locus-tag	class	description
CEY12_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEY12_00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEY12_00020	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEY12_00070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEY12_00070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEY12_00075	COG1629	transport
CEY12_00075	COG4206	TonB-dependent receptor
CEY12_00080	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CEY12_00090	COG1082	Xylose isomerase domain protein TIM barrel
CEY12_00095	COG0366	Alpha amylase catalytic
CEY12_00120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEY12_00125	COG1733	regulation of RNA biosynthetic process
CEY12_00130	COG1741	Belongs to the pirin family
CEY12_00140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEY12_00150	COG2267	carboxylic ester hydrolase activity
CEY12_00160	COG0151	Belongs to the GarS family
CEY12_00165	COG0519	Catalyzes the synthesis of GMP from XMP
CEY12_00165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEY12_00175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEY12_00175	COG3153	acetyltransferase
CEY12_00185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEY12_00195	COG0513	Belongs to the DEAD box helicase family
CEY12_00215	COG1979	alcohol dehydrogenase
CEY12_00220	COG1733	regulation of RNA biosynthetic process
CEY12_00240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_00245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEY12_00280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEY12_00285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEY12_00300	COG0531	amino acid
CEY12_00310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEY12_00320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEY12_00320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEY12_00340	COG0671	phosphoesterase, PA-phosphatase related
CEY12_00350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEY12_00360	COG1295	ribonuclease BN
CEY12_00365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEY12_00370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEY12_00385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEY12_00395	COG0745	RESPONSE REGULATOR receiver
CEY12_00400	COG5002	protein histidine kinase activity
CEY12_00435	COG0137	argininosuccinate synthase activity
CEY12_00440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEY12_00445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEY12_00455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEY12_00460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEY12_00465	COG0165	Argininosuccinate lyase
CEY12_00470	COG1522	sequence-specific DNA binding
CEY12_00490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEY12_00515	COG3842	ATPase activity
CEY12_00535	COG2169	Transcriptional regulator
CEY12_00535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEY12_00585	COG0492	ferredoxin-NADP+ reductase activity
CEY12_00615	COG2957	Belongs to the agmatine deiminase family
CEY12_00635	COG1846	Transcriptional regulator
CEY12_00640	COG1077	Cell shape determining protein MreB Mrl
CEY12_00655	COG3279	Response regulator of the LytR AlgR family
CEY12_00705	COG0038	chloride channel
CEY12_00710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_00730	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_00740	COG1917	Cupin 2, conserved barrel domain protein
CEY12_00740	COG2207	Transcriptional regulator
CEY12_00745	COG0667	Aldo Keto reductase
CEY12_00750	COG0596	Alpha beta hydrolase
CEY12_00760	COG0778	Nitroreductase
CEY12_00765	COG1733	regulation of RNA biosynthetic process
CEY12_00890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEY12_00895	COG3852	Histidine kinase
CEY12_00910	COG1136	(ABC) transporter
CEY12_00930	COG0300	oxidoreductase activity
CEY12_00940	COG2207	Transcriptional regulator
CEY12_00940	COG1917	Cupin 2, conserved barrel domain protein
CEY12_00975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEY12_00980	COG0431	NADPH-dependent FMN reductase
CEY12_00990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEY12_01000	COG2318	DinB family
CEY12_01030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_01035	COG1595	DNA-templated transcription, initiation
CEY12_01075	COG5002	protein histidine kinase activity
CEY12_01080	COG5002	protein histidine kinase activity
CEY12_01080	COG0784	Response regulator, receiver
CEY12_01090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEY12_01100	COG0784	Response regulator, receiver
CEY12_01100	COG2205	protein histidine kinase activity
CEY12_01115	COG4221	oxidoreductase activity
CEY12_01135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEY12_01160	COG1733	regulation of RNA biosynthetic process
CEY12_01165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEY12_01175	COG4974	Belongs to the 'phage' integrase family
CEY12_01220	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CEY12_01250	COG4206	TonB-dependent receptor
CEY12_01250	COG1629	transport
CEY12_01370	COG1764	response to oxidative stress
CEY12_01375	COG2207	Transcriptional regulator
CEY12_01380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEY12_01385	COG4232	protein-disulfide reductase activity
CEY12_01390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEY12_01410	COG0667	Aldo Keto reductase
CEY12_01415	COG1132	(ABC) transporter
CEY12_01440	COG1902	pentaerythritol trinitrate reductase activity
CEY12_01465	COG1846	Transcriptional regulator
CEY12_01465	COG0456	acetyltransferase
CEY12_01485	COG2197	response regulator
CEY12_01510	COG1309	transcriptional regulator
CEY12_01515	COG2814	Major facilitator Superfamily
CEY12_01525	COG2207	Transcriptional regulator
CEY12_01525	COG3708	Transcriptional regulator
CEY12_01535	COG4221	oxidoreductase activity
CEY12_01565	COG3832	glyoxalase III activity
CEY12_01570	COG4977	sequence-specific DNA binding
CEY12_01595	COG3590	peptidase
CEY12_01600	COG0656	L-ascorbic acid biosynthetic process
CEY12_01605	COG3275	phosphorelay sensor kinase activity
CEY12_01620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEY12_01620	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_01620	COG4221	oxidoreductase activity
CEY12_01620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEY12_01620	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_01620	COG3321	synthase
CEY12_01620	COG4221	oxidoreductase activity
CEY12_01620	COG3321	synthase
CEY12_01625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEY12_01625	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_01625	COG3321	synthase
CEY12_01625	COG4221	oxidoreductase activity
CEY12_01630	COG4221	oxidoreductase activity
CEY12_01630	COG3321	synthase
CEY12_01630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEY12_01630	COG0300	oxidoreductase activity
CEY12_01635	COG3321	synthase
CEY12_01635	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_01635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEY12_01635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEY12_01635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEY12_01640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEY12_01640	COG2070	2-Nitropropane dioxygenase
CEY12_01645	COG3321	synthase
CEY12_01650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEY12_01660	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEY12_01695	COG1335	isochorismatase
CEY12_01725	COG4585	Histidine kinase
CEY12_01740	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CEY12_01745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEY12_01750	COG1125	glycine betaine transport
CEY12_01750	COG0517	IMP dehydrogenase activity
CEY12_01755	COG1174	glycine betaine transport
CEY12_01760	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEY12_01780	COG0392	lysyltransferase activity
CEY12_01780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CEY12_01795	COG0523	cobalamin synthesis protein
CEY12_01800	COG1785	Belongs to the alkaline phosphatase family
CEY12_01820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_01825	COG1764	response to oxidative stress
CEY12_01830	COG0596	Alpha beta hydrolase
CEY12_01840	COG2814	Major facilitator Superfamily
CEY12_01850	COG3279	Response regulator of the LytR AlgR family
CEY12_01870	COG0025	NhaP-type Na H and K H
CEY12_01890	COG0583	DNA-binding transcription factor activity
CEY12_01900	COG2197	response regulator
CEY12_01915	COG0156	8-amino-7-oxononanoate synthase activity
CEY12_01925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEY12_01935	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CEY12_01935	COG1605	Chorismate mutase
CEY12_01940	COG1162	GTPase activity
CEY12_01950	COG2814	Major facilitator Superfamily
CEY12_01955	COG0105	UTP biosynthetic process
CEY12_01970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEY12_01975	COG1363	Peptidase, m42
CEY12_01990	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEY12_01990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEY12_01995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEY12_02005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEY12_02040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEY12_02045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEY12_02050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEY12_02080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEY12_02085	COG0450	alkyl hydroperoxide reductase
CEY12_02090	COG0612	Peptidase, M16
CEY12_02100	COG2234	aminopeptidase activity
CEY12_02105	COG0357	Ribosomal RNA small subunit methyltransferase G
CEY12_02130	COG1960	acyl-CoA dehydrogenase activity
CEY12_02145	COG1629	transport
CEY12_02145	COG4206	TonB-dependent receptor
CEY12_02160	COG1472	Belongs to the glycosyl hydrolase 3 family
CEY12_02175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEY12_02185	COG0519	Catalyzes the synthesis of GMP from XMP
CEY12_02195	COG0813	purine-nucleoside phosphorylase activity
CEY12_02230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEY12_02255	COG2076	Multidrug Resistance protein
CEY12_02285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEY12_02295	COG1506	peptidase
CEY12_02310	COG0534	Mate efflux family protein
CEY12_02315	COG2204	response regulator
CEY12_02320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEY12_02330	COG1801	Protein of unknown function DUF72
CEY12_02335	COG2217	Heavy metal translocating P-type atpase
CEY12_02345	COG1607	acyl-coa hydrolase
CEY12_02350	COG0724	RNA recognition motif
CEY12_02365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEY12_02375	COG1136	(ABC) transporter
CEY12_02385	COG2003	Belongs to the UPF0758 family
CEY12_02410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEY12_02415	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CEY12_02420	COG0436	Aminotransferase
CEY12_02425	COG2234	aminopeptidase activity
