locus-tag	class	description
A1sIA105_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A1sIA105_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A1sIA105_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A1sIA105_00020	ENOG4105K7N	UPF0232 protein
A1sIA105_00025	ENOG4105CFG	Acts as a chaperone (By similarity)
A1sIA105_00030	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A1sIA105_00035	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A1sIA105_00040	ENOG4105KNI	merR family transcriptional Regulator
A1sIA105_00055	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A1sIA105_00065	ENOG4108HKT	sucrose-6-phosphate hydrolase
A1sIA105_00085	ENOG4105ETE	Transcriptional regulator (LacI family
A1sIA105_00090	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A1sIA105_00095	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A1sIA105_00115	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A1sIA105_00120	ENOG4107QRG	dna polymerase iii
A1sIA105_00165	ENOG4108IAJ	Nad-dependent epimerase dehydratase
A1sIA105_00170	ENOG4105E2K	Glycosyl transferase (Group 1
A1sIA105_00195	ENOG4107EF8	Glycosyl transferase (Group 1
A1sIA105_00200	ENOG4105BZ1	(ABC) transporter
A1sIA105_00205	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A1sIA105_00215	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
A1sIA105_00220	ENOG4105FAW	cDP-glucose 4,6-dehydratase
A1sIA105_00225	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A1sIA105_00265	ENOG4107QQG	Dehydrogenase
A1sIA105_00270	ENOG4105CMR	udp-glucose 4-epimerase
A1sIA105_00275	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A1sIA105_00280	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A1sIA105_00285	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A1sIA105_00300	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A1sIA105_00310	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A1sIA105_00330	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A1sIA105_00335	ENOG4107NHD	transcriptional regulator
A1sIA105_00350	ENOG4105I3K	Ferric uptake regulator, Fur family
A1sIA105_00355	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A1sIA105_00360	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
A1sIA105_00370	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A1sIA105_00380	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A1sIA105_00395	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A1sIA105_00400	ENOG4105C8N	cysteinyl-tRNA synthetase
A1sIA105_00405	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A1sIA105_00435	ENOG4105CGD	Nad-dependent epimerase dehydratase
A1sIA105_00445	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A1sIA105_00455	ENOG4105VEQ	Cold shock protein
A1sIA105_00470	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A1sIA105_00475	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A1sIA105_00485	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A1sIA105_00490	ENOG4105KHC	sulfurtransferase
A1sIA105_00500	ENOG4105BZU	Histidine kinase
A1sIA105_00510	ENOG4105C1J	atp-dependent rna helicase
A1sIA105_00515	ENOG4108IXY	short-chain dehydrogenase reductase
A1sIA105_00535	ENOG4107R13	MMPL domain protein
A1sIA105_00555	ENOG4105C1G	acyl-Coa dehydrogenase
A1sIA105_00560	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
A1sIA105_00570	ENOG4105KNA	-acetyltransferase
A1sIA105_00590	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A1sIA105_00595	ENOG4105F8V	Hydrolase, tatD family
A1sIA105_00600	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A1sIA105_00605	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A1sIA105_00620	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A1sIA105_00625	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A1sIA105_00630	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A1sIA105_00635	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A1sIA105_00640	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A1sIA105_00660	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A1sIA105_00690	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A1sIA105_00715	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A1sIA105_00735	ENOG4108IAB	Phoh family
A1sIA105_00745	ENOG4107GFK	fumarate
A1sIA105_00750	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A1sIA105_00755	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A1sIA105_00760	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A1sIA105_00775	ENOG4105CGY	Dna recombination protein
A1sIA105_00780	ENOG4105C3G	gtp-binding protein
A1sIA105_00785	ENOG4105CI3	gtp-binding protein typa
A1sIA105_00795	ENOG4105C4R	Atp-dependent dna helicase
A1sIA105_00800	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
A1sIA105_00825	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
A1sIA105_00850	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A1sIA105_00855	ENOG4105DJZ	UPF0182 protein
A1sIA105_00870	ENOG4107TK4	histidinol-phosphate phosphatase
A1sIA105_00875	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A1sIA105_00880	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A1sIA105_00885	ENOG4108RAV	Conserved protein
A1sIA105_00890	ENOG4105EMN	RNA polymerase sigma factor
A1sIA105_00905	ENOG4108VEQ	Superoxide dismutase
A1sIA105_00920	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A1sIA105_00925	ENOG4105CHR	reductase
