locus-tag	class	description
BN424_1	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BN424_1000	ENOG4105C8I	hydrolase, family 38
BN424_1001	ENOG4105CK1	PTS System
BN424_1007	ENOG4105E90	ABC transporter
BN424_1008	ENOG4108IJ8	ABC transporter
BN424_1009	ENOG4105DRP	amino acid AbC transporter
BN424_1010	ENOG4105EAD	ABC transporter
BN424_1011	ENOG4105CT1	(ABC) transporter
BN424_1012	ENOG4105CDA	abc transporter atp-binding protein
BN424_1013	ENOG4105C5H	ABC transporter
BN424_1014	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BN424_1015	ENOG4107R8B	5'-nucleotidase
BN424_1016	ENOG4105MMD	transcriptional regulator
BN424_1017	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
BN424_1019	ENOG4108W5N	phosphatidylglycerophosphatase a
BN424_1021	ENOG4105CAY	ferredoxin--nadp reductase
BN424_1023	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BN424_1024	ENOG4105EVU	fructokinase
BN424_1025	ENOG4105C87	Aminotransferase class I and II
BN424_1028	ENOG4107QYV	phosphohexose isomerase
BN424_104	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
BN424_1057	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BN424_1058	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BN424_1060	ENOG4105N5T	Radical SAM Protein
BN424_1061	ENOG410605W	Major Facilitator
BN424_1062	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BN424_1067	ENOG4107X35	defense response to bacterium
BN424_1071	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BN424_1072	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BN424_1073	ENOG4105WH5	Teichoic acid glycosylation protein
BN424_1076	ENOG4105C8T	Leucyl-tRNA synthetase
BN424_1080	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN424_1081	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BN424_1082	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BN424_1086	ENOG4105C28	cystathionine
BN424_1087	ENOG4105EAB	amino acid AbC transporter
BN424_1088	ENOG4105DRP	amino acid AbC transporter
BN424_1089	ENOG4105CDA	abc transporter atp-binding protein
BN424_1090	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BN424_1095	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BN424_1096	ENOG4107QSE	Dipeptidase
BN424_1097	ENOG4108I6A	alcohol dehydrogenase
BN424_1098	ENOG4108I6A	alcohol dehydrogenase
BN424_1099	ENOG4105KT7	mgtC SapB transporter
BN424_11	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BN424_1101	ENOG4105DHI	Methyltransferase
BN424_1102	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BN424_1103	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BN424_1105	ENOG4105C7N	Xanthine uracil vitamin C permease
BN424_111	ENOG4108IMY	Transcriptional regulator
BN424_1110	ENOG4105C75	arginyL-tRNA synthetase
BN424_1111	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
BN424_1115	ENOG4105C37	(CBS) domain
BN424_1116	ENOG4105BZ4	penicillin-binding protein
BN424_1118	ENOG4107VRP	DNA repair exonuclease
BN424_1119	ENOG4106D4I	domain protein
BN424_1122	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
BN424_1124	ENOG4105K59	histidine triad (HIT) protein
BN424_1129	ENOG4108V15	phosphotransferase enzyme family
BN424_1130	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BN424_1134	ENOG4107YZX	Universal stress protein
BN424_1135	ENOG4108VDD	TRNA binding domain protein
BN424_1138	ENOG4105DFU	Cell wall formation (By similarity)
BN424_1142	ENOG4105C2M	dna polymerase I
BN424_1143	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BN424_1144	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BN424_1145	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BN424_1148	ENOG4105C22	threonyL-tRNA synthetase
BN424_1149	ENOG4108ZJ4	polysaccharide deacetylase
BN424_1150	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BN424_1151	ENOG4105VJV	50s ribosomal protein L35
BN424_1152	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BN424_1162	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BN424_1163	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
BN424_1164	ENOG4105EWM	Histidine kinase
BN424_1165	ENOG4105CJZ	response regulator
BN424_1166	ENOG4105C19	ABC transporter
BN424_1168	ENOG4108J59	Extracellular solute-binding protein, family 5
BN424_1169	ENOG4108J59	Extracellular solute-binding protein, family 5
BN424_1171	ENOG4108Z3G	3H domain protein
BN424_1172	ENOG4105RNB	
BN424_1173	ENOG4105C3F	Signal peptidase i
BN424_1174	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
BN424_1175	ENOG4105CQW	ribosome biogenesis GTPase YqeH
BN424_1176	ENOG410812S	Rna-binding protein
BN424_1177	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BN424_1178	ENOG4108WF2	Metal Dependent Phosphohydrolase
BN424_1180	ENOG4105DXX	methyltransferase
BN424_1181	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BN424_1182	ENOG4105CDE	UPF0348 protein
BN424_1184	ENOG41067VY	50S ribosomal protein L32
BN424_1186	ENOG4108V6E	Cell division protein mraZ
BN424_1187	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BN424_1189	ENOG4105CJN	penicillin-binding protein
BN424_1190	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BN424_1192	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BN424_1193	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BN424_1194	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
BN424_1195	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BN424_1197	ENOG4105DFA	alanine racemase domain protein
BN424_1198	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BN424_1199	ENOG4108VIA	integral membrane protein
BN424_1200	ENOG4105DBK	s4 domain protein
BN424_1202	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BN424_1203	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BN424_1206	ENOG4105CJ1	ABC, transporter
BN424_1208	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BN424_1209	ENOG4105VEQ	Cold shock protein
BN424_1211	ENOG4107FQX	Alpha-acetolactate decarboxylase
BN424_1213	ENOG4107VKM	6-phosphogluconolactonase
BN424_1215	ENOG4107BMA	Transglycosylase associated protein
BN424_1216	ENOG4105CDW	Resistance protein
BN424_1218	ENOG4108YZ4	nudix hydrolase
BN424_1220	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BN424_1225	ENOG4106GSS	Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity)
BN424_125	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BN424_1253	ENOG4105F7F	Chaperone
BN424_126	ENOG4105D7N	magnesium and cobalt transport protein CorA
BN424_1260	ENOG4105BZ1	(ABC) transporter
BN424_1261	ENOG4108JJB	ABC transporter
BN424_1262	ENOG4108Z86	Glutamine amidotransferase
BN424_1263	ENOG4108J59	Extracellular solute-binding protein, family 5
BN424_1267	ENOG4105DHS	permease protein
BN424_1268	ENOG4105CM4	permease protein
BN424_1269	ENOG4108IPW	abc transporter atp-binding protein
BN424_127	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BN424_1271	ENOG4108WQ8	UPF0637 protein
BN424_1274	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BN424_1279	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
BN424_128	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BN424_1280	ENOG4105C3J	Cysteine desulfurase
BN424_1281	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BN424_1282	ENOG4105EFZ	amidohydrolase
BN424_1283	ENOG4105EFZ	amidohydrolase
BN424_1284	ENOG4108YWR	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
BN424_1285	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BN424_1287	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BN424_1288	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BN424_1289	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
BN424_129	ENOG4108EQA	pts system
BN424_1290	ENOG4105W5Q	DNA repair protein (RadC
BN424_1292	ENOG4105DFF	Rod shape-determining protein mreb
BN424_1293	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BN424_1296	ENOG4107QMS	site-determining protein
BN424_1297	ENOG4108HW3	(ABC) transporter
BN424_1298	ENOG4105EAB	amino acid AbC transporter
BN424_1299	ENOG4105E5Q	amino acid AbC transporter
BN424_1300	ENOG4105CDA	abc transporter atp-binding protein
BN424_1301	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BN424_1303	ENOG4105K46	50S ribosomal protein l27
BN424_1304	ENOG4107KJX	Transcriptional regulator
BN424_1305	ENOG4105DU0	nucleoside hydrolase
BN424_1306	ENOG4105CEE	C4-dicarboxylate transporter
BN424_1308	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BN424_1309	ENOG4107YZX	Universal stress protein
BN424_131	ENOG4105ETZ	PTS System
BN424_1312	ENOG4105D1H	recombination factor protein RarA
BN424_1314	ENOG41067MG	lrgb family
BN424_1319	ENOG4105D9M	gamma-glutamylcysteine synthetase
BN424_132	ENOG4105F3R	pts system mannose fructose sorbose family iid
BN424_1322	ENOG4105C3J	Cysteine desulfurase
BN424_1324	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BN424_1326	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN424_1328	ENOG4105C7H	Helicase, RecD TraA family
BN424_1329	ENOG4108QVC	Component IIC
BN424_1336	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BN424_1338	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BN424_1339	ENOG4105VPH	UPF0473 protein
BN424_134	ENOG4105CS2	ec 3.2.1.21
BN424_1342	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BN424_1344	ENOG4105ENE	Histidine kinase
BN424_1345	ENOG4105WH1	Two component transcriptional regulator luxr family
BN424_1346	ENOG4107ZYR	domain protein
BN424_1347	ENOG4105W8X	HesB YadR YfhF-family protein
BN424_1349	ENOG4106EHS	UPF0356 protein
BN424_135	ENOG4105C5Y	PTS System
BN424_1353	ENOG4108X4Q	Hydrolase
BN424_1355	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BN424_136	ENOG4105CID	antiterminator
BN424_1360	ENOG41068JE	domain protein
BN424_1362	ENOG4107YB9	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BN424_1363	ENOG4105D82	Glutamate dehydrogenase
BN424_1364	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN424_1367	ENOG4107RUY	(E1 component), alpha subunit
BN424_1370	ENOG4107QN2	dihydrolipoyl dehydrogenase
BN424_1371	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BN424_1372	ENOG4105WBI	UPF0223 protein
BN424_1373	ENOG4105ECY	inositol monophosphatase
BN424_1374	ENOG4105ECY	inositol monophosphatase
BN424_1375	ENOG4108I0Z	Aconitate hydratase
BN424_1376	ENOG4105BZN	citrate synthase
BN424_1377	ENOG4108HMX	isocitrate dehydrogenase (NADP)
BN424_1379	ENOG4105CI3	gtp-binding protein typa
BN424_1380	ENOG4105ZPI	UPF0358 protein
BN424_1381	ENOG4105CNI	cell division protein FtsW
BN424_1382	ENOG4105CNI	cell division protein FtsW