CEY12_02445	COG2814	Major facilitator Superfamily
CEY12_02460	COG4977	sequence-specific DNA binding
CEY12_02460	COG1917	Cupin 2, conserved barrel domain protein
CEY12_02465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEY12_02470	COG0129	dihydroxy-acid dehydratase activity
CEY12_02475	COG0028	Belongs to the TPP enzyme family
CEY12_02485	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEY12_02490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEY12_02495	COG4124	Belongs to the glycosyl hydrolase 26 family
CEY12_02510	COG1349	DNA-binding transcription factor activity
CEY12_02525	COG1088	dTDP-glucose 4,6-dehydratase activity
CEY12_02545	COG0300	oxidoreductase activity
CEY12_02560	COG2169	Transcriptional regulator
CEY12_02605	COG0596	Alpha beta hydrolase
CEY12_02615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEY12_02635	COG3422	double-strand break repair
CEY12_02640	COG1960	acyl-CoA dehydrogenase activity
CEY12_02645	COG0183	Belongs to the thiolase family
CEY12_02655	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEY12_02655	COG1024	Enoyl-CoA hydratase
CEY12_02665	COG1120	ATPase activity
CEY12_02670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEY12_02675	COG3118	belongs to the thioredoxin family
CEY12_02685	COG2949	membrane
CEY12_02695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEY12_02725	COG0528	UMP kinase activity
CEY12_02730	COG0233	cytoplasmic translational termination
CEY12_02745	COG1674	ftsk spoiiie
CEY12_02760	COG1335	isochorismatase
CEY12_02770	COG1333	cytochrome c biogenesis protein
CEY12_02770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEY12_02795	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_02860	COG0791	NLP P60 protein
CEY12_02865	COG2171	N-acyltransferase activity
CEY12_02875	COG0463	Glycosyl transferase, family 2
CEY12_02885	COG0438	transferase activity, transferring glycosyl groups
CEY12_02890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEY12_02895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEY12_02900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEY12_02905	COG0131	Imidazoleglycerol-phosphate dehydratase
CEY12_02915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEY12_02920	COG0107	imidazoleglycerol-phosphate synthase activity
CEY12_02925	COG0140	phosphoribosyl-ATP diphosphatase activity
CEY12_02925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEY12_02930	COG2234	aminopeptidase activity
CEY12_02935	COG2234	aminopeptidase activity
CEY12_02940	COG2234	aminopeptidase activity
CEY12_02945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEY12_02950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEY12_02965	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEY12_02970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEY12_02990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEY12_02995	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEY12_03000	COG0066	3-isopropylmalate dehydratase activity
CEY12_03005	COG0473	3-isopropylmalate dehydrogenase activity
CEY12_03050	COG1960	acyl-CoA dehydrogenase activity
CEY12_03055	COG2356	endonuclease I
CEY12_03075	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEY12_03100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEY12_03105	COG1187	pseudouridine synthase activity
CEY12_03115	COG1335	isochorismatase
CEY12_03120	COG0513	Belongs to the DEAD box helicase family
CEY12_03125	COG2318	DinB family
CEY12_03145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_03150	COG0697	spore germination
CEY12_03160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEY12_03185	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_03195	COG0745	RESPONSE REGULATOR receiver
CEY12_03200	COG5002	protein histidine kinase activity
CEY12_03225	COG0671	phosphoesterase, PA-phosphatase related
CEY12_03230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_03250	COG3871	stress protein (general stress protein 26)
CEY12_03255	COG0025	NhaP-type Na H and K H
CEY12_03275	COG4977	sequence-specific DNA binding
CEY12_03275	COG1917	Cupin 2, conserved barrel domain protein
CEY12_03300	COG2084	Dehydrogenase
CEY12_03310	COG2814	Major facilitator Superfamily
CEY12_03325	COG2814	Major facilitator Superfamily
CEY12_03345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEY12_03380	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEY12_03380	COG1793	dna ligase
CEY12_03385	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_03415	COG2814	Major facilitator Superfamily
CEY12_03420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CEY12_03435	COG2175	clavaminate synthase activity
CEY12_03440	COG0076	glutamate decarboxylase activity
CEY12_03445	COG4264	IucA IucC family
CEY12_03450	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CEY12_03470	COG0318	PFAM AMP-dependent synthetase and ligase
CEY12_03495	COG0156	8-amino-7-oxononanoate synthase activity
CEY12_03500	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEY12_03505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEY12_03520	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_03525	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_03530	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_03535	COG4977	sequence-specific DNA binding
CEY12_03535	COG1917	Cupin 2, conserved barrel domain protein
CEY12_03540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_03545	COG2323	membrane
CEY12_03555	COG0745	RESPONSE REGULATOR receiver
CEY12_03560	COG5002	protein histidine kinase activity
CEY12_03565	COG1285	pathogenesis
CEY12_03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_03625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEY12_03630	COG0477	Major facilitator Superfamily
CEY12_03635	COG1733	regulation of RNA biosynthetic process
CEY12_03640	COG2814	Major facilitator Superfamily
CEY12_03645	COG0183	Belongs to the thiolase family
CEY12_03675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_03685	COG2814	Major facilitator Superfamily
CEY12_03700	COG3279	Response regulator of the LytR AlgR family
CEY12_03730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEY12_03735	COG1733	regulation of RNA biosynthetic process
CEY12_03740	COG0667	Aldo Keto reductase
CEY12_03745	COG0667	Aldo Keto reductase
CEY12_03755	COG3685	Protein conserved in bacteria
CEY12_03765	COG1252	NADH dehydrogenase
CEY12_03775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_03780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEY12_03800	COG0300	oxidoreductase activity
CEY12_03810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEY12_03830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEY12_03835	COG0587	DNA-directed DNA polymerase activity
CEY12_03845	COG1629	transport
CEY12_03845	COG4206	TonB-dependent receptor
CEY12_03855	COG0671	phosphoesterase, PA-phosphatase related
CEY12_03865	COG1285	pathogenesis
CEY12_03870	COG2223	nitrite transmembrane transporter activity
CEY12_03875	COG1349	DNA-binding transcription factor activity
CEY12_03895	COG2814	Major facilitator Superfamily
CEY12_03930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_03935	COG1131	(ABC) transporter
CEY12_03940	COG1131	(ABC) transporter
CEY12_03945	COG0842	Transport permease protein
CEY12_03950	COG1129	ABC transporter
CEY12_03950	COG0842	Transport permease protein
CEY12_03970	COG0798	PFAM Bile acid sodium symporter
CEY12_03980	COG2972	Histidine kinase
CEY12_03985	COG3279	Response regulator of the LytR AlgR family
CEY12_03990	COG1629	transport
CEY12_03990	COG4206	TonB-dependent receptor
CEY12_04020	COG2132	Multicopper oxidase
CEY12_04055	COG2076	Multidrug Resistance protein
CEY12_04065	COG0300	oxidoreductase activity
CEY12_04070	COG3663	DNA glycosylase
CEY12_04075	COG2094	Belongs to the DNA glycosylase MPG family
CEY12_04085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_04090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEY12_04110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEY12_04115	COG0823	Involved in the tonB-independent uptake of proteins
CEY12_04115	COG4946	Tricorn protease homolog
CEY12_04115	COG1506	peptidase
CEY12_04120	COG0006	proline dipeptidase activity
CEY12_04125	COG2207	Transcriptional regulator
CEY12_04130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEY12_04140	COG3938	Belongs to the proline racemase family
CEY12_04145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEY12_04165	COG1959	2 iron, 2 sulfur cluster binding
CEY12_04170	COG0175	sulfate reduction
CEY12_04175	COG0175	sulfate reduction
CEY12_04185	COG1045	serine acetyltransferase
CEY12_04195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEY12_04195	COG1648	precorrin-2 dehydrogenase activity
CEY12_04200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEY12_04250	COG2814	Major facilitator Superfamily
CEY12_04255	COG1733	regulation of RNA biosynthetic process
CEY12_04325	COG2378	regulation of single-species biofilm formation
CEY12_04345	COG0640	Transcriptional regulator
CEY12_04410	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEY12_04440	COG0640	Transcriptional regulator
CEY12_04450	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CEY12_04490	COG1321	iron dependent repressor
CEY12_04495	COG4771	TonB-dependent receptor
CEY12_04505	COG1522	sequence-specific DNA binding
CEY12_04535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEY12_04570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEY12_04600	COG0156	8-amino-7-oxononanoate synthase activity
CEY12_04625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEY12_04630	COG0196	riboflavin kinase activity
CEY12_04655	COG0386	Belongs to the glutathione peroxidase family
CEY12_04665	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEY12_04685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEY12_04700	COG0463	Glycosyl transferase, family 2
CEY12_04715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CEY12_04730	COG1575	Belongs to the MenA family. Type 1 subfamily
CEY12_04765	COG2323	membrane
CEY12_04820	COG0531	amino acid
CEY12_04865	COG2270	Major facilitator Superfamily
CEY12_04870	COG4221	oxidoreductase activity
CEY12_04880	COG0183	Belongs to the thiolase family
CEY12_04895	COG2211	Major facilitator Superfamily
CEY12_04905	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CEY12_04960	COG0572	uridine kinase
CEY12_04970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEY12_04975	COG1253	flavin adenine dinucleotide binding
CEY12_04980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEY12_04985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEY12_04990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEY12_04995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEY12_05000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEY12_05005	COG0356	it plays a direct role in the translocation of protons across the membrane
