locus-tag	class	description
Chro_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Chro_0002	COG3937	granule-associated protein
Chro_0003	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Chro_0006	COG0800	Aldolase
Chro_0013	COG0730	response to heat
Chro_0015	COG0835	chemotaxis
Chro_0019	COG2201	protein-glutamate methylesterase activity
Chro_0021	COG0316	Belongs to the HesB IscA family
Chro_0027	COG1131	(ABC) transporter
Chro_0028	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Chro_0028	COG0758	DNA mediated transformation
Chro_0032	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_0036	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Chro_0037	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Chro_0037	COG1918	ferrous iron import across plasma membrane
Chro_0041	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Chro_0041	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Chro_0045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Chro_0048	COG2003	Belongs to the UPF0758 family
Chro_0049	COG0572	uridine kinase
Chro_0055	COG0456	acetyltransferase
Chro_0058	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Chro_0059	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_0064	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Chro_0066	COG4999	Histidine kinase
Chro_0066	COG3850	Histidine kinase
Chro_0066	COG2205	protein histidine kinase activity
Chro_0066	COG3437	response regulator, receiver
Chro_0068	COG0481	GTPase activity
Chro_0073	COG1598	PFAM Uncharacterised protein family UPF0150
Chro_0076	COG3842	ATPase activity
Chro_0077	COG1132	(ABC) transporter
Chro_0083	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_0084	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_0085	COG2197	response regulator
Chro_0088	COG0667	Aldo Keto reductase
Chro_0091	COG0003	Pfam Anion-transporting ATPase
Chro_0092	COG0592	DNA-directed DNA polymerase activity
Chro_0093	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Chro_0097	COG2205	protein histidine kinase activity
Chro_0098	COG0745	RESPONSE REGULATOR receiver
Chro_0099	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Chro_0100	COG1819	glycosyl
Chro_0101	COG1132	(ABC) transporter
Chro_0105	COG1216	Glycosyl transferase, family 2
Chro_0105	COG0438	transferase activity, transferring glycosyl groups
Chro_0107	COG1070	Carbohydrate kinase
Chro_0112	COG0625	glutathione transferase activity
Chro_0114	COG3239	Fatty acid desaturase
Chro_0115	COG1247	-acetyltransferase
Chro_0118	COG0579	oxidoreductase
Chro_0120	COG0840	transmembrane signaling receptor activity
Chro_0122	COG0745	RESPONSE REGULATOR receiver
Chro_0125	COG0037	tRNA processing
Chro_0126	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Chro_0128	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Chro_0129	COG0581	inorganic phosphate transmembrane transporter activity
Chro_0130	COG0573	inorganic phosphate transmembrane transporter activity
Chro_0131	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Chro_0140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Chro_0141	COG1136	(ABC) transporter
Chro_0141	COG0577	efflux transmembrane transporter activity
Chro_0142	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Chro_0144	COG1136	(ABC) transporter
Chro_0153	COG0463	Glycosyl transferase, family 2
Chro_0154	COG1104	cysteine desulfurase activity
Chro_0157	COG1381	Involved in DNA repair and RecF pathway recombination
Chro_0159	COG0438	transferase activity, transferring glycosyl groups
Chro_0161	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Chro_0162	COG0488	(ABC) transporter
Chro_0167	COG0254	rRNA binding
Chro_0170	COG0101	tRNA pseudouridine synthase activity
Chro_0177	COG0563	adenylate kinase activity
Chro_0178	COG0201	protein transport
Chro_0179	COG0200	Binds to the 23S rRNA
Chro_0181	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Chro_0183	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Chro_0184	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Chro_0185	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Chro_0186	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Chro_0189	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Chro_0190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Chro_0193	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Chro_0194	COG0089	rRNA binding
Chro_0195	COG0088	Forms part of the polypeptide exit tunnel
Chro_0199	COG3854	ATPases associated with a variety of cellular activities
Chro_0203	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_0205	COG1187	pseudouridine synthase activity
Chro_0207	COG0575	Belongs to the CDS family
Chro_0211	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Chro_0212	COG0339	signal peptide processing
Chro_0214	COG0643	Histidine kinase
Chro_0214	COG0643	Histidine kinase
Chro_0214	COG2198	Histidine kinase
Chro_0214	COG2198	Histidine kinase
Chro_0215	COG0840	transmembrane signaling receptor activity
Chro_0215	COG2203	Gaf domain
Chro_0216	COG0840	transmembrane signaling receptor activity
Chro_0216	COG2203	Gaf domain
Chro_0217	COG0835	chemotaxis
Chro_0219	COG0784	Response regulator, receiver
Chro_0220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Chro_0221	COG0579	oxidoreductase
Chro_0222	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Chro_0224	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Chro_0226	COG4310	Domain of unknown function (DUF2172)
Chro_0227	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_0231	COG0438	transferase activity, transferring glycosyl groups
Chro_0235	COG0463	Glycosyl transferase, family 2
Chro_0242	COG0751	glycine-tRNA ligase activity
Chro_0248	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Chro_0252	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Chro_0253	COG0735	belongs to the Fur family
Chro_0255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_0258	COG0706	membrane insertase activity
Chro_0261	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Chro_0263	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Chro_0264	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Chro_0265	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Chro_0270	COG2084	Dehydrogenase
Chro_0273	COG2205	protein histidine kinase activity
Chro_0273	COG2202	Pas domain
Chro_0275	COG1215	transferase activity, transferring glycosyl groups
Chro_0276	COG3842	ATPase activity
Chro_0277	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Chro_0278	COG0784	Response regulator, receiver
Chro_0279	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Chro_0281	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Chro_0281	COG0140	phosphoribosyl-ATP diphosphatase activity
Chro_0282	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Chro_0285	COG0017	Asparaginyl-tRNA synthetase
Chro_0289	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Chro_0293	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Chro_0296	COG1216	Glycosyl transferase, family 2
Chro_0296	COG0463	Glycosyl transferase, family 2
Chro_0297	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Chro_0300	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_0301	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_0301	COG3321	synthase
Chro_0301	COG0604	alcohol dehydrogenase
Chro_0306	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Chro_0307	COG2226	methyltransferase
Chro_0308	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Chro_0309	COG0569	domain protein
Chro_0310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Chro_0311	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Chro_0311	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Chro_0312	COG1372	Participates in initiation and elongation during chromosome replication
Chro_0312	COG0187	DNA topoisomerase II activity
Chro_0313	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Chro_0317	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Chro_0327	COG1940	carbohydrate kinase activity
Chro_0328	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Chro_0330	COG0483	inositol monophosphate 1-phosphatase activity
Chro_0331	COG1525	nuclease
Chro_0332	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Chro_0333	COG5592	hemerythrin HHE cation binding domain
Chro_0336	COG1872	DUF167
Chro_0344	COG2815	serine threonine protein kinase
Chro_0344	COG0515	serine threonine protein kinase
Chro_0346	COG0494	nUDIX hydrolase
Chro_0347	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Chro_0349	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Chro_0350	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Chro_0353	COG0697	spore germination
Chro_0354	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Chro_0358	COG0330	HflC and HflK could
Chro_0373	COG0515	serine threonine protein kinase
Chro_0375	COG1943	Transposase
Chro_0379	COG0602	queuosine metabolic process
Chro_0380	COG1713	HD superfamily hydrolase involved in NAD metabolism
Chro_0381	COG0799	negative regulation of ribosome biogenesis
Chro_0388	COG0367	asparagine synthase
Chro_0390	COG1794	racemase activity, acting on amino acids and derivatives
Chro_0393	COG2095	MarC family integral membrane protein
Chro_0394	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Chro_0395	COG0058	SHG alpha-glucan phosphorylase activity
Chro_0400	COG0457	Tetratricopeptide repeat
Chro_0400	COG0859	PFAM glycosyl transferase family 9
Chro_0403	COG1121	(ABC) transporter
Chro_0404	COG0803	Belongs to the bacterial solute-binding protein 9 family
Chro_0406	COG3659	wide pore channel activity
Chro_0407	COG0113	porphobilinogen synthase activity
Chro_0412	COG0667	Aldo Keto reductase
Chro_0413	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Chro_0415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Chro_0416	COG5002	protein histidine kinase activity
Chro_0420	COG0393	Putative heavy-metal-binding
Chro_0423	COG2255	four-way junction helicase activity
Chro_0427	COG1131	(ABC) transporter
Chro_0434	COG0473	3-isopropylmalate dehydrogenase activity
Chro_0436	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Chro_0438	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Chro_0441	COG2010	Cytochrome c
Chro_0444	COG0589	response to stress
Chro_0446	COG0268	Binds directly to 16S ribosomal RNA
Chro_0447	COG0084	hydrolase, TatD family'
Chro_0451	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_0452	COG1937	Protein conserved in bacteria
Chro_0453	COG2226	methyltransferase
Chro_0456	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Chro_0458	COG0308	aminopeptidase N
Chro_0465	COG2124	cytochrome p450
Chro_0468	COG0788	formyltetrahydrofolate deformylase activity
Chro_0470	COG3118	belongs to the thioredoxin family
Chro_0471	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_0472	COG0459	protein refolding
Chro_0473	COG0709	Synthesizes selenophosphate from selenide and ATP
Chro_0474	COG0697	spore germination
Chro_0478	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Chro_0488	COG0515	serine threonine protein kinase
Chro_0488	COG3266	domain, Protein
Chro_0490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Chro_0490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Chro_0491	COG2267	carboxylic ester hydrolase activity
Chro_0492	COG1640	4-alpha-glucanotransferase
Chro_0494	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Chro_0494	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Chro_0495	COG0525	valine-tRNA ligase activity
Chro_0496	COG4245	von Willebrand factor, type A
Chro_0497	COG3118	belongs to the thioredoxin family
Chro_0498	COG2095	MarC family integral membrane protein
Chro_0499	COG0328	RNA-DNA hybrid ribonuclease activity
Chro_0505	COG4106	trans-aconitate 2-methyltransferase activity
Chro_0507	COG3266	domain, Protein
Chro_0507	COG0515	serine threonine protein kinase
Chro_0508	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Chro_0512	COG1122	ATPase activity
Chro_0513	COG0357	Ribosomal RNA small subunit methyltransferase G
Chro_0519	COG4989	oxidoreductase activity
Chro_0524	COG5002	protein histidine kinase activity
Chro_0525	COG0531	amino acid
Chro_0526	COG2264	protein methyltransferase activity
Chro_0527	COG2234	aminopeptidase activity
Chro_0528	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_0529	COG0484	heat shock protein binding
Chro_0531	COG0598	Magnesium transport protein CorA
Chro_0534	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Chro_0548	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Chro_0549	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_0552	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Chro_0555	COG4372	Transposase
Chro_0558	COG1160	GTP binding
Chro_0559	COG0668	transmembrane transport
Chro_0562	COG2912	Transglutaminase-like superfamily
Chro_0563	COG2205	protein histidine kinase activity
Chro_0564	COG0745	RESPONSE REGULATOR receiver
Chro_0566	COG1216	Glycosyl transferase, family 2
Chro_0569	COG3659	wide pore channel activity
Chro_0574	COG0432	Pfam Uncharacterised protein family UPF0047
Chro_0575	COG0628	permease
Chro_0577	COG0439	Biotin carboxylase
Chro_0580	COG0277	FAD linked oxidase domain protein
Chro_0580	COG0247	lactate metabolic process
Chro_0581	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Chro_0583	COG0459	protein refolding
Chro_0584	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Chro_0585	COG3411	Ferredoxin
Chro_0587	COG0484	heat shock protein binding
Chro_0590	COG1902	pentaerythritol trinitrate reductase activity
Chro_0591	COG3118	belongs to the thioredoxin family
Chro_0593	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Chro_0595	COG0793	Belongs to the peptidase S41A family
Chro_0597	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Chro_0599	COG0438	transferase activity, transferring glycosyl groups
Chro_0601	COG0297	glycogen (starch) synthase activity
Chro_0602	COG0438	transferase activity, transferring glycosyl groups
Chro_0611	COG0784	Response regulator, receiver
Chro_0611	COG2205	protein histidine kinase activity
Chro_0611	COG5002	protein histidine kinase activity
Chro_0613	COG2198	Histidine kinase
Chro_0613	COG2205	protein histidine kinase activity
Chro_0613	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Chro_0613	COG0784	Response regulator, receiver
Chro_0614	COG2198	Histidine kinase
Chro_0614	COG0643	Histidine kinase
Chro_0615	COG0835	chemotaxis
Chro_0616	COG0840	transmembrane signaling receptor activity
Chro_0617	COG2201	protein-glutamate methylesterase activity
Chro_0618	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Chro_0623	COG0180	Tryptophanyl-tRNA synthetase
Chro_0627	COG0581	inorganic phosphate transmembrane transporter activity
Chro_0628	COG0573	inorganic phosphate transmembrane transporter activity
Chro_0629	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Chro_0632	COG2119	membrane
Chro_0635	COG0589	response to stress
Chro_0639	COG0792	nuclease activity
Chro_0641	COG1064	alcohol dehydrogenase
Chro_0642	COG0358	DNA primase activity
Chro_0643	COG2226	methyltransferase
Chro_0646	COG0142	geranyltranstransferase activity
