locus-tag	class	description
EJF16_10006	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
EJF16_10016	ENOG4105D9P	serine threonine protein kinase
EJF16_10019	ENOG4105CSP	Major Facilitator Superfamily
EJF16_10021	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EJF16_10022	ENOG4105E0X	reductase
EJF16_10027	ENOG4108IQI	permease
EJF16_10031	ENOG4105CTZ	aminopeptidase c
EJF16_10051	ENOG4105D9P	serine threonine protein kinase
EJF16_10052	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EJF16_10053	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EJF16_10060	ENOG4105D1F	ATP-binding protein
EJF16_10097	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EJF16_10109	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EJF16_10125	ENOG4107R16	Multicopper oxidase
EJF16_10135	ENOG4105BZ1	(ABC) transporter
EJF16_10153	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
EJF16_10158	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EJF16_10168	ENOG4105CA9	Pyruvate kinase
EJF16_10169	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EJF16_10177	ENOG4108IQI	permease
EJF16_10182	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
EJF16_10185	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EJF16_10190	ENOG4105CJQ	hydrolase, family 31
EJF16_10197	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EJF16_10200	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EJF16_10201	ENOG4105D9P	serine threonine protein kinase
EJF16_10218	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EJF16_10233	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
EJF16_10236	ENOG4108UW5	maltose o-acetyltransferase
EJF16_10237	ENOG4105CV8	reductase
EJF16_10244	ENOG4105VFU	Rna-binding protein
EJF16_10246	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EJF16_10247	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_10254	ENOG4105CQB	FAD linked oxidase domain protein
EJF16_10255	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EJF16_10273	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EJF16_10279	ENOG4105CHR	reductase
EJF16_10286	ENOG4105C8Y	Acetylornithine aminotransferase
EJF16_10290	ENOG4108IQK	o-acetylhomoserine
EJF16_10304	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EJF16_10307	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_10324	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
EJF16_10325	ENOG4105CVJ	phosphoglycerate mutase
EJF16_10346	ENOG4105KZX	Pterin carbinolamine dehydratase
EJF16_10348	ENOG4105CQ7	ATP-dependent helicase
EJF16_10357	ENOG4105CJ3	phosphate transporter
EJF16_10363	ENOG4105C1J	atp-dependent rna helicase
EJF16_10368	ENOG4108IQI	permease
EJF16_10382	ENOG4108URH	decarboxylase
EJF16_10383	ENOG41077A9	carbonic anhydrase
EJF16_10385	ENOG4105C0D	helicase
EJF16_10390	ENOG4105CHR	reductase
EJF16_10401	ENOG4105CRQ	synthase (Component I)
EJF16_10416	ENOG4105CUZ	uba thif-type nad fad binding protein
EJF16_10422	ENOG4105CSP	Major Facilitator Superfamily
EJF16_10423	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EJF16_10424	ENOG4105C54	Major Facilitator superfamily
EJF16_10427	ENOG4105C54	Major Facilitator superfamily
EJF16_10428	ENOG4107QNK	)-transporter
EJF16_10429	ENOG4105CGF	Aromatic amino acid aminotransferase
EJF16_10430	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
EJF16_10434	ENOG4108YBP	pseudouridine synthase
EJF16_10435	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EJF16_10438	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EJF16_10444	ENOG4105CHH	sulfate transporter
EJF16_10453	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EJF16_10460	ENOG4108IQI	permease
EJF16_10461	ENOG4107R5B	glutamine synthetase
EJF16_10485	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EJF16_10486	ENOG4105CV8	reductase
EJF16_10502	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EJF16_10514	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EJF16_10516	ENOG4105D2S	major facilitator superfamily
EJF16_10521	ENOG4105F0N	pyrophosphate phospho-hydrolase
EJF16_10526	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EJF16_10538	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EJF16_10567	ENOG4105DDQ	anthranilate synthase
EJF16_10586	ENOG4105D9P	serine threonine protein kinase
EJF16_10606	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EJF16_10609	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EJF16_10611	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EJF16_10618	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EJF16_10620	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EJF16_10628	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EJF16_10639	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EJF16_10651	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EJF16_10669	ENOG4106HK8	GPR1 FUN34 yaaH family protein
EJF16_10672	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EJF16_10675	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EJF16_10690	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EJF16_10692	ENOG4108IQI	permease
EJF16_10693	ENOG4108IGT	Dipeptidase
EJF16_10720	ENOG4105CHR	reductase
EJF16_10731	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EJF16_10738	ENOG4105CQ7	ATP-dependent helicase
EJF16_10746	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EJF16_10747	ENOG410870F	Cyclic nucleotide-binding protein
EJF16_10751	ENOG4108I0Z	Aconitate hydratase
EJF16_10766	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
EJF16_10770	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
EJF16_10780	ENOG4108IQI	permease
EJF16_10781	ENOG4108IQI	permease
EJF16_10783	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
EJF16_10787	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
EJF16_10794	ENOG4105C1V	Peptidase, M16
EJF16_10800	ENOG4108AMH	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
EJF16_10807	ENOG4105C28	cystathionine
EJF16_10810	ENOG4105DC7	peptidase M24
EJF16_10811	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
EJF16_10827	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EJF16_10845	ENOG4105D6Z	AFG1 family ATPase
EJF16_10849	ENOG41090KN	UPF0303 protein
EJF16_10855	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EJF16_10877	ENOG4108UGD	Serine Threonine protein kinase