CEY12_05015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEY12_05035	COG1702	phosphate starvation-inducible protein PhoH
CEY12_05045	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEY12_05060	COG0360	Binds together with S18 to 16S ribosomal RNA
CEY12_05065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEY12_05070	COG0359	binds to the 23S rRNA
CEY12_05095	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_05115	COG2176	DNA-directed DNA polymerase activity
CEY12_05120	COG2967	ApaG domain
CEY12_05125	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEY12_05145	COG0297	glycogen (starch) synthase activity
CEY12_05150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEY12_05160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEY12_05180	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CEY12_05205	COG4242	Belongs to the peptidase S51 family
CEY12_05210	COG1446	asparaginase
CEY12_05220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEY12_05235	COG0124	histidyl-tRNA synthetase
CEY12_05240	COG1285	pathogenesis
CEY12_05250	COG0629	single-stranded DNA binding
CEY12_05270	COG1090	epimerase
CEY12_05275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEY12_05320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEY12_05325	COG0484	heat shock protein binding
CEY12_05335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_05340	COG1538	Outer membrane efflux protein
CEY12_05355	COG2996	Protein conserved in bacteria
CEY12_05370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEY12_05390	COG0438	transferase activity, transferring glycosyl groups
CEY12_05400	COG0514	ATP-dependent DNA helicase (RecQ)
CEY12_05405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEY12_05405	COG0517	IMP dehydrogenase activity
CEY12_05415	COG0805	protein transport
CEY12_05430	COG3852	Histidine kinase
CEY12_05445	COG3340	Belongs to the peptidase S51 family
CEY12_05460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEY12_05490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEY12_05515	COG0009	L-threonylcarbamoyladenylate synthase
CEY12_05520	COG3022	response to hydroperoxide
CEY12_05525	COG2890	protein-(glutamine-N5) methyltransferase activity
CEY12_05535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_05550	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_05580	COG2972	Histidine kinase
CEY12_05585	COG3279	Response regulator of the LytR AlgR family
CEY12_05610	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_05630	COG0012	GTP binding
CEY12_05635	COG1528	Iron-storage protein
CEY12_05640	COG1649	PFAM Uncharacterised BCR, COG1649
CEY12_05670	COG2183	response to ionizing radiation
CEY12_05695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEY12_05705	COG2814	Major facilitator Superfamily
CEY12_05715	COG3279	Response regulator of the LytR AlgR family
CEY12_05740	COG0477	Major facilitator Superfamily
CEY12_05750	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_05775	COG1917	Cupin 2, conserved barrel domain protein
CEY12_05775	COG2207	Transcriptional regulator
CEY12_05780	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_05800	COG2706	6-phosphogluconolactonase activity
CEY12_05870	COG0363	glucosamine-6-phosphate deaminase activity
CEY12_05875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEY12_05880	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CEY12_05895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_05920	COG2885	chlorophyll binding
CEY12_05945	COG4977	sequence-specific DNA binding
CEY12_05945	COG1917	Cupin 2, conserved barrel domain protein
CEY12_06145	COG0085	RNA polymerase activity
CEY12_06400	COG0531	amino acid
CEY12_06475	COG1131	(ABC) transporter
CEY12_06480	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEY12_06495	COG3275	phosphorelay sensor kinase activity
CEY12_06515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEY12_06535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEY12_06545	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEY12_06545	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEY12_06555	COG0484	heat shock protein binding
CEY12_06570	COG1191	sigma factor activity
CEY12_06610	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_06685	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEY12_06695	COG1733	regulation of RNA biosynthetic process
CEY12_06700	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_06715	COG3275	phosphorelay sensor kinase activity
CEY12_06720	COG3279	Response regulator of the LytR AlgR family
CEY12_06740	COG2814	Major facilitator Superfamily
CEY12_06745	COG0667	Aldo Keto reductase
CEY12_06750	COG2207	Transcriptional regulator
CEY12_06750	COG0662	Cupin 2, conserved barrel domain protein
CEY12_06780	COG3059	membrane
CEY12_06790	COG1595	DNA-templated transcription, initiation
CEY12_06795	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_06800	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_06805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEY12_06815	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CEY12_06825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEY12_06835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEY12_06840	COG0673	inositol 2-dehydrogenase activity
CEY12_06860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEY12_06880	COG0592	DNA-directed DNA polymerase activity
CEY12_06885	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEY12_06905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEY12_06945	COG4206	TonB-dependent receptor
CEY12_06945	COG1629	transport
CEY12_06960	COG1393	Belongs to the ArsC family
CEY12_06965	COG1428	Deoxynucleoside kinase
CEY12_06990	COG0025	NhaP-type Na H and K H
CEY12_07060	COG4574	serine-type endopeptidase inhibitor activity
CEY12_07075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEY12_07100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEY12_07155	COG2140	Oxalate decarboxylase
CEY12_07160	COG2186	Transcriptional regulator
CEY12_07190	COG1131	(ABC) transporter
CEY12_07195	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CEY12_07210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEY12_07265	COG0022	dehydrogenase e1 component
CEY12_07295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEY12_07300	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEY12_07315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_07320	COG0673	inositol 2-dehydrogenase activity
CEY12_07340	COG1506	peptidase
CEY12_07340	COG0823	Involved in the tonB-independent uptake of proteins
CEY12_07350	COG1950	PFAM Membrane protein of
CEY12_07360	COG0584	glycerophosphoryl diester phosphodiesterase
CEY12_07365	COG0584	glycerophosphoryl diester phosphodiesterase
CEY12_07390	COG1609	Transcriptional regulator
CEY12_07395	COG0246	Mannitol dehydrogenase
CEY12_07400	COG0738	Major facilitator superfamily
CEY12_07420	COG2972	Histidine kinase
CEY12_07490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEY12_07495	COG2011	ABC-type metal ion transport system permease component
CEY12_07500	COG1464	Belongs to the NlpA lipoprotein family
CEY12_07505	COG1472	Belongs to the glycosyl hydrolase 3 family
CEY12_07525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_07545	COG2807	transmembrane transport
CEY12_07555	COG1611	Belongs to the LOG family
CEY12_07565	COG1522	sequence-specific DNA binding
CEY12_07570	COG4106	trans-aconitate 2-methyltransferase activity
CEY12_07595	COG1506	peptidase
CEY12_07595	COG0823	Involved in the tonB-independent uptake of proteins
CEY12_07600	COG1846	Transcriptional regulator
CEY12_07605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEY12_07610	COG2207	Transcriptional regulator
CEY12_07620	COG4771	TonB-dependent receptor
CEY12_07685	COG2197	response regulator
CEY12_07820	COG2066	Belongs to the glutaminase family
CEY12_07865	COG1073	alpha beta
CEY12_07870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEY12_07875	COG0318	PFAM AMP-dependent synthetase and ligase
CEY12_07875	COG3321	synthase
CEY12_07875	COG0300	oxidoreductase activity
CEY12_07875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEY12_07875	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_07880	COG3321	synthase
CEY12_07880	COG0604	alcohol dehydrogenase
CEY12_07935	COG0778	Nitroreductase
CEY12_07940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_07955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEY12_07980	COG0006	proline dipeptidase activity
CEY12_08020	COG0829	nickel cation binding
CEY12_08025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CEY12_08030	COG0830	nickel cation binding
CEY12_08035	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CEY12_08045	COG0804	urea catabolic process
CEY12_08050	COG0832	Belongs to the urease beta subunit family
CEY12_08055	COG0831	urea catabolic process
CEY12_08065	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_08080	COG3118	belongs to the thioredoxin family
CEY12_08090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEY12_08095	COG0598	Magnesium transport protein CorA
CEY12_08115	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEY12_08120	COG1733	regulation of RNA biosynthetic process
CEY12_08125	COG0519	Catalyzes the synthesis of GMP from XMP
CEY12_08140	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_08160	COG2814	Major facilitator Superfamily
CEY12_08175	COG1309	transcriptional regulator
CEY12_08185	COG0470	DNA polymerase III
CEY12_08190	COG1764	response to oxidative stress
CEY12_08220	COG1051	belongs to the nudix hydrolase family
CEY12_08225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEY12_08255	COG0748	coenzyme F420 binding
CEY12_08260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CEY12_08270	COG4682	membrane
CEY12_08285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEY12_08290	COG0697	spore germination
CEY12_08300	COG0475	glutathione-regulated potassium exporter activity
CEY12_08300	COG0589	response to stress
CEY12_08310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEY12_08320	COG0730	response to heat
CEY12_08330	COG0346	lactoylglutathione lyase activity
CEY12_08350	COG1022	Amp-dependent synthetase and ligase
CEY12_08380	COG2267	carboxylic ester hydrolase activity
CEY12_08385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CEY12_08390	COG0668	transmembrane transport
CEY12_08420	COG1193	negative regulation of DNA recombination
CEY12_08435	COG1607	acyl-coa hydrolase
CEY12_08470	COG1169	isochorismate synthase
CEY12_08485	COG2095	MarC family integral membrane protein
CEY12_08500	COG2304	oxidoreductase activity
CEY12_08505	COG2304	oxidoreductase activity
CEY12_08525	COG0714	Associated with various cellular activities
CEY12_08555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEY12_08590	COG0492	ferredoxin-NADP+ reductase activity
