locus-tag	class	description
BN424_1	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BN424_1000	COG0383	alpha-mannosidase activity
BN424_1001	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_1007	COG1174	glycine betaine transport
BN424_1008	COG0517	IMP dehydrogenase activity
BN424_1008	COG1125	glycine betaine transport
BN424_1009	COG0765	amino acid transport
BN424_1010	COG0765	amino acid transport
BN424_1011	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN424_1012	COG1126	abc transporter atp-binding protein
BN424_1013	COG0488	(ABC) transporter
BN424_1014	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BN424_1015	COG0737	Belongs to the 5'-nucleotidase family
BN424_1016	COG4470	Protein conserved in bacteria
BN424_1017	COG0647	UMP catabolic process
BN424_1019	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BN424_1021	COG0492	ferredoxin-NADP+ reductase activity
BN424_1022	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BN424_1023	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BN424_1024	COG1940	carbohydrate kinase activity
BN424_1025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BN424_1026	COG1098	S1 RNA binding domain
BN424_1028	COG0166	Belongs to the GPI family
BN424_104	COG1401	restriction endodeoxyribonuclease activity
BN424_1057	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BN424_1058	COG0477	Major facilitator Superfamily
BN424_1059	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BN424_1060	COG1242	4 iron, 4 sulfur cluster binding
BN424_1061	COG2814	Major facilitator Superfamily
BN424_1062	COG0671	phosphoesterase, PA-phosphatase related
BN424_1065	COG1695	Transcriptional regulator
BN424_1067	COG1388	LysM domain
BN424_1067	COG1705	Flagellar rod assembly protein muramidase FlgJ
BN424_1068	COG1263	PTS System
BN424_1068	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_1069	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BN424_1071	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BN424_1072	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BN424_1073	COG2246	polysaccharide biosynthetic process
BN424_1074	COG1301	dicarboxylic acid transport
BN424_1076	COG0495	leucyl-tRNA aminoacylation
BN424_1079	COG3328	transposase activity
BN424_1080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN424_1082	COG0384	phenazine biosynthesis protein PhzF
BN424_1085	COG2244	polysaccharide biosynthetic process
BN424_1086	COG0626	cystathionine gamma-synthase activity
BN424_1087	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN424_1088	COG0765	amino acid transport
BN424_1089	COG1126	abc transporter atp-binding protein
BN424_1090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BN424_1092	COG0646	methionine synthase
BN424_1092	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BN424_1094	COG1187	pseudouridine synthase activity
BN424_1095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BN424_1096	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN424_1097	COG1979	alcohol dehydrogenase
BN424_1098	COG1979	alcohol dehydrogenase
BN424_1099	COG1285	pathogenesis
BN424_11	COG0359	binds to the 23S rRNA
BN424_1101	COG0500	methyltransferase
BN424_1102	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BN424_1103	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BN424_1105	COG2252	PERMEase
BN424_111	COG1396	sequence-specific DNA binding
BN424_1110	COG0018	arginyl-trna synthetase
BN424_1111	COG1438	arginine binding
BN424_1113	COG0656	L-ascorbic acid biosynthetic process
BN424_1115	COG1253	flavin adenine dinucleotide binding
BN424_1116	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BN424_1118	COG0420	3'-5' exonuclease activity
BN424_1119	COG4717	serine-type aminopeptidase activity
BN424_1122	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BN424_1124	COG0537	adenosine 5'-monophosphoramidase activity
BN424_1125	COG1131	(ABC) transporter
BN424_1126	COG4473	ABC transporter
BN424_1128	COG2814	Major facilitator Superfamily
BN424_1129	COG0510	thiamine kinase activity
BN424_1130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BN424_1132	COG1363	Peptidase, m42
BN424_1133	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BN424_1134	COG0589	response to stress
BN424_1135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN424_1136	COG1674	ftsk spoiiie
BN424_1138	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BN424_1142	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BN424_1142	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BN424_1143	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BN424_1144	COG0237	dephospho-CoA kinase activity
BN424_1145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BN424_1147	COG1484	DNA-dependent DNA replication
BN424_1148	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN424_1149	COG0726	polysaccharide deacetylase
BN424_1150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BN424_1151	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BN424_1152	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BN424_1156	COG3328	transposase activity
BN424_1157	COG3328	transposase activity
BN424_1162	COG1328	CTP reductase activity
BN424_1164	COG0642	Histidine kinase
BN424_1165	COG0745	RESPONSE REGULATOR receiver
BN424_1166	COG1136	(ABC) transporter
BN424_1167	COG0577	efflux transmembrane transporter activity
BN424_1168	COG4166	transmembrane transport
BN424_1169	COG4166	transmembrane transport
BN424_1171	COG1827	regulation of RNA biosynthetic process
BN424_1174	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BN424_1175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BN424_1176	COG1534	Rna-binding protein
BN424_1177	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BN424_1178	COG1713	HD superfamily hydrolase involved in NAD metabolism
BN424_1179	COG0799	negative regulation of ribosome biogenesis
BN424_1180	COG2226	methyltransferase
BN424_1181	COG0514	ATP-dependent DNA helicase (RecQ)
BN424_1182	COG1323	Belongs to the UPF0348 family
BN424_1184	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BN424_1186	COG2001	Belongs to the MraZ family
BN424_1187	COG0275	rRNA processing
BN424_1190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BN424_1192	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BN424_1193	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BN424_1194	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BN424_1195	COG0849	cell division
BN424_1197	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BN424_1198	COG1799	cell septum assembly
BN424_1199	COG0762	integral membrane protein
BN424_1200	COG2302	S4 RNA-binding domain
BN424_1201	COG3599	regulation of cell shape
BN424_1202	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BN424_1203	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BN424_1206	COG1131	(ABC) transporter
BN424_1208	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BN424_1209	COG1278	Cold shock
BN424_1210	COG0028	Belongs to the TPP enzyme family
BN424_1211	COG3527	Alpha-acetolactate decarboxylase
BN424_1213	COG0363	glucosamine-6-phosphate deaminase activity
BN424_1215	COG2261	transglycosylase associated protein
BN424_1216	COG3853	Toxic anion resistance protein (TelA)
BN424_1218	COG0494	nUDIX hydrolase
BN424_1220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BN424_1221	COG1335	isochorismatase
BN424_125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BN424_1253	COG0443	Heat shock 70 kDa protein
BN424_126	COG0598	Magnesium transport protein CorA
BN424_1261	COG1129	ABC transporter
BN424_1262	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BN424_1263	COG4166	transmembrane transport
BN424_1267	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BN424_1268	COG4605	iron ion homeostasis
BN424_1269	COG4604	ABC transporter, ATP-binding protein
BN424_127	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BN424_127	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BN424_1270	COG4607	ABC-type enterochelin transport system periplasmic component
BN424_1271	COG4493	Belongs to the UPF0637 family
BN424_1274	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BN424_1277	COG1956	GAF domain-containing protein
BN424_1279	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BN424_128	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BN424_128	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BN424_1280	COG1104	cysteine desulfurase activity
BN424_1281	COG0301	tRNA thio-modification
BN424_1282	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BN424_1283	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BN424_1284	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BN424_1285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BN424_1287	COG0525	valine-tRNA ligase activity
BN424_1288	COG0285	dihydrofolate synthase activity
BN424_1289	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BN424_129	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_129	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_1290	COG2003	Belongs to the UPF0758 family
BN424_1291	COG1278	Cold shock
BN424_1292	COG1077	Cell shape determining protein MreB Mrl
BN424_1293	COG1792	Involved in formation and maintenance of cell shape
BN424_1296	COG2894	cell division
BN424_1297	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN424_1299	COG0765	amino acid transport
BN424_1301	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BN424_1303	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BN424_1304	COG1609	Transcriptional regulator
BN424_1306	COG3069	C4-dicarboxylate transmembrane transporter activity
BN424_1307	COG0827	DNA restriction-modification system
BN424_1308	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BN424_1309	COG0589	response to stress
BN424_131	COG3715	PTS system
BN424_1312	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BN424_1314	COG1346	cytolysis
BN424_1319	COG1181	Belongs to the D-alanine--D-alanine ligase family
BN424_1319	COG2918	glutathione biosynthetic process
BN424_132	COG3716	PTS system mannose fructose sorbose family IID component
BN424_1322	COG1104	cysteine desulfurase activity
BN424_1324	COG0482	sulfurtransferase activity
BN424_1326	COG0588	phosphoglycerate mutase activity
BN424_1328	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BN424_1329	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_1332	COG1597	lipid kinase activity
BN424_1333	COG1136	(ABC) transporter
BN424_1335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN424_1336	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BN424_1338	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BN424_134	COG2723	6-phospho-beta-galactosidase activity
BN424_1340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BN424_1342	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BN424_1344	COG4585	Histidine kinase
BN424_1345	COG2197	response regulator
BN424_1346	COG0569	domain protein
BN424_1347	COG4841	protein insertion into membrane
BN424_135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_135	COG1263	PTS System
BN424_135	COG2190	(PTS) system
BN424_1353	COG0561	phosphatase activity
BN424_1355	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BN424_136	COG3711	transcriptional antiterminator
BN424_1360	COG1388	LysM domain
BN424_1360	COG3942	CHAP domain
BN424_1362	COG0242	peptide deformylase activity
BN424_1363	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BN424_1364	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN424_137	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN424_1371	COG0039	L-malate dehydrogenase activity
