCON33237_0457	ENOG4105E02	MotA TolQ exbB proton channel
CCON33237_0458	ENOG4105M8F	Biopolymer transport protein exbD tolR
CCON33237_0460	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CCON33237_0463	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CCON33237_0464	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CCON33237_0465	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CCON33237_0466	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CCON33237_0468	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CCON33237_0470	ENOG4105SCY	DNAK suppressor
CCON33237_0471	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CCON33237_0472	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CCON33237_0473	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCON33237_0476	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCON33237_0478	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CCON33237_0480	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CCON33237_0482	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CCON33237_0485	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CCON33237_0488	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCON33237_0489	ENOG4105C8J	)-transporter
CCON33237_0490	ENOG4105C8J	)-transporter
CCON33237_0491	ENOG4105C8J	)-transporter
CCON33237_0493	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CCON33237_0494	ENOG4107QSA	Oxaloacetate decarboxylase
CCON33237_0496	ENOG4105CK2	sodium dicarboxylate symporter
CCON33237_0497	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CCON33237_0498	ENOG4105CDY	transcriptional regulatory protein
CCON33237_0501	ENOG4105C59	p-type ATPase
CCON33237_0504	ENOG4105CH7	arginosuccinase
CCON33237_0505	ENOG4105C8Q	Methyl-accepting chemotaxis
CCON33237_0510	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CCON33237_0511	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CCON33237_0516	ENOG4105VFU	Rna-binding protein
CCON33237_0517	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CCON33237_0519	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CCON33237_0521	ENOG4105DC7	peptidase M24
CCON33237_0522	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCON33237_0523	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CCON33237_0524	ENOG4107R21	site-determining protein
CCON33237_0526	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCON33237_0527	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CCON33237_0528	ENOG4105DD5	Flagellar motor switch protein
CCON33237_0529	ENOG4108URH	decarboxylase
CCON33237_0530	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CCON33237_0537	ENOG4105QAX	Iron-sulfur
CCON33237_0541	ENOG41078M4	ABC transporter
CCON33237_0542	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
CCON33237_0543	ENOG4105C8W	ABC transporter
CCON33237_0548	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CCON33237_0552	ENOG4105F0N	pyrophosphate phospho-hydrolase
CCON33237_0554	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CCON33237_0555	ENOG4105C9M	aspartyl-trna synthetase
CCON33237_0556	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CCON33237_0557	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CCON33237_0558	ENOG4105BZU	Histidine kinase
CCON33237_0559	ENOG4105F8V	Hydrolase, tatD family
CCON33237_0561	ENOG4105K6T	rare lipoprotein A
CCON33237_0562	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CCON33237_0563	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CCON33237_0566	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CCON33237_0568	ENOG4105CJN	penicillin-binding protein
CCON33237_0569	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CCON33237_0570	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CCON33237_0572	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CCON33237_0574	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCON33237_0579	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CCON33237_0580	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CCON33237_0584	ENOG4107RN3	metallophosphoesterase
CCON33237_0585	ENOG4105DJ4	phosphatidylserine decarboxylase
CCON33237_0586	ENOG4105C3G	gtp-binding protein
CCON33237_0587	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CCON33237_0589	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CCON33237_0591	ENOG4108YZG	isomerase
CCON33237_0593	ENOG4108Z4T	Peptidase M50
CCON33237_0594	ENOG4105C3F	Signal peptidase i
CCON33237_0595	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CCON33237_0597	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CCON33237_0602	ENOG4105D00	flagellar biosynthetic protein flhB
CCON33237_0603	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CCON33237_0604	ENOG4105BZU	Histidine kinase
CCON33237_0611	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
CCON33237_0612	ENOG4105C1V	Peptidase, M16
CCON33237_0613	ENOG4105CB5	ATP-dependent DNA helicase recG
CCON33237_0615	ENOG4105E0A	ABC, transporter
CCON33237_0616	ENOG4105EHG	Permease protein
CCON33237_0619	ENOG4105RX8	Protein of unknown function (DUF1523)
CCON33237_0621	ENOG4105MS2	ribosomal subunit Interface protein
CCON33237_0626	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
