locus-tag	class	description
EJF16_10004	COG5277	cytoskeleton organization
EJF16_10006	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EJF16_10016	COG0515	serine threonine protein kinase
EJF16_10016	COG2815	serine threonine protein kinase
EJF16_10019	COG2271	Major facilitator Superfamily
EJF16_10022	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJF16_10027	COG0833	amino acid
EJF16_10031	COG3579	cysteine-type endopeptidase activity
EJF16_10051	COG2815	serine threonine protein kinase
EJF16_10051	COG0515	serine threonine protein kinase
EJF16_10053	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJF16_10060	COG0489	protein tyrosine kinase activity
EJF16_10100	COG0515	serine threonine protein kinase
EJF16_10109	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EJF16_10118	COG0681	Belongs to the peptidase S26 family
EJF16_10125	COG2132	Multicopper oxidase
EJF16_10132	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJF16_10135	COG1132	(ABC) transporter
EJF16_10148	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJF16_10158	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJF16_10159	COG2319	Wd-40 repeat
EJF16_10166	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_10168	COG0469	pyruvate kinase activity
EJF16_10177	COG0833	amino acid
EJF16_10182	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJF16_10185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EJF16_10188	COG2814	Major facilitator Superfamily
EJF16_10190	COG1501	Belongs to the glycosyl hydrolase 31 family
EJF16_10196	COG2895	sulfate adenylyltransferase (ATP) activity
EJF16_10196	COG0529	Catalyzes the synthesis of activated sulfate
EJF16_10200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EJF16_10201	COG0515	serine threonine protein kinase
EJF16_10218	COG0514	ATP-dependent DNA helicase (RecQ)
EJF16_10233	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJF16_10236	COG0110	maltose O-acetyltransferase activity
EJF16_10237	COG0656	L-ascorbic acid biosynthetic process
EJF16_10244	COG0724	RNA recognition motif
EJF16_10246	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EJF16_10247	COG0484	heat shock protein binding
EJF16_10254	COG0277	FAD linked oxidase domain protein
EJF16_10255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJF16_10273	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EJF16_10279	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_10286	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJF16_10290	COG2873	o-acetylhomoserine
EJF16_10294	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EJF16_10304	COG0442	prolyl-tRNA aminoacylation
EJF16_10307	COG0484	heat shock protein binding
EJF16_10322	COG2814	Major facilitator Superfamily
EJF16_10324	COG0456	acetyltransferase
EJF16_10325	COG0406	alpha-ribazole phosphatase activity
EJF16_10341	COG0534	Mate efflux family protein
EJF16_10348	COG1643	Atp-dependent helicase
EJF16_10352	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_10357	COG0306	phosphate transporter
EJF16_10368	COG0833	amino acid
EJF16_10383	COG0288	reversible hydration of carbon dioxide
EJF16_10385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_10390	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_10416	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EJF16_10422	COG2271	Major facilitator Superfamily
EJF16_10424	COG2814	Major facilitator Superfamily
EJF16_10427	COG2814	Major facilitator Superfamily
EJF16_10428	COG2814	Major facilitator Superfamily
EJF16_10429	COG1448	Aminotransferase
EJF16_10430	COG0033	Phosphoglucomutase
EJF16_10434	COG0564	pseudouridine synthase activity
EJF16_10435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EJF16_10438	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJF16_10444	COG0659	secondary active sulfate transmembrane transporter activity
EJF16_10453	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EJF16_10460	COG0833	amino acid
EJF16_10483	COG0529	Catalyzes the synthesis of activated sulfate
EJF16_10483	COG2895	sulfate adenylyltransferase (ATP) activity
EJF16_10485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EJF16_10486	COG0656	L-ascorbic acid biosynthetic process
EJF16_10500	COG1053	succinate dehydrogenase
EJF16_10502	COG1394	ATPase activity, coupled to movement of substances
EJF16_10514	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJF16_10516	COG2271	Major facilitator Superfamily
EJF16_10521	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EJF16_10524	COG0656	L-ascorbic acid biosynthetic process
EJF16_10526	COG0107	imidazoleglycerol-phosphate synthase activity
EJF16_10538	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EJF16_10550	COG0656	L-ascorbic acid biosynthetic process
EJF16_10563	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJF16_10584	COG0515	serine threonine protein kinase
EJF16_10586	COG2815	serine threonine protein kinase
EJF16_10586	COG0515	serine threonine protein kinase
EJF16_10609	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EJF16_10611	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJF16_10618	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJF16_10620	COG0542	response to heat
EJF16_10628	COG0459	protein refolding
EJF16_10639	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EJF16_10651	COG0049	tRNA binding
EJF16_10669	COG1584	GPR1 FUN34 yaaH family protein
EJF16_10672	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJF16_10675	COG0539	negative regulation of cytoplasmic translation
EJF16_10690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EJF16_10692	COG0833	amino acid
EJF16_10730	COG4178	(ABC) transporter
EJF16_10731	COG0193	aminoacyl-tRNA hydrolase activity
EJF16_10738	COG1643	Atp-dependent helicase
EJF16_10746	COG0081	regulation of translation
EJF16_10747	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJF16_10747	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJF16_10766	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_10780	COG0833	amino acid
EJF16_10781	COG0833	amino acid
EJF16_10783	COG0235	Class ii aldolase
EJF16_10794	COG0612	Peptidase, M16
EJF16_10800	COG0484	heat shock protein binding
EJF16_10804	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJF16_10806	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EJF16_10807	COG0626	cystathionine gamma-synthase activity
EJF16_10810	COG0006	proline dipeptidase activity
EJF16_10827	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJF16_10827	COG2124	cytochrome p450
EJF16_10834	COG2814	Major facilitator Superfamily
EJF16_10845	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EJF16_10849	COG4702	Belongs to the UPF0303 family
EJF16_10855	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EJF16_10877	COG0515	serine threonine protein kinase