BN424_1383	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
BN424_1384	ENOG4106UY4	Inherit from COG: Scp-like extracellular
BN424_1386	ENOG4105WUC	UPF0298 protein
BN424_1388	ENOG4106H78	methyltransferase
BN424_1389	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BN424_1390	ENOG41063PX	domain protein
BN424_1391	ENOG4105KQC	Competence protein
BN424_1392	ENOG4108UK2	deaminase
BN424_1394	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
BN424_1395	ENOG4108EC8	DNA internalization-related competence protein ComEC
BN424_1396	ENOG4105TQK	DNA polymerase iii, delta' subunit
BN424_1397	ENOG4105TQK	DNA polymerase iii, delta' subunit
BN424_1398	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BN424_1399	ENOG4105II7	pyrroline-5-carboxylate reductase
BN424_1400	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BN424_1404	ENOG4106ETB	IIa component
BN424_1405	ENOG4105H6Q	decarboxylase
BN424_1406	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
BN424_1407	ENOG4105CR5	Class II aldolase adducin family protein
BN424_141	ENOG4108TZY	GntR Family Transcriptional Regulator
BN424_1410	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BN424_1411	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BN424_1412	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BN424_1414	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BN424_1415	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BN424_142	ENOG4105CS2	ec 3.2.1.21
BN424_1423	ENOG4105I8F	Histidine kinase
BN424_143	ENOG4105CK1	PTS System
BN424_1437	ENOG41066F8	ROK family
BN424_1440	ENOG4108MCI	Transcriptional regulator, ARAC family
BN424_1443	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BN424_1447	ENOG4105R40	Glycine betaine carnitine choline
BN424_1452	ENOG4105DSJ	YicC domain protein
BN424_1453	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BN424_1454	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BN424_1455	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BN424_1456	ENOG4105C25	Primosomal protein n'
BN424_1458	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BN424_1459	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BN424_146	ENOG4105EPR	degv family
BN424_1460	ENOG4108ZF3	Phosphatase
BN424_1461	ENOG4105D9P	serine threonine protein kinase
BN424_1462	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BN424_1463	ENOG4105DJV	ribulose-phosphate 3-epimerase
BN424_1464	ENOG4105FJ0	thiamine
BN424_1465	ENOG4105VB9	50S ribosomal protein l28
BN424_1466	ENOG4108ZAA	Alkaline-shock protein
BN424_1467	ENOG4105DP4	dak2 domain fusion protein ylov
BN424_1469	ENOG4105EJQ	L-serine dehydratase
BN424_1470	ENOG4105CB5	ATP-dependent DNA helicase recG
BN424_1471	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BN424_1472	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BN424_1473	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BN424_1474	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BN424_1475	ENOG410667J	hydrolase
BN424_1476	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BN424_1477	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
BN424_1479	ENOG4105K5M	30s ribosomal protein S16
BN424_1480	ENOG4105VB6	UPF0109 protein
BN424_1481	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BN424_1482	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BN424_1483	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BN424_1493	ENOG4105VUF	Transcriptional regulator
BN424_1495	ENOG4105CPC	Aldo Keto reductase
BN424_1496	ENOG4105VUF	Transcriptional regulator
BN424_1497	ENOG4105DQ4	alcohol dehydrogenase
BN424_1498	ENOG4108W5M	transcriptional regulator
BN424_1504	ENOG4108VPT	UPF0234 protein
BN424_1505	ENOG4107AYK	membrAne
BN424_1506	ENOG4108KP7	hydrolase
BN424_1507	ENOG4108MXZ	Esterase
BN424_1508	ENOG4105VG1	fes assembly suf system protein
BN424_1509	ENOG4105C02	permease
BN424_151	ENOG4105D06	uba thif-type nad fad binding protein
BN424_1510	ENOG4107YZX	Universal stress protein
BN424_1512	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BN424_1514	ENOG4105C0B	DNA polymerase III (alpha subunit)
BN424_1515	ENOG4105C0B	DNA polymerase III (alpha subunit)
BN424_1516	ENOG4105CTQ	phosphohexokinase
BN424_1519	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BN424_1521	ENOG4105QNR	S1 RNA binding domain protein
BN424_1522	ENOG4105I3K	Ferric uptake regulator, Fur family
BN424_1524	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
BN424_1526	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BN424_1528	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BN424_1529	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BN424_153	ENOG4105CJ1	ABC, transporter
BN424_1530	ENOG4105FE9	pseudouridine synthase
BN424_1531	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN424_1532	ENOG4105BZU	Histidine kinase
BN424_1533	ENOG4108SAX	Membrane
BN424_1536	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BN424_1537	ENOG41068JE	domain protein
BN424_1538	ENOG4105CAT	Cytidine monophosphate kinase
BN424_1539	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BN424_1540	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BN424_1541	ENOG4105K70	DNA-binding protein
BN424_1542	ENOG4105D49	3-dehydroquinate synthase
BN424_1543	ENOG41068YB	TPR repeat-containing protein
BN424_1544	ENOG4108SXZ	UPF0302 protein
BN424_1545	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
BN424_1546	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BN424_1547	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BN424_1551	ENOG4105E3A	(ABC) transporter
BN424_1552	ENOG4105DA5	(ABC) transporter
BN424_1554	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BN424_1555	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BN424_1558	ENOG4105DBV	ornithine carbamoyltransferase
BN424_1560	ENOG4105DVT	helicase
BN424_1563	ENOG4105C5S	asparaginyl-tRNA synthetase
BN424_1565	ENOG4105CSM	endonuclease III
BN424_1566	ENOG4105BZ4	penicillin-binding protein
BN424_1567	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
BN424_1568	ENOG4108UKS	UPF0398 protein
BN424_1569	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
BN424_157	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
BN424_1570	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BN424_1571	ENOG4105CTD	carboxy-peptidase
BN424_1573	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BN424_1576	ENOG4105VEQ	Cold shock protein
BN424_158	ENOG4105DY9	regulatoR
BN424_1583	ENOG4105C5H	ABC transporter
BN424_1584	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BN424_1586	ENOG4108UT2	hemolysin iii
BN424_1587	ENOG4108RCR	degv family
BN424_1588	ENOG41090WU	lipolytic protein G-D-S-L family
BN424_1590	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BN424_1592	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
BN424_1595	ENOG4105C3F	Signal peptidase i
BN424_1597	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BN424_1598	ENOG4105C79	DNA protecting protein DprA
BN424_1599	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BN424_160	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BN424_1600	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BN424_1601	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN424_1602	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BN424_1603	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BN424_1606	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BN424_1607	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN424_1610	ENOG4105F1A	Pyruvate formate-lyase
BN424_1611	ENOG4105DUM	transcriptional regulator, lysR family
BN424_1613	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
BN424_1614	ENOG4108HRK	Histidine kinase
BN424_1615	ENOG4105DY9	regulatoR
BN424_1617	ENOG41067MG	lrgb family
BN424_1618	ENOG4107QHE	Choloylglycine hydrolase
BN424_163	ENOG4105BZU	Histidine kinase
BN424_1631	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
BN424_1641	ENOG4105CHH	sulfate transporter
BN424_1645	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN424_1646	ENOG4105D6J	arsenicaL-resistance protein
BN424_165	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN424_1650	ENOG4108U05	Transcriptional regulator
BN424_1651	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BN424_1652	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BN424_1659	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
BN424_1661	ENOG4105FH5	Membrane
BN424_1667	ENOG4108RCF	TRANSCRIPTIONal
BN424_1671	ENOG4105E2Y	ABC, transporter
BN424_1672	ENOG4105C7J	ABC transporter, permease
BN424_1675	ENOG4107WZZ	SMC domain protein
BN424_1679	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BN424_168	ENOG4108W15	Protein of unknown function (DUF1456)
BN424_1680	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BN424_1681	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BN424_1682	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BN424_1683	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BN424_1684	ENOG4105DDQ	anthranilate synthase
BN424_1685	ENOG4105CRQ	synthase (Component I)
BN424_1686	ENOG4105CRQ	synthase (Component I)
BN424_1688	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BN424_1689	ENOG4105F23	Fibronectin-binding protein
BN424_1692	ENOG4107VC0	DNA alkylation repair enzyme
BN424_1696	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BN424_1697	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BN424_1700	ENOG4105E0A	ABC, transporter
BN424_1701	ENOG4105EHG	Permease protein
BN424_1702	ENOG4105DQ5	transport system permease protein
BN424_1703	ENOG4105CAY	ferredoxin--nadp reductase
BN424_1705	ENOG4105J76	Periplasmic binding protein
BN424_1710	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BN424_1713	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
BN424_1714	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BN424_1715	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BN424_1716	ENOG4105CD3	dihydroorotase
BN424_1717	ENOG4105CXT	aspartate transcarbamylase
BN424_1719	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BN424_1720	ENOG4105C34	Pseudouridine synthase
BN424_1721	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BN424_1723	ENOG4105C5R	Aminotransferase
BN424_1724	ENOG4105G9B	Transcriptional regulator
BN424_1725	ENOG4105C5B	carbamate kinase
BN424_1728	ENOG4107REC	cytoplasmic protein
BN424_1729	ENOG4107R1Q	Membrane protein FdrA