BN424_1372	COG4476	Belongs to the UPF0223 family
BN424_1373	COG0483	inositol monophosphate 1-phosphatase activity
BN424_1374	COG0483	inositol monophosphate 1-phosphatase activity
BN424_1375	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BN424_1376	COG0372	Belongs to the citrate synthase family
BN424_1377	COG0538	isocitrate dehydrogenase activity
BN424_1380	COG4838	Belongs to the UPF0358 family
BN424_1381	COG0772	Belongs to the SEDS family
BN424_1382	COG0772	Belongs to the SEDS family
BN424_1383	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BN424_1384	COG2340	Cysteine-rich secretory protein family
BN424_1385	COG3679	Belongs to the UPF0342 family
BN424_1386	COG4471	UPF0298 protein
BN424_1388	COG0742	ribosomal rna small subunit methyltransferase
BN424_1389	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BN424_1390	COG3480	Lon protease (S16) C-terminal proteolytic domain
BN424_1391	COG1555	photosystem II stabilization
BN424_1391	COG1596	polysaccharide export
BN424_1392	COG2131	deaminase
BN424_1394	COG2333	competence protein COMEC
BN424_1394	COG0658	competence protein
BN424_1396	COG1466	dna polymerase III delta subunit
BN424_1397	COG1466	dna polymerase III delta subunit
BN424_1398	COG0268	Binds directly to 16S ribosomal RNA
BN424_1399	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BN424_1400	COG0556	nucleotide-excision repair
BN424_1404	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_1405	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BN424_1406	COG3623	hexulose-6-phosphate isomerase
BN424_1407	COG0235	Class ii aldolase
BN424_141	COG2188	Transcriptional regulator
BN424_1410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BN424_1411	COG1185	polyribonucleotide nucleotidyltransferase activity
BN424_1412	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BN424_1412	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BN424_1414	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BN424_1415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BN424_142	COG2723	6-phospho-beta-galactosidase activity
BN424_1420	COG1418	mRNA catabolic process
BN424_1423	COG2205	protein histidine kinase activity
BN424_143	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_1440	COG2207	Transcriptional regulator
BN424_1440	COG1917	Cupin 2, conserved barrel domain protein
BN424_1443	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BN424_1447	COG1174	glycine betaine transport
BN424_1452	COG1561	YicC-like family, N-terminal region
BN424_1453	COG0194	GDP metabolic process
BN424_1454	COG1758	RNA polymerase activity
BN424_1455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BN424_1456	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BN424_1458	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BN424_1459	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BN424_1459	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BN424_146	COG1307	EDD domain protein, DegV family
BN424_1460	COG0631	protein serine/threonine phosphatase activity
BN424_1461	COG0515	serine threonine protein kinase
BN424_1461	COG2815	serine threonine protein kinase
BN424_1462	COG1162	GTPase activity
BN424_1463	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BN424_1464	COG1564	THIamine pyrophosphokinase
BN424_1465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BN424_1466	COG1302	Protein conserved in bacteria
BN424_1467	COG1461	Dihydroxyacetone kinase
BN424_1468	COG1760	l-serine dehydratase
BN424_1469	COG1760	l-serine dehydratase
BN424_1470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BN424_1471	COG0416	fatty acid biosynthetic process
BN424_1472	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BN424_1473	COG0571	ribonuclease III activity
BN424_1474	COG1196	nuclear chromosome segregation
BN424_1475	COG0561	phosphatase activity
BN424_1476	COG0552	protein localization to endoplasmic reticulum
BN424_1477	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BN424_1478	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BN424_1479	COG0228	four-way junction DNA binding
BN424_1480	COG1837	Belongs to the UPF0109 family
BN424_1481	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BN424_1482	COG0336	Belongs to the RNA methyltransferase TrmD family
BN424_1483	COG0335	large ribosomal subunit rRNA binding
BN424_1484	COG0582	viral genome integration into host DNA
BN424_1493	COG0789	Transcriptional regulator
BN424_1495	COG0667	Aldo Keto reductase
BN424_1496	COG0789	Transcriptional regulator
BN424_1497	COG1064	alcohol dehydrogenase
BN424_1498	COG0583	DNA-binding transcription factor activity
BN424_1504	COG1666	GTP binding
BN424_1505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN424_1506	COG0561	phosphatase activity
BN424_1507	COG1073	alpha beta
BN424_1508	COG2151	metal-sulfur cluster biosynthetic enzyme
BN424_1509	COG0628	permease
BN424_151	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BN424_1510	COG0589	response to stress
BN424_1512	COG0542	response to heat
BN424_1514	COG0587	DNA-directed DNA polymerase activity
BN424_1515	COG0587	DNA-directed DNA polymerase activity
BN424_1516	COG0205	6-phosphofructokinase activity
BN424_1519	COG0745	RESPONSE REGULATOR receiver
BN424_1521	COG2996	Protein conserved in bacteria
BN424_1522	COG0735	belongs to the Fur family
BN424_1524	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BN424_1526	COG0019	diaminopimelate decarboxylase activity
BN424_1528	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BN424_1529	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BN424_153	COG1131	(ABC) transporter
BN424_1530	COG1187	pseudouridine synthase activity
BN424_1531	COG0745	RESPONSE REGULATOR receiver
BN424_1532	COG5002	protein histidine kinase activity
BN424_1533	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BN424_1536	COG0514	ATP-dependent DNA helicase (RecQ)
BN424_1539	COG0539	negative regulation of cytoplasmic translation
BN424_1540	COG1160	GTP binding
BN424_1542	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BN424_1543	COG0457	Tetratricopeptide repeat
BN424_1544	COG5582	Belongs to the UPF0302 family
BN424_1545	COG1694	Mazg nucleotide pyrophosphohydrolase
BN424_1546	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BN424_1547	COG0617	tRNA 3'-terminal CCA addition
BN424_155	COG1131	(ABC) transporter
BN424_1551	COG0842	Transport permease protein
BN424_1552	COG1131	(ABC) transporter
BN424_1554	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BN424_1555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BN424_1558	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BN424_1560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BN424_1560	COG1199	ATP-dependent helicase activity
BN424_1564	COG3935	DnaD domain protein
BN424_1565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BN424_1566	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BN424_1567	COG3331	DNA recombination
BN424_1568	COG4474	Belongs to the UPF0398 family
BN424_1569	COG3599	regulation of cell shape
BN424_157	COG3290	protein histidine kinase activity
BN424_1570	COG0116	Belongs to the methyltransferase superfamily
BN424_1571	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BN424_1573	COG0328	RNA-DNA hybrid ribonuclease activity
BN424_1576	COG1278	Cold shock
BN424_158	COG3279	Response regulator of the LytR AlgR family
BN424_1583	COG0488	(ABC) transporter
BN424_1584	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BN424_1586	COG1272	protein, Hemolysin III
BN424_1587	COG1307	EDD domain protein, DegV family
BN424_1588	COG2755	lipolytic protein G-D-S-L family
BN424_1590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BN424_1592	COG0813	purine-nucleoside phosphorylase activity
BN424_1593	COG3409	Peptidoglycan-binding domain 1 protein
BN424_1593	COG0793	Belongs to the peptidase S41A family
BN424_1595	COG0681	Belongs to the peptidase S26 family
BN424_1598	COG0758	DNA mediated transformation
BN424_1599	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BN424_160	COG0384	phenazine biosynthesis protein PhzF
BN424_1600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BN424_1601	COG4974	Belongs to the 'phage' integrase family
BN424_1602	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BN424_1603	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BN424_1607	COG0187	DNA topoisomerase II activity
BN424_1608	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BN424_1610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BN424_1613	COG1227	inorganic diphosphatase activity
BN424_1614	COG3275	phosphorelay sensor kinase activity
BN424_1615	COG3279	Response regulator of the LytR AlgR family
BN424_1618	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BN424_1620	COG3328	transposase activity
BN424_1628	COG3711	transcriptional antiterminator
BN424_163	COG5002	protein histidine kinase activity
BN424_163	COG3850	Histidine kinase
BN424_1630	COG1394	ATPase activity, coupled to movement of substances
BN424_1631	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
BN424_1632	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BN424_1633	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
BN424_1634	COG1527	subunit (C
BN424_1636	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BN424_1637	COG1269	ATP hydrolysis coupled proton transport
BN424_1641	COG0659	secondary active sulfate transmembrane transporter activity
BN424_1645	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN424_1646	COG0798	PFAM Bile acid sodium symporter
BN424_165	COG1136	(ABC) transporter
BN424_165	COG0577	efflux transmembrane transporter activity
BN424_1650	COG1846	Transcriptional regulator
BN424_1651	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BN424_1652	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BN424_1661	COG4684	Psort location CytoplasmicMembrane, score
BN424_1664	COG1335	isochorismatase
BN424_1667	COG1316	TRANSCRIPTIONal
BN424_167	COG4895	conserved protein (DUF2196)
BN424_1671	COG1116	anion transmembrane transporter activity
BN424_1672	COG4120	Belongs to the binding-protein-dependent transport system permease family
BN424_1675	COG0419	ATPase involved in DNA repair
BN424_1679	COG0159	tryptophan synthase activity
BN424_168	COG4807	Protein conserved in bacteria
BN424_1680	COG0133	tryptophan synthase activity
BN424_1681	COG0135	phosphoribosylanthranilate isomerase activity
BN424_1682	COG0134	indole-3-glycerol-phosphate synthase activity
BN424_1683	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BN424_1684	COG0512	Glutamine amidotransferase of anthranilate synthase
BN424_1685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BN424_1692	COG4912	Dna alkylation repair
BN424_1696	COG0326	Molecular chaperone. Has ATPase activity
BN424_1697	COG0584	glycerophosphoryl diester phosphodiesterase
BN424_1700	COG1120	ATPase activity
BN424_1701	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BN424_1702	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BN424_1703	COG0492	ferredoxin-NADP+ reductase activity
BN424_1704	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BN424_1709	COG0372	Belongs to the citrate synthase family
BN424_1710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BN424_1713	COG0543	2 iron, 2 sulfur cluster binding
BN424_1714	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BN424_1715	COG0505	Belongs to the CarA family
BN424_1716	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BN424_1717	COG0540	Belongs to the ATCase OTCase family
BN424_1718	COG2233	PERMEase