Chro_0649	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Chro_0650	COG0860	N-Acetylmuramoyl-L-alanine amidase
Chro_0651	COG0475	glutathione-regulated potassium exporter activity
Chro_0653	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Chro_0655	COG1172	Belongs to the binding-protein-dependent transport system permease family
Chro_0656	COG4191	Histidine kinase
Chro_0656	COG2205	protein histidine kinase activity
Chro_0656	COG0745	RESPONSE REGULATOR receiver
Chro_0657	COG2205	protein histidine kinase activity
Chro_0657	COG2202	Pas domain
Chro_0658	COG1606	tRNA processing
Chro_0662	COG3000	fatty acid hydroxylase
Chro_0662	COG0300	oxidoreductase activity
Chro_0663	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Chro_0667	COG1127	ABC transporter
Chro_0671	COG1233	COG1233 Phytoene dehydrogenase and related
Chro_0681	COG0632	four-way junction helicase activity
Chro_0682	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Chro_0684	COG1940	carbohydrate kinase activity
Chro_0686	COG1858	cytochrome C peroxidase
Chro_0688	COG0416	fatty acid biosynthetic process
Chro_0689	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Chro_0690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Chro_0691	COG0318	PFAM AMP-dependent synthetase and ligase
Chro_0691	COG0204	Acyl-transferase
Chro_0693	COG0628	permease
Chro_0701	COG0110	maltose O-acetyltransferase activity
Chro_0703	COG1132	(ABC) transporter
Chro_0706	COG0110	maltose O-acetyltransferase activity
Chro_0708	COG1215	transferase activity, transferring glycosyl groups
Chro_0710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Chro_0711	COG0318	PFAM AMP-dependent synthetase and ligase
Chro_0712	COG2986	histidine ammonia-lyase
Chro_0717	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Chro_0718	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Chro_0719	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Chro_0720	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Chro_0721	COG0517	IMP dehydrogenase activity
Chro_0721	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Chro_0725	COG1216	Glycosyl transferase, family 2
Chro_0727	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Chro_0733	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Chro_0738	COG1215	transferase activity, transferring glycosyl groups
Chro_0739	COG0438	transferase activity, transferring glycosyl groups
Chro_0749	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Chro_0753	COG1797	cobyrinic acid a,c-diamide synthase activity
Chro_0754	COG3409	Peptidoglycan-binding domain 1 protein
Chro_0754	COG3429	Glucose-6-phosphate dehydrogenase subunit
Chro_0755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Chro_0756	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Chro_0758	COG0724	RNA recognition motif
Chro_0760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Chro_0762	COG1309	transcriptional regulator
Chro_0764	COG0525	valine-tRNA ligase activity
Chro_0767	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Chro_0770	COG0025	NhaP-type Na H and K H
Chro_0771	COG0497	DNA recombination
Chro_0774	COG2197	response regulator
Chro_0778	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Chro_0782	COG0824	Thioesterase
Chro_0783	COG1619	proteins homologs of microcin C7 resistance protein MccF
Chro_0786	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Chro_0792	COG0438	transferase activity, transferring glycosyl groups
Chro_0794	COG0438	transferase activity, transferring glycosyl groups
Chro_0796	COG1215	transferase activity, transferring glycosyl groups
Chro_0797	COG0438	transferase activity, transferring glycosyl groups
Chro_0800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Chro_0801	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_0802	COG0110	maltose O-acetyltransferase activity
Chro_0804	COG0673	inositol 2-dehydrogenase activity
Chro_0810	COG0489	protein tyrosine kinase activity
Chro_0811	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Chro_0812	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Chro_0818	COG2264	protein methyltransferase activity
Chro_0819	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Chro_0821	COG0438	transferase activity, transferring glycosyl groups
Chro_0824	COG0300	oxidoreductase activity
Chro_0825	COG1115	amino acid carrier protein
Chro_0826	COG0589	response to stress
Chro_0828	COG1845	cytochrome c oxidase, subunit III
Chro_0830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Chro_0850	COG1285	pathogenesis
Chro_0852	COG0625	glutathione transferase activity
Chro_0853	COG2124	cytochrome p450
Chro_0854	COG1309	transcriptional regulator
Chro_0855	COG0778	Nitroreductase
Chro_0872	COG4783	chaperone-mediated protein folding
Chro_0874	COG0745	RESPONSE REGULATOR receiver
Chro_0875	COG2205	protein histidine kinase activity
Chro_0877	COG1132	(ABC) transporter
Chro_0879	COG0438	transferase activity, transferring glycosyl groups
Chro_0884	COG1136	(ABC) transporter
Chro_0884	COG0577	efflux transmembrane transporter activity
Chro_0885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Chro_0890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Chro_0893	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Chro_0896	COG1253	flavin adenine dinucleotide binding
Chro_0897	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Chro_0898	COG0673	inositol 2-dehydrogenase activity
Chro_0901	COG3848	Pyruvate phosphate dikinase
Chro_0901	COG0574	Belongs to the PEP-utilizing enzyme family
Chro_0902	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Chro_0903	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Chro_0904	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Chro_0904	COG1116	anion transmembrane transporter activity
Chro_0905	COG1116	anion transmembrane transporter activity
Chro_0906	COG0659	secondary active sulfate transmembrane transporter activity
Chro_0910	COG0651	ATP synthesis coupled electron transport
Chro_0917	COG1803	Methylglyoxal synthase
Chro_0917	COG1597	lipid kinase activity
Chro_0920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Chro_0923	COG0765	amino acid transport
Chro_0924	COG0765	amino acid transport
Chro_0925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Chro_0926	COG1126	abc transporter atp-binding protein
Chro_0927	COG2351	hydroxyisourate hydrolase activity
Chro_0928	COG3195	allantoin biosynthetic process
Chro_0928	COG3648	Uricase
Chro_0929	COG3659	wide pore channel activity
Chro_0932	COG2233	PERMEase
Chro_0933	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Chro_0943	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Chro_0948	COG0625	glutathione transferase activity
Chro_0951	COG0612	Peptidase, M16
Chro_0954	COG0006	proline dipeptidase activity
Chro_0956	COG2239	Acts as a magnesium transporter
Chro_0957	COG0395	ABC-type sugar transport system, permease component
Chro_0961	COG3842	ATPase activity
Chro_0963	COG1802	Transcriptional regulator
Chro_0967	COG0649	NAD binding
Chro_0971	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Chro_0972	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Chro_0974	COG0460	homoserine dehydrogenase
Chro_0975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Chro_0976	COG0572	uridine kinase
Chro_0980	COG0741	lytic transglycosylase activity
Chro_0980	COG1196	nuclear chromosome segregation
Chro_0980	COG0739	heme binding
Chro_0981	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Chro_0981	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Chro_0984	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Chro_0987	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
Chro_0990	COG0516	GMP reductase activity
Chro_0990	COG0517	IMP dehydrogenase activity
Chro_0996	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Chro_0997	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Chro_1000	COG1543	Belongs to the glycosyl hydrolase 57 family
Chro_1003	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
Chro_1004	COG0583	DNA-binding transcription factor activity
Chro_1007	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Chro_1007	COG4451	ribulose bisphosphate carboxylase, small
Chro_1008	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Chro_1009	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Chro_1010	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Chro_1011	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Chro_1012	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_1022	COG2197	response regulator
Chro_1024	COG1858	cytochrome C peroxidase
Chro_1028	COG4251	negative regulation of phosphorylation
Chro_1028	COG5001	Diguanylate cyclase
Chro_1028	COG2203	Gaf domain
Chro_1028	COG3706	GGDEF domain
Chro_1035	COG0237	dephospho-CoA kinase activity
Chro_1035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Chro_1044	COG0681	Belongs to the peptidase S26 family
Chro_1046	COG3266	domain, Protein
Chro_1046	COG0515	serine threonine protein kinase
Chro_1048	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Chro_1051	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Chro_1063	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_1064	COG0189	ligase activity
Chro_1064	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Chro_1070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Chro_1077	COG2124	cytochrome p450
Chro_1081	COG1446	asparaginase
Chro_1082	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Chro_1083	COG2217	Heavy metal translocating P-type atpase
Chro_1086	COG0577	efflux transmembrane transporter activity
Chro_1086	COG1136	(ABC) transporter
Chro_1093	COG0589	response to stress
Chro_1094	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Chro_1099	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
Chro_1106	COG1088	dTDP-glucose 4,6-dehydratase activity
Chro_1108	COG0463	Glycosyl transferase, family 2
Chro_1113	COG1846	Transcriptional regulator
Chro_1114	COG4249	Peptidase C14 caspase catalytic subunit p20
Chro_1114	COG2319	Wd-40 repeat
Chro_1117	COG0667	Aldo Keto reductase
Chro_1118	COG0596	Alpha beta hydrolase
Chro_1119	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Chro_1120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Chro_1125	COG0028	Belongs to the TPP enzyme family
Chro_1129	COG2207	Transcriptional regulator
Chro_1129	COG1917	Cupin 2, conserved barrel domain protein
Chro_1131	COG1899	peptidyl-lysine modification to peptidyl-hypusine
Chro_1132	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Chro_1133	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Chro_1143	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Chro_1159	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Chro_1159	COG0574	Belongs to the PEP-utilizing enzyme family
Chro_1161	COG0484	heat shock protein binding
Chro_1193	COG0489	protein tyrosine kinase activity
Chro_1194	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Chro_1195	COG2226	methyltransferase
Chro_1199	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Chro_1201	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Chro_1204	COG1215	transferase activity, transferring glycosyl groups
Chro_1206	COG0438	transferase activity, transferring glycosyl groups
Chro_1215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Chro_1216	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Chro_1217	COG2133	pyrroloquinoline quinone binding
Chro_1218	COG0154	amidase activity
Chro_1219	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_1222	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Chro_1224	COG0701	Predicted permease
Chro_1227	COG3273	potassium ion transport
Chro_1227	COG0471	metal ion transport
Chro_1229	COG3659	wide pore channel activity
Chro_1237	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Chro_1240	COG4106	trans-aconitate 2-methyltransferase activity
Chro_1244	COG1295	ribonuclease BN
Chro_1244	COG1959	2 iron, 2 sulfur cluster binding
Chro_1248	COG2124	cytochrome p450
Chro_1250	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Chro_1251	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Chro_1253	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Chro_1261	COG0583	DNA-binding transcription factor activity
Chro_1267	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Chro_1269	COG3386	PFAM SMP-30 Gluconolaconase
Chro_1271	COG0784	Response regulator, receiver
Chro_1272	COG2205	protein histidine kinase activity
Chro_1272	COG5002	protein histidine kinase activity
Chro_1272	COG0784	Response regulator, receiver
Chro_1276	COG1215	transferase activity, transferring glycosyl groups
Chro_1286	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Chro_1289	COG0484	heat shock protein binding
Chro_1292	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Chro_1295	COG0371	Dehydrogenase
Chro_1296	COG0436	Aminotransferase
Chro_1306	COG0667	Aldo Keto reductase
Chro_1308	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Chro_1311	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Chro_1316	COG2203	Gaf domain
Chro_1316	COG5001	Diguanylate cyclase
Chro_1316	COG3706	GGDEF domain
Chro_1316	COG4251	negative regulation of phosphorylation
Chro_1319	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Chro_1320	COG1121	(ABC) transporter
Chro_1326	COG4774	siderophore transport
Chro_1329	COG2010	Cytochrome c
Chro_1330	COG0443	Heat shock 70 kDa protein
Chro_1332	COG2890	protein-(glutamine-N5) methyltransferase activity
Chro_1335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Chro_1336	COG0484	heat shock protein binding
Chro_1339	COG2154	pterin-4-alpha-carbinolamine dehydratase
Chro_1340	COG2211	Major facilitator Superfamily
Chro_1341	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Chro_1342	COG0534	Mate efflux family protein
Chro_1344	COG1917	Cupin 2, conserved barrel domain protein
Chro_1344	COG4977	sequence-specific DNA binding
Chro_1353	COG4953	penicillin-binding protein 1C
Chro_1354	COG1176	ABC-type spermidine putrescine transport system, permease component I
Chro_1356	COG3842	ATPase activity
Chro_1357	COG0768	penicillin binding
Chro_1359	COG3228	Belongs to the MtfA family
Chro_1360	COG0784	Response regulator, receiver
Chro_1360	COG5002	protein histidine kinase activity
Chro_1364	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Chro_1365	COG2373	Large extracellular alpha-helical protein
Chro_1371	COG1754	DNA topoisomerase type I activity
Chro_1371	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Chro_1375	COG1215	transferase activity, transferring glycosyl groups
Chro_1376	COG4783	chaperone-mediated protein folding
Chro_1383	COG0450	alkyl hydroperoxide reductase
Chro_1384	COG2319	Wd-40 repeat
Chro_1384	COG4249	Peptidase C14 caspase catalytic subunit p20
Chro_1385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Chro_1387	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Chro_1389	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Chro_1391	COG0494	nUDIX hydrolase
Chro_1392	COG0697	spore germination
Chro_1393	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Chro_1396	COG2129	metallophosphoesterase
Chro_1401	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Chro_1408	COG3063	Type IV pilus biogenesis stability protein PilW