CCON33237_0628	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CCON33237_0629	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CCON33237_0630	ENOG4107QIJ	Aconitate hydratase 2
CCON33237_0632	ENOG4105EMU	Dehydrogenase
CCON33237_0633	ENOG4107S6Z	Na H antiporter
CCON33237_0634	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CCON33237_0635	ENOG4105C7B	Threonine dehydratase
CCON33237_0637	ENOG4105EZR	dyp-type peroxidase family protein
CCON33237_0639	ENOG4105C8Q	Methyl-accepting chemotaxis
CCON33237_0640	ENOG4105C8Q	Methyl-accepting chemotaxis
CCON33237_0641	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CCON33237_0642	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CCON33237_0643	ENOG4105GXZ	Ferredoxin-type protein NapH
CCON33237_0644	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
CCON33237_0654	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CCON33237_0657	ENOG4105D0M	Protease HtpX homolog
CCON33237_0660	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CCON33237_0661	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CCON33237_0662	ENOG4105D52	delta-aminolevulinic acid dehydratase
CCON33237_0663	ENOG4105DBV	ornithine carbamoyltransferase
CCON33237_0664	ENOG4105T1H	UPF0763 protein
CCON33237_0665	ENOG4105D4P	Coproporphyrinogen iii oxidase
CCON33237_0672	ENOG4108UDW	Transcriptional regulator, luxr family
CCON33237_0678	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CCON33237_0682	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CCON33237_0683	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CCON33237_0684	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CCON33237_0685	ENOG4108VZM	50s ribosomal protein L10
CCON33237_0686	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CCON33237_0690	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CCON33237_0691	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CCON33237_0695	ENOG4108RMU	ferritin dps family protein
CCON33237_0698	ENOG4105YIC	Major outer membrane protein
CCON33237_0700	ENOG4105CRE	cytochrome C
CCON33237_0703	ENOG4105CJN	penicillin-binding protein
CCON33237_0705	ENOG4108ZC9	flagellar basal-body rod protein flgc
CCON33237_0706	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CCON33237_0708	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CCON33237_0710	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CCON33237_0711	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CCON33237_0716	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CCON33237_0717	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CCON33237_0718	ENOG4105VIE	preprotein translocase, subunit YajC
CCON33237_0719	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCON33237_0720	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCON33237_0722	ENOG4105C8T	Leucyl-tRNA synthetase
CCON33237_0724	ENOG4105BZU	Histidine kinase
CCON33237_0726	ENOG4108JA2	transcriptioN-repair coupling factor
CCON33237_0730	ENOG4105D7W	serine acetyltransferase
CCON33237_0733	ENOG4105VB9	50S ribosomal protein l28
CCON33237_0736	ENOG4105DJV	ribulose-phosphate 3-epimerase
CCON33237_0737	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CCON33237_0739	ENOG4105C8J	)-transporter
CCON33237_0741	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CCON33237_0744	ENOG4107XM3	UPF0442 protein
CCON33237_0746	ENOG4107YD3	Thioesterase
CCON33237_0749	ENOG4105VG0	50S ribosomal protein l34
CCON33237_0750	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CCON33237_0751	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CCON33237_0752	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CCON33237_0754	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CCON33237_0755	ENOG4105NF4	modulator of drug activity
CCON33237_0758	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CCON33237_0760	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CCON33237_0761	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CCON33237_0764	ENOG4105VG1	fes assembly suf system protein
CCON33237_0765	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CCON33237_0766	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CCON33237_0767	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CCON33237_0769	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CCON33237_0774	ENOG4105EWC	Purine nucleoside phosphorylase
CCON33237_0777	ENOG4107QUV	Domain protein
CCON33237_0780	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CCON33237_0781	ENOG4105D60	lipoprotein releasing system transmembrane protein
CCON33237_0783	ENOG4105KNI	merR family transcriptional Regulator
CCON33237_0784	ENOG4105DVC	DnaJ domain protein
CCON33237_0785	ENOG4105C0H	protease
CCON33237_0786	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CCON33237_0792	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CCON33237_0795	ENOG4105EAH	synthase
CCON33237_0796	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CCON33237_0797	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CCON33237_0799	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CCON33237_0800	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CCON33237_0802	ENOG4107VIJ	nudix hydrolase
CCON33237_0803	ENOG4105CJW	magnesium transporter
CCON33237_0804	ENOG4105FAA	peptidase M23