BN424_1719	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BN424_1720	COG0564	pseudouridine synthase activity
BN424_1721	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BN424_1723	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BN424_1724	COG2508	Transcriptional regulator
BN424_1725	COG0549	Belongs to the carbamate kinase family
BN424_1728	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BN424_1729	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BN424_173	COG0519	Catalyzes the synthesis of GMP from XMP
BN424_1730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BN424_1731	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BN424_1732	COG3257	ureidoglycine aminohydrolase activity
BN424_1734	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN424_1736	COG3104	oligopeptide transport
BN424_1739	COG4990	cell redox homeostasis
BN424_1740	COG1074	ATP-dependent DNA helicase activity
BN424_1741	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BN424_1742	COG3340	Belongs to the peptidase S51 family
BN424_1746	COG2195	Cleaves the N-terminal amino acid of tripeptides
BN424_1747	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BN424_1748	COG2384	SAM-dependent methyltransferase
BN424_1749	COG1388	LysM domain
BN424_1749	COG1705	Flagellar rod assembly protein muramidase FlgJ
BN424_1754	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BN424_1755	COG0358	DNA primase activity
BN424_1756	COG1132	(ABC) transporter
BN424_1758	COG0751	glycine-tRNA ligase activity
BN424_1759	COG0752	glycyl-tRNA synthetase alpha subunit
BN424_176	COG1073	alpha beta
BN424_1760	COG3764	Sortase (surface protein transpeptidase)
BN424_1762	COG1381	Involved in DNA repair and RecF pathway recombination
BN424_1763	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BN424_1765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BN424_1766	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BN424_1768	COG1702	phosphate starvation-inducible protein PhoH
BN424_1771	COG1610	YqeY-like protein
BN424_1772	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BN424_1773	COG0735	belongs to the Fur family
BN424_1774	COG0517	IMP dehydrogenase activity
BN424_1775	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BN424_1776	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BN424_1777	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BN424_1778	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BN424_1779	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BN424_1780	COG0049	tRNA binding
BN424_1781	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BN424_1784	COG1704	LemA family
BN424_1786	COG0745	RESPONSE REGULATOR receiver
BN424_1789	COG2205	protein histidine kinase activity
BN424_179	COG1028	Short-chain dehydrogenase reductase Sdr
BN424_1791	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BN424_1792	COG0778	Nitroreductase
BN424_1793	COG1714	RDD family
BN424_1795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BN424_1796	COG0124	histidyl-tRNA synthetase
BN424_1797	COG4991	sh3 domain protein
BN424_1797	COG3103	Sh3 type 3 domain protein
BN424_1797	COG0860	N-Acetylmuramoyl-L-alanine amidase
BN424_1798	COG1490	D-aminoacyl-tRNA deacylase activity
BN424_1799	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BN424_180	COG4708	membrane
BN424_1803	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BN424_1804	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BN424_1805	COG2264	protein methyltransferase activity
BN424_1807	COG2094	Belongs to the DNA glycosylase MPG family
BN424_1809	COG0246	Mannitol dehydrogenase
BN424_181	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BN424_1810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_1811	COG3711	transcriptional antiterminator
BN424_1812	COG2213	PTS system mannitol-specific
BN424_1826	COG4974	Belongs to the 'phage' integrase family
BN424_1829	COG5263	repeat protein
BN424_1829	COG5632	N-Acetylmuramoyl-L-alanine amidase
BN424_184	COG0191	fructose-bisphosphate aldolase activity
BN424_185	COG1187	pseudouridine synthase activity
BN424_1855	COG2369	cell adhesion
BN424_188	COG2824	Alkylphosphonate utilization operon protein PhnA
BN424_1894	COG4974	Belongs to the 'phage' integrase family
BN424_1895	COG0481	GTPase activity
BN424_1896	COG0484	heat shock protein binding
BN424_1897	COG0443	Heat shock 70 kDa protein
BN424_1898	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BN424_19	COG0297	glycogen (starch) synthase activity
BN424_19	COG0438	transferase activity, transferring glycosyl groups
BN424_190	COG0737	Belongs to the 5'-nucleotidase family
BN424_1900	COG1051	belongs to the nudix hydrolase family
BN424_1905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BN424_1906	COG0196	riboflavin kinase activity
BN424_1907	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BN424_1908	COG1307	EDD domain protein, DegV family
BN424_1909	COG1597	lipid kinase activity
BN424_1915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BN424_1918	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BN424_1919	COG0195	Participates in both transcription termination and antitermination
BN424_1920	COG0779	Required for maturation of 30S ribosomal subunits
BN424_1922	COG2176	DNA-directed DNA polymerase activity
BN424_1923	COG0442	prolyl-tRNA aminoacylation
BN424_1924	COG0750	zinc metalloprotease
BN424_1925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BN424_1926	COG4589	Belongs to the CDS family
BN424_1928	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BN424_193	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_1930	COG0233	cytoplasmic translational termination
BN424_1931	COG0528	UMP kinase activity
BN424_1932	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BN424_1933	COG0052	Belongs to the universal ribosomal protein uS2 family
BN424_1935	COG2195	Cleaves the N-terminal amino acid of tripeptides
BN424_1936	COG4166	transmembrane transport
BN424_1939	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BN424_194	COG2723	6-phospho-beta-galactosidase activity
BN424_1941	COG0419	ATPase involved in DNA repair
BN424_1944	COG0204	Acyl-transferase
BN424_1945	COG1902	pentaerythritol trinitrate reductase activity
BN424_1946	COG1132	(ABC) transporter
BN424_1947	COG1132	(ABC) transporter
BN424_1948	COG3763	UPF0154 protein
BN424_195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_1951	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BN424_1954	COG2433	Pfam Transposase IS66
BN424_1956	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BN424_1957	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BN424_1957	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BN424_1958	COG2153	protein acetylation
BN424_196	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BN424_1960	COG5416	Lipopolysaccharide assembly protein A domain
BN424_1961	COG0300	oxidoreductase activity
BN424_1962	COG1234	tRNA 3'-trailer cleavage
BN424_1964	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BN424_1965	COG3394	polysaccharide catabolic process
BN424_1968	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BN424_197	COG1953	Uracil, thiamine, allantoin
BN424_1970	COG1937	Protein conserved in bacteria
BN424_1971	COG0425	Belongs to the sulfur carrier protein TusA family
BN424_1971	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BN424_1972	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN424_1973	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BN424_1974	COG1131	(ABC) transporter
BN424_1976	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BN424_1977	COG1959	2 iron, 2 sulfur cluster binding
BN424_1979	COG1349	DNA-binding transcription factor activity
BN424_1980	COG1105	Belongs to the carbohydrate kinase PfkB family
BN424_1981	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_1981	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_1981	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_1984	COG1131	(ABC) transporter
BN424_1985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BN424_1987	COG1126	abc transporter atp-binding protein
BN424_1988	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN424_1989	COG2608	mercury ion transmembrane transporter activity
BN424_1990	COG3682	Transcriptional regulator
BN424_1994	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BN424_1995	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BN424_1996	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BN424_2	COG0592	DNA-directed DNA polymerase activity
BN424_2006	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BN424_2007	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BN424_2009	COG0544	peptidyl-prolyl cis-trans isomerase activity
BN424_2015	COG0825	malonyl-CoA metabolic process
BN424_2016	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BN424_2017	COG0439	Biotin carboxylase
BN424_2018	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BN424_2020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BN424_2022	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BN424_2025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BN424_2026	COG1846	Transcriptional regulator
BN424_2028	COG0745	RESPONSE REGULATOR receiver
BN424_2029	COG5002	protein histidine kinase activity
BN424_2029	COG3850	Histidine kinase
BN424_2030	COG0577	efflux transmembrane transporter activity
BN424_2031	COG1136	(ABC) transporter
BN424_2032	COG1193	negative regulation of DNA recombination
BN424_2038	COG0789	Transcriptional regulator
BN424_2039	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BN424_2041	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BN424_2042	COG0584	glycerophosphoryl diester phosphodiesterase
BN424_2043	COG0166	Belongs to the GPI family
BN424_2044	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BN424_2046	COG1940	carbohydrate kinase activity
BN424_2047	COG1940	carbohydrate kinase activity
BN424_2049	COG0705	Rhomboid family
BN424_2049	COG0457	Tetratricopeptide repeat
BN424_2050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BN424_2051	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BN424_2056	COG4485	Bacterial membrane protein, YfhO
BN424_2058	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BN424_2063	COG0513	Belongs to the DEAD box helicase family
BN424_2064	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BN424_2067	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BN424_2068	COG4109	DRTGG domain
BN424_2069	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BN424_207	COG3711	transcriptional antiterminator
BN424_2070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BN424_2072	COG1454	alcohol dehydrogenase
BN424_2072	COG1012	belongs to the aldehyde dehydrogenase family
BN424_2074	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BN424_2074	COG0392	lysyltransferase activity
BN424_2075	COG1862	Preprotein translocase
BN424_2076	COG0343	queuine tRNA-ribosyltransferase activity
BN424_2077	COG1309	transcriptional regulator
BN424_2078	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BN424_2079	COG2255	four-way junction helicase activity
BN424_2080	COG0632	four-way junction helicase activity
BN424_2085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BN424_2089	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BN424_2090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BN424_2092	COG1692	metallophosphoesterase
BN424_2093	COG1418	mRNA catabolic process
BN424_2094	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BN424_2097	COG1058	Belongs to the CinA family
BN424_2097	COG1546	Belongs to the CinA family