BN424_173	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BN424_1730	ENOG4105DG4	malate L-lactate dehydrogenase
BN424_1731	ENOG4105DG4	malate L-lactate dehydrogenase
BN424_1732	ENOG4105S0E	allantoin catabolism protein
BN424_1734	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
BN424_1736	ENOG4105DUX	Transporter
BN424_1740	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
BN424_1741	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BN424_1742	ENOG4107UIE	peptidase
BN424_1743	ENOG4107XNU	peptidase
BN424_1746	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BN424_1747	ENOG4105EGD	dinuclear metal center protein, YbgI family
BN424_1749	ENOG4107X35	defense response to bacterium
BN424_1754	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BN424_1755	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BN424_1756	ENOG4105BZ1	(ABC) transporter
BN424_1758	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
BN424_1759	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
BN424_176	ENOG4108MXZ	Esterase
BN424_1760	ENOG4108Z6X	(sortase) family
BN424_1762	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
BN424_1763	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BN424_1765	ENOG4107YR5	Diacylglycerol kinase
BN424_1766	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BN424_1768	ENOG4105C9A	Phoh family
BN424_1771	ENOG4105KTH	gatB Yqey
BN424_1773	ENOG4105N80	Ferric uptake regulator, Fur family
BN424_1775	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BN424_1776	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BN424_1777	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BN424_1778	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BN424_1779	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BN424_1780	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BN424_1781	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BN424_1784	ENOG4108V0P	LemA family
BN424_1786	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BN424_179	ENOG4105CHR	reductase
BN424_1791	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
BN424_1792	ENOG4108DBC	nitroreductase
BN424_1793	ENOG4105VK3	rdd domain containing protein
BN424_1795	ENOG4105C9M	aspartyl-trna synthetase
BN424_1796	ENOG4105CUT	histidyl-tRNA synthetase
BN424_1797	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BN424_1798	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BN424_1799	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BN424_180	ENOG410807C	QueT transporter
BN424_1802	ENOG4108K5P	(LipO)protein
BN424_1803	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BN424_1804	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BN424_1805	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BN424_1807	ENOG4108VX5	3-methyladenine DNA glycosylase
BN424_1809	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
BN424_181	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BN424_1810	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
BN424_1811	ENOG4105ETD	TRANSCRIPTIONal
BN424_182	ENOG4105D01	(LipO)protein
BN424_1826	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN424_1829	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
BN424_1832	ENOG41068G1	
BN424_184	ENOG4105D2N	Aldolase
BN424_1855	ENOG4108C66	Inherit from COG: DNA primase
BN424_188	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BN424_1894	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN424_1895	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BN424_1896	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BN424_1897	ENOG4105CFG	Acts as a chaperone (By similarity)
BN424_1898	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BN424_1899	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BN424_19	ENOG4107RA4	Glycosyl transferase (Group 1
BN424_190	ENOG4105CGH	5'-nucleotidase
BN424_1900	ENOG4108Z4K	mutator MutT protein
BN424_1905	ENOG4105CSA	Coproporphyrinogen iii oxidase
BN424_1906	ENOG4105DTN	riboflavin biosynthesis protein ribF
BN424_1907	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BN424_1908	ENOG4108RCR	degv family
BN424_1909	ENOG4105CBD	Diacylglycerol kinase
BN424_1915	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BN424_1918	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
BN424_1919	ENOG4105CHV	Transcription elongation factor NusA
BN424_1920	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BN424_1922	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BN424_1923	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BN424_1924	ENOG4105DZP	Membrane-associated zinc metalloprotease
BN424_1925	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BN424_1926	ENOG4105KNE	Phosphatidate cytidylyltransferase
BN424_1928	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BN424_193	ENOG4105CK1	PTS System
BN424_1930	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BN424_1931	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BN424_1932	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BN424_1933	ENOG4105CE9	30S ribosomal protein S2
BN424_1935	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BN424_194	ENOG4105CS2	ec 3.2.1.21
BN424_1941	ENOG4105EYH	Exonuclease
BN424_1943	ENOG4107RFY	SbcCD D subunit
BN424_1944	ENOG4105F6E	Acyl-transferase
BN424_1945	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BN424_1946	ENOG4105BZ1	(ABC) transporter
BN424_1947	ENOG4105BZ1	(ABC) transporter
BN424_1948	ENOG4105VXM	UPF0154 protein
BN424_195	ENOG4105VZJ	PTS System
BN424_1951	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BN424_1954	ENOG4106UBQ	
BN424_1956	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BN424_1957	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BN424_1958	ENOG4107YB6	acetyltransferase, (GNAT) family
BN424_196	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
BN424_1960	ENOG41067VP	Protein of unknown function (DUF1049)
BN424_1961	ENOG4108IXY	short-chain dehydrogenase reductase
BN424_1962	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BN424_1964	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BN424_1965	ENOG410901P	UPF0249 protein
BN424_1968	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BN424_197	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
BN424_1970	ENOG4105XTG	Pfam:DUF156
BN424_1971	ENOG4105VFE	sira family
BN424_1972	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN424_1973	ENOG4107YZP	Rhodanese domain protein
BN424_1974	ENOG4105DA5	(ABC) transporter
BN424_1979	ENOG4105MVE	transcriptional regulator
BN424_1980	ENOG4105DE4	1-phosphofructokinase
BN424_1981	ENOG4105DM4	PTS System
BN424_1984	ENOG4105CIG	ABC transporter
BN424_1985	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BN424_1987	ENOG4105CDA	abc transporter atp-binding protein
BN424_1988	ENOG4108HW3	(ABC) transporter
BN424_199	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BN424_1994	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BN424_1995	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BN424_1996	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BN424_2	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BN424_2006	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BN424_2007	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BN424_2009	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BN424_2012	ENOG4105CE1	Ferrous iron transport protein b
BN424_2015	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BN424_2016	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BN424_2017	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BN424_2018	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BN424_2020	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BN424_2021	ENOG4105CHR	reductase
BN424_2022	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BN424_2024	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BN424_2025	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BN424_2028	ENOG4105EFI	regulatoR
BN424_2029	ENOG4105BZU	Histidine kinase
BN424_2030	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
BN424_2031	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BN424_2032	ENOG4105C98	muts2 protein
BN424_2037	ENOG4105C5F	glutamine synthetase
BN424_2038	ENOG4105KV4	Transcriptional regulator
BN424_2039	ENOG4105CXI	aluminum resistance protein
BN424_2040	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BN424_2041	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BN424_2042	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BN424_2044	ENOG4107YZP	Rhodanese domain protein
BN424_2046	ENOG4105DKQ	ROK family
BN424_2047	ENOG4105DKQ	ROK family
BN424_2049	ENOG4107ZXI	Rhomboid family
BN424_2050	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BN424_2051	ENOG4105WDJ	50S ribosomal protein L33
BN424_2055	ENOG4107RF6	penicillin-binding protein
BN424_2056	ENOG4105EJV	Membrane
BN424_2058	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BN424_2063	ENOG4105C1J	atp-dependent rna helicase
BN424_2064	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BN424_2067	ENOG4105SFS	phosphoesterase RecJ domain protein
BN424_2069	ENOG4105E8R	UPF0173 metal-dependent hydrolase
BN424_2070	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BN424_2071	ENOG4105KST	dependent repressor
BN424_2072	ENOG4108EKI	Dehydrogenase
BN424_2074	ENOG4105FF5	Membrane
BN424_2075	ENOG4105VIE	preprotein translocase, subunit YajC
BN424_2076	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BN424_2077	ENOG4105MKU	Transcriptional regulator
BN424_2078	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BN424_2079	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BN424_2080	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BN424_2085	ENOG4105E0X	reductase
BN424_2088	ENOG4108Z03	MAF-like protein
BN424_2089	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BN424_209	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BN424_2090	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BN424_2092	ENOG4105D48	metallophosphoesterase
BN424_2093	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BN424_2097	ENOG4105CEV	competence damage-inducible protein
BN424_2099	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BN424_2100	ENOG4107SUZ	Sodium/hydrogen exchanger family
BN424_2102	ENOG4105CHR	reductase
BN424_2106	ENOG4105UIB	(ABC) transporter
BN424_2107	ENOG4108JQ9	ABC transporter
BN424_2109	ENOG4105DIH	basic membrane
BN424_2110	ENOG4105CNU	cell division protein FtsK
BN424_2112	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BN424_2113	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BN424_2115	ENOG410855V	Acylphosphatase
BN424_2116	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
BN424_2117	ENOG4105GR3	Histidine kinase
BN424_2118	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN424_2120	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
BN424_2144	ENOG4108MDF	Phage Portal Protein
BN424_215	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BN424_216	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BN424_2178	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN424_2179	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BN424_2180	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BN424_2184	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN424_2186	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BN424_2187	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
BN424_2189	ENOG4105DX0	Hemolysin A
BN424_2191	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BN424_2192	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BN424_2193	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BN424_2194	ENOG4105M7K	Involved in the transcription termination process (By similarity)
BN424_2195	ENOG4108ZSR	alkaline shock protein
BN424_2196	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BN424_2197	ENOG4105DC7	peptidase M24
BN424_2205	ENOG4105DUM	transcriptional regulator, lysR family
BN424_2206	ENOG4105HMI	Membrane
BN424_2207	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
BN424_2211	ENOG4105CDY	transcriptional regulatory protein
BN424_2212	ENOG4105NAE	bifunctional deaminase-reductase domain protein
BN424_2216	ENOG4105K4H	Nlp p60 protein
BN424_2217	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BN424_2218	ENOG4105C72	UPF0176 protein
BN424_2219	ENOG4108JJB	ABC transporter
BN424_2220	ENOG4105C7J	ABC transporter, permease
BN424_2224	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_2226	ENOG4105DC7	peptidase M24
BN424_2228	ENOG4105D8X	mechanosensitive ion channel
BN424_2230	ENOG4105CH2	amidohydrolase
BN424_2237	ENOG4108FK2	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BN424_2240	ENOG4105RHA	ABC transporter, permease
BN424_2241	ENOG4108IUX	(ABC) transporter
BN424_2242	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
BN424_2243	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
BN424_2244	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
BN424_2245	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
BN424_2247	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BN424_2253	ENOG4105K63	Thioredoxin
BN424_2254	ENOG4105C98	muts2 protein
BN424_2258	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BN424_2259	ENOG4107R7I	amino acid
BN424_2261	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BN424_2262	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BN424_2268	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BN424_227	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN424_2270	ENOG4105JVQ	RNA Polymerase
BN424_2272	ENOG4108RWN	rrna methyltransferase
BN424_2273	ENOG4105E4C	Lytic transglycosylase catalytic
BN424_2276	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BN424_2277	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BN424_2278	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
BN424_2279	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BN424_2283	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BN424_2285	ENOG4105F8D	glycoside hydrolase family 4
BN424_2288	ENOG4107YZX	Universal stress protein
BN424_2289	ENOG4107YZX	Universal stress protein
BN424_2293	ENOG4108TVJ	Nitroreductase
BN424_2294	ENOG4107DA6	Transcriptional regulator
BN424_2297	ENOG4105CGH	5'-nucleotidase
BN424_2305	ENOG4105E98	transcriptional regulator DeoR family
BN424_2307	ENOG4105D2N	Aldolase
BN424_2308	ENOG4105CK5	oxidoreductase
BN424_2309	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
BN424_2310	ENOG4106448	streptomycin biosynthesis protein strI
BN424_2311	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
BN424_2312	ENOG4105D7K	pfkb domain protein
BN424_2313	ENOG4105DH8	myo-inositol catabolism
BN424_2317	ENOG4108Z6X	(sortase) family
BN424_2318	ENOG4105BZU	Histidine kinase
BN424_2319	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BN424_2325	ENOG4105D9M	gamma-glutamylcysteine synthetase
BN424_2330	ENOG4105Z8B	NlpC/P60 family
BN424_2331	ENOG4108K5P	(LipO)protein
BN424_2333	ENOG4105C59	p-type ATPase
BN424_2336	ENOG4105D13	transposase
BN424_2338	ENOG4107RBB	ABC transporter, permease
BN424_2339	ENOG4105C19	ABC transporter
BN424_2347	ENOG4108IUW	ABC transporter
BN424_236	ENOG4105CS2	ec 3.2.1.21
BN424_2360	ENOG4108K5P	(LipO)protein
BN424_2372	ENOG41090U3	tautomerase
BN424_2373	ENOG4107SDZ	Galactoside transport system permease protein mglC
BN424_2374	ENOG4105C2J	ABC transporter
BN424_2378	ENOG4105BZU	Histidine kinase
BN424_2379	ENOG4108YZA	Nitrogen regulatory protein pii
BN424_238	ENOG4105E03	chitinase
BN424_2381	ENOG4105EQD	regulatoR
BN424_2382	ENOG4105C2F	Histidine kinase
BN424_2385	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN424_2386	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BN424_2387	ENOG4105EB3	Histidine kinase
BN424_2388	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN424_239	ENOG4106ETB	IIa component
BN424_2390	ENOG4108JQ7	(ABC) transporter
BN424_2392	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BN424_2393	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BN424_2395	ENOG4105C31	Tryptophanyl-tRNA synthetase
BN424_2396	ENOG4105DF9	Lipoate-protein, ligase
BN424_2397	ENOG4108RQ5	Beta-lactamase domain-containing protein
BN424_2398	ENOG4105C1Q	protoporphyrinogen oxidase
BN424_2401	ENOG4105CN9	Peptidase m42 family protein
BN424_2404	ENOG4105CAQ	asparagine synthetase
BN424_2406	ENOG4106N3A	copper homeostasis protein cutc
BN424_2407	ENOG4108ZJ4	polysaccharide deacetylase
BN424_2409	ENOG4105E0M	Sulfatase
BN424_2412	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BN424_2413	ENOG4105D6E	homoserine dehydrogenase
BN424_2414	ENOG4107IN1	Protein of unknown function (DUF1797)
BN424_2415	ENOG4105CHM	Aminotransferase
BN424_2416	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BN424_2418	ENOG4105W2C	Glycosyl transferase
BN424_2419	ENOG4105BZF	Glycosyl transferase (Group 1
BN424_2420	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BN424_2421	ENOG4105KRI	phosphocarrier protein (HPr
BN424_2424	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BN424_2428	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BN424_2432	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN424_2433	ENOG4105C02	permease
BN424_2435	ENOG4105DER	m42 family
BN424_2437	ENOG41082BV	acetyltransferase
BN424_2439	ENOG4105CJW	magnesium transporter
BN424_244	ENOG4105E2X	shikimate dehydrogenase
BN424_2440	ENOG4105EMS	pseudouridine synthase
BN424_2443	ENOG4105MIX	Adenylate cyclase
BN424_2445	ENOG4105DPN	Oligoendopeptidase f
BN424_2448	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BN424_2449	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
BN424_245	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
BN424_2451	ENOG4105CAG	UPF0210 protein
BN424_2452	ENOG4105VUC	UPF0237 protein
BN424_2453	ENOG4105K63	Thioredoxin
BN424_2454	ENOG4107SUZ	Sodium/hydrogen exchanger family
BN424_2456	ENOG4108W8B	Beta-lactamase domain protein
BN424_2458	ENOG4105EPR	degv family
BN424_2459	ENOG4105K5B	UPF0225 protein
BN424_246	ENOG4105D49	3-dehydroquinate synthase
BN424_2460	ENOG4105BZF	Glycosyl transferase (Group 1
BN424_2462	ENOG4105EEM	helicase
BN424_2463	ENOG4105EEM	helicase
BN424_247	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BN424_2478	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
BN424_2484	ENOG4105CS2	ec 3.2.1.21
BN424_2485	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
BN424_249	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BN424_2490	ENOG4105D2M	Aldolase
BN424_2491	ENOG4105DE4	1-phosphofructokinase
BN424_2492	ENOG4105CE4	GlcNAc 6-P deacetylase
BN424_2493	ENOG4105F3R	pts system mannose fructose sorbose family iid
BN424_2494	ENOG4105ETZ	PTS System
BN424_2496	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
BN424_2497	ENOG4105E70	isomerase
BN424_2499	ENOG4105FDP	GntR family transcriptional regulator
BN424_250	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BN424_2500	ENOG4105BZW	Glycerate kinase
BN424_2501	ENOG4107EFR	Flavocytochrome c
BN424_2502	ENOG4105C59	p-type ATPase
BN424_2508	ENOG4105DVE	abc transporter atp-binding protein
BN424_251	ENOG4105CQC	Prephenate dehydratase
BN424_2537	ENOG4105CG3	alpha amylase, catalytic region
BN424_2538	ENOG4107URF	beta-phospho-glucomutase
BN424_2539	ENOG4107URF	beta-phospho-glucomutase
BN424_2541	ENOG4108VP7	maltodextrose utilization protein MalA
BN424_2542	ENOG4105EG2	ABC transporter, permease
BN424_2543	ENOG4105D56	permease protein
BN424_2544	ENOG4107FKK	extracellular solute-binding protein family 1
BN424_2545	ENOG4108IUK	alpha amylase, catalytic
BN424_2546	ENOG4105CG3	alpha amylase, catalytic region
BN424_2547	ENOG4105FKQ	transcriptional regulator
BN424_2548	ENOG4105G5W	regulator Fur family
BN424_2549	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BN424_2550	ENOG4107NBY	Membrane
BN424_2552	ENOG4105EVI	UPF0374 protein
BN424_2555	ENOG4105CEN	a g-specific adenine glycosylase
BN424_2556	ENOG410902V	Modulates RecA activity (By similarity)
BN424_2557	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN424_2558	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN424_2559	ENOG4105C02	permease
BN424_256	ENOG4105ETD	TRANSCRIPTIONal
BN424_2563	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BN424_2566	ENOG4105ZMH	deoxynucleoside kinase
BN424_2567	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BN424_2569	ENOG4108KGH	TRANSCRIPTIONal
BN424_257	ENOG4105ETD	TRANSCRIPTIONal
BN424_2572	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BN424_2580	ENOG4107U9T	Pfam:Ribonuclease_BN
BN424_2581	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BN424_2586	ENOG4105C88	aminopeptidase
BN424_2592	ENOG4105VCP	PTS System
BN424_2593	ENOG4105VZJ	PTS System
BN424_2594	ENOG4105VZJ	PTS System
BN424_2595	ENOG4105VZJ	PTS System
BN424_2596	ENOG4105CK1	PTS System