CCON33237_0806	ENOG4107S2Z	UPF0761 membrane protein
CCON33237_0808	ENOG4107S1Q	Phosphatase
CCON33237_0809	ENOG4105C26	Dehydrogenase
CCON33237_0810	ENOG4105EB3	Histidine kinase
CCON33237_0811	ENOG4108STX	response regulator
CCON33237_0816	ENOG410841J	DNA-binding protein Hu
CCON33237_0817	ENOG410802Z	Protein of unknown function (DUF328)
CCON33237_0818	ENOG4105DTJ	flagellar hook-associated protein
CCON33237_0819	ENOG4105CNU	cell division protein FtsK
CCON33237_0822	ENOG41067CV	Integrase
CCON33237_0835	ENOG4105VBD	cytochrome C, class I
CCON33237_0837	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CCON33237_0838	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CCON33237_0839	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CCON33237_0844	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCON33237_0845	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CCON33237_0847	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CCON33237_0848	ENOG41082XB	radical SAM domain protein
CCON33237_0851	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CCON33237_0852	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CCON33237_0853	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CCON33237_0854	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CCON33237_0855	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CCON33237_0858	ENOG4107QN2	dihydrolipoyl dehydrogenase
CCON33237_0866	ENOG4105KB8	(LipO)protein
CCON33237_0867	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CCON33237_0869	ENOG4105CHV	Transcription elongation factor NusA
CCON33237_0872	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CCON33237_0875	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CCON33237_0876	ENOG4105C5F	glutamine synthetase
CCON33237_0879	ENOG4105CFP	Peptidase U32
CCON33237_0880	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CCON33237_0883	ENOG4105CFC	Transporter
CCON33237_0884	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CCON33237_0885	ENOG4105EGD	dinuclear metal center protein, YbgI family
CCON33237_0887	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CCON33237_0888	ENOG4105EI2	Pseudouridine synthase
CCON33237_0889	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCON33237_0891	ENOG4105VB6	UPF0109 protein
CCON33237_0892	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CCON33237_0893	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CCON33237_0894	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CCON33237_0896	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CCON33237_0897	ENOG4105CY3	ABC transporter, permease
CCON33237_0902	ENOG4105D49	3-dehydroquinate synthase
CCON33237_0904	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CCON33237_0905	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CCON33237_0906	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CCON33237_0909	ENOG4105D41	biosynthesis protein thiH
CCON33237_0914	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CCON33237_0915	ENOG4105CUT	histidyl-tRNA synthetase
CCON33237_0916	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CCON33237_0917	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CCON33237_0918	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CCON33237_0921	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CCON33237_0922	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CCON33237_0924	ENOG4105ED9	Protein of unknown function (DUF455)
CCON33237_0926	ENOG4105C8Q	Methyl-accepting chemotaxis
CCON33237_0927	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CCON33237_0928	ENOG4105D7Q	type ii secretion system
CCON33237_0929	ENOG4107QHF	type ii secretion system protein e
CCON33237_0937	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CCON33237_0938	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CCON33237_0939	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CCON33237_0940	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CCON33237_0941	ENOG4105CDH	Citrulline--aspartate ligase
CCON33237_0942	ENOG4105D05	Receptor
CCON33237_0944	ENOG410854I	s4 domain protein
CCON33237_0945	ENOG4105K8N	protein family UPF0079, ATPase
CCON33237_0946	ENOG4108IUZ	ABC transporter
CCON33237_0947	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCON33237_0954	ENOG4105CNI	cell division protein FtsW
CCON33237_0955	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CCON33237_0956	ENOG4107T5V	SNARE associated Golgi
CCON33237_0957	ENOG4105D01	(LipO)protein
CCON33237_0958	ENOG4105D01	(LipO)protein
CCON33237_0959	ENOG4108UMI	ABC transporter, permease
CCON33237_0960	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CCON33237_0963	ENOG4108JQB	penicillin-binding protein 1C
CCON33237_0964	ENOG4105C4R	Atp-dependent dna helicase
CCON33237_0965	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CCON33237_0967	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CCON33237_0970	ENOG4105C9X	ppx gppa phosphatase
CCON33237_0972	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CCON33237_0973	ENOG4105CN1	protease
CCON33237_0974	ENOG4105C8V	SAICAR synthetase
CCON33237_0976	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CCON33237_0978	ENOG4105E9Q	Acyl-transferase