Chro_1409	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Chro_1410	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Chro_1411	COG0135	phosphoribosylanthranilate isomerase activity
Chro_1415	COG1994	Peptidase M50
Chro_1415	COG0517	IMP dehydrogenase activity
Chro_1416	COG3340	Belongs to the peptidase S51 family
Chro_1417	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Chro_1418	COG0859	PFAM glycosyl transferase family 9
Chro_1420	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Chro_1433	COG0745	RESPONSE REGULATOR receiver
Chro_1434	COG5002	protein histidine kinase activity
Chro_1435	COG0704	Plays a role in the regulation of phosphate uptake
Chro_1437	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Chro_1438	COG3659	wide pore channel activity
Chro_1441	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Chro_1443	COG0596	Alpha beta hydrolase
Chro_1444	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Chro_1450	COG0346	lactoylglutathione lyase activity
Chro_1455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Chro_1458	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_1460	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Chro_1463	COG0745	RESPONSE REGULATOR receiver
Chro_1465	COG0022	dehydrogenase e1 component
Chro_1465	COG0508	dehydrogenase complex catalyzes the overall conversion of
Chro_1466	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Chro_1467	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Chro_1474	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Chro_1477	COG0612	Peptidase, M16
Chro_1478	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Chro_1480	COG1950	PFAM Membrane protein of
Chro_1482	COG0300	oxidoreductase activity
Chro_1483	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Chro_1484	COG2081	HI0933 family
Chro_1485	COG0556	nucleotide-excision repair
Chro_1487	COG3237	CsbD-like
Chro_1494	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Chro_1496	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Chro_1497	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Chro_1498	COG0750	zinc metalloprotease
Chro_1504	COG2205	protein histidine kinase activity
Chro_1505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Chro_1508	COG0456	acetyltransferase
Chro_1509	COG3977	Valine--pyruvate aminotransferase
Chro_1514	COG1640	4-alpha-glucanotransferase
Chro_1517	COG0390	transport system, permease component
Chro_1529	COG3659	wide pore channel activity
Chro_1533	COG3483	tryptophan 2,3-dioxygenase activity
Chro_1539	COG0012	GTP binding
Chro_1543	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Chro_1544	COG0745	RESPONSE REGULATOR receiver
Chro_1545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Chro_1546	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Chro_1549	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Chro_1550	COG0302	gtp cyclohydrolase
Chro_1551	COG0300	oxidoreductase activity
Chro_1552	COG0825	malonyl-CoA metabolic process
Chro_1553	COG5322	oxidoreductase activity
Chro_1554	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Chro_1556	COG0395	ABC-type sugar transport system, permease component
Chro_1559	COG2239	Acts as a magnesium transporter
Chro_1561	COG1473	amidohydrolase
Chro_1563	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Chro_1577	COG2202	Pas domain
Chro_1577	COG2205	protein histidine kinase activity
Chro_1580	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Chro_1580	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Chro_1582	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Chro_1584	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Chro_1585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Chro_1586	COG0640	Transcriptional regulator
Chro_1588	COG0740	serine-type endopeptidase activity
Chro_1590	COG1131	(ABC) transporter
Chro_1593	COG0784	Response regulator, receiver
Chro_1594	COG2203	Gaf domain
Chro_1594	COG3706	GGDEF domain
Chro_1594	COG4251	negative regulation of phosphorylation
Chro_1594	COG5001	Diguanylate cyclase
Chro_1595	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Chro_1599	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Chro_1602	COG3706	GGDEF domain
Chro_1602	COG0745	RESPONSE REGULATOR receiver
Chro_1603	COG1304	FMN binding
Chro_1604	COG0616	signal peptide processing
Chro_1605	COG0475	glutathione-regulated potassium exporter activity
Chro_1611	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_1612	COG0114	fumarate hydratase activity
Chro_1615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Chro_1615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Chro_1618	COG1252	NADH dehydrogenase
Chro_1619	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Chro_1623	COG0492	ferredoxin-NADP+ reductase activity
Chro_1624	COG0784	Response regulator, receiver
Chro_1624	COG5002	protein histidine kinase activity
Chro_1627	COG0574	Belongs to the PEP-utilizing enzyme family
Chro_1627	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Chro_1629	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Chro_1631	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Chro_1633	COG1216	Glycosyl transferase, family 2
Chro_1634	COG0586	Pfam SNARE associated Golgi protein
Chro_1636	COG0360	Binds together with S18 to 16S ribosomal RNA
Chro_1640	COG1429	ligase activity, forming nitrogen-metal bonds
Chro_1641	COG1943	Transposase
Chro_1645	COG2131	deaminase
Chro_1648	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Chro_1662	COG1968	undecaprenyl-diphosphatase activity
Chro_1665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Chro_1666	COG4636	protein conserved in cyanobacteria
Chro_1670	COG2197	response regulator
Chro_1680	COG0628	permease
Chro_1681	COG0628	permease
Chro_1683	COG1122	ATPase activity
Chro_1684	COG3688	RNA-binding protein containing a PIN domain
Chro_1689	COG4581	dead DEAH box helicase
Chro_1690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Chro_1691	COG1799	cell septum assembly
Chro_1692	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Chro_1694	COG0736	holo-[acyl-carrier-protein] synthase activity
Chro_1695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Chro_1696	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Chro_1697	COG1160	GTP binding
Chro_1700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_1703	COG0484	heat shock protein binding
Chro_1704	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Chro_1706	COG0010	Belongs to the arginase family
Chro_1707	COG0375	protein maturation
Chro_1710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Chro_1711	COG1116	anion transmembrane transporter activity
Chro_1713	COG0811	peptide transport
Chro_1714	COG0848	biopolymer transport protein
Chro_1716	COG4771	TonB-dependent receptor
Chro_1717	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Chro_1723	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Chro_1724	COG0443	Heat shock 70 kDa protein
Chro_1728	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Chro_1729	COG0189	ligase activity
Chro_1730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Chro_1731	COG1570	exodeoxyribonuclease VII activity
Chro_1733	COG1722	exodeoxyribonuclease VII activity
Chro_1734	COG2066	Belongs to the glutaminase family
Chro_1737	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Chro_1738	COG2048	Heterodisulfide reductase, subunit B
Chro_1739	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Chro_1740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Chro_1741	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Chro_1742	COG1349	DNA-binding transcription factor activity
Chro_1743	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Chro_1744	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Chro_1747	COG0659	secondary active sulfate transmembrane transporter activity
Chro_1749	COG0347	Belongs to the P(II) protein family
Chro_1750	COG0475	glutathione-regulated potassium exporter activity
Chro_1754	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Chro_1755	COG0523	cobalamin synthesis protein
Chro_1762	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Chro_1764	COG2226	methyltransferase
Chro_1772	COG0508	dehydrogenase complex catalyzes the overall conversion of
Chro_1772	COG0596	Alpha beta hydrolase
Chro_1773	COG0628	permease
Chro_1774	COG0850	regulation of cytokinetic process
Chro_1775	COG2894	cell division
Chro_1776	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Chro_1779	COG4178	(ABC) transporter
Chro_1784	COG3546	catalase activity
Chro_1786	COG0673	inositol 2-dehydrogenase activity
Chro_1792	COG0693	protein deglycase activity
Chro_1795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Chro_1796	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Chro_1799	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Chro_1800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Chro_1801	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Chro_1802	COG0544	peptidyl-prolyl cis-trans isomerase activity
Chro_1803	COG0740	serine-type endopeptidase activity
Chro_1806	COG0778	Nitroreductase
Chro_1807	COG1725	Transcriptional regulator
Chro_1808	COG0412	Dienelactone hydrolase
Chro_1809	COG0539	negative regulation of cytoplasmic translation
Chro_1812	COG1175	transmembrane transport
Chro_1813	COG1653	transport
Chro_1814	COG2610	gluconate transmembrane transporter activity
Chro_1815	COG4636	protein conserved in cyanobacteria
Chro_1819	COG3659	wide pore channel activity
Chro_1822	COG2052	Domain of unknown function (DUF370)
Chro_1828	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Chro_1830	COG0306	phosphate transporter
Chro_1832	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_1833	COG3259	Nickel-dependent hydrogenase
Chro_1835	COG0375	protein maturation
Chro_1836	COG0384	phenazine biosynthesis protein PhzF
Chro_1847	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Chro_1848	COG0739	heme binding
Chro_1849	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Chro_1850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Chro_1852	COG1172	Belongs to the binding-protein-dependent transport system permease family
Chro_1854	COG1879	ABC-type sugar transport system periplasmic component
Chro_1855	COG1702	phosphate starvation-inducible protein PhoH
Chro_1857	COG0228	four-way junction DNA binding
Chro_1858	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Chro_1865	COG5002	protein histidine kinase activity
Chro_1868	COG0175	sulfate reduction
Chro_1876	COG0747	negative chemotaxis
Chro_1877	COG0747	negative chemotaxis
Chro_1878	COG0747	negative chemotaxis
Chro_1879	COG1691	(AIR) carboxylase
Chro_1880	COG0463	Glycosyl transferase, family 2
Chro_1881	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Chro_1882	COG0745	RESPONSE REGULATOR receiver
Chro_1883	COG0784	Response regulator, receiver
Chro_1883	COG5002	protein histidine kinase activity
Chro_1883	COG2198	Histidine kinase
Chro_1885	COG4191	Histidine kinase
Chro_1885	COG0784	Response regulator, receiver
Chro_1887	COG2091	lysine biosynthetic process via aminoadipic acid
Chro_1899	COG1012	belongs to the aldehyde dehydrogenase family
Chro_1900	COG0745	RESPONSE REGULATOR receiver
Chro_1902	COG0784	Response regulator, receiver
Chro_1904	COG1063	alcohol dehydrogenase
Chro_1905	COG0515	serine threonine protein kinase
Chro_1907	COG1836	PFAM Integral membrane protein DUF92
Chro_1910	COG0346	lactoylglutathione lyase activity
Chro_1913	COG0438	transferase activity, transferring glycosyl groups
Chro_1914	COG0672	)-iron permease
Chro_1917	COG2132	Multicopper oxidase
Chro_1918	COG1122	ATPase activity
Chro_1921	COG0310	cobalt ion transport
Chro_1933	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Chro_1936	COG1619	proteins homologs of microcin C7 resistance protein MccF
Chro_1937	COG0438	transferase activity, transferring glycosyl groups
Chro_1938	COG0697	spore germination
Chro_1939	COG0616	signal peptide processing
Chro_1941	COG1473	amidohydrolase
Chro_1944	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Chro_1952	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_1953	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_1954	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_1957	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Chro_1958	COG4783	chaperone-mediated protein folding
Chro_1962	COG0726	polysaccharide deacetylase
Chro_1963	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Chro_1964	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Chro_1966	COG3842	ATPase activity
Chro_1967	COG1012	belongs to the aldehyde dehydrogenase family
Chro_1968	COG1177	transmembrane transport
Chro_1969	COG1176	ABC-type spermidine putrescine transport system, permease component I
Chro_1971	COG0352	thiamine-phosphate diphosphorylase activity
Chro_1975	COG0681	Belongs to the peptidase S26 family
Chro_1976	COG1022	Amp-dependent synthetase and ligase
Chro_1978	COG0508	dehydrogenase complex catalyzes the overall conversion of
Chro_1981	COG0745	RESPONSE REGULATOR receiver
Chro_1991	COG0601	transmembrane transport
Chro_1999	COG4245	von Willebrand factor, type A
Chro_2000	COG0784	Response regulator, receiver
Chro_2003	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Chro_2004	COG0719	Fe-S assembly protein
Chro_2005	COG0396	ATPase activity
Chro_2006	COG0719	Fe-S assembly protein
Chro_2012	COG0697	spore germination
Chro_2015	COG1132	(ABC) transporter
Chro_2016	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Chro_2017	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Chro_2019	COG3150	esterase
Chro_2033	COG2319	Wd-40 repeat
Chro_2033	COG4249	Peptidase C14 caspase catalytic subunit p20
Chro_2034	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Chro_2037	COG0723	plastoquinol--plastocyanin reductase activity
Chro_2040	COG1295	ribonuclease BN
Chro_2041	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Chro_2045	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Chro_2048	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Chro_2049	COG0745	RESPONSE REGULATOR receiver
Chro_2052	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Chro_2056	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Chro_2057	COG0463	Glycosyl transferase, family 2
Chro_2057	COG0457	Tetratricopeptide repeat
Chro_2065	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Chro_2066	COG0196	riboflavin kinase activity
Chro_2070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Chro_2074	COG1230	cation diffusion facilitator family transporter
Chro_2077	COG0542	response to heat
Chro_2078	COG5002	protein histidine kinase activity
Chro_2080	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_2083	COG0443	Heat shock 70 kDa protein
Chro_2084	COG4689	acetoacetate decarboxylase
Chro_2085	COG0745	RESPONSE REGULATOR receiver
Chro_2087	COG0557	exoribonuclease II activity
Chro_2088	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Chro_2090	COG0303	'Molybdopterin
Chro_2095	COG0628	permease
Chro_2099	COG1489	DNA binding
Chro_2103	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Chro_2109	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Chro_2112	COG2226	methyltransferase