EJF16_10881	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EJF16_10891	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EJF16_10891	COG0644	oxidoreductase
EJF16_10901	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EJF16_10907	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_10912	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EJF16_10915	COG2814	Major facilitator Superfamily
EJF16_10918	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJF16_10922	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EJF16_10931	COG0515	serine threonine protein kinase
EJF16_10931	COG3266	domain, Protein
EJF16_10952	COG0017	Asparaginyl-tRNA synthetase
EJF16_10953	COG0459	protein refolding
EJF16_10955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EJF16_10980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJF16_10985	COG0545	Peptidyl-prolyl cis-trans isomerase
EJF16_10995	COG0019	diaminopimelate decarboxylase activity
EJF16_10999	COG0534	Mate efflux family protein
EJF16_11002	COG0656	L-ascorbic acid biosynthetic process
EJF16_11010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EJF16_11012	COG3961	Belongs to the TPP enzyme family
EJF16_11018	COG0515	serine threonine protein kinase
EJF16_11024	COG0326	Molecular chaperone. Has ATPase activity
EJF16_11028	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EJF16_11029	COG1132	(ABC) transporter
EJF16_11033	COG0156	8-amino-7-oxononanoate synthase activity
EJF16_11042	COG1304	FMN binding
EJF16_11048	COG0477	Major facilitator Superfamily
EJF16_11048	COG2814	Major facilitator Superfamily
EJF16_11058	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EJF16_11062	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EJF16_11066	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJF16_11076	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EJF16_11079	COG0556	nucleotide-excision repair
EJF16_11082	COG1793	dna ligase
EJF16_11085	COG3961	Belongs to the TPP enzyme family
EJF16_11090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EJF16_11097	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_11103	COG0515	serine threonine protein kinase
EJF16_11104	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJF16_11110	COG3976	FMN-binding domain protein
EJF16_11110	COG1053	succinate dehydrogenase
EJF16_11113	COG3579	cysteine-type endopeptidase activity
EJF16_11118	COG0217	transcriptional regulatory protein
EJF16_11120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJF16_11125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EJF16_11127	COG0531	amino acid
EJF16_11141	COG0009	L-threonylcarbamoyladenylate synthase
EJF16_11155	COG0515	serine threonine protein kinase
EJF16_11157	COG2040	homocysteine
EJF16_11159	COG1131	(ABC) transporter
EJF16_11161	COG0105	UTP biosynthetic process
EJF16_11165	COG0656	L-ascorbic acid biosynthetic process
EJF16_11173	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EJF16_11197	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EJF16_11206	COG2814	Major facilitator Superfamily
EJF16_11207	COG2814	Major facilitator Superfamily
EJF16_11220	COG0006	proline dipeptidase activity
EJF16_20003	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_20012	COG0596	Alpha beta hydrolase
EJF16_20013	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EJF16_20018	COG0308	aminopeptidase N
EJF16_20020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJF16_20021	COG0563	adenylate kinase activity
EJF16_20027	COG1121	(ABC) transporter
EJF16_20039	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EJF16_20044	COG2815	serine threonine protein kinase
EJF16_20044	COG0515	serine threonine protein kinase
EJF16_20058	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EJF16_20061	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJF16_20065	COG0477	Major facilitator Superfamily
EJF16_20066	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EJF16_20068	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EJF16_20073	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJF16_20084	COG1024	Enoyl-CoA hydratase
EJF16_20085	COG0513	Belongs to the DEAD box helicase family
EJF16_20091	COG2815	serine threonine protein kinase
EJF16_20091	COG0515	serine threonine protein kinase
EJF16_20095	COG2226	methyltransferase
EJF16_20120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJF16_20124	COG0076	glutamate decarboxylase activity
EJF16_20135	COG0123	including yeast histone deacetylase and acetoin utilization protein
EJF16_20138	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_20140	COG1793	dna ligase
EJF16_20154	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJF16_20155	COG0596	Alpha beta hydrolase
EJF16_20161	COG0400	carboxylic ester hydrolase activity
EJF16_20162	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJF16_20169	COG0133	tryptophan synthase activity
EJF16_20173	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJF16_20177	COG0515	serine threonine protein kinase
EJF16_20177	COG2815	serine threonine protein kinase
EJF16_20179	COG1058	Belongs to the CinA family
EJF16_20179	COG1546	Belongs to the CinA family
EJF16_20183	COG0443	Heat shock 70 kDa protein
EJF16_20191	COG0588	phosphoglycerate mutase activity
EJF16_20196	COG0515	serine threonine protein kinase
EJF16_20215	COG0251	oxidation-reduction process
EJF16_20240	COG0649	NAD binding
EJF16_20241	COG0484	heat shock protein binding
EJF16_20259	COG0450	alkyl hydroperoxide reductase
EJF16_20263	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJF16_20264	COG0515	serine threonine protein kinase
EJF16_20264	COG2815	serine threonine protein kinase
EJF16_20272	COG1448	Aminotransferase
EJF16_20274	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EJF16_20277	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EJF16_20281	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJF16_20287	COG0542	response to heat
EJF16_20291	COG2814	Major facilitator Superfamily
EJF16_20291	COG0477	Major facilitator Superfamily
EJF16_20297	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EJF16_20303	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_20307	COG0523	cobalamin synthesis protein
EJF16_20311	COG0477	Major facilitator Superfamily
EJF16_20326	COG3118	belongs to the thioredoxin family
EJF16_20341	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EJF16_20345	COG0457	Tetratricopeptide repeat
EJF16_20345	COG0515	serine threonine protein kinase
EJF16_20347	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJF16_20352	COG2132	Multicopper oxidase
EJF16_20371	COG0025	NhaP-type Na H and K H
