locus-tag	class	description
A6J90_00005	COG1064	alcohol dehydrogenase
A6J90_00020	COG1204	response to ionizing radiation
A6J90_00025	COG0732	type I restriction modification DNA specificity domain
A6J90_00035	COG3177	Filamentation induced by cAMP protein fic
A6J90_00080	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6J90_00085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A6J90_00095	COG0839	Belongs to the complex I subunit 6 family
A6J90_00130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6J90_00135	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6J90_00140	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6J90_00155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J90_00160	COG0601	transmembrane transport
A6J90_00170	COG0277	FAD linked oxidase domain protein
A6J90_00180	COG4615	Cyclic peptide transporter
A6J90_00280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A6J90_00285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A6J90_00300	COG0140	phosphoribosyl-ATP diphosphatase activity
A6J90_00300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A6J90_00305	COG2171	N-acyltransferase activity
A6J90_00310	COG0489	protein tyrosine kinase activity
A6J90_00315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A6J90_00315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A6J90_00325	COG2046	Belongs to the sulfate adenylyltransferase family
A6J90_00330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A6J90_00345	COG0748	coenzyme F420 binding
A6J90_00350	COG4771	TonB-dependent receptor
A6J90_00355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J90_00360	COG1120	ATPase activity
A6J90_00365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J90_00375	COG0477	Major facilitator Superfamily
A6J90_00380	COG1194	a g-specific adenine glycosylase
A6J90_00410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J90_00410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J90_00420	COG1760	l-serine dehydratase
A6J90_00425	COG0814	amino acid
A6J90_00440	COG0811	peptide transport
A6J90_00445	COG0848	biopolymer transport protein
A6J90_00490	COG0358	DNA primase activity
A6J90_00505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A6J90_00510	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A6J90_00525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A6J90_00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A6J90_00535	COG1127	ABC transporter
A6J90_00545	COG3218	ABC-type transport auxiliary lipoprotein component
A6J90_00545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A6J90_00555	COG0024	Methionine aminopeptidase
A6J90_00560	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A6J90_00565	COG0791	NLP P60 protein
A6J90_00590	COG0672	)-iron permease
A6J90_00615	COG1136	(ABC) transporter
A6J90_00665	COG1793	dna ligase
A6J90_00690	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A6J90_00695	COG1987	bacterial-type flagellum assembly
A6J90_00710	COG1218	3'(2'),5'-bisphosphate nucleotidase
A6J90_00715	COG0372	Belongs to the citrate synthase family
A6J90_00725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A6J90_00730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J90_00740	COG2936	dipeptidyl-peptidase activity
A6J90_00755	COG0201	protein transport
A6J90_00760	COG0200	Binds to the 23S rRNA
A6J90_00825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A6J90_00835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A6J90_00845	COG0088	Forms part of the polypeptide exit tunnel
A6J90_00850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A6J90_00860	COG1187	pseudouridine synthase activity
A6J90_00865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A6J90_00880	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A6J90_00920	COG0066	3-isopropylmalate dehydratase activity
A6J90_00985	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A6J90_00990	COG1749	Flagellar hook protein flgE
A6J90_01005	COG0592	DNA-directed DNA polymerase activity
A6J90_01010	COG0187	DNA topoisomerase II activity
A6J90_01025	COG2056	Na+-H+ antiporter family
A6J90_01030	COG0069	glutamate synthase activity
A6J90_01030	COG0070	glutamate synthase
A6J90_01030	COG0067	glutamate synthase
A6J90_01040	COG0493	'glutamate synthase
A6J90_01055	COG1592	Rubrerythrin
A6J90_01060	COG0129	dihydroxy-acid dehydratase activity
A6J90_01065	COG3477	response to acidic pH
A6J90_01070	COG3477	response to acidic pH
A6J90_01080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A6J90_01095	COG0840	transmembrane signaling receptor activity
A6J90_01105	COG0179	Fumarylacetoacetate (FAA) hydrolase
A6J90_01110	COG0564	pseudouridine synthase activity
A6J90_01115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A6J90_01120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J90_01130	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A6J90_01135	COG0504	CTP synthase activity
A6J90_01145	COG0252	asparaginase activity
A6J90_01195	COG2814	Major facilitator Superfamily
A6J90_01230	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A6J90_01260	COG0471	metal ion transport
A6J90_01275	COG0471	metal ion transport
A6J90_01320	COG1776	CheC inhibitor of MCP methylation
A6J90_01320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J90_01325	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J90_01330	COG1191	sigma factor activity
A6J90_01340	COG0455	bacterial-type flagellum organization
A6J90_01345	COG1419	protein localization to endoplasmic reticulum
A6J90_01350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6J90_01360	COG0402	S-adenosylhomocysteine deaminase activity
A6J90_01365	COG0616	signal peptide processing
A6J90_01385	COG1139	Iron-sulfur cluster binding protein
A6J90_01390	COG0247	lactate metabolic process
A6J90_01420	COG1271	oxidase subunit
A6J90_01425	COG1294	oxidase, subunit
A6J90_01430	COG1794	racemase activity, acting on amino acids and derivatives
A6J90_01440	COG1027	Aspartate ammonia-lyase
A6J90_01445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A6J90_01515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A6J90_01515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A6J90_01520	COG1192	Involved in chromosome partitioning
A6J90_01525	COG1475	DNA binding
A6J90_01535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A6J90_01540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A6J90_01560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A6J90_01565	COG0811	peptide transport
A6J90_01570	COG0848	biopolymer transport protein
A6J90_01585	COG2885	chlorophyll binding
A6J90_01595	COG1047	Peptidyl-prolyl cis-trans
A6J90_01600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A6J90_01605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6J90_01610	COG0037	tRNA processing
A6J90_01625	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A6J90_01645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J90_01655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A6J90_01665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A6J90_01670	COG0483	inositol monophosphate 1-phosphatase activity
A6J90_01675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6J90_01690	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A6J90_01700	COG0083	homoserine kinase activity
A6J90_01720	COG0779	Required for maturation of 30S ribosomal subunits
A6J90_01725	COG1401	restriction endodeoxyribonuclease activity
A6J90_01735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6J90_01740	COG1121	(ABC) transporter
A6J90_01750	COG0840	transmembrane signaling receptor activity
A6J90_01760	COG0492	ferredoxin-NADP+ reductase activity
A6J90_01765	COG3118	belongs to the thioredoxin family
A6J90_01775	COG0460	homoserine dehydrogenase
A6J90_01780	COG0436	Aminotransferase
A6J90_01795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J90_01800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A6J90_01810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A6J90_01830	COG0602	queuosine metabolic process
A6J90_01855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A6J90_01875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A6J90_01905	COG1840	ABC-type Fe3 transport system, periplasmic component
A6J90_01915	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A6J90_01920	COG1253	flavin adenine dinucleotide binding
A6J90_01930	COG2824	Alkylphosphonate utilization operon protein PhnA
A6J90_01935	COG0861	Integral membrane protein TerC family
A6J90_01940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A6J90_01945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A6J90_01945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A6J90_01955	COG0606	chelatase, subunit chli
A6J90_01960	COG0242	peptide deformylase activity
A6J90_01975	COG0302	gtp cyclohydrolase
A6J90_01980	COG1157	protein secretion by the type III secretion system
A6J90_01985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A6J90_01995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A6J90_01995	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A6J90_02025	COG1297	OPT oligopeptide transporter protein
A6J90_02075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A6J90_02080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A6J90_02085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A6J90_02100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J90_02120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A6J90_02125	COG0670	Belongs to the BI1 family
A6J90_02130	COG0288	reversible hydration of carbon dioxide
A6J90_02135	COG0668	transmembrane transport
A6J90_02150	COG2703	oxygen carrier activity
A6J90_02165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A6J90_02195	COG0477	Major facilitator Superfamily
A6J90_02210	COG2921	Belongs to the UPF0250 family
A6J90_02220	COG0708	Exodeoxyribonuclease III
A6J90_02225	COG2194	sulfuric ester hydrolase activity
A6J90_02230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A6J90_02240	COG0418	dihydroorotase activity
A6J90_02250	COG2226	methyltransferase
A6J90_02260	COG0428	transporter
A6J90_02285	COG0330	HflC and HflK could
A6J90_02295	COG1942	4-Oxalocrotonate Tautomerase
A6J90_02300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6J90_02305	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A6J90_02315	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6J90_02320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A6J90_02325	COG1077	Cell shape determining protein MreB Mrl
A6J90_02335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A6J90_02365	COG0835	chemotaxis
A6J90_02370	COG2198	Histidine kinase
A6J90_02370	COG0643	Histidine kinase
A6J90_02375	COG0784	Response regulator, receiver
A6J90_02375	COG0835	chemotaxis
A6J90_02385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6J90_02390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6J90_02430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A6J90_02470	COG4106	trans-aconitate 2-methyltransferase activity
A6J90_02475	COG2830	Protein of unknown function (DUF452)
A6J90_02485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6J90_02495	COG2076	Multidrug Resistance protein
A6J90_02520	COG0019	diaminopimelate decarboxylase activity
A6J90_02535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A6J90_02545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J90_02555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A6J90_02570	COG2226	methyltransferase
A6J90_02575	COG1570	exodeoxyribonuclease VII activity
A6J90_02580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A6J90_02585	COG0251	oxidation-reduction process
A6J90_02590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J90_02595	COG0416	fatty acid biosynthetic process
A6J90_02610	COG0105	UTP biosynthetic process
A6J90_02620	COG0450	alkyl hydroperoxide reductase
A6J90_02625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A6J90_02630	COG1360	Flagellar Motor Protein
A6J90_02635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A6J90_02655	COG1238	metal cluster binding
A6J90_02660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A6J90_02665	COG0730	response to heat
A6J90_02680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A6J90_02680	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J90_02685	COG0135	phosphoribosylanthranilate isomerase activity
A6J90_02705	COG1776	CheC inhibitor of MCP methylation
A6J90_02705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J90_02720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A6J90_02725	COG0745	RESPONSE REGULATOR receiver
A6J90_02745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6J90_02750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A6J90_02760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J90_02770	COG1538	Outer membrane efflux protein
A6J90_02780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J90_02810	COG0754	glutathionylspermidine amidase activity
A6J90_02815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6J90_02835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6J90_02840	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
A6J90_02845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A6J90_02855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6J90_02865	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A6J90_02875	COG1160	GTP binding
A6J90_02885	COG0180	Tryptophanyl-tRNA synthetase
A6J90_02910	COG0579	oxidoreductase
A6J90_02915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A6J90_02970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A6J90_02990	COG1053	succinate dehydrogenase
A6J90_02995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A6J90_03005	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A6J90_03070	COG0488	(ABC) transporter
A6J90_03085	COG1739	Uncharacterized protein family UPF0029
A6J90_03125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A6J90_03145	COG1028	Short-chain dehydrogenase reductase Sdr
A6J90_03155	COG1053	succinate dehydrogenase
A6J90_03160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A6J90_03165	COG2048	Heterodisulfide reductase, subunit B
A6J90_03170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A6J90_03180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6J90_03190	COG4771	TonB-dependent receptor
A6J90_03195	COG0494	nUDIX hydrolase
A6J90_03200	COG0840	transmembrane signaling receptor activity
A6J90_03215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A6J90_03225	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A6J90_03245	COG2121	Domain of unknown function (DUF374)
A6J90_03250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A6J90_03260	COG0195	Participates in both transcription termination and antitermination
A6J90_03270	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A6J90_03275	COG0612	Peptidase, M16
A6J90_03280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A6J90_03285	COG2346	COG2346, Truncated hemoglobins
A6J90_03300	COG0765	amino acid transport
A6J90_03350	COG0250	Participates in transcription elongation, termination and antitermination
A6J90_03365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A6J90_03375	COG0085	RNA polymerase activity
A6J90_03410	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A6J90_03435	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
A6J90_03440	COG0004	ammonium transporteR
A6J90_03450	COG0673	inositol 2-dehydrogenase activity
A6J90_03460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A6J90_03465	COG0424	maF-like protein
A6J90_03475	COG0542	response to heat
A6J90_03480	COG1937	Protein conserved in bacteria
A6J90_03485	COG0793	Belongs to the peptidase S41A family
A6J90_03495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A6J90_03500	COG0047	phosphoribosylformylglycinamidine synthase activity
A6J90_03510	COG0204	Acyl-transferase
A6J90_03520	COG0326	Molecular chaperone. Has ATPase activity
A6J90_03525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J90_03545	COG1677	Flagellar hook-basal body complex protein FliE
A6J90_03550	COG1558	bacterial-type flagellum-dependent cell motility
A6J90_03555	COG1815	bacterial-type flagellum-dependent cell motility
A6J90_03575	COG0039	L-malate dehydrogenase activity
A6J90_03580	COG0045	succinate-CoA ligase (ADP-forming) activity
A6J90_03585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A6J90_03595	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A6J90_03595	COG0674	pyruvate-flavodoxin oxidoreductase activity
A6J90_03600	COG1013	pyruvate-flavodoxin oxidoreductase activity
A6J90_03620	COG0142	geranyltranstransferase activity
A6J90_03630	COG0442	prolyl-tRNA aminoacylation
A6J90_03640	COG0181	hydroxymethylbilane synthase activity
A6J90_03645	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A6J90_03655	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A6J90_03705	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A6J90_03710	COG0492	ferredoxin-NADP+ reductase activity
A6J90_03725	COG0305	Participates in initiation and elongation during chromosome replication
A6J90_03770	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6J90_03770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6J90_03775	COG1610	YqeY-like protein
A6J90_03780	COG0028	Belongs to the TPP enzyme family
A6J90_03785	COG0440	acetolactate synthase activity
A6J90_03790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6J90_03800	COG0805	protein transport
A6J90_03805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A6J90_03810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J90_03820	COG0527	aspartate kinase activity
A6J90_03835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A6J90_03840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A6J90_03855	COG0196	riboflavin kinase activity
A6J90_03875	COG2860	membrane
A6J90_03885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A6J90_03890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J90_03895	COG0191	fructose-bisphosphate aldolase activity
A6J90_03915	COG0733	neurotransmitter:sodium symporter activity
A6J90_03920	COG2258	MOSC domain
A6J90_03925	COG4232	protein-disulfide reductase activity
A6J90_03935	COG1473	amidohydrolase
A6J90_03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J90_03945	COG0577	efflux transmembrane transporter activity
A6J90_03945	COG1136	(ABC) transporter
A6J90_03950	COG1538	Outer membrane efflux protein
A6J90_03965	COG1696	Membrane protein involved in D-alanine export
A6J90_03970	COG1528	Iron-storage protein
A6J90_03975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A6J90_03980	COG0573	inorganic phosphate transmembrane transporter activity
A6J90_03985	COG0581	inorganic phosphate transmembrane transporter activity
A6J90_04005	COG0534	Mate efflux family protein
A6J90_04020	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A6J90_04030	COG0298	carbon dioxide binding
A6J90_04035	COG0409	Hydrogenase expression formation protein
A6J90_04040	COG0309	Hydrogenase expression formation protein (HypE)
A6J90_04045	COG0375	protein maturation
A6J90_04060	COG0557	exoribonuclease II activity
A6J90_04065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A6J90_04075	COG0758	DNA mediated transformation
A6J90_04085	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A6J90_04085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J90_04090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J90_04095	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A6J90_04100	COG0563	adenylate kinase activity
A6J90_04115	COG0497	DNA recombination
A6J90_04120	COG3706	GGDEF domain
A6J90_04120	COG0745	RESPONSE REGULATOR receiver
A6J90_04125	COG0084	hydrolase, TatD family'
A6J90_04130	COG1388	LysM domain
A6J90_04130	COG0791	NLP P60 protein
A6J90_04135	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A6J90_04175	COG3104	oligopeptide transport
A6J90_04180	COG3104	oligopeptide transport
A6J90_04185	COG3104	oligopeptide transport
A6J90_04200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A6J90_04205	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A6J90_04210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A6J90_04215	COG0359	binds to the 23S rRNA
A6J90_04220	COG0137	argininosuccinate synthase activity
A6J90_04225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A6J90_04230	COG0802	atpase or kinase
A6J90_04235	COG1137	ATPase activity
A6J90_04240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A6J90_04245	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A6J90_04295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A6J90_04305	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A6J90_04315	COG0280	phosphate acetyltransferase
A6J90_04340	COG0275	rRNA processing
A6J90_04345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J90_04350	COG0849	cell division
A6J90_04355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A6J90_04360	COG4786	Flagellar basal body rod
A6J90_04365	COG4786	Flagellar basal body rod
A6J90_04370	COG0174	glutamine synthetase
A6J90_04395	COG0752	glycyl-tRNA synthetase alpha subunit
A6J90_04400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A6J90_04410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A6J90_04410	COG1519	Transferase
A6J90_04415	COG0564	pseudouridine synthase activity
A6J90_04420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6J90_04430	COG1837	Belongs to the UPF0109 family
A6J90_04455	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A6J90_04460	COG1393	Belongs to the ArsC family
A6J90_04470	COG0587	DNA-directed DNA polymerase activity
A6J90_04475	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A6J90_04490	COG2890	protein-(glutamine-N5) methyltransferase activity
A6J90_04495	COG0501	Belongs to the peptidase M48B family
A6J90_04505	COG0521	Mo-molybdopterin cofactor biosynthetic process
A6J90_04510	COG0598	Magnesium transport protein CorA
A6J90_04540	COG3842	ATPase activity
A6J90_04620	COG1420	regulation of RNA biosynthetic process
A6J90_04645	COG0732	type I restriction modification DNA specificity domain
A6J90_04670	COG0436	Aminotransferase
A6J90_04675	COG1045	serine acetyltransferase
A6J90_04680	COG1166	arginine decarboxylase activity
A6J90_04690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A6J90_04700	COG0163	prenyltransferase activity
A6J90_04710	COG1464	Belongs to the NlpA lipoprotein family
A6J90_04715	COG1464	Belongs to the NlpA lipoprotein family
A6J90_04720	COG1464	Belongs to the NlpA lipoprotein family
A6J90_04725	COG2011	ABC-type metal ion transport system permease component
A6J90_04730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6J90_04735	COG0525	valine-tRNA ligase activity
A6J90_04745	COG0210	DNA helicase
A6J90_04755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A6J90_04760	COG0243	molybdopterin cofactor binding
A6J90_04765	COG0437	4 iron, 4 sulfur cluster binding
A6J90_04770	COG0348	domain, Protein
A6J90_04775	COG3043	anaerobic respiration
A6J90_04810	COG0788	formyltetrahydrofolate deformylase activity
A6J90_04815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A6J90_04825	COG3852	Histidine kinase
A6J90_04835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6J90_04850	COG1181	Belongs to the D-alanine--D-alanine ligase family
A6J90_04865	COG0728	peptidoglycan biosynthetic process
A6J90_04870	COG0215	cysteine-tRNA ligase activity
A6J90_04875	COG1132	(ABC) transporter
A6J90_04880	COG0167	dihydroorotate dehydrogenase activity
A6J90_04885	COG0612	Peptidase, M16
A6J90_04895	COG1028	Short-chain dehydrogenase reductase Sdr
A6J90_04910	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A6J90_04915	COG1663	tetraacyldisaccharide 4'-kinase activity
A6J90_04920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A6J90_04925	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A6J90_04940	COG1338	Plays a role in the flagellum-specific transport system
A6J90_04960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A6J90_04980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6J90_05000	COG1757	Na H antiporter
A6J90_05005	COG4221	oxidoreductase activity
A6J90_05015	COG1049	propionate catabolic process, 2-methylcitrate cycle
A6J90_05020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6J90_05030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J90_05030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J90_05065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A6J90_05070	COG1408	metallophosphoesterase
A6J90_05075	COG0688	phosphatidylethanolamine metabolic process
A6J90_05120	COG0681	Belongs to the peptidase S26 family
A6J90_05125	COG0303	'Molybdopterin
A6J90_05140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A6J90_05140	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J90_05145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6J90_05150	COG0582	viral genome integration into host DNA
A6J90_05155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A6J90_05160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A6J90_05175	COG3258	Cytochrome c
A6J90_05180	COG3258	Cytochrome c
A6J90_05210	COG2404	hydrolase activity, acting on ester bonds
A6J90_05215	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A6J90_05220	COG1959	2 iron, 2 sulfur cluster binding
A6J90_05230	COG1196	nuclear chromosome segregation
A6J90_05230	COG1674	ftsk spoiiie
A6J90_05235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J90_05255	COG5002	protein histidine kinase activity
A6J90_05260	COG0745	RESPONSE REGULATOR receiver
A6J90_05265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6J90_05275	COG1185	polyribonucleotide nucleotidyltransferase activity
A6J90_05275	COG0539	negative regulation of cytoplasmic translation
A6J90_05290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J90_05290	COG0072	phenylalanine-tRNA ligase activity
A6J90_05300	COG0537	adenosine 5'-monophosphoramidase activity
A6J90_05315	COG0765	amino acid transport
A6J90_05325	COG1115	amino acid carrier protein
A6J90_05330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A6J90_05360	COG1999	signal sequence binding
A6J90_05365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A6J90_05370	COG0776	regulation of translation
A6J90_05380	COG1607	acyl-coa hydrolase
A6J90_05390	COG1966	Carbon starvation protein
A6J90_05395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A6J90_05400	COG0765	amino acid transport
A6J90_05405	COG0765	amino acid transport
A6J90_05410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J90_05415	COG1126	abc transporter atp-binding protein
A6J90_05420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A6J90_05425	COG2201	protein-glutamate methylesterase activity
A6J90_05450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A6J90_05455	COG0012	GTP binding
A6J90_05465	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A6J90_05470	COG5016	pyruvate
A6J90_05470	COG0511	ligase activity, forming carbon-carbon bonds
A6J90_05475	COG0733	neurotransmitter:sodium symporter activity
A6J90_05480	COG0733	neurotransmitter:sodium symporter activity
A6J90_05575	COG0765	amino acid transport
A6J90_05585	COG0653	protein targeting
A6J90_05590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A6J90_05600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A6J90_05615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A6J90_05630	COG0840	transmembrane signaling receptor activity
A6J90_05640	COG0138	bifunctional purine biosynthesis protein purh
A6J90_05645	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A6J90_05665	COG0706	membrane insertase activity
A6J90_05670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A6J90_05695	COG0824	Thioesterase
A6J90_05735	COG0500	methyltransferase
A6J90_05755	COG2195	Cleaves the N-terminal amino acid of tripeptides
A6J90_05760	COG0477	Major facilitator Superfamily
A6J90_05765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J90_05785	COG3022	response to hydroperoxide
A6J90_05790	COG1473	amidohydrolase
A6J90_05795	COG2807	transmembrane transport
A6J90_05820	COG2181	nitrate reductase activity
A6J90_05820	COG0247	lactate metabolic process
A6J90_05825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J90_05835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A6J90_05840	COG0113	porphobilinogen synthase activity
A6J90_05845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6J90_05860	COG2855	membrane
A6J90_05865	COG0583	DNA-binding transcription factor activity
A6J90_05870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A6J90_05890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6J90_05895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A6J90_05940	COG0582	viral genome integration into host DNA
A6J90_06270	COG3501	Rhs element vgr protein
A6J90_06415	COG3501	Rhs element vgr protein
A6J90_06520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6J90_06520	COG1333	cytochrome c biogenesis protein
A6J90_06545	COG0683	leucine binding
A6J90_06570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6J90_06575	COG2204	response regulator
A6J90_06590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A6J90_06630	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
A6J90_06640	COG0439	Biotin carboxylase
A6J90_06645	COG0772	Belongs to the SEDS family
A6J90_06660	COG0352	thiamine-phosphate diphosphorylase activity
A6J90_06665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A6J90_06680	COG2022	thiamine diphosphate biosynthetic process
A6J90_06710	COG1193	negative regulation of DNA recombination
A6J90_06740	COG0516	GMP reductase activity
A6J90_06740	COG0517	IMP dehydrogenase activity
A6J90_06745	COG0154	amidase activity
A6J90_06755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A6J90_06760	COG1058	Belongs to the CinA family
A6J90_06760	COG1546	Belongs to the CinA family
A6J90_06770	COG0778	Nitroreductase
A6J90_06775	COG0778	Nitroreductase
A6J90_06780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A6J90_06785	COG0750	zinc metalloprotease
A6J90_06790	COG2990	Protein conserved in bacteria
A6J90_06810	COG0629	single-stranded DNA binding
A6J90_06820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A6J90_06835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6J90_06880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A6J90_06890	COG0739	heme binding
A6J90_06895	COG0285	dihydrofolate synthase activity
A6J90_06910	COG0495	leucyl-tRNA aminoacylation
A6J90_06915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J90_06920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J90_06925	COG1862	Preprotein translocase
A6J90_06930	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A6J90_06935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A6J90_06940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A6J90_06960	COG0210	DNA helicase
A6J90_06995	COG0542	response to heat
A6J90_07010	COG2095	MarC family integral membrane protein
A6J90_07015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J90_07020	COG2833	Protein of unknown function (DUF455)
A6J90_07025	COG1183	phosphatidylcholine synthase activity
A6J90_07035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6J90_07040	COG2264	protein methyltransferase activity
A6J90_07055	COG1086	Polysaccharide biosynthesis protein
A6J90_07060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A6J90_07065	COG0110	maltose O-acetyltransferase activity
A6J90_07070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A6J90_07075	COG0438	transferase activity, transferring glycosyl groups
A6J90_07080	COG1287	oligosaccharyl transferase activity
A6J90_07085	COG0438	transferase activity, transferring glycosyl groups
A6J90_07090	COG1215	transferase activity, transferring glycosyl groups
A6J90_07095	COG0438	transferase activity, transferring glycosyl groups
A6J90_07100	COG1132	(ABC) transporter
A6J90_07105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J90_07115	COG0859	PFAM glycosyl transferase family 9
A6J90_07120	COG1560	Kdo2-lipid A biosynthetic process
A6J90_07125	COG0463	Glycosyl transferase, family 2
A6J90_07130	COG1216	Glycosyl transferase, family 2
A6J90_07130	COG1442	glycosyl transferase family 8
A6J90_07155	COG2089	acid synthase
A6J90_07175	COG0110	maltose O-acetyltransferase activity
A6J90_07180	COG1216	Glycosyl transferase, family 2
A6J90_07200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A6J90_07200	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A6J90_07210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A6J90_07225	COG2217	Heavy metal translocating P-type atpase
A6J90_07230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A6J90_07235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A6J90_07240	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A6J90_07245	COG2217	Heavy metal translocating P-type atpase
A6J90_07265	COG3610	response to peptide
A6J90_07275	COG0039	L-malate dehydrogenase activity
A6J90_07280	COG0586	Pfam SNARE associated Golgi protein
A6J90_07295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A6J90_07300	COG0217	transcriptional regulatory protein
A6J90_07315	COG0018	arginyl-trna synthetase
A6J90_07325	COG0194	GDP metabolic process
A6J90_07335	COG1684	flagellar biosynthetic protein fliR
A6J90_07345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A6J90_07355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A6J90_07365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A6J90_07370	COG0723	plastoquinol--plastocyanin reductase activity
A6J90_07375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A6J90_07400	COG1301	dicarboxylic acid transport
A6J90_07420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A6J90_07425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A6J90_07430	COG1854	S-ribosylhomocysteine lyase activity
A6J90_07450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A6J90_07460	COG0356	it plays a direct role in the translocation of protons across the membrane
A6J90_07465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A6J90_07470	COG0552	protein localization to endoplasmic reticulum
A6J90_07500	COG1295	ribonuclease BN
A6J90_07505	COG0277	FAD linked oxidase domain protein
A6J90_07515	COG0739	heme binding
A6J90_07555	COG0745	RESPONSE REGULATOR receiver
A6J90_07575	COG5002	protein histidine kinase activity
A6J90_07580	COG0745	RESPONSE REGULATOR receiver
A6J90_07585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6J90_07590	COG0484	heat shock protein binding
A6J90_07595	COG0789	Transcriptional regulator
A6J90_07615	COG0751	glycine-tRNA ligase activity
A6J90_07620	COG0739	heme binding
A6J90_07635	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A6J90_07650	COG2814	Major facilitator Superfamily
A6J90_07665	COG0731	radical SAM domain protein
A6J90_07675	COG0322	excinuclease ABC activity
A6J90_07695	COG0151	Belongs to the GarS family
A6J90_07720	COG1942	4-Oxalocrotonate Tautomerase
A6J90_07735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A6J90_07740	COG4773	Receptor
A6J90_07745	COG0484	heat shock protein binding
A6J90_07750	COG0745	RESPONSE REGULATOR receiver
A6J90_07760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A6J90_07765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A6J90_07770	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
A6J90_07775	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A6J90_07780	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A6J90_07800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A6J90_07805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A6J90_07830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6J90_07845	COG0564	pseudouridine synthase activity
A6J90_07850	COG0772	Belongs to the SEDS family
A6J90_07865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J90_07870	COG0569	domain protein
A6J90_07875	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A6J90_07885	COG0281	malic enzyme
A6J90_07885	COG0280	phosphate acetyltransferase
A6J90_07890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A6J90_07900	COG0439	Biotin carboxylase
A6J90_07905	COG0511	ligase activity, forming carbon-carbon bonds
A6J90_07915	COG1086	Polysaccharide biosynthesis protein
A6J90_07920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A6J90_07955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J90_08000	COG1083	cytidylyl-transferase
A6J90_08005	COG3980	spore coat polysaccharide biosynthesis protein
A6J90_08010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J90_08015	COG0107	imidazoleglycerol-phosphate synthase activity
A6J90_08030	COG2089	acid synthase
A6J90_08045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J90_08050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A6J90_08080	COG2089	acid synthase
A6J90_08085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A6J90_08090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A6J90_08100	COG1083	cytidylyl-transferase
A6J90_08105	COG1028	Short-chain dehydrogenase reductase Sdr
A6J90_08130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J90_08135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J90_08155	COG2165	general secretion pathway protein
A6J90_08160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A6J90_08170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A6J90_08175	COG0575	Belongs to the CDS family
A6J90_08190	COG0746	molybdenum cofactor guanylyltransferase activity
A6J90_08195	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
A6J90_08200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J90_08205	COG4605	iron ion homeostasis
A6J90_08210	COG4604	ABC transporter, ATP-binding protein
A6J90_08215	COG4607	ABC-type enterochelin transport system periplasmic component
A6J90_08230	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A6J90_08235	COG3005	denitrification pathway
A6J90_08280	COG0628	permease
A6J90_08285	COG0114	fumarate hydratase activity
A6J90_08295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A6J90_08305	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A6J90_08310	COG2252	PERMEase
A6J90_08320	COG2853	Lipoprotein
A6J90_08340	COG2814	Major facilitator Superfamily
A6J90_08375	COG0716	FMN binding
A6J90_08390	COG0753	catalase activity
A6J90_08400	COG2964	Protein conserved in bacteria
A6J90_08405	COG0251	oxidation-reduction process
A6J90_08410	COG3069	C4-dicarboxylate transmembrane transporter activity
A6J90_08415	COG3069	C4-dicarboxylate transmembrane transporter activity
A6J90_08420	COG3069	C4-dicarboxylate transmembrane transporter activity
A6J90_08445	COG1918	ferrous iron import across plasma membrane
A6J90_08450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A6J90_08455	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A6J90_08460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A6J90_08475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A6J90_08500	COG1580	Controls the rotational direction of flagella during chemotaxis
A6J90_08515	COG2124	cytochrome p450
A6J90_08535	COG0529	Catalyzes the synthesis of activated sulfate
A6J90_08540	COG1213	nucleotidyl transferase
A6J90_08545	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A6J90_08550	COG0574	Belongs to the PEP-utilizing enzyme family
A6J90_08550	COG3848	Pyruvate phosphate dikinase
A6J90_08555	COG2226	methyltransferase
A6J90_08575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A6J90_08595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J90_08615	COG1442	glycosyl transferase family 8
A6J90_08615	COG1216	Glycosyl transferase, family 2
A6J90_08620	COG1442	glycosyl transferase family 8
A6J90_08620	COG1216	Glycosyl transferase, family 2
A6J90_08625	COG1442	glycosyl transferase family 8
A6J90_08635	COG3562	capsule polysaccharide
A6J90_08640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A6J90_08640	COG0517	IMP dehydrogenase activity
A6J90_08715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A6J90_08785	COG3951	Flagellar rod assembly protein muramidase FlgJ
A6J90_08810	COG0730	response to heat
A6J90_08815	COG1459	type II secretion system
A6J90_08850	COG0546	phosphoglycolate phosphatase activity
A6J90_08865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A6J90_08870	COG0210	DNA helicase
A6J90_08875	COG2887	Belongs to the helicase family. UvrD subfamily
A6J90_08920	COG0745	RESPONSE REGULATOR receiver
A6J90_08935	COG0505	Belongs to the CarA family
A6J90_08970	COG0425	Belongs to the sulfur carrier protein TusA family
A6J90_08995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A6J90_09025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A6J90_09035	COG0437	4 iron, 4 sulfur cluster binding
A6J90_09070	COG0314	molybdopterin synthase activity
A6J90_09075	COG0303	'Molybdopterin
A6J90_09080	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A6J90_09090	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
A6J90_09115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A6J90_09130	COG2992	FlgJ-related protein
A6J90_09140	COG0783	Belongs to the Dps family
A6J90_09145	COG0166	Belongs to the GPI family
A6J90_09160	COG3839	Belongs to the ABC transporter superfamily
A6J90_09165	COG4662	Binding-protein-dependent transport system inner membrane component
A6J90_09170	COG2998	abc-type tungstate transport system, permease component
A6J90_09180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A6J90_09195	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J90_09200	COG1733	regulation of RNA biosynthetic process