Chro_2114	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Chro_2121	COG0745	RESPONSE REGULATOR receiver
Chro_2121	COG3706	GGDEF domain
Chro_2125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Chro_2128	COG1215	transferase activity, transferring glycosyl groups
Chro_2130	COG0438	transferase activity, transferring glycosyl groups
Chro_2131	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Chro_2133	COG3206	protein involved in exopolysaccharide biosynthesis
Chro_2133	COG0489	protein tyrosine kinase activity
Chro_2149	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Chro_2154	COG1215	transferase activity, transferring glycosyl groups
Chro_2155	COG2244	polysaccharide biosynthetic process
Chro_2159	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Chro_2160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Chro_2161	COG3608	succinylglutamate desuccinylase aspartoacylase
Chro_2161	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Chro_2164	COG4221	oxidoreductase activity
Chro_2172	COG1640	4-alpha-glucanotransferase
Chro_2173	COG3386	PFAM SMP-30 Gluconolaconase
Chro_2175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Chro_2181	COG0492	ferredoxin-NADP+ reductase activity
Chro_2182	COG5002	protein histidine kinase activity
Chro_2187	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Chro_2188	COG0640	Transcriptional regulator
Chro_2189	COG3835	regulator
Chro_2190	COG0438	transferase activity, transferring glycosyl groups
Chro_2191	COG0859	PFAM glycosyl transferase family 9
Chro_2194	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Chro_2195	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_2197	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Chro_2197	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Chro_2200	COG0859	PFAM glycosyl transferase family 9
Chro_2202	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Chro_2203	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Chro_2220	COG5002	protein histidine kinase activity
Chro_2221	COG0284	orotidine-5'-phosphate decarboxylase activity
Chro_2221	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Chro_2226	COG0646	methionine synthase
Chro_2226	COG1410	methionine synthase
Chro_2231	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Chro_2232	COG0789	Transcriptional regulator
Chro_2243	COG0489	protein tyrosine kinase activity
Chro_2244	COG0515	serine threonine protein kinase
Chro_2244	COG1357	PFAM Pentapeptide repeats (8 copies)
Chro_2250	COG0713	ATP synthesis coupled electron transport
Chro_2251	COG0839	Belongs to the complex I subunit 6 family
Chro_2254	COG0372	Belongs to the citrate synthase family
Chro_2255	COG2062	phosphohistidine phosphatase, SixA
Chro_2259	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Chro_2260	COG0438	transferase activity, transferring glycosyl groups
Chro_2265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Chro_2266	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Chro_2267	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Chro_2268	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Chro_2269	COG1649	PFAM Uncharacterised BCR, COG1649
Chro_2269	COG0726	polysaccharide deacetylase
Chro_2270	COG4245	von Willebrand factor, type A
Chro_2271	COG4279	zinc finger
Chro_2272	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Chro_2281	COG4968	Prepilin-type N-terminal cleavage methylation domain
Chro_2287	COG0438	transferase activity, transferring glycosyl groups
Chro_2289	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Chro_2292	COG3609	addiction module antidote protein, CC2985 family
Chro_2295	COG0515	serine threonine protein kinase
Chro_2295	COG1357	PFAM Pentapeptide repeats (8 copies)
Chro_2299	COG0438	transferase activity, transferring glycosyl groups
Chro_2300	COG0489	protein tyrosine kinase activity
Chro_2303	COG2198	Histidine kinase
Chro_2303	COG0643	Histidine kinase
Chro_2304	COG0840	transmembrane signaling receptor activity
Chro_2304	COG2203	Gaf domain
Chro_2317	COG2267	carboxylic ester hydrolase activity
Chro_2321	COG0552	protein localization to endoplasmic reticulum
Chro_2322	COG2208	phosphoserine phosphatase activity
Chro_2326	COG0440	acetolactate synthase activity
Chro_2328	COG2267	carboxylic ester hydrolase activity
Chro_2331	COG0697	spore germination
Chro_2333	COG1803	Methylglyoxal synthase
Chro_2333	COG1597	lipid kinase activity
Chro_2341	COG1049	propionate catabolic process, 2-methylcitrate cycle
Chro_2342	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Chro_2344	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Chro_2346	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Chro_2347	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Chro_2350	COG1132	(ABC) transporter
Chro_2352	COG0463	Glycosyl transferase, family 2
Chro_2355	COG1136	(ABC) transporter
Chro_2355	COG0577	efflux transmembrane transporter activity
Chro_2356	COG2326	polyphosphate kinase activity
Chro_2358	COG1309	transcriptional regulator
Chro_2362	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Chro_2363	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Chro_2364	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_2367	COG3206	protein involved in exopolysaccharide biosynthesis
Chro_2367	COG0489	protein tyrosine kinase activity
Chro_2372	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Chro_2374	COG1215	transferase activity, transferring glycosyl groups
Chro_2377	COG1215	transferase activity, transferring glycosyl groups
Chro_2378	COG0438	transferase activity, transferring glycosyl groups
Chro_2379	COG0438	transferase activity, transferring glycosyl groups
Chro_2381	COG1215	transferase activity, transferring glycosyl groups
Chro_2384	COG0438	transferase activity, transferring glycosyl groups
Chro_2387	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Chro_2394	COG0737	Belongs to the 5'-nucleotidase family
Chro_2397	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Chro_2398	COG1309	transcriptional regulator
Chro_2399	COG0596	Alpha beta hydrolase
Chro_2406	COG3240	lipase activity
Chro_2412	COG3706	GGDEF domain
Chro_2412	COG2203	Gaf domain
Chro_2412	COG4251	negative regulation of phosphorylation
Chro_2412	COG5001	Diguanylate cyclase
Chro_2413	COG0784	Response regulator, receiver
Chro_2415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Chro_2415	COG0045	succinate-CoA ligase (ADP-forming) activity
Chro_2415	COG1042	CoA-binding domain protein
Chro_2416	COG0583	DNA-binding transcription factor activity
Chro_2423	COG0678	peroxiredoxin activity
Chro_2423	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Chro_2426	COG1125	glycine betaine transport
Chro_2426	COG0517	IMP dehydrogenase activity
Chro_2427	COG1174	glycine betaine transport
Chro_2428	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Chro_2429	COG0745	RESPONSE REGULATOR receiver
Chro_2431	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Chro_2439	COG1193	negative regulation of DNA recombination
Chro_2440	COG0516	GMP reductase activity
Chro_2441	COG3118	belongs to the thioredoxin family
Chro_2451	COG4774	siderophore transport
Chro_2456	COG2124	cytochrome p450
Chro_2460	COG0438	transferase activity, transferring glycosyl groups
Chro_2467	COG0438	transferase activity, transferring glycosyl groups
Chro_2468	COG1132	(ABC) transporter
Chro_2471	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Chro_2472	COG0646	methionine synthase
Chro_2472	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Chro_2476	COG0517	IMP dehydrogenase activity
Chro_2476	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Chro_2477	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Chro_2479	COG1442	glycosyl transferase family 8
Chro_2480	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Chro_2481	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Chro_2484	COG1216	Glycosyl transferase, family 2
Chro_2492	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Chro_2499	COG0724	RNA recognition motif
Chro_2503	COG1032	radical SAM domain protein
Chro_2507	COG0724	RNA recognition motif
Chro_2510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Chro_2512	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Chro_2520	COG0535	radical SAM domain protein
Chro_2522	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Chro_2523	COG0251	oxidation-reduction process
Chro_2529	COG0463	Glycosyl transferase, family 2
Chro_2532	COG2885	chlorophyll binding
Chro_2534	COG1615	UPF0182 protein
Chro_2536	COG2204	response regulator
Chro_2540	COG0643	Histidine kinase
Chro_2540	COG2198	Histidine kinase
Chro_2541	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Chro_2544	COG0023	Translation Initiation Factor
Chro_2547	COG0123	including yeast histone deacetylase and acetoin utilization protein
Chro_2548	COG0435	Glutathione S-transferase
Chro_2549	COG1132	(ABC) transporter
Chro_2556	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Chro_2568	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Chro_2572	COG1191	sigma factor activity
Chro_2573	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Chro_2586	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Chro_2592	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Chro_2594	COG0693	protein deglycase activity
Chro_2595	COG0419	ATPase involved in DNA repair
Chro_2598	COG0330	HflC and HflK could
Chro_2600	COG3266	domain, Protein
Chro_2600	COG0515	serine threonine protein kinase
Chro_2604	COG0045	succinate-CoA ligase (ADP-forming) activity
Chro_2605	COG0300	oxidoreductase activity
Chro_2606	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Chro_2610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Chro_2613	COG0277	FAD linked oxidase domain protein
Chro_2614	COG0247	lactate metabolic process
Chro_2618	COG0589	response to stress
Chro_2619	COG1271	oxidase subunit
Chro_2621	COG0668	transmembrane transport
Chro_2622	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Chro_2623	COG0586	Pfam SNARE associated Golgi protein
Chro_2624	COG1132	(ABC) transporter
Chro_2628	COG2010	Cytochrome c
Chro_2630	COG0742	ribosomal rna small subunit methyltransferase
Chro_2632	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Chro_2636	COG0456	acetyltransferase
Chro_2638	COG2223	nitrite transmembrane transporter activity
Chro_2639	COG0673	inositol 2-dehydrogenase activity
Chro_2640	COG1357	PFAM Pentapeptide repeats (8 copies)
Chro_2640	COG0515	serine threonine protein kinase
Chro_2641	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Chro_2645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Chro_2648	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Chro_2650	COG0123	including yeast histone deacetylase and acetoin utilization protein
Chro_2652	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Chro_2653	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Chro_2657	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Chro_2662	COG0424	maF-like protein
Chro_2682	COG1309	transcriptional regulator
Chro_2684	COG4948	Mandelate Racemase Muconate Lactonizing
Chro_2690	COG5002	protein histidine kinase activity
Chro_2694	COG0456	acetyltransferase
Chro_2696	COG0137	argininosuccinate synthase activity
Chro_2697	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Chro_2702	COG0740	serine-type endopeptidase activity
Chro_2703	COG2304	oxidoreductase activity
Chro_2706	COG1309	transcriptional regulator
Chro_2716	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Chro_2717	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Chro_2718	COG1116	anion transmembrane transporter activity
Chro_2718	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Chro_2722	COG0686	Belongs to the AlaDH PNT family
Chro_2724	COG1051	belongs to the nudix hydrolase family
Chro_2732	COG4325	translation initiation factor activity
Chro_2733	COG0589	response to stress
Chro_2733	COG0475	glutathione-regulated potassium exporter activity
Chro_2735	COG0475	glutathione-regulated potassium exporter activity
Chro_2738	COG2201	protein-glutamate methylesterase activity
Chro_2739	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Chro_2744	COG1596	polysaccharide export
Chro_2745	COG0131	Imidazoleglycerol-phosphate dehydratase
Chro_2746	COG0668	transmembrane transport
Chro_2747	COG2211	Major facilitator Superfamily
Chro_2748	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Chro_2750	COG3266	domain, Protein
Chro_2750	COG0515	serine threonine protein kinase
Chro_2751	COG0222	ribosome binding
Chro_2753	COG0081	regulation of translation
Chro_2755	COG0250	Participates in transcription elongation, termination and antitermination
Chro_2756	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Chro_2757	COG0335	large ribosomal subunit rRNA binding
Chro_2759	COG3239	Fatty acid desaturase
Chro_2760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Chro_2760	COG0426	domain, Protein
Chro_2763	COG0426	domain, Protein
Chro_2763	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Chro_2768	COG4636	protein conserved in cyanobacteria
Chro_2769	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Chro_2771	COG4221	oxidoreductase activity
Chro_2773	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Chro_2779	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Chro_2781	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Chro_2783	COG3437	response regulator, receiver
Chro_2785	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Chro_2786	COG0148	phosphopyruvate hydratase activity
Chro_2788	COG0542	response to heat
Chro_2791	COG0463	Glycosyl transferase, family 2
Chro_2791	COG1216	Glycosyl transferase, family 2
Chro_2792	COG2244	polysaccharide biosynthetic process
Chro_2793	COG1442	glycosyl transferase family 8
Chro_2793	COG1216	Glycosyl transferase, family 2
Chro_2796	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Chro_2796	COG2273	Hydrolase Family 16
Chro_2797	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Chro_2797	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Chro_2798	COG0438	transferase activity, transferring glycosyl groups
Chro_2799	COG0438	transferase activity, transferring glycosyl groups
Chro_2800	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Chro_2803	COG1846	Transcriptional regulator
Chro_2805	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Chro_2806	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Chro_2807	COG0288	reversible hydration of carbon dioxide
Chro_2808	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Chro_2809	COG0583	DNA-binding transcription factor activity
Chro_2810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Chro_2812	COG0584	glycerophosphoryl diester phosphodiesterase
Chro_2813	COG5002	protein histidine kinase activity
Chro_2825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Chro_2827	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Chro_2829	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Chro_2832	COG0351	phosphomethylpyrimidine kinase