BN424_2597	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BN424_2598	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BN424_2600	ENOG4105EE0	oxidoreductase
BN424_2605	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
BN424_2634	ENOG4108UUM	single-stranded DNA-binding protein
BN424_2638	ENOG4107YVC	modification (methylase)
BN424_266	ENOG4108UW5	maltose o-acetyltransferase
BN424_2665	ENOG4107Y5K	Resolvase
BN424_2666	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN424_2667	ENOG4105CBD	Diacylglycerol kinase
BN424_2668	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BN424_2669	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BN424_2670	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BN424_2672	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BN424_2673	ENOG4105C4R	Atp-dependent dna helicase
BN424_2678	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BN424_2679	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BN424_268	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
BN424_2680	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BN424_2681	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
BN424_2683	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
BN424_2684	ENOG4105C8V	SAICAR synthetase
BN424_2685	ENOG4108UYE	Lactoylglutathione lyase
BN424_2686	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BN424_2689	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BN424_2690	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN424_2691	ENOG4105CP7	Triose-phosphate isomerase
BN424_2693	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BN424_2695	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BN424_2699	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BN424_27	ENOG4105CDU	Replicative dna helicase
BN424_2701	ENOG4105CIE	May be required for sporulation (By similarity)
BN424_2703	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BN424_2705	ENOG4105C3M	thioredoxin reductase
BN424_2707	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BN424_2708	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BN424_2709	ENOG4107XGZ	Hydrolase
BN424_2710	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BN424_2711	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BN424_2712	ENOG41086DT	Membrane protein of unknown function
BN424_2715	ENOG4108PY7	
BN424_2716	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BN424_2717	ENOG4105DK2	UPF0207 protein
BN424_2719	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BN424_272	ENOG4105CEU	Arginine dihydrolase
BN424_2720	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BN424_2721	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BN424_2722	ENOG4105E2Z	phosphate ABC transporter (Permease
BN424_2723	ENOG4105C8U	phosphate abc transporter
BN424_2724	ENOG4105CVA	phosphate
BN424_2725	ENOG4105CVA	phosphate
BN424_2727	ENOG4105BZU	Histidine kinase
BN424_2728	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BN424_273	ENOG4105DBV	ornithine carbamoyltransferase
BN424_2731	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BN424_2732	ENOG4105CAK	Cell division ATP-binding protein ftsE
BN424_2733	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BN424_2734	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BN424_2739	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BN424_274	ENOG4105DBV	ornithine carbamoyltransferase
BN424_2740	ENOG4108KGH	TRANSCRIPTIONal
BN424_2741	ENOG4105ESV	Glycosyl transferase, family 4
BN424_2743	ENOG4105FDP	GntR family transcriptional regulator
BN424_2744	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BN424_2745	ENOG4105CE4	GlcNAc 6-P deacetylase
BN424_2748	ENOG4107T7U	Sulfatase
BN424_2749	ENOG4105CKK	Glycosyl transferase, family 2
BN424_2750	ENOG4105WH5	Teichoic acid glycosylation protein
BN424_2751	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
BN424_2752	ENOG4105DAP	Nicotinate phosphoribosyltransferase
BN424_2755	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BN424_2757	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BN424_2758	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
BN424_276	ENOG4105C5B	carbamate kinase
BN424_2764	ENOG4105HTX	biosynthesis protein
BN424_2766	ENOG4107T7U	Sulfatase
BN424_2767	ENOG4107X35	defense response to bacterium
BN424_2768	ENOG4105CMR	udp-glucose 4-epimerase
BN424_2770	ENOG4107QHE	Choloylglycine hydrolase
BN424_2771	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BN424_2772	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BN424_2773	ENOG4108TYN	CAAX amino terminal protease family protein
BN424_2775	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
BN424_2776	ENOG4105C5H	ABC transporter
BN424_2777	ENOG4108KGH	TRANSCRIPTIONal
BN424_2778	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BN424_2781	ENOG41072GX	Peptidase M22 Glycoprotease
BN424_2789	ENOG4108Z6X	(sortase) family
BN424_2798	ENOG4108F3G	Type I restriction-modification system, R subunit
BN424_2799	ENOG4105M6F	mutator MutT protein
BN424_28	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BN424_280	ENOG4108M1A	Chitin-binding protein
BN424_2800	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN424_2806	ENOG4105KY5	gCN5-related N-acetyltransferase
BN424_2809	ENOG4108XI2	Domain of unknown function (DUF1963)
BN424_281	ENOG4105CVJ	phosphoglycerate mutase
BN424_2811	ENOG4105C5X	domain protein
BN424_2815	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
BN424_2817	ENOG4105UIB	(ABC) transporter
BN424_2818	ENOG4108JQ9	ABC transporter
BN424_2819	ENOG4105DIH	basic membrane
BN424_282	ENOG4105C5Q	Transcriptional regulator
BN424_2822	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BN424_2823	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
BN424_2824	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_2825	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_2828	ENOG4105FS7	Transcriptional regulator
BN424_283	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN424_2832	ENOG4108URH	decarboxylase
BN424_2833	ENOG4105DC8	reductase
BN424_2835	ENOG4105UNS	Pfam:DUF419
BN424_2837	ENOG4105D29	Helix-turn-helix type 11 domain protein
BN424_2840	ENOG4105CPF	Cell wall formation (By similarity)
BN424_2841	ENOG4108ZJ4	polysaccharide deacetylase
BN424_2845	ENOG41082DI	50s ribosomal protein l31
BN424_2846	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BN424_2847	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BN424_2848	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BN424_2849	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
BN424_285	ENOG4105D98	threonine synthase
BN424_2851	ENOG4105DKT	Transcriptional regulator
BN424_2854	ENOG4107RUY	(E1 component), alpha subunit
BN424_2855	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
BN424_2856	ENOG4105DCI	Phosphohydrolase
BN424_2857	ENOG410667J	hydrolase
BN424_2858	ENOG41069HH	4-oxalocrotonate tautomerase
BN424_2859	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BN424_2862	ENOG4107QSE	Dipeptidase
BN424_2864	ENOG4105CK1	PTS System
BN424_2865	ENOG4105VZJ	PTS System
BN424_2866	ENOG4105FDP	GntR family transcriptional regulator
BN424_2872	ENOG4105DFD	Na H antiporter
BN424_2873	ENOG4105DY8	decarboxylase
BN424_2874	ENOG4105E5D	amino acid
BN424_2876	ENOG4105X71	Membrane
BN424_2877	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BN424_2878	ENOG4108UMI	ABC transporter, permease
BN424_2879	ENOG4105D01	(LipO)protein
BN424_2880	ENOG4108Z5K	methylglyoxal synthase
BN424_2881	ENOG4105EMV	Major Facilitator
BN424_2882	ENOG4105EMV	Major Facilitator
BN424_2883	ENOG4105FF2	Type I DHQase
BN424_2884	ENOG4105EMV	Major Facilitator
BN424_2887	ENOG4105C5Q	Transcriptional regulator
BN424_2891	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
BN424_2892	ENOG4105CNN	ABC, transporter
BN424_2894	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
BN424_2895	ENOG4108RVA	ribokinase
BN424_2896	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_29	ENOG4108MRH	transcriptional regulatory protein
BN424_2909	ENOG4107QHE	Choloylglycine hydrolase
BN424_2910	ENOG4105CU9	asparagine synthetase A
BN424_2913	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BN424_2918	ENOG4105NAE	bifunctional deaminase-reductase domain protein
BN424_2923	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BN424_2924	ENOG4105CS9	pantothenic acid kinase
BN424_2925	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BN424_2928	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
BN424_293	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BN424_2932	ENOG4108S4H	thioesterase Superfamily protein
BN424_2945	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN424_2947	ENOG4105TMB	Formate nitrite transporter
BN424_295	ENOG4108IJ9	(ABC) transporter
BN424_2957	ENOG4105C02	permease
BN424_2972	ENOG4105C5Y	PTS System
BN424_2973	ENOG4105CID	antiterminator
BN424_2975	ENOG4108V4B	ThiJ pfpI
BN424_2978	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BN424_2982	ENOG4105C19	ABC transporter
BN424_2989	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BN424_299	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
BN424_2990	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BN424_2994	ENOG4105US7	Histidine kinase
BN424_2995	ENOG4108STX	response regulator
BN424_2999	ENOG41069H0	dihydroorotase EC 3.5.2.3
BN424_3	ENOG410848D	S4 domain protein YaaA
BN424_300	ENOG4108HW3	(ABC) transporter
BN424_3002	ENOG4105CK1	PTS System
BN424_301	ENOG4105E5Q	amino acid AbC transporter
BN424_3010	ENOG4105FDP	GntR family transcriptional regulator
BN424_3012	ENOG4105CS2	ec 3.2.1.21
BN424_3013	ENOG4105CK1	PTS System
BN424_3015	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN424_3020	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BN424_3022	ENOG41066F8	ROK family
BN424_3024	ENOG4105C8I	hydrolase, family 38
BN424_3030	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
BN424_3031	ENOG4108S3Y	transcriptional regulator
BN424_3032	ENOG4105CS2	ec 3.2.1.21
BN424_3033	ENOG4105CK1	PTS System
BN424_3034	ENOG4107VFR	oxidoreductase
BN424_3037	ENOG4105CJ1	ABC, transporter
BN424_3051	ENOG4105KFN	sortase, SrtB family
BN424_3054	ENOG4106ST0	Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity)
BN424_3055	ENOG4105SGM	Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity)
BN424_3058	ENOG4108IAJ	Nad-dependent epimerase dehydratase
BN424_3059	ENOG4107QQG	Dehydrogenase
BN424_3061	ENOG4105BZF	Glycosyl transferase (Group 1
BN424_3062	ENOG4105D3Q	Sugar transferase
BN424_3066	ENOG4105D75	Capsular exopolysaccharide family
BN424_3073	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BN424_3076	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BN424_3078	ENOG4107RGD	Major Facilitator superfamily
BN424_3090	ENOG4108V5C	ABC transporter
BN424_3091	ENOG4105EHG	Permease protein
BN424_3092	ENOG4105DQ5	transport system permease protein
BN424_3093	ENOG4105E0A	ABC, transporter
BN424_3094	ENOG4105KWG	Pfam:DUF1696
BN424_3097	ENOG4105F1N	DNA alkylation repair
BN424_3098	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN424_3099	ENOG4105DTQ	mandelate racemase muconate lactonizing
BN424_3100	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
BN424_3101	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
BN424_3102	ENOG4105E4F	Isochorismate synthase
BN424_3104	ENOG4105C8I	hydrolase, family 38
BN424_3105	ENOG4105DM4	PTS System
BN424_3106	ENOG4108YRF	PTS System
BN424_3107	ENOG4105DM4	PTS System
BN424_3109	ENOG4105CK1	PTS System
BN424_3110	ENOG4105HTX	biosynthesis protein
BN424_3111	ENOG4108QV3	biosynthesis protein
BN424_3112	ENOG4105CK1	PTS System
BN424_3113	ENOG4105VZJ	PTS System
BN424_3114	ENOG4105VCP	PTS System
BN424_3116	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BN424_3117	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
BN424_3118	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BN424_3119	ENOG4108IJG	ABC transporter substrate-binding protein
BN424_3121	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BN424_3122	ENOG4108IJ9	(ABC) transporter
BN424_3123	ENOG4105IE8	Alpha-ketoglutarate permease
BN424_3124	ENOG4105C8I	hydrolase, family 38
BN424_3125	ENOG4105DM4	PTS System
BN424_3126	ENOG4108YRF	PTS System
BN424_3127	ENOG4105DM4	PTS System
BN424_3128	ENOG4105ETD	TRANSCRIPTIONal
BN424_3129	ENOG4105F8D	glycoside hydrolase family 4
BN424_3130	ENOG4108RCM	Nitroreductase
BN424_3131	ENOG4105KVH	Transcriptional regulator
BN424_3132	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BN424_3133	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BN424_3135	ENOG4108MK9	spermidine N(1)-acetyltransferase
BN424_3136	ENOG4105K8N	protein family UPF0079, ATPase
BN424_3139	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BN424_3140	ENOG4105VC4	domain protein
BN424_3141	ENOG41060K3	Methyltransferase
BN424_3143	ENOG4105DKW	ABC transporter
BN424_315	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
BN424_3150	ENOG4105UNS	Pfam:DUF419
BN424_3156	ENOG4105M2Z	protein tyrosine serine phosphatase
BN424_3160	ENOG4107RWR	Sodium hydrogen exchanger
BN424_3162	ENOG4108M1A	Chitin-binding protein
BN424_3168	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BN424_3170	ENOG4105BZU	Histidine kinase
BN424_3176	ENOG4108X4Q	Hydrolase
BN424_3179	ENOG4105CHU	acetyl-coa acetyltransferase
BN424_318	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BN424_3180	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
BN424_3181	ENOG4105BZU	Histidine kinase
BN424_3182	ENOG4105BZU	Histidine kinase
BN424_3185	ENOG4107R8N	Glycosyl transferase, family 2
BN424_3191	ENOG4105CK1	PTS System
BN424_3192	ENOG4105DSE	periplasmic solute binding protein
BN424_3193	ENOG4105DIK	(ABC) transporter
BN424_3197	ENOG4105I3N	Conserved Protein
BN424_3198	ENOG4105CK1	PTS System
BN424_3199	ENOG4105VZJ	PTS System
BN424_3201	ENOG4105D4A	Cell wall formation (By similarity)
BN424_3203	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN424_3204	ENOG4105BZU	Histidine kinase
BN424_3205	ENOG4105EP9	oxidoreductase
BN424_3206	ENOG4105CGK	Exodeoxyribonuclease III
BN424_3207	ENOG4107Y2X	deaminase
BN424_3208	ENOG4105W42	Veg protein
BN424_3209	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BN424_3211	ENOG4105F8V	Hydrolase, tatD family
BN424_3212	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BN424_3213	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BN424_3214	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BN424_3215	ENOG4105CEY	Amp-dependent synthetase and ligase
BN424_3216	ENOG4108IPT	Naphthoate synthase
BN424_3217	ENOG4105KA0	thioesterase Superfamily protein
BN424_3218	ENOG4107YZX	Universal stress protein
BN424_3228	ENOG4105VKD	bioY protein
BN424_3232	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN424_3233	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
BN424_3236	ENOG4105DQF	Hydrolase
BN424_3237	ENOG4105CCI	Myosin-Cross-Reactive Antigen
BN424_3239	ENOG4105CDY	transcriptional regulatory protein
BN424_3242	ENOG4108RYK	Nad-dependent epimerase dehydratase
BN424_3243	ENOG4108Z40	Transcriptional regulator
BN424_3244	ENOG4105DZP	Membrane-associated zinc metalloprotease
BN424_3245	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
BN424_3246	ENOG4105CS2	ec 3.2.1.21
BN424_3247	ENOG4105VCP	PTS System
BN424_3248	ENOG4105CK1	PTS System
BN424_3251	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
BN424_3252	ENOG4105MA4	psp1 domain protein
BN424_3253	ENOG4105FA2	dna polymerase iii
BN424_3254	ENOG4105X0R	protein from nitrogen regulatory protein P-II
BN424_3255	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BN424_3261	ENOG4105CXN	decarboxylase
BN424_3263	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BN424_3264	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BN424_3265	ENOG4105C6E	dna polymerase iii
BN424_3272	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BN424_3276	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BN424_3335	ENOG4105II7	pyrroline-5-carboxylate reductase
BN424_3336	ENOG4108Z6B	deaminase
BN424_3339	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BN424_334	ENOG4105BZU	Histidine kinase
BN424_3340	ENOG4105KEX	transcriptional regulator, ctsr
BN424_3360	ENOG4105CK1	PTS System
BN424_3361	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BN424_3362	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BN424_3363	ENOG4105MTF	NrdI protein
BN424_3369	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BN424_337	ENOG4105C37	(CBS) domain
BN424_3370	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BN424_3372	ENOG4107QRS	glycosyltransferase group 2 family protein
BN424_3373	ENOG4105D5D	udp-galactopyranose mutase
BN424_3378	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
BN424_338	ENOG4105D03	DNA-3-methyladenine glycosylase II
BN424_3392	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
BN424_3401	ENOG4108UJD	30S ribosomal protein S9
BN424_3402	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BN424_3404	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BN424_3406	ENOG4108JJB	ABC transporter
BN424_3407	ENOG4108JJB	ABC transporter
BN424_3408	ENOG4105CH2	amidohydrolase
BN424_341	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BN424_3411	ENOG4108ZT0	50S ribosomal protein l17
BN424_3412	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN424_3413	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BN424_3414	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BN424_3416	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BN424_3417	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BN424_3418	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BN424_3419	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BN424_342	ENOG4105XYU	peptidase (U32 family)
BN424_3420	ENOG4105VPB	50S ribosomal protein L30
BN424_3421	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BN424_3422	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BN424_3423	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BN424_3424	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BN424_3425	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BN424_3426	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BN424_3429	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BN424_343	ENOG4105CFP	Peptidase U32
BN424_3430	ENOG41082SA	50s ribosomal protein l29
BN424_3431	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BN424_3432	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BN424_3433	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BN424_3434	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BN424_3435	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BN424_3436	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BN424_3437	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BN424_3438	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BN424_3439	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BN424_344	ENOG4107QHE	Choloylglycine hydrolase
BN424_3440	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BN424_3442	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BN424_3443	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BN424_3444	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BN424_3445	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BN424_3446	ENOG4106A3R	peptidase
BN424_3447	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN424_3448	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN424_345	ENOG4105CVK	Glutamate decarboxylase
BN424_3450	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
BN424_3455	ENOG4107Y49	methyltransferase
BN424_3457	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
BN424_3458	ENOG4105CV8	reductase
BN424_3459	ENOG4105KVH	Transcriptional regulator
BN424_3462	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BN424_3463	ENOG4108VZM	50s ribosomal protein L10
BN424_3464	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BN424_3465	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BN424_3467	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BN424_3468	ENOG410683Z	Preprotein translocase SecE subunit
BN424_3469	ENOG4107FTN	50S ribosomal protein L33
BN424_347	ENOG4105E5D	amino acid
BN424_3472	ENOG41088B0	Major membrane immunogen
BN424_3476	ENOG4105EAH	synthase
BN424_3481	ENOG4105M0M	Tetracycline resistance protein
BN424_3482	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BN424_3483	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BN424_3484	ENOG4105C8N	cysteinyl-tRNA synthetase
BN424_3485	ENOG4105D7W	serine acetyltransferase
BN424_3486	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BN424_3488	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BN424_3489	ENOG4105CTP	PilT protein domain protein
BN424_349	ENOG4107QHE	Choloylglycine hydrolase
BN424_3490	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BN424_3492	ENOG4108V06	Glutathione peroxidase