BN424_2099	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BN424_21	COG3711	transcriptional antiterminator
BN424_2100	COG0025	NhaP-type Na H and K H
BN424_2101	COG1426	Protein conserved in bacteria
BN424_2103	COG0612	Peptidase, M16
BN424_2104	COG0612	Peptidase, M16
BN424_2109	COG1744	ABC transporter substrate-binding protein PnrA-like
BN424_2110	COG1674	ftsk spoiiie
BN424_2110	COG1280	lysine exporter protein (LysE YggA)
BN424_2112	COG0551	DNA topoisomerase type I activity
BN424_2112	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BN424_2113	COG0551	DNA topoisomerase type I activity
BN424_2113	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BN424_2115	COG1254	Belongs to the acylphosphatase family
BN424_2116	COG0706	membrane insertase activity
BN424_2117	COG5002	protein histidine kinase activity
BN424_2118	COG0745	RESPONSE REGULATOR receiver
BN424_212	COG1686	Belongs to the peptidase S11 family
BN424_2120	COG5632	N-Acetylmuramoyl-L-alanine amidase
BN424_2120	COG5263	repeat protein
BN424_2141	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BN424_2144	COG5518	Phage portal protein
BN424_215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BN424_216	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BN424_2178	COG4974	Belongs to the 'phage' integrase family
BN424_2179	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BN424_2180	COG2195	Cleaves the N-terminal amino acid of tripeptides
BN424_2184	COG0577	efflux transmembrane transporter activity
BN424_2184	COG1136	(ABC) transporter
BN424_2186	COG0497	DNA recombination
BN424_2189	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BN424_2191	COG1722	exodeoxyribonuclease VII activity
BN424_2192	COG1570	exodeoxyribonuclease VII activity
BN424_2193	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BN424_2194	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BN424_2195	COG1302	Protein conserved in bacteria
BN424_2196	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BN424_2197	COG0006	proline dipeptidase activity
BN424_2202	COG4537	Required for transformation and DNA binding
BN424_2204	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BN424_2205	COG0583	DNA-binding transcription factor activity
BN424_2206	COG2855	membrane
BN424_2207	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN424_2211	COG0217	transcriptional regulatory protein
BN424_2212	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BN424_2216	COG1388	LysM domain
BN424_2216	COG0791	NLP P60 protein
BN424_2216	COG3103	Sh3 type 3 domain protein
BN424_2217	COG0519	Catalyzes the synthesis of GMP from XMP
BN424_2219	COG1122	ATPase activity
BN424_2220	COG4120	Belongs to the binding-protein-dependent transport system permease family
BN424_2224	COG1609	Transcriptional regulator
BN424_2226	COG0006	proline dipeptidase activity
BN424_2228	COG0668	transmembrane transport
BN424_2232	COG0517	IMP dehydrogenase activity
BN424_2237	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BN424_2239	COG1719	4-vinyl reductase, 4VR
BN424_2240	COG1668	transmembrane transport
BN424_2241	COG4152	abc transporter atp-binding protein
BN424_2242	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BN424_2243	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BN424_2244	COG1696	Membrane protein involved in D-alanine export
BN424_2245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BN424_2247	COG0322	excinuclease ABC activity
BN424_2253	COG3118	belongs to the thioredoxin family
BN424_2254	COG1193	negative regulation of DNA recombination
BN424_2256	COG1286	toxin biosynthetic process
BN424_2258	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BN424_2259	COG0531	amino acid
BN424_2260	COG0596	Alpha beta hydrolase
BN424_2261	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN424_2261	COG0072	phenylalanine-tRNA ligase activity
BN424_2262	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BN424_2267	COG1733	regulation of RNA biosynthetic process
BN424_2268	COG0655	NAD(P)H dehydrogenase (quinone) activity
BN424_227	COG0588	phosphoglycerate mutase activity
BN424_2270	COG1595	DNA-templated transcription, initiation
BN424_2272	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN424_2273	COG1196	nuclear chromosome segregation
BN424_2273	COG0741	lytic transglycosylase activity
BN424_2273	COG0739	heme binding
BN424_2274	COG1609	Transcriptional regulator
BN424_2276	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BN424_2277	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BN424_2278	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BN424_2279	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BN424_2282	COG3328	transposase activity
BN424_2283	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BN424_2285	COG1486	melibiose metabolic process
BN424_2288	COG0589	response to stress
BN424_2289	COG0589	response to stress
BN424_2293	COG0778	Nitroreductase
BN424_2294	COG1846	Transcriptional regulator
BN424_2297	COG0737	Belongs to the 5'-nucleotidase family
BN424_2301	COG1349	DNA-binding transcription factor activity
BN424_2305	COG1349	DNA-binding transcription factor activity
BN424_2307	COG0191	fructose-bisphosphate aldolase activity
BN424_2308	COG0673	inositol 2-dehydrogenase activity
BN424_2311	COG3962	Belongs to the TPP enzyme family
BN424_2312	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN424_2313	COG3718	enzyme involved in inositol metabolism
BN424_2317	COG3764	Sortase (surface protein transpeptidase)
BN424_2318	COG5002	protein histidine kinase activity
BN424_2319	COG0745	RESPONSE REGULATOR receiver
BN424_2324	COG3682	Transcriptional regulator
BN424_2325	COG2918	glutathione biosynthetic process
BN424_2325	COG1181	Belongs to the D-alanine--D-alanine ligase family
BN424_2330	COG0791	NLP P60 protein
BN424_2330	COG3883	PFAM NLP P60 protein
BN424_2331	COG4942	peptidase
BN424_2332	COG2217	Heavy metal translocating P-type atpase
BN424_2333	COG2217	Heavy metal translocating P-type atpase
BN424_2338	COG0577	efflux transmembrane transporter activity
BN424_2339	COG1136	(ABC) transporter
BN424_2344	COG3328	transposase activity
BN424_2347	COG4555	ABC transporter
BN424_236	COG2723	6-phospho-beta-galactosidase activity
BN424_2360	COG4942	peptidase
BN424_2360	COG1388	LysM domain
BN424_2371	COG1349	DNA-binding transcription factor activity
BN424_2372	COG1942	4-Oxalocrotonate Tautomerase
BN424_2374	COG1129	ABC transporter
BN424_2378	COG0004	ammonium transporteR
BN424_2379	COG0347	Belongs to the P(II) protein family
BN424_238	COG3469	chitinase activity
BN424_2381	COG4753	response regulator
BN424_2381	COG2207	Transcriptional regulator
BN424_2382	COG2972	Histidine kinase
BN424_2385	COG0395	ABC-type sugar transport system, permease component
BN424_2387	COG2205	protein histidine kinase activity
BN424_2388	COG0745	RESPONSE REGULATOR receiver
BN424_239	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_2390	COG4608	Belongs to the ABC transporter superfamily
BN424_2391	COG0444	Belongs to the ABC transporter superfamily
BN424_2392	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BN424_2393	COG0601	transmembrane transport
BN424_2395	COG0180	Tryptophanyl-tRNA synthetase
BN424_2396	COG0095	Lipoate-protein ligase
BN424_2397	COG1234	tRNA 3'-trailer cleavage
BN424_2401	COG1363	Peptidase, m42
BN424_2403	COG0527	aspartate kinase activity
BN424_2404	COG0367	asparagine synthase
BN424_2406	COG3142	Participates in the control of copper homeostasis
BN424_2407	COG0726	polysaccharide deacetylase
BN424_2409	COG1368	sulfuric ester hydrolase activity
BN424_2412	COG0083	homoserine kinase activity
BN424_2413	COG0460	homoserine dehydrogenase
BN424_2414	COG4703	Protein of unknown function (DUF1797)
BN424_2415	COG0436	Aminotransferase
BN424_2416	COG2084	Dehydrogenase
BN424_2418	COG0438	transferase activity, transferring glycosyl groups
BN424_2419	COG0438	transferase activity, transferring glycosyl groups
BN424_2420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BN424_2424	COG0542	response to heat
BN424_2425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BN424_2428	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BN424_2429	COG1253	flavin adenine dinucleotide binding
BN424_2432	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN424_2433	COG0628	permease
BN424_2435	COG1363	Peptidase, m42
BN424_2437	COG2153	protein acetylation
BN424_2439	COG2239	Acts as a magnesium transporter
BN424_244	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BN424_2440	COG0564	pseudouridine synthase activity
BN424_2442	COG2357	RelA SpoT domain protein
BN424_2443	COG4116	CYTH
BN424_2445	COG1164	Oligoendopeptidase f
BN424_2448	COG4862	establishment of competence for transformation
BN424_2449	COG1393	Belongs to the ArsC family
BN424_245	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BN424_2450	COG3328	transposase activity
BN424_2451	COG2848	UPF0210 protein
BN424_2452	COG3830	Belongs to the UPF0237 family
BN424_2453	COG3118	belongs to the thioredoxin family
BN424_2454	COG0025	NhaP-type Na H and K H
BN424_2456	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BN424_2458	COG1307	EDD domain protein, DegV family
BN424_2459	COG3012	SEC-C Motif Domain Protein
BN424_246	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BN424_2460	COG0438	transferase activity, transferring glycosyl groups
BN424_2462	COG3973	AAA domain
BN424_2463	COG3973	AAA domain
BN424_247	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BN424_2478	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BN424_248	COG0287	Prephenate dehydrogenase
BN424_2481	COG0640	Transcriptional regulator
BN424_2484	COG2723	6-phospho-beta-galactosidase activity
BN424_2485	COG2746	aminoglycoside 3-N-acetyltransferase activity
BN424_2488	COG0697	spore germination
BN424_249	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BN424_2490	COG3684	Belongs to the aldolase LacD family
BN424_2491	COG1105	Belongs to the carbohydrate kinase PfkB family
BN424_2493	COG3716	PTS system mannose fructose sorbose family IID component
BN424_2494	COG3715	PTS system
BN424_2496	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_2497	COG2222	sugar isomerase
BN424_250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BN424_2500	COG1929	Belongs to the glycerate kinase type-1 family
BN424_2501	COG1053	succinate dehydrogenase
BN424_2502	COG2217	Heavy metal translocating P-type atpase
BN424_2508	COG1131	(ABC) transporter
BN424_251	COG0077	Prephenate dehydratase
BN424_252	COG4166	transmembrane transport
BN424_2537	COG0366	Alpha amylase catalytic
BN424_2538	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BN424_2539	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BN424_2542	COG3833	ABC-type maltose transport systems, permease component
BN424_2543	COG1175	transmembrane transport
BN424_2544	COG2182	Extracellular solute-binding protein
BN424_2547	COG1609	Transcriptional regulator
BN424_2548	COG0735	belongs to the Fur family
BN424_2549	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BN424_255	COG2213	PTS system mannitol-specific
BN424_2550	COG4129	membrane
BN424_2552	COG3557	Belongs to the UPF0374 family
BN424_2553	COG3711	transcriptional antiterminator
BN424_2555	COG1194	a g-specific adenine glycosylase
BN424_2556	COG2137	regulation of response to DNA damage stimulus
BN424_2557	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN424_2558	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN424_2559	COG0628	permease
BN424_256	COG3711	transcriptional antiterminator