EJF16_10881	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EJF16_10891	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EJF16_10901	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EJF16_10915	ENOG4107QNK	)-transporter
EJF16_10918	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
EJF16_10922	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EJF16_10931	ENOG4107WDG	serine threonine protein kinase
EJF16_10941	ENOG4105D9P	serine threonine protein kinase
EJF16_10952	ENOG4105C5S	asparaginyl-tRNA synthetase
EJF16_10955	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EJF16_10980	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EJF16_10985	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EJF16_10995	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EJF16_10999	ENOG4107QI1	Mate efflux family protein
EJF16_11002	ENOG4105CV8	reductase
EJF16_11010	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EJF16_11012	ENOG4107RA9	decarboxylase
EJF16_11018	ENOG4107TPY	serine threonine protein kinase
EJF16_11024	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EJF16_11026	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
EJF16_11029	ENOG4105BZ1	(ABC) transporter
EJF16_11033	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EJF16_11042	ENOG4105DMF	Dehydrogenase
EJF16_11048	ENOG4107QNK	)-transporter
EJF16_11058	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EJF16_11062	ENOG4105D6Z	AFG1 family ATPase
EJF16_11066	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
EJF16_11076	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
EJF16_11079	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EJF16_11082	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
EJF16_11085	ENOG4107RA9	decarboxylase
EJF16_11090	ENOG4105DJV	ribulose-phosphate 3-epimerase
EJF16_11097	ENOG4105C0D	helicase
EJF16_11104	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EJF16_11110	ENOG4107EFR	Flavocytochrome c
EJF16_11113	ENOG4105CTZ	aminopeptidase c
EJF16_11118	ENOG4105CDY	transcriptional regulatory protein
EJF16_11120	ENOG4105C8Y	Acetylornithine aminotransferase
EJF16_11125	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
EJF16_11127	ENOG4105CUB	amino acid
EJF16_11141	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EJF16_11155	ENOG4108QVN	serine threonine protein kinase
EJF16_11157	ENOG4107QK5	Homocysteine s-methyltransferase
EJF16_11159	ENOG4105CIG	ABC transporter
EJF16_11161	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EJF16_11169	ENOG4107QP8	phosphohexose isomerase
EJF16_11173	ENOG41076HS	cation diffusion facilitator family transporter
EJF16_11185	ENOG4105CUT	histidyl-tRNA synthetase
EJF16_11197	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EJF16_11206	ENOG4107QNK	)-transporter
EJF16_11207	ENOG4107QNK	)-transporter
EJF16_11209	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
EJF16_11220	ENOG4107RAQ	aminopeptidase
EJF16_20003	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EJF16_20010	ENOG4108JZA	Homocitrate synthase
EJF16_20012	ENOG4105EV9	Alpha Beta Hydrolase
EJF16_20018	ENOG4105CD8	aminopeptidase N
EJF16_20020	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
EJF16_20021	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EJF16_20027	ENOG4105FDK	ABC transporter
EJF16_20031	ENOG4105W0E	50S ribosomal protein L33
EJF16_20039	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EJF16_20044	ENOG4105D9P	serine threonine protein kinase
EJF16_20061	ENOG4105DC8	reductase
EJF16_20065	ENOG4105CSH	Transporter
EJF16_20066	ENOG4107QP3	malate synthase g
EJF16_20068	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EJF16_20073	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EJF16_20084	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
EJF16_20085	ENOG4105C1J	atp-dependent rna helicase
EJF16_20091	ENOG4105D9P	serine threonine protein kinase
EJF16_20095	ENOG4105DMQ	Methyltransferase
EJF16_20102	ENOG4105EKE	dihydroorotase
EJF16_20124	ENOG4105DY8	decarboxylase
EJF16_20135	ENOG4105DGU	Histone deacetylase
EJF16_20138	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
EJF16_20140	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
EJF16_20154	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
EJF16_20155	ENOG4105EV9	Alpha Beta Hydrolase
EJF16_20161	ENOG4106CJB	Phospholipase Carboxylesterase
EJF16_20169	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EJF16_20173	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EJF16_20177	ENOG4105D9P	serine threonine protein kinase
EJF16_20179	ENOG4107TH8	cina domain protein
EJF16_20183	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_20185	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EJF16_20191	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EJF16_20204	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EJF16_20215	ENOG4105KME	endoribonuclease L-psp
EJF16_20238	ENOG4105CQ7	ATP-dependent helicase
EJF16_20240	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EJF16_20241	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_20247	ENOG4108PBA	serine threonine protein kinase
EJF16_20259	ENOG4105D3R	alkyl hydroperoxide reductase
EJF16_20263	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EJF16_20272	ENOG4105CGF	Aromatic amino acid aminotransferase
EJF16_20274	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EJF16_20277	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EJF16_20281	ENOG4105C7S	Dehydrogenase
EJF16_20287	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EJF16_20291	ENOG4107QNK	)-transporter
EJF16_20295	ENOG4105CHM	Aminotransferase
EJF16_20297	ENOG4107QUV	Domain protein
EJF16_20303	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
EJF16_20307	ENOG4105CKI	cobalamin synthesis protein
EJF16_20311	ENOG41079KZ	Major Facilitator Superfamily
EJF16_20317	ENOG4108PBA	serine threonine protein kinase
EJF16_20326	ENOG4105K63	Thioredoxin
EJF16_20341	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EJF16_20345	ENOG4105D9P	serine threonine protein kinase
EJF16_20347	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EJF16_20352	ENOG4107R16	Multicopper oxidase
EJF16_20377	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EJF16_20386	ENOG4105CTM	Glycoside hydrolase family 5
EJF16_20387	ENOG4105CFH	Aspartokinase
EJF16_20392	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