CCON33237_0979	ENOG4105C8Q	Methyl-accepting chemotaxis
CCON33237_0980	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CCON33237_0982	ENOG41086B8	CoB-CoM heterodisulfide reductase
CCON33237_0983	ENOG4105E33	succinate dehydrogenase
CCON33237_0984	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CCON33237_0986	ENOG4105E0A	ABC, transporter
CCON33237_0991	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CCON33237_0992	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
CCON33237_0994	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CCON33237_0995	ENOG4105E9K	Isocitrate dehydrogenase
CCON33237_0996	ENOG4105HHA	aminodeoxychorismate lyase
CCON33237_0998	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CCON33237_0999	ENOG4105C45	hydrogenase expression formation protein (HypE)
CCON33237_1000	ENOG4105CQS	hydrogenase expression formation protein HypD
CCON33237_1001	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
CCON33237_1002	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CCON33237_1005	ENOG4105MRR	Transcriptional regulator (By similarity)
CCON33237_1008	ENOG4108USZ	hydrogenase
CCON33237_1009	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
CCON33237_1010	ENOG4105DPX	Hydrogenase, large subunit
CCON33237_1011	ENOG4105E3S	small subunit
CCON33237_1012	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CCON33237_1013	ENOG4105C6K	Malic enzyme
CCON33237_1014	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CCON33237_1015	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCON33237_1016	ENOG4108ZP8	Acetolactate synthase small subunit
CCON33237_1017	ENOG4105C7K	acetolactate synthase
CCON33237_1018	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CCON33237_1022	ENOG4105QTX	Pfam:UPF0153
CCON33237_1023	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CCON33237_1025	ENOG4105CAY	ferredoxin--nadp reductase
CCON33237_1026	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CCON33237_1027	ENOG4105DTR	rard protein
CCON33237_1028	ENOG4105FR1	rard protein
CCON33237_1030	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
CCON33237_1034	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CCON33237_1035	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
CCON33237_1036	ENOG4105EJ9	Membrane
CCON33237_1037	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CCON33237_1039	ENOG4105E1Q	flagellar hook-associated protein
CCON33237_1042	ENOG4105YKR	
CCON33237_1047	ENOG4105DTS	flagellar hook-associated
CCON33237_1050	ENOG4107XNU	peptidase
CCON33237_1051	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CCON33237_1052	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CCON33237_1055	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CCON33237_1059	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CCON33237_1061	ENOG4105CJR	Integral membrane protein (MviN
CCON33237_1062	ENOG4105C8N	cysteinyl-tRNA synthetase
CCON33237_1063	ENOG4105BZ1	(ABC) transporter
CCON33237_1064	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CCON33237_1066	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CCON33237_1067	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
CCON33237_1068	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CCON33237_1069	ENOG4105DZP	Membrane-associated zinc metalloprotease
CCON33237_1070	ENOG4105DFA	alanine racemase domain protein
CCON33237_1074	ENOG4105VSH	4-oxalocrotonate tautomerase
CCON33237_1075	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CCON33237_1103	ENOG4105ED4	portal protein
CCON33237_1117	ENOG4108WTW	DNA transposition protein
CCON33237_1125	ENOG4108Z40	Transcriptional regulator
CCON33237_1126	ENOG4105KQC	Competence protein
CCON33237_1135	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CCON33237_1137	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCON33237_1138	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CCON33237_1140	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CCON33237_1142	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CCON33237_1143	ENOG4105X6C	Flagellar basal body-associated protein FliL
CCON33237_1144	ENOG4108Z66	YbaK ebsC protein
CCON33237_1146	ENOG4105EN6	Membrane
CCON33237_1149	ENOG41090R7	Ferric uptake
CCON33237_1158	ENOG4108PQF	modD protein
CCON33237_1159	ENOG4105C94	Transporter
CCON33237_1163	ENOG4105C5H	ABC transporter
CCON33237_1164	ENOG4105UQX	Mate efflux family protein
CCON33237_1170	ENOG4105C8U	phosphate abc transporter
CCON33237_1172	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CCON33237_1174	ENOG41076HS	cation diffusion facilitator family transporter
CCON33237_1177	ENOG4105E5Q	amino acid AbC transporter
CCON33237_1178	ENOG4105DSP	amino acid AbC transporter
CCON33237_1180	ENOG4105EAB	amino acid AbC transporter
CCON33237_1182	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CCON33237_1183	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CCON33237_1186	ENOG4105MEW	serine threonine protein phosphatase
CCON33237_1191	ENOG4105C25	Primosomal protein n'
CCON33237_1192	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CCON33237_1193	ENOG4105CDU	Replicative dna helicase
CCON33237_1195	ENOG4105EMK	carboxylate amino acid amine transporter
CCON33237_1197	ENOG4105BZS	acriflavin resistance protein