EJF16_20377	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJF16_20377	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJF16_20386	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EJF16_20387	COG0460	homoserine dehydrogenase
EJF16_20387	COG0527	aspartate kinase activity
EJF16_20392	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJF16_20393	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJF16_20414	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EJF16_20432	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EJF16_20440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EJF16_20441	COG0513	Belongs to the DEAD box helicase family
EJF16_20447	COG0165	Argininosuccinate lyase
EJF16_20448	COG0017	Asparaginyl-tRNA synthetase
EJF16_20449	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJF16_20451	COG0017	Asparaginyl-tRNA synthetase
EJF16_20456	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EJF16_20458	COG1113	amino acid transport
EJF16_20459	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EJF16_20467	COG0538	isocitrate dehydrogenase activity
EJF16_20469	COG0463	Glycosyl transferase, family 2
EJF16_20470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJF16_20472	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EJF16_20486	COG1162	GTPase activity
EJF16_20495	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_20500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EJF16_20500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EJF16_20506	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EJF16_20518	COG0482	sulfurtransferase activity
EJF16_20534	COG0484	heat shock protein binding
EJF16_20539	COG0123	including yeast histone deacetylase and acetoin utilization protein
EJF16_20540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EJF16_20552	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EJF16_20554	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EJF16_20578	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_20579	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJF16_20582	COG0552	protein localization to endoplasmic reticulum
EJF16_20583	COG0688	phosphatidylethanolamine metabolic process
EJF16_20585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJF16_20585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJF16_20586	COG0154	amidase activity
EJF16_20587	COG0302	gtp cyclohydrolase
EJF16_20588	COG0557	exoribonuclease II activity
EJF16_20597	COG0205	6-phosphofructokinase activity
EJF16_20605	COG1012	belongs to the aldehyde dehydrogenase family
EJF16_20607	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJF16_20609	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EJF16_20622	COG0515	serine threonine protein kinase
EJF16_20626	COG0459	protein refolding
EJF16_20629	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJF16_20632	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EJF16_20661	COG1404	Belongs to the peptidase S8 family
EJF16_20662	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EJF16_20668	COG0666	response to abiotic stimulus
EJF16_20670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJF16_20674	COG0515	serine threonine protein kinase
EJF16_20679	COG0113	porphobilinogen synthase activity
EJF16_20682	COG0588	phosphoglycerate mutase activity
EJF16_20685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJF16_20687	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EJF16_20688	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EJF16_20690	COG0833	amino acid
EJF16_20698	COG0504	CTP synthase activity
EJF16_20701	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EJF16_20706	COG0154	amidase activity
EJF16_20707	COG2271	Major facilitator Superfamily
EJF16_20724	COG1362	aminopeptidase activity
EJF16_20745	COG0459	protein refolding
EJF16_20747	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJF16_20755	COG2814	Major facilitator Superfamily
EJF16_20760	COG0210	DNA helicase
EJF16_20764	COG0440	acetolactate synthase activity
EJF16_20773	COG1069	ribulokinase activity
EJF16_20789	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EJF16_20795	COG1132	(ABC) transporter
EJF16_20800	COG0457	Tetratricopeptide repeat
EJF16_20800	COG1477	protein flavinylation
EJF16_20803	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_20814	COG0833	amino acid
EJF16_20823	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EJF16_20831	COG0024	Methionine aminopeptidase
EJF16_20839	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EJF16_20843	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_20844	COG1584	GPR1 FUN34 yaaH family protein
EJF16_20846	COG4221	oxidoreductase activity
EJF16_20847	COG0515	serine threonine protein kinase
EJF16_20850	COG0525	valine-tRNA ligase activity
EJF16_20858	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EJF16_20878	COG0488	(ABC) transporter
EJF16_20883	COG1012	belongs to the aldehyde dehydrogenase family
EJF16_20888	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EJF16_20891	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJF16_20896	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EJF16_20900	COG4221	oxidoreductase activity
EJF16_20904	COG0505	Belongs to the CarA family
EJF16_20916	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EJF16_20918	COG0191	fructose-bisphosphate aldolase activity
EJF16_20924	COG2226	methyltransferase
EJF16_20930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EJF16_20931	COG0515	serine threonine protein kinase
EJF16_20935	COG0183	Belongs to the thiolase family
EJF16_20940	COG0515	serine threonine protein kinase
EJF16_20948	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_20949	COG2814	Major facilitator Superfamily
EJF16_20962	COG0513	Belongs to the DEAD box helicase family
EJF16_20968	COG2814	Major facilitator Superfamily
EJF16_30002	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJF16_30010	COG0405	Gamma-glutamyltransferase
EJF16_30015	COG0833	amino acid
EJF16_30021	COG0481	GTPase activity
EJF16_30038	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJF16_30045	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EJF16_30051	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EJF16_30052	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EJF16_30053	COG0571	ribonuclease III activity
EJF16_30067	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_30075	COG1024	Enoyl-CoA hydratase
EJF16_30076	COG5277	cytoskeleton organization
EJF16_30078	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJF16_30083	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EJF16_30084	COG1819	glycosyl
EJF16_30085	COG1132	(ABC) transporter
EJF16_30092	COG0484	heat shock protein binding