BN424_2562	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN424_2563	COG2195	Cleaves the N-terminal amino acid of tripeptides
BN424_2566	COG1428	Deoxynucleoside kinase
BN424_2567	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BN424_2569	COG1316	TRANSCRIPTIONal
BN424_257	COG3711	transcriptional antiterminator
BN424_2572	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BN424_2577	COG3328	transposase activity
BN424_2578	COG3328	transposase activity
BN424_2579	COG3328	transposase activity
BN424_2580	COG1295	ribonuclease BN
BN424_2581	COG0024	Methionine aminopeptidase
BN424_2582	COG0716	FMN binding
BN424_2586	COG2309	aminopeptidase activity
BN424_2592	COG1447	Phosphotransferase system cellobiose-specific component IIA
BN424_2593	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_2594	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_2595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_2596	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_2597	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BN424_2597	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BN424_2598	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BN424_2598	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BN424_2600	COG0673	inositol 2-dehydrogenase activity
BN424_2605	COG5632	N-Acetylmuramoyl-L-alanine amidase
BN424_2605	COG5263	repeat protein
BN424_2634	COG0629	single-stranded DNA binding
BN424_2638	COG0863	Belongs to the N(4) N(6)-methyltransferase family
BN424_266	COG0110	maltose O-acetyltransferase activity
BN424_2665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BN424_2666	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN424_2667	COG1597	lipid kinase activity
BN424_2668	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BN424_2669	COG0154	amidase activity
BN424_2670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BN424_2671	COG4851	CamS sex pheromone cAM373 precursor
BN424_2672	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BN424_2673	COG0210	DNA helicase
BN424_2678	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BN424_2679	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BN424_268	COG0346	lactoylglutathione lyase activity
BN424_2681	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BN424_2683	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BN424_2684	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BN424_2685	COG0346	lactoylglutathione lyase activity
BN424_2689	COG0148	phosphopyruvate hydratase activity
BN424_2690	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BN424_2691	COG0149	triose-phosphate isomerase activity
BN424_2695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BN424_2699	COG0740	serine-type endopeptidase activity
BN424_27	COG0305	Participates in initiation and elongation during chromosome replication
BN424_2701	COG1481	regulation of sporulation
BN424_2703	COG1660	Displays ATPase and GTPase activities
BN424_2704	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BN424_2705	COG0492	ferredoxin-NADP+ reductase activity
BN424_2707	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BN424_2708	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BN424_2709	COG0546	phosphoglycolate phosphatase activity
BN424_2710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BN424_2711	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BN424_2712	COG1950	PFAM Membrane protein of
BN424_2715	COG3595	metallopeptidase activity
BN424_2716	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN424_2719	COG0704	Plays a role in the regulation of phosphate uptake
BN424_272	COG2235	arginine
BN424_2720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BN424_2721	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BN424_2722	COG0581	inorganic phosphate transmembrane transporter activity
BN424_2723	COG0573	inorganic phosphate transmembrane transporter activity
BN424_2724	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BN424_2725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BN424_2727	COG5002	protein histidine kinase activity
BN424_2728	COG0745	RESPONSE REGULATOR receiver
BN424_2730	COG3103	Sh3 type 3 domain protein
BN424_2730	COG0791	NLP P60 protein
BN424_2730	COG1388	LysM domain
BN424_2731	COG2177	Part of the ABC transporter FtsEX involved in
BN424_2732	COG2884	Cell division ATP-binding protein ftsE
BN424_2733	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BN424_2734	COG0653	protein targeting
BN424_2737	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BN424_2738	COG1307	EDD domain protein, DegV family
BN424_2739	COG1739	Uncharacterized protein family UPF0029
BN424_2740	COG1316	TRANSCRIPTIONal
BN424_2741	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BN424_2744	COG0363	glucosamine-6-phosphate deaminase activity
BN424_2747	COG1309	transcriptional regulator
BN424_2748	COG1368	sulfuric ester hydrolase activity
BN424_2749	COG0463	Glycosyl transferase, family 2
BN424_2750	COG2246	polysaccharide biosynthetic process
BN424_2752	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BN424_2753	COG1215	transferase activity, transferring glycosyl groups
BN424_2755	COG1091	dTDP-4-dehydrorhamnose reductase activity
BN424_2758	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BN424_276	COG0549	Belongs to the carbamate kinase family
BN424_2761	COG1215	transferase activity, transferring glycosyl groups
BN424_2766	COG1368	sulfuric ester hydrolase activity
BN424_2767	COG1705	Flagellar rod assembly protein muramidase FlgJ
BN424_2767	COG1388	LysM domain
BN424_2768	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BN424_2770	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BN424_2771	COG0459	protein refolding
BN424_2772	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BN424_2773	COG1266	CAAX protease self-immunity
BN424_2776	COG0488	(ABC) transporter
BN424_2777	COG1316	TRANSCRIPTIONal
BN424_2778	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BN424_2781	COG1214	PFAM Peptidase M22, glycoprotease
BN424_2789	COG3764	Sortase (surface protein transpeptidase)
BN424_2799	COG0494	nUDIX hydrolase
BN424_28	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BN424_280	COG3397	chitin binding
BN424_2800	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN424_2801	COG3328	transposase activity
BN424_2809	COG3878	Protein conserved in bacteria
BN424_2811	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BN424_2813	COG3328	transposase activity
BN424_2815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BN424_2819	COG1744	ABC transporter substrate-binding protein PnrA-like
BN424_2822	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BN424_2823	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BN424_2825	COG1609	Transcriptional regulator
BN424_2828	COG1846	Transcriptional regulator
BN424_283	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN424_2832	COG1611	Belongs to the LOG family
BN424_2833	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BN424_2835	COG2315	Protein conserved in bacteria
BN424_2837	COG2378	regulation of single-species biofilm formation
BN424_2840	COG1181	Belongs to the D-alanine--D-alanine ligase family
BN424_2841	COG0726	polysaccharide deacetylase
BN424_2845	COG0254	rRNA binding
BN424_2846	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BN424_2847	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BN424_2848	COG0504	CTP synthase activity
BN424_2849	COG3343	RNA polymerase activity
BN424_2851	COG2390	Transcriptional regulator
BN424_2853	COG0022	dehydrogenase e1 component
BN424_2854	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BN424_2855	COG0095	Lipoate-protein ligase
BN424_2856	COG1078	dGTPase activity
BN424_2857	COG0561	phosphatase activity
BN424_2858	COG1942	4-Oxalocrotonate Tautomerase
BN424_2859	COG1764	response to oxidative stress
BN424_2862	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN424_2864	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_2865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_2867	COG1446	asparaginase
BN424_2873	COG0076	glutamate decarboxylase activity
BN424_2874	COG0531	amino acid
BN424_2876	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BN424_2877	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BN424_2879	COG1464	Belongs to the NlpA lipoprotein family
BN424_2880	COG1803	Methylglyoxal synthase
BN424_2881	COG2271	Major facilitator Superfamily
BN424_2882	COG0738	Major facilitator superfamily
BN424_2883	COG0710	3-dehydroquinate dehydratase activity
BN424_2884	COG0738	Major facilitator superfamily
BN424_2887	COG0583	DNA-binding transcription factor activity
BN424_2891	COG1879	ABC-type sugar transport system periplasmic component
BN424_2892	COG1172	Belongs to the binding-protein-dependent transport system permease family
BN424_2894	COG1869	D-ribose catabolic process
BN424_2895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN424_2896	COG1609	Transcriptional regulator
BN424_29	COG4565	transcriptional regulatory protein
BN424_2909	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BN424_2913	COG2249	NAD(P)H dehydrogenase (quinone) activity
BN424_2918	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BN424_292	COG1388	LysM domain
BN424_292	COG0791	NLP P60 protein
BN424_2923	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BN424_2923	COG0519	Catalyzes the synthesis of GMP from XMP
BN424_2924	COG1072	(Pantothenic acid kinase))
BN424_2928	COG1304	FMN binding
BN424_2929	COG0604	alcohol dehydrogenase
BN424_293	COG0477	Major facilitator Superfamily
BN424_2932	COG1607	acyl-coa hydrolase
BN424_2945	COG0588	phosphoglycerate mutase activity
BN424_2947	COG2116	formate transmembrane transporter activity
BN424_295	COG3842	ATPase activity
BN424_2956	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BN424_2957	COG0628	permease
BN424_2972	COG1263	PTS System
BN424_2972	COG2190	(PTS) system
BN424_2972	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_2973	COG3711	transcriptional antiterminator
BN424_2975	COG0693	protein deglycase activity
BN424_2978	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BN424_2981	COG0577	efflux transmembrane transporter activity
BN424_2982	COG1136	(ABC) transporter
BN424_2989	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BN424_299	COG0371	Dehydrogenase
BN424_2990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BN424_2994	COG5002	protein histidine kinase activity
BN424_2995	COG0745	RESPONSE REGULATOR receiver
BN424_2999	COG3964	amidohydrolase
BN424_3	COG2501	S4 domain
BN424_30	COG3290	protein histidine kinase activity
BN424_300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN424_3002	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_301	COG0765	amino acid transport
BN424_3010	COG2188	Transcriptional regulator
BN424_3012	COG2723	6-phospho-beta-galactosidase activity
BN424_3013	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3015	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN424_3020	COG3158	transport of potassium into the cell
BN424_3022	COG1940	carbohydrate kinase activity
BN424_3024	COG0383	alpha-mannosidase activity
BN424_3028	COG1121	(ABC) transporter
BN424_3030	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BN424_3030	COG3291	Pkd domain containing protein
BN424_3031	COG2188	Transcriptional regulator
BN424_3032	COG2723	6-phospho-beta-galactosidase activity
BN424_3033	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3034	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BN424_3035	COG0730	response to heat
BN424_3037	COG1131	(ABC) transporter
BN424_3039	COG5492	domain, Protein
