locus-tag	class	description
SULMSEV_001	COG0321	lipoyl(octanoyl) transferase activity
SULMSEV_002	COG0525	valine-tRNA ligase activity
SULMSEV_003	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SULMSEV_006	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SULMSEV_007	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SULMSEV_011	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SULMSEV_014	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULMSEV_017	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SULMSEV_019	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SULMSEV_020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SULMSEV_025	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SULMSEV_026	COG0356	it plays a direct role in the translocation of protons across the membrane
SULMSEV_027	COG0527	aspartate kinase activity
SULMSEV_027	COG0460	homoserine dehydrogenase
SULMSEV_028	COG2095	MarC family integral membrane protein
SULMSEV_029	COG0473	3-isopropylmalate dehydrogenase activity
SULMSEV_031	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SULMSEV_032	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULMSEV_033	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SULMSEV_034	COG0495	leucyl-tRNA aminoacylation
SULMSEV_036	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULMSEV_037	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SULMSEV_042	COG0564	pseudouridine synthase activity
SULMSEV_043	COG0101	tRNA pseudouridine synthase activity
SULMSEV_046	COG0222	ribosome binding
SULMSEV_047	COG0081	regulation of translation
SULMSEV_055	COG2166	iron-sulfur cluster assembly
SULMSEV_062	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SULMSEV_063	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SULMSEV_067	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SULMSEV_068	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SULMSEV_074	COG2171	N-acyltransferase activity
SULMSEV_076	COG0617	tRNA 3'-terminal CCA addition
SULMSEV_078	COG0484	heat shock protein binding
SULMSEV_079	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SULMSEV_080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULMSEV_081	COG1363	Peptidase, m42
SULMSEV_086	COG0137	argininosuccinate synthase activity
SULMSEV_089	COG0505	Belongs to the CarA family
SULMSEV_090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SULMSEV_091	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SULMSEV_092	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SULMSEV_096	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SULMSEV_097	COG0037	tRNA processing
SULMSEV_099	COG0133	tryptophan synthase activity
SULMSEV_100	COG0134	indole-3-glycerol-phosphate synthase activity
SULMSEV_101	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SULMSEV_102	COG0512	Glutamine amidotransferase of anthranilate synthase
SULMSEV_102	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SULMSEV_103	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SULMSEV_104	COG1104	cysteine desulfurase activity
SULMSEV_109	COG0326	Molecular chaperone. Has ATPase activity
SULMSEV_110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULMSEV_112	COG0335	large ribosomal subunit rRNA binding
SULMSEV_113	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SULMSEV_114	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SULMSEV_115	COG0083	homoserine kinase activity
SULMSEV_116	COG0460	homoserine dehydrogenase
SULMSEV_116	COG0527	aspartate kinase activity
SULMSEV_122	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SULMSEV_124	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULMSEV_124	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULMSEV_125	COG0180	Tryptophanyl-tRNA synthetase
SULMSEV_127	COG0017	Asparaginyl-tRNA synthetase
SULMSEV_134	COG0360	Binds together with S18 to 16S ribosomal RNA
SULMSEV_140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SULMSEV_141	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SULMSEV_142	COG0681	Belongs to the peptidase S26 family
SULMSEV_144	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SULMSEV_146	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULMSEV_150	COG0567	Dehydrogenase, E1 component
SULMSEV_151	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULMSEV_152	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SULMSEV_153	COG2151	metal-sulfur cluster biosynthetic enzyme
SULMSEV_158	COG0719	Fe-S assembly protein
SULMSEV_159	COG0396	ATPase activity
SULMSEV_160	COG0719	Fe-S assembly protein
SULMSEV_162	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SULMSEV_163	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SULMSEV_164	COG0077	Prephenate dehydratase
SULMSEV_165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SULMSEV_171	COG0436	Aminotransferase
SULMSEV_172	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SULMSEV_173	COG0022	dehydrogenase e1 component
SULMSEV_173	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULMSEV_177	COG0254	rRNA binding
SULMSEV_181	COG0051	transcription antitermination factor activity, RNA binding
SULMSEV_183	COG0088	Forms part of the polypeptide exit tunnel
SULMSEV_193	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SULMSEV_198	COG0200	Binds to the 23S rRNA
SULMSEV_199	COG0201	protein transport
SULMSEV_200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SULMSEV_205	COG0202	RNA polymerase activity
SULMSEV_206	COG0203	ribosomal protein L17
SULMSEV_207	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SULMSEV_212	COG0165	Argininosuccinate lyase
SULMSEV_214	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SULMSEV_215	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULMSEV_216	COG0861	Integral membrane protein TerC family
SULMSEV_219	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SULMSEV_220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SULMSEV_221	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SULMSEV_223	COG0028	Belongs to the TPP enzyme family
SULMSEV_224	COG0129	dihydroxy-acid dehydratase activity