EJF16_30093	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_30101	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_30103	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EJF16_30117	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EJF16_30119	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EJF16_30122	COG0154	amidase activity
EJF16_30126	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EJF16_30138	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
EJF16_30145	COG3118	belongs to the thioredoxin family
EJF16_30147	COG0756	dUTP diphosphatase activity
EJF16_30151	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EJF16_30164	COG1132	(ABC) transporter
EJF16_30165	COG0085	RNA polymerase activity
EJF16_30184	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EJF16_30190	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EJF16_30194	COG1196	nuclear chromosome segregation
EJF16_30210	COG0484	heat shock protein binding
EJF16_30214	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJF16_30215	COG0678	peroxiredoxin activity
EJF16_30219	COG1132	(ABC) transporter
EJF16_30230	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_30236	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EJF16_30239	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
EJF16_30262	COG0513	Belongs to the DEAD box helicase family
EJF16_30268	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EJF16_30276	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EJF16_30281	COG0024	Methionine aminopeptidase
EJF16_30288	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_30290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJF16_30293	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJF16_30295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EJF16_30310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJF16_30315	COG4581	dead DEAH box helicase
EJF16_30326	COG3474	cytochrome
EJF16_30330	COG1132	(ABC) transporter
EJF16_30348	COG0585	pseudouridine synthase activity
EJF16_30351	COG2815	serine threonine protein kinase
EJF16_30351	COG0515	serine threonine protein kinase
EJF16_30353	COG2814	Major facilitator Superfamily
EJF16_30358	COG4948	Mandelate Racemase Muconate Lactonizing
EJF16_30359	COG3104	oligopeptide transport
EJF16_30365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EJF16_30370	COG0363	glucosamine-6-phosphate deaminase activity
EJF16_30371	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EJF16_30373	COG0484	heat shock protein binding
EJF16_30393	COG0484	heat shock protein binding
EJF16_30399	COG0109	protoheme IX farnesyltransferase activity
EJF16_30400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EJF16_30407	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJF16_30408	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJF16_30410	COG0424	maF-like protein
EJF16_30419	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJF16_30420	COG1914	H( )-stimulated, divalent metal cation uptake system
EJF16_30431	COG0406	alpha-ribazole phosphatase activity
EJF16_30435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_30437	COG4581	dead DEAH box helicase
EJF16_30441	COG0494	nUDIX hydrolase
EJF16_30444	COG0443	Heat shock 70 kDa protein
EJF16_30447	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EJF16_30461	COG1643	Atp-dependent helicase
EJF16_30464	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EJF16_30476	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EJF16_30477	COG0626	cystathionine gamma-synthase activity
EJF16_30478	COG2857	Cytochrome c1
EJF16_30478	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJF16_30499	COG0542	response to heat
EJF16_30501	COG0351	phosphomethylpyrimidine kinase
EJF16_30512	COG0012	GTP binding
EJF16_30538	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJF16_30559	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EJF16_30566	COG0175	sulfate reduction
EJF16_30569	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EJF16_30578	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EJF16_30589	COG0515	serine threonine protein kinase
EJF16_30593	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EJF16_30605	COG1362	aminopeptidase activity
EJF16_30608	COG0515	serine threonine protein kinase
EJF16_30608	COG2815	serine threonine protein kinase
EJF16_30612	COG0004	ammonium transporteR
EJF16_30613	COG0028	Belongs to the TPP enzyme family
EJF16_30615	COG1063	alcohol dehydrogenase
EJF16_30624	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EJF16_30632	COG2815	serine threonine protein kinase
EJF16_30632	COG0515	serine threonine protein kinase
EJF16_30637	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EJF16_30648	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EJF16_30661	COG0575	Belongs to the CDS family
EJF16_30672	COG0481	GTPase activity
EJF16_30695	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EJF16_30699	COG0556	nucleotide-excision repair
EJF16_30714	COG0512	Glutamine amidotransferase of anthranilate synthase
EJF16_30714	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EJF16_30724	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJF16_30729	COG0022	dehydrogenase e1 component
EJF16_30729	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJF16_30735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EJF16_30744	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EJF16_30746	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_30747	COG0484	heat shock protein binding
EJF16_30749	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJF16_30756	COG0588	phosphoglycerate mutase activity
EJF16_30763	COG0484	heat shock protein binding
EJF16_30789	COG0724	RNA recognition motif
EJF16_30797	COG0363	glucosamine-6-phosphate deaminase activity
EJF16_30806	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EJF16_30807	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EJF16_30813	COG0513	Belongs to the DEAD box helicase family
EJF16_30814	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJF16_30817	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJF16_30817	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJF16_30831	COG0662	Cupin 2, conserved barrel domain protein
EJF16_30835	COG0822	iron-sulfur transferase activity
EJF16_30846	COG0572	uridine kinase
EJF16_30847	COG0513	Belongs to the DEAD box helicase family
EJF16_30851	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJF16_30855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EJF16_30868	COG2351	hydroxyisourate hydrolase activity
EJF16_30873	COG0154	amidase activity
EJF16_30878	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJF16_30881	COG1196	nuclear chromosome segregation
EJF16_30896	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EJF16_30907	COG0564	pseudouridine synthase activity