A1sIA105_00975	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A1sIA105_00980	ENOG4105CAK	Cell division ATP-binding protein ftsE
A1sIA105_00985	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
A1sIA105_00990	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A1sIA105_01005	ENOG4105DBV	ornithine carbamoyltransferase
A1sIA105_01010	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A1sIA105_01015	ENOG4105W8H	transhydrogenase (subunit alpha
A1sIA105_01020	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A1sIA105_01025	ENOG4105EUB	pirin domain protein
A1sIA105_01030	ENOG4105C72	UPF0176 protein
A1sIA105_01050	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A1sIA105_01075	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A1sIA105_01080	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A1sIA105_01085	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A1sIA105_01095	ENOG4105EXC	Acyl-transferase
A1sIA105_01135	ENOG4105C75	arginyL-tRNA synthetase
A1sIA105_01145	ENOG4105D6E	homoserine dehydrogenase
A1sIA105_01150	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A1sIA105_01155	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A1sIA105_01165	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A1sIA105_01170	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A1sIA105_01175	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A1sIA105_01185	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A1sIA105_01190	ENOG4105ESV	Glycosyl transferase, family 4
A1sIA105_01205	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
A1sIA105_01210	ENOG4106DE0	ATP synthase
A1sIA105_01215	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
A1sIA105_01220	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A1sIA105_01225	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A1sIA105_01230	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A1sIA105_01235	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A1sIA105_01240	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A1sIA105_01275	ENOG4105CJ1	ABC, transporter
A1sIA105_01310	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A1sIA105_01345	ENOG4105CVJ	phosphoglycerate mutase
A1sIA105_01375	ENOG4105K4H	Nlp p60 protein
A1sIA105_01410	ENOG41061CK	Antibiotic biosynthesis monooxygenase
A1sIA105_01415	ENOG4105CXK	mandelate racemase muconate lactonizing
A1sIA105_01425	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
A1sIA105_01435	ENOG4105CHR	reductase
A1sIA105_01445	ENOG4106A3M	Cytochrome p-450
A1sIA105_01465	ENOG4105K5X	acetyltransferase
A1sIA105_01475	ENOG4105CXN	decarboxylase
A1sIA105_01490	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A1sIA105_01495	ENOG4105C9K	Endothelin-converting enzyme 1
A1sIA105_01515	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A1sIA105_01520	ENOG4105C4K	Nad synthetase
A1sIA105_01525	ENOG4105C5F	glutamine synthetase
A1sIA105_01535	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A1sIA105_01540	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
A1sIA105_01545	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A1sIA105_01560	ENOG4105PEJ	SchA CurD domain protein
A1sIA105_01565	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A1sIA105_01580	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A1sIA105_01600	ENOG4105C0H	protease
A1sIA105_01620	ENOG4108WQH	regulatoR
A1sIA105_01625	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A1sIA105_01630	ENOG4105BZU	Histidine kinase
A1sIA105_01635	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A1sIA105_01650	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A1sIA105_01660	ENOG4105D9R	oxidoreductase
A1sIA105_01675	ENOG4105EXW	epimerase dehydratase
A1sIA105_01685	ENOG41060NJ	transcriptional regulator
A1sIA105_01690	ENOG4105CXK	mandelate racemase muconate lactonizing
A1sIA105_01700	ENOG4105C2J	ABC transporter
A1sIA105_01705	ENOG4105CNN	ABC, transporter
A1sIA105_01735	ENOG4105VEQ	Cold shock protein
A1sIA105_01760	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A1sIA105_01765	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A1sIA105_01780	ENOG4108MJN	Glycosyl Transferase
A1sIA105_01785	ENOG4105BZF	Glycosyl transferase (Group 1
A1sIA105_01795	ENOG4105C10	Electron transfer flavoprotein
A1sIA105_01805	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A1sIA105_01810	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A1sIA105_01815	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A1sIA105_01820	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A1sIA105_01825	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A1sIA105_01835	ENOG4105C8T	Leucyl-tRNA synthetase
A1sIA105_01845	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A1sIA105_01850	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A1sIA105_01860	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A1sIA105_01865	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A1sIA105_01870	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A1sIA105_01880	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A1sIA105_01895	ENOG4105ERH	Fumarylacetoacetate hydrolase
A1sIA105_01900	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A1sIA105_01915	ENOG4105CQB	FAD linked oxidase domain protein
A1sIA105_01950	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
A1sIA105_01980	ENOG4105C2J	ABC transporter
A1sIA105_01985	ENOG4105CNN	ABC, transporter