CEY12_08605	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEY12_08610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEY12_08620	COG4948	Mandelate Racemase Muconate Lactonizing
CEY12_08625	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEY12_08630	COG0527	aspartate kinase activity
CEY12_08675	COG0596	Alpha beta hydrolase
CEY12_08680	COG2207	Transcriptional regulator
CEY12_08680	COG4753	response regulator
CEY12_08700	COG3876	Protein conserved in bacteria
CEY12_08730	COG1301	dicarboxylic acid transport
CEY12_08740	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_08750	COG0657	acetylesterase activity
CEY12_08750	COG2755	lipolytic protein G-D-S-L family
CEY12_08755	COG1629	transport
CEY12_08755	COG4206	TonB-dependent receptor
CEY12_08765	COG3425	synthase
CEY12_08770	COG0308	aminopeptidase N
CEY12_08810	COG5002	protein histidine kinase activity
CEY12_08815	COG0745	RESPONSE REGULATOR receiver
CEY12_08835	COG0402	S-adenosylhomocysteine deaminase activity
CEY12_08845	COG0402	S-adenosylhomocysteine deaminase activity
CEY12_08850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEY12_08860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CEY12_08915	COG0617	tRNA 3'-terminal CCA addition
CEY12_08920	COG0009	L-threonylcarbamoyladenylate synthase
CEY12_08935	COG0456	acetyltransferase
CEY12_08945	COG0626	cystathionine gamma-synthase activity
CEY12_08955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEY12_08970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEY12_08980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEY12_08995	COG2732	(Barnase) inhibitor
CEY12_09000	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CEY12_09020	COG1733	regulation of RNA biosynthetic process
CEY12_09030	COG1309	transcriptional regulator
CEY12_09035	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CEY12_09040	COG0667	Aldo Keto reductase
CEY12_09085	COG2267	carboxylic ester hydrolase activity
CEY12_09105	COG4251	negative regulation of phosphorylation
CEY12_09115	COG0471	metal ion transport
CEY12_09125	COG1053	succinate dehydrogenase
CEY12_09130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEY12_09205	COG1401	restriction endodeoxyribonuclease activity
CEY12_09225	COG0582	viral genome integration into host DNA
CEY12_09295	COG4974	Belongs to the 'phage' integrase family
CEY12_09305	COG0443	Heat shock 70 kDa protein
CEY12_09320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEY12_09325	COG0248	Ppx GppA phosphatase
CEY12_09340	COG0745	RESPONSE REGULATOR receiver
CEY12_09350	COG2268	Band 7 protein
CEY12_09360	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEY12_09365	COG0489	protein tyrosine kinase activity
CEY12_09390	COG1301	dicarboxylic acid transport
CEY12_09415	COG2226	methyltransferase
CEY12_09420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEY12_09425	COG0010	Belongs to the arginase family
CEY12_09430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEY12_09440	COG2365	Tyrosine phosphatase family
CEY12_09470	COG2378	regulation of single-species biofilm formation
CEY12_09480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEY12_09485	COG1132	(ABC) transporter
CEY12_09495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEY12_09495	COG1017	nitric oxide dioxygenase activity
CEY12_09500	COG1959	2 iron, 2 sulfur cluster binding
CEY12_09505	COG1137	ATPase activity
CEY12_09520	COG0113	porphobilinogen synthase activity
CEY12_09530	COG4152	abc transporter atp-binding protein
CEY12_09535	COG1668	transmembrane transport
CEY12_09545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEY12_09550	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEY12_09555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEY12_09560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEY12_09565	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEY12_09565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEY12_09570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEY12_09575	COG1078	dGTPase activity
CEY12_09595	COG0708	Exodeoxyribonuclease III
CEY12_09615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEY12_09620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEY12_09630	COG0438	transferase activity, transferring glycosyl groups
CEY12_09640	COG0463	Glycosyl transferase, family 2
CEY12_09645	COG0297	glycogen (starch) synthase activity
CEY12_09680	COG3206	protein involved in exopolysaccharide biosynthesis
CEY12_09680	COG0489	protein tyrosine kinase activity
CEY12_09695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEY12_09700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEY12_09710	COG0297	glycogen (starch) synthase activity
CEY12_09730	COG1086	Polysaccharide biosynthesis protein
CEY12_09775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEY12_09780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CEY12_09785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEY12_09790	COG3206	protein involved in exopolysaccharide biosynthesis
CEY12_09790	COG0489	protein tyrosine kinase activity
CEY12_09810	COG2137	regulation of response to DNA damage stimulus
CEY12_09815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEY12_09820	COG3634	alkyl hydroperoxide reductase activity
CEY12_09835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_09845	COG1136	(ABC) transporter
CEY12_09845	COG0577	efflux transmembrane transporter activity
CEY12_09850	COG1136	(ABC) transporter
CEY12_09895	COG1418	mRNA catabolic process
CEY12_09905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEY12_09915	COG0525	valine-tRNA ligase activity
CEY12_09925	COG2326	polyphosphate kinase activity
CEY12_09945	COG0318	PFAM AMP-dependent synthetase and ligase
CEY12_09955	COG0017	Asparaginyl-tRNA synthetase
CEY12_09990	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEY12_09995	COG0228	four-way junction DNA binding
CEY12_10015	COG0339	signal peptide processing
CEY12_10020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEY12_10035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_10065	COG0477	Major facilitator Superfamily
CEY12_10095	COG1309	transcriptional regulator
CEY12_10105	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEY12_10125	COG2310	stress, protein
CEY12_10135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CEY12_10145	COG0259	pyridoxamine-phosphate oxidase activity
CEY12_10150	COG1678	Uncharacterized ACR, COG1678
CEY12_10165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEY12_10180	COG3158	transport of potassium into the cell
CEY12_10185	COG0022	dehydrogenase e1 component
CEY12_10185	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEY12_10195	COG1368	sulfuric ester hydrolase activity
CEY12_10200	COG1183	phosphatidylcholine synthase activity
CEY12_10220	COG0589	response to stress
CEY12_10245	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEY12_10265	COG0488	(ABC) transporter
CEY12_10280	COG4585	Histidine kinase
CEY12_10300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEY12_10315	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEY12_10320	COG0720	synthase
CEY12_10375	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEY12_10380	COG2224	Isocitrate lyase
CEY12_10385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEY12_10395	COG1040	competence protein
CEY12_10405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEY12_10420	COG1160	GTP binding
CEY12_10425	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CEY12_10450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEY12_10460	COG1704	LemA family
CEY12_10485	COG0436	Aminotransferase
CEY12_10495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEY12_10510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEY12_10520	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEY12_10525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEY12_10535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEY12_10545	COG0552	protein localization to endoplasmic reticulum
CEY12_10550	COG2261	transglycosylase associated protein
CEY12_10555	COG0616	signal peptide processing
CEY12_10560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEY12_10560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEY12_10580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEY12_10585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEY12_10585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEY12_10590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEY12_10600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEY12_10610	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEY12_10625	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEY12_10645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEY12_10665	COG2207	Transcriptional regulator
CEY12_10680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_10695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEY12_10700	COG1561	YicC-like family, N-terminal region
CEY12_10705	COG0194	GDP metabolic process
CEY12_10710	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEY12_10730	COG0527	aspartate kinase activity
CEY12_10730	COG0460	homoserine dehydrogenase
CEY12_10735	COG0083	homoserine kinase activity
CEY12_10740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEY12_10745	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEY12_10775	COG3291	Pkd domain containing protein
CEY12_10800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEY12_10815	COG3339	Conserved Protein
CEY12_10820	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEY12_10820	COG0284	orotidine-5'-phosphate decarboxylase activity
CEY12_10850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEY12_10855	COG1522	sequence-specific DNA binding
CEY12_10865	COG0336	Belongs to the RNA methyltransferase TrmD family
CEY12_10870	COG1252	NADH dehydrogenase
CEY12_10885	COG2207	Transcriptional regulator
CEY12_10885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEY12_10895	COG0488	(ABC) transporter
CEY12_10900	COG0673	inositol 2-dehydrogenase activity
CEY12_10915	COG0450	alkyl hydroperoxide reductase
CEY12_10920	COG0668	transmembrane transport
CEY12_10925	COG0045	succinate-CoA ligase (ADP-forming) activity
CEY12_10930	COG2363	Small membrane protein
CEY12_10955	COG0205	6-phosphofructokinase activity
CEY12_10960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEY12_10965	COG2197	response regulator
CEY12_10975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEY12_10985	COG0326	Molecular chaperone. Has ATPase activity
CEY12_11065	COG1113	amino acid transport
CEY12_11100	COG0018	arginyl-trna synthetase
CEY12_11115	COG1629	transport
CEY12_11115	COG4206	TonB-dependent receptor
CEY12_11130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEY12_11135	COG0706	membrane insertase activity
CEY12_11140	COG0504	CTP synthase activity
CEY12_11155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEY12_11205	COG2851	Citrate transporter