EJF16_30926	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EJF16_30929	COG0259	pyridoxamine-phosphate oxidase activity
EJF16_30930	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJF16_30931	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJF16_30942	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_30945	COG1196	nuclear chromosome segregation
EJF16_30946	COG0006	proline dipeptidase activity
EJF16_30949	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EJF16_30951	COG0193	aminoacyl-tRNA hydrolase activity
EJF16_30968	COG0004	ammonium transporteR
EJF16_40003	COG1064	alcohol dehydrogenase
EJF16_40004	COG1064	alcohol dehydrogenase
EJF16_40017	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJF16_40023	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EJF16_40038	COG0443	Heat shock 70 kDa protein
EJF16_40045	COG1053	succinate dehydrogenase
EJF16_40047	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_40067	COG0534	Mate efflux family protein
EJF16_40077	COG0590	tRNA wobble adenosine to inosine editing
EJF16_40079	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EJF16_40084	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJF16_40101	COG1362	aminopeptidase activity
EJF16_40103	COG2814	Major facilitator Superfamily
EJF16_40109	COG2271	Major facilitator Superfamily
EJF16_40118	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EJF16_40120	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_40130	COG0515	serine threonine protein kinase
EJF16_40166	COG0339	signal peptide processing
EJF16_40172	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_40174	COG0724	RNA recognition motif
EJF16_40179	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EJF16_40184	COG1104	cysteine desulfurase activity
EJF16_40186	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_40192	COG2814	Major facilitator Superfamily
EJF16_40202	COG0484	heat shock protein binding
EJF16_40204	COG1113	amino acid transport
EJF16_40206	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EJF16_40208	COG1196	nuclear chromosome segregation
EJF16_40209	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJF16_40212	COG1501	Belongs to the glycosyl hydrolase 31 family
EJF16_40216	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJF16_40218	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EJF16_40228	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_40230	COG0484	heat shock protein binding
EJF16_40233	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJF16_40234	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EJF16_40243	COG0135	phosphoribosylanthranilate isomerase activity
EJF16_40259	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EJF16_40259	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EJF16_40267	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EJF16_40274	COG1073	alpha beta
EJF16_40281	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EJF16_40289	COG0588	phosphoglycerate mutase activity
EJF16_40291	COG0316	Belongs to the HesB IscA family
EJF16_40298	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJF16_40316	COG0114	fumarate hydratase activity
EJF16_40318	COG0352	thiamine-phosphate diphosphorylase activity
EJF16_40327	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EJF16_40331	COG0537	adenosine 5'-monophosphoramidase activity
EJF16_40332	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_40333	COG1716	ATPase activity
EJF16_40333	COG1131	(ABC) transporter
EJF16_40333	COG0842	Transport permease protein
EJF16_40338	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EJF16_40339	COG0463	Glycosyl transferase, family 2
EJF16_40353	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EJF16_40362	COG0069	glutamate synthase activity
EJF16_40362	COG0070	glutamate synthase
EJF16_40362	COG0067	glutamate synthase
EJF16_40371	COG0321	lipoyl(octanoyl) transferase activity
EJF16_40386	COG0612	Peptidase, M16
EJF16_40390	COG0656	L-ascorbic acid biosynthetic process
EJF16_40393	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_40394	COG0450	alkyl hydroperoxide reductase
EJF16_40404	COG1136	(ABC) transporter
EJF16_40406	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_40418	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EJF16_40427	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EJF16_40428	COG0085	RNA polymerase activity
EJF16_40458	COG0439	Biotin carboxylase
EJF16_40459	COG2814	Major facilitator Superfamily
EJF16_40472	COG0156	8-amino-7-oxononanoate synthase activity
EJF16_40474	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EJF16_40475	COG0277	FAD linked oxidase domain protein
EJF16_40478	COG0051	transcription antitermination factor activity, RNA binding
EJF16_40479	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EJF16_40480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EJF16_40483	COG0149	triose-phosphate isomerase activity
EJF16_40494	COG1612	heme a metabolic process
EJF16_40497	COG0126	phosphoglycerate kinase activity
EJF16_40503	COG0702	epimerase
EJF16_40506	COG0138	bifunctional purine biosynthesis protein purh
EJF16_40507	COG0484	heat shock protein binding
EJF16_40515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_40520	COG0233	cytoplasmic translational termination
EJF16_40524	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJF16_40530	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EJF16_40535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EJF16_40542	COG0386	Belongs to the glutathione peroxidase family
EJF16_40548	COG1028	Short-chain dehydrogenase reductase Sdr
EJF16_40556	COG0589	response to stress
EJF16_40558	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EJF16_40563	COG3158	transport of potassium into the cell
EJF16_40564	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EJF16_40567	COG0450	alkyl hydroperoxide reductase
EJF16_40570	COG0435	Glutathione S-transferase
EJF16_40578	COG0180	Tryptophanyl-tRNA synthetase
EJF16_40588	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_40589	COG0670	Belongs to the BI1 family
EJF16_40598	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EJF16_40603	COG1064	alcohol dehydrogenase
EJF16_40609	COG0513	Belongs to the DEAD box helicase family
EJF16_40617	COG5265	(ABC) transporter
EJF16_40618	COG3961	Belongs to the TPP enzyme family
EJF16_40621	COG2233	PERMEase
EJF16_40628	COG1196	nuclear chromosome segregation
EJF16_40632	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJF16_40632	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJF16_40633	COG0673	inositol 2-dehydrogenase activity
EJF16_40636	COG2814	Major facilitator Superfamily
EJF16_40643	COG0515	serine threonine protein kinase