A1sIA105_01990	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
A1sIA105_02000	ENOG4105CXK	mandelate racemase muconate lactonizing
A1sIA105_02005	ENOG4108R85	Short chain dehydrogenase
A1sIA105_02025	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A1sIA105_02035	ENOG4105DKQ	ROK family
A1sIA105_02040	ENOG4105CPQ	Dehydrogenase
A1sIA105_02050	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
A1sIA105_02060	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
A1sIA105_02065	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
A1sIA105_02070	ENOG4107TYG	Oxidoreductase domain-containing protein
A1sIA105_02075	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
A1sIA105_02140	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A1sIA105_02175	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A1sIA105_02180	ENOG41067Z0	domain protein
A1sIA105_02190	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A1sIA105_02195	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A1sIA105_02210	ENOG4108R6K	riboflavin synthase, subunit alpha
A1sIA105_02215	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A1sIA105_02220	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A1sIA105_02225	ENOG4105CPQ	Dehydrogenase
A1sIA105_02230	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A1sIA105_02245	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A1sIA105_02250	ENOG4108IJ9	(ABC) transporter
A1sIA105_02255	ENOG4108IJ9	(ABC) transporter
A1sIA105_02280	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A1sIA105_02300	ENOG4105C5I	Dehydrogenase
A1sIA105_02325	ENOG4105EHG	Permease protein
A1sIA105_02330	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A1sIA105_02350	ENOG4105DWV	Homoserine O-trans-acetylase
A1sIA105_02355	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A1sIA105_02370	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A1sIA105_02380	ENOG4105C5H	ABC transporter
A1sIA105_02390	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A1sIA105_02410	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A1sIA105_02415	ENOG4107QYR	Signal peptidase i
A1sIA105_02420	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A1sIA105_02430	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A1sIA105_02435	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A1sIA105_02440	ENOG4105FDR	Membrane
A1sIA105_02450	ENOG4105CTQ	phosphohexokinase
A1sIA105_02455	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
A1sIA105_02460	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A1sIA105_02465	ENOG4105C5W	Aldolase
A1sIA105_02475	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A1sIA105_02525	ENOG4105CND	Glycosyl transferase, family 2
A1sIA105_02565	ENOG4106UW1	Major Facilitator superfamily
A1sIA105_02585	ENOG4105C0B	DNA polymerase III (alpha subunit)
A1sIA105_02590	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A1sIA105_02600	ENOG4108V6E	Cell division protein mraZ
A1sIA105_02605	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A1sIA105_02615	ENOG4105CJN	penicillin-binding protein
A1sIA105_02620	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A1sIA105_02630	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A1sIA105_02635	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A1sIA105_02645	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A1sIA105_02650	ENOG4105DFU	Cell wall formation (By similarity)
A1sIA105_02660	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A1sIA105_02665	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A1sIA105_02670	ENOG4105DFA	alanine racemase domain protein
A1sIA105_02675	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
A1sIA105_02685	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A1sIA105_02690	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A1sIA105_02710	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A1sIA105_02720	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A1sIA105_02730	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A1sIA105_02735	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A1sIA105_02740	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A1sIA105_02745	ENOG4105CRQ	synthase (Component I)
A1sIA105_02750	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A1sIA105_02755	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A1sIA105_02760	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A1sIA105_02775	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A1sIA105_02785	ENOG4105CBC	glutamate synthase
A1sIA105_02815	ENOG4105C32	Amino acid ABC transporter (Permease)
A1sIA105_02820	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A1sIA105_02825	ENOG4105C0Z	ABC transporter
A1sIA105_02830	ENOG4108IV0	ABC, transporter
A1sIA105_02835	ENOG4105KA0	thioesterase Superfamily protein
A1sIA105_02850	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A1sIA105_02855	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A1sIA105_02860	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A1sIA105_02865	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A1sIA105_02870	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A1sIA105_02880	ENOG4105CIE	May be required for sporulation (By similarity)
A1sIA105_02885	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A1sIA105_02890	ENOG4105BZA	Phosphoglycerate kinase