Chro_2834	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Chro_2842	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Chro_2845	COG0640	Transcriptional regulator
Chro_2846	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Chro_2847	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Chro_2850	COG0798	PFAM Bile acid sodium symporter
Chro_2851	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Chro_2852	COG0640	Transcriptional regulator
Chro_2853	COG2226	methyltransferase
Chro_2859	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Chro_2860	COG4956	integral membrane protein (PIN domain superfamily)
Chro_2862	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Chro_2864	COG0438	transferase activity, transferring glycosyl groups
Chro_2866	COG1063	alcohol dehydrogenase
Chro_2870	COG0783	Belongs to the Dps family
Chro_2872	COG2385	sporulation resulting in formation of a cellular spore
Chro_2875	COG0312	modulator of DNA gyrase
Chro_2880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Chro_2891	COG0405	Gamma-glutamyltransferase
Chro_2892	COG2319	Wd-40 repeat
Chro_2892	COG3903	Transcriptional regulator
Chro_2902	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Chro_2903	COG2226	methyltransferase
Chro_2904	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Chro_2907	COG2226	methyltransferase
Chro_2911	COG1960	acyl-CoA dehydrogenase activity
Chro_2912	COG0183	Belongs to the thiolase family
Chro_2913	COG1250	3-hydroxyacyl-CoA dehydrogenase
Chro_2913	COG1024	Enoyl-CoA hydratase
Chro_2915	COG0596	Alpha beta hydrolase
Chro_2918	COG0436	Aminotransferase
Chro_2920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_2921	COG0156	8-amino-7-oxononanoate synthase activity
Chro_2928	COG0235	Class ii aldolase
Chro_2929	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Chro_2930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Chro_2932	COG0438	transferase activity, transferring glycosyl groups
Chro_2935	COG0697	spore germination
Chro_2936	COG0659	secondary active sulfate transmembrane transporter activity
Chro_2939	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Chro_2943	COG0477	Major facilitator Superfamily
Chro_2944	COG1040	competence protein
Chro_2945	COG0805	protein transport
Chro_2949	COG2045	Belongs to the ComB family
Chro_2959	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Chro_2963	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Chro_2965	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Chro_2969	COG0489	protein tyrosine kinase activity
Chro_2971	COG5002	protein histidine kinase activity
Chro_2975	COG0577	efflux transmembrane transporter activity
Chro_2975	COG1136	(ABC) transporter
Chro_2976	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Chro_2977	COG0861	Integral membrane protein TerC family
Chro_2978	COG0105	UTP biosynthetic process
Chro_2979	COG1166	arginine decarboxylase activity
Chro_2980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Chro_2982	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Chro_2984	COG3536	Protein conserved in bacteria
Chro_2985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Chro_2986	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Chro_2987	COG0716	FMN binding
Chro_2991	COG1573	uracil-dna glycosylase
Chro_2993	COG0284	orotidine-5'-phosphate decarboxylase activity
Chro_2994	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Chro_2995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Chro_2996	COG1741	Belongs to the pirin family
Chro_2997	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Chro_2999	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Chro_3001	COG2205	protein histidine kinase activity
Chro_3003	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Chro_3004	COG1253	flavin adenine dinucleotide binding
Chro_3005	COG0297	glycogen (starch) synthase activity
Chro_3006	COG0181	hydroxymethylbilane synthase activity
Chro_3008	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
Chro_3010	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Chro_3016	COG0667	Aldo Keto reductase
Chro_3017	COG4115	mRNA cleavage
Chro_3018	COG2161	toxin-antitoxin pair type II binding
Chro_3019	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Chro_3020	COG1518	maintenance of DNA repeat elements
Chro_3028	COG1959	2 iron, 2 sulfur cluster binding
Chro_3029	COG4251	negative regulation of phosphorylation
Chro_3031	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Chro_3031	COG3264	Mechanosensitive ion channel
Chro_3032	COG5002	protein histidine kinase activity
Chro_3033	COG0745	RESPONSE REGULATOR receiver
Chro_3042	COG0612	Peptidase, M16
Chro_3044	COG2885	chlorophyll binding
Chro_3052	COG0745	RESPONSE REGULATOR receiver
Chro_3053	COG2197	response regulator
Chro_3055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Chro_3057	COG0070	glutamate synthase
Chro_3057	COG0069	glutamate synthase activity
Chro_3057	COG0067	glutamate synthase
Chro_3058	COG0493	'glutamate synthase
Chro_3064	COG4249	Peptidase C14 caspase catalytic subunit p20
Chro_3067	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Chro_3071	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Chro_3072	COG1058	Belongs to the CinA family
Chro_3072	COG1546	Belongs to the CinA family
Chro_3074	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Chro_3076	COG1480	7TM receptor with intracellular HD hydrolase
Chro_3077	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Chro_3082	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_3085	COG0438	transferase activity, transferring glycosyl groups
Chro_3086	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_3087	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Chro_3088	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Chro_3091	COG0312	modulator of DNA gyrase
Chro_3093	COG1917	Cupin 2, conserved barrel domain protein
Chro_3093	COG4977	sequence-specific DNA binding
Chro_3094	COG0793	Belongs to the peptidase S41A family
Chro_3095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Chro_3095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Chro_3096	COG0745	RESPONSE REGULATOR receiver
Chro_3098	COG0346	lactoylglutathione lyase activity
Chro_3100	COG2154	pterin-4-alpha-carbinolamine dehydratase
Chro_3103	COG1609	Transcriptional regulator
Chro_3105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Chro_3115	COG2304	oxidoreductase activity
Chro_3125	COG0287	Prephenate dehydrogenase
Chro_3125	COG1605	Chorismate mutase
Chro_3127	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Chro_3129	COG0625	glutathione transferase activity
Chro_3133	COG1216	Glycosyl transferase, family 2
Chro_3140	COG0512	Glutamine amidotransferase of anthranilate synthase
Chro_3140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Chro_3142	COG0159	tryptophan synthase activity
Chro_3144	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Chro_3145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Chro_3150	COG0243	molybdopterin cofactor binding
Chro_3153	COG0596	Alpha beta hydrolase
Chro_3153	COG0508	dehydrogenase complex catalyzes the overall conversion of
Chro_3157	COG1598	PFAM Uncharacterised protein family UPF0150
Chro_3158	COG3046	protein related to deoxyribodipyrimidine photolyase
Chro_3160	COG0442	prolyl-tRNA aminoacylation
Chro_3161	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Chro_3161	COG0574	Belongs to the PEP-utilizing enzyme family
Chro_3164	COG2183	response to ionizing radiation
Chro_3167	COG0454	-acetyltransferase
Chro_3168	COG0156	8-amino-7-oxononanoate synthase activity
Chro_3172	COG5002	protein histidine kinase activity
Chro_3174	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Chro_3176	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Chro_3177	COG2205	protein histidine kinase activity
Chro_3182	COG0501	Belongs to the peptidase M48B family
Chro_3186	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Chro_3190	COG4251	negative regulation of phosphorylation
Chro_3199	COG1429	ligase activity, forming nitrogen-metal bonds
Chro_3203	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Chro_3203	COG1017	nitric oxide dioxygenase activity
Chro_3205	COG0469	pyruvate kinase activity
Chro_3209	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Chro_3213	COG4585	Histidine kinase
Chro_3215	COG1136	(ABC) transporter
Chro_3215	COG0577	efflux transmembrane transporter activity
Chro_3218	COG3268	Saccharopine dehydrogenase
Chro_3219	COG0515	serine threonine protein kinase
Chro_3219	COG1357	PFAM Pentapeptide repeats (8 copies)
Chro_3221	COG0300	oxidoreductase activity
Chro_3230	COG4251	negative regulation of phosphorylation
Chro_3231	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_3242	COG3706	GGDEF domain
Chro_3242	COG0745	RESPONSE REGULATOR receiver
Chro_3243	COG2203	Gaf domain
Chro_3243	COG5001	Diguanylate cyclase
Chro_3243	COG3706	GGDEF domain
Chro_3243	COG4251	negative regulation of phosphorylation
Chro_3246	COG1475	DNA binding
Chro_3264	COG3437	response regulator, receiver
Chro_3265	COG2205	protein histidine kinase activity
Chro_3265	COG2198	Histidine kinase
Chro_3265	COG0784	Response regulator, receiver
Chro_3266	COG1653	transport
Chro_3270	COG1672	PFAM Archaeal ATPase
Chro_3270	COG2319	Wd-40 repeat
Chro_3273	COG1840	ABC-type Fe3 transport system, periplasmic component
Chro_3274	COG3128	pkhd-type hydroxylase
Chro_3276	COG1178	ABC-type Fe3 transport system permease component
Chro_3277	COG3842	ATPase activity
Chro_3283	COG1215	transferase activity, transferring glycosyl groups
Chro_3286	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_3287	COG2329	Antibiotic biosynthesis monooxygenase
Chro_3288	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_3297	COG3781	membrane
Chro_3298	COG0288	reversible hydration of carbon dioxide
Chro_3306	COG3903	Transcriptional regulator
Chro_3306	COG2319	Wd-40 repeat
Chro_3307	COG3903	Transcriptional regulator
Chro_3307	COG2319	Wd-40 repeat
Chro_3308	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Chro_3309	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Chro_3313	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Chro_3314	COG5002	protein histidine kinase activity
Chro_3317	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Chro_3322	COG1408	metallophosphoesterase
Chro_3331	COG0745	RESPONSE REGULATOR receiver
Chro_3337	COG0783	Belongs to the Dps family
Chro_3338	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Chro_3340	COG0494	nUDIX hydrolase
Chro_3341	COG2205	protein histidine kinase activity
Chro_3345	COG1472	Belongs to the glycosyl hydrolase 3 family
Chro_3347	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Chro_3348	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Chro_3349	COG4208	sulfate ABC transporter
Chro_3350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Chro_3351	COG4251	negative regulation of phosphorylation
Chro_3352	COG5002	protein histidine kinase activity
Chro_3352	COG0784	Response regulator, receiver
Chro_3353	COG1214	PFAM Peptidase M22, glycoprotease
Chro_3356	COG0336	Belongs to the RNA methyltransferase TrmD family
Chro_3359	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Chro_3360	COG0515	serine threonine protein kinase
Chro_3360	COG3266	domain, Protein
Chro_3361	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Chro_3362	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Chro_3365	COG3256	nitric oxide reductase
Chro_3370	COG0629	single-stranded DNA binding
Chro_3371	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Chro_3373	COG2099	Precorrin-6x reductase
Chro_3380	COG2267	carboxylic ester hydrolase activity
Chro_3385	COG0582	viral genome integration into host DNA
Chro_3386	COG0582	viral genome integration into host DNA
Chro_3394	COG1104	cysteine desulfurase activity
Chro_3399	COG0564	pseudouridine synthase activity
Chro_3405	COG1413	lyase activity
Chro_3409	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Chro_3410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Chro_3411	COG1413	lyase activity
Chro_3412	COG1413	lyase activity
Chro_3413	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Chro_3415	COG0237	dephospho-CoA kinase activity
Chro_3418	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Chro_3419	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Chro_3422	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Chro_3426	COG0006	proline dipeptidase activity
Chro_3433	COG0285	dihydrofolate synthase activity
Chro_3439	COG4636	protein conserved in cyanobacteria
Chro_3444	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Chro_3445	COG0840	transmembrane signaling receptor activity
Chro_3445	COG2203	Gaf domain
Chro_3446	COG0546	phosphoglycolate phosphatase activity
Chro_3447	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Chro_3448	COG3631	Ketosteroid isomerase-related protein
Chro_3451	COG2197	response regulator
Chro_3453	COG4251	negative regulation of phosphorylation
Chro_3454	COG0745	RESPONSE REGULATOR receiver
Chro_3455	COG0784	Response regulator, receiver
Chro_3455	COG2205	protein histidine kinase activity
Chro_3459	COG0069	glutamate synthase activity
Chro_3459	COG0070	glutamate synthase
Chro_3459	COG0067	glutamate synthase
Chro_3462	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Chro_3463	COG0745	RESPONSE REGULATOR receiver
Chro_3465	COG0542	response to heat
Chro_3466	COG2203	Gaf domain
Chro_3466	COG0840	transmembrane signaling receptor activity
Chro_3467	COG0577	efflux transmembrane transporter activity
Chro_3467	COG1136	(ABC) transporter
Chro_3471	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Chro_3472	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Chro_3475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Chro_3479	COG1177	transmembrane transport
Chro_3480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Chro_3483	COG2207	Transcriptional regulator
Chro_3483	COG0662	Cupin 2, conserved barrel domain protein
Chro_3488	COG0483	inositol monophosphate 1-phosphatase activity
Chro_3489	COG2211	Major facilitator Superfamily
Chro_3490	COG0667	Aldo Keto reductase
Chro_3491	COG0513	Belongs to the DEAD box helicase family
Chro_3492	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Chro_3493	COG0434	BtpA family
Chro_3494	COG4243	Vitamin k epoxide reductase
Chro_3497	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Chro_3508	COG2205	protein histidine kinase activity
Chro_3510	COG4251	negative regulation of phosphorylation
Chro_3511	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Chro_3513	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Chro_3513	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Chro_3517	COG0559	Belongs to the binding-protein-dependent transport system permease family
Chro_3519	COG0411	ABC transporter
Chro_3520	COG0410	ABC transporter
Chro_3522	COG1216	Glycosyl transferase, family 2
Chro_3522	COG0463	Glycosyl transferase, family 2
Chro_3523	COG2226	methyltransferase
Chro_3526	COG0438	transferase activity, transferring glycosyl groups
Chro_3527	COG0297	glycogen (starch) synthase activity
Chro_3533	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Chro_3544	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Chro_3545	COG0667	Aldo Keto reductase