BN424_3493	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BN424_3494	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
BN424_3495	ENOG4108RZE	Tetr family transcriptional regulator
BN424_3496	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BN424_3497	ENOG4105CPN	adenine deaminase
BN424_3499	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BN424_350	ENOG4105ECB	domain protein
BN424_3501	ENOG4105F38	ABC transporter, permease
BN424_3502	ENOG4105BZU	Histidine kinase
BN424_3503	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN424_3504	ENOG4107RBB	ABC transporter, permease
BN424_3505	ENOG4105C19	ABC transporter
BN424_3509	ENOG4107Y03	Nitroreductase
BN424_3510	ENOG4105C5Y	PTS System
BN424_3511	ENOG4105CS2	ec 3.2.1.21
BN424_3512	ENOG4108UW5	maltose o-acetyltransferase
BN424_3514	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
BN424_3517	ENOG4105C3G	gtp-binding protein
BN424_3518	ENOG4105VDK	protein, conserved in bacteria
BN424_3519	ENOG4105FA0	parb-like partition protein
BN424_352	ENOG4106F5Q	Membrane
BN424_3520	ENOG4107QJE	Chromosome Partitioning Protein
BN424_3521	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
BN424_3522	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BN424_3523	ENOG410756H	nucleotidyltransferase
BN424_3524	ENOG4105DJ2	Major Facilitator Superfamily
BN424_3525	ENOG4105FDP	GntR family transcriptional regulator
BN424_3529	ENOG4105CGH	5'-nucleotidase
BN424_353	ENOG4105EUF	amidase EC 3.5.1.4
BN424_3534	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN424_3535	ENOG4106FN3	tellurium resistance protein
BN424_3536	ENOG4106FN3	tellurium resistance protein
BN424_3537	ENOG4108N0M	stress protein
BN424_3538	ENOG4108TTB	tellurium resistance protein
BN424_3548	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
BN424_3549	ENOG4108ZMX	Domain of unknown function (DU1801)
BN424_3562	ENOG4108C33	Resolvase
BN424_3565	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BN424_3567	ENOG4105M4P	Tetr family transcriptional regulator
BN424_3568	ENOG4107R3K	hydrolase
BN424_3569	ENOG4105E0S	extracellular solute-binding protein family 1
BN424_357	ENOG4108UMN	azlc family
BN424_3570	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN424_3573	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_3576	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BN424_3577	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BN424_3588	ENOG4105DEN	Luciferase family
BN424_3593	ENOG4107414	GntR family transcriptional regulator
BN424_3595	ENOG4105CCI	Myosin-Cross-Reactive Antigen
BN424_3596	ENOG4105CVK	Glutamate decarboxylase
BN424_3597	ENOG4105ECB	domain protein
BN424_3598	ENOG4105E5D	amino acid
BN424_3599	ENOG4107QHE	Choloylglycine hydrolase
BN424_36	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BN424_360	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BN424_3600	ENOG4105C7B	Threonine dehydratase
BN424_3601	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BN424_3602	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BN424_3603	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BN424_3604	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BN424_3605	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BN424_3606	ENOG4108ZP8	Acetolactate synthase small subunit
BN424_3607	ENOG4105C7K	acetolactate synthase
BN424_3608	ENOG4105C01	Dihydroxy-acid dehydratase
BN424_3611	ENOG4105CG3	alpha amylase, catalytic region
BN424_3612	ENOG4105C5Y	PTS System
BN424_3617	ENOG4105CEY	Amp-dependent synthetase and ligase
BN424_3622	ENOG4108IUX	(ABC) transporter
BN424_3626	ENOG4105CMT	Dihydroxyacetone kinase
BN424_3629	ENOG4105VDH	Dihydroxyacetone kinase
BN424_363	ENOG4105C87	Aminotransferase class I and II
BN424_3630	ENOG4108UTZ	Dihydroxyacetone kinase
BN424_3631	ENOG4105CMT	Dihydroxyacetone kinase
BN424_3635	ENOG4108MEK	Metal-binding protein YodA
BN424_3636	ENOG4107XGZ	Hydrolase
BN424_3637	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
BN424_364	ENOG4105CI1	PTS System
BN424_365	ENOG4106KNT	transcriptional regulator
BN424_3654	ENOG4105D74	hydrolase
BN424_3657	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BN424_3659	ENOG4105VG0	50S ribosomal protein l34
BN424_369	ENOG4107ZXU	DSBA oxidoreductase
BN424_371	ENOG4105DP4	dak2 domain fusion protein ylov
BN424_374	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BN424_381	ENOG4108V7D	UPF0397 protein
BN424_382	ENOG4108JJB	ABC transporter
BN424_384	ENOG41081I9	integral membrane protein
BN424_385	ENOG4105T58	Dithiol-disulfide isomerase
BN424_386	ENOG4105EEQ	Na H antiporter
BN424_388	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BN424_389	ENOG4105F38	ABC transporter, permease
BN424_390	ENOG4108I5D	sulfate abc transporter
BN424_393	ENOG4105FR1	rard protein
BN424_394	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BN424_395	ENOG4105CE4	GlcNAc 6-P deacetylase
BN424_398	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
BN424_4	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BN424_404	ENOG4105E5Q	amino acid AbC transporter
BN424_405	ENOG4105CDA	abc transporter atp-binding protein
BN424_406	ENOG4105DSE	periplasmic solute binding protein
BN424_407	ENOG4105FDK	ABC transporter
BN424_409	ENOG4105DFT	pur operon repressor
BN424_413	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BN424_414	ENOG4105DRS	transport system, permease
BN424_415	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BN424_416	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
BN424_417	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_418	ENOG4107UWA	esterase
BN424_419	ENOG4108M1A	Chitin-binding protein
BN424_42	ENOG4108MRH	transcriptional regulatory protein
BN424_429	ENOG4105KTW	ethanolamine utilization protein
BN424_430	ENOG4108WBT	adenosyltransferase
BN424_433	ENOG4105M3W	utilization protein
BN424_436	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
BN424_437	ENOG4105CPD	ethanolamine ammonia-lyase
BN424_438	ENOG4107FQ9	ethanolamine ammonia-lyase
BN424_439	ENOG4106D67	ethanolamine utilization protein
BN424_44	ENOG4105C5I	Dehydrogenase
BN424_441	ENOG4108EKI	Dehydrogenase
BN424_442	ENOG4105KNY	Microcompartments protein
BN424_444	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
BN424_447	ENOG4105ENY	Ethanolamine utilization protein eutH
BN424_448	ENOG4105NDK	ethanolamine utilization protein
BN424_450	ENOG4105D9R	oxidoreductase
BN424_451	ENOG4107XVH	Transcriptional regulator
BN424_452	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BN424_453	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BN424_456	ENOG4107QSE	Dipeptidase
BN424_458	ENOG4106P55	Transcriptional regulator
BN424_46	ENOG4108Z7F	N-acetyltransferase
BN424_460	ENOG4105DZC	cytosine deaminase
BN424_462	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BN424_463	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BN424_464	ENOG4108JA2	transcriptioN-repair coupling factor
BN424_466	ENOG4108IY2	MazG family
BN424_467	ENOG41082I2	s4 domain protein
BN424_469	ENOG41060GV	RNA binding s1 domain protein
BN424_47	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BN424_470	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BN424_471	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BN424_473	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BN424_474	ENOG4105C6T	cysteine synthase
BN424_475	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BN424_476	ENOG4105CRK	lysyL-tRNA synthetase
BN424_48	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN424_488	ENOG4107R4J	Chloride channel
BN424_489	ENOG410874W	AraC family transcriptional regulator
BN424_490	ENOG4105BZ1	(ABC) transporter
BN424_491	ENOG4105BZ1	(ABC) transporter
BN424_496	ENOG4107RA9	decarboxylase
BN424_5	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN424_50	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BN424_504	ENOG4105HDK	L-asparaginase
BN424_505	ENOG4105CVG	Homoserine O-transsuccinylase
BN424_508	ENOG4105C1J	atp-dependent rna helicase
BN424_509	ENOG4105C5H	ABC transporter
BN424_51	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BN424_511	ENOG4105CGH	5'-nucleotidase
BN424_515	ENOG4105C4Y	ABC transporter
BN424_516	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BN424_517	ENOG4107RCV	ABC transporter, permease
BN424_518	ENOG4105C2F	Histidine kinase
BN424_520	ENOG4105E5D	amino acid
BN424_521	ENOG4105C5I	Dehydrogenase
BN424_522	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
BN424_523	ENOG4105E5Q	amino acid AbC transporter
BN424_524	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_525	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
BN424_526	ENOG4107TXC	Transcriptional regulator
BN424_527	ENOG4108YYH	Nadph-dependent fmn reductase
BN424_531	ENOG4105BZ1	(ABC) transporter
BN424_535	ENOG41069ER	domain protein
BN424_537	ENOG4105DCF	alanine dehydrogenase
BN424_538	ENOG4105CS2	ec 3.2.1.21
BN424_54	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BN424_540	ENOG4105EQN	UPF0261 protein
BN424_543	ENOG4105ETE	Transcriptional regulator (LacI family
BN424_544	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BN424_546	ENOG4105CDA	abc transporter atp-binding protein
BN424_547	ENOG4105E5Q	amino acid AbC transporter
BN424_55	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
BN424_551	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BN424_552	ENOG4105DWF	phosphomethylpyrimidine kinase
BN424_553	ENOG4105J7I	hydrolase
BN424_554	ENOG4105EMF	GntR family transcriptional regulator
BN424_556	ENOG4105CMG	Carbohydrate kinase
BN424_557	ENOG4105C6Z	Gluconate
BN424_558	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BN424_559	ENOG4108IJ2	phosphate acetyltransferase
BN424_564	ENOG4105E66	phosphoriboisomerase A
BN424_57	ENOG4105C28	cystathionine
BN424_570	ENOG4105DSE	periplasmic solute binding protein
BN424_571	ENOG4105WDJ	50S ribosomal protein L33
BN424_572	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BN424_575	ENOG4105DQR	SNARE associated Golgi
BN424_577	ENOG4108Z6X	(sortase) family
BN424_579	ENOG4105HUF	DNA protection during starvation protein
BN424_580	ENOG4108V0P	LemA family
BN424_581	ENOG4105D0M	Protease HtpX homolog
BN424_583	ENOG4105KPY	Small multidrug resistance protein
BN424_584	ENOG4105KPY	Small multidrug resistance protein
BN424_587	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
BN424_588	ENOG4105HFZ	Membrane