EJF16_20393	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJF16_20414	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EJF16_20432	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EJF16_20440	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EJF16_20441	ENOG4105C1J	atp-dependent rna helicase
EJF16_20447	ENOG4105CH7	arginosuccinase
EJF16_20448	ENOG4105C5S	asparaginyl-tRNA synthetase
EJF16_20449	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EJF16_20451	ENOG4105C5S	asparaginyl-tRNA synthetase
EJF16_20456	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EJF16_20458	ENOG4105C85	amino acid
EJF16_20459	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
EJF16_20469	ENOG4105CKK	Glycosyl transferase, family 2
EJF16_20470	ENOG4107QN2	dihydrolipoyl dehydrogenase
EJF16_20472	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EJF16_20486	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EJF16_20495	ENOG4105CHR	reductase
EJF16_20506	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EJF16_20518	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EJF16_20534	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_20539	ENOG4105DGU	Histone deacetylase
EJF16_20540	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EJF16_20552	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EJF16_20554	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EJF16_20576	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EJF16_20578	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_20579	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EJF16_20582	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EJF16_20583	ENOG4105DJ4	phosphatidylserine decarboxylase
EJF16_20585	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EJF16_20586	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EJF16_20587	ENOG4105EUJ	GTP cyclohydrolase i
EJF16_20588	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EJF16_20597	ENOG4105CTQ	phosphohexokinase
EJF16_20605	ENOG4105C26	Dehydrogenase
EJF16_20607	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJF16_20609	ENOG4105CB5	ATP-dependent DNA helicase recG
EJF16_20622	ENOG4108QVN	serine threonine protein kinase
EJF16_20628	ENOG4105D9P	serine threonine protein kinase
EJF16_20629	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EJF16_20632	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
EJF16_20661	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EJF16_20662	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EJF16_20663	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EJF16_20670	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EJF16_20679	ENOG4105D52	delta-aminolevulinic acid dehydratase
EJF16_20682	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EJF16_20685	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
EJF16_20687	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EJF16_20688	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
EJF16_20690	ENOG4108IQI	permease
EJF16_20698	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EJF16_20701	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EJF16_20707	ENOG4105CSP	Major Facilitator Superfamily
EJF16_20724	ENOG4105DFM	M18 family aminopeptidase
EJF16_20745	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EJF16_20747	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EJF16_20755	ENOG4105C54	Major Facilitator superfamily
EJF16_20760	ENOG4105C4R	Atp-dependent dna helicase
EJF16_20764	ENOG4108ZP8	Acetolactate synthase small subunit
EJF16_20773	ENOG4105EF1	ribulokinase
EJF16_20789	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
EJF16_20795	ENOG4105BZ1	(ABC) transporter
EJF16_20803	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_20810	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_20814	ENOG4108IQI	permease
EJF16_20831	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EJF16_20839	ENOG4105CNG	UPF0061 protein
EJF16_20843	ENOG4105C0D	helicase
EJF16_20844	ENOG4106HK8	GPR1 FUN34 yaaH family protein
EJF16_20847	ENOG4108QVN	serine threonine protein kinase
EJF16_20850	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EJF16_20858	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EJF16_20878	ENOG4105C5H	ABC transporter
EJF16_20883	ENOG4105C26	Dehydrogenase
EJF16_20888	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
EJF16_20891	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EJF16_20896	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EJF16_20900	ENOG4105EMU	Dehydrogenase
EJF16_20904	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EJF16_20910	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
EJF16_20916	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EJF16_20918	ENOG4105D2N	Aldolase
EJF16_20924	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EJF16_20930	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EJF16_20931	ENOG4107TPY	serine threonine protein kinase
EJF16_20935	ENOG4105CHU	acetyl-coa acetyltransferase
EJF16_20940	ENOG4107TPY	serine threonine protein kinase
EJF16_20948	ENOG4105C0D	helicase
EJF16_20962	ENOG4105C1J	atp-dependent rna helicase
EJF16_20964	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EJF16_20968	ENOG4107QNK	)-transporter
EJF16_30002	ENOG4105ES4	Nitrilase
EJF16_30005	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EJF16_30010	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EJF16_30015	ENOG4108IQI	permease
EJF16_30021	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EJF16_30023	ENOG4105C1J	atp-dependent rna helicase
EJF16_30024	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EJF16_30027	ENOG4105C1J	atp-dependent rna helicase
EJF16_30035	ENOG4105C1J	atp-dependent rna helicase
EJF16_30038	ENOG4105CAS	nag kinase
EJF16_30045	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
EJF16_30051	ENOG4107YD0	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EJF16_30052	ENOG4108VZM	50s ribosomal protein L10
EJF16_30053	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EJF16_30066	ENOG4108JJB	ABC transporter
EJF16_30067	ENOG4105C0D	helicase
EJF16_30075	ENOG4105E39	Enoyl-CoA hydratase
EJF16_30078	ENOG41080RH	Thioredoxin
EJF16_30083	ENOG4105DWV	Homoserine O-trans-acetylase
EJF16_30085	ENOG4105BZ1	(ABC) transporter
EJF16_30093	ENOG4105CHR	reductase