BN424_3047	COG3711	transcriptional antiterminator
BN424_3051	COG4509	Sortase family
BN424_3054	COG5386	Cell surface protein
BN424_3055	COG5386	Cell surface protein
BN424_3058	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BN424_3061	COG0438	transferase activity, transferring glycosyl groups
BN424_3062	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BN424_3063	COG1215	transferase activity, transferring glycosyl groups
BN424_3073	COG1970	mechanosensitive ion channel activity
BN424_3076	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BN424_3078	COG2814	Major facilitator Superfamily
BN424_3090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BN424_3091	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BN424_3092	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BN424_3093	COG1120	ATPase activity
BN424_3096	COG1733	regulation of RNA biosynthetic process
BN424_3097	COG4335	DNA alkylation repair
BN424_3098	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN424_3099	COG4948	Mandelate Racemase Muconate Lactonizing
BN424_31	COG3493	citrate carrier protein
BN424_3100	COG0596	Alpha beta hydrolase
BN424_3101	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BN424_3102	COG1169	isochorismate synthase
BN424_3104	COG0383	alpha-mannosidase activity
BN424_3105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_3105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3106	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3107	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3107	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_3107	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3109	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3110	COG3944	biosynthesis protein
BN424_3111	COG0489	protein tyrosine kinase activity
BN424_3112	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3113	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3114	COG1447	Phosphotransferase system cellobiose-specific component IIA
BN424_3116	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BN424_3116	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BN424_3117	COG0584	glycerophosphoryl diester phosphodiesterase
BN424_3118	COG0584	glycerophosphoryl diester phosphodiesterase
BN424_3119	COG1653	transport
BN424_3121	COG1175	transmembrane transport
BN424_3122	COG3842	ATPase activity
BN424_3123	COG2814	Major facilitator Superfamily
BN424_3124	COG0383	alpha-mannosidase activity
BN424_3125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3126	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3127	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_3127	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3127	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BN424_3128	COG3711	transcriptional antiterminator
BN424_3129	COG1486	melibiose metabolic process
BN424_3130	COG0778	Nitroreductase
BN424_3131	COG1733	regulation of RNA biosynthetic process
BN424_3133	COG2176	DNA-directed DNA polymerase activity
BN424_3134	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BN424_3135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BN424_3136	COG0802	atpase or kinase
BN424_3139	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BN424_314	COG2814	Major facilitator Superfamily
BN424_3140	COG2827	Endonuclease containing a URI domain
BN424_3141	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BN424_3143	COG1119	ATPase activity
BN424_315	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BN424_3150	COG2315	Protein conserved in bacteria
BN424_3152	COG2217	Heavy metal translocating P-type atpase
BN424_3153	COG2608	mercury ion transmembrane transporter activity
BN424_3156	COG2365	Tyrosine phosphatase family
BN424_3160	COG0475	glutathione-regulated potassium exporter activity
BN424_3162	COG3397	chitin binding
BN424_3166	COG3328	transposase activity
BN424_3168	COG1705	Flagellar rod assembly protein muramidase FlgJ
BN424_3170	COG5002	protein histidine kinase activity
BN424_3175	COG0753	catalase activity
BN424_3176	COG0561	phosphatase activity
BN424_3179	COG0183	Belongs to the thiolase family
BN424_318	COG0756	dUTP diphosphatase activity
BN424_3180	COG3425	synthase
BN424_3181	COG5001	Diguanylate cyclase
BN424_3181	COG3300	MHYT domain
BN424_3182	COG5001	Diguanylate cyclase
BN424_3182	COG3300	MHYT domain
BN424_3185	COG1215	transferase activity, transferring glycosyl groups
BN424_319	COG3328	transposase activity
BN424_3191	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3192	COG0803	Belongs to the bacterial solute-binding protein 9 family
BN424_3193	COG1121	(ABC) transporter
BN424_3197	COG1801	Protein of unknown function DUF72
BN424_3198	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3199	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3201	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BN424_3203	COG0745	RESPONSE REGULATOR receiver
BN424_3204	COG5002	protein histidine kinase activity
BN424_3206	COG0708	Exodeoxyribonuclease III
BN424_3207	COG0590	tRNA wobble adenosine to inosine editing
BN424_3208	COG4466	Protein conserved in bacteria
BN424_3209	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BN424_3211	COG0084	hydrolase, TatD family'
BN424_3212	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN424_3212	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN424_3215	COG0318	PFAM AMP-dependent synthetase and ligase
BN424_3216	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BN424_3217	COG2050	protein possibly involved in aromatic compounds catabolism
BN424_3218	COG0589	response to stress
BN424_3228	COG1268	BioY protein
BN424_3233	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BN424_3236	COG0561	phosphatase activity
BN424_3237	COG4716	Myosin-crossreactive antigen
BN424_3239	COG0217	transcriptional regulatory protein
BN424_3242	COG2910	NAD(P)H-binding
BN424_3243	COG1959	2 iron, 2 sulfur cluster binding
BN424_3246	COG2723	6-phospho-beta-galactosidase activity
BN424_3247	COG1447	Phosphotransferase system cellobiose-specific component IIA
BN424_3248	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3251	COG4467	Involved in initiation control of chromosome replication
BN424_3252	COG1774	PSP1 C-terminal conserved region
BN424_3253	COG0470	DNA polymerase III
BN424_3254	COG3870	Protein conserved in bacteria
BN424_3257	COG1846	Transcriptional regulator
BN424_3261	COG1982	Orn Lys Arg decarboxylase major
BN424_3263	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BN424_3264	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BN424_3265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BN424_3272	COG3158	transport of potassium into the cell
BN424_3276	COG0584	glycerophosphoryl diester phosphodiesterase
BN424_333	COG3584	3D domain protein
BN424_3334	COG0582	viral genome integration into host DNA
BN424_3335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BN424_3336	COG0590	tRNA wobble adenosine to inosine editing
BN424_3337	COG2508	Transcriptional regulator
BN424_3339	COG0542	response to heat
BN424_334	COG3706	GGDEF domain
BN424_3340	COG4463	regulation of RNA biosynthetic process
BN424_335	COG3328	transposase activity
BN424_3360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_3361	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BN424_3362	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BN424_3363	COG1780	Probably involved in ribonucleotide reductase function
BN424_337	COG1253	flavin adenine dinucleotide binding
BN424_3372	COG1216	Glycosyl transferase, family 2
BN424_3373	COG0562	UDP-galactopyranose mutase
BN424_3376	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BN424_3378	COG1472	Belongs to the glycosyl hydrolase 3 family
BN424_338	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BN424_3392	COG4932	domain protein
BN424_3392	COG4886	Leucine-rich repeat (LRR) protein
BN424_340	COG2169	Transcriptional regulator
BN424_3402	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BN424_3404	COG0101	tRNA pseudouridine synthase activity
BN424_3406	COG1122	ATPase activity
BN424_3407	COG1122	ATPase activity
BN424_341	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BN424_3411	COG0203	ribosomal protein L17
BN424_3412	COG0202	RNA polymerase activity
BN424_3413	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BN424_3414	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BN424_3416	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BN424_3417	COG0563	adenylate kinase activity
BN424_3419	COG0200	Binds to the 23S rRNA
BN424_3420	COG1841	ribosomal large subunit assembly
BN424_3421	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BN424_3422	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BN424_3423	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BN424_3424	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BN424_3425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BN424_3426	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BN424_3428	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BN424_3429	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BN424_3431	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BN424_3432	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BN424_3433	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BN424_3434	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BN424_3435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BN424_3436	COG0089	rRNA binding
BN424_3437	COG0088	Forms part of the polypeptide exit tunnel
BN424_3438	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BN424_3439	COG0051	transcription antitermination factor activity, RNA binding
BN424_344	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BN424_3440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BN424_3442	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BN424_3443	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BN424_3444	COG0049	tRNA binding
BN424_3445	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BN424_3446	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BN424_3447	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BN424_345	COG0076	glutamate decarboxylase activity
BN424_3450	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BN424_3455	COG2813	Specifically methylates the guanine in position
BN424_3457	COG1028	Short-chain dehydrogenase reductase Sdr
BN424_3458	COG0656	L-ascorbic acid biosynthetic process
BN424_3459	COG1733	regulation of RNA biosynthetic process
BN424_3460	COG1609	Transcriptional regulator
BN424_3462	COG0222	ribosome binding
BN424_3463	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BN424_3464	COG0081	regulation of translation
BN424_3465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BN424_3467	COG0250	Participates in transcription elongation, termination and antitermination
BN424_3468	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BN424_3469	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BN424_347	COG0531	amino acid
BN424_3472	COG4939	FMN-binding domain protein
BN424_3476	COG0142	geranyltranstransferase activity
BN424_3479	COG3328	transposase activity
BN424_3481	COG3688	RNA-binding protein containing a PIN domain
BN424_3482	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN424_3483	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BN424_3484	COG0215	cysteine-tRNA ligase activity
BN424_3486	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BN424_3489	COG4956	integral membrane protein (PIN domain superfamily)