Chro_3550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Chro_3551	COG0724	RNA recognition motif
Chro_3552	COG1132	(ABC) transporter
Chro_3557	COG2308	Evidence 4 Homologs of previously reported genes of
Chro_3559	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Chro_3562	COG0033	Phosphoglucomutase
Chro_3564	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Chro_3569	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Chro_3570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Chro_3571	COG1116	anion transmembrane transporter activity
Chro_3571	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Chro_3572	COG1116	anion transmembrane transporter activity
Chro_3573	COG2223	nitrite transmembrane transporter activity
Chro_3574	COG0243	molybdopterin cofactor binding
Chro_3576	COG0457	Tetratricopeptide repeat
Chro_3577	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Chro_3578	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Chro_3579	COG0435	Glutathione S-transferase
Chro_3580	COG1690	Belongs to the RtcB family
Chro_3583	COG1940	carbohydrate kinase activity
Chro_3585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Chro_3592	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Chro_3604	COG5002	protein histidine kinase activity
Chro_3608	COG0745	RESPONSE REGULATOR receiver
Chro_3618	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Chro_3620	COG2207	Transcriptional regulator
Chro_3623	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Chro_3624	COG2207	Transcriptional regulator
Chro_3624	COG1609	Transcriptional regulator
Chro_3627	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Chro_3629	COG1132	(ABC) transporter
Chro_3632	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Chro_3635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Chro_3636	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Chro_3637	COG1120	ATPase activity
Chro_3645	COG1132	(ABC) transporter
Chro_3646	COG1132	(ABC) transporter
Chro_3647	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Chro_3648	COG4771	TonB-dependent receptor
Chro_3651	COG0736	holo-[acyl-carrier-protein] synthase activity
Chro_3652	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Chro_3653	COG1169	isochorismate synthase
Chro_3654	COG0736	holo-[acyl-carrier-protein] synthase activity
Chro_3655	COG1045	serine acetyltransferase
Chro_3656	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Chro_3661	COG2226	methyltransferase
Chro_3661	COG3433	isochorismatase activity
Chro_3661	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Chro_3673	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Chro_3673	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Chro_3673	COG3321	synthase
Chro_3673	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_3673	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_3676	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Chro_3683	COG2832	Protein of unknown function (DUF454)
Chro_3687	COG2217	Heavy metal translocating P-type atpase
Chro_3695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Chro_3697	COG2832	Protein of unknown function (DUF454)
Chro_3701	COG2217	Heavy metal translocating P-type atpase
Chro_3704	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Chro_3705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Chro_3707	COG4607	ABC-type enterochelin transport system periplasmic component
Chro_3713	COG1132	(ABC) transporter
Chro_3714	COG1132	(ABC) transporter
Chro_3717	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Chro_3753	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Chro_3768	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Chro_3769	COG2161	toxin-antitoxin pair type II binding
Chro_3770	COG4115	mRNA cleavage
Chro_3775	COG2361	Protein of unknown function DUF86
Chro_3782	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Chro_3788	COG2166	iron-sulfur cluster assembly
Chro_3789	COG0523	cobalamin synthesis protein
Chro_3790	COG0302	gtp cyclohydrolase
Chro_3791	COG0523	cobalamin synthesis protein
Chro_3804	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Chro_3813	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Chro_3827	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Chro_3830	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Chro_3833	COG2205	protein histidine kinase activity
Chro_3833	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Chro_3835	COG0745	RESPONSE REGULATOR receiver
Chro_3836	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_3838	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Chro_3843	COG4783	chaperone-mediated protein folding
Chro_3849	COG1408	metallophosphoesterase
Chro_3857	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Chro_3861	COG0668	transmembrane transport
Chro_3862	COG4325	translation initiation factor activity
Chro_3869	COG0116	Belongs to the methyltransferase superfamily
Chro_3873	COG2124	cytochrome p450
Chro_3881	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Chro_3890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Chro_3899	COG0470	DNA polymerase III
Chro_3906	COG2267	carboxylic ester hydrolase activity
Chro_3907	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_3908	COG0251	oxidation-reduction process
Chro_3915	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_3918	COG1733	regulation of RNA biosynthetic process
Chro_3921	COG2197	response regulator
Chro_3922	COG0515	serine threonine protein kinase
Chro_3922	COG2815	serine threonine protein kinase
Chro_3925	COG4221	oxidoreductase activity
Chro_3927	COG2207	Transcriptional regulator
Chro_3941	COG0631	protein serine/threonine phosphatase activity
Chro_3942	COG0515	serine threonine protein kinase
Chro_3942	COG2815	serine threonine protein kinase
Chro_3954	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Chro_3955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Chro_3957	COG0556	nucleotide-excision repair
Chro_3958	COG0429	hydrolase of the alpha beta-hydrolase fold
Chro_3959	COG0745	RESPONSE REGULATOR receiver
Chro_3960	COG0644	oxidoreductase
Chro_3963	COG0640	Transcriptional regulator
Chro_3964	COG0511	ligase activity, forming carbon-carbon bonds
Chro_3965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Chro_3967	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Chro_3970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_3971	COG1196	nuclear chromosome segregation
Chro_3971	COG0741	lytic transglycosylase activity
Chro_3971	COG0739	heme binding
Chro_3973	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Chro_3977	COG0475	glutathione-regulated potassium exporter activity
Chro_3977	COG0589	response to stress
Chro_3978	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_3979	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Chro_3981	COG0724	RNA recognition motif
Chro_3985	COG0714	Associated with various cellular activities
Chro_3991	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_3995	COG1357	PFAM Pentapeptide repeats (8 copies)
Chro_3995	COG0515	serine threonine protein kinase
Chro_3999	COG5398	heme oxygenase
Chro_4000	COG2135	peptidase activity
Chro_4002	COG3659	wide pore channel activity
Chro_4003	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_4004	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_4006	COG0515	serine threonine protein kinase
Chro_4008	COG0515	serine threonine protein kinase
Chro_4009	COG0842	Transport permease protein
Chro_4009	COG1131	(ABC) transporter
Chro_4009	COG1716	ATPase activity
Chro_4014	COG0415	Belongs to the DNA photolyase family
Chro_4015	COG0151	Belongs to the GarS family
Chro_4016	COG5002	protein histidine kinase activity
Chro_4017	COG1247	-acetyltransferase
Chro_4025	COG0305	Participates in initiation and elongation during chromosome replication
Chro_4025	COG1372	Participates in initiation and elongation during chromosome replication
Chro_4025	COG1372	Participates in initiation and elongation during chromosome replication
Chro_4025	COG0305	Participates in initiation and elongation during chromosome replication
Chro_4026	COG0359	binds to the 23S rRNA
Chro_4028	COG0537	adenosine 5'-monophosphoramidase activity
Chro_4029	COG0606	chelatase, subunit chli
Chro_4030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Chro_4030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Chro_4033	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Chro_4036	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Chro_4037	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Chro_4039	COG2385	sporulation resulting in formation of a cellular spore
Chro_4043	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Chro_4049	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Chro_4050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Chro_4051	COG1845	cytochrome c oxidase, subunit III
Chro_4053	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Chro_4054	COG0776	regulation of translation
Chro_4060	COG1131	(ABC) transporter
Chro_4061	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Chro_4061	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Chro_4065	COG1077	Cell shape determining protein MreB Mrl
Chro_4066	COG0629	single-stranded DNA binding
Chro_4069	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Chro_4070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Chro_4071	COG1285	pathogenesis
Chro_4077	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Chro_4086	COG1575	Belongs to the MenA family. Type 1 subfamily
Chro_4088	COG0318	PFAM AMP-dependent synthetase and ligase
Chro_4089	COG0824	Thioesterase
Chro_4091	COG0723	plastoquinol--plastocyanin reductase activity
Chro_4093	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Chro_4096	COG2223	nitrite transmembrane transporter activity
Chro_4100	COG1131	(ABC) transporter
Chro_4104	COG0653	protein targeting
Chro_4108	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Chro_4111	COG1309	transcriptional regulator
Chro_4112	COG0571	ribonuclease III activity
Chro_4113	COG0596	Alpha beta hydrolase
Chro_4115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Chro_4116	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Chro_4117	COG1253	flavin adenine dinucleotide binding
Chro_4126	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Chro_4127	COG0793	Belongs to the peptidase S41A family
Chro_4130	COG1131	(ABC) transporter
Chro_4133	COG0617	tRNA 3'-terminal CCA addition
Chro_4138	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Chro_4140	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Chro_4146	COG0784	Response regulator, receiver
Chro_4146	COG2205	protein histidine kinase activity
Chro_4151	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Chro_4156	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Chro_4158	COG0521	Mo-molybdopterin cofactor biosynthetic process
Chro_4160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_4163	COG0515	serine threonine protein kinase
Chro_4164	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Chro_4168	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Chro_4170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_4174	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Chro_4179	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Chro_4183	COG0129	dihydroxy-acid dehydratase activity
Chro_4186	COG1175	transmembrane transport
Chro_4188	COG3659	wide pore channel activity
Chro_4190	COG0277	FAD linked oxidase domain protein
Chro_4192	COG1196	nuclear chromosome segregation
Chro_4194	COG5002	protein histidine kinase activity
Chro_4198	COG3781	membrane
Chro_4200	COG0784	Response regulator, receiver
Chro_4204	COG0840	transmembrane signaling receptor activity
Chro_4204	COG2203	Gaf domain
Chro_4208	COG4999	Histidine kinase
Chro_4208	COG3437	response regulator, receiver
Chro_4208	COG2205	protein histidine kinase activity
Chro_4208	COG3850	Histidine kinase
Chro_4210	COG1666	GTP binding
Chro_4213	COG1695	Transcriptional regulator
Chro_4215	COG0857	belongs to the CobB CobQ family
Chro_4217	COG1185	polyribonucleotide nucleotidyltransferase activity
Chro_4218	COG5001	Diguanylate cyclase
Chro_4219	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Chro_4220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Chro_4221	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Chro_4223	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_4224	COG0515	serine threonine protein kinase
Chro_4224	COG1357	PFAM Pentapeptide repeats (8 copies)
Chro_4225	COG0072	phenylalanine-tRNA ligase activity
Chro_4225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Chro_4226	COG0402	S-adenosylhomocysteine deaminase activity
Chro_4227	COG1131	(ABC) transporter
Chro_4229	COG2205	protein histidine kinase activity
Chro_4229	COG0784	Response regulator, receiver
Chro_4230	COG5001	Diguanylate cyclase
Chro_4230	COG4251	negative regulation of phosphorylation
Chro_4230	COG3706	GGDEF domain
Chro_4230	COG2203	Gaf domain
Chro_4234	COG0343	queuine tRNA-ribosyltransferase activity
Chro_4238	COG0589	response to stress
Chro_4243	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Chro_4246	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Chro_4247	COG0671	phosphoesterase, PA-phosphatase related
Chro_4250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Chro_4253	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Chro_4255	COG0531	amino acid
Chro_4258	COG2239	Acts as a magnesium transporter
Chro_4259	COG1950	PFAM Membrane protein of
Chro_4262	COG0745	RESPONSE REGULATOR receiver
Chro_4264	COG5002	protein histidine kinase activity
Chro_4265	COG0745	RESPONSE REGULATOR receiver
Chro_4270	COG1017	nitric oxide dioxygenase activity
Chro_4270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Chro_4272	COG1950	PFAM Membrane protein of
Chro_4276	COG3932	Exopolysaccharide synthesis, ExoD
Chro_4281	COG0586	Pfam SNARE associated Golgi protein
Chro_4282	COG2340	Cysteine-rich secretory protein family
Chro_4286	COG0628	permease
Chro_4289	COG4783	chaperone-mediated protein folding
Chro_4297	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Chro_4298	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Chro_4299	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Chro_4300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Chro_4302	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Chro_4303	COG0356	it plays a direct role in the translocation of protons across the membrane
Chro_4305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_4319	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Chro_4319	COG0237	dephospho-CoA kinase activity
Chro_4323	COG0772	Belongs to the SEDS family
Chro_4328	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Chro_4337	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Chro_4341	COG0363	glucosamine-6-phosphate deaminase activity
Chro_4342	COG1716	ATPase activity
Chro_4346	COG0746	molybdenum cofactor guanylyltransferase activity
Chro_4347	COG5001	Diguanylate cyclase
Chro_4347	COG5002	protein histidine kinase activity