CEY12_11210	COG1301	dicarboxylic acid transport
CEY12_11220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEY12_11320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEY12_11340	COG4941	Belongs to the sigma-70 factor family
CEY12_11345	COG1309	transcriptional regulator
CEY12_11355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_11360	COG2318	DinB family
CEY12_11375	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEY12_11375	COG0596	Alpha beta hydrolase
CEY12_11385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEY12_11405	COG0745	RESPONSE REGULATOR receiver
CEY12_11410	COG5002	protein histidine kinase activity
CEY12_11420	COG0477	Major facilitator Superfamily
CEY12_11435	COG1595	DNA-templated transcription, initiation
CEY12_11465	COG1132	(ABC) transporter
CEY12_11475	COG0101	tRNA pseudouridine synthase activity
CEY12_11480	COG1663	tetraacyldisaccharide 4'-kinase activity
CEY12_11485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CEY12_11490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEY12_11500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEY12_11505	COG0366	Alpha amylase catalytic
CEY12_11520	COG2272	Belongs to the type-B carboxylesterase lipase family
CEY12_11535	COG1064	alcohol dehydrogenase
CEY12_11540	COG1733	regulation of RNA biosynthetic process
CEY12_11630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEY12_11640	COG0085	RNA polymerase activity
CEY12_11645	COG0222	ribosome binding
CEY12_11650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEY12_11655	COG0081	regulation of translation
CEY12_11660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEY12_11700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEY12_11730	COG5002	protein histidine kinase activity
CEY12_11735	COG0745	RESPONSE REGULATOR receiver
CEY12_11785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEY12_11805	COG3279	Response regulator of the LytR AlgR family
CEY12_11810	COG3275	phosphorelay sensor kinase activity
CEY12_11830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEY12_11835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEY12_11840	COG0571	ribonuclease III activity
CEY12_11850	COG0469	pyruvate kinase activity
CEY12_11855	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_11860	COG0010	Belongs to the arginase family
CEY12_11865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEY12_11870	COG1228	amidohydrolase
CEY12_11875	COG2255	four-way junction helicase activity
CEY12_11880	COG2808	Putative FMN-binding domain
CEY12_11885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEY12_11890	COG0237	dephospho-CoA kinase activity
CEY12_11915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEY12_11925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEY12_11935	COG1053	succinate dehydrogenase
CEY12_11955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEY12_11975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEY12_11980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEY12_11995	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CEY12_12005	COG1793	dna ligase
CEY12_12005	COG3285	dna ligase
CEY12_12010	COG0668	transmembrane transport
CEY12_12020	COG1862	Preprotein translocase
CEY12_12030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEY12_12035	COG1132	(ABC) transporter
CEY12_12055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CEY12_12095	COG0495	leucyl-tRNA aminoacylation
CEY12_12115	COG1519	Transferase
CEY12_12180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEY12_12185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEY12_12190	COG2884	Cell division ATP-binding protein ftsE
CEY12_12195	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEY12_12200	COG5000	phosphorelay sensor kinase activity
CEY12_12210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEY12_12220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEY12_12225	COG0511	ligase activity, forming carbon-carbon bonds
CEY12_12230	COG0439	Biotin carboxylase
CEY12_12235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEY12_12240	COG0463	Glycosyl transferase, family 2
CEY12_12245	COG0726	polysaccharide deacetylase
CEY12_12295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEY12_12300	COG0825	malonyl-CoA metabolic process
CEY12_12310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEY12_12345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEY12_12360	COG0052	Belongs to the universal ribosomal protein uS2 family
CEY12_12365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEY12_12370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEY12_12385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEY12_12385	COG1703	isobutyryl-CoA mutase activity
CEY12_12385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEY12_12395	COG0076	glutamate decarboxylase activity
CEY12_12420	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEY12_12455	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEY12_12455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEY12_12460	COG0516	GMP reductase activity
CEY12_12460	COG0517	IMP dehydrogenase activity
CEY12_12495	COG0254	rRNA binding
CEY12_12510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEY12_12515	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_12525	COG0823	Involved in the tonB-independent uptake of proteins
CEY12_12545	COG0300	oxidoreductase activity
CEY12_12600	COG4206	TonB-dependent receptor
CEY12_12600	COG1629	transport
CEY12_12710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEY12_12715	COG1442	glycosyl transferase family 8
CEY12_12715	COG1216	Glycosyl transferase, family 2
CEY12_12745	COG2409	Drug exporters of the RND superfamily
CEY12_12755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEY12_12760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEY12_12780	COG1131	(ABC) transporter
CEY12_12805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEY12_12820	COG0726	polysaccharide deacetylase
CEY12_12835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEY12_12845	COG0463	Glycosyl transferase, family 2
CEY12_12870	COG0644	oxidoreductase
CEY12_12880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEY12_12885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEY12_12890	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_12900	COG2986	histidine ammonia-lyase
CEY12_12910	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CEY12_12915	COG0739	heme binding
CEY12_12920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEY12_12925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEY12_12940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEY12_12945	COG2949	membrane
CEY12_12950	COG0180	Tryptophanyl-tRNA synthetase
CEY12_12955	COG5002	protein histidine kinase activity
CEY12_12960	COG0745	RESPONSE REGULATOR receiver
CEY12_12985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEY12_13000	COG1024	Enoyl-CoA hydratase
CEY12_13010	COG4974	Belongs to the 'phage' integrase family
CEY12_13030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_13035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEY12_13045	COG1607	acyl-coa hydrolase
CEY12_13070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEY12_13095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEY12_13100	COG2022	thiamine diphosphate biosynthetic process
CEY12_13105	COG0352	thiamine-phosphate diphosphorylase activity
CEY12_13125	COG0564	pseudouridine synthase activity
CEY12_13135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CEY12_13145	COG2217	Heavy metal translocating P-type atpase
CEY12_13170	COG0348	domain, Protein
CEY12_13215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEY12_13240	COG2181	nitrate reductase activity
CEY12_13240	COG0247	lactate metabolic process
CEY12_13245	COG0247	lactate metabolic process
CEY12_13245	COG2181	nitrate reductase activity
CEY12_13255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEY12_13260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEY12_13265	COG0628	permease
CEY12_13280	COG1960	acyl-CoA dehydrogenase activity
CEY12_13290	COG3420	alginic acid biosynthetic process
CEY12_13295	COG0166	Belongs to the GPI family
CEY12_13300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEY12_13305	COG0602	queuosine metabolic process
CEY12_13310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEY12_13315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEY12_13320	COG1127	ABC transporter
CEY12_13345	COG1703	isobutyryl-CoA mutase activity
CEY12_13395	COG4948	Mandelate Racemase Muconate Lactonizing
CEY12_13415	COG1690	Belongs to the RtcB family
CEY12_13425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEY12_13425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEY12_13435	COG1505	serine-type exopeptidase activity
CEY12_13445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEY12_13450	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEY12_13465	COG2207	Transcriptional regulator
CEY12_13475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CEY12_13475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CEY12_13500	COG2837	iron assimilation
CEY12_13505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEY12_13515	COG0497	DNA recombination
CEY12_13550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEY12_13555	COG0594	ribonuclease P activity
CEY12_13580	COG3829	transcription factor binding
CEY12_13590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEY12_13600	COG0028	Belongs to the TPP enzyme family
CEY12_13605	COG0019	diaminopimelate decarboxylase activity
CEY12_13610	COG2176	DNA-directed DNA polymerase activity
CEY12_13620	COG0433	COG0433 Predicted ATPase
CEY12_13625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEY12_13625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEY12_13635	COG3118	belongs to the thioredoxin family
CEY12_13650	COG0750	zinc metalloprotease
CEY12_13695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEY12_13700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEY12_13725	COG3033	Beta-eliminating lyase
CEY12_13735	COG2133	pyrroloquinoline quinone binding
CEY12_13750	COG0556	nucleotide-excision repair
CEY12_13775	COG3530	Putative quorum-sensing-regulated virulence factor
CEY12_13805	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEY12_13850	COG0653	protein targeting
CEY12_13855	COG4771	TonB-dependent receptor
CEY12_13880	COG1940	carbohydrate kinase activity
CEY12_13885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEY12_13895	COG1629	transport
CEY12_13895	COG4206	TonB-dependent receptor
CEY12_13965	COG2153	protein acetylation
CEY12_13970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEY12_13980	COG2001	Belongs to the MraZ family
CEY12_13985	COG0275	rRNA processing