EJF16_30103	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EJF16_30104	ENOG4108ETH	Formylglycinamide ribotide synthetase
EJF16_30117	ENOG4107RH7	Nicotinate phosphoribosyltransferase
EJF16_30119	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
EJF16_30122	ENOG4105EUF	amidase EC 3.5.1.4
EJF16_30126	ENOG4105C9M	aspartyl-trna synthetase
EJF16_30138	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
EJF16_30145	ENOG4105K63	Thioredoxin
EJF16_30147	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EJF16_30151	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EJF16_30164	ENOG4105BZ1	(ABC) transporter
EJF16_30165	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EJF16_30184	ENOG4108JQ1	Dehydrogenase
EJF16_30190	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EJF16_30210	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_30219	ENOG4105BZ1	(ABC) transporter
EJF16_30223	ENOG4105BZU	Histidine kinase
EJF16_30236	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EJF16_30239	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
EJF16_30262	ENOG4105C1J	atp-dependent rna helicase
EJF16_30268	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EJF16_30274	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EJF16_30287	ENOG4105PGM	cation diffusion facilitator family transporter
EJF16_30288	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_30290	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EJF16_30293	ENOG4107QYG	anthranilate phosphoribosyltransferase
EJF16_30295	ENOG4108JYK	Dehydrogenase
EJF16_30310	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EJF16_30315	ENOG4105CQR	helicase
EJF16_30326	ENOG4105R2D	cytochrome C
EJF16_30330	ENOG4105BZ1	(ABC) transporter
EJF16_30348	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
EJF16_30351	ENOG4105D9P	serine threonine protein kinase
EJF16_30356	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
EJF16_30358	ENOG4105CXK	mandelate racemase muconate lactonizing
EJF16_30359	ENOG4105DUX	Transporter
EJF16_30365	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EJF16_30370	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
EJF16_30371	ENOG4105CE4	GlcNAc 6-P deacetylase
EJF16_30373	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_30386	ENOG4105E2D	ec 3.2.1.52
EJF16_30393	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_30399	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EJF16_30400	ENOG4105CRK	lysyL-tRNA synthetase
EJF16_30407	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EJF16_30408	ENOG4105C7S	Dehydrogenase
EJF16_30410	ENOG4108Z03	MAF-like protein
EJF16_30420	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EJF16_30431	ENOG4105CVJ	phosphoglycerate mutase
EJF16_30435	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_30437	ENOG4105CQR	helicase
EJF16_30444	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_30447	ENOG4107QP3	malate synthase g
EJF16_30461	ENOG4105CQ7	ATP-dependent helicase
EJF16_30464	ENOG4105E66	phosphoriboisomerase A
EJF16_30476	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
EJF16_30477	ENOG4105C28	cystathionine
EJF16_30478	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EJF16_30479	ENOG4107QNK	)-transporter
EJF16_30495	ENOG4105C8T	Leucyl-tRNA synthetase
EJF16_30499	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EJF16_30512	ENOG4105C3G	gtp-binding protein
EJF16_30515	ENOG4107QHI	-hydrogenase
EJF16_30538	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EJF16_30547	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EJF16_30559	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
EJF16_30566	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EJF16_30569	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EJF16_30578	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EJF16_30588	ENOG4107QPV	Serine Threonine protein kinase
EJF16_30589	ENOG4107TPY	serine threonine protein kinase
EJF16_30593	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EJF16_30605	ENOG4105DFM	M18 family aminopeptidase
EJF16_30608	ENOG4105D9P	serine threonine protein kinase
EJF16_30612	ENOG4105BZU	Histidine kinase
EJF16_30613	ENOG4105C7K	acetolactate synthase
EJF16_30615	ENOG4105CPQ	Dehydrogenase
EJF16_30624	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EJF16_30632	ENOG4105D9P	serine threonine protein kinase
EJF16_30637	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EJF16_30648	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EJF16_30661	ENOG4105KNE	Phosphatidate cytidylyltransferase
EJF16_30664	ENOG4107QIZ	NADH dehydrogenase
EJF16_30672	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EJF16_30695	ENOG4105DFA	alanine racemase domain protein
EJF16_30699	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EJF16_30718	ENOG4105D9P	serine threonine protein kinase
EJF16_30724	ENOG4105C8Y	Acetylornithine aminotransferase
EJF16_30729	ENOG4105CPP	Dehydrogenase, E1 component
EJF16_30735	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
EJF16_30744	ENOG4105D1H	recombination factor protein RarA
EJF16_30746	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_30747	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_30749	ENOG4108JQ1	Dehydrogenase
EJF16_30756	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EJF16_30763	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_30789	ENOG4105VFU	Rna-binding protein
EJF16_30797	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
EJF16_30806	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
EJF16_30807	ENOG4105CKU	formyltetrahydrofolate synthetase
EJF16_30813	ENOG4105C1J	atp-dependent rna helicase
EJF16_30814	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJF16_30817	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EJF16_30831	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
EJF16_30835	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
EJF16_30846	ENOG4105DBI	uridine monophosphokinase
EJF16_30847	ENOG4105C1J	atp-dependent rna helicase
EJF16_30851	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EJF16_30868	ENOG4105VT2	5-hydroxyisourate hydrolase
EJF16_30873	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EJF16_30878	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EJF16_30881	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EJF16_30894	ENOG410633P	Hydantoin racemase