Chro_4350	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Chro_4352	COG2076	Multidrug Resistance protein
Chro_4353	COG3237	CsbD-like
Chro_4354	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Chro_4359	COG1598	PFAM Uncharacterised protein family UPF0150
Chro_4361	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Chro_4364	COG1160	GTP binding
Chro_4367	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Chro_4372	COG1605	Chorismate mutase
Chro_4372	COG0077	Prephenate dehydratase
Chro_4374	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Chro_4375	COG1530	ribonuclease E activity
Chro_4380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Chro_4383	COG1216	Glycosyl transferase, family 2
Chro_4383	COG0463	Glycosyl transferase, family 2
Chro_4384	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Chro_4386	COG3437	response regulator, receiver
Chro_4386	COG2770	Histidine kinase
Chro_4390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Chro_4392	COG1324	tolerance protein
Chro_4393	COG1194	a g-specific adenine glycosylase
Chro_4395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Chro_4400	COG1160	GTP binding
Chro_4403	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Chro_4404	COG0298	carbon dioxide binding
Chro_4407	COG0205	6-phosphofructokinase activity
Chro_4413	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Chro_4415	COG0438	transferase activity, transferring glycosyl groups
Chro_4419	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_4427	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Chro_4429	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_4433	COG3266	domain, Protein
Chro_4433	COG0515	serine threonine protein kinase
Chro_4440	COG0523	cobalamin synthesis protein
Chro_4444	COG0515	serine threonine protein kinase
Chro_4444	COG1357	PFAM Pentapeptide repeats (8 copies)
Chro_4446	COG0765	amino acid transport
Chro_4447	COG1126	abc transporter atp-binding protein
Chro_4448	COG1301	dicarboxylic acid transport
Chro_4451	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Chro_4455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Chro_4458	COG1316	TRANSCRIPTIONal
Chro_4459	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Chro_4459	COG2205	protein histidine kinase activity
Chro_4460	COG4251	negative regulation of phosphorylation
Chro_4461	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Chro_4461	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Chro_4465	COG0612	Peptidase, M16
Chro_4466	COG0024	Methionine aminopeptidase
Chro_4470	COG0076	glutamate decarboxylase activity
Chro_4471	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Chro_4479	COG0450	alkyl hydroperoxide reductase
Chro_4480	COG0519	Catalyzes the synthesis of GMP from XMP
Chro_4481	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_4484	COG1283	sodium-dependent phosphate transmembrane transporter activity
Chro_4485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Chro_4486	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Chro_4488	COG1316	TRANSCRIPTIONal
Chro_4490	COG0628	permease
Chro_4492	COG1045	serine acetyltransferase
Chro_4494	COG0242	peptide deformylase activity
Chro_4502	COG0066	3-isopropylmalate dehydratase activity
Chro_4505	COG2205	protein histidine kinase activity
Chro_4505	COG2198	Histidine kinase
Chro_4505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Chro_4505	COG0784	Response regulator, receiver
Chro_4512	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_4514	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Chro_4519	COG1120	ATPase activity
Chro_4524	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Chro_4527	COG3956	TIGRFAM MazG family protein
Chro_4529	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Chro_4531	COG0762	integral membrane protein
Chro_4534	COG1070	Carbohydrate kinase
Chro_4547	COG5361	Conserved Protein
Chro_4548	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Chro_4549	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Chro_4551	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Chro_4552	COG1218	3'(2'),5'-bisphosphate nucleotidase
Chro_4553	COG0243	molybdopterin cofactor binding
Chro_4557	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Chro_4561	COG1982	Orn Lys Arg decarboxylase major
Chro_4562	COG5002	protein histidine kinase activity
Chro_4566	COG1404	Belongs to the peptidase S8 family
Chro_4567	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Chro_4569	COG0725	ABC transporter, periplasmic molybdate-binding protein
Chro_4578	COG5420	small protein containing a coiled-coil domain
Chro_4581	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Chro_4589	COG0535	radical SAM domain protein
Chro_4589	COG1433	Dinitrogenase iron-molybdenum cofactor
Chro_4590	COG1045	serine acetyltransferase
Chro_4592	COG0783	Belongs to the Dps family
Chro_4594	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Chro_4595	COG5554	nitrogen fixation
Chro_4599	COG1799	cell septum assembly
Chro_4602	COG3903	Transcriptional regulator
Chro_4602	COG2319	Wd-40 repeat
Chro_4609	COG1216	Glycosyl transferase, family 2
Chro_4612	COG0438	transferase activity, transferring glycosyl groups
Chro_4620	COG0438	transferase activity, transferring glycosyl groups
Chro_4626	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_4629	COG0438	transferase activity, transferring glycosyl groups
Chro_4633	COG1215	transferase activity, transferring glycosyl groups
Chro_4635	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Chro_4636	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Chro_4637	COG0489	protein tyrosine kinase activity
Chro_4639	COG1696	Membrane protein involved in D-alanine export
Chro_4645	COG0463	Glycosyl transferase, family 2
Chro_4650	COG0531	amino acid
Chro_4652	COG2161	toxin-antitoxin pair type II binding
Chro_4655	COG1090	epimerase
Chro_4659	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Chro_4660	COG0069	glutamate synthase activity
Chro_4662	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Chro_4665	COG0446	pyridine nucleotide-disulphide oxidoreductase
Chro_4665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Chro_4669	COG0542	response to heat
Chro_4670	COG0138	bifunctional purine biosynthesis protein purh
Chro_4675	COG0438	transferase activity, transferring glycosyl groups
Chro_4676	COG0438	transferase activity, transferring glycosyl groups
Chro_4677	COG1216	Glycosyl transferase, family 2
Chro_4677	COG1442	glycosyl transferase family 8
Chro_4685	COG3206	protein involved in exopolysaccharide biosynthesis
Chro_4685	COG0489	protein tyrosine kinase activity
Chro_4686	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Chro_4687	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Chro_4692	COG1254	Belongs to the acylphosphatase family
Chro_4693	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Chro_4694	COG0514	ATP-dependent DNA helicase (RecQ)
Chro_4698	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Chro_4699	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Chro_4700	COG1121	(ABC) transporter
Chro_4701	COG0803	Belongs to the bacterial solute-binding protein 9 family
Chro_4704	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_4708	COG0363	glucosamine-6-phosphate deaminase activity
Chro_4709	COG4991	sh3 domain protein
Chro_4709	COG3103	Sh3 type 3 domain protein
Chro_4709	COG0860	N-Acetylmuramoyl-L-alanine amidase
Chro_4710	COG0504	CTP synthase activity
Chro_4712	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Chro_4717	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Chro_4720	COG2159	amidohydrolase
Chro_4721	COG1032	radical SAM domain protein
Chro_4727	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Chro_4728	COG0095	Lipoate-protein ligase
Chro_4730	COG2226	methyltransferase
Chro_4731	COG0174	glutamine synthetase
Chro_4733	COG2390	Transcriptional regulator
Chro_4736	COG1175	transmembrane transport
Chro_4738	COG3842	ATPase activity
Chro_4741	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Chro_4743	COG1116	anion transmembrane transporter activity
Chro_4744	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Chro_4745	COG1335	isochorismatase
Chro_4746	COG0534	Mate efflux family protein
Chro_4747	COG0702	epimerase
Chro_4749	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_4750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Chro_4754	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Chro_4756	COG5002	protein histidine kinase activity
Chro_4757	COG0438	transferase activity, transferring glycosyl groups
Chro_4760	COG3540	Alkaline phosphatase
Chro_4763	COG0643	Histidine kinase
Chro_4763	COG2198	Histidine kinase
Chro_4764	COG0840	transmembrane signaling receptor activity
Chro_4764	COG2203	Gaf domain
Chro_4771	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_4772	COG0431	NADPH-dependent FMN reductase
Chro_4774	COG3706	GGDEF domain
Chro_4774	COG0745	RESPONSE REGULATOR receiver
Chro_4777	COG1598	PFAM Uncharacterised protein family UPF0150
Chro_4779	COG0028	Belongs to the TPP enzyme family
Chro_4784	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Chro_4785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Chro_4786	COG0051	transcription antitermination factor activity, RNA binding
Chro_4787	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Chro_4789	COG0049	tRNA binding
Chro_4790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Chro_4791	COG0316	Belongs to the HesB IscA family
Chro_4794	COG0840	transmembrane signaling receptor activity
Chro_4794	COG2203	Gaf domain
Chro_4795	COG3781	membrane
Chro_4796	COG0489	protein tyrosine kinase activity
Chro_4798	COG0110	maltose O-acetyltransferase activity
Chro_4800	COG0438	transferase activity, transferring glycosyl groups
Chro_4801	COG0438	transferase activity, transferring glycosyl groups
Chro_4802	COG0438	transferase activity, transferring glycosyl groups
Chro_4805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_4806	COG1216	Glycosyl transferase, family 2
Chro_4806	COG1442	glycosyl transferase family 8
Chro_4808	COG0438	transferase activity, transferring glycosyl groups
Chro_4810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_4816	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Chro_4817	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_4822	COG0673	inositol 2-dehydrogenase activity
Chro_4829	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Chro_4832	COG0495	leucyl-tRNA aminoacylation
Chro_4835	COG1595	DNA-templated transcription, initiation
Chro_4838	COG0739	heme binding
Chro_4838	COG1196	nuclear chromosome segregation
Chro_4838	COG0741	lytic transglycosylase activity
Chro_4839	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Chro_4839	COG4651	solute:proton antiporter activity
Chro_4841	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Chro_4844	COG3903	Transcriptional regulator
Chro_4844	COG2319	Wd-40 repeat
Chro_4846	COG2205	protein histidine kinase activity
Chro_4847	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Chro_4849	COG0009	L-threonylcarbamoyladenylate synthase
Chro_4850	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Chro_4861	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Chro_4862	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Chro_4866	COG2226	methyltransferase
Chro_4876	COG0750	zinc metalloprotease
Chro_4877	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Chro_4880	COG0454	-acetyltransferase
Chro_4885	COG0163	prenyltransferase activity
Chro_4886	COG0557	exoribonuclease II activity
Chro_4890	COG1331	Highly conserved protein containing a thioredoxin domain
Chro_4891	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Chro_4892	COG1215	transferase activity, transferring glycosyl groups
Chro_4893	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Chro_4897	COG1733	regulation of RNA biosynthetic process
Chro_4902	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Chro_4903	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Chro_4905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Chro_4907	COG3266	domain, Protein
Chro_4907	COG0515	serine threonine protein kinase
Chro_4909	COG0745	RESPONSE REGULATOR receiver
Chro_4920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Chro_4921	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Chro_4923	COG3850	Histidine kinase
Chro_4923	COG4999	Histidine kinase
Chro_4923	COG3437	response regulator, receiver
Chro_4923	COG2205	protein histidine kinase activity
Chro_4928	COG0772	Belongs to the SEDS family
Chro_4929	COG0489	protein tyrosine kinase activity
Chro_4930	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Chro_4932	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Chro_4933	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Chro_4934	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Chro_4935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Chro_4938	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Chro_4939	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Chro_4940	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Chro_4944	COG0752	glycyl-tRNA synthetase alpha subunit
Chro_4946	COG0402	S-adenosylhomocysteine deaminase activity
Chro_4952	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Chro_4954	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Chro_4960	COG3118	belongs to the thioredoxin family
Chro_4964	COG0071	Belongs to the small heat shock protein (HSP20) family
Chro_4965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Chro_4972	COG0515	serine threonine protein kinase
Chro_4979	COG2082	Precorrin-8x methylmutase
Chro_4982	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Chro_4983	COG0830	nickel cation binding
Chro_4984	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_4985	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Chro_4986	COG1959	2 iron, 2 sulfur cluster binding
Chro_4988	COG0038	chloride channel
Chro_4990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Chro_4996	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Chro_4997	COG2252	PERMEase
Chro_5000	COG0166	Belongs to the GPI family
Chro_5005	COG0564	pseudouridine synthase activity
Chro_5007	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Chro_5013	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Chro_5013	COG2022	thiamine diphosphate biosynthetic process
Chro_5014	COG0596	Alpha beta hydrolase
Chro_5019	COG2234	aminopeptidase activity
Chro_5022	COG0392	lysyltransferase activity
Chro_5037	COG0702	epimerase
Chro_5043	COG0515	serine threonine protein kinase
Chro_5062	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Chro_5063	COG0395	ABC-type sugar transport system, permease component
Chro_5064	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Chro_5071	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Chro_5073	COG0515	serine threonine protein kinase
Chro_5074	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Chro_5075	COG0170	dolichyl monophosphate biosynthetic process
Chro_5076	COG1252	NADH dehydrogenase
Chro_5078	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Chro_5086	COG1234	tRNA 3'-trailer cleavage