CCON33237_1200	ENOG4105CN7	Flagellar biosynthetic protein FliP
CCON33237_1201	ENOG4107XSU	flagellar motor protein motb
CCON33237_1202	ENOG4105E14	MotA TolQ exbB proton channel
CCON33237_1203	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CCON33237_1204	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CCON33237_1206	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CCON33237_1207	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CCON33237_1219	ENOG4105DVY	radical SAM domain protein
CCON33237_1220	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CCON33237_1221	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CCON33237_1223	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
CCON33237_1224	ENOG4105R3P	Inner membrane protein yagU
CCON33237_1226	ENOG4106HX4	
CCON33237_1227	ENOG4105CAG	UPF0210 protein
CCON33237_1228	ENOG4105VUC	UPF0237 protein
CCON33237_1229	ENOG4105D1F	ATP-binding protein
CCON33237_1231	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CCON33237_1232	ENOG4105ETX	regulatoR
CCON33237_1236	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CCON33237_1238	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CCON33237_1241	ENOG4108JQC	penicillin-binding protein 1A
CCON33237_1243	ENOG4105DIJ	Phosphoethanolamine transferase
CCON33237_1244	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CCON33237_1246	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CCON33237_1247	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CCON33237_1250	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CCON33237_1251	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CCON33237_1252	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
CCON33237_1259	ENOG4105HDK	L-asparaginase
CCON33237_1263	ENOG4105CGA	flagellar basal-body rod protein FlgG
CCON33237_1264	ENOG4105KTQ	flagellar basal-body rod protein
CCON33237_1265	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCON33237_1267	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CCON33237_1271	ENOG4105D2N	Aldolase
CCON33237_1272	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CCON33237_1273	ENOG4105CSM	endonuclease III
CCON33237_1274	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CCON33237_1275	ENOG4105CSR	polyphosphate kinase 2
CCON33237_1277	ENOG4105CFG	Acts as a chaperone (By similarity)
CCON33237_1278	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCON33237_1279	ENOG4108122	heat-inducible transcription repressor
CCON33237_1282	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CCON33237_1283	ENOG4107QID	Threonine synthase
CCON33237_1286	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CCON33237_1287	ENOG4105C4K	Nad synthetase
CCON33237_1288	ENOG4105C5X	domain protein
CCON33237_1289	ENOG4105YIC	Major outer membrane protein
CCON33237_1291	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CCON33237_1292	ENOG4108KS2	transglutaminase domain protein
CCON33237_1295	ENOG4105CIN	aminoacyl-histidine dipeptidase
CCON33237_1296	ENOG4105CD3	dihydroorotase
CCON33237_1297	ENOG4105CXT	aspartate transcarbamylase
CCON33237_1301	ENOG4105D7B	Flagellar biosynthesis protein flha
CCON33237_1302	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
CCON33237_1303	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CCON33237_1306	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CCON33237_1307	ENOG4105DTN	riboflavin biosynthesis protein ribF
CCON33237_1309	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CCON33237_1311	ENOG4105EEI	dihydropteroate synthase
CCON33237_1314	ENOG4105CFH	Aspartokinase
CCON33237_1317	ENOG4105D05	Receptor
CCON33237_1319	ENOG4105CSA	Coproporphyrinogen iii oxidase
CCON33237_1321	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CCON33237_1324	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CCON33237_1326	ENOG4105PXI	polysaccharide deacetylase
CCON33237_1327	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CCON33237_1329	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CCON33237_1331	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CCON33237_1332	ENOG4108UUM	single-stranded DNA-binding protein
CCON33237_1333	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CCON33237_1338	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CCON33237_1339	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CCON33237_1343	ENOG4105F4G	Membrane
CCON33237_1345	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CCON33237_1348	ENOG4105DVI	reductase, NrfD
CCON33237_1349	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CCON33237_1350	ENOG4107QY8	reductase
CCON33237_1351	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CCON33237_1352	ENOG4108IJ0	Aspartate ammonia-lyase
CCON33237_1353	ENOG4105C5H	ABC transporter
CCON33237_1354	ENOG4108XC3	NADH ubiquinone oxidoreductase
CCON33237_1355	ENOG4107QP8	phosphohexose isomerase
CCON33237_1356	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CCON33237_1357	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CCON33237_1359	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CCON33237_1360	ENOG4108S24	Fumarate reduCtase
CCON33237_1361	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CCON33237_1362	ENOG4105E33	succinate dehydrogenase
