IM45_153 281d04716dd73ddd6de0d9577dd47df5 531 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 21 505 22.703 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 IM45_153 281d04716dd73ddd6de0d9577dd47df5 531 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 74 466 1.2E-103 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 IM45_153 281d04716dd73ddd6de0d9577dd47df5 531 SUPERFAMILY SSF56317 232 497 6.67E-32 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily IM45_153 281d04716dd73ddd6de0d9577dd47df5 531 Pfam PF00795 Carbon-nitrogen hydrolase 234 484 1.5E-31 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 SUPERFAMILY SSF52402 151 405 4.41E-57 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 Pfam PF02540 NAD synthase 181 212 1.6E-5 T 12-10-2018 IPR022310 NAD/GMP synthase IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 Gene3D G3DSA:3.40.50.620 167 364 2.2E-73 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 Gene3D G3DSA:3.40.50.880 1 164 2.9E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 PRINTS PR00097 Anthranilate synthase component II signature 11 20 7.8E-7 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 PRINTS PR00097 Anthranilate synthase component II signature 135 148 7.8E-7 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 PRINTS PR00097 Anthranilate synthase component II signature 38 49 7.8E-7 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 SUPERFAMILY SSF54810 364 484 1.44E-48 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 162 2.6E-58 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 484 48.119 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 Pfam PF00117 Glutamine amidotransferase class-I 7 158 3.2E-29 T 12-10-2018 IPR017926 Glutamine amidotransferase IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 SUPERFAMILY SSF52317 5 195 2.47E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 Gene3D G3DSA:3.30.300.10 365 484 2.9E-49 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 Pfam PF00958 GMP synthase C terminal domain 392 483 1.0E-41 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 174 484 8.5E-148 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 PRINTS PR00096 Glutamine amidotransferase superfamily signature 135 148 3.9E-8 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 PRINTS PR00096 Glutamine amidotransferase superfamily signature 11 20 3.9E-8 T 12-10-2018 IM45_1427 758beeac5015c7da3fd4b833e0441eae 484 PRINTS PR00096 Glutamine amidotransferase superfamily signature 38 49 3.9E-8 T 12-10-2018 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 1 376 30.865 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 1 372 4.1E-132 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 Gene3D G3DSA:3.30.460.10 1 125 6.2E-50 T 12-10-2018 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 Gene3D G3DSA:1.10.3090.10 126 375 1.4E-93 T 12-10-2018 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 Pfam PF12626 Polymerase A arginine-rich C-terminus 274 373 3.1E-32 T 12-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 SUPERFAMILY SSF81301 1 124 1.96E-34 T 12-10-2018 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 155 214 2.8E-20 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 SUPERFAMILY SSF81891 126 337 2.22E-47 T 12-10-2018 IM45_527 b22f306ea4e1097a7ce93a0c45dbe35b 385 Pfam PF01743 Poly A polymerase head domain 1 128 8.0E-37 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 IM45_956 49346b73291772320f2cf0e59173f4e3 115 Gene3D G3DSA:3.30.428.10 1 115 5.4E-30 T 12-10-2018 IPR036265 HIT-like superfamily IM45_956 49346b73291772320f2cf0e59173f4e3 115 Pfam PF01230 HIT domain 15 109 1.9E-24 T 12-10-2018 IPR001310 Histidine triad (HIT) protein IM45_956 49346b73291772320f2cf0e59173f4e3 115 SUPERFAMILY SSF54197 1 112 9.43E-30 T 12-10-2018 IPR036265 HIT-like superfamily IM45_956 49346b73291772320f2cf0e59173f4e3 115 PRINTS PR00332 Histidine triad family signature 95 105 1.2E-12 T 12-10-2018 IPR001310 Histidine triad (HIT) protein IM45_956 49346b73291772320f2cf0e59173f4e3 115 PRINTS PR00332 Histidine triad family signature 27 45 1.2E-12 T 12-10-2018 IPR001310 Histidine triad (HIT) protein IM45_956 49346b73291772320f2cf0e59173f4e3 115 PRINTS PR00332 Histidine triad family signature 6 22 1.2E-12 T 12-10-2018 IPR001310 Histidine triad (HIT) protein IM45_956 49346b73291772320f2cf0e59173f4e3 115 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 12-10-2018 IPR019808 Histidine triad, conserved site IM45_843 cdb69d598f45daa4469ca5a971a7bcbd 180 Pfam PF12838 4Fe-4S dicluster domain 59 113 2.0E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain IM45_843 cdb69d598f45daa4469ca5a971a7bcbd 180 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 7 147 24.959 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_843 cdb69d598f45daa4469ca5a971a7bcbd 180 Gene3D G3DSA:3.30.70.3270 33 173 7.4E-41 T 12-10-2018 IM45_843 cdb69d598f45daa4469ca5a971a7bcbd 180 SUPERFAMILY SSF54862 38 157 4.19E-26 T 12-10-2018 IM45_843 cdb69d598f45daa4469ca5a971a7bcbd 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site IM45_843 cdb69d598f45daa4469ca5a971a7bcbd 180 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 16 137 4.2E-46 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_313 792c3a1d4c6ccb30341255d2b4f41c69 54 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 39 1.0E-12 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_313 792c3a1d4c6ccb30341255d2b4f41c69 54 Pfam PF00468 Ribosomal protein L34 1 44 1.5E-22 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_313 792c3a1d4c6ccb30341255d2b4f41c69 54 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.677 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_313 792c3a1d4c6ccb30341255d2b4f41c69 54 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.3E-24 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_313 792c3a1d4c6ccb30341255d2b4f41c69 54 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 SUPERFAMILY SSF52374 110 454 1.03E-89 T 12-10-2018 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 SUPERFAMILY SSF55190 2 96 5.36E-18 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 87 8.2E-18 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 576 1.1E-184 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 Gene3D G3DSA:3.40.50.620 109 453 1.1E-103 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 576 27.043 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 4.7E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 4.7E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 4.7E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 4.7E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 Pfam PF05746 DALR anticodon binding domain 460 576 1.7E-31 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 SMART SM00836 460 576 4.3E-31 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 Gene3D G3DSA:1.10.730.10 454 576 3.6E-30 T 12-10-2018 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 SMART SM01016 5 87 1.3E-22 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 Pfam PF00750 tRNA synthetases class I (R) 107 446 7.3E-147 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 SUPERFAMILY SSF47323 454 576 2.03E-33 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_635 f0398c5c6ce74d4c359b7f5924cba80d 576 Gene3D G3DSA:3.30.1360.70 1 106 1.4E-29 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 IM45_003 a742d2438a90643727ed4bba70660d1d 152 Pfam PF14437 MafB19-like deaminase 9 147 6.6E-27 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 IM45_003 a742d2438a90643727ed4bba70660d1d 152 SUPERFAMILY SSF53927 3 149 6.36E-48 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 IM45_003 a742d2438a90643727ed4bba70660d1d 152 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 13 149 40.386 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 IM45_003 a742d2438a90643727ed4bba70660d1d 152 Gene3D G3DSA:3.40.140.10 2 152 9.2E-52 T 12-10-2018 IM45_003 a742d2438a90643727ed4bba70660d1d 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 95 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 SUPERFAMILY SSF53067 187 382 4.28E-67 T 12-10-2018 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 Gene3D G3DSA:3.90.640.10 229 316 6.5E-170 T 12-10-2018 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 600 3.3E-287 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 Gene3D G3DSA:2.60.34.10 383 523 1.8E-65 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 Gene3D G3DSA:3.30.420.40 180 366 6.5E-170 T 12-10-2018 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 Pfam PF00012 Hsp70 protein 4 600 2.7E-262 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 SUPERFAMILY SSF53067 4 183 2.89E-65 T 12-10-2018 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 630 36.356 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 Gene3D G3DSA:1.20.1270.10 524 603 2.0E-23 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 469 485 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 198 208 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 334 350 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 388 407 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 PRINTS PR00301 70kDa heat shock protein signature 365 385 2.8E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 SUPERFAMILY SSF100920 384 540 6.15E-60 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 Gene3D G3DSA:3.30.420.40 5 379 6.5E-170 T 12-10-2018 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 IM45_1217 dfcf7adf6f9bacdd134b9c5c80f53428 634 SUPERFAMILY SSF100934 535 598 6.67E-5 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 IM45_1203 240f7f123d19774aedfea08743896dbe 264 Pfam PF00303 Thymidylate synthase 2 264 8.4E-117 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 12-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 37.783 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 SUPERFAMILY SSF55831 1 264 2.62E-120 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 Gene3D G3DSA:3.30.572.10 1 264 2.7E-123 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 264 2.3E-86 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 2.1E-37 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 7.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 7.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 7.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 7.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1203 240f7f123d19774aedfea08743896dbe 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 7.3E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 IM45_1357 02b6e7313e0eff5d57a8a7db114c37ee 269 Pfam PF02673 Bacitracin resistance protein BacA 10 259 2.0E-81 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 IM45_1357 02b6e7313e0eff5d57a8a7db114c37ee 269 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 259 5.0E-89 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 IM45_1357 02b6e7313e0eff5d57a8a7db114c37ee 269 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 267 17.653 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 IM45_825 227daab82546ce88f6aebc6767117c91 427 Pfam PF08245 Mur ligase middle domain 58 197 7.6E-7 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 IM45_825 227daab82546ce88f6aebc6767117c91 427 Gene3D G3DSA:3.40.1190.10 3 291 2.8E-86 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_825 227daab82546ce88f6aebc6767117c91 427 Gene3D G3DSA:3.90.190.20 292 423 5.8E-31 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_825 227daab82546ce88f6aebc6767117c91 427 SUPERFAMILY SSF53623 17 288 1.56E-80 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_825 227daab82546ce88f6aebc6767117c91 427 TIGRFAM TIGR01499 folC: bifunctional protein FolC 36 422 4.8E-95 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 IM45_825 227daab82546ce88f6aebc6767117c91 427 SUPERFAMILY SSF53244 290 422 1.83E-27 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_825 227daab82546ce88f6aebc6767117c91 427 PIRSF PIRSF001563 10 426 8.2E-102 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 IM45_825 227daab82546ce88f6aebc6767117c91 427 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 56 79 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 IM45_825 227daab82546ce88f6aebc6767117c91 427 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 148 163 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 Pfam PF07687 Peptidase dimerisation domain 180 282 2.3E-13 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 Gene3D G3DSA:3.30.70.360 182 295 1.2E-93 T 12-10-2018 IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 SUPERFAMILY SSF55031 183 290 2.62E-17 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 SUPERFAMILY SSF53187 5 373 1.07E-43 T 12-10-2018 IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 138 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 6 373 4.2E-135 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 Pfam PF01546 Peptidase family M20/M25/M40 62 373 2.0E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 3 377 41.977 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 IM45_173 82ebb6306e3ee10b2a55ab16d1fde630 377 Gene3D G3DSA:3.40.630.10 8 363 1.2E-93 T 12-10-2018 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Gene3D G3DSA:3.30.1490.20 123 190 2.5E-24 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Gene3D G3DSA:3.30.470.20 191 329 2.5E-56 T 12-10-2018 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 40.859 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 331 421 2.4E-27 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Gene3D G3DSA:3.40.50.20 2 95 2.4E-35 T 12-10-2018 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 102 1.8E-33 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 1.6E-77 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 Gene3D G3DSA:3.90.600.10 330 423 2.1E-31 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 SMART SM01210 330 423 1.7E-49 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 SUPERFAMILY SSF56059 104 326 5.13E-61 T 12-10-2018 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 SUPERFAMILY SSF52440 2 103 9.35E-34 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 SUPERFAMILY SSF51246 329 422 2.83E-30 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 422 8.4E-170 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_097 656d9ceb29ad3620f177c425536d8a8e 427 SMART SM01209 103 296 5.6E-129 T 12-10-2018 IM45_499 12ae840092b8a83e89728554e85e6816 469 Pfam PF13241 Putative NAD(P)-binding 14 123 4.0E-29 T 12-10-2018 IM45_499 12ae840092b8a83e89728554e85e6816 469 Gene3D G3DSA:3.40.50.720 9 120 3.6E-33 T 12-10-2018 IM45_499 12ae840092b8a83e89728554e85e6816 469 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 303 336 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 Pfam PF14824 Sirohaem biosynthesis protein central 132 154 8.1E-8 T 12-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 Hamap MF_01646 Siroheme synthase [cysG]. 9 465 51.237 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 Gene3D G3DSA:1.10.8.210 158 220 2.4E-13 T 12-10-2018 IPR037115 Sirohaem synthase, dimerisation domain superfamily GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 SUPERFAMILY SSF75615 122 217 5.89E-27 T 12-10-2018 IM45_499 12ae840092b8a83e89728554e85e6816 469 PIRSF PIRSF036426 9 469 1.2E-203 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 Gene3D G3DSA:3.40.1010.10 221 338 7.4E-45 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 IM45_499 12ae840092b8a83e89728554e85e6816 469 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 12 215 4.4E-78 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 Pfam PF10414 Sirohaem synthase dimerisation region 159 215 2.1E-19 T 12-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 Gene3D G3DSA:3.30.160.110 121 156 5.4E-18 T 12-10-2018 IM45_499 12ae840092b8a83e89728554e85e6816 469 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 225 434 9.5E-48 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 IM45_499 12ae840092b8a83e89728554e85e6816 469 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 223 456 9.8E-92 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 SUPERFAMILY SSF53790 220 463 4.84E-77 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 IM45_499 12ae840092b8a83e89728554e85e6816 469 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 228 242 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 IM45_499 12ae840092b8a83e89728554e85e6816 469 SUPERFAMILY SSF51735 10 121 4.86E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_499 12ae840092b8a83e89728554e85e6816 469 Gene3D G3DSA:3.30.950.10 339 468 4.3E-45 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 IM45_1239 78320fafcc2572baea57ccb0fc854630 114 Pfam PF04379 ApaG domain 28 90 1.0E-11 T 12-10-2018 IPR007474 ApaG domain IM45_1239 78320fafcc2572baea57ccb0fc854630 114 Gene3D G3DSA:2.60.40.1470 2 114 7.2E-18 T 12-10-2018 IPR036767 ApaG domain superfamily IM45_1239 78320fafcc2572baea57ccb0fc854630 114 SUPERFAMILY SSF110069 15 114 2.75E-21 T 12-10-2018 IPR036767 ApaG domain superfamily IM45_1087 046b7bb9b0b4b0907cd74aba06bebd98 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.3E-62 T 12-10-2018 IPR023798 Ribosomal protein S7 domain IM45_1087 046b7bb9b0b4b0907cd74aba06bebd98 156 SUPERFAMILY SSF47973 12 156 2.88E-57 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily IM45_1087 046b7bb9b0b4b0907cd74aba06bebd98 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.657 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 IM45_1087 046b7bb9b0b4b0907cd74aba06bebd98 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.0E-68 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 IM45_1087 046b7bb9b0b4b0907cd74aba06bebd98 156 PIRSF PIRSF002122 2 156 3.5E-63 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 IM45_1087 046b7bb9b0b4b0907cd74aba06bebd98 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_1087 046b7bb9b0b4b0907cd74aba06bebd98 156 Gene3D G3DSA:1.10.455.10 2 155 1.0E-61 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily IM45_984 33cd641a247c36d26eda9a43840d6645 622 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 607 1.9E-203 T 12-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 IM45_984 33cd641a247c36d26eda9a43840d6645 622 Gene3D G3DSA:3.40.1750.10 187 506 2.2E-156 T 12-10-2018 IM45_984 33cd641a247c36d26eda9a43840d6645 622 Gene3D G3DSA:3.90.226.10 327 549 2.2E-156 T 12-10-2018 IM45_984 33cd641a247c36d26eda9a43840d6645 622 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 335 548 1.9E-50 T 12-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 IM45_984 33cd641a247c36d26eda9a43840d6645 622 Gene3D G3DSA:3.90.226.10 95 316 2.2E-156 T 12-10-2018 IM45_984 33cd641a247c36d26eda9a43840d6645 622 SUPERFAMILY SSF52096 34 285 6.81E-28 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily IM45_984 33cd641a247c36d26eda9a43840d6645 622 Pfam PF01343 Peptidase family S49 401 550 7.4E-45 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 IM45_984 33cd641a247c36d26eda9a43840d6645 622 Pfam PF01343 Peptidase family S49 139 290 4.8E-33 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 IM45_984 33cd641a247c36d26eda9a43840d6645 622 PIRSF PIRSF001217 8 614 1.7E-204 T 12-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 IM45_984 33cd641a247c36d26eda9a43840d6645 622 SUPERFAMILY SSF52096 332 538 1.6E-39 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily IM45_996 0d9402730ec214bd23827f879856c183 231 SUPERFAMILY SSF53067 5 107 2.2E-28 T 12-10-2018 IM45_996 0d9402730ec214bd23827f879856c183 231 SUPERFAMILY SSF53067 111 220 7.12E-23 T 12-10-2018 IM45_996 0d9402730ec214bd23827f879856c183 231 Gene3D G3DSA:3.30.420.40 96 191 6.9E-74 T 12-10-2018 IM45_996 0d9402730ec214bd23827f879856c183 231 Pfam PF00814 Glycoprotease family 32 155 8.9E-27 T 12-10-2018 IPR000905 Gcp-like domain IM45_996 0d9402730ec214bd23827f879856c183 231 Gene3D G3DSA:3.30.420.40 5 225 6.9E-74 T 12-10-2018 IM45_996 0d9402730ec214bd23827f879856c183 231 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 222 7.1E-60 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 5.2E-23 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 PIRSF PIRSF001529 1 430 2.6E-170 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 322 335 8.5E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 339 355 8.5E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 8.5E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 282 295 8.5E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 270 282 8.5E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 428 39.134 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 SUPERFAMILY SSF55681 114 424 6.02E-94 T 12-10-2018 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 Gene3D G3DSA:3.30.930.10 105 430 1.5E-109 T 12-10-2018 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 230 406 4.1E-32 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 SUPERFAMILY SSF46589 1 112 8.37E-24 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 Gene3D G3DSA:1.10.287.40 1 104 5.4E-15 T 12-10-2018 IM45_729 043e2db1f9bd2c9a4eff1d71b1a9dd8d 430 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 423 2.9E-161 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 SUPERFAMILY SSF52540 186 448 7.72E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 Gene3D G3DSA:3.40.50.300 186 357 5.9E-46 T 12-10-2018 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 PIRSF PIRSF006485 1 450 1.2E-170 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 441 2.8E-170 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 362 441 9.7E-25 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 Gene3D G3DSA:3.30.300.20 362 443 1.5E-18 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.6E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 2.6E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 SMART SM00382 185 300 0.48 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 SMART SM00382 1 138 3.4 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 Gene3D G3DSA:3.40.50.300 2 159 1.1E-43 T 12-10-2018 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 Hamap MF_00195 GTPase Der [der]. 2 445 36.971 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 187 353 8.5E-19 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 156 5.8E-23 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 SUPERFAMILY SSF52540 4 166 2.95E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 Pfam PF01926 50S ribosome-binding GTPase 5 119 2.1E-27 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_019 9d903ed5560abebd4a76307bbc1f3421 472 Pfam PF01926 50S ribosome-binding GTPase 189 306 1.2E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 360 374 4.1E-31 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 345 359 4.1E-31 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 286 308 4.1E-31 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 424 437 4.1E-31 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 58 77 4.1E-31 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 Gene3D G3DSA:3.40.710.10 20 84 3.2E-6 T 12-10-2018 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 Gene3D G3DSA:3.40.710.10 251 479 7.4E-57 T 12-10-2018 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 Gene3D G3DSA:3.50.80.20 85 182 3.9E-17 T 12-10-2018 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 SUPERFAMILY SSF56601 26 459 3.64E-93 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like IM45_1401 52c110f55f1c5afb89635043d609fe54 479 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 47 447 1.2E-143 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_1401 52c110f55f1c5afb89635043d609fe54 479 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 22 467 1.0E-136 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_309 f650223ba53f27039934915db0f847ec 433 Pfam PF00308 Bacterial dnaA protein 99 314 1.2E-93 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA IM45_309 f650223ba53f27039934915db0f847ec 433 SUPERFAMILY SSF48295 329 432 3.66E-37 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 IM45_309 f650223ba53f27039934915db0f847ec 433 Pfam PF11638 DnaA N-terminal domain 4 64 9.4E-20 T 12-10-2018 IPR024633 DnaA N-terminal domain IM45_309 f650223ba53f27039934915db0f847ec 433 SUPERFAMILY SSF52540 99 309 4.66E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_309 f650223ba53f27039934915db0f847ec 433 ProSitePatterns PS01008 DnaA protein signature. 391 410 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 IM45_309 f650223ba53f27039934915db0f847ec 433 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 342 410 3.5E-31 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 IM45_309 f650223ba53f27039934915db0f847ec 433 SMART SM00382 130 261 3.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_309 f650223ba53f27039934915db0f847ec 433 SMART SM00760 341 410 2.5E-43 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 IM45_309 f650223ba53f27039934915db0f847ec 433 Gene3D G3DSA:1.10.1750.10 340 433 5.6E-37 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 IM45_309 f650223ba53f27039934915db0f847ec 433 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 430 2.4E-172 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 IM45_309 f650223ba53f27039934915db0f847ec 433 Gene3D G3DSA:1.10.8.60 264 334 2.7E-21 T 12-10-2018 IM45_309 f650223ba53f27039934915db0f847ec 433 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 131 151 2.0E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like IM45_309 f650223ba53f27039934915db0f847ec 433 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 163 177 2.0E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like IM45_309 f650223ba53f27039934915db0f847ec 433 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 195 209 2.0E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like IM45_309 f650223ba53f27039934915db0f847ec 433 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 229 256 2.0E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like IM45_309 f650223ba53f27039934915db0f847ec 433 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 391 410 2.0E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like IM45_309 f650223ba53f27039934915db0f847ec 433 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 432 32.918 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 IM45_309 f650223ba53f27039934915db0f847ec 433 Gene3D G3DSA:3.40.50.300 100 262 4.4E-47 T 12-10-2018 IM45_309 f650223ba53f27039934915db0f847ec 433 Gene3D G3DSA:3.30.300.180 2 99 3.9E-36 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 SUPERFAMILY SSF54211 221 391 1.18E-61 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 SUPERFAMILY SSF55874 4 219 8.91E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 801 103.929 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 731 790 9.0E-29 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 SUPERFAMILY SSF56719 394 794 3.66E-84 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 801 1.3E-304 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Pfam PF00204 DNA gyrase B 221 390 2.0E-59 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Gene3D G3DSA:3.30.565.10 1 220 1.8E-93 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 268 281 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 70 83 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 420 434 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 487 503 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 505 522 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 525 537 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 113 127 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 35 50 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR00418 DNA topoisomerase II family signature 733 749 1.8E-70 T 12-10-2018 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 470 479 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 360 374 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 754 766 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 181 196 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 374 394 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 196 209 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 770 786 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 5 15 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 220 242 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 PRINTS PR01159 DNA gyrase subunit B signature 312 328 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Gene3D G3DSA:3.40.50.670 679 799 5.0E-26 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Gene3D G3DSA:3.40.50.670 398 572 2.2E-73 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Gene3D G3DSA:3.30.230.10 221 392 1.1E-73 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Pfam PF01751 Toprim domain 419 531 7.5E-18 T 12-10-2018 IPR006171 TOPRIM domain IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 173 3.8E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 SMART SM00387 31 175 1.8E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 ProSitePatterns PS00177 DNA topoisomerase II signature. 422 430 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 SMART SM00433 35 605 1.9E-266 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 IM45_305 efd26bb54e9f0f5f97c8d451a02061af 801 Gene3D G3DSA:3.10.20.690 590 678 3.4E-28 T 12-10-2018 IM45_1381 ac4fceb8fb7e4c4f0cb668baf09f199b 132 Gene3D G3DSA:3.30.300.20 1 109 1.8E-33 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta IM45_1381 ac4fceb8fb7e4c4f0cb668baf09f199b 132 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 116 2.7E-34 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 IM45_1381 ac4fceb8fb7e4c4f0cb668baf09f199b 132 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 6 114 24.434 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 IM45_1381 ac4fceb8fb7e4c4f0cb668baf09f199b 132 Pfam PF02033 Ribosome-binding factor A 7 113 1.1E-26 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 IM45_1381 ac4fceb8fb7e4c4f0cb668baf09f199b 132 ProSitePatterns PS01319 Ribosome-binding factor A signature. 80 101 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 IM45_1381 ac4fceb8fb7e4c4f0cb668baf09f199b 132 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 101 2.0E-32 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 IM45_1381 ac4fceb8fb7e4c4f0cb668baf09f199b 132 SUPERFAMILY SSF89919 2 108 4.84E-29 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 304 359 3.5E-8 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 SUPERFAMILY SSF53244 302 439 1.69E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 SUPERFAMILY SSF53623 95 300 9.03E-49 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 Gene3D G3DSA:3.40.1190.10 94 302 1.4E-63 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 SUPERFAMILY SSF51984 3 94 1.06E-20 T 12-10-2018 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 Gene3D G3DSA:3.90.190.20 303 437 2.4E-41 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 440 32.078 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 Pfam PF08245 Mur ligase middle domain 110 283 2.5E-24 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 Gene3D G3DSA:3.40.50.720 2 93 4.9E-24 T 12-10-2018 IM45_1143 db195945d50f7ee1a6d5450323f6e656 449 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 438 2.1E-121 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_1293 d51ad587dc09ac1198e499289379a654 188 SMART SM00841 131 186 1.0E-31 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 IM45_1293 d51ad587dc09ac1198e499289379a654 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site IM45_1293 d51ad587dc09ac1198e499289379a654 188 PIRSF PIRSF005901 2 188 1.8E-61 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP IM45_1293 d51ad587dc09ac1198e499289379a654 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 73 123 1.4E-14 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 IM45_1293 d51ad587dc09ac1198e499289379a654 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 6 62 6.2E-24 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like IM45_1293 d51ad587dc09ac1198e499289379a654 188 SMART SM01185 69 123 8.5E-13 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 IM45_1293 d51ad587dc09ac1198e499289379a654 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 44.797 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 IM45_1293 d51ad587dc09ac1198e499289379a654 188 SUPERFAMILY SSF50104 2 63 1.5E-20 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily IM45_1293 d51ad587dc09ac1198e499289379a654 188 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 1.9E-73 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 IM45_1293 d51ad587dc09ac1198e499289379a654 188 Gene3D G3DSA:2.40.50.140 130 188 3.3E-27 T 12-10-2018 IM45_1293 d51ad587dc09ac1198e499289379a654 188 SUPERFAMILY SSF50249 130 187 1.88E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1293 d51ad587dc09ac1198e499289379a654 188 Gene3D G3DSA:2.30.30.30 1 65 4.2E-26 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 IM45_1293 d51ad587dc09ac1198e499289379a654 188 SUPERFAMILY SSF50249 71 128 1.37E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1293 d51ad587dc09ac1198e499289379a654 188 Gene3D G3DSA:2.40.50.140 66 127 5.7E-22 T 12-10-2018 IM45_1293 d51ad587dc09ac1198e499289379a654 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 2.0E-25 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Gene3D G3DSA:2.40.50.140 6 98 2.1E-15 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SUPERFAMILY SSF50249 190 277 5.3E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PIRSF PIRSF002111 1 532 1.2E-210 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SUPERFAMILY SSF50249 255 356 1.34E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SUPERFAMILY SSF50249 2 112 1.48E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Pfam PF00575 S1 RNA binding domain 191 260 1.2E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Pfam PF00575 S1 RNA binding domain 275 347 1.5E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Pfam PF00575 S1 RNA binding domain 104 171 3.1E-10 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Pfam PF00575 S1 RNA binding domain 449 518 2.0E-11 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Pfam PF00575 S1 RNA binding domain 361 434 2.2E-20 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SMART SM00316 190 260 5.0E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SMART SM00316 275 347 6.7E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SMART SM00316 449 518 1.4E-14 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SMART SM00316 103 171 2.6E-9 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SMART SM00316 362 434 1.6E-21 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SMART SM00316 19 87 5.7E-4 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Gene3D G3DSA:2.40.50.140 269 357 1.0E-29 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Gene3D G3DSA:2.40.50.140 358 443 5.0E-23 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SUPERFAMILY SSF50249 434 543 3.66E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 4 518 4.2E-223 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Gene3D G3DSA:2.40.50.140 444 526 5.7E-14 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Gene3D G3DSA:2.40.50.140 99 178 3.1E-6 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 21 39 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 84 103 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 108 124 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 39 53 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 212 233 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 290 309 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 126 143 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 155 175 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 PRINTS PR00681 Ribosomal protein S1 signature 330 348 1.2E-96 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 Gene3D G3DSA:2.40.50.140 187 268 3.1E-25 T 12-10-2018 IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SUPERFAMILY SSF50249 104 185 2.11E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_580 2f187e73751c4dacc5bc4bfe5b011d0a 552 SUPERFAMILY SSF50249 347 437 5.5E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 SUPERFAMILY SSF89360 1 97 9.22E-18 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 119 177 8.0E-19 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 97 1.1E-8 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 Gene3D G3DSA:3.30.300.130 102 188 1.5E-19 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 SUPERFAMILY SSF117916 103 185 3.27E-21 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 2 191 4.8E-83 T 12-10-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 Pfam PF01106 NifU-like domain 111 177 2.5E-17 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 191 41.087 T 12-10-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 IM45_1071 b2fc4a5f0fb17a2f308160607ebd6cf4 191 Gene3D G3DSA:2.60.300.12 1 97 1.1E-8 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 IM45_023 64d0ade76f9cd3653a4f4c240ea22979 75 Gene3D G3DSA:2.30.30.90 1 75 8.7E-22 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain IM45_023 64d0ade76f9cd3653a4f4c240ea22979 75 SMART SM00899 1 72 4.4E-4 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 IM45_023 64d0ade76f9cd3653a4f4c240ea22979 75 SUPERFAMILY SSF50037 5 70 7.1E-12 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal IM45_023 64d0ade76f9cd3653a4f4c240ea22979 75 Pfam PF04023 FeoA domain 23 64 2.7E-5 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 Pfam PF00924 Mechanosensitive ion channel 880 1078 2.1E-46 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 SUPERFAMILY SSF82689 990 1085 4.84E-13 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 484 819 2.9E-105 T 12-10-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 SUPERFAMILY SSF50182 923 988 1.14E-14 T 12-10-2018 IPR010920 LSM domain superfamily IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 Gene3D G3DSA:3.30.70.100 991 1083 7.6E-8 T 12-10-2018 IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 SUPERFAMILY SSF82861 839 921 1.83E-8 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 Gene3D G3DSA:2.30.30.60 938 987 6.9E-8 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily IM45_1291 c6e139248a12214d0cafb08b09a06112 1098 Pfam PF12795 Mechanosensitive ion channel porin domain 39 262 2.7E-46 T 12-10-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain IM45_177 0177edec0425896a94ffffb97ba368c6 221 Pfam PF00551 Formyl transferase 2 181 2.2E-59 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_177 0177edec0425896a94ffffb97ba368c6 221 Gene3D G3DSA:3.40.50.170 2 213 2.3E-77 T 12-10-2018 IM45_177 0177edec0425896a94ffffb97ba368c6 221 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 190 1.3E-72 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 IM45_177 0177edec0425896a94ffffb97ba368c6 221 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_177 0177edec0425896a94ffffb97ba368c6 221 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 29.344 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 IM45_177 0177edec0425896a94ffffb97ba368c6 221 SUPERFAMILY SSF53328 2 200 9.16E-62 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 Pfam PF09179 TilS substrate binding domain 253 320 4.8E-15 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 Gene3D G3DSA:3.40.50.620 13 238 4.7E-66 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 SUPERFAMILY SSF82829 239 323 1.57E-23 T 12-10-2018 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 SUPERFAMILY SSF52402 17 238 8.6E-57 T 12-10-2018 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 SUPERFAMILY SSF56037 337 462 4.45E-26 T 12-10-2018 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 8 315 22.825 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 Pfam PF01171 PP-loop family 25 203 2.8E-53 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 SMART SM00977 387 460 1.4E-23 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 399 433 6.2E-11 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 24 207 5.2E-49 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 Pfam PF11734 TilS substrate C-terminal domain 387 460 3.3E-25 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 IM45_242 b8423bcd9993b8ad5e9bad29a8cc0240 475 Gene3D G3DSA:1.20.59.20 239 324 6.6E-27 T 12-10-2018 IM45_829 aab2de749dfc879e541fda9d837e299f 505 Gene3D G3DSA:3.60.20.10 2 414 3.2E-155 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal IM45_829 aab2de749dfc879e541fda9d837e299f 505 SUPERFAMILY SSF56235 2 259 6.52E-72 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal IM45_829 aab2de749dfc879e541fda9d837e299f 505 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 6.9E-156 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 IM45_829 aab2de749dfc879e541fda9d837e299f 505 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 43.724 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 IM45_829 aab2de749dfc879e541fda9d837e299f 505 PIRSF PIRSF000485 1 482 2.9E-164 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 IM45_829 aab2de749dfc879e541fda9d837e299f 505 Pfam PF13522 Glutamine amidotransferase domain 65 202 4.3E-15 T 12-10-2018 IM45_829 aab2de749dfc879e541fda9d837e299f 505 SUPERFAMILY SSF53271 252 485 7.13E-66 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like IM45_829 aab2de749dfc879e541fda9d837e299f 505 Gene3D G3DSA:3.40.50.2020 279 442 3.2E-155 T 12-10-2018 IM45_829 aab2de749dfc879e541fda9d837e299f 505 Pfam PF00156 Phosphoribosyl transferase domain 287 394 3.6E-7 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 178 185 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 6 280 5.3E-106 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 SMART SM00518 6 282 6.6E-114 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 Gene3D G3DSA:3.20.20.150 4 286 1.2E-105 T 12-10-2018 IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 Pfam PF01261 Xylose isomerase-like TIM barrel 24 242 6.6E-35 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 218 234 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 SUPERFAMILY SSF51658 6 280 1.31E-90 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily IM45_880 b0a4a7354625f611faaa6aa7681d3723 291 Hamap MF_00152 Probable endonuclease 4 [nfo]. 5 282 42.133 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 566 9.6E-238 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 PIRSF PIRSF000732 1 573 1.3E-213 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 3.2E-30 T 12-10-2018 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 3.2E-30 T 12-10-2018 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 3.2E-30 T 12-10-2018 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 3.2E-30 T 12-10-2018 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 Gene3D G3DSA:3.20.20.60 234 573 2.5E-122 T 12-10-2018 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 540 2.0E-118 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 2.2E-21 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 126 6.6E-28 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 Gene3D G3DSA:1.10.274.10 21 146 6.0E-76 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 SUPERFAMILY SSF51621 250 542 1.2E-105 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 Gene3D G3DSA:3.50.30.10 4 233 6.0E-76 T 12-10-2018 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 SUPERFAMILY SSF47831 24 142 2.22E-30 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 SUPERFAMILY SSF52009 125 246 3.79E-36 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 IM45_171 c57c8b3806a9fa0c430d3cc69986d861 574 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 IM45_1017 644281d61f255232ce3a927ce377a434 412 Pfam PF00529 HlyD membrane-fusion protein of T1SS 54 360 1.9E-12 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 IM45_1017 644281d61f255232ce3a927ce377a434 412 Gene3D G3DSA:2.40.30.170 246 366 3.5E-33 T 12-10-2018 IM45_1017 644281d61f255232ce3a927ce377a434 412 SUPERFAMILY SSF111369 74 283 2.62E-13 T 12-10-2018 IM45_1017 644281d61f255232ce3a927ce377a434 412 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 75 306 5.5E-18 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain IM45_1017 644281d61f255232ce3a927ce377a434 412 Gene3D G3DSA:2.40.50.100 75 130 6.9E-9 T 12-10-2018 IM45_250 286f01b7a25c7338b8ea5247659e1150 283 Pfam PF00005 ABC transporter 70 211 1.9E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_250 286f01b7a25c7338b8ea5247659e1150 283 SMART SM00382 78 260 4.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_250 286f01b7a25c7338b8ea5247659e1150 283 Gene3D G3DSA:3.40.50.300 48 266 3.3E-47 T 12-10-2018 IM45_250 286f01b7a25c7338b8ea5247659e1150 283 SUPERFAMILY SSF52540 45 255 3.22E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 107 297 2.2E-10 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 362 429 5.5E-5 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 SUPERFAMILY SSF52922 706 887 2.75E-56 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 SUPERFAMILY SSF52518 476 702 1.14E-93 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 Gene3D G3DSA:3.40.50.970 58 473 2.6E-134 T 12-10-2018 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 Gene3D G3DSA:3.40.50.920 709 889 2.0E-67 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 7 887 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 PIRSF PIRSF000156 1 889 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 Gene3D G3DSA:3.40.50.970 474 708 9.9E-105 T 12-10-2018 IM45_1121 719f9d1c459176c9f3a299ffc6abdc82 889 SUPERFAMILY SSF52518 60 470 3.49E-143 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_195 ae9f840f2f6cc7f30a0cf201754301b4 79 Gene3D G3DSA:3.30.70.20 1 79 4.8E-16 T 12-10-2018 IM45_195 ae9f840f2f6cc7f30a0cf201754301b4 79 SUPERFAMILY SSF54862 8 73 4.19E-18 T 12-10-2018 IM45_195 ae9f840f2f6cc7f30a0cf201754301b4 79 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site IM45_195 ae9f840f2f6cc7f30a0cf201754301b4 79 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 9 73 8.4E-28 T 12-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 IM45_195 ae9f840f2f6cc7f30a0cf201754301b4 79 Pfam PF14697 4Fe-4S dicluster domain 16 70 9.0E-14 T 12-10-2018 IM45_207 e7cafee22cd2125e9b3ee7216d7aaea7 115 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 101 1.2E-44 T 12-10-2018 IPR004480 Monothiol glutaredoxin-related IM45_207 e7cafee22cd2125e9b3ee7216d7aaea7 115 Pfam PF00462 Glutaredoxin 17 81 2.2E-16 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 IM45_207 e7cafee22cd2125e9b3ee7216d7aaea7 115 PIRSF PIRSF005894 1 108 2.2E-50 T 12-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 IM45_207 e7cafee22cd2125e9b3ee7216d7aaea7 115 SUPERFAMILY SSF52833 1 102 7.68E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily IM45_207 e7cafee22cd2125e9b3ee7216d7aaea7 115 Gene3D G3DSA:3.40.30.10 2 108 8.3E-30 T 12-10-2018 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PIRSF PIRSF000532 1 320 1.6E-125 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 Gene3D G3DSA:3.40.50.460 143 252 6.6E-115 T 12-10-2018 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 Pfam PF00365 Phosphofructokinase 4 276 2.1E-103 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 240 262 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 32 45 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 2.1E-82 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 2 320 45.184 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 301 2.7E-122 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 SUPERFAMILY SSF53784 4 306 7.06E-106 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 Gene3D G3DSA:3.40.50.450 4 287 6.6E-115 T 12-10-2018 IM45_385 77418908e6bc5de5285cf020ae65ee4c 320 ProSitePatterns PS00433 Phosphofructokinase signature. 244 262 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 IM45_190 3a0571ce0e042d41e8ad5ea4f9c4fb0b 365 Pfam PF00005 ABC transporter 18 164 9.4E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_190 3a0571ce0e042d41e8ad5ea4f9c4fb0b 365 SUPERFAMILY SSF52540 3 245 3.67E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_190 3a0571ce0e042d41e8ad5ea4f9c4fb0b 365 Gene3D G3DSA:3.40.50.300 2 296 8.2E-79 T 12-10-2018 IM45_190 3a0571ce0e042d41e8ad5ea4f9c4fb0b 365 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 IM45_190 3a0571ce0e042d41e8ad5ea4f9c4fb0b 365 SUPERFAMILY SSF50331 239 342 2.55E-9 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal IM45_190 3a0571ce0e042d41e8ad5ea4f9c4fb0b 365 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 243 2.5E-121 T 12-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 IM45_190 3a0571ce0e042d41e8ad5ea4f9c4fb0b 365 SMART SM00382 27 214 7.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_647 1e09060341313726237121d96c1d1f9a 320 Gene3D G3DSA:2.170.230.10 150 259 9.3E-74 T 12-10-2018 IM45_647 1e09060341313726237121d96c1d1f9a 320 Pfam PF00717 Peptidase S24-like 81 152 4.1E-21 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C IM45_647 1e09060341313726237121d96c1d1f9a 320 Gene3D G3DSA:2.10.109.10 75 300 9.3E-74 T 12-10-2018 IM45_647 1e09060341313726237121d96c1d1f9a 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 260 279 3.9E-26 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 IM45_647 1e09060341313726237121d96c1d1f9a 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 151 3.9E-26 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 IM45_647 1e09060341313726237121d96c1d1f9a 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 91 3.9E-26 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 IM45_647 1e09060341313726237121d96c1d1f9a 320 Pfam PF10502 Signal peptidase, peptidase S26 258 297 2.8E-7 T 12-10-2018 IPR019533 Peptidase S26 IM45_647 1e09060341313726237121d96c1d1f9a 320 SUPERFAMILY SSF51306 73 319 2.98E-77 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily IM45_647 1e09060341313726237121d96c1d1f9a 320 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 61 301 1.9E-44 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 IM45_647 1e09060341313726237121d96c1d1f9a 320 ProSitePatterns PS00761 Signal peptidases I signature 3. 265 278 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 IM45_647 1e09060341313726237121d96c1d1f9a 320 ProSitePatterns PS00501 Signal peptidases I serine active site. 84 91 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 IM45_647 1e09060341313726237121d96c1d1f9a 320 ProSitePatterns PS00760 Signal peptidases I lysine active site. 141 153 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 IM45_1308 877a2a70c3164887765717f1aaf60002 370 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 365 1.1E-178 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 IM45_1308 877a2a70c3164887765717f1aaf60002 370 SUPERFAMILY SSF51713 1 363 9.16E-154 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 IM45_1308 877a2a70c3164887765717f1aaf60002 370 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 365 3.3E-168 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 IM45_1308 877a2a70c3164887765717f1aaf60002 370 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 361 4.0E-87 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 IM45_1308 877a2a70c3164887765717f1aaf60002 370 Gene3D G3DSA:3.20.20.105 1 369 1.4E-164 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 IM45_1308 877a2a70c3164887765717f1aaf60002 370 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 364 55.291 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 IM45_093 73d97334f046fb2742b806801e905b06 287 PIRSF PIRSF005052 3 287 2.0E-112 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 IM45_093 73d97334f046fb2742b806801e905b06 287 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 3 285 40.567 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 IM45_093 73d97334f046fb2742b806801e905b06 287 Pfam PF03668 P-loop ATPase protein family 3 285 1.0E-133 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 IM45_093 73d97334f046fb2742b806801e905b06 287 SUPERFAMILY SSF52540 4 154 2.83E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_430 1bdbf02dcc143d93df95122d2a8fd40d 291 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.3E-144 T 12-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 IM45_430 1bdbf02dcc143d93df95122d2a8fd40d 291 Gene3D G3DSA:3.90.550.10 1 290 4.4E-79 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases IM45_430 1bdbf02dcc143d93df95122d2a8fd40d 291 Pfam PF00483 Nucleotidyl transferase 2 238 1.3E-63 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 IM45_430 1bdbf02dcc143d93df95122d2a8fd40d 291 SUPERFAMILY SSF53448 1 287 7.66E-87 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 2.1E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 2.1E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 2.1E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 2.1E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 2.1E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 2.1E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 141 219 3.4E-13 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 Pfam PF02867 Ribonucleotide reductase, barrel domain 663 731 5.8E-7 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 658 5.8E-114 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 SUPERFAMILY SSF51998 222 738 3.05E-167 T 12-10-2018 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 1.5E-178 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 Gene3D G3DSA:3.20.70.20 209 732 3.4E-154 T 12-10-2018 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 Gene3D G3DSA:1.10.1650.20 341 394 3.4E-154 T 12-10-2018 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 Pfam PF03477 ATP cone domain 6 92 5.5E-17 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_867 9db687bb099aa8388e07bee2cf95d9ce 760 SUPERFAMILY SSF48168 10 221 1.11E-73 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_625 4c2f05384b096d34947778a4b1381d40 463 Gene3D G3DSA:1.20.1250.20 4 389 1.1E-85 T 12-10-2018 IM45_625 4c2f05384b096d34947778a4b1381d40 463 Gene3D G3DSA:3.30.70.100 390 454 1.1E-17 T 12-10-2018 IM45_625 4c2f05384b096d34947778a4b1381d40 463 Pfam PF07690 Major Facilitator Superfamily 20 354 5.1E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 IM45_625 4c2f05384b096d34947778a4b1381d40 463 SUPERFAMILY SSF103473 12 391 3.53E-54 T 12-10-2018 IPR036259 MFS transporter superfamily IM45_929 7a86f529e348ecca42c07783b5124473 188 Hamap MF_00163 Peptide deformylase [def]. 16 176 29.495 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 Pfam PF01327 Polypeptide deformylase 18 166 1.9E-47 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 19 174 5.4E-58 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 PIRSF PIRSF004749 2 186 3.4E-55 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 Gene3D G3DSA:3.90.45.10 16 183 4.4E-61 T 12-10-2018 IPR036821 Peptide deformylase superfamily IM45_929 7a86f529e348ecca42c07783b5124473 188 PRINTS PR01576 Peptide deformylase signature 47 76 8.7E-35 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 PRINTS PR01576 Peptide deformylase signature 115 133 8.7E-35 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 PRINTS PR01576 Peptide deformylase signature 103 114 8.7E-35 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 PRINTS PR01576 Peptide deformylase signature 134 163 8.7E-35 T 12-10-2018 IPR023635 Peptide deformylase IM45_929 7a86f529e348ecca42c07783b5124473 188 SUPERFAMILY SSF56420 5 175 2.49E-61 T 12-10-2018 IPR036821 Peptide deformylase superfamily IM45_621 26a953117a2e5de0065dcdad7e450dc1 328 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 44 323 1.8E-86 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 IM45_621 26a953117a2e5de0065dcdad7e450dc1 328 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 41 325 17.24 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 IM45_621 26a953117a2e5de0065dcdad7e450dc1 328 Gene3D G3DSA:1.10.357.140 52 204 3.6E-18 T 12-10-2018 IM45_621 26a953117a2e5de0065dcdad7e450dc1 328 Pfam PF01040 UbiA prenyltransferase family 58 310 6.3E-55 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 IM45_1029 12db43d0dc234f918a993d529e339bdd 477 Pfam PF01458 Uncharacterized protein family (UPF0051) 216 448 5.2E-67 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 IM45_1029 12db43d0dc234f918a993d529e339bdd 477 SUPERFAMILY SSF101960 34 474 1.57E-133 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily IM45_1029 12db43d0dc234f918a993d529e339bdd 477 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 13 468 4.5E-195 T 12-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 Pfam PF00085 Thioredoxin 5 106 1.7E-32 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 SUPERFAMILY SSF52833 4 106 1.05E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily IM45_445 43728f7d9dd9d0684de22a24489f062b 108 PRINTS PR00421 Thioredoxin family signature 72 83 4.2E-9 T 12-10-2018 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 PRINTS PR00421 Thioredoxin family signature 32 41 4.2E-9 T 12-10-2018 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 PRINTS PR00421 Thioredoxin family signature 24 32 4.2E-9 T 12-10-2018 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 1.9E-37 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 PIRSF PIRSF000077 2 108 5.8E-42 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 IM45_445 43728f7d9dd9d0684de22a24489f062b 108 Gene3D G3DSA:3.40.30.10 1 108 1.2E-35 T 12-10-2018 IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 335 59.623 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 315 3.0E-128 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 SUPERFAMILY SSF53067 1 309 1.54E-40 T 12-10-2018 IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 Gene3D G3DSA:3.30.420.40 3 315 1.7E-123 T 12-10-2018 IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 308 9.8E-116 T 12-10-2018 IPR017861 Kae1/TsaD family IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 5.6E-48 T 12-10-2018 IPR017861 Kae1/TsaD family IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 5.6E-48 T 12-10-2018 IPR017861 Kae1/TsaD family IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 5.6E-48 T 12-10-2018 IPR017861 Kae1/TsaD family IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 5.6E-48 T 12-10-2018 IPR017861 Kae1/TsaD family IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 5.6E-48 T 12-10-2018 IPR017861 Kae1/TsaD family IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 5.6E-48 T 12-10-2018 IPR017861 Kae1/TsaD family IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 Gene3D G3DSA:3.30.420.40 129 295 1.7E-123 T 12-10-2018 IM45_1353 a18533d98d08dc617bb6e48b78e9c5e6 343 Pfam PF00814 Glycoprotease family 24 309 4.4E-93 T 12-10-2018 IPR000905 Gcp-like domain IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 SUPERFAMILY SSF52540 9 287 1.54E-102 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 SMART SM00889 490 609 7.7E-75 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 PRINTS PR00315 GTP-binding elongation factor signature 85 95 2.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 PRINTS PR00315 GTP-binding elongation factor signature 137 146 2.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 PRINTS PR00315 GTP-binding elongation factor signature 101 112 2.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Gene3D G3DSA:3.30.70.240 615 685 5.2E-89 T 12-10-2018 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 SUPERFAMILY SSF54980 414 491 1.04E-24 T 12-10-2018 IPR035647 EF-G domain III/V-like IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Gene3D G3DSA:3.30.230.10 494 698 5.2E-89 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 703 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 SMART SM00838 611 698 8.8E-55 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Gene3D G3DSA:3.30.70.870 415 493 2.8E-31 T 12-10-2018 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Pfam PF00679 Elongation factor G C-terminus 611 696 5.6E-30 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Pfam PF03764 Elongation factor G, domain IV 489 609 2.3E-45 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Hamap MF_00054_B Elongation factor G [fusA]. 6 702 109.962 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Gene3D G3DSA:2.40.30.10 308 414 1.2E-42 T 12-10-2018 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Pfam PF14492 Elongation Factor G, domain II 414 488 1.3E-31 T 12-10-2018 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Pfam PF00009 Elongation factor Tu GTP binding domain 10 287 7.3E-66 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Pfam PF03144 Elongation factor Tu domain 2 334 401 2.4E-15 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 187 2.2E-30 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 SUPERFAMILY SSF54211 489 610 4.8E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 SUPERFAMILY SSF54980 611 702 4.36E-28 T 12-10-2018 IPR035647 EF-G domain III/V-like IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 SUPERFAMILY SSF50447 271 414 2.36E-34 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_1089 1e9b37e45e1cd6ff9cf605003707f2c8 705 Gene3D G3DSA:3.40.50.300 2 302 2.4E-112 T 12-10-2018 IM45_545 39e406f30affd70f1c63914de33a28fd 223 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 130 3.0E-5 T 12-10-2018 IM45_545 39e406f30affd70f1c63914de33a28fd 223 Gene3D G3DSA:3.30.930.10 2 206 4.2E-57 T 12-10-2018 IM45_545 39e406f30affd70f1c63914de33a28fd 223 PIRSF PIRSF016262 3 211 1.2E-54 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 IM45_545 39e406f30affd70f1c63914de33a28fd 223 Hamap MF_00013 Octanoyltransferase [lipB]. 7 209 35.215 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 IM45_545 39e406f30affd70f1c63914de33a28fd 223 Pfam PF03099 Biotin/lipoate A/B protein ligase family 64 161 9.6E-8 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 IM45_545 39e406f30affd70f1c63914de33a28fd 223 SUPERFAMILY SSF55681 8 209 1.49E-63 T 12-10-2018 IM45_545 39e406f30affd70f1c63914de33a28fd 223 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 29 202 2.1E-66 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 IM45_545 39e406f30affd70f1c63914de33a28fd 223 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 PIRSF PIRSF004750 10 287 4.2E-114 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 287 139.465 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 25 136 2.4E-41 T 12-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 TIGRFAM TIGR03138 QueF: queuine synthase 14 287 1.2E-117 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 SUPERFAMILY SSF55620 172 275 2.52E-10 T 12-10-2018 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 Gene3D G3DSA:3.30.1130.10 149 287 2.9E-56 T 12-10-2018 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 Pfam PF14489 QueF-like protein 201 275 1.4E-26 T 12-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 IM45_1159 5cb22a96e7d5be5f84f234d9da0ab602 287 Gene3D G3DSA:3.30.1130.10 25 144 1.4E-40 T 12-10-2018 IM45_669 7220da38b975bb113844ccd37930a49f 286 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 281 4.0E-95 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 IM45_669 7220da38b975bb113844ccd37930a49f 286 SUPERFAMILY SSF54211 3 160 9.87E-47 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_669 7220da38b975bb113844ccd37930a49f 286 Gene3D G3DSA:3.30.230.10 2 161 2.1E-51 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_669 7220da38b975bb113844ccd37930a49f 286 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 273 30.709 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 IM45_669 7220da38b975bb113844ccd37930a49f 286 SUPERFAMILY SSF55060 164 279 1.8E-34 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily IM45_669 7220da38b975bb113844ccd37930a49f 286 Pfam PF00288 GHMP kinases N terminal domain 89 146 1.8E-10 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 IM45_669 7220da38b975bb113844ccd37930a49f 286 PIRSF PIRSF010376 1 281 1.9E-78 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 IM45_669 7220da38b975bb113844ccd37930a49f 286 Gene3D G3DSA:3.30.70.890 163 281 4.4E-25 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily IM45_361 1d855615bf665098ec53f7725d3854bb 702 SUPERFAMILY SSF109604 344 498 1.78E-11 T 12-10-2018 IM45_361 1d855615bf665098ec53f7725d3854bb 702 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 695 1.2E-263 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 694 24.557 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 555 5.5E-193 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 1.8E-34 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 250 265 1.8E-34 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 322 338 1.8E-34 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 1.8E-34 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 398 417 1.8E-34 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_361 1d855615bf665098ec53f7725d3854bb 702 Pfam PF05746 DALR anticodon binding domain 588 687 1.2E-7 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 239 3.7E-36 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 387 6.0E-42 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 392 46.26 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 SUPERFAMILY SSF51735 2 150 4.4E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 6.0E-46 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 SUPERFAMILY SSF69055 302 390 8.63E-30 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 Gene3D G3DSA:3.40.50.720 1 150 4.0E-54 T 12-10-2018 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 Gene3D G3DSA:1.10.1740.10 312 396 1.7E-29 T 12-10-2018 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 SUPERFAMILY SSF55347 126 274 1.18E-62 T 12-10-2018 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 390 2.0E-171 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 IM45_1173 de48a2b27bd0c553c4ffd7dc8953570d 398 PIRSF PIRSF006205 1 397 2.8E-156 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 294 9.4E-22 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 Pfam PF00698 Acyl transferase domain 26 274 3.8E-26 T 12-10-2018 IPR014043 Acyl transferase IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 Gene3D G3DSA:3.30.70.250 109 181 1.5E-88 T 12-10-2018 IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 275 8.2E-105 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 SUPERFAMILY SSF52151 11 288 1.12E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 Gene3D G3DSA:3.40.366.10 1 269 1.5E-88 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 SUPERFAMILY SSF55048 112 181 4.97E-16 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding IM45_969 bddcbf0bc2275bfb1006c9f09c688964 299 PIRSF PIRSF000446 1 293 4.5E-115 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 105 3.0E-20 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 Gene3D G3DSA:3.10.20.400 4 97 1.7E-31 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 Gene3D G3DSA:1.10.287.1080 113 203 4.8E-25 T 12-10-2018 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 SUPERFAMILY SSF101386 115 202 2.01E-21 T 12-10-2018 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 117 202 1.8E-12 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 17.668 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 203 36.101 T 12-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 106 1.7E-28 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 SUPERFAMILY SSF141734 8 121 1.7E-44 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 IM45_892 dc50cd9318fbe38fb12db36ca90868e3 207 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 2.1E-27 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 Gene3D G3DSA:3.40.1390.20 217 359 6.1E-11 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 Pfam PF07085 DRTGG domain 229 338 7.5E-24 T 12-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 Gene3D G3DSA:3.40.50.10750 526 679 1.2E-133 T 12-10-2018 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 Pfam PF01515 Phosphate acetyl/butaryl transferase 388 703 1.1E-125 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 SUPERFAMILY SSF53659 389 706 2.51E-90 T 12-10-2018 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 Pfam PF13500 AAA domain 3 222 1.0E-42 T 12-10-2018 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 Gene3D G3DSA:3.40.50.300 5 215 4.1E-10 T 12-10-2018 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 403 703 4.8E-131 T 12-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 Gene3D G3DSA:3.40.50.10950 394 705 1.2E-133 T 12-10-2018 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 SUPERFAMILY SSF75138 226 346 1.31E-19 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 PIRSF PIRSF006107 1 711 0.0 T 12-10-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 IM45_861 cd997dd4e415587b41e9d6d41eae82c9 711 SUPERFAMILY SSF52540 1 233 8.23E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1254 831ff2ec7ba00d0ea4c6e44c7911a308 160 SUPERFAMILY SSF74982 8 138 8.89E-45 T 12-10-2018 IPR023620 Small protein B IM45_1254 831ff2ec7ba00d0ea4c6e44c7911a308 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 160 56.474 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 IM45_1254 831ff2ec7ba00d0ea4c6e44c7911a308 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 14 154 2.2E-44 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 IM45_1254 831ff2ec7ba00d0ea4c6e44c7911a308 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 138 8.0E-48 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 IM45_1254 831ff2ec7ba00d0ea4c6e44c7911a308 160 Gene3D G3DSA:2.40.280.10 6 135 2.1E-40 T 12-10-2018 IPR023620 Small protein B IM45_1254 831ff2ec7ba00d0ea4c6e44c7911a308 160 Pfam PF01668 SmpB protein 14 156 3.1E-47 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 IM45_1254 831ff2ec7ba00d0ea4c6e44c7911a308 160 ProSitePatterns PS01317 SsrA-binding protein. 32 44 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 SUPERFAMILY SSF52518 5 321 2.57E-111 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 2.9E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 Gene3D G3DSA:3.40.50.970 2 326 2.4E-123 T 12-10-2018 IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 Gene3D G3DSA:3.40.50.970 327 537 3.9E-79 T 12-10-2018 IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 Pfam PF02780 Transketolase, C-terminal domain 549 655 3.8E-15 T 12-10-2018 IPR033248 Transketolase, C-terminal domain IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 1.5E-158 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 SMART SM00861 355 525 1.7E-61 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 SUPERFAMILY SSF52922 533 664 1.31E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 Gene3D G3DSA:3.40.50.920 538 663 1.7E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 SUPERFAMILY SSF52518 338 526 2.43E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_183 aa3ef32aecbafadee7c3c7d2b646b712 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 663 0.0 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 SUPERFAMILY SSF81923 4 141 9.29E-34 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 760 4.2E-54 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 3.7E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 3.7E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 3.7E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 3.7E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 SUPERFAMILY SSF52540 546 853 5.23E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_457 ba09730e28b47ea36ef58a328c99330e 857 SUPERFAMILY SSF52540 159 545 4.96E-97 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_457 ba09730e28b47ea36ef58a328c99330e 857 SMART SM00382 597 759 5.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_457 ba09730e28b47ea36ef58a328c99330e 857 SMART SM00382 198 344 2.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Gene3D G3DSA:3.40.50.300 550 764 7.1E-88 T 12-10-2018 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Gene3D G3DSA:1.10.8.60 766 857 1.0E-24 T 12-10-2018 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Gene3D G3DSA:3.40.50.300 148 342 1.0E-72 T 12-10-2018 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 855 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 339 1.4E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Gene3D G3DSA:3.40.50.300 343 544 1.3E-66 T 12-10-2018 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 66 2.8E-7 T 12-10-2018 IPR004176 Clp, N-terminal IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 144 9.1E-6 T 12-10-2018 IPR004176 Clp, N-terminal IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 7.8E-24 T 12-10-2018 IPR019489 Clp ATPase, C-terminal IM45_457 ba09730e28b47ea36ef58a328c99330e 857 SMART SM01086 766 855 2.3E-33 T 12-10-2018 IPR019489 Clp ATPase, C-terminal IM45_457 ba09730e28b47ea36ef58a328c99330e 857 Gene3D G3DSA:1.10.1780.10 1 147 5.9E-28 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 IM45_523 f84946b578018324b450e1ae9ce3db70 151 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 114 138 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site IM45_523 f84946b578018324b450e1ae9ce3db70 151 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 32 140 3.3E-50 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 IM45_523 f84946b578018324b450e1ae9ce3db70 151 SUPERFAMILY SSF109635 9 110 9.81E-37 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily IM45_523 f84946b578018324b450e1ae9ce3db70 151 SUPERFAMILY SSF57716 111 149 6.41E-10 T 12-10-2018 IM45_523 f84946b578018324b450e1ae9ce3db70 151 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 28 150 29.911 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 IM45_523 f84946b578018324b450e1ae9ce3db70 151 Gene3D G3DSA:1.20.120.910 20 150 6.7E-35 T 12-10-2018 IM45_523 f84946b578018324b450e1ae9ce3db70 151 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 110 143 1.3E-10 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 SUPERFAMILY SSF50249 565 643 5.57E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 Gene3D G3DSA:2.40.50.140 559 645 1.5E-32 T 12-10-2018 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 Pfam PF08206 Ribonuclease B OB domain 24 80 2.7E-15 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 Gene3D G3DSA:2.40.50.140 1 82 1.3E-26 T 12-10-2018 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 Gene3D G3DSA:2.40.50.640 83 155 8.2E-23 T 12-10-2018 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 Pfam PF00773 RNB domain 190 516 1.9E-82 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 SUPERFAMILY SSF50249 10 80 3.7E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 SMART SM00955 190 518 2.0E-114 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 Pfam PF00575 S1 RNA binding domain 565 641 1.3E-7 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 Hamap MF_01036 Exoribonuclease 2 [rnb]. 1 644 43.855 T 12-10-2018 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 TIGRFAM TIGR02062 RNase_B: exoribonuclease II 1 643 2.3E-304 T 12-10-2018 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 SUPERFAMILY SSF50249 83 171 1.93E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 SUPERFAMILY SSF50249 189 557 1.77E-110 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 SMART SM00357 23 79 2.2E-9 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 ProSitePatterns PS01175 Ribonuclease II family signature. 485 509 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site IM45_680 b96ea0ceff502d6eaf115c54ac22da01 646 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 7 644 2.8E-206 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 PRINTS PR00145 Argininosuccinate lyase family signature 139 161 1.8E-7 T 12-10-2018 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 PRINTS PR00145 Argininosuccinate lyase family signature 180 200 1.8E-7 T 12-10-2018 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 PRINTS PR00145 Argininosuccinate lyase family signature 322 338 1.8E-7 T 12-10-2018 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 SUPERFAMILY SSF48557 5 460 4.12E-138 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 8 473 2.0E-244 T 12-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 Gene3D G3DSA:1.10.275.10 8 144 3.1E-54 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 Gene3D G3DSA:1.10.40.30 413 462 4.9E-27 T 12-10-2018 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 Gene3D G3DSA:1.20.200.10 145 412 8.4E-111 T 12-10-2018 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 ProSitePatterns PS00163 Fumarate lyases signature. 322 331 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 PRINTS PR00149 Fumarate lyase superfamily signature 140 158 1.9E-28 T 12-10-2018 IPR000362 Fumarate lyase family IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 1.9E-28 T 12-10-2018 IPR000362 Fumarate lyase family IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 PRINTS PR00149 Fumarate lyase superfamily signature 322 338 1.9E-28 T 12-10-2018 IPR000362 Fumarate lyase family IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 PRINTS PR00149 Fumarate lyase superfamily signature 185 203 1.9E-28 T 12-10-2018 IPR000362 Fumarate lyase family IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 Pfam PF10415 Fumarase C C-terminus 413 465 2.4E-15 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 IM45_1299 1f11d47bb9cefdd7d69ac51456d68f50 474 Pfam PF00206 Lyase 15 347 1.3E-100 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 Gene3D G3DSA:3.30.300.10 5 233 5.9E-177 T 12-10-2018 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 379 4.0E-193 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 381 58.024 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 SUPERFAMILY SSF55973 233 379 2.43E-69 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 SUPERFAMILY SSF55973 3 109 1.1E-45 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 3.4E-44 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 370 4.5E-69 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 Gene3D G3DSA:3.30.300.10 103 372 5.9E-177 T 12-10-2018 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 Gene3D G3DSA:3.30.300.10 11 270 5.9E-177 T 12-10-2018 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 5.8E-42 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 PIRSF PIRSF000497 1 381 1.0E-172 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_033 08554cbd45d0b7d2be7d7ade339398d3 382 SUPERFAMILY SSF55973 113 232 2.12E-50 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 IM45_1325 f1af49264d3afbb614d089a8daa4501f 175 Pfam PF04608 Phosphatidylglycerophosphatase A 19 160 2.5E-47 T 12-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 IM45_1325 f1af49264d3afbb614d089a8daa4501f 175 PIRSF PIRSF006162 8 167 2.4E-49 T 12-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 IM45_1325 f1af49264d3afbb614d089a8daa4501f 175 SUPERFAMILY SSF101307 14 161 7.06E-42 T 12-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 IM45_974 e55e92185ec454676460a68ad1a0e5d8 338 Pfam PF02504 Fatty acid synthesis protein 5 317 1.0E-102 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 IM45_974 e55e92185ec454676460a68ad1a0e5d8 338 Gene3D G3DSA:3.40.718.10 3 336 6.8E-111 T 12-10-2018 IM45_974 e55e92185ec454676460a68ad1a0e5d8 338 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 331 120.968 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 IM45_974 e55e92185ec454676460a68ad1a0e5d8 338 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 325 2.7E-110 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 IM45_974 e55e92185ec454676460a68ad1a0e5d8 338 PIRSF PIRSF002465 2 331 2.8E-112 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 IM45_974 e55e92185ec454676460a68ad1a0e5d8 338 SUPERFAMILY SSF53659 4 325 2.8E-92 T 12-10-2018 IM45_607 baf600900d9f8723eeb966f81469cf92 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 417 53.264 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 IM45_607 baf600900d9f8723eeb966f81469cf92 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 312 2.0E-48 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 IM45_607 baf600900d9f8723eeb966f81469cf92 426 SMART SM00994 12 51 1.0E-24 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 IM45_607 baf600900d9f8723eeb966f81469cf92 426 Gene3D G3DSA:1.10.8.60 318 426 5.1E-42 T 12-10-2018 IM45_607 baf600900d9f8723eeb966f81469cf92 426 Gene3D G3DSA:3.30.50.30 2 52 2.4E-27 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily IM45_607 baf600900d9f8723eeb966f81469cf92 426 SUPERFAMILY SSF52540 62 404 2.63E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_607 baf600900d9f8723eeb966f81469cf92 426 SMART SM00382 113 335 6.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_607 baf600900d9f8723eeb966f81469cf92 426 SMART SM01086 319 414 8.5E-34 T 12-10-2018 IPR019489 Clp ATPase, C-terminal IM45_607 baf600900d9f8723eeb966f81469cf92 426 SUPERFAMILY SSF57716 13 48 5.84E-12 T 12-10-2018 IM45_607 baf600900d9f8723eeb966f81469cf92 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 414 2.9E-212 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 IM45_607 baf600900d9f8723eeb966f81469cf92 426 Pfam PF06689 ClpX C4-type zinc finger 13 50 1.2E-20 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 IM45_607 baf600900d9f8723eeb966f81469cf92 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 397 6.8E-17 T 12-10-2018 IPR019489 Clp ATPase, C-terminal IM45_607 baf600900d9f8723eeb966f81469cf92 426 Gene3D G3DSA:3.40.50.300 58 317 2.1E-107 T 12-10-2018 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 Pfam PF13932 GidA associated domain 403 616 4.2E-72 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 SMART SM01228 546 617 3.2E-37 T 12-10-2018 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 Gene3D G3DSA:1.10.10.1800 459 550 1.7E-27 T 12-10-2018 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 40.715 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 Gene3D G3DSA:3.50.50.60 2 237 2.3E-86 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 Gene3D G3DSA:3.50.50.60 293 458 3.9E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 Gene3D G3DSA:1.10.150.570 570 622 1.8E-20 T 12-10-2018 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 Pfam PF01134 Glucose inhibited division protein A 8 399 4.3E-163 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 SUPERFAMILY SSF51905 6 261 6.64E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_343 58f80ca9afa3c40ac0d63d1ac7b14bae 630 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 8.8E-276 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 IM45_079 7bdfbe5af5c9149742fe1a1eeb1741eb 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 3.1E-62 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_079 7bdfbe5af5c9149742fe1a1eeb1741eb 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 27.11 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 IM45_079 7bdfbe5af5c9149742fe1a1eeb1741eb 142 Pfam PF00572 Ribosomal protein L13 15 138 3.2E-54 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 IM45_079 7bdfbe5af5c9149742fe1a1eeb1741eb 142 SUPERFAMILY SSF52161 1 140 1.57E-56 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_079 7bdfbe5af5c9149742fe1a1eeb1741eb 142 PIRSF PIRSF002181 1 142 2.1E-47 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 IM45_079 7bdfbe5af5c9149742fe1a1eeb1741eb 142 Gene3D G3DSA:3.90.1180.10 1 142 1.9E-60 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_079 7bdfbe5af5c9149742fe1a1eeb1741eb 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 IM45_990 cc0f44964b4e4544e01e65792234fb3e 223 SUPERFAMILY SSF63848 116 220 1.7E-29 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 IM45_990 cc0f44964b4e4544e01e65792234fb3e 223 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 119 213 1.3E-28 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 IM45_990 cc0f44964b4e4544e01e65792234fb3e 223 Gene3D G3DSA:3.30.750.120 1 113 3.1E-34 T 12-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily IM45_990 cc0f44964b4e4544e01e65792234fb3e 223 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 1 103 5.1E-30 T 12-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 IM45_990 cc0f44964b4e4544e01e65792234fb3e 223 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 6 221 6.6E-65 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 IM45_990 cc0f44964b4e4544e01e65792234fb3e 223 Gene3D G3DSA:2.160.20.70 114 222 1.8E-27 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 IM45_990 cc0f44964b4e4544e01e65792234fb3e 223 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 5 222 26.062 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 IM45_159 091d1957ca142b57a87337392ee36f45 408 SUPERFAMILY SSF51905 22 395 1.37E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_159 091d1957ca142b57a87337392ee36f45 408 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 22 407 1.7E-116 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 IM45_159 091d1957ca142b57a87337392ee36f45 408 Gene3D G3DSA:3.30.9.50 97 286 3.6E-97 T 12-10-2018 IM45_159 091d1957ca142b57a87337392ee36f45 408 Pfam PF01494 FAD binding domain 21 356 1.2E-28 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 IM45_159 091d1957ca142b57a87337392ee36f45 408 Gene3D G3DSA:3.50.50.60 22 355 3.6E-97 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_159 091d1957ca142b57a87337392ee36f45 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 1.2E-20 T 12-10-2018 IM45_159 091d1957ca142b57a87337392ee36f45 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 22 44 1.2E-20 T 12-10-2018 IM45_159 091d1957ca142b57a87337392ee36f45 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 172 187 1.2E-20 T 12-10-2018 IM45_159 091d1957ca142b57a87337392ee36f45 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 1.2E-20 T 12-10-2018 IM45_443 3658d43adf538283aed9565ebc13709e 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 7.7E-16 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 IM45_443 3658d43adf538283aed9565ebc13709e 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.6E-22 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_443 3658d43adf538283aed9565ebc13709e 419 Gene3D G3DSA:1.10.720.10 1 47 3.3E-23 T 12-10-2018 IM45_443 3658d43adf538283aed9565ebc13709e 419 Gene3D G3DSA:2.40.50.140 48 117 2.8E-35 T 12-10-2018 IM45_443 3658d43adf538283aed9565ebc13709e 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 4.7E-32 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 IM45_443 3658d43adf538283aed9565ebc13709e 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 6.0E-222 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 IM45_443 3658d43adf538283aed9565ebc13709e 419 SUPERFAMILY SSF50249 48 125 1.88E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_443 3658d43adf538283aed9565ebc13709e 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 251.072 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 IM45_443 3658d43adf538283aed9565ebc13709e 419 SUPERFAMILY SSF68912 1 46 2.47E-11 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily IM45_443 3658d43adf538283aed9565ebc13709e 419 SMART SM00959 5 47 9.4E-17 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 IM45_443 3658d43adf538283aed9565ebc13709e 419 SMART SM00382 170 355 9.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_443 3658d43adf538283aed9565ebc13709e 419 Gene3D G3DSA:3.40.50.300 130 417 4.6E-134 T 12-10-2018 IM45_443 3658d43adf538283aed9565ebc13709e 419 SMART SM00357 52 118 3.3E-18 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 IM45_443 3658d43adf538283aed9565ebc13709e 419 SUPERFAMILY SSF52540 90 371 1.71E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_813 65e2c7a9178fe62da8deb4251d718783 358 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_813 65e2c7a9178fe62da8deb4251d718783 358 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 7.4E-133 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_813 65e2c7a9178fe62da8deb4251d718783 358 PIRSF PIRSF001456 3 356 7.6E-138 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_813 65e2c7a9178fe62da8deb4251d718783 358 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_813 65e2c7a9178fe62da8deb4251d718783 358 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 36.328 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_813 65e2c7a9178fe62da8deb4251d718783 358 Gene3D G3DSA:3.60.150.10 1 358 7.3E-152 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_813 65e2c7a9178fe62da8deb4251d718783 358 SUPERFAMILY SSF103263 4 352 6.02E-141 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_813 65e2c7a9178fe62da8deb4251d718783 358 Pfam PF01264 Chorismate synthase 10 345 1.6E-136 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 Pfam PF00117 Glutamine amidotransferase class-I 19 194 5.1E-19 T 12-10-2018 IPR017926 Glutamine amidotransferase IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 174 187 9.5E-5 T 12-10-2018 IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 72 83 9.5E-5 T 12-10-2018 IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 196 1.4E-66 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 196 31.816 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 Gene3D G3DSA:3.40.50.880 1 196 2.9E-65 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 PIRSF PIRSF000495 1 196 5.8E-62 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 IM45_898 f1a060e90d561c7271085b2e072f7f1b 196 SUPERFAMILY SSF52317 3 195 5.24E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_1221 c8a9e390587fafde1e7feb89c6ca0280 86 Gene3D G3DSA:1.20.58.110 1 86 5.5E-30 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1221 c8a9e390587fafde1e7feb89c6ca0280 86 Pfam PF01649 Ribosomal protein S20 2 84 2.7E-27 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1221 c8a9e390587fafde1e7feb89c6ca0280 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 3.0E-28 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1221 c8a9e390587fafde1e7feb89c6ca0280 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 4.7E-31 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1221 c8a9e390587fafde1e7feb89c6ca0280 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.083 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1221 c8a9e390587fafde1e7feb89c6ca0280 86 SUPERFAMILY SSF46992 3 86 5.75E-31 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Gene3D G3DSA:3.30.230.10 217 328 5.0E-36 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 SUPERFAMILY SSF118116 388 568 1.2E-34 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 SUPERFAMILY SSF54211 191 329 3.79E-29 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Gene3D G3DSA:2.30.42.20 390 567 1.3E-58 T 12-10-2018 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Gene3D G3DSA:3.30.1370.100 434 522 1.3E-58 T 12-10-2018 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Pfam PF08676 MutL C terminal dimerisation domain 390 520 7.4E-21 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 328 1.9E-33 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 568 24.079 T 12-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 130 3.4E-16 T 12-10-2018 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 SMART SM01340 212 329 3.4E-44 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 SMART SM00853 393 525 4.4E-10 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 Gene3D G3DSA:3.30.565.10 1 216 2.0E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 SUPERFAMILY SSF55874 1 200 2.23E-56 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily IM45_1281 d92654ea40ad5948c0c627ddb5af1d6e 571 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 309 5.9E-98 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 IM45_994 883d191eccaa64c6321b50df9fb8adc2 93 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 2.3E-29 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 IM45_994 883d191eccaa64c6321b50df9fb8adc2 93 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 3.4E-19 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 IM45_994 883d191eccaa64c6321b50df9fb8adc2 93 Gene3D G3DSA:3.30.1070.10 1 83 1.8E-22 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 IM45_994 883d191eccaa64c6321b50df9fb8adc2 93 SUPERFAMILY SSF55229 34 84 4.18E-12 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 IM45_994 883d191eccaa64c6321b50df9fb8adc2 93 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 17.676 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 Gene3D G3DSA:3.30.70.1660 111 341 3.1E-91 T 12-10-2018 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 SUPERFAMILY SSF75620 12 353 7.72E-128 T 12-10-2018 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 Pfam PF03462 PCRF domain 12 203 3.2E-71 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 Pfam PF00472 RF-1 domain 216 321 7.3E-38 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 Gene3D G3DSA:3.30.160.20 210 297 3.1E-91 T 12-10-2018 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 SMART SM00937 67 178 7.1E-62 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 38.662 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 IM45_665 9ed93aecdfda989ebef923874119fcc6 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 358 7.9E-158 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 IM45_150 5afd3800db232f22e13943b615d19494 246 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 241 5.5E-33 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_150 5afd3800db232f22e13943b615d19494 246 Gene3D G3DSA:3.40.50.10090 32 165 6.1E-61 T 12-10-2018 IM45_150 5afd3800db232f22e13943b615d19494 246 Gene3D G3DSA:3.40.50.10090 4 245 6.1E-61 T 12-10-2018 IM45_150 5afd3800db232f22e13943b615d19494 246 SUPERFAMILY SSF69618 1 245 3.4E-50 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_509 c6ce228a9c2c7b377289146d79cf13d8 223 Pfam PF13394 4Fe-4S single cluster domain 24 128 3.0E-11 T 12-10-2018 IM45_509 c6ce228a9c2c7b377289146d79cf13d8 223 Gene3D G3DSA:3.20.20.70 2 223 9.2E-49 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_509 c6ce228a9c2c7b377289146d79cf13d8 223 PIRSF PIRSF000370 1 223 4.6E-65 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 IM45_509 c6ce228a9c2c7b377289146d79cf13d8 223 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 9 222 1.1E-105 T 12-10-2018 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 IM45_509 c6ce228a9c2c7b377289146d79cf13d8 223 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 223 32.765 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 IM45_509 c6ce228a9c2c7b377289146d79cf13d8 223 SUPERFAMILY SSF102114 23 109 2.35E-5 T 12-10-2018 IM45_509 c6ce228a9c2c7b377289146d79cf13d8 223 Pfam PF04055 Radical SAM superfamily 27 182 9.7E-8 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 IM45_337 ea2112a7757e1db41f2d285c2b2ca5cf 159 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 11.204 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 IM45_337 ea2112a7757e1db41f2d285c2b2ca5cf 159 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 1.1E-25 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 IM45_337 ea2112a7757e1db41f2d285c2b2ca5cf 159 Gene3D G3DSA:1.20.5.620 62 122 5.3E-11 T 12-10-2018 IM45_337 ea2112a7757e1db41f2d285c2b2ca5cf 159 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 2.2E-40 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 IM45_337 ea2112a7757e1db41f2d285c2b2ca5cf 159 SUPERFAMILY SSF81573 63 121 4.71E-10 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily IM45_1035 ea6ca54e6ee82cb37d6a367d09bc06bf 327 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 19 84 4.7E-18 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 IM45_1035 ea6ca54e6ee82cb37d6a367d09bc06bf 327 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 327 8.1E-106 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 IM45_1035 ea6ca54e6ee82cb37d6a367d09bc06bf 327 Gene3D G3DSA:3.30.930.10 7 327 8.6E-117 T 12-10-2018 IM45_1035 ea6ca54e6ee82cb37d6a367d09bc06bf 327 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 326 46.778 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 IM45_1035 ea6ca54e6ee82cb37d6a367d09bc06bf 327 Pfam PF01409 tRNA synthetases class II core domain (F) 92 326 1.7E-98 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 IM45_1035 ea6ca54e6ee82cb37d6a367d09bc06bf 327 SUPERFAMILY SSF46589 14 99 1.94E-17 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 IM45_1035 ea6ca54e6ee82cb37d6a367d09bc06bf 327 SUPERFAMILY SSF55681 92 327 6.52E-79 T 12-10-2018 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 SUPERFAMILY SSF50156 96 286 8.41E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 Pfam PF02163 Peptidase family M50 11 445 1.1E-72 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 Gene3D G3DSA:2.30.42.10 131 225 7.2E-19 T 12-10-2018 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 Gene3D G3DSA:2.30.42.10 228 316 1.1E-17 T 12-10-2018 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 8 457 2.2E-123 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 231 282 1.4E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 SUPERFAMILY SSF50156 93 186 1.27E-5 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 IM45_1179 6c039949c0edee7b8faf526f8add27f4 457 SMART SM00228 217 286 7.2E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 Pfam PF13432 Tetratricopeptide repeat 115 168 7.2E-5 T 12-10-2018 IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 102 216 4.5E-38 T 12-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 Pfam PF16331 TolA binding protein trimerisation 38 90 2.4E-12 T 12-10-2018 IPR032519 YbgF, trimerisation domain GO:0070206 IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 SUPERFAMILY SSF48452 98 214 8.04E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 2 221 17.088 T 12-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 Gene3D G3DSA:1.20.5.110 33 104 1.8E-18 T 12-10-2018 IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 Gene3D G3DSA:1.25.40.10 105 221 1.3E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 IM45_238 0b10926cb6e41dab1b7e66124c3aab3c 221 Pfam PF13174 Tetratricopeptide repeat 176 208 1.6E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 IM45_280 3f26cf92b8ff031c4dc037c6654e9892 147 SMART SM01001 1 137 3.2E-77 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 IM45_280 3f26cf92b8ff031c4dc037c6654e9892 147 SUPERFAMILY SSF52255 1 142 5.23E-55 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 IM45_280 3f26cf92b8ff031c4dc037c6654e9892 147 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 141 24.992 T 12-10-2018 IPR033747 Class I PurE IM45_280 3f26cf92b8ff031c4dc037c6654e9892 147 Pfam PF00731 AIR carboxylase 1 135 6.5E-52 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 IM45_280 3f26cf92b8ff031c4dc037c6654e9892 147 Gene3D G3DSA:3.40.50.7700 1 147 4.0E-60 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 IM45_280 3f26cf92b8ff031c4dc037c6654e9892 147 PIRSF PIRSF001338 1 145 1.2E-56 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 IM45_280 3f26cf92b8ff031c4dc037c6654e9892 147 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 141 1.0E-52 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 IM45_998 6823061cb9ad23a1f524b252232cf8fa 297 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 26 295 1.8E-107 T 12-10-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 IM45_998 6823061cb9ad23a1f524b252232cf8fa 297 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 26 295 5.2E-134 T 12-10-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 IM45_525 51099418dc42035fd5c71fb1726c13b1 171 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 8 137 2.2E-34 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 IM45_525 51099418dc42035fd5c71fb1726c13b1 171 SUPERFAMILY SSF55083 4 159 1.1E-50 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 IM45_525 51099418dc42035fd5c71fb1726c13b1 171 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 8 137 3.4E-41 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 IM45_525 51099418dc42035fd5c71fb1726c13b1 171 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 92 103 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 IM45_525 51099418dc42035fd5c71fb1726c13b1 171 Gene3D G3DSA:3.30.70.560 4 162 4.6E-52 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 IM45_954 1a63adda88c69389a84b33e701da349d 158 Gene3D G3DSA:3.40.50.10610 45 157 2.4E-28 T 12-10-2018 IM45_954 1a63adda88c69389a84b33e701da349d 158 Pfam PF13036 Peptidoglycan-synthase activator LpoB 45 135 2.3E-11 T 12-10-2018 IPR014094 Penicillin-binding protein activator LpoB IM45_403 bda96597fdde3beca352a0ecb8150882 269 SUPERFAMILY SSF81624 2 138 1.44E-40 T 12-10-2018 IPR035937 MutM-like, N-terminal IM45_403 bda96597fdde3beca352a0ecb8150882 269 Gene3D G3DSA:3.20.190.10 2 128 1.8E-40 T 12-10-2018 IPR035937 MutM-like, N-terminal IM45_403 bda96597fdde3beca352a0ecb8150882 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 244 268 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 IM45_403 bda96597fdde3beca352a0ecb8150882 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 5.4E-91 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 IM45_403 bda96597fdde3beca352a0ecb8150882 269 Gene3D G3DSA:1.10.8.50 139 269 1.3E-40 T 12-10-2018 IM45_403 bda96597fdde3beca352a0ecb8150882 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 129 218 3.7E-23 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 IM45_403 bda96597fdde3beca352a0ecb8150882 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 6.5E-31 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 IM45_403 bda96597fdde3beca352a0ecb8150882 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 269 1.3E-4 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 IM45_403 bda96597fdde3beca352a0ecb8150882 269 SUPERFAMILY SSF57716 217 268 4.28E-14 T 12-10-2018 IM45_403 bda96597fdde3beca352a0ecb8150882 269 SMART SM00898 2 115 1.6E-49 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 IM45_403 bda96597fdde3beca352a0ecb8150882 269 SMART SM01232 129 221 2.9E-38 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 IM45_403 bda96597fdde3beca352a0ecb8150882 269 SUPERFAMILY SSF46946 130 221 1.91E-26 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 IM45_403 bda96597fdde3beca352a0ecb8150882 269 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 269 40.494 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 SUPERFAMILY SSF53738 156 255 2.24E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 SUPERFAMILY SSF53738 258 365 1.77E-31 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 134 1.6E-43 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 444 46.946 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 364 5.2E-33 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 442 6.8E-194 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 1.7E-19 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 2.0E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 2.0E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 2.0E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 SUPERFAMILY SSF55957 357 444 1.11E-20 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Gene3D G3DSA:3.40.120.10 174 362 5.5E-65 T 12-10-2018 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Gene3D G3DSA:3.40.120.10 257 339 5.5E-65 T 12-10-2018 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Gene3D G3DSA:3.40.120.10 3 154 3.4E-46 T 12-10-2018 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 SUPERFAMILY SSF53738 3 181 2.24E-47 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Gene3D G3DSA:3.30.310.50 370 445 1.5E-23 T 12-10-2018 IM45_1393 6d587101103394b6b8d7e47da4af4077 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 3.6E-13 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_627 3c33ffbfd9ef2da2dfa3bd63ada96f86 294 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 142 3.9E-21 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain IM45_627 3c33ffbfd9ef2da2dfa3bd63ada96f86 294 SUPERFAMILY SSF48179 168 289 6.12E-35 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 IM45_627 3c33ffbfd9ef2da2dfa3bd63ada96f86 294 Gene3D G3DSA:1.10.1040.10 168 290 3.8E-40 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 IM45_627 3c33ffbfd9ef2da2dfa3bd63ada96f86 294 SUPERFAMILY SSF51735 2 167 1.71E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_627 3c33ffbfd9ef2da2dfa3bd63ada96f86 294 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 168 289 1.9E-31 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain IM45_627 3c33ffbfd9ef2da2dfa3bd63ada96f86 294 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 291 7.9E-69 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 IM45_627 3c33ffbfd9ef2da2dfa3bd63ada96f86 294 Gene3D G3DSA:3.40.50.720 1 167 5.9E-47 T 12-10-2018 IM45_517 397689a8f8374a66a9e2a22172dccd8c 235 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 228 6.1E-87 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 IM45_517 397689a8f8374a66a9e2a22172dccd8c 235 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 229 42.775 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 IM45_517 397689a8f8374a66a9e2a22172dccd8c 235 Pfam PF01048 Phosphorylase superfamily 3 226 9.5E-48 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 IM45_517 397689a8f8374a66a9e2a22172dccd8c 235 SUPERFAMILY SSF53167 1 229 3.14E-67 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 IM45_517 397689a8f8374a66a9e2a22172dccd8c 235 Gene3D G3DSA:3.40.50.1580 1 233 4.3E-64 T 12-10-2018 IM45_731 38562d1ab645821f0d60b442110f5ea6 191 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 14 191 1.1E-61 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 IM45_731 38562d1ab645821f0d60b442110f5ea6 191 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 1 190 25.217 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 IM45_731 38562d1ab645821f0d60b442110f5ea6 191 SUPERFAMILY SSF89392 14 191 5.89E-41 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX IM45_731 38562d1ab645821f0d60b442110f5ea6 191 Gene3D G3DSA:2.50.20.10 10 191 2.4E-41 T 12-10-2018 IM45_731 38562d1ab645821f0d60b442110f5ea6 191 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 22 180 4.1E-38 T 12-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 Gene3D G3DSA:3.40.50.880 2 194 5.2E-59 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 6.1E-15 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 6.1E-15 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 76 87 6.1E-15 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 SUPERFAMILY SSF52317 3 193 1.61E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 Pfam PF00117 Glutamine amidotransferase class-I 6 191 3.6E-50 T 12-10-2018 IPR017926 Glutamine amidotransferase IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 76 92 1.5E-6 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 1.5E-6 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 192 7.6E-82 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00097 Anthranilate synthase component II signature 76 87 1.3E-34 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00097 Anthranilate synthase component II signature 121 133 1.3E-34 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00097 Anthranilate synthase component II signature 170 183 1.3E-34 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00097 Anthranilate synthase component II signature 4 18 1.3E-34 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00097 Anthranilate synthase component II signature 101 109 1.3E-34 T 12-10-2018 IM45_1213 f26ad0a02b4a1f72820301bb0453595b 195 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.3E-34 T 12-10-2018 IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 PIRSF PIRSF000525 1 361 1.2E-146 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 360 2.2E-152 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 SUPERFAMILY SSF53383 1 358 8.31E-112 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 Gene3D G3DSA:3.90.1150.10 259 361 5.0E-38 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 188 207 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 360 49.983 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 Pfam PF00266 Aminotransferase class-V 4 349 6.8E-61 T 12-10-2018 IPR000192 Aminotransferase class V domain IM45_574 630ed2fb117ccfdfc601fafca83947f3 361 Gene3D G3DSA:3.40.640.10 16 258 2.9E-90 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 Gene3D G3DSA:1.10.260.30 328 450 3.5E-39 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 SMART SM00962 100 296 3.2E-104 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 1.9E-70 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 SMART SM00382 99 301 4.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 SMART SM00963 1 86 2.2E-31 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 SUPERFAMILY SSF52540 42 351 5.98E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 447 32.391 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 3.4E-163 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 SUPERFAMILY SSF47446 298 432 1.57E-40 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 Gene3D G3DSA:3.40.50.300 90 285 1.3E-114 T 12-10-2018 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 Pfam PF02978 Signal peptide binding domain 329 428 2.2E-29 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.9E-18 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_467 dc11aa69c00d631fe2cccaf8d3dbcfe0 454 Gene3D G3DSA:1.20.120.140 4 305 1.3E-114 T 12-10-2018 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 6.1E-74 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 2.5E-118 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 Gene3D G3DSA:3.50.50.60 118 244 4.9E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 SUPERFAMILY SSF51905 8 315 9.07E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 302 2.0E-47 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 2.6E-40 T 12-10-2018 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.6E-40 T 12-10-2018 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 2.6E-40 T 12-10-2018 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 2.6E-40 T 12-10-2018 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.6E-40 T 12-10-2018 IM45_735 ce4c36e9dac4f73272438b4a24473f74 318 Gene3D G3DSA:3.50.50.60 10 312 4.9E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 Gene3D G3DSA:3.40.50.10490 9 218 1.8E-93 T 12-10-2018 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 40.838 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.7E-36 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.7E-36 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.7E-36 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.7E-36 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.7E-36 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.7E-36 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 SUPERFAMILY SSF52313 6 226 6.8E-94 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 225 1.8E-105 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 Pfam PF00318 Ribosomal protein S2 9 224 3.5E-93 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1165 175872dfcae45c8df6e9f3a52bbe66a3 240 Gene3D G3DSA:1.10.287.610 103 150 1.8E-93 T 12-10-2018 IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 Pfam PF00588 SpoU rRNA Methylase family 98 240 2.3E-38 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 2 247 41.781 T 12-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 1 246 4.3E-81 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 4 78 2.3E-20 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 SUPERFAMILY SSF75217 89 246 7.19E-48 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 Gene3D G3DSA:3.40.1280.10 78 247 1.0E-57 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 SUPERFAMILY SSF55315 2 75 3.88E-19 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 Gene3D G3DSA:3.30.1330.30 1 75 6.0E-28 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like IM45_1267 bcec4a0bc0856d2e3bf65f71642c7e56 248 SMART SM00967 4 80 9.8E-21 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 157 1.3E-26 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 Gene3D G3DSA:3.10.50.30 76 158 6.4E-30 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 2.0E-57 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 PIRSF PIRSF006092 1 158 4.6E-53 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.226 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 Gene3D G3DSA:1.10.287.180 1 75 6.0E-32 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 SUPERFAMILY SSF46557 3 76 2.09E-28 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 SUPERFAMILY SSF54534 82 157 8.24E-22 T 12-10-2018 IM45_1399 f4db06162d059458ae4d116c30dc3d3f 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 1.6E-30 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 SUPERFAMILY SSF51690 130 299 2.94E-54 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 Gene3D G3DSA:3.20.20.70 139 289 2.3E-109 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 PIRSF PIRSF006250 17 300 6.7E-100 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 Gene3D G3DSA:3.90.1170.20 21 298 2.3E-109 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 SUPERFAMILY SSF54675 15 129 1.1E-29 T 12-10-2018 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 28 298 2.3E-95 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 130 298 2.6E-57 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 IM45_1123 820d9f58e43b69bfd1fb44285ae6b89f 300 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 43 128 5.1E-25 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 IM45_129 0bcd07c20b43ae49305e382d01a6d8a7 683 SUPERFAMILY SSF55486 1 677 4.79E-193 T 12-10-2018 IM45_129 0bcd07c20b43ae49305e382d01a6d8a7 683 Pfam PF01432 Peptidase family M3 222 677 8.5E-162 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 IM45_129 0bcd07c20b43ae49305e382d01a6d8a7 683 Gene3D G3DSA:1.10.1370.10 140 610 1.4E-251 T 12-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 IM45_129 0bcd07c20b43ae49305e382d01a6d8a7 683 Gene3D G3DSA:1.10.1370.40 13 675 1.4E-251 T 12-10-2018 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 Gene3D G3DSA:3.30.2350.10 101 324 4.9E-79 T 12-10-2018 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 27 322 4.4E-89 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 SMART SM00363 29 93 1.3E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 Pfam PF00849 RNA pseudouridylate synthase 109 257 2.1E-27 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 Gene3D G3DSA:3.10.290.10 17 84 2.0E-16 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 SUPERFAMILY SSF55120 103 321 2.88E-61 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 148 162 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 SUPERFAMILY SSF55174 28 79 9.94E-9 T 12-10-2018 IM45_978 2ce16a6019ea2c496eedc60dd1283517 329 Pfam PF01479 S4 domain 29 75 5.9E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 1.9E-25 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.9E-25 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.9E-25 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.9E-25 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 SMART SM00347 22 123 3.4E-27 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 Hamap MF_01819 Transcriptional regulator SlyA [slyA]. 1 143 37.858 T 12-10-2018 IPR023071 Transcriptional regulator, SlyA IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 SUPERFAMILY SSF46785 4 140 2.16E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 Pfam PF01047 MarR family 29 87 2.8E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_201 529e93bbcc4c16b1e99d67af7a5cc01e 144 Gene3D G3DSA:1.10.10.10 1 143 5.0E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_1079 d51615ade7d117f1c17dedafb9440962 140 SUPERFAMILY SSF75169 15 140 2.75E-33 T 12-10-2018 IPR027396 DsrEFH-like IM45_1079 d51615ade7d117f1c17dedafb9440962 140 Gene3D G3DSA:3.40.1260.10 5 140 5.4E-50 T 12-10-2018 IPR027396 DsrEFH-like IM45_1079 d51615ade7d117f1c17dedafb9440962 140 Pfam PF02635 DsrE/DsrF-like family 15 140 7.9E-24 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein IM45_1079 d51615ade7d117f1c17dedafb9440962 140 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 15 140 1.5E-47 T 12-10-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 IM45_1079 d51615ade7d117f1c17dedafb9440962 140 Hamap MF_00390 Sulfurtransferase TusD [tusD]. 13 140 35.265 T 12-10-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:3.90.1100.10 439 622 8.7E-71 T 12-10-2018 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Pfam PF10385 RNA polymerase beta subunit external 1 domain 588 653 1.3E-25 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 SUPERFAMILY SSF64484 11 1339 0.0 T 12-10-2018 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1062 1074 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Pfam PF04561 RNA polymerase Rpb2, domain 2 336 451 2.1E-15 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Pfam PF04561 RNA polymerase Rpb2, domain 2 161 223 5.8E-8 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:3.90.1800.10 1251 1304 8.2E-11 T 12-10-2018 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Pfam PF04565 RNA polymerase Rpb2, domain 3 510 577 1.5E-30 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Pfam PF00562 RNA polymerase Rpb2, domain 6 714 1263 1.7E-157 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:2.40.270.10 999 1241 6.4E-91 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:2.40.50.100 711 785 4.1E-31 T 12-10-2018 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1341 12.254 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Pfam PF04560 RNA polymerase Rpb2, domain 7 1265 1339 2.7E-27 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:3.90.1100.10 639 710 1.1E-20 T 12-10-2018 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:3.90.1100.10 18 171 7.8E-56 T 12-10-2018 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Pfam PF04563 RNA polymerase beta subunit 26 497 6.6E-52 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:2.40.50.150 830 952 1.9E-43 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:3.90.1110.10 297 438 9.0E-37 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 Gene3D G3DSA:2.40.270.10 787 829 2.5E-6 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1105 3f71133f7ec5e3c74407f688cbb8c55c 1341 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1338 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_986 c9185c39de099a64c38768e2f6727007 332 Gene3D G3DSA:3.40.50.720 4 326 9.9E-151 T 12-10-2018 IM45_986 c9185c39de099a64c38768e2f6727007 332 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 1.1E-130 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 SUPERFAMILY SSF55347 149 312 5.06E-77 T 12-10-2018 IM45_986 c9185c39de099a64c38768e2f6727007 332 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 SUPERFAMILY SSF51735 3 166 5.73E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_986 c9185c39de099a64c38768e2f6727007 332 SMART SM00846 3 150 2.3E-87 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 Gene3D G3DSA:3.30.360.10 149 314 9.9E-151 T 12-10-2018 IM45_986 c9185c39de099a64c38768e2f6727007 332 PIRSF PIRSF000149 1 332 3.3E-128 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 4.4E-45 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 4.4E-45 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.4E-45 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 4.4E-45 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 4.4E-45 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 1.6E-67 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_986 c9185c39de099a64c38768e2f6727007 332 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.2E-37 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 1.9E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 1.9E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 1.9E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 PRINTS PR01041 Methionyl-tRNA synthetase signature 384 395 1.9E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 1.9E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 PRINTS PR01041 Methionyl-tRNA synthetase signature 291 306 1.9E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 534 2.3E-184 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 SUPERFAMILY SSF47323 390 545 4.45E-36 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 SUPERFAMILY SSF57770 142 176 2.49E-12 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 Gene3D G3DSA:1.10.730.10 389 526 1.6E-27 T 12-10-2018 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 Gene3D G3DSA:2.20.28.20 142 176 2.5E-153 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 Pfam PF09334 tRNA synthetases class I (M) 8 396 5.8E-158 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 SUPERFAMILY SSF52374 6 387 1.24E-97 T 12-10-2018 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 545 39.395 T 12-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_888 5052e59c25967a73be187f3e38e1d9d4 555 Gene3D G3DSA:3.40.50.620 8 384 2.5E-153 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 160 181 2.1E-53 T 12-10-2018 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 250 276 2.1E-53 T 12-10-2018 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 2.1E-53 T 12-10-2018 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 318 330 2.1E-53 T 12-10-2018 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 113 133 2.1E-53 T 12-10-2018 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 228 249 2.1E-53 T 12-10-2018 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 85 110 2.1E-53 T 12-10-2018 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 67 124 4.3E-23 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 Pfam PF00361 Proton-conducting membrane transporter 136 428 4.2E-90 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 1.8E-10 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 61 85 1.8E-10 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 87 107 1.8E-10 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 268 290 1.8E-10 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 IM45_839 d49470ddcc161092e6703b3e6de7331f 616 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 613 1.0E-219 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_1355 8df5cc3e60e3501b4706cc8d0dac3db6 118 TIGRFAM TIGR00526 folB_dom: FolB domain 2 117 2.7E-34 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 IM45_1355 8df5cc3e60e3501b4706cc8d0dac3db6 118 Pfam PF02152 Dihydroneopterin aldolase 4 112 3.3E-30 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 IM45_1355 8df5cc3e60e3501b4706cc8d0dac3db6 118 Gene3D G3DSA:3.30.1130.10 1 118 5.9E-40 T 12-10-2018 IM45_1355 8df5cc3e60e3501b4706cc8d0dac3db6 118 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 3.3E-28 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 IM45_1355 8df5cc3e60e3501b4706cc8d0dac3db6 118 SUPERFAMILY SSF55620 2 115 5.0E-35 T 12-10-2018 IM45_1355 8df5cc3e60e3501b4706cc8d0dac3db6 118 SMART SM00905 4 114 1.6E-45 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 IM45_958 9fdb7ebc693d004a14acbef675f98359 265 PIRSF PIRSF005902 1 261 1.7E-75 T 12-10-2018 IPR001130 TatD family GO:0016788 IM45_958 9fdb7ebc693d004a14acbef675f98359 265 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 IM45_958 9fdb7ebc693d004a14acbef675f98359 265 Pfam PF01026 TatD related DNase 4 257 1.5E-74 T 12-10-2018 IPR001130 TatD family GO:0016788 IM45_958 9fdb7ebc693d004a14acbef675f98359 265 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 193 209 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 IM45_958 9fdb7ebc693d004a14acbef675f98359 265 SUPERFAMILY SSF51556 1 259 5.16E-81 T 12-10-2018 IPR032466 Metal-dependent hydrolase IM45_958 9fdb7ebc693d004a14acbef675f98359 265 Gene3D G3DSA:3.20.20.140 1 264 1.0E-93 T 12-10-2018 IM45_958 9fdb7ebc693d004a14acbef675f98359 265 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 128 138 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 IM45_958 9fdb7ebc693d004a14acbef675f98359 265 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 258 6.8E-90 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 SUPERFAMILY SSF54893 11 107 1.02E-31 T 12-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 110 156 7.9E-15 T 12-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 14 104 1.1E-27 T 12-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 Gene3D G3DSA:3.30.70.140 8 107 6.7E-33 T 12-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 Gene3D G3DSA:2.30.30.20 108 159 4.0E-21 T 12-10-2018 IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 13 158 8.0E-57 T 12-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 11 159 30.226 T 12-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 SUPERFAMILY SSF57825 108 157 5.1E-13 T 12-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily IM45_597 7618eca35cc1c2cfd7a74f82e1e8a013 163 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 16 101 1.0E-34 T 12-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal IM45_849 28fd7a1a36a511cb7abedc715c7b6824 161 Gene3D G3DSA:3.40.30.10 78 160 2.3E-22 T 12-10-2018 IM45_849 28fd7a1a36a511cb7abedc715c7b6824 161 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 118 136 - T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_849 28fd7a1a36a511cb7abedc715c7b6824 161 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 18 160 1.1E-49 T 12-10-2018 IM45_849 28fd7a1a36a511cb7abedc715c7b6824 161 Gene3D G3DSA:1.10.10.1590 8 77 5.3E-16 T 12-10-2018 IM45_849 28fd7a1a36a511cb7abedc715c7b6824 161 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 17 160 6.8E-52 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_849 28fd7a1a36a511cb7abedc715c7b6824 161 SUPERFAMILY SSF52833 10 160 4.58E-50 T 12-10-2018 IPR036249 Thioredoxin-like superfamily IM45_849 28fd7a1a36a511cb7abedc715c7b6824 161 PIRSF PIRSF000216 3 161 1.7E-52 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 SUPERFAMILY SSF110324 2 78 3.84E-33 T 12-10-2018 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 1.4E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.3E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.3E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.3E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 29 71 1.0E-14 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 Gene3D G3DSA:2.40.50.1030 6 91 2.9E-29 T 12-10-2018 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 Pfam PF01016 Ribosomal L27 protein 2 86 9.0E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1405 d8d5e3256a49c7ca9b460450516fbccd 91 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 89 27.736 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 Gene3D G3DSA:3.40.50.300 1 285 3.5E-134 T 12-10-2018 IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 1.4E-261 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 SUPERFAMILY SSF52317 289 541 1.23E-87 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 Pfam PF00117 Glutamine amidotransferase class-I 301 535 6.6E-62 T 12-10-2018 IPR017926 Glutamine amidotransferase IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 Gene3D G3DSA:3.40.50.880 287 545 1.1E-103 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 Pfam PF06418 CTP synthase N-terminus 5 266 1.3E-124 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 SUPERFAMILY SSF52540 2 266 1.16E-120 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_513 b4a1d5197729dd9bd394cb7b03faf046 545 Hamap MF_01227 CTP synthase [pyrG]. 3 540 50.905 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 Gene3D G3DSA:1.20.140.160 128 285 5.3E-15 T 12-10-2018 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 14 284 1.2E-125 T 12-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 PRINTS PR00046 Major sigma-70 factor signature 233 245 2.0E-18 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 PRINTS PR00046 Major sigma-70 factor signature 253 268 2.0E-18 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 PRINTS PR00046 Major sigma-70 factor signature 77 90 2.0E-18 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 PRINTS PR00046 Major sigma-70 factor signature 268 279 2.0E-18 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 280 3.4E-34 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 SUPERFAMILY SSF88659 200 284 6.73E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 SUPERFAMILY SSF88946 11 122 1.31E-39 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 Pfam PF04545 Sigma-70, region 4 229 280 1.4E-13 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 Gene3D G3DSA:1.20.120.1810 8 122 3.7E-28 T 12-10-2018 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 285 50.991 T 12-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 PIRSF PIRSF000770 2 286 1.3E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 Pfam PF04542 Sigma-70 region 2 53 122 1.8E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 IM45_143 f553b1b913ece1d5fdb26e8f4217224d 286 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 253 279 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1059 15791984014e9aab9cc96a34f9f15d6e 377 Pfam PF04055 Radical SAM superfamily 12 180 3.1E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 IM45_1059 15791984014e9aab9cc96a34f9f15d6e 377 SMART SM00729 7 224 2.4E-42 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 IM45_1059 15791984014e9aab9cc96a34f9f15d6e 377 Gene3D G3DSA:3.80.30.20 1 299 1.9E-89 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe IM45_1059 15791984014e9aab9cc96a34f9f15d6e 377 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 8 369 3.3E-121 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 IM45_1059 15791984014e9aab9cc96a34f9f15d6e 377 Pfam PF06969 HemN C-terminal domain 304 365 7.8E-8 T 12-10-2018 IPR010723 HemN, C-terminal IM45_1059 15791984014e9aab9cc96a34f9f15d6e 377 SUPERFAMILY SSF102114 6 377 6.93E-95 T 12-10-2018 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 SUPERFAMILY SSF50447 555 636 3.34E-22 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Gene3D G3DSA:2.40.30.10 783 879 5.5E-33 T 12-10-2018 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Gene3D G3DSA:3.30.56.50 2 50 2.4E-23 T 12-10-2018 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 ProSitePatterns PS01176 Initiation factor 2 signature. 832 854 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 SUPERFAMILY SSF46955 3 50 2.01E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 57 95 4.8E-15 T 12-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Gene3D G3DSA:2.40.30.10 553 670 1.6E-37 T 12-10-2018 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 384 540 7.1E-34 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Pfam PF03144 Elongation factor Tu domain 2 802 869 4.1E-7 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Pfam PF11987 Translation-initiation factor 2 666 771 9.8E-37 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Pfam PF00009 Elongation factor Tu GTP binding domain 386 542 2.0E-33 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Gene3D G3DSA:3.40.50.300 379 552 5.6E-70 T 12-10-2018 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 SUPERFAMILY SSF52156 661 788 1.15E-36 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 296 878 3.8E-278 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 SUPERFAMILY SSF52540 382 549 1.08E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 5.8E-8 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 306 354 1.1E-13 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Gene3D G3DSA:3.40.50.10050 676 782 7.1E-38 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 SUPERFAMILY SSF50447 782 877 7.86E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_1383 fbcb15ef2e71bbfe391b9be5000145ac 885 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 879 17.228 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Gene3D G3DSA:3.50.40.10 189 386 1.4E-69 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 783 41.003 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Pfam PF01588 Putative tRNA binding domain 45 135 1.7E-9 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SUPERFAMILY SSF46955 395 466 1.83E-15 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Pfam PF03483 B3/4 domain 203 376 3.4E-62 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SMART SM00874 394 462 5.5E-19 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Gene3D G3DSA:3.30.930.10 483 687 3.9E-59 T 12-10-2018 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SUPERFAMILY SSF54991 692 789 6.67E-22 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Pfam PF03484 tRNA synthetase B5 domain 397 462 3.9E-15 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Pfam PF03147 Ferredoxin-fold anticodon binding domain 696 789 1.0E-18 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SUPERFAMILY SSF56037 187 387 3.14E-68 T 12-10-2018 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Gene3D G3DSA:3.30.56.10 7 171 1.3E-47 T 12-10-2018 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Gene3D G3DSA:3.30.70.380 697 790 1.1E-20 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Gene3D G3DSA:3.30.56.10 392 466 2.1E-21 T 12-10-2018 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SMART SM00873 203 376 1.4E-81 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 2 789 2.9E-239 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 Gene3D G3DSA:2.40.50.140 39 145 1.3E-47 T 12-10-2018 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SUPERFAMILY SSF50249 35 179 5.14E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SMART SM00896 696 789 1.8E-25 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 IM45_1033 88b366a647801d65d027b6b6c30a98d1 790 SUPERFAMILY SSF55681 458 685 1.69E-52 T 12-10-2018 IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 Gene3D G3DSA:2.40.30.20 94 192 6.5E-23 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 Gene3D G3DSA:2.40.30.20 1 88 2.6E-30 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 4.5E-69 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 SUPERFAMILY SSF63380 93 198 1.53E-26 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 SUPERFAMILY SSF63380 1 88 8.16E-27 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 PIRSF PIRSF000498 1 211 4.6E-67 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 Pfam PF00677 Lumazine binding domain 3 87 1.9E-22 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_209 69b93c966cc423c5f6c37673964ef2a3 213 Pfam PF00677 Lumazine binding domain 100 185 5.5E-17 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_777 605e5d68c5b89648c595786c3d66fb71 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_777 605e5d68c5b89648c595786c3d66fb71 130 Gene3D G3DSA:3.30.1490.10 73 130 8.3E-23 T 12-10-2018 IM45_777 605e5d68c5b89648c595786c3d66fb71 130 SUPERFAMILY SSF56047 2 129 2.75E-45 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_777 605e5d68c5b89648c595786c3d66fb71 130 Pfam PF00410 Ribosomal protein S8 5 129 2.5E-46 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_777 605e5d68c5b89648c595786c3d66fb71 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 30.967 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_777 605e5d68c5b89648c595786c3d66fb71 130 Gene3D G3DSA:3.30.1370.30 2 72 2.8E-26 T 12-10-2018 IM45_1147 a17bec36c83d4fd37eede6c872bdcc5b 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1147 a17bec36c83d4fd37eede6c872bdcc5b 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 24.509 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1147 a17bec36c83d4fd37eede6c872bdcc5b 360 Pfam PF00953 Glycosyl transferase family 4 99 284 4.3E-35 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 IM45_1147 a17bec36c83d4fd37eede6c872bdcc5b 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 2.0E-145 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1147 a17bec36c83d4fd37eede6c872bdcc5b 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1147 a17bec36c83d4fd37eede6c872bdcc5b 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 70 80 2.9E-4 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 Gene3D G3DSA:3.30.160.40 221 306 7.8E-28 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 1.1E-42 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 1.1E-42 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 1.1E-42 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 1.1E-42 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 1.1E-42 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 Gene3D G3DSA:3.40.190.10 6 210 1.2E-75 T 12-10-2018 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 295 2.1E-21 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 SUPERFAMILY SSF53850 5 219 5.21E-77 T 12-10-2018 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 231 247 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 SUPERFAMILY SSF54782 220 308 6.02E-26 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 Gene3D G3DSA:3.40.190.10 103 202 1.2E-75 T 12-10-2018 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 297 36.584 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 PIRSF PIRSF001438 1 312 4.8E-111 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 212 2.1E-71 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_149 26d565fcabfc0d7055ff5ac11923e192 316 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 296 1.1E-110 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 IM45_873 b237acd077b83a3114d10635d6be2524 368 Gene3D G3DSA:3.30.470.20 129 353 2.9E-82 T 12-10-2018 IM45_873 b237acd077b83a3114d10635d6be2524 368 Pfam PF07478 D-ala D-ala ligase C-terminus 147 348 9.9E-71 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_873 b237acd077b83a3114d10635d6be2524 368 Gene3D G3DSA:3.30.1490.20 155 224 2.9E-82 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 IM45_873 b237acd077b83a3114d10635d6be2524 368 Gene3D G3DSA:3.40.50.20 2 128 1.1E-41 T 12-10-2018 IM45_873 b237acd077b83a3114d10635d6be2524 368 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 350 6.9E-106 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_873 b237acd077b83a3114d10635d6be2524 368 SUPERFAMILY SSF56059 140 357 1.06E-57 T 12-10-2018 IM45_873 b237acd077b83a3114d10635d6be2524 368 Pfam PF01820 D-ala D-ala ligase N-terminus 5 130 5.2E-29 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_873 b237acd077b83a3114d10635d6be2524 368 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 351 40.552 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_873 b237acd077b83a3114d10635d6be2524 368 PIRSF PIRSF039102 1 359 1.4E-128 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_873 b237acd077b83a3114d10635d6be2524 368 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 107 118 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_873 b237acd077b83a3114d10635d6be2524 368 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_873 b237acd077b83a3114d10635d6be2524 368 SUPERFAMILY SSF52440 3 139 4.6E-34 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Gene3D G3DSA:2.40.30.130 462 553 1.1E-9 T 12-10-2018 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Pfam PF02272 DHHA1 domain 734 873 2.9E-19 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 175.77 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 210 221 7.3E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 77 88 7.3E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 7.3E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 7.3E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 7.3E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 697 5.9E-17 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 855 3.4E-302 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 SUPERFAMILY SSF101353 257 465 9.29E-56 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Gene3D G3DSA:3.30.54.20 625 678 4.9E-44 T 12-10-2018 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Gene3D G3DSA:3.30.930.10 3 253 3.3E-114 T 12-10-2018 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 SUPERFAMILY SSF50447 457 553 7.77E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Pfam PF01411 tRNA synthetases class II (A) 8 556 1.4E-211 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 SMART SM00863 654 697 7.1E-20 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Gene3D G3DSA:3.10.310.40 765 875 2.0E-22 T 12-10-2018 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 SUPERFAMILY SSF55186 553 714 7.59E-47 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 Gene3D G3DSA:3.30.980.10 557 696 4.9E-44 T 12-10-2018 IM45_475 1efbc2ceaf7b62f9778cd83d8e774fd0 878 SUPERFAMILY SSF55681 5 256 4.22E-100 T 12-10-2018 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Pfam PF01624 MutS domain I 14 126 3.8E-41 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Gene3D G3DSA:3.40.50.300 573 858 3.6E-96 T 12-10-2018 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 691 707 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Pfam PF05190 MutS family domain IV 431 519 1.4E-25 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Gene3D G3DSA:1.10.1420.10 272 562 1.7E-100 T 12-10-2018 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 PIRSF PIRSF037677 6 841 7.4E-150 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Pfam PF05192 MutS domain III 276 562 7.3E-39 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 SUPERFAMILY SSF55271 4 121 1.11E-42 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Gene3D G3DSA:3.30.420.110 133 268 9.1E-36 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 SUPERFAMILY SSF52540 570 800 2.06E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Gene3D G3DSA:1.10.1420.10 390 506 1.7E-100 T 12-10-2018 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 SUPERFAMILY SSF48334 273 569 1.96E-84 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Pfam PF00488 MutS domain V 613 800 7.0E-84 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 13 852 0.0 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 SMART SM00534 610 797 1.4E-111 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 13 847 24.894 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Pfam PF05188 MutS domain II 134 258 1.5E-29 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 SUPERFAMILY SSF53150 120 272 3.14E-42 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 Gene3D G3DSA:3.40.1170.10 5 127 2.0E-50 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 IM45_483 c29372d144370dd2006d01bee1e7e4aa 862 SMART SM00533 289 594 6.8E-96 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 IM45_377 0747dafb829025c875b32e6347e40af6 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 173 41.498 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 IM45_377 0747dafb829025c875b32e6347e40af6 180 PIRSF PIRSF039093 1 176 1.5E-86 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 IM45_377 0747dafb829025c875b32e6347e40af6 180 SUPERFAMILY SSF56235 2 173 1.2E-55 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal IM45_377 0747dafb829025c875b32e6347e40af6 180 Gene3D G3DSA:3.60.20.10 1 174 4.5E-65 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal IM45_377 0747dafb829025c875b32e6347e40af6 180 Pfam PF00227 Proteasome subunit 2 169 2.6E-21 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 IM45_377 0747dafb829025c875b32e6347e40af6 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 173 1.4E-84 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 4 186 9.2E-71 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 SMART SM00072 3 189 2.6E-64 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 Pfam PF00625 Guanylate kinase 6 187 3.0E-57 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 Gene3D G3DSA:3.30.63.10 39 98 4.6E-67 T 12-10-2018 IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 SUPERFAMILY SSF52540 3 191 2.94E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 Gene3D G3DSA:3.40.50.300 8 185 4.6E-67 T 12-10-2018 IM45_260 e7a4f818665da4faf8d37cd2567dcd5a 209 Hamap MF_00328 Guanylate kinase [gmk]. 2 189 35.755 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00097 Anthranilate synthase component II signature 347 360 3.3E-5 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00097 Anthranilate synthase component II signature 262 273 3.3E-5 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00097 Anthranilate synthase component II signature 234 243 3.3E-5 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 Gene3D G3DSA:3.40.50.880 152 375 4.0E-72 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 SUPERFAMILY SSF52021 4 141 7.32E-56 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 372 7.3E-144 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 SMART SM01097 3 133 1.5E-87 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 SUPERFAMILY SSF52317 154 375 9.32E-61 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 Pfam PF00117 Glutamine amidotransferase class-I 195 370 5.7E-46 T 12-10-2018 IPR017926 Glutamine amidotransferase IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 4.5E-50 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 Gene3D G3DSA:3.50.30.20 2 151 5.2E-58 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 192 206 2.0E-36 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 245 2.0E-36 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 296 2.0E-36 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 262 278 2.0E-36 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 304 315 2.0E-36 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 376 47.645 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 347 360 2.1E-10 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 262 273 2.1E-10 T 12-10-2018 IM45_1231 d9a4e26c9074bcb0ce5999ab156fe81e 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 243 2.1E-10 T 12-10-2018 IM45_077 8738c7696d0afbb85d1b69b3f4f73576 135 Pfam PF06295 Protein of unknown function (DUF1043) 7 121 1.5E-41 T 12-10-2018 IPR009386 Protein of unknown function DUF1043 IM45_077 8738c7696d0afbb85d1b69b3f4f73576 135 PIRSF PIRSF006318 1 131 4.0E-45 T 12-10-2018 IPR009386 Protein of unknown function DUF1043 IM45_968 05a1193d4672fe080569411e7c550573 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 3.8E-5 T 12-10-2018 IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 SUPERFAMILY SSF51735 4 243 2.47E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_968 05a1193d4672fe080569411e7c550573 244 Gene3D G3DSA:3.40.50.720 1 244 3.6E-83 T 12-10-2018 IM45_968 05a1193d4672fe080569411e7c550573 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 7.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 7.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 7.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 7.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_968 05a1193d4672fe080569411e7c550573 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 1.1E-63 T 12-10-2018 IM45_968 05a1193d4672fe080569411e7c550573 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 6.6E-97 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_765 3fae84f027739ee557444268259be9f7 136 SUPERFAMILY SSF54686 3 133 4.32E-54 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_765 3fae84f027739ee557444268259be9f7 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 58 69 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_765 3fae84f027739ee557444268259be9f7 136 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 81 92 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_765 3fae84f027739ee557444268259be9f7 136 Gene3D G3DSA:3.90.1170.10 1 136 1.9E-54 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_765 3fae84f027739ee557444268259be9f7 136 PRINTS PR00060 Ribosomal protein L16 signature 23 35 1.2E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_765 3fae84f027739ee557444268259be9f7 136 PRINTS PR00060 Ribosomal protein L16 signature 87 116 1.2E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_765 3fae84f027739ee557444268259be9f7 136 PRINTS PR00060 Ribosomal protein L16 signature 41 52 1.2E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_765 3fae84f027739ee557444268259be9f7 136 PRINTS PR00060 Ribosomal protein L16 signature 57 86 1.2E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_765 3fae84f027739ee557444268259be9f7 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 7.3E-47 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 IM45_765 3fae84f027739ee557444268259be9f7 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 9.9E-58 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_765 3fae84f027739ee557444268259be9f7 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 133 37.347 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 4 423 43.95 T 12-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 8.8E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 188 210 8.8E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 167 182 8.8E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 221 233 8.8E-32 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 Gene3D G3DSA:1.10.240.10 228 330 2.9E-34 T 12-10-2018 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 SMART SM00363 357 419 0.0015 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 Pfam PF00579 tRNA synthetases class I (W and Y) 31 328 4.7E-85 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 Gene3D G3DSA:3.10.290.10 331 424 9.3E-26 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 Pfam PF01479 S4 domain 359 391 2.4E-5 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 Gene3D G3DSA:3.40.50.620 1 227 7.0E-89 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 423 1.7E-131 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 SUPERFAMILY SSF55174 327 423 6.28E-20 T 12-10-2018 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 SUPERFAMILY SSF52374 5 328 5.63E-102 T 12-10-2018 IM45_197 501e30e813b8cfb9d1e1bc0e297ca36d 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_1069 5131d473728a8538b6d174923a68b311 205 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 199 1.3E-38 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 90 6.0E-30 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 Gene3D G3DSA:2.40.500.20 91 204 2.8E-46 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 168 175 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 SUPERFAMILY SSF54719 95 203 5.5E-43 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 Gene3D G3DSA:1.10.287.990 20 90 9.0E-31 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 SUPERFAMILY SSF46609 1 90 9.69E-34 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 PIRSF PIRSF000349 1 204 1.1E-75 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 1.3E-24 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 1.3E-24 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.3E-24 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.3E-24 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1069 5131d473728a8538b6d174923a68b311 205 PRINTS PR01703 Manganese superoxide dismutase signature 166 178 1.3E-24 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 Gene3D G3DSA:3.30.1550.10 2 72 2.3E-34 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.4E-63 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.4E-28 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 SMART SM00649 9 141 1.2E-78 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 SUPERFAMILY SSF54747 3 73 1.07E-29 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 SUPERFAMILY SSF46906 68 141 1.1E-24 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.154 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 71 9.0E-13 T 12-10-2018 IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 4.5E-23 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 IM45_1097 db01d336ef95e9e7ef436abf5fa86246 142 Gene3D G3DSA:1.10.10.2720 73 142 1.5E-24 T 12-10-2018 IM45_258 a9c28512635efbcb81290351552f7dfa 141 Pfam PF01047 MarR family 34 90 1.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_258 a9c28512635efbcb81290351552f7dfa 141 SUPERFAMILY SSF46785 10 137 3.95E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_258 a9c28512635efbcb81290351552f7dfa 141 Gene3D G3DSA:1.10.10.10 2 140 4.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_258 a9c28512635efbcb81290351552f7dfa 141 SMART SM00347 27 126 3.5E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 Pfam PF00162 Phosphoglycerate kinase 8 373 5.3E-128 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 SUPERFAMILY SSF53748 5 383 1.3E-131 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 Gene3D G3DSA:3.40.50.1260 10 378 3.2E-143 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 Gene3D G3DSA:3.40.50.1260 165 373 3.2E-143 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 383 36.39 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PIRSF PIRSF000724 1 389 1.4E-124 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 3.7E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_1411 21d4e1a89741e0de2b577a01a4155387 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_644 d8f2d210858911b690dcb274b79073b7 230 Gene3D G3DSA:3.30.160.20 143 224 1.2E-18 T 12-10-2018 IM45_644 d8f2d210858911b690dcb274b79073b7 230 Pfam PF14622 Ribonuclease-III-like 19 139 2.6E-33 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 IM45_644 d8f2d210858911b690dcb274b79073b7 230 Pfam PF00035 Double-stranded RNA binding motif 155 222 2.7E-14 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain IM45_644 d8f2d210858911b690dcb274b79073b7 230 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 IM45_644 d8f2d210858911b690dcb274b79073b7 230 SMART SM00358 155 223 7.9E-21 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain IM45_644 d8f2d210858911b690dcb274b79073b7 230 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 28.929 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 IM45_644 d8f2d210858911b690dcb274b79073b7 230 Gene3D G3DSA:1.10.1520.10 2 142 1.6E-42 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 IM45_644 d8f2d210858911b690dcb274b79073b7 230 SMART SM00535 20 148 7.1E-53 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 IM45_644 d8f2d210858911b690dcb274b79073b7 230 SUPERFAMILY SSF54768 108 226 1.13E-27 T 12-10-2018 IM45_644 d8f2d210858911b690dcb274b79073b7 230 SUPERFAMILY SSF69065 4 158 1.67E-47 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 IM45_644 d8f2d210858911b690dcb274b79073b7 230 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 221 5.3E-69 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 IM45_110 f476d582a3e778c0b5597951b630ad92 387 Gene3D G3DSA:3.20.20.70 14 366 6.4E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_110 f476d582a3e778c0b5597951b630ad92 387 SUPERFAMILY SSF102114 37 363 3.01E-46 T 12-10-2018 IM45_110 f476d582a3e778c0b5597951b630ad92 387 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 4 366 1.1E-151 T 12-10-2018 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 IM45_110 f476d582a3e778c0b5597951b630ad92 387 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 258 361 2.8E-22 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 IM45_110 f476d582a3e778c0b5597951b630ad92 387 SMART SM00876 258 362 4.9E-31 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 IM45_542 b83e8cd75334d724c257ac616299262e 372 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 13 368 28.545 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_542 b83e8cd75334d724c257ac616299262e 372 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 19 366 1.6E-136 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_542 b83e8cd75334d724c257ac616299262e 372 Pfam PF01098 Cell cycle protein 20 366 1.2E-119 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_542 b83e8cd75334d724c257ac616299262e 372 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 323 347 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 SUPERFAMILY SSF109998 248 431 5.76E-37 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 Gene3D G3DSA:1.10.3120.10 116 419 7.6E-89 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 PIRSF PIRSF003095 1 435 4.7E-108 T 12-10-2018 IPR005215 Trigger factor GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 Hamap MF_00303 Trigger factor [tig]. 1 420 19.049 T 12-10-2018 IPR005215 Trigger factor GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 237 2.9E-10 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 TIGRFAM TIGR00115 tig: trigger factor 11 414 5.6E-119 T 12-10-2018 IPR005215 Trigger factor GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 SUPERFAMILY SSF102735 1 131 1.01E-33 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 3.6E-34 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 Gene3D G3DSA:3.30.70.1050 1 115 2.9E-33 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 262 414 2.0E-29 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 Gene3D G3DSA:3.10.50.40 150 246 7.6E-89 T 12-10-2018 IM45_611 b83c793f39f84b68241ec12dcbfa4cb3 436 SUPERFAMILY SSF54534 91 241 3.34E-29 T 12-10-2018 IM45_059 c28677631f7e1455fb588eb7b877b790 173 PRINTS PR01100 Shikimate kinase family signature 98 115 1.1E-27 T 12-10-2018 IM45_059 c28677631f7e1455fb588eb7b877b790 173 PRINTS PR01100 Shikimate kinase family signature 31 44 1.1E-27 T 12-10-2018 IM45_059 c28677631f7e1455fb588eb7b877b790 173 PRINTS PR01100 Shikimate kinase family signature 7 22 1.1E-27 T 12-10-2018 IM45_059 c28677631f7e1455fb588eb7b877b790 173 PRINTS PR01100 Shikimate kinase family signature 59 67 1.1E-27 T 12-10-2018 IM45_059 c28677631f7e1455fb588eb7b877b790 173 PRINTS PR01100 Shikimate kinase family signature 77 86 1.1E-27 T 12-10-2018 IM45_059 c28677631f7e1455fb588eb7b877b790 173 SUPERFAMILY SSF52540 4 170 1.44E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_059 c28677631f7e1455fb588eb7b877b790 173 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 IM45_059 c28677631f7e1455fb588eb7b877b790 173 Gene3D G3DSA:3.40.50.300 1 173 3.5E-54 T 12-10-2018 IM45_059 c28677631f7e1455fb588eb7b877b790 173 Pfam PF01202 Shikimate kinase 13 170 5.0E-54 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 IM45_059 c28677631f7e1455fb588eb7b877b790 173 Hamap MF_00109 Shikimate kinase [aroK]. 4 171 28.311 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 Hamap MF_01465 Protein translocase subunit SecY [secY]. 10 433 28.776 T 12-10-2018 IPR026593 Protein translocase subunit SecY IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 2.7E-92 T 12-10-2018 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 PIRSF PIRSF004557 12 439 7.9E-124 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 SUPERFAMILY SSF103491 15 424 6.15E-126 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 Gene3D G3DSA:1.10.3370.10 9 429 3.7E-156 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 429 5.2E-131 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 Pfam PF00344 SecY translocase 76 417 1.2E-112 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_789 6bdb7a429fd709d315c78b14c3c82bcf 439 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_262 cf7c77821ecbc763671895d83a019e4b 93 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.009 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_262 cf7c77821ecbc763671895d83a019e4b 93 SMART SM01409 8 61 1.1E-15 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 IM45_262 cf7c77821ecbc763671895d83a019e4b 93 SUPERFAMILY SSF63562 1 77 2.09E-22 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 IM45_262 cf7c77821ecbc763671895d83a019e4b 93 Gene3D G3DSA:3.90.940.10 1 92 4.3E-26 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 IM45_262 cf7c77821ecbc763671895d83a019e4b 93 Pfam PF01192 RNA polymerase Rpb6 10 59 2.6E-15 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 IM45_262 cf7c77821ecbc763671895d83a019e4b 93 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 3.5E-29 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_185 7786bd3fd7f854e6dd92fe95fafbf34e 316 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 IM45_185 7786bd3fd7f854e6dd92fe95fafbf34e 316 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 13 310 2.1E-98 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 IM45_185 7786bd3fd7f854e6dd92fe95fafbf34e 316 Gene3D G3DSA:3.20.20.70 1 316 2.0E-132 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_185 7786bd3fd7f854e6dd92fe95fafbf34e 316 TIGRFAM TIGR00874 talAB: transaldolase 2 316 2.1E-151 T 12-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 IM45_185 7786bd3fd7f854e6dd92fe95fafbf34e 316 ProSitePatterns PS00958 Transaldolase active site. 128 145 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 IM45_185 7786bd3fd7f854e6dd92fe95fafbf34e 316 SUPERFAMILY SSF51569 1 315 4.29E-111 T 12-10-2018 IM45_185 7786bd3fd7f854e6dd92fe95fafbf34e 316 Hamap MF_00492 Transaldolase [tal]. 1 316 51.449 T 12-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 Pfam PF08245 Mur ligase middle domain 124 304 1.8E-28 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 Gene3D G3DSA:3.40.1190.10 108 320 1.7E-80 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 342 418 2.6E-20 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 21 475 6.2E-169 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 SUPERFAMILY SSF53244 323 476 1.34E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 Pfam PF01225 Mur ligase family, catalytic domain 21 118 3.6E-28 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 SUPERFAMILY SSF51984 20 106 8.24E-28 T 12-10-2018 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 Gene3D G3DSA:3.40.50.720 20 107 7.1E-31 T 12-10-2018 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 19 481 41.816 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 Gene3D G3DSA:3.90.190.20 321 488 4.8E-46 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_1139 b549b05b46eaa21c9d9b8b87b9937051 490 SUPERFAMILY SSF53623 105 322 1.24E-70 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 SUPERFAMILY SSF54713 57 265 7.1E-43 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 SUPERFAMILY SSF46934 4 54 1.28E-15 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 Gene3D G3DSA:3.30.479.20 148 264 1.3E-37 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 Gene3D G3DSA:1.10.286.20 184 230 1.3E-37 T 12-10-2018 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 283 2.7E-94 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 Pfam PF00889 Elongation factor TS 73 265 3.0E-56 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 Hamap MF_00050 Elongation factor Ts [tsf]. 1 282 60.164 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 Gene3D G3DSA:3.30.479.20 57 143 2.4E-26 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 IM45_1167 aedd40a05395d3225ac62e130d2b7bb1 283 Gene3D G3DSA:1.10.8.10 1 56 4.4E-23 T 12-10-2018 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 340 1.3E-149 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 Pfam PF03462 PCRF domain 8 196 3.7E-52 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 SMART SM00937 58 172 1.7E-50 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 SUPERFAMILY SSF75620 3 341 2.09E-124 T 12-10-2018 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 Pfam PF00472 RF-1 domain 206 314 3.9E-38 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 Gene3D G3DSA:3.30.160.20 203 298 1.2E-93 T 12-10-2018 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 222 238 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 342 35.232 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 Gene3D G3DSA:1.20.58.410 1 93 7.2E-18 T 12-10-2018 IM45_349 66fb3a83c68d4d064ad59ae06f0ab37d 342 Gene3D G3DSA:3.30.70.1660 107 335 1.2E-93 T 12-10-2018 IM45_065 0db5790384f0d4a6d858c13665ba085e 457 SUPERFAMILY SSF103473 17 454 2.22E-67 T 12-10-2018 IPR036259 MFS transporter superfamily IM45_065 0db5790384f0d4a6d858c13665ba085e 457 Gene3D G3DSA:1.20.1250.20 17 456 7.8E-65 T 12-10-2018 IM45_065 0db5790384f0d4a6d858c13665ba085e 457 ProSitePatterns PS00216 Sugar transport proteins signature 1. 312 329 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 IM45_065 0db5790384f0d4a6d858c13665ba085e 457 Pfam PF00083 Sugar (and other) transporter 29 454 1.1E-40 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 330 8.9E-117 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 225 253 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Gene3D G3DSA:2.160.10.10 100 309 6.8E-64 T 12-10-2018 IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 23 89 4.5E-20 T 12-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Gene3D G3DSA:3.40.1390.10 1 99 4.9E-32 T 12-10-2018 IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 5 326 34.155 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 SUPERFAMILY SSF51161 33 316 3.39E-82 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 258 285 0.0028 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 179 2.2E-8 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 255 3.9E-8 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 130 2.0E-4 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_1185 299de1065b6b2b2cf6d11282553a8d2a 346 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 100 128 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 IM45_837 7e025dc4b949a2367fb3851653f3be5d 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 94 4.1E-19 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like IM45_837 7e025dc4b949a2367fb3851653f3be5d 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 100 18.079 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 IM45_1285 c214b0af8cc910ebdb827da8594efba8 421 SMART SM00646 228 387 2.3E-61 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 IM45_1285 c214b0af8cc910ebdb827da8594efba8 421 Gene3D G3DSA:2.60.40.3500 19 131 1.3E-13 T 12-10-2018 IM45_1285 c214b0af8cc910ebdb827da8594efba8 421 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 168 386 5.4E-45 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 IM45_1285 c214b0af8cc910ebdb827da8594efba8 421 Gene3D G3DSA:3.40.630.40 157 397 1.6E-65 T 12-10-2018 IM45_1285 c214b0af8cc910ebdb827da8594efba8 421 Pfam PF11741 AMIN domain 36 121 4.6E-8 T 12-10-2018 IPR021731 AMIN domain IM45_1285 c214b0af8cc910ebdb827da8594efba8 421 SUPERFAMILY SSF53187 166 390 1.0E-48 T 12-10-2018 IM45_397 0739c8afb3e06a859391e756442b5ea1 193 SUPERFAMILY SSF88713 1 192 1.22E-56 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 IM45_397 0739c8afb3e06a859391e756442b5ea1 193 Gene3D G3DSA:3.20.20.370 1 192 4.1E-60 T 12-10-2018 IM45_397 0739c8afb3e06a859391e756442b5ea1 193 Pfam PF04748 Divergent polysaccharide deacetylase 1 191 9.5E-64 T 12-10-2018 IPR006837 Divergent polysaccharide deacetylase IM45_389 09cc34c41b9f4236db3e0954156525c2 339 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 160 8.5E-46 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 Gene3D G3DSA:3.40.50.720 1 190 9.6E-52 T 12-10-2018 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 SUPERFAMILY SSF48179 183 334 1.63E-54 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 PIRSF PIRSF000114 1 335 3.3E-99 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 SUPERFAMILY SSF51735 7 181 4.62E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_389 09cc34c41b9f4236db3e0954156525c2 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 3.3E-40 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 3.3E-40 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 3.3E-40 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 3.3E-40 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 3.3E-40 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 3.3E-40 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 Gene3D G3DSA:1.10.1040.10 192 339 2.6E-50 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 322 2.5E-50 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_389 09cc34c41b9f4236db3e0954156525c2 339 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 325 36.569 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 362 3.8E-152 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 Gene3D G3DSA:1.10.150.300 113 200 9.1E-143 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 42.33 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 SUPERFAMILY SSF81271 279 359 2.4E-34 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 Gene3D G3DSA:3.10.20.30 48 361 9.1E-143 T 12-10-2018 IPR012675 Beta-grasp domain superfamily IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 3.6E-37 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 Pfam PF01926 50S ribosome-binding GTPase 5 115 1.3E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 SUPERFAMILY SSF52540 3 301 6.22E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 PIRSF PIRSF006641 1 363 1.0E-146 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.1E-29 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.1E-29 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.1E-29 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.1E-29 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_676 62fc2a7a1b546f7633c924402a50cb2c 363 Gene3D G3DSA:3.40.50.300 3 278 9.1E-143 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:1.10.1790.20 1135 1314 1.4E-60 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.0E-88 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 1.6E-77 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:1.10.274.100 490 637 2.0E-32 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 5.1E-19 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:1.10.132.30 638 790 1.8E-65 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1374 18.947 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 5.8E-29 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Pfam PF00623 RNA polymerase Rpb1, domain 2 389 485 7.8E-27 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 394 1.1E-7 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1367 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 SUPERFAMILY SSF64484 16 1364 0.0 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:2.40.50.100 1151 1215 1.4E-60 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:2.40.50.100 1023 1126 8.5E-29 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 SMART SM00663 235 514 3.2E-183 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:2.40.50.100 948 1022 3.9E-23 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:1.10.40.90 374 416 6.2E-22 T 12-10-2018 IM45_1107 dce3aacd2f0c6907db0448adedc7d4f6 1406 Gene3D G3DSA:1.10.150.390 1316 1376 2.5E-28 T 12-10-2018 IM45_902 ebb2a92a23985fd9406671acc5e01a32 359 Gene3D G3DSA:3.40.640.10 53 257 1.9E-126 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_902 ebb2a92a23985fd9406671acc5e01a32 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 8 352 1.7E-113 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 IM45_902 ebb2a92a23985fd9406671acc5e01a32 359 Pfam PF00155 Aminotransferase class I and II 46 350 2.6E-54 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 IM45_902 ebb2a92a23985fd9406671acc5e01a32 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 210 219 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 IM45_902 ebb2a92a23985fd9406671acc5e01a32 359 SUPERFAMILY SSF53383 27 352 6.93E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_902 ebb2a92a23985fd9406671acc5e01a32 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 6 354 51.332 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 IM45_902 ebb2a92a23985fd9406671acc5e01a32 359 Gene3D G3DSA:3.90.1150.10 6 345 1.9E-126 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Pfam PF00679 Elongation factor G C-terminus 399 479 3.9E-19 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Gene3D G3DSA:3.30.70.3380 368 478 3.9E-39 T 12-10-2018 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 168 5.2E-19 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.3E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.3E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.3E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 PRINTS PR00315 GTP-binding elongation factor signature 6 19 1.3E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.3E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Gene3D G3DSA:3.30.70.870 286 367 4.2E-34 T 12-10-2018 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 TIGRFAM TIGR01393 lepA: elongation factor 4 3 594 8.5E-287 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Gene3D G3DSA:3.40.50.300 1 185 3.7E-70 T 12-10-2018 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 1.0E-52 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Gene3D G3DSA:2.40.30.10 186 285 2.1E-31 T 12-10-2018 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Pfam PF03144 Elongation factor Tu domain 2 205 275 7.5E-9 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 286.703 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 SUPERFAMILY SSF52540 2 234 6.86E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Pfam PF06421 GTP-binding protein LepA C-terminus 487 592 5.3E-47 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 Gene3D G3DSA:3.30.70.2570 479 553 3.9E-30 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 SUPERFAMILY SSF54980 292 370 1.26E-17 T 12-10-2018 IPR035647 EF-G domain III/V-like IM45_648 e6805b73cbc4bcd1b8ba03f77f834ad9 599 SUPERFAMILY SSF54980 399 493 3.31E-23 T 12-10-2018 IPR035647 EF-G domain III/V-like IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Gene3D G3DSA:1.10.460.10 160 565 8.6E-149 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 SMART SM00437 267 524 3.8E-98 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 631 3.8E-233 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 727 50.364 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Gene3D G3DSA:2.20.25.10 803 858 5.0E-27 T 12-10-2018 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Pfam PF01751 Toprim domain 5 137 1.8E-30 T 12-10-2018 IPR006171 TOPRIM domain IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Gene3D G3DSA:1.10.290.10 275 399 8.6E-149 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 SUPERFAMILY SSF56712 3 605 9.55E-184 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain IM45_694 081e1de18d264aff1b5ba443dff006a2 865 SUPERFAMILY SSF57783 740 802 1.6E-17 T 12-10-2018 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Gene3D G3DSA:3.40.50.140 1 158 1.9E-61 T 12-10-2018 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 SMART SM00436 128 216 3.6E-41 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 304 318 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Pfam PF01131 DNA topoisomerase 156 562 6.1E-111 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 SMART SM00493 3 127 9.0E-27 T 12-10-2018 IPR006171 TOPRIM domain IM45_694 081e1de18d264aff1b5ba443dff006a2 865 SUPERFAMILY SSF57783 806 857 1.51E-20 T 12-10-2018 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Pfam PF08272 Topoisomerase I zinc-ribbon-like 819 857 7.4E-22 T 12-10-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Pfam PF08272 Topoisomerase I zinc-ribbon-like 753 788 6.8E-8 T 12-10-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 101 114 1.4E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 1.4E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 487 501 1.4E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 385 401 1.4E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 309 318 1.4E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 705 739 2.0E-8 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 595 619 0.002 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 SUPERFAMILY SSF57783 698 738 1.29E-5 T 12-10-2018 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Gene3D G3DSA:2.70.20.10 208 470 8.6E-149 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Gene3D G3DSA:3.30.65.10 699 739 3.9E-5 T 12-10-2018 IM45_694 081e1de18d264aff1b5ba443dff006a2 865 Gene3D G3DSA:3.30.65.10 740 802 1.3E-26 T 12-10-2018 IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 SUPERFAMILY SSF56281 2 252 2.1E-57 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 166 251 7.1E-17 T 12-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 Pfam PF00753 Metallo-beta-lactamase superfamily 16 165 6.0E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 PIRSF PIRSF005457 1 251 2.9E-80 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 Gene3D G3DSA:3.60.15.10 1 251 3.9E-81 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 251 40.302 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 SMART SM00849 12 165 3.0E-29 T 12-10-2018 IPR001279 Metallo-beta-lactamase IM45_1051 bf253dc7103c4e07ed25f0ae5cad1802 254 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 5 251 5.7E-89 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 IM45_029 5a07487527e9ad64b916568a85da58c4 537 Gene3D G3DSA:3.40.449.10 19 229 5.7E-217 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 IM45_029 5a07487527e9ad64b916568a85da58c4 537 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 537 50.371 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 IM45_029 5a07487527e9ad64b916568a85da58c4 537 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 486 2.7E-196 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 IM45_029 5a07487527e9ad64b916568a85da58c4 537 Gene3D G3DSA:3.90.228.20 230 518 5.7E-217 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 IM45_029 5a07487527e9ad64b916568a85da58c4 537 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 260 275 - T 12-10-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 IM45_029 5a07487527e9ad64b916568a85da58c4 537 SUPERFAMILY SSF53795 224 521 8.01E-113 T 12-10-2018 IM45_029 5a07487527e9ad64b916568a85da58c4 537 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 5 536 1.2E-246 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 IM45_029 5a07487527e9ad64b916568a85da58c4 537 Gene3D G3DSA:2.170.8.10 43 345 5.7E-217 T 12-10-2018 IM45_029 5a07487527e9ad64b916568a85da58c4 537 PIRSF PIRSF006294 2 537 4.8E-211 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 IM45_029 5a07487527e9ad64b916568a85da58c4 537 SUPERFAMILY SSF68923 5 222 4.71E-82 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 SUPERFAMILY SSF54631 95 203 2.91E-23 T 12-10-2018 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 482 80.393 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 SMART SM00116 158 206 5.9E-7 T 12-10-2018 IPR000644 CBS domain IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 SMART SM00116 96 144 6.5E-6 T 12-10-2018 IPR000644 CBS domain IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 SUPERFAMILY SSF51412 1 473 7.46E-119 T 12-10-2018 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 Gene3D G3DSA:3.20.20.70 1 482 1.3E-198 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 SMART SM01240 7 469 9.4E-293 T 12-10-2018 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 PIRSF PIRSF000130 1 483 5.0E-192 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 450 2.4E-187 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 Pfam PF00571 CBS domain 96 140 3.7E-7 T 12-10-2018 IPR000644 CBS domain IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 Pfam PF00571 CBS domain 149 202 0.001 T 12-10-2018 IPR000644 CBS domain IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 469 2.2E-157 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 IM45_1429 07c478aed63e11b39d45e3cd443a2783 483 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Gene3D G3DSA:1.10.1030.10 404 553 2.9E-49 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.4E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.4E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.4E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.4E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.4E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.4E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.4E-64 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SUPERFAMILY SSF48108 396 554 7.32E-52 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SMART SM01096 424 547 3.6E-68 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 710 724 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Gene3D G3DSA:3.40.50.20 554 663 4.2E-48 T 12-10-2018 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SUPERFAMILY SSF52440 1 127 3.17E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SUPERFAMILY SSF52335 941 1076 1.03E-22 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SUPERFAMILY SSF56059 128 401 9.02E-107 T 12-10-2018 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SMART SM00851 959 1047 2.1E-8 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Gene3D G3DSA:3.40.50.1380 940 1078 8.4E-24 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 4.8E-73 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 878 9.5E-35 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Gene3D G3DSA:3.30.470.20 119 403 2.0E-127 T 12-10-2018 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Gene3D G3DSA:3.40.50.20 1 116 1.6E-49 T 12-10-2018 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 1.4E-38 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SUPERFAMILY SSF56059 674 937 9.19E-96 T 12-10-2018 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Gene3D G3DSA:3.30.470.20 666 939 1.4E-115 T 12-10-2018 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Pfam PF02142 MGS-like domain 960 1046 9.3E-9 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 SUPERFAMILY SSF52440 557 676 2.3E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1057 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1233 c6e8ae349b1b3291e6f132bcf5297c14 1089 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1068 12.664 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_1332 6f24f3c9fa2bc20339b93e9a937c311e 184 Pfam PF00719 Inorganic pyrophosphatase 18 173 5.7E-53 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 IM45_1332 6f24f3c9fa2bc20339b93e9a937c311e 184 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 67 73 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 IM45_1332 6f24f3c9fa2bc20339b93e9a937c311e 184 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 175 36.102 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 IM45_1332 6f24f3c9fa2bc20339b93e9a937c311e 184 Gene3D G3DSA:3.90.80.10 2 177 3.2E-66 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 IM45_1332 6f24f3c9fa2bc20339b93e9a937c311e 184 SUPERFAMILY SSF50324 6 174 8.37E-63 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 IM45_1191 60817013c06da632e469eea242bc5e12 1152 Gene3D G3DSA:3.20.20.140 1 254 1.6E-79 T 12-10-2018 IM45_1191 60817013c06da632e469eea242bc5e12 1152 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 1 1023 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1191 60817013c06da632e469eea242bc5e12 1152 Pfam PF01336 OB-fold nucleic acid binding domain 987 1063 1.2E-6 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 IM45_1191 60817013c06da632e469eea242bc5e12 1152 SMART SM00481 1 58 2.7E-8 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal IM45_1191 60817013c06da632e469eea242bc5e12 1152 Gene3D G3DSA:2.40.50.140 973 1066 1.2E-8 T 12-10-2018 IM45_1191 60817013c06da632e469eea242bc5e12 1152 Pfam PF02811 PHP domain 2 156 1.2E-33 T 12-10-2018 IPR004013 PHP domain GO:0003824 IM45_1191 60817013c06da632e469eea242bc5e12 1152 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 275 717 4.4E-174 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1191 60817013c06da632e469eea242bc5e12 1152 Gene3D G3DSA:1.10.10.1600 417 494 4.6E-30 T 12-10-2018 IM45_1191 60817013c06da632e469eea242bc5e12 1152 Pfam PF14579 Helix-hairpin-helix motif 792 881 4.1E-23 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1191 60817013c06da632e469eea242bc5e12 1152 SUPERFAMILY SSF89550 3 247 4.32E-11 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 176 216 2.4E-18 T 12-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 PIRSF PIRSF000190 1 216 6.0E-80 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 Gene3D G3DSA:2.30.110.10 18 216 1.4E-72 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 216 5.2E-88 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 SUPERFAMILY SSF50475 19 216 1.01E-61 T 12-10-2018 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 186 199 - T 12-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 48 120 1.2E-20 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 IM45_199 8a2f7508161453cf3900ddc003730ac9 216 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 14 216 36.539 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 IM45_504 8b26855af6a3091432282a04322e8bec 598 Gene3D G3DSA:3.40.50.80 444 598 1.3E-56 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 524 540 1.3E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 493 504 1.3E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 547 555 1.3E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 267 277 1.3E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 385 392 1.3E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 480 489 1.3E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 455 474 1.3E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 Hamap MF_01541 Sulfite reductase [NADPH] flavoprotein alpha-component [cysJ]. 4 598 47.94 T 12-10-2018 IPR029758 Sulphite reductase [NADPH] flavoprotein, alpha chain, Proteobacteria GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_504 8b26855af6a3091432282a04322e8bec 598 SUPERFAMILY SSF63380 225 445 1.46E-62 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel IM45_504 8b26855af6a3091432282a04322e8bec 598 PIRSF PIRSF000207 1 598 1.5E-248 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_504 8b26855af6a3091432282a04322e8bec 598 Gene3D G3DSA:3.40.50.360 53 214 6.5E-46 T 12-10-2018 IPR029039 Flavoprotein-like superfamily IM45_504 8b26855af6a3091432282a04322e8bec 598 Gene3D G3DSA:1.20.990.10 277 383 5.5E-74 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00369 Flavodoxin signature 109 120 1.0E-15 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00369 Flavodoxin signature 165 184 1.0E-15 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00369 Flavodoxin signature 61 74 1.0E-15 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 PRINTS PR00369 Flavodoxin signature 141 151 1.0E-15 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 Gene3D G3DSA:2.40.30.10 229 438 5.5E-74 T 12-10-2018 IM45_504 8b26855af6a3091432282a04322e8bec 598 Pfam PF00258 Flavodoxin 62 190 1.3E-30 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 IM45_504 8b26855af6a3091432282a04322e8bec 598 SUPERFAMILY SSF52218 60 206 1.18E-43 T 12-10-2018 IPR029039 Flavoprotein-like superfamily IM45_504 8b26855af6a3091432282a04322e8bec 598 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 12 598 5.9E-251 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_504 8b26855af6a3091432282a04322e8bec 598 Pfam PF00667 FAD binding domain 230 423 5.1E-32 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 Pfam PF00175 Oxidoreductase NAD-binding domain 456 562 2.6E-19 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 IM45_504 8b26855af6a3091432282a04322e8bec 598 SUPERFAMILY SSF52343 443 598 3.01E-48 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain IM45_347 c46f63d2456cae9e2a1f3698f8b4b7a4 578 Pfam PF01368 DHH family 71 207 2.0E-8 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 IM45_347 c46f63d2456cae9e2a1f3698f8b4b7a4 578 Gene3D G3DSA:2.40.50.460 457 576 9.5E-6 T 12-10-2018 IM45_347 c46f63d2456cae9e2a1f3698f8b4b7a4 578 Gene3D G3DSA:3.90.1640.30 45 324 1.6E-80 T 12-10-2018 IM45_347 c46f63d2456cae9e2a1f3698f8b4b7a4 578 Pfam PF02272 DHHA1 domain 323 449 9.1E-20 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 IM45_347 c46f63d2456cae9e2a1f3698f8b4b7a4 578 Gene3D G3DSA:3.10.310.30 327 455 1.0E-28 T 12-10-2018 IM45_347 c46f63d2456cae9e2a1f3698f8b4b7a4 578 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 23 571 1.1E-144 T 12-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 IM45_347 c46f63d2456cae9e2a1f3698f8b4b7a4 578 SUPERFAMILY SSF64182 47 461 1.83E-102 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily IM45_1211 642bf0729bf82d1395a636af24efda86 210 ProSitePatterns PS00042 Crp-type HTH domain signature. 168 191 - T 12-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 IM45_1211 642bf0729bf82d1395a636af24efda86 210 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 71 89 - T 12-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site IM45_1211 642bf0729bf82d1395a636af24efda86 210 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 5.3E-21 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain IM45_1211 642bf0729bf82d1395a636af24efda86 210 Gene3D G3DSA:1.10.10.10 139 207 1.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_1211 642bf0729bf82d1395a636af24efda86 210 Gene3D G3DSA:2.60.120.10 10 138 9.2E-42 T 12-10-2018 IPR014710 RmlC-like jelly roll fold IM45_1211 642bf0729bf82d1395a636af24efda86 210 SMART SM00100 2 122 5.0E-23 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain IM45_1211 642bf0729bf82d1395a636af24efda86 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 197 2.3E-9 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 IM45_1211 642bf0729bf82d1395a636af24efda86 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 166 182 2.3E-9 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 IM45_1211 642bf0729bf82d1395a636af24efda86 210 SUPERFAMILY SSF46785 139 207 6.04E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_1211 642bf0729bf82d1395a636af24efda86 210 SUPERFAMILY SSF51206 8 137 6.02E-33 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like IM45_1211 642bf0729bf82d1395a636af24efda86 210 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 30 46 - T 12-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site IM45_1211 642bf0729bf82d1395a636af24efda86 210 SMART SM00419 160 208 2.4E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 IM45_1211 642bf0729bf82d1395a636af24efda86 210 Pfam PF00325 Bacterial regulatory proteins, crp family 166 197 1.9E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 IM45_1219 865644f69999fafdc2f322d78721836d 370 Gene3D G3DSA:1.10.287.110 1 107 9.1E-36 T 12-10-2018 IPR036869 Chaperone J-domain superfamily IM45_1219 865644f69999fafdc2f322d78721836d 370 SUPERFAMILY SSF46565 1 101 3.14E-35 T 12-10-2018 IPR036869 Chaperone J-domain superfamily IM45_1219 865644f69999fafdc2f322d78721836d 370 Pfam PF00226 DnaJ domain 5 67 4.2E-28 T 12-10-2018 IPR001623 DnaJ domain IM45_1219 865644f69999fafdc2f322d78721836d 370 Pfam PF01556 DnaJ C terminal domain 112 324 3.4E-44 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal IM45_1219 865644f69999fafdc2f322d78721836d 370 SUPERFAMILY SSF57938 125 202 9.29E-22 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily IM45_1219 865644f69999fafdc2f322d78721836d 370 PRINTS PR00625 DnaJ domain signature 7 25 1.3E-31 T 12-10-2018 IPR001623 DnaJ domain IM45_1219 865644f69999fafdc2f322d78721836d 370 PRINTS PR00625 DnaJ domain signature 25 40 1.3E-31 T 12-10-2018 IPR001623 DnaJ domain IM45_1219 865644f69999fafdc2f322d78721836d 370 PRINTS PR00625 DnaJ domain signature 42 62 1.3E-31 T 12-10-2018 IPR001623 DnaJ domain IM45_1219 865644f69999fafdc2f322d78721836d 370 PRINTS PR00625 DnaJ domain signature 62 81 1.3E-31 T 12-10-2018 IPR001623 DnaJ domain IM45_1219 865644f69999fafdc2f322d78721836d 370 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 12-10-2018 IPR018253 DnaJ domain, conserved site IM45_1219 865644f69999fafdc2f322d78721836d 370 Gene3D G3DSA:2.60.260.20 108 240 7.4E-37 T 12-10-2018 IM45_1219 865644f69999fafdc2f322d78721836d 370 Gene3D G3DSA:2.10.230.10 138 198 7.4E-37 T 12-10-2018 IM45_1219 865644f69999fafdc2f322d78721836d 370 SMART SM00271 4 62 4.1E-32 T 12-10-2018 IPR001623 DnaJ domain IM45_1219 865644f69999fafdc2f322d78721836d 370 SUPERFAMILY SSF49493 250 335 1.44E-20 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 IM45_1219 865644f69999fafdc2f322d78721836d 370 Gene3D G3DSA:2.60.260.20 245 324 1.9E-28 T 12-10-2018 IM45_1219 865644f69999fafdc2f322d78721836d 370 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 364 40.328 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 IM45_1219 865644f69999fafdc2f322d78721836d 370 SUPERFAMILY SSF49493 106 258 3.01E-21 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 IM45_1219 865644f69999fafdc2f322d78721836d 370 Pfam PF00684 DnaJ central domain 138 198 1.2E-13 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 IM45_1219 865644f69999fafdc2f322d78721836d 370 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 341 5.4E-135 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 IM45_429 5d2f1e6fbc413cbf95579cdb8a25375f 244 Gene3D G3DSA:3.40.630.30 1 238 3.3E-54 T 12-10-2018 IM45_429 5d2f1e6fbc413cbf95579cdb8a25375f 244 SUPERFAMILY SSF55729 18 229 4.12E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase IM45_429 5d2f1e6fbc413cbf95579cdb8a25375f 244 Pfam PF00583 Acetyltransferase (GNAT) family 118 222 3.6E-9 T 12-10-2018 IPR000182 GNAT domain IM45_429 5d2f1e6fbc413cbf95579cdb8a25375f 244 Hamap MF_02027 dTDP-fucosamine acetyltransferase [wecD]. 44 238 40.286 T 12-10-2018 IPR012752 dTDP-fucosamine acetyltransferase WecD GO:0008080|GO:0009246 MetaCyc: PWY-7315 IM45_1415 7517bf929dc39bce8139d86956229bd9 219 SUPERFAMILY SSF100950 2 146 9.21E-44 T 12-10-2018 IPR037171 NagB/RpiA transferase-like IM45_1415 7517bf929dc39bce8139d86956229bd9 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 215 2.1E-63 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 IM45_1415 7517bf929dc39bce8139d86956229bd9 219 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 218 31.597 T 12-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 IM45_1415 7517bf929dc39bce8139d86956229bd9 219 Gene3D G3DSA:3.30.70.260 125 197 1.6E-70 T 12-10-2018 IM45_1415 7517bf929dc39bce8139d86956229bd9 219 SUPERFAMILY SSF75445 127 199 1.44E-21 T 12-10-2018 IM45_1415 7517bf929dc39bce8139d86956229bd9 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 214 3.8E-54 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 IM45_1415 7517bf929dc39bce8139d86956229bd9 219 Gene3D G3DSA:3.40.50.1360 7 208 1.6E-70 T 12-10-2018 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 SUPERFAMILY SSF143800 1 66 5.89E-28 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 1.7E-30 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 Pfam PF01197 Ribosomal protein L31 1 64 1.3E-29 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 PRINTS PR01249 Ribosomal protein L31 signature 46 64 6.3E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.3E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 PRINTS PR01249 Ribosomal protein L31 signature 31 46 6.3E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 28.404 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_372 896dd61548c65e5e2927b9754bd0d045 71 Gene3D G3DSA:2.30.170.50 1 70 9.2E-31 T 12-10-2018 IM45_1365 46b9c22ba49f601517e9dcc8ea330146 275 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 206 261 1.0E-16 T 12-10-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 IM45_1365 46b9c22ba49f601517e9dcc8ea330146 275 Gene3D G3DSA:3.60.21.10 6 268 4.1E-66 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like IM45_1365 46b9c22ba49f601517e9dcc8ea330146 275 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 15 261 37.314 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 IM45_1365 46b9c22ba49f601517e9dcc8ea330146 275 Pfam PF00149 Calcineurin-like phosphoesterase 15 206 6.4E-16 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 IM45_1365 46b9c22ba49f601517e9dcc8ea330146 275 SUPERFAMILY SSF56300 15 270 1.08E-56 T 12-10-2018 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 13 459 9.2E-100 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 Gene3D G3DSA:1.20.120.430 124 459 7.5E-99 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 Gene3D G3DSA:3.40.50.300 220 387 7.5E-99 T 12-10-2018 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 PRINTS PR00449 Transforming protein P21 ras signature 220 241 4.9E-5 T 12-10-2018 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 PRINTS PR00449 Transforming protein P21 ras signature 330 343 4.9E-5 T 12-10-2018 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 SUPERFAMILY SSF52540 73 376 1.43E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 Pfam PF12631 MnmE helical domain 125 456 2.6E-53 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 Pfam PF01926 50S ribosome-binding GTPase 221 340 4.1E-27 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 219 374 6.9E-22 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 7 459 31.893 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 Gene3D G3DSA:3.30.1360.120 2 123 1.0E-35 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 IM45_320 aaf23bfcdcfb98a2fecde4215566d5f6 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 8 122 3.5E-33 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 SUPERFAMILY SSF48163 299 461 2.22E-41 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 Gene3D G3DSA:1.10.10.350 367 467 4.0E-21 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 Gene3D G3DSA:3.40.50.620 1 314 2.9E-129 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 SUPERFAMILY SSF52374 3 296 4.29E-108 T 12-10-2018 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 305 2.4E-110 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 464 1.2E-189 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 461 31.662 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 5.1E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 203 5.1E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 179 189 5.1E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 5.1E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_1011 11e5d663aa5edb807b22bec64323ee4d 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 5.1E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_1153 d1e07896967d8a0ab32160ac80429568 580 SUPERFAMILY SSF56601 228 561 1.56E-81 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like IM45_1153 d1e07896967d8a0ab32160ac80429568 580 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 12 563 43.901 T 12-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_1153 d1e07896967d8a0ab32160ac80429568 580 Gene3D G3DSA:3.90.1310.30 52 228 4.4E-42 T 12-10-2018 IM45_1153 d1e07896967d8a0ab32160ac80429568 580 Gene3D G3DSA:3.40.710.10 289 469 1.3E-100 T 12-10-2018 IM45_1153 d1e07896967d8a0ab32160ac80429568 580 SUPERFAMILY SSF56519 56 226 2.35E-43 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 IM45_1153 d1e07896967d8a0ab32160ac80429568 580 Gene3D G3DSA:3.30.450.330 230 543 1.3E-100 T 12-10-2018 IM45_1153 d1e07896967d8a0ab32160ac80429568 580 Pfam PF00905 Penicillin binding protein transpeptidase domain 253 547 1.3E-75 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 IM45_1153 d1e07896967d8a0ab32160ac80429568 580 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 213 1.1E-18 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 IM45_494 81888ef6988d04bee4f943e5d778824d 481 SUPERFAMILY SSF52540 25 241 1.31E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_494 81888ef6988d04bee4f943e5d778824d 481 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 39 217 5.3E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_494 81888ef6988d04bee4f943e5d778824d 481 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 88 103 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site IM45_494 81888ef6988d04bee4f943e5d778824d 481 SUPERFAMILY SSF50465 342 440 9.83E-29 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal IM45_494 81888ef6988d04bee4f943e5d778824d 481 PRINTS PR00315 GTP-binding elongation factor signature 131 142 8.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_494 81888ef6988d04bee4f943e5d778824d 481 PRINTS PR00315 GTP-binding elongation factor signature 34 47 8.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_494 81888ef6988d04bee4f943e5d778824d 481 PRINTS PR00315 GTP-binding elongation factor signature 115 125 8.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_494 81888ef6988d04bee4f943e5d778824d 481 PRINTS PR00315 GTP-binding elongation factor signature 168 177 8.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_494 81888ef6988d04bee4f943e5d778824d 481 PRINTS PR00315 GTP-binding elongation factor signature 95 103 8.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_494 81888ef6988d04bee4f943e5d778824d 481 SUPERFAMILY SSF50447 248 333 5.82E-23 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_494 81888ef6988d04bee4f943e5d778824d 481 Gene3D G3DSA:2.40.30.10 246 335 5.6E-23 T 12-10-2018 IM45_494 81888ef6988d04bee4f943e5d778824d 481 Gene3D G3DSA:2.40.30.10 338 440 1.2E-27 T 12-10-2018 IM45_494 81888ef6988d04bee4f943e5d778824d 481 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 33 439 2.0E-198 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 IM45_494 81888ef6988d04bee4f943e5d778824d 481 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 24 480 51.166 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 IM45_494 81888ef6988d04bee4f943e5d778824d 481 Pfam PF00009 Elongation factor Tu GTP binding domain 32 232 5.0E-41 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_494 81888ef6988d04bee4f943e5d778824d 481 Gene3D G3DSA:3.40.50.300 12 245 2.7E-67 T 12-10-2018 IM45_1083 699c53a078f4e041ae79a0f57875eaaf 95 Gene3D G3DSA:3.40.1260.10 1 95 1.4E-25 T 12-10-2018 IPR027396 DsrEFH-like IM45_1083 699c53a078f4e041ae79a0f57875eaaf 95 Pfam PF04077 DsrH like protein 8 92 1.6E-22 T 12-10-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 IM45_1083 699c53a078f4e041ae79a0f57875eaaf 95 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 2 95 4.1E-23 T 12-10-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 IM45_1083 699c53a078f4e041ae79a0f57875eaaf 95 SUPERFAMILY SSF75169 1 95 2.02E-25 T 12-10-2018 IPR027396 DsrEFH-like IM45_224 6b90b4bf9f0716fccd3c01ac088e706a 248 Gene3D G3DSA:3.40.1390.30 97 219 3.4E-77 T 12-10-2018 IM45_224 6b90b4bf9f0716fccd3c01ac088e706a 248 Gene3D G3DSA:3.40.1390.30 14 233 3.4E-77 T 12-10-2018 IM45_224 6b90b4bf9f0716fccd3c01ac088e706a 248 SUPERFAMILY SSF102705 1 247 4.71E-76 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily IM45_224 6b90b4bf9f0716fccd3c01ac088e706a 248 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 236 2.9E-51 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 IM45_224 6b90b4bf9f0716fccd3c01ac088e706a 248 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 246 9.5E-67 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 IM45_714 0bac756a534f017f89375a6946c56d84 451 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 27 414 1.9E-105 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 PRINTS PR00447 Natural resistance-associated macrophage protein signature 218 241 6.4E-52 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 PRINTS PR00447 Natural resistance-associated macrophage protein signature 108 134 6.4E-52 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 PRINTS PR00447 Natural resistance-associated macrophage protein signature 390 409 6.4E-52 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 PRINTS PR00447 Natural resistance-associated macrophage protein signature 136 155 6.4E-52 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 PRINTS PR00447 Natural resistance-associated macrophage protein signature 328 347 6.4E-52 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 PRINTS PR00447 Natural resistance-associated macrophage protein signature 356 373 6.4E-52 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 Pfam PF01566 Natural resistance-associated macrophage protein 49 419 4.2E-112 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_714 0bac756a534f017f89375a6946c56d84 451 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 14 446 33.917 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 SUPERFAMILY SSF52540 163 366 7.26E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 SMART SM00962 165 366 7.1E-117 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 94 365 5.1E-107 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 SMART SM00963 71 151 5.5E-20 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 Pfam PF02881 SRP54-type protein, helical bundle domain 85 147 2.7E-9 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 SUPERFAMILY SSF47364 66 144 5.89E-20 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 339 352 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 Pfam PF00448 SRP54-type protein, GTPase domain 165 365 1.9E-75 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 Gene3D G3DSA:1.20.120.140 68 364 1.5E-110 T 12-10-2018 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 Gene3D G3DSA:3.40.50.300 165 354 1.5E-110 T 12-10-2018 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 94 366 61.485 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 IM45_137 e5ff0875ee5457a5bcffbb62fbb20968 369 SMART SM00382 164 356 9.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_568 30fc26ee7aab117a70493a8aab2644be 303 SUPERFAMILY SSF142338 11 295 8.37E-74 T 12-10-2018 IM45_568 30fc26ee7aab117a70493a8aab2644be 303 Gene3D G3DSA:3.40.50.12300 9 295 2.2E-69 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily IM45_568 30fc26ee7aab117a70493a8aab2644be 303 Pfam PF01933 Uncharacterised protein family UPF0052 12 288 3.2E-68 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 IM45_568 30fc26ee7aab117a70493a8aab2644be 303 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 12 257 2.7E-88 T 12-10-2018 IPR010119 Gluconeogenesis factor IM45_568 30fc26ee7aab117a70493a8aab2644be 303 Hamap MF_00973 Gluconeogenesis factor. 8 301 29.104 T 12-10-2018 IPR010119 Gluconeogenesis factor IM45_1149 b5148faf182377e97f759dc8b4809635 497 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 491 5.0E-155 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 IM45_1149 b5148faf182377e97f759dc8b4809635 497 Gene3D G3DSA:3.40.1190.10 105 341 1.2E-76 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1149 b5148faf182377e97f759dc8b4809635 497 Pfam PF01225 Mur ligase family, catalytic domain 22 102 2.5E-11 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 IM45_1149 b5148faf182377e97f759dc8b4809635 497 SUPERFAMILY SSF53244 339 491 6.26E-46 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_1149 b5148faf182377e97f759dc8b4809635 497 Gene3D G3DSA:3.40.1390.10 1 104 1.6E-27 T 12-10-2018 IM45_1149 b5148faf182377e97f759dc8b4809635 497 SUPERFAMILY SSF53623 105 336 4.12E-71 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1149 b5148faf182377e97f759dc8b4809635 497 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 491 32.318 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 IM45_1149 b5148faf182377e97f759dc8b4809635 497 SUPERFAMILY SSF63418 1 103 4.05E-20 T 12-10-2018 IPR035911 MurE/MurF, N-terminal IM45_1149 b5148faf182377e97f759dc8b4809635 497 Gene3D G3DSA:3.90.190.20 342 493 5.9E-53 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_1149 b5148faf182377e97f759dc8b4809635 497 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 424 2.7E-24 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 IM45_1149 b5148faf182377e97f759dc8b4809635 497 Pfam PF08245 Mur ligase middle domain 114 318 2.3E-44 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 IM45_751 ddc7c7d888e1417cada9fb9680858ef9 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 13 198 7.5E-70 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_751 ddc7c7d888e1417cada9fb9680858ef9 201 Pfam PF00573 Ribosomal protein L4/L1 family 13 199 6.5E-60 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 IM45_751 ddc7c7d888e1417cada9fb9680858ef9 201 SUPERFAMILY SSF52166 10 200 2.35E-68 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 IM45_751 ddc7c7d888e1417cada9fb9680858ef9 201 Gene3D G3DSA:3.40.1370.10 4 201 1.2E-63 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 IM45_751 ddc7c7d888e1417cada9fb9680858ef9 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 201 32.297 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_737 3452235a31f2c0a7622f56004bc02cec 72 SUPERFAMILY SSF50249 1 70 2.06E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_737 3452235a31f2c0a7622f56004bc02cec 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.4E-26 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 IM45_737 3452235a31f2c0a7622f56004bc02cec 72 SMART SM00316 4 72 9.4E-8 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_737 3452235a31f2c0a7622f56004bc02cec 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 3.9E-37 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 IM45_737 3452235a31f2c0a7622f56004bc02cec 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.051 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 IM45_737 3452235a31f2c0a7622f56004bc02cec 72 Gene3D G3DSA:2.40.50.140 1 72 8.0E-34 T 12-10-2018 IM45_1157 e323218545949c39dff0c03722386e63 313 SUPERFAMILY SSF53335 5 313 2.18E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_1157 e323218545949c39dff0c03722386e63 313 SUPERFAMILY SSF81799 112 211 3.4E-33 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 IM45_1157 e323218545949c39dff0c03722386e63 313 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 313 36.655 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 IM45_1157 e323218545949c39dff0c03722386e63 313 Gene3D G3DSA:3.40.50.150 8 312 4.1E-101 T 12-10-2018 IM45_1157 e323218545949c39dff0c03722386e63 313 Gene3D G3DSA:1.10.150.170 110 212 4.1E-101 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 IM45_1157 e323218545949c39dff0c03722386e63 313 Pfam PF01795 MraW methylase family 3 312 2.4E-107 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 IM45_1157 e323218545949c39dff0c03722386e63 313 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 312 9.7E-113 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 IM45_1157 e323218545949c39dff0c03722386e63 313 PIRSF PIRSF004486 1 313 4.3E-99 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 179 1.5E-33 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Gene3D G3DSA:3.40.120.10 13 219 1.3E-71 T 12-10-2018 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 SUPERFAMILY SSF53738 210 318 1.13E-9 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 321 441 4.1E-27 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Gene3D G3DSA:3.40.120.10 320 443 3.6E-31 T 12-10-2018 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 SUPERFAMILY SSF53738 306 448 2.16E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 2.3E-5 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 140 154 2.3E-5 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 229 248 2.3E-5 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Gene3D G3DSA:3.30.310.50 444 545 2.0E-29 T 12-10-2018 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 SUPERFAMILY SSF53738 27 235 4.94E-49 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Gene3D G3DSA:3.40.120.10 222 319 2.0E-42 T 12-10-2018 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 4 544 1.1E-272 T 12-10-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-6981|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7900|MetaCyc: PWY-7902 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 SUPERFAMILY SSF55957 434 545 3.4E-17 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 318 4.5E-18 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_220 547de0a7f5fbffa1352b95585eeb2118 545 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 486 540 2.2E-7 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 IM45_205 d8ffc38cd914a5020527a8fd9eb75b8e 219 Gene3D G3DSA:3.30.420.10 9 213 7.0E-56 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 IM45_205 d8ffc38cd914a5020527a8fd9eb75b8e 219 Pfam PF00929 Exonuclease 20 194 8.2E-36 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III IM45_205 d8ffc38cd914a5020527a8fd9eb75b8e 219 SMART SM00479 18 203 1.1E-36 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III IM45_205 d8ffc38cd914a5020527a8fd9eb75b8e 219 Hamap MF_00157 Ribonuclease T [rnt]. 1 219 112.323 T 12-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 IM45_205 d8ffc38cd914a5020527a8fd9eb75b8e 219 TIGRFAM TIGR01298 RNaseT: ribonuclease T 11 208 5.5E-106 T 12-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 IM45_205 d8ffc38cd914a5020527a8fd9eb75b8e 219 SUPERFAMILY SSF53098 9 208 9.76E-57 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily IM45_749 42027f0b02fd6f6e82a86783b3a3e7b7 211 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 204 3.6E-87 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_749 42027f0b02fd6f6e82a86783b3a3e7b7 211 Pfam PF00297 Ribosomal protein L3 105 182 1.6E-14 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_749 42027f0b02fd6f6e82a86783b3a3e7b7 211 Gene3D G3DSA:2.40.30.10 128 210 1.1E-18 T 12-10-2018 IM45_749 42027f0b02fd6f6e82a86783b3a3e7b7 211 Gene3D G3DSA:2.40.50.620 32 96 3.5E-14 T 12-10-2018 IM45_749 42027f0b02fd6f6e82a86783b3a3e7b7 211 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site IM45_749 42027f0b02fd6f6e82a86783b3a3e7b7 211 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 207 38.594 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_749 42027f0b02fd6f6e82a86783b3a3e7b7 211 SUPERFAMILY SSF50447 3 208 2.65E-75 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_461 dced388a3d7518c0d49510778cc1a4c9 248 SUPERFAMILY SSF75217 1 245 1.18E-98 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases IM45_461 dced388a3d7518c0d49510778cc1a4c9 248 Gene3D G3DSA:1.10.1270.20 161 248 3.4E-34 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 IM45_461 dced388a3d7518c0d49510778cc1a4c9 248 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 248 112.115 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 IM45_461 dced388a3d7518c0d49510778cc1a4c9 248 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 3.6E-66 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 IM45_461 dced388a3d7518c0d49510778cc1a4c9 248 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 5.4E-105 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 IM45_461 dced388a3d7518c0d49510778cc1a4c9 248 Gene3D G3DSA:3.40.1280.10 1 160 4.8E-64 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal IM45_461 dced388a3d7518c0d49510778cc1a4c9 248 PIRSF PIRSF000386 1 248 1.0E-99 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 IM45_801 60b73c4313bfadca22fda87122784f36 125 Pfam PF01196 Ribosomal protein L17 20 116 1.2E-32 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_801 60b73c4313bfadca22fda87122784f36 125 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 2.5E-44 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_801 60b73c4313bfadca22fda87122784f36 125 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_801 60b73c4313bfadca22fda87122784f36 125 Gene3D G3DSA:3.90.1030.10 1 117 2.6E-44 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_801 60b73c4313bfadca22fda87122784f36 125 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.034 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_801 60b73c4313bfadca22fda87122784f36 125 SUPERFAMILY SSF64263 1 118 2.22E-47 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_401 8eb627046700982931d6224f55f16b31 163 Gene3D G3DSA:3.40.50.620 1 161 4.0E-52 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_401 8eb627046700982931d6224f55f16b31 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 7 159 4.1E-59 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 IM45_401 8eb627046700982931d6224f55f16b31 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 52 76 3.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 IM45_401 8eb627046700982931d6224f55f16b31 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 88 104 3.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 IM45_401 8eb627046700982931d6224f55f16b31 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 23 44 3.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 IM45_401 8eb627046700982931d6224f55f16b31 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 5 23 3.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 IM45_401 8eb627046700982931d6224f55f16b31 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 115 137 3.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 IM45_401 8eb627046700982931d6224f55f16b31 163 Pfam PF01467 Cytidylyltransferase-like 8 136 5.6E-21 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 IM45_401 8eb627046700982931d6224f55f16b31 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 7 65 9.1E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 IM45_401 8eb627046700982931d6224f55f16b31 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 5 161 34.462 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 IM45_401 8eb627046700982931d6224f55f16b31 163 SUPERFAMILY SSF52374 5 156 7.51E-42 T 12-10-2018 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Gene3D G3DSA:3.30.1480.10 1 129 1.8E-44 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 441 489 1.2E-14 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 365 414 2.3E-17 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 SUPERFAMILY SSF54814 201 278 2.03E-29 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 SMART SM00316 133 200 6.9E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Gene3D G3DSA:1.10.150.20 352 421 4.7E-24 T 12-10-2018 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Gene3D G3DSA:2.40.50.140 135 198 4.3E-18 T 12-10-2018 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Pfam PF00575 S1 RNA binding domain 134 193 2.6E-4 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Pfam PF14520 Helix-hairpin-helix domain 432 486 4.5E-8 T 12-10-2018 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Pfam PF13184 NusA-like KH domain 230 297 4.4E-27 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Gene3D G3DSA:1.10.150.20 431 490 1.4E-21 T 12-10-2018 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 SUPERFAMILY SSF47794 428 492 1.1E-15 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 SUPERFAMILY SSF50249 132 199 5.4E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 SUPERFAMILY SSF54814 280 341 1.22E-14 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Gene3D G3DSA:3.30.300.20 199 277 6.8E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 410 28.773 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 341 1.3E-126 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 SUPERFAMILY SSF69705 1 126 2.35E-39 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Pfam PF08529 NusA N-terminal domain 4 123 7.2E-36 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 SUPERFAMILY SSF47794 356 414 3.77E-14 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 IM45_1385 9c2aadce549933c383b6cdaf0a6a552a 495 Gene3D G3DSA:3.30.300.20 278 343 1.3E-21 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta IM45_741 857582f27cbabe8e479c7cde525a8213 248 SUPERFAMILY SSF53850 1 245 1.72E-64 T 12-10-2018 IM45_741 857582f27cbabe8e479c7cde525a8213 248 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 23 244 2.0E-61 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF IM45_741 857582f27cbabe8e479c7cde525a8213 248 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 45 58 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site IM45_741 857582f27cbabe8e479c7cde525a8213 248 Gene3D G3DSA:3.40.190.10 109 203 5.2E-70 T 12-10-2018 IM45_741 857582f27cbabe8e479c7cde525a8213 248 SMART SM00079 22 245 1.9E-4 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 IM45_741 857582f27cbabe8e479c7cde525a8213 248 Gene3D G3DSA:3.40.190.10 25 242 5.2E-70 T 12-10-2018 IM45_741 857582f27cbabe8e479c7cde525a8213 248 SMART SM00062 22 246 3.1E-63 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF IM45_367 4972a6f4aa44d037fbef1f1ff7800504 305 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 25 292 2.4E-99 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 IM45_367 4972a6f4aa44d037fbef1f1ff7800504 305 Gene3D G3DSA:3.20.20.220 1 303 1.9E-109 T 12-10-2018 IM45_367 4972a6f4aa44d037fbef1f1ff7800504 305 Pfam PF02219 Methylenetetrahydrofolate reductase 17 293 5.4E-102 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 IM45_367 4972a6f4aa44d037fbef1f1ff7800504 305 SUPERFAMILY SSF51730 22 296 1.47E-91 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 31.966 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.4E-35 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.4E-35 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.4E-35 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.4E-35 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.4E-35 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 Pfam PF00334 Nucleoside diphosphate kinase 4 137 4.5E-51 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 SUPERFAMILY SSF54919 1 138 6.81E-54 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 Gene3D G3DSA:3.30.70.141 2 142 1.3E-51 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_013 d16610396a2a78b9d74e75a4c4b4899f 143 SMART SM00562 3 140 3.2E-70 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 Pfam PF01966 HD domain 228 300 1.2E-7 T 12-10-2018 IPR006674 HD domain IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 SUPERFAMILY SSF81891 122 401 2.22E-55 T 12-10-2018 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 Gene3D G3DSA:1.10.3090.10 123 406 2.8E-41 T 12-10-2018 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 Pfam PF01743 Poly A polymerase head domain 4 123 2.6E-14 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 SUPERFAMILY SSF81301 2 120 4.8E-25 T 12-10-2018 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 PIRSF PIRSF000813 1 407 1.7E-179 T 12-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 Hamap MF_01262 CCA-adding enzyme [cca]. 1 400 43.05 T 12-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 406 47.636 T 12-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 Gene3D G3DSA:3.30.460.10 1 122 3.8E-25 T 12-10-2018 IM45_1359 28b5fa42e391565dc40cef0005ce5cdd 408 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 150 210 3.8E-14 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 78 1.6E-30 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 41 62 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 11 76 14.099 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 PRINTS PR00124 ATP synthase C subunit signature 13 32 1.5E-7 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 PRINTS PR00124 ATP synthase C subunit signature 51 76 1.5E-7 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 PRINTS PR00124 ATP synthase C subunit signature 34 49 1.5E-7 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 Pfam PF00137 ATP synthase subunit C 12 71 1.1E-8 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 Gene3D G3DSA:1.20.20.10 1 80 6.0E-31 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_339 e4ea3a1427e278ea41c79f96334f8c64 80 SUPERFAMILY SSF81333 6 78 2.48E-17 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily IM45_890 6e54fecef0c424b27cc690907e8b729a 467 SUPERFAMILY SSF48179 176 466 2.24E-128 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 PIRSF PIRSF000109 1 467 1.6E-232 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 173 3.5E-49 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 466 9.9E-130 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 467 4.4E-221 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 Gene3D G3DSA:3.40.50.720 1 179 6.7E-54 T 12-10-2018 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 Gene3D G3DSA:1.10.1040.10 180 434 7.9E-106 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 SUPERFAMILY SSF51735 5 176 5.57E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_890 6e54fecef0c424b27cc690907e8b729a 467 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 1.8E-86 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.8E-86 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 248 275 1.8E-86 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.8E-86 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 356 378 1.8E-86 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.8E-86 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 SMART SM01350 178 467 1.8E-208 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 IM45_890 6e54fecef0c424b27cc690907e8b729a 467 Gene3D G3DSA:1.20.5.320 435 467 2.1E-21 T 12-10-2018 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Pfam PF04545 Sigma-70, region 4 547 600 1.0E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Pfam PF03979 Sigma-70 factor, region 1.1 4 78 8.6E-30 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Gene3D G3DSA:1.10.601.10 113 448 2.0E-137 T 12-10-2018 IM45_1347 c54645ee1550eac0a650374be5598af8 613 PRINTS PR00046 Major sigma-70 factor signature 427 435 6.3E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 PRINTS PR00046 Major sigma-70 factor signature 572 587 6.3E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 PRINTS PR00046 Major sigma-70 factor signature 551 563 6.3E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 PRINTS PR00046 Major sigma-70 factor signature 587 598 6.3E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 PRINTS PR00046 Major sigma-70 factor signature 403 416 6.3E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 375 611 3.6E-120 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Pfam PF04542 Sigma-70 region 2 379 448 1.7E-21 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 572 598 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 612 46.143 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Gene3D G3DSA:1.10.220.120 1 64 7.1E-30 T 12-10-2018 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Pfam PF00140 Sigma-70 factor, region 1.2 98 128 1.8E-12 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 IM45_1347 c54645ee1550eac0a650374be5598af8 613 SUPERFAMILY SSF88946 115 446 3.66E-96 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 SUPERFAMILY SSF88659 509 611 2.49E-25 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like IM45_1347 c54645ee1550eac0a650374be5598af8 613 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 403 416 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Pfam PF04539 Sigma-70 region 3 458 533 8.3E-29 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 IM45_1347 c54645ee1550eac0a650374be5598af8 613 Gene3D G3DSA:1.10.10.10 529 613 2.9E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_1347 c54645ee1550eac0a650374be5598af8 613 Pfam PF04546 Sigma-70, non-essential region 139 348 1.6E-67 T 12-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 IM45_1347 c54645ee1550eac0a650374be5598af8 613 SUPERFAMILY SSF88659 452 525 1.31E-20 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like IM45_1347 c54645ee1550eac0a650374be5598af8 613 Gene3D G3DSA:1.10.10.10 452 528 9.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_1347 c54645ee1550eac0a650374be5598af8 613 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 375 600 3.0E-38 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 12 309 18.418 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 252 309 1.3E-15 T 12-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 Gene3D G3DSA:2.30.130.10 250 313 1.9E-14 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 Gene3D G3DSA:3.30.2350.10 4 249 1.4E-86 T 12-10-2018 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 SUPERFAMILY SSF55120 12 247 2.19E-79 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 SUPERFAMILY SSF88697 251 309 1.79E-10 T 12-10-2018 IPR015947 PUA-like superfamily IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 182 248 1.5E-20 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 12 220 6.4E-82 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_1379 d11bf371edeed51c54298c6c6de6e889 314 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 34 181 1.4E-56 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 IM45_1265 d172143f5a91e80d7cc1b09cec3e616b 126 Gene3D G3DSA:3.30.70.60 1 92 1.1E-31 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 IM45_1265 d172143f5a91e80d7cc1b09cec3e616b 126 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.5E-36 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1265 d172143f5a91e80d7cc1b09cec3e616b 126 SUPERFAMILY SSF54995 1 103 3.27E-36 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1265 d172143f5a91e80d7cc1b09cec3e616b 126 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.335 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 IM45_1265 d172143f5a91e80d7cc1b09cec3e616b 126 Pfam PF01250 Ribosomal protein S6 3 91 1.3E-27 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1133 6c15401ad8a81c6487104c4125023771 387 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 334 7.7E-140 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 IM45_1133 6c15401ad8a81c6487104c4125023771 387 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 377 37.846 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 IM45_1133 6c15401ad8a81c6487104c4125023771 387 SUPERFAMILY SSF55307 204 320 2.29E-41 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 IM45_1133 6c15401ad8a81c6487104c4125023771 387 PRINTS PR00423 Cell division protein FtsZ signature 126 147 2.9E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 PRINTS PR00423 Cell division protein FtsZ signature 212 233 2.9E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 PRINTS PR00423 Cell division protein FtsZ signature 98 118 2.9E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 PRINTS PR00423 Cell division protein FtsZ signature 189 211 2.9E-52 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 Gene3D G3DSA:3.40.50.1440 10 317 1.4E-115 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 SMART SM00864 13 205 7.5E-112 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 Pfam PF12327 FtsZ family, C-terminal domain 222 316 9.9E-37 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal IM45_1133 6c15401ad8a81c6487104c4125023771 387 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 2.3E-41 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 IM45_1133 6c15401ad8a81c6487104c4125023771 387 SMART SM00865 207 325 1.7E-53 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 IM45_1133 6c15401ad8a81c6487104c4125023771 387 SUPERFAMILY SSF52490 13 208 2.75E-70 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 SUPERFAMILY SSF56059 79 274 2.75E-50 T 12-10-2018 IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 Gene3D G3DSA:3.30.1490.20 94 151 6.1E-18 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 SUPERFAMILY SSF52440 2 76 9.93E-16 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 Pfam PF02222 ATP-grasp domain 88 254 9.2E-49 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 4 327 3.1E-102 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 SUPERFAMILY SSF51246 278 352 4.24E-19 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 Gene3D G3DSA:3.40.50.20 1 70 1.3E-29 T 12-10-2018 IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 Gene3D G3DSA:3.30.470.20 152 355 7.0E-72 T 12-10-2018 IM45_282 cc35f36896f15f9cdabaa0d139a5180b 356 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 325 31.833 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 175 298 8.4E-32 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 311 76.567 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 SUPERFAMILY SSF56176 3 167 1.27E-39 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 Gene3D G3DSA:3.90.78.10 189 311 7.5E-42 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 Gene3D G3DSA:3.30.465.10 39 188 6.7E-55 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 SUPERFAMILY SSF56194 172 305 1.7E-47 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 Gene3D G3DSA:3.30.43.10 1 38 8.3E-9 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 Pfam PF01565 FAD binding domain 3 119 3.0E-20 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 IM45_1109 1fbf1c769ca439ee471b684078017f81 311 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 3 299 2.1E-90 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1223 ef836654385e983c026fdc90fe802b66 327 SMART SM00904 183 310 1.6E-54 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 IM45_1223 ef836654385e983c026fdc90fe802b66 327 Gene3D G3DSA:3.40.50.620 1 186 2.2E-54 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_1223 ef836654385e983c026fdc90fe802b66 327 Pfam PF01687 Riboflavin kinase 184 309 7.6E-34 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 IM45_1223 ef836654385e983c026fdc90fe802b66 327 SUPERFAMILY SSF82114 175 310 1.57E-38 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 IM45_1223 ef836654385e983c026fdc90fe802b66 327 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 310 1.8E-96 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 IM45_1223 ef836654385e983c026fdc90fe802b66 327 Gene3D G3DSA:2.40.30.30 188 315 2.3E-35 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 IM45_1223 ef836654385e983c026fdc90fe802b66 327 Pfam PF06574 FAD synthetase 12 167 1.6E-51 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 IM45_1223 ef836654385e983c026fdc90fe802b66 327 PIRSF PIRSF004491 1 317 4.8E-95 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 IM45_1223 ef836654385e983c026fdc90fe802b66 327 SUPERFAMILY SSF52374 15 175 1.52E-34 T 12-10-2018 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 Gene3D G3DSA:3.30.230.40 255 355 2.0E-35 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 3 162 7.3E-73 T 12-10-2018 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 196 337 4.7E-64 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 SUPERFAMILY SSF54211 167 250 3.04E-29 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 149 2.1E-21 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 226 239 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 SUPERFAMILY SSF54211 252 342 2.53E-32 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 Gene3D G3DSA:3.30.230.40 164 254 2.9E-33 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 145 3.7E-39 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 2 355 49.067 T 12-10-2018 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 SUPERFAMILY SSF56784 3 156 1.93E-32 T 12-10-2018 IPR036412 HAD-like superfamily IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 Gene3D G3DSA:3.40.50.1000 1 163 8.4E-40 T 12-10-2018 IPR023214 HAD superfamily IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 167 355 36.113 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 319 331 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 IM45_899 8fbded85bd3c5b3fc8d3fd6a4ef0d274 355 Pfam PF13242 HAD-hyrolase-like 120 146 1.3E-4 T 12-10-2018 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 SUPERFAMILY SSF74731 3 116 9.81E-49 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 Pfam PF00453 Ribosomal protein L20 3 109 6.7E-47 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 Gene3D G3DSA:1.10.1900.20 56 118 7.0E-28 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.9E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.9E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.9E-41 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.993 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 Gene3D G3DSA:1.10.720.90 2 55 1.6E-24 T 12-10-2018 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 7.4E-50 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1037 a05d684ad14726d9cf2a44254ff26efd 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 2.0E-18 T 12-10-2018 IM45_297 f1168f18352cc7c782abf3b1c2830e8a 238 Gene3D G3DSA:1.20.120.1600 24 110 1.1E-56 T 12-10-2018 IM45_297 f1168f18352cc7c782abf3b1c2830e8a 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 207 1.7E-9 T 12-10-2018 IM45_297 f1168f18352cc7c782abf3b1c2830e8a 238 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 120 207 5.5E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 IM45_297 f1168f18352cc7c782abf3b1c2830e8a 238 SUPERFAMILY SSF56784 10 237 1.28E-34 T 12-10-2018 IPR036412 HAD-like superfamily IM45_297 f1168f18352cc7c782abf3b1c2830e8a 238 Gene3D G3DSA:3.40.50.1000 11 231 1.1E-56 T 12-10-2018 IPR023214 HAD superfamily IM45_297 f1168f18352cc7c782abf3b1c2830e8a 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 128 201 1.3E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 IM45_1389 6dec5f390f986ca40cf1756aa756ba8f 83 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 44 5.6E-11 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 IM45_1389 6dec5f390f986ca40cf1756aa756ba8f 83 PRINTS PR01651 Protein-export SecG membrane protein signature 25 47 1.3E-16 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 IM45_1389 6dec5f390f986ca40cf1756aa756ba8f 83 PRINTS PR01651 Protein-export SecG membrane protein signature 9 25 1.3E-16 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 IM45_1389 6dec5f390f986ca40cf1756aa756ba8f 83 Pfam PF03840 Preprotein translocase SecG subunit 4 43 2.0E-8 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 IM45_1391 329930a05bb20a1cef4fc4b627478fc5 288 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 24 278 5.0E-97 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 IM45_1391 329930a05bb20a1cef4fc4b627478fc5 288 SUPERFAMILY SSF51717 11 279 2.62E-99 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 IM45_1391 329930a05bb20a1cef4fc4b627478fc5 288 Pfam PF00809 Pterin binding enzyme 25 264 1.0E-81 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 IM45_1391 329930a05bb20a1cef4fc4b627478fc5 288 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 58 71 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 IM45_1391 329930a05bb20a1cef4fc4b627478fc5 288 Gene3D G3DSA:3.20.20.20 8 286 3.5E-106 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 IM45_1391 329930a05bb20a1cef4fc4b627478fc5 288 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 24 39 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 Pfam PF00312 Ribosomal protein S15 8 88 2.5E-32 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 6.5E-35 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 Gene3D G3DSA:1.10.287.10 2 89 1.2E-31 T 12-10-2018 IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 SMART SM01387 8 88 2.7E-43 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 9.0E-31 T 12-10-2018 IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 SUPERFAMILY SSF47060 3 89 2.85E-30 T 12-10-2018 IPR009068 S15/NS1, RNA-binding IM45_1377 5c6a42ce16cb18a30038e14971d75602 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 20.196 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_942 a28b31151fe4cb6cc9573862cc174252 371 Gene3D G3DSA:2.30.30.280 214 282 3.7E-27 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 IM45_942 a28b31151fe4cb6cc9573862cc174252 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 7 361 2.8E-144 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 IM45_942 a28b31151fe4cb6cc9573862cc174252 371 Pfam PF03054 tRNA methyl transferase 7 361 1.1E-135 T 12-10-2018 IM45_942 a28b31151fe4cb6cc9573862cc174252 371 Gene3D G3DSA:3.40.50.620 1 213 8.3E-92 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_942 a28b31151fe4cb6cc9573862cc174252 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 362 38.049 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 IM45_942 a28b31151fe4cb6cc9573862cc174252 371 SUPERFAMILY SSF52402 5 296 3.75E-53 T 12-10-2018 IM45_942 a28b31151fe4cb6cc9573862cc174252 371 Gene3D G3DSA:2.40.30.10 283 367 1.0E-28 T 12-10-2018 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 Pfam PF00216 Bacterial DNA-binding protein 3 89 4.5E-30 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 4.1E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 4.1E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 4.1E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 SMART SM00411 3 92 3.2E-41 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 96 27.028 T 12-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 SUPERFAMILY SSF47729 3 92 1.62E-30 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 92 4.0E-45 T 12-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 IM45_1031 f68eb4c57a901bf6edc61d4e40201124 96 Gene3D G3DSA:4.10.520.10 1 95 9.6E-36 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 427 552 6.4E-4 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 PRINTS PR00397 Sirohaem Fe-binding site signature 473 491 6.2E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 PRINTS PR00397 Sirohaem Fe-binding site signature 425 443 6.2E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 473 489 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 SUPERFAMILY SSF55124 10 140 8.67E-25 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 168 326 1.8E-40 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 349 410 6.4E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 76 133 2.3E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 14 554 4.5E-278 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 Gene3D G3DSA:3.30.413.10 421 563 3.3E-34 T 12-10-2018 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 SUPERFAMILY SSF56014 144 339 2.49E-53 T 12-10-2018 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 SUPERFAMILY SSF55124 341 419 4.42E-22 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 Gene3D G3DSA:3.90.480.10 332 419 5.3E-31 T 12-10-2018 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 2 566 57.524 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 IM45_503 9533315d5b46c89a8f4472b0d404f67d 566 SUPERFAMILY SSF56014 426 555 6.94E-31 T 12-10-2018 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.8E-35 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 SUPERFAMILY SSF56059 83 347 6.01E-63 T 12-10-2018 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 SUPERFAMILY SSF51246 331 444 3.87E-41 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 Gene3D G3DSA:3.30.470.20 86 433 1.5E-149 T 12-10-2018 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 SMART SM00878 336 441 2.9E-58 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 9.3E-44 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 Gene3D G3DSA:3.30.1490.20 131 203 1.5E-149 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 2.2E-79 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 Gene3D G3DSA:3.40.50.20 1 85 7.4E-34 T 12-10-2018 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 7.1E-237 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 IM45_123 bd89d6ad7c91ace0f712e18447c079cd 449 SUPERFAMILY SSF52440 1 113 4.75E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily IM45_821 371f7ab2548e575cc610f09548dc6b61 288 Pfam PF01039 Carboxyl transferase domain 104 240 2.2E-13 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 281 36.362 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 Gene3D G3DSA:3.90.226.10 25 284 3.4E-80 T 12-10-2018 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 SUPERFAMILY SSF52096 25 279 4.98E-82 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily IM45_821 371f7ab2548e575cc610f09548dc6b61 288 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 283 1.1E-141 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 3.5E-36 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 3.5E-36 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 3.5E-36 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 3.5E-36 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_821 371f7ab2548e575cc610f09548dc6b61 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 3.5E-36 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 871 884 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 787 798 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 726 739 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 673 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 841 857 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 696 719 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 750 775 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 809 820 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 PRINTS PR00868 DNA-polymerase family A (pol I) signature 674 689 2.5E-73 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 TIGRFAM TIGR00593 pola: DNA polymerase I 6 923 1.9E-269 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 Pfam PF01612 3'-5' exonuclease 324 512 8.2E-29 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 IM45_270 d804904fd804eb0126cc72452bc36582 924 ProSitePatterns PS00447 DNA polymerase family A signature. 750 769 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 Gene3D G3DSA:3.30.420.10 321 538 7.3E-60 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 IM45_270 d804904fd804eb0126cc72452bc36582 924 SUPERFAMILY SSF53098 327 514 1.61E-44 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily IM45_270 d804904fd804eb0126cc72452bc36582 924 Gene3D G3DSA:1.10.150.20 705 848 7.0E-110 T 12-10-2018 IM45_270 d804904fd804eb0126cc72452bc36582 924 SMART SM00279 170 205 5.1E-12 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 IM45_270 d804904fd804eb0126cc72452bc36582 924 SMART SM00475 4 266 1.4E-112 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 IM45_270 d804904fd804eb0126cc72452bc36582 924 SMART SM00482 682 888 1.4E-109 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 Gene3D G3DSA:3.30.70.370 660 920 7.0E-110 T 12-10-2018 IM45_270 d804904fd804eb0126cc72452bc36582 924 SUPERFAMILY SSF88723 4 167 4.17E-49 T 12-10-2018 IPR029060 PIN-like domain superfamily IM45_270 d804904fd804eb0126cc72452bc36582 924 SMART SM00474 324 513 9.7E-30 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 IM45_270 d804904fd804eb0126cc72452bc36582 924 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 168 269 1.4E-28 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 IM45_270 d804904fd804eb0126cc72452bc36582 924 SUPERFAMILY SSF56672 518 923 1.01E-149 T 12-10-2018 IM45_270 d804904fd804eb0126cc72452bc36582 924 Gene3D G3DSA:1.10.150.20 171 251 4.0E-87 T 12-10-2018 IM45_270 d804904fd804eb0126cc72452bc36582 924 Gene3D G3DSA:3.40.50.1010 6 282 4.0E-87 T 12-10-2018 IM45_270 d804904fd804eb0126cc72452bc36582 924 Gene3D G3DSA:1.20.1060.10 539 654 1.5E-35 T 12-10-2018 IM45_270 d804904fd804eb0126cc72452bc36582 924 SUPERFAMILY SSF47807 168 286 5.23E-28 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily IM45_270 d804904fd804eb0126cc72452bc36582 924 Pfam PF00476 DNA polymerase family A 547 921 3.2E-145 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_270 d804904fd804eb0126cc72452bc36582 924 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 167 1.0E-47 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 IM45_589 4581efc519d738d225950470b2248093 63 Pfam PF03966 Trm112p-like protein 2 39 5.0E-7 T 12-10-2018 IPR005651 Trm112-like IM45_589 4581efc519d738d225950470b2248093 63 SUPERFAMILY SSF158997 1 54 6.28E-18 T 12-10-2018 IM45_589 4581efc519d738d225950470b2248093 63 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 24.437 T 12-10-2018 IPR038053 Uncharacterised protein family UPF0434 IM45_589 4581efc519d738d225950470b2248093 63 Gene3D G3DSA:2.20.25.10 8 62 4.3E-21 T 12-10-2018 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Pfam PF00580 UvrD/REP helicase N-terminal domain 1 415 1.2E-53 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Pfam PF13361 UvrD-like helicase C-terminal domain 712 788 9.0E-12 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 SUPERFAMILY SSF52540 1 800 2.98E-98 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 1 1160 20.862 T 12-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Gene3D G3DSA:3.90.320.10 875 1165 1.8E-97 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 SUPERFAMILY SSF52980 886 1161 1.23E-80 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Gene3D G3DSA:1.10.486.10 563 708 4.1E-151 T 12-10-2018 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Gene3D G3DSA:3.40.50.300 425 826 4.1E-151 T 12-10-2018 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Gene3D G3DSA:1.10.3170.10 136 329 5.4E-140 T 12-10-2018 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 1 1159 0.0 T 12-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 IM45_1207 9c4268f1cc9bbfedf350962987b843c1 1165 Gene3D G3DSA:3.40.50.300 1 415 5.4E-140 T 12-10-2018 IM45_1019 abbcee8b8ca8d84db442ef73533e9f4c 138 Pfam PF02657 Fe-S metabolism associated domain 12 132 3.9E-42 T 12-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like IM45_1019 abbcee8b8ca8d84db442ef73533e9f4c 138 SUPERFAMILY SSF82649 4 135 3.92E-44 T 12-10-2018 IM45_1019 abbcee8b8ca8d84db442ef73533e9f4c 138 Gene3D G3DSA:3.90.1010.10 2 138 1.8E-48 T 12-10-2018 IM45_381 5d8cf55e8bcdf57469778b1aed552573 263 Gene3D G3DSA:3.20.20.70 1 255 7.0E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_381 5d8cf55e8bcdf57469778b1aed552573 263 Pfam PF00121 Triosephosphate isomerase 5 246 2.0E-88 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_381 5d8cf55e8bcdf57469778b1aed552573 263 SUPERFAMILY SSF51351 1 251 1.44E-85 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_381 5d8cf55e8bcdf57469778b1aed552573 263 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 57.183 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_381 5d8cf55e8bcdf57469778b1aed552573 263 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.2E-81 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 Gene3D G3DSA:3.40.190.10 93 182 6.0E-68 T 12-10-2018 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 SUPERFAMILY SSF54913 216 288 1.56E-21 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 146 167 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 289 32.706 T 12-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 Pfam PF01634 ATP phosphoribosyltransferase 44 209 1.3E-44 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 187 3.9E-52 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 Gene3D G3DSA:3.40.190.10 1 211 6.0E-68 T 12-10-2018 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 Pfam PF08029 HisG, C-terminal domain 213 286 4.4E-24 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 Gene3D G3DSA:3.30.70.120 216 289 8.4E-34 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 195 288 5.4E-31 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 IM45_906 d3a1e150dfbe8307e846e6ebb5ee5d61 289 SUPERFAMILY SSF53850 1 214 3.12E-63 T 12-10-2018 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 Gene3D G3DSA:3.40.50.300 20 183 1.3E-40 T 12-10-2018 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 333 4.0E-34 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 336 172.827 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 SMART SM00382 53 180 8.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_716 584b6fc588a4410f4f73200c460d2c90 336 SUPERFAMILY SSF46785 259 329 7.26E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_716 584b6fc588a4410f4f73200c460d2c90 336 Gene3D G3DSA:1.10.8.60 184 257 3.8E-30 T 12-10-2018 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 255 328 2.3E-33 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 Gene3D G3DSA:1.10.10.10 259 335 4.5E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_716 584b6fc588a4410f4f73200c460d2c90 336 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 12 237 2.3E-115 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 1.8E-146 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 IM45_716 584b6fc588a4410f4f73200c460d2c90 336 SUPERFAMILY SSF52540 22 254 4.09E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 Gene3D G3DSA:2.40.50.140 1 114 6.6E-49 T 12-10-2018 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 SUPERFAMILY SSF50104 127 269 7.22E-59 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 1.0E-128 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 249 2.5E-55 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 Gene3D G3DSA:4.10.950.10 196 273 5.2E-36 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 SUPERFAMILY SSF50249 3 125 5.48E-47 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.5E-33 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 45.945 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 SMART SM01383 42 118 5.2E-46 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 PIRSF PIRSF002158 12 273 1.4E-100 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 Gene3D G3DSA:2.30.30.30 115 195 3.4E-33 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 IM45_755 61a45fce3e235a3dda9e6b867f5dc996 273 SMART SM01382 124 251 4.3E-89 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 327 348 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Gene3D G3DSA:3.10.50.40 176 278 1.5E-63 T 12-10-2018 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Gene3D G3DSA:1.10.4030.30 388 432 1.9E-5 T 12-10-2018 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 SUPERFAMILY SSF109998 29 201 8.37E-32 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Pfam PF13616 PPIC-type PPIASE domain 289 389 4.9E-21 T 12-10-2018 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Pfam PF09312 SurA N-terminal domain 29 146 1.1E-27 T 12-10-2018 IPR015391 SurA N-terminal IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Hamap MF_01183 Chaperone SurA [surA]. 11 432 28.511 T 12-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 SUPERFAMILY SSF54534 289 390 3.6E-26 T 12-10-2018 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 SUPERFAMILY SSF54534 176 279 8.5E-18 T 12-10-2018 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Gene3D G3DSA:1.10.4030.30 30 282 1.5E-63 T 12-10-2018 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Pfam PF00639 PPIC-type PPIASE domain 182 276 4.6E-15 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 IM45_1245 eaa7bbbeb353d9fcd05beec0994d4b3e 435 Gene3D G3DSA:3.10.50.40 286 387 2.1E-28 T 12-10-2018 IM45_073 96ea85224a77da64b40ec1f77d0b9682 417 Gene3D G3DSA:3.65.10.10 7 413 3.1E-166 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 IM45_073 96ea85224a77da64b40ec1f77d0b9682 417 Gene3D G3DSA:3.65.10.10 21 228 3.1E-166 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 IM45_073 96ea85224a77da64b40ec1f77d0b9682 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 3.5E-119 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 IM45_073 96ea85224a77da64b40ec1f77d0b9682 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 43.265 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_073 96ea85224a77da64b40ec1f77d0b9682 417 SUPERFAMILY SSF55205 1 416 6.21E-140 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 IM45_073 96ea85224a77da64b40ec1f77d0b9682 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 9.5E-178 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 498 39.626 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 PRINTS PR00481 Cytosol aminopeptidase signature 265 282 5.2E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 PRINTS PR00481 Cytosol aminopeptidase signature 346 366 5.2E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 PRINTS PR00481 Cytosol aminopeptidase signature 324 345 5.2E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 PRINTS PR00481 Cytosol aminopeptidase signature 374 389 5.2E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 PRINTS PR00481 Cytosol aminopeptidase signature 287 308 5.2E-50 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 SUPERFAMILY SSF53187 180 496 4.71E-121 T 12-10-2018 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 SUPERFAMILY SSF52949 1 184 5.06E-51 T 12-10-2018 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 Gene3D G3DSA:3.40.630.10 181 498 2.6E-135 T 12-10-2018 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 350 357 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 Gene3D G3DSA:3.40.220.10 1 159 7.4E-56 T 12-10-2018 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 2.9E-32 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 IM45_656 a1a41c896b450404a0d61555a4c03e4e 507 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 489 1.0E-118 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 Gene3D G3DSA:3.30.930.10 109 465 8.1E-106 T 12-10-2018 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 SUPERFAMILY SSF55681 100 464 8.76E-92 T 12-10-2018 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 6 466 2.0E-195 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 Pfam PF01336 OB-fold nucleic acid binding domain 20 99 5.8E-9 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 460 4.4E-80 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 Gene3D G3DSA:2.40.50.140 1 105 3.9E-17 T 12-10-2018 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 1.8E-14 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 1.8E-14 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 1.8E-14 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 1.8E-14 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 5 466 44.924 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 IM45_914 d1af4fa511cd265ee4590daf0a726712 466 SUPERFAMILY SSF50249 16 102 4.29E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_692 45589426c45086423f1915bbc707af99 324 Gene3D G3DSA:1.10.10.10 1 86 1.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_692 45589426c45086423f1915bbc707af99 324 Gene3D G3DSA:3.40.190.10 167 267 5.9E-97 T 12-10-2018 IM45_692 45589426c45086423f1915bbc707af99 324 SUPERFAMILY SSF53850 91 322 8.69E-41 T 12-10-2018 IM45_692 45589426c45086423f1915bbc707af99 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 8.8E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_692 45589426c45086423f1915bbc707af99 324 SUPERFAMILY SSF46785 1 85 6.7E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_692 45589426c45086423f1915bbc707af99 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_692 45589426c45086423f1915bbc707af99 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_692 45589426c45086423f1915bbc707af99 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_692 45589426c45086423f1915bbc707af99 324 Pfam PF03466 LysR substrate binding domain 92 292 3.2E-38 T 12-10-2018 IPR005119 LysR, substrate-binding IM45_692 45589426c45086423f1915bbc707af99 324 Gene3D G3DSA:3.40.190.10 92 303 5.9E-97 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 Gene3D G3DSA:1.10.3860.10 8 440 1.2E-127 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 Hamap MF_02063 Proton/glutamate-aspartate symporter [gltP]. 14 441 42.164 T 12-10-2018 IPR034703 Proton/glutamate-aspartate symporter GltP GO:0006835|GO:0015293|GO:0016021 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 SUPERFAMILY SSF118215 22 425 7.72E-117 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 319 342 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 Pfam PF00375 Sodium:dicarboxylate symporter family 22 424 1.0E-111 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 56 71 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 94 119 4.1E-53 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 316 342 4.1E-53 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 378 398 4.1E-53 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 351 370 4.1E-53 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 168 190 4.1E-53 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 19 39 4.1E-53 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 64 84 4.1E-53 T 12-10-2018 IM45_256 b9c9a304cf8385d2b134657d75ba81b9 445 PRINTS PR00173 Glutamate-aspartate symporter signature 216 235 4.1E-53 T 12-10-2018 IM45_1395 d43e75e324b83839b23683329caef566 641 Gene3D G3DSA:2.40.50.920 27 103 2.1E-35 T 12-10-2018 IM45_1395 d43e75e324b83839b23683329caef566 641 Gene3D G3DSA:1.20.58.760 399 602 7.2E-68 T 12-10-2018 IM45_1395 d43e75e324b83839b23683329caef566 641 Pfam PF01434 Peptidase family M41 384 593 3.7E-80 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 IM45_1395 d43e75e324b83839b23683329caef566 641 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 1.3E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 IM45_1395 d43e75e324b83839b23683329caef566 641 Gene3D G3DSA:3.40.50.300 143 322 1.7E-70 T 12-10-2018 IM45_1395 d43e75e324b83839b23683329caef566 641 Pfam PF06480 FtsH Extracellular 8 96 5.5E-14 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 IM45_1395 d43e75e324b83839b23683329caef566 641 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 613 37.132 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 IM45_1395 d43e75e324b83839b23683329caef566 641 SMART SM00382 186 325 2.4E-26 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_1395 d43e75e324b83839b23683329caef566 641 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 IM45_1395 d43e75e324b83839b23683329caef566 641 SUPERFAMILY SSF140990 404 597 9.02E-70 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 IM45_1395 d43e75e324b83839b23683329caef566 641 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 103 595 3.6E-243 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 IM45_1395 d43e75e324b83839b23683329caef566 641 Gene3D G3DSA:1.10.8.60 324 398 4.1E-28 T 12-10-2018 IM45_1395 d43e75e324b83839b23683329caef566 641 SUPERFAMILY SSF52540 143 393 1.78E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 Pfam PF03466 LysR substrate binding domain 88 269 5.8E-14 T 12-10-2018 IPR005119 LysR, substrate-binding IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 SUPERFAMILY SSF46785 2 83 2.18E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 SUPERFAMILY SSF53850 89 269 4.89E-17 T 12-10-2018 IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_449 65768c9f99d8cecbbeeff0d77a4a45ba 274 Gene3D G3DSA:1.10.10.10 1 85 9.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_335 52d3a312381f1984287d66c23904e700 178 Gene3D G3DSA:1.10.520.20 2 107 6.5E-34 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 SUPERFAMILY SSF47928 3 104 1.22E-23 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 PRINTS PR00125 ATP synthase delta subunit signature 86 100 1.1E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 1.1E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 1.1E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 1.1E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.1E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 176 2.3E-51 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 8.0E-45 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 178 16.71 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_335 52d3a312381f1984287d66c23904e700 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 12-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_643 95b50b900433a0ac67b5320a463d78d3 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 278 9.4E-98 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_643 95b50b900433a0ac67b5320a463d78d3 299 Hamap MF_00367 GTPase Era [era]. 6 295 32.846 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_643 95b50b900433a0ac67b5320a463d78d3 299 SUPERFAMILY SSF52540 11 202 2.61E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_643 95b50b900433a0ac67b5320a463d78d3 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 168 6.8E-31 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_643 95b50b900433a0ac67b5320a463d78d3 299 Gene3D G3DSA:3.30.300.20 184 298 5.1E-38 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta IM45_643 95b50b900433a0ac67b5320a463d78d3 299 SUPERFAMILY SSF54814 181 295 1.05E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 IM45_643 95b50b900433a0ac67b5320a463d78d3 299 Gene3D G3DSA:3.40.50.300 5 182 6.1E-44 T 12-10-2018 IM45_643 95b50b900433a0ac67b5320a463d78d3 299 Pfam PF07650 KH domain 207 283 1.9E-15 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_643 95b50b900433a0ac67b5320a463d78d3 299 Pfam PF01926 50S ribosome-binding GTPase 11 123 3.4E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_511 3279c2e9c8f288367324e7b5af491627 433 PIRSF PIRSF001400 1 431 2.9E-187 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 430 8.7E-130 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 SMART SM01192 143 431 3.4E-198 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 429 3.9E-199 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 SMART SM01193 4 134 6.8E-88 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 SUPERFAMILY SSF51604 143 429 2.55E-120 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily IM45_511 3279c2e9c8f288367324e7b5af491627 433 Pfam PF03952 Enolase, N-terminal domain 4 134 6.3E-57 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 ProSitePatterns PS00164 Enolase signature. 340 353 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_511 3279c2e9c8f288367324e7b5af491627 433 Gene3D G3DSA:3.20.20.120 128 433 7.7E-127 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily IM45_511 3279c2e9c8f288367324e7b5af491627 433 PRINTS PR00148 Enolase signature 165 178 9.9E-42 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 PRINTS PR00148 Enolase signature 37 51 9.9E-42 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 PRINTS PR00148 Enolase signature 107 123 9.9E-42 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 PRINTS PR00148 Enolase signature 317 328 9.9E-42 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 PRINTS PR00148 Enolase signature 369 386 9.9E-42 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 PRINTS PR00148 Enolase signature 340 354 9.9E-42 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 SUPERFAMILY SSF54826 3 138 4.18E-56 T 12-10-2018 IM45_511 3279c2e9c8f288367324e7b5af491627 433 Hamap MF_00318 Enolase [eno]. 2 417 42.852 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 IM45_511 3279c2e9c8f288367324e7b5af491627 433 Gene3D G3DSA:3.30.390.10 1 127 9.8E-54 T 12-10-2018 IPR029017 Enolase-like, N-terminal IM45_107 01585e5b7cef9c9178404b4a750c0ac3 66 Pfam PF02597 ThiS family 3 66 8.5E-12 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 IM45_107 01585e5b7cef9c9178404b4a750c0ac3 66 Gene3D G3DSA:3.10.20.30 1 66 7.4E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily IM45_107 01585e5b7cef9c9178404b4a750c0ac3 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 1.3E-16 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis IM45_107 01585e5b7cef9c9178404b4a750c0ac3 66 SUPERFAMILY SSF54285 1 66 3.78E-15 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp IM45_081 a425a27a8dfbb59806005512a73d7d6b 132 Pfam PF00380 Ribosomal protein S9/S16 11 132 3.4E-44 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 IM45_081 a425a27a8dfbb59806005512a73d7d6b 132 Gene3D G3DSA:3.30.230.10 2 132 9.0E-52 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_081 a425a27a8dfbb59806005512a73d7d6b 132 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 2 132 32.747 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid IM45_081 a425a27a8dfbb59806005512a73d7d6b 132 SUPERFAMILY SSF54211 6 132 4.55E-46 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_521 4bd9caae970648e339b062a7649fcb25 765 Pfam PF00905 Penicillin binding protein transpeptidase domain 394 635 7.8E-26 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 IM45_521 4bd9caae970648e339b062a7649fcb25 765 SUPERFAMILY SSF56601 283 700 1.85E-105 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like IM45_521 4bd9caae970648e339b062a7649fcb25 765 Gene3D G3DSA:3.30.2060.10 32 121 1.7E-256 T 12-10-2018 IM45_521 4bd9caae970648e339b062a7649fcb25 765 PIRSF PIRSF002799 1 731 0.0 T 12-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_521 4bd9caae970648e339b062a7649fcb25 765 Pfam PF00912 Transglycosylase 130 301 1.6E-54 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_521 4bd9caae970648e339b062a7649fcb25 765 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 2 718 0.0 T 12-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_521 4bd9caae970648e339b062a7649fcb25 765 SUPERFAMILY SSF53955 118 323 5.91E-63 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily IM45_521 4bd9caae970648e339b062a7649fcb25 765 Gene3D G3DSA:1.10.3810.10 122 325 1.7E-256 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_521 4bd9caae970648e339b062a7649fcb25 765 Pfam PF14814 Bifunctional transglycosylase second domain 34 118 2.7E-25 T 12-10-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_521 4bd9caae970648e339b062a7649fcb25 765 Gene3D G3DSA:3.40.710.10 24 684 1.7E-256 T 12-10-2018 IM45_507 44d11a9a69148aa4c08ec8a32f46515d 115 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 2 92 2.4E-32 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 IM45_507 44d11a9a69148aa4c08ec8a32f46515d 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 114 4.4E-33 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 IM45_507 44d11a9a69148aa4c08ec8a32f46515d 115 PIRSF PIRSF006113 1 115 9.1E-51 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 IM45_507 44d11a9a69148aa4c08ec8a32f46515d 115 SUPERFAMILY SSF55620 2 115 1.28E-38 T 12-10-2018 IM45_507 44d11a9a69148aa4c08ec8a32f46515d 115 Gene3D G3DSA:3.30.479.10 1 115 9.1E-47 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 IM45_603 14496bc4612d167dec5cb2b0b646d2ac 230 Gene3D G3DSA:3.40.50.620 1 230 4.8E-77 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_603 14496bc4612d167dec5cb2b0b646d2ac 230 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 5 205 1.7E-79 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 IM45_603 14496bc4612d167dec5cb2b0b646d2ac 230 PIRSF PIRSF006293 1 224 2.0E-76 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 IM45_603 14496bc4612d167dec5cb2b0b646d2ac 230 SUPERFAMILY SSF52402 1 212 3.75E-61 T 12-10-2018 IM45_603 14496bc4612d167dec5cb2b0b646d2ac 230 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 218 46.349 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 IM45_603 14496bc4612d167dec5cb2b0b646d2ac 230 Pfam PF06508 Queuosine biosynthesis protein QueC 4 212 2.2E-77 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 IM45_017 293f978cd4f5fccebd9e121939b36311 430 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 422 32.694 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 IM45_017 293f978cd4f5fccebd9e121939b36311 430 PIRSF PIRSF001549 1 422 4.3E-122 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 IM45_017 293f978cd4f5fccebd9e121939b36311 430 SUPERFAMILY SSF52954 329 420 7.03E-21 T 12-10-2018 IM45_017 293f978cd4f5fccebd9e121939b36311 430 Gene3D G3DSA:3.30.930.10 2 322 2.5E-112 T 12-10-2018 IM45_017 293f978cd4f5fccebd9e121939b36311 430 Pfam PF13393 Histidyl-tRNA synthetase 10 313 8.3E-47 T 12-10-2018 IM45_017 293f978cd4f5fccebd9e121939b36311 430 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 412 3.1E-148 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 IM45_017 293f978cd4f5fccebd9e121939b36311 430 Gene3D G3DSA:3.40.50.800 328 421 1.0E-20 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily IM45_017 293f978cd4f5fccebd9e121939b36311 430 SUPERFAMILY SSF55681 5 321 6.37E-102 T 12-10-2018 IM45_017 293f978cd4f5fccebd9e121939b36311 430 Pfam PF03129 Anticodon binding domain 332 420 8.4E-8 T 12-10-2018 IPR004154 Anticodon-binding IM45_710 835cb902d537e8329e329a376aa10e3e 499 PIRSF PIRSF000110 1 491 4.5E-178 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 SUPERFAMILY SSF55347 176 488 1.31E-110 T 12-10-2018 IM45_710 835cb902d537e8329e329a376aa10e3e 499 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 186 4.1E-57 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 Gene3D G3DSA:3.30.360.10 176 476 3.2E-164 T 12-10-2018 IM45_710 835cb902d537e8329e329a376aa10e3e 499 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 176 182 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 SUPERFAMILY SSF51735 5 189 5.51E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_710 835cb902d537e8329e329a376aa10e3e 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 1.5E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 218 235 1.5E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 236 252 1.5E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 194 1.5E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 142 155 1.5E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 489 2.9E-192 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 188 488 4.7E-112 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_710 835cb902d537e8329e329a376aa10e3e 499 Gene3D G3DSA:3.40.50.720 12 437 3.2E-164 T 12-10-2018 IM45_710 835cb902d537e8329e329a376aa10e3e 499 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 489 86.748 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 223 38.531 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 59 68 - T 12-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 Gene3D G3DSA:3.40.470.10 4 237 2.5E-98 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 Pfam PF03167 Uracil DNA glycosylase superfamily 57 211 3.5E-23 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 SUPERFAMILY SSF52141 6 223 7.63E-89 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 SMART SM00987 51 212 9.2E-33 T 12-10-2018 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 SMART SM00986 51 212 9.2E-33 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 IM45_1342 7adbf163b76b9f866b102f152025fad4 239 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 216 6.9E-82 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 IM45_578 e768cf07a8c2ff2b67ec9bb990583120 224 Gene3D G3DSA:3.40.50.300 1 224 2.0E-77 T 12-10-2018 IM45_578 e768cf07a8c2ff2b67ec9bb990583120 224 SUPERFAMILY SSF52540 6 223 6.17E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_578 e768cf07a8c2ff2b67ec9bb990583120 224 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 31.928 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 IM45_578 e768cf07a8c2ff2b67ec9bb990583120 224 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 217 1.5E-83 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 IM45_578 e768cf07a8c2ff2b67ec9bb990583120 224 Pfam PF02224 Cytidylate kinase 8 221 2.3E-74 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 218 230 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 477 1.0E-159 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 Pfam PF00224 Pyruvate kinase, barrel domain 6 344 1.5E-122 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 Gene3D G3DSA:3.40.1380.20 342 473 3.1E-148 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 SUPERFAMILY SSF52935 329 479 2.62E-39 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 PRINTS PR01050 Pyruvate kinase family signature 300 318 1.6E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 PRINTS PR01050 Pyruvate kinase family signature 250 274 1.6E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 PRINTS PR01050 Pyruvate kinase family signature 319 335 1.6E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 PRINTS PR01050 Pyruvate kinase family signature 190 204 1.6E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 PRINTS PR01050 Pyruvate kinase family signature 223 249 1.6E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 PRINTS PR01050 Pyruvate kinase family signature 63 79 1.6E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 PRINTS PR01050 Pyruvate kinase family signature 275 299 1.6E-50 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 SUPERFAMILY SSF51621 4 344 6.28E-85 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 SUPERFAMILY SSF50800 74 168 5.41E-23 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 Gene3D G3DSA:3.20.20.60 6 341 3.1E-148 T 12-10-2018 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 Gene3D G3DSA:2.40.33.10 74 172 3.1E-148 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_712 a9cd940d1859d2e5b86285074c6156e6 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 477 8.0E-28 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 244 6.6E-38 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 Gene3D G3DSA:3.40.47.10 258 403 1.4E-48 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 SUPERFAMILY SSF53901 213 402 3.46E-60 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 SUPERFAMILY SSF53901 1 251 2.16E-60 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 359 1.8E-28 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 Gene3D G3DSA:3.40.47.10 6 257 1.7E-58 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 IM45_815 d2ada990f823c7c5590e3e7366910ad1 403 SMART SM00825 Beta-ketoacyl synthase 4 403 1.2E-11 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Gene3D G3DSA:1.10.268.10 372 496 5.6E-224 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 843 0.0 T 12-10-2018 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 746 792 1.6E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 591 640 5.5E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 648 691 9.1E-6 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 696 740 3.9E-15 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 541 587 2.6E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 796 842 4.0E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 SUPERFAMILY SSF56719 32 524 4.05E-174 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Gene3D G3DSA:2.120.10.90 538 844 3.9E-125 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 SUPERFAMILY SSF101904 536 847 7.72E-108 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Gene3D G3DSA:3.30.1360.40 238 335 5.6E-224 T 12-10-2018 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Gene3D G3DSA:3.90.199.10 35 524 5.6E-224 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 34 509 2.4E-147 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 SMART SM00434 13 502 1.0E-275 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 IM45_871 53e8bdc5e34ca3bd59c6bbea065c3f9e 848 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 844 23.8 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 IM45_1289 dbce3f9da1c338422db20a0475efdd24 294 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 51 287 4.6E-86 T 12-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 IM45_1289 dbce3f9da1c338422db20a0475efdd24 294 Pfam PF02666 Phosphatidylserine decarboxylase 65 286 7.5E-57 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 IM45_1289 dbce3f9da1c338422db20a0475efdd24 294 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 12 289 46.305 T 12-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 IM45_869 5cde898e5e9fbcf7b2b09fec853bcf99 244 Pfam PF13489 Methyltransferase domain 60 212 6.5E-23 T 12-10-2018 IM45_869 5cde898e5e9fbcf7b2b09fec853bcf99 244 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 19 243 35.55 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 IM45_869 5cde898e5e9fbcf7b2b09fec853bcf99 244 Gene3D G3DSA:3.40.50.150 19 243 1.9E-71 T 12-10-2018 IM45_869 5cde898e5e9fbcf7b2b09fec853bcf99 244 SUPERFAMILY SSF53335 23 239 8.44E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_869 5cde898e5e9fbcf7b2b09fec853bcf99 244 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 19 237 6.0E-83 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 IM45_061 50a762004cc310208e0492977630ae91 456 Gene3D G3DSA:3.30.870.10 23 452 6.1E-165 T 12-10-2018 IM45_061 50a762004cc310208e0492977630ae91 456 Pfam PF13091 PLD-like domain 263 409 4.8E-20 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 IM45_061 50a762004cc310208e0492977630ae91 456 Pfam PF13091 PLD-like domain 45 161 1.3E-6 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 IM45_061 50a762004cc310208e0492977630ae91 456 SUPERFAMILY SSF56024 15 198 1.22E-25 T 12-10-2018 IM45_061 50a762004cc310208e0492977630ae91 456 Gene3D G3DSA:3.30.870.10 29 237 6.1E-165 T 12-10-2018 IM45_061 50a762004cc310208e0492977630ae91 456 PIRSF PIRSF000850 1 456 2.6E-210 T 12-10-2018 IM45_061 50a762004cc310208e0492977630ae91 456 SUPERFAMILY SSF56024 258 400 6.59E-21 T 12-10-2018 IM45_061 50a762004cc310208e0492977630ae91 456 SMART SM00155 138 164 0.021 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 IM45_061 50a762004cc310208e0492977630ae91 456 SMART SM00155 357 384 5.2E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 IM45_1371 cdf6baa2585addb5406b921f79a0738f 133 Gene3D G3DSA:3.40.50.10220 33 133 6.0E-26 T 12-10-2018 IPR036654 DNA polymerase III, psi subunit superfamily GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1371 cdf6baa2585addb5406b921f79a0738f 133 ProDom PD032475 DNA POLYMERASE PSI SUBUNIT III TRANSFERASE NUCLEOTIDYLTRANSFERASE III 3D-STRUCTURE DNA-DIRECTED 52 127 5.0E-11 T 12-10-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1371 cdf6baa2585addb5406b921f79a0738f 133 SUPERFAMILY SSF102220 30 132 2.09E-21 T 12-10-2018 IPR036654 DNA polymerase III, psi subunit superfamily GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1371 cdf6baa2585addb5406b921f79a0738f 133 PIRSF PIRSF029225 2 133 2.3E-34 T 12-10-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1371 cdf6baa2585addb5406b921f79a0738f 133 Pfam PF03603 DNA polymerase III psi subunit 4 128 6.4E-36 T 12-10-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_779 a06c37795a4065eb6d26185a244335fb 179 SUPERFAMILY SSF56053 2 84 2.06E-20 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_779 a06c37795a4065eb6d26185a244335fb 179 SUPERFAMILY SSF56053 85 179 2.45E-30 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_779 a06c37795a4065eb6d26185a244335fb 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 156 164 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_779 a06c37795a4065eb6d26185a244335fb 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 178 7.2E-64 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 IM45_779 a06c37795a4065eb6d26185a244335fb 179 Gene3D G3DSA:3.90.930.12 1 84 4.9E-26 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_779 a06c37795a4065eb6d26185a244335fb 179 PRINTS PR00059 Ribosomal protein L6 signature 73 98 3.6E-26 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 IM45_779 a06c37795a4065eb6d26185a244335fb 179 PRINTS PR00059 Ribosomal protein L6 signature 101 117 3.6E-26 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 IM45_779 a06c37795a4065eb6d26185a244335fb 179 PRINTS PR00059 Ribosomal protein L6 signature 143 164 3.6E-26 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 IM45_779 a06c37795a4065eb6d26185a244335fb 179 PIRSF PIRSF002162 1 179 8.5E-45 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_779 a06c37795a4065eb6d26185a244335fb 179 Gene3D G3DSA:3.90.930.12 85 179 3.7E-32 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_779 a06c37795a4065eb6d26185a244335fb 179 Pfam PF00347 Ribosomal protein L6 11 84 1.6E-12 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_779 a06c37795a4065eb6d26185a244335fb 179 Pfam PF00347 Ribosomal protein L6 92 166 1.8E-13 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 Gene3D G3DSA:1.10.40.30 408 465 2.4E-29 T 12-10-2018 IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 462 88.539 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 Pfam PF10415 Fumarase C C-terminus 408 460 1.7E-24 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 SUPERFAMILY SSF48557 3 460 1.88E-153 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 Gene3D G3DSA:1.10.275.10 5 138 1.1E-53 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 Pfam PF00206 Lyase 14 342 1.5E-113 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 1.6E-33 T 12-10-2018 IPR000362 Fumarate lyase family IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 1.6E-33 T 12-10-2018 IPR000362 Fumarate lyase family IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 1.6E-33 T 12-10-2018 IPR000362 Fumarate lyase family IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 1.6E-33 T 12-10-2018 IPR000362 Fumarate lyase family IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 5 461 5.3E-241 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 IM45_937 6dd29a72156ec30fc1c3416e5e14d090 465 Gene3D G3DSA:1.20.200.10 139 407 3.8E-117 T 12-10-2018 IM45_1025 f25154a350faed2b066bffc69f59fa2a 407 Gene3D G3DSA:3.40.640.10 36 298 1.1E-162 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_1025 f25154a350faed2b066bffc69f59fa2a 407 Gene3D G3DSA:3.90.1150.10 8 399 1.1E-162 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_1025 f25154a350faed2b066bffc69f59fa2a 407 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 218 237 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site IM45_1025 f25154a350faed2b066bffc69f59fa2a 407 SUPERFAMILY SSF53383 4 402 2.84E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_1025 f25154a350faed2b066bffc69f59fa2a 407 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 6 405 3.7E-176 T 12-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 IM45_1025 f25154a350faed2b066bffc69f59fa2a 407 Pfam PF00266 Aminotransferase class-V 25 395 1.1E-147 T 12-10-2018 IPR000192 Aminotransferase class V domain IM45_615 cdde871416f7735eefebeb51f92e30e2 296 Pfam PF06481 COX Aromatic Rich Motif 240 284 5.2E-16 T 12-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 IM45_615 cdde871416f7735eefebeb51f92e30e2 296 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 149 220 3.9E-6 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_615 cdde871416f7735eefebeb51f92e30e2 296 Gene3D G3DSA:2.60.40.420 114 283 1.9E-56 T 12-10-2018 IPR008972 Cupredoxin IM45_615 cdde871416f7735eefebeb51f92e30e2 296 PIRSF PIRSF000292 1 296 1.3E-125 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 IM45_615 cdde871416f7735eefebeb51f92e30e2 296 SUPERFAMILY SSF81464 30 117 1.21E-22 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_615 cdde871416f7735eefebeb51f92e30e2 296 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 15 240 4.4E-108 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 IM45_615 cdde871416f7735eefebeb51f92e30e2 296 Gene3D G3DSA:1.10.287.90 28 113 1.5E-30 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_615 cdde871416f7735eefebeb51f92e30e2 296 SUPERFAMILY SSF49503 122 282 6.09E-51 T 12-10-2018 IPR008972 Cupredoxin IM45_682 a55c0d5f527d9dc717d022687393f8b0 244 SMART SM00934 13 236 1.6E-80 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_682 a55c0d5f527d9dc717d022687393f8b0 244 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 11 241 36.383 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_682 a55c0d5f527d9dc717d022687393f8b0 244 Gene3D G3DSA:3.20.20.70 8 244 1.2E-75 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_682 a55c0d5f527d9dc717d022687393f8b0 244 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 14 233 2.8E-52 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_682 a55c0d5f527d9dc717d022687393f8b0 244 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 65 78 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_682 a55c0d5f527d9dc717d022687393f8b0 244 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 12 230 3.9E-46 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_682 a55c0d5f527d9dc717d022687393f8b0 244 SUPERFAMILY SSF51366 11 237 1.3E-69 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 23.08 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 1.4E-41 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 SUPERFAMILY SSF48300 3 57 1.02E-12 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 Gene3D G3DSA:3.30.1390.10 51 121 3.6E-29 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 SUPERFAMILY SSF54736 50 121 5.76E-23 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 42 2.0E-11 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 Gene3D G3DSA:1.20.5.710 2 50 3.9E-19 T 12-10-2018 IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 8.9E-28 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1103 2ccc69c25175bf4acd8de15cf67f5ffe 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 5.0E-21 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1155 3d790348b4e1a60bad978912aa4712d3 106 Hamap MF_00910 Cell division protein FtsL [ftsL]. 20 105 14.87 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 IM45_1155 3d790348b4e1a60bad978912aa4712d3 106 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 21 101 3.4E-25 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 IM45_1155 3d790348b4e1a60bad978912aa4712d3 106 Pfam PF04999 Cell division protein FtsL 10 104 8.3E-31 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 SUPERFAMILY SSF52540 77 348 3.55E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 Gene3D G3DSA:2.40.10.170 2 75 3.7E-30 T 12-10-2018 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 333 342 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 SMART SM00382 142 405 8.5E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 SUPERFAMILY SSF50615 1 75 9.68E-25 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 SUPERFAMILY SSF47917 345 459 7.85E-52 T 12-10-2018 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 73 3.0E-18 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 130 342 3.0E-64 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 460 55.629 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 Gene3D G3DSA:1.10.1140.10 345 460 3.0E-55 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 Gene3D G3DSA:3.40.50.300 76 344 8.5E-112 T 12-10-2018 IM45_329 9d1bf9da53d4e71ce901df522f583a31 460 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 460 1.3E-252 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 IM45_007 f90bd8a6c4af694dc9f20e02ea19a9ff 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 51.338 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 IM45_007 f90bd8a6c4af694dc9f20e02ea19a9ff 417 PIRSF PIRSF000412 1 417 7.2E-167 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 IM45_007 f90bd8a6c4af694dc9f20e02ea19a9ff 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 IM45_007 f90bd8a6c4af694dc9f20e02ea19a9ff 417 Pfam PF00464 Serine hydroxymethyltransferase 9 386 2.4E-179 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 IM45_007 f90bd8a6c4af694dc9f20e02ea19a9ff 417 Gene3D G3DSA:3.40.640.10 37 289 2.6E-180 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_007 f90bd8a6c4af694dc9f20e02ea19a9ff 417 SUPERFAMILY SSF53383 7 416 4.7E-177 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_007 f90bd8a6c4af694dc9f20e02ea19a9ff 417 Gene3D G3DSA:3.90.1150.10 11 396 2.6E-180 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_161 20e61df0854d47dae92ea4402ba43597 685 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 669 2.0E-243 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Gene3D G3DSA:1.10.287.610 1 68 1.5E-25 T 12-10-2018 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Gene3D G3DSA:2.20.70.80 392 431 7.3E-8 T 12-10-2018 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Gene3D G3DSA:2.40.50.140 319 391 7.1E-33 T 12-10-2018 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 600 671 2.0E-12 T 12-10-2018 IPR001357 BRCT domain IM45_161 20e61df0854d47dae92ea4402ba43597 685 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 319 2.0E-124 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Hamap MF_01588 DNA ligase [ligA]. 1 673 48.0 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 323 399 3.6E-33 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 IM45_161 20e61df0854d47dae92ea4402ba43597 685 SUPERFAMILY SSF52113 599 674 9.16E-17 T 12-10-2018 IPR036420 BRCT domain superfamily IM45_161 20e61df0854d47dae92ea4402ba43597 685 SUPERFAMILY SSF50249 319 400 6.85E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_161 20e61df0854d47dae92ea4402ba43597 685 Gene3D G3DSA:1.10.150.20 433 506 7.5E-26 T 12-10-2018 IM45_161 20e61df0854d47dae92ea4402ba43597 685 SMART SM00292 599 676 4.8E-10 T 12-10-2018 IPR001357 BRCT domain IM45_161 20e61df0854d47dae92ea4402ba43597 685 Pfam PF12826 Helix-hairpin-helix motif 511 574 2.3E-19 T 12-10-2018 IM45_161 20e61df0854d47dae92ea4402ba43597 685 PIRSF PIRSF001604 1 677 7.0E-240 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 IM45_161 20e61df0854d47dae92ea4402ba43597 685 SUPERFAMILY SSF56091 2 317 7.2E-117 T 12-10-2018 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Gene3D G3DSA:1.10.150.20 507 589 5.0E-24 T 12-10-2018 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 408 435 1.1E-6 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 IM45_161 20e61df0854d47dae92ea4402ba43597 685 Gene3D G3DSA:3.40.50.10190 593 675 1.1E-22 T 12-10-2018 IPR036420 BRCT domain superfamily IM45_161 20e61df0854d47dae92ea4402ba43597 685 SUPERFAMILY SSF47781 405 581 1.59E-49 T 12-10-2018 IPR010994 RuvA domain 2-like IM45_161 20e61df0854d47dae92ea4402ba43597 685 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site IM45_161 20e61df0854d47dae92ea4402ba43597 685 SMART SM00532 3 449 5.7E-241 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 IM45_161 20e61df0854d47dae92ea4402ba43597 685 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 332 347 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site IM45_161 20e61df0854d47dae92ea4402ba43597 685 Gene3D G3DSA:3.30.470.90 69 318 2.9E-92 T 12-10-2018 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 2.9E-43 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 SUPERFAMILY SSF52540 96 381 3.54E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 508 48.2 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 SUPERFAMILY SSF50615 10 94 2.16E-25 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 Gene3D G3DSA:1.20.150.20 383 510 7.4E-44 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 Gene3D G3DSA:3.40.50.300 94 382 2.1E-127 T 12-10-2018 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 Gene3D G3DSA:2.40.30.20 1 93 3.8E-28 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 1.4E-71 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 SUPERFAMILY SSF47917 383 508 7.85E-43 T 12-10-2018 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 92 5.7E-13 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 IM45_333 71a05c4d311e8bd8e438f6856ae6fdf2 510 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 508 3.8E-246 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_218 1b7d38c0167bbd3eb450e747764029e5 171 Gene3D G3DSA:3.40.50.360 3 171 2.2E-55 T 12-10-2018 IPR029039 Flavoprotein-like superfamily IM45_218 1b7d38c0167bbd3eb450e747764029e5 171 TIGRFAM TIGR01752 flav_long: flavodoxin 4 167 9.5E-71 T 12-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 IM45_218 1b7d38c0167bbd3eb450e747764029e5 171 PIRSF PIRSF038996 1 171 4.1E-68 T 12-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 IM45_218 1b7d38c0167bbd3eb450e747764029e5 171 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 12-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 IM45_218 1b7d38c0167bbd3eb450e747764029e5 171 SUPERFAMILY SSF52218 3 165 2.25E-50 T 12-10-2018 IPR029039 Flavoprotein-like superfamily IM45_218 1b7d38c0167bbd3eb450e747764029e5 171 Pfam PF00258 Flavodoxin 6 160 2.0E-31 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 IM45_345 9c69251c0f4083fd76c03446827e015b 327 Gene3D G3DSA:3.30.70.1400 28 114 1.9E-55 T 12-10-2018 IM45_345 9c69251c0f4083fd76c03446827e015b 327 Gene3D G3DSA:3.30.70.1630 25 195 1.9E-55 T 12-10-2018 IM45_345 9c69251c0f4083fd76c03446827e015b 327 SUPERFAMILY SSF103025 19 243 5.34E-60 T 12-10-2018 IM45_345 9c69251c0f4083fd76c03446827e015b 327 Pfam PF01571 Aminomethyltransferase folate-binding domain 31 139 9.9E-8 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain IM45_345 9c69251c0f4083fd76c03446827e015b 327 Hamap MF_01175 tRNA-modifying protein YgfZ [ygfZ]. 1 323 45.6 T 12-10-2018 IPR023758 tRNA-modifying protein YgfZ GO:0005542|GO:0009451 IM45_345 9c69251c0f4083fd76c03446827e015b 327 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 188 252 4.7E-26 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site IM45_345 9c69251c0f4083fd76c03446827e015b 327 SUPERFAMILY SSF101790 245 324 3.73E-20 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal IM45_345 9c69251c0f4083fd76c03446827e015b 327 Gene3D G3DSA:2.40.30.160 198 319 1.4E-38 T 12-10-2018 IM45_345 9c69251c0f4083fd76c03446827e015b 327 PIRSF PIRSF006487 179 288 0.16 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 IM45_345 9c69251c0f4083fd76c03446827e015b 327 PIRSF PIRSF006487 23 152 2.3E-7 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 313 4.5E-28 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 121 1.2E-48 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 Gene3D G3DSA:3.40.50.2020 148 290 2.6E-132 T 12-10-2018 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 SMART SM01400 4 121 2.5E-73 T 12-10-2018 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 Gene3D G3DSA:3.40.50.2020 7 302 2.6E-132 T 12-10-2018 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 4 314 48.618 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 SUPERFAMILY SSF53271 69 306 1.9E-63 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 IM45_672 2137dc04bbef8f3f72bfadc60c59d3de 315 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 314 1.8E-122 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 IM45_103 1199d73e5209fc4212252c065e56fc67 215 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 24 200 4.7E-54 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 IM45_103 1199d73e5209fc4212252c065e56fc67 215 SUPERFAMILY SSF51391 4 211 7.06E-64 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 IM45_103 1199d73e5209fc4212252c065e56fc67 215 Gene3D G3DSA:3.20.20.70 8 213 3.0E-60 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_103 1199d73e5209fc4212252c065e56fc67 215 Pfam PF02581 Thiamine monophosphate synthase 22 190 8.4E-55 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 IM45_103 1199d73e5209fc4212252c065e56fc67 215 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 208 20.34 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 IM45_570 d20e62d2898990ea5454dc4d0574aca6 258 SMART SM00382 28 221 6.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_570 d20e62d2898990ea5454dc4d0574aca6 258 Gene3D G3DSA:3.40.50.300 2 257 1.0E-75 T 12-10-2018 IM45_570 d20e62d2898990ea5454dc4d0574aca6 258 PIRSF PIRSF039085 1 249 4.1E-105 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 IM45_570 d20e62d2898990ea5454dc4d0574aca6 258 Pfam PF00005 ABC transporter 19 173 5.8E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_570 d20e62d2898990ea5454dc4d0574aca6 258 SUPERFAMILY SSF52540 4 243 1.61E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_570 d20e62d2898990ea5454dc4d0574aca6 258 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 394 1.4E-232 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 60.574 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 Gene3D G3DSA:2.40.30.10 338 393 1.4E-28 T 12-10-2018 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 2.6E-15 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 1.5E-59 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.2E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.2E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.2E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.2E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.2E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 1.6E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 SUPERFAMILY SSF52540 8 226 5.72E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 SUPERFAMILY SSF50447 205 301 4.32E-30 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 SUPERFAMILY SSF50465 298 393 4.89E-36 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 Gene3D G3DSA:2.40.30.10 206 334 6.6E-52 T 12-10-2018 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 Gene3D G3DSA:3.40.50.300 1 203 9.7E-72 T 12-10-2018 IM45_1091 773911d4803774fa4f570dbb7d3dc778 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 8.8E-34 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal IM45_739 d4d3fa549d04cda1af6d9b28090ba653 242 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 IM45_739 d4d3fa549d04cda1af6d9b28090ba653 242 Gene3D G3DSA:3.40.50.300 1 236 3.2E-67 T 12-10-2018 IM45_739 d4d3fa549d04cda1af6d9b28090ba653 242 SMART SM00382 27 218 7.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_739 d4d3fa549d04cda1af6d9b28090ba653 242 SUPERFAMILY SSF52540 3 229 2.35E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_739 d4d3fa549d04cda1af6d9b28090ba653 242 Pfam PF00005 ABC transporter 20 170 3.0E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 Gene3D G3DSA:1.10.730.20 640 929 9.5E-91 T 12-10-2018 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 Pfam PF08264 Anticodon-binding domain of tRNA 685 841 3.7E-29 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 561 570 7.4E-34 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 7.4E-34 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 526 539 7.4E-34 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 238 261 7.4E-34 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 401 416 7.4E-34 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 SUPERFAMILY SSF47323 652 929 6.35E-71 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 843 2.0E-285 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 Pfam PF06827 Zinc finger found in FPG and IleRS 898 925 1.3E-8 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 Gene3D G3DSA:3.90.740.10 195 408 1.7E-225 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 641 1.5E-211 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 Gene3D G3DSA:3.40.50.620 26 629 1.7E-225 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_1224 294a86b83663685f6bb97b5b0c724125 938 SUPERFAMILY SSF50677 207 403 4.29E-50 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 929 20.992 T 12-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 IM45_1224 294a86b83663685f6bb97b5b0c724125 938 SUPERFAMILY SSF52374 3 647 3.18E-134 T 12-10-2018 IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 7.6E-47 T 12-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 455 6.5E-139 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 SUPERFAMILY SSF48557 10 454 2.98E-99 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 4.8E-16 T 12-10-2018 IPR000362 Fumarate lyase family IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 4.8E-16 T 12-10-2018 IPR000362 Fumarate lyase family IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 4.8E-16 T 12-10-2018 IPR000362 Fumarate lyase family IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 4.8E-16 T 12-10-2018 IPR000362 Fumarate lyase family IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 Gene3D G3DSA:1.10.275.10 1 117 2.9E-49 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 Gene3D G3DSA:1.10.40.30 382 445 4.9E-152 T 12-10-2018 IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 Gene3D G3DSA:1.20.200.10 118 446 4.9E-152 T 12-10-2018 IM45_946 27ef180a4074774ebf7827ffb68e23ad 468 Pfam PF00206 Lyase 14 312 1.4E-67 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 368 7.1E-106 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 PIRSF PIRSF000804 1 368 5.9E-108 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 245 4.3E-36 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 SUPERFAMILY SSF55979 248 368 3.4E-35 T 12-10-2018 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 Gene3D G3DSA:3.10.150.10 124 249 1.4E-35 T 12-10-2018 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 367 1.4E-38 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 SUPERFAMILY SSF55979 125 246 1.86E-31 T 12-10-2018 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 Gene3D G3DSA:3.10.150.10 1 123 5.7E-35 T 12-10-2018 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 SUPERFAMILY SSF55979 1 121 1.76E-22 T 12-10-2018 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 Gene3D G3DSA:3.10.150.10 250 368 6.8E-37 T 12-10-2018 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 SMART SM00480 17 364 9.6E-128 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 IM45_307 786edb3cf45313c73ceda4ec041e1c22 368 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 7.1E-30 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 Gene3D G3DSA:1.10.8.60 8 238 1.0E-98 T 12-10-2018 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 Gene3D G3DSA:1.20.272.10 242 365 1.8E-40 T 12-10-2018 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 Pfam PF13177 DNA polymerase III, delta subunit 20 178 3.3E-40 T 12-10-2018 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 Gene3D G3DSA:3.40.50.300 13 177 1.0E-98 T 12-10-2018 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 367 4.9E-26 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 SMART SM00382 37 178 2.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 Gene3D G3DSA:3.30.300.150 468 595 5.2E-38 T 12-10-2018 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 7.7E-129 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 SUPERFAMILY SSF48019 246 366 2.21E-28 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 474 610 5.1E-47 T 12-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_272 7f8bfb8ceb20ccf72507f797912efeb2 613 SUPERFAMILY SSF52540 34 223 9.36E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_011 97fa823e88b5c9a78f489474ffcebbe3 387 PIRSF PIRSF005572 2 383 4.1E-129 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 IM45_011 97fa823e88b5c9a78f489474ffcebbe3 387 Gene3D G3DSA:3.90.1150.10 5 376 3.9E-155 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_011 97fa823e88b5c9a78f489474ffcebbe3 387 Pfam PF00266 Aminotransferase class-V 5 368 3.5E-83 T 12-10-2018 IPR000192 Aminotransferase class V domain IM45_011 97fa823e88b5c9a78f489474ffcebbe3 387 Gene3D G3DSA:3.40.640.10 16 262 3.9E-155 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_011 97fa823e88b5c9a78f489474ffcebbe3 387 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site IM45_011 97fa823e88b5c9a78f489474ffcebbe3 387 SUPERFAMILY SSF53383 5 372 4.44E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Gene3D G3DSA:3.40.50.620 28 247 4.0E-102 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 SUPERFAMILY SSF52374 14 337 5.35E-99 T 12-10-2018 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 530 3.7E-59 T 12-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 554 49.786 T 12-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 9.7E-8 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 9.7E-8 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 9.7E-8 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Gene3D G3DSA:3.90.800.10 101 209 4.0E-102 T 12-10-2018 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 554 2.8E-267 T 12-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Gene3D G3DSA:1.10.1160.10 261 339 1.6E-33 T 12-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 SUPERFAMILY SSF50715 340 552 3.09E-68 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Gene3D G3DSA:2.40.240.10 348 464 6.0E-42 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 8.2E-121 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 IM45_216 a665c2795fef9ebcc47429bfcc95fbd8 560 Gene3D G3DSA:2.40.240.10 465 552 2.9E-25 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 SMART SM00861 320 485 6.0E-65 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 SUPERFAMILY SSF52518 318 504 1.81E-55 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 SUPERFAMILY SSF52518 13 382 4.06E-75 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 SUPERFAMILY SSF52922 493 620 6.94E-29 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 Gene3D G3DSA:3.40.50.920 496 621 1.3E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 621 44.952 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 ProSitePatterns PS00802 Transketolase signature 2. 426 442 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 15 283 9.4E-114 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 620 2.5E-294 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 Gene3D G3DSA:3.40.50.970 318 493 4.4E-63 T 12-10-2018 IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 Pfam PF02780 Transketolase, C-terminal domain 496 609 6.1E-24 T 12-10-2018 IPR033248 Transketolase, C-terminal domain IM45_633 8f9cd4e69871144b4b3f0e101077fe9f 621 Pfam PF02779 Transketolase, pyrimidine binding domain 321 481 1.4E-36 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Gene3D G3DSA:1.10.860.10 439 583 6.7E-50 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 SUPERFAMILY SSF56731 116 427 9.68E-110 T 12-10-2018 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Pfam PF08278 DNA primase DnaG DnaB-binding 453 576 7.3E-32 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Hamap MF_00974 DNA primase [dnaG]. 4 578 28.854 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 SMART SM00400 36 90 1.8E-32 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Gene3D G3DSA:3.90.980.10 116 240 9.2E-43 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Pfam PF01807 CHC2 zinc finger 6 100 1.5E-37 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 SUPERFAMILY SSF117023 449 580 2.62E-44 T 12-10-2018 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 8.9E-147 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Pfam PF10410 DnaB-helicase binding domain of primase 370 421 7.8E-11 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Pfam PF13662 Toprim domain 260 324 5.1E-14 T 12-10-2018 IPR006171 TOPRIM domain IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 PIRSF PIRSF002811 2 585 7.7E-142 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Gene3D G3DSA:3.40.1360.10 241 367 1.9E-43 T 12-10-2018 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 SMART SM00493 259 330 1.5E-21 T 12-10-2018 IPR006171 TOPRIM domain IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 SMART SM00766 452 577 4.3E-47 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Gene3D G3DSA:1.20.50.20 368 426 3.7E-26 T 12-10-2018 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Gene3D G3DSA:3.90.580.10 1 101 5.7E-35 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 SUPERFAMILY SSF57783 4 100 3.23E-32 T 12-10-2018 IM45_1349 dc16b629bef3c614b451cee23fa1e806 585 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 251 3.2E-40 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal IM45_1015 0b850fe3d886b74fba1247de640a4bfa 506 SUPERFAMILY SSF103473 11 496 1.31E-62 T 12-10-2018 IPR036259 MFS transporter superfamily IM45_1015 0b850fe3d886b74fba1247de640a4bfa 506 Gene3D G3DSA:1.20.1250.20 262 497 5.5E-13 T 12-10-2018 IM45_1015 0b850fe3d886b74fba1247de640a4bfa 506 Gene3D G3DSA:1.20.1720.10 17 221 4.6E-44 T 12-10-2018 IM45_1015 0b850fe3d886b74fba1247de640a4bfa 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 495 2.2E-142 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 IM45_1015 0b850fe3d886b74fba1247de640a4bfa 506 Pfam PF07690 Major Facilitator Superfamily 20 413 1.4E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 IM45_992 fd1bda572b22777c6de38415e5e60338 270 PIRSF PIRSF003092 1 270 2.7E-95 T 12-10-2018 IPR025501 ATP binding protein MinD IM45_992 fd1bda572b22777c6de38415e5e60338 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 1.1E-106 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 IM45_992 fd1bda572b22777c6de38415e5e60338 270 Gene3D G3DSA:3.40.50.300 1 260 9.2E-72 T 12-10-2018 IM45_992 fd1bda572b22777c6de38415e5e60338 270 SUPERFAMILY SSF52540 1 268 6.07E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_992 fd1bda572b22777c6de38415e5e60338 270 Pfam PF13614 AAA domain 3 168 4.5E-19 T 12-10-2018 IPR025669 AAA domain IM45_726 cfb7f908c79f72f4929c85df37a90141 248 SUPERFAMILY SSF89550 3 236 1.96E-57 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 IM45_726 cfb7f908c79f72f4929c85df37a90141 248 Gene3D G3DSA:3.20.20.140 1 245 7.9E-62 T 12-10-2018 IM45_726 cfb7f908c79f72f4929c85df37a90141 248 SMART SM00481 4 78 1.5E-13 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal IM45_726 cfb7f908c79f72f4929c85df37a90141 248 Pfam PF02811 PHP domain 5 109 2.7E-8 T 12-10-2018 IPR004013 PHP domain GO:0003824 IM45_572 e84dcae33bbe37be49b86e5542680105 239 PIRSF PIRSF000709 161 235 0.0071 T 12-10-2018 IM45_572 e84dcae33bbe37be49b86e5542680105 239 PIRSF PIRSF000709 1 110 6.3E-8 T 12-10-2018 IM45_572 e84dcae33bbe37be49b86e5542680105 239 SUPERFAMILY SSF53254 1 230 4.21E-71 T 12-10-2018 IPR029033 Histidine phosphatase superfamily IM45_572 e84dcae33bbe37be49b86e5542680105 239 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 1 238 9.9E-113 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 IM45_572 e84dcae33bbe37be49b86e5542680105 239 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 2 11 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 IM45_572 e84dcae33bbe37be49b86e5542680105 239 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 224 43.068 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 IM45_572 e84dcae33bbe37be49b86e5542680105 239 SMART SM00855 1 185 6.3E-20 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 IM45_572 e84dcae33bbe37be49b86e5542680105 239 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 119 6.6E-29 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 IM45_572 e84dcae33bbe37be49b86e5542680105 239 Gene3D G3DSA:3.40.50.1240 1 239 3.9E-82 T 12-10-2018 IPR029033 Histidine phosphatase superfamily IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 8.8E-29 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 PIRSF PIRSF003101 2 418 3.2E-149 T 12-10-2018 IPR020823 Cell division protein FtsA IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 Gene3D G3DSA:3.90.640.10 235 300 9.9E-113 T 12-10-2018 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 Pfam PF14450 Cell division protein FtsA 207 381 1.1E-23 T 12-10-2018 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 SUPERFAMILY SSF53067 198 384 6.79E-47 T 12-10-2018 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 385 1.3E-156 T 12-10-2018 IPR020823 Cell division protein FtsA IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 Gene3D G3DSA:3.30.420.40 13 379 9.9E-113 T 12-10-2018 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 SMART SM00842 10 196 4.1E-90 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 SUPERFAMILY SSF53067 8 223 3.63E-61 T 12-10-2018 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 Gene3D G3DSA:3.30.420.40 197 359 9.9E-113 T 12-10-2018 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 Gene3D G3DSA:3.30.1490.110 87 169 9.9E-113 T 12-10-2018 IM45_1135 aafdafa78ca443d80e427ecfaa87b9ae 418 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 418 28.783 T 12-10-2018 IPR020823 Cell division protein FtsA IM45_781 ac064ca12ee7cad37ca1a20b93cad7c8 119 SUPERFAMILY SSF53137 5 117 2.4E-47 T 12-10-2018 IM45_781 ac064ca12ee7cad37ca1a20b93cad7c8 119 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 5 119 1.6E-39 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_781 ac064ca12ee7cad37ca1a20b93cad7c8 119 Gene3D G3DSA:3.30.420.100 3 119 7.8E-42 T 12-10-2018 IM45_781 ac064ca12ee7cad37ca1a20b93cad7c8 119 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 4 119 25.019 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_781 ac064ca12ee7cad37ca1a20b93cad7c8 119 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 4 119 1.2E-38 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_960 3103241518f872006ed955d7420869e9 334 SUPERFAMILY SSF52540 4 207 3.46E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_960 3103241518f872006ed955d7420869e9 334 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 14 202 9.6E-55 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_960 3103241518f872006ed955d7420869e9 334 Pfam PF13177 DNA polymerase III, delta subunit 16 164 1.3E-39 T 12-10-2018 IM45_960 3103241518f872006ed955d7420869e9 334 Gene3D G3DSA:1.20.272.10 209 327 2.2E-32 T 12-10-2018 IM45_960 3103241518f872006ed955d7420869e9 334 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 211 321 2.9E-33 T 12-10-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_960 3103241518f872006ed955d7420869e9 334 Gene3D G3DSA:3.40.50.300 1 166 5.5E-43 T 12-10-2018 IM45_960 3103241518f872006ed955d7420869e9 334 SUPERFAMILY SSF48019 210 324 2.38E-26 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 IM45_757 705a790ca190ab15a055a11889c82d42 92 Pfam PF00203 Ribosomal protein S19 3 83 4.7E-35 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 Gene3D G3DSA:3.30.860.10 1 92 1.9E-42 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 SUPERFAMILY SSF54570 3 84 1.12E-34 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.221 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 1.8E-45 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 IM45_757 705a790ca190ab15a055a11889c82d42 92 PIRSF PIRSF002144 1 92 1.5E-32 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.1E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.1E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_757 705a790ca190ab15a055a11889c82d42 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.1E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_1057 4d3e28d0a8be4b685855ceced8dd5a68 82 SUPERFAMILY SSF111148 2 79 3.66E-34 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 IM45_1057 4d3e28d0a8be4b685855ceced8dd5a68 82 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 2 76 3.0E-27 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 IM45_1057 4d3e28d0a8be4b685855ceced8dd5a68 82 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 2 82 21.712 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 IM45_1057 4d3e28d0a8be4b685855ceced8dd5a68 82 Gene3D G3DSA:1.10.3880.10 2 76 2.1E-32 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 IM45_1057 4d3e28d0a8be4b685855ceced8dd5a68 82 Pfam PF04362 Bacterial Fe(2+) trafficking 2 79 1.8E-33 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 IM45_1057 4d3e28d0a8be4b685855ceced8dd5a68 82 PIRSF PIRSF029827 2 81 1.7E-38 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 Pfam PF04715 Anthranilate synthase component I, N terminal region 16 152 1.3E-28 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 105 450 2.1E-119 T 12-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 SUPERFAMILY SSF56322 5 456 7.85E-137 T 12-10-2018 IPR005801 ADC synthase GO:0009058 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 Pfam PF00425 chorismate binding enzyme 188 447 3.5E-85 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal IM45_1006 4a96f7cdba64078650da56932cd3d995 460 PRINTS PR00095 Anthranilate synthase component I signature 404 418 9.9E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 PRINTS PR00095 Anthranilate synthase component I signature 295 308 9.9E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 PRINTS PR00095 Anthranilate synthase component I signature 389 403 9.9E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 PRINTS PR00095 Anthranilate synthase component I signature 309 322 9.9E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 IM45_1006 4a96f7cdba64078650da56932cd3d995 460 Gene3D G3DSA:3.60.120.10 1 457 4.2E-161 T 12-10-2018 IPR005801 ADC synthase GO:0009058 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 Gene3D G3DSA:3.40.430.10 1 162 5.7E-50 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 SUPERFAMILY SSF53597 1 162 1.06E-51 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 Pfam PF00186 Dihydrofolate reductase 3 161 1.3E-50 T 12-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.3E-11 T 12-10-2018 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.3E-11 T 12-10-2018 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.3E-11 T 12-10-2018 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 PRINTS PR00070 Dihydrofolate reductase signature 93 107 1.3E-11 T 12-10-2018 IM45_1235 55f138dae8bd5f6a48cf4b94736a42dd 162 PIRSF PIRSF000194 1 162 9.8E-50 T 12-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 IM45_236 56fdffdbb924720bf1c459340b79755f 175 ProSitePatterns PS01068 OmpA-like domain. 103 147 - T 12-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 IM45_236 56fdffdbb924720bf1c459340b79755f 175 Pfam PF00691 OmpA family 70 165 9.1E-19 T 12-10-2018 IPR006665 OmpA-like domain IM45_236 56fdffdbb924720bf1c459340b79755f 175 PRINTS PR01021 OMPA domain signature 101 116 9.3E-14 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 IM45_236 56fdffdbb924720bf1c459340b79755f 175 PRINTS PR01021 OMPA domain signature 71 93 9.3E-14 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 IM45_236 56fdffdbb924720bf1c459340b79755f 175 PRINTS PR01021 OMPA domain signature 116 132 9.3E-14 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 IM45_236 56fdffdbb924720bf1c459340b79755f 175 Gene3D G3DSA:3.30.1330.60 41 171 8.8E-38 T 12-10-2018 IPR036737 OmpA-like domain superfamily IM45_236 56fdffdbb924720bf1c459340b79755f 175 SUPERFAMILY SSF103088 55 170 3.53E-31 T 12-10-2018 IPR036737 OmpA-like domain superfamily IM45_236 56fdffdbb924720bf1c459340b79755f 175 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 69 171 1.4E-40 T 12-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 IM45_236 56fdffdbb924720bf1c459340b79755f 175 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 5 171 27.916 T 12-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 IM45_556 bcc5d5c0b3b05cdbe6c6aff7ee32bdca 328 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 324 1.2E-71 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller IM45_556 bcc5d5c0b3b05cdbe6c6aff7ee32bdca 328 SUPERFAMILY SSF50974 19 325 3.92E-42 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 IM45_556 bcc5d5c0b3b05cdbe6c6aff7ee32bdca 328 Gene3D G3DSA:2.130.10.10 1 327 3.3E-99 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 PRINTS PR00973 Ribosomal protein S17 family signature 66 73 6.2E-14 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 PRINTS PR00973 Ribosomal protein S17 family signature 24 47 6.2E-14 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 PRINTS PR00973 Ribosomal protein S17 family signature 56 66 6.2E-14 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 Pfam PF00366 Ribosomal protein S17 10 76 6.1E-31 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 75 4.2E-34 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 80 23.51 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 76 3.0E-28 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 Gene3D G3DSA:2.40.50.140 1 84 9.3E-36 T 12-10-2018 IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 SUPERFAMILY SSF50249 5 81 2.36E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_767 8f6db5d4e0839b439e014338f43e7f88 85 ProSitePatterns PS00056 Ribosomal protein S17 signature. 56 68 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 TIGRFAM TIGR01933 hflK: HflK protein 73 333 1.0E-120 T 12-10-2018 IPR010201 HflK GO:0016021 IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 SUPERFAMILY SSF117892 114 235 1.96E-19 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 PRINTS PR00721 Stomatin signature 78 100 3.2E-7 T 12-10-2018 IPR001972 Stomatin family GO:0016020 IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 PRINTS PR00721 Stomatin signature 125 146 3.2E-7 T 12-10-2018 IPR001972 Stomatin family GO:0016020 IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 PRINTS PR00721 Stomatin signature 160 177 3.2E-7 T 12-10-2018 IPR001972 Stomatin family GO:0016020 IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 Gene3D G3DSA:3.30.479.30 101 233 8.5E-18 T 12-10-2018 IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 SMART SM00244 71 231 5.7E-39 T 12-10-2018 IPR001107 Band 7 domain IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 Pfam PF01145 SPFH domain / Band 7 family 75 247 1.0E-27 T 12-10-2018 IPR001107 Band 7 domain IM45_1275 a5604c5a5a609dcd970387e9480264ea 387 Pfam PF12221 Bacterial membrane protein N terminal 1 46 1.0E-11 T 12-10-2018 IPR020980 Menbrane protein HflK, N-terminal IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 Gene3D G3DSA:3.40.50.10930 4 299 1.7E-112 T 12-10-2018 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 Gene3D G3DSA:3.40.50.300 319 793 3.7E-185 T 12-10-2018 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 Gene3D G3DSA:1.10.486.10 439 649 3.7E-185 T 12-10-2018 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 792 5.0E-284 T 12-10-2018 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1114 20.241 T 12-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 PIRSF PIRSF000980 1 1114 0.0 T 12-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 Gene3D G3DSA:1.10.10.990 855 924 9.7E-23 T 12-10-2018 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 SUPERFAMILY SSF52540 1 329 1.18E-110 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 Gene3D G3DSA:1.10.10.160 79 187 1.7E-112 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1077 0.0 T 12-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 SUPERFAMILY SSF52540 351 797 5.84E-95 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1205 c2e5b0e1f816cdb98eff6bbaa114fe8c 1124 SUPERFAMILY SSF52980 809 1109 4.5E-86 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 Gene3D G3DSA:3.90.170.10 267 432 8.8E-68 T 12-10-2018 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 Gene3D G3DSA:3.40.440.10 6 248 1.8E-99 T 12-10-2018 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 SMART SM00788 4 425 1.9E-280 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 SUPERFAMILY SSF52540 3 430 3.4E-172 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 429 6.1E-191 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 434 203.434 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 Gene3D G3DSA:1.10.300.10 102 201 1.8E-99 T 12-10-2018 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 IM45_1271 b249473eb7590c90bda8f1b93c61ff83 434 Pfam PF00709 Adenylosuccinate synthetase 5 424 5.3E-171 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 IM45_266 edf1543f14a988bd516ada5b36b220db 698 SUPERFAMILY SSF52540 293 654 1.98E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_266 edf1543f14a988bd516ada5b36b220db 698 SMART SM00490 508 592 2.9E-20 T 12-10-2018 IPR001650 Helicase, C-terminal IM45_266 edf1543f14a988bd516ada5b36b220db 698 Gene3D G3DSA:3.40.50.300 211 453 1.5E-82 T 12-10-2018 IM45_266 edf1543f14a988bd516ada5b36b220db 698 SUPERFAMILY SSF52540 211 456 3.82E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_266 edf1543f14a988bd516ada5b36b220db 698 SMART SM00487 268 462 3.7E-33 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain IM45_266 edf1543f14a988bd516ada5b36b220db 698 Pfam PF00271 Helicase conserved C-terminal domain 483 591 4.3E-17 T 12-10-2018 IPR001650 Helicase, C-terminal IM45_266 edf1543f14a988bd516ada5b36b220db 698 Pfam PF00270 DEAD/DEAH box helicase 296 437 2.0E-20 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 IM45_266 edf1543f14a988bd516ada5b36b220db 698 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 29 665 9.3E-227 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 IM45_266 edf1543f14a988bd516ada5b36b220db 698 Gene3D G3DSA:2.40.50.140 48 143 6.6E-14 T 12-10-2018 IM45_266 edf1543f14a988bd516ada5b36b220db 698 Gene3D G3DSA:3.40.50.300 460 633 8.3E-48 T 12-10-2018 IM45_266 edf1543f14a988bd516ada5b36b220db 698 SUPERFAMILY SSF50249 9 178 1.63E-37 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_266 edf1543f14a988bd516ada5b36b220db 698 Pfam PF17191 RecG wedge domain 16 175 5.8E-16 T 12-10-2018 IPR033454 RecG, wedge domain IM45_948 f4d999344cd0210a8d736fbb3fa2aa9a 393 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 1 392 1.3E-138 T 12-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 IM45_948 f4d999344cd0210a8d736fbb3fa2aa9a 393 Pfam PF02687 FtsX-like permease family 280 386 1.1E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 IM45_948 f4d999344cd0210a8d736fbb3fa2aa9a 393 Pfam PF12704 MacB-like periplasmic core domain 6 220 1.1E-15 T 12-10-2018 IPR025857 MacB-like periplasmic core domain IM45_948 f4d999344cd0210a8d736fbb3fa2aa9a 393 TIGRFAM TIGR02213 lolE_release: lipoprotein releasing system, transmembrane protein LolE 1 391 2.3E-173 T 12-10-2018 IPR011926 Lipoprotein-releasing system transmembrane protein LolC/E, gammaproteobacteria type GO:0016021|GO:0042953|GO:0042954|GO:0044874 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 Gene3D G3DSA:1.10.286.10 1 84 7.7E-30 T 12-10-2018 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 Pfam PF01227 GTP cyclohydrolase I 38 216 3.5E-61 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 38 218 2.4E-79 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 96 112 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 SUPERFAMILY SSF55620 29 218 5.63E-70 T 12-10-2018 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 34 217 32.226 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 Gene3D G3DSA:3.30.1130.10 85 220 9.2E-52 T 12-10-2018 IM45_884 a41b3d8252184a06d7ec6bce1e009b53 220 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 144 154 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 IM45_1283 0a956645d924b429f86938625fbf2a27 159 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 129 1.4E-36 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 IM45_1283 0a956645d924b429f86938625fbf2a27 159 Gene3D G3DSA:3.40.50.300 1 153 1.0E-41 T 12-10-2018 IM45_1283 0a956645d924b429f86938625fbf2a27 159 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 139 1.1E-45 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 IM45_1283 0a956645d924b429f86938625fbf2a27 159 SUPERFAMILY SSF52540 27 134 3.72E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_414 5f3eb0c5bed6c7254bef122c956e5447 407 SUPERFAMILY SSF52507 4 177 2.22E-55 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 IM45_414 5f3eb0c5bed6c7254bef122c956e5447 407 Gene3D G3DSA:3.40.50.10300 184 407 1.2E-80 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 IM45_414 5f3eb0c5bed6c7254bef122c956e5447 407 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 189 372 8.6E-69 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 IM45_414 5f3eb0c5bed6c7254bef122c956e5447 407 Gene3D G3DSA:3.40.50.1950 1 183 1.1E-51 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 IM45_414 5f3eb0c5bed6c7254bef122c956e5447 407 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 5 398 1.2E-146 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 IM45_414 5f3eb0c5bed6c7254bef122c956e5447 407 SUPERFAMILY SSF102645 187 403 1.11E-75 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 IM45_414 5f3eb0c5bed6c7254bef122c956e5447 407 Pfam PF02441 Flavoprotein 7 177 1.2E-41 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 IM45_099 face25755b395d62505bbab292852d88 92 SMART SM00411 1 90 6.3E-39 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_099 face25755b395d62505bbab292852d88 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.4E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_099 face25755b395d62505bbab292852d88 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.4E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_099 face25755b395d62505bbab292852d88 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.4E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_099 face25755b395d62505bbab292852d88 92 Gene3D G3DSA:4.10.520.10 1 90 6.5E-35 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 IM45_099 face25755b395d62505bbab292852d88 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 IM45_099 face25755b395d62505bbab292852d88 92 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.2E-30 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_099 face25755b395d62505bbab292852d88 92 SUPERFAMILY SSF47729 1 90 3.68E-31 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 IM45_145 ca74ac8df670cda765279acff5e4439d 493 SUPERFAMILY SSF50475 3 322 6.28E-120 T 12-10-2018 IM45_145 ca74ac8df670cda765279acff5e4439d 493 Gene3D G3DSA:1.20.5.570 455 493 3.5E-17 T 12-10-2018 IM45_145 ca74ac8df670cda765279acff5e4439d 493 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 70.958 T 12-10-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 IM45_145 ca74ac8df670cda765279acff5e4439d 493 Gene3D G3DSA:3.40.1670.10 337 454 1.6E-50 T 12-10-2018 IM45_145 ca74ac8df670cda765279acff5e4439d 493 SUPERFAMILY SSF143968 324 486 3.27E-64 T 12-10-2018 IM45_145 ca74ac8df670cda765279acff5e4439d 493 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 1.3E-174 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 IM45_145 ca74ac8df670cda765279acff5e4439d 493 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 431 6.1E-163 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 IM45_234 5d92976f0bd8879954985d28be6efdd9 434 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 4 430 45.708 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 IM45_234 5d92976f0bd8879954985d28be6efdd9 434 Pfam PF07676 WD40-like Beta Propeller Repeat 238 273 4.8E-11 T 12-10-2018 IPR011659 WD40-like Beta Propeller IM45_234 5d92976f0bd8879954985d28be6efdd9 434 Pfam PF07676 WD40-like Beta Propeller Repeat 372 403 0.054 T 12-10-2018 IPR011659 WD40-like Beta Propeller IM45_234 5d92976f0bd8879954985d28be6efdd9 434 Pfam PF07676 WD40-like Beta Propeller Repeat 283 316 8.3E-9 T 12-10-2018 IPR011659 WD40-like Beta Propeller IM45_234 5d92976f0bd8879954985d28be6efdd9 434 Gene3D G3DSA:2.120.10.30 165 434 9.2E-98 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like IM45_234 5d92976f0bd8879954985d28be6efdd9 434 Gene3D G3DSA:3.40.50.10070 22 164 3.8E-50 T 12-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 IM45_234 5d92976f0bd8879954985d28be6efdd9 434 SUPERFAMILY SSF52964 28 161 1.44E-37 T 12-10-2018 IM45_234 5d92976f0bd8879954985d28be6efdd9 434 SUPERFAMILY SSF69304 155 432 1.83E-51 T 12-10-2018 IM45_234 5d92976f0bd8879954985d28be6efdd9 434 Pfam PF04052 TolB amino-terminal domain 23 123 6.7E-29 T 12-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 IM45_234 5d92976f0bd8879954985d28be6efdd9 434 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 14 431 1.3E-148 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 IM45_785 467523ecfdc7719cc5c63bcdbe3c6d7c 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 5.2E-24 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_785 467523ecfdc7719cc5c63bcdbe3c6d7c 59 SUPERFAMILY SSF55129 3 58 6.28E-20 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily IM45_785 467523ecfdc7719cc5c63bcdbe3c6d7c 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 20.126 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_785 467523ecfdc7719cc5c63bcdbe3c6d7c 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 12-10-2018 IPR018038 Ribosomal protein L30, conserved site IM45_785 467523ecfdc7719cc5c63bcdbe3c6d7c 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 3.3E-17 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain IM45_785 467523ecfdc7719cc5c63bcdbe3c6d7c 59 PIRSF PIRSF002211 1 59 6.6E-27 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_785 467523ecfdc7719cc5c63bcdbe3c6d7c 59 Gene3D G3DSA:3.30.1390.20 1 58 6.0E-24 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily IM45_276 75a1836a90c704f47d23e23154fa5f75 632 Hamap MF_00505 Chaperone protein HtpG [htpG]. 4 624 31.11 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 IM45_276 75a1836a90c704f47d23e23154fa5f75 632 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 184 7.3E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase IM45_276 75a1836a90c704f47d23e23154fa5f75 632 SUPERFAMILY SSF110942 511 623 6.93E-32 T 12-10-2018 IPR037196 HSP90, C-terminal domain IM45_276 75a1836a90c704f47d23e23154fa5f75 632 SMART SM00387 29 186 1.2E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PRINTS PR00775 90kDa heat shock protein signature 122 144 2.6E-63 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PRINTS PR00775 90kDa heat shock protein signature 192 210 2.6E-63 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PRINTS PR00775 90kDa heat shock protein signature 7 27 2.6E-63 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PRINTS PR00775 90kDa heat shock protein signature 28 50 2.6E-63 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PRINTS PR00775 90kDa heat shock protein signature 77 94 2.6E-63 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PRINTS PR00775 90kDa heat shock protein signature 95 112 2.6E-63 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PRINTS PR00775 90kDa heat shock protein signature 174 191 2.6E-63 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal IM45_276 75a1836a90c704f47d23e23154fa5f75 632 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 27 36 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 IM45_276 75a1836a90c704f47d23e23154fa5f75 632 SUPERFAMILY SSF55874 7 215 2.75E-63 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily IM45_276 75a1836a90c704f47d23e23154fa5f75 632 SUPERFAMILY SSF54211 231 486 4.48E-91 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_276 75a1836a90c704f47d23e23154fa5f75 632 Gene3D G3DSA:3.40.50.11260 403 494 3.8E-30 T 12-10-2018 IM45_276 75a1836a90c704f47d23e23154fa5f75 632 Gene3D G3DSA:3.30.565.10 2 217 1.4E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily IM45_276 75a1836a90c704f47d23e23154fa5f75 632 Gene3D G3DSA:3.30.230.80 230 402 1.3E-65 T 12-10-2018 IM45_276 75a1836a90c704f47d23e23154fa5f75 632 PIRSF PIRSF002583 1 629 9.1E-203 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 IM45_276 75a1836a90c704f47d23e23154fa5f75 632 Pfam PF00183 Hsp90 protein 216 624 8.5E-117 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 IM45_276 75a1836a90c704f47d23e23154fa5f75 632 Gene3D G3DSA:1.20.120.790 495 624 1.8E-39 T 12-10-2018 IPR037196 HSP90, C-terminal domain IM45_1295 f964918cb47817dd71c67f4414330ed5 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 Gene3D G3DSA:1.10.560.10 8 521 1.6E-236 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily IM45_1295 f964918cb47817dd71c67f4414330ed5 547 SUPERFAMILY SSF48592 7 521 5.08E-76 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily IM45_1295 f964918cb47817dd71c67f4414330ed5 547 Gene3D G3DSA:3.30.260.10 136 410 1.6E-236 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily IM45_1295 f964918cb47817dd71c67f4414330ed5 547 PRINTS PR00298 60kDa chaperonin signature 27 53 2.8E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 PRINTS PR00298 60kDa chaperonin signature 350 375 2.8E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 PRINTS PR00298 60kDa chaperonin signature 398 419 2.8E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 PRINTS PR00298 60kDa chaperonin signature 83 110 2.8E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 PRINTS PR00298 60kDa chaperonin signature 268 291 2.8E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 SUPERFAMILY SSF52029 185 376 6.28E-81 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily IM45_1295 f964918cb47817dd71c67f4414330ed5 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 5.9E-254 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 Gene3D G3DSA:3.50.7.10 192 372 1.6E-236 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily IM45_1295 f964918cb47817dd71c67f4414330ed5 547 Hamap MF_00600 60 kDa chaperonin [groL]. 2 546 41.082 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 3.6E-92 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 IM45_1295 f964918cb47817dd71c67f4414330ed5 547 SUPERFAMILY SSF54849 137 204 4.58E-24 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily IM45_288 2586b004f72a539efbd145f004c15405 295 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 283 3.2E-65 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 SUPERFAMILY SSF51735 125 282 6.36E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_288 2586b004f72a539efbd145f004c15405 295 Gene3D G3DSA:3.40.50.10860 10 278 9.0E-101 T 12-10-2018 IM45_288 2586b004f72a539efbd145f004c15405 295 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 7 123 2.2E-35 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 78 103 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 Hamap MF_01576 Bifunctional protein FolD [folD]. 5 285 36.416 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 Gene3D G3DSA:3.40.50.720 8 261 9.0E-101 T 12-10-2018 IM45_288 2586b004f72a539efbd145f004c15405 295 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 262 270 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 SUPERFAMILY SSF53223 5 124 1.92E-37 T 12-10-2018 IM45_288 2586b004f72a539efbd145f004c15405 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 157 177 1.7E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 241 257 1.7E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 36 58 1.7E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 1.7E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 77 104 1.7E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 112 133 1.7E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_288 2586b004f72a539efbd145f004c15405 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 206 235 1.7E-81 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Pfam PF07517 SecA DEAD-like domain 7 402 2.6E-128 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 830 19.56 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Pfam PF01043 SecA preprotein cross-linking domain 232 358 1.9E-36 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Pfam PF07516 SecA Wing and Scaffold domain 619 827 5.2E-65 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 SUPERFAMILY SSF52540 6 415 1.83E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 SUPERFAMILY SSF81886 622 833 2.22E-71 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 ProSitePatterns PS01312 SecA family signature. 500 515 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Gene3D G3DSA:1.10.3060.10 623 831 8.1E-72 T 12-10-2018 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 SUPERFAMILY SSF52540 417 620 1.24E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 SMART SM00957 6 402 1.1E-289 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 SMART SM00958 228 358 3.9E-75 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 PRINTS PR00906 SecA protein signature 117 127 2.3E-73 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 PRINTS PR00906 SecA protein signature 170 190 2.3E-73 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 PRINTS PR00906 SecA protein signature 339 361 2.3E-73 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 PRINTS PR00906 SecA protein signature 413 426 2.3E-73 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 PRINTS PR00906 SecA protein signature 101 115 2.3E-73 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 PRINTS PR00906 SecA protein signature 376 393 2.3E-73 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 PRINTS PR00906 SecA protein signature 63 87 2.3E-73 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 815 0.0 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Gene3D G3DSA:3.40.50.300 22 415 1.3E-169 T 12-10-2018 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Gene3D G3DSA:3.40.50.300 417 622 1.3E-86 T 12-10-2018 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 Gene3D G3DSA:3.90.1440.10 229 368 1.3E-169 T 12-10-2018 IM45_1127 1994d2e5172e23f3188a17400593a5bd 842 SUPERFAMILY SSF81767 227 368 3.79E-41 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 153 163 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 224 277 3.1E-9 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 SUPERFAMILY SSF50692 819 895 1.47E-8 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 Gene3D G3DSA:2.20.25.90 224 277 2.5E-12 T 12-10-2018 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 106 118 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 Gene3D G3DSA:3.10.20.740 4 131 1.3E-28 T 12-10-2018 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 Gene3D G3DSA:3.40.50.740 510 695 9.0E-10 T 12-10-2018 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 91 125 3.3E-15 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 7 658 2.1E-203 T 12-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 SMART SM00926 224 278 4.3E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 81 8.5E-12 T 12-10-2018 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 SUPERFAMILY SSF54292 4 80 5.82E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 34 51 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 SMART SM00929 91 131 2.2E-18 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 SUPERFAMILY SSF54862 84 216 4.6E-34 T 12-10-2018 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 Pfam PF00384 Molybdopterin oxidoreductase 555 640 7.0E-6 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_845 020be201901f74fbe3580cf7d6ce8e74 912 SUPERFAMILY SSF53706 222 689 2.06E-82 T 12-10-2018 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Pfam PF02769 AIR synthase related protein, C-terminal domain 837 963 1.1E-10 T 12-10-2018 IPR010918 PurM-like, C-terminal domain IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Pfam PF02769 AIR synthase related protein, C-terminal domain 435 589 2.5E-26 T 12-10-2018 IPR010918 PurM-like, C-terminal domain IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SUPERFAMILY SSF52317 1039 1294 4.38E-92 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SUPERFAMILY SSF109736 157 219 1.31E-16 T 12-10-2018 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SUPERFAMILY SSF55326 621 816 3.14E-62 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Gene3D G3DSA:3.90.650.10 421 606 2.1E-51 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Gene3D G3DSA:3.90.650.10 808 981 1.1E-26 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SUPERFAMILY SSF82697 1 151 1.94E-43 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Gene3D G3DSA:1.10.8.750 153 213 6.7E-20 T 12-10-2018 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1041 1293 4.2E-99 T 12-10-2018 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1296 20.401 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 4 1294 0.0 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Gene3D G3DSA:3.40.50.880 982 1296 6.2E-132 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SUPERFAMILY SSF56042 822 1034 1.64E-49 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Gene3D G3DSA:3.30.1330.10 214 420 1.3E-41 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SUPERFAMILY SSF56042 434 615 1.79E-49 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SMART SM01211 1040 1295 2.7E-141 T 12-10-2018 IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 Gene3D G3DSA:3.30.1330.10 617 807 5.3E-21 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_005 d80ca8eeae45690f6470075b4cb43eff 1296 SUPERFAMILY SSF55326 221 428 1.36E-63 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_147 76bb12de64d6196dd829793b24726abb 248 SUPERFAMILY SSF52343 115 246 5.63E-32 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain IM45_147 76bb12de64d6196dd829793b24726abb 248 Gene3D G3DSA:2.40.30.10 17 113 1.8E-22 T 12-10-2018 IM45_147 76bb12de64d6196dd829793b24726abb 248 SUPERFAMILY SSF63380 18 112 2.51E-18 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel IM45_147 76bb12de64d6196dd829793b24726abb 248 Gene3D G3DSA:3.40.50.80 114 248 6.8E-26 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain IM45_147 76bb12de64d6196dd829793b24726abb 248 Pfam PF00175 Oxidoreductase NAD-binding domain 123 226 7.1E-19 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 IM45_147 76bb12de64d6196dd829793b24726abb 248 PRINTS PR00410 Phenol hydroxylase reductase family signature 122 141 8.6E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 IM45_147 76bb12de64d6196dd829793b24726abb 248 PRINTS PR00410 Phenol hydroxylase reductase family signature 106 115 8.6E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 IM45_147 76bb12de64d6196dd829793b24726abb 248 PRINTS PR00410 Phenol hydroxylase reductase family signature 147 156 8.6E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 IM45_147 76bb12de64d6196dd829793b24726abb 248 PRINTS PR00410 Phenol hydroxylase reductase family signature 46 58 8.6E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 IM45_387 b60c61c5b685d6d832790df81a39af2b 271 Gene3D G3DSA:1.10.3130.10 1 142 1.0E-49 T 12-10-2018 IM45_387 b60c61c5b685d6d832790df81a39af2b 271 Gene3D G3DSA:2.160.10.10 143 264 5.1E-38 T 12-10-2018 IM45_387 b60c61c5b685d6d832790df81a39af2b 271 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 IM45_387 b60c61c5b685d6d832790df81a39af2b 271 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 193 227 2.2E-9 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_387 b60c61c5b685d6d832790df81a39af2b 271 SUPERFAMILY SSF51161 7 259 1.18E-65 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily IM45_387 b60c61c5b685d6d832790df81a39af2b 271 PIRSF PIRSF000441 75 261 1.6E-58 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 IM45_387 b60c61c5b685d6d832790df81a39af2b 271 Pfam PF06426 Serine acetyltransferase, N-terminal 9 113 4.5E-36 T 12-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 IM45_387 b60c61c5b685d6d832790df81a39af2b 271 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 83 242 3.9E-72 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 IM45_387 b60c61c5b685d6d832790df81a39af2b 271 SMART SM00971 9 113 7.5E-58 T 12-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 Gene3D G3DSA:1.10.8.630 2 113 3.1E-31 T 12-10-2018 IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 Pfam PF00271 Helicase conserved C-terminal domain 524 591 1.3E-5 T 12-10-2018 IPR001650 Helicase, C-terminal IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 SMART SM00490 494 591 8.5E-9 T 12-10-2018 IPR001650 Helicase, C-terminal IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 Hamap MF_00983 Probable primosomal protein N' [priA]. 6 734 24.797 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 SUPERFAMILY SSF52540 218 602 4.5E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 Gene3D G3DSA:3.40.50.300 185 381 7.8E-77 T 12-10-2018 IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 SMART SM00487 197 393 1.6E-16 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 TIGRFAM TIGR00595 priA: primosomal protein N' 223 732 3.9E-196 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 IM45_374 c7843ca256ff9fb72f12c86ce53ea1dd 734 Pfam PF00270 DEAD/DEAH box helicase 220 365 2.8E-13 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 IM45_835 c992432f09f7c9c09a11046f533148f8 508 Pfam PF00361 Proton-conducting membrane transporter 134 430 8.0E-62 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_835 c992432f09f7c9c09a11046f533148f8 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 249 273 1.9E-35 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_835 c992432f09f7c9c09a11046f533148f8 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 389 415 1.9E-35 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_835 c992432f09f7c9c09a11046f533148f8 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 1.9E-35 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_835 c992432f09f7c9c09a11046f533148f8 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 1.9E-35 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_835 c992432f09f7c9c09a11046f533148f8 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 337 356 1.9E-35 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_835 c992432f09f7c9c09a11046f533148f8 508 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 3 495 5.9E-166 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_702 a0934546c3148c72aa78a78a9b410cd7 135 Gene3D G3DSA:1.10.287.1050 1 83 3.0E-35 T 12-10-2018 IPR027454 Histone-like protein H-NS, N-terminal GO:0046983 IM45_702 a0934546c3148c72aa78a78a9b410cd7 135 SUPERFAMILY SSF81273 93 135 4.71E-11 T 12-10-2018 IM45_702 a0934546c3148c72aa78a78a9b410cd7 135 Pfam PF00816 H-NS histone family 32 126 8.8E-19 T 12-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 IM45_702 a0934546c3148c72aa78a78a9b410cd7 135 Gene3D G3DSA:4.10.430.10 91 135 2.1E-23 T 12-10-2018 IPR037150 Histone-like protein H-NS, C-terminal domain superfamily GO:0003677 IM45_702 a0934546c3148c72aa78a78a9b410cd7 135 SMART SM00528 87 135 3.2E-20 T 12-10-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 IM45_702 a0934546c3148c72aa78a78a9b410cd7 135 SUPERFAMILY SSF81273 2 58 8.24E-18 T 12-10-2018 IM45_702 a0934546c3148c72aa78a78a9b410cd7 135 PIRSF PIRSF002096 1 135 4.8E-54 T 12-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 IM45_933 ff4d445eaa00cdae06e694e21ffc0fa8 225 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 2 224 2.5E-72 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 IM45_933 ff4d445eaa00cdae06e694e21ffc0fa8 225 SUPERFAMILY SSF51735 56 220 3.63E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_933 ff4d445eaa00cdae06e694e21ffc0fa8 225 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 72 145 2.3E-11 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase IM45_933 ff4d445eaa00cdae06e694e21ffc0fa8 225 Gene3D G3DSA:3.40.50.10860 2 208 3.0E-66 T 12-10-2018 IM45_933 ff4d445eaa00cdae06e694e21ffc0fa8 225 SUPERFAMILY SSF53223 2 55 9.78E-14 T 12-10-2018 IM45_933 ff4d445eaa00cdae06e694e21ffc0fa8 225 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 2 42 8.3E-10 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 IM45_933 ff4d445eaa00cdae06e694e21ffc0fa8 225 Gene3D G3DSA:3.40.50.720 56 198 3.0E-66 T 12-10-2018 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 636 2.1E-214 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Hamap MF_02004 Valine--tRNA ligase [valS]. 7 955 15.651 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 SUPERFAMILY SSF50677 197 370 1.57E-50 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 PRINTS PR00986 Valyl-tRNA synthetase signature 41 52 7.0E-33 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 PRINTS PR00986 Valyl-tRNA synthetase signature 506 524 7.0E-33 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 PRINTS PR00986 Valyl-tRNA synthetase signature 475 496 7.0E-33 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 PRINTS PR00986 Valyl-tRNA synthetase signature 242 259 7.0E-33 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 PRINTS PR00986 Valyl-tRNA synthetase signature 375 388 7.0E-33 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Gene3D G3DSA:3.90.740.10 204 362 1.2E-40 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Gene3D G3DSA:1.10.730.10 639 822 1.3E-54 T 12-10-2018 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Gene3D G3DSA:1.10.287.380 883 952 4.3E-14 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 894 949 2.7E-11 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 SUPERFAMILY SSF52374 5 647 8.57E-137 T 12-10-2018 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 SUPERFAMILY SSF47323 648 902 4.3E-63 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Pfam PF08264 Anticodon-binding domain of tRNA 680 829 2.6E-41 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 SUPERFAMILY SSF46589 893 950 4.08E-10 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 IM45_652 2a8acde50471b281b5660dd295fbc77b 957 Gene3D G3DSA:3.40.50.620 8 203 2.5E-64 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_652 2a8acde50471b281b5660dd295fbc77b 957 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 937 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 745 756 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Gene3D G3DSA:3.40.50.970 793 1174 2.2E-139 T 12-10-2018 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Pfam PF10371 Domain of unknown function 628 678 8.5E-23 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 SUPERFAMILY SSF52518 795 1175 7.43E-109 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 SUPERFAMILY SSF52922 256 408 1.33E-37 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 958 1069 3.1E-7 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Gene3D G3DSA:3.40.920.10 417 622 1.4E-72 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 347 1.2E-13 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 SMART SM00890 622 679 3.1E-27 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 426 608 1.4E-30 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 PIRSF PIRSF000159 1 1179 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Gene3D G3DSA:3.40.50.970 1 254 3.8E-102 T 12-10-2018 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 SUPERFAMILY SSF53323 418 668 1.26E-71 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Gene3D G3DSA:4.10.780.10 633 668 2.0E-6 T 12-10-2018 IPR037112 Pyruvate-flavodoxin oxidoreductase, EKR domain superfamily IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Gene3D G3DSA:3.40.50.920 255 414 1.1E-51 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Gene3D G3DSA:3.30.70.20 669 791 9.5E-38 T 12-10-2018 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 13 244 1.1E-77 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 SUPERFAMILY SSF52518 2 254 8.83E-70 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 Pfam PF12838 4Fe-4S dicluster domain 689 757 4.6E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 1 1172 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 IM45_935 b5d8a9e3defa2f0e1089b363851a0ee1 1179 SUPERFAMILY SSF54862 665 837 3.63E-22 T 12-10-2018 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 Gene3D G3DSA:3.40.50.1980 39 237 6.2E-118 T 12-10-2018 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 Gene3D G3DSA:3.40.50.1980 239 354 6.2E-118 T 12-10-2018 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 41 431 3.5E-155 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 203 228 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 257 276 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 325 350 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 41 65 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 142 168 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 366 384 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 235 256 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 3.8E-95 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 SUPERFAMILY SSF53720 14 432 1.9E-79 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 235 267 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 Pfam PF00815 Histidinol dehydrogenase 34 432 5.7E-160 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 12 432 39.41 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_903 350993cc15cf2cc082fa21a686e31cc1 439 PIRSF PIRSF000099 2 435 2.2E-161 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 247 258 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 SUPERFAMILY SSF56762 220 595 2.88E-117 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 44 171 1.2E-40 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 100 161 2.0E-18 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 45 172 3.1E-38 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 11 595 69.897 T 12-10-2018 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 210 595 4.3E-172 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 206 595 41.759 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 Gene3D G3DSA:3.30.460.80 5 152 2.5E-30 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 SUPERFAMILY SSF143243 21 224 4.58E-58 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 Gene3D G3DSA:1.10.645.20 209 595 5.8E-141 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_853 12f6db14289aa93f3a1a283c20b6334b 595 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 324 595 8.0E-102 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_619 df2097bcdcafbc0a05a3b16f01e2d93f 204 SUPERFAMILY SSF81452 23 202 1.03E-54 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_619 df2097bcdcafbc0a05a3b16f01e2d93f 204 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 25 204 6.6E-85 T 12-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 IM45_619 df2097bcdcafbc0a05a3b16f01e2d93f 204 Pfam PF00510 Cytochrome c oxidase subunit III 26 202 4.1E-14 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_619 df2097bcdcafbc0a05a3b16f01e2d93f 204 Gene3D G3DSA:1.20.120.80 20 204 3.3E-54 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_1008 240b6df05ca7b147fdeae40368246124 311 Pfam PF12368 Rhodanase C-terminal 246 308 1.1E-16 T 12-10-2018 IPR022111 Rhodanase, C-terminal IM45_1008 240b6df05ca7b147fdeae40368246124 311 Pfam PF00581 Rhodanese-like domain 138 232 2.1E-12 T 12-10-2018 IPR001763 Rhodanese-like domain IM45_1008 240b6df05ca7b147fdeae40368246124 311 Hamap MF_00469 UPF0176 protein YceA [yceA]. 22 276 36.931 T 12-10-2018 IPR020936 Uncharacterised protein family UPF0176 IM45_1008 240b6df05ca7b147fdeae40368246124 311 Gene3D G3DSA:3.30.70.100 13 118 1.0E-15 T 12-10-2018 IM45_1008 240b6df05ca7b147fdeae40368246124 311 Gene3D G3DSA:3.40.250.10 124 279 3.7E-40 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily IM45_1008 240b6df05ca7b147fdeae40368246124 311 SUPERFAMILY SSF52821 114 256 6.94E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily IM45_1008 240b6df05ca7b147fdeae40368246124 311 SMART SM00450 136 237 2.0E-22 T 12-10-2018 IPR001763 Rhodanese-like domain IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 Gene3D G3DSA:3.30.1370.170 294 376 7.7E-27 T 12-10-2018 IPR038251 PdxB, dimerisation domain superfamily KEGG: 00750+1.1.1.290 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 Pfam PF11890 Domain of unknown function (DUF3410) 291 370 6.0E-25 T 12-10-2018 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00750+1.1.1.290 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 Gene3D G3DSA:3.40.50.720 3 278 9.8E-106 T 12-10-2018 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 240 8.1E-29 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 Gene3D G3DSA:3.40.50.720 92 258 9.8E-106 T 12-10-2018 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 SUPERFAMILY SSF51735 91 245 1.68E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 279 1.4E-14 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 358 46.007 T 12-10-2018 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00750+1.1.1.290 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 SUPERFAMILY SSF52283 5 130 1.87E-16 T 12-10-2018 IM45_817 e826577fc2db385b2bb3f34dbbe4a997 376 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 119 146 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 Pfam PF00575 S1 RNA binding domain 642 724 5.3E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 Pfam PF00773 RNB domain 260 585 6.4E-108 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 Pfam PF08206 Ribonuclease B OB domain 87 144 6.9E-18 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 SUPERFAMILY SSF50249 643 730 5.92E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 SUPERFAMILY SSF50249 187 643 2.29E-136 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 SMART SM00357 86 145 1.0E-8 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 SUPERFAMILY SSF50249 67 145 1.14E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 TIGRFAM TIGR02063 RNase_R: ribonuclease R 19 725 2.1E-262 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 71 725 8.7E-251 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 SMART SM00955 260 587 2.1E-176 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 Gene3D G3DSA:2.40.50.140 64 147 2.5E-14 T 12-10-2018 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 ProSitePatterns PS01175 Ribonuclease II family signature. 554 578 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 Pfam PF08461 Ribonuclease R winged-helix domain 23 84 8.4E-10 T 12-10-2018 IPR013668 Ribonuclease R winged-helix domain IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 Gene3D G3DSA:2.40.50.140 645 744 1.0E-20 T 12-10-2018 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 SMART SM00316 642 725 2.8E-12 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_1269 cc1596e926c11a0c6e642da868ea9a7d 747 Hamap MF_01895 Ribonuclease R [rnr]. 38 725 54.223 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Gene3D G3DSA:3.30.870.10 505 691 2.5E-69 T 12-10-2018 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Pfam PF13089 Polyphosphate kinase N-terminal domain 7 109 3.2E-28 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 PIRSF PIRSF015589 1 694 2.1E-226 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Pfam PF02503 Polyphosphate kinase middle domain 119 306 9.5E-38 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 SUPERFAMILY SSF56024 506 687 1.26E-65 T 12-10-2018 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 SUPERFAMILY SSF140356 3 105 1.96E-28 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 6 682 8.5E-234 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 SUPERFAMILY SSF143724 107 310 6.08E-48 T 12-10-2018 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 SUPERFAMILY SSF56024 324 502 2.73E-53 T 12-10-2018 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Pfam PF13090 Polyphosphate kinase C-terminal domain 336 681 1.5E-139 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Gene3D G3DSA:3.30.1840.10 110 309 7.1E-64 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Gene3D G3DSA:3.30.870.10 322 504 3.1E-71 T 12-10-2018 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Hamap MF_00347 Polyphosphate kinase [ppk]. 4 686 26.049 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 IM45_181 00b5a6bd3ea2ae2d2947331004361396 694 Gene3D G3DSA:1.20.58.310 9 109 3.3E-32 T 12-10-2018 IM45_982 95625d0c91b837dfc2a302f63e11ca18 349 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 7 347 2.2E-135 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_982 95625d0c91b837dfc2a302f63e11ca18 349 Pfam PF01979 Amidohydrolase family 15 307 1.2E-15 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 IM45_982 95625d0c91b837dfc2a302f63e11ca18 349 PIRSF PIRSF001237 4 349 6.1E-133 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_982 95625d0c91b837dfc2a302f63e11ca18 349 Hamap MF_00219 Dihydroorotase [pyrC]. 6 348 44.468 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_982 95625d0c91b837dfc2a302f63e11ca18 349 SUPERFAMILY SSF51556 7 347 1.32E-136 T 12-10-2018 IPR032466 Metal-dependent hydrolase IM45_982 95625d0c91b837dfc2a302f63e11ca18 349 ProSitePatterns PS00483 Dihydroorotase signature 2. 249 260 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 IM45_982 95625d0c91b837dfc2a302f63e11ca18 349 Gene3D G3DSA:3.20.20.140 7 348 2.1E-101 T 12-10-2018 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 4.9E-42 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 4.9E-42 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 4.9E-42 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 4.9E-42 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 4.9E-42 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 4.9E-42 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 Pfam PF00459 Inositol monophosphatase family 2 253 3.4E-50 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 Gene3D G3DSA:3.40.190.80 144 256 7.6E-33 T 12-10-2018 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 5.2E-24 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 5.2E-24 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 5.2E-24 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 5.2E-24 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 Gene3D G3DSA:3.30.540.10 1 140 5.9E-38 T 12-10-2018 IM45_009 b4ef725f29caef59c0c4c15db924fb6e 256 SUPERFAMILY SSF56655 1 254 1.44E-62 T 12-10-2018 IM45_498 63d922217330fd2915100f4b4387cf6c 304 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 29 259 1.0E-65 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 IM45_498 63d922217330fd2915100f4b4387cf6c 304 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 10 304 7.7E-164 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 IM45_498 63d922217330fd2915100f4b4387cf6c 304 Gene3D G3DSA:3.40.50.620 7 212 2.9E-63 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_498 63d922217330fd2915100f4b4387cf6c 304 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 4 304 57.09 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 IM45_498 63d922217330fd2915100f4b4387cf6c 304 PIRSF PIRSF002936 1 304 3.9E-152 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 IM45_498 63d922217330fd2915100f4b4387cf6c 304 SUPERFAMILY SSF52402 7 210 9.16E-73 T 12-10-2018 IM45_908 b966fc0b28c93c1f5556f74e0db625f4 276 SUPERFAMILY SSF51735 6 265 2.47E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_908 b966fc0b28c93c1f5556f74e0db625f4 276 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 69 2.7E-5 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 IM45_908 b966fc0b28c93c1f5556f74e0db625f4 276 Gene3D G3DSA:3.40.50.720 1 269 1.5E-48 T 12-10-2018 IM45_067 e83bc7c98f1ff41650f2359230b96597 196 Gene3D G3DSA:3.40.50.10490 2 196 1.6E-63 T 12-10-2018 IM45_067 e83bc7c98f1ff41650f2359230b96597 196 Pfam PF13580 SIS domain 9 144 3.4E-28 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 IM45_067 e83bc7c98f1ff41650f2359230b96597 196 SUPERFAMILY SSF53697 5 191 3.03E-45 T 12-10-2018 IM45_031 625a2395999f2e40e774b4dcd0afc771 181 SUPERFAMILY SSF55811 3 180 4.74E-35 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 IM45_031 625a2395999f2e40e774b4dcd0afc771 181 Gene3D G3DSA:3.90.79.10 8 181 1.2E-43 T 12-10-2018 IM45_031 625a2395999f2e40e774b4dcd0afc771 181 Pfam PF00293 NUDIX domain 48 124 1.4E-11 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 IM45_031 625a2395999f2e40e774b4dcd0afc771 181 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 1.3E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 1.3E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.3E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.3E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 2.5E-35 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 2.5E-35 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 2.5E-35 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 2.5E-35 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 2.5E-35 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 2.5E-35 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 5.9E-44 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 SUPERFAMILY SSF53671 3 307 1.87E-95 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 37.544 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 7.2E-114 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_595 59632a783e945630034dc1a90b893828 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 Gene3D G3DSA:3.40.50.1370 8 304 5.7E-116 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 303 1.9E-25 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 IM45_595 59632a783e945630034dc1a90b893828 311 Gene3D G3DSA:3.40.50.1370 135 292 5.7E-116 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 Gene3D G3DSA:3.40.190.10 160 263 1.1E-66 T 12-10-2018 IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.1E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 Gene3D G3DSA:1.10.10.10 1 89 1.8E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 Pfam PF03466 LysR substrate binding domain 85 288 1.5E-37 T 12-10-2018 IPR005119 LysR, substrate-binding IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 SUPERFAMILY SSF46785 1 109 3.33E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 SUPERFAMILY SSF53850 86 289 2.64E-37 T 12-10-2018 IM45_035 b6e9ad648ecb1fdae4b06135c497d6ce 303 Gene3D G3DSA:3.40.190.10 90 286 1.1E-66 T 12-10-2018 IM45_1251 96fd5dc319f17e41030a7b152a99daf3 144 Gene3D G3DSA:3.30.530.20 4 144 1.0E-37 T 12-10-2018 IPR023393 START-like domain superfamily IM45_1251 96fd5dc319f17e41030a7b152a99daf3 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 135 1.0E-28 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 IM45_1251 96fd5dc319f17e41030a7b152a99daf3 144 SUPERFAMILY SSF55961 1 143 1.3E-31 T 12-10-2018 IM45_1199 26ef979c17bbcd207f58d073d14b5a88 178 SUPERFAMILY SSF55811 4 153 2.3E-30 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 IM45_1199 26ef979c17bbcd207f58d073d14b5a88 178 Gene3D G3DSA:3.90.79.10 1 159 4.4E-49 T 12-10-2018 IM45_1199 26ef979c17bbcd207f58d073d14b5a88 178 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 IM45_1199 26ef979c17bbcd207f58d073d14b5a88 178 Pfam PF00293 NUDIX domain 7 146 5.2E-26 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 IM45_1199 26ef979c17bbcd207f58d073d14b5a88 178 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 36.692 T 12-10-2018 IPR022927 RNA pyrophosphohydrolase RppH IM45_1199 26ef979c17bbcd207f58d073d14b5a88 178 PRINTS PR00502 NUDIX hydrolase family signature 47 62 3.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 IM45_1199 26ef979c17bbcd207f58d073d14b5a88 178 PRINTS PR00502 NUDIX hydrolase family signature 33 47 3.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 PRINTS PR00773 GrpE protein signature 93 108 2.3E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 PRINTS PR00773 GrpE protein signature 175 194 2.3E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 PRINTS PR00773 GrpE protein signature 65 81 2.3E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 PRINTS PR00773 GrpE protein signature 148 163 2.3E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 Hamap MF_01151 Protein GrpE [grpE]. 4 196 21.322 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 Gene3D G3DSA:3.90.20.20 36 139 5.5E-34 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 ProSitePatterns PS01071 grpE protein signature. 151 194 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 SUPERFAMILY SSF51064 141 197 1.83E-17 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 Pfam PF01025 GrpE 33 196 1.1E-46 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 Gene3D G3DSA:2.30.22.10 140 196 6.0E-24 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 IM45_1340 f2bdb079cc2d7f0f122120800bce988c 199 SUPERFAMILY SSF58014 46 140 1.02E-25 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 IM45_115 41070edb93229db2e881aab497981c09 300 Gene3D G3DSA:2.40.10.350 162 239 2.2E-30 T 12-10-2018 IM45_115 41070edb93229db2e881aab497981c09 300 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 253 1.6E-96 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 IM45_115 41070edb93229db2e881aab497981c09 300 Gene3D G3DSA:2.40.10.340 104 248 2.2E-30 T 12-10-2018 IM45_115 41070edb93229db2e881aab497981c09 300 Pfam PF04085 rod shape-determining protein MreC 105 251 9.3E-34 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 IM45_115 41070edb93229db2e881aab497981c09 300 PIRSF PIRSF038471 1 256 7.1E-63 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 IM45_531 699415b92bbf4b9ad943f22eca4d54c5 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 280 2.0E-102 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 IM45_531 699415b92bbf4b9ad943f22eca4d54c5 283 Pfam PF02569 Pantoate-beta-alanine ligase 3 278 4.5E-97 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 IM45_531 699415b92bbf4b9ad943f22eca4d54c5 283 Gene3D G3DSA:3.40.50.620 1 179 5.9E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_531 699415b92bbf4b9ad943f22eca4d54c5 283 SUPERFAMILY SSF52374 2 281 2.38E-99 T 12-10-2018 IM45_531 699415b92bbf4b9ad943f22eca4d54c5 283 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 38.566 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 IM45_531 699415b92bbf4b9ad943f22eca4d54c5 283 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 24 69 1.4E-7 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 IM45_531 699415b92bbf4b9ad943f22eca4d54c5 283 Gene3D G3DSA:3.30.1300.10 180 282 2.3E-29 T 12-10-2018 IM45_1189 4c3c7b0ebd137eaf293de80cbcf658dc 157 SUPERFAMILY SSF51161 2 153 6.58E-44 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily IM45_1189 4c3c7b0ebd137eaf293de80cbcf658dc 157 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 1.4E-7 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_1189 4c3c7b0ebd137eaf293de80cbcf658dc 157 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 52 7.6E-8 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_1189 4c3c7b0ebd137eaf293de80cbcf658dc 157 Gene3D G3DSA:2.160.10.10 1 156 1.1E-37 T 12-10-2018 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 84 104 4.1E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 141 161 4.1E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 164 179 4.1E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 63 78 4.1E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 115 139 4.1E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 255 271 4.1E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 Gene3D G3DSA:3.30.930.10 2 216 1.9E-107 T 12-10-2018 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 SUPERFAMILY SSF55681 10 294 3.73E-126 T 12-10-2018 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 10 302 1.9E-162 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 9 295 60.094 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 Gene3D G3DSA:1.20.58.180 217 300 3.2E-30 T 12-10-2018 IM45_363 7150e8d4a8065c02a4d30eefad343fe5 307 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 11 293 3.5E-145 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 IM45_075 3804f03a860fe2697176066486ed089d 456 SMART SM00228 351 448 1.5E-5 T 12-10-2018 IPR001478 PDZ domain GO:0005515 IM45_075 3804f03a860fe2697176066486ed089d 456 SMART SM00228 268 350 3.2E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 IM45_075 3804f03a860fe2697176066486ed089d 456 PRINTS PR00834 HtrA/DegQ protease family signature 124 144 1.2E-56 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 IM45_075 3804f03a860fe2697176066486ed089d 456 PRINTS PR00834 HtrA/DegQ protease family signature 308 320 1.2E-56 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 IM45_075 3804f03a860fe2697176066486ed089d 456 PRINTS PR00834 HtrA/DegQ protease family signature 103 115 1.2E-56 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 IM45_075 3804f03a860fe2697176066486ed089d 456 PRINTS PR00834 HtrA/DegQ protease family signature 200 217 1.2E-56 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 IM45_075 3804f03a860fe2697176066486ed089d 456 PRINTS PR00834 HtrA/DegQ protease family signature 165 189 1.2E-56 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 IM45_075 3804f03a860fe2697176066486ed089d 456 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 1.2E-56 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 IM45_075 3804f03a860fe2697176066486ed089d 456 Pfam PF13365 Trypsin-like peptidase domain 93 229 2.6E-30 T 12-10-2018 IM45_075 3804f03a860fe2697176066486ed089d 456 Gene3D G3DSA:2.40.10.120 37 262 1.2E-82 T 12-10-2018 IM45_075 3804f03a860fe2697176066486ed089d 456 SUPERFAMILY SSF50156 267 360 6.66E-20 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 IM45_075 3804f03a860fe2697176066486ed089d 456 Gene3D G3DSA:2.30.42.10 263 364 1.1E-25 T 12-10-2018 IM45_075 3804f03a860fe2697176066486ed089d 456 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 39 454 1.5E-152 T 12-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 IM45_075 3804f03a860fe2697176066486ed089d 456 SUPERFAMILY SSF50494 18 277 1.19E-63 T 12-10-2018 IPR009003 Peptidase S1, PA clan IM45_075 3804f03a860fe2697176066486ed089d 456 Pfam PF13180 PDZ domain 269 358 1.4E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 IM45_075 3804f03a860fe2697176066486ed089d 456 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 377 444 9.6E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 IM45_075 3804f03a860fe2697176066486ed089d 456 Gene3D G3DSA:2.30.42.10 365 456 1.1E-19 T 12-10-2018 IM45_075 3804f03a860fe2697176066486ed089d 456 SUPERFAMILY SSF50156 387 452 4.73E-12 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 IM45_025 61358e8adb4ef3b673b12c90370dc370 757 Pfam PF07670 Nucleoside recognition 350 439 3.7E-11 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 IM45_025 61358e8adb4ef3b673b12c90370dc370 757 Pfam PF07670 Nucleoside recognition 513 694 1.2E-30 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 IM45_025 61358e8adb4ef3b673b12c90370dc370 757 Pfam PF07664 Ferrous iron transport protein B C terminus 454 505 5.9E-17 T 12-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 IM45_025 61358e8adb4ef3b673b12c90370dc370 757 Gene3D G3DSA:3.40.50.300 4 168 6.1E-37 T 12-10-2018 IM45_025 61358e8adb4ef3b673b12c90370dc370 757 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 11 692 4.8E-190 T 12-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 IM45_025 61358e8adb4ef3b673b12c90370dc370 757 SUPERFAMILY SSF52540 6 168 1.27E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_025 61358e8adb4ef3b673b12c90370dc370 757 Pfam PF02421 Ferrous iron transport protein B 6 162 5.3E-58 T 12-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 IM45_886 4329cd4d1c47fb041fd7a2441d8bc7cc 193 Pfam PF06559 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 3 161 4.3E-10 T 12-10-2018 IPR010550 Deoxycytidine triphosphate deaminase, bacterial GO:0008829|GO:0009394 IM45_886 4329cd4d1c47fb041fd7a2441d8bc7cc 193 SUPERFAMILY SSF51283 1 193 4.84E-57 T 12-10-2018 IPR036157 dUTPase-like superfamily IM45_886 4329cd4d1c47fb041fd7a2441d8bc7cc 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 190 31.969 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 IM45_886 4329cd4d1c47fb041fd7a2441d8bc7cc 193 Gene3D G3DSA:2.70.40.10 1 161 1.1E-48 T 12-10-2018 IPR036157 dUTPase-like superfamily IM45_886 4329cd4d1c47fb041fd7a2441d8bc7cc 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 190 8.8E-64 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 Gene3D G3DSA:3.40.50.300 73 297 6.2E-39 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 PRINTS PR01874 DNA repair protein radA signature 11 35 1.4E-86 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 PRINTS PR01874 DNA repair protein radA signature 221 249 1.4E-86 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 PRINTS PR01874 DNA repair protein radA signature 331 354 1.4E-86 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 PRINTS PR01874 DNA repair protein radA signature 182 206 1.4E-86 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 PRINTS PR01874 DNA repair protein radA signature 88 116 1.4E-86 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 PRINTS PR01874 DNA repair protein radA signature 256 282 1.4E-86 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 PRINTS PR01874 DNA repair protein radA signature 131 148 1.4E-86 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 Pfam PF13541 Subunit ChlI of Mg-chelatase 354 439 9.0E-10 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 SUPERFAMILY SSF54211 302 463 1.18E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 SUPERFAMILY SSF52540 74 296 1.8E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 Pfam PF13481 AAA domain 90 230 4.3E-16 T 12-10-2018 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 SMART SM00382 96 253 1.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 Hamap MF_01498 DNA repair protein RadA [radA]. 22 464 41.191 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 Gene3D G3DSA:3.30.230.10 335 466 4.1E-22 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_1369 d872066d87547a39b4ec35d0d90937d1 466 TIGRFAM TIGR00416 sms: DNA repair protein RadA 3 460 1.3E-204 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 Pfam PF01632 Ribosomal protein L35 2 62 1.7E-18 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 Gene3D G3DSA:2.40.50.530 1 65 1.1E-16 T 12-10-2018 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.823 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 SUPERFAMILY SSF143034 2 64 1.96E-19 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 7.7E-18 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 7.7E-18 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 7.7E-18 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1039 f560203e9fdc201e2647ba8da44196ff 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 2.5E-20 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 IM45_1344 c814464f424e7448dd8ab10503048619 552 Gene3D G3DSA:3.50.50.60 10 408 5.4E-149 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1344 c814464f424e7448dd8ab10503048619 552 SUPERFAMILY SSF51905 4 414 1.23E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1344 c814464f424e7448dd8ab10503048619 552 Gene3D G3DSA:3.90.700.10 254 364 5.4E-149 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 IM45_1344 c814464f424e7448dd8ab10503048619 552 PIRSF PIRSF000171 1 254 1.9E-19 T 12-10-2018 IM45_1344 c814464f424e7448dd8ab10503048619 552 PIRSF PIRSF000171 345 542 1.1E-11 T 12-10-2018 IM45_1344 c814464f424e7448dd8ab10503048619 552 SUPERFAMILY SSF56425 244 359 6.58E-39 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 IM45_1344 c814464f424e7448dd8ab10503048619 552 Pfam PF00890 FAD binding domain 10 398 6.4E-97 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 IM45_1344 c814464f424e7448dd8ab10503048619 552 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.2E-5 T 12-10-2018 IM45_1344 c814464f424e7448dd8ab10503048619 552 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 376 383 6.2E-5 T 12-10-2018 IM45_1344 c814464f424e7448dd8ab10503048619 552 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 529 1.8E-202 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 IM45_1344 c814464f424e7448dd8ab10503048619 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.3E-10 T 12-10-2018 IM45_1344 c814464f424e7448dd8ab10503048619 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 361 383 3.3E-10 T 12-10-2018 IM45_1344 c814464f424e7448dd8ab10503048619 552 Gene3D G3DSA:1.20.58.100 437 548 1.0E-38 T 12-10-2018 IM45_1344 c814464f424e7448dd8ab10503048619 552 Pfam PF02910 Fumarate reductase flavoprotein C-term 450 530 1.6E-13 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 IM45_1344 c814464f424e7448dd8ab10503048619 552 SUPERFAMILY SSF46977 440 536 1.06E-28 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 IM45_831 1b36e2c40f1fcb9a698d19b9a9de2ca3 191 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 189 35.478 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like IM45_831 1b36e2c40f1fcb9a698d19b9a9de2ca3 191 Gene3D G3DSA:3.40.50.1950 3 191 6.6E-73 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 IM45_831 1b36e2c40f1fcb9a698d19b9a9de2ca3 191 Pfam PF02441 Flavoprotein 3 166 1.3E-22 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 IM45_831 1b36e2c40f1fcb9a698d19b9a9de2ca3 191 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 4 181 3.5E-66 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like IM45_831 1b36e2c40f1fcb9a698d19b9a9de2ca3 191 SUPERFAMILY SSF52507 3 180 1.15E-55 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 IM45_529 9e146e782d3407d8d0c653655e6f338a 264 SUPERFAMILY SSF51621 4 263 3.01E-101 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 IM45_529 9e146e782d3407d8d0c653655e6f338a 264 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 263 2.7E-114 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 IM45_529 9e146e782d3407d8d0c653655e6f338a 264 PIRSF PIRSF000388 1 264 1.9E-94 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 IM45_529 9e146e782d3407d8d0c653655e6f338a 264 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 258 5.7E-104 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 IM45_529 9e146e782d3407d8d0c653655e6f338a 264 Gene3D G3DSA:3.20.20.60 2 264 1.9E-101 T 12-10-2018 IM45_529 9e146e782d3407d8d0c653655e6f338a 264 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 263 41.339 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 IM45_922 321dfe07f5d029b1a5e27efce9ac6ecf 105 Gene3D G3DSA:2.30.30.390 1 105 7.4E-39 T 12-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 IM45_922 321dfe07f5d029b1a5e27efce9ac6ecf 105 SMART SM00992 3 102 4.0E-40 T 12-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 IM45_922 321dfe07f5d029b1a5e27efce9ac6ecf 105 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 5 94 7.3E-21 T 12-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 IM45_922 321dfe07f5d029b1a5e27efce9ac6ecf 105 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 4 102 1.3E-34 T 12-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 IM45_922 321dfe07f5d029b1a5e27efce9ac6ecf 105 SUPERFAMILY SSF141255 4 94 3.92E-31 T 12-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 IM45_922 321dfe07f5d029b1a5e27efce9ac6ecf 105 Hamap MF_01194 Heat shock protein HspQ [hspQ]. 1 105 38.654 T 12-10-2018 IPR022866 Heat shock protein HspQ IM45_051 81f85b3161874e4446f7e3d02d1dab70 798 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 12 789 0.0 T 12-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 IM45_051 81f85b3161874e4446f7e3d02d1dab70 798 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 13 797 27.488 T 12-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 IM45_051 81f85b3161874e4446f7e3d02d1dab70 798 Pfam PF01553 Acyltransferase 272 413 3.7E-24 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 IM45_051 81f85b3161874e4446f7e3d02d1dab70 798 PIRSF PIRSF000437 19 798 2.1E-260 T 12-10-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 IM45_051 81f85b3161874e4446f7e3d02d1dab70 798 PIRSF PIRSF500064 2 798 8.7E-273 T 12-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 IM45_051 81f85b3161874e4446f7e3d02d1dab70 798 SMART SM00563 289 416 3.3E-27 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 IM45_051 81f85b3161874e4446f7e3d02d1dab70 798 SUPERFAMILY SSF69593 262 471 2.62E-23 T 12-10-2018 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 187 1.9E-48 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 SUPERFAMILY SSF48179 206 299 2.72E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 419 8.1E-15 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 Gene3D G3DSA:3.40.50.720 1 204 6.3E-55 T 12-10-2018 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 PIRSF PIRSF500136 1 420 6.8E-139 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 SUPERFAMILY SSF51735 5 198 3.57E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 Gene3D G3DSA:3.40.50.720 205 420 4.8E-56 T 12-10-2018 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 PIRSF PIRSF000124 4 418 1.1E-67 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 SMART SM00984 324 420 1.5E-18 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 416 2.6E-110 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 SUPERFAMILY SSF52413 310 419 2.75E-21 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 IM45_433 dfe538f9fc6eacab8c5a0aca5f971010 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 293 1.5E-26 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 1.4E-32 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 SUPERFAMILY SSF55174 3 206 6.67E-68 T 12-10-2018 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 SMART SM01390 3 95 7.5E-48 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 Pfam PF01479 S4 domain 97 143 5.0E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 Gene3D G3DSA:3.10.290.10 103 191 2.1E-31 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 34.354 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 2.1E-80 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 SMART SM00363 96 160 1.3E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 Gene3D G3DSA:1.10.1050.10 1 102 5.4E-44 T 12-10-2018 IM45_797 61f13f5e540da6d6cba0059e778fa11e 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_964 1a0a9e758a04c9cd70de2062c87dba12 267 SUPERFAMILY SSF56752 1 252 1.28E-64 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 IM45_964 1a0a9e758a04c9cd70de2062c87dba12 267 Pfam PF01063 Amino-transferase class IV 24 247 1.4E-41 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 IM45_964 1a0a9e758a04c9cd70de2062c87dba12 267 Gene3D G3DSA:3.20.10.10 121 265 3.7E-50 T 12-10-2018 IM45_964 1a0a9e758a04c9cd70de2062c87dba12 267 ProSitePatterns PS00770 Aminotransferases class-IV signature. 173 202 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 IM45_964 1a0a9e758a04c9cd70de2062c87dba12 267 Gene3D G3DSA:3.30.470.10 1 106 8.9E-23 T 12-10-2018 IM45_964 1a0a9e758a04c9cd70de2062c87dba12 267 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 3 263 2.5E-106 T 12-10-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 1 246 4.2E-92 T 12-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 Gene3D G3DSA:3.30.540.10 1 146 4.3E-43 T 12-10-2018 IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 Pfam PF00459 Inositol monophosphatase family 2 234 5.1E-48 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 Gene3D G3DSA:3.40.190.80 147 247 8.9E-30 T 12-10-2018 IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 206 220 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 1 248 38.733 T 12-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 IM45_1257 992dbbe3000827f4364a0fa61776b5a2 249 SUPERFAMILY SSF56655 3 245 2.36E-68 T 12-10-2018 IM45_549 77d133ac0ac4ce727e397f859f6fe960 397 Pfam PF07690 Major Facilitator Superfamily 20 233 6.9E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 IM45_549 77d133ac0ac4ce727e397f859f6fe960 397 Gene3D G3DSA:1.20.1250.20 12 385 1.2E-37 T 12-10-2018 IM45_549 77d133ac0ac4ce727e397f859f6fe960 397 Hamap MF_01529 Multidrug resistance protein MdtH [mdtH]. 1 396 41.419 T 12-10-2018 IPR022855 Multidrug resistance protein MdtH IM45_549 77d133ac0ac4ce727e397f859f6fe960 397 SUPERFAMILY SSF103473 14 386 1.23E-43 T 12-10-2018 IPR036259 MFS transporter superfamily IM45_704 25fe9052e106e24f197fc913bd5215ac 292 Pfam PF01435 Peptidase family M48 75 287 2.2E-37 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 IM45_704 25fe9052e106e24f197fc913bd5215ac 292 Gene3D G3DSA:3.30.2010.10 64 157 1.5E-33 T 12-10-2018 IM45_704 25fe9052e106e24f197fc913bd5215ac 292 Hamap MF_00188 Protease HtpX [htpX]. 1 288 25.096 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 IM45_1125 1b42906cbf4ea7a7342c4c0df57e6a0f 216 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 198 26.022 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 IM45_1125 1b42906cbf4ea7a7342c4c0df57e6a0f 216 SUPERFAMILY SSF52540 1 192 6.68E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1125 1b42906cbf4ea7a7342c4c0df57e6a0f 216 Gene3D G3DSA:3.40.50.300 1 214 1.9E-61 T 12-10-2018 IM45_1125 1b42906cbf4ea7a7342c4c0df57e6a0f 216 Pfam PF01121 Dephospho-CoA kinase 3 182 9.0E-66 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 IM45_1125 1b42906cbf4ea7a7342c4c0df57e6a0f 216 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 189 3.9E-59 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 IM45_286 4011a640fb7972c346aa72f691f4946b 463 Gene3D G3DSA:3.40.50.620 1 305 6.0E-128 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_286 4011a640fb7972c346aa72f691f4946b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 3.4E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 3.4E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 3.4E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 3.4E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 461 2.9E-177 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 SUPERFAMILY SSF52374 1 313 1.61E-95 T 12-10-2018 IM45_286 4011a640fb7972c346aa72f691f4946b 463 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 462 37.13 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 Pfam PF09190 DALR domain 341 403 1.1E-19 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 SMART SM00840 341 403 1.3E-21 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 7.4E-135 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 IM45_286 4011a640fb7972c346aa72f691f4946b 463 Gene3D G3DSA:1.20.120.640 306 462 2.6E-42 T 12-10-2018 IM45_286 4011a640fb7972c346aa72f691f4946b 463 SUPERFAMILY SSF47323 316 461 2.75E-35 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_405 cd356b30dc77ca482d787444a2205954 55 Gene3D G3DSA:2.20.28.120 1 55 4.1E-27 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_405 cd356b30dc77ca482d787444a2205954 55 SUPERFAMILY SSF57829 2 53 5.98E-18 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 IM45_405 cd356b30dc77ca482d787444a2205954 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 4.4E-24 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_405 cd356b30dc77ca482d787444a2205954 55 Pfam PF00471 Ribosomal protein L33 7 53 4.6E-16 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_405 cd356b30dc77ca482d787444a2205954 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.607 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_811 17359445d8d518b5aec49e9c77bbd756 310 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 301 1.1E-88 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 IM45_811 17359445d8d518b5aec49e9c77bbd756 310 SUPERFAMILY SSF53335 16 290 6.27E-48 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_811 17359445d8d518b5aec49e9c77bbd756 310 Gene3D G3DSA:3.40.50.150 98 291 4.8E-42 T 12-10-2018 IM45_811 17359445d8d518b5aec49e9c77bbd756 310 PIRSF PIRSF037167 2 307 2.3E-135 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 IM45_811 17359445d8d518b5aec49e9c77bbd756 310 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 13 294 1.5E-127 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 IM45_811 17359445d8d518b5aec49e9c77bbd756 310 Pfam PF05175 Methyltransferase small domain 129 215 1.2E-14 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 IM45_811 17359445d8d518b5aec49e9c77bbd756 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 204 210 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 IM45_811 17359445d8d518b5aec49e9c77bbd756 310 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 6 300 48.045 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 IM45_1367 6baa931406ea9646d523cbde885dbfe5 245 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 51 181 8.1E-45 T 12-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 IM45_1367 6baa931406ea9646d523cbde885dbfe5 245 Pfam PF01553 Acyltransferase 54 181 2.4E-32 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 IM45_1367 6baa931406ea9646d523cbde885dbfe5 245 SUPERFAMILY SSF69593 6 239 1.7E-62 T 12-10-2018 IM45_1367 6baa931406ea9646d523cbde885dbfe5 245 SMART SM00563 68 183 1.9E-38 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 29 450 5.2E-129 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 Gene3D G3DSA:3.40.1190.10 81 315 3.9E-74 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 SUPERFAMILY SSF53244 318 450 4.27E-36 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 451 31.778 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 393 1.7E-12 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 Pfam PF08245 Mur ligase middle domain 106 296 2.1E-44 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 Pfam PF01225 Mur ligase family, catalytic domain 23 71 1.1E-6 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 SUPERFAMILY SSF63418 1 97 6.15E-23 T 12-10-2018 IPR035911 MurE/MurF, N-terminal IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 SUPERFAMILY SSF53623 100 315 2.35E-50 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 Gene3D G3DSA:3.40.1390.10 1 80 7.2E-21 T 12-10-2018 IM45_1148 502a29d11b35c3dc123dc157e729f8b4 460 Gene3D G3DSA:3.90.190.20 316 456 7.0E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 IM45_155 2836f5e0f63ceff316b86d44d99fb3b2 156 SUPERFAMILY SSF55486 3 150 2.44E-46 T 12-10-2018 IM45_155 2836f5e0f63ceff316b86d44d99fb3b2 156 Gene3D G3DSA:3.40.390.30 1 155 5.8E-54 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 IM45_155 2836f5e0f63ceff316b86d44d99fb3b2 156 Pfam PF02130 Uncharacterized protein family UPF0054 24 144 1.6E-35 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 IM45_155 2836f5e0f63ceff316b86d44d99fb3b2 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 114 124 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site IM45_155 2836f5e0f63ceff316b86d44d99fb3b2 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 148 23.296 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 IM45_155 2836f5e0f63ceff316b86d44d99fb3b2 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 145 3.9E-34 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 IM45_163 2acd9cb8814a2d778e5dbe07cbb8fbe2 263 Gene3D G3DSA:3.30.1400.10 121 261 1.8E-50 T 12-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 IM45_163 2acd9cb8814a2d778e5dbe07cbb8fbe2 263 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 126 260 5.0E-55 T 12-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 IM45_163 2acd9cb8814a2d778e5dbe07cbb8fbe2 263 SMART SM00771 123 253 5.4E-65 T 12-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 IM45_163 2acd9cb8814a2d778e5dbe07cbb8fbe2 263 SUPERFAMILY SSF64383 123 254 4.45E-46 T 12-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 IM45_163 2acd9cb8814a2d778e5dbe07cbb8fbe2 263 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 126 251 2.8E-46 T 12-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 IM45_163 2acd9cb8814a2d778e5dbe07cbb8fbe2 263 Hamap MF_00509 Cell division protein ZipA [zipA]. 3 255 22.697 T 12-10-2018 IPR011919 Cell division protein ZipA GO:0016021|GO:0090529 IM45_163 2acd9cb8814a2d778e5dbe07cbb8fbe2 263 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 105 253 2.5E-58 T 12-10-2018 IPR011919 Cell division protein ZipA GO:0016021|GO:0090529 IM45_561 f6674a4f18614990e34ca5174578e375 388 Pfam PF00155 Aminotransferase class I and II 43 382 7.9E-53 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 IM45_561 f6674a4f18614990e34ca5174578e375 388 Gene3D G3DSA:3.40.640.10 59 286 3.7E-126 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_561 f6674a4f18614990e34ca5174578e375 388 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 22 382 4.2E-131 T 12-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 IM45_561 f6674a4f18614990e34ca5174578e375 388 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 235 244 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 IM45_561 f6674a4f18614990e34ca5174578e375 388 Gene3D G3DSA:3.90.1150.10 43 380 3.7E-126 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_561 f6674a4f18614990e34ca5174578e375 388 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 5 386 44.488 T 12-10-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 IM45_561 f6674a4f18614990e34ca5174578e375 388 SUPERFAMILY SSF53383 5 385 1.71E-99 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_479 e0c9a4d3c80b4946e72069e35d1afeb5 256 SUPERFAMILY SSF53850 1 253 5.03E-61 T 12-10-2018 IM45_479 e0c9a4d3c80b4946e72069e35d1afeb5 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 252 7.4E-59 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF IM45_479 e0c9a4d3c80b4946e72069e35d1afeb5 256 Gene3D G3DSA:3.40.190.10 35 243 1.8E-67 T 12-10-2018 IM45_479 e0c9a4d3c80b4946e72069e35d1afeb5 256 SMART SM00062 34 253 2.6E-61 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF IM45_479 e0c9a4d3c80b4946e72069e35d1afeb5 256 Gene3D G3DSA:3.40.190.10 117 214 1.8E-67 T 12-10-2018 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 SUPERFAMILY SSF52540 1 214 1.15E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 4.7E-71 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 Gene3D G3DSA:3.40.50.300 1 218 6.4E-73 T 12-10-2018 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 Hamap MF_00235 Adenylate kinase [adk]. 1 214 44.507 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 Pfam PF00406 Adenylate kinase 5 185 2.5E-54 T 12-10-2018 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 Pfam PF05191 Adenylate kinase, active site lid 123 158 8.2E-14 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 PRINTS PR00094 Adenylate kinase signature 173 187 8.9E-32 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 PRINTS PR00094 Adenylate kinase signature 156 171 8.9E-32 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 PRINTS PR00094 Adenylate kinase signature 4 17 8.9E-32 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 PRINTS PR00094 Adenylate kinase signature 32 46 8.9E-32 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 PRINTS PR00094 Adenylate kinase signature 81 97 8.9E-32 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 IM45_278 9e4fbc94fcbed39c9e046c1708745e0a 220 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 IM45_1099 001149112049e3c50347799a864631ae 221 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 213 4.7E-89 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 IM45_1099 001149112049e3c50347799a864631ae 221 Gene3D G3DSA:3.30.190.20 25 212 1.0E-67 T 12-10-2018 IM45_1099 001149112049e3c50347799a864631ae 221 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_1099 001149112049e3c50347799a864631ae 221 Gene3D G3DSA:3.40.50.790 68 159 1.0E-67 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich IM45_1099 001149112049e3c50347799a864631ae 221 PIRSF PIRSF002155 1 215 2.3E-64 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_1099 001149112049e3c50347799a864631ae 221 Pfam PF00687 Ribosomal protein L1p/L10e family 31 211 9.9E-42 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein IM45_1099 001149112049e3c50347799a864631ae 221 SUPERFAMILY SSF56808 6 212 3.92E-66 T 12-10-2018 IPR023674 Ribosomal protein L1-like IM45_1099 001149112049e3c50347799a864631ae 221 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 220 35.243 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 284 335 4.5E-4 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 255 283 7.3E-4 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 379 413 4.0E-9 T 12-10-2018 IPR001451 Hexapeptide repeat IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 387 415 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 Gene3D G3DSA:3.90.550.10 1 211 3.7E-53 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 SUPERFAMILY SSF51161 239 421 5.47E-51 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 SUPERFAMILY SSF53448 1 236 4.73E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 Pfam PF12804 MobA-like NTP transferase domain 6 117 2.9E-12 T 12-10-2018 IPR025877 MobA-like NTP transferase IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 436 37.289 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 Gene3D G3DSA:2.160.10.10 213 439 8.9E-68 T 12-10-2018 IM45_325 1b0df3764ece6d8984207ec1058c58a0 440 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 439 1.4E-175 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 IM45_763 f58735748bc2e69aace970079082dd2b 63 SUPERFAMILY SSF46561 3 60 9.29E-19 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_763 f58735748bc2e69aace970079082dd2b 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 1.4E-19 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_763 f58735748bc2e69aace970079082dd2b 63 Pfam PF00831 Ribosomal L29 protein 4 59 8.6E-21 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_763 f58735748bc2e69aace970079082dd2b 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 16.821 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_763 f58735748bc2e69aace970079082dd2b 63 Gene3D G3DSA:1.10.287.310 1 62 6.6E-25 T 12-10-2018 IM45_787 6d653be47a07fb865b359e4e4b4692a9 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 142 8.4E-31 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P IM45_787 6d653be47a07fb865b359e4e4b4692a9 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 18.899 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 IM45_787 6d653be47a07fb865b359e4e4b4692a9 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 4.9E-51 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_787 6d653be47a07fb865b359e4e4b4692a9 144 Gene3D G3DSA:3.100.10.10 70 144 4.4E-13 T 12-10-2018 IM45_787 6d653be47a07fb865b359e4e4b4692a9 144 SUPERFAMILY SSF52080 4 142 7.98E-46 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 Gene3D G3DSA:3.40.50.300 176 455 2.1E-103 T 12-10-2018 IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 SUPERFAMILY SSF48024 17 128 7.45E-37 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 SUPERFAMILY SSF52540 196 448 1.86E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 SMART SM00382 215 421 0.0013 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 Pfam PF00772 DnaB-like helicase N terminal domain 19 120 7.4E-35 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 Pfam PF03796 DnaB-like helicase C terminal domain 198 454 4.8E-111 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 18 456 2.2E-174 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 IM45_1215 e685feb684e5b9c038ad7ce91e0ba240 462 Gene3D G3DSA:1.10.860.10 11 175 1.1E-52 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal IM45_916 f0c54aa73a9d6b6a9a014e615c159429 362 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 318 338 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 IM45_916 f0c54aa73a9d6b6a9a014e615c159429 362 Gene3D G3DSA:3.20.20.70 28 362 1.8E-136 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_916 f0c54aa73a9d6b6a9a014e615c159429 362 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 28 362 48.858 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 IM45_916 f0c54aa73a9d6b6a9a014e615c159429 362 Pfam PF01180 Dihydroorotate dehydrogenase 72 362 1.8E-84 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 IM45_916 f0c54aa73a9d6b6a9a014e615c159429 362 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 106 125 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 IM45_916 f0c54aa73a9d6b6a9a014e615c159429 362 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 29 362 3.2E-146 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 IM45_916 f0c54aa73a9d6b6a9a014e615c159429 362 SUPERFAMILY SSF51395 27 361 2.82E-100 T 12-10-2018 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 SUPERFAMILY SSF53927 223 531 4.31E-124 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 Gene3D G3DSA:3.40.140.20 220 375 1.2E-53 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 PIRSF PIRSF000414 6 531 7.1E-218 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 10 531 3.7E-235 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 SUPERFAMILY SSF52335 9 199 3.4E-66 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 9 531 43.163 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 SMART SM00798 139 463 4.0E-188 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 Pfam PF02142 MGS-like domain 22 134 1.3E-24 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 Pfam PF01808 AICARFT/IMPCHase bienzyme 139 462 6.4E-112 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 Gene3D G3DSA:3.40.50.1380 7 200 2.3E-81 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 SMART SM00851 21 134 1.1E-50 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain IM45_095 938f7100e71645cd691d3b2ef2c5d30b 531 Gene3D G3DSA:3.40.140.20 394 531 5.4E-58 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_1067 6759678968b95df3f669b554f6e1680e 317 Gene3D G3DSA:3.30.1490.20 138 202 5.7E-112 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 IM45_1067 6759678968b95df3f669b554f6e1680e 317 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 297 4.1E-72 T 12-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 IM45_1067 6759678968b95df3f669b554f6e1680e 317 Gene3D G3DSA:3.40.50.20 8 115 5.7E-112 T 12-10-2018 IM45_1067 6759678968b95df3f669b554f6e1680e 317 Hamap MF_00162 Glutathione synthetase [gshB]. 1 317 148.905 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 IM45_1067 6759678968b95df3f669b554f6e1680e 317 SUPERFAMILY SSF52440 3 123 2.68E-43 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily IM45_1067 6759678968b95df3f669b554f6e1680e 317 TIGRFAM TIGR01380 glut_syn: glutathione synthase 3 313 2.8E-127 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 IM45_1067 6759678968b95df3f669b554f6e1680e 317 SUPERFAMILY SSF56059 124 313 4.64E-53 T 12-10-2018 IM45_1067 6759678968b95df3f669b554f6e1680e 317 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 121 2.2E-42 T 12-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 IM45_1067 6759678968b95df3f669b554f6e1680e 317 Gene3D G3DSA:3.30.470.20 116 296 5.7E-112 T 12-10-2018 IM45_370 d5b8ef1f1aafe2cea48ab36b85f343b5 105 Gene3D G3DSA:1.10.140.10 2 105 2.5E-58 T 12-10-2018 IPR023453 Methionine repressor MetJ domain superfamily IM45_370 d5b8ef1f1aafe2cea48ab36b85f343b5 105 Pfam PF01340 Met Apo-repressor, MetJ 3 99 1.7E-55 T 12-10-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 IM45_370 d5b8ef1f1aafe2cea48ab36b85f343b5 105 SUPERFAMILY SSF47598 2 104 2.22E-54 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 IM45_370 d5b8ef1f1aafe2cea48ab36b85f343b5 105 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 10 101 2.0E-43 T 12-10-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 IM45_370 d5b8ef1f1aafe2cea48ab36b85f343b5 105 Hamap MF_00744 Met repressor [metJ]. 1 105 37.859 T 12-10-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 SUPERFAMILY SSF52954 463 569 1.12E-29 T 12-10-2018 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 459 9.1E-46 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 571 40.612 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 Pfam PF03129 Anticodon binding domain 476 568 7.0E-18 T 12-10-2018 IPR004154 Anticodon-binding IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 567 5.8E-245 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 SUPERFAMILY SSF55681 10 478 2.87E-102 T 12-10-2018 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 Gene3D G3DSA:3.30.930.10 11 465 2.0E-226 T 12-10-2018 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 Gene3D G3DSA:3.40.50.800 4 554 2.0E-226 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 2.1E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.1E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.1E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 2.1E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 Pfam PF04073 Aminoacyl-tRNA editing domain 258 377 1.6E-19 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 SUPERFAMILY SSF55826 218 389 1.05E-20 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 IM45_1335 23a03ed4b35ce4d6d89c0caa9bc818e3 575 Gene3D G3DSA:3.90.960.10 240 389 2.0E-226 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 SUPERFAMILY SSF54506 1 274 7.86E-52 T 12-10-2018 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 Gene3D G3DSA:3.10.310.10 115 261 5.4E-102 T 12-10-2018 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 274 38.162 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 Gene3D G3DSA:3.10.310.10 3 270 5.4E-102 T 12-10-2018 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 Pfam PF01678 Diaminopimelate epimerase 152 265 2.0E-28 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 Pfam PF01678 Diaminopimelate epimerase 3 123 1.2E-30 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 IM45_295 0da933c8432ed897f709bb6a26fd9cd7 274 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 272 1.7E-95 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 IM45_411 99139865d3b78510aca2e570d1b7a391 213 SUPERFAMILY SSF53271 3 209 4.69E-43 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like IM45_411 99139865d3b78510aca2e570d1b7a391 213 Pfam PF00156 Phosphoribosyl transferase domain 55 154 5.2E-7 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 IM45_411 99139865d3b78510aca2e570d1b7a391 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 187 1.7E-57 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_411 99139865d3b78510aca2e570d1b7a391 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 29.153 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 IM45_411 99139865d3b78510aca2e570d1b7a391 213 Gene3D G3DSA:3.40.50.2020 1 213 1.2E-65 T 12-10-2018 IM45_1320 cf37de5ed3da4b150845b9794ae93e25 157 Gene3D G3DSA:3.40.50.960 1 156 1.7E-59 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1320 cf37de5ed3da4b150845b9794ae93e25 157 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 1.2E-51 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1320 cf37de5ed3da4b150845b9794ae93e25 157 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 30.073 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1320 cf37de5ed3da4b150845b9794ae93e25 157 SUPERFAMILY SSF52121 4 154 1.7E-55 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1320 cf37de5ed3da4b150845b9794ae93e25 157 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 7.7E-52 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1241 18adc0e00ded73005b60721114995b90 277 SUPERFAMILY SSF53335 17 265 2.07E-74 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_1241 18adc0e00ded73005b60721114995b90 277 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 11 263 1.8E-83 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 IM45_1241 18adc0e00ded73005b60721114995b90 277 Gene3D G3DSA:1.10.8.100 201 268 1.3E-23 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 IM45_1241 18adc0e00ded73005b60721114995b90 277 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 IM45_1241 18adc0e00ded73005b60721114995b90 277 Pfam PF00398 Ribosomal RNA adenine dimethylase 12 265 5.4E-71 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm IM45_1241 18adc0e00ded73005b60721114995b90 277 Gene3D G3DSA:3.40.50.150 1 199 2.6E-63 T 12-10-2018 IM45_1241 18adc0e00ded73005b60721114995b90 277 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 265 53.298 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 IM45_1241 18adc0e00ded73005b60721114995b90 277 SMART SM00650 25 198 5.8E-70 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 IM45_564 159fde035e7396825858675eef8f10ec 226 Pfam PF13500 AAA domain 3 212 1.8E-32 T 12-10-2018 IM45_564 159fde035e7396825858675eef8f10ec 226 SUPERFAMILY SSF52540 3 218 4.62E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_564 159fde035e7396825858675eef8f10ec 226 PIRSF PIRSF006755 1 225 5.6E-73 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 IM45_564 159fde035e7396825858675eef8f10ec 226 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 218 28.833 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 IM45_564 159fde035e7396825858675eef8f10ec 226 Gene3D G3DSA:3.40.50.300 2 224 4.3E-61 T 12-10-2018 IM45_564 159fde035e7396825858675eef8f10ec 226 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 176 7.1E-56 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Gene3D G3DSA:3.30.1370.10 551 621 2.1E-16 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 PIRSF PIRSF005499 2 704 3.6E-291 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Gene3D G3DSA:2.40.50.140 622 693 3.5E-26 T 12-10-2018 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Pfam PF00013 KH domain 556 613 6.4E-6 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SUPERFAMILY SSF50249 611 692 5.0E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 320 3.0E-20 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Gene3D G3DSA:3.30.230.70 232 550 4.5E-114 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SUPERFAMILY SSF46915 239 320 4.18E-16 T 12-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SUPERFAMILY SSF54211 297 468 4.4E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 1.7E-18 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Pfam PF01138 3' exoribonuclease family, domain 1 324 456 7.9E-25 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SUPERFAMILY SSF55666 450 546 7.85E-26 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Pfam PF03725 3' exoribonuclease family, domain 2 148 210 1.4E-13 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Pfam PF03725 3' exoribonuclease family, domain 2 460 528 2.2E-4 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SUPERFAMILY SSF54211 4 144 2.13E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SUPERFAMILY SSF54791 554 639 1.33E-20 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SMART SM00316 620 690 2.3E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Pfam PF00575 S1 RNA binding domain 619 690 3.0E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Gene3D G3DSA:3.30.230.70 2 229 5.5E-77 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 693 29.337 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SUPERFAMILY SSF55666 145 235 2.88E-27 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 SMART SM00322 552 617 9.5E-8 T 12-10-2018 IPR004087 K Homology domain GO:0003676 IM45_1375 daf19255445ce2ede26fd0438c28157d 706 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 691 0.0 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 IM45_918 6c1d04896e3621541cf95ee942c62f0c 172 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 172 49.325 T 12-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_918 6c1d04896e3621541cf95ee942c62f0c 172 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 171 1.2E-88 T 12-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_918 6c1d04896e3621541cf95ee942c62f0c 172 Gene3D G3DSA:3.10.129.10 2 172 5.0E-62 T 12-10-2018 IM45_918 6c1d04896e3621541cf95ee942c62f0c 172 Pfam PF07977 FabA-like domain 29 158 2.2E-51 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_918 6c1d04896e3621541cf95ee942c62f0c 172 SUPERFAMILY SSF54637 4 168 7.46E-53 T 12-10-2018 IPR029069 HotDog domain superfamily IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 Pfam PF02911 Formyl transferase, C-terminal domain 207 304 3.9E-26 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 307 33.916 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 Gene3D G3DSA:3.10.25.10 210 313 1.0E-32 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 SUPERFAMILY SSF53328 5 207 1.7E-62 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 Pfam PF00551 Formyl transferase 7 183 2.5E-43 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 6 310 2.5E-98 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 Gene3D G3DSA:3.40.50.170 1 209 1.3E-75 T 12-10-2018 IM45_927 7e489cf0a6e50eb6bee30cf9a8ad08ed 315 SUPERFAMILY SSF50486 208 310 3.61E-32 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 IM45_221 151080810d718bba800911c769ab95d5 500 Pfam PF00875 DNA photolyase 28 198 1.0E-36 T 12-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 IM45_221 151080810d718bba800911c769ab95d5 500 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 349 361 - T 12-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal IM45_221 151080810d718bba800911c769ab95d5 500 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 369 388 - T 12-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal IM45_221 151080810d718bba800911c769ab95d5 500 Pfam PF03441 FAD binding domain of DNA photolyase 299 493 6.7E-79 T 12-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 IM45_221 151080810d718bba800911c769ab95d5 500 PRINTS PR00147 DNA photolyase signature 168 184 8.2E-26 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 IM45_221 151080810d718bba800911c769ab95d5 500 PRINTS PR00147 DNA photolyase signature 349 365 8.2E-26 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 IM45_221 151080810d718bba800911c769ab95d5 500 PRINTS PR00147 DNA photolyase signature 408 422 8.2E-26 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 IM45_221 151080810d718bba800911c769ab95d5 500 PRINTS PR00147 DNA photolyase signature 369 387 8.2E-26 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 IM45_221 151080810d718bba800911c769ab95d5 500 Gene3D G3DSA:3.40.50.620 29 228 1.5E-65 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_221 151080810d718bba800911c769ab95d5 500 SUPERFAMILY SSF52425 27 211 3.14E-46 T 12-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 IM45_221 151080810d718bba800911c769ab95d5 500 SUPERFAMILY SSF48173 227 497 8.76E-100 T 12-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 IM45_221 151080810d718bba800911c769ab95d5 500 Gene3D G3DSA:1.25.40.80 157 313 1.5E-65 T 12-10-2018 IM45_221 151080810d718bba800911c769ab95d5 500 Gene3D G3DSA:1.10.579.10 317 499 5.0E-79 T 12-10-2018 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 1.3E-36 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 Pfam PF01084 Ribosomal protein S18 19 68 9.0E-25 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 20.994 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 SUPERFAMILY SSF46911 3 71 2.62E-28 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.3E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.3E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.3E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.3E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 Gene3D G3DSA:4.10.640.10 20 75 3.9E-28 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1261 17578e35b92ef75d0fc8c6ef2036e9ed 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 71 9.0E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1419 268318631eadc77f3a5dbacfc3e7334d 106 SUPERFAMILY SSF102829 6 94 5.1E-23 T 12-10-2018 IPR036192 Cell division protein ZapA-like superfamily IM45_1419 268318631eadc77f3a5dbacfc3e7334d 106 Gene3D G3DSA:1.10.20.30 1 47 4.7E-21 T 12-10-2018 IM45_1419 268318631eadc77f3a5dbacfc3e7334d 106 Pfam PF05164 Cell division protein ZapA 6 89 6.2E-17 T 12-10-2018 IPR007838 Cell division protein ZapA-like IM45_718 5adb7538d01f640de226035527f92e77 195 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 193 1.8E-55 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 IM45_718 5adb7538d01f640de226035527f92e77 195 Pfam PF01330 RuvA N terminal domain 2 62 9.4E-16 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 IM45_718 5adb7538d01f640de226035527f92e77 195 SUPERFAMILY SSF50249 2 63 1.94E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_718 5adb7538d01f640de226035527f92e77 195 Gene3D G3DSA:2.40.50.140 1 66 1.0E-21 T 12-10-2018 IM45_718 5adb7538d01f640de226035527f92e77 195 SUPERFAMILY SSF47781 66 137 2.22E-21 T 12-10-2018 IPR010994 RuvA domain 2-like IM45_718 5adb7538d01f640de226035527f92e77 195 Pfam PF14520 Helix-hairpin-helix domain 72 130 2.5E-15 T 12-10-2018 IM45_718 5adb7538d01f640de226035527f92e77 195 Gene3D G3DSA:1.10.8.10 148 195 6.8E-22 T 12-10-2018 IM45_718 5adb7538d01f640de226035527f92e77 195 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 29.485 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 IM45_718 5adb7538d01f640de226035527f92e77 195 SMART SM00278 108 127 0.044 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 IM45_718 5adb7538d01f640de226035527f92e77 195 SMART SM00278 73 92 0.045 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 IM45_718 5adb7538d01f640de226035527f92e77 195 SUPERFAMILY SSF46929 150 193 8.76E-9 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily IM45_718 5adb7538d01f640de226035527f92e77 195 Gene3D G3DSA:1.10.150.20 67 139 3.3E-24 T 12-10-2018 IM45_718 5adb7538d01f640de226035527f92e77 195 Pfam PF07499 RuvA, C-terminal domain 152 192 1.2E-11 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 IM45_268 8ebbd9fa3ebcd697492b29addee2bbff 200 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 3 186 9.5E-67 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 IM45_268 8ebbd9fa3ebcd697492b29addee2bbff 200 Pfam PF01926 50S ribosome-binding GTPase 21 139 5.8E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_268 8ebbd9fa3ebcd697492b29addee2bbff 200 SUPERFAMILY SSF52540 20 191 4.86E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_268 8ebbd9fa3ebcd697492b29addee2bbff 200 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 7 190 25.912 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 IM45_268 8ebbd9fa3ebcd697492b29addee2bbff 200 Gene3D G3DSA:3.40.50.300 1 197 1.0E-50 T 12-10-2018 IM45_1131 5d135478e57b7ab32495532827632fa8 306 Gene3D G3DSA:3.30.1700.10 129 306 5.5E-61 T 12-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 IM45_1131 5d135478e57b7ab32495532827632fa8 306 SUPERFAMILY SSF54211 134 278 1.74E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_1131 5d135478e57b7ab32495532827632fa8 306 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 277 1.2E-93 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 IM45_1131 5d135478e57b7ab32495532827632fa8 306 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 302 6.8E-129 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 IM45_1131 5d135478e57b7ab32495532827632fa8 306 SUPERFAMILY SSF54211 3 124 1.74E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_1131 5d135478e57b7ab32495532827632fa8 306 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 281 39.729 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 IM45_1131 5d135478e57b7ab32495532827632fa8 306 Gene3D G3DSA:3.30.230.20 1 128 1.7E-45 T 12-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 IM45_1201 403e1b75fd11701df93e199f1a2a805a 285 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 284 19.755 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 IM45_1201 403e1b75fd11701df93e199f1a2a805a 285 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 142 154 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 IM45_1201 403e1b75fd11701df93e199f1a2a805a 285 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 281 2.4E-91 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 IM45_1201 403e1b75fd11701df93e199f1a2a805a 285 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 279 6.6E-75 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 Gene3D G3DSA:3.90.650.10 171 346 5.2E-66 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 Pfam PF00586 AIR synthase related protein, N-terminal domain 73 164 3.8E-15 T 12-10-2018 IPR016188 PurM-like, N-terminal domain IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 335 1.0E-140 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 Gene3D G3DSA:3.30.1330.10 6 170 8.2E-65 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 344 44.506 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 337 1.7E-34 T 12-10-2018 IPR010918 PurM-like, C-terminal domain IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 SUPERFAMILY SSF55326 7 170 1.45E-48 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_179 70b58cf82b31f7d22a467f8396cb678e 347 SUPERFAMILY SSF56042 171 337 2.09E-59 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_674 7ec70565f82017fe62a47d170d060823 179 SUPERFAMILY SSF53178 2 173 1.83E-53 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 IM45_674 7ec70565f82017fe62a47d170d060823 179 Gene3D G3DSA:3.40.50.1470 1 177 5.3E-55 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 IM45_674 7ec70565f82017fe62a47d170d060823 179 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 94 104 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 IM45_674 7ec70565f82017fe62a47d170d060823 179 Pfam PF01195 Peptidyl-tRNA hydrolase 2 172 3.5E-43 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 IM45_674 7ec70565f82017fe62a47d170d060823 179 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 173 1.3E-52 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 IM45_1141 365fe1a45f41d40bed5af27109672536 357 SUPERFAMILY SSF53756 4 355 1.66E-116 T 12-10-2018 IM45_1141 365fe1a45f41d40bed5af27109672536 357 Gene3D G3DSA:3.40.50.2000 7 159 3.2E-111 T 12-10-2018 IM45_1141 365fe1a45f41d40bed5af27109672536 357 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 183 328 4.2E-31 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 IM45_1141 365fe1a45f41d40bed5af27109672536 357 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 349 1.3E-107 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1141 365fe1a45f41d40bed5af27109672536 357 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 143 2.0E-41 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1141 365fe1a45f41d40bed5af27109672536 357 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 355 33.783 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1141 365fe1a45f41d40bed5af27109672536 357 Gene3D G3DSA:3.40.50.2000 160 321 3.2E-111 T 12-10-2018 IM45_1250 0c73f559d624666706f90c7b34d4ef67 96 Gene3D G3DSA:3.10.20.280 1 89 7.6E-32 T 12-10-2018 IPR037021 RnfH superfamily IM45_1250 0c73f559d624666706f90c7b34d4ef67 96 SUPERFAMILY SSF54285 4 79 1.11E-22 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp IM45_1250 0c73f559d624666706f90c7b34d4ef67 96 Hamap MF_00460 Protein RnfH [rnfH]. 4 95 24.079 T 12-10-2018 IPR005346 RnfH protein IM45_1250 0c73f559d624666706f90c7b34d4ef67 96 Pfam PF03658 RnfH family Ubiquitin 4 87 7.5E-32 T 12-10-2018 IPR005346 RnfH protein IM45_951 1ca7d4ee9922057210cf0f1b17a0ec24 395 Pfam PF02687 FtsX-like permease family 296 386 1.1E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 IM45_951 1ca7d4ee9922057210cf0f1b17a0ec24 395 Pfam PF12704 MacB-like periplasmic core domain 27 211 3.9E-10 T 12-10-2018 IPR025857 MacB-like periplasmic core domain IM45_951 1ca7d4ee9922057210cf0f1b17a0ec24 395 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 395 1.3E-116 T 12-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 IM45_966 e99aae54da54472f5ddb06fee2ba9a5a 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 75 8.4E-35 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 IM45_966 e99aae54da54472f5ddb06fee2ba9a5a 78 Gene3D G3DSA:1.10.1200.10 1 78 2.7E-27 T 12-10-2018 IPR036736 ACP-like superfamily IM45_966 e99aae54da54472f5ddb06fee2ba9a5a 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 21.686 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 IM45_966 e99aae54da54472f5ddb06fee2ba9a5a 78 SUPERFAMILY SSF47336 2 76 4.32E-22 T 12-10-2018 IPR036736 ACP-like superfamily IM45_966 e99aae54da54472f5ddb06fee2ba9a5a 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.2E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain IM45_966 e99aae54da54472f5ddb06fee2ba9a5a 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Gene3D G3DSA:3.30.54.20 130 187 8.6E-58 T 12-10-2018 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Gene3D G3DSA:3.30.980.10 69 222 8.6E-58 T 12-10-2018 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 634 32.316 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Pfam PF02824 TGS domain 4 61 1.9E-6 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 SUPERFAMILY SSF55681 243 525 1.17E-91 T 12-10-2018 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 SMART SM00863 170 219 7.2E-15 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 6.9E-54 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 6.9E-54 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 6.9E-54 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 6.9E-54 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 6.9E-54 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 SUPERFAMILY SSF81271 3 61 5.89E-12 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Gene3D G3DSA:3.40.50.800 532 641 2.2E-29 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 219 7.5E-10 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 631 3.6E-227 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 SUPERFAMILY SSF52954 529 636 2.57E-29 T 12-10-2018 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Pfam PF03129 Anticodon binding domain 541 629 2.2E-19 T 12-10-2018 IPR004154 Anticodon-binding IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Gene3D G3DSA:3.30.930.10 223 531 3.8E-121 T 12-10-2018 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Gene3D G3DSA:3.10.20.30 1 64 5.7E-13 T 12-10-2018 IPR012675 Beta-grasp domain superfamily IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 SUPERFAMILY SSF55186 64 239 6.28E-56 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 IM45_1043 dafdfe825c8879c3a97f7640cde7a322 642 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 318 529 4.8E-49 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 Gene3D G3DSA:3.30.70.3400 212 424 5.0E-49 T 12-10-2018 IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 334 583 1.6E-76 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 Gene3D G3DSA:1.20.1640.10 425 597 1.5E-7 T 12-10-2018 IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 112 590 9.9E-141 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 Pfam PF13721 SecD export protein N-terminal TM region 1 92 6.6E-26 T 12-10-2018 IPR027398 SecD export protein N-terminal TM domain IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 SUPERFAMILY SSF82866 399 595 4.71E-39 T 12-10-2018 IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 Gene3D G3DSA:3.30.1360.200 267 420 5.0E-49 T 12-10-2018 IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 604 43.685 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 Pfam PF07549 SecD/SecF GG Motif 105 129 1.8E-6 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site IM45_1312 ff002bf40dc3acd5529171ca263e6fee 604 Pfam PF02355 Protein export membrane protein 423 591 5.6E-16 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial IM45_1263 f4c88657b3d23cc30f0cc1421ed6a857 106 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 3 101 8.3E-31 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 IM45_1263 f4c88657b3d23cc30f0cc1421ed6a857 106 PIRSF PIRSF003135 1 103 1.6E-43 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 IM45_1263 f4c88657b3d23cc30f0cc1421ed6a857 106 Gene3D G3DSA:2.40.50.140 1 106 1.0E-33 T 12-10-2018 IM45_1263 f4c88657b3d23cc30f0cc1421ed6a857 106 SUPERFAMILY SSF50249 1 105 1.23E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1263 f4c88657b3d23cc30f0cc1421ed6a857 106 Hamap MF_00720 Primosomal replication protein N [priB]. 2 102 21.571 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 IM45_1263 f4c88657b3d23cc30f0cc1421ed6a857 106 Pfam PF00436 Single-strand binding protein family 3 88 4.4E-8 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 Pfam PF05239 PRC-barrel domain 100 173 7.8E-8 T 12-10-2018 IPR027275 PRC-barrel domain IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 Gene3D G3DSA:2.30.30.240 97 178 3.0E-28 T 12-10-2018 IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 10 177 5.5E-55 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 SUPERFAMILY SSF50346 102 177 9.81E-18 T 12-10-2018 IPR011033 PRC-barrel-like superfamily IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 Pfam PF01782 RimM N-terminal domain 12 93 2.1E-20 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 9 178 22.67 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 Gene3D G3DSA:2.40.30.60 2 96 3.2E-30 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 IM45_463 28e45dc5dcc46db58b543e81c0b6aee2 178 SUPERFAMILY SSF50447 10 96 2.86E-20 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 4.9E-14 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 SUPERFAMILY SSF55261 288 418 1.18E-39 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 Pfam PF02938 GAD domain 308 406 4.9E-23 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 584 32.453 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 SUPERFAMILY SSF55681 108 583 5.36E-102 T 12-10-2018 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 Gene3D G3DSA:3.30.1360.30 271 420 9.8E-195 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 Gene3D G3DSA:3.30.930.10 118 576 9.8E-195 T 12-10-2018 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 558 2.2E-109 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 Gene3D G3DSA:2.40.50.140 1 105 3.5E-29 T 12-10-2018 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 584 9.5E-249 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 IM45_724 90f2f6ae47c4bb76f840cd40c3eabb90 589 SUPERFAMILY SSF50249 1 105 3.43E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 SUPERFAMILY SSF54752 272 327 3.92E-19 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 Gene3D G3DSA:3.30.250.10 271 329 1.2E-23 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 Hamap MF_00268 Protein RecA [recA]. 7 331 50.417 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 SMART SM00382 59 230 1.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 SUPERFAMILY SSF52540 6 269 2.47E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 Gene3D G3DSA:3.40.50.300 28 269 2.8E-80 T 12-10-2018 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 4.8E-170 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 Pfam PF00154 recA bacterial DNA recombination protein 9 270 2.6E-141 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 PRINTS PR00142 RecA protein signature 129 158 3.8E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 PRINTS PR00142 RecA protein signature 245 274 3.8E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 PRINTS PR00142 RecA protein signature 212 240 3.8E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 PRINTS PR00142 RecA protein signature 167 196 3.8E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 PRINTS PR00142 RecA protein signature 95 124 3.8E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 PRINTS PR00142 RecA protein signature 299 316 3.8E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 IM45_477 9ccacf10c3df7626b2a4ca0a876a8c54 347 ProSitePatterns PS00321 recA signature. 215 223 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 IM45_863 273255fe9449c1731da30e3d53573d84 86 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 IM45_863 273255fe9449c1731da30e3d53573d84 86 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 78 1.3E-9 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 IM45_863 273255fe9449c1731da30e3d53573d84 86 Gene3D G3DSA:3.10.20.30 2 86 2.2E-15 T 12-10-2018 IPR012675 Beta-grasp domain superfamily IM45_863 273255fe9449c1731da30e3d53573d84 86 SUPERFAMILY SSF54292 3 86 6.2E-16 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 6.1E-66 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 6.1E-66 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 6.1E-66 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 6.1E-66 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 6.1E-66 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 Pfam PF06723 MreB/Mbl protein 11 338 6.8E-150 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 SUPERFAMILY SSF53067 154 340 3.82E-50 T 12-10-2018 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 Gene3D G3DSA:3.30.420.40 14 331 4.3E-130 T 12-10-2018 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 4.2E-169 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 Gene3D G3DSA:3.90.640.10 190 263 4.3E-130 T 12-10-2018 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 SUPERFAMILY SSF53067 9 152 2.38E-37 T 12-10-2018 IM45_117 161aa6e67559993176b73ed224c5c6e4 347 Gene3D G3DSA:3.30.420.40 158 321 4.3E-130 T 12-10-2018 IM45_1306 b25675506a19a38cbbd0b3cb655412ca 353 Gene3D G3DSA:3.40.1780.10 14 344 3.4E-109 T 12-10-2018 IM45_1306 b25675506a19a38cbbd0b3cb655412ca 353 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 345 45.584 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 IM45_1306 b25675506a19a38cbbd0b3cb655412ca 353 Pfam PF02547 Queuosine biosynthesis protein 4 344 1.9E-124 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 IM45_1306 b25675506a19a38cbbd0b3cb655412ca 353 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 345 2.3E-144 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 IM45_1306 b25675506a19a38cbbd0b3cb655412ca 353 Gene3D G3DSA:2.40.10.240 64 163 3.4E-109 T 12-10-2018 IM45_1306 b25675506a19a38cbbd0b3cb655412ca 353 SUPERFAMILY SSF111337 1 344 1.14E-129 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 IM45_759 f64e7227da339419879f10c101302576 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 26.057 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_759 f64e7227da339419879f10c101302576 110 Pfam PF00237 Ribosomal protein L22p/L17e 6 107 1.2E-33 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 IM45_759 f64e7227da339419879f10c101302576 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 6.6E-44 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_759 f64e7227da339419879f10c101302576 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_759 f64e7227da339419879f10c101302576 110 SUPERFAMILY SSF54843 1 109 3.92E-39 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_759 f64e7227da339419879f10c101302576 110 Gene3D G3DSA:3.90.470.10 1 110 6.5E-42 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_1302 ff9e055ce77c4a6d546b49b06ae93e6e 80 SUPERFAMILY SSF68989 11 79 1.03E-28 T 12-10-2018 IPR036666 HHA superfamily IM45_1302 ff9e055ce77c4a6d546b49b06ae93e6e 80 Gene3D G3DSA:1.20.1280.40 9 80 5.9E-34 T 12-10-2018 IPR036666 HHA superfamily IM45_1302 ff9e055ce77c4a6d546b49b06ae93e6e 80 Pfam PF05321 Haemolysin expression modulating protein 21 77 2.8E-30 T 12-10-2018 IPR007985 Haemolysin expression modulating, HHA IM45_488 51e908dbeeda28b472c06ccce6a5eac2 239 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 10 230 39.702 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 IM45_488 51e908dbeeda28b472c06ccce6a5eac2 239 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 IM45_488 51e908dbeeda28b472c06ccce6a5eac2 239 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 231 8.3E-73 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 IM45_488 51e908dbeeda28b472c06ccce6a5eac2 239 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 13 229 1.0E-69 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 IM45_488 51e908dbeeda28b472c06ccce6a5eac2 239 Gene3D G3DSA:3.90.550.10 6 238 6.7E-69 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases IM45_488 51e908dbeeda28b472c06ccce6a5eac2 239 SUPERFAMILY SSF53448 11 231 7.15E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases IM45_547 c229de059aa65f9fad5d82665b6894ca 325 TIGRFAM TIGR00510 lipA: lipoyl synthase 28 325 6.8E-141 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 IM45_547 c229de059aa65f9fad5d82665b6894ca 325 Pfam PF04055 Radical SAM superfamily 95 255 1.1E-13 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 IM45_547 c229de059aa65f9fad5d82665b6894ca 325 PIRSF PIRSF005963 2 322 1.4E-128 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 IM45_547 c229de059aa65f9fad5d82665b6894ca 325 SMART SM00729 88 297 3.4E-10 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 IM45_547 c229de059aa65f9fad5d82665b6894ca 325 Gene3D G3DSA:3.20.20.70 84 296 1.5E-18 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_547 c229de059aa65f9fad5d82665b6894ca 325 Hamap MF_00206 Lipoyl synthase [lipA]. 40 325 139.58 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 IM45_547 c229de059aa65f9fad5d82665b6894ca 325 SUPERFAMILY SSF102114 59 319 5.62E-60 T 12-10-2018 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.2E-49 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 Gene3D G3DSA:1.10.8.50 1 71 1.3E-24 T 12-10-2018 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.958 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 SUPERFAMILY SSF46946 2 114 1.1E-42 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 2.4E-30 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 Gene3D G3DSA:4.10.910.10 72 118 7.0E-25 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_793 50679ae5745dd8bd7521e5fe3fc081a3 118 PIRSF PIRSF002134 1 118 9.5E-41 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_1045 fbdc255f3840108429cf8e209b8df514 246 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 8 245 9.1E-88 T 12-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1045 fbdc255f3840108429cf8e209b8df514 246 SMART SM00479 8 185 1.1E-42 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III IM45_1045 fbdc255f3840108429cf8e209b8df514 246 Pfam PF00929 Exonuclease 10 176 6.8E-35 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III IM45_1045 fbdc255f3840108429cf8e209b8df514 246 Gene3D G3DSA:3.30.420.10 1 188 2.2E-58 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 IM45_1045 fbdc255f3840108429cf8e209b8df514 246 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 7 228 2.8E-74 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_1045 fbdc255f3840108429cf8e209b8df514 246 SUPERFAMILY SSF53098 8 184 1.48E-50 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily IM45_453 69c0d98adfadac5562a4566bcfc24b6a 234 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 230 28.521 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD IM45_453 69c0d98adfadac5562a4566bcfc24b6a 234 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 2 230 2.2E-65 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD IM45_453 69c0d98adfadac5562a4566bcfc24b6a 234 Gene3D G3DSA:1.25.40.10 17 233 1.1E-43 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 IM45_453 69c0d98adfadac5562a4566bcfc24b6a 234 Pfam PF13525 Outer membrane lipoprotein 18 223 1.1E-62 T 12-10-2018 IPR039565 Outer membrane lipoprotein BamD-like IM45_783 78b5bb19b811b052fde94dddd03fa922 166 Gene3D G3DSA:3.30.160.20 1 73 1.7E-32 T 12-10-2018 IM45_783 78b5bb19b811b052fde94dddd03fa922 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 11 163 5.4E-70 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 IM45_783 78b5bb19b811b052fde94dddd03fa922 166 SUPERFAMILY SSF54211 79 159 7.33E-27 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_783 78b5bb19b811b052fde94dddd03fa922 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 89 157 2.7E-30 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 IM45_783 78b5bb19b811b052fde94dddd03fa922 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 4 163 33.928 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 IM45_783 78b5bb19b811b052fde94dddd03fa922 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 8.6E-29 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 IM45_783 78b5bb19b811b052fde94dddd03fa922 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site IM45_783 78b5bb19b811b052fde94dddd03fa922 166 Gene3D G3DSA:3.30.230.10 74 166 8.1E-38 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_783 78b5bb19b811b052fde94dddd03fa922 166 SUPERFAMILY SSF54768 9 75 3.03E-23 T 12-10-2018 IM45_944 1bd37ce4079b279936d971265801d4c2 209 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 207 32.654 T 12-10-2018 IPR007451 High frequency lysogenization protein HflD IM45_944 1bd37ce4079b279936d971265801d4c2 209 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 205 1.0E-60 T 12-10-2018 IM45_944 1bd37ce4079b279936d971265801d4c2 209 Gene3D G3DSA:1.10.3890.10 1 209 3.3E-69 T 12-10-2018 IPR035932 HflD-like superfamily IM45_944 1bd37ce4079b279936d971265801d4c2 209 SUPERFAMILY SSF101322 2 207 1.1E-71 T 12-10-2018 IPR035932 HflD-like superfamily IM45_944 1bd37ce4079b279936d971265801d4c2 209 Pfam PF04356 Protein of unknown function (DUF489) 7 199 2.2E-66 T 12-10-2018 IPR007451 High frequency lysogenization protein HflD IM45_1187 f471488b2475485748fbfc38c2b4e8a8 149 Gene3D G3DSA:3.10.129.10 5 148 3.0E-64 T 12-10-2018 IM45_1187 f471488b2475485748fbfc38c2b4e8a8 149 Pfam PF07977 FabA-like domain 17 141 3.0E-38 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_1187 f471488b2475485748fbfc38c2b4e8a8 149 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 8 149 36.814 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_1187 f471488b2475485748fbfc38c2b4e8a8 149 SUPERFAMILY SSF54637 10 147 1.91E-48 T 12-10-2018 IPR029069 HotDog domain superfamily IM45_1187 f471488b2475485748fbfc38c2b4e8a8 149 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 8 146 1.5E-59 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 Gene3D G3DSA:3.30.460.10 193 325 5.0E-43 T 12-10-2018 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 Pfam PF13328 HD domain 26 175 4.0E-51 T 12-10-2018 IPR003607 HD/PDEase domain IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 SUPERFAMILY SSF81301 192 364 1.62E-55 T 12-10-2018 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 457 3.1E-190 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 SUPERFAMILY SSF109604 3 188 6.28E-73 T 12-10-2018 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 SMART SM00954 235 345 1.7E-55 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 SMART SM00471 41 153 2.4E-9 T 12-10-2018 IPR003607 HD/PDEase domain IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 Gene3D G3DSA:1.10.3210.10 3 190 2.0E-77 T 12-10-2018 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 2.2E-31 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 IM45_264 ed5dd08d86c2aa21e23d7b28fcee7ef8 533 Gene3D G3DSA:3.10.20.30 381 454 7.2E-8 T 12-10-2018 IPR012675 Beta-grasp domain superfamily IM45_894 711c4e4ad319413e13fb99350b91b0ad 247 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 243 33.058 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 IM45_894 711c4e4ad319413e13fb99350b91b0ad 247 SUPERFAMILY SSF51366 2 246 1.48E-59 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 IM45_894 711c4e4ad319413e13fb99350b91b0ad 247 Pfam PF00977 Histidine biosynthesis protein 2 236 9.9E-69 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 IM45_894 711c4e4ad319413e13fb99350b91b0ad 247 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 239 7.4E-72 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 IM45_894 711c4e4ad319413e13fb99350b91b0ad 247 Gene3D G3DSA:3.20.20.70 1 247 5.5E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_807 469f4da9ed086c9056ed41e45c50816a 330 PIRSF PIRSF000545 3 319 9.2E-133 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 IM45_807 469f4da9ed086c9056ed41e45c50816a 330 Hamap MF_00215 Pantothenate kinase [coaA]. 1 321 158.864 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 IM45_807 469f4da9ed086c9056ed41e45c50816a 330 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 12 318 1.8E-138 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 IM45_807 469f4da9ed086c9056ed41e45c50816a 330 Gene3D G3DSA:3.40.50.300 11 318 7.9E-82 T 12-10-2018 IM45_807 469f4da9ed086c9056ed41e45c50816a 330 SUPERFAMILY SSF52540 9 318 1.08E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_807 469f4da9ed086c9056ed41e45c50816a 330 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 92 250 1.9E-15 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 IM45_551 29148b4341838440bb3fb9afc3a670f2 187 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 71 2.2E-13 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 IM45_551 29148b4341838440bb3fb9afc3a670f2 187 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 IM45_551 29148b4341838440bb3fb9afc3a670f2 187 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 180 5.0E-52 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 IM45_551 29148b4341838440bb3fb9afc3a670f2 187 PIRSF PIRSF000847 1 187 1.8E-40 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 IM45_551 29148b4341838440bb3fb9afc3a670f2 187 Gene3D G3DSA:1.20.120.1760 4 177 5.3E-14 T 12-10-2018 IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 8.4E-20 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 Gene3D G3DSA:3.10.430.100 61 149 5.2E-29 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 SUPERFAMILY SSF55653 60 149 1.31E-24 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 24.087 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 SUPERFAMILY SSF55658 1 57 1.2E-16 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 8.5E-47 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 147 6.2E-24 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal IM45_1259 66901f693e2b91ca440a2d10fd0ba020 150 Gene3D G3DSA:3.40.5.10 1 49 5.1E-21 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR01900 YidC translocation/secretion protein signature 464 479 1.5E-29 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR01900 YidC translocation/secretion protein signature 484 508 1.5E-29 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR01900 YidC translocation/secretion protein signature 335 351 1.5E-29 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 349 529 5.1E-67 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 458 480 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 214 232 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 155 175 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 411 434 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 495 518 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 66 87 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 247 262 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 PRINTS PR00701 60kDa inner membrane protein signature 320 340 1.8E-97 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 Pfam PF14849 YidC periplasmic domain 61 339 5.9E-74 T 12-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain IM45_319 91220011571d82cace6a0275c10767e1 544 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 348 4.0E-98 T 12-10-2018 IPR028053 Membrane insertase YidC, N-terminal IM45_319 91220011571d82cace6a0275c10767e1 544 Pfam PF02096 60Kd inner membrane protein 350 529 2.1E-58 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 IM45_319 91220011571d82cace6a0275c10767e1 544 Gene3D G3DSA:2.70.98.90 56 329 8.0E-89 T 12-10-2018 IPR038221 YidC, periplasmic domain superfamily IM45_319 91220011571d82cace6a0275c10767e1 544 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 531 25.344 T 12-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 IM45_1310 c9f03571ec157b542ccedfc8359b8260 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 21 102 1.5E-27 T 12-10-2018 IPR003849 Preprotein translocase YajC IM45_1310 c9f03571ec157b542ccedfc8359b8260 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 2.1E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC IM45_1310 c9f03571ec157b542ccedfc8359b8260 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 2.1E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC IM45_1310 c9f03571ec157b542ccedfc8359b8260 110 Pfam PF02699 Preprotein translocase subunit 23 99 4.7E-24 T 12-10-2018 IPR003849 Preprotein translocase YajC IM45_1310 c9f03571ec157b542ccedfc8359b8260 110 SMART SM01323 19 102 5.8E-31 T 12-10-2018 IPR003849 Preprotein translocase YajC IM45_485 40b4ee563a40393b3f7cd6a93b5ae0d0 287 SMART SM00257 80 124 2.5E-8 T 12-10-2018 IPR018392 LysM domain IM45_485 40b4ee563a40393b3f7cd6a93b5ae0d0 287 Pfam PF01476 LysM domain 81 123 7.6E-7 T 12-10-2018 IPR018392 LysM domain IM45_485 40b4ee563a40393b3f7cd6a93b5ae0d0 287 Gene3D G3DSA:3.10.350.10 73 138 9.8E-10 T 12-10-2018 IPR036779 LysM domain superfamily IM45_485 40b4ee563a40393b3f7cd6a93b5ae0d0 287 Pfam PF01551 Peptidase family M23 176 269 2.3E-30 T 12-10-2018 IPR016047 Peptidase M23 IM45_485 40b4ee563a40393b3f7cd6a93b5ae0d0 287 SUPERFAMILY SSF51261 81 273 7.85E-50 T 12-10-2018 IPR011055 Duplicated hybrid motif IM45_485 40b4ee563a40393b3f7cd6a93b5ae0d0 287 Gene3D G3DSA:2.70.70.10 140 274 4.4E-35 T 12-10-2018 IPR011055 Duplicated hybrid motif IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 PIRSF PIRSF001359 13 358 7.0E-89 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 99 111 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 171 182 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 SUPERFAMILY SSF51569 4 356 5.57E-122 T 12-10-2018 IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 Gene3D G3DSA:3.20.20.70 2 358 3.3E-133 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 357 2.1E-103 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 357 7.0E-167 T 12-10-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 IM45_1413 e97b7841328ae83512f97423d82ac3b6 358 Pfam PF01116 Fructose-bisphosphate aldolase class-II 19 354 6.5E-83 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 Gene3D G3DSA:1.10.8.60 145 214 1.1E-20 T 12-10-2018 IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 Pfam PF06144 DNA polymerase III, delta subunit 21 191 3.0E-33 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 Gene3D G3DSA:1.20.272.10 215 343 1.1E-39 T 12-10-2018 IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 333 7.3E-86 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 SUPERFAMILY SSF52540 1 210 1.39E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 SUPERFAMILY SSF48019 213 334 1.7E-29 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 215 337 2.8E-51 T 12-10-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 IM45_536 ef12eca0bd0fddf53948fad0b78fccde 345 Gene3D G3DSA:3.40.50.300 1 141 2.7E-41 T 12-10-2018 IM45_240 53b9add356ab7913a33aacf9d356b129 350 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 29 341 1.5E-112 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 IM45_240 53b9add356ab7913a33aacf9d356b129 350 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 347 67.426 T 12-10-2018 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 IM45_240 53b9add356ab7913a33aacf9d356b129 350 Pfam PF02445 Quinolinate synthetase A protein 34 339 1.1E-98 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 IM45_240 53b9add356ab7913a33aacf9d356b129 350 Gene3D G3DSA:3.40.50.10800 200 295 1.7E-90 T 12-10-2018 IM45_240 53b9add356ab7913a33aacf9d356b129 350 Gene3D G3DSA:3.40.50.10800 33 322 1.7E-90 T 12-10-2018 IM45_240 53b9add356ab7913a33aacf9d356b129 350 Gene3D G3DSA:3.40.50.10800 115 339 1.7E-90 T 12-10-2018 IM45_240 53b9add356ab7913a33aacf9d356b129 350 SUPERFAMILY SSF142754 29 340 9.15E-102 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 IM45_055 2f5d4272d02e7451201489f076b08b81 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 4.1E-95 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 IM45_055 2f5d4272d02e7451201489f076b08b81 225 SUPERFAMILY SSF51366 3 218 4.92E-73 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 IM45_055 2f5d4272d02e7451201489f076b08b81 225 PIRSF PIRSF001461 1 225 2.4E-102 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 IM45_055 2f5d4272d02e7451201489f076b08b81 225 Gene3D G3DSA:3.20.20.70 4 221 3.2E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_055 2f5d4272d02e7451201489f076b08b81 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 6.3E-86 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 IM45_055 2f5d4272d02e7451201489f076b08b81 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 IM45_071 d4b754e004dea109b24ec0b599d935bc 87 PIRSF PIRSF003113 1 86 7.2E-21 T 12-10-2018 IPR002634 BolA protein IM45_071 d4b754e004dea109b24ec0b599d935bc 87 Pfam PF01722 BolA-like protein 22 74 1.9E-12 T 12-10-2018 IPR002634 BolA protein IM45_071 d4b754e004dea109b24ec0b599d935bc 87 SUPERFAMILY SSF82657 1 84 1.05E-25 T 12-10-2018 IPR036065 BolA-like superfamily IM45_071 d4b754e004dea109b24ec0b599d935bc 87 Gene3D G3DSA:3.30.300.90 1 87 2.9E-31 T 12-10-2018 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 13 151 1.4E-58 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 157 67.718 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 28 157 4.0E-49 T 12-10-2018 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 PIRSF PIRSF001399 10 156 1.2E-56 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 ProSitePatterns PS01029 Dehydroquinase class II signature. 17 34 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 Gene3D G3DSA:3.40.50.9100 5 157 3.7E-63 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 Pfam PF01220 Dehydroquinase class II 14 149 5.8E-57 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 IM45_119 6223c3cca4eca928370b9c1ff2d6d0b0 157 SUPERFAMILY SSF52304 13 155 9.81E-59 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 IM45_708 899138bd346acaf315c5e8aee22dcefc 161 SUPERFAMILY SSF47240 1 159 8.8E-52 T 12-10-2018 IPR009078 Ferritin-like superfamily IM45_708 899138bd346acaf315c5e8aee22dcefc 161 Gene3D G3DSA:1.20.1260.10 1 161 8.7E-44 T 12-10-2018 IPR012347 Ferritin-like IM45_708 899138bd346acaf315c5e8aee22dcefc 161 Pfam PF00210 Ferritin-like domain 9 144 2.1E-37 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 IM45_980 aded2c6cbd00c95f6af60698b0750420 836 Pfam PF10150 Ribonuclease E/G family 122 392 1.4E-91 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 IM45_980 aded2c6cbd00c95f6af60698b0750420 836 SMART SM00316 38 120 1.7E-9 T 12-10-2018 IPR022967 RNA-binding domain, S1 IM45_980 aded2c6cbd00c95f6af60698b0750420 836 Gene3D G3DSA:3.40.1260.20 402 511 3.3E-38 T 12-10-2018 IM45_980 aded2c6cbd00c95f6af60698b0750420 836 Pfam PF00575 S1 RNA binding domain 37 119 3.9E-14 T 12-10-2018 IPR003029 S1 domain GO:0003676 IM45_980 aded2c6cbd00c95f6af60698b0750420 836 Hamap MF_00970 Ribonuclease E [rne]. 2 835 31.691 T 12-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 IM45_980 aded2c6cbd00c95f6af60698b0750420 836 Gene3D G3DSA:2.40.50.140 32 126 1.0E-31 T 12-10-2018 IM45_980 aded2c6cbd00c95f6af60698b0750420 836 SUPERFAMILY SSF50249 41 125 8.86E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_980 aded2c6cbd00c95f6af60698b0750420 836 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 426 5.4E-165 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 IM45_1101 5719d06d7b580bd14c146417d5715036 166 SUPERFAMILY SSF160369 4 160 1.7E-42 T 12-10-2018 IM45_1101 5719d06d7b580bd14c146417d5715036 166 Pfam PF00466 Ribosomal protein L10 5 101 3.0E-24 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 IM45_1101 5719d06d7b580bd14c146417d5715036 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 162 23.961 T 12-10-2018 IPR022973 Ribosomal protein L10 IM45_1101 5719d06d7b580bd14c146417d5715036 166 Gene3D G3DSA:3.30.70.1730 1 126 2.7E-32 T 12-10-2018 IM45_706 67051bd8dba35e7f4f7839d78d506fab 211 Pfam PF04352 ProQ/FINO family 8 112 4.9E-38 T 12-10-2018 IPR016103 ProQ/FinO domain IM45_706 67051bd8dba35e7f4f7839d78d506fab 211 SMART SM00945 5 119 3.0E-47 T 12-10-2018 IPR016103 ProQ/FinO domain IM45_706 67051bd8dba35e7f4f7839d78d506fab 211 Hamap MF_00749 RNA chaperone ProQ [proQ]. 2 208 25.801 T 12-10-2018 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 IM45_706 67051bd8dba35e7f4f7839d78d506fab 211 Pfam PF17516 ProQ C-terminal domain 158 206 2.3E-18 T 12-10-2018 IPR035236 RNA chaperone ProQ, C-terminal IM45_706 67051bd8dba35e7f4f7839d78d506fab 211 Gene3D G3DSA:1.10.1710.10 2 121 8.4E-24 T 12-10-2018 IPR036442 ProQ/FinO domain superfamily IM45_706 67051bd8dba35e7f4f7839d78d506fab 211 SUPERFAMILY SSF48657 3 114 5.36E-35 T 12-10-2018 IPR036442 ProQ/FinO domain superfamily IM45_558 82e36c9df9639723e61baac91769e4bd 429 Gene3D G3DSA:3.40.640.10 61 330 6.5E-168 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_558 82e36c9df9639723e61baac91769e4bd 429 Gene3D G3DSA:3.90.1150.10 10 414 6.5E-168 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_558 82e36c9df9639723e61baac91769e4bd 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 242 279 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 IM45_558 82e36c9df9639723e61baac91769e4bd 429 PIRSF PIRSF000521 30 422 2.5E-26 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 IM45_558 82e36c9df9639723e61baac91769e4bd 429 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 424 48.803 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 IM45_558 82e36c9df9639723e61baac91769e4bd 429 SUPERFAMILY SSF53383 1 422 1.92E-128 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_558 82e36c9df9639723e61baac91769e4bd 429 Pfam PF00202 Aminotransferase class-III 27 421 5.1E-120 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 IM45_558 82e36c9df9639723e61baac91769e4bd 429 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 13 421 1.9E-173 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 IM45_1328 d709d147240b27471c4c3fe493eb283e 579 Gene3D G3DSA:3.10.20.310 195 267 5.1E-10 T 12-10-2018 IM45_1328 d709d147240b27471c4c3fe493eb283e 579 Pfam PF17243 POTRA domain TamA domain 1 35 104 7.0E-11 T 12-10-2018 IPR035243 TamA, POTRA domain 1 IM45_1328 d709d147240b27471c4c3fe493eb283e 579 Gene3D G3DSA:3.10.20.310 107 194 1.3E-27 T 12-10-2018 IM45_1328 d709d147240b27471c4c3fe493eb283e 579 Gene3D G3DSA:3.10.20.310 30 106 4.3E-17 T 12-10-2018 IM45_1328 d709d147240b27471c4c3fe493eb283e 579 Gene3D G3DSA:2.40.160.50 268 579 2.0E-102 T 12-10-2018 IM45_1328 d709d147240b27471c4c3fe493eb283e 579 Pfam PF01103 Surface antigen 269 564 1.1E-26 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 73 101 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 Gene3D G3DSA:1.20.5.1030 68 125 3.1E-13 T 12-10-2018 IPR038379 SecE superfamily IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 73 124 1.4E-16 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 72 124 4.2E-14 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 Hamap MF_00422 Protein translocase subunit SecE [secE]. 69 123 11.753 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 PRINTS PR01650 Bacterial translocase SecE signature 67 87 1.9E-27 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 PRINTS PR01650 Bacterial translocase SecE signature 91 111 1.9E-27 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 PRINTS PR01650 Bacterial translocase SecE signature 46 67 1.9E-27 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 IM45_1093 4c0073784b3b6611ecb0a12b8b635d91 129 PRINTS PR01650 Bacterial translocase SecE signature 111 127 1.9E-27 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 IM45_291 48a5625f2923b4a82eeaf2fbdcf12354 241 Pfam PF17154 Gammaproteobacterial periplasmic sensor domain 40 158 2.2E-47 T 12-10-2018 IPR033419 Gammaproteobacterial periplasmic sensor domain GAPES3 IM45_599 dfbcd007e800bdd4193cf0e1e444b1af 129 SUPERFAMILY SSF55298 3 127 9.9E-38 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 IM45_599 dfbcd007e800bdd4193cf0e1e444b1af 129 Gene3D G3DSA:3.30.1330.40 1 128 4.9E-43 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 IM45_599 dfbcd007e800bdd4193cf0e1e444b1af 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 126 7.6E-49 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 IM45_599 dfbcd007e800bdd4193cf0e1e444b1af 129 Pfam PF01042 Endoribonuclease L-PSP 7 127 8.1E-39 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 IM45_299 f00d34b799fe1f9550e4dd0dc0173ac6 650 SUPERFAMILY SSF52540 5 642 7.68E-172 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_299 f00d34b799fe1f9550e4dd0dc0173ac6 650 Gene3D G3DSA:1.10.10.160 114 187 9.6E-98 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily IM45_299 f00d34b799fe1f9550e4dd0dc0173ac6 650 Gene3D G3DSA:3.40.50.300 281 636 6.9E-123 T 12-10-2018 IM45_299 f00d34b799fe1f9550e4dd0dc0173ac6 650 Gene3D G3DSA:3.40.50.300 10 273 9.6E-98 T 12-10-2018 IM45_299 f00d34b799fe1f9550e4dd0dc0173ac6 650 Gene3D G3DSA:1.10.486.10 382 538 6.9E-123 T 12-10-2018 IM45_299 f00d34b799fe1f9550e4dd0dc0173ac6 650 Pfam PF13361 UvrD-like helicase C-terminal domain 277 616 1.5E-72 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 IM45_299 f00d34b799fe1f9550e4dd0dc0173ac6 650 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 271 2.7E-74 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 Gene3D G3DSA:1.10.10.60 8 105 1.8E-32 T 12-10-2018 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 PIRSF PIRSF002097 8 105 2.5E-43 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 SUPERFAMILY SSF46689 11 105 2.01E-24 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 Pfam PF02954 Bacterial regulatory protein, Fis family 62 102 9.5E-14 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 Hamap MF_00166 DNA-binding protein Fis [fis]. 8 105 32.135 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 PRINTS PR01591 DNA-binding protein FIS signature 16 33 3.0E-29 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 PRINTS PR01591 DNA-binding protein FIS signature 49 64 3.0E-29 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 PRINTS PR01591 DNA-binding protein FIS signature 64 76 3.0E-29 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 PRINTS PR01591 DNA-binding protein FIS signature 33 49 3.0E-29 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 68 85 1.7E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 IM45_125 c6d51e70f74646a4be84f69d3837f589 105 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 85 105 1.7E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 IM45_393 83015b97d06d10777e223c3e1869c22b 143 Pfam PF00581 Rhodanese-like domain 43 134 1.1E-15 T 12-10-2018 IPR001763 Rhodanese-like domain IM45_393 83015b97d06d10777e223c3e1869c22b 143 SMART SM00450 40 138 8.7E-17 T 12-10-2018 IPR001763 Rhodanese-like domain IM45_393 83015b97d06d10777e223c3e1869c22b 143 Gene3D G3DSA:3.40.250.10 23 142 4.9E-21 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily IM45_393 83015b97d06d10777e223c3e1869c22b 143 SUPERFAMILY SSF52821 13 141 2.23E-27 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily IM45_950 dbc844253a84357e863e385ea76d59da 233 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 6 225 3.4E-100 T 12-10-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0016020|GO:0044873 IM45_950 dbc844253a84357e863e385ea76d59da 233 Pfam PF00005 ABC transporter 26 174 6.0E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_950 dbc844253a84357e863e385ea76d59da 233 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 IM45_950 dbc844253a84357e863e385ea76d59da 233 SUPERFAMILY SSF52540 6 226 9.58E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_950 dbc844253a84357e863e385ea76d59da 233 SMART SM00382 35 223 5.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_950 dbc844253a84357e863e385ea76d59da 233 Gene3D G3DSA:3.40.50.300 4 228 2.8E-61 T 12-10-2018 IM45_1324 c9086842fa5739712c601f3b8b580147 328 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 138 5.8E-21 T 12-10-2018 IPR016188 PurM-like, N-terminal domain IM45_1324 c9086842fa5739712c601f3b8b580147 328 SUPERFAMILY SSF55326 4 138 1.03E-32 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_1324 c9086842fa5739712c601f3b8b580147 328 Gene3D G3DSA:3.90.650.10 145 322 1.7E-50 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_1324 c9086842fa5739712c601f3b8b580147 328 Gene3D G3DSA:3.30.1330.10 2 144 1.7E-44 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily IM45_1324 c9086842fa5739712c601f3b8b580147 328 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 322 6.2E-107 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 IM45_1324 c9086842fa5739712c601f3b8b580147 328 PIRSF PIRSF005303 1 322 3.2E-83 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 IM45_1324 c9086842fa5739712c601f3b8b580147 328 Pfam PF02769 AIR synthase related protein, C-terminal domain 153 298 1.5E-5 T 12-10-2018 IPR010918 PurM-like, C-terminal domain IM45_1324 c9086842fa5739712c601f3b8b580147 328 SUPERFAMILY SSF56042 143 309 9.42E-35 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily IM45_1324 c9086842fa5739712c601f3b8b580147 328 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 322 27.847 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 IM45_865 2b7fd3bc83a77a8ff2d964f3a7b07d5b 376 Pfam PF00268 Ribonucleotide reductase, small chain 31 332 3.0E-42 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_865 2b7fd3bc83a77a8ff2d964f3a7b07d5b 376 Gene3D G3DSA:1.10.620.20 2 340 1.7E-138 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 IM45_865 2b7fd3bc83a77a8ff2d964f3a7b07d5b 376 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 12-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 IM45_865 2b7fd3bc83a77a8ff2d964f3a7b07d5b 376 SUPERFAMILY SSF47240 3 340 8.45E-107 T 12-10-2018 IPR009078 Ferritin-like superfamily IM45_537 e0cbef57106e49f1178c8858c19f9f3f 211 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 5 211 27.619 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 IM45_537 e0cbef57106e49f1178c8858c19f9f3f 211 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 9 210 4.5E-42 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 IM45_537 e0cbef57106e49f1178c8858c19f9f3f 211 Pfam PF01467 Cytidylyltransferase-like 9 184 8.1E-26 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 IM45_537 e0cbef57106e49f1178c8858c19f9f3f 211 Gene3D G3DSA:3.40.50.620 5 211 5.6E-53 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_537 e0cbef57106e49f1178c8858c19f9f3f 211 SUPERFAMILY SSF52374 7 211 8.76E-47 T 12-10-2018 IM45_537 e0cbef57106e49f1178c8858c19f9f3f 211 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 69 2.0E-9 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 IM45_1409 6f22ff10d8052862ea5b99643022f720 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site IM45_1409 6f22ff10d8052862ea5b99643022f720 323 SUPERFAMILY SSF48576 5 322 9.28E-94 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily IM45_1409 6f22ff10d8052862ea5b99643022f720 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site IM45_1409 6f22ff10d8052862ea5b99643022f720 323 Gene3D G3DSA:1.10.600.10 1 322 4.3E-115 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily IM45_1409 6f22ff10d8052862ea5b99643022f720 323 Pfam PF00348 Polyprenyl synthetase 32 261 1.7E-73 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 12-10-2018 IPR019844 Cold-shock conserved site IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 SUPERFAMILY SSF50249 3 68 9.21E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 PRINTS PR00050 Cold shock protein signature 6 21 1.8E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 PRINTS PR00050 Cold shock protein signature 27 36 1.8E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 PRINTS PR00050 Cold shock protein signature 42 60 1.8E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 SMART SM00357 5 69 5.9E-33 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 Gene3D G3DSA:2.40.50.140 1 69 1.9E-32 T 12-10-2018 IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 2.2E-33 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 IM45_601 3ba70d9578ba20822390a4a4fc5c0554 69 PIRSF PIRSF002599 1 69 6.2E-27 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 IM45_631 012a29d102bd6aebab2eaa4de5169159 300 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site IM45_631 012a29d102bd6aebab2eaa4de5169159 300 SUPERFAMILY SSF48576 4 290 1.38E-85 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily IM45_631 012a29d102bd6aebab2eaa4de5169159 300 Gene3D G3DSA:1.10.600.10 2 300 2.0E-101 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily IM45_631 012a29d102bd6aebab2eaa4de5169159 300 Pfam PF00348 Polyprenyl synthetase 32 272 3.4E-58 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 IM45_631 012a29d102bd6aebab2eaa4de5169159 300 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site IM45_878 38f9ce96e1c15d876685f86ea72348aa 191 SUPERFAMILY SSF54001 67 187 1.54E-35 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily IM45_878 38f9ce96e1c15d876685f86ea72348aa 191 Gene3D G3DSA:3.90.1720.10 62 190 2.6E-37 T 12-10-2018 IM45_878 38f9ce96e1c15d876685f86ea72348aa 191 Pfam PF00877 NlpC/P60 family 79 185 1.5E-26 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain IM45_582 5a1327afebcf87dae92a2477a24161a3 90 SUPERFAMILY SSF47729 1 89 5.15E-29 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 Gene3D G3DSA:4.10.520.10 2 37 1.6E-9 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 Gene3D G3DSA:4.10.520.10 38 90 1.5E-28 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 Pfam PF00216 Bacterial DNA-binding protein 1 89 2.9E-30 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 SMART SM00411 1 89 3.2E-43 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 89 9.3E-46 T 12-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 1.3E-19 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 1.3E-19 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_582 5a1327afebcf87dae92a2477a24161a3 90 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 1.3E-19 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 24 274 1.1E-83 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 SUPERFAMILY SSF53335 4 276 2.04E-55 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 Gene3D G3DSA:3.40.50.150 88 279 4.6E-53 T 12-10-2018 IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 Gene3D G3DSA:1.10.8.10 2 85 2.5E-26 T 12-10-2018 IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 183 189 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 6 278 7.1E-72 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 278 40.79 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 IM45_664 0d4ffef00b1991a2200494dc2e8330b2 280 Pfam PF13847 Methyltransferase domain 112 250 2.4E-15 T 12-10-2018 IPR025714 Methyltransferase domain IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 240 4.2E-43 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 Pfam PF00905 Penicillin binding protein transpeptidase domain 273 610 5.1E-78 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 SUPERFAMILY SSF56519 57 254 5.76E-50 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 20 613 2.7E-231 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 SUPERFAMILY SSF56601 255 613 5.63E-83 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 4 617 50.353 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 Gene3D G3DSA:3.90.1310.10 65 248 1.8E-48 T 12-10-2018 IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 Gene3D G3DSA:3.30.1390.30 86 161 1.8E-48 T 12-10-2018 IM45_541 67dbf379b6024a8fb6e3d2e5d810e6bc 620 Gene3D G3DSA:3.40.710.10 249 619 4.8E-86 T 12-10-2018 IM45_1022 8cc17f3fffe381df03ff571d7b0b0f00 247 Gene3D G3DSA:3.40.50.300 1 247 3.9E-60 T 12-10-2018 IM45_1022 8cc17f3fffe381df03ff571d7b0b0f00 247 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 IM45_1022 8cc17f3fffe381df03ff571d7b0b0f00 247 Pfam PF00005 ABC transporter 18 172 4.0E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_1022 8cc17f3fffe381df03ff571d7b0b0f00 247 SMART SM00382 26 229 3.8E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_1022 8cc17f3fffe381df03ff571d7b0b0f00 247 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 3.9E-108 T 12-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 IM45_1022 8cc17f3fffe381df03ff571d7b0b0f00 247 SUPERFAMILY SSF52540 2 230 5.54E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 Gene3D G3DSA:1.20.5.1150 16 54 1.3E-21 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 3.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 3.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 3.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 3.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 1.5E-23 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 Pfam PF01165 Ribosomal protein S21 4 55 5.3E-22 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 56 2.0E-15 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.871 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1351 70ef9d302cbb6fddcc945d6c8dfcaff6 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 12-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_976 1d303c9c3f21af1d80feb30b67b25905 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 15.456 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_976 1d303c9c3f21af1d80feb30b67b25905 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 9.1E-18 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_976 1d303c9c3f21af1d80feb30b67b25905 56 SUPERFAMILY SSF57829 2 54 4.7E-16 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 IM45_976 1d303c9c3f21af1d80feb30b67b25905 56 Pfam PF01783 Ribosomal L32p protein family 2 55 2.0E-16 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 ProSitePatterns PS00449 ATP synthase a subunit signature. 209 218 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 PRINTS PR00123 ATP synthase A subunit signature 206 228 1.5E-14 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 PRINTS PR00123 ATP synthase A subunit signature 254 269 1.5E-14 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 PRINTS PR00123 ATP synthase A subunit signature 107 123 1.5E-14 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 Gene3D G3DSA:1.20.120.220 98 274 4.0E-63 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 SUPERFAMILY SSF81336 102 267 1.83E-45 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 38 268 7.1E-40 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 Hamap MF_01393 ATP synthase subunit a [atpB]. 23 274 15.838 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_341 2cdc8ee9445870de24d865f07af5764a 276 Pfam PF00119 ATP synthase A chain 49 267 7.9E-52 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_799 72723604015d415ed5670ea67aba9a60 329 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 317 34.128 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 SUPERFAMILY SSF47789 251 324 5.89E-25 T 12-10-2018 IM45_799 72723604015d415ed5670ea67aba9a60 329 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 156 4.7E-21 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 SUPERFAMILY SSF55257 7 233 4.32E-31 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 Gene3D G3DSA:1.10.150.20 244 329 8.9E-37 T 12-10-2018 IM45_799 72723604015d415ed5670ea67aba9a60 329 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 316 3.6E-110 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 SMART SM00662 23 234 8.8E-97 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 Gene3D G3DSA:3.30.1360.10 17 228 5.8E-84 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 256 329 1.0E-33 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 228 3.3E-25 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 Gene3D G3DSA:2.170.120.12 53 177 5.8E-84 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 250 308 1.1E-23 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_799 72723604015d415ed5670ea67aba9a60 329 SUPERFAMILY SSF56553 53 178 9.24E-40 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 IM45_139 4d9f42c036b3d88ee0b4a5a988b0b3d1 222 SMART SM00382 27 214 6.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_139 4d9f42c036b3d88ee0b4a5a988b0b3d1 222 Pfam PF00005 ABC transporter 19 165 9.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_139 4d9f42c036b3d88ee0b4a5a988b0b3d1 222 Gene3D G3DSA:3.40.50.300 1 219 1.1E-54 T 12-10-2018 IM45_139 4d9f42c036b3d88ee0b4a5a988b0b3d1 222 SUPERFAMILY SSF52540 1 216 2.26E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_139 4d9f42c036b3d88ee0b4a5a988b0b3d1 222 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 2.4E-81 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 IM45_972 662586a76360e2d047b5226856faf0c9 293 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 293 1.5E-124 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 IM45_972 662586a76360e2d047b5226856faf0c9 293 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 207 292 3.0E-37 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 IM45_972 662586a76360e2d047b5226856faf0c9 293 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 293 60.623 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 IM45_972 662586a76360e2d047b5226856faf0c9 293 SUPERFAMILY SSF53901 2 293 2.51E-62 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 IM45_972 662586a76360e2d047b5226856faf0c9 293 Gene3D G3DSA:3.40.47.10 1 293 3.2E-109 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 IM45_972 662586a76360e2d047b5226856faf0c9 293 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 82 159 8.7E-25 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 SUPERFAMILY SSF52943 4 287 1.01E-85 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 Pfam PF00231 ATP synthase 5 286 1.2E-85 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 Gene3D G3DSA:3.40.1380.10 61 206 7.3E-99 T 12-10-2018 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 33.803 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 Gene3D G3DSA:1.10.287.80 6 283 7.3E-99 T 12-10-2018 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 2.9E-97 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.4E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 1.4E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.4E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_331 27cb62614958d09e02ef52c4c0aa3884 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 1.4E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_742 6a6d151eeedb9e7efd514f24514f6425 238 SUPERFAMILY SSF161098 7 216 3.53E-34 T 12-10-2018 IPR035906 MetI-like superfamily IM45_742 6a6d151eeedb9e7efd514f24514f6425 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 25 229 2.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 IM45_742 6a6d151eeedb9e7efd514f24514f6425 238 Gene3D G3DSA:1.10.3720.10 3 233 6.5E-41 T 12-10-2018 IPR035906 MetI-like superfamily IM45_515 dce82ebe96e075a327cfb15c1d5a690e 348 SUPERFAMILY SSF109604 55 197 2.48E-38 T 12-10-2018 IM45_515 dce82ebe96e075a327cfb15c1d5a690e 348 Pfam PF13328 HD domain 51 181 3.6E-30 T 12-10-2018 IPR003607 HD/PDEase domain IM45_515 dce82ebe96e075a327cfb15c1d5a690e 348 SUPERFAMILY SSF81301 198 348 1.96E-55 T 12-10-2018 IM45_515 dce82ebe96e075a327cfb15c1d5a690e 348 SMART SM00954 241 348 6.6E-54 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 IM45_515 dce82ebe96e075a327cfb15c1d5a690e 348 Gene3D G3DSA:3.30.460.10 198 331 1.7E-47 T 12-10-2018 IM45_515 dce82ebe96e075a327cfb15c1d5a690e 348 Pfam PF04607 Region found in RelA / SpoT proteins 241 348 1.4E-33 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 IM45_515 dce82ebe96e075a327cfb15c1d5a690e 348 Gene3D G3DSA:1.10.3210.10 29 196 5.7E-35 T 12-10-2018 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 Pfam PF02357 Transcription termination factor nusG 7 112 2.2E-26 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 Gene3D G3DSA:2.30.30.30 122 180 1.6E-25 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 Pfam PF00467 KOW motif 130 162 1.6E-6 T 12-10-2018 IPR005824 KOW IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 180 4.5E-69 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 SUPERFAMILY SSF82679 6 116 5.62E-37 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 Gene3D G3DSA:3.30.70.940 1 121 1.4E-44 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 SMART SM00738 6 115 3.5E-43 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 181 24.03 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 ProSitePatterns PS01014 Transcription termination factor nusG signature. 164 173 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 SMART SM00739 127 154 1.3E-5 T 12-10-2018 IPR005824 KOW IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 SUPERFAMILY SSF50104 125 180 4.41E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 1.9E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 PRINTS PR00338 Transcription termination factor NUSG signature 139 154 1.9E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 IM45_1094 25d736f9bd1cc4f4c480577e7bf82b2a 181 PRINTS PR00338 Transcription termination factor NUSG signature 157 173 1.9E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 IM45_1175 dd9810029488a79cbc303d71574695c0 262 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 1 221 34.365 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 IM45_1175 dd9810029488a79cbc303d71574695c0 262 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 166 183 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 IM45_1175 dd9810029488a79cbc303d71574695c0 262 Pfam PF01255 Putative undecaprenyl diphosphate synthase 1 220 3.2E-73 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 IM45_1175 dd9810029488a79cbc303d71574695c0 262 SUPERFAMILY SSF64005 1 216 1.57E-77 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 IM45_1175 dd9810029488a79cbc303d71574695c0 262 Gene3D G3DSA:3.40.1180.10 1 229 1.5E-80 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 IM45_1175 dd9810029488a79cbc303d71574695c0 262 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 1 220 2.1E-93 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 157 2.5E-73 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 Gene3D G3DSA:3.30.420.10 2 159 3.9E-49 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 1.3E-60 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 12-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 43.174 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 SUPERFAMILY SSF53098 3 156 1.29E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 1.0E-39 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 1.0E-39 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 1.0E-39 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 1.0E-39 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_720 2aca5d66e391f6c8f2a69443c667dbde 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 1.0E-39 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 421 2.2E-140 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 Gene3D G3DSA:3.65.10.10 21 224 3.4E-142 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 426 1.7E-128 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 SUPERFAMILY SSF55205 4 426 2.35E-131 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 Gene3D G3DSA:3.65.10.10 242 421 3.4E-142 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 ProSitePatterns PS00104 EPSP synthase signature 1. 91 105 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 429 32.8 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 IM45_576 7c7057776c021064ebbbf5e6869f5944 431 PIRSF PIRSF000505 3 429 5.8E-141 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 SUPERFAMILY SSF53062 3 129 6.93E-36 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 3 118 4.4E-43 T 12-10-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 SUPERFAMILY SSF52728 159 317 5.49E-55 T 12-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 161 307 1.9E-56 T 12-10-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 Pfam PF03610 PTS system fructose IIA component 5 118 1.7E-30 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 Pfam PF03830 PTS system sorbose subfamily IIB component 161 307 5.5E-54 T 12-10-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 Gene3D G3DSA:3.40.50.510 2 138 1.1E-40 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 IM45_1002 68cdae5a91e5c0ab105c8c995f0c99b2 321 Gene3D G3DSA:3.40.35.10 156 319 1.0E-58 T 12-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 Gene3D G3DSA:1.10.240.10 192 304 3.1E-134 T 12-10-2018 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 Gene3D G3DSA:3.40.50.620 12 335 3.1E-134 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 4.5E-27 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 22 38 4.5E-27 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 4.5E-27 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 72 91 4.5E-27 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 10 336 6.3E-112 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 SUPERFAMILY SSF52374 11 336 7.5E-96 T 12-10-2018 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 Pfam PF00579 tRNA synthetases class I (W and Y) 10 291 2.7E-80 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 18 27 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_053 35d0c1dcc75afec62312f81f6a6d3669 340 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 9 337 41.197 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 SUPERFAMILY SSF54814 2 106 1.1E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 Pfam PF07650 KH domain 38 111 4.0E-18 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.213 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 SUPERFAMILY SSF54821 108 206 1.28E-39 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.1E-98 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 Gene3D G3DSA:3.30.1140.32 108 208 2.7E-44 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 2.1E-40 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 SMART SM00322 60 125 1.3E-8 T 12-10-2018 IPR004087 K Homology domain GO:0003676 IM45_761 614c388be83b5376aa4c46115c5fe29e 232 Gene3D G3DSA:3.30.300.20 17 107 6.3E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 Gene3D G3DSA:2.30.30.100 280 331 8.5E-17 T 12-10-2018 IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 16 329 27.076 T 12-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 Pfam PF03099 Biotin/lipoate A/B protein ligase family 98 222 2.7E-19 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 Pfam PF02237 Biotin protein ligase C terminal domain 282 329 2.5E-6 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 94 329 9.0E-65 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 SUPERFAMILY SSF50037 281 329 9.61E-8 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 Gene3D G3DSA:1.10.10.10 10 77 8.9E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 Gene3D G3DSA:3.30.930.10 78 279 5.3E-65 T 12-10-2018 IM45_1110 a772f732a5f00598576dd5ebcc0cb372 332 SUPERFAMILY SSF55681 87 278 3.23E-52 T 12-10-2018 IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.0E-44 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.2E-17 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.2E-17 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.2E-17 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 25.839 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 SUPERFAMILY SSF54999 5 101 1.96E-34 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 Gene3D G3DSA:3.30.70.600 1 103 3.6E-35 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 SMART SM01403 7 101 4.0E-53 T 12-10-2018 IPR027486 Ribosomal protein S10 domain IM45_747 dd8e12c8a93d51c347e900c474ba0b5b 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.2E-32 T 12-10-2018 IPR027486 Ribosomal protein S10 domain IM45_722 b2b874dc152d96d36239bda594b0110f 239 Gene3D G3DSA:1.10.10.200 1 80 4.8E-30 T 12-10-2018 IPR017856 Integrase-like, N-terminal IM45_722 b2b874dc152d96d36239bda594b0110f 239 SUPERFAMILY SSF75625 3 238 3.01E-80 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_722 b2b874dc152d96d36239bda594b0110f 239 Gene3D G3DSA:3.30.70.980 86 236 5.7E-46 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_722 b2b874dc152d96d36239bda594b0110f 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 31.448 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_722 b2b874dc152d96d36239bda594b0110f 239 Pfam PF01709 Transcriptional regulator 5 237 8.8E-78 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_722 b2b874dc152d96d36239bda594b0110f 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 9.8E-88 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_722 b2b874dc152d96d36239bda594b0110f 239 Gene3D G3DSA:3.30.70.980 130 205 5.7E-46 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_351 63564decc32b91e078e646dfaceb970b 509 SUPERFAMILY SSF50249 16 158 4.71E-43 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_351 63564decc32b91e078e646dfaceb970b 509 SUPERFAMILY SSF55681 165 504 1.09E-112 T 12-10-2018 IM45_351 63564decc32b91e078e646dfaceb970b 509 Gene3D G3DSA:2.40.50.140 18 157 9.4E-39 T 12-10-2018 IM45_351 63564decc32b91e078e646dfaceb970b 509 Pfam PF00152 tRNA synthetases class II (D, K and N) 166 503 2.7E-79 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_351 63564decc32b91e078e646dfaceb970b 509 Gene3D G3DSA:3.30.930.10 158 501 5.8E-125 T 12-10-2018 IM45_351 63564decc32b91e078e646dfaceb970b 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 218 234 1.4E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_351 63564decc32b91e078e646dfaceb970b 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 389 405 1.4E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_351 63564decc32b91e078e646dfaceb970b 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 247 260 1.4E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_351 63564decc32b91e078e646dfaceb970b 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 265 282 1.4E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_351 63564decc32b91e078e646dfaceb970b 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 202 212 1.4E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_351 63564decc32b91e078e646dfaceb970b 509 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 24 506 41.97 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_351 63564decc32b91e078e646dfaceb970b 509 Pfam PF01336 OB-fold nucleic acid binding domain 71 149 4.0E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 IM45_351 63564decc32b91e078e646dfaceb970b 509 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 18 506 2.8E-201 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 Gene3D G3DSA:3.40.50.10490 12 510 7.0E-231 T 12-10-2018 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 524 41.259 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 Pfam PF00342 Phosphoglucose isomerase 52 541 7.0E-241 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 Gene3D G3DSA:1.10.1390.10 511 549 2.9E-18 T 12-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 SUPERFAMILY SSF53697 5 548 1.14E-214 T 12-10-2018 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 Gene3D G3DSA:3.40.50.10490 98 291 7.0E-231 T 12-10-2018 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 338 359 3.1E-55 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 3.1E-55 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 3.1E-55 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 150 169 3.1E-55 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 3.1E-55 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_021 c9233fd9ef765f6e60168aa477d70ace 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 3.1E-55 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 55 227 5.8E-48 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 14 427 3.5E-195 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 175 190 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 SUPERFAMILY SSF142984 252 334 5.62E-22 T 12-10-2018 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 353 364 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 SUPERFAMILY SSF140490 337 429 1.83E-29 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 Gene3D G3DSA:1.20.1440.230 338 437 2.8E-25 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 343 425 3.6E-24 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 SUPERFAMILY SSF142019 16 242 7.59E-84 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 Gene3D G3DSA:3.40.50.11540 60 239 7.7E-77 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 SMART SM00928 340 385 5.0E-21 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_851 22a687f58ff1e0fbac46ea0b2856b73a 451 Gene3D G3DSA:3.10.20.600 244 337 4.0E-28 T 12-10-2018 IM45_109 4a6611501d47cbd78d51c907e0ef8bbe 260 Hamap MF_00443 Thiazole synthase [thiG]. 1 253 42.832 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 IM45_109 4a6611501d47cbd78d51c907e0ef8bbe 260 Gene3D G3DSA:3.20.20.70 1 253 3.1E-108 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_109 4a6611501d47cbd78d51c907e0ef8bbe 260 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 247 2.5E-107 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 IM45_109 4a6611501d47cbd78d51c907e0ef8bbe 260 SUPERFAMILY SSF110399 1 238 5.1E-79 T 12-10-2018 IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 4.1E-30 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 SUPERFAMILY SSF55594 1 82 6.8E-27 T 12-10-2018 IPR035895 HPr-like superfamily IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 Gene3D G3DSA:3.30.1340.10 1 85 9.0E-33 T 12-10-2018 IPR035895 HPr-like superfamily IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.3E-19 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.3E-19 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.3E-19 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like IM45_169 85e91f10cf82d1ce37974da9735ab59c 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 4.9E-27 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Gene3D G3DSA:3.10.20.590 799 860 3.5E-21 T 12-10-2018 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Pfam PF08264 Anticodon-binding domain of tRNA 701 821 1.6E-15 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 SUPERFAMILY SSF52374 4 668 1.09E-141 T 12-10-2018 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 1.2E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 1.2E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 1.2E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 1.2E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 1.2E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 1.2E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 1.2E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Gene3D G3DSA:3.40.50.620 33 566 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 859 22.794 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Gene3D G3DSA:1.10.730.10 8 791 0.0 T 12-10-2018 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 859 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 402 1.0E-69 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Gene3D G3DSA:3.10.330.110 567 628 0.0 T 12-10-2018 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Gene3D G3DSA:3.90.740.10 227 414 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 SUPERFAMILY SSF50677 226 415 3.35E-50 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 618 652 2.6E-7 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 417 572 9.0E-9 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 13 171 8.9E-29 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_533 36c5badceafc796b731a7ea8cb7769d7 860 SUPERFAMILY SSF47323 662 859 1.08E-35 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 IM45_451 cda90e6591e42ec91d684ccd730c57da 331 Gene3D G3DSA:3.20.20.70 1 331 8.1E-143 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_451 cda90e6591e42ec91d684ccd730c57da 331 SUPERFAMILY SSF51569 2 329 1.99E-123 T 12-10-2018 IM45_451 cda90e6591e42ec91d684ccd730c57da 331 PIRSF PIRSF001361 1 331 1.2E-150 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 IM45_451 cda90e6591e42ec91d684ccd730c57da 331 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 2 330 2.5E-150 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 IM45_451 cda90e6591e42ec91d684ccd730c57da 331 Pfam PF00793 DAHP synthetase I family 26 324 4.5E-92 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 IM45_1304 1596ef5e10ed24207ecad40be7ff7662 200 Pfam PF00578 AhpC/TSA family 5 139 2.6E-35 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 IM45_1304 1596ef5e10ed24207ecad40be7ff7662 200 SUPERFAMILY SSF52833 1 195 9.2E-65 T 12-10-2018 IPR036249 Thioredoxin-like superfamily IM45_1304 1596ef5e10ed24207ecad40be7ff7662 200 Gene3D G3DSA:3.40.30.10 1 197 6.5E-71 T 12-10-2018 IM45_1304 1596ef5e10ed24207ecad40be7ff7662 200 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 195 2.9E-13 T 12-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 IM45_1304 1596ef5e10ed24207ecad40be7ff7662 200 PIRSF PIRSF000239 1 199 2.9E-59 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 IM45_121 85f507edea1da29fcac9dd3bddea0059 150 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 150 3.6E-52 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 IM45_121 85f507edea1da29fcac9dd3bddea0059 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 111 124 4.9E-15 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 IM45_121 85f507edea1da29fcac9dd3bddea0059 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 96 110 4.9E-15 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 IM45_121 85f507edea1da29fcac9dd3bddea0059 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 79 92 4.9E-15 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 IM45_121 85f507edea1da29fcac9dd3bddea0059 150 Pfam PF00364 Biotin-requiring enzyme 77 149 1.3E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment IM45_121 85f507edea1da29fcac9dd3bddea0059 150 Gene3D G3DSA:2.40.50.100 71 150 1.0E-26 T 12-10-2018 IM45_121 85f507edea1da29fcac9dd3bddea0059 150 SUPERFAMILY SSF51230 74 150 7.2E-23 T 12-10-2018 IPR011053 Single hybrid motif IM45_819 4c033734d98684d0762e010335f87f73 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 8 244 7.4E-74 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_819 4c033734d98684d0762e010335f87f73 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 7 249 34.134 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_819 4c033734d98684d0762e010335f87f73 267 Gene3D G3DSA:3.30.70.660 111 248 8.1E-47 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 IM45_819 4c033734d98684d0762e010335f87f73 267 SUPERFAMILY SSF55120 8 260 5.61E-90 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_819 4c033734d98684d0762e010335f87f73 267 PIRSF PIRSF001430 6 260 3.4E-73 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_819 4c033734d98684d0762e010335f87f73 267 Pfam PF01416 tRNA pseudouridine synthase 150 250 6.9E-26 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_819 4c033734d98684d0762e010335f87f73 267 Pfam PF01416 tRNA pseudouridine synthase 14 108 5.4E-9 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_819 4c033734d98684d0762e010335f87f73 267 Gene3D G3DSA:3.30.70.580 5 110 2.3E-39 T 12-10-2018 IM45_045 985f24e78afcddae519d87c848917377 545 Pfam PF03109 ABC1 family 113 231 9.8E-35 T 12-10-2018 IPR004147 UbiB domain IM45_045 985f24e78afcddae519d87c848917377 545 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 7 444 4.4E-175 T 12-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 IM45_045 985f24e78afcddae519d87c848917377 545 SUPERFAMILY SSF56112 94 437 6.93E-46 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily IM45_045 985f24e78afcddae519d87c848917377 545 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 541 55.167 T 12-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 IM45_252 6457bad75988946281d8c43c3e7b8bd3 148 SUPERFAMILY SSF50249 4 148 6.51E-56 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_252 6457bad75988946281d8c43c3e7b8bd3 148 Hamap MF_00984 Single-stranded DNA-binding protein. 6 117 38.213 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 IM45_252 6457bad75988946281d8c43c3e7b8bd3 148 Pfam PF00436 Single-strand binding protein family 6 112 9.9E-43 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 IM45_252 6457bad75988946281d8c43c3e7b8bd3 148 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 130 7.3E-54 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 IM45_252 6457bad75988946281d8c43c3e7b8bd3 148 Gene3D G3DSA:2.40.50.140 1 115 1.2E-50 T 12-10-2018 IM45_252 6457bad75988946281d8c43c3e7b8bd3 148 PIRSF PIRSF002070 2 146 8.8E-40 T 12-10-2018 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 Pfam PF13396 Phospholipase_D-nuclease N-terminal 17 59 4.2E-7 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal IM45_700 c28b07dc33fe52c9189eb51855feb503 485 Hamap MF_00190 Cardiolipin synthase A [clsA]. 2 485 48.735 T 12-10-2018 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 Gene3D G3DSA:3.30.870.10 111 311 2.5E-32 T 12-10-2018 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 Gene3D G3DSA:3.30.870.10 314 458 2.7E-24 T 12-10-2018 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 6 485 9.2E-184 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 SUPERFAMILY SSF56024 274 472 4.26E-46 T 12-10-2018 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 Pfam PF13091 PLD-like domain 134 242 1.1E-10 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 Pfam PF13091 PLD-like domain 326 446 2.1E-22 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 SUPERFAMILY SSF56024 77 314 2.69E-45 T 12-10-2018 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 SMART SM00155 398 425 1.7E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 IM45_700 c28b07dc33fe52c9189eb51855feb503 485 SMART SM00155 219 246 6.3E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 IM45_1177 0f2fcdcb22ac18b38911ee5c37afd08b 249 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 203 229 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 IM45_1177 0f2fcdcb22ac18b38911ee5c37afd08b 249 Pfam PF01148 Cytidylyltransferase family 2 242 1.7E-62 T 12-10-2018 IM45_1242 dc6256f14c80096940a78c004ce8d858 331 Gene3D G3DSA:3.40.718.10 1 330 1.5E-118 T 12-10-2018 IM45_1242 dc6256f14c80096940a78c004ce8d858 331 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 325 2.7E-122 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 IM45_1242 dc6256f14c80096940a78c004ce8d858 331 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 4 329 34.662 T 12-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 IM45_1242 dc6256f14c80096940a78c004ce8d858 331 SUPERFAMILY SSF53659 4 329 7.36E-108 T 12-10-2018 IM45_1242 dc6256f14c80096940a78c004ce8d858 331 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 321 1.2E-101 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 IM45_519 3bdd3f81fd0bf084f20583644e63c2cc 114 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 95 112 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 IM45_519 3bdd3f81fd0bf084f20583644e63c2cc 114 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 114 35.234 T 12-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 IM45_519 3bdd3f81fd0bf084f20583644e63c2cc 114 Pfam PF01521 Iron-sulphur cluster biosynthesis 9 109 1.8E-17 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 IM45_519 3bdd3f81fd0bf084f20583644e63c2cc 114 Gene3D G3DSA:2.60.300.12 9 114 6.9E-33 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 IM45_519 3bdd3f81fd0bf084f20583644e63c2cc 114 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 113 1.3E-37 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 IM45_519 3bdd3f81fd0bf084f20583644e63c2cc 114 SUPERFAMILY SSF89360 3 100 1.96E-29 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 IM45_447 aefb62c8ce4ba2b2060b665d29710500 112 Pfam PF04219 Protein of unknown function, DUF 10 98 3.4E-38 T 12-10-2018 IPR007335 Protein of unknown function DUF413 IM45_085 1dae10a035db19e7949bb676024cf498 80 Gene3D G3DSA:2.60.450.10 1 62 3.0E-18 T 12-10-2018 IM45_085 1dae10a035db19e7949bb676024cf498 80 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 1 54 1.6E-12 T 12-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related IM45_085 1dae10a035db19e7949bb676024cf498 80 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 1 53 1.6E-12 T 12-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 Hamap MF_01454 GTPase Obg [obg]. 2 335 45.928 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 3.1E-140 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 Gene3D G3DSA:3.40.50.300 159 341 9.6E-49 T 12-10-2018 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 SUPERFAMILY SSF82051 2 157 2.22E-54 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily IM45_1403 69a1e90638769264e0d314c65a0bd818 356 Pfam PF01018 GTP1/OBG 4 157 1.9E-56 T 12-10-2018 IPR006169 GTP1/OBG domain IM45_1403 69a1e90638769264e0d314c65a0bd818 356 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 8.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 8.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 8.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 8.4E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 PIRSF PIRSF002401 1 354 1.1E-137 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type IM45_1403 69a1e90638769264e0d314c65a0bd818 356 Gene3D G3DSA:2.70.210.12 1 158 1.1E-58 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily IM45_1403 69a1e90638769264e0d314c65a0bd818 356 Pfam PF01926 50S ribosome-binding GTPase 161 284 1.7E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 IM45_1403 69a1e90638769264e0d314c65a0bd818 356 SUPERFAMILY SSF52540 152 341 8.18E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1063 62b92d08b213e56b5c9833416f6583f3 142 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 139 23.524 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 IM45_1063 62b92d08b213e56b5c9833416f6583f3 142 SMART SM00732 4 104 4.5E-34 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 IM45_1063 62b92d08b213e56b5c9833416f6583f3 142 SUPERFAMILY SSF53098 5 138 2.58E-40 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily IM45_1063 62b92d08b213e56b5c9833416f6583f3 142 Pfam PF03652 Holliday junction resolvase 5 136 9.3E-40 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 IM45_1063 62b92d08b213e56b5c9833416f6583f3 142 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 136 8.8E-47 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 IM45_1063 62b92d08b213e56b5c9833416f6583f3 142 Gene3D G3DSA:3.30.420.140 3 138 1.6E-41 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 Gene3D G3DSA:3.10.290.10 7 75 1.4E-15 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 310 9.4E-99 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 Pfam PF01479 S4 domain 18 63 7.8E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 SUPERFAMILY SSF55120 77 314 5.76E-72 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 SMART SM00363 18 83 3.8E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 Pfam PF00849 RNA pseudouridylate synthase 92 241 1.0E-30 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 SUPERFAMILY SSF55174 18 69 3.36E-9 T 12-10-2018 IM45_455 bd8cca07e76a5a7a89f4477668f75368 320 Gene3D G3DSA:3.30.2350.10 84 314 2.0E-68 T 12-10-2018 IM45_493 d819af1df91fae4f4d949c387a1a0bd9 210 Pfam PF01583 Adenylylsulphate kinase 32 184 4.0E-67 T 12-10-2018 IM45_493 d819af1df91fae4f4d949c387a1a0bd9 210 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 15 198 4.3E-78 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 IM45_493 d819af1df91fae4f4d949c387a1a0bd9 210 Gene3D G3DSA:3.40.50.300 10 206 3.2E-72 T 12-10-2018 IM45_493 d819af1df91fae4f4d949c387a1a0bd9 210 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 31 202 36.47 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 IM45_493 d819af1df91fae4f4d949c387a1a0bd9 210 SUPERFAMILY SSF52540 28 200 2.3E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_809 6ec93c02bf2cff3c699109328cbb5a90 156 SUPERFAMILY SSF53254 1 141 2.21E-19 T 12-10-2018 IPR029033 Histidine phosphatase superfamily IM45_809 6ec93c02bf2cff3c699109328cbb5a90 156 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 79 7.1E-9 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 IM45_809 6ec93c02bf2cff3c699109328cbb5a90 156 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 154 1.1E-39 T 12-10-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 IM45_809 6ec93c02bf2cff3c699109328cbb5a90 156 Gene3D G3DSA:3.40.50.1240 1 156 2.2E-35 T 12-10-2018 IPR029033 Histidine phosphatase superfamily IM45_809 6ec93c02bf2cff3c699109328cbb5a90 156 SMART SM00855 2 116 0.0049 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 IM45_698 7d19bd13d29ca38453d8ac0550397319 99 Pfam PF03795 YCII-related domain 27 92 1.6E-7 T 12-10-2018 IPR005545 YCII-related IM45_698 7d19bd13d29ca38453d8ac0550397319 99 SUPERFAMILY SSF54909 27 98 6.17E-8 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel IM45_698 7d19bd13d29ca38453d8ac0550397319 99 Gene3D G3DSA:3.30.70.1060 1 99 2.2E-14 T 12-10-2018 IM45_629 bdeb83d6aa10d3479fb390f8b83ad6b6 97 SUPERFAMILY SSF52821 18 96 1.44E-11 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily IM45_629 bdeb83d6aa10d3479fb390f8b83ad6b6 97 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 3 95 1.8E-38 T 12-10-2018 IPR026340 Thiazole biosynthesis domain GO:0052837 KEGG: 00730+2.8.1.4 IM45_629 bdeb83d6aa10d3479fb390f8b83ad6b6 97 Gene3D G3DSA:3.40.250.10 6 97 4.7E-10 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily IM45_1322 32efd19ddf5815c9923a4e45d5cffba1 139 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 4 135 22.672 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 IM45_1322 32efd19ddf5815c9923a4e45d5cffba1 139 Gene3D G3DSA:1.10.940.10 1 139 2.3E-49 T 12-10-2018 IPR035926 NusB-like superfamily IM45_1322 32efd19ddf5815c9923a4e45d5cffba1 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 6 133 4.7E-43 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 IM45_1322 32efd19ddf5815c9923a4e45d5cffba1 139 SUPERFAMILY SSF48013 4 137 1.22E-41 T 12-10-2018 IPR035926 NusB-like superfamily IM45_1322 32efd19ddf5815c9923a4e45d5cffba1 139 Pfam PF01029 NusB family 7 130 2.1E-34 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 IM45_473 8f38c5be26bfb0d28b1fb2de72126d62 61 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 9.6E-31 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 IM45_473 8f38c5be26bfb0d28b1fb2de72126d62 61 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 56 17.11 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 IM45_473 8f38c5be26bfb0d28b1fb2de72126d62 61 SUPERFAMILY SSF117130 1 54 8.76E-21 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 IM45_473 8f38c5be26bfb0d28b1fb2de72126d62 61 Pfam PF02599 Global regulator protein family 1 52 5.8E-27 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 IM45_473 8f38c5be26bfb0d28b1fb2de72126d62 61 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 3.0E-20 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 IM45_473 8f38c5be26bfb0d28b1fb2de72126d62 61 Gene3D G3DSA:3.30.70.1680 1 61 1.4E-30 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 IM45_1021 f43b171fbf10bba11aca7709ab910d9e 432 SUPERFAMILY SSF101960 30 425 8.11E-90 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily IM45_1021 f43b171fbf10bba11aca7709ab910d9e 432 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 135 409 5.6E-72 T 12-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 IM45_1021 f43b171fbf10bba11aca7709ab910d9e 432 Pfam PF01458 Uncharacterized protein family (UPF0051) 173 398 1.5E-62 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 IM45_1169 eb9f1625f82bd4a82486007c9b10eea3 249 SUPERFAMILY SSF53633 5 238 2.36E-66 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily IM45_1169 eb9f1625f82bd4a82486007c9b10eea3 249 Hamap MF_01220_B Uridylate kinase [pyrH]. 5 238 41.617 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 IM45_1169 eb9f1625f82bd4a82486007c9b10eea3 249 Gene3D G3DSA:3.40.1160.10 2 245 4.3E-71 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily IM45_1169 eb9f1625f82bd4a82486007c9b10eea3 249 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 7 238 3.7E-100 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 IM45_1169 eb9f1625f82bd4a82486007c9b10eea3 249 Pfam PF00696 Amino acid kinase family 9 217 2.6E-24 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 IM45_1169 eb9f1625f82bd4a82486007c9b10eea3 249 PIRSF PIRSF005650 2 247 5.7E-86 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 IM45_315 85139ad37b99a593f9a6e48d700c2d1d 105 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 104 12.697 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 IM45_315 85139ad37b99a593f9a6e48d700c2d1d 105 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 94 2.0E-35 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 IM45_315 85139ad37b99a593f9a6e48d700c2d1d 105 Gene3D G3DSA:3.30.230.10 1 105 2.2E-37 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_315 85139ad37b99a593f9a6e48d700c2d1d 105 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 6 102 2.2E-30 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 IM45_315 85139ad37b99a593f9a6e48d700c2d1d 105 SUPERFAMILY SSF54211 1 103 1.11E-27 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_315 85139ad37b99a593f9a6e48d700c2d1d 105 Pfam PF00825 Ribonuclease P 1 100 9.3E-30 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 IM45_315 85139ad37b99a593f9a6e48d700c2d1d 105 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 45 59 - T 12-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 Pfam PF00364 Biotin-requiring enzyme 4 73 9.9E-19 T 12-10-2018 IPR000089 Biotin/lipoyl attachment IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 Gene3D G3DSA:3.30.559.10 165 410 6.5E-86 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 SUPERFAMILY SSF51230 1 78 5.37E-20 T 12-10-2018 IPR011053 Single hybrid motif IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 Gene3D G3DSA:2.40.50.100 3 78 2.8E-19 T 12-10-2018 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 Pfam PF02817 e3 binding domain 111 146 5.9E-14 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 SUPERFAMILY SSF52777 170 409 6.67E-71 T 12-10-2018 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 SUPERFAMILY SSF47005 106 150 1.83E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 182 409 4.6E-72 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 IM45_1119 2362c61992cbbbbe2ba534f26888e3b7 410 Gene3D G3DSA:4.10.320.10 111 155 9.9E-19 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 IM45_1273 63c7cdf2dd8d7db5354fcff350b339b8 342 Gene3D G3DSA:3.30.479.30 53 161 3.2E-10 T 12-10-2018 IM45_1273 63c7cdf2dd8d7db5354fcff350b339b8 342 SUPERFAMILY SSF117892 56 158 1.83E-15 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily IM45_1273 63c7cdf2dd8d7db5354fcff350b339b8 342 PIRSF PIRSF005651 1 338 1.2E-99 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 IM45_1273 63c7cdf2dd8d7db5354fcff350b339b8 342 SMART SM00244 18 230 6.5E-38 T 12-10-2018 IPR001107 Band 7 domain IM45_1273 63c7cdf2dd8d7db5354fcff350b339b8 342 Pfam PF01145 SPFH domain / Band 7 family 22 246 2.8E-31 T 12-10-2018 IPR001107 Band 7 domain IM45_1273 63c7cdf2dd8d7db5354fcff350b339b8 342 SUPERFAMILY SSF117892 185 236 8.11E-9 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily IM45_1273 63c7cdf2dd8d7db5354fcff350b339b8 342 TIGRFAM TIGR01932 hflC: HflC protein 1 330 1.5E-129 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 IM45_041 3c2ce42c1a59cfcb8b9e367a7d4b1be7 252 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 37 52 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 IM45_041 3c2ce42c1a59cfcb8b9e367a7d4b1be7 252 Pfam PF01209 ubiE/COQ5 methyltransferase family 18 251 6.1E-99 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 IM45_041 3c2ce42c1a59cfcb8b9e367a7d4b1be7 252 SUPERFAMILY SSF53335 25 250 1.35E-50 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_041 3c2ce42c1a59cfcb8b9e367a7d4b1be7 252 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 26 251 7.1E-87 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 IM45_041 3c2ce42c1a59cfcb8b9e367a7d4b1be7 252 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 159 173 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 IM45_041 3c2ce42c1a59cfcb8b9e367a7d4b1be7 252 Gene3D G3DSA:3.40.50.150 32 252 2.0E-73 T 12-10-2018 IM45_041 3c2ce42c1a59cfcb8b9e367a7d4b1be7 252 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 17 251 38.102 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 Gene3D G3DSA:2.60.15.10 9 96 1.1E-30 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 SUPERFAMILY SSF46604 94 143 4.97E-12 T 12-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 11 139 1.4E-43 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 Gene3D G3DSA:1.20.5.440 97 140 5.1E-14 T 12-10-2018 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 SUPERFAMILY SSF51344 10 92 7.85E-24 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 13 90 1.1E-28 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 9 137 20.365 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 16 96 6.0E-36 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 IM45_327 1c88ed61525bbd6a2cbb27fa59ae5e5b 145 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 95 139 1.9E-8 T 12-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain IM45_910 b528ab9d72147b41e5b54d71e0334f65 209 Pfam PF00753 Metallo-beta-lactamase superfamily 10 192 8.9E-30 T 12-10-2018 IPR001279 Metallo-beta-lactamase IM45_910 b528ab9d72147b41e5b54d71e0334f65 209 SMART SM00849 12 192 7.8E-35 T 12-10-2018 IPR001279 Metallo-beta-lactamase IM45_910 b528ab9d72147b41e5b54d71e0334f65 209 Gene3D G3DSA:3.60.15.10 1 209 9.7E-70 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like IM45_910 b528ab9d72147b41e5b54d71e0334f65 209 SUPERFAMILY SSF56281 1 209 6.98E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like IM45_187 4a6a4229d02bec953134c9312e2f6845 276 Gene3D G3DSA:1.10.3720.10 15 272 3.3E-68 T 12-10-2018 IPR035906 MetI-like superfamily IM45_187 4a6a4229d02bec953134c9312e2f6845 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 274 1.2E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 IM45_187 4a6a4229d02bec953134c9312e2f6845 276 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 7 269 4.1E-108 T 12-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 IM45_187 4a6a4229d02bec953134c9312e2f6845 276 SUPERFAMILY SSF161098 17 266 1.05E-55 T 12-10-2018 IPR035906 MetI-like superfamily IM45_187 4a6a4229d02bec953134c9312e2f6845 276 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 9 271 1.7E-111 T 12-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 136 4.5E-7 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 Gene3D G3DSA:1.10.8.60 336 441 3.8E-39 T 12-10-2018 IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 SMART SM00382 49 333 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 SUPERFAMILY SSF52540 3 442 2.11E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 444 42.904 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 SMART SM01086 336 435 2.3E-17 T 12-10-2018 IPR019489 Clp ATPase, C-terminal IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 444 3.1E-225 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 IM45_379 18077b5cf1c0e639a1a761ae0d395e53 444 Pfam PF07724 AAA domain (Cdc48 subfamily) 188 330 1.1E-42 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 PIRSF PIRSF004640 1 364 6.8E-143 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 Pfam PF04551 GcpE protein 13 354 1.4E-127 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 364 33.774 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 Gene3D G3DSA:3.30.413.10 262 361 1.6E-21 T 12-10-2018 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 Gene3D G3DSA:3.20.20.20 1 261 2.1E-102 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 SUPERFAMILY SSF51412 25 132 1.37E-8 T 12-10-2018 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 SUPERFAMILY SSF56014 266 339 4.58E-10 T 12-10-2018 IM45_015 4a0e7d833d972cd97a7d13b9cefa98b8 373 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 350 3.2E-122 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 IM45_465 7f9e4576992f31a57b48241345c9d18c 80 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 12-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_465 7f9e4576992f31a57b48241345c9d18c 80 SUPERFAMILY SSF54565 1 76 1.12E-28 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_465 7f9e4576992f31a57b48241345c9d18c 80 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 80 1.7E-29 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_465 7f9e4576992f31a57b48241345c9d18c 80 Pfam PF00886 Ribosomal protein S16 8 68 4.6E-24 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_465 7f9e4576992f31a57b48241345c9d18c 80 Gene3D G3DSA:3.30.1320.10 1 80 8.4E-31 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_465 7f9e4576992f31a57b48241345c9d18c 80 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 23.472 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Gene3D G3DSA:3.10.20.310 181 270 5.2E-22 T 12-10-2018 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Pfam PF07244 Surface antigen variable number repeat 287 350 3.6E-5 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Pfam PF07244 Surface antigen variable number repeat 182 269 2.6E-14 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Pfam PF07244 Surface antigen variable number repeat 354 427 1.6E-12 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Pfam PF07244 Surface antigen variable number repeat 99 178 7.3E-7 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 30 812 9.5E-254 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Pfam PF01103 Surface antigen 454 812 9.9E-83 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Gene3D G3DSA:3.10.20.310 271 351 5.9E-9 T 12-10-2018 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Gene3D G3DSA:3.10.20.310 25 97 8.0E-17 T 12-10-2018 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Gene3D G3DSA:2.40.160.50 432 812 6.0E-122 T 12-10-2018 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 9 812 23.315 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Gene3D G3DSA:3.10.20.310 98 179 4.2E-11 T 12-10-2018 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 Gene3D G3DSA:3.10.20.310 353 431 2.6E-22 T 12-10-2018 IM45_1180 d728b862b024b7f1931cb3e9486d6eed 812 PIRSF PIRSF006076 3 812 3.7E-221 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 SMART SM00883 2 95 1.6E-45 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 PRINTS PR00297 10kDa chaperonin signature 60 72 8.5E-27 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 PRINTS PR00297 10kDa chaperonin signature 25 46 8.5E-27 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 PRINTS PR00297 10kDa chaperonin signature 3 18 8.5E-27 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 PRINTS PR00297 10kDa chaperonin signature 82 95 8.5E-27 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 Gene3D G3DSA:2.30.33.40 1 97 2.1E-35 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 22.905 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 SUPERFAMILY SSF50129 1 96 1.65E-29 T 12-10-2018 IPR011032 GroES-like superfamily IM45_1297 1e9c3927b268b99322a2a5da5e985c19 97 Pfam PF00166 Chaperonin 10 Kd subunit 2 95 3.2E-29 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 IM45_1195 54876e6ac49a68f3dd6ebff7d0be8f46 398 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 394 3.4E-108 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 IM45_1195 54876e6ac49a68f3dd6ebff7d0be8f46 398 Gene3D G3DSA:3.90.1150.10 262 398 1.1E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_1195 54876e6ac49a68f3dd6ebff7d0be8f46 398 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 205 219 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 IM45_1195 54876e6ac49a68f3dd6ebff7d0be8f46 398 Gene3D G3DSA:3.40.640.10 5 261 1.7E-63 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_1195 54876e6ac49a68f3dd6ebff7d0be8f46 398 PIRSF PIRSF001434 3 398 7.7E-108 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 IM45_1195 54876e6ac49a68f3dd6ebff7d0be8f46 398 SUPERFAMILY SSF53383 31 395 1.36E-82 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_1195 54876e6ac49a68f3dd6ebff7d0be8f46 398 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 11 397 6.9E-162 T 12-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 IM45_407 138dfe26ef5d12bb70beed84efc98dae 82 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 3.6E-26 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_407 138dfe26ef5d12bb70beed84efc98dae 82 Pfam PF00830 Ribosomal L28 family 3 62 3.7E-24 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_407 138dfe26ef5d12bb70beed84efc98dae 82 SUPERFAMILY SSF143800 1 75 6.87E-27 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_407 138dfe26ef5d12bb70beed84efc98dae 82 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.423 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_407 138dfe26ef5d12bb70beed84efc98dae 82 Gene3D G3DSA:2.30.170.40 2 78 1.0E-28 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 PIRSF PIRSF002191 1 114 1.6E-47 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 SUPERFAMILY SSF50104 2 113 1.7E-43 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily IM45_459 2dd74a421dfe84886377e77c427c295d 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 112 5.4E-49 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 113 28.098 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 PRINTS PR00061 Ribosomal protein L19 signature 33 62 2.6E-35 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 PRINTS PR00061 Ribosomal protein L19 signature 87 112 2.6E-35 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 PRINTS PR00061 Ribosomal protein L19 signature 3 32 2.6E-35 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 Pfam PF01245 Ribosomal protein L19 3 112 3.3E-46 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_459 2dd74a421dfe84886377e77c427c295d 114 Gene3D G3DSA:2.30.30.790 4 114 3.2E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_481 4e59ef45ea6e190a7aed23dbdbf1dd84 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 205 2.5E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 IM45_481 4e59ef45ea6e190a7aed23dbdbf1dd84 219 SUPERFAMILY SSF161098 14 201 4.19E-42 T 12-10-2018 IPR035906 MetI-like superfamily IM45_481 4e59ef45ea6e190a7aed23dbdbf1dd84 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 110 1.6E-30 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 IM45_481 4e59ef45ea6e190a7aed23dbdbf1dd84 219 Gene3D G3DSA:1.10.3720.10 8 218 1.5E-47 T 12-10-2018 IPR035906 MetI-like superfamily IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 290 4.8E-80 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 Gene3D G3DSA:1.20.1640.10 104 307 4.9E-15 T 12-10-2018 IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 301 26.496 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 Pfam PF02355 Protein export membrane protein 115 298 1.0E-63 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 115 287 4.0E-51 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 PRINTS PR01755 Bacterial translocase SecF protein signature 206 224 2.8E-30 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 PRINTS PR01755 Bacterial translocase SecF protein signature 158 172 2.8E-30 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 PRINTS PR01755 Bacterial translocase SecF protein signature 238 253 2.8E-30 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 2.8E-30 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 SUPERFAMILY SSF82866 115 298 6.67E-36 T 12-10-2018 IM45_1314 a514a025e730dd9a8a16fd8d5b720814 315 Pfam PF07549 SecD/SecF GG Motif 41 66 1.8E-9 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site IM45_226 2bfb2864a0c59ff697d1e10a022babed 87 Gene3D G3DSA:3.40.50.261 1 41 2.7E-9 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 IM45_226 2bfb2864a0c59ff697d1e10a022babed 87 SUPERFAMILY SSF52210 1 77 5.86E-6 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 IM45_857 57d3d397f01d8db4f230c1747d2caa4b 128 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 123 1.3E-29 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_857 57d3d397f01d8db4f230c1747d2caa4b 128 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 124 19.664 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 IM45_857 57d3d397f01d8db4f230c1747d2caa4b 128 Gene3D G3DSA:1.20.58.1610 1 124 4.5E-38 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 SUPERFAMILY SSF54211 597 772 3.79E-57 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 SUPERFAMILY SSF88697 11 203 6.46E-50 T 12-10-2018 IPR015947 PUA-like superfamily IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 PIRSF PIRSF001174 1 777 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 597 613 5.4E-56 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 705 724 5.4E-56 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 728 746 5.4E-56 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 5.4E-56 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 675 694 5.4E-56 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Gene3D G3DSA:1.10.8.60 493 586 6.3E-31 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 SMART SM00464 12 204 3.4E-79 T 12-10-2018 IPR003111 Lon, substrate-binding domain IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 SUPERFAMILY SSF52540 315 589 2.3E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Gene3D G3DSA:2.30.130.40 1 119 1.7E-35 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 9.3E-18 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Gene3D G3DSA:1.20.58.1480 122 247 7.7E-47 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Gene3D G3DSA:3.30.230.10 587 774 1.6E-83 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 SMART SM00382 350 494 5.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 678 686 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 572 774 2.7E-95 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 12 203 2.4E-41 T 12-10-2018 IPR003111 Lon, substrate-binding domain IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Hamap MF_01973 Lon protease [lon]. 13 774 70.126 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 Gene3D G3DSA:3.40.50.300 316 492 1.5E-60 T 12-10-2018 IM45_605 b4a922a07528ecc9e981376cfc6390b5 790 TIGRFAM TIGR00763 lon: endopeptidase La 14 773 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 437 1.8E-191 T 12-10-2018 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 SUPERFAMILY SSF102114 125 374 3.14E-61 T 12-10-2018 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 Pfam PF04055 Radical SAM superfamily 151 325 4.4E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 SMART SM00729 147 367 2.2E-56 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 Pfam PF01938 TRAM domain 379 437 7.1E-15 T 12-10-2018 IPR002792 TRAM domain IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 Gene3D G3DSA:3.40.50.12160 3 136 4.7E-28 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 Gene3D G3DSA:3.80.30.20 145 377 7.2E-81 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 2.4E-25 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 68.071 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 IM45_157 ea45e992fdac0bbc29635f2305ccb082 445 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 3.3E-145 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 IM45_1279 2fbd9ba376984d233f39d607da2ac74b 301 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 1 285 2.0E-107 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 IM45_1279 2fbd9ba376984d233f39d607da2ac74b 301 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 1 294 25.506 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 IM45_1279 2fbd9ba376984d233f39d607da2ac74b 301 Gene3D G3DSA:1.10.20.140 104 175 7.6E-98 T 12-10-2018 IM45_1279 2fbd9ba376984d233f39d607da2ac74b 301 Pfam PF01715 IPP transferase 31 276 1.1E-76 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 IM45_1279 2fbd9ba376984d233f39d607da2ac74b 301 Gene3D G3DSA:3.40.50.300 1 281 7.6E-98 T 12-10-2018 IM45_1279 2fbd9ba376984d233f39d607da2ac74b 301 SUPERFAMILY SSF52540 1 142 5.58E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 757 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 Gene3D G3DSA:3.20.20.210 388 755 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 Gene3D G3DSA:3.20.20.210 7 523 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 312 7.9E-121 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 PIRSF PIRSF000382 2 759 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 SUPERFAMILY SSF51726 4 392 1.7E-106 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 9.5E-155 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 SUPERFAMILY SSF51726 395 757 2.22E-116 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 IM45_037 6aa192e690bdd3a1e5218ac7bad967d3 759 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 757 36.71 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 IM45_135 f263cfce851e45f91209913a5f89534e 96 SUPERFAMILY SSF64307 11 81 7.85E-23 T 12-10-2018 IPR036868 TusA-like domain superfamily IM45_135 f263cfce851e45f91209913a5f89534e 96 Pfam PF01206 Sulfurtransferase TusA 13 81 1.8E-22 T 12-10-2018 IPR001455 TusA-like domain IM45_135 f263cfce851e45f91209913a5f89534e 96 Gene3D G3DSA:3.30.110.40 3 83 4.6E-27 T 12-10-2018 IPR036868 TusA-like domain superfamily IM45_135 f263cfce851e45f91209913a5f89534e 96 Hamap MF_00413 Sulfur carrier protein TusA [tusA]. 5 83 26.51 T 12-10-2018 IPR022931 Sulfur carrier protein TusA GO:0002143|GO:0097163 IM45_189 87bf7354454d4daf9bd08535ddad0718 288 SUPERFAMILY SSF161098 16 268 1.44E-49 T 12-10-2018 IPR035906 MetI-like superfamily IM45_189 87bf7354454d4daf9bd08535ddad0718 288 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 16 275 3.3E-101 T 12-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 IM45_189 87bf7354454d4daf9bd08535ddad0718 288 Gene3D G3DSA:1.10.3720.10 20 276 2.7E-55 T 12-10-2018 IPR035906 MetI-like superfamily IM45_189 87bf7354454d4daf9bd08535ddad0718 288 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 19 276 1.9E-108 T 12-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 IM45_189 87bf7354454d4daf9bd08535ddad0718 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 266 8.5E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 IM45_771 a61fed95a6897c7054879287d8acfee7 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 2.3E-32 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_771 a61fed95a6897c7054879287d8acfee7 104 Pfam PF00467 KOW motif 8 29 6.2E-5 T 12-10-2018 IPR005824 KOW IM45_771 a61fed95a6897c7054879287d8acfee7 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 103 4.9E-18 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_771 a61fed95a6897c7054879287d8acfee7 104 SUPERFAMILY SSF50104 4 102 1.34E-27 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily IM45_771 a61fed95a6897c7054879287d8acfee7 104 Gene3D G3DSA:2.30.30.30 2 104 9.0E-31 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 IM45_771 a61fed95a6897c7054879287d8acfee7 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 16.288 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_771 a61fed95a6897c7054879287d8acfee7 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_274 f25e5040decc88ff65aa613b011c8da7 109 SUPERFAMILY SSF82607 11 102 6.8E-33 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily IM45_274 f25e5040decc88ff65aa613b011c8da7 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 101 8.5E-37 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family IM45_274 f25e5040decc88ff65aa613b011c8da7 109 PIRSF PIRSF004555 4 107 2.8E-35 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family IM45_274 f25e5040decc88ff65aa613b011c8da7 109 Pfam PF02575 YbaB/EbfC DNA-binding family 11 99 3.5E-31 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family IM45_274 f25e5040decc88ff65aa613b011c8da7 109 Gene3D G3DSA:3.30.1310.10 1 109 2.2E-39 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily IM45_274 f25e5040decc88ff65aa613b011c8da7 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 96 21.591 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family IM45_413 7a77b9c11f30dcd3b7e021621bd6be43 153 SUPERFAMILY SSF51283 1 152 1.96E-50 T 12-10-2018 IPR036157 dUTPase-like superfamily IM45_413 7a77b9c11f30dcd3b7e021621bd6be43 153 TIGRFAM TIGR00576 dut: dUTP diphosphatase 10 152 2.5E-44 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 IM45_413 7a77b9c11f30dcd3b7e021621bd6be43 153 Gene3D G3DSA:2.70.40.10 1 152 7.2E-49 T 12-10-2018 IPR036157 dUTPase-like superfamily IM45_413 7a77b9c11f30dcd3b7e021621bd6be43 153 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 152 32.408 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 IM45_413 7a77b9c11f30dcd3b7e021621bd6be43 153 Pfam PF00692 dUTPase 16 151 6.6E-39 T 12-10-2018 IPR029054 dUTPase-like IM45_1027 c7050200a12ea5b9fd1ba615575cd97b 132 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 IM45_1027 c7050200a12ea5b9fd1ba615575cd97b 132 SUPERFAMILY SSF89360 20 113 7.72E-27 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 IM45_1027 c7050200a12ea5b9fd1ba615575cd97b 132 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 123 3.5E-30 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 IM45_1027 c7050200a12ea5b9fd1ba615575cd97b 132 Pfam PF01521 Iron-sulphur cluster biosynthesis 20 119 4.8E-16 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 IM45_1027 c7050200a12ea5b9fd1ba615575cd97b 132 Gene3D G3DSA:2.60.300.12 19 124 1.2E-31 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 IM45_775 806c95ad61d25fd6b6138bd523879843 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.351 T 12-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid IM45_775 806c95ad61d25fd6b6138bd523879843 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 2.5E-25 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_775 806c95ad61d25fd6b6138bd523879843 101 SUPERFAMILY SSF57716 2 101 1.28E-36 T 12-10-2018 IM45_775 806c95ad61d25fd6b6138bd523879843 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_775 806c95ad61d25fd6b6138bd523879843 101 Gene3D G3DSA:4.10.830.10 41 101 6.1E-23 T 12-10-2018 IM45_795 21dfa5bb8b591623110252c0544b589a 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 6.7E-56 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_795 21dfa5bb8b591623110252c0544b589a 129 Pfam PF00411 Ribosomal protein S11 19 128 7.6E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 IM45_795 21dfa5bb8b591623110252c0544b589a 129 PIRSF PIRSF002131 1 129 4.0E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 IM45_795 21dfa5bb8b591623110252c0544b589a 129 SUPERFAMILY SSF53137 15 129 1.63E-48 T 12-10-2018 IM45_795 21dfa5bb8b591623110252c0544b589a 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 9 129 32.507 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 IM45_795 21dfa5bb8b591623110252c0544b589a 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site IM45_795 21dfa5bb8b591623110252c0544b589a 129 Gene3D G3DSA:3.30.420.80 1 129 2.5E-56 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_244 f82ddc9b1d807fa84a59a892d5df7f8b 549 Pfam PF00999 Sodium/hydrogen exchanger family 8 420 5.4E-77 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 IM45_244 f82ddc9b1d807fa84a59a892d5df7f8b 549 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 545 5.6E-194 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 IM45_1142 5d0fc3a9ee28e2b4c77770347e11896a 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 348 372 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1142 5d0fc3a9ee28e2b4c77770347e11896a 403 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 32 399 40.975 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1142 5d0fc3a9ee28e2b4c77770347e11896a 403 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 34 389 3.8E-132 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_1142 5d0fc3a9ee28e2b4c77770347e11896a 403 Pfam PF01098 Cell cycle protein 37 390 2.0E-121 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 IM45_586 c424f8d7c49e278688f0836e98242640 174 SUPERFAMILY SSF52540 90 160 4.32E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_586 c424f8d7c49e278688f0836e98242640 174 SUPERFAMILY SSF90123 3 85 2.09E-10 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 IM45_586 c424f8d7c49e278688f0836e98242640 174 Pfam PF00005 ABC transporter 117 164 6.8E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 IM45_586 c424f8d7c49e278688f0836e98242640 174 Gene3D G3DSA:3.40.50.300 87 170 3.5E-16 T 12-10-2018 IM45_586 c424f8d7c49e278688f0836e98242640 174 Gene3D G3DSA:1.20.1560.10 1 86 1.6E-13 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 Gene3D G3DSA:3.40.50.300 4 210 3.9E-74 T 12-10-2018 IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 Pfam PF00271 Helicase conserved C-terminal domain 232 340 6.3E-29 T 12-10-2018 IPR001650 Helicase, C-terminal IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 Gene3D G3DSA:3.40.50.300 211 435 5.1E-49 T 12-10-2018 IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 Pfam PF03880 DbpA RNA binding domain 470 539 3.6E-19 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 SUPERFAMILY SSF52540 74 361 1.11E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 SMART SM00490 259 340 1.0E-30 T 12-10-2018 IPR001650 Helicase, C-terminal IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 Gene3D G3DSA:3.30.70.330 468 541 4.3E-9 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 1 541 45.238 T 12-10-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 Pfam PF00270 DEAD/DEAH box helicase 31 195 2.3E-49 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 IM45_1373 fa91a3e0a09ac45d052491207d001cc0 587 SMART SM00487 25 223 2.0E-62 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 Gene3D G3DSA:3.40.50.1860 109 224 4.3E-79 T 12-10-2018 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 SUPERFAMILY SSF53681 123 239 5.07E-27 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 197 207 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 Gene3D G3DSA:3.40.50.1860 21 243 4.3E-79 T 12-10-2018 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 SUPERFAMILY SSF53681 18 120 6.21E-29 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 TIGRFAM TIGR00067 glut_race: glutamate racemase 19 267 2.6E-66 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 Pfam PF01177 Asp/Glu/Hydantoin racemase 22 232 2.3E-21 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 84 92 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_353 194d1a7e7c9975378331d8d1c7c01bdd 283 Hamap MF_00258 Glutamate racemase [murI]. 