Chro_5095	COG0395	ABC-type sugar transport system, permease component
Chro_5108	COG0515	serine threonine protein kinase
Chro_5109	COG0538	isocitrate dehydrogenase activity
Chro_5112	COG3064	Membrane
Chro_5112	COG0515	serine threonine protein kinase
Chro_5112	COG4991	sh3 domain protein
Chro_5125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Chro_5126	COG0193	aminoacyl-tRNA hydrolase activity
Chro_5131	COG0590	tRNA wobble adenosine to inosine editing
Chro_5133	COG5002	protein histidine kinase activity
Chro_5133	COG0784	Response regulator, receiver
Chro_5133	COG2205	protein histidine kinase activity
Chro_5134	COG5001	Diguanylate cyclase
Chro_5139	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Chro_5149	COG3266	domain, Protein
Chro_5149	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Chro_5151	COG0195	Participates in both transcription termination and antitermination
Chro_5152	COG0779	Required for maturation of 30S ribosomal subunits
Chro_5155	COG2207	Transcriptional regulator
Chro_5163	COG0312	modulator of DNA gyrase
Chro_5164	COG0312	modulator of DNA gyrase
Chro_5165	COG5592	hemerythrin HHE cation binding domain
Chro_5167	COG0515	serine threonine protein kinase
Chro_5167	COG2815	serine threonine protein kinase
Chro_5168	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Chro_5171	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Chro_5171	COG0662	Cupin 2, conserved barrel domain protein
Chro_5174	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Chro_5175	COG2207	Transcriptional regulator
Chro_5179	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Chro_5181	COG5002	protein histidine kinase activity
Chro_5182	COG0728	peptidoglycan biosynthetic process
Chro_5185	COG0745	RESPONSE REGULATOR receiver
Chro_5187	COG0745	RESPONSE REGULATOR receiver
Chro_5189	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Chro_5193	COG0405	Gamma-glutamyltransferase
Chro_5197	COG1233	COG1233 Phytoene dehydrogenase and related
Chro_5206	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Chro_5207	COG0735	belongs to the Fur family
Chro_5208	COG0330	HflC and HflK could
Chro_5212	COG0408	coproporphyrinogen oxidase activity
Chro_5218	COG0848	biopolymer transport protein
Chro_5219	COG0811	peptide transport
Chro_5223	COG3546	catalase activity
Chro_5225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Chro_5229	COG1012	belongs to the aldehyde dehydrogenase family
Chro_5230	COG1830	Aldolase
Chro_5233	COG0436	Aminotransferase
Chro_5234	COG0154	amidase activity
Chro_5237	COG2267	carboxylic ester hydrolase activity
Chro_5238	COG0438	transferase activity, transferring glycosyl groups
Chro_5240	COG0438	transferase activity, transferring glycosyl groups
Chro_5244	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Chro_5247	COG2171	N-acyltransferase activity
Chro_5251	COG0003	Pfam Anion-transporting ATPase
Chro_5252	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Chro_5254	COG0010	Belongs to the arginase family
Chro_5256	COG0528	UMP kinase activity
Chro_5257	COG0233	cytoplasmic translational termination
Chro_5267	COG0587	DNA-directed DNA polymerase activity
Chro_5269	COG0587	DNA-directed DNA polymerase activity
Chro_5272	COG0515	serine threonine protein kinase
Chro_5279	COG3659	wide pore channel activity
Chro_5282	COG1929	Belongs to the glycerate kinase type-1 family
Chro_5287	COG1653	transport
Chro_5289	COG0505	Belongs to the CarA family
Chro_5297	COG0583	DNA-binding transcription factor activity
Chro_5298	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Chro_5301	COG1842	Phage shock protein A
Chro_5302	COG1842	Phage shock protein A
Chro_5304	COG3118	belongs to the thioredoxin family
Chro_5305	COG0436	Aminotransferase
Chro_5306	COG0784	Response regulator, receiver
Chro_5313	COG1850	ribulose-bisphosphate carboxylase activity
Chro_5315	COG4451	ribulose bisphosphate carboxylase, small
Chro_5317	COG4451	ribulose bisphosphate carboxylase, small
Chro_5317	COG0464	growth
Chro_5323	COG0438	transferase activity, transferring glycosyl groups
Chro_5330	COG1132	(ABC) transporter
Chro_5333	COG0837	glucose binding
Chro_5342	COG4638	Rieske (2fe-2S)
Chro_5343	COG0156	8-amino-7-oxononanoate synthase activity
Chro_5346	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Chro_5347	COG1136	(ABC) transporter
Chro_5347	COG0577	efflux transmembrane transporter activity
Chro_5350	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Chro_5351	COG0802	atpase or kinase
Chro_5352	COG1280	lysine exporter protein (LysE YggA)
Chro_5354	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Chro_5356	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Chro_5359	COG2217	Heavy metal translocating P-type atpase
Chro_5363	COG0412	Dienelactone hydrolase
Chro_5365	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Chro_5366	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Chro_5367	COG2205	protein histidine kinase activity
Chro_5367	COG0784	Response regulator, receiver
Chro_5369	COG4251	negative regulation of phosphorylation
Chro_5374	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Chro_5376	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Chro_5376	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Chro_5377	COG3932	Exopolysaccharide synthesis, ExoD
Chro_5379	COG0398	Pfam SNARE associated Golgi protein
Chro_5381	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Chro_5381	COG0784	Response regulator, receiver
Chro_5381	COG2205	protein histidine kinase activity
Chro_5381	COG2198	Histidine kinase
Chro_5382	COG0784	Response regulator, receiver
Chro_5383	COG4251	negative regulation of phosphorylation
Chro_5384	COG1834	amidinotransferase
Chro_5386	COG0071	Belongs to the small heat shock protein (HSP20) family
Chro_5388	COG0405	Gamma-glutamyltransferase
Chro_5390	COG5002	protein histidine kinase activity
Chro_5392	COG0784	Response regulator, receiver
Chro_5393	COG4251	negative regulation of phosphorylation
Chro_5394	COG0673	inositol 2-dehydrogenase activity
Chro_5395	COG0745	RESPONSE REGULATOR receiver
Chro_5397	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Chro_5398	COG0271	Belongs to the BolA IbaG family
Chro_5401	COG0590	tRNA wobble adenosine to inosine editing
Chro_5402	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Chro_5405	COG1494	fructose-1,6-bisphosphatase
Chro_5406	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Chro_5408	COG2361	Protein of unknown function DUF86
Chro_5412	COG0724	RNA recognition motif
Chro_5413	COG0514	ATP-dependent DNA helicase (RecQ)
Chro_5417	COG0745	RESPONSE REGULATOR receiver
Chro_5420	COG0840	transmembrane signaling receptor activity
Chro_5420	COG2203	Gaf domain
Chro_5425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Chro_5427	COG0561	phosphatase activity
Chro_5429	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Chro_5436	COG1285	pathogenesis
Chro_5438	COG0515	serine threonine protein kinase
Chro_5442	COG3118	belongs to the thioredoxin family
Chro_5443	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Chro_5444	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Chro_5450	COG0539	negative regulation of cytoplasmic translation
Chro_5451	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Chro_5457	COG0456	acetyltransferase
Chro_5457	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Chro_5463	COG3659	wide pore channel activity
Chro_5466	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Chro_5467	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Chro_5468	COG0019	diaminopimelate decarboxylase activity
Chro_5469	COG0456	acetyltransferase
Chro_5470	COG0542	response to heat
Chro_5473	COG0314	molybdopterin synthase activity
Chro_5475	COG1233	COG1233 Phytoene dehydrogenase and related
Chro_5481	COG0515	serine threonine protein kinase
Chro_5482	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Chro_5483	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Chro_5484	COG0121	glutamine amidotransferase
Chro_5488	COG3663	DNA glycosylase
Chro_5489	COG2816	NAD+ diphosphatase activity
Chro_5490	COG0488	(ABC) transporter
Chro_5492	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Chro_5495	COG0483	inositol monophosphate 1-phosphatase activity
Chro_5498	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Chro_5499	COG1012	belongs to the aldehyde dehydrogenase family
Chro_5500	COG3850	Histidine kinase
Chro_5500	COG3437	response regulator, receiver
Chro_5500	COG2205	protein histidine kinase activity
Chro_5500	COG4999	Histidine kinase
Chro_5501	COG0804	urea catabolic process
Chro_5502	COG0832	Belongs to the urease beta subunit family
Chro_5505	COG3240	lipase activity
Chro_5506	COG1131	(ABC) transporter
Chro_5509	COG0004	ammonium transporteR
Chro_5510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Chro_5512	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Chro_5513	COG2363	Small membrane protein
Chro_5515	COG1012	belongs to the aldehyde dehydrogenase family
Chro_5519	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Chro_5520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Chro_5524	COG1132	(ABC) transporter
Chro_5527	COG2274	protein secretion by the type I secretion system
Chro_5531	COG4251	negative regulation of phosphorylation
Chro_5532	COG0784	Response regulator, receiver
Chro_5533	COG2205	protein histidine kinase activity
Chro_5534	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Chro_5535	COG3657	addiction module killer protein
Chro_5537	COG1126	abc transporter atp-binding protein
Chro_5538	COG0765	amino acid transport
Chro_5539	COG4597	amino acid ABC transporter
Chro_5540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Chro_5545	COG4294	response to UV
Chro_5552	COG1492	cobalamin metabolic process
Chro_5554	COG2814	Major facilitator Superfamily
Chro_5560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Chro_5561	COG0670	Belongs to the BI1 family
Chro_5565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Chro_5566	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Chro_5567	COG0512	Glutamine amidotransferase of anthranilate synthase
Chro_5571	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Chro_5574	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Chro_5574	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Chro_5578	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Chro_5580	COG0432	Pfam Uncharacterised protein family UPF0047
Chro_5581	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Chro_5584	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Chro_5586	COG2094	Belongs to the DNA glycosylase MPG family
Chro_5587	COG1970	mechanosensitive ion channel activity
Chro_5588	COG2226	methyltransferase
Chro_5592	COG0589	response to stress
Chro_5593	COG3659	wide pore channel activity
Chro_5594	COG1959	2 iron, 2 sulfur cluster binding
Chro_5595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Chro_5597	COG0157	Belongs to the NadC ModD family
Chro_5605	COG1461	Dihydroxyacetone kinase
Chro_5606	COG2376	Dihydroxyacetone kinase
Chro_5608	COG0745	RESPONSE REGULATOR receiver
Chro_5609	COG0242	peptide deformylase activity
Chro_5610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_5611	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Chro_5616	COG1993	acr, cog1993
Chro_5619	COG0730	response to heat
Chro_5620	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Chro_5624	COG3706	GGDEF domain
Chro_5625	COG3781	membrane
Chro_5626	COG5002	protein histidine kinase activity
Chro_5629	COG3546	catalase activity
Chro_5630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Chro_5636	COG1937	Protein conserved in bacteria
Chro_5643	COG2132	Multicopper oxidase
Chro_5652	COG2217	Heavy metal translocating P-type atpase
Chro_5653	COG2132	Multicopper oxidase
Chro_5655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Chro_5657	COG0716	FMN binding
Chro_5659	COG3335	DDE superfamily endonuclease
Chro_5664	COG2217	Heavy metal translocating P-type atpase
Chro_5666	COG0789	Transcriptional regulator
Chro_5668	COG2226	methyltransferase
Chro_5669	COG1595	DNA-templated transcription, initiation
Chro_5671	COG2226	methyltransferase
Chro_5681	COG2226	methyltransferase
Chro_5682	COG0628	permease
Chro_5684	COG1950	PFAM Membrane protein of
Chro_5685	COG0668	transmembrane transport
Chro_5690	COG2132	Multicopper oxidase
Chro_5692	COG1742	UPF0060 membrane protein
Chro_5698	COG4243	Vitamin k epoxide reductase
Chro_5699	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Chro_5706	COG0640	Transcriptional regulator
Chro_5708	COG4243	Vitamin k epoxide reductase
Chro_5709	COG3659	wide pore channel activity
Chro_5710	COG3659	wide pore channel activity
Chro_5720	COG0745	RESPONSE REGULATOR receiver
Chro_5721	COG5002	protein histidine kinase activity
Chro_5725	COG3335	DDE superfamily endonuclease
Chro_5726	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Chro_5727	COG3781	membrane
Chro_5729	COG0739	heme binding
Chro_5731	COG2217	Heavy metal translocating P-type atpase
Chro_5749	COG2319	Wd-40 repeat
Chro_5749	COG3903	Transcriptional regulator
Chro_5751	COG3659	wide pore channel activity
Chro_5756	COG1028	Short-chain dehydrogenase reductase Sdr
Chro_5770	COG4974	Belongs to the 'phage' integrase family
Chro_5794	COG1598	PFAM Uncharacterised protein family UPF0150
Chro_5809	COG2205	protein histidine kinase activity
Chro_5809	COG0784	Response regulator, receiver
Chro_5810	COG2197	response regulator
Chro_5811	COG2124	cytochrome p450
Chro_5812	COG1309	transcriptional regulator
Chro_5825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Chro_5833	COG3795	YCII-related domain
Chro_5834	COG4941	Belongs to the sigma-70 factor family
Chro_5835	COG0346	lactoylglutathione lyase activity
Chro_5847	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Chro_5874	COG1943	Transposase
Chro_5878	COG3549	Plasmid maintenance system killer
Chro_5879	COG3093	addiction module antidote protein HigA
Chro_5883	COG4974	Belongs to the 'phage' integrase family
Chro_5889	COG0571	ribonuclease III activity
Chro_5891	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Chro_5892	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Chro_5899	COG1111	helicase
Chro_5899	COG1205	dead DEAH box helicase
Chro_5907	COG0592	DNA-directed DNA polymerase activity
Chro_5908	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Chro_5918	COG0745	RESPONSE REGULATOR receiver
Chro_5919	COG5002	protein histidine kinase activity
Chro_5921	COG0745	RESPONSE REGULATOR receiver
Chro_5922	COG5000	phosphorelay sensor kinase activity
Chro_5922	COG5002	protein histidine kinase activity
Chro_5926	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Chro_5928	COG0392	lysyltransferase activity
Chro_5930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Chro_5930	COG0392	lysyltransferase activity
Chro_5935	COG0531	amino acid
Chro_5938	COG1309	transcriptional regulator
Chro_5955	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Chro_5961	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Chro_5964	COG5002	protein histidine kinase activity
Chro_5966	COG0730	response to heat
Chro_5975	COG2119	membrane