CEY12_14000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEY12_14010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEY12_14015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEY12_14025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEY12_14035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEY12_14050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEY12_14055	COG1610	YqeY-like protein
CEY12_14095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEY12_14115	COG0745	RESPONSE REGULATOR receiver
CEY12_14135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEY12_14140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEY12_14155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_14165	COG3279	Response regulator of the LytR AlgR family
CEY12_14170	COG3275	phosphorelay sensor kinase activity
CEY12_14175	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEY12_14175	COG2755	lipolytic protein G-D-S-L family
CEY12_14185	COG2807	transmembrane transport
CEY12_14195	COG2169	Transcriptional regulator
CEY12_14255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEY12_14260	COG0697	spore germination
CEY12_14280	COG0604	alcohol dehydrogenase
CEY12_14290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEY12_14340	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CEY12_14345	COG1397	ADP-ribosylglycohydrolase
CEY12_14350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEY12_14400	COG0494	nUDIX hydrolase
CEY12_14425	COG0481	GTPase activity
CEY12_14460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEY12_14465	COG0424	maF-like protein
CEY12_14475	COG1214	PFAM Peptidase M22, glycoprotease
CEY12_14480	COG4221	oxidoreductase activity
CEY12_14485	COG0792	nuclease activity
CEY12_14490	COG1619	proteins homologs of microcin C7 resistance protein MccF
CEY12_14500	COG0557	exoribonuclease II activity
CEY12_14505	COG0698	ribose 5-phosphate isomerase
CEY12_14510	COG0126	phosphoglycerate kinase activity
CEY12_14525	COG0445	tRNA wobble uridine modification
CEY12_14530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEY12_14540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEY12_14545	COG1435	thymidine kinase activity
CEY12_14555	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEY12_14565	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_14570	COG0516	GMP reductase activity
CEY12_14595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEY12_14600	COG0793	Belongs to the peptidase S41A family
CEY12_14605	COG2032	superoxide dismutase activity
CEY12_14610	COG4977	sequence-specific DNA binding
CEY12_14625	COG3275	phosphorelay sensor kinase activity
CEY12_14650	COG3279	Response regulator of the LytR AlgR family
CEY12_14680	COG0482	sulfurtransferase activity
CEY12_14690	COG0542	response to heat
CEY12_14705	COG2166	iron-sulfur cluster assembly
CEY12_14740	COG0285	dihydrofolate synthase activity
CEY12_14755	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CEY12_14755	COG0662	Cupin 2, conserved barrel domain protein
CEY12_14770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEY12_14775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEY12_14795	COG0811	peptide transport
CEY12_14815	COG2715	membrane protein required for spore maturation
CEY12_14825	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEY12_14835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEY12_14860	COG3781	membrane
CEY12_14870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEY12_14875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEY12_14910	COG2081	HI0933 family
CEY12_14920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEY12_14930	COG3279	Response regulator of the LytR AlgR family
CEY12_14935	COG3275	phosphorelay sensor kinase activity
CEY12_14955	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEY12_14970	COG2151	metal-sulfur cluster biosynthetic enzyme
CEY12_14980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEY12_15005	COG1595	DNA-templated transcription, initiation
CEY12_15020	COG0606	chelatase, subunit chli
CEY12_15055	COG3591	Belongs to the peptidase S1B family
CEY12_15085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEY12_15090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEY12_15115	COG0387	Pfam Sodium calcium exchanger
CEY12_15150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEY12_15150	COG0758	DNA mediated transformation
CEY12_15165	COG0719	Fe-S assembly protein
CEY12_15170	COG0396	ATPase activity
CEY12_15180	COG0719	Fe-S assembly protein
CEY12_15185	COG0316	Belongs to the HesB IscA family
CEY12_15200	COG2321	neutral zinc metallopeptidase
CEY12_15205	COG1368	sulfuric ester hydrolase activity
CEY12_15210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEY12_15220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEY12_15255	COG0437	4 iron, 4 sulfur cluster binding
CEY12_15280	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEY12_15295	COG1774	PSP1 C-terminal conserved region
CEY12_15310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEY12_15315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEY12_15335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEY12_15345	COG0181	hydroxymethylbilane synthase activity
CEY12_15350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEY12_15370	COG0768	penicillin binding
CEY12_15375	COG0772	Belongs to the SEDS family
CEY12_15385	COG0791	NLP P60 protein
CEY12_15390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_15405	COG5002	protein histidine kinase activity
CEY12_15410	COG0745	RESPONSE REGULATOR receiver
CEY12_15450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEY12_15460	COG0590	tRNA wobble adenosine to inosine editing
CEY12_15500	COG1876	peptidase activity
CEY12_15520	COG0423	glycine-tRNA ligase activity
CEY12_15525	COG0564	pseudouridine synthase activity
CEY12_15530	COG0167	dihydroorotate dehydrogenase activity
CEY12_15540	COG2733	membrane
CEY12_15545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEY12_15565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEY12_15575	COG0183	Belongs to the thiolase family
CEY12_15580	COG1309	transcriptional regulator
CEY12_15590	COG1764	response to oxidative stress
CEY12_15595	COG2169	Transcriptional regulator
CEY12_15615	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CEY12_15620	COG3537	Alpha-1,2-mannosidase
CEY12_15655	COG1082	Xylose isomerase domain protein TIM barrel
CEY12_15660	COG2814	Major facilitator Superfamily
CEY12_15670	COG1940	carbohydrate kinase activity
CEY12_15680	COG2186	Transcriptional regulator
CEY12_15725	COG1770	oligopeptidase
CEY12_15740	COG0463	Glycosyl transferase, family 2
CEY12_15750	COG0343	queuine tRNA-ribosyltransferase activity
CEY12_15760	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEY12_15760	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEY12_15765	COG0799	negative regulation of ribosome biogenesis
CEY12_15770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEY12_15780	COG4589	Belongs to the CDS family
CEY12_15785	COG0688	phosphatidylethanolamine metabolic process
CEY12_15810	COG1132	(ABC) transporter
CEY12_15830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEY12_15860	COG1611	Belongs to the LOG family
CEY12_15865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEY12_15870	COG1660	Displays ATPase and GTPase activities
CEY12_15895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEY12_15905	COG4772	TonB-dependent receptor
CEY12_15910	COG0157	Belongs to the NadC ModD family
CEY12_15915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEY12_15920	COG0778	Nitroreductase
CEY12_15940	COG0328	RNA-DNA hybrid ribonuclease activity
CEY12_15945	COG0305	Participates in initiation and elongation during chromosome replication
CEY12_15990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEY12_16015	COG0193	aminoacyl-tRNA hydrolase activity
CEY12_16030	COG0659	secondary active sulfate transmembrane transporter activity
CEY12_16040	COG0288	reversible hydration of carbon dioxide
CEY12_16045	COG0110	maltose O-acetyltransferase activity
CEY12_16070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEY12_16095	COG0463	Glycosyl transferase, family 2
CEY12_16100	COG1216	Glycosyl transferase, family 2
CEY12_16100	COG0463	Glycosyl transferase, family 2
CEY12_16105	COG1216	Glycosyl transferase, family 2
CEY12_16105	COG0463	Glycosyl transferase, family 2
CEY12_16110	COG0367	asparagine synthase
CEY12_16135	COG0463	Glycosyl transferase, family 2
CEY12_16145	COG1216	Glycosyl transferase, family 2
CEY12_16185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CEY12_16190	COG0779	Required for maturation of 30S ribosomal subunits
CEY12_16195	COG0195	Participates in both transcription termination and antitermination
CEY12_16200	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEY12_16205	COG1629	transport
CEY12_16205	COG4206	TonB-dependent receptor
CEY12_16225	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CEY12_16245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEY12_16250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEY12_16255	COG4206	TonB-dependent receptor
CEY12_16255	COG1629	transport
CEY12_16300	COG3781	membrane
CEY12_16315	COG2217	Heavy metal translocating P-type atpase
CEY12_16330	COG1999	signal sequence binding
CEY12_16335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEY12_16360	COG4206	TonB-dependent receptor
CEY12_16385	COG2223	nitrite transmembrane transporter activity
CEY12_16390	COG2186	Transcriptional regulator
CEY12_16435	COG0268	Binds directly to 16S ribosomal RNA
CEY12_16450	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEY12_16460	COG0251	oxidation-reduction process
CEY12_16470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEY12_16500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEY12_16510	COG3279	Response regulator of the LytR AlgR family
CEY12_16575	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEY12_16580	COG0783	Belongs to the Dps family
CEY12_16585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEY12_16590	COG0049	tRNA binding
CEY12_16595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEY12_16600	COG0051	transcription antitermination factor activity, RNA binding
CEY12_16610	COG4771	TonB-dependent receptor
CEY12_16640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEY12_16645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEY12_16650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEY12_16655	COG1349	DNA-binding transcription factor activity
CEY12_16660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEY12_16665	COG0088	Forms part of the polypeptide exit tunnel
CEY12_16670	COG0089	rRNA binding
CEY12_16675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEY12_16680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEY12_16685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEY12_16690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEY12_16695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEY12_16700	COG0255	Belongs to the universal ribosomal protein uL29 family