EJF16_40656	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EJF16_40662	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EJF16_40664	COG2226	methyltransferase
EJF16_40669	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJF16_40687	COG0443	Heat shock 70 kDa protein
EJF16_40694	COG0432	Pfam Uncharacterised protein family UPF0047
EJF16_40699	COG2815	serine threonine protein kinase
EJF16_40699	COG0515	serine threonine protein kinase
EJF16_40701	COG2815	serine threonine protein kinase
EJF16_40701	COG0515	serine threonine protein kinase
EJF16_40702	COG0515	serine threonine protein kinase
EJF16_40708	COG3844	kynureninase activity
EJF16_40713	COG3850	Histidine kinase
EJF16_40713	COG4999	Histidine kinase
EJF16_40713	COG2205	protein histidine kinase activity
EJF16_40713	COG3437	response regulator, receiver
EJF16_40715	COG1012	belongs to the aldehyde dehydrogenase family
EJF16_40719	COG0515	serine threonine protein kinase
EJF16_40722	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EJF16_40727	COG0513	Belongs to the DEAD box helicase family
EJF16_40729	COG2271	Major facilitator Superfamily
EJF16_40732	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EJF16_40733	COG0484	heat shock protein binding
EJF16_40738	COG2890	protein-(glutamine-N5) methyltransferase activity
EJF16_40739	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EJF16_40742	COG0833	amino acid
EJF16_40743	COG0833	amino acid
EJF16_40746	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EJF16_40751	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EJF16_40758	COG2271	Major facilitator Superfamily
EJF16_40765	COG2814	Major facilitator Superfamily
EJF16_40770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EJF16_40776	COG1063	alcohol dehydrogenase
EJF16_40781	COG2814	Major facilitator Superfamily
EJF16_40785	COG0833	amino acid
EJF16_40787	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJF16_40787	COG2124	cytochrome p450
EJF16_40788	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EJF16_40789	COG1472	Belongs to the glycosyl hydrolase 3 family
EJF16_40794	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EJF16_40796	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EJF16_40801	COG0436	Aminotransferase
EJF16_40807	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EJF16_40808	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EJF16_40809	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EJF16_40809	COG1017	nitric oxide dioxygenase activity
EJF16_40815	COG0484	heat shock protein binding
EJF16_40823	COG4999	Histidine kinase
EJF16_40823	COG3850	Histidine kinase
EJF16_40823	COG3437	response regulator, receiver
EJF16_40823	COG2205	protein histidine kinase activity
EJF16_40831	COG1012	belongs to the aldehyde dehydrogenase family
EJF16_50011	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EJF16_50015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EJF16_50025	COG0714	Associated with various cellular activities
EJF16_50027	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EJF16_50028	COG0617	tRNA 3'-terminal CCA addition
EJF16_50037	COG2815	serine threonine protein kinase
EJF16_50037	COG0515	serine threonine protein kinase
EJF16_50052	COG1113	amino acid transport
EJF16_50063	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJF16_50064	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EJF16_50082	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJF16_50093	COG0179	Fumarylacetoacetate (FAA) hydrolase
EJF16_50098	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EJF16_50099	COG0037	tRNA processing
EJF16_50113	COG0557	exoribonuclease II activity
EJF16_50114	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJF16_50114	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJF16_50118	COG2815	serine threonine protein kinase
EJF16_50118	COG0515	serine threonine protein kinase
EJF16_50125	COG0705	Rhomboid family
EJF16_50127	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EJF16_50127	COG0517	IMP dehydrogenase activity
EJF16_50129	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJF16_50130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EJF16_50136	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJF16_50136	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJF16_50138	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJF16_50147	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EJF16_50162	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EJF16_50183	COG1643	Atp-dependent helicase
EJF16_50184	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EJF16_50185	COG1218	3'(2'),5'-bisphosphate nucleotidase
EJF16_50196	COG1546	Belongs to the CinA family
EJF16_50196	COG1058	Belongs to the CinA family
EJF16_50200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJF16_50203	COG0515	serine threonine protein kinase
EJF16_50203	COG2815	serine threonine protein kinase
EJF16_50208	COG0459	protein refolding
EJF16_50221	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_50229	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJF16_50233	COG1072	(Pantothenic acid kinase))
EJF16_50234	COG0408	coproporphyrinogen oxidase activity
EJF16_50239	COG0656	L-ascorbic acid biosynthetic process
EJF16_50241	COG0724	RNA recognition motif
EJF16_50245	COG0625	glutathione transferase activity
EJF16_50248	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EJF16_50267	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_50275	COG0481	GTPase activity
EJF16_50279	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EJF16_50280	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
EJF16_50285	COG0513	Belongs to the DEAD box helicase family
EJF16_50291	COG1012	belongs to the aldehyde dehydrogenase family
EJF16_50296	COG0560	Phosphoserine phosphatase
EJF16_50296	COG3830	Belongs to the UPF0237 family
EJF16_50307	COG0596	Alpha beta hydrolase
EJF16_50319	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EJF16_50329	COG0833	amino acid
EJF16_50333	COG0527	aspartate kinase activity
EJF16_50347	COG0405	Gamma-glutamyltransferase
EJF16_50353	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJF16_50355	COG0688	phosphatidylethanolamine metabolic process
EJF16_50374	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJF16_50385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_50387	COG0088	Forms part of the polypeptide exit tunnel
EJF16_50389	COG0058	SHG alpha-glucan phosphorylase activity
EJF16_50393	COG1774	PSP1 C-terminal conserved region
EJF16_50395	COG2815	serine threonine protein kinase
EJF16_50395	COG0515	serine threonine protein kinase