BN424_589	ENOG4105C1J	atp-dependent rna helicase
BN424_590	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BN424_591	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BN424_595	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
BN424_596	ENOG410807C	QueT transporter
BN424_598	ENOG4108VQJ	O-methyltransferase
BN424_608	ENOG410830R	acetyltransferase
BN424_609	ENOG4105C0X	amino acid
BN424_61	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
BN424_614	ENOG4105CS2	ec 3.2.1.21
BN424_615	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BN424_623	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BN424_624	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BN424_626	ENOG4105BZU	Histidine kinase
BN424_628	ENOG4105FDK	ABC transporter
BN424_63	ENOG4105DQ4	alcohol dehydrogenase
BN424_630	ENOG4107RBB	ABC transporter, permease
BN424_631	ENOG4105C19	ABC transporter
BN424_632	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
BN424_637	ENOG410906U	SprT-like
BN424_639	ENOG4105C3F	Signal peptidase i
BN424_64	ENOG4105C5Y	PTS System
BN424_641	ENOG4105F32	YngK protein
BN424_642	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BN424_644	ENOG4105CK1	PTS System
BN424_646	ENOG4105RD7	BadF BadG BcrA BcrD
BN424_649	ENOG4105VCP	PTS System
BN424_654	ENOG4105EGI	Transcriptional regulator
BN424_656	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
BN424_657	ENOG4105BZ1	(ABC) transporter
BN424_658	ENOG4105BZ1	(ABC) transporter
BN424_660	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BN424_661	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BN424_663	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BN424_664	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
BN424_665	ENOG4105C08	Histidine kinase
BN424_666	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BN424_668	ENOG4108A04	Beta-lactamase
BN424_67	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN424_670	ENOG4105ECB	domain protein
BN424_673	ENOG4105DXB	Major Facilitator superfamily
BN424_675	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
BN424_680	ENOG4105CFH	Aspartokinase
BN424_686	ENOG4105C59	p-type ATPase
BN424_688	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BN424_689	ENOG4105C5Y	PTS System
BN424_690	ENOG4105CVK	Glutamate decarboxylase
BN424_691	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BN424_692	ENOG4105HMI	Membrane
BN424_694	ENOG4105C22	threonyL-tRNA synthetase
BN424_695	ENOG4105C22	threonyL-tRNA synthetase
BN424_696	ENOG4105C22	threonyL-tRNA synthetase
BN424_699	ENOG4105CF7	AraC family transcriptional regulator
BN424_7	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BN424_700	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BN424_701	ENOG4108W0I	acetyltransferase
BN424_705	ENOG4105D9R	oxidoreductase
BN424_71	ENOG4105Q2H	domain protein
BN424_714	ENOG41066F8	ROK family
BN424_715	ENOG4105NYY	transcriptional regulator, RpiR
BN424_716	ENOG4108QVC	Component IIC
BN424_717	ENOG4105CS2	ec 3.2.1.21
BN424_718	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
BN424_72	ENOG4105C0H	protease
BN424_720	ENOG4105D9R	oxidoreductase
BN424_721	ENOG4105CI1	PTS System
BN424_722	ENOG4105F8D	glycoside hydrolase family 4
BN424_723	ENOG4108Q3X	Transcriptional regulator
BN424_725	ENOG4105CI1	PTS System
BN424_731	ENOG4105DFD	Na H antiporter
BN424_732	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BN424_733	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BN424_735	ENOG4105E0M	Sulfatase
BN424_736	ENOG4105DEU	major facilitator superfamily
BN424_737	ENOG4105E0Y	RtcB Protein
BN424_738	ENOG4108TVJ	Nitroreductase
BN424_74	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BN424_744	ENOG4108WCX	response regulator
BN424_749	ENOG410839T	multidrug resistance protein
BN424_750	ENOG41080TC	multidrug resistance protein
BN424_751	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BN424_752	ENOG4105BZ1	(ABC) transporter
BN424_754	ENOG4105BZU	Histidine kinase
BN424_755	ENOG4107XC4	flavin reductase domain protein, FMN-binding
BN424_756	ENOG4105FBA	Phospholipase Carboxylesterase
BN424_759	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
BN424_760	ENOG4107RZX	Teichoic acid biosynthesis protein
BN424_764	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BN424_767	ENOG4105BZ1	(ABC) transporter
BN424_769	ENOG4105PQ4	(LipO)protein
BN424_770	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
BN424_771	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BN424_772	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BN424_776	ENOG4105DG6	mannose-6-phosphate isomerase
BN424_778	ENOG4105F1K	Glutamine amidotransferase
BN424_779	ENOG4105DMS	mur ligase
BN424_781	ENOG4107104	thymidine kinase
BN424_782	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BN424_783	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BN424_784	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BN424_785	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BN424_786	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BN424_787	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
BN424_789	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
BN424_791	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BN424_792	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BN424_794	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BN424_795	ENOG4106778	Protein of unknown function (DUF1146)
BN424_797	ENOG4105DFF	Rod shape-determining protein mreb
BN424_799	ENOG4108UUM	single-stranded DNA-binding protein
BN424_8	ENOG4108UUM	single-stranded DNA-binding protein
BN424_800	ENOG41069ER	domain protein
BN424_801	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN424_802	ENOG4105BZU	Histidine kinase
BN424_805	ENOG4105E0M	Sulfatase
BN424_807	ENOG4105C6X	Major Facilitator
BN424_808	ENOG4105DR4	Methyltransferase
BN424_809	ENOG4107WD8	ABC transporter, permease
BN424_811	ENOG4105D2M	Aldolase
BN424_812	ENOG4108Z66	YbaK ebsC protein
BN424_815	ENOG4105CBX	hi0933 family
BN424_816	ENOG4105CSC	Glucose uptake protein
BN424_817	ENOG4105CUB	amino acid
BN424_820	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BN424_821	ENOG4107RBB	ABC transporter, permease
BN424_822	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BN424_824	ENOG4105DZ6	Band 7 protein
BN424_827	ENOG4108QEG	Membrane
BN424_828	ENOG4105CP9	extracellular ligand-binding receptor
BN424_829	ENOG4105C32	Amino acid ABC transporter (Permease)
BN424_830	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BN424_831	ENOG4105C0Z	ABC transporter
BN424_832	ENOG4108IV0	ABC, transporter
BN424_838	ENOG4106F5Q	Membrane
BN424_840	ENOG4108VXD	carboxy-peptidase
BN424_842	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BN424_844	ENOG4107RVG	penicillin-binding protein
BN424_846	ENOG4108TZY	GntR Family Transcriptional Regulator
BN424_847	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
BN424_848	ENOG4105C2W	permease
BN424_851	ENOG4108U5N	UPF0316 protein
BN424_852	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BN424_853	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BN424_854	ENOG4105C83	adenylosuccinate lyase
BN424_855	ENOG4105CK2	sodium dicarboxylate symporter
BN424_856	ENOG4108JUA	Transcriptional regulator
BN424_857	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
BN424_858	ENOG4105FCD	Major Facilitator
BN424_859	ENOG4105EA8	2-Nitropropane dioxygenase
BN424_861	ENOG4105C84	Histidine ammonia-lyase
BN424_866	ENOG4105NX3	Membrane
BN424_869	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BN424_870	ENOG4108JQ1	Dehydrogenase
BN424_873	ENOG4105XZU	Preprotein translocase, subunit SecG
BN424_875	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BN424_877	ENOG4105CS2	ec 3.2.1.21
BN424_879	ENOG4108VAC	response regulator
BN424_881	ENOG4105CNI	cell division protein FtsW
BN424_888	ENOG4108TZY	GntR Family Transcriptional Regulator
BN424_890	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
BN424_893	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BN424_894	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BN424_895	ENOG4108JJ9	ABC, transporter
BN424_896	ENOG4108JJ8	(ABC) transporter
BN424_898	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BN424_9	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BN424_905	ENOG4105EAH	synthase
BN424_908	ENOG4105CEP	NADH dehydrogenase
BN424_909	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BN424_910	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN424_913	ENOG4108W5M	transcriptional regulator
BN424_914	ENOG4108UW5	maltose o-acetyltransferase
BN424_916	ENOG4107GJV	short-chain dehydrogenase reductase
BN424_918	ENOG4105CPC	Aldo Keto reductase
BN424_92	ENOG4108C33	Resolvase
BN424_920	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
BN424_921	ENOG4105VUF	Transcriptional regulator
BN424_922	ENOG4106KNT	transcriptional regulator
BN424_923	ENOG4105C5Y	PTS System
BN424_924	ENOG4105CS2	ec 3.2.1.21
BN424_929	ENOG4105C5H	ABC transporter
BN424_931	ENOG4107QSI	ABC, transporter
BN424_933	ENOG4105IW1	AmiS UreI transporter
BN424_938	ENOG4107QM2	Aldo Keto reductase
BN424_942	ENOG4105DCF	alanine dehydrogenase
BN424_944	ENOG4107U9T	Pfam:Ribonuclease_BN
BN424_945	ENOG4105D5Q	Arginine ornithine antiporter
BN424_949	ENOG41080E8	Transcriptional regulator, Spx MgsR family
BN424_951	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BN424_952	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BN424_953	ENOG4108UMI	ABC transporter, permease
BN424_954	ENOG4105D01	(LipO)protein
BN424_955	ENOG4105DY9	regulatoR
BN424_958	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
BN424_963	ENOG4105C3K	feS assembly ATPase SufC
BN424_964	ENOG4105JRK	feS assembly protein SufD
BN424_966	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BN424_967	ENOG4105DIW	FeS assembly protein SUFB
BN424_972	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BN424_973	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BN424_975	ENOG4105CID	antiterminator
BN424_976	ENOG4105C5Y	PTS System
BN424_977	ENOG4105CS2	ec 3.2.1.21
BN424_978	ENOG4105FDP	GntR family transcriptional regulator
BN424_98	ENOG4108PZQ	Inner membrane protein YeeR
BN424_983	ENOG4105F3R	pts system mannose fructose sorbose family iid
BN424_990	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
BN424_991	ENOG410667J	hydrolase
BN424_995	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BN424_997	ENOG4107V0Z	fmn reductase