CCON33237_1363	ENOG4106H3A	restriction
CCON33237_1364	ENOG4105KNE	Phosphatidate cytidylyltransferase
CCON33237_1365	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CCON33237_1366	ENOG4105C2W	permease
CCON33237_1368	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CCON33237_1371	ENOG4107QY8	reductase
CCON33237_1375	ENOG4107RAN	Peptidase, M16
CCON33237_1377	ENOG4105C8Q	Methyl-accepting chemotaxis
CCON33237_1380	ENOG4105CDA	abc transporter atp-binding protein
CCON33237_1381	ENOG4105E5Q	amino acid AbC transporter
CCON33237_1382	ENOG4105CK7	Sodium proline symporter
CCON33237_1383	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CCON33237_1384	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CCON33237_1385	ENOG4105EA8	2-Nitropropane dioxygenase
CCON33237_1386	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CCON33237_1388	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CCON33237_1389	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CCON33237_1392	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CCON33237_1396	ENOG4105C34	Pseudouridine synthase
CCON33237_1397	ENOG4105CNI	cell division protein FtsW
CCON33237_1399	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CCON33237_1400	ENOG4105DWF	phosphomethylpyrimidine kinase
CCON33237_1403	ENOG4105BZU	Histidine kinase
CCON33237_1406	ENOG4105C0B	DNA polymerase III (alpha subunit)
CCON33237_1408	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CCON33237_1410	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CCON33237_1412	ENOG4105C12	Phosphoribosylglycinamide synthetase
CCON33237_1414	ENOG4105C2C	drug resistance transporter, Bcr CflA
CCON33237_1424	ENOG4105CRQ	synthase (Component I)
CCON33237_1426	ENOG4106R49	Methyltransferase
CCON33237_1429	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CCON33237_1430	ENOG4105P0I	Adenylate cyclase
CCON33237_1433	ENOG4105W2B	Flagellar assembly protein
CCON33237_1434	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CCON33237_1435	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CCON33237_1436	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CCON33237_1437	ENOG4105CQC	Prephenate dehydratase
CCON33237_1438	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CCON33237_1440	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CCON33237_1441	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CCON33237_1444	ENOG4105YFD	chemotaxis, protein
CCON33237_1445	ENOG4105CBS	Chea signal transduction histidine kinase
CCON33237_1446	ENOG4107R88	Chemotaxis protein (CheV)
CCON33237_1448	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CCON33237_1450	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CCON33237_1451	ENOG4105CUZ	uba thif-type nad fad binding protein
CCON33237_1452	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CCON33237_1453	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CCON33237_1454	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
CCON33237_1455	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CCON33237_1456	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
CCON33237_1458	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CCON33237_1459	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CCON33237_1460	ENOG4105C5E	polysaccharide biosynthesis protein
CCON33237_1461	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CCON33237_1462	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
CCON33237_1463	ENOG4105D3Q	Sugar transferase
CCON33237_1464	ENOG4105CGN	Glycosyl transferase (Group 1
CCON33237_1466	ENOG4105CG5	Glycosyl transferase (Group 1
CCON33237_1468	ENOG4105CG5	Glycosyl transferase (Group 1
CCON33237_1469	ENOG4105K64	Glycosyl transferase, family 2
CCON33237_1473	ENOG4107QQG	Dehydrogenase
CCON33237_1475	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CCON33237_1478	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CCON33237_1481	ENOG4107RSR	Malate quinone oxidoreductase
CCON33237_1484	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CCON33237_1485	ENOG4105CP7	Triose-phosphate isomerase
CCON33237_1486	ENOG4105BZA	Phosphoglycerate kinase
CCON33237_1489	ENOG4105HMI	Membrane
CCON33237_1491	ENOG4105C75	arginyL-tRNA synthetase
CCON33237_1492	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CCON33237_1493	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CCON33237_1495	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CCON33237_1498	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CCON33237_1504	ENOG4105XA0	heptosyltransferase ii
CCON33237_1506	ENOG4106WTF	Glycosyl transferase, family 2
CCON33237_1507	ENOG4105DKP	glycosyl transferase, family 9
CCON33237_1508	ENOG4107RA4	Glycosyl transferase (Group 1
CCON33237_1509	ENOG4107BJW	polysaccharide deacetylase
CCON33237_1512	ENOG4107BJW	polysaccharide deacetylase
CCON33237_1516	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CCON33237_1518	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CCON33237_1520	ENOG4105YQ2	50s ribosomal protein l32
CCON33237_1521	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CCON33237_1522	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CCON33237_1523	ENOG4105D3R	alkyl hydroperoxide reductase
CCON33237_1526	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CCON33237_1528	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CCON33237_1532	ENOG4105DD5	Flagellar motor switch protein
CCON33237_1536	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CCON33237_1537	ENOG4105DDQ	anthranilate synthase
CCON33237_1538	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CCON33237_1539	ENOG4105E0F	Histidine kinase
CCON33237_1540	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CCON33237_1541	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CCON33237_1542	ENOG4105CA9	Pyruvate kinase
CCON33237_1543	ENOG4105CH5	extracellular solute-binding protein, family 7
CCON33237_1544	ENOG4105E2X	shikimate dehydrogenase
CCON33237_1547	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CCON33237_1551	ENOG4105CZX	twitching motility protein
CCON33237_1552	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CCON33237_1554	ENOG4108TX7	
CCON33237_1557	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CCON33237_1559	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CCON33237_1560	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CCON33237_1561	ENOG4105CE9	30S ribosomal protein S2
CCON33237_1564	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CCON33237_1568	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CCON33237_1569	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CCON33237_1570	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CCON33237_1571	ENOG4105CHR	reductase
CCON33237_1572	ENOG4108ZPB	UPF0306 protein
CCON33237_1582	ENOG4105NAU	thioesterase Superfamily protein
CCON33237_1587	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
CCON33237_1589	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CCON33237_1590	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CCON33237_1591	ENOG4107WQX	hydrogenase 4 membrane subunit
CCON33237_1592	ENOG4107TDF	Formate hydrogenlyase subunit 4
CCON33237_1593	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CCON33237_1594	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
CCON33237_1598	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCON33237_1599	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCON33237_1600	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CCON33237_1601	ENOG4105CEY	Amp-dependent synthetase and ligase
CCON33237_1602	ENOG4105EAB	amino acid AbC transporter
CCON33237_1603	ENOG4105EAB	amino acid AbC transporter
CCON33237_1604	ENOG4105DRP	amino acid AbC transporter
CCON33237_1605	ENOG4105CDA	abc transporter atp-binding protein
CCON33237_1606	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CCON33237_1609	ENOG4105F27	Major Facilitator
CCON33237_1610	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CCON33237_1611	ENOG4108VCA	G U mismatch-specific DNA glycosylase
CCON33237_1614	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CCON33237_1617	ENOG4108UZ3	Transporter
CCON33237_1618	ENOG4107Y60	(LipO)protein
CCON33237_1620	ENOG4106B0W	Curli production assembly transport component CsgG
CCON33237_1621	ENOG4105UQX	Mate efflux family protein
CCON33237_1622	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CCON33237_1623	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CCON33237_1625	ENOG4105DHP	deoxycytidine triphosphate deaminase
CCON33237_1628	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CCON33237_1629	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CCON33237_1630	ENOG4105D2T	synthase
CCON33237_1631	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
CCON33237_1637	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CCON33237_1638	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CCON33237_1639	ENOG4105WMR	Protein CrcB homolog
CCON33237_1642	ENOG4105BZN	citrate synthase
CCON33237_1643	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CCON33237_1644	ENOG4106R49	Methyltransferase
CCON33237_1646	ENOG4105E0C	molybdate abc transporter
CCON33237_1647	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CCON33237_1649	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CCON33237_1650	ENOG4105F4R	Transcriptional regulator mode
CCON33237_1655	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
CCON33237_1659	ENOG4105E63	Pfam:DUF178
CCON33237_1660	ENOG4105VS8	Flagellar biosynthetic protein fliq
CCON33237_1663	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CCON33237_1664	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CCON33237_1667	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCON33237_1668	ENOG4105DB1	molybdopterin oxidoreductase
CCON33237_1669	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CCON33237_1670	ENOG4105BZW	Glycerate kinase
CCON33237_1671	ENOG4105C6Z	Gluconate
CCON33237_1676	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CCON33237_1678	ENOG4105F23	Fibronectin-binding protein
CCON33237_1685	ENOG4105KME	endoribonuclease L-psp
CCON33237_1689	ENOG4105C37	(CBS) domain
CCON33237_1690	ENOG4105C8J	)-transporter
CCON33237_1692	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
CCON33237_1696	ENOG4107SUZ	Sodium/hydrogen exchanger family
CCON33237_1706	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CCON33237_1709	ENOG4105EQJ	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide (By similarity)