A1sIA105_02920	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
A1sIA105_02940	ENOG4105VQD	rieske 2fe-2S domain-containing protein
A1sIA105_02945	ENOG4105C3K	feS assembly ATPase SufC
A1sIA105_02950	ENOG4105C9B	Cysteine desulfurase
A1sIA105_02955	ENOG4108UNV	SUF system FeS assembly protein, NifU family
A1sIA105_02960	ENOG4105VG1	fes assembly suf system protein
A1sIA105_02965	ENOG4105BZ1	(ABC) transporter
A1sIA105_02985	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A1sIA105_02990	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A1sIA105_03000	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A1sIA105_03005	ENOG4108RWN	rrna methyltransferase
A1sIA105_03010	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A1sIA105_03015	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A1sIA105_03020	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A1sIA105_03025	ENOG4105CAS	nag kinase
A1sIA105_03030	ENOG4105C8Y	Acetylornithine aminotransferase
A1sIA105_03040	ENOG4105CH7	arginosuccinase
A1sIA105_03045	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A1sIA105_03085	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A1sIA105_03090	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A1sIA105_03095	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A1sIA105_03115	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A1sIA105_03120	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A1sIA105_03140	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A1sIA105_03145	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A1sIA105_03150	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A1sIA105_03175	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A1sIA105_03180	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A1sIA105_03185	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A1sIA105_03190	ENOG4105HFS	5'-3' exonuclease
A1sIA105_03205	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A1sIA105_03215	ENOG4107TMB	Transcriptional regulator
A1sIA105_03235	ENOG4105C3R	Methionine synthase
A1sIA105_03245	ENOG4105C8N	cysteinyl-tRNA synthetase
A1sIA105_03265	ENOG4105CPC	Aldo Keto reductase
A1sIA105_03270	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A1sIA105_03280	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A1sIA105_03285	ENOG4107W53	thymidine kinase
A1sIA105_03290	ENOG4108UQV	Membrane
A1sIA105_03295	ENOG4108VW9	Membrane
A1sIA105_03300	ENOG4105C7N	Xanthine uracil vitamin C permease
A1sIA105_03305	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A1sIA105_03310	ENOG4105DKW	ABC transporter
A1sIA105_03315	ENOG4105EAC	phosphoserine phosphatase
A1sIA105_03320	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A1sIA105_03325	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
A1sIA105_03330	ENOG4105DJV	ribulose-phosphate 3-epimerase
A1sIA105_03340	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A1sIA105_03345	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A1sIA105_03350	ENOG4105C25	Primosomal protein n'
A1sIA105_03355	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A1sIA105_03365	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A1sIA105_03370	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A1sIA105_03375	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A1sIA105_03380	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A1sIA105_03385	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A1sIA105_03390	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A1sIA105_03395	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A1sIA105_03400	ENOG4105CD3	dihydroorotase
A1sIA105_03405	ENOG4105CXT	aspartate transcarbamylase
A1sIA105_03410	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A1sIA105_03420	ENOG410803B	Involved in the transcription termination process (By similarity)
A1sIA105_03425	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A1sIA105_03430	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A1sIA105_03440	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A1sIA105_03445	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A1sIA105_03455	ENOG4105E2X	shikimate dehydrogenase
A1sIA105_03465	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A1sIA105_03470	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A1sIA105_03480	ENOG4105C9M	aspartyl-trna synthetase
A1sIA105_03485	ENOG4105CUT	histidyl-tRNA synthetase
A1sIA105_03490	ENOG4105C5X	domain protein
A1sIA105_03495	ENOG4105C99	atpase involved in dna repair
A1sIA105_03500	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A1sIA105_03505	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A1sIA105_03510	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A1sIA105_03515	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A1sIA105_03520	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A1sIA105_03525	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A1sIA105_03530	ENOG4105CDY	transcriptional regulatory protein
A1sIA105_03535	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A1sIA105_03540	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A1sIA105_03555	ENOG4105E2K	Glycosyl transferase (Group 1
A1sIA105_03560	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
A1sIA105_03580	ENOG4105C22	threonyL-tRNA synthetase
A1sIA105_03605	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
A1sIA105_03625	ENOG4107Y9U	Membrane