CEY12_16705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEY12_16710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEY12_16715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEY12_16720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEY12_16725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEY12_16730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEY12_16735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEY12_16740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEY12_16745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEY12_16750	COG1841	ribosomal large subunit assembly
CEY12_16755	COG0200	Binds to the 23S rRNA
CEY12_16765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEY12_16770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEY12_16775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEY12_16780	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEY12_16785	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEY12_16790	COG0202	RNA polymerase activity
CEY12_16795	COG0203	ribosomal protein L17
CEY12_16810	COG2197	response regulator
CEY12_16825	COG4585	Histidine kinase
CEY12_16845	COG0148	phosphopyruvate hydratase activity
CEY12_16865	COG1834	amidinotransferase
CEY12_16915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEY12_16925	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CEY12_16925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEY12_16940	COG0501	Belongs to the peptidase M48B family
CEY12_16945	COG3275	phosphorelay sensor kinase activity
CEY12_16960	COG0488	(ABC) transporter
CEY12_16965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEY12_16970	COG2885	chlorophyll binding
CEY12_16975	COG0217	transcriptional regulatory protein
CEY12_17020	COG0714	Associated with various cellular activities
CEY12_17045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEY12_17050	COG0527	aspartate kinase activity
CEY12_17050	COG0460	homoserine dehydrogenase
CEY12_17060	COG0646	methionine synthase
CEY12_17060	COG1410	methionine synthase
CEY12_17070	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEY12_17080	COG0302	gtp cyclohydrolase
CEY12_17090	COG0215	cysteine-tRNA ligase activity
CEY12_17100	COG1640	4-alpha-glucanotransferase
CEY12_17115	COG1528	Iron-storage protein
CEY12_17175	COG1074	ATP-dependent DNA helicase activity
CEY12_17215	COG0438	transferase activity, transferring glycosyl groups
CEY12_17220	COG1472	Belongs to the glycosyl hydrolase 3 family
CEY12_17230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEY12_17245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEY12_17260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEY12_17270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEY12_17275	COG3537	Alpha-1,2-mannosidase
CEY12_17295	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_17350	COG4585	Histidine kinase
CEY12_17370	COG0542	response to heat
CEY12_17375	COG1309	transcriptional regulator
CEY12_17380	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CEY12_17385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEY12_17390	COG3396	Phenylacetate-CoA oxygenase
CEY12_17400	COG3460	Phenylacetate-CoA oxygenase
CEY12_17410	COG2151	metal-sulfur cluster biosynthetic enzyme
CEY12_17415	COG1024	Enoyl-CoA hydratase
CEY12_17420	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEY12_17435	COG0183	Belongs to the thiolase family
CEY12_17455	COG2030	dehydratase
CEY12_17455	COG1012	belongs to the aldehyde dehydrogenase family
CEY12_17505	COG1408	metallophosphoesterase
CEY12_17530	COG1404	Belongs to the peptidase S8 family
CEY12_17530	COG4935	Belongs to the peptidase S8 family
CEY12_17535	COG1490	D-aminoacyl-tRNA deacylase activity
CEY12_17545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEY12_17550	COG0537	adenosine 5'-monophosphoramidase activity
CEY12_17555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEY12_17630	COG0281	malic enzyme
CEY12_17630	COG0280	phosphate acetyltransferase
CEY12_17635	COG0632	four-way junction helicase activity
CEY12_17645	COG0509	glycine decarboxylation via glycine cleavage system
CEY12_17725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CEY12_17750	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CEY12_17770	COG0322	excinuclease ABC activity
CEY12_17780	COG2986	histidine ammonia-lyase
CEY12_17795	COG1404	Belongs to the peptidase S8 family
CEY12_17805	COG3384	dioxygenase
CEY12_17810	COG2353	YceI-like domain
CEY12_17815	COG0823	Involved in the tonB-independent uptake of proteins
CEY12_17815	COG1506	peptidase
CEY12_17825	COG0419	ATPase involved in DNA repair
CEY12_17830	COG0420	3'-5' exonuclease activity
CEY12_17835	COG4628	conserved protein (DUF2132)
CEY12_17840	COG1047	Peptidyl-prolyl cis-trans
CEY12_17845	COG3012	SEC-C Motif Domain Protein
CEY12_17850	COG0339	signal peptide processing
CEY12_17880	COG1704	LemA family
CEY12_17885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEY12_17915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEY12_17920	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEY12_17930	COG0564	pseudouridine synthase activity
CEY12_17940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEY12_17950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEY12_17955	COG0778	Nitroreductase
CEY12_17960	COG1733	regulation of RNA biosynthetic process
CEY12_17985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEY12_18000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEY12_18005	COG0242	peptide deformylase activity
CEY12_18015	COG3956	TIGRFAM MazG family protein
CEY12_18040	COG3781	membrane
CEY12_18050	COG1007	ATP synthesis coupled electron transport
CEY12_18055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEY12_18060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEY12_18070	COG0839	Belongs to the complex I subunit 6 family
CEY12_18075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEY12_18080	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CEY12_18085	COG1034	ATP synthesis coupled electron transport
CEY12_18095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEY12_18100	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CEY12_18105	COG0649	NAD binding
CEY12_18110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEY12_18115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEY12_18120	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEY12_18140	COG1739	Uncharacterized protein family UPF0029
CEY12_18145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEY12_18145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEY12_18155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEY12_18170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEY12_18175	COG0346	lactoylglutathione lyase activity
CEY12_18210	COG1505	serine-type exopeptidase activity
CEY12_18245	COG0024	Methionine aminopeptidase
CEY12_18285	COG3620	sequence-specific DNA binding
CEY12_18305	COG0813	purine-nucleoside phosphorylase activity
CEY12_18320	COG0714	Associated with various cellular activities
CEY12_18410	COG2267	carboxylic ester hydrolase activity
CEY12_18450	COG0659	secondary active sulfate transmembrane transporter activity
CEY12_18455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEY12_18470	COG2310	stress, protein
CEY12_18475	COG3853	Toxic anion resistance protein (TelA)
CEY12_18510	COG1959	2 iron, 2 sulfur cluster binding
CEY12_18515	COG2910	NAD(P)H-binding
CEY12_18525	COG0739	heme binding
CEY12_18530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEY12_18535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEY12_18545	COG0579	oxidoreductase
CEY12_18595	COG0737	Belongs to the 5'-nucleotidase family
CEY12_18600	COG0737	Belongs to the 5'-nucleotidase family
CEY12_18605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEY12_18630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEY12_18640	COG4232	protein-disulfide reductase activity
CEY12_18645	COG3104	oligopeptide transport
CEY12_18650	COG3104	oligopeptide transport
CEY12_18665	COG1506	peptidase
CEY12_18665	COG0823	Involved in the tonB-independent uptake of proteins
CEY12_18700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEY12_18705	COG0069	glutamate synthase activity
CEY12_18715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEY12_18720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEY12_18740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEY12_18755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEY12_18760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEY12_18785	COG4095	Psort location CytoplasmicMembrane, score
CEY12_18815	COG1538	Outer membrane efflux protein
CEY12_18830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEY12_18845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEY12_18865	COG0252	asparaginase activity
CEY12_18875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEY12_18885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEY12_18895	COG1522	sequence-specific DNA binding
CEY12_18905	COG1309	transcriptional regulator
CEY12_18915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEY12_18925	COG3959	Transketolase, thiamine diphosphate binding domain
CEY12_18935	COG4145	pantothenate transmembrane transporter activity
CEY12_18940	COG2388	GCN5-related N-acetyl-transferase
CEY12_18960	COG0431	NADPH-dependent FMN reductase
CEY12_18965	COG1741	Belongs to the pirin family
CEY12_18980	COG0477	Major facilitator Superfamily
CEY12_18990	COG0367	asparagine synthase
CEY12_19000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEY12_19000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEY12_19005	COG2824	Alkylphosphonate utilization operon protein PhnA
CEY12_19015	COG3842	ATPase activity
CEY12_19025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEY12_19035	COG0492	ferredoxin-NADP+ reductase activity
CEY12_19050	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEY12_19065	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEY12_19080	COG0612	Peptidase, M16
CEY12_19085	COG0612	Peptidase, M16
CEY12_19095	COG4771	TonB-dependent receptor
CEY12_19100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEY12_19105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CEY12_19110	COG0352	thiamine-phosphate diphosphorylase activity
CEY12_19110	COG0351	phosphomethylpyrimidine kinase
CEY12_19115	COG0352	thiamine-phosphate diphosphorylase activity
CEY12_19120	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CEY12_19125	COG1966	Carbon starvation protein
CEY12_19150	COG1917	Cupin 2, conserved barrel domain protein
CEY12_19150	COG2207	Transcriptional regulator
CEY12_19160	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CEY12_19165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEY12_19185	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CEY12_19195	COG0427	acetyl-CoA hydrolase