CCON33237_1711	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CCON33237_1712	ENOG41068HQ	Protein of unknown function (DUF493)
CCON33237_1714	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CCON33237_1715	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CCON33237_1717	ENOG4105C0H	protease
CCON33237_1718	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CCON33237_1719	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CCON33237_1720	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CCON33237_1725	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CCON33237_1728	ENOG4108ZT0	50S ribosomal protein l17
CCON33237_1729	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CCON33237_1730	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CCON33237_1731	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CCON33237_1732	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCON33237_1734	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CCON33237_1735	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CCON33237_1736	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CCON33237_1737	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CCON33237_1738	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CCON33237_1739	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CCON33237_1740	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CCON33237_1741	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CCON33237_1742	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CCON33237_1743	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCON33237_1744	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CCON33237_1745	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CCON33237_1746	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CCON33237_1747	ENOG41084HJ	50s ribosomal protein l29
CCON33237_1748	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CCON33237_1749	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CCON33237_1750	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CCON33237_1751	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CCON33237_1752	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCON33237_1753	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CCON33237_1754	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CCON33237_1755	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CCON33237_1760	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CCON33237_1761	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CCON33237_1762	ENOG4105C28	cystathionine
CCON33237_1764	ENOG4105C87	Aminotransferase class I and II
CCON33237_1766	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CCON33237_1767	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CCON33237_1769	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CCON33237_1770	ENOG4105BZU	Histidine kinase
CCON33237_1771	ENOG4105BZU	Histidine kinase
CCON33237_1773	ENOG4105D64	Mechanosensitive ion channel
CCON33237_1774	ENOG4107B2H	carbonic anhydrase
CCON33237_1775	ENOG4105HFZ	Membrane
CCON33237_1776	ENOG4105NU9	Preprotein translocase subunit SecG
CCON33237_1778	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CCON33237_1785	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CCON33237_1788	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CCON33237_1791	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CCON33237_1792	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CCON33237_1795	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CCON33237_1796	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CCON33237_1797	ENOG4108MR7	Arylsulfotransferase
CCON33237_1799	ENOG4105C01	Dihydroxy-acid dehydratase
CCON33237_1800	ENOG4105CGY	Dna recombination protein
CCON33237_1802	ENOG4108RAC	Rubrerythrin
CCON33237_1810	ENOG4107QW4	alcohol dehydrogenase
CCON33237_1815	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CCON33237_1816	ENOG4107QTF	adenylosuccinate lyase
CCON33237_1817	ENOG4105EI2	Pseudouridine synthase
CCON33237_1818	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CCON33237_1820	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CCON33237_1822	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CCON33237_1823	ENOG4105CN5	Metallo-Beta-Lactamase
CCON33237_1824	ENOG4105C2X	Arabinose 5-phosphate isomerase
CCON33237_1825	ENOG4105FE9	pseudouridine synthase
CCON33237_1826	ENOG4105EUU	Sel1 domain protein repeat-containing protein
CCON33237_1829	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CCON33237_1834	ENOG4105CRE	cytochrome C
CCON33237_1835	ENOG4105DVI	reductase, NrfD
CCON33237_1836	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CCON33237_1837	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CCON33237_1838	ENOG4105V2T	cytochrome C
CCON33237_1839	ENOG4105BZU	Histidine kinase
CCON33237_1840	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CCON33237_1841	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CCON33237_1843	ENOG4105BZE	flagellar hook protein, FlgE
CCON33237_1844	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
CCON33237_1846	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CCON33237_1848	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)