A1sIA105_03635	ENOG4105CTU	Proline racemase
A1sIA105_03680	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A1sIA105_03690	ENOG4105CCU	oxidase (Subunit III)
A1sIA105_03695	ENOG4107UDY	cytochrome C
A1sIA105_03700	ENOG4107EUI	c reductase, iron-sulfur
A1sIA105_03705	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A1sIA105_03715	ENOG4105MCD	Part of cytochrome c oxidase, its function is
A1sIA105_03720	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A1sIA105_03725	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
A1sIA105_03745	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A1sIA105_03755	ENOG4105CPC	Aldo Keto reductase
A1sIA105_03770	ENOG4105BZ1	(ABC) transporter
A1sIA105_03780	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A1sIA105_03785	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A1sIA105_03800	ENOG4105ECP	epimerase
A1sIA105_03805	ENOG4108QDE	fad dependent oxidoreductase
A1sIA105_03810	ENOG4105EYF	MMPL domain protein
A1sIA105_03815	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A1sIA105_03820	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A1sIA105_03825	ENOG4105E9Q	Acyl-transferase
A1sIA105_03845	ENOG4105C5F	glutamine synthetase
A1sIA105_03855	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A1sIA105_03870	ENOG41060WC	Enoyl-CoA hydratase
A1sIA105_03890	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A1sIA105_03900	ENOG4105DKQ	ROK family
A1sIA105_03920	ENOG4105WH1	Two component transcriptional regulator luxr family
A1sIA105_03925	ENOG4105JNK	Glycosyl transferase (Group 1
A1sIA105_03930	ENOG4107SN7	NLP P60 protein
A1sIA105_03950	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A1sIA105_03960	ENOG4105CHU	acetyl-coa acetyltransferase
A1sIA105_03965	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A1sIA105_03970	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A1sIA105_03975	ENOG4107QM5	aconitate hydratase
A1sIA105_03980	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A1sIA105_03985	ENOG4107VEG	TrkA-N domain protein
A1sIA105_04000	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A1sIA105_04020	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A1sIA105_04025	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A1sIA105_04030	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A1sIA105_04035	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A1sIA105_04045	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A1sIA105_04050	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A1sIA105_04055	ENOG41082KU	UPF0109 protein
A1sIA105_04060	ENOG4105K5M	30s ribosomal protein S16
A1sIA105_04065	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A1sIA105_04070	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A1sIA105_04085	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A1sIA105_04095	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A1sIA105_04110	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A1sIA105_04115	ENOG4106H78	methyltransferase
A1sIA105_04125	ENOG4105VB9	50S ribosomal protein l28
A1sIA105_04140	ENOG4105CPF	Cell wall formation (By similarity)
A1sIA105_04145	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A1sIA105_04155	ENOG4105K70	DNA-binding protein
A1sIA105_04160	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A1sIA105_04165	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A1sIA105_04175	ENOG4105KC9	Modulates RecA activity (By similarity)
A1sIA105_04180	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A1sIA105_04200	ENOG4105WBV	Transcriptional regulator
A1sIA105_04205	ENOG4105CEV	competence damage-inducible protein
A1sIA105_04215	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A1sIA105_04225	ENOG4107QZI	cell division protein FtsK
A1sIA105_04235	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A1sIA105_04260	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A1sIA105_04265	ENOG4105C1V	Peptidase, M16
A1sIA105_04270	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A1sIA105_04275	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A1sIA105_04285	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A1sIA105_04290	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A1sIA105_04295	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A1sIA105_04295	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A1sIA105_04305	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
A1sIA105_04315	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A1sIA105_04320	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A1sIA105_04325	ENOG4105DZP	Membrane-associated zinc metalloprotease
A1sIA105_04335	ENOG4105CYW	agmatinase
A1sIA105_04345	ENOG4105F38	ABC transporter, permease
A1sIA105_04350	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A1sIA105_04360	ENOG4105C26	Dehydrogenase
A1sIA105_04370	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A1sIA105_04380	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A1sIA105_04385	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A1sIA105_04390	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A1sIA105_04395	ENOG4105CE9	30S ribosomal protein S2
A1sIA105_04400	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A1sIA105_04415	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A1sIA105_04420	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A1sIA105_04425	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A1sIA105_04430	ENOG4108JQ1	Dehydrogenase