EJF16_30896	ENOG4105SYT	Methylenetetrahydrofolate reductase
EJF16_30907	ENOG4105D3G	Pseudouridine synthase
EJF16_30926	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EJF16_30929	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EJF16_30930	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EJF16_30931	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EJF16_30942	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_30945	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EJF16_30946	ENOG4105DC7	peptidase M24
EJF16_30949	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
EJF16_30951	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EJF16_30954	ENOG4105C6T	cysteine synthase
EJF16_30968	ENOG4105BZU	Histidine kinase
EJF16_40003	ENOG4105DQ4	alcohol dehydrogenase
EJF16_40004	ENOG4105DQ4	alcohol dehydrogenase
EJF16_40017	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EJF16_40023	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EJF16_40038	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_40045	ENOG4107EFR	Flavocytochrome c
EJF16_40047	ENOG4105C0D	helicase
EJF16_40058	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EJF16_40067	ENOG4107QI1	Mate efflux family protein
EJF16_40077	ENOG4108Z6B	deaminase
EJF16_40084	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EJF16_40093	ENOG4105D98	threonine synthase
EJF16_40101	ENOG4105DFM	M18 family aminopeptidase
EJF16_40103	ENOG4107QNK	)-transporter
EJF16_40109	ENOG4105CSP	Major Facilitator Superfamily
EJF16_40118	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EJF16_40130	ENOG4105D9P	serine threonine protein kinase
EJF16_40141	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EJF16_40166	ENOG4105DGW	oligopeptidase A
EJF16_40172	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_40174	ENOG4105VFU	Rna-binding protein
EJF16_40184	ENOG4105C3J	Cysteine desulfurase
EJF16_40186	ENOG4105CHR	reductase
EJF16_40202	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_40204	ENOG4105C85	amino acid
EJF16_40206	ENOG4105VG0	50S ribosomal protein l34
EJF16_40208	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EJF16_40212	ENOG4105CJQ	hydrolase, family 31
EJF16_40214	ENOG4105BZU	Histidine kinase
EJF16_40216	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EJF16_40218	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EJF16_40228	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_40230	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_40233	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EJF16_40237	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EJF16_40243	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EJF16_40259	ENOG4105D1H	recombination factor protein RarA
EJF16_40262	ENOG4105CG3	alpha amylase, catalytic region
EJF16_40267	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EJF16_40274	ENOG4107XM9	(LipO)protein
EJF16_40281	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EJF16_40289	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EJF16_40291	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EJF16_40298	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EJF16_40316	ENOG4105C9Q	fumarate hydratase class II
EJF16_40318	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EJF16_40327	ENOG4105D06	uba thif-type nad fad binding protein
EJF16_40331	ENOG4107YU2	histidine triad (hIT) protein
EJF16_40332	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_40333	ENOG4105IDI	abc transporter atp-binding protein
EJF16_40338	ENOG4105D06	uba thif-type nad fad binding protein
EJF16_40339	ENOG4105CKK	Glycosyl transferase, family 2
EJF16_40371	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EJF16_40390	ENOG4105CV8	reductase
EJF16_40393	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_40404	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EJF16_40406	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_40418	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EJF16_40424	ENOG4105C75	arginyL-tRNA synthetase
EJF16_40427	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EJF16_40428	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EJF16_40457	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EJF16_40458	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EJF16_40459	ENOG4105C54	Major Facilitator superfamily
EJF16_40472	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EJF16_40474	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EJF16_40475	ENOG4105CQB	FAD linked oxidase domain protein
EJF16_40478	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EJF16_40479	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EJF16_40480	ENOG4105CRK	lysyL-tRNA synthetase
EJF16_40483	ENOG4105CP7	Triose-phosphate isomerase
EJF16_40494	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
EJF16_40497	ENOG4105BZA	Phosphoglycerate kinase
EJF16_40503	ENOG4105K4T	epimerase
EJF16_40506	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EJF16_40507	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_40515	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_40520	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EJF16_40524	ENOG4107QSE	Dipeptidase
EJF16_40530	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
EJF16_40535	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EJF16_40542	ENOG4108V06	Glutathione peroxidase
EJF16_40548	ENOG4105CHR	reductase
EJF16_40556	ENOG4107YZX	Universal stress protein
EJF16_40558	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EJF16_40563	ENOG4105DFH	Transport of potassium into the cell (By similarity)
EJF16_40564	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EJF16_40567	ENOG4105D3R	alkyl hydroperoxide reductase
EJF16_40570	ENOG4105CHF	Glutathione S-transferase
EJF16_40578	ENOG4105C31	Tryptophanyl-tRNA synthetase
EJF16_40583	ENOG4105C3M	thioredoxin reductase
EJF16_40588	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_40589	ENOG4105HFZ	Membrane
EJF16_40598	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EJF16_40603	ENOG4105DQ4	alcohol dehydrogenase
EJF16_40617	ENOG4108JJ7	ABC transporter
EJF16_40618	ENOG4107RA9	decarboxylase
EJF16_40621	ENOG4105C2W	permease
EJF16_40627	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EJF16_40628	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EJF16_40632	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EJF16_40633	ENOG4105EE0	oxidoreductase