17 274 30.889 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 IM45_395 b361f15e6ed1b2150e4b2385364b118a 391 Gene3D G3DSA:2.70.70.10 265 391 4.9E-34 T 12-10-2018 IPR011055 Duplicated hybrid motif IM45_395 b361f15e6ed1b2150e4b2385364b118a 391 Pfam PF01551 Peptidase family M23 294 385 7.0E-27 T 12-10-2018 IPR016047 Peptidase M23 IM45_395 b361f15e6ed1b2150e4b2385364b118a 391 SUPERFAMILY SSF51261 202 389 1.29E-41 T 12-10-2018 IPR011055 Duplicated hybrid motif IM45_686 bac488f2b39dbc8b7db200933fd91d22 104 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 1 94 18.686 T 12-10-2018 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 IM45_686 bac488f2b39dbc8b7db200933fd91d22 104 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 85 2.6E-13 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 IM45_1171 6547a468fe363a84ca84fb70bcb8cda4 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 184 2.3E-67 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 IM45_1171 6547a468fe363a84ca84fb70bcb8cda4 185 SUPERFAMILY SSF55194 2 184 2.09E-63 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 IM45_1171 6547a468fe363a84ca84fb70bcb8cda4 185 Gene3D G3DSA:1.10.132.20 12 182 2.6E-61 T 12-10-2018 IM45_1171 6547a468fe363a84ca84fb70bcb8cda4 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 25.607 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 IM45_1171 6547a468fe363a84ca84fb70bcb8cda4 185 Pfam PF01765 Ribosome recycling factor 20 182 1.1E-54 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 IM45_1171 6547a468fe363a84ca84fb70bcb8cda4 185 Gene3D G3DSA:3.30.1360.40 31 105 2.6E-61 T 12-10-2018 IM45_167 2cb26eff0591a676464eacb293b207d4 322 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 312 1.3E-143 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 IM45_167 2cb26eff0591a676464eacb293b207d4 322 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 IM45_167 2cb26eff0591a676464eacb293b207d4 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 300 9.6E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme IM45_167 2cb26eff0591a676464eacb293b207d4 322 Gene3D G3DSA:3.40.50.1100 43 145 4.5E-123 T 12-10-2018 IM45_167 2cb26eff0591a676464eacb293b207d4 322 SUPERFAMILY SSF53686 3 315 2.36E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme IM45_167 2cb26eff0591a676464eacb293b207d4 322 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 312 1.2E-135 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 IM45_167 2cb26eff0591a676464eacb293b207d4 322 Gene3D G3DSA:3.40.50.1100 12 307 4.5E-123 T 12-10-2018 IM45_1041 4e1f54db120b102978c16c03443be378 174 Gene3D G3DSA:3.30.110.10 76 172 9.6E-40 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 IM45_1041 4e1f54db120b102978c16c03443be378 174 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 76 2.0E-27 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 IM45_1041 4e1f54db120b102978c16c03443be378 174 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 170 2.1E-70 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 IM45_1041 4e1f54db120b102978c16c03443be378 174 SUPERFAMILY SSF54364 6 78 4.58E-26 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 IM45_1041 4e1f54db120b102978c16c03443be378 174 SUPERFAMILY SSF55200 82 172 1.19E-34 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 IM45_1041 4e1f54db120b102978c16c03443be378 174 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 IM45_1041 4e1f54db120b102978c16c03443be378 174 Gene3D G3DSA:3.10.20.80 2 75 1.3E-28 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 IM45_1041 4e1f54db120b102978c16c03443be378 174 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 83 169 3.4E-37 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 IM45_1041 4e1f54db120b102978c16c03443be378 174 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 171 29.079 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 IM45_961 e9a84becfa8cfe70acaf2494dc408596 214 SUPERFAMILY SSF52540 1 211 1.11E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_961 e9a84becfa8cfe70acaf2494dc408596 214 Pfam PF02223 Thymidylate kinase 8 199 4.9E-49 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 IM45_961 e9a84becfa8cfe70acaf2494dc408596 214 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 199 3.2E-56 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 IM45_961 e9a84becfa8cfe70acaf2494dc408596 214 Gene3D G3DSA:3.40.50.300 1 211 5.2E-57 T 12-10-2018 IM45_961 e9a84becfa8cfe70acaf2494dc408596 214 ProSitePatterns PS01331 Thymidylate kinase signature. 95 107 - T 12-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 IM45_961 e9a84becfa8cfe70acaf2494dc408596 214 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 26.536 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 IM45_1049 0ca7efff8746acb194f2a1421f850779 235 SUPERFAMILY SSF53335 82 209 3.09E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_1049 0ca7efff8746acb194f2a1421f850779 235 Gene3D G3DSA:3.40.50.150 56 211 1.1E-12 T 12-10-2018 IM45_1049 0ca7efff8746acb194f2a1421f850779 235 Pfam PF08241 Methyltransferase domain 82 130 4.4E-6 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 IM45_039 c9ea688ef4c661f1bd2eb0140db4ce91 519 Pfam PF02646 RmuC family 189 483 2.9E-102 T 12-10-2018 IPR003798 DNA recombination RmuC IM45_1421 81e22a00b8589503a354acd14e172dbc 389 SUPERFAMILY SSF51905 4 379 1.61E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1421 81e22a00b8589503a354acd14e172dbc 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 2.2E-12 T 12-10-2018 IM45_1421 81e22a00b8589503a354acd14e172dbc 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.2E-12 T 12-10-2018 IM45_1421 81e22a00b8589503a354acd14e172dbc 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.2E-12 T 12-10-2018 IM45_1421 81e22a00b8589503a354acd14e172dbc 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 2.2E-12 T 12-10-2018 IM45_1421 81e22a00b8589503a354acd14e172dbc 389 Gene3D G3DSA:3.30.9.50 79 268 6.1E-90 T 12-10-2018 IM45_1421 81e22a00b8589503a354acd14e172dbc 389 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 4 385 4.6E-127 T 12-10-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 IM45_1421 81e22a00b8589503a354acd14e172dbc 389 Gene3D G3DSA:3.50.50.60 4 337 6.1E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1421 81e22a00b8589503a354acd14e172dbc 389 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 385 2.3E-111 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 IM45_1421 81e22a00b8589503a354acd14e172dbc 389 Pfam PF01494 FAD binding domain 3 345 1.5E-21 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 IM45_232 d3435ba6a61a48d0b9262ee38aaf36e1 232 SUPERFAMILY SSF74653 146 232 1.96E-17 T 12-10-2018 IM45_232 d3435ba6a61a48d0b9262ee38aaf36e1 232 TIGRFAM TIGR02794 tolA_full: protein TolA 71 231 1.6E-25 T 12-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 IM45_232 d3435ba6a61a48d0b9262ee38aaf36e1 232 Pfam PF06519 TolA C-terminal 139 229 2.0E-27 T 12-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 IM45_232 d3435ba6a61a48d0b9262ee38aaf36e1 232 Gene3D G3DSA:3.30.1150.10 143 232 1.1E-27 T 12-10-2018 IM45_1397 c5db9c136cf89672fe7f9eecfaa40325 209 Pfam PF01728 FtsJ-like methyltransferase 31 207 1.1E-54 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 IM45_1397 c5db9c136cf89672fe7f9eecfaa40325 209 PIRSF PIRSF005461 1 209 2.2E-78 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 IM45_1397 c5db9c136cf89672fe7f9eecfaa40325 209 SUPERFAMILY SSF53335 31 207 5.16E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_1397 c5db9c136cf89672fe7f9eecfaa40325 209 Gene3D G3DSA:3.40.50.150 30 208 3.3E-59 T 12-10-2018 IM45_1397 c5db9c136cf89672fe7f9eecfaa40325 209 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 15 208 27.788 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 SMART SM01004 5 323 1.7E-187 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 PIRSF PIRSF001415 1 325 4.6E-135 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 Pfam PF00490 Delta-aminolevulinic acid dehydratase 8 321 3.4E-125 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 SUPERFAMILY SSF51569 5 321 1.9E-121 T 12-10-2018 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 153 172 1.7E-51 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 123 137 1.7E-51 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 1.7E-51 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 191 210 1.7E-51 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 1.7E-51 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 1.7E-51 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 IM45_939 7bf9a8b635101c58a5d556b452cc131b 325 Gene3D G3DSA:3.20.20.70 6 324 3.6E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 SUPERFAMILY SSF51905 5 387 4.9E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 Gene3D G3DSA:3.50.50.60 259 407 2.3E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 Gene3D G3DSA:3.50.50.60 3 211 1.8E-68 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 393 6.5E-120 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.1E-16 T 12-10-2018 IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 2.1E-16 T 12-10-2018 IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.1E-16 T 12-10-2018 IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.1E-16 T 12-10-2018 IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 297 310 - T 12-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 IM45_1423 c7514b2f9082f2ad474e5d1fdc1c2e1b 407 Pfam PF01494 FAD binding domain 6 348 2.0E-23 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 IM45_1047 616abf63bdade9e2b3773bd12fcf7059 154 SUPERFAMILY SSF53098 3 142 2.91E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily IM45_1047 616abf63bdade9e2b3773bd12fcf7059 154 Hamap MF_00042 Ribonuclease H [rnhA]. 2 148 30.416 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 IM45_1047 616abf63bdade9e2b3773bd12fcf7059 154 Pfam PF00075 RNase H 3 140 1.4E-42 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 IM45_1047 616abf63bdade9e2b3773bd12fcf7059 154 Gene3D G3DSA:3.30.420.10 1 153 1.1E-49 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 PIRSF PIRSF000094 1 260 1.3E-118 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 4.1E-81 T 12-10-2018 IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 6 8.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 8.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 SUPERFAMILY SSF51735 6 253 3.01E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_678 3338f51ad3b9002e6a3bc10b7aedf9ed 260 Gene3D G3DSA:3.40.50.720 1 260 4.0E-58 T 12-10-2018 IM45_1417 d3b9c724e8e1b23be436fb30c1f67b69 198 SUPERFAMILY SSF100950 7 196 5.16E-50 T 12-10-2018 IPR037171 NagB/RpiA transferase-like IM45_1417 d3b9c724e8e1b23be436fb30c1f67b69 198 Gene3D G3DSA:3.40.50.10420 3 195 8.5E-51 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily IM45_1417 d3b9c724e8e1b23be436fb30c1f67b69 198 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 7 190 2.0E-48 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase IM45_1417 d3b9c724e8e1b23be436fb30c1f67b69 198 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 8 190 2.7E-42 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase IM45_1417 d3b9c724e8e1b23be436fb30c1f67b69 198 PIRSF PIRSF006806 2 192 3.5E-36 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase IM45_1137 9b663bcbd985fc5d7a0b594c42143908 240 Gene3D G3DSA:3.40.50.11690 100 235 7.3E-42 T 12-10-2018 IM45_1137 9b663bcbd985fc5d7a0b594c42143908 240 Pfam PF03799 Cell division protein FtsQ 103 220 2.8E-21 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB IM45_1137 9b663bcbd985fc5d7a0b594c42143908 240 Pfam PF08478 POTRA domain, FtsQ-type 30 99 2.1E-17 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type IM45_1137 9b663bcbd985fc5d7a0b594c42143908 240 Gene3D G3DSA:3.10.20.310 31 99 1.6E-26 T 12-10-2018 IM45_1137 9b663bcbd985fc5d7a0b594c42143908 240 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 6 228 19.826 T 12-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 IM45_1287 5a1c7f5f583716b86f0056f43d6a1ecf 206 Gene3D G3DSA:3.30.420.10 17 204 1.2E-69 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 IM45_1287 5a1c7f5f583716b86f0056f43d6a1ecf 206 SUPERFAMILY SSF53098 23 202 1.21E-48 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily IM45_1287 5a1c7f5f583716b86f0056f43d6a1ecf 206 Hamap MF_00045 Oligoribonuclease [orn]. 25 203 43.835 T 12-10-2018 IPR022894 Oligoribonuclease GO:0000175 IM45_1287 5a1c7f5f583716b86f0056f43d6a1ecf 206 SMART SM00479 29 202 4.1E-18 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III IM45_1287 5a1c7f5f583716b86f0056f43d6a1ecf 206 Pfam PF00929 Exonuclease 31 192 3.9E-32 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III IM45_301 e62770d1aaffc792ef0f5461207627a2 337 SUPERFAMILY SSF143865 20 276 8.63E-39 T 12-10-2018 IM45_301 e62770d1aaffc792ef0f5461207627a2 337 Gene3D G3DSA:1.20.58.340 261 337 2.3E-25 T 12-10-2018 IM45_301 e62770d1aaffc792ef0f5461207627a2 337 SUPERFAMILY SSF144083 272 334 1.24E-20 T 12-10-2018 IM45_301 e62770d1aaffc792ef0f5461207627a2 337 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 24 337 2.2E-102 T 12-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 IM45_301 e62770d1aaffc792ef0f5461207627a2 337 Pfam PF01544 CorA-like Mg2+ transporter protein 48 333 2.9E-55 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 IM45_248 80f4e9146b4f3fae3b877c65346663b0 293 SUPERFAMILY SSF81345 8 269 1.15E-23 T 12-10-2018 IPR037294 ABC transporter, BtuC-like IM45_248 80f4e9146b4f3fae3b877c65346663b0 293 Pfam PF00950 ABC 3 transport family 12 271 1.5E-54 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 IM45_855 65da289b3368f9c01a43000968b21a6c 221 SUPERFAMILY SSF56770 40 186 1.96E-62 T 12-10-2018 IM45_855 65da289b3368f9c01a43000968b21a6c 221 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 24 178 41.619 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_855 65da289b3368f9c01a43000968b21a6c 221 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 145 161 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_855 65da289b3368f9c01a43000968b21a6c 221 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 43 179 1.8E-67 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_855 65da289b3368f9c01a43000968b21a6c 221 Gene3D G3DSA:3.40.50.12280 22 190 8.0E-68 T 12-10-2018 IM45_855 65da289b3368f9c01a43000968b21a6c 221 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 65 171 9.9E-21 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_043 d0ced10768b0afa2dd1118bce363d14e 160 Pfam PF02036 SCP-2 sterol transfer family 1 75 1.3E-4 T 12-10-2018 IPR003033 SCP2 sterol-binding domain IM45_733 440eb844f343c590e08eceaf707ab253 668 Gene3D G3DSA:3.40.50.300 377 664 3.3E-110 T 12-10-2018 IM45_733 440eb844f343c590e08eceaf707ab253 668 SUPERFAMILY SSF52540 359 652 1.24E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_733 440eb844f343c590e08eceaf707ab253 668 SMART SM00382 415 601 0.0015 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_733 440eb844f343c590e08eceaf707ab253 668 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 3 158 8.0E-29 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region IM45_733 440eb844f343c590e08eceaf707ab253 668 Pfam PF01580 FtsK/SpoIIIE family 380 580 2.4E-61 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 IM45_733 440eb844f343c590e08eceaf707ab253 668 Gene3D G3DSA:3.30.980.40 272 376 7.5E-31 T 12-10-2018 IM45_912 c0b406731ccb615aa846b58e926a1038 396 Gene3D G3DSA:3.40.640.10 45 315 8.9E-149 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_912 c0b406731ccb615aa846b58e926a1038 396 Pfam PF00155 Aminotransferase class I and II 28 392 5.7E-80 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 IM45_912 c0b406731ccb615aa846b58e926a1038 396 Gene3D G3DSA:3.90.1150.10 12 391 8.9E-149 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_912 c0b406731ccb615aa846b58e926a1038 396 SUPERFAMILY SSF53383 1 396 1.27E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_912 c0b406731ccb615aa846b58e926a1038 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 IM45_912 c0b406731ccb615aa846b58e926a1038 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 2.3E-35 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 IM45_912 c0b406731ccb615aa846b58e926a1038 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 2.3E-35 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 IM45_912 c0b406731ccb615aa846b58e926a1038 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 2.3E-35 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 IM45_912 c0b406731ccb615aa846b58e926a1038 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 2.3E-35 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 IM45_489 2705ac9cf38d94224fa58a7e98936ea5 108 Hamap MF_00599 Cell division protein FtsB [ftsB]. 6 95 32.774 T 12-10-2018 IPR023081 Cell division protein FtsB IM45_489 2705ac9cf38d94224fa58a7e98936ea5 108 Pfam PF04977 Septum formation initiator 16 94 3.2E-26 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC IM45_489 2705ac9cf38d94224fa58a7e98936ea5 108 Gene3D G3DSA:1.20.5.400 27 68 5.1E-8 T 12-10-2018 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 502 3.4E-133 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 SUPERFAMILY SSF81442 43 557 6.67E-176 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 636 0.0 T 12-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 Gene3D G3DSA:1.20.210.10 52 552 5.7E-187 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 2.3E-93 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_617 92351e71a125c2b8ae916c8bd8e4f9af 646 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 IM45_365 f13efd51d8b08f054feb515e08988c56 373 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 300 329 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site IM45_365 f13efd51d8b08f054feb515e08988c56 373 Gene3D G3DSA:3.40.1350.30 45 190 8.6E-125 T 12-10-2018 IM45_365 f13efd51d8b08f054feb515e08988c56 373 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 367 38.96 T 12-10-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 IM45_365 f13efd51d8b08f054feb515e08988c56 373 Gene3D G3DSA:3.40.50.150 14 362 8.6E-125 T 12-10-2018 IM45_365 f13efd51d8b08f054feb515e08988c56 373 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 349 359 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site IM45_365 f13efd51d8b08f054feb515e08988c56 373 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 10 367 2.1E-158 T 12-10-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 IM45_365 f13efd51d8b08f054feb515e08988c56 373 SUPERFAMILY SSF53335 6 366 9.52E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_365 f13efd51d8b08f054feb515e08988c56 373 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 10 367 1.9E-161 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 IM45_175 78dc064207086108a094ad04b9e66976 237 SUPERFAMILY SSF56104 2 232 3.6E-71 T 12-10-2018 IM45_175 78dc064207086108a094ad04b9e66976 237 Gene3D G3DSA:3.30.200.20 8 231 2.6E-84 T 12-10-2018 IM45_175 78dc064207086108a094ad04b9e66976 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 233 1.7E-69 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 IM45_175 78dc064207086108a094ad04b9e66976 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_175 78dc064207086108a094ad04b9e66976 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_175 78dc064207086108a094ad04b9e66976 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 27.7 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_175 78dc064207086108a094ad04b9e66976 237 Pfam PF01259 SAICAR synthetase 7 231 6.3E-54 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 IM45_175 78dc064207086108a094ad04b9e66976 237 Gene3D G3DSA:3.30.470.20 85 220 2.6E-84 T 12-10-2018 IM45_924 4c775c10a16b5d9c23e52bce56449854 108 PIRSF PIRSF006223 1 108 2.9E-44 T 12-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE IM45_924 4c775c10a16b5d9c23e52bce56449854 108 Gene3D G3DSA:3.30.1420.10 1 37 2.6E-7 T 12-10-2018 IM45_924 4c775c10a16b5d9c23e52bce56449854 108 Gene3D G3DSA:1.10.10.370 38 108 3.8E-29 T 12-10-2018 IM45_924 4c775c10a16b5d9c23e52bce56449854 108 Pfam PF04358 DsrC like protein 3 108 2.1E-42 T 12-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE IM45_924 4c775c10a16b5d9c23e52bce56449854 108 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 1 108 2.3E-46 T 12-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE IM45_924 4c775c10a16b5d9c23e52bce56449854 108 SUPERFAMILY SSF69721 2 108 1.12E-38 T 12-10-2018 IPR025526 DsrC-like domain superfamily IM45_131 9ff00fc64dffe9dfb0540555226cac0f 504 Pfam PF01384 Phosphate transporter family 30 493 6.5E-88 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 IM45_127 32f36f480a85c2bf0bf706646230baa8 245 Pfam PF01914 MarC family integral membrane protein 34 241 7.4E-59 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 IM45_127 32f36f480a85c2bf0bf706646230baa8 245 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 39 238 1.9E-35 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 IM45_668 dac8993953bac7960437a2ee691d0a0d 208 SUPERFAMILY SSF89392 38 206 2.71E-40 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX IM45_668 dac8993953bac7960437a2ee691d0a0d 208 Pfam PF03550 Outer membrane lipoprotein LolB 54 205 1.4E-36 T 12-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 IM45_668 dac8993953bac7960437a2ee691d0a0d 208 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 8 207 21.943 T 12-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 IM45_668 dac8993953bac7960437a2ee691d0a0d 208 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 12 206 1.1E-52 T 12-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 IM45_668 dac8993953bac7960437a2ee691d0a0d 208 Gene3D G3DSA:2.50.20.10 33 207 6.3E-46 T 12-10-2018 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 Gene3D G3DSA:3.40.50.10490 450 597 1.6E-143 T 12-10-2018 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 SUPERFAMILY SSF56235 2 236 2.92E-70 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 612 1.1E-249 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 Gene3D G3DSA:3.60.20.10 2 241 4.4E-77 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 Pfam PF01380 SIS domain 292 420 1.1E-29 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 Pfam PF01380 SIS domain 466 594 1.5E-25 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 SUPERFAMILY SSF53697 248 612 7.68E-104 T 12-10-2018 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 Gene3D G3DSA:3.40.50.10490 252 611 1.6E-143 T 12-10-2018 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 Pfam PF13522 Glutamine amidotransferase domain 63 185 4.3E-20 T 12-10-2018 IM45_323 00e7aa67572fdc2b5a63d52904fefbbb 612 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 612 39.077 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 IM45_1064 bae067548100b31a8fd0a0b35eaa0da2 187 Pfam PF02622 Uncharacterized ACR, COG1678 12 174 2.9E-47 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 IM45_1064 bae067548100b31a8fd0a0b35eaa0da2 187 Gene3D G3DSA:3.40.1740.10 1 187 7.9E-63 T 12-10-2018 IM45_1064 bae067548100b31a8fd0a0b35eaa0da2 187 SUPERFAMILY SSF143456 1 187 1.83E-64 T 12-10-2018 IM45_1064 bae067548100b31a8fd0a0b35eaa0da2 187 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 1 187 38.551 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 IM45_001 8ee26e05d7419ddc5344b25caecfaeb9 512 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 19 507 1.6E-224 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 IM45_001 8ee26e05d7419ddc5344b25caecfaeb9 512 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 20 505 1.9E-194 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 IM45_001 8ee26e05d7419ddc5344b25caecfaeb9 512 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 16 507 49.129 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 IM45_001 8ee26e05d7419ddc5344b25caecfaeb9 512 SUPERFAMILY SSF51905 15 336 1.55E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PRINTS PR01806 Virulence factor MviN signature 33 52 2.5E-83 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PRINTS PR01806 Virulence factor MviN signature 357 376 2.5E-83 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PRINTS PR01806 Virulence factor MviN signature 409 426 2.5E-83 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PRINTS PR01806 Virulence factor MviN signature 259 285 2.5E-83 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PRINTS PR01806 Virulence factor MviN signature 157 178 2.5E-83 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PRINTS PR01806 Virulence factor MviN signature 52 68 2.5E-83 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PRINTS PR01806 Virulence factor MviN signature 133 157 2.5E-83 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 467 20.122 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 PIRSF PIRSF002869 1 508 1.2E-168 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 Pfam PF03023 MviN-like protein 28 478 5.2E-147 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_637 949746d9f9fe888663c4a3106a6f3252 510 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 502 7.1E-160 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ IM45_1077 9db83638260a2a74d2867f0c53d54ba8 151 Gene3D G3DSA:3.30.1490.190 90 149 1.9E-15 T 12-10-2018 IM45_1077 9db83638260a2a74d2867f0c53d54ba8 151 Pfam PF01475 Ferric uptake regulator family 20 138 5.9E-16 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 IM45_1077 9db83638260a2a74d2867f0c53d54ba8 151 SUPERFAMILY SSF46785 12 144 4.93E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_1077 9db83638260a2a74d2867f0c53d54ba8 151 Gene3D G3DSA:1.10.10.10 2 89 3.3E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 3.7E-19 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 370 2.7E-65 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 366 1.3E-132 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 Gene3D G3DSA:3.40.430.10 137 374 9.3E-68 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 Gene3D G3DSA:3.40.140.10 3 136 4.6E-40 T 12-10-2018 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 SUPERFAMILY SSF53927 4 146 1.63E-43 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 Pfam PF01872 RibD C-terminal domain 148 365 6.4E-51 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 SUPERFAMILY SSF53597 145 367 9.36E-53 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 IM45_1318 7b9463e9d8358156aaebbc30a3a92a12 375 PIRSF PIRSF006769 1 373 3.4E-120 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 SUPERFAMILY SSF55424 343 466 1.32E-38 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 SUPERFAMILY SSF51905 3 337 9.72E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 454 3.3E-33 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 328 2.9E-60 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.4E-40 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 2.4E-40 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 2.4E-40 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 2.4E-40 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 2.4E-40 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 3.0E-70 T 12-10-2018 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 Gene3D G3DSA:3.50.50.60 9 332 1.6E-110 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 Gene3D G3DSA:3.50.50.60 150 271 1.6E-110 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 PIRSF PIRSF000350 1 467 3.1E-85 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 7 460 9.1E-145 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 IM45_1117 7aff1659e9a9a57d3175cc649bc43676 472 Gene3D G3DSA:3.30.390.30 346 467 1.1E-41 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 IM45_876 b4217dfc051d44de62bde36e907bf37e 96 Gene3D G3DSA:2.40.240.10 1 94 6.7E-31 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_876 b4217dfc051d44de62bde36e907bf37e 96 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 93 7.0E-28 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 IM45_876 b4217dfc051d44de62bde36e907bf37e 96 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 2 94 25.29 T 12-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 IM45_876 b4217dfc051d44de62bde36e907bf37e 96 Pfam PF01386 Ribosomal L25p family 4 91 7.5E-21 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 IM45_876 b4217dfc051d44de62bde36e907bf37e 96 SUPERFAMILY SSF50715 1 94 7.67E-28 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 IM45_228 ba38d6d4d6dbd4e13e278fa6eb3befcf 227 TIGRFAM TIGR02796 tolQ: protein TolQ 5 219 1.8E-88 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 IM45_228 ba38d6d4d6dbd4e13e278fa6eb3befcf 227 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 4 224 40.445 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 IM45_228 ba38d6d4d6dbd4e13e278fa6eb3befcf 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 79 207 2.4E-41 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel IM45_654 f3186d45ab38c8d5fba4c244c9410fa9 148 Gene3D G3DSA:3.40.50.10110 1 145 1.6E-46 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily IM45_654 f3186d45ab38c8d5fba4c244c9410fa9 148 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 141 6.7E-35 T 12-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 IM45_654 f3186d45ab38c8d5fba4c244c9410fa9 148 SUPERFAMILY SSF102400 1 144 1.27E-41 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily IM45_1193 6294510906f3292206a57d409b6e9c9b 319 Gene3D G3DSA:3.90.226.10 4 319 1.9E-116 T 12-10-2018 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 SUPERFAMILY SSF52096 6 318 9.19E-103 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily IM45_1193 6294510906f3292206a57d409b6e9c9b 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 151 1.1E-61 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 5.9E-49 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 5.9E-49 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 5.9E-49 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 5.9E-49 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 5.9E-49 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 5.9E-49 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 49.764 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_1193 6294510906f3292206a57d409b6e9c9b 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 1.8E-161 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 IM45_920 0049ae195264ec415b3994f53de00187 527 SUPERFAMILY SSF54211 294 485 3.68E-33 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold IM45_920 0049ae195264ec415b3994f53de00187 527 Pfam PF13654 AAA domain 65 264 6.5E-21 T 12-10-2018 IM45_920 0049ae195264ec415b3994f53de00187 527 Gene3D G3DSA:3.30.230.10 271 508 5.6E-87 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup IM45_920 0049ae195264ec415b3994f53de00187 527 Gene3D G3DSA:3.40.50.300 47 170 3.6E-13 T 12-10-2018 IM45_920 0049ae195264ec415b3994f53de00187 527 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 437 455 6.0E-9 T 12-10-2018 IM45_920 0049ae195264ec415b3994f53de00187 527 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 407 426 6.0E-9 T 12-10-2018 IM45_920 0049ae195264ec415b3994f53de00187 527 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 377 396 6.0E-9 T 12-10-2018 IM45_920 0049ae195264ec415b3994f53de00187 527 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 294 310 6.0E-9 T 12-10-2018 IM45_920 0049ae195264ec415b3994f53de00187 527 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 380 484 1.7E-9 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 IM45_1338 468b85e52c8c2e4904684921d7244fe2 315 Pfam PF01513 ATP-NAD kinase 22 286 7.0E-70 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 IM45_1338 468b85e52c8c2e4904684921d7244fe2 315 Hamap MF_00361 NAD kinase [nadK]. 21 302 33.011 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 IM45_1338 468b85e52c8c2e4904684921d7244fe2 315 Gene3D G3DSA:2.60.200.30 143 279 1.2E-94 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 IM45_1338 468b85e52c8c2e4904684921d7244fe2 315 Gene3D G3DSA:3.40.50.10330 38 302 1.2E-94 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 IM45_1338 468b85e52c8c2e4904684921d7244fe2 315 SUPERFAMILY SSF111331 22 303 1.44E-92 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily IM45_432 474f4c43c07fb0822664cd2baad848e4 356 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 340 1.7E-150 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 IM45_432 474f4c43c07fb0822664cd2baad848e4 356 Gene3D G3DSA:3.90.25.10 202 334 5.8E-124 T 12-10-2018 IM45_432 474f4c43c07fb0822664cd2baad848e4 356 SUPERFAMILY SSF51735 1 339 8.53E-89 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily IM45_432 474f4c43c07fb0822664cd2baad848e4 356 Gene3D G3DSA:3.40.50.720 3 326 5.8E-124 T 12-10-2018 IM45_432 474f4c43c07fb0822664cd2baad848e4 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 326 1.2E-88 T 12-10-2018 IPR016040 NAD(P)-binding domain IM45_140 3416a0d13cd4ec53d68c6c28b53dd68b 320 PIRSF PIRSF003097 19 316 1.1E-84 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 IM45_140 3416a0d13cd4ec53d68c6c28b53dd68b 320 Pfam PF02687 FtsX-like permease family 222 311 8.7E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 IM45_057 a56e5b6f0dd83d156b59d30068696d40 355 Gene3D G3DSA:1.20.1090.10 173 353 1.1E-58 T 12-10-2018 IM45_057 a56e5b6f0dd83d156b59d30068696d40 355 Pfam PF01761 3-dehydroquinate synthase 67 325 9.3E-105 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 IM45_057 a56e5b6f0dd83d156b59d30068696d40 355 SUPERFAMILY SSF56796 4 341 2.49E-103 T 12-10-2018 IM45_057 a56e5b6f0dd83d156b59d30068696d40 355 Gene3D G3DSA:3.40.50.1970 1 172 2.7E-60 T 12-10-2018 IM45_057 a56e5b6f0dd83d156b59d30068696d40 355 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 347 1.5E-111 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 IM45_057 a56e5b6f0dd83d156b59d30068696d40 355 PIRSF PIRSF001455 8 355 5.7E-102 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 IM45_057 a56e5b6f0dd83d156b59d30068696d40 355 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 355 66.642 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 TIGRFAM TIGR00016 ackA: acetate kinase 1 399 5.2E-170 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 PRINTS PR00471 Acetate kinase family signature 380 392 3.7E-46 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 PRINTS PR00471 Acetate kinase family signature 6 17 3.7E-46 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 PRINTS PR00471 Acetate kinase family signature 206 227 3.7E-46 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 PRINTS PR00471 Acetate kinase family signature 176 189 3.7E-46 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 PRINTS PR00471 Acetate kinase family signature 325 341 3.7E-46 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 PRINTS PR00471 Acetate kinase family signature 302 315 3.7E-46 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 PIRSF PIRSF000722 2 400 2.3E-140 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 206 223 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 SUPERFAMILY SSF53067 161 398 2.78E-80 T 12-10-2018 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 Pfam PF00871 Acetokinase family 6 393 3.6E-161 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 Hamap MF_00020 Acetate kinase [ackA]. 1 400 174.337 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 SUPERFAMILY SSF53067 4 199 3.8E-59 T 12-10-2018 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 Gene3D G3DSA:3.30.420.40 3 198 9.2E-73 T 12-10-2018 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 IM45_859 8f45033cf61d6a28b523a2adf7388cdb 400 Gene3D G3DSA:3.30.420.40 199 400 3.0E-80 T 12-10-2018 IM45_662 4bca88160c57bf7a4d3f5787ca7e7203 274 SUPERFAMILY SSF52402 4 273 5.42E-80 T 12-10-2018 IM45_662 4bca88160c57bf7a4d3f5787ca7e7203 274 TIGRFAM TIGR00552 nadE: NAD+ synthetase 27 273 5.9E-74 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 IM45_662 4bca88160c57bf7a4d3f5787ca7e7203 274 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 268 45.815 T 12-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 IM45_662 4bca88160c57bf7a4d3f5787ca7e7203 274 Gene3D G3DSA:3.40.50.620 1 274 1.7E-77 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_662 4bca88160c57bf7a4d3f5787ca7e7203 274 Pfam PF02540 NAD synthase 24 265 6.2E-71 T 12-10-2018 IPR022310 NAD/GMP synthase IM45_562 ff094701088a71d05b1c9b90098d013b 257 Pfam PF08241 Methyltransferase domain 53 144 5.6E-22 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 IM45_562 ff094701088a71d05b1c9b90098d013b 257 Gene3D G3DSA:3.40.50.150 17 206 9.3E-34 T 12-10-2018 IM45_562 ff094701088a71d05b1c9b90098d013b 257 SUPERFAMILY SSF53335 16 249 1.1E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase IM45_562 ff094701088a71d05b1c9b90098d013b 257 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 10 256 28.035 T 12-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 IM45_562 ff094701088a71d05b1c9b90098d013b 257 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 18 255 3.5E-64 T 12-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 SMART SM00729 43 255 1.1E-32 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 TIGRFAM TIGR00433 bioB: biotin synthase 15 310 3.0E-120 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 220 310 6.6E-19 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 SUPERFAMILY SSF102114 6 311 5.23E-86 T 12-10-2018 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 PIRSF PIRSF001619 1 318 1.3E-132 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 SMART SM00876 220 312 1.7E-44 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 Gene3D G3DSA:3.20.20.70 4 314 1.9E-125 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 Hamap MF_01694 Biotin synthase [bioB]. 5 313 41.1 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 IM45_560 12489b8a440f9fa75e241b8f0471a279 334 Pfam PF04055 Radical SAM superfamily 50 195 4.9E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 13 617 3.6E-173 T 12-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 SUPERFAMILY SSF52540 290 617 1.68E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 Gene3D G3DSA:1.10.10.1020 1 116 2.8E-29 T 12-10-2018 IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 14 616 49.782 T 12-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 Pfam PF13538 UvrD-like helicase C-terminal domain 546 592 1.6E-15 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 Gene3D G3DSA:3.40.50.300 117 368 4.1E-73 T 12-10-2018 IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 SMART SM00382 171 328 8.8E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 Pfam PF13604 AAA domain 172 327 2.9E-30 T 12-10-2018 IM45_1209 15fc5d89ec7dcda938d6fa70c92c4b0b 627 SUPERFAMILY SSF52540 7 373 7.59E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase IM45_193 9b0f9a250dbe165cf3a67f19e65028c0 111 Pfam PF00893 Small Multidrug Resistance protein 1 93 9.5E-27 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 IM45_193 9b0f9a250dbe165cf3a67f19e65028c0 111 SUPERFAMILY SSF103481 4 104 3.4E-18 T 12-10-2018 IM45_193 9b0f9a250dbe165cf3a67f19e65028c0 111 Gene3D G3DSA:1.10.3730.20 1 109 1.9E-35 T 12-10-2018 IM45_1330 08fd3bb986fcd90abdfbdfd1d2c91f52 1020 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 677 1020 4.4E-58 T 12-10-2018 IPR007452 Translocation and assembly module TamB IM45_882 49a66e040173aedd40bd7c19b1951f68 486 Gene3D G3DSA:1.20.1740.10 14 477 4.1E-56 T 12-10-2018 IM45_882 49a66e040173aedd40bd7c19b1951f68 486 ProSitePatterns PS00218 Amino acid permeases signature. 47 78 - T 12-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 IM45_882 49a66e040173aedd40bd7c19b1951f68 486 Pfam PF00324 Amino acid permease 22 472 4.0E-131 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 IM45_882 49a66e040173aedd40bd7c19b1951f68 486 PIRSF PIRSF006060 1 481 1.4E-73 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 IM45_988 20a31fdecc2a3476a66c5aa587d2bfa6 176 SUPERFAMILY SSF158442 15 160 1.12E-39 T 12-10-2018 IPR023380 DsbB-like superfamily IM45_988 20a31fdecc2a3476a66c5aa587d2bfa6 176 Pfam PF02600 Disulfide bond formation protein DsbB 12 159 3.1E-38 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 IM45_988 20a31fdecc2a3476a66c5aa587d2bfa6 176 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 7 167 19.521 T 12-10-2018 IPR022920 Disulphide bond formation protein DsbB IM45_988 20a31fdecc2a3476a66c5aa587d2bfa6 176 Gene3D G3DSA:1.20.1550.10 1 175 4.1E-53 T 12-10-2018 IPR023380 DsbB-like superfamily IM45_609 bc56ecb67212735d2aa005f8564c0937 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 12-10-2018 IPR033135 ClpP, histidine active site IM45_609 bc56ecb67212735d2aa005f8564c0937 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 2.4E-104 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 IM45_609 bc56ecb67212735d2aa005f8564c0937 194 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.9E-52 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 IM45_609 bc56ecb67212735d2aa005f8564c0937 194 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.9E-52 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 IM45_609 bc56ecb67212735d2aa005f8564c0937 194 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.9E-52 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 IM45_609 bc56ecb67212735d2aa005f8564c0937 194 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.9E-52 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 IM45_609 bc56ecb67212735d2aa005f8564c0937 194 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.9E-52 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 IM45_609 bc56ecb67212735d2aa005f8564c0937 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 43.02 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 IM45_609 bc56ecb67212735d2aa005f8564c0937 194 SUPERFAMILY SSF52096 13 191 9.23E-71 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily IM45_609 bc56ecb67212735d2aa005f8564c0937 194 Pfam PF00574 Clp protease 13 192 9.8E-86 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA IM45_609 bc56ecb67212735d2aa005f8564c0937 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 12-10-2018 IPR018215 ClpP, Ser active site IM45_609 bc56ecb67212735d2aa005f8564c0937 194 Gene3D G3DSA:3.90.226.10 1 194 1.3E-79 T 12-10-2018 IM45_1197 7edc834b71b74a15ebf727536eb88a5a 231 SUPERFAMILY SSF52980 11 229 1.39E-72 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 IM45_1197 7edc834b71b74a15ebf727536eb88a5a 231 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 14 228 2.6E-98 T 12-10-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 IM45_1197 7edc834b71b74a15ebf727536eb88a5a 231 Gene3D G3DSA:3.40.600.10 8 231 3.8E-49 T 12-10-2018 IPR037057 DNA mismatch repair MutH/Restriction endonuclease, type II superfamily GO:0003677|GO:0004519 IM45_1197 7edc834b71b74a15ebf727536eb88a5a 231 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 231 139.14 T 12-10-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 IM45_1197 7edc834b71b74a15ebf727536eb88a5a 231 Pfam PF02976 DNA mismatch repair enzyme MutH 62 160 1.1E-30 T 12-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 IM45_1197 7edc834b71b74a15ebf727536eb88a5a 231 SMART SM00927 62 160 5.0E-60 T 12-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 IM45_427 f5f4bac6bb549931b173ca42e5d625ef 414 Pfam PF01943 Polysaccharide biosynthesis protein 5 281 1.4E-8 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 IM45_1000 0c43a6dac4c4770f3495471f3ac31c0f 268 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 1 266 8.4E-111 T 12-10-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 IM45_1000 0c43a6dac4c4770f3495471f3ac31c0f 268 Pfam PF03609 PTS system sorbose-specific iic component 6 237 5.3E-73 T 12-10-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 IM45_1081 8bd749d27fa86922bd5ef484463702e7 119 Gene3D G3DSA:3.40.1260.10 1 119 6.9E-35 T 12-10-2018 IPR027396 DsrEFH-like IM45_1081 8bd749d27fa86922bd5ef484463702e7 119 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 4 119 2.0E-40 T 12-10-2018 IPR017462 Sulphur relay, TusC/DsrF IM45_1081 8bd749d27fa86922bd5ef484463702e7 119 Pfam PF02635 DsrE/DsrF-like family 2 119 9.8E-20 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein IM45_1081 8bd749d27fa86922bd5ef484463702e7 119 SUPERFAMILY SSF75169 1 119 2.52E-32 T 12-10-2018 IPR027396 DsrEFH-like IM45_1237 fbce1d309e704a9faf107a2bf5586c1a 274 SUPERFAMILY SSF56300 1 262 2.43E-59 T 12-10-2018 IM45_1237 fbce1d309e704a9faf107a2bf5586c1a 274 Pfam PF00149 Calcineurin-like phosphoesterase 2 134 2.4E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 IM45_1237 fbce1d309e704a9faf107a2bf5586c1a 274 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 271 49.744 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 IM45_1237 fbce1d309e704a9faf107a2bf5586c1a 274 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 265 1.4E-136 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 IM45_1237 fbce1d309e704a9faf107a2bf5586c1a 274 Gene3D G3DSA:3.60.21.10 1 273 1.5E-79 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like IM45_1237 fbce1d309e704a9faf107a2bf5586c1a 274 PIRSF PIRSF000903 1 274 8.5E-121 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 Gene3D G3DSA:2.40.50.140 1 124 3.6E-61 T 12-10-2018 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 PIRSF PIRSF002133 1 124 4.1E-54 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 37.285 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 Pfam PF00164 Ribosomal protein S12/S23 13 123 2.6E-41 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 SUPERFAMILY SSF50249 3 123 2.14E-51 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold IM45_1085 a558c57e97cbbea24f45c3d4cf78ee6e 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 5.0E-68 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1004 af3c4472ae37de88fe9f15cc7ed2b867 503 SUPERFAMILY SSF54631 270 402 2.53E-19 T 12-10-2018 IM45_1004 af3c4472ae37de88fe9f15cc7ed2b867 503 Gene3D G3DSA:3.10.580.10 263 415 5.7E-34 T 12-10-2018 IM45_1004 af3c4472ae37de88fe9f15cc7ed2b867 503 Pfam PF03741 Integral membrane protein TerC family 1 186 4.3E-41 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 IM45_1004 af3c4472ae37de88fe9f15cc7ed2b867 503 Pfam PF03471 Transporter associated domain 416 495 5.2E-13 T 12-10-2018 IPR005170 Transporter-associated domain IM45_1004 af3c4472ae37de88fe9f15cc7ed2b867 503 SUPERFAMILY SSF56176 410 494 1.33E-14 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 IM45_1004 af3c4472ae37de88fe9f15cc7ed2b867 503 SMART SM01091 415 496 8.4E-13 T 12-10-2018 IPR005170 Transporter-associated domain IM45_1004 af3c4472ae37de88fe9f15cc7ed2b867 503 Gene3D G3DSA:3.30.465.10 416 496 1.9E-13 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 IM45_101 6bbc5dff99caf9b6585ce97878f643ce 617 Pfam PF13667 ThiC-associated domain 30 111 8.7E-33 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 IM45_101 6bbc5dff99caf9b6585ce97878f643ce 617 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 150 601 5.2E-218 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 IM45_101 6bbc5dff99caf9b6585ce97878f643ce 617 Pfam PF01964 Radical SAM ThiC family 151 598 4.0E-197 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 IM45_101 6bbc5dff99caf9b6585ce97878f643ce 617 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 150 603 98.202 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 IM45_101 6bbc5dff99caf9b6585ce97878f643ce 617 Gene3D G3DSA:3.20.20.540 221 534 1.4E-150 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 IM45_1363 d769cce7e874d62b7d92dd2b62a3b0a8 213 Gene3D G3DSA:3.90.870.10 1 212 3.4E-87 T 12-10-2018 IM45_1363 d769cce7e874d62b7d92dd2b62a3b0a8 213 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 19 208 8.4E-79 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1363 d769cce7e874d62b7d92dd2b62a3b0a8 213 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 11 213 41.229 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1363 d769cce7e874d62b7d92dd2b62a3b0a8 213 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 209 1.7E-77 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 IM45_1363 d769cce7e874d62b7d92dd2b62a3b0a8 213 SUPERFAMILY SSF55821 7 210 6.18E-82 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily IM45_591 456101bf5cef6e3897b87adfe1ea2231 209 SUPERFAMILY SSF52833 22 204 8.93E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily IM45_591 456101bf5cef6e3897b87adfe1ea2231 209 Gene3D G3DSA:3.40.30.10 19 208 1.7E-47 T 12-10-2018 IM45_591 456101bf5cef6e3897b87adfe1ea2231 209 PIRSF PIRSF001488 1 208 4.0E-75 T 12-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL IM45_591 456101bf5cef6e3897b87adfe1ea2231 209 Pfam PF01323 DSBA-like thioredoxin domain 41 186 3.6E-24 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 IM45_431 f524d4819c1538feaa641a78f8641401 373 PIRSF PIRSF000390 1 373 1.4E-110 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase IM45_431 f524d4819c1538feaa641a78f8641401 373 SUPERFAMILY SSF53383 2 371 7.54E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase IM45_431 f524d4819c1538feaa641a78f8641401 373 Gene3D G3DSA:3.90.1150.10 250 372 4.9E-25 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 IM45_431 f524d4819c1538feaa641a78f8641401 373 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 368 1.6E-84 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase IM45_431 f524d4819c1538feaa641a78f8641401 373 Gene3D G3DSA:3.40.640.10 1 249 4.0E-82 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 IM45_431 f524d4819c1538feaa641a78f8641401 373 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 1 371 9.8E-197 T 12-10-2018 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 IM45_593 1d05ace1bdc4d2ccb0d5db077e3e7e6d 64 Pfam PF15930 Domain of unknown function 8 49 1.3E-9 T 12-10-2018 IPR031830 Uncharacterised protein YdiH IM45_613 9de6650527f36892069efae7a7025750 106 SUPERFAMILY SSF82657 1 86 1.7E-25 T 12-10-2018 IPR036065 BolA-like superfamily IM45_613 9de6650527f36892069efae7a7025750 106 Gene3D G3DSA:3.30.300.90 1 88 1.9E-24 T 12-10-2018 IM45_613 9de6650527f36892069efae7a7025750 106 Pfam PF01722 BolA-like protein 11 82 2.4E-21 T 12-10-2018 IPR002634 BolA protein IM45_613 9de6650527f36892069efae7a7025750 106 PIRSF PIRSF003113 1 98 3.2E-26 T 12-10-2018 IPR002634 BolA protein IM45_113 b9399fbba9213229fd80638dad2948f1 160 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 9 154 2.2E-34 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 IM45_113 b9399fbba9213229fd80638dad2948f1 160 PIRSF PIRSF018472 1 160 4.7E-53 T 12-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type IM45_113 b9399fbba9213229fd80638dad2948f1 160 Pfam PF04093 rod shape-determining protein MreD 8 154 6.4E-32 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 IM45_639 b1e5d283ed90eb1b70ee840dc9554701 127 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 126 1.2E-32 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 IM45_639 b1e5d283ed90eb1b70ee840dc9554701 127 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 25.071 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 IM45_639 b1e5d283ed90eb1b70ee840dc9554701 127 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 121 3.0E-22 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 IM45_639 b1e5d283ed90eb1b70ee840dc9554701 127 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 92 2.0E-29 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 IM45_639 b1e5d283ed90eb1b70ee840dc9554701 127 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 126 1.2E-46 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 IM45_639 b1e5d283ed90eb1b70ee840dc9554701 127 Gene3D G3DSA:3.90.470.20 1 127 1.3E-37 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 IM45_639 b1e5d283ed90eb1b70ee840dc9554701 127 SUPERFAMILY SSF56214 3 125 5.62E-30 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 IM45_893 9e8d7a6f5c7e80b305e10a143da615e1 258 SUPERFAMILY SSF51366 1 257 7.38E-69 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 IM45_893 9e8d7a6f5c7e80b305e10a143da615e1 258 Pfam PF00977 Histidine biosynthesis protein 5 239 9.5E-74 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 IM45_893 9e8d7a6f5c7e80b305e10a143da615e1 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 2.3E-109 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 IM45_893 9e8d7a6f5c7e80b305e10a143da615e1 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 42.39 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 IM45_893 9e8d7a6f5c7e80b305e10a143da615e1 258 Gene3D G3DSA:3.20.20.70 1 258 1.0E-86 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_1425 1a1b3ab64220fe50db0a9d5632dbe5ca 267 SUPERFAMILY SSF53613 3 267 6.24E-76 T 12-10-2018 IPR029056 Ribokinase-like IM45_1425 1a1b3ab64220fe50db0a9d5632dbe5ca 267 Gene3D G3DSA:3.40.1190.20 3 267 3.3E-95 T 12-10-2018 IPR029056 Ribokinase-like IM45_1425 1a1b3ab64220fe50db0a9d5632dbe5ca 267 Pfam PF08543 Phosphomethylpyrimidine kinase 14 261 8.1E-89 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 IM45_1425 1a1b3ab64220fe50db0a9d5632dbe5ca 267 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 263 2.7E-97 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 IM45_1129 983a66f4cefab6aa9044dd64dd5e36e2 180 Pfam PF05258 Protein of unknown function (DUF721) 27 98 4.1E-10 T 12-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 IM45_434 4f6e9957f6492c5ecf4f3d61eb20b577 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 370 1.3E-120 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 IM45_434 4f6e9957f6492c5ecf4f3d61eb20b577 377 Gene3D G3DSA:3.40.50.2000 2 367 3.3E-146 T 12-10-2018 IM45_434 4f6e9957f6492c5ecf4f3d61eb20b577 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 371 3.9E-156 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 IM45_434 4f6e9957f6492c5ecf4f3d61eb20b577 377 Gene3D G3DSA:3.40.50.2000 187 356 3.3E-146 T 12-10-2018 IM45_434 4f6e9957f6492c5ecf4f3d61eb20b577 377 SUPERFAMILY SSF53756 2 372 2.44E-133 T 12-10-2018 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 250 1.3E-103 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 Hamap MF_01974 Methionine aminopeptidase [map]. 3 251 41.874 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 168 186 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 SUPERFAMILY SSF55920 4 253 1.06E-83 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 Gene3D G3DSA:3.90.230.10 2 264 1.2E-108 T 12-10-2018 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 9.0E-23 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 162 174 9.0E-23 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 9.0E-23 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 92 108 9.0E-23 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 IM45_1161 b5eca4025f39fbac268cf5e9413015b9 264 Pfam PF00557 Metallopeptidase family M24 13 240 1.8E-49 T 12-10-2018 IPR000994 Peptidase M24 IM45_752 ecef12a8ac370259ec2a86dfd04f9077 100 SUPERFAMILY SSF54189 7 97 2.12E-26 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_752 ecef12a8ac370259ec2a86dfd04f9077 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 12-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_752 ecef12a8ac370259ec2a86dfd04f9077 100 Gene3D G3DSA:3.30.70.330 1 99 2.1E-31 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily IM45_752 ecef12a8ac370259ec2a86dfd04f9077 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 19.82 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 IM45_752 ecef12a8ac370259ec2a86dfd04f9077 100 Pfam PF00276 Ribosomal protein L23 10 94 6.3E-26 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 IM45_1225 df0ee0b155470053b41f4bbe5d3379c1 171 TIGRFAM TIGR00077 lspA: signal peptidase II 7 165 7.7E-47 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 IM45_1225 df0ee0b155470053b41f4bbe5d3379c1 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 141 157 1.9E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 IM45_1225 df0ee0b155470053b41f4bbe5d3379c1 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 57 65 1.9E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 IM45_1225 df0ee0b155470053b41f4bbe5d3379c1 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 105 120 1.9E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 IM45_1225 df0ee0b155470053b41f4bbe5d3379c1 171 ProSitePatterns PS00855 Signal peptidases II signature. 108 120 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 IM45_1225 df0ee0b155470053b41f4bbe5d3379c1 171 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 11 166 16.464 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 IM45_1225 df0ee0b155470053b41f4bbe5d3379c1 171 Pfam PF01252 Signal peptidase (SPase) II 20 161 3.4E-34 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 IM45_1407 c2d4cb723c21130d2050905086faa1b2 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 5.9E-40 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1407 c2d4cb723c21130d2050905086faa1b2 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 25.143 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1407 c2d4cb723c21130d2050905086faa1b2 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 5.2E-36 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1407 c2d4cb723c21130d2050905086faa1b2 103 SUPERFAMILY SSF141091 1 101 2.49E-35 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_1407 c2d4cb723c21130d2050905086faa1b2 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_501 f8c8a86dc93b235c560bd443480925d0 245 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 21 242 8.3E-88 T 12-10-2018 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8 IM45_501 f8c8a86dc93b235c560bd443480925d0 245 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 9 243 37.832 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 IM45_501 f8c8a86dc93b235c560bd443480925d0 245 SUPERFAMILY SSF52402 22 208 8.37E-47 T 12-10-2018 IM45_501 f8c8a86dc93b235c560bd443480925d0 245 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 33 243 1.2E-80 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 IM45_501 f8c8a86dc93b235c560bd443480925d0 245 PIRSF PIRSF000857 2 245 2.1E-51 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 IM45_501 f8c8a86dc93b235c560bd443480925d0 245 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 49 219 7.7E-45 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 IM45_501 f8c8a86dc93b235c560bd443480925d0 245 Gene3D G3DSA:3.40.50.620 2 216 3.1E-58 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold IM45_469 015d7ef486e41c0e46f9b14be2641ab1 523 Gene3D G3DSA:3.30.590.20 19 522 1.6E-179 T 12-10-2018 IM45_469 015d7ef486e41c0e46f9b14be2641ab1 523 SUPERFAMILY SSF55931 9 515 1.05E-192 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 IM45_469 015d7ef486e41c0e46f9b14be2641ab1 523 Pfam PF04262 Glutamate-cysteine ligase 12 381 2.5E-166 T 12-10-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 IM45_469 015d7ef486e41c0e46f9b14be2641ab1 523 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 7 517 1.0E-227 T 12-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 IM45_469 015d7ef486e41c0e46f9b14be2641ab1 523 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 523 204.318 T 12-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 IM45_640 0eaf21d78e577755e31f5fbbb8eeb30e 249 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 12 241 1.2E-102 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 IM45_640 0eaf21d78e577755e31f5fbbb8eeb30e 249 Gene3D G3DSA:3.20.20.70 4 249 2.4E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 IM45_640 0eaf21d78e577755e31f5fbbb8eeb30e 249 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 12 244 1.0E-102 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 IM45_640 0eaf21d78e577755e31f5fbbb8eeb30e 249 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 249 121.718 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 IM45_640 0eaf21d78e577755e31f5fbbb8eeb30e 249 SUPERFAMILY SSF63892 10 246 3.92E-99 T 12-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 IM45_833 6b3addfea2388ea019883b663115f187 486 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 2 473 17.077 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 IM45_833 6b3addfea2388ea019883b663115f187 486 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 6 473 4.1E-129 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 IM45_833 6b3addfea2388ea019883b663115f187 486 Pfam PF00361 Proton-conducting membrane transporter 121 417 3.7E-75 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_1053 f3e13e529c1b24ade4ad3f3dba5f07d1 298 Gene3D G3DSA:3.60.10.10 65 287 8.4E-16 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily IM45_1053 f3e13e529c1b24ade4ad3f3dba5f07d1 298 SUPERFAMILY SSF56219 67 282 8.24E-24 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily IM45_791 b078c29388a3375209450a7c32bfc4fa 38 SUPERFAMILY SSF57840 1 38 2.22E-17 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_791 b078c29388a3375209450a7c32bfc4fa 38 Pfam PF00444 Ribosomal protein L36 1 38 5.3E-20 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_791 b078c29388a3375209450a7c32bfc4fa 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 1.0E-7 T 12-10-2018 IM45_791 b078c29388a3375209450a7c32bfc4fa 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 3.1E-22 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_791 b078c29388a3375209450a7c32bfc4fa 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_791 b078c29388a3375209450a7c32bfc4fa 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.484 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 IM45_383 e700cd80b7cd141ee40a46449f686197 331 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 145 153 - T 12-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 IM45_383 e700cd80b7cd141ee40a46449f686197 331 Gene3D G3DSA:3.40.190.10 28 297 9.9E-132 T 12-10-2018 IM45_383 e700cd80b7cd141ee40a46449f686197 331 Gene3D G3DSA:3.40.190.10 114 327 9.9E-132 T 12-10-2018 IM45_383 e700cd80b7cd141ee40a46449f686197 331 SUPERFAMILY SSF53850 21 329 2.72E-87 T 12-10-2018 IM45_383 e700cd80b7cd141ee40a46449f686197 331 Pfam PF13531 Bacterial extracellular solute-binding protein 32 282 3.7E-47 T 12-10-2018 IM45_383 e700cd80b7cd141ee40a46449f686197 331 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 13 328 7.7E-160 T 12-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 IM45_690 8ba425e07846762daae31eb469dd8103 197 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 1 196 46.549 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 IM45_690 8ba425e07846762daae31eb469dd8103 197 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 5 194 8.5E-89 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 IM45_690 8ba425e07846762daae31eb469dd8103 197 Gene3D G3DSA:3.40.50.10990 1 174 1.1E-73 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 IM45_690 8ba425e07846762daae31eb469dd8103 197 SUPERFAMILY SSF142695 3 173 4.84E-64 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 IM45_690 8ba425e07846762daae31eb469dd8103 197 Pfam PF00925 GTP cyclohydrolase II 5 170 1.1E-65 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 IM45_696 dc083590da86463742b90d5e9625cb0d 253 Hamap MF_01067 UPF0259 membrane protein YciC [yciC]. 1 251 18.62 T 12-10-2018 IPR009627 Uncharacterised protein family UPF0259 IM45_696 dc083590da86463742b90d5e9625cb0d 253 Pfam PF06790 Uncharacterised protein family (UPF0259) 1 249 3.9E-71 T 12-10-2018 IPR009627 Uncharacterised protein family UPF0259 IM45_931 6f71b4ce44dc1a9217eadbc20baebb58 186 SUPERFAMILY SSF55821 4 183 1.37E-47 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily IM45_931 6f71b4ce44dc1a9217eadbc20baebb58 186 Pfam PF01300 Telomere recombination 10 186 5.4E-35 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 IM45_931 6f71b4ce44dc1a9217eadbc20baebb58 186 Gene3D G3DSA:3.90.870.10 2 184 3.0E-54 T 12-10-2018 IM45_931 6f71b4ce44dc1a9217eadbc20baebb58 186 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 1 184 37.185 T 12-10-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 IM45_1183 ab718f323c103adfdd93f635d293c5f4 166 PIRSF PIRSF002094 1 166 1.9E-54 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 IM45_1183 ab718f323c103adfdd93f635d293c5f4 166 Pfam PF03938 Outer membrane protein (OmpH-like) 12 164 2.2E-31 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 IM45_1183 ab718f323c103adfdd93f635d293c5f4 166 SMART SM00935 13 166 2.8E-46 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 IM45_1183 ab718f323c103adfdd93f635d293c5f4 166 Gene3D G3DSA:3.30.910.20 22 165 2.9E-45 T 12-10-2018 IPR024930 Skp domain superfamily IM45_1183 ab718f323c103adfdd93f635d293c5f4 166 SUPERFAMILY SSF111384 23 165 1.07E-32 T 12-10-2018 IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 SUPERFAMILY SSF52833 3 78 7.67E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 PRINTS PR00160 Glutaredoxin signature 4 22 9.4E-17 T 12-10-2018 IPR014025 Glutaredoxin subgroup IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 PRINTS PR00160 Glutaredoxin signature 46 59 9.4E-17 T 12-10-2018 IPR014025 Glutaredoxin subgroup IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 PRINTS PR00160 Glutaredoxin signature 60 73 9.4E-17 T 12-10-2018 IPR014025 Glutaredoxin subgroup IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 12-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 Pfam PF00462 Glutaredoxin 4 63 3.9E-22 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 79 1.0E-30 T 12-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 IM45_391 590ed1c78394fc7c4e23fdf0f8e2b244 79 Gene3D G3DSA:3.40.30.10 1 79 4.5E-24 T 12-10-2018 IM45_409 104768ab080a33491f1738af70ec6e82 320 Pfam PF08340 Domain of unknown function (DUF1732) 236 320 1.1E-32 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 IM45_409 104768ab080a33491f1738af70ec6e82 320 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 34 320 2.0E-111 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 IM45_409 104768ab080a33491f1738af70ec6e82 320 Pfam PF03755 YicC-like family, N-terminal region 35 186 9.1E-37 T 12-10-2018 IPR013527 YicC-like, N-terminal IM45_1316 77338e492b6976840282fec49634bf98 138 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 137 5.9E-62 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 IM45_1316 77338e492b6976840282fec49634bf98 138 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 138 72.791 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 IM45_1316 77338e492b6976840282fec49634bf98 138 Pfam PF03477 ATP cone domain 50 136 8.7E-15 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 IM45_068 b2098c36b5e13c794aef000922894c05 190 Pfam PF04972 BON domain 46 112 1.6E-10 T 12-10-2018 IPR007055 BON domain IM45_068 b2098c36b5e13c794aef000922894c05 190 Pfam PF04972 BON domain 125 184 1.3E-10 T 12-10-2018 IPR007055 BON domain IM45_068 b2098c36b5e13c794aef000922894c05 190 SMART SM00749 51 114 1.0E-6 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria IM45_068 b2098c36b5e13c794aef000922894c05 190 SMART SM00749 129 190 1.2 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria IM45_773 a928239bb3d602a6d746581bde71f8a4 179 Gene3D G3DSA:3.30.1440.10 1 179 9.6E-79 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_773 a928239bb3d602a6d746581bde71f8a4 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_773 a928239bb3d602a6d746581bde71f8a4 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.0E-39 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_773 a928239bb3d602a6d746581bde71f8a4 179 PIRSF PIRSF002161 1 179 1.7E-67 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_773 a928239bb3d602a6d746581bde71f8a4 179 Pfam PF00281 Ribosomal protein L5 25 80 8.9E-28 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_773 a928239bb3d602a6d746581bde71f8a4 179 SUPERFAMILY SSF55282 4 179 1.44E-75 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_773 a928239bb3d602a6d746581bde71f8a4 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.026 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 IM45_823 9ee11e54e08eb48782a1d75eb8c8de1c 176 SUPERFAMILY SSF110997 90 165 1.83E-13 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 IM45_823 9ee11e54e08eb48782a1d75eb8c8de1c 176 Gene3D G3DSA:3.30.70.1070 88 162 1.1E-6 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 IM45_823 9ee11e54e08eb48782a1d75eb8c8de1c 176 Pfam PF05036 Sporulation related domain 91 163 1.1E-11 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 IM45_743 48067e14df396c61f4d458bf2281b693 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 215 2.9E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 IM45_743 48067e14df396c61f4d458bf2281b693 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 5 110 1.1E-11 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 IM45_743 48067e14df396c61f4d458bf2281b693 224 Gene3D G3DSA:1.10.3720.10 1 217 5.0E-34 T 12-10-2018 IPR035906 MetI-like superfamily IM45_743 48067e14df396c61f4d458bf2281b693 224 SUPERFAMILY SSF161098 6 201 2.62E-25 T 12-10-2018 IPR035906 MetI-like superfamily IM45_841 7dc18225eeed0cf3520c391ecb32579b 176 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 17 158 6.1E-31 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_841 7dc18225eeed0cf3520c391ecb32579b 176 Gene3D G3DSA:1.20.120.1200 1 160 9.0E-41 T 12-10-2018 IM45_1055 1860d676c82372a72b761575db43d811 363 Gene3D G3DSA:1.10.530.10 184 359 5.8E-46 T 12-10-2018 IM45_1055 1860d676c82372a72b761575db43d811 363 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 218 246 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 IM45_1055 1860d676c82372a72b761575db43d811 363 Pfam PF11873 Domain of unknown function (DUF3393) 6 196 7.9E-61 T 12-10-2018 IPR024570 Murein transglycosylase-C, N-terminal IM45_1055 1860d676c82372a72b761575db43d811 363 SUPERFAMILY SSF53955 196 361 6.48E-34 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily IM45_1055 1860d676c82372a72b761575db43d811 363 Pfam PF01464 Transglycosylase SLT domain 201 321 2.5E-30 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 IM45_027 dd4dda9214d02a33d1b27e28b0e2a91c 76 Pfam PF09012 FeoC like transcriptional regulator 4 64 2.8E-7 T 12-10-2018 IPR015102 Transcriptional regulator HTH-type, FeoC IM45_027 dd4dda9214d02a33d1b27e28b0e2a91c 76 Gene3D G3DSA:1.10.10.10 1 73 3.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily IM45_027 dd4dda9214d02a33d1b27e28b0e2a91c 76 SUPERFAMILY SSF46785 1 68 1.05E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily IM45_769 7671542a6d694a282a41936767571fe4 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 7.8E-58 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 IM45_769 7671542a6d694a282a41936767571fe4 123 SMART SM01374 1 123 8.2E-83 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 IM45_769 7671542a6d694a282a41936767571fe4 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 IM45_769 7671542a6d694a282a41936767571fe4 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 27.245 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 IM45_769 7671542a6d694a282a41936767571fe4 123 SUPERFAMILY SSF50193 2 122 1.06E-49 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_769 7671542a6d694a282a41936767571fe4 123 Gene3D G3DSA:2.40.150.20 1 123 4.3E-55 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 IM45_769 7671542a6d694a282a41936767571fe4 123 Pfam PF00238 Ribosomal protein L14p/L23e 1 123 3.4E-53 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 IM45_844 f37c1a332f87f778a1cca811810cf8d4 333 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 211 224 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_844 f37c1a332f87f778a1cca811810cf8d4 333 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 323 23.605 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_844 f37c1a332f87f778a1cca811810cf8d4 333 Pfam PF00146 NADH dehydrogenase 17 317 6.4E-116 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 IM45_487 2b068efd860593d1b496e1e2b9e44c02 155 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 154 5.8E-67 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 IM45_487 2b068efd860593d1b496e1e2b9e44c02 155 Gene3D G3DSA:3.30.1330.50 1 155 2.7E-67 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 IM45_487 2b068efd860593d1b496e1e2b9e44c02 155 SUPERFAMILY SSF69765 1 154 4.84E-63 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 IM45_487 2b068efd860593d1b496e1e2b9e44c02 155 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 154 33.198 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 IM45_487 2b068efd860593d1b496e1e2b9e44c02 155 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 IM45_487 2b068efd860593d1b496e1e2b9e44c02 155 Pfam PF02542 YgbB family 1 154 2.0E-63 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 IM45_620 3b585d3eec227aa64656ea39476ed470 164 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 75 148 1.0E-12 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 IM45_620 3b585d3eec227aa64656ea39476ed470 164 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 69 163 5.4E-31 T 12-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 IM45_086 ee16f01518715bdbf902be7f24f0007d 74 Pfam PF03968 OstA-like protein 1 71 3.2E-6 T 12-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal IM45_086 ee16f01518715bdbf902be7f24f0007d 74 Gene3D G3DSA:2.60.450.10 1 74 1.1E-10 T 12-10-2018 IM45_827 0fe093c6f554b26e842cafd1e38d4504 159 Pfam PF02674 Colicin V production protein 4 141 2.8E-36 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 IM45_1229 5c9859ed63454b023bc2d288c7b9fce8 320 Gene3D G3DSA:3.40.1010.20 6 282 3.3E-107 T 12-10-2018 IM45_1229 5c9859ed63454b023bc2d288c7b9fce8 320 Pfam PF02401 LytB protein 3 282 6.8E-89 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 IM45_1229 5c9859ed63454b023bc2d288c7b9fce8 320 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 286 36.874 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 IM45_1229 5c9859ed63454b023bc2d288c7b9fce8 320 Gene3D G3DSA:3.40.50.11270 12 96 3.3E-107 T 12-10-2018 IM45_1229 5c9859ed63454b023bc2d288c7b9fce8 320 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 284 9.9E-96 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 IM45_1229 5c9859ed63454b023bc2d288c7b9fce8 320 Gene3D G3DSA:3.40.1010.20 97 196 3.3E-107 T 12-10-2018 IM45_1277 9c9cbe5bfaa6f727c3ef0edd634b4aab 96 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.142 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 IM45_1277 9c9cbe5bfaa6f727c3ef0edd634b4aab 96 Gene3D G3DSA:2.30.30.100 1 72 2.1E-34 T 12-10-2018 IM45_1277 9c9cbe5bfaa6f727c3ef0edd634b4aab 96 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 8.8E-30 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 IM45_1277 9c9cbe5bfaa6f727c3ef0edd634b4aab 96 SUPERFAMILY SSF50182 7 69 4.24E-24 T 12-10-2018 IPR010920 LSM domain superfamily IM45_1277 9c9cbe5bfaa6f727c3ef0edd634b4aab 96 Pfam PF17209 Hfq protein 7 68 8.3E-31 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 IM45_284 5cefd85b3a459d2f279a045e3b258da4 236 SUPERFAMILY SSF56300 1 221 4.75E-27 T 12-10-2018 IM45_284 5cefd85b3a459d2f279a045e3b258da4 236 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 197 4.5E-8 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 IM45_284 5cefd85b3a459d2f279a045e3b258da4 236 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 235 89.544 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 IM45_284 5cefd85b3a459d2f279a045e3b258da4 236 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 225 1.6E-77 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 IM45_1073 0a2347a8836c951fdd8191ea77494be3 246 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 2 240 6.5E-78 T 12-10-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 IM45_1073 0a2347a8836c951fdd8191ea77494be3 246 SUPERFAMILY SSF53474 4 241 3.91E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold IM45_1073 0a2347a8836c951fdd8191ea77494be3 246 Pfam PF00561 alpha/beta hydrolase fold 4 105 3.2E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 IM45_1073 0a2347a8836c951fdd8191ea77494be3 246 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 1 243 37.598 T 12-10-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 IM45_1073 0a2347a8836c951fdd8191ea77494be3 246 Gene3D G3DSA:3.40.50.1820 2 242 2.2E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold IM45_441 90cceebb838bcdf3d508760ab9bd106a 361 TIGRFAM TIGR02380 ECA_wecA: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 8 352 3.7E-146 T 12-10-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819|MetaCyc: PWY-7905 IM45_441 90cceebb838bcdf3d508760ab9bd106a 361 Hamap MF_02030 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase [wecA]. 9 355 26.724 T 12-10-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819|MetaCyc: PWY-7905 IM45_441 90cceebb838bcdf3d508760ab9bd106a 361 Pfam PF00953 Glycosyl transferase family 4 76 235 5.1E-28 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 IM45_421 adcd03cf43964ca1985202fa6e81d724 245 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 61 236 2.5E-63 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 IM45_421 adcd03cf43964ca1985202fa6e81d724 245 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 66 229 2.5E-48 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 IM45_049 6e7581b51ee85c283d081e05c051a503 282 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 63 85 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site IM45_049 6e7581b51ee85c283d081e05c051a503 282 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 7 281 5.4E-104 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 IM45_049 6e7581b51ee85c283d081e05c051a503 282 Pfam PF01040 UbiA prenyltransferase family 24 265 8.5E-59 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 IM45_049 6e7581b51ee85c283d081e05c051a503 282 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 1 282 28.505 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 IM45_049 6e7581b51ee85c283d081e05c051a503 282 Gene3D G3DSA:1.10.357.140 20 178 4.6E-41 T 12-10-2018 IM45_230 97888ab80565a3b4a64b1cf839f5209e 148 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 141 5.2E-20 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 IM45_230 97888ab80565a3b4a64b1cf839f5209e 148 Gene3D G3DSA:3.30.420.270 61 133 4.4E-23 T 12-10-2018 IM45_293 f6b4f26c7f923c2837bf68157b68a5b0 454 Pfam PF01295 Adenylate cyclase, class-I 244 447 7.5E-81 T 12-10-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 IM45_293 f6b4f26c7f923c2837bf68157b68a5b0 454 Pfam PF12633 Adenylate cyclase NT domain 23 216 1.6E-68 T 12-10-2018 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 IM45_104 c84ac8cb635c76ef7e6eede717be6111 253 Gene3D G3DSA:3.40.50.720 2 253 1.1E-89 T 12-10-2018 IM45_104 c84ac8cb635c76ef7e6eede717be6111 253 Pfam PF00899 ThiF family 10 246 6.1E-63 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 IM45_104 c84ac8cb635c76ef7e6eede717be6111 253 SUPERFAMILY SSF69572 3 251 1.24E-77 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 IM45_425 af0f4b0570807a984d98b4827183406e 446 Pfam PF06899 WzyE protein, O-antigen assembly polymerase 1 440 4.3E-203 T 12-10-2018 IPR010691 Probable ECA polymerase WzyE GO:0009246|GO:0016021 IM45_535 5bffa4ae422109198351d5f3d598b678 127 Gene3D G3DSA:3.30.160.150 1 105 1.6E-30 T 12-10-2018 IM45_303 ee02bc9dd466c2626851cc6c83466928 335 Pfam PF01594 AI-2E family transporter 13 327 3.7E-13 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like IM45_423 338fb04758b62245cf28b8634d3408e9 322 Pfam PF07429 4-alpha-L-fucosyltransferase glycosyl transferase group 56 1 317 2.1E-135 T 12-10-2018 IPR009993 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase GO:0008417|GO:0009246|GO:0036065 IM45_1061 7584b7b11d3e561005988096d4c4f1d8 186 Pfam PF02325 YGGT family 108 175 5.1E-8 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 IM45_1061 7584b7b11d3e561005988096d4c4f1d8 186 Pfam PF02325 YGGT family 12 78 1.1E-9 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 IM45_063 91e2eaf1b7d984bfa43e1cc2f9e8d4ea 225 Pfam PF09335 SNARE associated Golgi protein 41 165 1.2E-18 T 12-10-2018 IPR032816 SNARE associated Golgi protein IM45_1361 a6fbd5c15890ebaa42bb28d4fd96a992 111 Pfam PF04380 Membrane fusogenic activity 1 77 2.4E-23 T 12-10-2018 IPR007475 Membrane fusogenic activity