A1sIA105_04435	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A1sIA105_04440	ENOG4108ZP8	Acetolactate synthase small subunit
A1sIA105_04450	ENOG4105C01	Dihydroxy-acid dehydratase
A1sIA105_04460	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A1sIA105_04465	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A1sIA105_04470	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A1sIA105_04475	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A1sIA105_04480	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A1sIA105_04485	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A1sIA105_04490	ENOG4105K46	50S ribosomal protein l27
A1sIA105_04495	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A1sIA105_04500	ENOG4105C03	ribonuclease
A1sIA105_04505	ENOG4105CNI	cell division protein FtsW
A1sIA105_04525	ENOG4105DFF	Rod shape-determining protein mreb
A1sIA105_04530	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A1sIA105_04540	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A1sIA105_04545	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A1sIA105_04550	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A1sIA105_04560	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A1sIA105_04565	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A1sIA105_04570	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A1sIA105_04595	ENOG4108YZG	isomerase
A1sIA105_04600	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A1sIA105_04620	ENOG4105D8X	mechanosensitive ion channel
A1sIA105_04635	ENOG4108TGP	Thioesterase superfamily protein
A1sIA105_04655	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A1sIA105_04670	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A1sIA105_04680	ENOG4105F0N	pyrophosphate phospho-hydrolase
A1sIA105_04695	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A1sIA105_04710	ENOG4105CHR	reductase
A1sIA105_04715	ENOG4105CHR	reductase
A1sIA105_04725	ENOG4105C2J	ABC transporter
A1sIA105_04740	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A1sIA105_04745	ENOG4108RVA	ribokinase
A1sIA105_04750	ENOG4105EN6	Membrane
A1sIA105_04760	ENOG4105CG3	alpha amylase, catalytic region
A1sIA105_04770	ENOG4105CDH	Citrulline--aspartate ligase
A1sIA105_04780	ENOG4105BZU	Histidine kinase
A1sIA105_04785	ENOG4105ETX	regulatoR
A1sIA105_04810	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A1sIA105_04850	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A1sIA105_04855	ENOG4105MJ2	Competence protein
A1sIA105_04860	ENOG4105BZU	Histidine kinase
A1sIA105_04865	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A1sIA105_04870	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A1sIA105_04875	ENOG4107QKV	phosphomannomutase
A1sIA105_04890	ENOG4107RGC	Glycosyl transferase, family 2
A1sIA105_04895	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
A1sIA105_04910	ENOG4108Z4U	Ferredoxin
A1sIA105_04915	ENOG4105C8N	cysteinyl-tRNA synthetase
A1sIA105_04925	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
A1sIA105_04945	ENOG4105C1J	atp-dependent rna helicase
A1sIA105_04955	ENOG4105DB7	PHP domain protein
A1sIA105_04965	ENOG4105CJW	magnesium transporter
A1sIA105_04980	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A1sIA105_04990	ENOG4107ZBN	O-methyltransferase
A1sIA105_04995	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A1sIA105_05015	ENOG4108URH	decarboxylase
A1sIA105_05020	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
A1sIA105_05030	ENOG4105EY8	ABC transporter
A1sIA105_05045	ENOG4107TB5	TRANSCRIPTIONal
A1sIA105_05050	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A1sIA105_05055	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A1sIA105_05070	ENOG4105D8K	carboxyl transferase
A1sIA105_05080	ENOG4107WR6	Maf-like protein
A1sIA105_05085	ENOG4108JIK	carboxylase
A1sIA105_05095	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
A1sIA105_05105	ENOG4105C26	Dehydrogenase
A1sIA105_05110	ENOG4105C26	Dehydrogenase
A1sIA105_05115	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A1sIA105_05135	ENOG4105UIB	(ABC) transporter
A1sIA105_05140	ENOG4108JQ9	ABC transporter
A1sIA105_05145	ENOG4105DIH	basic membrane
A1sIA105_05155	ENOG4105C31	Tryptophanyl-tRNA synthetase
A1sIA105_05190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A1sIA105_05195	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A1sIA105_05215	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A1sIA105_05225	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
A1sIA105_05235	ENOG4105E39	Enoyl-CoA hydratase
A1sIA105_05240	ENOG4105JXH	GntR family transcriptional regulator
A1sIA105_05250	ENOG4105E39	Enoyl-CoA hydratase
A1sIA105_05265	ENOG4105CXK	mandelate racemase muconate lactonizing
A1sIA105_05270	ENOG4108UHU	Aldolase
A1sIA105_05285	ENOG4105F5R	ABC transporter
A1sIA105_05290	ENOG4105C2J	ABC transporter
A1sIA105_05300	ENOG4106517	Short-chain dehydrogenase reductase Sdr
A1sIA105_05315	ENOG4105CHR	reductase
A1sIA105_05325	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A1sIA105_05330	ENOG4105C01	Dihydroxy-acid dehydratase
A1sIA105_05335	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
A1sIA105_05340	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A1sIA105_05345	ENOG4107QVP	Dehydrogenase
A1sIA105_05360	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
A1sIA105_05370	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A1sIA105_05375	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A1sIA105_05380	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A1sIA105_05390	ENOG4108097	ATP-binding protein
A1sIA105_05410	ENOG4105C32	Amino acid ABC transporter (Permease)
A1sIA105_05415	ENOG4108IV0	ABC, transporter
A1sIA105_05420	ENOG4105C0Z	ABC transporter
A1sIA105_05425	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A1sIA105_05430	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A1sIA105_05440	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A1sIA105_05445	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A1sIA105_05450	ENOG4108UJD	30S ribosomal protein S9
A1sIA105_05455	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A1sIA105_05460	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A1sIA105_05465	ENOG4108ZT0	50S ribosomal protein l17
A1sIA105_05470	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A1sIA105_05475	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A1sIA105_05480	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A1sIA105_05485	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A1sIA105_05490	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A1sIA105_05500	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A1sIA105_05510	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A1sIA105_05515	ENOG410849U	50S ribosomal protein L30
A1sIA105_05520	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A1sIA105_05525	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A1sIA105_05530	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A1sIA105_05535	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A1sIA105_05540	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A1sIA105_05545	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A1sIA105_05550	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A1sIA105_05555	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A1sIA105_05560	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A1sIA105_05565	ENOG41082SA	50s ribosomal protein l29
A1sIA105_05570	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A1sIA105_05575	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A1sIA105_05580	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A1sIA105_05585	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A1sIA105_05595	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A1sIA105_05600	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A1sIA105_05605	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A1sIA105_05610	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A1sIA105_05615	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A1sIA105_05620	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A1sIA105_05625	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A1sIA105_05630	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A1sIA105_05645	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A1sIA105_05650	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A1sIA105_05655	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A1sIA105_05665	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A1sIA105_05670	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A1sIA105_05695	ENOG4107R4N	Cell wall formation (By similarity)
A1sIA105_05710	ENOG410900P	UPF0336 protein
A1sIA105_05715	ENOG4105WDJ	50S ribosomal protein L33
A1sIA105_05735	ENOG4105K4P	CoA-binding domain protein
A1sIA105_05740	ENOG4105E0X	reductase
A1sIA105_05755	ENOG4105CDA	abc transporter atp-binding protein
A1sIA105_05760	ENOG4105E5Q	amino acid AbC transporter
A1sIA105_05765	ENOG4105EAB	amino acid AbC transporter
A1sIA105_05775	ENOG4108VPT	UPF0234 protein
A1sIA105_05790	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A1sIA105_05805	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A1sIA105_05810	ENOG4105DF2	NADH dehydrogenase subunit j
A1sIA105_05815	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A1sIA105_05820	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A1sIA105_05825	ENOG4108IEH	NADH dehydrogenase subunit g
A1sIA105_05830	ENOG4107QIZ	NADH dehydrogenase
A1sIA105_05840	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A1sIA105_05845	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A1sIA105_05850	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A1sIA105_05860	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A1sIA105_05865	ENOG4107ZYJ	bioY protein
A1sIA105_05870	ENOG4105E4F	Isochorismate synthase
A1sIA105_05875	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A1sIA105_05880	ENOG4107TCW	O-succinylbenzoate synthase
A1sIA105_05885	ENOG4108IPT	Naphthoate synthase
A1sIA105_05905	ENOG4105CRE	cytochrome C
A1sIA105_05910	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
A1sIA105_05915	ENOG4107QIV	Cytochrome c biogenesis protein
A1sIA105_05920	ENOG4107QX9	Thiol disulfide interChange protein
A1sIA105_05925	ENOG4108RH7	phosphoglycerate mutase
A1sIA105_05930	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
A1sIA105_05945	ENOG4105CFI	type iii restriction protein res subunit
A1sIA105_05965	ENOG4105II7	pyrroline-5-carboxylate reductase
A1sIA105_05970	ENOG4108JWX	
A1sIA105_05975	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A1sIA105_05980	ENOG4105CEN	a g-specific adenine glycosylase
A1sIA105_05985	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A1sIA105_05995	ENOG4105CRK	lysyL-tRNA synthetase
A1sIA105_06000	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
A1sIA105_06010	ENOG4108IYU	L-aspartate oxidase
A1sIA105_06015	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A1sIA105_06020	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A1sIA105_06030	ENOG4105EEI	dihydropteroate synthase
A1sIA105_06035	ENOG4105EUJ	GTP cyclohydrolase i
A1sIA105_06050	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A1sIA105_06055	ENOG4105K4H	Nlp p60 protein
A1sIA105_06075	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A1sIA105_06105	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
A1sIA105_06115	ENOG4108YZP	cobalt ABC transporter, inner membrane subunit CbiQ
A1sIA105_06120	ENOG4108JJB	ABC transporter
A1sIA105_06135	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A1sIA105_06140	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A1sIA105_06170	ENOG4105ESV	Glycosyl transferase, family 4
A1sIA105_06205	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
A1sIA105_06210	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A1sIA105_06215	ENOG410839H	phosphoribosylformylglycinamidine synthase
A1sIA105_06220	ENOG4105C8V	SAICAR synthetase
A1sIA105_06225	ENOG4105C83	adenylosuccinate lyase
A1sIA105_06230	ENOG4105C12	Phosphoribosylglycinamide synthetase
A1sIA105_06235	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A1sIA105_06240	ENOG4107RCW	fructose-bisphosphate aldolase
A1sIA105_06245	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A1sIA105_06255	ENOG4107ZT5	Thiol disulfide interchange protein
A1sIA105_06270	ENOG4105KME	endoribonuclease L-psp
A1sIA105_06275	ENOG4105KTH	gatB Yqey
A1sIA105_06305	ENOG4105CFH	Aspartokinase
A1sIA105_06310	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A1sIA105_06355	ENOG4105C0X	amino acid
A1sIA105_06360	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A1sIA105_06370	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A1sIA105_06380	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
A1sIA105_06390	ENOG4105C5H	ABC transporter
A1sIA105_06395	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
A1sIA105_06400	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
A1sIA105_06405	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A1sIA105_06425	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A1sIA105_06435	ENOG410635A	Membrane
A1sIA105_06440	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A1sIA105_06455	ENOG4105EQH	reductase
A1sIA105_06460	ENOG4105ETE	Transcriptional regulator (LacI family
A1sIA105_06465	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
A1sIA105_06480	ENOG4105DET	Rhamnulokinase
A1sIA105_06490	ENOG4105CXK	mandelate racemase muconate lactonizing
A1sIA105_06495	ENOG4105CHR	reductase
A1sIA105_06510	ENOG4105CHR	reductase
A1sIA105_06520	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A1sIA105_06525	ENOG4105CPP	Dehydrogenase, E1 component
A1sIA105_06530	ENOG4107RUY	(E1 component), alpha subunit
A1sIA105_06535	ENOG4105C7S	Dehydrogenase
A1sIA105_06540	ENOG4105DTQ	mandelate racemase muconate lactonizing
A1sIA105_06545	ENOG4105ETE	Transcriptional regulator (LacI family
A1sIA105_06550	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
A1sIA105_06555	ENOG4105CNN	ABC, transporter
A1sIA105_06560	ENOG4105C2J	ABC transporter
A1sIA105_06570	ENOG4105DTQ	mandelate racemase muconate lactonizing
A1sIA105_06575	ENOG4105ETE	Transcriptional regulator (LacI family
A1sIA105_06585	ENOG4105CK5	oxidoreductase
A1sIA105_06615	ENOG4107T6F	Xaa-Pro aminopeptidase
A1sIA105_06620	ENOG4105WMR	Protein CrcB homolog
A1sIA105_06625	ENOG41084I6	Protein CrcB homolog
A1sIA105_06650	ENOG410667J	hydrolase
A1sIA105_06655	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A1sIA105_06660	ENOG4105CQC	Prephenate dehydratase
A1sIA105_06695	ENOG4105DF6	Fe-S oxidoreductase
A1sIA105_06700	ENOG4107ZXI	Rhomboid family
A1sIA105_06715	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A1sIA105_06720	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A1sIA105_06725	ENOG4105D0M	Protease HtpX homolog
A1sIA105_06730	ENOG4108V0P	LemA family
A1sIA105_06735	ENOG4105DHP	deoxycytidine triphosphate deaminase
A1sIA105_06740	ENOG4105CSU	acyl-Coa dehydrogenase
A1sIA105_06750	ENOG4105CDU	Replicative dna helicase
A1sIA105_06755	ENOG4105D7N	magnesium and cobalt transport protein CorA
A1sIA105_06760	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A1sIA105_06765	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A1sIA105_06775	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
A1sIA105_06785	ENOG4105BZ4	penicillin-binding protein
A1sIA105_06800	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A1sIA105_06820	ENOG4105C3M	thioredoxin reductase
A1sIA105_06825	ENOG4105K63	Thioredoxin
A1sIA105_06830	ENOG4108E1C	hydrolase
A1sIA105_06835	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A1sIA105_06845	ENOG4107QJE	Chromosome Partitioning Protein
A1sIA105_06850	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A1sIA105_06860	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A1sIA105_06865	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A1sIA105_06870	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A1sIA105_06875	ENOG41084CH	50S ribosomal protein l34