EJF16_40636	ENOG4107QNK	)-transporter
EJF16_40643	ENOG4108SPH	protein kinase (EC 2.7.11.1)
EJF16_40656	ENOG4108JQ1	Dehydrogenase
EJF16_40662	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EJF16_40664	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EJF16_40669	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
EJF16_40687	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_40694	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
EJF16_40699	ENOG4105D9P	serine threonine protein kinase
EJF16_40701	ENOG4105D9P	serine threonine protein kinase
EJF16_40702	ENOG4108UGD	Serine Threonine protein kinase
EJF16_40708	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
EJF16_40713	ENOG4105BZU	Histidine kinase
EJF16_40715	ENOG4105C26	Dehydrogenase
EJF16_40719	ENOG4107QPV	Serine Threonine protein kinase
EJF16_40722	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
EJF16_40727	ENOG4105C1J	atp-dependent rna helicase
EJF16_40729	ENOG4105D2S	major facilitator superfamily
EJF16_40732	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EJF16_40733	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_40738	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EJF16_40739	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EJF16_40742	ENOG4108IQI	permease
EJF16_40743	ENOG4108IQI	permease
EJF16_40746	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EJF16_40751	ENOG4105VJV	50s ribosomal protein L35
EJF16_40758	ENOG4105CSP	Major Facilitator Superfamily
EJF16_40765	ENOG4107QNK	)-transporter
EJF16_40770	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EJF16_40776	ENOG4105CPQ	Dehydrogenase
EJF16_40781	ENOG4105C2C	drug resistance transporter, Bcr CflA
EJF16_40785	ENOG4108IQI	permease
EJF16_40787	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EJF16_40788	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EJF16_40789	ENOG4105D17	glycoside hydrolase, family 3 domain protein
EJF16_40794	ENOG4107QUV	Domain protein
EJF16_40796	ENOG4105CKU	formyltetrahydrofolate synthetase
EJF16_40800	ENOG4105D9P	serine threonine protein kinase
EJF16_40801	ENOG4105CHM	Aminotransferase
EJF16_40807	ENOG4105E33	succinate dehydrogenase
EJF16_40809	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EJF16_40815	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_40823	ENOG4105BZU	Histidine kinase
EJF16_40831	ENOG4105C26	Dehydrogenase
EJF16_50011	ENOG4105M2J	Glutaredoxin
EJF16_50015	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EJF16_50025	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
EJF16_50027	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EJF16_50028	ENOG4105DJ0	Poly(A) Polymerase
EJF16_50043	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EJF16_50052	ENOG4105C85	amino acid
EJF16_50063	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EJF16_50093	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
EJF16_50098	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EJF16_50099	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EJF16_50113	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EJF16_50114	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EJF16_50118	ENOG4108DT4	serine threonine protein kinase
EJF16_50127	ENOG4105C2X	Arabinose 5-phosphate isomerase
EJF16_50129	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EJF16_50130	ENOG4108UJD	30S ribosomal protein S9
EJF16_50136	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EJF16_50138	ENOG4108RVA	ribokinase
EJF16_50147	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EJF16_50162	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
EJF16_50183	ENOG4105CQ7	ATP-dependent helicase
EJF16_50184	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EJF16_50185	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EJF16_50195	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EJF16_50196	ENOG4107TH8	cina domain protein
EJF16_50200	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJF16_50203	ENOG4105D9P	serine threonine protein kinase
EJF16_50208	ENOG4108PPE	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EJF16_50215	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EJF16_50221	ENOG4105C0D	helicase
EJF16_50223	ENOG4105C26	Dehydrogenase
EJF16_50229	ENOG4105CX6	glutaminyL-tRNA synthetase
EJF16_50233	ENOG4107Z1W	Fructose transport system kinase
EJF16_50234	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EJF16_50239	ENOG4105CV8	reductase
EJF16_50241	ENOG4105VFU	Rna-binding protein
EJF16_50244	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EJF16_50245	ENOG4105CYM	Glutathione S-transferase
EJF16_50248	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EJF16_50274	ENOG4105C7B	Threonine dehydratase
EJF16_50275	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EJF16_50276	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EJF16_50279	ENOG4105CY0	Metallo-Beta-Lactamase
EJF16_50280	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
EJF16_50285	ENOG4105C1J	atp-dependent rna helicase
EJF16_50291	ENOG4105C26	Dehydrogenase
EJF16_50296	ENOG4105EAC	phosphoserine phosphatase
EJF16_50301	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_50307	ENOG4105EV9	Alpha Beta Hydrolase
EJF16_50315	ENOG4105C26	Dehydrogenase
EJF16_50319	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EJF16_50327	ENOG4105C2X	Arabinose 5-phosphate isomerase
EJF16_50329	ENOG4108IQI	permease
EJF16_50333	ENOG4105CFH	Aspartokinase
EJF16_50347	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EJF16_50353	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EJF16_50355	ENOG4105DJ4	phosphatidylserine decarboxylase
EJF16_50374	ENOG4105C22	threonyL-tRNA synthetase
EJF16_50385	ENOG4105C0D	helicase
EJF16_50387	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EJF16_50389	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
EJF16_50393	ENOG4105MA4	psp1 domain protein
EJF16_50395	ENOG4105D9P	serine threonine protein kinase
EJF16_50396	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
EJF16_50402	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EJF16_50404	ENOG4105CX6	glutaminyL-tRNA synthetase
EJF16_50414	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EJF16_50437	ENOG4105BZ1	(ABC) transporter