BN424_349	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BN424_3490	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BN424_3492	COG0386	Belongs to the glutathione peroxidase family
BN424_3493	COG1136	(ABC) transporter
BN424_3494	COG0577	efflux transmembrane transporter activity
BN424_3495	COG1309	transcriptional regulator
BN424_3496	COG0402	S-adenosylhomocysteine deaminase activity
BN424_3497	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BN424_3499	COG3842	ATPase activity
BN424_35	COG0702	epimerase
BN424_350	COG1511	domain protein
BN424_3501	COG1176	ABC-type spermidine putrescine transport system, permease component I
BN424_3502	COG5002	protein histidine kinase activity
BN424_3503	COG0745	RESPONSE REGULATOR receiver
BN424_3504	COG0577	efflux transmembrane transporter activity
BN424_3505	COG1136	(ABC) transporter
BN424_3509	COG0778	Nitroreductase
BN424_3510	COG2190	(PTS) system
BN424_3510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_3510	COG1263	PTS System
BN424_3511	COG2723	6-phospho-beta-galactosidase activity
BN424_3512	COG0110	maltose O-acetyltransferase activity
BN424_3514	COG2329	Antibiotic biosynthesis monooxygenase
BN424_3517	COG0012	GTP binding
BN424_3518	COG4481	Protein conserved in bacteria
BN424_3519	COG1475	DNA binding
BN424_352	COG0628	permease
BN424_3520	COG1192	Involved in chromosome partitioning
BN424_3522	COG0357	Ribosomal RNA small subunit methyltransferase G
BN424_3523	COG3541	Predicted nucleotidyltransferase
BN424_3524	COG2807	transmembrane transport
BN424_3529	COG0737	Belongs to the 5'-nucleotidase family
BN424_353	COG0154	amidase activity
BN424_3532	COG3316	Transposase and inactivated derivatives
BN424_3534	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN424_3535	COG2310	stress, protein
BN424_3536	COG2310	stress, protein
BN424_3537	COG2310	stress, protein
BN424_3539	COG3853	Toxic anion resistance protein (TelA)
BN424_3548	COG0454	-acetyltransferase
BN424_3548	COG0456	acetyltransferase
BN424_3549	COG5646	InterPro IPR014922
BN424_3559	COG3328	transposase activity
BN424_3565	COG1902	pentaerythritol trinitrate reductase activity
BN424_3567	COG1309	transcriptional regulator
BN424_3568	COG1621	beta-fructofuranosidase activity
BN424_3569	COG1653	transport
BN424_357	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BN424_3570	COG0395	ABC-type sugar transport system, permease component
BN424_3571	COG4209	transmembrane transport
BN424_3573	COG1609	Transcriptional regulator
BN424_3576	COG0445	tRNA wobble uridine modification
BN424_3577	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BN424_3588	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BN424_3593	COG2188	Transcriptional regulator
BN424_3595	COG4716	Myosin-crossreactive antigen
BN424_3596	COG0076	glutamate decarboxylase activity
BN424_3597	COG1511	domain protein
BN424_3598	COG0531	amino acid
BN424_3599	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BN424_36	COG1902	pentaerythritol trinitrate reductase activity
BN424_360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BN424_3600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BN424_3601	COG0066	3-isopropylmalate dehydratase activity
BN424_3602	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BN424_3603	COG0473	3-isopropylmalate dehydrogenase activity
BN424_3604	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BN424_3605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BN424_3606	COG0440	acetolactate synthase activity
BN424_3607	COG0028	Belongs to the TPP enzyme family
BN424_3608	COG0129	dihydroxy-acid dehydratase activity
BN424_3611	COG0366	Alpha amylase catalytic
BN424_3612	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_3612	COG1263	PTS System
BN424_3617	COG0318	PFAM AMP-dependent synthetase and ligase
BN424_362	COG0251	oxidation-reduction process
BN424_3622	COG4152	abc transporter atp-binding protein
BN424_3625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BN424_3626	COG2376	Dihydroxyacetone kinase
BN424_3629	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BN424_363	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BN424_3630	COG1461	Dihydroxyacetone kinase
BN424_3631	COG2376	Dihydroxyacetone kinase
BN424_3635	COG3443	Belongs to the bacterial solute-binding protein 9 family
BN424_3636	COG0546	phosphoglycolate phosphatase activity
BN424_3637	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BN424_364	COG1263	PTS System
BN424_364	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_365	COG1737	Transcriptional regulator
BN424_3654	COG2267	carboxylic ester hydrolase activity
BN424_3657	COG0706	membrane insertase activity
BN424_3659	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BN424_368	COG5294	Protein conserved in bacteria
BN424_369	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BN424_371	COG1461	Dihydroxyacetone kinase
BN424_374	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BN424_381	COG4720	Psort location CytoplasmicMembrane, score
BN424_382	COG1122	ATPase activity
BN424_388	COG3842	ATPase activity
BN424_389	COG1176	ABC-type spermidine putrescine transport system, permease component I
BN424_390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BN424_393	COG2962	Rard protein
BN424_394	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BN424_395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BN424_398	COG0657	acetylesterase activity
BN424_4	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BN424_404	COG0765	amino acid transport
BN424_405	COG1126	abc transporter atp-binding protein
BN424_406	COG0803	Belongs to the bacterial solute-binding protein 9 family
BN424_406	COG3443	Belongs to the bacterial solute-binding protein 9 family
BN424_407	COG1121	(ABC) transporter
BN424_408	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN424_409	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BN424_41	COG3290	protein histidine kinase activity
BN424_413	COG1175	transmembrane transport
BN424_414	COG0395	ABC-type sugar transport system, permease component
BN424_415	COG1472	Belongs to the glycosyl hydrolase 3 family
BN424_416	COG3459	Glycosyltransferase 36 associated
BN424_417	COG1609	Transcriptional regulator
BN424_419	COG3397	chitin binding
BN424_42	COG4565	transcriptional regulatory protein
BN424_430	COG2096	Adenosyltransferase
BN424_433	COG4810	utilization protein
BN424_436	COG4819	ethanolamine utilization protein
BN424_437	COG4303	Ethanolamine ammonia lyase large subunit
BN424_438	COG4302	ethanolamine ammonia-lyase activity
BN424_439	COG4816	utilization protein
BN424_44	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BN424_441	COG1012	belongs to the aldehyde dehydrogenase family
BN424_441	COG1454	alcohol dehydrogenase
BN424_442	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BN424_444	COG4869	propanediol catabolic process
BN424_446	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BN424_447	COG3192	ethanolamine utilization protein
BN424_448	COG4766	ethanolamine catabolic process
BN424_450	COG0673	inositol 2-dehydrogenase activity
BN424_452	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BN424_453	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BN424_454	COG4166	transmembrane transport
BN424_456	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN424_458	COG0583	DNA-binding transcription factor activity
BN424_460	COG0402	S-adenosylhomocysteine deaminase activity
BN424_462	COG0039	L-malate dehydrogenase activity
BN424_463	COG0193	aminoacyl-tRNA hydrolase activity
BN424_464	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BN424_465	COG2244	polysaccharide biosynthetic process
BN424_466	COG3956	TIGRFAM MazG family protein
BN424_467	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BN424_469	COG1098	S1 RNA binding domain
BN424_470	COG0037	tRNA processing
BN424_471	COG0037	tRNA processing
BN424_471	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BN424_473	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BN424_474	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BN424_475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BN424_476	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BN424_48	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN424_488	COG0038	chloride channel
BN424_489	COG2207	Transcriptional regulator
BN424_489	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BN424_490	COG1132	(ABC) transporter
BN424_491	COG1132	(ABC) transporter
BN424_493	COG1278	Cold shock
BN424_496	COG3961	Belongs to the TPP enzyme family
BN424_5	COG0187	DNA topoisomerase II activity
BN424_50	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BN424_500	COG1609	Transcriptional regulator
BN424_501	COG1263	PTS System
BN424_501	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_503	COG1621	beta-fructofuranosidase activity
BN424_505	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BN424_509	COG0488	(ABC) transporter
BN424_51	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BN424_511	COG0737	Belongs to the 5'-nucleotidase family
BN424_515	COG1840	ABC-type Fe3 transport system, periplasmic component
BN424_516	COG3842	ATPase activity
BN424_518	COG2972	Histidine kinase
BN424_520	COG0531	amino acid
BN424_522	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN424_523	COG0765	amino acid transport
BN424_524	COG1609	Transcriptional regulator
BN424_525	COG1114	Component of the transport system for branched-chain amino acids
BN424_526	COG0789	Transcriptional regulator
BN424_527	COG0431	NADPH-dependent FMN reductase
BN424_531	COG1132	(ABC) transporter
BN424_535	COG3584	3D domain protein
BN424_535	COG3583	domain protein
BN424_537	COG0686	Belongs to the AlaDH PNT family
BN424_538	COG2723	6-phospho-beta-galactosidase activity
BN424_539	COG5564	TIM-barrel signal transduction protein
BN424_54	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BN424_541	COG5564	TIM-barrel signal transduction protein
BN424_543	COG1609	Transcriptional regulator
BN424_544	COG0322	excinuclease ABC activity
BN424_546	COG1126	abc transporter atp-binding protein
BN424_547	COG0765	amino acid transport
BN424_548	COG1309	transcriptional regulator
BN424_55	COG1854	S-ribosylhomocysteine lyase activity
BN424_551	COG2226	methyltransferase
BN424_552	COG0351	phosphomethylpyrimidine kinase
BN424_553	COG0561	phosphatase activity
BN424_554	COG2186	Transcriptional regulator
BN424_555	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BN424_557	COG2610	gluconate transmembrane transporter activity
BN424_558	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BN424_559	COG0280	phosphate acetyltransferase
BN424_564	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BN424_57	COG0626	cystathionine gamma-synthase activity
BN424_570	COG3443	Belongs to the bacterial solute-binding protein 9 family
BN424_570	COG0803	Belongs to the bacterial solute-binding protein 9 family
BN424_571	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BN424_572	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BN424_575	COG0586	Pfam SNARE associated Golgi protein
BN424_577	COG3764	Sortase (surface protein transpeptidase)
BN424_579	COG0783	Belongs to the Dps family
BN424_58	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BN424_580	COG1704	LemA family
BN424_581	COG0501	Belongs to the peptidase M48B family
BN424_583	COG2076	Multidrug Resistance protein
BN424_584	COG2076	Multidrug Resistance protein
BN424_585	COG1181	Belongs to the D-alanine--D-alanine ligase family
BN424_587	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BN424_588	COG0670	Belongs to the BI1 family
BN424_590	COG0736	holo-[acyl-carrier-protein] synthase activity
BN424_591	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BN424_595	COG2337	Toxic component of a toxin-antitoxin (TA) module
BN424_596	COG4708	membrane
BN424_608	COG2388	GCN5-related N-acetyl-transferase
BN424_609	COG0531	amino acid
BN424_61	COG1694	Mazg nucleotide pyrophosphohydrolase
BN424_613	COG1473	amidohydrolase
BN424_614	COG2723	6-phospho-beta-galactosidase activity
BN424_615	COG0039	L-malate dehydrogenase activity
BN424_623	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BN424_624	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BN424_626	COG3706	GGDEF domain
BN424_628	COG1121	(ABC) transporter
BN424_63	COG1064	alcohol dehydrogenase
BN424_630	COG0577	efflux transmembrane transporter activity
BN424_631	COG1136	(ABC) transporter
BN424_632	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BN424_635	COG2183	response to ionizing radiation
BN424_637	COG3091	SprT-like family
BN424_639	COG0681	Belongs to the peptidase S26 family
BN424_64	COG2190	(PTS) system
BN424_641	COG1649	PFAM Uncharacterised BCR, COG1649
BN424_642	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BN424_644	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_646	COG2971	BadF BadG BcrA BcrD
BN424_649	COG1447	Phosphotransferase system cellobiose-specific component IIA
BN424_65	COG3711	transcriptional antiterminator
BN424_651	COG1737	Transcriptional regulator
BN424_654	COG0583	DNA-binding transcription factor activity
BN424_656	COG0584	glycerophosphoryl diester phosphodiesterase
BN424_657	COG1132	(ABC) transporter
BN424_658	COG1132	(ABC) transporter
BN424_660	COG1705	Flagellar rod assembly protein muramidase FlgJ
BN424_661	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BN424_663	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BN424_664	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BN424_665	COG2205	protein histidine kinase activity
BN424_666	COG0745	RESPONSE REGULATOR receiver
BN424_667	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BN424_668	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BN424_669	COG1959	2 iron, 2 sulfur cluster binding
BN424_67	COG0745	RESPONSE REGULATOR receiver
BN424_670	COG1511	domain protein
BN424_673	COG2814	Major facilitator Superfamily
BN424_675	COG0346	lactoylglutathione lyase activity
BN424_680	COG0527	aspartate kinase activity
BN424_686	COG2217	Heavy metal translocating P-type atpase
BN424_688	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BN424_689	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_689	COG1263	PTS System
BN424_690	COG0076	glutamate decarboxylase activity
BN424_691	COG1968	undecaprenyl-diphosphatase activity
BN424_694	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN424_695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN424_696	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN424_699	COG2207	Transcriptional regulator
BN424_7	COG0360	Binds together with S18 to 16S ribosomal RNA
BN424_700	COG0673	inositol 2-dehydrogenase activity
BN424_701	COG0456	acetyltransferase
BN424_705	COG0673	inositol 2-dehydrogenase activity
BN424_71	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BN424_715	COG1737	Transcriptional regulator
BN424_716	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BN424_717	COG2723	6-phospho-beta-galactosidase activity
BN424_72	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BN424_720	COG0673	inositol 2-dehydrogenase activity
BN424_721	COG1263	PTS System
BN424_721	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_722	COG1486	melibiose metabolic process
BN424_723	COG1737	Transcriptional regulator
BN424_725	COG2190	(PTS) system
BN424_725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_725	COG1263	PTS System
BN424_726	COG1011	Hydrolase
BN424_727	COG5434	Belongs to the glycosyl hydrolase 28 family
BN424_733	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BN424_735	COG1368	sulfuric ester hydrolase activity
BN424_736	COG2270	Major facilitator Superfamily
BN424_737	COG1690	Belongs to the RtcB family
BN424_738	COG0778	Nitroreductase
BN424_739	COG3328	transposase activity
BN424_74	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BN424_744	COG3279	Response regulator of the LytR AlgR family
BN424_749	COG2076	Multidrug Resistance protein
BN424_750	COG2076	Multidrug Resistance protein
BN424_751	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN424_752	COG1132	(ABC) transporter
BN424_755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BN424_756	COG0400	carboxylic ester hydrolase activity
BN424_757	COG0346	lactoylglutathione lyase activity
BN424_758	COG0346	lactoylglutathione lyase activity
BN424_759	COG2706	6-phosphogluconolactonase activity
BN424_760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BN424_763	COG0628	permease
BN424_764	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BN424_767	COG1132	(ABC) transporter
BN424_769	COG4808	Protein conserved in bacteria
BN424_770	COG2514	catechol 2,3-dioxygenase activity
BN424_771	COG0024	Methionine aminopeptidase
BN424_772	COG0039	L-malate dehydrogenase activity
BN424_776	COG1482	cell wall glycoprotein biosynthetic process
BN424_777	COG1686	Belongs to the peptidase S11 family
BN424_778	COG3442	glutamine amidotransferase
BN424_779	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BN424_781	COG1435	thymidine kinase activity
BN424_782	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BN424_783	COG2890	protein-(glutamine-N5) methyltransferase activity
BN424_784	COG0009	L-threonylcarbamoyladenylate synthase
BN424_785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BN424_786	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BN424_787	COG0356	it plays a direct role in the translocation of protons across the membrane
BN424_788	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BN424_789	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BN424_790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BN424_791	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BN424_792	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BN424_793	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BN424_794	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BN424_795	COG4836	Membrane
BN424_797	COG1077	Cell shape determining protein MreB Mrl
BN424_799	COG0629	single-stranded DNA binding
BN424_8	COG0629	single-stranded DNA binding
BN424_800	COG1388	LysM domain
BN424_800	COG3584	3D domain protein
BN424_801	COG0745	RESPONSE REGULATOR receiver
BN424_802	COG5002	protein histidine kinase activity
BN424_802	COG3850	Histidine kinase
BN424_805	COG1368	sulfuric ester hydrolase activity
BN424_808	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BN424_809	COG0577	efflux transmembrane transporter activity
BN424_810	COG1136	(ABC) transporter
BN424_811	COG3684	Belongs to the aldolase LacD family
BN424_812	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BN424_815	COG2081	HI0933 family
BN424_816	COG4975	Glucose uptake
BN424_817	COG0531	amino acid
BN424_820	COG1136	(ABC) transporter
BN424_821	COG0577	efflux transmembrane transporter activity
BN424_822	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BN424_824	COG2268	Band 7 protein
BN424_827	COG4129	membrane
BN424_829	COG0559	Belongs to the binding-protein-dependent transport system permease family
BN424_831	COG0411	ABC transporter
BN424_832	COG0410	ABC transporter
BN424_838	COG0628	permease
BN424_840	COG1876	peptidase activity
BN424_842	COG1705	Flagellar rod assembly protein muramidase FlgJ
BN424_844	COG0768	penicillin binding
BN424_846	COG2188	Transcriptional regulator
BN424_847	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BN424_848	COG2233	PERMEase
BN424_851	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BN424_852	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BN424_853	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BN424_854	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BN424_855	COG1301	dicarboxylic acid transport
BN424_858	COG2223	nitrite transmembrane transporter activity
BN424_859	COG2070	2-Nitropropane dioxygenase
BN424_866	COG3739	integral membrane protein
BN424_869	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BN424_870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BN424_873	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BN424_875	COG0557	exoribonuclease II activity
BN424_876	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BN424_877	COG2723	6-phospho-beta-galactosidase activity
BN424_879	COG3279	Response regulator of the LytR AlgR family
BN424_880	COG0772	Belongs to the SEDS family
BN424_881	COG0772	Belongs to the SEDS family
BN424_884	COG3328	transposase activity
BN424_887	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN424_887	COG3711	transcriptional antiterminator
BN424_888	COG2188	Transcriptional regulator
BN424_890	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BN424_893	COG1271	oxidase subunit
BN424_894	COG1294	oxidase, subunit
BN424_895	COG4988	ABC transporter
BN424_896	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BN424_898	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BN424_9	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BN424_905	COG0142	geranyltranstransferase activity
BN424_908	COG1252	NADH dehydrogenase
BN424_910	COG0588	phosphoglycerate mutase activity
BN424_913	COG0583	DNA-binding transcription factor activity
BN424_914	COG0110	maltose O-acetyltransferase activity
BN424_916	COG4221	oxidoreductase activity
BN424_918	COG0667	Aldo Keto reductase
BN424_92	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BN424_920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BN424_921	COG0789	Transcriptional regulator
BN424_922	COG1737	Transcriptional regulator
BN424_923	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_923	COG1263	PTS System
BN424_923	COG2190	(PTS) system
BN424_924	COG2723	6-phospho-beta-galactosidase activity
BN424_927	COG3328	transposase activity
BN424_929	COG0488	(ABC) transporter
BN424_938	COG4989	oxidoreductase activity
BN424_942	COG0686	Belongs to the AlaDH PNT family
BN424_944	COG1295	ribonuclease BN
BN424_948	COG0772	Belongs to the SEDS family
BN424_949	COG1393	Belongs to the ArsC family
BN424_951	COG0509	glycine decarboxylation via glycine cleavage system
BN424_952	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BN424_953	COG2011	ABC-type metal ion transport system permease component
BN424_954	COG1464	Belongs to the NlpA lipoprotein family
BN424_955	COG3279	Response regulator of the LytR AlgR family
BN424_958	COG0346	lactoylglutathione lyase activity
BN424_962	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BN424_963	COG0396	ATPase activity
BN424_964	COG0719	Fe-S assembly protein
BN424_965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BN424_967	COG0719	Fe-S assembly protein
BN424_972	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN424_973	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN424_975	COG3711	transcriptional antiterminator
BN424_976	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BN424_976	COG2190	(PTS) system
BN424_976	COG1263	PTS System
BN424_977	COG2723	6-phospho-beta-galactosidase activity
BN424_978	COG2188	Transcriptional regulator
BN424_98	COG2020	methyltransferase activity
BN424_983	COG3716	PTS system mannose fructose sorbose family IID component
BN424_985	COG0454	-acetyltransferase
BN424_990	COG0346	lactoylglutathione lyase activity
BN424_991	COG0561	phosphatase activity
BN424_993	COG2169	Transcriptional regulator
BN424_997	COG0431	NADPH-dependent FMN reductase