EJF16_50396	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EJF16_50404	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJF16_50414	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJF16_50427	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJF16_50437	COG1132	(ABC) transporter
EJF16_50441	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EJF16_50443	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJF16_50444	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EJF16_50445	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EJF16_50452	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJF16_50462	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJF16_50465	COG1902	pentaerythritol trinitrate reductase activity
EJF16_50466	COG0137	argininosuccinate synthase activity
EJF16_50474	COG0039	L-malate dehydrogenase activity
EJF16_50477	COG0142	geranyltranstransferase activity
EJF16_50478	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EJF16_50479	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EJF16_50495	COG1448	Aminotransferase
EJF16_50498	COG0039	L-malate dehydrogenase activity
EJF16_50505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EJF16_50507	COG0473	3-isopropylmalate dehydrogenase activity
EJF16_50508	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EJF16_50508	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EJF16_50510	COG0123	including yeast histone deacetylase and acetoin utilization protein
EJF16_50527	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EJF16_50529	COG0523	cobalamin synthesis protein
EJF16_50539	COG0515	serine threonine protein kinase
EJF16_50539	COG2815	serine threonine protein kinase
EJF16_50543	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EJF16_50550	COG0513	Belongs to the DEAD box helicase family
EJF16_50558	COG0228	four-way junction DNA binding
EJF16_50566	COG0003	Pfam Anion-transporting ATPase
EJF16_50571	COG0513	Belongs to the DEAD box helicase family
EJF16_50572	COG0101	tRNA pseudouridine synthase activity
EJF16_50578	COG1252	NADH dehydrogenase
EJF16_50592	COG2046	Belongs to the sulfate adenylyltransferase family
EJF16_50592	COG0529	Catalyzes the synthesis of activated sulfate
EJF16_50610	COG3118	belongs to the thioredoxin family
EJF16_50612	COG4221	oxidoreductase activity
EJF16_50618	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_50619	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EJF16_50620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EJF16_50633	COG0484	heat shock protein binding
EJF16_50649	COG1482	cell wall glycoprotein biosynthetic process
EJF16_50651	COG0489	protein tyrosine kinase activity
EJF16_50665	COG0367	asparagine synthase
EJF16_50683	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJF16_50697	COG0833	amino acid
EJF16_50708	COG1185	polyribonucleotide nucleotidyltransferase activity
EJF16_50712	COG1111	helicase
EJF16_50712	COG1205	dead DEAH box helicase
EJF16_50716	COG0443	Heat shock 70 kDa protein
EJF16_50718	COG0833	amino acid
EJF16_50719	COG0833	amino acid
EJF16_50732	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EJF16_50736	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EJF16_50737	COG1902	pentaerythritol trinitrate reductase activity
EJF16_60003	COG2814	Major facilitator Superfamily
EJF16_60004	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EJF16_60005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJF16_60008	COG1085	galactose-1-phosphate uridylyltransferase
EJF16_60010	COG4336	lyase activity
EJF16_60015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJF16_60018	COG0308	aminopeptidase N
EJF16_60022	COG4285	Biotin-protein ligase, N terminal
EJF16_60024	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EJF16_60029	COG0488	(ABC) transporter
EJF16_60049	COG0215	cysteine-tRNA ligase activity
EJF16_60083	COG0515	serine threonine protein kinase
EJF16_60093	COG1999	signal sequence binding
EJF16_60101	COG0488	(ABC) transporter
EJF16_60115	COG1132	(ABC) transporter
EJF16_60116	COG1025	Belongs to the peptidase M16 family
EJF16_60122	COG0402	S-adenosylhomocysteine deaminase activity
EJF16_60129	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EJF16_60130	COG1064	alcohol dehydrogenase
EJF16_60138	COG0307	riboflavin synthase, alpha
EJF16_60140	COG1643	Atp-dependent helicase
EJF16_60146	COG1902	pentaerythritol trinitrate reductase activity
EJF16_60156	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EJF16_60159	COG0477	Major facilitator Superfamily
EJF16_60175	COG2124	cytochrome p450
EJF16_60176	COG0083	homoserine kinase activity
EJF16_60181	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EJF16_60197	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EJF16_60210	COG0123	including yeast histone deacetylase and acetoin utilization protein
EJF16_60211	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EJF16_60212	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EJF16_60240	COG2226	methyltransferase
EJF16_60252	COG1185	polyribonucleotide nucleotidyltransferase activity
EJF16_60260	COG0287	Prephenate dehydrogenase
EJF16_60263	COG0484	heat shock protein binding
EJF16_60268	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EJF16_60283	COG0513	Belongs to the DEAD box helicase family
EJF16_60284	COG1113	amino acid transport
EJF16_60287	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EJF16_60305	COG0563	adenylate kinase activity
EJF16_60315	COG2119	membrane
EJF16_60317	COG1064	alcohol dehydrogenase
EJF16_60321	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJF16_60326	COG0285	dihydrofolate synthase activity
EJF16_60328	COG2815	serine threonine protein kinase
EJF16_60328	COG0515	serine threonine protein kinase
EJF16_60331	COG3265	gluconokinase activity
EJF16_60334	COG0183	Belongs to the thiolase family
EJF16_60338	COG0515	serine threonine protein kinase
EJF16_60338	COG3064	Membrane
EJF16_60338	COG4991	sh3 domain protein
EJF16_60341	COG0181	hydroxymethylbilane synthase activity
EJF16_60345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EJF16_60348	COG0039	L-malate dehydrogenase activity
EJF16_60350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EJF16_60360	COG0515	serine threonine protein kinase
EJF16_60360	COG0457	Tetratricopeptide repeat
EJF16_60361	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJF16_60365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EJF16_60372	COG0386	Belongs to the glutathione peroxidase family
EJF16_60375	COG0833	amino acid
EJF16_60380	COG0354	folic acid binding
EJF16_60386	COG0049	tRNA binding
EJF16_60388	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_60395	COG5277	cytoskeleton organization
EJF16_60396	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EJF16_60412	COG1643	Atp-dependent helicase