CEY12_19200	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEY12_19205	COG4771	TonB-dependent receptor
CEY12_19225	COG1733	regulation of RNA biosynthetic process
CEY12_19245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEY12_19255	COG0667	Aldo Keto reductase
CEY12_19275	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEY12_19300	COG0583	DNA-binding transcription factor activity
CEY12_19310	COG0519	Catalyzes the synthesis of GMP from XMP
CEY12_19315	COG0656	L-ascorbic acid biosynthetic process
CEY12_19320	COG2070	2-Nitropropane dioxygenase
CEY12_19330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEY12_19355	COG1530	ribonuclease E activity
CEY12_19360	COG0776	regulation of translation
CEY12_19365	COG2197	response regulator
CEY12_19395	COG0542	response to heat
CEY12_19410	COG3501	Rhs element vgr protein
CEY12_19455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEY12_19455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEY12_19505	COG3433	isochorismatase activity
CEY12_19505	COG1535	isochorismatase
CEY12_19560	COG2205	protein histidine kinase activity
CEY12_19570	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CEY12_19580	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CEY12_19590	COG2204	response regulator
CEY12_19600	COG0612	Peptidase, M16
CEY12_19640	COG4717	serine-type aminopeptidase activity
CEY12_19650	COG1285	pathogenesis
CEY12_19655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEY12_19685	COG0300	oxidoreductase activity
CEY12_19690	COG2264	protein methyltransferase activity
CEY12_19750	COG3023	N-Acetylmuramoyl-L-alanine amidase
CEY12_19755	COG1027	Aspartate ammonia-lyase
CEY12_19760	COG1442	glycosyl transferase family 8
CEY12_19760	COG1216	Glycosyl transferase, family 2
CEY12_19785	COG1136	(ABC) transporter
CEY12_19785	COG0577	efflux transmembrane transporter activity
CEY12_19790	COG1136	(ABC) transporter
CEY12_19795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEY12_19815	COG0306	phosphate transporter
CEY12_19835	COG0084	hydrolase, TatD family'
CEY12_19840	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEY12_19840	COG2755	lipolytic protein G-D-S-L family
CEY12_19845	COG0513	Belongs to the DEAD box helicase family
CEY12_19860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEY12_19865	COG0563	adenylate kinase activity
CEY12_19890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEY12_19915	COG1192	Involved in chromosome partitioning
CEY12_19920	COG1475	DNA binding
CEY12_19930	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEY12_19935	COG0681	Belongs to the peptidase S26 family
CEY12_19960	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CEY12_19965	COG0277	FAD linked oxidase domain protein
CEY12_19975	COG0560	Phosphoserine phosphatase
CEY12_19985	COG1104	cysteine desulfurase activity
CEY12_20010	COG3665	Urea carboxylase-associated protein
CEY12_20045	COG3409	Peptidoglycan-binding domain 1 protein
CEY12_20045	COG0793	Belongs to the peptidase S41A family
CEY12_20060	COG2197	response regulator
CEY12_20100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEY12_20115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEY12_20120	COG1917	Cupin 2, conserved barrel domain protein
CEY12_20120	COG2207	Transcriptional regulator
CEY12_20125	COG2814	Major facilitator Superfamily
CEY12_20135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEY12_20135	COG0723	plastoquinol--plastocyanin reductase activity
CEY12_20155	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CEY12_20160	COG3275	phosphorelay sensor kinase activity
CEY12_20170	COG3279	Response regulator of the LytR AlgR family
CEY12_20180	COG1546	Belongs to the CinA family
CEY12_20180	COG1058	Belongs to the CinA family
CEY12_20190	COG3590	peptidase
CEY12_20195	COG3590	peptidase
CEY12_20245	COG2267	carboxylic ester hydrolase activity
CEY12_20265	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEY12_20320	COG0513	Belongs to the DEAD box helicase family
CEY12_20340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEY12_20390	COG2079	MmgE PrpD family protein
CEY12_20400	COG1960	acyl-CoA dehydrogenase activity
CEY12_20405	COG1024	Enoyl-CoA hydratase
CEY12_20415	COG1024	Enoyl-CoA hydratase
CEY12_20445	COG1309	transcriptional regulator
CEY12_20450	COG0477	Major facilitator Superfamily
CEY12_20455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEY12_20495	COG0513	Belongs to the DEAD box helicase family
CEY12_20500	COG1278	Cold shock
CEY12_20510	COG0387	Pfam Sodium calcium exchanger
CEY12_20565	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_20615	COG1733	regulation of RNA biosynthetic process
CEY12_20620	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_20635	COG4221	oxidoreductase activity
CEY12_20640	COG1733	regulation of RNA biosynthetic process
CEY12_20645	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_20795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEY12_20810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEY12_20810	COG0321	lipoyl(octanoyl) transferase activity
CEY12_20825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEY12_20830	COG2239	Acts as a magnesium transporter
CEY12_20840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEY12_20850	COG1185	polyribonucleotide nucleotidyltransferase activity
CEY12_20860	COG1131	(ABC) transporter
CEY12_20865	COG3655	Transcriptional regulator
CEY12_20880	COG3541	Predicted nucleotidyltransferase
CEY12_20915	COG0837	glucose binding
CEY12_20935	COG0004	ammonium transporteR
CEY12_20940	COG1760	l-serine dehydratase
CEY12_20945	COG0287	Prephenate dehydrogenase
CEY12_20960	COG0475	glutathione-regulated potassium exporter activity
CEY12_20970	COG3279	Response regulator of the LytR AlgR family
CEY12_20985	COG0686	Belongs to the AlaDH PNT family
CEY12_20990	COG0802	atpase or kinase
CEY12_21005	COG0358	DNA primase activity
CEY12_21025	COG0149	triose-phosphate isomerase activity
CEY12_21055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEY12_21075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEY12_21080	COG1595	DNA-templated transcription, initiation
CEY12_21110	COG1131	(ABC) transporter
CEY12_21115	COG1222	aaa ATPase
CEY12_21125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CEY12_21130	COG0586	Pfam SNARE associated Golgi protein
CEY12_21155	COG2354	Protein conserved in bacteria
CEY12_21170	COG0484	heat shock protein binding
CEY12_21175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEY12_21190	COG0442	prolyl-tRNA aminoacylation
CEY12_21210	COG4206	TonB-dependent receptor
CEY12_21210	COG1629	transport
CEY12_21225	COG0116	Belongs to the methyltransferase superfamily
CEY12_21250	COG0463	Glycosyl transferase, family 2
CEY12_21255	COG0626	cystathionine gamma-synthase activity
CEY12_21265	COG3781	membrane
CEY12_21270	COG0022	dehydrogenase e1 component
CEY12_21275	COG0587	DNA-directed DNA polymerase activity
CEY12_21295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEY12_21300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEY12_21315	COG1960	acyl-CoA dehydrogenase activity
CEY12_21325	COG2140	Oxalate decarboxylase
CEY12_21345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEY12_21350	COG1234	tRNA 3'-trailer cleavage
CEY12_21380	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEY12_21385	COG2177	Part of the ABC transporter FtsEX involved in
CEY12_21395	COG1968	undecaprenyl-diphosphatase activity
CEY12_21405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEY12_21410	COG1187	pseudouridine synthase activity
CEY12_21435	COG0348	domain, Protein
CEY12_21450	COG0513	Belongs to the DEAD box helicase family
CEY12_21455	COG0539	negative regulation of cytoplasmic translation
CEY12_21455	COG2183	response to ionizing radiation
CEY12_21475	COG2311	Membrane
CEY12_21485	COG0335	large ribosomal subunit rRNA binding
CEY12_21520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CEY12_21525	COG1132	(ABC) transporter
CEY12_21540	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CEY12_21545	COG1446	asparaginase
CEY12_21550	COG3142	Participates in the control of copper homeostasis
CEY12_21560	COG0679	Auxin Efflux Carrier
CEY12_21575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEY12_21640	COG0156	8-amino-7-oxononanoate synthase activity
CEY12_21680	COG4221	oxidoreductase activity
CEY12_21695	COG4221	oxidoreductase activity
CEY12_21710	COG1959	2 iron, 2 sulfur cluster binding
CEY12_21750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEY12_21755	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEY12_21765	COG3720	iron ion transport
CEY12_21775	COG0242	peptide deformylase activity
CEY12_21785	COG1846	Transcriptional regulator
CEY12_21790	COG0778	Nitroreductase
CEY12_21800	COG1028	Short-chain dehydrogenase reductase Sdr
CEY12_21825	COG0321	lipoyl(octanoyl) transferase activity
CEY12_21830	COG0159	tryptophan synthase activity
CEY12_21835	COG0133	tryptophan synthase activity
CEY12_21850	COG0135	phosphoribosylanthranilate isomerase activity
CEY12_21855	COG0134	indole-3-glycerol-phosphate synthase activity
CEY12_21860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEY12_21865	COG0512	Glutamine amidotransferase of anthranilate synthase
CEY12_21865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEY12_21870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEY12_21885	COG4654	Cytochrome c, class I
CEY12_21890	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CEY12_21895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEY12_21910	COG1271	oxidase subunit
CEY12_21915	COG0187	DNA topoisomerase II activity
CEY12_21945	COG1301	dicarboxylic acid transport
CEY12_21950	COG0405	Gamma-glutamyltransferase
CEY12_21960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEY12_21970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEY12_21975	COG1408	metallophosphoesterase
CEY12_21980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEY12_21990	COG2226	methyltransferase
CEY12_22010	COG1418	mRNA catabolic process
CEY12_22015	COG0477	Major facilitator Superfamily
CEY12_22025	COG2855	membrane
CEY12_22030	COG0583	DNA-binding transcription factor activity
CEY12_22035	COG0038	chloride channel
CEY12_22045	COG1607	acyl-coa hydrolase
CEY12_22080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEY12_22090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CEY12_22100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEY12_22110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEY12_22115	COG1970	mechanosensitive ion channel activity
CEY12_22120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEY12_22125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEY12_22135	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEY12_22155	COG0077	Prephenate dehydratase