EJF16_50440	ENOG4105D1F	ATP-binding protein
EJF16_50441	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EJF16_50443	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EJF16_50444	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EJF16_50445	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EJF16_50452	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EJF16_50462	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EJF16_50465	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EJF16_50466	ENOG4105CDH	Citrulline--aspartate ligase
EJF16_50474	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EJF16_50476	ENOG4105E53	ec 3.2.1.28
EJF16_50478	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EJF16_50479	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EJF16_50495	ENOG4105CGF	Aromatic amino acid aminotransferase
EJF16_50498	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EJF16_50505	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EJF16_50507	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EJF16_50508	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EJF16_50509	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
EJF16_50527	ENOG4107R37	Glutamate dehydrogenase
EJF16_50529	ENOG4105CKI	cobalamin synthesis protein
EJF16_50539	ENOG4105D9P	serine threonine protein kinase
EJF16_50543	ENOG41086MH	50S ribosomal protein L36
EJF16_50550	ENOG4105C1J	atp-dependent rna helicase
EJF16_50558	ENOG4105K5M	30s ribosomal protein S16
EJF16_50566	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
EJF16_50571	ENOG4105C1J	atp-dependent rna helicase
EJF16_50572	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EJF16_50578	ENOG4105CEP	NADH dehydrogenase
EJF16_50592	ENOG4107RIQ	Sulfate adenylate transferase
EJF16_50610	ENOG4105K63	Thioredoxin
EJF16_50616	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EJF16_50618	ENOG4105C0D	helicase
EJF16_50619	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EJF16_50620	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EJF16_50633	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_50649	ENOG4105EIP	mannose-6-phosphate isomerase
EJF16_50651	ENOG4105D1F	ATP-binding protein
EJF16_50665	ENOG4105CAQ	asparagine synthetase
EJF16_50685	ENOG4105TPV	
EJF16_50697	ENOG4108IQI	permease
EJF16_50708	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EJF16_50709	ENOG4105D9P	serine threonine protein kinase
EJF16_50712	ENOG4108I5C	dEAD DEAH box helicase
EJF16_50716	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_50718	ENOG4108IQI	permease
EJF16_50719	ENOG4108IQI	permease
EJF16_50732	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EJF16_50735	ENOG4107XDR	Lactoylglutathione lyase
EJF16_50736	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EJF16_50737	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EJF16_60003	ENOG4107QNK	)-transporter
EJF16_60004	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
EJF16_60005	ENOG4105CMR	udp-glucose 4-epimerase
EJF16_60008	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
EJF16_60010	ENOG4105CFM	UPF0317 protein
EJF16_60017	ENOG4105D9P	serine threonine protein kinase
EJF16_60018	ENOG4105CD8	aminopeptidase N
EJF16_60022	ENOG4105HS1	biotin--protein ligase
EJF16_60024	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EJF16_60026	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EJF16_60029	ENOG4105C5H	ABC transporter
EJF16_60049	ENOG4105C8N	cysteinyl-tRNA synthetase
EJF16_60083	ENOG4105D9P	serine threonine protein kinase
EJF16_60093	ENOG4108ZX6	Electron transport protein SCO1 SenC
EJF16_60101	ENOG4105C5H	ABC transporter
EJF16_60115	ENOG4105BZ1	(ABC) transporter
EJF16_60116	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
EJF16_60122	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EJF16_60129	ENOG4105D1H	recombination factor protein RarA
EJF16_60130	ENOG4105DQ4	alcohol dehydrogenase
EJF16_60138	ENOG4108R6K	riboflavin synthase, subunit alpha
EJF16_60140	ENOG4105CQ7	ATP-dependent helicase
EJF16_60146	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EJF16_60156	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EJF16_60159	ENOG4105C54	Major Facilitator superfamily
EJF16_60175	ENOG41068W2	Cytochrome p-450
EJF16_60176	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
EJF16_60181	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EJF16_60197	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EJF16_60211	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EJF16_60212	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
EJF16_60240	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EJF16_60252	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EJF16_60263	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_60268	ENOG4108M9J	MaoC like domain protein
EJF16_60283	ENOG4105C1J	atp-dependent rna helicase
EJF16_60284	ENOG4105C85	amino acid
EJF16_60287	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EJF16_60305	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EJF16_60308	ENOG4105D9P	serine threonine protein kinase
EJF16_60317	ENOG4105DQ4	alcohol dehydrogenase
EJF16_60324	ENOG4108JZA	Homocitrate synthase
EJF16_60326	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EJF16_60328	ENOG4105D9P	serine threonine protein kinase
EJF16_60331	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EJF16_60334	ENOG4105CHU	acetyl-coa acetyltransferase
EJF16_60336	ENOG4105D9P	serine threonine protein kinase
EJF16_60339	ENOG4105D9P	serine threonine protein kinase
EJF16_60341	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EJF16_60345	ENOG4105SYT	Methylenetetrahydrofolate reductase
EJF16_60348	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EJF16_60350	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EJF16_60360	ENOG4105D9P	serine threonine protein kinase
EJF16_60361	ENOG4105C8Y	Acetylornithine aminotransferase
EJF16_60365	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EJF16_60372	ENOG4108V06	Glutathione peroxidase
EJF16_60375	ENOG4108IQI	permease
EJF16_60380	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
EJF16_60381	ENOG4105EM7	Selenocysteine-specific translation elongation factor
EJF16_60386	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EJF16_60388	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_60396	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EJF16_60412	ENOG4105CQ7	ATP-dependent helicase
EJF16_60413	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EJF16_60416	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EJF16_60436	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
EJF16_60437	ENOG4105C8V	SAICAR synthetase
EJF16_60444	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EJF16_60446	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EJF16_60448	ENOG4105HS1	biotin--protein ligase
EJF16_60452	ENOG4105CD8	aminopeptidase N
EJF16_60453	ENOG4105D9P	serine threonine protein kinase
EJF16_70006	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EJF16_70014	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
EJF16_70029	ENOG4105C3F	Signal peptidase i
EJF16_70042	ENOG4105D9P	serine threonine protein kinase
EJF16_70048	ENOG4105EUB	pirin domain protein
EJF16_70055	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EJF16_70070	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EJF16_70071	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_70072	ENOG4105C5R	Aminotransferase
EJF16_70081	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EJF16_70082	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
EJF16_70088	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EJF16_70093	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
EJF16_70094	ENOG4105CQ2	DNA polymerase
EJF16_70097	ENOG4105CMQ	Chloride channel
EJF16_70105	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EJF16_70113	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EJF16_70117	ENOG4105C6K	Malic enzyme
EJF16_70118	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
EJF16_70133	ENOG4105CSH	Transporter
EJF16_70146	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EJF16_70156	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EJF16_70163	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EJF16_70168	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EJF16_70169	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJF16_70173	ENOG4108Z6B	deaminase
EJF16_70179	ENOG4105CE9	30S ribosomal protein S2
EJF16_70203	ENOG4107QNK	)-transporter
EJF16_70244	ENOG4105C3G	gtp-binding protein
EJF16_70251	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EJF16_70260	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EJF16_70265	ENOG4105D9P	serine threonine protein kinase
EJF16_70268	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EJF16_70272	ENOG4105C59	p-type ATPase
EJF16_70278	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EJF16_70279	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EJF16_70288	ENOG4105CMQ	Chloride channel
EJF16_70298	ENOG4105DBV	ornithine carbamoyltransferase
EJF16_70304	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EJF16_70310	ENOG4105D9P	serine threonine protein kinase
EJF16_70315	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EJF16_70318	ENOG4105G6Z	alkaline phosphatase
EJF16_70319	ENOG4105C2C	drug resistance transporter, Bcr CflA
EJF16_70332	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EJF16_70333	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EJF16_70344	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EJF16_70346	ENOG4108YZ4	nudix hydrolase
EJF16_70349	ENOG4105C54	Major Facilitator superfamily
EJF16_70363	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EJF16_80007	ENOG4105EAH	synthase
EJF16_80016	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EJF16_80025	ENOG4105E2B	Taurine dioxygenase
EJF16_80028	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EJF16_80035	ENOG4105C59	p-type ATPase
EJF16_80048	ENOG4105CVK	Glutamate decarboxylase
EJF16_80055	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EJF16_80059	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EJF16_80063	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EJF16_80076	ENOG4105D9P	serine threonine protein kinase
EJF16_80088	ENOG4105CFG	Acts as a chaperone (By similarity)
EJF16_80089	ENOG410870F	Cyclic nucleotide-binding protein
EJF16_80092	ENOG4105BZU	Histidine kinase
EJF16_80094	ENOG4105C5H	ABC transporter
EJF16_80113	ENOG4105CZQ	inner membrane transport protein YdhC
EJF16_80116	ENOG4108V5V	Serine Threonine protein kinase
EJF16_80118	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
EJF16_80121	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EJF16_80122	ENOG4108QVN	serine threonine protein kinase
EJF16_80124	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EJF16_80127	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EJF16_80128	ENOG4105EW6	flavin reductase domain protein, FMN-binding
EJF16_80129	ENOG4105CQB	FAD linked oxidase domain protein
EJF16_80131	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EJF16_80132	ENOG4105C22	threonyL-tRNA synthetase
EJF16_80139	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EJF16_80140	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EJF16_80145	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
EJF16_80154	ENOG4108IEH	NADH dehydrogenase subunit g
EJF16_80172	ENOG4105CH6	catalase
EJF16_80177	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EJF16_80193	ENOG4105D9P	serine threonine protein kinase
EJF16_80213	ENOG4107TPY	serine threonine protein kinase
EJF16_80219	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EJF16_80228	ENOG4108IQI	permease
EJF16_80233	ENOG4105IDI	abc transporter atp-binding protein
EJF16_80236	ENOG4105D9P	serine threonine protein kinase
EJF16_80244	ENOG4105C10	Electron transfer flavoprotein
EJF16_80250	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
EJF16_80254	ENOG4108MGY	Histidine kinase
EJF16_80256	ENOG4105DKW	ABC transporter
EJF16_80257	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EJF16_80261	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
EJF16_80262	ENOG4105CHW	UPF0052 protein
EJF16_80265	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EJF16_80270	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EJF16_80289	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EJF16_80292	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EJF16_80300	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
EJF16_80308	ENOG4105C37	(CBS) domain
EJF16_80313	ENOG4105CN2	monooxygenase, FAD-binding
EJF16_80316	ENOG4105MSY	salicylate hydroxylase