EJF16_60413	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EJF16_60436	COG0529	Catalyzes the synthesis of activated sulfate
EJF16_60437	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EJF16_60446	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EJF16_60448	COG4285	Biotin-protein ligase, N terminal
EJF16_60452	COG0308	aminopeptidase N
EJF16_60454	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJF16_70014	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EJF16_70029	COG0681	Belongs to the peptidase S26 family
EJF16_70042	COG2815	serine threonine protein kinase
EJF16_70042	COG0515	serine threonine protein kinase
EJF16_70048	COG1741	Belongs to the pirin family
EJF16_70055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EJF16_70055	COG1648	precorrin-2 dehydrogenase activity
EJF16_70072	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EJF16_70081	COG0519	Catalyzes the synthesis of GMP from XMP
EJF16_70081	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EJF16_70082	COG0736	holo-[acyl-carrier-protein] synthase activity
EJF16_70088	COG0557	exoribonuclease II activity
EJF16_70093	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EJF16_70094	COG0417	DNA replication proofreading
EJF16_70097	COG0038	chloride channel
EJF16_70113	COG0563	adenylate kinase activity
EJF16_70117	COG0281	malic enzyme
EJF16_70118	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EJF16_70133	COG0477	Major facilitator Superfamily
EJF16_70146	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJF16_70156	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJF16_70163	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EJF16_70168	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EJF16_70168	COG3266	domain, Protein
EJF16_70169	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJF16_70173	COG0590	tRNA wobble adenosine to inosine editing
EJF16_70179	COG0052	Belongs to the universal ribosomal protein uS2 family
EJF16_70186	COG0515	serine threonine protein kinase
EJF16_70203	COG0477	Major facilitator Superfamily
EJF16_70203	COG2814	Major facilitator Superfamily
EJF16_70244	COG0012	GTP binding
EJF16_70251	COG0473	3-isopropylmalate dehydrogenase activity
EJF16_70252	COG1104	cysteine desulfurase activity
EJF16_70260	COG0484	heat shock protein binding
EJF16_70261	COG4221	oxidoreductase activity
EJF16_70265	COG2815	serine threonine protein kinase
EJF16_70265	COG0515	serine threonine protein kinase
EJF16_70268	COG0194	GDP metabolic process
EJF16_70272	COG2217	Heavy metal translocating P-type atpase
EJF16_70277	COG0515	serine threonine protein kinase
EJF16_70278	COG2130	NADP-dependent
EJF16_70279	COG2130	NADP-dependent
EJF16_70288	COG0038	chloride channel
EJF16_70298	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EJF16_70304	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EJF16_70315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EJF16_70318	COG1785	Belongs to the alkaline phosphatase family
EJF16_70319	COG2814	Major facilitator Superfamily
EJF16_70332	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EJF16_70333	COG1648	precorrin-2 dehydrogenase activity
EJF16_70333	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EJF16_70346	COG0494	nUDIX hydrolase
EJF16_70349	COG2814	Major facilitator Superfamily
EJF16_70363	COG0415	Belongs to the DNA photolyase family
EJF16_80007	COG0142	geranyltranstransferase activity
EJF16_80016	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EJF16_80025	COG2175	clavaminate synthase activity
EJF16_80028	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EJF16_80033	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EJF16_80035	COG2217	Heavy metal translocating P-type atpase
EJF16_80048	COG0076	glutamate decarboxylase activity
EJF16_80055	COG0445	tRNA wobble uridine modification
EJF16_80059	COG0157	Belongs to the NadC ModD family
EJF16_80063	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EJF16_80069	COG2815	serine threonine protein kinase
EJF16_80069	COG0515	serine threonine protein kinase
EJF16_80076	COG2815	serine threonine protein kinase
EJF16_80076	COG0515	serine threonine protein kinase
EJF16_80088	COG0443	Heat shock 70 kDa protein
EJF16_80089	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJF16_80089	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJF16_80092	COG0004	ammonium transporteR
EJF16_80094	COG0488	(ABC) transporter
EJF16_80103	COG0666	response to abiotic stimulus
EJF16_80113	COG2814	Major facilitator Superfamily
EJF16_80118	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EJF16_80121	COG1914	H( )-stimulated, divalent metal cation uptake system
EJF16_80122	COG0515	serine threonine protein kinase
EJF16_80124	COG0222	ribosome binding
EJF16_80127	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EJF16_80128	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EJF16_80129	COG0277	FAD linked oxidase domain protein
EJF16_80131	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EJF16_80132	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJF16_80139	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EJF16_80140	COG0473	3-isopropylmalate dehydrogenase activity
EJF16_80145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJF16_80154	COG1034	ATP synthesis coupled electron transport
EJF16_80172	COG0753	catalase activity
EJF16_80177	COG0167	dihydroorotate dehydrogenase activity
EJF16_80193	COG0515	serine threonine protein kinase
EJF16_80193	COG2815	serine threonine protein kinase
EJF16_80213	COG0515	serine threonine protein kinase
EJF16_80219	COG2255	four-way junction helicase activity
EJF16_80228	COG0833	amino acid
EJF16_80229	COG0833	amino acid
EJF16_80233	COG0842	Transport permease protein
EJF16_80233	COG1716	ATPase activity
EJF16_80233	COG1131	(ABC) transporter
EJF16_80236	COG0515	serine threonine protein kinase
EJF16_80236	COG2815	serine threonine protein kinase
EJF16_80250	COG0006	proline dipeptidase activity
EJF16_80256	COG1119	ATPase activity
EJF16_80257	COG0156	8-amino-7-oxononanoate synthase activity
EJF16_80261	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EJF16_80262	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EJF16_80265	COG0285	dihydrofolate synthase activity
EJF16_80270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJF16_80289	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EJF16_80292	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EJF16_80292	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EJF16_80300	COG1444	tRNA N-acetyltransferase activity
EJF16_80301	COG1965	Belongs to the frataxin family
EJF16_80308	COG1253	flavin adenine dinucleotide binding
EJF16_80316	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases