NPD12_3250 daa042bf589aa871854185004fc3df94 231 SUPERFAMILY SSF52540 2 219 3.99E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3250 daa042bf589aa871854185004fc3df94 231 Gene3D G3DSA:3.40.50.300 1 230 2.0E-58 T 12-10-2018 NPD12_3250 daa042bf589aa871854185004fc3df94 231 SMART SM00382 26 213 7.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3250 daa042bf589aa871854185004fc3df94 231 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3250 daa042bf589aa871854185004fc3df94 231 Pfam PF00005 ABC transporter 17 155 7.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2766 2b3978583c5ddfd1205356ca4039c7df 812 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 7 110 1.9E-19 T 12-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 NPD12_2766 2b3978583c5ddfd1205356ca4039c7df 812 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 498 797 1.3E-37 T 12-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 NPD12_1977 2412bade57c8c840a24b454f2fdc71ee 103 Pfam PF01906 Putative heavy-metal-binding 1 101 1.1E-34 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 NPD12_1977 2412bade57c8c840a24b454f2fdc71ee 103 SUPERFAMILY SSF117782 1 103 1.44E-32 T 12-10-2018 IPR035439 UPF0145 domain superfamily NPD12_1977 2412bade57c8c840a24b454f2fdc71ee 103 Gene3D G3DSA:3.30.110.70 1 103 6.7E-27 T 12-10-2018 NPD12_1977 2412bade57c8c840a24b454f2fdc71ee 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 102 22.926 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 PIRSF PIRSF500136 7 438 1.9E-168 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 Gene3D G3DSA:3.40.50.720 215 437 1.6E-64 T 12-10-2018 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 18 195 5.8E-45 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 SUPERFAMILY SSF48179 215 308 1.31E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 Gene3D G3DSA:3.40.50.720 1 212 4.8E-69 T 12-10-2018 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 SUPERFAMILY SSF51735 18 208 1.48E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 334 426 7.1E-23 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 SUPERFAMILY SSF52413 318 425 4.58E-26 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 216 306 3.4E-28 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 SMART SM00984 333 427 1.5E-31 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 18 423 3.8E-135 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 NPD12_3217 604469cf32ed005c5b2d2b15288659c6 438 PIRSF PIRSF000124 17 437 6.4E-69 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 PRINTS PR01576 Peptide deformylase signature 34 63 4.9E-26 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 PRINTS PR01576 Peptide deformylase signature 99 117 4.9E-26 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 PRINTS PR01576 Peptide deformylase signature 87 98 4.9E-26 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 PRINTS PR01576 Peptide deformylase signature 118 147 4.9E-26 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 Hamap MF_00163 Peptide deformylase [def]. 2 149 25.267 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 PIRSF PIRSF004749 1 148 2.0E-43 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 9 146 1.3E-41 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 Gene3D G3DSA:3.90.45.10 1 149 5.4E-47 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 SUPERFAMILY SSF56420 3 146 5.1E-48 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_2412 3a1b6940f1f472dc7756c8a39efb4889 150 Pfam PF01327 Polypeptide deformylase 4 145 6.3E-42 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 SUPERFAMILY SSF52540 78 354 7.73E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 PIRSF PIRSF039114 1 461 9.3E-243 T 12-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 SUPERFAMILY SSF47917 361 420 3.92E-6 T 12-10-2018 NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 Gene3D G3DSA:3.40.50.12240 1 458 1.8E-186 T 12-10-2018 NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 3.3E-67 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 458 60.087 T 12-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 74 4.6E-10 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2672 d86f3e1b1227668c795808719a50aa64 461 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2949 d2d5450600259ae0e899b43f03afe34c 352 Gene3D G3DSA:1.20.58.2180 172 341 1.3E-61 T 12-10-2018 NPD12_2949 d2d5450600259ae0e899b43f03afe34c 352 Gene3D G3DSA:3.40.50.1980 197 294 1.3E-61 T 12-10-2018 NPD12_2949 d2d5450600259ae0e899b43f03afe34c 352 Pfam PF01497 Periplasmic binding protein 104 286 3.9E-17 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_2949 d2d5450600259ae0e899b43f03afe34c 352 Gene3D G3DSA:3.40.50.1980 34 167 8.0E-43 T 12-10-2018 NPD12_2949 d2d5450600259ae0e899b43f03afe34c 352 SUPERFAMILY SSF53807 40 348 9.03E-53 T 12-10-2018 NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 Pfam PF13167 GTP-binding GTPase N-terminal 190 278 4.4E-32 T 12-10-2018 IPR025121 GTPase HflX, N-terminal NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 362 531 3.2E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 Hamap MF_00900 GTPase HflX [hflX]. 193 563 47.849 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 Gene3D G3DSA:3.40.50.300 361 538 4.9E-40 T 12-10-2018 NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 Gene3D G3DSA:3.40.50.11060 182 304 1.8E-39 T 12-10-2018 NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 Pfam PF16360 GTP-binding GTPase Middle Region 280 358 2.3E-29 T 12-10-2018 IPR032305 GTP-binding protein, middle domain NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 189 534 1.7E-139 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 Pfam PF01926 50S ribosome-binding GTPase 363 491 2.8E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_3189 02adb014d123aadba31aea18b7e1f954 594 SUPERFAMILY SSF52540 362 560 5.2E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 346 2.8E-146 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 Pfam PF00117 Glutamine amidotransferase class-I 173 346 1.5E-47 T 12-10-2018 IPR017926 Glutamine amidotransferase NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00097 Anthranilate synthase component II signature 213 222 1.3E-7 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00097 Anthranilate synthase component II signature 323 336 1.3E-7 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00097 Anthranilate synthase component II signature 240 251 1.3E-7 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 4.1E-35 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 4.1E-35 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 4.1E-35 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 4.1E-35 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 4.1E-35 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 Gene3D G3DSA:3.50.30.20 1 148 8.5E-57 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 Gene3D G3DSA:3.40.50.880 171 348 3.2E-37 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00096 Glutamine amidotransferase superfamily signature 323 336 1.3E-12 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 1.3E-12 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 PRINTS PR00096 Glutamine amidotransferase superfamily signature 240 251 1.3E-12 T 12-10-2018 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 SMART SM01097 1 131 4.2E-88 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 348 47.065 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 SUPERFAMILY SSF52317 145 348 1.02E-60 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 SUPERFAMILY SSF52021 1 146 8.11E-57 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1994 c6041490ea3763dd9e644114eb82bf4b 349 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 6.2E-53 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 Gene3D G3DSA:1.10.10.60 58 109 6.9E-16 T 12-10-2018 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 SUPERFAMILY SSF46689 5 55 1.25E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 7.3E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 7.3E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 Gene3D G3DSA:1.10.10.60 2 57 4.0E-17 T 12-10-2018 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 SUPERFAMILY SSF46689 57 105 9.86E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 Pfam PF12833 Helix-turn-helix domain 27 105 3.3E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_3519 e308565d5c81757f14eaba8418298fb9 135 SMART SM00342 21 104 8.0E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_3566 dd6ad75f7332be26ea22785be6a21d38 86 Gene3D G3DSA:3.40.50.10310 2 83 1.8E-12 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 NPD12_3566 dd6ad75f7332be26ea22785be6a21d38 86 Pfam PF02633 Creatinine amidohydrolase 8 77 9.5E-12 T 12-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 NPD12_3566 dd6ad75f7332be26ea22785be6a21d38 86 SUPERFAMILY SSF102215 6 59 3.27E-8 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 NPD12_3447 dd7fdc31c0bb7bd9bd6fe67336b45df4 302 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 298 8.6E-31 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 NPD12_3447 dd7fdc31c0bb7bd9bd6fe67336b45df4 302 SUPERFAMILY SSF53807 39 301 2.16E-42 T 12-10-2018 NPD12_3447 dd7fdc31c0bb7bd9bd6fe67336b45df4 302 PRINTS PR00691 Adhesin B signature 38 59 4.6E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_3447 dd7fdc31c0bb7bd9bd6fe67336b45df4 302 PRINTS PR00691 Adhesin B signature 82 101 4.6E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_3447 dd7fdc31c0bb7bd9bd6fe67336b45df4 302 PRINTS PR00691 Adhesin B signature 243 260 4.6E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_3447 dd7fdc31c0bb7bd9bd6fe67336b45df4 302 PRINTS PR00691 Adhesin B signature 141 160 4.6E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_3447 dd7fdc31c0bb7bd9bd6fe67336b45df4 302 Gene3D G3DSA:3.40.50.1980 40 195 9.4E-32 T 12-10-2018 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 5 77 3.0E-30 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 6 81 25.204 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 Pfam PF00366 Ribosomal protein S17 11 78 3.0E-33 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 2.3E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 2.3E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 2.3E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 SUPERFAMILY SSF50249 5 83 7.71E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 77 1.3E-36 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3630 65f696882a654cc6ba5f653317482e8b 84 Gene3D G3DSA:2.40.50.140 5 84 2.5E-35 T 12-10-2018 NPD12_3200 97d9e9168f9f01438a9834d09eaef62c 324 Pfam PF01522 Polysaccharide deacetylase 128 252 5.2E-26 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 NPD12_3200 97d9e9168f9f01438a9834d09eaef62c 324 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 96 321 1.3E-102 T 12-10-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA NPD12_3200 97d9e9168f9f01438a9834d09eaef62c 324 SUPERFAMILY SSF88713 121 321 2.25E-58 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_3200 97d9e9168f9f01438a9834d09eaef62c 324 Gene3D G3DSA:3.20.20.370 77 324 1.7E-74 T 12-10-2018 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SUPERFAMILY SSF48108 395 548 5.49E-44 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.1E-81 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 870 1.1E-34 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.9E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.9E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.9E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.9E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.9E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.9E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.9E-63 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Gene3D G3DSA:3.40.50.20 550 660 5.7E-46 T 12-10-2018 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Gene3D G3DSA:3.40.50.20 1 116 8.5E-49 T 12-10-2018 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Gene3D G3DSA:3.30.470.20 119 401 7.8E-124 T 12-10-2018 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Gene3D G3DSA:3.30.470.20 661 932 1.1E-98 T 12-10-2018 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 1049 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Gene3D G3DSA:3.40.50.1380 935 1066 2.3E-38 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1066 13.268 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Pfam PF02142 MGS-like domain 954 1040 7.0E-20 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SUPERFAMILY SSF52335 939 1051 5.36E-31 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1061 12.91 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SUPERFAMILY SSF56059 669 930 5.83E-93 T 12-10-2018 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 543 1.2E-36 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 833 840 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SUPERFAMILY SSF52440 1 126 1.58E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SMART SM01096 420 543 1.4E-60 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SUPERFAMILY SSF56059 128 399 5.66E-106 T 12-10-2018 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SMART SM00851 953 1040 7.8E-29 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 Gene3D G3DSA:1.10.1030.10 403 549 1.2E-41 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_1993 55a371b6d5a6dea709a7efe238362bf7 1068 SUPERFAMILY SSF52440 553 671 1.05E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily NPD12_2095 0ef0a397ff6670498a511a5e565135c1 247 Pfam PF00005 ABC transporter 21 165 1.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2095 0ef0a397ff6670498a511a5e565135c1 247 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2095 0ef0a397ff6670498a511a5e565135c1 247 SUPERFAMILY SSF52540 2 228 4.88E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2095 0ef0a397ff6670498a511a5e565135c1 247 Gene3D G3DSA:3.40.50.300 1 246 9.1E-62 T 12-10-2018 NPD12_2095 0ef0a397ff6670498a511a5e565135c1 247 SMART SM00382 29 214 9.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2483 29872e892937da577182c1eb487285ab 233 SUPERFAMILY SSF52313 6 229 5.62E-93 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily NPD12_2483 29872e892937da577182c1eb487285ab 233 Pfam PF00318 Ribosomal protein S2 9 225 1.2E-97 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2483 29872e892937da577182c1eb487285ab 233 Gene3D G3DSA:1.10.287.610 101 151 2.5E-24 T 12-10-2018 NPD12_2483 29872e892937da577182c1eb487285ab 233 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 227 4.6E-106 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2483 29872e892937da577182c1eb487285ab 233 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 42.338 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2483 29872e892937da577182c1eb487285ab 233 PRINTS PR00395 Ribosomal protein S2 signature 197 211 9.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2483 29872e892937da577182c1eb487285ab 233 PRINTS PR00395 Ribosomal protein S2 signature 87 104 9.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2483 29872e892937da577182c1eb487285ab 233 PRINTS PR00395 Ribosomal protein S2 signature 159 176 9.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2483 29872e892937da577182c1eb487285ab 233 PRINTS PR00395 Ribosomal protein S2 signature 37 46 9.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2483 29872e892937da577182c1eb487285ab 233 PRINTS PR00395 Ribosomal protein S2 signature 6 24 9.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2483 29872e892937da577182c1eb487285ab 233 PRINTS PR00395 Ribosomal protein S2 signature 176 187 9.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2483 29872e892937da577182c1eb487285ab 233 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 506 626 1.8E-44 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 SUPERFAMILY SSF55604 416 487 1.57E-17 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 568 580 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 Pfam PF02378 Phosphotransferase system, EIIC 12 331 4.0E-64 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 Gene3D G3DSA:3.30.1360.60 410 491 5.2E-23 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 505 628 7.8E-48 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 Pfam PF00367 phosphotransferase system, EIIB 419 450 3.0E-12 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 SUPERFAMILY SSF51261 495 647 7.32E-51 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 395 474 9.5E-14 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 NPD12_2787 00953329d94dcc4afdfcede0e7d9184a 651 Gene3D G3DSA:2.70.70.10 495 650 1.2E-53 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_3290 954e4df639a009c8bfb2912d93ad14ad 231 Pfam PF03734 L,D-transpeptidase catalytic domain 44 149 5.2E-21 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 NPD12_3290 954e4df639a009c8bfb2912d93ad14ad 231 Gene3D G3DSA:1.10.101.10 158 228 7.2E-13 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_3290 954e4df639a009c8bfb2912d93ad14ad 231 SUPERFAMILY SSF141523 40 150 1.31E-31 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_3290 954e4df639a009c8bfb2912d93ad14ad 231 SUPERFAMILY SSF47090 160 226 1.79E-13 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_3290 954e4df639a009c8bfb2912d93ad14ad 231 Gene3D G3DSA:2.40.440.10 36 150 1.6E-36 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_3290 954e4df639a009c8bfb2912d93ad14ad 231 Pfam PF01471 Putative peptidoglycan binding domain 169 212 4.9E-9 T 12-10-2018 IPR002477 Peptidoglycan binding-like NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 Pfam PF00190 Cupin 186 303 2.9E-18 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 Pfam PF00190 Cupin 17 146 1.3E-18 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 2 331 8.0E-145 T 12-10-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 SMART SM00835 185 325 2.5E-20 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 SMART SM00835 7 149 7.3E-18 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 Gene3D G3DSA:2.60.120.10 13 186 4.7E-136 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 Gene3D G3DSA:2.60.120.10 2 328 4.7E-136 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1043 0d00c1ba9cf1e74468a8c2dcc6e16de6 347 SUPERFAMILY SSF51182 2 330 2.12E-88 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 SUPERFAMILY SSF46894 129 227 1.08E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 7.7E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 SMART SM00448 3 113 2.6E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 Gene3D G3DSA:1.10.10.10 128 229 1.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 Pfam PF00072 Response regulator receiver domain 5 113 1.8E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 Gene3D G3DSA:3.40.50.2300 1 124 1.0E-31 T 12-10-2018 NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 SMART SM00862 151 226 2.7E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_482 f2857f53f2c5b399ff43eb8716802216 230 SUPERFAMILY SSF52172 2 124 6.4E-35 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 17 127 2.3E-45 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 14 458 2.7E-181 T 12-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 PRINTS PR00419 Adrenodoxin reductase family signature 282 296 5.6E-19 T 12-10-2018 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 PRINTS PR00419 Adrenodoxin reductase family signature 140 162 5.6E-19 T 12-10-2018 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 PRINTS PR00419 Adrenodoxin reductase family signature 206 216 5.6E-19 T 12-10-2018 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 PRINTS PR00419 Adrenodoxin reductase family signature 163 176 5.6E-19 T 12-10-2018 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 SUPERFAMILY SSF51971 138 391 3.65E-67 T 12-10-2018 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 139 446 5.2E-35 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 SUPERFAMILY SSF46548 5 149 1.57E-35 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 Gene3D G3DSA:3.50.50.60 139 277 1.2E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 Gene3D G3DSA:3.50.50.60 278 461 5.0E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3432 5e457228d3314d0e0b9765de72cad19b 461 Gene3D G3DSA:1.10.1060.10 2 138 6.6E-43 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 SUPERFAMILY SSF54862 145 226 1.6E-17 T 12-10-2018 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 204 215 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 SUPERFAMILY SSF56014 101 305 4.3E-34 T 12-10-2018 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 TIGRFAM TIGR02912 sulfite_red_C: sulfite reductase, subunit C 2 315 1.6E-185 T 12-10-2018 IPR014261 Sulphite reductase, subunit C NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 Gene3D G3DSA:3.90.480.20 4 101 2.5E-10 T 12-10-2018 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 20 79 5.9E-16 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 Gene3D G3DSA:3.30.70.20 161 226 2.6E-11 T 12-10-2018 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 SUPERFAMILY SSF55124 17 80 1.96E-17 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 98 299 4.9E-28 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 PRINTS PR00397 Sirohaem Fe-binding site signature 102 120 1.1E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 PRINTS PR00397 Sirohaem Fe-binding site signature 143 161 1.1E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 Pfam PF13187 4Fe-4S dicluster domain 171 218 2.6E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1145 3d2c6667d07ef2c032a362a9e60f33f5 321 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 143 159 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 SUPERFAMILY SSF46894 131 228 9.07E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 Pfam PF00072 Response regulator receiver domain 5 113 1.0E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 7.7E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 Gene3D G3DSA:3.40.50.2300 1 124 6.6E-32 T 12-10-2018 NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 Gene3D G3DSA:1.10.10.10 125 230 7.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 SUPERFAMILY SSF52172 3 119 1.71E-34 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 SMART SM00862 152 227 4.7E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1658 1cdd4da01a997f978b458da1b05ac2da 233 SMART SM00448 3 113 2.3E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Gene3D G3DSA:3.30.559.10 206 434 1.3E-85 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Gene3D G3DSA:2.40.50.100 5 101 9.3E-27 T 12-10-2018 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 SUPERFAMILY SSF47005 117 162 9.02E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Gene3D G3DSA:4.10.320.10 165 205 2.1E-8 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Gene3D G3DSA:4.10.320.10 114 164 4.7E-15 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Pfam PF02817 e3 binding domain 167 199 1.2E-6 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Pfam PF02817 e3 binding domain 123 157 1.8E-11 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 215 435 2.7E-79 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 SUPERFAMILY SSF52777 216 436 4.27E-78 T 12-10-2018 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 SUPERFAMILY SSF47005 161 203 6.15E-6 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 Pfam PF00364 Biotin-requiring enzyme 7 76 5.2E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment NPD12_1872 273245f7d9ec481a70eb3c9d3828027c 436 SUPERFAMILY SSF51230 6 88 1.96E-23 T 12-10-2018 IPR011053 Single hybrid motif NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 SUPERFAMILY SSF53756 370 544 2.04E-13 T 12-10-2018 NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 Gene3D G3DSA:3.90.550.10 5 227 2.2E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 Gene3D G3DSA:3.40.50.2000 359 491 3.4E-36 T 12-10-2018 NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 Pfam PF02348 Cytidylyltransferase 8 134 8.8E-23 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 Gene3D G3DSA:3.40.50.11190 228 354 2.2E-10 T 12-10-2018 NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 SUPERFAMILY SSF53448 6 227 2.07E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 380 535 3.0E-9 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 NPD12_2729 73a60fd1be4a6d2cf28966b194553079 553 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 226 473 1.8E-45 T 12-10-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Gene3D G3DSA:3.30.200.20 1 89 2.0E-29 T 12-10-2018 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Pfam PF00069 Protein kinase domain 10 258 2.8E-56 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Gene3D G3DSA:1.10.510.10 91 281 2.8E-55 T 12-10-2018 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 SMART SM00220 10 267 1.8E-72 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Gene3D G3DSA:3.30.10.20 441 508 2.0E-19 T 12-10-2018 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Gene3D G3DSA:3.30.10.20 510 574 6.7E-11 T 12-10-2018 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Gene3D G3DSA:3.30.10.20 371 440 9.9E-15 T 12-10-2018 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 SMART SM00740 508 576 3.8E-7 T 12-10-2018 IPR005543 PASTA domain NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 SMART SM00740 439 505 5.6E-13 T 12-10-2018 IPR005543 PASTA domain NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 SMART SM00740 372 438 2.4E-16 T 12-10-2018 IPR005543 PASTA domain NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 SUPERFAMILY SSF56112 6 264 6.61E-83 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 SUPERFAMILY SSF54184 375 437 3.53E-6 T 12-10-2018 NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Pfam PF03793 PASTA domain 376 437 2.8E-12 T 12-10-2018 IPR005543 PASTA domain NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Pfam PF03793 PASTA domain 442 504 6.9E-15 T 12-10-2018 IPR005543 PASTA domain NPD12_2551 eb77d658b675a0d220101d8e5a141ab0 654 Pfam PF03793 PASTA domain 513 576 1.7E-12 T 12-10-2018 IPR005543 PASTA domain NPD12_2715 690da50bc9d4f56dd52dbae3fb63220b 133 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 14 130 2.9E-27 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 NPD12_2715 690da50bc9d4f56dd52dbae3fb63220b 133 PIRSF PIRSF002889 4 133 5.8E-35 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 NPD12_2715 690da50bc9d4f56dd52dbae3fb63220b 133 Pfam PF00460 Flagella basal body rod protein 28 43 8.5E-6 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 151 6.0E-22 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 SMART SM00662 20 227 5.9E-94 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 SUPERFAMILY SSF56553 50 171 7.06E-40 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 Gene3D G3DSA:2.170.120.12 50 170 1.4E-87 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 312 3.5E-120 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 Gene3D G3DSA:3.30.1360.10 16 220 1.4E-87 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 36.418 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 SUPERFAMILY SSF55257 4 225 9.03E-33 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 311 8.0E-23 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 Gene3D G3DSA:1.10.150.20 237 314 6.6E-32 T 12-10-2018 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 6.6E-26 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 SUPERFAMILY SSF47789 247 311 2.35E-23 T 12-10-2018 NPD12_3610 bf3eafaac6e45c455c2d6d264c3b3474 315 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 304 8.0E-28 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 585 52.842 T 12-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 SUPERFAMILY SSF50615 2 71 2.01E-13 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Gene3D G3DSA:3.40.50.300 72 434 2.4E-180 T 12-10-2018 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 SUPERFAMILY SSF52540 179 439 1.17E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 SUPERFAMILY SSF47917 446 533 1.44E-24 T 12-10-2018 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 2.9E-93 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Gene3D G3DSA:2.40.30.20 1 71 2.4E-30 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 202 3.5E-46 T 12-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Gene3D G3DSA:2.40.50.100 115 184 2.4E-180 T 12-10-2018 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 2.4E-14 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2673 baaaa79d0bf36d86170271dad6aadaf7 590 Gene3D G3DSA:1.10.1140.10 435 590 5.0E-53 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 306 96.056 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 Gene3D G3DSA:3.30.465.10 92 218 7.4E-42 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 SUPERFAMILY SSF56194 199 303 7.85E-38 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 Gene3D G3DSA:3.90.78.10 219 306 2.5E-35 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 26 302 1.5E-78 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 SUPERFAMILY SSF56176 7 196 1.26E-48 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 203 301 3.4E-32 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 Pfam PF01565 FAD binding domain 39 165 4.6E-24 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 NPD12_3533 38b5cd2818638d9420e258a588f9a7c4 306 Gene3D G3DSA:3.30.43.10 1 91 1.4E-28 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 NPD12_2196 82e9d4d26c6ef549cce4080c1b657475 411 SUPERFAMILY SSF50978 76 350 2.5E-10 T 12-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 NPD12_2196 82e9d4d26c6ef549cce4080c1b657475 411 Gene3D G3DSA:2.130.10.10 64 357 1.3E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 NPD12_436 85fb0736f5b3f53d5ff9c19aef3f85a5 507 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 413 491 1.6E-14 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 NPD12_436 85fb0736f5b3f53d5ff9c19aef3f85a5 507 Gene3D G3DSA:3.30.1360.60 426 507 4.3E-25 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_436 85fb0736f5b3f53d5ff9c19aef3f85a5 507 Pfam PF02378 Phosphotransferase system, EIIC 16 346 9.7E-61 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_436 85fb0736f5b3f53d5ff9c19aef3f85a5 507 SUPERFAMILY SSF55604 431 505 4.18E-19 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_436 85fb0736f5b3f53d5ff9c19aef3f85a5 507 Pfam PF00367 phosphotransferase system, EIIB 434 466 6.1E-12 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 SUPERFAMILY SSF55874 12 233 8.51E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 SUPERFAMILY SSF56719 421 648 1.26E-73 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 SUPERFAMILY SSF54211 238 411 2.09E-46 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 Gene3D G3DSA:3.30.230.10 240 419 3.3E-56 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 Pfam PF00204 DNA gyrase B 238 411 1.8E-52 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 40 55 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 75 88 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 589 605 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 441 455 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 525 542 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 118 132 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 545 557 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 507 523 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR00418 DNA topoisomerase II family signature 289 302 2.1E-67 T 12-10-2018 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 ProSitePatterns PS00177 DNA topoisomerase II signature. 443 451 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 Pfam PF01751 Toprim domain 441 549 1.6E-16 T 12-10-2018 IPR006171 TOPRIM domain NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 Gene3D G3DSA:3.40.50.670 427 651 2.4E-86 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 SMART SM00387 36 191 5.3E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 Gene3D G3DSA:3.30.565.10 22 239 5.0E-82 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 190 3.8E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 SMART SM00433 40 650 1.6E-262 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 237 259 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 333 349 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 196 211 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 491 500 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 610 622 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 626 642 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 395 415 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 211 224 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 PRINTS PR01159 DNA gyrase subunit B signature 381 395 1.3E-45 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_2805 47df2d7d71e5c70cf10d74d80c0fa675 651 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 586 645 1.6E-27 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_3352 c321a23434b7070525546c85b623e792 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 144 2.6E-46 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 152 301 3.9E-30 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 4 306 35.713 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 4.8E-24 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 4.8E-24 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 4.8E-24 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 4.8E-24 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 5 304 1.2E-103 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 Gene3D G3DSA:3.40.50.1370 5 301 3.8E-109 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 8.4E-37 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 8.4E-37 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 8.4E-37 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 224 233 8.4E-37 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 8.4E-37 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 263 268 8.4E-37 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3352 c321a23434b7070525546c85b623e792 307 SUPERFAMILY SSF53671 2 305 3.54E-100 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 Gene3D G3DSA:3.40.50.1370 132 291 3.8E-109 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_3352 c321a23434b7070525546c85b623e792 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_211 a9495767d39a1d73f02435a7151eba26 482 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 5 368 2.1E-67 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 NPD12_211 a9495767d39a1d73f02435a7151eba26 482 Gene3D G3DSA:3.90.1150.10 318 416 2.6E-5 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_211 a9495767d39a1d73f02435a7151eba26 482 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 412 458 5.0E-7 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 NPD12_211 a9495767d39a1d73f02435a7151eba26 482 Gene3D G3DSA:3.40.640.10 5 283 1.9E-88 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_211 a9495767d39a1d73f02435a7151eba26 482 SUPERFAMILY SSF53383 5 390 4.53E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_211 a9495767d39a1d73f02435a7151eba26 482 Gene3D G3DSA:3.90.105.10 421 478 5.7E-21 T 12-10-2018 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 Gene3D G3DSA:1.10.8.10 149 195 1.1E-12 T 12-10-2018 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 SUPERFAMILY SSF50249 2 63 7.42E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 SUPERFAMILY SSF47781 65 132 1.0E-18 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 Pfam PF07499 RuvA, C-terminal domain 156 196 1.5E-14 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 Gene3D G3DSA:1.10.150.20 67 133 4.9E-23 T 12-10-2018 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 Pfam PF01330 RuvA N terminal domain 2 62 1.1E-15 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 Pfam PF14520 Helix-hairpin-helix domain 72 130 7.7E-17 T 12-10-2018 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 SUPERFAMILY SSF46929 153 196 1.57E-9 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 29.651 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 Gene3D G3DSA:2.40.50.140 1 65 2.8E-17 T 12-10-2018 NPD12_3180 775b787fda9403fb7b0ba36abfc6e8a8 197 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 3 196 5.1E-43 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Gene3D G3DSA:1.20.1110.10 43 296 6.6E-56 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Gene3D G3DSA:3.40.50.1000 297 309 6.6E-56 T 12-10-2018 IPR023214 HAD superfamily NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 503 624 1.4E-27 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 72 483 7.6E-45 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 SUPERFAMILY SSF56784 294 595 1.87E-39 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 509 525 2.2E-11 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 400 418 2.2E-11 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 568 593 2.2E-11 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 537 553 2.2E-11 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Pfam PF00122 E1-E2 ATPase 99 279 1.6E-44 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 SUPERFAMILY SSF81665 3 779 1.57E-64 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Gene3D G3DSA:3.40.1110.10 394 444 1.1E-51 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 469 3.5E-20 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 149 163 3.5E-20 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 300 314 3.5E-20 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 537 556 3.5E-20 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 572 3.5E-20 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 SUPERFAMILY SSF81653 101 196 4.97E-22 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Gene3D G3DSA:2.70.150.10 6 202 6.6E-56 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Gene3D G3DSA:1.20.1110.10 575 783 1.1E-51 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Gene3D G3DSA:3.40.50.1000 445 574 1.1E-51 T 12-10-2018 IPR023214 HAD superfamily NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Pfam PF00702 haloacid dehalogenase-like hydrolase 296 551 5.4E-23 T 12-10-2018 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 Gene3D G3DSA:3.40.1110.10 310 324 6.6E-56 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_1554 dbd0a13762b71a936116fc0eac567986 790 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 302 308 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_2875 99e657d553361c89b79ee80805280007 221 SUPERFAMILY SSF53098 52 215 3.79E-32 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_2875 99e657d553361c89b79ee80805280007 221 Gene3D G3DSA:3.30.420.10 54 214 1.1E-7 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_2875 99e657d553361c89b79ee80805280007 221 Pfam PF00665 Integrase core domain 60 172 3.0E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 NPD12_2875 99e657d553361c89b79ee80805280007 221 Pfam PF13276 HTH-like domain 1 35 3.0E-7 T 12-10-2018 IPR025948 HTH-like domain NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 Hamap MF_00258 Glutamate racemase [murI]. 6 257 32.855 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 242 1.4E-66 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 SUPERFAMILY SSF53681 111 255 1.87E-22 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 205 4.3E-26 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 SUPERFAMILY SSF53681 7 107 4.25E-35 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 Gene3D G3DSA:3.40.50.1860 7 243 7.1E-73 T 12-10-2018 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 Gene3D G3DSA:3.40.50.1860 97 208 7.1E-73 T 12-10-2018 NPD12_33 e02983af8acf76e5f9b24f9167ec74e1 257 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 3.4E-26 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 9.0E-29 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 Gene3D G3DSA:3.30.1340.10 1 85 6.2E-30 T 12-10-2018 IPR035895 HPr-like superfamily NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 SUPERFAMILY SSF55594 1 82 1.44E-24 T 12-10-2018 IPR035895 HPr-like superfamily NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 9.4E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 9.4E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like NPD12_2445 b5c59692397b5b63a9a907a8bfeb5552 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 9.4E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like NPD12_2383 e0f74cd1b366aae37ee55a802f87b1d7 198 Gene3D G3DSA:3.30.1450.10 53 124 8.2E-6 T 12-10-2018 IPR037873 BamE-like NPD12_2383 e0f74cd1b366aae37ee55a802f87b1d7 198 Gene3D G3DSA:3.30.1450.10 127 198 8.7E-6 T 12-10-2018 IPR037873 BamE-like NPD12_2383 e0f74cd1b366aae37ee55a802f87b1d7 198 Pfam PF12978 Domain of Unknown Function with PDB structure (DUF3862) 63 197 1.7E-10 T 12-10-2018 IPR024418 Protein of unknown function DUF3862 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 SUPERFAMILY SSF103039 40 230 2.7E-46 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 305 375 2.0E-25 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 Pfam PF04509 CheC-like family 142 175 4.3E-11 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 Pfam PF04509 CheC-like family 44 79 1.1E-12 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 Gene3D G3DSA:2.30.330.10 292 386 8.4E-35 T 12-10-2018 IPR036429 SpoA-like superfamily NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 302 377 1.7E-30 T 12-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 PRINTS PR00956 Flagellar motor switch protein FliN signature 351 366 1.0E-24 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 PRINTS PR00956 Flagellar motor switch protein FliN signature 338 351 1.0E-24 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 PRINTS PR00956 Flagellar motor switch protein FliN signature 322 338 1.0E-24 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 PRINTS PR00956 Flagellar motor switch protein FliN signature 305 321 1.0E-24 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 SUPERFAMILY SSF101801 301 383 8.76E-25 T 12-10-2018 IPR036429 SpoA-like superfamily NPD12_2776 ca1f181fa7457033e665ee6cab541d2a 386 Gene3D G3DSA:3.40.1550.10 39 237 6.8E-48 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_1868 fe7ed98a94eb9769e826de2e2c866274 121 Gene3D G3DSA:3.30.1330.20 2 121 3.5E-38 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 NPD12_1868 fe7ed98a94eb9769e826de2e2c866274 121 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 5 118 1.4E-24 T 12-10-2018 IPR011719 Conserved hypothetical protein CHP02058 NPD12_1868 fe7ed98a94eb9769e826de2e2c866274 121 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 6 118 4.6E-37 T 12-10-2018 IPR011719 Conserved hypothetical protein CHP02058 NPD12_1845 758270c1b802009f344371f4239321ff 554 Gene3D G3DSA:2.60.40.1180 477 553 3.1E-20 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta NPD12_1845 758270c1b802009f344371f4239321ff 554 Gene3D G3DSA:3.20.20.80 170 476 7.6E-117 T 12-10-2018 NPD12_1845 758270c1b802009f344371f4239321ff 554 PRINTS PR00110 Alpha-amylase signature 193 204 2.0E-6 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 NPD12_1845 758270c1b802009f344371f4239321ff 554 PRINTS PR00110 Alpha-amylase signature 316 328 2.0E-6 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 NPD12_1845 758270c1b802009f344371f4239321ff 554 PRINTS PR00110 Alpha-amylase signature 92 103 2.0E-6 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 NPD12_1845 758270c1b802009f344371f4239321ff 554 SUPERFAMILY SSF51445 4 473 9.29E-151 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1845 758270c1b802009f344371f4239321ff 554 SUPERFAMILY SSF51011 476 552 7.8E-16 T 12-10-2018 NPD12_1845 758270c1b802009f344371f4239321ff 554 Gene3D G3DSA:3.90.400.10 110 169 2.6E-32 T 12-10-2018 NPD12_1845 758270c1b802009f344371f4239321ff 554 SMART SM00642 13 415 1.1E-156 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 NPD12_1845 758270c1b802009f344371f4239321ff 554 Pfam PF00128 Alpha amylase, catalytic domain 28 373 4.6E-117 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 NPD12_1845 758270c1b802009f344371f4239321ff 554 Gene3D G3DSA:3.20.20.80 1 109 3.0E-50 T 12-10-2018 NPD12_2496 5dab411215bac4965fa722c61561cb32 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 9.9E-37 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2496 5dab411215bac4965fa722c61561cb32 82 Pfam PF00886 Ribosomal protein S16 9 67 1.7E-27 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2496 5dab411215bac4965fa722c61561cb32 82 Gene3D G3DSA:3.30.1320.10 1 82 1.5E-36 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2496 5dab411215bac4965fa722c61561cb32 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.874 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2496 5dab411215bac4965fa722c61561cb32 82 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 12-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2496 5dab411215bac4965fa722c61561cb32 82 SUPERFAMILY SSF54565 2 79 3.14E-34 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3184 51e5b4bf8a73c6788b2cd6441c1fefce 220 SMART SM00567 E-Z type HEAT repeats 109 138 0.18 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 NPD12_3184 51e5b4bf8a73c6788b2cd6441c1fefce 220 SMART SM00567 E-Z type HEAT repeats 140 169 6.4 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 NPD12_3184 51e5b4bf8a73c6788b2cd6441c1fefce 220 Pfam PF14493 Helix-turn-helix domain 19 89 4.3E-6 T 12-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 NPD12_3184 51e5b4bf8a73c6788b2cd6441c1fefce 220 Gene3D G3DSA:1.25.10.10 56 219 4.1E-17 T 12-10-2018 IPR011989 Armadillo-like helical NPD12_3184 51e5b4bf8a73c6788b2cd6441c1fefce 220 SUPERFAMILY SSF48371 94 211 1.64E-17 T 12-10-2018 IPR016024 Armadillo-type fold NPD12_3184 51e5b4bf8a73c6788b2cd6441c1fefce 220 Pfam PF13646 HEAT repeats 99 182 1.2E-12 T 12-10-2018 NPD12_1756 3f0d8f0f014074f72b327a9f5d11d25a 163 SUPERFAMILY SSF55826 4 162 1.7E-43 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 NPD12_1756 3f0d8f0f014074f72b327a9f5d11d25a 163 Gene3D G3DSA:3.90.960.10 1 163 7.1E-52 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 NPD12_1756 3f0d8f0f014074f72b327a9f5d11d25a 163 Pfam PF04073 Aminoacyl-tRNA editing domain 24 150 2.8E-29 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 NPD12_766 74ce6a96b9c4e69bc6b152a0271b9d06 226 SMART SM00382 32 220 1.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_766 74ce6a96b9c4e69bc6b152a0271b9d06 226 SUPERFAMILY SSF52540 4 221 7.59E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_766 74ce6a96b9c4e69bc6b152a0271b9d06 226 Gene3D G3DSA:3.40.50.300 2 223 5.3E-60 T 12-10-2018 NPD12_766 74ce6a96b9c4e69bc6b152a0271b9d06 226 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_766 74ce6a96b9c4e69bc6b152a0271b9d06 226 Pfam PF00005 ABC transporter 23 171 8.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3017 1b09a8e299ea7da7e6e478891abd8e94 343 Gene3D G3DSA:1.20.272.10 220 342 4.5E-31 T 12-10-2018 NPD12_3017 1b09a8e299ea7da7e6e478891abd8e94 343 Gene3D G3DSA:3.40.50.300 4 145 2.0E-27 T 12-10-2018 NPD12_3017 1b09a8e299ea7da7e6e478891abd8e94 343 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 18 337 5.3E-51 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 NPD12_3017 1b09a8e299ea7da7e6e478891abd8e94 343 SUPERFAMILY SSF52540 16 215 1.12E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3017 1b09a8e299ea7da7e6e478891abd8e94 343 Pfam PF06144 DNA polymerase III, delta subunit 20 198 3.2E-39 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 NPD12_3017 1b09a8e299ea7da7e6e478891abd8e94 343 SUPERFAMILY SSF48019 222 338 5.67E-22 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 NPD12_3210 78725be306feac56db268e80da6536b4 364 SUPERFAMILY SSF53756 12 361 4.71E-76 T 12-10-2018 NPD12_3210 78725be306feac56db268e80da6536b4 364 Gene3D G3DSA:3.40.50.2000 162 342 1.6E-78 T 12-10-2018 NPD12_3210 78725be306feac56db268e80da6536b4 364 Pfam PF00534 Glycosyl transferases group 1 174 336 1.2E-42 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_3210 78725be306feac56db268e80da6536b4 364 Gene3D G3DSA:3.40.50.2000 21 355 1.6E-78 T 12-10-2018 NPD12_3210 78725be306feac56db268e80da6536b4 364 Pfam PF13477 Glycosyl transferase 4-like 2 140 6.2E-43 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 SUPERFAMILY SSF81653 301 398 1.27E-29 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 SUPERFAMILY SSF55008 1 72 6.41E-20 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 SUPERFAMILY SSF81665 242 795 2.09E-15 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Pfam PF00702 haloacid dehalogenase-like hydrolase 496 711 6.4E-48 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Gene3D G3DSA:3.40.1110.10 509 629 7.4E-103 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 SUPERFAMILY SSF56784 497 804 5.15E-67 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 SUPERFAMILY SSF55008 74 138 5.63E-20 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 67 3.4E-13 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 137 9.3E-15 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Gene3D G3DSA:3.30.70.100 1 69 4.0E-20 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 96 117 3.6E-8 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 213 238 3.6E-8 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 3 28 3.6E-8 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Pfam PF00403 Heavy-metal-associated domain 6 66 1.2E-13 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Pfam PF00403 Heavy-metal-associated domain 76 136 6.1E-14 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Gene3D G3DSA:3.30.70.100 72 137 9.6E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 230 806 5.1E-204 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 633 1.1E-30 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 512 1.1E-30 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 348 362 1.1E-30 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 720 732 1.1E-30 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 654 1.1E-30 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 697 716 1.1E-30 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 500 506 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Gene3D G3DSA:3.40.50.1000 479 749 7.4E-103 T 12-10-2018 IPR023214 HAD superfamily NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Pfam PF00122 E1-E2 ATPase 299 477 2.7E-59 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 212 807 5.9E-191 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 268 287 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 674 691 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 117 137 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 421 435 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 481 496 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 288 306 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 215 234 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 PRINTS PR00943 Copper-transporting ATPase signature 731 745 1.1E-21 T 12-10-2018 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 271 777 3.4E-108 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1552 4c430177a5ee30ffbd325eacad188fbc 811 Gene3D G3DSA:2.70.150.20 291 403 2.2E-42 T 12-10-2018 NPD12_3643 cae8d40f84910e96f578ef896f5430fe 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.326 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 NPD12_3643 cae8d40f84910e96f578ef896f5430fe 156 Gene3D G3DSA:1.10.455.10 2 156 9.8E-62 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily NPD12_3643 cae8d40f84910e96f578ef896f5430fe 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3643 cae8d40f84910e96f578ef896f5430fe 156 SUPERFAMILY SSF47973 7 149 2.22E-60 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily NPD12_3643 cae8d40f84910e96f578ef896f5430fe 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.9E-68 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 NPD12_3643 cae8d40f84910e96f578ef896f5430fe 156 Pfam PF00177 Ribosomal protein S7p/S5e 2 149 7.7E-66 T 12-10-2018 IPR023798 Ribosomal protein S7 domain NPD12_3643 cae8d40f84910e96f578ef896f5430fe 156 PIRSF PIRSF002122 4 156 2.7E-58 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 NPD12_2548 616057e4f0ef676f76a0796bd7e7d728 214 SUPERFAMILY SSF63999 1 131 3.27E-36 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 NPD12_2548 616057e4f0ef676f76a0796bd7e7d728 214 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 207 5.7E-56 T 12-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 NPD12_2548 616057e4f0ef676f76a0796bd7e7d728 214 SMART SM00983 138 205 6.9E-18 T 12-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 NPD12_2548 616057e4f0ef676f76a0796bd7e7d728 214 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 18 127 3.4E-28 T 12-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 NPD12_2548 616057e4f0ef676f76a0796bd7e7d728 214 Gene3D G3DSA:3.40.50.10240 2 213 1.6E-65 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 NPD12_2548 616057e4f0ef676f76a0796bd7e7d728 214 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 145 204 3.8E-12 T 12-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 NPD12_2548 616057e4f0ef676f76a0796bd7e7d728 214 SUPERFAMILY SSF63862 133 207 4.84E-6 T 12-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 Gene3D G3DSA:3.40.50.720 11 98 1.6E-32 T 12-10-2018 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 SUPERFAMILY SSF53244 314 456 1.44E-45 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 SUPERFAMILY SSF51984 10 97 1.44E-27 T 12-10-2018 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 Pfam PF08245 Mur ligase middle domain 116 294 4.4E-32 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 398 7.2E-23 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 Gene3D G3DSA:3.40.1190.10 99 312 9.9E-67 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 10 458 38.85 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 12 453 1.5E-145 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 Gene3D G3DSA:3.90.190.20 313 458 7.1E-57 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 Pfam PF01225 Mur ligase family, catalytic domain 12 110 1.9E-25 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 NPD12_18 34b425d7662789086c24c1528bdf63c7 458 SUPERFAMILY SSF53623 96 312 9.16E-61 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_1732 1545a162f42bd44f05fe18dc39bc00eb 271 Gene3D G3DSA:3.40.190.10 45 266 4.2E-81 T 12-10-2018 NPD12_1732 1545a162f42bd44f05fe18dc39bc00eb 271 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 49 265 5.1E-70 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 NPD12_1732 1545a162f42bd44f05fe18dc39bc00eb 271 SUPERFAMILY SSF53850 43 267 1.71E-69 T 12-10-2018 NPD12_1732 1545a162f42bd44f05fe18dc39bc00eb 271 Pfam PF13531 Bacterial extracellular solute-binding protein 44 266 2.2E-50 T 12-10-2018 NPD12_1732 1545a162f42bd44f05fe18dc39bc00eb 271 PIRSF PIRSF004846 1 270 4.6E-83 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 NPD12_1732 1545a162f42bd44f05fe18dc39bc00eb 271 Gene3D G3DSA:3.40.190.10 122 229 4.2E-81 T 12-10-2018 NPD12_2429 2331be85f5a975343e422c0a555919a8 401 Pfam PF01844 HNH endonuclease 310 352 5.9E-7 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 NPD12_2429 2331be85f5a975343e422c0a555919a8 401 SUPERFAMILY SSF56672 11 202 5.44E-23 T 12-10-2018 NPD12_2429 2331be85f5a975343e422c0a555919a8 401 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 3 132 1.0E-21 T 12-10-2018 IPR000477 Reverse transcriptase domain NPD12_2429 2331be85f5a975343e422c0a555919a8 401 Gene3D G3DSA:3.30.70.270 65 139 3.0E-5 T 12-10-2018 NPD12_2429 2331be85f5a975343e422c0a555919a8 401 Pfam PF08388 Group II intron, maturase-specific domain 152 230 2.3E-17 T 12-10-2018 IPR013597 Group II intron, maturase-specific NPD12_2429 2331be85f5a975343e422c0a555919a8 401 SMART SM00507 297 351 4.2E-8 T 12-10-2018 IPR003615 HNH nuclease NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 SUPERFAMILY SSF56327 173 440 3.41E-93 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 Gene3D G3DSA:3.90.110.10 171 443 1.1E-100 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 SUPERFAMILY SSF51735 4 168 2.4E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 1.9E-51 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 1.9E-51 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 1.9E-51 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 1.9E-51 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 1.9E-51 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 1.9E-51 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 1.9E-51 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 Gene3D G3DSA:3.40.50.720 1 170 3.2E-70 T 12-10-2018 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 12-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 412 2.0E-50 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 NPD12_3505 cb8e43a024336be3a21c750118af7bb5 445 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 1.1E-72 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 16 447 1.0E-158 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 Gene3D G3DSA:3.40.50.12160 15 152 6.7E-35 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 Gene3D G3DSA:3.80.30.20 156 391 3.3E-98 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 SUPERFAMILY SSF102114 155 382 1.02E-64 T 12-10-2018 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 Pfam PF01938 TRAM domain 388 448 7.1E-15 T 12-10-2018 IPR002792 TRAM domain NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 14 450 74.084 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 163 183 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 Pfam PF00919 Uncharacterized protein family UPF0004 16 116 1.2E-28 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 Pfam PF04055 Radical SAM superfamily 163 335 3.6E-33 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 16 448 1.9E-174 T 12-10-2018 NPD12_1951 744d84b80c3c7fe0259244bfc5a13379 450 SMART SM00729 159 377 4.5E-64 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_362 97461f5b57ce4560436a8ee7e09fb88f 231 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 34 231 3.9E-99 T 12-10-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 NPD12_362 97461f5b57ce4560436a8ee7e09fb88f 231 SUPERFAMILY SSF47090 40 103 4.71E-21 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_362 97461f5b57ce4560436a8ee7e09fb88f 231 Gene3D G3DSA:1.10.101.10 33 110 8.0E-22 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_362 97461f5b57ce4560436a8ee7e09fb88f 231 Gene3D G3DSA:2.40.10.420 196 231 7.9E-20 T 12-10-2018 NPD12_362 97461f5b57ce4560436a8ee7e09fb88f 231 Pfam PF01471 Putative peptidoglycan binding domain 46 101 5.8E-18 T 12-10-2018 IPR002477 Peptidoglycan binding-like NPD12_362 97461f5b57ce4560436a8ee7e09fb88f 231 Pfam PF07486 Cell Wall Hydrolase 132 230 2.3E-28 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 NPD12_362 97461f5b57ce4560436a8ee7e09fb88f 231 Gene3D G3DSA:1.10.10.2520 116 195 1.6E-31 T 12-10-2018 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 Gene3D G3DSA:3.10.310.10 3 269 3.1E-92 T 12-10-2018 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 Gene3D G3DSA:3.10.310.10 123 263 3.1E-92 T 12-10-2018 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 SUPERFAMILY SSF54506 1 131 1.83E-38 T 12-10-2018 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 271 2.4E-81 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 SUPERFAMILY SSF54506 143 272 2.44E-38 T 12-10-2018 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 273 35.199 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 Pfam PF01678 Diaminopimelate epimerase 156 264 2.2E-17 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 NPD12_2077 c15615c96bddb1c8043036867fd67c3a 273 Pfam PF01678 Diaminopimelate epimerase 3 126 4.3E-32 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 NPD12_440 8c70689545c976397115394eafc2b632 232 Pfam PF00072 Response regulator receiver domain 4 112 7.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_440 8c70689545c976397115394eafc2b632 232 Gene3D G3DSA:3.40.50.2300 2 127 2.5E-28 T 12-10-2018 NPD12_440 8c70689545c976397115394eafc2b632 232 SUPERFAMILY SSF52172 3 118 2.7E-32 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_440 8c70689545c976397115394eafc2b632 232 SMART SM00862 149 224 9.4E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_440 8c70689545c976397115394eafc2b632 232 SMART SM00448 2 112 3.7E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_440 8c70689545c976397115394eafc2b632 232 SUPERFAMILY SSF46894 125 225 3.97E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_440 8c70689545c976397115394eafc2b632 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 2.6E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_440 8c70689545c976397115394eafc2b632 232 Gene3D G3DSA:1.10.10.10 128 232 1.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 SUPERFAMILY SSF50621 239 384 1.85E-48 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 Gene3D G3DSA:2.40.37.10 9 375 3.9E-128 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 Pfam PF01168 Alanine racemase, N-terminal domain 12 232 1.7E-63 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 205 232 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 300 317 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 30 46 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 66 84 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 162 173 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 358 371 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 262 277 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 127 139 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 PRINTS PR00992 Alanine racemase signature 279 294 7.8E-54 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 SUPERFAMILY SSF51419 12 247 6.4E-64 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 Gene3D G3DSA:3.20.20.10 14 228 3.9E-128 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 TIGRFAM TIGR00492 alr: alanine racemase 6 376 1.2E-112 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 Pfam PF00842 Alanine racemase, C-terminal domain 246 375 8.1E-44 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 SMART SM01005 246 376 1.4E-64 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 Hamap MF_01201 Alanine racemase. 5 376 32.918 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1899 bdb211bac87646db6b526b224b1b8c97 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 35 45 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.2E-5 T 12-10-2018 NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 372 379 2.2E-5 T 12-10-2018 NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 Gene3D G3DSA:3.50.50.60 5 398 3.8E-130 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 Gene3D G3DSA:2.40.30.10 190 349 3.8E-130 T 12-10-2018 NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 SUPERFAMILY SSF160996 191 350 2.88E-47 T 12-10-2018 NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 Pfam PF03486 HI0933-like protein 3 402 4.9E-135 T 12-10-2018 NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 Gene3D G3DSA:1.10.8.260 268 332 3.8E-130 T 12-10-2018 IPR023166 HI0933-like insert domain superfamily NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 401 5.6E-140 T 12-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like NPD12_1960 ee0f7a2c8d22ef626e4657698b2f06e7 407 SUPERFAMILY SSF51905 3 404 7.14E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 Gene3D G3DSA:1.10.1140.10 346 463 6.3E-56 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 Hamap MF_01347 ATP synthase subunit beta [atpB]. 2 461 58.199 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 Gene3D G3DSA:3.40.50.300 77 345 3.9E-117 T 12-10-2018 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 334 343 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 SUPERFAMILY SSF52540 78 348 1.58E-95 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 74 1.9E-19 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 Gene3D G3DSA:2.40.10.170 3 76 7.3E-28 T 12-10-2018 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 4 461 1.1E-252 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 SUPERFAMILY SSF47917 346 461 3.4E-52 T 12-10-2018 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 343 2.2E-68 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 SMART SM00382 143 328 2.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_311 69d304e59ce16bd1b6b508c51ee20b9f 463 SUPERFAMILY SSF50615 3 75 1.57E-23 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 SUPERFAMILY SSF58014 67 159 1.57E-25 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 ProSitePatterns PS01071 grpE protein signature. 169 212 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 PRINTS PR00773 GrpE protein signature 88 104 2.4E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 PRINTS PR00773 GrpE protein signature 193 212 2.4E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 PRINTS PR00773 GrpE protein signature 116 131 2.4E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 PRINTS PR00773 GrpE protein signature 166 181 2.4E-25 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 Gene3D G3DSA:3.90.20.20 46 158 8.6E-28 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 SUPERFAMILY SSF51064 167 213 1.28E-13 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 Gene3D G3DSA:2.30.22.10 159 214 6.3E-17 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 Hamap MF_01151 Protein GrpE [grpE]. 15 214 19.156 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 NPD12_3009 a5f3f12b5810ad5739f91b69ef5cab6e 214 Pfam PF01025 GrpE 55 213 1.4E-47 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 563 671 8.5E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Gene3D G3DSA:3.30.450.20 9 155 4.0E-5 T 12-10-2018 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 658 671 4.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 613 4.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 652 4.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 627 4.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 SUPERFAMILY SSF47384 438 516 1.96E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Gene3D G3DSA:3.30.450.20 180 305 1.4E-9 T 12-10-2018 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 SMART SM00387 562 674 3.3E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Gene3D G3DSA:3.30.450.20 306 434 4.3E-6 T 12-10-2018 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 SUPERFAMILY SSF55785 187 303 4.38E-5 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Gene3D G3DSA:3.30.565.10 519 683 1.8E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2796 f3853d4951fe958a172d907042035bd8 702 SMART SM00388 448 516 6.4E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Pfam PF00512 His Kinase A (phospho-acceptor) domain 449 516 2.4E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Pfam PF13188 PAS domain 183 214 0.16 T 12-10-2018 IPR000014 PAS domain NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Pfam PF13188 PAS domain 315 379 0.032 T 12-10-2018 IPR000014 PAS domain NPD12_2796 f3853d4951fe958a172d907042035bd8 702 SUPERFAMILY SSF55874 505 670 5.76E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2796 f3853d4951fe958a172d907042035bd8 702 Gene3D G3DSA:1.10.287.130 435 518 3.2E-20 T 12-10-2018 NPD12_3355 fe203d1160a22286a19c1e172c962a78 419 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 76 419 2.6E-91 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_3355 fe203d1160a22286a19c1e172c962a78 419 Gene3D G3DSA:3.40.50.11900 273 419 1.2E-48 T 12-10-2018 NPD12_3355 fe203d1160a22286a19c1e172c962a78 419 Gene3D G3DSA:1.20.1270.370 59 260 1.2E-38 T 12-10-2018 NPD12_3355 fe203d1160a22286a19c1e172c962a78 419 Gene3D G3DSA:3.40.50.11890 69 194 1.2E-38 T 12-10-2018 NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 SUPERFAMILY SSF52172 1 125 1.99E-34 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 SUPERFAMILY SSF46894 126 222 5.95E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 1.3E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 Pfam PF00072 Response regulator receiver domain 4 112 1.6E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 SMART SM00448 2 112 1.8E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 Gene3D G3DSA:1.10.10.10 125 223 3.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 Gene3D G3DSA:3.40.50.2300 1 124 5.6E-32 T 12-10-2018 NPD12_2272 53679eb8ede7373674485b0dd9b20850 223 SMART SM00862 147 222 6.4E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1459 8694ea224675888dc37cb59b06583428 170 SMART SM00530 6 61 1.3E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1459 8694ea224675888dc37cb59b06583428 170 Gene3D G3DSA:1.10.260.40 3 130 1.4E-20 T 12-10-2018 NPD12_1459 8694ea224675888dc37cb59b06583428 170 SUPERFAMILY SSF47413 1 64 3.55E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1459 8694ea224675888dc37cb59b06583428 170 Pfam PF01381 Helix-turn-helix 7 60 4.4E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3218 750a4d444b9164d753e89218daa16534 621 Gene3D G3DSA:3.90.25.30 458 558 6.5E-125 T 12-10-2018 NPD12_3218 750a4d444b9164d753e89218daa16534 621 Gene3D G3DSA:3.40.50.720 293 579 6.5E-125 T 12-10-2018 NPD12_3218 750a4d444b9164d753e89218daa16534 621 Gene3D G3DSA:3.40.50.720 151 277 1.4E-37 T 12-10-2018 NPD12_3218 750a4d444b9164d753e89218daa16534 621 SUPERFAMILY SSF51735 294 557 1.99E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3218 750a4d444b9164d753e89218daa16534 621 Pfam PF13727 CoA-binding domain 72 248 3.9E-12 T 12-10-2018 NPD12_3218 750a4d444b9164d753e89218daa16534 621 Pfam PF02719 Polysaccharide biosynthesis protein 296 578 1.4E-125 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain NPD12_3218 750a4d444b9164d753e89218daa16534 621 SUPERFAMILY SSF53335 113 335 5.98E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 Gene3D G3DSA:3.40.50.2020 76 271 3.2E-50 T 12-10-2018 NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 15 73 7.0E-21 T 12-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 Pfam PF00156 Phosphoribosyl transferase domain 112 261 4.7E-21 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 Gene3D G3DSA:1.10.10.10 2 74 9.8E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 263 5.0E-109 T 12-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 Pfam PF09182 Bacterial purine repressor, N-terminal 6 73 3.6E-29 T 12-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 SUPERFAMILY SSF53271 93 254 2.98E-35 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_17 a0f2a9111f3545291c98dbdff7b60072 271 SUPERFAMILY SSF46785 3 73 2.04E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 SUPERFAMILY SSF54106 7 52 5.36E-12 T 12-10-2018 NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Gene3D G3DSA:2.30.30.40 102 163 1.4E-10 T 12-10-2018 NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 SMART SM00636 170 487 1.6E-7 T 12-10-2018 IPR011583 Chitinase II GO:0008061 NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 SUPERFAMILY SSF54106 54 97 4.71E-11 T 12-10-2018 NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 ProSitePatterns PS01095 Chitinases family 18 active site. 288 296 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 SMART SM00287 99 161 4.2E-7 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Pfam PF01476 LysM domain 9 51 9.2E-16 T 12-10-2018 IPR018392 LysM domain NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Pfam PF01476 LysM domain 55 97 2.3E-13 T 12-10-2018 IPR018392 LysM domain NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Gene3D G3DSA:3.10.350.10 3 53 1.5E-16 T 12-10-2018 IPR036779 LysM domain superfamily NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 SMART SM00257 54 97 2.6E-14 T 12-10-2018 IPR018392 LysM domain NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 SMART SM00257 8 51 1.0E-17 T 12-10-2018 IPR018392 LysM domain NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Gene3D G3DSA:3.20.20.80 215 492 2.1E-73 T 12-10-2018 NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Pfam PF08239 Bacterial SH3 domain 109 155 1.0E-9 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Gene3D G3DSA:3.10.350.10 54 97 5.1E-15 T 12-10-2018 IPR036779 LysM domain superfamily NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Gene3D G3DSA:3.10.50.10 403 458 2.1E-73 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 SUPERFAMILY SSF51445 193 494 4.54E-42 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1397 440e0b8188b47ad4d6b3c45ca47dc3fa 504 Pfam PF00704 Glycosyl hydrolases family 18 253 486 1.8E-25 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 140 155 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 Gene3D G3DSA:3.90.190.20 299 429 1.0E-32 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 Pfam PF08245 Mur ligase middle domain 44 271 2.4E-19 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 Pfam PF02875 Mur ligase family, glutamate ligase domain 296 377 1.1E-10 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 42 65 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 PIRSF PIRSF001563 1 429 1.1E-144 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 427 4.5E-117 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 Gene3D G3DSA:3.40.1190.10 1 296 5.2E-98 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 SUPERFAMILY SSF53623 1 296 1.73E-87 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_3275 ad2c3482b5cb25b8d283f60dc2b0d6ed 429 SUPERFAMILY SSF53244 299 428 3.85E-27 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 412 1.1E-152 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 SUPERFAMILY SSF51246 327 412 1.49E-23 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 SMART SM01210 327 412 3.6E-31 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 7.2E-33 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 SUPERFAMILY SSF56059 102 321 9.9E-52 T 12-10-2018 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Gene3D G3DSA:3.30.1490.20 119 188 2.4E-24 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Gene3D G3DSA:3.40.50.20 1 93 2.0E-33 T 12-10-2018 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 7.8E-72 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Gene3D G3DSA:3.30.470.20 189 326 6.9E-48 T 12-10-2018 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 SMART SM01209 101 293 2.9E-115 T 12-10-2018 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 413 39.241 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Gene3D G3DSA:3.90.600.10 328 413 7.7E-27 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 SUPERFAMILY SSF52440 1 101 6.47E-34 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily NPD12_2926 3d075dd04439b89dd3405d91555ab05d 413 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 413 1.1E-24 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2701 09b9a2ff9e7c96687bc8dccece6ee742 247 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 59 7.4E-20 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain NPD12_2701 09b9a2ff9e7c96687bc8dccece6ee742 247 SUPERFAMILY SSF103088 120 237 1.7E-31 T 12-10-2018 IPR036737 OmpA-like domain superfamily NPD12_2701 09b9a2ff9e7c96687bc8dccece6ee742 247 Gene3D G3DSA:3.30.1330.60 80 247 2.2E-49 T 12-10-2018 IPR036737 OmpA-like domain superfamily NPD12_2701 09b9a2ff9e7c96687bc8dccece6ee742 247 Pfam PF00691 OmpA family 132 231 1.9E-20 T 12-10-2018 IPR006665 OmpA-like domain NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 101 114 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 419 2.2E-66 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 SUPERFAMILY SSF53223 5 184 9.6E-73 T 12-10-2018 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 PIRSF PIRSF000185 3 421 2.3E-160 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 9.2E-34 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 347 358 9.2E-34 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 93 107 9.2E-34 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 9.2E-34 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 SUPERFAMILY SSF51735 182 421 2.33E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 Gene3D G3DSA:3.40.50.10860 38 181 1.0E-64 T 12-10-2018 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 36 163 2.6E-56 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 Gene3D G3DSA:3.40.50.720 182 421 7.4E-83 T 12-10-2018 NPD12_1961 a51546a4a65f8d75601e01bfa2bf8680 421 SMART SM00839 184 419 6.2E-90 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 NPD12_895 08a6626ef719e0c72e115722606b612e 243 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_895 08a6626ef719e0c72e115722606b612e 243 Gene3D G3DSA:3.40.50.300 1 229 5.6E-57 T 12-10-2018 NPD12_895 08a6626ef719e0c72e115722606b612e 243 SUPERFAMILY SSF52540 3 218 7.0E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_895 08a6626ef719e0c72e115722606b612e 243 SMART SM00382 28 205 3.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_895 08a6626ef719e0c72e115722606b612e 243 Pfam PF00005 ABC transporter 19 157 2.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_104 d519d23ffd4b2de26353ba1d79f1d42d 105 Pfam PF12643 MazG-like family 8 94 9.1E-26 T 12-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 PIRSF PIRSF000447 1 412 6.7E-184 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 SMART SM00825 Beta-ketoacyl synthase 5 410 8.4E-16 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 1.1E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 Gene3D G3DSA:3.40.47.10 255 399 2.7E-52 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.1E-60 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 3.0E-194 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 Gene3D G3DSA:3.40.47.10 1 253 4.9E-96 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 SUPERFAMILY SSF53901 213 410 6.31E-71 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_68 3475f96db14738c1fc1a80aa4f6ddd2c 412 SUPERFAMILY SSF53901 2 250 3.84E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 Gene3D G3DSA:3.30.565.10 333 485 6.5E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 Gene3D G3DSA:1.20.1480.50 156 252 6.8E-9 T 12-10-2018 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 Gene3D G3DSA:1.10.287.130 253 330 9.9E-18 T 12-10-2018 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 SUPERFAMILY SSF158472 200 249 6.67E-9 T 12-10-2018 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 SMART SM00304 199 251 2.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 SMART SM00388 259 326 1.0E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 SMART SM00387 375 486 5.7E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 6.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 6.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 6.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 484 3.4E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 SUPERFAMILY SSF55874 316 483 4.58E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 SUPERFAMILY SSF47384 245 327 3.73E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2091 96491a5d8d700a9b2da0f708734d5bf1 486 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 325 8.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 Gene3D G3DSA:1.10.601.10 2 102 2.6E-24 T 12-10-2018 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 PIRSF PIRSF000770 2 250 6.4E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 Pfam PF04542 Sigma-70 region 2 34 100 1.3E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 Pfam PF04545 Sigma-70, region 4 198 246 9.0E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 58 71 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 19 249 3.8E-115 T 12-10-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 28 249 7.4E-83 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 Gene3D G3DSA:1.10.10.10 178 250 1.2E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 SUPERFAMILY SSF88659 106 179 9.16E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 SUPERFAMILY SSF88946 10 102 2.75E-32 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 Pfam PF04539 Sigma-70 region 3 121 185 3.4E-6 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 SUPERFAMILY SSF88659 188 249 3.74E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 Gene3D G3DSA:1.10.10.10 103 155 3.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 249 1.1E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 PRINTS PR00046 Major sigma-70 factor signature 82 90 7.8E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 PRINTS PR00046 Major sigma-70 factor signature 234 245 7.8E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 PRINTS PR00046 Major sigma-70 factor signature 58 71 7.8E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 PRINTS PR00046 Major sigma-70 factor signature 219 234 7.8E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_3196 584f700c8fef21f5c25549eeafb6478b 251 PRINTS PR00046 Major sigma-70 factor signature 202 214 7.8E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_720 e735e40a28cbc7618ce7a82be805c483 302 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 97 189 3.0E-8 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 NPD12_720 e735e40a28cbc7618ce7a82be805c483 302 Gene3D G3DSA:3.40.50.1820 53 301 1.6E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_720 e735e40a28cbc7618ce7a82be805c483 302 SUPERFAMILY SSF53474 44 299 1.16E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Pfam PF03453 MoeA N-terminal region (domain I and II) 12 160 7.9E-28 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 SUPERFAMILY SSF63867 321 395 1.31E-15 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 SUPERFAMILY SSF63882 11 169 2.35E-35 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Gene3D G3DSA:3.40.980.10 169 310 5.3E-79 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Pfam PF00994 Probable molybdopterin binding domain 174 310 1.4E-24 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 171 307 4.9E-30 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Gene3D G3DSA:2.170.190.11 53 135 5.3E-79 T 12-10-2018 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Pfam PF03454 MoeA C-terminal region (domain IV) 324 394 5.4E-16 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 247 280 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Pfam PF12727 PBP superfamily domain 424 608 3.4E-62 T 12-10-2018 IPR024370 PBP domain NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 SUPERFAMILY SSF53218 172 314 3.01E-38 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Gene3D G3DSA:2.40.340.10 321 396 1.4E-19 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Gene3D G3DSA:3.90.105.10 35 168 5.3E-79 T 12-10-2018 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 SUPERFAMILY SSF53850 424 623 1.33E-11 T 12-10-2018 NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 SMART SM00852 174 311 4.2E-36 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2107 d78a5e0fdfdbf39f3f38fd065befb581 634 Gene3D G3DSA:3.40.190.10 487 565 2.4E-5 T 12-10-2018 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 SUPERFAMILY SSF53850 89 293 2.39E-25 T 12-10-2018 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 Gene3D G3DSA:3.40.190.10 92 286 8.2E-24 T 12-10-2018 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 Gene3D G3DSA:3.40.190.10 163 264 8.2E-24 T 12-10-2018 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 Gene3D G3DSA:1.10.10.10 1 90 2.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 SUPERFAMILY SSF46785 1 86 4.45E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.7E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1818 5159c4d280611bea45ab43037e720fd6 296 Pfam PF03466 LysR substrate binding domain 91 290 2.8E-25 T 12-10-2018 IPR005119 LysR, substrate-binding NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 2.5E-46 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 2.5E-46 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 2.5E-46 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 PRINTS PR00086 L-lactate dehydrogenase signature 34 58 2.5E-46 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 PRINTS PR00086 L-lactate dehydrogenase signature 9 33 2.5E-46 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 12 310 9.4E-124 T 12-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 Gene3D G3DSA:3.40.50.720 1 148 5.0E-61 T 12-10-2018 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 PIRSF PIRSF000102 4 316 2.6E-109 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 12-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 Gene3D G3DSA:3.90.110.10 149 316 1.5E-59 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 SUPERFAMILY SSF51735 4 146 9.04E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 3.3E-46 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 7 316 42.031 T 12-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 SUPERFAMILY SSF56327 147 313 3.63E-56 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_1762 036f1cda9c8a38e424e3cf2ae34f2efa 318 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 314 1.0E-34 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 Gene3D G3DSA:2.40.30.30 185 306 2.9E-41 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 Pfam PF06574 FAD synthetase 12 164 2.0E-43 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 Pfam PF01687 Riboflavin kinase 183 303 1.8E-36 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 PIRSF PIRSF004491 1 305 2.0E-98 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 SUPERFAMILY SSF52374 16 178 2.55E-26 T 12-10-2018 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 Gene3D G3DSA:3.40.50.620 2 184 7.5E-49 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 303 1.7E-76 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 SMART SM00904 182 306 4.8E-52 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 NPD12_2462 e6664a731eacb68d1d15072089d4b487 306 SUPERFAMILY SSF82114 173 303 1.48E-43 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 NPD12_1781 86ef1090ff8bad1fc3c3ce317173fe0c 119 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 62 118 8.0E-17 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 NPD12_1781 86ef1090ff8bad1fc3c3ce317173fe0c 119 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 52 1.7E-9 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 NPD12_1781 86ef1090ff8bad1fc3c3ce317173fe0c 119 SMART SM00529 23 119 1.1E-22 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 NPD12_1781 86ef1090ff8bad1fc3c3ce317173fe0c 119 SUPERFAMILY SSF46785 1 61 1.96E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1781 86ef1090ff8bad1fc3c3ce317173fe0c 119 Gene3D G3DSA:1.10.60.10 67 119 4.4E-21 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 NPD12_1781 86ef1090ff8bad1fc3c3ce317173fe0c 119 Gene3D G3DSA:1.10.10.10 2 66 8.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1781 86ef1090ff8bad1fc3c3ce317173fe0c 119 SUPERFAMILY SSF47979 62 118 1.7E-16 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 NPD12_458 5045a3ae74f10156c530952b1b0afee6 215 Pfam PF01081 KDPG and KHG aldolase 8 198 1.4E-37 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 NPD12_458 5045a3ae74f10156c530952b1b0afee6 215 SUPERFAMILY SSF51569 3 209 4.58E-57 T 12-10-2018 NPD12_458 5045a3ae74f10156c530952b1b0afee6 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 8 208 1.3E-48 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 NPD12_458 5045a3ae74f10156c530952b1b0afee6 215 Gene3D G3DSA:3.20.20.70 2 214 5.4E-64 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 7.9E-187 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 Gene3D G3DSA:3.40.1380.20 335 468 7.5E-194 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 SUPERFAMILY SSF52935 322 473 4.71E-43 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 Gene3D G3DSA:3.50.30.10 474 585 1.6E-25 T 12-10-2018 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 Gene3D G3DSA:3.20.20.60 3 334 7.5E-194 T 12-10-2018 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 505 575 6.6E-16 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 ProSitePatterns PS00110 Pyruvate kinase active site signature. 214 226 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 Pfam PF00224 Pyruvate kinase, barrel domain 1 341 1.8E-144 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 470 6.0E-37 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 SUPERFAMILY SSF51621 1 340 2.16E-99 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 Gene3D G3DSA:2.40.33.10 70 167 7.5E-194 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 SUPERFAMILY SSF52009 465 583 2.49E-25 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 PRINTS PR01050 Pyruvate kinase family signature 268 292 2.8E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 PRINTS PR01050 Pyruvate kinase family signature 59 75 2.8E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 PRINTS PR01050 Pyruvate kinase family signature 312 328 2.8E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 PRINTS PR01050 Pyruvate kinase family signature 216 242 2.8E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 PRINTS PR01050 Pyruvate kinase family signature 293 311 2.8E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 PRINTS PR01050 Pyruvate kinase family signature 185 199 2.8E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 PRINTS PR01050 Pyruvate kinase family signature 243 267 2.8E-79 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 NPD12_3527 e7ff8ddee23e7ce55ad3d4115ed61030 585 SUPERFAMILY SSF50800 70 166 4.01E-28 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily NPD12_1457 0047b558c8648e599153ac1289479e5e 356 Gene3D G3DSA:1.10.443.10 162 355 1.7E-43 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 NPD12_1457 0047b558c8648e599153ac1289479e5e 356 Pfam PF00589 Phage integrase family 174 342 3.1E-25 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 NPD12_1457 0047b558c8648e599153ac1289479e5e 356 Pfam PF14657 Arm DNA-binding domain 14 53 7.1E-11 T 12-10-2018 IPR028259 AP2-like integrase, N-terminal domain NPD12_1457 0047b558c8648e599153ac1289479e5e 356 SUPERFAMILY SSF56349 69 348 5.3E-52 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 NPD12_1457 0047b558c8648e599153ac1289479e5e 356 Gene3D G3DSA:1.10.150.130 62 154 4.9E-7 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SMART SM00387 456 568 8.8E-38 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Pfam PF00672 HAMP domain 180 225 4.2E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Gene3D G3DSA:3.30.450.20 239 339 2.2E-14 T 12-10-2018 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SMART SM00304 178 230 2.0E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SUPERFAMILY SSF55785 231 319 1.86E-8 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Gene3D G3DSA:1.10.287.130 340 415 4.6E-25 T 12-10-2018 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 234 345 2.0E-7 T 12-10-2018 IPR000014 PAS domain NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Pfam PF16736 Single Cache-like 30 134 3.1E-7 T 12-10-2018 IPR031967 PhoR, single Cache-like domain NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 507 1.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 546 1.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 565 1.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 521 1.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SUPERFAMILY SSF47384 331 411 6.47E-21 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 458 567 2.3E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Pfam PF00512 His Kinase A (phospho-acceptor) domain 346 410 3.9E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SMART SM00388 346 411 4.4E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SUPERFAMILY SSF55874 400 566 3.14E-47 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SUPERFAMILY SSF158472 180 227 5.1E-10 T 12-10-2018 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Gene3D G3DSA:1.20.1480.50 141 236 3.8E-11 T 12-10-2018 NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 SMART SM00091 237 302 6.5E-6 T 12-10-2018 IPR000014 PAS domain NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Gene3D G3DSA:3.30.565.10 416 568 5.4E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2574 09ad27f033b170ca44fe1205a664ef0d 569 Pfam PF13188 PAS domain 238 288 8.7E-6 T 12-10-2018 IPR000014 PAS domain NPD12_2742 c96b651eb4c19bfbf70eaf32f7ec3930 282 SUPERFAMILY SSF58104 115 279 6.28E-46 T 12-10-2018 NPD12_2742 c96b651eb4c19bfbf70eaf32f7ec3930 282 Gene3D G3DSA:1.10.287.950 102 282 2.8E-42 T 12-10-2018 NPD12_2742 c96b651eb4c19bfbf70eaf32f7ec3930 282 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 138 273 1.2E-30 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2742 c96b651eb4c19bfbf70eaf32f7ec3930 282 SMART SM00283 93 282 2.4E-14 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_3579 10224945b8357ecc244713f1badfdacd 176 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 171 2.8E-35 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 NPD12_3579 10224945b8357ecc244713f1badfdacd 176 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 6 175 7.7E-26 T 12-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 NPD12_3579 10224945b8357ecc244713f1badfdacd 176 Gene3D G3DSA:3.40.920.10 1 176 2.4E-56 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 NPD12_3579 10224945b8357ecc244713f1badfdacd 176 SUPERFAMILY SSF53323 4 176 3.53E-42 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 NPD12_381 33195955025df10636ec8aa1047ab275 241 Gene3D G3DSA:3.20.20.370 19 234 9.4E-64 T 12-10-2018 NPD12_381 33195955025df10636ec8aa1047ab275 241 SUPERFAMILY SSF88713 37 232 1.27E-53 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_381 33195955025df10636ec8aa1047ab275 241 Pfam PF01522 Polysaccharide deacetylase 35 143 5.2E-32 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 NPD12_3351 b20293e9caa1770b749c9767408d780c 146 Gene3D G3DSA:2.30.30.20 94 146 6.5E-15 T 12-10-2018 NPD12_3351 b20293e9caa1770b749c9767408d780c 146 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 4 92 1.0E-26 T 12-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal NPD12_3351 b20293e9caa1770b749c9767408d780c 146 SUPERFAMILY SSF54893 1 93 8.89E-32 T 12-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily NPD12_3351 b20293e9caa1770b749c9767408d780c 146 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 95 142 6.3E-16 T 12-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal NPD12_3351 b20293e9caa1770b749c9767408d780c 146 SUPERFAMILY SSF57825 95 143 7.72E-16 T 12-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily NPD12_3351 b20293e9caa1770b749c9767408d780c 146 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 2 90 4.9E-29 T 12-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal NPD12_3351 b20293e9caa1770b749c9767408d780c 146 Gene3D G3DSA:3.30.70.140 1 93 7.0E-29 T 12-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily NPD12_3351 b20293e9caa1770b749c9767408d780c 146 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 145 27.525 T 12-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 NPD12_3404 ee1b455511d05391a40d30ddfca06fb6 667 Pfam PF07495 Y_Y_Y domain 412 469 2.3E-8 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3404 ee1b455511d05391a40d30ddfca06fb6 667 Pfam PF07495 Y_Y_Y domain 508 572 8.2E-10 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3404 ee1b455511d05391a40d30ddfca06fb6 667 Pfam PF07495 Y_Y_Y domain 217 284 5.7E-12 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3404 ee1b455511d05391a40d30ddfca06fb6 667 Pfam PF07495 Y_Y_Y domain 27 91 3.6E-10 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3404 ee1b455511d05391a40d30ddfca06fb6 667 Pfam PF07495 Y_Y_Y domain 313 377 2.4E-8 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3404 ee1b455511d05391a40d30ddfca06fb6 667 Pfam PF07495 Y_Y_Y domain 126 185 1.5E-6 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_2465 231d5d8f007b2cb80f3ee6c88a133b03 120 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 91 1.0E-31 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 NPD12_2465 231d5d8f007b2cb80f3ee6c88a133b03 120 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 4 109 26.472 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 NPD12_2465 231d5d8f007b2cb80f3ee6c88a133b03 120 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 NPD12_2465 231d5d8f007b2cb80f3ee6c88a133b03 120 SUPERFAMILY SSF89919 2 112 1.7E-34 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily NPD12_2465 231d5d8f007b2cb80f3ee6c88a133b03 120 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 114 7.9E-35 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 NPD12_2465 231d5d8f007b2cb80f3ee6c88a133b03 120 Gene3D G3DSA:3.30.300.20 1 118 3.2E-38 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_2465 231d5d8f007b2cb80f3ee6c88a133b03 120 Pfam PF02033 Ribosome-binding factor A 5 109 6.6E-32 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 NPD12_3415 42c594ccf4b3381957014f5f8d0c3755 264 SMART SM00893 22 216 5.0E-66 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3415 42c594ccf4b3381957014f5f8d0c3755 264 Pfam PF01012 Electron transfer flavoprotein domain 23 211 1.8E-49 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3415 42c594ccf4b3381957014f5f8d0c3755 264 Gene3D G3DSA:3.40.50.620 1 262 8.5E-98 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3415 42c594ccf4b3381957014f5f8d0c3755 264 PIRSF PIRSF000090 1 264 5.3E-94 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 NPD12_3415 42c594ccf4b3381957014f5f8d0c3755 264 SUPERFAMILY SSF52402 1 259 4.54E-82 T 12-10-2018 NPD12_171 167bc495eb946d937629e28d3507e7cb 86 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 4 86 1.9E-28 T 12-10-2018 IPR010001 SigmaK-factor processing regulatory BofA NPD12_171 167bc495eb946d937629e28d3507e7cb 86 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 85 2.5E-24 T 12-10-2018 IPR010001 SigmaK-factor processing regulatory BofA NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 SUPERFAMILY SSF58104 232 569 4.19E-59 T 12-10-2018 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 SMART SM00304 212 264 9.0E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 SMART SM00304 503 556 70.0 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 SMART SM00283 293 569 4.5E-37 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 Gene3D G3DSA:1.20.1480.50 170 266 1.3E-7 T 12-10-2018 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 Gene3D G3DSA:1.10.287.950 267 569 4.7E-60 T 12-10-2018 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 6.0E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 420 449 6.0E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 418 6.0E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 Pfam PF00672 HAMP domain 212 259 2.8E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 185 1.6E-47 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain NPD12_2856 8cc5f7e65384ff90bf1bd4c8e34a1aa1 570 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 344 520 1.7E-31 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1828 231e3d196e800db638e2e0dd0164373f 472 Pfam PF13520 Amino acid permease 13 412 1.2E-63 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_1828 231e3d196e800db638e2e0dd0164373f 472 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 3 472 3.3E-135 T 12-10-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 NPD12_1828 231e3d196e800db638e2e0dd0164373f 472 Gene3D G3DSA:1.20.1740.10 1 469 1.5E-64 T 12-10-2018 NPD12_1828 231e3d196e800db638e2e0dd0164373f 472 PIRSF PIRSF006060 1 472 2.5E-54 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_72 6b1ac9e98eedb14c1989b5eb17bd7caf 74 SUPERFAMILY SSF47336 2 73 3.01E-18 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_72 6b1ac9e98eedb14c1989b5eb17bd7caf 74 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 71 4.0E-22 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 NPD12_72 6b1ac9e98eedb14c1989b5eb17bd7caf 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 72 2.0E-8 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 NPD12_72 6b1ac9e98eedb14c1989b5eb17bd7caf 74 Hamap MF_01217 Acyl carrier protein [acpP]. 1 72 18.322 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 NPD12_72 6b1ac9e98eedb14c1989b5eb17bd7caf 74 Pfam PF00550 Phosphopantetheine attachment site 4 68 1.1E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain NPD12_72 6b1ac9e98eedb14c1989b5eb17bd7caf 74 Gene3D G3DSA:1.10.1200.10 1 74 3.5E-21 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Pfam PF01584 CheW-like domain 566 690 2.7E-25 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 319 378 6.0E-16 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Gene3D G3DSA:2.30.30.40 562 687 6.2E-35 T 12-10-2018 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SUPERFAMILY SSF55052 169 252 6.8E-25 T 12-10-2018 IPR035891 CheY-binding domain of CheA NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SMART SM00073 3 100 9.5E-32 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SMART SM00260 554 691 7.9E-34 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 482 1.4E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 559 1.4E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 540 1.4E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Gene3D G3DSA:1.20.120.160 1 145 2.3E-40 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Gene3D G3DSA:3.30.70.1110 169 253 3.4E-29 T 12-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SUPERFAMILY SSF55874 381 560 3.8E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Pfam PF01627 Hpt domain 6 100 3.4E-20 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Gene3D G3DSA:3.30.565.10 379 561 4.0E-53 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SUPERFAMILY SSF47384 319 379 9.42E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Gene3D G3DSA:1.10.287.560 318 378 1.3E-21 T 12-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SMART SM00387 423 562 2.8E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Gene3D G3DSA:2.40.50.180 585 646 6.2E-35 T 12-10-2018 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SUPERFAMILY SSF47226 3 125 9.42E-33 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 561 6.4E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 Pfam PF07194 P2 response regulator binding domain 172 250 2.6E-26 T 12-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SUPERFAMILY SSF50341 561 691 4.58E-30 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 NPD12_2781 55b96e1ad284526f083a47bd7fc467c9 691 SMART SM01231 318 378 1.3E-19 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 NPD12_1615 c518a6d5696d4cf4691479a6c19e93c0 213 PIRSF PIRSF020269 1 213 1.2E-87 T 12-10-2018 IPR009501 Uncharacterised conserved protein UCP020269 NPD12_1615 c518a6d5696d4cf4691479a6c19e93c0 213 Pfam PF02589 LUD domain 13 207 2.7E-58 T 12-10-2018 IPR003741 LUD domain NPD12_1615 c518a6d5696d4cf4691479a6c19e93c0 213 SUPERFAMILY SSF100950 11 154 5.86E-5 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 SMART SM00091 411 477 0.0037 T 12-10-2018 IPR000014 PAS domain NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 SUPERFAMILY SSF55785 409 490 4.57E-7 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 SUPERFAMILY SSF54862 10 73 5.15E-17 T 12-10-2018 NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 Gene3D G3DSA:3.40.950.20 101 332 8.3E-24 T 12-10-2018 NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 SUPERFAMILY SSF53920 39 322 2.22E-55 T 12-10-2018 IPR009016 Iron hydrogenase NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 Gene3D G3DSA:1.10.15.40 357 414 3.0E-5 T 12-10-2018 NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 Pfam PF12838 4Fe-4S dicluster domain 11 54 7.1E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 Gene3D G3DSA:3.30.70.20 5 62 1.2E-12 T 12-10-2018 NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 Gene3D G3DSA:3.30.450.20 415 518 2.4E-8 T 12-10-2018 NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 83 299 5.7E-51 T 12-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal NPD12_1980 4dafc76390a2bee78edf5854de141a76 574 Pfam PF04060 Putative Fe-S cluster 374 402 6.5E-7 T 12-10-2018 IPR007202 4Fe-4S domain GO:0051536 NPD12_641 154f3d2084e0d54136fdecce2ccc6435 283 Gene3D G3DSA:3.30.70.120 193 268 1.4E-20 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal NPD12_641 154f3d2084e0d54136fdecce2ccc6435 283 PIRSF PIRSF006483 1 283 2.0E-85 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT NPD12_641 154f3d2084e0d54136fdecce2ccc6435 283 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 215 3.8E-57 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT NPD12_641 154f3d2084e0d54136fdecce2ccc6435 283 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 275 1.4E-17 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 NPD12_2421 8516f15a597c64bce0d9e7010c2370a9 457 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 223 2.1E-10 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like NPD12_2318 2925a56015124d721637cc8825b743b5 410 Gene3D G3DSA:3.40.50.11900 296 407 3.5E-5 T 12-10-2018 NPD12_2318 2925a56015124d721637cc8825b743b5 410 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 41 400 3.0E-72 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_2318 2925a56015124d721637cc8825b743b5 410 Gene3D G3DSA:3.40.50.11890 33 177 1.4E-9 T 12-10-2018 NPD12_2318 2925a56015124d721637cc8825b743b5 410 Gene3D G3DSA:1.20.1270.370 21 197 1.4E-9 T 12-10-2018 NPD12_2317 c5053fb9847303034d33a4d011762775 375 Gene3D G3DSA:1.20.1270.370 13 220 2.9E-82 T 12-10-2018 NPD12_2317 c5053fb9847303034d33a4d011762775 375 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 39 375 1.4E-61 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_2317 c5053fb9847303034d33a4d011762775 375 Gene3D G3DSA:3.40.50.11900 233 375 6.8E-51 T 12-10-2018 NPD12_2317 c5053fb9847303034d33a4d011762775 375 Gene3D G3DSA:3.40.50.11890 31 156 2.9E-82 T 12-10-2018 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 Gene3D G3DSA:3.40.630.10 2 286 3.9E-62 T 12-10-2018 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 SUPERFAMILY SSF53187 11 480 8.38E-59 T 12-10-2018 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 Pfam PF07687 Peptidase dimerisation domain 211 290 1.6E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 SUPERFAMILY SSF55031 204 300 5.38E-5 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 Pfam PF01546 Peptidase family M20/M25/M40 73 479 5.3E-21 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 249 268 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 426 442 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 361 379 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 204 221 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PRINTS PR00934 X-His dipeptidase (M25) signature 448 470 5.3E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 7 481 2.5E-183 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 Gene3D G3DSA:3.40.630.10 347 481 2.8E-23 T 12-10-2018 NPD12_2355 46549d709551a4cc2f0a4c814fc0f487 481 PIRSF PIRSF016599 1 481 1.8E-188 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2274 a268d5a57df7060a0a8cc266ac7da4f9 719 SUPERFAMILY SSF55486 483 710 8.79E-15 T 12-10-2018 NPD12_2274 a268d5a57df7060a0a8cc266ac7da4f9 719 Gene3D G3DSA:1.10.390.60 474 718 2.1E-21 T 12-10-2018 NPD12_2274 a268d5a57df7060a0a8cc266ac7da4f9 719 Pfam PF01433 Peptidase family M1 domain 553 709 5.1E-8 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 NPD12_1846 01c8cf542cbb96a80b0c1c58102b5e28 552 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 5 551 7.0E-282 T 12-10-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199 NPD12_1846 01c8cf542cbb96a80b0c1c58102b5e28 552 Gene3D G3DSA:3.30.1360.60 473 552 8.6E-25 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1846 01c8cf542cbb96a80b0c1c58102b5e28 552 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 440 536 5.5E-15 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 NPD12_1846 01c8cf542cbb96a80b0c1c58102b5e28 552 SUPERFAMILY SSF55604 478 550 2.48E-17 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1846 01c8cf542cbb96a80b0c1c58102b5e28 552 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 489 506 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_1846 01c8cf542cbb96a80b0c1c58102b5e28 552 Pfam PF02378 Phosphotransferase system, EIIC 16 379 6.8E-54 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_1846 01c8cf542cbb96a80b0c1c58102b5e28 552 Pfam PF00367 phosphotransferase system, EIIB 479 510 6.7E-13 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_1803 3b25338d0f117e1429938aac10d98b53 212 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 211 3.1E-90 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 NPD12_1803 3b25338d0f117e1429938aac10d98b53 212 Pfam PF01791 DeoC/LacD family aldolase 5 207 5.9E-23 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 NPD12_1803 3b25338d0f117e1429938aac10d98b53 212 Gene3D G3DSA:3.20.20.70 1 212 3.4E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1803 3b25338d0f117e1429938aac10d98b53 212 SMART SM01133 2 212 2.6E-99 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 NPD12_1803 3b25338d0f117e1429938aac10d98b53 212 SUPERFAMILY SSF51569 1 211 6.28E-85 T 12-10-2018 NPD12_1803 3b25338d0f117e1429938aac10d98b53 212 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 212 35.875 T 12-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 NPD12_1803 3b25338d0f117e1429938aac10d98b53 212 PIRSF PIRSF001357 1 212 1.1E-78 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 NPD12_475 d3e74df3de6e6ff78ecc873f8db9b1cf 342 SUPERFAMILY SSF81345 14 334 2.75E-79 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_475 d3e74df3de6e6ff78ecc873f8db9b1cf 342 Gene3D G3DSA:1.10.3470.10 14 341 2.0E-92 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_475 d3e74df3de6e6ff78ecc873f8db9b1cf 342 Pfam PF01032 FecCD transport family 26 335 2.5E-91 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 SUPERFAMILY SSF52540 5 249 5.92E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 309 6.9E-13 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 290 7.9E-10 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 Pfam PF00005 ABC transporter 339 485 3.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 Gene3D G3DSA:3.40.50.300 2 312 1.5E-79 T 12-10-2018 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 Gene3D G3DSA:3.40.50.300 313 560 8.3E-69 T 12-10-2018 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 SMART SM00382 32 230 8.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 SMART SM00382 345 536 3.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 ProSitePatterns PS00211 ABC transporters family signature. 459 473 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 Pfam PF00005 ABC transporter 23 179 1.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 SUPERFAMILY SSF52540 316 557 5.43E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1913 1df330bc3c9b35fb9a5c357cc515d08e 560 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_133 f125d41222df129a928130f4714cc189 637 Gene3D G3DSA:3.30.230.10 222 400 1.0E-72 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_133 f125d41222df129a928130f4714cc189 637 Pfam PF00204 DNA gyrase B 223 392 3.0E-61 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_133 f125d41222df129a928130f4714cc189 637 SMART SM00387 34 178 5.0E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_133 f125d41222df129a928130f4714cc189 637 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 177 7.5E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_133 f125d41222df129a928130f4714cc189 637 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 9 637 0.0 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 565 626 8.3E-32 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 Gene3D G3DSA:3.40.50.670 401 637 1.6E-111 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_133 f125d41222df129a928130f4714cc189 637 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 6 637 94.431 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 Gene3D G3DSA:3.30.565.10 5 221 7.0E-93 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 506 523 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 526 538 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 38 53 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 569 585 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 422 436 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 116 130 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 73 86 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 488 504 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR00418 DNA topoisomerase II family signature 270 283 3.7E-73 T 12-10-2018 NPD12_133 f125d41222df129a928130f4714cc189 637 SUPERFAMILY SSF55874 9 220 1.44E-76 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_133 f125d41222df129a928130f4714cc189 637 SUPERFAMILY SSF54211 223 393 4.36E-60 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_133 f125d41222df129a928130f4714cc189 637 SUPERFAMILY SSF56719 396 631 2.07E-93 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 NPD12_133 f125d41222df129a928130f4714cc189 637 SMART SM00433 38 630 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_133 f125d41222df129a928130f4714cc189 637 ProSitePatterns PS00177 DNA topoisomerase II signature. 424 432 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 472 481 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 198 211 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 362 376 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 183 198 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 314 330 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 9 19 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 590 602 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 222 244 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 376 396 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 PRINTS PR01159 DNA gyrase subunit B signature 606 622 8.9E-79 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 NPD12_133 f125d41222df129a928130f4714cc189 637 Pfam PF01751 Toprim domain 421 532 8.5E-18 T 12-10-2018 IPR006171 TOPRIM domain NPD12_269 960cf369163c4da00966ab1ccb603fde 334 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 13 326 7.0E-111 T 12-10-2018 IPR014255 Spore coat protein CotS NPD12_269 960cf369163c4da00966ab1ccb603fde 334 SUPERFAMILY SSF56112 9 329 1.68E-53 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_269 960cf369163c4da00966ab1ccb603fde 334 Pfam PF01633 Choline/ethanolamine kinase 88 243 2.2E-12 T 12-10-2018 NPD12_269 960cf369163c4da00966ab1ccb603fde 334 Gene3D G3DSA:3.90.1200.10 91 325 2.4E-73 T 12-10-2018 NPD12_269 960cf369163c4da00966ab1ccb603fde 334 Gene3D G3DSA:3.30.200.20 1 90 2.4E-18 T 12-10-2018 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 Gene3D G3DSA:1.10.287.130 238 311 1.7E-21 T 12-10-2018 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 306 6.0E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 Gene3D G3DSA:3.30.450.20 34 167 3.9E-5 T 12-10-2018 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 Gene3D G3DSA:3.30.565.10 312 463 1.1E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 SUPERFAMILY SSF47384 226 310 9.22E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 SUPERFAMILY SSF103190 73 156 4.71E-5 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 Pfam PF00672 HAMP domain 191 238 5.8E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 SMART SM00388 243 309 1.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 6.7E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 6.7E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 6.7E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 SUPERFAMILY SSF158472 191 238 5.89E-9 T 12-10-2018 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 SUPERFAMILY SSF55874 299 461 1.83E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 461 1.4E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 SMART SM00304 190 242 2.0E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 SMART SM00387 355 463 1.0E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_517 fbbbf56966530cf5bd21add2c4b6959c 464 Gene3D G3DSA:1.10.8.500 189 237 3.5E-8 T 12-10-2018 NPD12_3709 462a4695abf7c2e85401931f848cf60f 134 Gene3D G3DSA:2.40.50.140 2 83 1.1E-28 T 12-10-2018 NPD12_3709 462a4695abf7c2e85401931f848cf60f 134 SUPERFAMILY SSF50249 4 82 1.93E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3709 462a4695abf7c2e85401931f848cf60f 134 Pfam PF00575 S1 RNA binding domain 3 73 6.2E-20 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_3709 462a4695abf7c2e85401931f848cf60f 134 SMART SM00316 4 73 2.9E-27 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_3203 a41c6fd33306661bd54c276d81dc2830 474 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 353 429 1.2E-9 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain NPD12_3203 a41c6fd33306661bd54c276d81dc2830 474 Pfam PF01943 Polysaccharide biosynthesis protein 15 275 1.8E-19 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 NPD12_454 7c71ae6dca87df6eca6b55149457714b 526 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 460 477 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_454 7c71ae6dca87df6eca6b55149457714b 526 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 410 507 1.1E-16 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 NPD12_454 7c71ae6dca87df6eca6b55149457714b 526 Pfam PF00367 phosphotransferase system, EIIB 451 482 7.6E-14 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_454 7c71ae6dca87df6eca6b55149457714b 526 Gene3D G3DSA:3.30.1360.60 443 523 2.9E-24 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_454 7c71ae6dca87df6eca6b55149457714b 526 SUPERFAMILY SSF55604 448 522 6.15E-20 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_454 7c71ae6dca87df6eca6b55149457714b 526 Pfam PF02378 Phosphotransferase system, EIIC 13 350 1.5E-66 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_3464 fb914eb9877be4375355dc94af86f9a5 29 Gene3D G3DSA:3.30.70.1290 1 29 2.5E-5 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 NPD12_3464 fb914eb9877be4375355dc94af86f9a5 29 Pfam PF01797 Transposase IS200 like 3 28 3.0E-5 T 12-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 NPD12_3464 fb914eb9877be4375355dc94af86f9a5 29 SUPERFAMILY SSF143422 2 27 2.75E-7 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 NPD12_2754 8a3b0c4b6ce005d8f5bf998ce2307e97 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 159 191 9.6E-6 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_2754 8a3b0c4b6ce005d8f5bf998ce2307e97 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 123 157 4.3E-9 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_2754 8a3b0c4b6ce005d8f5bf998ce2307e97 212 SUPERFAMILY SSF51161 1 210 2.08E-49 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_2754 8a3b0c4b6ce005d8f5bf998ce2307e97 212 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 3 207 7.2E-68 T 12-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like NPD12_2754 8a3b0c4b6ce005d8f5bf998ce2307e97 212 Gene3D G3DSA:2.160.10.10 93 201 5.0E-32 T 12-10-2018 NPD12_2754 8a3b0c4b6ce005d8f5bf998ce2307e97 212 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 167 195 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 NPD12_2754 8a3b0c4b6ce005d8f5bf998ce2307e97 212 Gene3D G3DSA:3.40.50.20 1 91 6.1E-25 T 12-10-2018 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 152 1.7E-23 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Pfam PF00679 Elongation factor G C-terminus 400 485 3.7E-23 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Gene3D G3DSA:3.30.70.240 393 485 1.8E-131 T 12-10-2018 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 SUPERFAMILY SSF54980 306 391 7.91E-16 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_2604 b15ec1d97930047d771e7f206b409267 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site NPD12_2604 b15ec1d97930047d771e7f206b409267 608 SUPERFAMILY SSF54980 402 516 3.88E-28 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_2604 b15ec1d97930047d771e7f206b409267 608 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 9 602 5.1E-294 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Gene3D G3DSA:3.40.50.300 6 202 1.3E-68 T 12-10-2018 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Pfam PF03144 Elongation factor Tu domain 2 223 292 1.5E-9 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 SUPERFAMILY SSF50447 156 302 3.09E-30 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_2604 b15ec1d97930047d771e7f206b409267 608 PRINTS PR00315 GTP-binding elongation factor signature 75 85 4.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 PRINTS PR00315 GTP-binding elongation factor signature 55 63 4.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 PRINTS PR00315 GTP-binding elongation factor signature 127 136 4.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 PRINTS PR00315 GTP-binding elongation factor signature 11 24 4.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Gene3D G3DSA:3.30.70.870 310 593 1.8E-131 T 12-10-2018 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 SUPERFAMILY SSF52540 5 211 5.35E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Gene3D G3DSA:2.40.50.250 486 602 1.8E-131 T 12-10-2018 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Gene3D G3DSA:2.40.30.10 204 303 1.5E-35 T 12-10-2018 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 Pfam PF00009 Elongation factor Tu GTP binding domain 8 199 3.8E-54 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2604 b15ec1d97930047d771e7f206b409267 608 SMART SM00838 401 487 6.4E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_595 66d0ed9ce2a66722d70b66281578e1d9 275 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 264 44.431 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 NPD12_595 66d0ed9ce2a66722d70b66281578e1d9 275 Gene3D G3DSA:3.20.20.60 2 274 1.2E-119 T 12-10-2018 NPD12_595 66d0ed9ce2a66722d70b66281578e1d9 275 SUPERFAMILY SSF51621 3 264 2.0E-110 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 NPD12_595 66d0ed9ce2a66722d70b66281578e1d9 275 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 260 3.4E-119 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 NPD12_595 66d0ed9ce2a66722d70b66281578e1d9 275 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 4 265 9.0E-108 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 NPD12_595 66d0ed9ce2a66722d70b66281578e1d9 275 PIRSF PIRSF000388 1 267 3.1E-115 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 91 262 1.1E-19 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 Gene3D G3DSA:3.40.50.300 59 276 9.3E-32 T 12-10-2018 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 345 533 2.7E-34 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 532 1.4E-273 T 12-10-2018 IPR014251 Sporulation protease LonB NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 SUPERFAMILY SSF54211 348 531 6.45E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 171 186 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 SMART SM00382 87 265 2.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 SUPERFAMILY SSF52540 52 326 3.79E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 Gene3D G3DSA:3.30.230.10 345 551 3.6E-52 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 1.5E-31 T 12-10-2018 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 1.5E-31 T 12-10-2018 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 1.5E-31 T 12-10-2018 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 95 114 1.5E-31 T 12-10-2018 NPD12_3340 482e73e2506afd79579a6281ad6dc248 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 350 366 1.5E-31 T 12-10-2018 NPD12_2240 db4294df53e3e04adf83b183ac0c3fba 96 Gene3D G3DSA:3.30.70.1710 1 96 1.6E-40 T 12-10-2018 NPD12_2240 db4294df53e3e04adf83b183ac0c3fba 96 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 22 41 - T 12-10-2018 IPR020808 Bacterial microcompartments protein, conserved site NPD12_2240 db4294df53e3e04adf83b183ac0c3fba 96 SUPERFAMILY SSF143414 3 91 4.32E-32 T 12-10-2018 IPR037233 CcmK-like superfamily NPD12_2240 db4294df53e3e04adf83b183ac0c3fba 96 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 48 3.0E-17 T 12-10-2018 NPD12_2240 db4294df53e3e04adf83b183ac0c3fba 96 Pfam PF00936 BMC domain 5 80 8.5E-28 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2240 db4294df53e3e04adf83b183ac0c3fba 96 SMART SM00877 4 80 1.3E-35 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 Pfam PF02780 Transketolase, C-terminal domain 491 612 1.5E-30 T 12-10-2018 IPR033248 Transketolase, C-terminal domain NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 SUPERFAMILY SSF52518 4 346 3.93E-79 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 SUPERFAMILY SSF52922 489 619 4.06E-32 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 Pfam PF02779 Transketolase, pyrimidine binding domain 315 474 4.3E-38 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 ProSitePatterns PS00801 Transketolase signature 1. 30 49 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 280 9.2E-122 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 SMART SM00861 315 479 9.0E-66 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 9 619 2.8E-253 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 Gene3D G3DSA:3.40.50.970 313 487 1.1E-67 T 12-10-2018 NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 4 620 44.549 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 SUPERFAMILY SSF52518 289 475 2.78E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_2047 854c0e10bb8b0711d24ce4b33d06b720 620 Gene3D G3DSA:3.40.50.920 491 620 2.0E-36 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_1535 4b12c1e40127f9405a62a5561a92e7da 292 SMART SM01092 181 283 6.3E-20 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal NPD12_1535 4b12c1e40127f9405a62a5561a92e7da 292 Gene3D G3DSA:3.30.465.10 4 175 1.8E-52 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 NPD12_1535 4b12c1e40127f9405a62a5561a92e7da 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 282 7.0E-16 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal NPD12_1535 4b12c1e40127f9405a62a5561a92e7da 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 7 171 3.3E-45 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 NPD12_1535 4b12c1e40127f9405a62a5561a92e7da 292 Gene3D G3DSA:3.30.390.50 180 285 3.8E-23 T 12-10-2018 NPD12_1535 4b12c1e40127f9405a62a5561a92e7da 292 SUPERFAMILY SSF55447 180 282 1.83E-19 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily NPD12_1535 4b12c1e40127f9405a62a5561a92e7da 292 SUPERFAMILY SSF56176 7 171 3.18E-45 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_273 5bf482cfeb66718d6799e60867fb550d 266 SUPERFAMILY SSF52317 9 223 3.05E-23 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_273 5bf482cfeb66718d6799e60867fb550d 266 PIRSF PIRSF032067 2 264 4.6E-65 T 12-10-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 NPD12_273 5bf482cfeb66718d6799e60867fb550d 266 Gene3D G3DSA:3.40.50.880 4 265 3.5E-76 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_273 5bf482cfeb66718d6799e60867fb550d 266 TIGRFAM TIGR02069 cyanophycinase: cyanophycinase 9 258 1.2E-106 T 12-10-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 NPD12_273 5bf482cfeb66718d6799e60867fb550d 266 Pfam PF03575 Peptidase family S51 9 209 6.8E-24 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 NPD12_2233 5c1bdc4a5a0a3ad3de9fccf8b5adb8dd 107 SUPERFAMILY SSF46785 15 104 1.49E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2233 5c1bdc4a5a0a3ad3de9fccf8b5adb8dd 107 Gene3D G3DSA:1.10.10.10 3 106 4.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2233 5c1bdc4a5a0a3ad3de9fccf8b5adb8dd 107 Pfam PF03551 Transcriptional regulator PadR-like family 20 83 7.4E-12 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 SUPERFAMILY SSF53335 188 344 8.74E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 1.3E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 1.3E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 1.3E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 Pfam PF13411 MerR HTH family regulatory protein 9 76 1.4E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 SMART SM00422 9 78 1.3E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 Gene3D G3DSA:3.40.50.150 193 378 2.5E-34 T 12-10-2018 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 Pfam PF08241 Methyltransferase domain 214 311 8.6E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 SUPERFAMILY SSF46955 9 129 9.89E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_1018 19b6267f74cf45eb8d1d93e6f161f33a 429 Gene3D G3DSA:1.10.1660.10 7 148 2.9E-32 T 12-10-2018 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 Gene3D G3DSA:3.30.1490.110 88 179 9.2E-40 T 12-10-2018 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 SUPERFAMILY SSF53067 13 206 1.6E-24 T 12-10-2018 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 Gene3D G3DSA:3.30.420.40 207 352 9.2E-40 T 12-10-2018 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 SUPERFAMILY SSF53067 215 382 1.3E-26 T 12-10-2018 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 Gene3D G3DSA:3.30.420.40 15 355 9.2E-40 T 12-10-2018 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 Pfam PF06723 MreB/Mbl protein 201 353 1.2E-11 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 SMART SM00842 12 206 1.3E-48 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 NPD12_1681 6a640f5b466911bf1b56dd7bf59a071f 742 Gene3D G3DSA:3.90.640.10 245 301 9.2E-40 T 12-10-2018 NPD12_113 00b345edec576f5d791ac960406dff5f 351 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 351 2.9E-86 T 12-10-2018 IPR014227 Putative transport protein YtvI-like NPD12_113 00b345edec576f5d791ac960406dff5f 351 Pfam PF01594 AI-2E family transporter 12 342 6.8E-44 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like NPD12_867 b6f3150590022ba24ffe90ab3b152646 422 SUPERFAMILY SSF53807 16 412 1.77E-61 T 12-10-2018 NPD12_867 b6f3150590022ba24ffe90ab3b152646 422 Gene3D G3DSA:3.40.50.12380 166 418 4.2E-11 T 12-10-2018 NPD12_867 b6f3150590022ba24ffe90ab3b152646 422 Gene3D G3DSA:3.40.50.1980 22 165 4.4E-23 T 12-10-2018 NPD12_867 b6f3150590022ba24ffe90ab3b152646 422 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 32 413 1.7E-65 T 12-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 Pfam PF01842 ACT domain 345 408 6.4E-12 T 12-10-2018 IPR002912 ACT domain NPD12_1880 342d5514dae1705beec3baaff89eca21 425 Pfam PF00742 Homoserine dehydrogenase 137 315 5.1E-67 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 Gene3D G3DSA:3.30.70.260 340 412 1.7E-160 T 12-10-2018 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 SUPERFAMILY SSF55021 344 416 3.49E-15 T 12-10-2018 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 Gene3D G3DSA:3.40.50.720 4 331 1.7E-160 T 12-10-2018 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 SUPERFAMILY SSF51735 3 158 5.05E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1880 342d5514dae1705beec3baaff89eca21 425 SUPERFAMILY SSF55347 137 302 3.2E-55 T 12-10-2018 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 PIRSF PIRSF000098 1 424 1.5E-167 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 Gene3D G3DSA:3.30.360.10 136 339 1.7E-160 T 12-10-2018 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 4.4E-19 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 NPD12_1880 342d5514dae1705beec3baaff89eca21 425 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 NPD12_1298 a4025005e003866007d54fab1c7f5251 181 Gene3D G3DSA:1.25.40.10 32 177 5.0E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1298 a4025005e003866007d54fab1c7f5251 181 Pfam PF13181 Tetratricopeptide repeat 40 68 4.1E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1298 a4025005e003866007d54fab1c7f5251 181 SUPERFAMILY SSF48452 41 178 4.43E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1819 6bce5bc7af0fef8b6dcc0a8586016f1e 416 PRINTS PR00175 Sodium/alanine symporter signature 188 207 4.8E-6 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1819 6bce5bc7af0fef8b6dcc0a8586016f1e 416 PRINTS PR00175 Sodium/alanine symporter signature 385 405 4.8E-6 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1819 6bce5bc7af0fef8b6dcc0a8586016f1e 416 PRINTS PR00175 Sodium/alanine symporter signature 328 350 4.8E-6 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1819 6bce5bc7af0fef8b6dcc0a8586016f1e 416 PRINTS PR00175 Sodium/alanine symporter signature 68 90 4.8E-6 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1819 6bce5bc7af0fef8b6dcc0a8586016f1e 416 Pfam PF01235 Sodium:alanine symporter family 37 406 2.2E-25 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_3157 64add5207a928597968a279e23abbe44 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 66 4.2E-25 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 NPD12_3157 64add5207a928597968a279e23abbe44 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 45 59 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 NPD12_3157 64add5207a928597968a279e23abbe44 67 Gene3D G3DSA:1.10.8.910 7 67 4.2E-23 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily NPD12_3157 64add5207a928597968a279e23abbe44 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 NPD12_1523 df97e9ac31c1b3b025912f00727aa582 291 SUPERFAMILY SSF161111 8 208 7.85E-57 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily NPD12_1523 df97e9ac31c1b3b025912f00727aa582 291 Gene3D G3DSA:3.30.70.1350 208 290 2.2E-15 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 NPD12_1523 df97e9ac31c1b3b025912f00727aa582 291 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 289 2.7E-21 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain NPD12_1523 df97e9ac31c1b3b025912f00727aa582 291 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 290 1.8E-77 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 NPD12_1523 df97e9ac31c1b3b025912f00727aa582 291 SUPERFAMILY SSF160240 211 290 2.75E-17 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 NPD12_1523 df97e9ac31c1b3b025912f00727aa582 291 Pfam PF01545 Cation efflux family 17 207 1.2E-51 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 NPD12_1523 df97e9ac31c1b3b025912f00727aa582 291 Gene3D G3DSA:1.20.1510.10 11 207 9.4E-65 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 SUPERFAMILY SSF52540 3 187 8.5E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 Hamap MF_00328 Guanylate kinase [gmk]. 3 185 36.318 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 182 6.6E-73 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 Pfam PF00625 Guanylate kinase 7 183 2.1E-48 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 Gene3D G3DSA:3.40.50.300 9 181 3.2E-66 T 12-10-2018 NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 ProSitePatterns PS00856 Guanylate kinase-like signature. 38 55 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 SMART SM00072 4 185 3.7E-61 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit NPD12_2561 0140e2805bae88e59a9377d364b74f9f 209 Gene3D G3DSA:3.30.63.10 35 94 3.2E-66 T 12-10-2018 NPD12_1121 c2d65ab82c95845cb19e7bb561499cc1 359 PIRSF PIRSF026782 9 359 2.0E-122 T 12-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 NPD12_1121 c2d65ab82c95845cb19e7bb561499cc1 359 Pfam PF01888 CbiD 13 267 9.1E-96 T 12-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 NPD12_1121 c2d65ab82c95845cb19e7bb561499cc1 359 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 13 357 29.044 T 12-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 NPD12_1121 c2d65ab82c95845cb19e7bb561499cc1 359 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 20 358 1.4E-86 T 12-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 NPD12_1121 c2d65ab82c95845cb19e7bb561499cc1 359 SUPERFAMILY SSF111342 3 284 9.02E-87 T 12-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 NPD12_1121 c2d65ab82c95845cb19e7bb561499cc1 359 Gene3D G3DSA:3.30.2110.10 15 183 1.7E-52 T 12-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 NPD12_486 e626d0a784aac51cff391a9f40b2887f 620 PIRSF PIRSF018968 1 616 3.3E-123 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 NPD12_486 e626d0a784aac51cff391a9f40b2887f 620 Pfam PF02687 FtsX-like permease family 85 174 1.8E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_209 d32f91634bd1be495a549de7eea29e6a 386 Gene3D G3DSA:3.30.70.360 162 278 4.9E-86 T 12-10-2018 NPD12_209 d32f91634bd1be495a549de7eea29e6a 386 Gene3D G3DSA:3.40.630.10 18 357 4.9E-86 T 12-10-2018 NPD12_209 d32f91634bd1be495a549de7eea29e6a 386 SUPERFAMILY SSF53187 3 370 3.24E-43 T 12-10-2018 NPD12_209 d32f91634bd1be495a549de7eea29e6a 386 PIRSF PIRSF037226 1 386 1.2E-94 T 12-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted NPD12_497 3a7b13961b111a9953de96362a1bd688 567 SMART SM00471 389 524 5.0E-8 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_497 3a7b13961b111a9953de96362a1bd688 567 Gene3D G3DSA:1.10.3210.10 375 563 5.6E-67 T 12-10-2018 NPD12_497 3a7b13961b111a9953de96362a1bd688 567 Pfam PF00990 Diguanylate cyclase, GGDEF domain 195 352 1.7E-47 T 12-10-2018 IPR000160 GGDEF domain NPD12_497 3a7b13961b111a9953de96362a1bd688 567 SUPERFAMILY SSF109604 379 553 1.76E-37 T 12-10-2018 NPD12_497 3a7b13961b111a9953de96362a1bd688 567 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 190 356 1.0E-55 T 12-10-2018 IPR000160 GGDEF domain NPD12_497 3a7b13961b111a9953de96362a1bd688 567 SUPERFAMILY SSF55073 199 358 3.06E-47 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_497 3a7b13961b111a9953de96362a1bd688 567 Pfam PF01966 HD domain 393 515 4.7E-19 T 12-10-2018 IPR006674 HD domain NPD12_497 3a7b13961b111a9953de96362a1bd688 567 Gene3D G3DSA:3.30.70.270 182 359 3.1E-54 T 12-10-2018 NPD12_497 3a7b13961b111a9953de96362a1bd688 567 SMART SM00267 183 357 1.5E-58 T 12-10-2018 IPR000160 GGDEF domain NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 Gene3D G3DSA:3.90.190.20 332 483 3.4E-60 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 SUPERFAMILY SSF53623 101 324 1.57E-71 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 Gene3D G3DSA:3.40.1390.10 1 100 2.7E-27 T 12-10-2018 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 SUPERFAMILY SSF53244 327 482 2.22E-46 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 327 414 4.1E-21 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 Pfam PF08245 Mur ligase middle domain 110 306 6.4E-53 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 SUPERFAMILY SSF63418 1 101 2.35E-22 T 12-10-2018 IPR035911 MurE/MurF, N-terminal NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 480 35.236 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 20 480 4.4E-165 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 Gene3D G3DSA:3.40.1190.10 101 331 1.3E-84 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_1707 347ea475a7ea31202b243f6c463f2751 483 Pfam PF01225 Mur ligase family, catalytic domain 22 98 1.4E-13 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 NPD12_510 ffaebe25339d146e8fa66a58ffa31dbd 95 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 2 90 2.9E-17 T 12-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 NPD12_510 ffaebe25339d146e8fa66a58ffa31dbd 95 PIRSF PIRSF020408 1 95 9.2E-33 T 12-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 39 377 2.3E-48 T 12-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 SUPERFAMILY SSF51445 39 381 2.9E-69 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 Gene3D G3DSA:3.20.20.80 37 381 3.1E-109 T 12-10-2018 NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 Gene3D G3DSA:2.60.40.1180 35 440 3.1E-109 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 PRINTS PR00843 Glycosyl hydrolase family 30 signature 29 49 2.0E-6 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 PRINTS PR00843 Glycosyl hydrolase family 30 signature 65 91 2.0E-6 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 PRINTS PR00843 Glycosyl hydrolase family 30 signature 93 121 2.0E-6 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 PRINTS PR00843 Glycosyl hydrolase family 30 signature 160 177 2.0E-6 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 NPD12_1386 a8960b08829c9e0e06188162a38400f9 442 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 380 439 8.7E-12 T 12-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 SMART SM01193 7 137 3.7E-97 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 PRINTS PR00148 Enolase signature 164 177 3.8E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 PRINTS PR00148 Enolase signature 40 54 3.8E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 PRINTS PR00148 Enolase signature 314 325 3.8E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 PRINTS PR00148 Enolase signature 337 351 3.8E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 PRINTS PR00148 Enolase signature 366 383 3.8E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 PRINTS PR00148 Enolase signature 110 126 3.8E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 SMART SM01192 142 428 1.9E-227 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 428 2.4E-212 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 Gene3D G3DSA:3.30.390.10 5 130 1.2E-55 T 12-10-2018 IPR029017 Enolase-like, N-terminal NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 143 426 2.1E-136 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 Hamap MF_00318 Enolase [eno]. 5 414 45.179 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 SUPERFAMILY SSF51604 142 428 1.9E-132 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 Pfam PF03952 Enolase, N-terminal domain 7 137 1.1E-60 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 Gene3D G3DSA:3.20.20.120 133 431 6.1E-139 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 SUPERFAMILY SSF54826 6 142 2.57E-57 T 12-10-2018 NPD12_388 b22722de1756d2f3ac1a0f71303ed5ed 431 PIRSF PIRSF001400 3 428 6.8E-192 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_40 e215a886b2790109646fd1471cc8b353 159 SUPERFAMILY SSF75217 1 157 3.09E-60 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases NPD12_40 e215a886b2790109646fd1471cc8b353 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 3.4E-61 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 NPD12_40 e215a886b2790109646fd1471cc8b353 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 31.754 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 NPD12_40 e215a886b2790109646fd1471cc8b353 159 PIRSF PIRSF004505 1 159 5.1E-59 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 NPD12_40 e215a886b2790109646fd1471cc8b353 159 Gene3D G3DSA:3.40.1280.10 1 159 7.7E-67 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal NPD12_40 e215a886b2790109646fd1471cc8b353 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 6.1E-54 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 NPD12_1675 d898ade0db517b4c7cfdc0b8bec225a2 493 Gene3D G3DSA:3.20.140.10 17 480 1.4E-201 T 12-10-2018 NPD12_1675 d898ade0db517b4c7cfdc0b8bec225a2 493 PIRSF PIRSF000484 8 490 3.8E-167 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 NPD12_1675 d898ade0db517b4c7cfdc0b8bec225a2 493 SUPERFAMILY SSF54675 12 145 2.5E-48 T 12-10-2018 NPD12_1675 d898ade0db517b4c7cfdc0b8bec225a2 493 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 17 476 3.4E-167 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 NPD12_1675 d898ade0db517b4c7cfdc0b8bec225a2 493 SUPERFAMILY SSF51690 146 488 1.03E-126 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 NPD12_1675 d898ade0db517b4c7cfdc0b8bec225a2 493 Gene3D G3DSA:3.20.20.70 158 328 1.4E-201 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_934 f3b21bbdcc8fe110d54078647f9916ca 113 Gene3D G3DSA:2.30.30.40 41 112 4.9E-16 T 12-10-2018 NPD12_934 f3b21bbdcc8fe110d54078647f9916ca 113 SMART SM00287 50 113 3.8E-7 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_934 f3b21bbdcc8fe110d54078647f9916ca 113 Pfam PF08239 Bacterial SH3 domain 59 107 2.0E-13 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_2327 d58a1ea8c0faa30239ed2901407b59b5 197 Gene3D G3DSA:3.40.630.30 5 196 2.5E-34 T 12-10-2018 NPD12_2327 d58a1ea8c0faa30239ed2901407b59b5 197 SUPERFAMILY SSF55729 1 184 1.59E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2327 d58a1ea8c0faa30239ed2901407b59b5 197 Pfam PF00583 Acetyltransferase (GNAT) family 47 177 3.7E-9 T 12-10-2018 IPR000182 GNAT domain NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Pfam PF00158 Sigma-54 interaction domain 327 494 5.8E-69 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Pfam PF02954 Bacterial regulatory protein, Fis family 588 628 6.6E-15 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 351 364 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 414 429 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 SMART SM00382 347 491 2.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2103 686039919546c2a96a7a51583be37e7b 631 SUPERFAMILY SSF52540 327 557 1.83E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Gene3D G3DSA:1.10.8.60 499 565 5.8E-20 T 12-10-2018 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Gene3D G3DSA:1.10.10.60 574 629 1.1E-17 T 12-10-2018 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 SUPERFAMILY SSF55785 187 304 1.06E-8 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_2103 686039919546c2a96a7a51583be37e7b 631 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 541 550 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Gene3D G3DSA:3.30.450.20 188 312 2.0E-11 T 12-10-2018 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Pfam PF13426 PAS domain 216 306 4.4E-6 T 12-10-2018 IPR000014 PAS domain NPD12_2103 686039919546c2a96a7a51583be37e7b 631 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 611 631 3.8E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 594 611 3.8E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 SUPERFAMILY SSF46689 541 630 1.04E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Gene3D G3DSA:3.30.450.40 3 187 3.6E-55 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_2103 686039919546c2a96a7a51583be37e7b 631 Gene3D G3DSA:3.40.50.300 316 498 2.1E-64 T 12-10-2018 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 Gene3D G3DSA:3.30.930.10 7 286 2.8E-104 T 12-10-2018 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 SUPERFAMILY SSF52954 282 403 6.49E-32 T 12-10-2018 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 Gene3D G3DSA:3.30.110.30 405 478 9.5E-25 T 12-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 SUPERFAMILY SSF64586 406 478 1.84E-23 T 12-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 SUPERFAMILY SSF55681 16 279 2.24E-76 T 12-10-2018 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 411 478 2.7E-25 T 12-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 Gene3D G3DSA:3.40.50.800 287 387 1.6E-30 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 Hamap MF_01571 Proline--tRNA ligase [proS]. 11 478 44.052 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 14 478 1.1E-183 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 104 274 1.9E-19 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 Pfam PF03129 Anticodon binding domain 293 384 6.4E-21 T 12-10-2018 IPR004154 Anticodon-binding NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 SMART SM00946 411 478 5.5E-34 T 12-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 PRINTS PR01046 Prolyl-tRNA synthetase signature 69 87 2.3E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 PRINTS PR01046 Prolyl-tRNA synthetase signature 140 148 2.3E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 PRINTS PR01046 Prolyl-tRNA synthetase signature 149 160 2.3E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 NPD12_3485 5c5fce740559d8ceb2686faec9d3b3a7 478 PRINTS PR01046 Prolyl-tRNA synthetase signature 110 121 2.3E-9 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 NPD12_730 e776ffbe2f1bd6fa95df9b585370349c 126 SMART SM00345 15 74 1.7E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_730 e776ffbe2f1bd6fa95df9b585370349c 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.7E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_730 e776ffbe2f1bd6fa95df9b585370349c 126 Gene3D G3DSA:1.10.10.10 8 125 1.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_730 e776ffbe2f1bd6fa95df9b585370349c 126 SUPERFAMILY SSF46785 4 84 5.38E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_950 9fda823e091b5e40602dc8797cbb3633 316 Gene3D G3DSA:1.10.101.10 242 316 3.4E-21 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_950 9fda823e091b5e40602dc8797cbb3633 316 Gene3D G3DSA:3.20.20.80 1 193 1.0E-59 T 12-10-2018 NPD12_950 9fda823e091b5e40602dc8797cbb3633 316 SUPERFAMILY SSF47090 241 312 2.25E-19 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_950 9fda823e091b5e40602dc8797cbb3633 316 SUPERFAMILY SSF51445 3 202 4.98E-49 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_950 9fda823e091b5e40602dc8797cbb3633 316 Pfam PF01183 Glycosyl hydrolases family 25 5 182 8.4E-31 T 12-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 NPD12_950 9fda823e091b5e40602dc8797cbb3633 316 SMART SM00641 2 109 1.0E-5 T 12-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup NPD12_950 9fda823e091b5e40602dc8797cbb3633 316 Pfam PF01471 Putative peptidoglycan binding domain 258 311 1.1E-13 T 12-10-2018 IPR002477 Peptidoglycan binding-like NPD12_2830 4c0492f5a1ec84fe7a97231bc308ab8d 498 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 14 471 1.2E-149 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 NPD12_2830 4c0492f5a1ec84fe7a97231bc308ab8d 498 PIRSF PIRSF005690 1 486 3.1E-154 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Pfam PF00013 KH domain 555 613 2.7E-6 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 693 29.004 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Gene3D G3DSA:3.30.230.70 1 228 1.8E-71 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SUPERFAMILY SSF54211 290 486 1.42E-47 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 691 4.9E-290 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Gene3D G3DSA:2.40.50.140 622 692 3.4E-26 T 12-10-2018 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Pfam PF03725 3' exoribonuclease family, domain 2 145 207 3.3E-13 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SUPERFAMILY SSF55666 136 228 2.49E-25 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 5.5E-14 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Pfam PF01138 3' exoribonuclease family, domain 1 320 453 1.4E-19 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 239 317 2.0E-18 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SMART SM00316 620 690 3.6E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SUPERFAMILY SSF50249 609 693 1.11E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SUPERFAMILY SSF54791 551 629 4.17E-15 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Gene3D G3DSA:3.30.230.70 232 548 1.1E-115 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 PIRSF PIRSF005499 1 702 1.4E-277 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SMART SM00322 551 617 1.4E-9 T 12-10-2018 IPR004087 K Homology domain GO:0003676 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SUPERFAMILY SSF55666 447 548 9.03E-25 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Gene3D G3DSA:3.30.1370.10 549 621 1.2E-15 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SUPERFAMILY SSF46915 237 317 3.14E-19 T 12-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 SUPERFAMILY SSF54211 4 142 2.43E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_2460 93b3fee157d4fbf1b066a584c17bf8b1 702 Pfam PF00575 S1 RNA binding domain 621 690 9.1E-18 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_256 d90f3d2337e5352c49239d0c18db3776 1350 Gene3D G3DSA:3.40.50.300 1032 1230 1.2E-26 T 12-10-2018 NPD12_256 d90f3d2337e5352c49239d0c18db3776 1350 Pfam PF13086 AAA domain 266 394 3.1E-8 T 12-10-2018 NPD12_256 d90f3d2337e5352c49239d0c18db3776 1350 Gene3D G3DSA:3.40.50.300 198 466 1.8E-21 T 12-10-2018 NPD12_256 d90f3d2337e5352c49239d0c18db3776 1350 SUPERFAMILY SSF52540 258 1205 3.1E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_256 d90f3d2337e5352c49239d0c18db3776 1350 Pfam PF13087 AAA domain 1011 1194 3.4E-17 T 12-10-2018 NPD12_256 d90f3d2337e5352c49239d0c18db3776 1350 Gene3D G3DSA:3.40.960.10 1233 1332 1.4E-6 T 12-10-2018 NPD12_1909 b8fd6d54431495c268df85fcfccebadf 174 Gene3D G3DSA:3.30.1330.130 1 133 3.1E-41 T 12-10-2018 NPD12_1909 b8fd6d54431495c268df85fcfccebadf 174 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 140 172 2.0E-6 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 NPD12_1909 b8fd6d54431495c268df85fcfccebadf 174 SUPERFAMILY SSF143555 3 137 1.57E-45 T 12-10-2018 NPD12_1909 b8fd6d54431495c268df85fcfccebadf 174 PIRSF PIRSF006578 1 110 2.0E-45 T 12-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E NPD12_1909 b8fd6d54431495c268df85fcfccebadf 174 PIRSF PIRSF006578 99 173 2.0E-19 T 12-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E NPD12_1909 b8fd6d54431495c268df85fcfccebadf 174 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 12 121 5.0E-33 T 12-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain NPD12_2201 04789d3e22cc600f6c929fe478eec905 65 Pfam PF07505 Protein of unknown function (DUF5131) 2 35 7.8E-8 T 12-10-2018 IPR011101 Protein of unknown function DUF5131 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 SUPERFAMILY SSF47757 2 65 4.58E-13 T 12-10-2018 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 Gene3D G3DSA:3.40.50.150 65 256 1.3E-63 T 12-10-2018 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 SMART SM00138 2 254 5.2E-90 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 Gene3D G3DSA:1.10.155.10 1 64 3.3E-6 T 12-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 Pfam PF03705 CheR methyltransferase, all-alpha domain 2 53 2.8E-14 T 12-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 2.6E-39 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 PRINTS PR00996 Glutamate methyltransferase family signature 59 71 2.6E-39 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 PRINTS PR00996 Glutamate methyltransferase family signature 195 209 2.6E-39 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 PRINTS PR00996 Glutamate methyltransferase family signature 22 35 2.6E-39 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 2.6E-39 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 PRINTS PR00996 Glutamate methyltransferase family signature 214 237 2.6E-39 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 Pfam PF01739 CheR methyltransferase, SAM binding domain 66 242 8.6E-60 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal NPD12_2782 f4a2368cf215ba01072dd93a45577e14 256 SUPERFAMILY SSF53335 66 255 5.42E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_682 fa9eb2d42d68b14cf8db7f3ff9e99fcf 668 PIRSF PIRSF000906 11 657 0.0 T 12-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 NPD12_682 fa9eb2d42d68b14cf8db7f3ff9e99fcf 668 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 15 656 40.576 T 12-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 NPD12_682 fa9eb2d42d68b14cf8db7f3ff9e99fcf 668 SUPERFAMILY SSF56300 195 250 2.46E-5 T 12-10-2018 NPD12_682 fa9eb2d42d68b14cf8db7f3ff9e99fcf 668 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 17 655 0.0 T 12-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 ProSitePatterns PS01095 Chitinases family 18 active site. 139 147 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 SUPERFAMILY SSF49265 363 447 5.74E-11 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 SMART SM00060 367 436 1.7E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 Gene3D G3DSA:2.60.40.10 364 446 4.0E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 Pfam PF00704 Glycosyl hydrolases family 18 38 340 4.9E-30 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 SMART SM00636 36 340 8.2E-7 T 12-10-2018 IPR011583 Chitinase II GO:0008061 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 SUPERFAMILY SSF51055 454 497 1.96E-13 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 SUPERFAMILY SSF51445 33 349 7.7E-57 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 Gene3D G3DSA:3.20.20.80 31 360 2.6E-102 T 12-10-2018 NPD12_1250 509e06fb9507c8c95bd14f8722dce24f 499 Gene3D G3DSA:2.10.10.20 455 497 3.8E-17 T 12-10-2018 NPD12_2152 4af62ddcb7c22ab6a8334e08f6babb15 146 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain NPD12_2152 4af62ddcb7c22ab6a8334e08f6babb15 146 Gene3D G3DSA:3.40.930.10 1 146 1.0E-45 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 NPD12_2152 4af62ddcb7c22ab6a8334e08f6babb15 146 SUPERFAMILY SSF55804 1 146 7.72E-44 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 NPD12_2152 4af62ddcb7c22ab6a8334e08f6babb15 146 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 146 4.5E-42 T 12-10-2018 IPR002178 PTS EIIA type-2 domain NPD12_2152 4af62ddcb7c22ab6a8334e08f6babb15 146 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 133 6.4E-41 T 12-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Pfam PF00037 4Fe-4S binding domain 35 54 5.0E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Pfam PF00037 4Fe-4S binding domain 3 25 4.8E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 SMART SM00893 71 260 1.0E-58 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 SUPERFAMILY SSF52467 271 390 3.0E-48 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Gene3D G3DSA:3.40.50.1220 269 398 6.7E-57 T 12-10-2018 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 SUPERFAMILY SSF52402 69 265 1.05E-59 T 12-10-2018 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Gene3D G3DSA:3.40.50.620 69 268 9.6E-83 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 335 361 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 272 354 4.0E-34 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 SUPERFAMILY SSF54862 3 58 4.19E-19 T 12-10-2018 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Pfam PF01012 Electron transfer flavoprotein domain 71 250 3.7E-51 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 PIRSF PIRSF000089 67 396 4.9E-122 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Gene3D G3DSA:3.30.70.20 34 68 4.3E-6 T 12-10-2018 NPD12_3414 c7a5cdfa2fd9eb4bcaa90b12c2c86fa9 398 Gene3D G3DSA:3.30.70.20 1 33 1.5E-5 T 12-10-2018 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.3E-27 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.2E-77 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 5.1E-26 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 2.0E-21 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.683 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 Gene3D G3DSA:2.40.50.140 64 127 5.3E-26 T 12-10-2018 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 SUPERFAMILY SSF50249 65 129 7.71E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 SMART SM00841 129 184 4.2E-34 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 SMART SM01185 67 121 3.6E-25 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 SUPERFAMILY SSF50249 128 185 2.57E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 SUPERFAMILY SSF50104 1 62 3.79E-20 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 PIRSF PIRSF005901 1 185 1.1E-68 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 Gene3D G3DSA:2.40.50.140 128 185 2.8E-28 T 12-10-2018 NPD12_2063 4a5e26ffa85a208d6286843dd5f2530d 185 Gene3D G3DSA:2.30.30.30 1 63 5.2E-27 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 NPD12_217 64805280bbcafe3b1a4e9bf8a88070b1 56 Gene3D G3DSA:3.30.70.20 2 56 4.5E-24 T 12-10-2018 NPD12_217 64805280bbcafe3b1a4e9bf8a88070b1 56 PRINTS PR00354 7Fe ferredoxin signature 17 27 4.7E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 NPD12_217 64805280bbcafe3b1a4e9bf8a88070b1 56 PRINTS PR00354 7Fe ferredoxin signature 33 50 4.7E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 NPD12_217 64805280bbcafe3b1a4e9bf8a88070b1 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_217 64805280bbcafe3b1a4e9bf8a88070b1 56 Pfam PF12838 4Fe-4S dicluster domain 8 52 2.0E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_217 64805280bbcafe3b1a4e9bf8a88070b1 56 SUPERFAMILY SSF54862 3 54 2.33E-18 T 12-10-2018 NPD12_1676 cf15e18d5d2e2797cea039949f503a31 268 Gene3D G3DSA:3.40.190.10 130 229 4.0E-62 T 12-10-2018 NPD12_1676 cf15e18d5d2e2797cea039949f503a31 268 SUPERFAMILY SSF53850 5 264 4.35E-60 T 12-10-2018 NPD12_1676 cf15e18d5d2e2797cea039949f503a31 268 SMART SM00062 45 267 3.3E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_1676 cf15e18d5d2e2797cea039949f503a31 268 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 69 82 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site NPD12_1676 cf15e18d5d2e2797cea039949f503a31 268 Gene3D G3DSA:3.40.190.10 43 263 4.0E-62 T 12-10-2018 NPD12_1676 cf15e18d5d2e2797cea039949f503a31 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 264 8.3E-55 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_1679 44050c69b5c674a542b04029007255ca 670 Gene3D G3DSA:1.10.486.10 370 516 3.8E-80 T 12-10-2018 NPD12_1679 44050c69b5c674a542b04029007255ca 670 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 258 1.0E-49 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 NPD12_1679 44050c69b5c674a542b04029007255ca 670 Gene3D G3DSA:3.40.50.300 7 260 2.2E-69 T 12-10-2018 NPD12_1679 44050c69b5c674a542b04029007255ca 670 Gene3D G3DSA:1.10.10.160 104 175 2.2E-69 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily NPD12_1679 44050c69b5c674a542b04029007255ca 670 SUPERFAMILY SSF52540 6 596 2.3E-127 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1679 44050c69b5c674a542b04029007255ca 670 Gene3D G3DSA:3.40.50.300 269 604 3.8E-80 T 12-10-2018 NPD12_1679 44050c69b5c674a542b04029007255ca 670 Pfam PF13361 UvrD-like helicase C-terminal domain 264 587 7.3E-48 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 NPD12_2713 ef1f4a9c968ebef13cae680c14ff8d23 104 Pfam PF02049 Flagellar hook-basal body complex protein FliE 22 104 4.4E-28 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 NPD12_2713 ef1f4a9c968ebef13cae680c14ff8d23 104 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 14 103 3.8E-23 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 NPD12_2713 ef1f4a9c968ebef13cae680c14ff8d23 104 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 1 104 18.321 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 NPD12_2713 ef1f4a9c968ebef13cae680c14ff8d23 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 68 84 7.4E-13 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 NPD12_2713 ef1f4a9c968ebef13cae680c14ff8d23 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 34 50 7.4E-13 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 NPD12_2713 ef1f4a9c968ebef13cae680c14ff8d23 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 89 102 7.4E-13 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 NPD12_200 4435813c6128f8fc2c2f675e7eb2e077 247 Gene3D G3DSA:1.10.4030.30 4 65 1.7E-5 T 12-10-2018 NPD12_200 4435813c6128f8fc2c2f675e7eb2e077 247 SUPERFAMILY SSF109998 3 142 6.28E-21 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily NPD12_200 4435813c6128f8fc2c2f675e7eb2e077 247 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 142 162 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 NPD12_200 4435813c6128f8fc2c2f675e7eb2e077 247 Gene3D G3DSA:3.10.50.40 113 202 5.7E-33 T 12-10-2018 NPD12_200 4435813c6128f8fc2c2f675e7eb2e077 247 Pfam PF13616 PPIC-type PPIASE domain 107 202 1.1E-22 T 12-10-2018 NPD12_200 4435813c6128f8fc2c2f675e7eb2e077 247 SUPERFAMILY SSF54534 102 201 1.57E-29 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 Gene3D G3DSA:3.30.420.40 194 348 2.8E-89 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 Pfam PF14450 Cell division protein FtsA 204 365 1.2E-18 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 SUPERFAMILY SSF53067 196 366 2.52E-31 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 Gene3D G3DSA:3.30.420.40 8 353 2.8E-89 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 Gene3D G3DSA:3.30.1490.110 80 166 2.8E-89 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 SMART SM00842 5 193 5.8E-69 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 5 368 2.1E-93 T 12-10-2018 IPR020823 Cell division protein FtsA NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 Gene3D G3DSA:3.90.640.10 232 296 2.8E-89 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 Pfam PF02491 SHS2 domain inserted in FTSA 86 158 1.5E-22 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 SUPERFAMILY SSF53067 3 194 1.19E-45 T 12-10-2018 NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 PIRSF PIRSF003101 1 417 1.2E-109 T 12-10-2018 IPR020823 Cell division protein FtsA NPD12_2583 676d892e5ad4d53b32dbf9529f47207b 417 Hamap MF_02033 Cell division protein FtsA [ftsA]. 1 417 26.217 T 12-10-2018 IPR020823 Cell division protein FtsA NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Gene3D G3DSA:3.40.50.11270 12 98 3.7E-95 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Pfam PF02401 LytB protein 3 275 4.3E-91 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 276 3.0E-96 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SUPERFAMILY SSF50249 288 397 2.93E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Pfam PF00575 S1 RNA binding domain 561 633 1.6E-20 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Pfam PF00575 S1 RNA binding domain 476 547 3.0E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Pfam PF00575 S1 RNA binding domain 302 372 2.4E-11 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Gene3D G3DSA:2.40.50.140 289 385 3.1E-20 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SUPERFAMILY SSF50249 547 635 9.81E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SUPERFAMILY SSF50249 477 564 4.1E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Gene3D G3DSA:2.40.50.140 559 638 8.9E-26 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Gene3D G3DSA:2.40.50.140 474 557 9.9E-29 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 279 32.398 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SMART SM00316 301 372 4.8E-16 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SMART SM00316 477 547 3.9E-28 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SMART SM00316 388 458 0.33 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SMART SM00316 562 633 5.9E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 PRINTS PR00681 Ribosomal protein S1 signature 411 428 2.5E-38 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 PRINTS PR00681 Ribosomal protein S1 signature 577 596 2.5E-38 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 PRINTS PR00681 Ribosomal protein S1 signature 616 634 2.5E-38 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 PRINTS PR00681 Ribosomal protein S1 signature 321 335 2.5E-38 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 PRINTS PR00681 Ribosomal protein S1 signature 369 388 2.5E-38 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 PRINTS PR00681 Ribosomal protein S1 signature 303 321 2.5E-38 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 PRINTS PR00681 Ribosomal protein S1 signature 499 520 2.5E-38 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Gene3D G3DSA:3.40.1010.20 3 275 3.7E-95 T 12-10-2018 NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 SUPERFAMILY SSF50249 379 458 3.63E-5 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1957 e8c6136c465f9cd3fb05254c7b357c67 638 Gene3D G3DSA:3.40.1010.20 99 189 3.7E-95 T 12-10-2018 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 Gene3D G3DSA:3.40.50.720 3 246 2.0E-79 T 12-10-2018 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 114 247 2.3E-43 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 SUPERFAMILY SSF55347 113 219 2.83E-31 T 12-10-2018 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 PIRSF PIRSF000161 1 250 1.7E-82 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 SUPERFAMILY SSF51735 1 248 4.3E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 111 1.7E-28 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 136 153 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 248 31.038 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 Gene3D G3DSA:3.30.360.10 113 217 2.0E-79 T 12-10-2018 NPD12_3266 d038395e635af61f2bdf3acbac15a549 251 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 247 3.9E-66 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 SUPERFAMILY SSF50249 13 102 6.29E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 457 5.3E-87 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 Gene3D G3DSA:3.30.930.10 106 462 8.3E-115 T 12-10-2018 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 Pfam PF01336 OB-fold nucleic acid binding domain 21 98 9.0E-10 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 463 46.5 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 378 394 1.1E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 418 432 1.1E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 217 1.1E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 221 234 1.1E-12 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 Gene3D G3DSA:2.40.50.140 3 105 1.3E-19 T 12-10-2018 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 463 1.2E-192 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 NPD12_775 0049f90f6148dda17dc93314d01c5e55 463 SUPERFAMILY SSF55681 104 461 8.87E-98 T 12-10-2018 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 Gene3D G3DSA:3.40.640.10 62 284 2.0E-138 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 Gene3D G3DSA:3.90.1150.10 25 389 2.0E-138 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 SUPERFAMILY SSF53383 1 395 9.95E-117 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 7.6E-13 T 12-10-2018 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 7.6E-13 T 12-10-2018 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 7.6E-13 T 12-10-2018 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 7.6E-13 T 12-10-2018 NPD12_2446 8c5cf699b72f04eddec2d5f3b9fa037b 397 Pfam PF00155 Aminotransferase class I and II 31 389 4.1E-73 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_2816 2a7c0748525b4d390b8c11d3c8e9e1fb 345 Pfam PF02016 LD-carboxypeptidase 16 330 7.6E-66 T 12-10-2018 IPR003507 Peptidase family S66 NPD12_2816 2a7c0748525b4d390b8c11d3c8e9e1fb 345 SUPERFAMILY SSF52317 2 170 1.83E-41 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2816 2a7c0748525b4d390b8c11d3c8e9e1fb 345 Gene3D G3DSA:3.50.30.60 168 345 1.9E-54 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily NPD12_2816 2a7c0748525b4d390b8c11d3c8e9e1fb 345 SUPERFAMILY SSF141986 176 336 4.71E-26 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily NPD12_2816 2a7c0748525b4d390b8c11d3c8e9e1fb 345 Gene3D G3DSA:3.40.50.10740 2 167 9.4E-57 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal NPD12_2816 2a7c0748525b4d390b8c11d3c8e9e1fb 345 PIRSF PIRSF028757 4 344 3.7E-63 T 12-10-2018 IPR003507 Peptidase family S66 NPD12_1632 3c69d2b3425fdcc0fc4580b43b6c42b3 182 Gene3D G3DSA:3.30.70.270 16 182 6.9E-39 T 12-10-2018 NPD12_1632 3c69d2b3425fdcc0fc4580b43b6c42b3 182 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 28 179 2.0E-37 T 12-10-2018 IPR000160 GGDEF domain NPD12_1632 3c69d2b3425fdcc0fc4580b43b6c42b3 182 SMART SM00267 18 182 2.5E-22 T 12-10-2018 IPR000160 GGDEF domain NPD12_1632 3c69d2b3425fdcc0fc4580b43b6c42b3 182 Pfam PF00990 Diguanylate cyclase, GGDEF domain 29 180 1.0E-34 T 12-10-2018 IPR000160 GGDEF domain NPD12_1632 3c69d2b3425fdcc0fc4580b43b6c42b3 182 SUPERFAMILY SSF55073 34 179 1.57E-34 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_2269 93c0ceaf53434f06d0aa746593da06ee 212 TIGRFAM TIGR01076 sortase_fam: sortase 86 205 1.6E-27 T 12-10-2018 IPR005754 Sortase family NPD12_2269 93c0ceaf53434f06d0aa746593da06ee 212 Gene3D G3DSA:2.40.260.10 71 212 1.0E-40 T 12-10-2018 IPR023365 Sortase domain superfamily NPD12_2269 93c0ceaf53434f06d0aa746593da06ee 212 SUPERFAMILY SSF63817 74 210 5.76E-35 T 12-10-2018 IPR023365 Sortase domain superfamily NPD12_2269 93c0ceaf53434f06d0aa746593da06ee 212 Pfam PF04203 Sortase family 90 209 3.3E-27 T 12-10-2018 IPR005754 Sortase family NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 SUPERFAMILY SSF50447 216 333 4.5E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Gene3D G3DSA:3.30.70.870 336 411 8.2E-7 T 12-10-2018 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 SUPERFAMILY SSF54980 524 607 9.59E-16 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 SUPERFAMILY SSF54980 335 409 1.01E-11 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Gene3D G3DSA:2.40.30.10 239 335 1.7E-15 T 12-10-2018 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Pfam PF03764 Elongation factor G, domain IV 409 522 1.7E-19 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Gene3D G3DSA:3.40.50.300 1 238 9.0E-67 T 12-10-2018 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Gene3D G3DSA:3.30.230.10 429 606 2.1E-37 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 SUPERFAMILY SSF54211 408 522 1.63E-26 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 153 4.9E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 SMART SM00838 524 613 7.0E-5 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 SMART SM00889 408 522 7.1E-21 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Gene3D G3DSA:3.30.70.240 528 598 2.1E-37 T 12-10-2018 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 258 284 1.4E-14 T 12-10-2018 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 108 131 1.4E-14 T 12-10-2018 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 205 227 1.4E-14 T 12-10-2018 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Pfam PF00679 Elongation factor G C-terminus 524 607 5.5E-17 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 Pfam PF00009 Elongation factor Tu GTP binding domain 2 227 9.1E-54 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR00315 GTP-binding elongation factor signature 50 58 5.5E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR00315 GTP-binding elongation factor signature 122 131 5.5E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR00315 GTP-binding elongation factor signature 70 80 5.5E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR00315 GTP-binding elongation factor signature 86 97 5.5E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 PRINTS PR00315 GTP-binding elongation factor signature 4 17 5.5E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2236 33aa9f1a9f7664b93e60404a39034be9 651 SUPERFAMILY SSF52540 2 226 1.6E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.1E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.1E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 324 2.4E-33 T 12-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.5E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 Gene3D G3DSA:3.40.50.2300 161 290 3.3E-78 T 12-10-2018 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 Gene3D G3DSA:1.10.260.40 1 60 1.7E-24 T 12-10-2018 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 Gene3D G3DSA:3.40.50.2300 61 306 3.3E-78 T 12-10-2018 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 SUPERFAMILY SSF53822 61 331 2.55E-83 T 12-10-2018 IPR028082 Periplasmic binding protein-like I NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 SMART SM00354 2 72 4.1E-37 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 NPD12_255 c3daaaa38e403b4adb27a0adfe2774d3 332 SUPERFAMILY SSF47413 3 60 8.25E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1930 03355ea2117cff554c29ad72bfaccef1 421 SMART SM00487 22 221 7.6E-49 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_1930 03355ea2117cff554c29ad72bfaccef1 421 Gene3D G3DSA:3.40.50.300 217 421 1.3E-43 T 12-10-2018 NPD12_1930 03355ea2117cff554c29ad72bfaccef1 421 Pfam PF00271 Helicase conserved C-terminal domain 230 337 7.3E-26 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1930 03355ea2117cff554c29ad72bfaccef1 421 SMART SM00490 257 338 2.0E-25 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1930 03355ea2117cff554c29ad72bfaccef1 421 Pfam PF00270 DEAD/DEAH box helicase 27 191 7.9E-42 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_1930 03355ea2117cff554c29ad72bfaccef1 421 Gene3D G3DSA:3.40.50.300 1 216 3.4E-65 T 12-10-2018 NPD12_1930 03355ea2117cff554c29ad72bfaccef1 421 SUPERFAMILY SSF52540 71 359 1.23E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 PIRSF PIRSF006250 2 276 1.4E-97 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 SUPERFAMILY SSF51690 108 273 2.04E-60 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 273 2.4E-105 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 Gene3D G3DSA:3.90.1170.20 11 272 2.3E-110 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 19 106 1.3E-29 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 Gene3D G3DSA:3.20.20.70 122 264 2.3E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 108 273 7.1E-63 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 NPD12_1697 beef2eb0033f60c207ddda38ce6e128f 278 SUPERFAMILY SSF54675 1 107 4.71E-29 T 12-10-2018 NPD12_2773 52d697d4e7ab5dd5e6df4b9b7b7bb5f9 621 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 240 7.3E-65 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 NPD12_2773 52d697d4e7ab5dd5e6df4b9b7b7bb5f9 621 Pfam PF00460 Flagella basal body rod protein 8 37 5.6E-8 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 NPD12_2773 52d697d4e7ab5dd5e6df4b9b7b7bb5f9 621 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 564 617 4.0E-11 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain NPD12_2773 52d697d4e7ab5dd5e6df4b9b7b7bb5f9 621 SUPERFAMILY SSF64518 150 619 1.11E-18 T 12-10-2018 NPD12_2773 52d697d4e7ab5dd5e6df4b9b7b7bb5f9 621 PRINTS PR01005 Flagellar hook-associated protein signature 476 495 1.9E-6 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 NPD12_2773 52d697d4e7ab5dd5e6df4b9b7b7bb5f9 621 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 1.9E-6 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 NPD12_2773 52d697d4e7ab5dd5e6df4b9b7b7bb5f9 621 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 1.9E-6 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 Gene3D G3DSA:1.10.101.10 135 202 1.2E-6 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 SUPERFAMILY SSF47090 207 269 2.25E-13 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 Gene3D G3DSA:3.20.20.80 272 478 1.5E-47 T 12-10-2018 NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 SUPERFAMILY SSF51445 276 455 9.69E-36 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 SUPERFAMILY SSF47090 71 128 1.65E-5 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 Gene3D G3DSA:1.10.101.10 204 271 5.2E-10 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 Pfam PF01471 Putative peptidoglycan binding domain 213 265 9.6E-10 T 12-10-2018 IPR002477 Peptidoglycan binding-like NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 Pfam PF08924 Domain of unknown function (DUF1906) 289 408 2.5E-30 T 12-10-2018 IPR015020 Protein of unknown function DUF1906 NPD12_744 dd75b55be3cafc64319c4dcafc78bc02 695 Gene3D G3DSA:1.10.101.10 2 72 5.7E-6 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_39 30816b2aaee276a2d182a5193c3a3475 167 SUPERFAMILY SSF103642 144 165 4.25E-8 T 12-10-2018 NPD12_39 30816b2aaee276a2d182a5193c3a3475 167 Gene3D G3DSA:3.10.450.50 94 166 2.5E-11 T 12-10-2018 NPD12_39 30816b2aaee276a2d182a5193c3a3475 167 Pfam PF02810 SEC-C motif 147 165 2.5E-10 T 12-10-2018 IPR004027 SEC-C motif NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SUPERFAMILY SSF48452 71 219 2.39E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00028 277 310 10.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00028 395 428 90.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00028 75 108 58.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00028 155 188 170.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00028 197 230 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00028 237 270 23.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00028 355 388 140.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 Gene3D G3DSA:1.25.40.10 69 181 1.6E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 Gene3D G3DSA:1.25.40.10 189 429 9.4E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 Pfam PF12844 Helix-turn-helix domain 7 68 5.8E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SUPERFAMILY SSF48452 346 429 1.95E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 Gene3D G3DSA:1.10.260.40 4 68 1.3E-16 T 12-10-2018 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 Pfam PF13181 Tetratricopeptide repeat 197 219 0.014 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SMART SM00530 9 63 9.0E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SUPERFAMILY SSF47413 4 68 1.1E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 Pfam PF13424 Tetratricopeptide repeat 237 309 3.4E-9 T 12-10-2018 NPD12_569 56a4c79841a82b24e76ac91a2eeeb1f1 434 SUPERFAMILY SSF48452 176 351 3.03E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 Gene3D G3DSA:3.40.50.300 857 1053 1.2E-81 T 12-10-2018 NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 Gene3D G3DSA:3.40.50.10810 616 849 2.0E-66 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 Gene3D G3DSA:1.20.120.850 872 1091 1.2E-81 T 12-10-2018 NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 Pfam PF00271 Helicase conserved C-terminal domain 927 1039 1.5E-22 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 SMART SM00490 956 1039 9.4E-26 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 SUPERFAMILY SSF52540 852 1096 2.75E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 SUPERFAMILY SSF52540 633 850 5.91E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 SMART SM00487 643 826 1.1E-28 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 Pfam PF00176 SNF2 family N-terminal domain 665 916 5.4E-57 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 NPD12_1837 020f6a37496a8c6d28daf536ac805be9 1097 Pfam PF08455 Bacterial SNF2 helicase associated 245 640 2.7E-82 T 12-10-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial NPD12_792 5fe8700d8efb61a13f5daaed9a6579ef 347 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 9 335 5.7E-115 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_792 5fe8700d8efb61a13f5daaed9a6579ef 347 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 293 317 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_792 5fe8700d8efb61a13f5daaed9a6579ef 347 Pfam PF01098 Cell cycle protein 5 332 6.0E-101 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_792 5fe8700d8efb61a13f5daaed9a6579ef 347 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 1 338 26.631 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_314 fd3595f659a2e0c06ca16e753d641d4a 418 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 4.6E-169 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_314 fd3595f659a2e0c06ca16e753d641d4a 418 Gene3D G3DSA:3.65.10.10 6 414 2.3E-166 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 NPD12_314 fd3595f659a2e0c06ca16e753d641d4a 418 Gene3D G3DSA:3.65.10.10 21 231 2.3E-166 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 NPD12_314 fd3595f659a2e0c06ca16e753d641d4a 418 SUPERFAMILY SSF55205 1 417 2.78E-134 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 NPD12_314 fd3595f659a2e0c06ca16e753d641d4a 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 7.0E-101 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 NPD12_314 fd3595f659a2e0c06ca16e753d641d4a 418 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 43.316 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_2570 718746e1c7c6c199c5e62a8d77001b36 249 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 4 249 1.2E-129 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 NPD12_2570 718746e1c7c6c199c5e62a8d77001b36 249 Gene3D G3DSA:3.40.50.300 1 247 2.4E-65 T 12-10-2018 NPD12_2570 718746e1c7c6c199c5e62a8d77001b36 249 SMART SM00382 28 228 8.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2570 718746e1c7c6c199c5e62a8d77001b36 249 Pfam PF00005 ABC transporter 19 174 2.2E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2570 718746e1c7c6c199c5e62a8d77001b36 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2570 718746e1c7c6c199c5e62a8d77001b36 249 SUPERFAMILY SSF52540 2 236 2.6E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3424 87039f98929685912d211cffe125bc84 484 SMART SM00116 156 204 7.9E-9 T 12-10-2018 IPR000644 CBS domain NPD12_3424 87039f98929685912d211cffe125bc84 484 SMART SM00116 96 143 1.1E-9 T 12-10-2018 IPR000644 CBS domain NPD12_3424 87039f98929685912d211cffe125bc84 484 SUPERFAMILY SSF54631 85 202 1.01E-29 T 12-10-2018 NPD12_3424 87039f98929685912d211cffe125bc84 484 PIRSF PIRSF000130 1 484 9.4E-213 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 NPD12_3424 87039f98929685912d211cffe125bc84 484 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 NPD12_3424 87039f98929685912d211cffe125bc84 484 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 469 4.2E-165 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 NPD12_3424 87039f98929685912d211cffe125bc84 484 Gene3D G3DSA:3.20.20.70 1 482 1.9E-223 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3424 87039f98929685912d211cffe125bc84 484 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 482 85.188 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 NPD12_3424 87039f98929685912d211cffe125bc84 484 SUPERFAMILY SSF51412 2 473 2.09E-129 T 12-10-2018 NPD12_3424 87039f98929685912d211cffe125bc84 484 SMART SM01240 7 469 0.0 T 12-10-2018 NPD12_3424 87039f98929685912d211cffe125bc84 484 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 449 3.6E-199 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 NPD12_3424 87039f98929685912d211cffe125bc84 484 Pfam PF00571 CBS domain 149 199 9.3E-10 T 12-10-2018 IPR000644 CBS domain NPD12_3424 87039f98929685912d211cffe125bc84 484 Pfam PF00571 CBS domain 96 139 3.4E-10 T 12-10-2018 IPR000644 CBS domain NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 7 492 2.3E-141 T 12-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 Pfam PF12161 HsdM N-terminal domain 11 160 4.9E-21 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 Pfam PF02384 N-6 DNA Methylase 174 477 2.1E-114 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 295 301 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 Gene3D G3DSA:3.40.50.150 196 471 4.4E-90 T 12-10-2018 NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 SUPERFAMILY SSF53335 10 510 1.18E-134 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 Gene3D G3DSA:1.20.1260.30 2 192 5.7E-59 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 224 238 1.4E-25 T 12-10-2018 NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 214 1.4E-25 T 12-10-2018 NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 292 304 1.4E-25 T 12-10-2018 NPD12_2224 b2a25127b73be6269158fafe0bc134fb 511 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 328 352 1.4E-25 T 12-10-2018 NPD12_1840 e03ed6bc9f205032a0ca43ee9fd0d24b 329 SMART SM00342 240 323 3.7E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1840 e03ed6bc9f205032a0ca43ee9fd0d24b 329 Gene3D G3DSA:1.10.10.60 274 328 4.1E-17 T 12-10-2018 NPD12_1840 e03ed6bc9f205032a0ca43ee9fd0d24b 329 Pfam PF12833 Helix-turn-helix domain 246 324 2.5E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1840 e03ed6bc9f205032a0ca43ee9fd0d24b 329 Gene3D G3DSA:1.10.10.60 214 273 2.4E-11 T 12-10-2018 NPD12_1840 e03ed6bc9f205032a0ca43ee9fd0d24b 329 SUPERFAMILY SSF46689 225 274 1.39E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1840 e03ed6bc9f205032a0ca43ee9fd0d24b 329 SUPERFAMILY SSF46689 277 324 3.45E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3322 77e70e7577379609d83f0646a0c1226f 251 SUPERFAMILY SSF51695 4 237 6.8E-73 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 NPD12_3322 77e70e7577379609d83f0646a0c1226f 251 Gene3D G3DSA:3.20.20.190 1 242 1.1E-77 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 NPD12_3322 77e70e7577379609d83f0646a0c1226f 251 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 10 235 2.5E-42 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 Pfam PF02464 Competence-damaged protein 255 408 2.4E-56 T 12-10-2018 IPR008136 CinA, C-terminal NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 Pfam PF00994 Probable molybdopterin binding domain 5 170 2.6E-36 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 Gene3D G3DSA:3.40.980.10 1 171 5.4E-57 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 SUPERFAMILY SSF142433 249 408 6.8E-55 T 12-10-2018 IPR036653 CinA-like, C-terminal NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 408 6.7E-130 T 12-10-2018 IPR008135 Competence-induced protein CinA NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 165 1.7E-30 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 262 408 9.6E-45 T 12-10-2018 IPR008136 CinA, C-terminal NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 SMART SM00852 4 170 1.3E-42 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 SUPERFAMILY SSF53218 1 204 8.64E-42 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 Gene3D G3DSA:3.90.950.20 240 408 2.4E-55 T 12-10-2018 IPR036653 CinA-like, C-terminal NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 409 173.072 T 12-10-2018 IPR008135 Competence-induced protein CinA NPD12_369 5d8045e93589993b29bfe1be0d553dd8 409 PIRSF PIRSF006728 1 409 1.0E-159 T 12-10-2018 IPR008135 Competence-induced protein CinA NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 Pfam PF00005 ABC transporter 19 160 1.4E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 SUPERFAMILY SSF50331 236 357 3.97E-15 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 SMART SM00382 27 210 3.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 Gene3D G3DSA:2.40.50.100 239 355 3.9E-12 T 12-10-2018 NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 Gene3D G3DSA:3.40.50.300 1 237 1.9E-78 T 12-10-2018 NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 SUPERFAMILY SSF52540 3 241 6.21E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1758 1eaafb4be0075ce6c37743d10fb6ea82 365 Gene3D G3DSA:2.40.50.140 282 342 3.9E-12 T 12-10-2018 NPD12_1152 fc308becf8643243ad329249030a7d44 473 SUPERFAMILY SSF47384 238 321 2.55E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1152 fc308becf8643243ad329249030a7d44 473 Gene3D G3DSA:3.30.565.10 325 473 2.7E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1152 fc308becf8643243ad329249030a7d44 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 471 3.5E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1152 fc308becf8643243ad329249030a7d44 473 Gene3D G3DSA:1.10.287.130 194 315 3.5E-18 T 12-10-2018 NPD12_1152 fc308becf8643243ad329249030a7d44 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 316 7.5E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1152 fc308becf8643243ad329249030a7d44 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1152 fc308becf8643243ad329249030a7d44 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 473 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1152 fc308becf8643243ad329249030a7d44 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1152 fc308becf8643243ad329249030a7d44 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1152 fc308becf8643243ad329249030a7d44 473 SMART SM00388 253 321 1.1E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1152 fc308becf8643243ad329249030a7d44 473 SUPERFAMILY SSF55874 311 473 5.5E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1152 fc308becf8643243ad329249030a7d44 473 SMART SM00387 367 473 8.8E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 Pfam PF00472 RF-1 domain 188 297 5.4E-42 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 Gene3D G3DSA:1.20.58.410 1 82 6.1E-15 T 12-10-2018 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 Gene3D G3DSA:3.30.70.1660 89 317 1.5E-97 T 12-10-2018 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 204 220 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 SUPERFAMILY SSF75620 1 322 1.29E-126 T 12-10-2018 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 Pfam PF03462 PCRF domain 1 179 2.7E-58 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 SMART SM00937 45 154 4.1E-51 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 325 35.348 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 322 2.1E-147 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 NPD12_332 386add84964c44a32bd9b2e2e812b0f6 325 Gene3D G3DSA:3.30.160.20 185 280 1.5E-97 T 12-10-2018 NPD12_558 a3a0ad2579b1f242d4a74f0175b41f9a 112 PIRSF PIRSF002070 1 109 1.1E-31 T 12-10-2018 NPD12_558 a3a0ad2579b1f242d4a74f0175b41f9a 112 SUPERFAMILY SSF50249 1 105 5.36E-33 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_558 a3a0ad2579b1f242d4a74f0175b41f9a 112 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 104 2.7E-27 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 NPD12_558 a3a0ad2579b1f242d4a74f0175b41f9a 112 Gene3D G3DSA:2.40.50.140 1 110 1.8E-34 T 12-10-2018 NPD12_558 a3a0ad2579b1f242d4a74f0175b41f9a 112 Pfam PF00436 Single-strand binding protein family 1 101 4.3E-29 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 NPD12_558 a3a0ad2579b1f242d4a74f0175b41f9a 112 Hamap MF_00984 Single-stranded DNA-binding protein. 1 105 26.802 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 Gene3D G3DSA:3.30.1330.10 1 126 4.7E-41 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 SUPERFAMILY SSF56042 126 307 9.87E-51 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 Gene3D G3DSA:3.90.650.10 127 310 1.7E-56 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 PIRSF PIRSF036407 1 310 1.7E-118 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 TIGRFAM TIGR00476 selD: selenide, water dikinase 3 278 1.7E-111 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 Pfam PF00586 AIR synthase related protein, N-terminal domain 14 120 7.8E-20 T 12-10-2018 IPR016188 PurM-like, N-terminal domain NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 Hamap MF_00625 Selenide, water dikinase [selD]. 2 310 37.137 T 12-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 Pfam PF02769 AIR synthase related protein, C-terminal domain 132 309 2.4E-29 T 12-10-2018 IPR010918 PurM-like, C-terminal domain NPD12_3082 472bf8dcc26e2fbaa528f77e7734eaa3 310 SUPERFAMILY SSF55326 3 124 5.08E-38 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SMART SM00896 699 792 1.4E-49 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Gene3D G3DSA:3.30.930.10 490 685 3.1E-56 T 12-10-2018 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SUPERFAMILY SSF46955 406 478 3.75E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SMART SM00874 406 474 3.9E-24 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Gene3D G3DSA:3.30.56.10 407 478 3.4E-24 T 12-10-2018 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Pfam PF03484 tRNA synthetase B5 domain 411 474 1.4E-17 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Pfam PF03483 B3/4 domain 217 387 1.8E-67 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SUPERFAMILY SSF50249 41 192 1.49E-42 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SMART SM00873 216 389 4.1E-89 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Gene3D G3DSA:3.50.40.10 200 400 1.9E-83 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 792 9.7E-274 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SUPERFAMILY SSF55681 470 686 1.74E-47 T 12-10-2018 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SUPERFAMILY SSF54991 695 792 2.09E-33 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Pfam PF03147 Ferredoxin-fold anticodon binding domain 699 792 1.2E-32 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Gene3D G3DSA:3.30.70.380 700 793 1.5E-34 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 SUPERFAMILY SSF56037 204 399 3.66E-69 T 12-10-2018 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Gene3D G3DSA:3.30.56.10 5 183 7.4E-66 T 12-10-2018 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 786 42.58 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Gene3D G3DSA:2.40.50.140 39 156 7.4E-66 T 12-10-2018 NPD12_3238 d14f4d235da9384e3d6cbea4cdbf04b6 793 Pfam PF01588 Putative tRNA binding domain 45 147 2.8E-19 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 PRINTS PR00315 GTP-binding elongation factor signature 63 71 1.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 PRINTS PR00315 GTP-binding elongation factor signature 99 110 1.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 PRINTS PR00315 GTP-binding elongation factor signature 83 93 1.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 PRINTS PR00315 GTP-binding elongation factor signature 13 26 1.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 PRINTS PR00315 GTP-binding elongation factor signature 135 144 1.4E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 Gene3D G3DSA:3.40.50.300 70 377 4.1E-104 T 12-10-2018 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 Pfam PF16658 Class II release factor RF3, C-terminal domain 386 514 6.7E-49 T 12-10-2018 IPR032090 Peptide chain release factor 3, C-terminal NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 SUPERFAMILY SSF54980 392 465 9.35E-14 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 SUPERFAMILY SSF52540 8 273 6.79E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 Gene3D G3DSA:3.30.70.3280 389 528 1.6E-45 T 12-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 2 526 1.3E-210 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 146 4.1E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 SUPERFAMILY SSF50447 259 386 1.48E-27 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 Pfam PF00009 Elongation factor Tu GTP binding domain 11 274 1.3E-51 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 Pfam PF03144 Elongation factor Tu domain 2 312 378 1.0E-8 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 527 50.067 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 NPD12_3458 8c6468277c13eaec7caafed13cc2d983 529 Gene3D G3DSA:3.40.50.300 108 273 4.1E-104 T 12-10-2018 NPD12_1798 0cb8cdf320f85ce15b37b4c5bca30833 272 Pfam PF02517 CAAX protease self-immunity 134 220 3.2E-21 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_2381 2f807959ff9647e51094babb9067602e 318 SMART SM00876 228 318 5.3E-29 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_2381 2f807959ff9647e51094babb9067602e 318 SUPERFAMILY SSF102114 27 317 6.28E-68 T 12-10-2018 NPD12_2381 2f807959ff9647e51094babb9067602e 318 Hamap MF_01694 Biotin synthase [bioB]. 15 318 40.509 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_2381 2f807959ff9647e51094babb9067602e 318 SMART SM00729 52 257 1.2E-32 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_2381 2f807959ff9647e51094babb9067602e 318 PIRSF PIRSF001619 1 318 9.8E-109 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_2381 2f807959ff9647e51094babb9067602e 318 Pfam PF04055 Radical SAM superfamily 61 216 7.8E-17 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2381 2f807959ff9647e51094babb9067602e 318 Gene3D G3DSA:3.20.20.70 15 318 1.4E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2381 2f807959ff9647e51094babb9067602e 318 TIGRFAM TIGR00433 bioB: biotin synthase 25 317 2.0E-118 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_2381 2f807959ff9647e51094babb9067602e 318 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 228 317 3.4E-15 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_3029 0b0bb908529c4621c850aa197383cacc 40 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 5 38 1.4E-10 T 12-10-2018 IPR010022 Protein of unknown function XkdX NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 138 9.8E-30 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 Gene3D G3DSA:3.90.1170.50 37 138 2.3E-110 T 12-10-2018 NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 Gene3D G3DSA:3.30.365.10 376 754 2.9E-111 T 12-10-2018 NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 SMART SM01008 22 138 1.5E-46 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 Gene3D G3DSA:3.30.365.10 139 364 2.3E-110 T 12-10-2018 NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 SUPERFAMILY SSF54665 3 161 1.09E-44 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 700 9.3E-166 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 SUPERFAMILY SSF56003 142 760 4.19E-180 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 Gene3D G3DSA:3.30.365.10 458 614 2.9E-111 T 12-10-2018 NPD12_1534 9e53c538166ee8189f9fd9a7c9be53b7 765 Gene3D G3DSA:3.30.365.10 20 289 2.3E-110 T 12-10-2018 NPD12_1526 351ada748167fb98b8b9b54c778ce3d0 112 Pfam PF14034 Sporulation protein YtrH 7 105 6.1E-36 T 12-10-2018 IPR025689 Sporulation protein YtrH NPD12_3034 533ea5af271e231058efc9b9d5649492 135 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 26 132 5.0E-27 T 12-10-2018 IPR020288 Protein of unknown function DUF2634 NPD12_3034 533ea5af271e231058efc9b9d5649492 135 Pfam PF10934 Protein of unknown function (DUF2634) 27 122 2.3E-32 T 12-10-2018 IPR020288 Protein of unknown function DUF2634 NPD12_3034 533ea5af271e231058efc9b9d5649492 135 SUPERFAMILY SSF160719 39 124 2.09E-10 T 12-10-2018 NPD12_3034 533ea5af271e231058efc9b9d5649492 135 Gene3D G3DSA:3.10.450.40 20 132 4.4E-6 T 12-10-2018 NPD12_914 a683f86376a06dd172ceae09413e2e48 380 SUPERFAMILY SSF53383 8 377 1.06E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_914 a683f86376a06dd172ceae09413e2e48 380 Gene3D G3DSA:3.90.1150.10 246 380 2.2E-50 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_914 a683f86376a06dd172ceae09413e2e48 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 377 8.3E-153 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 NPD12_914 a683f86376a06dd172ceae09413e2e48 380 Gene3D G3DSA:3.40.640.10 2 245 1.4E-92 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_914 a683f86376a06dd172ceae09413e2e48 380 PIRSF PIRSF001434 1 380 5.9E-143 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 NPD12_361 86534a1667a2b77aa13b726f187b721a 421 Pfam PF00571 CBS domain 289 345 6.7E-7 T 12-10-2018 IPR000644 CBS domain NPD12_361 86534a1667a2b77aa13b726f187b721a 421 Pfam PF00571 CBS domain 354 405 3.5E-8 T 12-10-2018 IPR000644 CBS domain NPD12_361 86534a1667a2b77aa13b726f187b721a 421 SMART SM00924 186 289 3.5E-34 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain NPD12_361 86534a1667a2b77aa13b726f187b721a 421 SMART SM00116 360 409 1.2 T 12-10-2018 IPR000644 CBS domain NPD12_361 86534a1667a2b77aa13b726f187b721a 421 SMART SM00116 296 349 2.0 T 12-10-2018 IPR000644 CBS domain NPD12_361 86534a1667a2b77aa13b726f187b721a 421 Gene3D G3DSA:3.10.580.10 285 409 2.4E-36 T 12-10-2018 NPD12_361 86534a1667a2b77aa13b726f187b721a 421 Pfam PF03448 MgtE intracellular N domain 186 287 2.6E-25 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain NPD12_361 86534a1667a2b77aa13b726f187b721a 421 SUPERFAMILY SSF54631 288 406 1.71E-25 T 12-10-2018 NPD12_361 86534a1667a2b77aa13b726f187b721a 421 SUPERFAMILY SSF158791 159 286 7.72E-30 T 12-10-2018 NPD12_361 86534a1667a2b77aa13b726f187b721a 421 Gene3D G3DSA:1.25.60.10 164 284 6.4E-25 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily NPD12_361 86534a1667a2b77aa13b726f187b721a 421 Pfam PF05239 PRC-barrel domain 6 71 3.2E-7 T 12-10-2018 IPR027275 PRC-barrel domain NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 Pfam PF01476 LysM domain 75 118 1.9E-12 T 12-10-2018 IPR018392 LysM domain NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 SUPERFAMILY SSF54106 73 118 3.14E-10 T 12-10-2018 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 Pfam PF01471 Putative peptidoglycan binding domain 9 65 7.4E-19 T 12-10-2018 IPR002477 Peptidoglycan binding-like NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 154 166 7.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 173 187 7.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 329 342 7.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 271 279 7.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 SMART SM00631 129 412 4.0E-22 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 SUPERFAMILY SSF53187 123 418 2.9E-57 T 12-10-2018 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 SUPERFAMILY SSF47090 2 66 5.23E-22 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 Pfam PF00246 Zinc carboxypeptidase 136 415 1.2E-38 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 Gene3D G3DSA:3.40.630.10 126 421 1.5E-59 T 12-10-2018 NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 Gene3D G3DSA:3.10.350.10 73 118 1.3E-18 T 12-10-2018 IPR036779 LysM domain superfamily NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 SMART SM00257 74 118 1.8E-15 T 12-10-2018 IPR018392 LysM domain NPD12_1638 f93cb53c140c2040e8579daaddbc7ff4 423 Gene3D G3DSA:1.10.101.10 1 72 2.2E-26 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_670 1f066def3a90365a69e9bd51404969a7 317 SMART SM00448 2 115 3.2E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_670 1f066def3a90365a69e9bd51404969a7 317 Gene3D G3DSA:3.40.50.2300 1 141 8.5E-24 T 12-10-2018 NPD12_670 1f066def3a90365a69e9bd51404969a7 317 SUPERFAMILY SSF52172 3 127 4.41E-24 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_670 1f066def3a90365a69e9bd51404969a7 317 Pfam PF00072 Response regulator receiver domain 4 115 3.6E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 SUPERFAMILY SSF52540 306 505 2.59E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 Pfam PF00005 ABC transporter 20 191 5.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 SUPERFAMILY SSF52540 4 246 3.53E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 Gene3D G3DSA:3.40.50.300 289 515 4.0E-42 T 12-10-2018 NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 Gene3D G3DSA:3.40.50.300 3 285 1.3E-66 T 12-10-2018 NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 Pfam PF12848 ABC transporter 230 315 1.5E-21 T 12-10-2018 IPR032781 ABC-transporter extension domain NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 Pfam PF00005 ABC transporter 341 469 1.6E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 SMART SM00382 28 238 1.0E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1999 a6ae23392ed410f84b7afba7055bd89a 518 SMART SM00382 349 518 2.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_297 3a6a5b6343b86e315a3e4534badb5658 150 SUPERFAMILY SSF52788 1 144 2.88E-32 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily NPD12_297 3a6a5b6343b86e315a3e4534badb5658 150 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 135 1.6E-26 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I NPD12_297 3a6a5b6343b86e315a3e4534badb5658 150 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 115 130 9.0E-6 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 NPD12_297 3a6a5b6343b86e315a3e4534badb5658 150 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 9.0E-6 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 NPD12_297 3a6a5b6343b86e315a3e4534badb5658 150 SMART SM00226 1 143 7.3E-25 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I NPD12_297 3a6a5b6343b86e315a3e4534badb5658 150 Gene3D G3DSA:3.40.50.2300 1 149 1.0E-39 T 12-10-2018 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Pfam PF08676 MutL C terminal dimerisation domain 479 622 3.6E-43 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 SMART SM00853 480 622 1.2E-48 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Gene3D G3DSA:2.30.42.20 481 664 6.7E-62 T 12-10-2018 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Gene3D G3DSA:3.30.1370.100 522 619 6.7E-62 T 12-10-2018 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 662 26.282 T 12-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 SUPERFAMILY SSF54211 191 326 3.53E-34 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 117 1.7E-13 T 12-10-2018 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Gene3D G3DSA:3.30.230.10 214 326 5.3E-33 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 SUPERFAMILY SSF118116 478 664 1.44E-53 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 210 326 8.2E-37 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 SUPERFAMILY SSF55874 3 214 9.82E-49 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 3.6E-96 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 SMART SM01340 209 327 5.9E-50 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 NPD12_1949 aec01b1fc7bd4c51c7e810b73835cceb 666 Gene3D G3DSA:3.30.565.10 3 213 3.1E-63 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2837 57111ed631954e9ea038335009159eae 136 Pfam PF00582 Universal stress protein family 5 136 4.7E-17 T 12-10-2018 IPR006016 UspA NPD12_2837 57111ed631954e9ea038335009159eae 136 PRINTS PR01438 Universal stress protein signature 3 21 3.9E-11 T 12-10-2018 IPR006015 Universal stress protein A NPD12_2837 57111ed631954e9ea038335009159eae 136 PRINTS PR01438 Universal stress protein signature 115 136 3.9E-11 T 12-10-2018 IPR006015 Universal stress protein A NPD12_2837 57111ed631954e9ea038335009159eae 136 PRINTS PR01438 Universal stress protein signature 98 110 3.9E-11 T 12-10-2018 IPR006015 Universal stress protein A NPD12_2837 57111ed631954e9ea038335009159eae 136 SUPERFAMILY SSF52402 5 136 3.1E-23 T 12-10-2018 NPD12_2837 57111ed631954e9ea038335009159eae 136 Gene3D G3DSA:3.40.50.620 2 136 1.9E-24 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_508 4d5f7fd1151e2f7554627366719473a0 360 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 130 2.4E-13 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 NPD12_508 4d5f7fd1151e2f7554627366719473a0 360 SUPERFAMILY SSF53092 3 130 2.27E-12 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_508 4d5f7fd1151e2f7554627366719473a0 360 Pfam PF00557 Metallopeptidase family M24 138 343 2.3E-58 T 12-10-2018 IPR000994 Peptidase M24 NPD12_508 4d5f7fd1151e2f7554627366719473a0 360 Gene3D G3DSA:3.90.230.10 131 360 7.5E-74 T 12-10-2018 NPD12_508 4d5f7fd1151e2f7554627366719473a0 360 SUPERFAMILY SSF55920 133 360 3.01E-70 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like NPD12_508 4d5f7fd1151e2f7554627366719473a0 360 Gene3D G3DSA:3.40.350.10 1 130 4.7E-20 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_1873 262c54b84dc33415f944822b2d50e725 463 Gene3D G3DSA:3.30.390.30 340 460 1.7E-47 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 1.5E-35 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 1.5E-35 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 1.5E-35 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.5E-35 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.5E-35 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 Gene3D G3DSA:3.50.50.60 152 273 3.2E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PIRSF PIRSF000350 1 461 3.1E-106 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 Gene3D G3DSA:3.50.50.60 3 329 3.2E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1873 262c54b84dc33415f944822b2d50e725 463 SUPERFAMILY SSF55424 337 460 3.26E-43 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 SUPERFAMILY SSF51905 1 316 1.62E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1873 262c54b84dc33415f944822b2d50e725 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 322 2.6E-75 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 460 4.2E-184 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 274 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.0E-72 T 12-10-2018 NPD12_1873 262c54b84dc33415f944822b2d50e725 463 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 450 5.8E-39 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 SUPERFAMILY SSF55347 139 285 9.55E-37 T 12-10-2018 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 318 334 6.4E-6 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 2 15 6.4E-6 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 121 135 6.4E-6 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 59 75 6.4E-6 T 12-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 143 240 6.0E-8 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 Gene3D G3DSA:3.30.360.10 139 342 2.8E-109 T 12-10-2018 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 130 4.2E-28 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 SUPERFAMILY SSF51735 1 176 7.77E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3216 35b92931f86df4a4802d72bbf2ec1cdc 369 Gene3D G3DSA:3.40.50.720 4 325 2.8E-109 T 12-10-2018 NPD12_704 d03e52e42eadd6dad56f2ba5b323b386 449 PIRSF PIRSF006060 1 449 2.1E-74 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_704 d03e52e42eadd6dad56f2ba5b323b386 449 Gene3D G3DSA:1.20.1740.10 5 448 3.6E-97 T 12-10-2018 NPD12_704 d03e52e42eadd6dad56f2ba5b323b386 449 Pfam PF13520 Amino acid permease 11 410 1.6E-58 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_3626 853dc3c6eb3887041b5ed6cf51e06a87 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.636 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z NPD12_3626 853dc3c6eb3887041b5ed6cf51e06a87 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.0E-26 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3626 853dc3c6eb3887041b5ed6cf51e06a87 61 SUPERFAMILY SSF57716 6 61 4.56E-20 T 12-10-2018 NPD12_3626 853dc3c6eb3887041b5ed6cf51e06a87 61 Gene3D G3DSA:4.10.830.10 1 61 8.7E-29 T 12-10-2018 NPD12_2849 48153be99759def38ae291dd8ad11430 438 SUPERFAMILY SSF46548 12 135 1.31E-25 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_2849 48153be99759def38ae291dd8ad11430 438 Gene3D G3DSA:3.50.50.60 126 255 5.3E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2849 48153be99759def38ae291dd8ad11430 438 Gene3D G3DSA:3.50.50.60 256 437 6.1E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2849 48153be99759def38ae291dd8ad11430 438 Gene3D G3DSA:1.10.1060.10 1 125 8.6E-36 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_2849 48153be99759def38ae291dd8ad11430 438 SUPERFAMILY SSF51971 125 355 3.35E-55 T 12-10-2018 NPD12_2849 48153be99759def38ae291dd8ad11430 438 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 8 112 1.6E-32 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 NPD12_2849 48153be99759def38ae291dd8ad11430 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 127 419 1.8E-25 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_2849 48153be99759def38ae291dd8ad11430 438 PRINTS PR00419 Adrenodoxin reductase family signature 294 307 1.4E-22 T 12-10-2018 NPD12_2849 48153be99759def38ae291dd8ad11430 438 PRINTS PR00419 Adrenodoxin reductase family signature 260 274 1.4E-22 T 12-10-2018 NPD12_2849 48153be99759def38ae291dd8ad11430 438 PRINTS PR00419 Adrenodoxin reductase family signature 150 163 1.4E-22 T 12-10-2018 NPD12_2849 48153be99759def38ae291dd8ad11430 438 PRINTS PR00419 Adrenodoxin reductase family signature 192 202 1.4E-22 T 12-10-2018 NPD12_2849 48153be99759def38ae291dd8ad11430 438 PRINTS PR00419 Adrenodoxin reductase family signature 127 149 1.4E-22 T 12-10-2018 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 SUPERFAMILY SSF81271 372 444 1.28E-24 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Gene3D G3DSA:1.10.3210.10 1 189 1.6E-86 T 12-10-2018 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Pfam PF04607 Region found in RelA / SpoT proteins 233 342 9.9E-37 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Pfam PF13328 HD domain 24 173 2.0E-52 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 24 720 1.0E-250 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Gene3D G3DSA:3.30.460.10 191 323 2.3E-51 T 12-10-2018 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Pfam PF13291 ACT domain 643 720 1.5E-18 T 12-10-2018 IPR002912 ACT domain NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 SUPERFAMILY SSF81301 178 389 9.81E-67 T 12-10-2018 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 SUPERFAMILY SSF55021 648 721 5.5E-6 T 12-10-2018 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Gene3D G3DSA:3.30.70.260 644 723 3.9E-12 T 12-10-2018 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 SMART SM00954 233 343 5.2E-64 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Gene3D G3DSA:3.10.20.30 378 449 5.8E-35 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 SUPERFAMILY SSF109604 3 188 2.76E-75 T 12-10-2018 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 Pfam PF02824 TGS domain 385 444 9.4E-23 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 NPD12_3168 a17c3efc92ca7a7c3a080333bb3c80b7 723 SMART SM00471 39 151 2.0E-10 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_2189 db675426176a5a87bf79cdabf89e23ac 362 Gene3D G3DSA:3.90.230.10 132 358 1.1E-72 T 12-10-2018 NPD12_2189 db675426176a5a87bf79cdabf89e23ac 362 Pfam PF00557 Metallopeptidase family M24 140 342 2.6E-57 T 12-10-2018 IPR000994 Peptidase M24 NPD12_2189 db675426176a5a87bf79cdabf89e23ac 362 SUPERFAMILY SSF55920 130 358 4.06E-70 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like NPD12_2189 db675426176a5a87bf79cdabf89e23ac 362 Gene3D G3DSA:3.40.350.10 3 131 9.9E-21 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_2189 db675426176a5a87bf79cdabf89e23ac 362 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 131 3.4E-14 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 NPD12_2189 db675426176a5a87bf79cdabf89e23ac 362 SUPERFAMILY SSF53092 4 130 8.2E-15 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 Gene3D G3DSA:3.30.565.10 325 461 2.2E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 SUPERFAMILY SSF55874 326 460 1.83E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 7.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 7.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 7.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 312 9.1E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 SMART SM00387 359 460 2.0E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 SUPERFAMILY SSF47384 234 311 1.29E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 Pfam PF00672 HAMP domain 199 246 1.2E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 457 3.2E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 Gene3D G3DSA:1.10.287.130 196 311 4.2E-22 T 12-10-2018 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 SMART SM00388 251 316 9.4E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 SMART SM00304 198 250 7.6E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_462 36ecc4debe4ecd5b9e5e69e5115fd1ac 461 SUPERFAMILY SSF158472 199 247 1.57E-9 T 12-10-2018 NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 Gene3D G3DSA:3.30.1330.10 2 164 2.1E-67 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 331 45.041 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 327 9.8E-31 T 12-10-2018 IPR010918 PurM-like, C-terminal domain NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 SUPERFAMILY SSF56042 165 328 8.22E-51 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 Gene3D G3DSA:3.90.650.10 165 331 1.4E-58 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 157 7.1E-15 T 12-10-2018 IPR016188 PurM-like, N-terminal domain NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 323 1.9E-131 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 NPD12_2929 a225bdaee4c8acb10cb72048f9b89eb5 331 SUPERFAMILY SSF55326 2 164 1.35E-50 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_3609 241b6af0defb6b21c0e0f235eba5301e 113 ProSitePatterns PS01167 Ribosomal protein L17 signature. 31 53 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3609 241b6af0defb6b21c0e0f235eba5301e 113 Gene3D G3DSA:3.90.1030.10 2 113 1.6E-49 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3609 241b6af0defb6b21c0e0f235eba5301e 113 SUPERFAMILY SSF64263 3 113 1.57E-46 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3609 241b6af0defb6b21c0e0f235eba5301e 113 Pfam PF01196 Ribosomal protein L17 17 113 2.1E-40 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3609 241b6af0defb6b21c0e0f235eba5301e 113 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 2 113 29.097 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3609 241b6af0defb6b21c0e0f235eba5301e 113 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 113 6.4E-48 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 353 1.2E-170 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 Gene3D G3DSA:3.30.160.20 209 295 3.8E-99 T 12-10-2018 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 SMART SM00937 63 177 5.6E-69 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 Gene3D G3DSA:1.20.58.410 4 93 1.8E-8 T 12-10-2018 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 Gene3D G3DSA:3.30.70.1660 110 340 3.8E-99 T 12-10-2018 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 Pfam PF03462 PCRF domain 8 202 9.0E-79 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 41.408 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 Pfam PF00472 RF-1 domain 210 319 2.9E-40 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 NPD12_293 fb308ad82c80e292b4051c724dcd2c75 358 SUPERFAMILY SSF75620 8 351 5.76E-141 T 12-10-2018 NPD12_2840 7d3340ec0f8f449b8943dc74b36dd49e 341 Pfam PF06725 3D domain 280 340 6.7E-24 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 NPD12_2840 7d3340ec0f8f449b8943dc74b36dd49e 341 Gene3D G3DSA:2.40.40.10 165 330 2.5E-7 T 12-10-2018 IPR036908 RlpA-like domain superfamily NPD12_2840 7d3340ec0f8f449b8943dc74b36dd49e 341 SUPERFAMILY SSF50685 278 330 2.06E-10 T 12-10-2018 IPR036908 RlpA-like domain superfamily NPD12_3625 6825f377136eac4eabcc6af8109233ea 132 Gene3D G3DSA:3.30.1490.10 75 132 1.3E-27 T 12-10-2018 NPD12_3625 6825f377136eac4eabcc6af8109233ea 132 Pfam PF00410 Ribosomal protein S8 5 132 1.3E-50 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3625 6825f377136eac4eabcc6af8109233ea 132 Gene3D G3DSA:3.30.1370.30 4 74 1.4E-26 T 12-10-2018 NPD12_3625 6825f377136eac4eabcc6af8109233ea 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3625 6825f377136eac4eabcc6af8109233ea 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.769 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3625 6825f377136eac4eabcc6af8109233ea 132 SUPERFAMILY SSF56047 2 132 7.46E-48 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_2431 a903e19855cad50cf25edcaf3f4d133a 450 SUPERFAMILY SSF81301 6 149 1.63E-40 T 12-10-2018 NPD12_2431 a903e19855cad50cf25edcaf3f4d133a 450 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 302 446 2.6E-10 T 12-10-2018 IPR032810 CCA-adding enzyme, C-terminal NPD12_2431 a903e19855cad50cf25edcaf3f4d133a 450 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 179 240 6.9E-17 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 NPD12_2431 a903e19855cad50cf25edcaf3f4d133a 450 Pfam PF01743 Poly A polymerase head domain 29 152 3.1E-36 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 NPD12_2431 a903e19855cad50cf25edcaf3f4d133a 450 Gene3D G3DSA:1.10.3090.10 152 442 6.4E-64 T 12-10-2018 NPD12_2431 a903e19855cad50cf25edcaf3f4d133a 450 SUPERFAMILY SSF81891 150 449 6.15E-54 T 12-10-2018 NPD12_2431 a903e19855cad50cf25edcaf3f4d133a 450 Gene3D G3DSA:3.30.460.10 10 151 1.4E-48 T 12-10-2018 NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 121 127 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 151 40.902 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 72 151 4.0E-32 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 Gene3D G3DSA:3.30.160.70 1 67 1.3E-11 T 12-10-2018 NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 SUPERFAMILY SSF46767 70 151 2.49E-31 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 71 150 7.6E-35 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 Gene3D G3DSA:1.10.10.10 70 155 7.9E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1773 473ad16e1c590b2b9dd091119d351e64 156 SUPERFAMILY SSF53155 5 76 6.67E-14 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 NPD12_1631 8c90287daf3725619e5cfa4440972135 588 Gene3D G3DSA:3.40.50.300 130 284 3.0E-111 T 12-10-2018 NPD12_1631 8c90287daf3725619e5cfa4440972135 588 Pfam PF00271 Helicase conserved C-terminal domain 302 405 3.7E-12 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1631 8c90287daf3725619e5cfa4440972135 588 Gene3D G3DSA:1.20.272.40 128 448 3.0E-111 T 12-10-2018 NPD12_1631 8c90287daf3725619e5cfa4440972135 588 Gene3D G3DSA:3.40.50.300 285 430 3.0E-111 T 12-10-2018 NPD12_1631 8c90287daf3725619e5cfa4440972135 588 Pfam PF12513 Mitochondrial degradasome RNA helicase subunit C terminal 538 584 3.3E-9 T 12-10-2018 IPR022192 Mitochondrial degradasome RNA helicase subunit, C-terminal domain GO:0016817 NPD12_1631 8c90287daf3725619e5cfa4440972135 588 SUPERFAMILY SSF52540 141 414 1.86E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1631 8c90287daf3725619e5cfa4440972135 588 SMART SM00490 316 405 1.6E-19 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_787 1bf4506ef14c52ca2a191d9fa3a96984 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 6.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_787 1bf4506ef14c52ca2a191d9fa3a96984 230 SUPERFAMILY SSF52172 4 188 8.75E-41 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_787 1bf4506ef14c52ca2a191d9fa3a96984 230 Gene3D G3DSA:1.10.10.10 133 230 1.6E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_787 1bf4506ef14c52ca2a191d9fa3a96984 230 Gene3D G3DSA:3.40.50.2300 1 132 4.0E-36 T 12-10-2018 NPD12_787 1bf4506ef14c52ca2a191d9fa3a96984 230 SMART SM00862 152 228 1.2E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_787 1bf4506ef14c52ca2a191d9fa3a96984 230 Pfam PF00072 Response regulator receiver domain 5 113 5.8E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_787 1bf4506ef14c52ca2a191d9fa3a96984 230 SMART SM00448 3 113 2.7E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 SMART SM00994 9 48 1.2E-23 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 Pfam PF06689 ClpX C4-type zinc finger 11 47 8.6E-21 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 387 4.1E-16 T 12-10-2018 IPR019489 Clp ATPase, C-terminal NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 SMART SM01086 311 404 8.8E-31 T 12-10-2018 IPR019489 Clp ATPase, C-terminal NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 403 4.9E-207 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.207 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 SUPERFAMILY SSF57716 10 45 2.0E-11 T 12-10-2018 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 SUPERFAMILY SSF52540 60 397 1.28E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 SMART SM00382 107 260 7.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 Gene3D G3DSA:3.30.50.30 2 49 2.6E-22 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 Gene3D G3DSA:1.10.8.60 310 412 2.9E-38 T 12-10-2018 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 Gene3D G3DSA:3.40.50.300 53 309 7.3E-110 T 12-10-2018 NPD12_3341 f9c9f28f90b3bc5c032bf58645bb709f 429 Pfam PF07724 AAA domain (Cdc48 subfamily) 107 305 6.3E-50 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3459 c400789f9d60d24713986aa3c082cfee 268 Gene3D G3DSA:3.30.1240.10 86 190 5.7E-86 T 12-10-2018 NPD12_3459 c400789f9d60d24713986aa3c082cfee 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 234 4.4E-26 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 NPD12_3459 c400789f9d60d24713986aa3c082cfee 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 261 1.8E-67 T 12-10-2018 IPR000150 Cof family GO:0016787 NPD12_3459 c400789f9d60d24713986aa3c082cfee 268 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 12-10-2018 NPD12_3459 c400789f9d60d24713986aa3c082cfee 268 Gene3D G3DSA:3.40.50.1000 3 261 5.7E-86 T 12-10-2018 IPR023214 HAD superfamily NPD12_3459 c400789f9d60d24713986aa3c082cfee 268 SUPERFAMILY SSF56784 1 266 7.01E-80 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_3459 c400789f9d60d24713986aa3c082cfee 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 261 2.7E-73 T 12-10-2018 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Pfam PF00158 Sigma-54 interaction domain 356 522 3.1E-70 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SUPERFAMILY SSF55785 107 210 6.13E-13 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Gene3D G3DSA:3.30.450.20 113 212 1.1E-16 T 12-10-2018 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 569 578 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Pfam PF00989 PAS fold 221 269 1.9E-9 T 12-10-2018 IPR013767 PAS fold GO:0006355 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Gene3D G3DSA:1.10.8.60 527 593 9.3E-26 T 12-10-2018 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SMART SM00091 220 286 1.8E-7 T 12-10-2018 IPR000014 PAS domain NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SMART SM00091 110 177 7.4E-7 T 12-10-2018 IPR000014 PAS domain NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SUPERFAMILY SSF46689 610 664 1.08E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Pfam PF00381 PTS HPr component phosphorylation site 4 88 1.1E-10 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Gene3D G3DSA:3.40.50.300 344 526 1.2E-64 T 12-10-2018 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Gene3D G3DSA:1.10.10.60 594 666 1.3E-6 T 12-10-2018 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Pfam PF13426 PAS domain 121 211 2.0E-7 T 12-10-2018 IPR000014 PAS domain NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 111 212 6.6E-10 T 12-10-2018 IPR000014 PAS domain NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 218 277 5.3E-9 T 12-10-2018 IPR000014 PAS domain NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Gene3D G3DSA:3.30.450.20 213 319 1.6E-13 T 12-10-2018 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SUPERFAMILY SSF55594 1 89 1.31E-7 T 12-10-2018 IPR035895 HPr-like superfamily NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SUPERFAMILY SSF55785 215 314 7.15E-13 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SUPERFAMILY SSF52540 355 599 1.21E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 380 393 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 Gene3D G3DSA:3.30.1340.10 1 92 7.5E-9 T 12-10-2018 IPR035895 HPr-like superfamily NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 SMART SM00382 376 520 1.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3597 dae2f6de215f719155a2a9f8366d2ad3 669 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 442 457 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_2694 746d274ac209577a0ba9da413b4b25c2 408 SMART SM00382 211 358 4.7E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2694 746d274ac209577a0ba9da413b4b25c2 408 Pfam PF00448 SRP54-type protein, GTPase domain 213 402 6.7E-43 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2694 746d274ac209577a0ba9da413b4b25c2 408 Gene3D G3DSA:1.20.120.1380 171 394 6.2E-68 T 12-10-2018 NPD12_2694 746d274ac209577a0ba9da413b4b25c2 408 SMART SM00962 212 403 9.3E-63 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2694 746d274ac209577a0ba9da413b4b25c2 408 Gene3D G3DSA:3.40.50.300 207 391 6.2E-68 T 12-10-2018 NPD12_2694 746d274ac209577a0ba9da413b4b25c2 408 SUPERFAMILY SSF52540 211 403 2.39E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2694 746d274ac209577a0ba9da413b4b25c2 408 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 299 1.7E-77 T 12-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 NPD12_3086 9f50076ae48e76b8141cf1de4cae2477 300 SUPERFAMILY SSF55120 72 298 7.81E-69 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3086 9f50076ae48e76b8141cf1de4cae2477 300 Pfam PF00849 RNA pseudouridylate synthase 88 240 1.5E-32 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3086 9f50076ae48e76b8141cf1de4cae2477 300 SUPERFAMILY SSF55174 20 65 2.55E-5 T 12-10-2018 NPD12_3086 9f50076ae48e76b8141cf1de4cae2477 300 Gene3D G3DSA:3.10.290.10 17 71 2.0E-5 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_3086 9f50076ae48e76b8141cf1de4cae2477 300 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 21 299 1.2E-83 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3086 9f50076ae48e76b8141cf1de4cae2477 300 Gene3D G3DSA:3.30.2350.10 80 300 6.9E-73 T 12-10-2018 NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 SMART SM00490 254 335 1.3E-34 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 Gene3D G3DSA:3.40.50.300 1 206 2.8E-73 T 12-10-2018 NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 SUPERFAMILY SSF52540 71 356 7.72E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 Pfam PF00270 DEAD/DEAH box helicase 26 192 3.9E-50 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 SMART SM00487 21 218 4.9E-60 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 Gene3D G3DSA:3.40.50.300 207 376 1.6E-51 T 12-10-2018 NPD12_2170 b12aa826f2c944c62634fab89ff6e367 376 Pfam PF00271 Helicase conserved C-terminal domain 227 335 2.2E-32 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_3589 ebb5b19653ec33c08553f34a43114642 282 Hamap MF_01499 Diadenylate cyclase [dacA]. 9 258 33.627 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 NPD12_3589 ebb5b19653ec33c08553f34a43114642 282 PIRSF PIRSF004793 8 272 3.8E-96 T 12-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 NPD12_3589 ebb5b19653ec33c08553f34a43114642 282 SUPERFAMILY SSF143597 44 244 1.01E-68 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily NPD12_3589 ebb5b19653ec33c08553f34a43114642 282 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 17 253 3.1E-77 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 NPD12_3589 ebb5b19653ec33c08553f34a43114642 282 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 123 239 6.9E-45 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal NPD12_3589 ebb5b19653ec33c08553f34a43114642 282 Gene3D G3DSA:3.40.1700.10 107 258 5.4E-60 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily NPD12_2989 e3b5f59ff9f9218f751ebc0afca9e98f 356 SUPERFAMILY SSF56112 13 339 4.23E-51 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_2989 e3b5f59ff9f9218f751ebc0afca9e98f 356 Gene3D G3DSA:3.30.200.20 8 112 5.7E-31 T 12-10-2018 NPD12_2989 e3b5f59ff9f9218f751ebc0afca9e98f 356 Pfam PF01636 Phosphotransferase enzyme family 67 271 1.1E-9 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase NPD12_2989 e3b5f59ff9f9218f751ebc0afca9e98f 356 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 36 339 3.5E-78 T 12-10-2018 IPR014255 Spore coat protein CotS NPD12_2989 e3b5f59ff9f9218f751ebc0afca9e98f 356 Gene3D G3DSA:3.90.1200.10 113 350 1.8E-53 T 12-10-2018 NPD12_3575 ceba362da96afd8421cec975512644af 131 PIRSF PIRSF011474 1 131 1.4E-42 T 12-10-2018 IPR009693 Glucitol operon activator NPD12_3575 ceba362da96afd8421cec975512644af 131 Pfam PF06923 Glucitol operon activator protein (GutM) 5 106 7.4E-37 T 12-10-2018 IPR009693 Glucitol operon activator NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 Pfam PF08529 NusA N-terminal domain 4 127 2.1E-41 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 347 4.5E-134 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 SUPERFAMILY SSF54814 203 280 2.16E-32 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 Gene3D G3DSA:2.40.50.140 140 201 1.5E-21 T 12-10-2018 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 418 30.54 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 Gene3D G3DSA:3.30.300.20 283 444 5.6E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 Gene3D G3DSA:3.30.300.20 202 280 2.9E-36 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 Pfam PF13184 NusA-like KH domain 233 301 1.7E-27 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 SUPERFAMILY SSF54814 285 346 3.34E-17 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 SUPERFAMILY SSF69705 1 129 6.28E-38 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 SUPERFAMILY SSF50249 136 202 7.61E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 SMART SM00322 307 398 0.66 T 12-10-2018 IPR004087 K Homology domain GO:0003676 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 SMART SM00322 233 306 1.4 T 12-10-2018 IPR004087 K Homology domain GO:0003676 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 Gene3D G3DSA:3.30.1480.10 1 132 1.6E-44 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 NPD12_2469 5aedea5deaa74cd4aae238cb44e971f5 457 SMART SM00316 137 203 0.0014 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 SUPERFAMILY SSF52540 10 419 4.9E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 Gene3D G3DSA:1.20.1580.10 94 337 2.0E-166 T 12-10-2018 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 ProSitePatterns PS00211 ABC transporters family signature. 337 351 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 SMART SM00382 477 717 0.0088 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 SMART SM00382 26 414 3.1 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 Gene3D G3DSA:1.20.1580.10 545 583 7.9E-107 T 12-10-2018 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 Gene3D G3DSA:3.40.50.300 9 438 2.0E-166 T 12-10-2018 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 Pfam PF00005 ABC transporter 468 671 3.5E-15 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 SUPERFAMILY SSF52540 458 721 9.18E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 Gene3D G3DSA:1.10.8.280 148 259 2.0E-166 T 12-10-2018 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 Gene3D G3DSA:3.40.50.300 463 747 7.9E-107 T 12-10-2018 NPD12_2853 6cfb31bcc2d7b25abda9025f97e73d1a 752 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1635 2b9c069c15c9c09b56acd9c6ae55c1a0 199 SUPERFAMILY SSF52540 4 195 1.05E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1635 2b9c069c15c9c09b56acd9c6ae55c1a0 199 Pfam PF00005 ABC transporter 16 147 1.8E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1635 2b9c069c15c9c09b56acd9c6ae55c1a0 199 ProSitePatterns PS00211 ABC transporters family signature. 120 134 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1635 2b9c069c15c9c09b56acd9c6ae55c1a0 199 SMART SM00382 25 197 3.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1635 2b9c069c15c9c09b56acd9c6ae55c1a0 199 Gene3D G3DSA:3.40.50.300 1 199 2.3E-50 T 12-10-2018 NPD12_2628 ead6caf2c60f61e551d5ceb77c6281ed 825 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 328 6.1E-102 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 NPD12_2628 ead6caf2c60f61e551d5ceb77c6281ed 825 Gene3D G3DSA:3.30.1490.20 1 183 7.6E-61 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 NPD12_2628 ead6caf2c60f61e551d5ceb77c6281ed 825 Pfam PF00391 PEP-utilising enzyme, mobile domain 744 815 4.2E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 NPD12_2628 ead6caf2c60f61e551d5ceb77c6281ed 825 SUPERFAMILY SSF52009 714 817 1.12E-30 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 NPD12_2628 ead6caf2c60f61e551d5ceb77c6281ed 825 Gene3D G3DSA:3.30.470.20 185 334 3.7E-42 T 12-10-2018 NPD12_2628 ead6caf2c60f61e551d5ceb77c6281ed 825 Gene3D G3DSA:3.50.30.10 715 825 1.4E-32 T 12-10-2018 NPD12_2628 ead6caf2c60f61e551d5ceb77c6281ed 825 SUPERFAMILY SSF56059 2 316 1.05E-95 T 12-10-2018 NPD12_1565 985fb745a0d786f299201a6456ed508a 40 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 5 37 9.9E-9 T 12-10-2018 IPR010022 Protein of unknown function XkdX NPD12_926 1a4528a055e61136f3f12b4b6739afda 179 Pfam PF04542 Sigma-70 region 2 20 71 5.9E-5 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_926 1a4528a055e61136f3f12b4b6739afda 179 Gene3D G3DSA:1.10.1740.10 2 106 8.8E-6 T 12-10-2018 NPD12_926 1a4528a055e61136f3f12b4b6739afda 179 SUPERFAMILY SSF88659 104 177 2.99E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_926 1a4528a055e61136f3f12b4b6739afda 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 175 3.9E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_926 1a4528a055e61136f3f12b4b6739afda 179 Gene3D G3DSA:1.10.10.10 107 178 1.9E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_926 1a4528a055e61136f3f12b4b6739afda 179 SUPERFAMILY SSF88946 2 76 2.49E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_1521 642eb0682528587b3caeae102ce2beae 264 SMART SM00420 8 60 5.8E-18 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1521 642eb0682528587b3caeae102ce2beae 264 Gene3D G3DSA:1.10.10.10 1 57 1.2E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1521 642eb0682528587b3caeae102ce2beae 264 Pfam PF08220 DeoR-like helix-turn-helix domain 8 62 2.2E-18 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1521 642eb0682528587b3caeae102ce2beae 264 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 NPD12_1521 642eb0682528587b3caeae102ce2beae 264 SUPERFAMILY SSF46785 8 62 5.71E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1521 642eb0682528587b3caeae102ce2beae 264 SMART SM01134 79 239 4.0E-58 T 12-10-2018 NPD12_1521 642eb0682528587b3caeae102ce2beae 264 SUPERFAMILY SSF100950 80 237 7.43E-28 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_1521 642eb0682528587b3caeae102ce2beae 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 5.0E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1521 642eb0682528587b3caeae102ce2beae 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 5.0E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1521 642eb0682528587b3caeae102ce2beae 264 Pfam PF00455 DeoR C terminal sensor domain 81 237 8.9E-44 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain NPD12_2447 e79c518402d16124a6fde21497c0fccb 118 Gene3D G3DSA:1.10.3730.20 2 118 3.1E-10 T 12-10-2018 NPD12_2447 e79c518402d16124a6fde21497c0fccb 118 SUPERFAMILY SSF103481 41 117 9.81E-15 T 12-10-2018 NPD12_2447 e79c518402d16124a6fde21497c0fccb 118 Pfam PF00892 EamA-like transporter family 49 116 1.3E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_439 6fc1da0945a59d227d37b1c127b618c6 160 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 16 135 5.0E-40 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_439 6fc1da0945a59d227d37b1c127b618c6 160 Gene3D G3DSA:2.70.70.10 3 160 6.2E-52 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_439 6fc1da0945a59d227d37b1c127b618c6 160 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 13 138 8.2E-46 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_439 6fc1da0945a59d227d37b1c127b618c6 160 SUPERFAMILY SSF51261 3 159 5.58E-51 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_439 6fc1da0945a59d227d37b1c127b618c6 160 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 77 89 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 SUPERFAMILY SSF46589 1 117 9.42E-26 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 111 5.6E-29 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 SUPERFAMILY SSF55681 121 422 3.38E-75 T 12-10-2018 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 Gene3D G3DSA:1.10.287.40 1 109 1.6E-29 T 12-10-2018 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 225 401 8.9E-27 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 418 6.2E-126 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 Gene3D G3DSA:3.30.930.10 110 425 7.4E-104 T 12-10-2018 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 267 279 1.8E-20 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 319 332 1.8E-20 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 279 292 1.8E-20 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 336 352 1.8E-20 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.8E-20 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_677 60dc627d7b75436a1cdeb47c3f6d034e 425 PIRSF PIRSF001529 1 425 6.7E-133 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_1424 871be362ad8416f608829845408ea3b6 63 Pfam PF08141 Small acid-soluble spore protein H family 1 57 3.6E-19 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 NPD12_1424 871be362ad8416f608829845408ea3b6 63 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 58 15.073 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 NPD12_1424 871be362ad8416f608829845408ea3b6 63 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 57 5.6E-26 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 NPD12_1424 871be362ad8416f608829845408ea3b6 63 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 57 0.002 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Gene3D G3DSA:2.120.10.90 493 804 8.8E-125 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 4 804 24.972 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 SMART SM00434 10 462 2.0E-288 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Gene3D G3DSA:1.10.268.10 367 455 7.6E-219 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 SUPERFAMILY SSF56719 30 485 3.14E-184 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Gene3D G3DSA:3.30.1360.40 235 330 7.6E-219 T 12-10-2018 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 802 1.9E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 608 651 5.2E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 553 597 2.4E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 655 701 3.2E-15 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 706 752 1.8E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 548 3.5E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 7 803 0.0 T 12-10-2018 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 SUPERFAMILY SSF101904 496 811 1.19E-109 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Gene3D G3DSA:3.90.199.10 31 484 7.6E-219 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 NPD12_134 aa1d47df7e442881b5430f98e53d6518 841 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 469 5.5E-163 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_2582 7603851df8219cac2666336f0c71977b 369 Pfam PF12327 FtsZ family, C-terminal domain 222 316 2.0E-37 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal NPD12_2582 7603851df8219cac2666336f0c71977b 369 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 359 39.298 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 NPD12_2582 7603851df8219cac2666336f0c71977b 369 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 7.5E-43 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 Gene3D G3DSA:3.30.1330.20 221 335 1.2E-42 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 332 1.1E-137 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 NPD12_2582 7603851df8219cac2666336f0c71977b 369 SMART SM00864 13 205 4.0E-116 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 NPD12_2582 7603851df8219cac2666336f0c71977b 369 SMART SM00865 207 324 2.0E-59 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 PRINTS PR00423 Cell division protein FtsZ signature 98 118 8.2E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 PRINTS PR00423 Cell division protein FtsZ signature 212 233 8.2E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 PRINTS PR00423 Cell division protein FtsZ signature 126 147 8.2E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 PRINTS PR00423 Cell division protein FtsZ signature 189 211 8.2E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 SUPERFAMILY SSF52490 12 208 1.03E-71 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 SUPERFAMILY SSF55307 204 319 1.56E-45 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 Gene3D G3DSA:3.40.50.1440 4 219 3.5E-83 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 NPD12_2582 7603851df8219cac2666336f0c71977b 369 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 NPD12_1720 d1b200ad2863155ffac3be9311094b69 362 Gene3D G3DSA:3.40.50.1970 4 172 6.2E-58 T 12-10-2018 NPD12_1720 d1b200ad2863155ffac3be9311094b69 362 SUPERFAMILY SSF56796 9 354 1.05E-95 T 12-10-2018 NPD12_1720 d1b200ad2863155ffac3be9311094b69 362 PIRSF PIRSF001455 5 361 1.7E-109 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 NPD12_1720 d1b200ad2863155ffac3be9311094b69 362 Pfam PF01761 3-dehydroquinate synthase 67 324 4.6E-93 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 NPD12_1720 d1b200ad2863155ffac3be9311094b69 362 Gene3D G3DSA:1.20.1090.10 173 358 3.3E-52 T 12-10-2018 NPD12_1720 d1b200ad2863155ffac3be9311094b69 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 352 2.6E-110 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 NPD12_1720 d1b200ad2863155ffac3be9311094b69 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 353 57.553 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 SMART SM00283 397 672 6.3E-68 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 SUPERFAMILY SSF58104 336 672 1.57E-67 T 12-10-2018 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 Gene3D G3DSA:1.20.1480.50 282 373 4.8E-13 T 12-10-2018 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 Pfam PF17203 Single cache domain 3 190 292 2.0E-13 T 12-10-2018 IPR033463 Single cache domain 3 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 SUPERFAMILY SSF103190 167 292 7.46E-20 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 SMART SM00304 316 368 7.2E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 Gene3D G3DSA:1.10.287.950 408 672 3.2E-62 T 12-10-2018 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 Pfam PF00672 HAMP domain 319 365 5.0E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 444 618 2.4E-42 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1968 573a59b4a8a6e2f7f768454e2c14b56c 673 Gene3D G3DSA:3.30.450.20 175 281 1.3E-7 T 12-10-2018 NPD12_3097 0928ed7bbc84eea774315828a8ad7f92 237 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 4 190 3.2E-53 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 NPD12_3097 0928ed7bbc84eea774315828a8ad7f92 237 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 4 220 6.9E-66 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 NPD12_2790 bc4e8db23adbf87a95757d34e4732726 213 SUPERFAMILY SSF56784 3 201 2.0E-24 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_2790 bc4e8db23adbf87a95757d34e4732726 213 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 192 5.0E-33 T 12-10-2018 NPD12_2790 bc4e8db23adbf87a95757d34e4732726 213 Gene3D G3DSA:3.40.50.1000 4 204 2.6E-39 T 12-10-2018 IPR023214 HAD superfamily NPD12_2790 bc4e8db23adbf87a95757d34e4732726 213 Gene3D G3DSA:1.20.1440.100 16 88 2.6E-39 T 12-10-2018 NPD12_2790 bc4e8db23adbf87a95757d34e4732726 213 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 4 203 1.4E-59 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like NPD12_2790 bc4e8db23adbf87a95757d34e4732726 213 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 190 4.2E-25 T 12-10-2018 NPD12_3317 acd49cadfabd738b33b0c872e11792e0 298 TIGRFAM TIGR00277 HDIG: HDIG domain 147 242 7.7E-10 T 12-10-2018 IPR006675 HDIG domain NPD12_3317 acd49cadfabd738b33b0c872e11792e0 298 Pfam PF01966 HD domain 149 268 2.5E-14 T 12-10-2018 IPR006674 HD domain NPD12_3317 acd49cadfabd738b33b0c872e11792e0 298 Gene3D G3DSA:1.10.3210.10 119 293 8.1E-17 T 12-10-2018 NPD12_3317 acd49cadfabd738b33b0c872e11792e0 298 SMART SM00471 144 278 2.9E-8 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_3317 acd49cadfabd738b33b0c872e11792e0 298 SUPERFAMILY SSF109604 140 267 2.9E-19 T 12-10-2018 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 SUPERFAMILY SSF46689 446 541 1.52E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 Gene3D G3DSA:1.10.10.60 489 542 4.6E-16 T 12-10-2018 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 505 522 8.2E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 522 542 8.2E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 Gene3D G3DSA:1.10.8.60 404 484 1.2E-22 T 12-10-2018 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 Pfam PF02954 Bacterial regulatory protein, Fis family 499 539 1.0E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 Gene3D G3DSA:3.40.50.300 216 403 1.7E-64 T 12-10-2018 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 SMART SM00382 252 396 1.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 446 455 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 Gene3D G3DSA:3.30.450.20 88 195 1.6E-10 T 12-10-2018 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 SUPERFAMILY SSF52540 231 474 2.92E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 Pfam PF00158 Sigma-54 interaction domain 232 399 7.0E-69 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 256 269 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_3307 48588f7580e0e48a4b602e30c7a5083b 542 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 319 334 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 SMART SM00304 314 366 1.5E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 Gene3D G3DSA:1.20.1480.50 278 372 3.3E-14 T 12-10-2018 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 SUPERFAMILY SSF58104 334 670 2.88E-68 T 12-10-2018 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 Pfam PF00672 HAMP domain 315 359 4.7E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 Pfam PF02743 Cache domain 36 277 2.0E-30 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 Gene3D G3DSA:3.30.450.20 156 277 5.9E-25 T 12-10-2018 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 473 624 1.6E-39 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 SMART SM00283 395 670 1.4E-66 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2517 3b95801c3e222fe2d4df87564c4a9ae4 672 Gene3D G3DSA:1.10.287.950 379 670 1.4E-63 T 12-10-2018 NPD12_2246 c616ca4b816a50df08ed706f23f8ec14 100 SMART SM00877 33 100 1.8E-7 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2246 c616ca4b816a50df08ed706f23f8ec14 100 Gene3D G3DSA:3.30.70.1710 1 100 2.4E-36 T 12-10-2018 NPD12_2246 c616ca4b816a50df08ed706f23f8ec14 100 Pfam PF00936 BMC domain 34 92 1.4E-6 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2246 c616ca4b816a50df08ed706f23f8ec14 100 SUPERFAMILY SSF143414 33 97 1.19E-9 T 12-10-2018 IPR037233 CcmK-like superfamily NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Pfam PF00122 E1-E2 ATPase 99 283 7.7E-57 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Gene3D G3DSA:3.40.50.1000 300 635 8.6E-300 T 12-10-2018 IPR023214 HAD superfamily NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 SUPERFAMILY SSF81660 309 500 1.37E-47 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 SUPERFAMILY SSF81665 6 842 8.24E-131 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 SUPERFAMILY SSF81653 102 203 3.01E-29 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Pfam PF00689 Cation transporting ATPase, C-terminus 674 843 2.0E-49 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Pfam PF00702 haloacid dehalogenase-like hydrolase 301 604 9.1E-24 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Gene3D G3DSA:1.20.1110.10 43 842 8.6E-300 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 303 317 5.2E-39 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 626 5.2E-39 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 488 499 5.2E-39 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 150 164 5.2E-39 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 609 5.2E-39 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 520 5.2E-39 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Gene3D G3DSA:3.40.1110.10 313 495 8.6E-300 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Pfam PF00690 Cation transporter/ATPase, N-terminus 7 60 7.0E-18 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 5 833 2.1E-161 T 12-10-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 305 311 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 Gene3D G3DSA:2.70.150.10 6 206 8.6E-300 T 12-10-2018 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 42 840 7.9E-213 T 12-10-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 562 578 1.5E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 622 647 1.5E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 590 606 1.5E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 450 468 1.5E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 SUPERFAMILY SSF56784 301 695 1.73E-55 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 562 680 1.8E-33 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 71 326 2.1E-52 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 393 535 7.7E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2684 c6125e748b78a63a930aead5ca2d52c9 848 SMART SM00831 2 65 7.8E-18 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_2243 299961577f4b334f9b252ec801b5bbff 265 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 2 48 9.0E-18 T 12-10-2018 NPD12_2243 299961577f4b334f9b252ec801b5bbff 265 Gene3D G3DSA:3.30.70.1710 1 112 3.2E-38 T 12-10-2018 NPD12_2243 299961577f4b334f9b252ec801b5bbff 265 Pfam PF00936 BMC domain 3 80 8.8E-25 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2243 299961577f4b334f9b252ec801b5bbff 265 SUPERFAMILY SSF143414 1 96 5.49E-30 T 12-10-2018 IPR037233 CcmK-like superfamily NPD12_2243 299961577f4b334f9b252ec801b5bbff 265 SMART SM00877 2 80 2.0E-32 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_3306 a13aae6efb934a9880f5c2e962125a05 324 Gene3D G3DSA:3.30.420.40 97 237 6.3E-85 T 12-10-2018 NPD12_3306 a13aae6efb934a9880f5c2e962125a05 324 Gene3D G3DSA:3.30.420.40 4 254 6.3E-85 T 12-10-2018 NPD12_3306 a13aae6efb934a9880f5c2e962125a05 324 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 254 5.1E-41 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_3306 a13aae6efb934a9880f5c2e962125a05 324 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 253 3.9E-52 T 12-10-2018 IPR008275 CoA enzyme activase NPD12_3306 a13aae6efb934a9880f5c2e962125a05 324 SUPERFAMILY SSF53067 2 254 3.0E-37 T 12-10-2018 NPD12_956 9d972cd2dfae08e6d97d6d3b6c7ea516 275 Gene3D G3DSA:3.40.1190.20 1 269 9.1E-102 T 12-10-2018 IPR029056 Ribokinase-like NPD12_956 9d972cd2dfae08e6d97d6d3b6c7ea516 275 SUPERFAMILY SSF53613 1 264 9.82E-83 T 12-10-2018 IPR029056 Ribokinase-like NPD12_956 9d972cd2dfae08e6d97d6d3b6c7ea516 275 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 256 3.8E-106 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_956 9d972cd2dfae08e6d97d6d3b6c7ea516 275 Pfam PF08543 Phosphomethylpyrimidine kinase 11 254 6.7E-96 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 250 7.9E-84 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 448 1.3E-62 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 Hamap MF_00186 Glycerol kinase [glpK]. 2 495 59.946 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 Gene3D G3DSA:3.30.420.40 1 251 8.5E-109 T 12-10-2018 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 360 380 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 494 7.8E-231 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 SUPERFAMILY SSF53067 253 494 2.85E-86 T 12-10-2018 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 Gene3D G3DSA:3.30.420.40 252 498 3.5E-90 T 12-10-2018 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 PIRSF PIRSF000538 2 498 2.7E-180 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 NPD12_2817 268e89c6ccdeadc7d767d2833a7d5f7d 498 SUPERFAMILY SSF53067 3 253 1.01E-94 T 12-10-2018 NPD12_1221 d10208d51963673447795dccc5ef8d40 73 SMART SM00899 2 73 3.6E-19 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1221 d10208d51963673447795dccc5ef8d40 73 Gene3D G3DSA:2.30.30.90 1 73 3.6E-24 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain NPD12_1221 d10208d51963673447795dccc5ef8d40 73 SUPERFAMILY SSF50037 6 73 9.16E-21 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal NPD12_1221 d10208d51963673447795dccc5ef8d40 73 Pfam PF04023 FeoA domain 2 73 8.2E-16 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Gene3D G3DSA:2.40.50.100 63 97 6.8E-9 T 12-10-2018 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Gene3D G3DSA:2.40.50.100 333 369 1.2E-17 T 12-10-2018 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 447 462 6.1E-20 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 76 96 6.1E-20 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 378 402 6.1E-20 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 402 425 6.1E-20 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 34 57 6.1E-20 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Pfam PF13533 Biotin-lipoyl like 73 105 7.9E-6 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Gene3D G3DSA:2.40.30.170 370 460 1.2E-17 T 12-10-2018 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Gene3D G3DSA:2.40.30.170 53 62 6.8E-9 T 12-10-2018 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Pfam PF13437 HlyD family secretion protein 332 450 2.5E-14 T 12-10-2018 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Gene3D G3DSA:1.10.287.470 237 332 1.2E-17 T 12-10-2018 NPD12_1404 2d8d3b6d75feb7447841d4351ae34d58 476 Gene3D G3DSA:1.10.287.470 98 177 6.8E-9 T 12-10-2018 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 3.1E-57 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 3.1E-57 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 3.1E-57 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 3.1E-57 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 3.1E-57 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 Pfam PF06723 MreB/Mbl protein 7 330 3.4E-150 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 Gene3D G3DSA:3.30.420.40 149 312 2.7E-130 T 12-10-2018 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 Gene3D G3DSA:3.90.640.10 181 254 2.7E-130 T 12-10-2018 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 330 6.6E-143 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 SUPERFAMILY SSF53067 7 141 2.88E-42 T 12-10-2018 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 Gene3D G3DSA:3.30.420.40 9 323 2.7E-130 T 12-10-2018 NPD12_318 6c0fe940fd649dc8ca921ecac7d84329 342 SUPERFAMILY SSF53067 144 328 1.57E-48 T 12-10-2018 NPD12_213 c1d691a382f8300ed1f69f72e5898358 109 Pfam PF06153 Cyclic-di-AMP receptor 1 108 4.7E-49 T 12-10-2018 IPR010375 Cyclic-di-AMP receptor NPD12_213 c1d691a382f8300ed1f69f72e5898358 109 SUPERFAMILY SSF54913 1 109 7.31E-13 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta NPD12_213 c1d691a382f8300ed1f69f72e5898358 109 Gene3D G3DSA:3.30.70.120 1 103 1.5E-41 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal NPD12_2485 25f30a5532149504899151cc76dafb19 696 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 281 304 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Gene3D G3DSA:3.40.50.140 1 134 2.1E-53 T 12-10-2018 NPD12_2485 25f30a5532149504899151cc76dafb19 696 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 1.7E-248 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Gene3D G3DSA:1.10.290.10 252 387 8.7E-166 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 NPD12_2485 25f30a5532149504899151cc76dafb19 696 SUPERFAMILY SSF57783 573 613 4.59E-14 T 12-10-2018 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Pfam PF01131 DNA topoisomerase 128 547 7.0E-136 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 SMART SM00493 3 103 3.9E-32 T 12-10-2018 IPR006171 TOPRIM domain NPD12_2485 25f30a5532149504899151cc76dafb19 696 Gene3D G3DSA:2.70.20.10 184 457 8.7E-166 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Gene3D G3DSA:3.30.65.10 559 618 2.0E-15 T 12-10-2018 NPD12_2485 25f30a5532149504899151cc76dafb19 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 295 304 1.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 1.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 1.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 372 388 1.2E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Pfam PF01751 Toprim domain 5 113 1.9E-30 T 12-10-2018 IPR006171 TOPRIM domain NPD12_2485 25f30a5532149504899151cc76dafb19 696 SMART SM00437 244 510 1.1E-119 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Gene3D G3DSA:1.10.460.10 135 550 8.7E-166 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 655 2.4E-15 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 612 1.2E-13 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 694 1.1E-4 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 NPD12_2485 25f30a5532149504899151cc76dafb19 696 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 642 55.239 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 SMART SM00436 104 192 1.1E-49 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 NPD12_2485 25f30a5532149504899151cc76dafb19 696 SUPERFAMILY SSF56712 4 589 6.67E-198 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain NPD12_1820 2775140b158636619065639c4e10f60e 566 SMART SM00450 454 549 1.7E-23 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 2.0E-22 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 2.0E-22 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.0E-22 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 2.0E-22 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.0E-22 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 SUPERFAMILY SSF52821 432 543 1.7E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1820 2775140b158636619065639c4e10f60e 566 Pfam PF00581 Rhodanese-like domain 464 541 2.2E-14 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1820 2775140b158636619065639c4e10f60e 566 Gene3D G3DSA:3.40.250.10 452 545 2.8E-25 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1820 2775140b158636619065639c4e10f60e 566 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 431 2.1E-15 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 NPD12_1820 2775140b158636619065639c4e10f60e 566 SUPERFAMILY SSF55424 322 447 3.78E-30 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 NPD12_1820 2775140b158636619065639c4e10f60e 566 Gene3D G3DSA:3.50.50.60 4 339 9.9E-170 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1820 2775140b158636619065639c4e10f60e 566 Gene3D G3DSA:3.50.50.60 116 441 9.9E-170 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1820 2775140b158636619065639c4e10f60e 566 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 305 9.9E-63 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_1820 2775140b158636619065639c4e10f60e 566 SUPERFAMILY SSF51905 2 316 2.44E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 3.3E-15 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 3.3E-15 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.3E-15 T 12-10-2018 NPD12_1820 2775140b158636619065639c4e10f60e 566 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 3.3E-15 T 12-10-2018 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1167 18.845 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1157 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 SMART SM00663 225 504 3.1E-183 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Gene3D G3DSA:1.10.132.30 637 771 3.9E-63 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Gene3D G3DSA:1.10.40.90 364 406 4.2E-25 T 12-10-2018 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Gene3D G3DSA:1.10.1790.20 927 1104 2.8E-71 T 12-10-2018 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Gene3D G3DSA:1.10.274.100 480 636 1.1E-47 T 12-10-2018 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 SUPERFAMILY SSF64484 5 1158 0.0 T 12-10-2018 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Pfam PF04983 RNA polymerase Rpb1, domain 3 479 640 5.3E-27 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Pfam PF00623 RNA polymerase Rpb1, domain 2 334 475 1.7E-37 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Pfam PF05000 RNA polymerase Rpb1, domain 4 669 735 1.3E-15 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Gene3D G3DSA:2.40.50.100 943 1005 2.8E-71 T 12-10-2018 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Gene3D G3DSA:1.10.150.390 1106 1168 1.4E-29 T 12-10-2018 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Pfam PF04998 RNA polymerase Rpb1, domain 5 747 1104 1.1E-68 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3646 ab66b5ba90b747bd16f97d138b8f5949 1178 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 332 7.1E-92 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 145 517 6.4E-164 T 12-10-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 229 513 2.3E-100 T 12-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Pfam PF13187 4Fe-4S dicluster domain 152 210 3.2E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 SMART SM00902 519 576 1.9E-27 T 12-10-2018 IPR003149 Iron hydrogenase, small subunit NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Pfam PF02256 Iron hydrogenase small subunit 523 576 2.3E-25 T 12-10-2018 IPR003149 Iron hydrogenase, small subunit NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Gene3D G3DSA:3.30.70.20 149 211 7.4E-158 T 12-10-2018 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 82 2.3E-18 T 12-10-2018 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 SUPERFAMILY SSF54292 3 90 4.99E-16 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 90 127 1.9E-17 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Gene3D G3DSA:3.40.50.1780 212 516 7.4E-158 T 12-10-2018 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 SUPERFAMILY SSF53920 195 574 2.75E-136 T 12-10-2018 IPR009016 Iron hydrogenase NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Gene3D G3DSA:3.40.950.10 278 507 7.4E-158 T 12-10-2018 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 SUPERFAMILY SSF54862 82 220 6.7E-39 T 12-10-2018 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Gene3D G3DSA:3.10.20.740 3 131 2.1E-41 T 12-10-2018 NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 Gene3D G3DSA:4.10.260.20 520 577 1.4E-20 T 12-10-2018 IPR036991 Iron hydrogenase, small subunit superfamily NPD12_2000 968ca8ed8618fde3b2a43d14b8e9d9ab 577 SMART SM00929 90 130 1.1E-18 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_1813 20c587445f95ea47dfdb98f24c99f4e4 110 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 106 7.0E-20 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 NPD12_1813 20c587445f95ea47dfdb98f24c99f4e4 110 Gene3D G3DSA:3.10.20.400 2 97 1.5E-41 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 NPD12_1813 20c587445f95ea47dfdb98f24c99f4e4 110 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 106 1.3E-36 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 NPD12_1813 20c587445f95ea47dfdb98f24c99f4e4 110 SUPERFAMILY SSF141734 6 108 6.54E-49 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 NPD12_1813 20c587445f95ea47dfdb98f24c99f4e4 110 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 110 31.046 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 445 463 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 249 536 4.4E-125 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 Gene3D G3DSA:3.20.20.60 232 538 1.1E-125 T 12-10-2018 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 SUPERFAMILY SSF47831 22 141 1.31E-35 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 PIRSF PIRSF000732 1 538 2.0E-221 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 291 310 1.9E-32 T 12-10-2018 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 498 510 1.9E-32 T 12-10-2018 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 462 477 1.9E-32 T 12-10-2018 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 445 460 1.9E-32 T 12-10-2018 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 182 193 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 SUPERFAMILY SSF52009 123 242 3.4E-38 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 Gene3D G3DSA:1.10.274.10 21 144 3.1E-81 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 Gene3D G3DSA:3.50.30.10 4 231 3.1E-81 T 12-10-2018 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 3 537 6.1E-219 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 Pfam PF05524 PEP-utilising enzyme, N-terminal 3 124 3.9E-34 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 223 5.9E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 NPD12_3596 ec1bdeb3cc465da5ee1906c438eafd4e 538 SUPERFAMILY SSF51621 247 537 6.28E-112 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 NPD12_862 fa243f3afc4582235c95cecedda332a6 329 Gene3D G3DSA:3.40.50.1980 37 182 1.5E-27 T 12-10-2018 NPD12_862 fa243f3afc4582235c95cecedda332a6 329 Gene3D G3DSA:3.40.50.1980 183 329 1.9E-21 T 12-10-2018 NPD12_862 fa243f3afc4582235c95cecedda332a6 329 SUPERFAMILY SSF53807 51 311 2.35E-49 T 12-10-2018 NPD12_862 fa243f3afc4582235c95cecedda332a6 329 Pfam PF01497 Periplasmic binding protein 70 306 9.0E-30 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_50 9f0c91e23d0bbbd4a5c4693592bfb824 348 SUPERFAMILY SSF102114 14 297 1.33E-58 T 12-10-2018 NPD12_50 9f0c91e23d0bbbd4a5c4693592bfb824 348 SMART SM00729 52 259 3.2E-29 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_50 9f0c91e23d0bbbd4a5c4693592bfb824 348 Gene3D G3DSA:3.20.20.70 1 344 4.4E-123 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_50 9f0c91e23d0bbbd4a5c4693592bfb824 348 Pfam PF04055 Radical SAM superfamily 56 214 3.2E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_50 9f0c91e23d0bbbd4a5c4693592bfb824 348 SMART SM00876 227 320 0.0043 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_50 9f0c91e23d0bbbd4a5c4693592bfb824 348 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 4 341 4.4E-169 T 12-10-2018 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM NPD12_50 9f0c91e23d0bbbd4a5c4693592bfb824 348 PIRSF PIRSF004762 1 329 8.7E-72 T 12-10-2018 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 Gene3D G3DSA:1.20.20.10 1 78 7.7E-28 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 Pfam PF00137 ATP synthase subunit C 13 75 7.3E-18 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 ProSitePatterns PS00605 ATP synthase c subunit signature. 41 62 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 77 1.2E-20 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 PRINTS PR00124 ATP synthase C subunit signature 13 32 2.0E-24 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 PRINTS PR00124 ATP synthase C subunit signature 51 76 2.0E-24 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 PRINTS PR00124 ATP synthase C subunit signature 34 49 2.0E-24 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 76 15.741 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_306 d22f9ce81c627341bace1f4eb7ded38b 79 SUPERFAMILY SSF81333 6 78 8.24E-21 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 7.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 Gene3D G3DSA:3.40.50.720 3 248 1.3E-94 T 12-10-2018 NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 SUPERFAMILY SSF51735 5 247 1.63E-94 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 6.4E-76 T 12-10-2018 NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.6E-53 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.6E-53 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.6E-53 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.6E-53 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.6E-53 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.6E-53 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 192 2.5E-6 T 12-10-2018 NPD12_69 fb18260c33ffdc5eada0ddf3c23cde72 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 246 2.6E-105 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 NPD12_1849 6402b6c9905a6ce89c62f73d60dbe565 111 SUPERFAMILY SSF102705 5 109 4.32E-16 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily NPD12_1849 6402b6c9905a6ce89c62f73d60dbe565 111 Gene3D G3DSA:3.30.70.120 2 109 2.2E-30 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal NPD12_1849 6402b6c9905a6ce89c62f73d60dbe565 111 Pfam PF03091 CutA1 divalent ion tolerance protein 63 106 3.7E-5 T 12-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 Gene3D G3DSA:1.10.1670.10 12 203 1.1E-79 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 SUPERFAMILY SSF48150 4 209 7.85E-73 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 Pfam PF00633 Helix-hairpin-helix motif 100 127 7.8E-8 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 PIRSF PIRSF001435 2 212 4.3E-61 T 12-10-2018 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 Hamap MF_00942 Endonuclease III [nth]. 1 209 38.958 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 SMART SM00478 38 185 1.9E-59 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 Gene3D G3DSA:1.10.340.30 21 132 1.1E-79 T 12-10-2018 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 SMART SM00525 186 206 0.0068 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 TIGRFAM TIGR01083 nth: endonuclease III 5 194 8.8E-84 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 3.9E-21 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 NPD12_367 ceb927ac057872393826e0d22662a1aa 213 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 1.1E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 Gene3D G3DSA:1.10.560.10 7 519 3.0E-229 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 7.7E-252 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.015 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.5E-104 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 Gene3D G3DSA:3.50.7.10 190 371 3.0E-229 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 SUPERFAMILY SSF54849 136 206 3.2E-26 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 PRINTS PR00298 60kDa chaperonin signature 82 109 1.7E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 PRINTS PR00298 60kDa chaperonin signature 396 417 1.7E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 PRINTS PR00298 60kDa chaperonin signature 348 373 1.7E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 PRINTS PR00298 60kDa chaperonin signature 266 289 1.7E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 PRINTS PR00298 60kDa chaperonin signature 26 52 1.7E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 SUPERFAMILY SSF48592 6 519 1.08E-77 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 Gene3D G3DSA:3.30.260.10 136 408 3.0E-229 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily NPD12_3426 f38b6b35e7b06f4605eaf552e8b6d1fb 541 SUPERFAMILY SSF52029 183 374 3.89E-82 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily NPD12_3326 a895ecfbbf70c595d3ab1b3ed8d6931e 232 Pfam PF04055 Radical SAM superfamily 21 176 9.0E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3326 a895ecfbbf70c595d3ab1b3ed8d6931e 232 Gene3D G3DSA:3.20.20.70 1 232 3.4E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3326 a895ecfbbf70c595d3ab1b3ed8d6931e 232 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 3 230 3.6E-93 T 12-10-2018 IPR012838 Pyruvate formate-lyase 1 activating enzyme GO:0043365|GO:0055114 NPD12_3326 a895ecfbbf70c595d3ab1b3ed8d6931e 232 ProSitePatterns PS01087 Radical activating enzymes signature. 15 36 - T 12-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 NPD12_3326 a895ecfbbf70c595d3ab1b3ed8d6931e 232 SUPERFAMILY SSF102114 21 207 3.1E-27 T 12-10-2018 NPD12_3326 a895ecfbbf70c595d3ab1b3ed8d6931e 232 Pfam PF13353 4Fe-4S single cluster domain 13 131 4.0E-23 T 12-10-2018 NPD12_876 9fc6456b5b14de1596a1078db265ec78 325 Gene3D G3DSA:3.30.930.10 1 239 1.1E-78 T 12-10-2018 NPD12_876 9fc6456b5b14de1596a1078db265ec78 325 SUPERFAMILY SSF82649 241 325 9.94E-26 T 12-10-2018 NPD12_876 9fc6456b5b14de1596a1078db265ec78 325 Gene3D G3DSA:3.30.390.50 240 325 4.0E-28 T 12-10-2018 NPD12_876 9fc6456b5b14de1596a1078db265ec78 325 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 3 319 2.2E-101 T 12-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 NPD12_876 9fc6456b5b14de1596a1078db265ec78 325 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 241 324 1.0E-26 T 12-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 NPD12_876 9fc6456b5b14de1596a1078db265ec78 325 SUPERFAMILY SSF55681 1 239 2.49E-74 T 12-10-2018 NPD12_876 9fc6456b5b14de1596a1078db265ec78 325 Pfam PF03099 Biotin/lipoate A/B protein ligase family 44 149 1.5E-13 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 NPD12_3003 233a384fbd8014e281091e37534d933c 114 PRINTS PR00332 Histidine triad family signature 5 21 2.0E-19 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_3003 233a384fbd8014e281091e37534d933c 114 PRINTS PR00332 Histidine triad family signature 26 44 2.0E-19 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_3003 233a384fbd8014e281091e37534d933c 114 PRINTS PR00332 Histidine triad family signature 94 104 2.0E-19 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_3003 233a384fbd8014e281091e37534d933c 114 SUPERFAMILY SSF54197 1 113 2.55E-41 T 12-10-2018 IPR036265 HIT-like superfamily NPD12_3003 233a384fbd8014e281091e37534d933c 114 Pfam PF01230 HIT domain 11 108 4.2E-30 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_3003 233a384fbd8014e281091e37534d933c 114 ProSitePatterns PS00892 HIT domain signature. 87 105 - T 12-10-2018 IPR019808 Histidine triad, conserved site NPD12_3003 233a384fbd8014e281091e37534d933c 114 Gene3D G3DSA:3.30.428.10 1 114 8.3E-46 T 12-10-2018 IPR036265 HIT-like superfamily NPD12_1502 f3e4435e999a34f678563f11949d2a86 222 SMART SM00257 173 222 1.4E-6 T 12-10-2018 IPR018392 LysM domain NPD12_1502 f3e4435e999a34f678563f11949d2a86 222 SUPERFAMILY SSF54106 171 222 3.66E-8 T 12-10-2018 NPD12_1502 f3e4435e999a34f678563f11949d2a86 222 Pfam PF01476 LysM domain 174 222 5.0E-11 T 12-10-2018 IPR018392 LysM domain NPD12_1502 f3e4435e999a34f678563f11949d2a86 222 Gene3D G3DSA:3.10.350.10 172 220 4.6E-15 T 12-10-2018 IPR036779 LysM domain superfamily NPD12_3280 29546738d084bfbeedad54516c079b18 342 Pfam PF13379 NMT1-like family 44 267 2.8E-25 T 12-10-2018 NPD12_3280 29546738d084bfbeedad54516c079b18 342 Gene3D G3DSA:3.40.190.10 120 223 6.9E-50 T 12-10-2018 NPD12_3280 29546738d084bfbeedad54516c079b18 342 Gene3D G3DSA:3.40.190.10 45 318 6.9E-50 T 12-10-2018 NPD12_3280 29546738d084bfbeedad54516c079b18 342 SUPERFAMILY SSF53850 44 263 5.26E-38 T 12-10-2018 NPD12_3393 2a48f39df8ef5b8ae15512fd33f0e547 520 Gene3D G3DSA:3.10.105.10 285 489 4.5E-73 T 12-10-2018 NPD12_3393 2a48f39df8ef5b8ae15512fd33f0e547 520 Gene3D G3DSA:3.90.76.10 66 187 4.5E-73 T 12-10-2018 NPD12_3393 2a48f39df8ef5b8ae15512fd33f0e547 520 Gene3D G3DSA:3.40.190.10 54 500 4.5E-73 T 12-10-2018 NPD12_3393 2a48f39df8ef5b8ae15512fd33f0e547 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 446 4.1E-51 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain NPD12_3393 2a48f39df8ef5b8ae15512fd33f0e547 520 SUPERFAMILY SSF53850 36 516 4.52E-68 T 12-10-2018 NPD12_3393 2a48f39df8ef5b8ae15512fd33f0e547 520 PIRSF PIRSF002741 1 516 1.0E-55 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 NPD12_128 d049458c24854fe95170b35251752e6a 445 Gene3D G3DSA:3.30.300.180 2 83 8.9E-22 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily NPD12_128 d049458c24854fe95170b35251752e6a 445 ProSitePatterns PS01008 DnaA protein signature. 402 421 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 NPD12_128 d049458c24854fe95170b35251752e6a 445 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 442 8.4E-185 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 NPD12_128 d049458c24854fe95170b35251752e6a 445 SMART SM00760 352 421 9.8E-46 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 NPD12_128 d049458c24854fe95170b35251752e6a 445 Pfam PF11638 DnaA N-terminal domain 7 67 1.1E-13 T 12-10-2018 IPR024633 DnaA N-terminal domain NPD12_128 d049458c24854fe95170b35251752e6a 445 Gene3D G3DSA:3.40.50.300 89 272 3.5E-55 T 12-10-2018 NPD12_128 d049458c24854fe95170b35251752e6a 445 Gene3D G3DSA:1.10.8.60 274 342 4.6E-31 T 12-10-2018 NPD12_128 d049458c24854fe95170b35251752e6a 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 141 161 6.0E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like NPD12_128 d049458c24854fe95170b35251752e6a 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 266 6.0E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like NPD12_128 d049458c24854fe95170b35251752e6a 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 402 421 6.0E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like NPD12_128 d049458c24854fe95170b35251752e6a 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 205 219 6.0E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like NPD12_128 d049458c24854fe95170b35251752e6a 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 173 187 6.0E-53 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like NPD12_128 d049458c24854fe95170b35251752e6a 445 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 443 35.012 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 NPD12_128 d049458c24854fe95170b35251752e6a 445 SUPERFAMILY SSF48295 339 444 2.88E-39 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 NPD12_128 d049458c24854fe95170b35251752e6a 445 SMART SM00382 140 268 7.9E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_128 d049458c24854fe95170b35251752e6a 445 SUPERFAMILY SSF52540 108 320 6.32E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_128 d049458c24854fe95170b35251752e6a 445 Gene3D G3DSA:1.10.1750.10 343 445 2.7E-39 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 NPD12_128 d049458c24854fe95170b35251752e6a 445 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 353 421 2.6E-33 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 NPD12_128 d049458c24854fe95170b35251752e6a 445 Pfam PF00308 Bacterial dnaA protein 108 325 8.1E-104 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 SUPERFAMILY SSF51430 6 266 1.1E-90 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 Gene3D G3DSA:3.20.20.100 1 281 2.3E-113 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 PIRSF PIRSF000097 1 272 1.0E-89 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 PRINTS PR00069 Aldo-keto reductase signature 93 111 2.7E-52 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 PRINTS PR00069 Aldo-keto reductase signature 131 148 2.7E-52 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 PRINTS PR00069 Aldo-keto reductase signature 165 194 2.7E-52 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.7E-52 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 PRINTS PR00069 Aldo-keto reductase signature 202 226 2.7E-52 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 Pfam PF00248 Aldo/keto reductase family 16 267 1.5E-47 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain NPD12_3514 d4929717281c72f06c0f7237b65c3857 281 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 131 148 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:3.90.1100.10 18 153 4.5E-51 T 12-10-2018 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:3.90.1100.10 411 600 1.6E-75 T 12-10-2018 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 ProSitePatterns PS01166 RNA polymerases beta chain signature. 935 947 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:2.40.270.10 994 1060 8.7E-27 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:3.90.1110.10 154 262 1.9E-7 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Pfam PF04563 RNA polymerase beta subunit 26 475 6.4E-29 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Pfam PF10385 RNA polymerase beta subunit external 1 domain 567 634 3.1E-22 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:3.90.1100.10 625 691 9.6E-20 T 12-10-2018 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:3.90.1800.10 1070 1122 2.6E-10 T 12-10-2018 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:2.40.50.150 804 943 1.1E-63 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 294 1.6E-24 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Pfam PF04561 RNA polymerase Rpb2, domain 2 363 430 8.9E-5 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1160 12.545 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:2.40.50.100 694 764 4.8E-27 T 12-10-2018 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 SUPERFAMILY SSF64484 12 1168 0.0 T 12-10-2018 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Pfam PF00562 RNA polymerase Rpb2, domain 6 696 1082 9.0E-164 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 214 909 1.1E-302 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Pfam PF04565 RNA polymerase Rpb2, domain 3 489 557 2.8E-31 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Pfam PF04560 RNA polymerase Rpb2, domain 7 1084 1158 2.7E-27 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_3647 41aca682b18dfd5cb62365879105c429 1232 Gene3D G3DSA:2.40.270.10 765 803 1.7E-5 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_2377 b042013a6a6c2901a011714497dfd252 145 Pfam PF13673 Acetyltransferase (GNAT) domain 47 140 1.0E-15 T 12-10-2018 IPR000182 GNAT domain NPD12_2377 b042013a6a6c2901a011714497dfd252 145 Gene3D G3DSA:3.40.630.30 1 139 2.4E-25 T 12-10-2018 NPD12_2377 b042013a6a6c2901a011714497dfd252 145 SUPERFAMILY SSF55729 1 140 3.49E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_3499 5ab59659529a53513077ff80977735b4 361 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 359 1.8E-143 T 12-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic NPD12_3499 5ab59659529a53513077ff80977735b4 361 Gene3D G3DSA:3.20.20.70 1 242 1.3E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3499 5ab59659529a53513077ff80977735b4 361 SUPERFAMILY SSF51445 1 243 4.42E-91 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_3499 5ab59659529a53513077ff80977735b4 361 Gene3D G3DSA:2.40.100.10 243 360 7.3E-42 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily NPD12_3499 5ab59659529a53513077ff80977735b4 361 SUPERFAMILY SSF50891 246 359 1.02E-37 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 SUPERFAMILY SSF88659 175 256 2.06E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 SUPERFAMILY SSF88946 5 110 1.23E-35 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 Gene3D G3DSA:1.10.601.10 11 113 4.2E-29 T 12-10-2018 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 9.5E-154 T 12-10-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 Pfam PF04545 Sigma-70, region 4 206 255 3.4E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 PIRSF PIRSF000770 11 257 5.0E-36 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 36 256 2.7E-83 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 SUPERFAMILY SSF88659 114 189 7.41E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 Pfam PF04539 Sigma-70 region 3 124 176 2.5E-7 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 Pfam PF04542 Sigma-70 region 2 42 111 1.6E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 Gene3D G3DSA:1.20.140.160 114 257 2.9E-28 T 12-10-2018 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 PRINTS PR00046 Major sigma-70 factor signature 242 253 2.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 PRINTS PR00046 Major sigma-70 factor signature 210 222 2.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 PRINTS PR00046 Major sigma-70 factor signature 227 242 2.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 PRINTS PR00046 Major sigma-70 factor signature 90 98 2.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 PRINTS PR00046 Major sigma-70 factor signature 66 79 2.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2579 16819af41019ae9df5e9f3769bdd5e16 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 256 3.3E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_2573 f0eb701a0260e5dcda50cbc2311179bb 290 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 12 286 4.7E-83 T 12-10-2018 IPR011862 Phosphate binding protein GO:0042301 NPD12_2573 f0eb701a0260e5dcda50cbc2311179bb 290 Gene3D G3DSA:3.40.190.10 47 285 6.2E-84 T 12-10-2018 NPD12_2573 f0eb701a0260e5dcda50cbc2311179bb 290 Pfam PF12849 PBP superfamily domain 37 273 3.6E-40 T 12-10-2018 IPR024370 PBP domain NPD12_2573 f0eb701a0260e5dcda50cbc2311179bb 290 SUPERFAMILY SSF53850 44 287 1.97E-69 T 12-10-2018 NPD12_2573 f0eb701a0260e5dcda50cbc2311179bb 290 Gene3D G3DSA:3.40.190.10 120 243 6.2E-84 T 12-10-2018 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 496 4.2E-50 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 PIRSF PIRSF039088 1 503 5.8E-257 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 Gene3D G3DSA:2.40.30.20 1 92 4.2E-35 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 501 52.036 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 SUPERFAMILY SSF47917 372 500 8.89E-47 T 12-10-2018 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 Gene3D G3DSA:3.40.50.300 94 371 1.9E-127 T 12-10-2018 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 SUPERFAMILY SSF50615 10 94 1.14E-29 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 500 5.3E-255 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 5.4E-73 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 Gene3D G3DSA:1.20.150.20 372 502 2.5E-51 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 SUPERFAMILY SSF52540 96 370 2.29E-101 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_309 9e34e40ec26ef8af75178f67d12ecccb 504 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 91 1.5E-17 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_1883 d5108a4ca8c77a337bfc6abd965f4569 295 PIRSF PIRSF006816 1 262 7.3E-64 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 NPD12_1883 d5108a4ca8c77a337bfc6abd965f4569 295 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 220 256 1.5E-12 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain NPD12_1883 d5108a4ca8c77a337bfc6abd965f4569 295 SUPERFAMILY SSF63380 2 91 5.53E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel NPD12_1883 d5108a4ca8c77a337bfc6abd965f4569 295 Gene3D G3DSA:3.40.50.80 107 210 1.5E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_1883 d5108a4ca8c77a337bfc6abd965f4569 295 Gene3D G3DSA:2.40.30.10 1 91 6.0E-24 T 12-10-2018 NPD12_1883 d5108a4ca8c77a337bfc6abd965f4569 295 SUPERFAMILY SSF52343 104 255 5.37E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Gene3D G3DSA:3.10.580.10 70 293 7.9E-79 T 12-10-2018 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 SMART SM00116 77 125 12.0 T 12-10-2018 IPR000644 CBS domain NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 SMART SM00116 256 304 3.8E-4 T 12-10-2018 IPR000644 CBS domain NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 SUPERFAMILY SSF75138 139 252 3.14E-28 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 SUPERFAMILY SSF54631 68 300 1.1E-25 T 12-10-2018 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Pfam PF07085 DRTGG domain 142 244 6.2E-25 T 12-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Gene3D G3DSA:3.10.310.20 426 546 1.6E-34 T 12-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 SMART SM01131 417 544 4.2E-50 T 12-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 SUPERFAMILY SSF64182 3 543 8.48E-69 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Gene3D G3DSA:3.90.1640.10 294 425 6.1E-47 T 12-10-2018 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Pfam PF00571 CBS domain 251 300 1.5E-7 T 12-10-2018 IPR000644 CBS domain NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Pfam PF00571 CBS domain 70 120 1.4E-4 T 12-10-2018 IPR000644 CBS domain NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Pfam PF02833 DHHA2 domain 419 543 4.3E-18 T 12-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Pfam PF01368 DHH family 5 382 3.9E-28 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_2685 a8387fdf9a55cbf4adfc00d209b5259b 547 Gene3D G3DSA:3.40.1390.20 130 245 7.9E-79 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily NPD12_2767 195916838c5cd1a0d51ca036aac3628b 129 PIRSF PIRSF039090 1 129 4.4E-44 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 NPD12_2767 195916838c5cd1a0d51ca036aac3628b 129 Gene3D G3DSA:1.20.120.340 1 123 7.2E-42 T 12-10-2018 NPD12_2767 195916838c5cd1a0d51ca036aac3628b 129 SUPERFAMILY SSF101116 5 123 5.23E-39 T 12-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 NPD12_2767 195916838c5cd1a0d51ca036aac3628b 129 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 121 6.3E-32 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 NPD12_2767 195916838c5cd1a0d51ca036aac3628b 129 Pfam PF02561 Flagellar protein FliS 7 120 1.7E-41 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 SUPERFAMILY SSF52402 72 267 8.37E-56 T 12-10-2018 NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 SUPERFAMILY SSF54862 16 58 5.3E-5 T 12-10-2018 NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 PIRSF PIRSF000089 71 397 1.0E-100 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 SUPERFAMILY SSF52467 273 391 6.35E-44 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 Gene3D G3DSA:3.40.50.620 70 270 4.4E-72 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 SMART SM00893 74 260 4.0E-43 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 Pfam PF01012 Electron transfer flavoprotein domain 76 248 1.0E-43 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 Gene3D G3DSA:3.40.50.1220 271 398 6.8E-50 T 12-10-2018 NPD12_1198 ef37af6c51dc422eef1ec00adaa9a152 400 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 274 355 1.8E-31 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 NPD12_3062 458b2793f0f46d2cbef3c7e5bf454de1 808 Pfam PF05272 Virulence-associated protein E 480 676 1.9E-57 T 12-10-2018 IPR007936 Virulence-associated E NPD12_2413 2ae96c37ac0d49134ea37072443f647a 78 Pfam PF01381 Helix-turn-helix 5 52 1.6E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2413 2ae96c37ac0d49134ea37072443f647a 78 SUPERFAMILY SSF47413 3 66 1.26E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_2413 2ae96c37ac0d49134ea37072443f647a 78 Gene3D G3DSA:1.10.260.40 1 65 1.2E-23 T 12-10-2018 NPD12_2413 2ae96c37ac0d49134ea37072443f647a 78 SMART SM00530 4 59 3.8E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1318 9c789e8e25d8a67d5311fcfc655da457 357 PIRSF PIRSF000524 1 356 8.7E-92 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 NPD12_1318 9c789e8e25d8a67d5311fcfc655da457 357 Gene3D G3DSA:3.90.1150.10 5 353 8.1E-114 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1318 9c789e8e25d8a67d5311fcfc655da457 357 Pfam PF00266 Aminotransferase class-V 23 321 2.9E-30 T 12-10-2018 IPR000192 Aminotransferase class V domain NPD12_1318 9c789e8e25d8a67d5311fcfc655da457 357 Gene3D G3DSA:3.40.640.10 14 257 8.1E-114 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1318 9c789e8e25d8a67d5311fcfc655da457 357 SUPERFAMILY SSF53383 4 355 1.65E-86 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2537 920f0b92222419121e6b71b22651c884 584 Gene3D G3DSA:1.10.8.60 447 523 5.6E-23 T 12-10-2018 NPD12_2537 920f0b92222419121e6b71b22651c884 584 Pfam PF02954 Bacterial regulatory protein, Fis family 542 581 1.2E-13 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_2537 920f0b92222419121e6b71b22651c884 584 Gene3D G3DSA:3.10.580.10 8 135 1.2E-22 T 12-10-2018 NPD12_2537 920f0b92222419121e6b71b22651c884 584 Gene3D G3DSA:3.30.450.20 137 259 3.0E-15 T 12-10-2018 NPD12_2537 920f0b92222419121e6b71b22651c884 584 SMART SM00382 295 447 6.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 SMART SM00091 137 203 8.5E-7 T 12-10-2018 IPR000014 PAS domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 Pfam PF00158 Sigma-54 interaction domain 275 442 4.9E-65 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_2537 920f0b92222419121e6b71b22651c884 584 SUPERFAMILY SSF46689 488 583 2.82E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2537 920f0b92222419121e6b71b22651c884 584 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 547 564 5.4E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_2537 920f0b92222419121e6b71b22651c884 584 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 564 584 5.4E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_2537 920f0b92222419121e6b71b22651c884 584 SUPERFAMILY SSF55785 133 232 3.32E-12 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_2537 920f0b92222419121e6b71b22651c884 584 Pfam PF13426 PAS domain 148 240 3.1E-10 T 12-10-2018 IPR000014 PAS domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 241 4.3E-8 T 12-10-2018 IPR000014 PAS domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 SUPERFAMILY SSF54631 9 135 4.3E-23 T 12-10-2018 NPD12_2537 920f0b92222419121e6b71b22651c884 584 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 299 312 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_2537 920f0b92222419121e6b71b22651c884 584 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 361 376 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_2537 920f0b92222419121e6b71b22651c884 584 SMART SM00116 18 66 3.8 T 12-10-2018 IPR000644 CBS domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 SMART SM00116 82 129 1.4E-7 T 12-10-2018 IPR000644 CBS domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 Gene3D G3DSA:1.10.10.60 524 584 9.9E-16 T 12-10-2018 NPD12_2537 920f0b92222419121e6b71b22651c884 584 Pfam PF00571 CBS domain 80 124 3.3E-7 T 12-10-2018 IPR000644 CBS domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 Pfam PF00571 CBS domain 11 63 1.2E-5 T 12-10-2018 IPR000644 CBS domain NPD12_2537 920f0b92222419121e6b71b22651c884 584 SUPERFAMILY SSF52540 275 518 4.11E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2537 920f0b92222419121e6b71b22651c884 584 Gene3D G3DSA:3.40.50.300 260 446 1.7E-63 T 12-10-2018 NPD12_1703 311019ad69ee7df00879d2f25f2e88c3 142 SUPERFAMILY SSF89447 1 131 2.99E-51 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily NPD12_1703 311019ad69ee7df00879d2f25f2e88c3 142 Gene3D G3DSA:2.40.330.20 1 141 5.2E-55 T 12-10-2018 IPR038619 MraZ superfamily NPD12_1703 311019ad69ee7df00879d2f25f2e88c3 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 140 3.2E-49 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 NPD12_1703 311019ad69ee7df00879d2f25f2e88c3 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 54.311 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 NPD12_1703 311019ad69ee7df00879d2f25f2e88c3 142 Pfam PF02381 MraZ protein, putative antitoxin-like 72 129 4.7E-18 T 12-10-2018 IPR020603 MraZ domain NPD12_1703 311019ad69ee7df00879d2f25f2e88c3 142 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 2.7E-20 T 12-10-2018 IPR020603 MraZ domain NPD12_1703 311019ad69ee7df00879d2f25f2e88c3 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 137 2.0E-60 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 NPD12_2467 525b3b9ec2688f02eeaf4d0d7356506e 104 SUPERFAMILY SSF55315 3 99 9.82E-22 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_2467 525b3b9ec2688f02eeaf4d0d7356506e 104 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 94 4.7E-15 T 12-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 NPD12_2467 525b3b9ec2688f02eeaf4d0d7356506e 104 Gene3D G3DSA:3.30.1330.30 2 100 2.4E-27 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_1385 e0307214898f572f28b2908bdae47aff 458 Gene3D G3DSA:1.20.1250.20 14 223 2.9E-12 T 12-10-2018 NPD12_1385 e0307214898f572f28b2908bdae47aff 458 Gene3D G3DSA:1.20.1250.20 241 448 3.5E-12 T 12-10-2018 NPD12_1385 e0307214898f572f28b2908bdae47aff 458 SUPERFAMILY SSF103473 23 427 7.06E-36 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_1385 e0307214898f572f28b2908bdae47aff 458 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 22 456 1.8E-116 T 12-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 NPD12_1385 e0307214898f572f28b2908bdae47aff 458 Pfam PF13347 MFS/sugar transport protein 24 444 1.5E-102 T 12-10-2018 NPD12_801 a04fbda51fbc6a44de54b616a9961dfe 183 SUPERFAMILY SSF47413 2 70 1.35E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_801 a04fbda51fbc6a44de54b616a9961dfe 183 Pfam PF07883 Cupin domain 126 175 1.0E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel NPD12_801 a04fbda51fbc6a44de54b616a9961dfe 183 Gene3D G3DSA:2.60.120.10 90 183 3.0E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_801 a04fbda51fbc6a44de54b616a9961dfe 183 Gene3D G3DSA:1.10.260.40 1 73 6.6E-20 T 12-10-2018 NPD12_801 a04fbda51fbc6a44de54b616a9961dfe 183 SMART SM00530 10 65 1.9E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_801 a04fbda51fbc6a44de54b616a9961dfe 183 Pfam PF01381 Helix-turn-helix 11 63 5.1E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_801 a04fbda51fbc6a44de54b616a9961dfe 183 SUPERFAMILY SSF51182 58 182 7.6E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 Gene3D G3DSA:3.40.50.620 1 329 1.5E-144 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 5.7E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 5.7E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 5.7E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 5.7E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 5.7E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 476 2.9E-162 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 SUPERFAMILY SSF52374 4 314 2.95E-112 T 12-10-2018 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 321 4.7E-106 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 478 31.757 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 Gene3D G3DSA:1.10.10.350 376 485 1.5E-29 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1288 8e6ee26e13cfd6525287ddd8f27bda7e 485 SUPERFAMILY SSF48163 315 478 2.75E-35 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 342 3.4E-29 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 134 2.0E-28 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 Pfam PF01926 50S ribosome-binding GTPase 178 296 8.4E-27 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 Pfam PF01926 50S ribosome-binding GTPase 6 121 4.0E-29 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 Gene3D G3DSA:3.40.50.300 1 164 1.6E-47 T 12-10-2018 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 434 3.2E-181 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 354 434 2.2E-35 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 SUPERFAMILY SSF52540 6 166 2.66E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 PIRSF PIRSF006485 2 439 1.9E-182 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 SMART SM00382 175 320 2.9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 SMART SM00382 2 167 0.0032 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 2.2E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 74 92 2.2E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 Gene3D G3DSA:3.30.300.20 354 437 1.4E-34 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 Hamap MF_00195 GTPase Der [der]. 3 437 40.891 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 Gene3D G3DSA:3.40.50.300 171 352 5.8E-55 T 12-10-2018 NPD12_2567 24103ccb2086bb1caa59b6bbcf4f2153 439 SUPERFAMILY SSF52540 140 438 2.26E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1187 ecb1fccfdcd9282d6956e34433c9861a 181 Gene3D G3DSA:3.60.21.10 1 180 1.3E-67 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like NPD12_1187 ecb1fccfdcd9282d6956e34433c9861a 181 SUPERFAMILY SSF56300 1 172 2.62E-39 T 12-10-2018 NPD12_1187 ecb1fccfdcd9282d6956e34433c9861a 181 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 164 3.9E-31 T 12-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 NPD12_1187 ecb1fccfdcd9282d6956e34433c9861a 181 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 160 8.4E-25 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 NPD12_536 b3b8ba4db238b88fefe693229a82fb17 192 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 1 191 25.143 T 12-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 NPD12_536 b3b8ba4db238b88fefe693229a82fb17 192 PIRSF PIRSF006102 1 192 5.8E-57 T 12-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 NPD12_536 b3b8ba4db238b88fefe693229a82fb17 192 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 1 190 8.2E-81 T 12-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 NPD12_536 b3b8ba4db238b88fefe693229a82fb17 192 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 190 1.0E-61 T 12-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 623 9.2E-225 T 12-10-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 478 602 2.1E-50 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 Gene3D G3DSA:2.70.70.10 466 625 8.0E-56 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 SUPERFAMILY SSF51261 474 623 2.27E-53 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 480 599 4.6E-43 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 541 553 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 Gene3D G3DSA:3.30.1360.60 1 77 9.8E-31 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 SUPERFAMILY SSF55604 6 80 9.81E-24 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 Pfam PF02378 Phosphotransferase system, EIIC 108 383 3.0E-33 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_1061 f14e17a5db713ec7e30c66c4f8f99048 625 Pfam PF00367 phosphotransferase system, EIIB 9 41 4.7E-17 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 Pfam PF02734 DAK2 domain 401 582 1.8E-49 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 SUPERFAMILY SSF82549 1 331 3.66E-121 T 12-10-2018 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 SUPERFAMILY SSF101473 360 583 1.1E-45 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 Gene3D G3DSA:3.30.1180.20 183 332 4.0E-49 T 12-10-2018 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 Gene3D G3DSA:3.40.50.10440 13 182 2.7E-66 T 12-10-2018 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 Gene3D G3DSA:1.25.40.340 369 586 3.0E-54 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 Pfam PF02733 Dak1 domain 18 328 1.7E-127 T 12-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 3.2E-136 T 12-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 SMART SM01120 400 583 6.2E-60 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_1164 46df83ac2d294945260b80355bf2eda4 586 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 378 581 6.4E-42 T 12-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 NPD12_3315 3e1331e231ac1a1c82c4a33e21fc5eb1 365 SUPERFAMILY SSF82771 13 95 2.88E-21 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_3315 3e1331e231ac1a1c82c4a33e21fc5eb1 365 Gene3D G3DSA:3.40.1440.10 1 99 1.1E-29 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_3315 3e1331e231ac1a1c82c4a33e21fc5eb1 365 SMART SM00465 13 95 2.8E-17 T 12-10-2018 IPR000305 GIY-YIG endonuclease NPD12_3315 3e1331e231ac1a1c82c4a33e21fc5eb1 365 Pfam PF02151 UvrB/uvrC motif 199 227 1.8E-4 T 12-10-2018 IPR001943 UVR domain GO:0005515 NPD12_3315 3e1331e231ac1a1c82c4a33e21fc5eb1 365 Pfam PF01541 GIY-YIG catalytic domain 15 90 7.6E-9 T 12-10-2018 IPR000305 GIY-YIG endonuclease NPD12_3315 3e1331e231ac1a1c82c4a33e21fc5eb1 365 SUPERFAMILY SSF46600 186 234 1.7E-5 T 12-10-2018 IPR036876 UVR domain superfamily NPD12_590 1768b273ead981c704511eed21f8f926 241 PIRSF PIRSF039085 1 241 9.9E-115 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 NPD12_590 1768b273ead981c704511eed21f8f926 241 SUPERFAMILY SSF52540 1 236 1.09E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_590 1768b273ead981c704511eed21f8f926 241 Pfam PF00005 ABC transporter 18 166 2.7E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_590 1768b273ead981c704511eed21f8f926 241 SMART SM00382 26 214 2.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_590 1768b273ead981c704511eed21f8f926 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_590 1768b273ead981c704511eed21f8f926 241 Gene3D G3DSA:3.40.50.300 1 241 1.1E-76 T 12-10-2018 NPD12_2994 64887ef923c599316b0494233a67b258 296 Gene3D G3DSA:3.40.50.300 2 181 4.9E-51 T 12-10-2018 NPD12_2994 64887ef923c599316b0494233a67b258 296 TIGRFAM TIGR00436 era: GTP-binding protein Era 5 275 1.6E-100 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2994 64887ef923c599316b0494233a67b258 296 SUPERFAMILY SSF54814 177 293 3.6E-41 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 NPD12_2994 64887ef923c599316b0494233a67b258 296 Hamap MF_00367 GTPase Era [era]. 2 292 37.792 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2994 64887ef923c599316b0494233a67b258 296 Gene3D G3DSA:3.30.300.20 182 296 3.6E-42 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_2994 64887ef923c599316b0494233a67b258 296 Pfam PF07650 KH domain 204 281 2.7E-19 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_2994 64887ef923c599316b0494233a67b258 296 Pfam PF01926 50S ribosome-binding GTPase 7 121 2.6E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_2994 64887ef923c599316b0494233a67b258 296 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 164 8.3E-34 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_2994 64887ef923c599316b0494233a67b258 296 SUPERFAMILY SSF52540 7 197 1.58E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3081 b9c379958108073d640bbced06ed29df 462 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 462 212.044 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 NPD12_3081 b9c379958108073d640bbced06ed29df 462 Pfam PF12390 Selenocysteine synthase N terminal 7 46 4.8E-7 T 12-10-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 NPD12_3081 b9c379958108073d640bbced06ed29df 462 Gene3D G3DSA:3.40.640.10 93 356 1.3E-179 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_3081 b9c379958108073d640bbced06ed29df 462 Pfam PF03841 L-seryl-tRNA selenium transferase 81 445 2.3E-164 T 12-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 NPD12_3081 b9c379958108073d640bbced06ed29df 462 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 7 458 2.9E-198 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 NPD12_3081 b9c379958108073d640bbced06ed29df 462 SUPERFAMILY SSF53383 78 462 7.22E-51 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_3081 b9c379958108073d640bbced06ed29df 462 Gene3D G3DSA:3.90.1150.110 10 450 1.3E-179 T 12-10-2018 NPD12_2797 e7d127a9b006c523fc9706f44eaba049 593 Pfam PF01368 DHH family 78 218 6.6E-12 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_2797 e7d127a9b006c523fc9706f44eaba049 593 Gene3D G3DSA:3.10.310.30 331 453 9.0E-32 T 12-10-2018 NPD12_2797 e7d127a9b006c523fc9706f44eaba049 593 Gene3D G3DSA:3.90.1640.30 53 330 4.9E-96 T 12-10-2018 NPD12_2797 e7d127a9b006c523fc9706f44eaba049 593 SUPERFAMILY SSF64182 53 457 5.23E-113 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily NPD12_2797 e7d127a9b006c523fc9706f44eaba049 593 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 24 546 8.1E-161 T 12-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 NPD12_2797 e7d127a9b006c523fc9706f44eaba049 593 Pfam PF02272 DHHA1 domain 321 448 1.8E-18 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 NPD12_634 ff1fa121fafc3c21d9e6b03603c93b30 174 Gene3D G3DSA:1.10.1760.20 5 171 1.3E-21 T 12-10-2018 NPD12_634 ff1fa121fafc3c21d9e6b03603c93b30 174 Pfam PF12822 ECF transporter, substrate-specific component 7 162 3.4E-14 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 NPD12_347 fa9e77d26105784c81a6a727287b8953 199 Gene3D G3DSA:1.25.40.10 92 168 1.4E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_347 fa9e77d26105784c81a6a727287b8953 199 SMART SM00271 1 62 3.6E-22 T 12-10-2018 IPR001623 DnaJ domain NPD12_347 fa9e77d26105784c81a6a727287b8953 199 SUPERFAMILY SSF46565 1 78 2.49E-22 T 12-10-2018 IPR036869 Chaperone J-domain superfamily NPD12_347 fa9e77d26105784c81a6a727287b8953 199 Gene3D G3DSA:1.10.287.110 1 91 8.4E-22 T 12-10-2018 IPR036869 Chaperone J-domain superfamily NPD12_347 fa9e77d26105784c81a6a727287b8953 199 PRINTS PR00625 DnaJ domain signature 22 37 4.1E-16 T 12-10-2018 IPR001623 DnaJ domain NPD12_347 fa9e77d26105784c81a6a727287b8953 199 PRINTS PR00625 DnaJ domain signature 42 62 4.1E-16 T 12-10-2018 IPR001623 DnaJ domain NPD12_347 fa9e77d26105784c81a6a727287b8953 199 PRINTS PR00625 DnaJ domain signature 4 22 4.1E-16 T 12-10-2018 IPR001623 DnaJ domain NPD12_347 fa9e77d26105784c81a6a727287b8953 199 Pfam PF00226 DnaJ domain 2 67 2.9E-19 T 12-10-2018 IPR001623 DnaJ domain NPD12_347 fa9e77d26105784c81a6a727287b8953 199 SUPERFAMILY SSF48452 102 150 5.24E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_2705 78ee19c0cc5791a0cb7b9a1d979adf10 139 Pfam PF12611 Putative flagellar 115 138 3.1E-13 T 12-10-2018 IPR013367 Flagellar, putative NPD12_2705 78ee19c0cc5791a0cb7b9a1d979adf10 139 TIGRFAM TIGR02530 flg_new: flagellar operon protein 34 139 1.4E-33 T 12-10-2018 IPR013367 Flagellar, putative NPD12_1235 9e7294449e3e0860f0e672aaba7228d0 228 Pfam PF08713 DNA alkylation repair enzyme 6 207 2.2E-13 T 12-10-2018 IPR014825 DNA alkylation repair enzyme NPD12_1235 9e7294449e3e0860f0e672aaba7228d0 228 Gene3D G3DSA:1.25.10.90 1 223 1.7E-16 T 12-10-2018 NPD12_1235 9e7294449e3e0860f0e672aaba7228d0 228 SUPERFAMILY SSF48371 9 208 1.19E-40 T 12-10-2018 IPR016024 Armadillo-type fold NPD12_1943 ee21a5bec361d3a52d0b3f503f403b81 326 Gene3D G3DSA:1.10.443.10 134 325 1.2E-52 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 NPD12_1943 ee21a5bec361d3a52d0b3f503f403b81 326 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 17 50 1.7E-5 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 NPD12_1943 ee21a5bec361d3a52d0b3f503f403b81 326 Gene3D G3DSA:1.10.150.130 14 128 8.6E-19 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal NPD12_1943 ee21a5bec361d3a52d0b3f503f403b81 326 SUPERFAMILY SSF56349 15 318 3.53E-51 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 NPD12_1943 ee21a5bec361d3a52d0b3f503f403b81 326 Pfam PF00589 Phage integrase family 142 310 4.0E-41 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 NPD12_37 e874754efa66c9e4b46adba64f2c5d0a 261 Gene3D G3DSA:3.60.15.10 5 245 4.9E-42 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_37 e874754efa66c9e4b46adba64f2c5d0a 261 SUPERFAMILY SSF56281 2 251 4.19E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_37 e874754efa66c9e4b46adba64f2c5d0a 261 Pfam PF12706 Beta-lactamase superfamily domain 23 201 2.3E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_37 e874754efa66c9e4b46adba64f2c5d0a 261 SMART SM00849 11 190 1.5E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 Pfam PF06071 Protein of unknown function (DUF933) 281 364 1.2E-38 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 PIRSF PIRSF006641 1 365 1.5E-161 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 Pfam PF01926 50S ribosome-binding GTPase 3 113 1.9E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 365 4.0E-157 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 SUPERFAMILY SSF52540 1 303 4.35E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 Gene3D G3DSA:3.10.20.30 46 363 1.4E-161 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 SUPERFAMILY SSF81271 281 362 1.05E-34 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 68 83 8.4E-37 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 8.4E-37 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 103 8.4E-37 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 8.4E-37 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 365 44.673 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 Gene3D G3DSA:1.10.150.300 111 198 1.4E-161 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 NPD12_1702 2f60a6031d8e6b5637f6dfe6423213d5 365 Gene3D G3DSA:3.40.50.300 1 280 1.4E-161 T 12-10-2018 NPD12_241 a1ee5bbaa54bc5efb52e1ab89658e8f1 353 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 352 3.6E-34 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 NPD12_241 a1ee5bbaa54bc5efb52e1ab89658e8f1 353 Gene3D G3DSA:2.40.30.170 47 278 8.4E-43 T 12-10-2018 NPD12_241 a1ee5bbaa54bc5efb52e1ab89658e8f1 353 Gene3D G3DSA:2.40.50.100 58 196 8.4E-43 T 12-10-2018 NPD12_241 a1ee5bbaa54bc5efb52e1ab89658e8f1 353 Gene3D G3DSA:1.10.287.470 91 160 8.4E-43 T 12-10-2018 NPD12_241 a1ee5bbaa54bc5efb52e1ab89658e8f1 353 SUPERFAMILY SSF111369 68 233 5.36E-9 T 12-10-2018 NPD12_241 a1ee5bbaa54bc5efb52e1ab89658e8f1 353 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 67 238 3.2E-13 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain NPD12_241 a1ee5bbaa54bc5efb52e1ab89658e8f1 353 Gene3D G3DSA:2.40.420.20 42 337 8.4E-43 T 12-10-2018 NPD12_2692 5ca8258739614e874d48fdceebf38001 219 Gene3D G3DSA:2.40.10.220 95 213 4.0E-10 T 12-10-2018 NPD12_2692 5ca8258739614e874d48fdceebf38001 219 SUPERFAMILY SSF141371 131 214 1.63E-8 T 12-10-2018 NPD12_2692 5ca8258739614e874d48fdceebf38001 219 Pfam PF12945 Flagellar protein YcgR 8 87 1.6E-18 T 12-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal NPD12_2692 5ca8258739614e874d48fdceebf38001 219 Pfam PF07238 PilZ domain 94 210 7.8E-16 T 12-10-2018 IPR009875 PilZ domain GO:0035438 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 SUPERFAMILY SSF63520 172 275 1.96E-24 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 Gene3D G3DSA:1.10.1790.10 168 278 3.7E-33 T 12-10-2018 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 Gene3D G3DSA:2.30.24.10 1 54 2.1E-20 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 SUPERFAMILY SSF50151 1 51 1.1E-16 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 Pfam PF03123 CAT RNA binding domain 1 54 1.2E-20 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 Pfam PF00874 PRD domain 76 163 2.8E-23 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 Pfam PF00874 PRD domain 181 274 1.3E-18 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 SMART SM01061 1 59 1.8E-25 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 Gene3D G3DSA:1.10.1790.10 64 167 1.4E-35 T 12-10-2018 NPD12_832 e5c85450213aaf31bc599d4b27390f19 279 SUPERFAMILY SSF63520 57 166 5.62E-30 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_1833 5d155b7c3e832cd974eaa2a79738c0fc 148 Pfam PF01844 HNH endonuclease 56 101 8.7E-11 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 NPD12_1833 5d155b7c3e832cd974eaa2a79738c0fc 148 Gene3D G3DSA:3.30.40.60 25 123 5.5E-8 T 12-10-2018 NPD12_1833 5d155b7c3e832cd974eaa2a79738c0fc 148 SMART SM00507 43 97 3.2E-12 T 12-10-2018 IPR003615 HNH nuclease NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 630 658 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 Gene3D G3DSA:1.20.1090.10 643 859 4.8E-68 T 12-10-2018 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 718 738 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 Pfam PF00465 Iron-containing alcohol dehydrogenase 455 847 7.7E-117 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 Pfam PF00171 Aldehyde dehydrogenase family 5 398 3.5E-23 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 Gene3D G3DSA:3.40.309.10 216 402 2.5E-176 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 SUPERFAMILY SSF53720 6 451 6.41E-78 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 SUPERFAMILY SSF56796 446 858 1.7E-125 T 12-10-2018 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 PIRSF PIRSF000111 1 862 0.0 T 12-10-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 Gene3D G3DSA:3.40.605.10 13 443 2.5E-176 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 NPD12_509 aea0c8a625ed04e0f8d43c35e64137b6 862 Gene3D G3DSA:3.40.50.1970 448 641 2.2E-58 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 SUPERFAMILY SSF81660 331 511 1.73E-52 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 52 868 2.2E-212 T 12-10-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 70 9.6E-22 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 Gene3D G3DSA:3.40.50.1000 321 654 0.0 T 12-10-2018 IPR023214 HAD superfamily NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 1.1E-42 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 518 1.1E-42 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 1.1E-42 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 628 1.1E-42 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 645 1.1E-42 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 1.1E-42 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 Gene3D G3DSA:2.70.150.10 14 227 0.0 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 SMART SM00831 1 75 3.5E-29 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 Gene3D G3DSA:1.20.1110.10 53 865 0.0 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 11 864 1.9E-161 T 12-10-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 Pfam PF00122 E1-E2 ATPase 110 303 1.7E-53 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 SUPERFAMILY SSF81665 2 870 3.01E-139 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 Pfam PF00689 Cation transporting ATPase, C-terminus 693 866 2.2E-50 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 215 351 2.8E-28 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 176 1.5E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 580 693 1.3E-36 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 SUPERFAMILY SSF81653 113 224 1.83E-30 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 Pfam PF00702 haloacid dehalogenase-like hydrolase 320 623 1.1E-21 T 12-10-2018 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 666 5.7E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 5.7E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 467 485 5.7E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 609 625 5.7E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 Gene3D G3DSA:3.40.1110.10 334 514 0.0 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_707 c46898b71617c73500c766525054cf83 872 SUPERFAMILY SSF56784 322 713 3.46E-62 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_707 c46898b71617c73500c766525054cf83 872 TIGRFAM TIGR01522 ATPase-IIA2_Ca: calcium-transporting P-type ATPase, PMR1-type 7 871 5.8E-243 T 12-10-2018 IPR006413 P-type ATPase, subfamily IIA, PMR1-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-936837 NPD12_101 825063406fbfc258a40522a5dc98bd88 147 Gene3D G3DSA:3.10.430.100 60 147 2.0E-27 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily NPD12_101 825063406fbfc258a40522a5dc98bd88 147 SUPERFAMILY SSF55653 57 146 3.66E-24 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily NPD12_101 825063406fbfc258a40522a5dc98bd88 147 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 4.7E-24 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_101 825063406fbfc258a40522a5dc98bd88 147 SUPERFAMILY SSF55658 1 56 1.5E-18 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal NPD12_101 825063406fbfc258a40522a5dc98bd88 147 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 26.293 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_101 825063406fbfc258a40522a5dc98bd88 147 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_101 825063406fbfc258a40522a5dc98bd88 147 Gene3D G3DSA:3.40.5.10 1 59 2.2E-24 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_101 825063406fbfc258a40522a5dc98bd88 147 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.1E-42 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_101 825063406fbfc258a40522a5dc98bd88 147 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 145 9.7E-27 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal NPD12_1156 c89743474eddb39015275d93560d4e4d 230 SUPERFAMILY SSF56784 2 227 2.25E-45 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1156 c89743474eddb39015275d93560d4e4d 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 5.0E-28 T 12-10-2018 NPD12_1156 c89743474eddb39015275d93560d4e4d 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 2.4E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1156 c89743474eddb39015275d93560d4e4d 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 189 202 2.4E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1156 c89743474eddb39015275d93560d4e4d 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 2.4E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1156 c89743474eddb39015275d93560d4e4d 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.4E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1156 c89743474eddb39015275d93560d4e4d 230 Gene3D G3DSA:1.10.150.240 16 100 8.7E-71 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 NPD12_1156 c89743474eddb39015275d93560d4e4d 230 Gene3D G3DSA:3.40.50.1000 5 223 8.7E-71 T 12-10-2018 IPR023214 HAD superfamily NPD12_1156 c89743474eddb39015275d93560d4e4d 230 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 225 3.1E-70 T 12-10-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 NPD12_1156 c89743474eddb39015275d93560d4e4d 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 90 194 1.6E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Pfam PF07517 SecA DEAD-like domain 5 382 2.7E-130 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Gene3D G3DSA:1.10.3060.10 571 774 0.0 T 12-10-2018 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 2.6E-232 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 SMART SM00957 4 382 1.4E-276 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 781 19.9 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 ProSitePatterns PS01312 SecA family signature. 480 495 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Pfam PF01043 SecA preprotein cross-linking domain 230 338 8.7E-41 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Pfam PF07516 SecA Wing and Scaffold domain 568 778 8.9E-67 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 SUPERFAMILY SSF52540 397 569 1.08E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 SUPERFAMILY SSF52540 2 395 2.76E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 SMART SM00958 226 338 1.5E-65 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Gene3D G3DSA:1.10.1200.230 621 705 0.0 T 12-10-2018 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Gene3D G3DSA:3.40.50.300 397 570 0.0 T 12-10-2018 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 12-10-2018 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Gene3D G3DSA:3.10.450.50 775 835 1.1E-9 T 12-10-2018 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Pfam PF02810 SEC-C motif 815 833 6.9E-9 T 12-10-2018 IPR004027 SEC-C motif NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 SUPERFAMILY SSF81767 225 348 1.57E-45 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 SUPERFAMILY SSF81886 571 823 2.62E-78 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 Gene3D G3DSA:3.40.50.300 14 396 0.0 T 12-10-2018 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 PRINTS PR00906 SecA protein signature 99 113 1.6E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 PRINTS PR00906 SecA protein signature 393 406 1.6E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 PRINTS PR00906 SecA protein signature 61 85 1.6E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 PRINTS PR00906 SecA protein signature 168 188 1.6E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 PRINTS PR00906 SecA protein signature 115 125 1.6E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 PRINTS PR00906 SecA protein signature 356 373 1.6E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_331 3c688f6352639388dfb233f0ee34bd41 835 PRINTS PR00906 SecA protein signature 319 341 1.6E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 NPD12_3155 54727b81b647730d18b696e4f4be6db5 495 PIRSF PIRSF016636 1 495 7.1E-140 T 12-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB NPD12_3155 54727b81b647730d18b696e4f4be6db5 495 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 158 358 4.3E-26 T 12-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT NPD12_3155 54727b81b647730d18b696e4f4be6db5 495 PIRSF PIRSF500217 1 495 1.5E-143 T 12-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Gene3D G3DSA:3.40.50.300 3 176 3.9E-36 T 12-10-2018 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Pfam PF00929 Exonuclease 496 652 2.6E-26 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Gene3D G3DSA:3.40.50.300 191 317 6.1E-27 T 12-10-2018 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Gene3D G3DSA:3.30.420.10 486 663 1.7E-40 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Gene3D G3DSA:3.40.50.300 349 452 9.8E-20 T 12-10-2018 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 SUPERFAMILY SSF52540 5 850 1.87E-96 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 488 688 2.1E-27 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 SUPERFAMILY SSF53098 494 720 1.01E-46 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 SMART SM00479 494 662 1.2E-28 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 288 5.8E-50 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Gene3D G3DSA:3.40.50.300 684 852 9.3E-20 T 12-10-2018 NPD12_1582 2d1a5021c9408baf963098d6f2464f5e 855 Pfam PF13361 UvrD-like helicase C-terminal domain 295 831 2.3E-102 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 NPD12_3607 5b0c94ed2f3ccf09d448492a8c844a60 288 Pfam PF00005 ABC transporter 24 173 8.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3607 5b0c94ed2f3ccf09d448492a8c844a60 288 SMART SM00382 32 222 3.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3607 5b0c94ed2f3ccf09d448492a8c844a60 288 Gene3D G3DSA:3.40.50.300 1 286 6.8E-84 T 12-10-2018 NPD12_3607 5b0c94ed2f3ccf09d448492a8c844a60 288 SUPERFAMILY SSF52540 3 236 6.69E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3607 5b0c94ed2f3ccf09d448492a8c844a60 288 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 278 2.2E-123 T 12-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 NPD12_3607 5b0c94ed2f3ccf09d448492a8c844a60 288 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 TIGRFAM TIGR02911 sulfite_red_B: sulfite reductase, subunit B 5 265 2.0E-150 T 12-10-2018 IPR014260 Sulphite reductase, subunit B NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 PIRSF PIRSF006816 6 264 2.5E-74 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 PRINTS PR00406 Cytochrome B5 reductase signature 83 97 1.5E-6 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 PRINTS PR00406 Cytochrome B5 reductase signature 145 156 1.5E-6 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 PRINTS PR00406 Cytochrome B5 reductase signature 107 126 1.5E-6 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 PRINTS PR00406 Cytochrome B5 reductase signature 196 204 1.5E-6 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 Pfam PF00175 Oxidoreductase NAD-binding domain 109 209 2.1E-14 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 Gene3D G3DSA:3.40.50.80 95 225 2.8E-22 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 SUPERFAMILY SSF52343 91 257 4.58E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 Gene3D G3DSA:2.40.30.10 8 94 2.8E-9 T 12-10-2018 NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 228 257 1.2E-6 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain NPD12_1144 08043ccf790ac9667c455f4f8acfa0b3 265 SUPERFAMILY SSF63380 7 96 2.87E-17 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel NPD12_886 986704f7fd5a023eda58fb0f8775698f 195 SUPERFAMILY SSF52218 1 185 4.34E-33 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_886 986704f7fd5a023eda58fb0f8775698f 195 Pfam PF03358 NADPH-dependent FMN reductase 1 107 5.1E-23 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_886 986704f7fd5a023eda58fb0f8775698f 195 Gene3D G3DSA:3.40.50.360 1 185 1.4E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Gene3D G3DSA:1.10.10.2290 248 326 4.1E-57 T 12-10-2018 NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Gene3D G3DSA:3.30.160.610 93 182 6.8E-30 T 12-10-2018 NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Gene3D G3DSA:3.30.360.90 364 436 6.4E-26 T 12-10-2018 NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 93 180 9.5E-16 T 12-10-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 311 436 1.0E-22 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 181 328 5.1E-33 T 12-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Gene3D G3DSA:3.40.50.11790 188 354 4.1E-57 T 12-10-2018 NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Gene3D G3DSA:3.30.1490.360 26 92 6.1E-24 T 12-10-2018 NPD12_3042 29c8da7f1aaa4a5a4bf32fd385624331 436 Pfam PF17482 Phage tail sheath C-terminal domain 335 435 2.3E-24 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain NPD12_2882 e13002de105088d75d1526fb39dd6d1e 238 SMART SM00882 4 217 1.0E-64 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 NPD12_2882 e13002de105088d75d1526fb39dd6d1e 238 SUPERFAMILY SSF100950 3 233 4.72E-73 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_2882 e13002de105088d75d1526fb39dd6d1e 238 Gene3D G3DSA:3.40.1080.10 1 219 8.6E-76 T 12-10-2018 NPD12_2882 e13002de105088d75d1526fb39dd6d1e 238 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 4 216 3.2E-58 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 NPD12_2882 e13002de105088d75d1526fb39dd6d1e 238 Pfam PF01144 Coenzyme A transferase 5 216 2.2E-57 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 Gene3D G3DSA:3.10.290.10 1 60 6.5E-20 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 SUPERFAMILY SSF55174 1 91 9.92E-17 T 12-10-2018 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 SMART SM00363 3 62 8.3E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 Pfam PF01479 S4 domain 3 45 2.3E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 SUPERFAMILY SSF55120 61 231 1.76E-45 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 Pfam PF00849 RNA pseudouridylate synthase 65 195 1.7E-19 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 69 227 2.6E-49 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 Gene3D G3DSA:3.30.70.580 65 230 4.8E-55 T 12-10-2018 NPD12_1963 bf4b6732c6a2c33eea220e8e41be653a 236 Gene3D G3DSA:3.30.70.1560 130 213 4.8E-55 T 12-10-2018 NPD12_2438 eb39d3c6e966c0a9052e0b73814479b0 226 SUPERFAMILY SSF52172 1 181 6.97E-42 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2438 eb39d3c6e966c0a9052e0b73814479b0 226 Gene3D G3DSA:3.40.50.2300 1 117 4.7E-38 T 12-10-2018 NPD12_2438 eb39d3c6e966c0a9052e0b73814479b0 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 3.7E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2438 eb39d3c6e966c0a9052e0b73814479b0 226 Gene3D G3DSA:1.10.10.10 118 226 4.0E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2438 eb39d3c6e966c0a9052e0b73814479b0 226 SMART SM00862 148 223 4.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2438 eb39d3c6e966c0a9052e0b73814479b0 226 SMART SM00448 2 112 2.1E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2438 eb39d3c6e966c0a9052e0b73814479b0 226 Pfam PF00072 Response regulator receiver domain 4 113 1.6E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2344 a78b4096e9865bde07a3ccd836fa24c7 118 Gene3D G3DSA:3.30.420.130 1 104 2.3E-27 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily NPD12_2344 a78b4096e9865bde07a3ccd836fa24c7 118 SUPERFAMILY SSF53146 1 116 9.16E-33 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily NPD12_2344 a78b4096e9865bde07a3ccd836fa24c7 118 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 8 96 2.2E-20 T 12-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 SUPERFAMILY SSF54713 152 305 8.9E-51 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 SUPERFAMILY SSF46934 2 53 2.52E-20 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 SUPERFAMILY SSF54713 54 147 1.57E-19 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 Gene3D G3DSA:3.30.479.20 55 151 6.6E-28 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 Pfam PF00889 Elongation factor TS 71 286 6.3E-70 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 Gene3D G3DSA:3.30.479.20 152 285 1.5E-49 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 Gene3D G3DSA:1.10.8.10 1 54 1.1E-26 T 12-10-2018 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 Hamap MF_00050 Elongation factor Ts [tsf]. 1 303 75.636 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 Gene3D G3DSA:1.10.286.20 200 244 1.5E-49 T 12-10-2018 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 ProSitePatterns PS01126 Elongation factor Ts signature 1. 10 25 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_2482 991e5aec78647db79dc596d13f4e66d8 307 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 2 304 9.5E-96 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Gene3D G3DSA:1.10.1420.10 398 534 5.3E-105 T 12-10-2018 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 SUPERFAMILY SSF48334 264 565 7.59E-92 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Pfam PF05192 MutS domain III 266 558 1.5E-45 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 3 920 25.355 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 SUPERFAMILY SSF52540 566 801 4.87E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Gene3D G3DSA:1.10.1420.10 263 558 5.3E-105 T 12-10-2018 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 PIRSF PIRSF037677 844 930 47.0 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 PIRSF PIRSF037677 1 846 7.8E-179 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Pfam PF00488 MutS domain V 611 800 1.2E-87 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Gene3D G3DSA:3.40.1170.10 1 117 4.6E-46 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Pfam PF05188 MutS domain II 124 249 6.9E-12 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 SMART SM00533 281 590 8.2E-106 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 SUPERFAMILY SSF53150 113 277 9.94E-31 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Gene3D G3DSA:3.40.50.300 567 886 7.2E-105 T 12-10-2018 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Pfam PF01624 MutS domain I 4 115 3.1E-43 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 SMART SM00534 608 797 7.1E-124 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 689 705 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Gene3D G3DSA:3.30.420.110 123 257 1.3E-19 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 Pfam PF05190 MutS family domain IV 426 517 4.9E-31 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 3 817 4.8E-303 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 NPD12_1950 488db16c70d0ada155b9c21fc701f806 932 SUPERFAMILY SSF55271 2 111 7.19E-41 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 5 183 2.6E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 178 9.6E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 8.6E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 8.6E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 8.6E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 8.6E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 SUPERFAMILY SSF56784 1 187 4.14E-49 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 Gene3D G3DSA:3.40.50.1000 5 188 7.9E-51 T 12-10-2018 IPR023214 HAD superfamily NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 1.5E-43 T 12-10-2018 NPD12_3570 8a8e4b7b08953883ffe8d9d57f5f0f74 215 Gene3D G3DSA:1.10.150.240 16 84 7.9E-51 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 NPD12_551 06b60021e139db73c70880d9df5c09ad 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 272 9.6E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_551 06b60021e139db73c70880d9df5c09ad 276 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 13 274 1.1E-64 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 NPD12_551 06b60021e139db73c70880d9df5c09ad 276 Gene3D G3DSA:1.10.3720.10 58 276 1.6E-30 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_551 06b60021e139db73c70880d9df5c09ad 276 SUPERFAMILY SSF161098 14 266 8.88E-33 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1802 c6190b6c292eeb21100be17271ea3266 312 SUPERFAMILY SSF100950 63 311 1.5E-72 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_1802 c6190b6c292eeb21100be17271ea3266 312 Gene3D G3DSA:3.40.50.1360 52 311 1.2E-83 T 12-10-2018 NPD12_1802 c6190b6c292eeb21100be17271ea3266 312 Pfam PF04198 Putative sugar-binding domain 61 310 1.1E-71 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 NPD12_1802 c6190b6c292eeb21100be17271ea3266 312 Gene3D G3DSA:1.10.10.60 3 51 1.6E-18 T 12-10-2018 NPD12_1802 c6190b6c292eeb21100be17271ea3266 312 SUPERFAMILY SSF88659 12 46 1.05E-6 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2385 7a5ee6f9413ccb20f8881a05fa34cb87 465 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 237 458 2.1E-45 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 NPD12_2385 7a5ee6f9413ccb20f8881a05fa34cb87 465 Pfam PF00854 POT family 85 202 1.6E-14 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_2385 7a5ee6f9413ccb20f8881a05fa34cb87 465 Pfam PF00854 POT family 237 426 1.1E-31 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_2385 7a5ee6f9413ccb20f8881a05fa34cb87 465 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 147 159 - T 12-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 NPD12_2385 7a5ee6f9413ccb20f8881a05fa34cb87 465 Gene3D G3DSA:1.20.1250.20 238 464 8.7E-54 T 12-10-2018 NPD12_2385 7a5ee6f9413ccb20f8881a05fa34cb87 465 Gene3D G3DSA:1.20.1250.20 1 237 1.2E-46 T 12-10-2018 NPD12_2385 7a5ee6f9413ccb20f8881a05fa34cb87 465 SUPERFAMILY SSF103473 12 453 2.35E-37 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 SUPERFAMILY SSF53328 6 209 1.96E-62 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 Gene3D G3DSA:3.40.50.170 2 208 3.4E-75 T 12-10-2018 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 4 306 35.071 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 Pfam PF00551 Formyl transferase 10 182 2.3E-40 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 Pfam PF02911 Formyl transferase, C-terminal domain 207 303 1.5E-29 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 303 6.7E-96 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 Gene3D G3DSA:3.10.25.10 209 313 1.2E-33 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 NPD12_2556 18d7624accd0eff266d4faa7c1e95b04 313 SUPERFAMILY SSF50486 207 311 2.35E-31 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 SUPERFAMILY SSF54631 71 208 3.54E-23 T 12-10-2018 NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 Pfam PF00571 CBS domain 80 132 3.3E-5 T 12-10-2018 IPR000644 CBS domain NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 Pfam PF00571 CBS domain 146 205 9.5E-5 T 12-10-2018 IPR000644 CBS domain NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 SUPERFAMILY SSF46785 5 81 4.22E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 PIRSF PIRSF026546 4 213 1.1E-94 T 12-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 Pfam PF08279 HTH domain 9 61 7.4E-11 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 SMART SM00116 86 133 0.68 T 12-10-2018 IPR000644 CBS domain NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 SMART SM00116 152 207 0.0038 T 12-10-2018 IPR000644 CBS domain NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 Gene3D G3DSA:3.10.580.10 64 213 6.3E-48 T 12-10-2018 NPD12_2991 305982d35c87902ac95ecfc2c6b3002e 213 Gene3D G3DSA:1.10.10.10 1 63 5.4E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_25 6c640563c2acb19e51e4f38106609026 310 Pfam PF16199 Radical_SAM C-terminal domain 214 298 1.9E-27 T 12-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 NPD12_25 6c640563c2acb19e51e4f38106609026 310 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 10 308 4.6E-118 T 12-10-2018 IPR005911 Protein YhcC-like GO:0051536 NPD12_25 6c640563c2acb19e51e4f38106609026 310 SMART SM00729 26 253 5.4E-41 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_25 6c640563c2acb19e51e4f38106609026 310 Pfam PF04055 Radical SAM superfamily 46 208 7.9E-17 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_25 6c640563c2acb19e51e4f38106609026 310 SUPERFAMILY SSF102114 10 296 1.28E-51 T 12-10-2018 NPD12_25 6c640563c2acb19e51e4f38106609026 310 Gene3D G3DSA:3.80.30.20 44 241 4.3E-18 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 Pfam PF00579 tRNA synthetases class I (W and Y) 35 322 2.0E-75 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 56 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 Gene3D G3DSA:3.40.50.620 4 221 1.2E-71 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 Gene3D G3DSA:3.10.290.10 328 397 4.0E-19 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 SUPERFAMILY SSF55174 313 396 4.06E-18 T 12-10-2018 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 SMART SM00363 341 400 7.0E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 Pfam PF01479 S4 domain 343 385 6.0E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 SUPERFAMILY SSF52374 5 321 5.91E-87 T 12-10-2018 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 398 45.358 T 12-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 396 7.2E-118 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 Gene3D G3DSA:1.10.240.10 224 327 8.7E-24 T 12-10-2018 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 165 180 2.5E-24 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 2.5E-24 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 2.5E-24 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_1390 2fa7108207098ec6cab0478a298e5d42 400 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 2.5E-24 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_1211 a88a73e30ca8cd093a0da0df34902880 185 Gene3D G3DSA:3.40.50.360 53 184 5.2E-22 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1211 a88a73e30ca8cd093a0da0df34902880 185 Pfam PF12724 Flavodoxin domain 61 156 5.0E-10 T 12-10-2018 IPR026816 Flavodoxin domain NPD12_1211 a88a73e30ca8cd093a0da0df34902880 185 SUPERFAMILY SSF52218 52 183 6.22E-21 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 SUPERFAMILY SSF90123 15 328 3.27E-46 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 Gene3D G3DSA:1.20.1560.10 13 320 5.2E-38 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 Gene3D G3DSA:3.40.50.300 329 571 5.2E-91 T 12-10-2018 NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 Pfam PF00005 ABC transporter 349 498 4.1E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 SMART SM00382 358 550 2.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 Pfam PF00664 ABC transporter transmembrane region 56 287 3.8E-16 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 SUPERFAMILY SSF52540 328 569 2.33E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1243 5da7b29273893f35dcaffb27a4f2e039 571 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1353 1b2463d7c02898b1b1cfc1b5b3442805 545 Gene3D G3DSA:1.10.20.110 48 417 1.1E-224 T 12-10-2018 NPD12_1353 1b2463d7c02898b1b1cfc1b5b3442805 545 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 18 539 4.1E-271 T 12-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 NPD12_1353 1b2463d7c02898b1b1cfc1b5b3442805 545 Gene3D G3DSA:3.40.640.10 170 395 1.1E-224 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1353 1b2463d7c02898b1b1cfc1b5b3442805 545 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 325 338 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 NPD12_1353 1b2463d7c02898b1b1cfc1b5b3442805 545 Pfam PF00155 Aminotransferase class I and II 165 521 4.6E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1353 1b2463d7c02898b1b1cfc1b5b3442805 545 Gene3D G3DSA:3.90.1150.10 41 537 1.1E-224 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1353 1b2463d7c02898b1b1cfc1b5b3442805 545 SUPERFAMILY SSF53383 94 534 4.32E-42 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 SUPERFAMILY SSF47928 2 105 1.83E-22 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 PRINTS PR00125 ATP synthase delta subunit signature 5 24 2.9E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 PRINTS PR00125 ATP synthase delta subunit signature 150 168 2.9E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 PRINTS PR00125 ATP synthase delta subunit signature 74 85 2.9E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 PRINTS PR00125 ATP synthase delta subunit signature 85 99 2.9E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 PRINTS PR00125 ATP synthase delta subunit signature 135 150 2.9E-23 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 173 4.7E-39 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 Gene3D G3DSA:1.10.520.20 5 96 1.4E-12 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 174 1.0E-46 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 177 19.417 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_308 74928cb04eb1b4ef1a22248146a8ccbc 179 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 12-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_2488 2f1f087f329862d5da1d3962641c845d 123 SUPERFAMILY SSF52980 11 109 2.57E-25 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 NPD12_2488 2f1f087f329862d5da1d3962641c845d 123 Gene3D G3DSA:3.40.1350.10 11 123 1.4E-31 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 NPD12_2488 2f1f087f329862d5da1d3962641c845d 123 Hamap MF_00048 UPF0102 protein YraN [yraN]. 5 116 23.176 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 NPD12_2488 2f1f087f329862d5da1d3962641c845d 123 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 6 119 1.5E-24 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 NPD12_2488 2f1f087f329862d5da1d3962641c845d 123 Pfam PF02021 Uncharacterised protein family UPF0102 12 103 7.8E-29 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 NPD12_906 8a7ca559beb92e9ff2daf6239abb983a 332 Gene3D G3DSA:3.40.47.10 208 332 3.4E-22 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_906 8a7ca559beb92e9ff2daf6239abb983a 332 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 243 332 1.4E-18 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_906 8a7ca559beb92e9ff2daf6239abb983a 332 SUPERFAMILY SSF53901 4 332 2.11E-33 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_906 8a7ca559beb92e9ff2daf6239abb983a 332 Gene3D G3DSA:3.40.47.10 1 194 3.9E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_906 8a7ca559beb92e9ff2daf6239abb983a 332 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 188 1.2E-10 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_1028 ef6ded7d85ff1cb5555fc0309a636909 381 Pfam PF01381 Helix-turn-helix 13 64 2.0E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1028 ef6ded7d85ff1cb5555fc0309a636909 381 Gene3D G3DSA:1.10.260.40 2 68 2.6E-23 T 12-10-2018 NPD12_1028 ef6ded7d85ff1cb5555fc0309a636909 381 SMART SM00530 9 64 1.6E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1028 ef6ded7d85ff1cb5555fc0309a636909 381 SUPERFAMILY SSF47413 5 69 5.63E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3638 8956f7ab82d711ef428093c729c5a726 206 SUPERFAMILY SSF52166 1 205 5.89E-81 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3638 8956f7ab82d711ef428093c729c5a726 206 Pfam PF00573 Ribosomal protein L4/L1 family 18 203 7.9E-72 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 NPD12_3638 8956f7ab82d711ef428093c729c5a726 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 4.3E-81 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3638 8956f7ab82d711ef428093c729c5a726 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 206 36.177 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3638 8956f7ab82d711ef428093c729c5a726 206 Gene3D G3DSA:3.40.1370.10 3 206 1.4E-80 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_807 6eb553c9ba9d4207df56401e8667d927 128 SUPERFAMILY SSF54593 6 122 3.22E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_807 6eb553c9ba9d4207df56401e8667d927 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 119 6.9E-18 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain NPD12_807 6eb553c9ba9d4207df56401e8667d927 128 Gene3D G3DSA:3.10.180.10 2 122 4.9E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 Gene3D G3DSA:1.10.10.10 1 58 3.1E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 Pfam PF00455 DeoR C terminal sensor domain 77 231 1.7E-45 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 SUPERFAMILY SSF100950 75 233 1.26E-25 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 SMART SM00420 6 58 4.3E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 SMART SM01134 73 232 6.3E-58 T 12-10-2018 NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.7E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 SUPERFAMILY SSF46785 4 78 1.66E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1856 9698bbe00dc9b67cc5456dad1f77d48c 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 NPD12_1139 c6995bcd6172748e515a4dba3c8d36c9 279 SUPERFAMILY SSF54211 1 144 5.92E-19 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_1139 c6995bcd6172748e515a4dba3c8d36c9 279 PIRSF PIRSF033887 1 276 2.4E-78 T 12-10-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 NPD12_1139 c6995bcd6172748e515a4dba3c8d36c9 279 Pfam PF00288 GHMP kinases N terminal domain 74 120 6.3E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 NPD12_1139 c6995bcd6172748e515a4dba3c8d36c9 279 Gene3D G3DSA:3.30.230.10 13 134 1.5E-11 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_1178 9bfb7f74f77efda71b9ff2afd5be09e4 236 SMART SM00448 2 112 9.8E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1178 9bfb7f74f77efda71b9ff2afd5be09e4 236 SMART SM00862 157 233 3.3E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1178 9bfb7f74f77efda71b9ff2afd5be09e4 236 Pfam PF00072 Response regulator receiver domain 4 113 2.6E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1178 9bfb7f74f77efda71b9ff2afd5be09e4 236 SUPERFAMILY SSF52172 1 187 7.83E-40 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1178 9bfb7f74f77efda71b9ff2afd5be09e4 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 232 1.8E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1178 9bfb7f74f77efda71b9ff2afd5be09e4 236 Gene3D G3DSA:3.40.50.2300 1 129 3.3E-38 T 12-10-2018 NPD12_1178 9bfb7f74f77efda71b9ff2afd5be09e4 236 Gene3D G3DSA:1.10.10.10 132 236 1.1E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1853 892f4ae90a85ef120b6592278f198925 230 Pfam PF00072 Response regulator receiver domain 6 115 8.0E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1853 892f4ae90a85ef120b6592278f198925 230 SMART SM00448 4 114 6.7E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1853 892f4ae90a85ef120b6592278f198925 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 5.4E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1853 892f4ae90a85ef120b6592278f198925 230 SMART SM00862 152 228 7.7E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1853 892f4ae90a85ef120b6592278f198925 230 SUPERFAMILY SSF46894 129 228 1.5E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_1853 892f4ae90a85ef120b6592278f198925 230 Gene3D G3DSA:1.10.10.10 132 230 3.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1853 892f4ae90a85ef120b6592278f198925 230 Gene3D G3DSA:3.40.50.2300 2 131 3.1E-39 T 12-10-2018 NPD12_1853 892f4ae90a85ef120b6592278f198925 230 SUPERFAMILY SSF52172 4 128 9.53E-42 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 SUPERFAMILY SSF54211 470 638 4.55E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 TIGRFAM TIGR02903 spore_lon_C: ATP-dependent protease, Lon family 28 639 0.0 T 12-10-2018 IPR014252 Sporulation protease LonC NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 SMART SM00382 199 378 5.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 548 556 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 SUPERFAMILY SSF52540 164 443 3.69E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 598 616 1.3E-31 T 12-10-2018 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 470 486 1.3E-31 T 12-10-2018 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 207 226 1.3E-31 T 12-10-2018 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 545 564 1.3E-31 T 12-10-2018 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 575 594 1.3E-31 T 12-10-2018 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 Gene3D G3DSA:3.30.230.10 459 639 9.9E-53 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 442 637 5.5E-34 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 375 9.6E-16 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_100 ebcffd6cf24edd5113609facb035df4d 639 Gene3D G3DSA:3.40.50.300 161 376 6.2E-36 T 12-10-2018 NPD12_1847 27b599a1afeb1f31e7dac3eb202d5bfa 263 Gene3D G3DSA:3.60.10.10 1 263 2.7E-78 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily NPD12_1847 27b599a1afeb1f31e7dac3eb202d5bfa 263 SUPERFAMILY SSF56219 1 261 7.33E-36 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily NPD12_1847 27b599a1afeb1f31e7dac3eb202d5bfa 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 254 1.2E-8 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase NPD12_98 147a7636aceef8273279686b05319a3b 573 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 2.9E-7 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 294 309 2.9E-7 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 227 246 2.9E-7 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 SUPERFAMILY SSF53738 210 316 1.92E-19 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 SUPERFAMILY SSF53738 29 234 5.1E-48 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 Gene3D G3DSA:3.40.120.10 31 187 2.5E-50 T 12-10-2018 NPD12_98 147a7636aceef8273279686b05319a3b 573 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 507 553 1.2E-9 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 SUPERFAMILY SSF55957 441 570 2.09E-15 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 Gene3D G3DSA:3.40.120.10 209 323 2.1E-22 T 12-10-2018 NPD12_98 147a7636aceef8273279686b05319a3b 573 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 322 447 1.1E-19 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 180 2.8E-43 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 313 7.7E-22 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 Gene3D G3DSA:3.30.310.50 467 565 3.3E-10 T 12-10-2018 NPD12_98 147a7636aceef8273279686b05319a3b 573 Gene3D G3DSA:3.40.120.10 324 449 3.1E-35 T 12-10-2018 NPD12_98 147a7636aceef8273279686b05319a3b 573 SUPERFAMILY SSF53738 302 452 1.14E-28 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_98 147a7636aceef8273279686b05319a3b 573 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_552 fd1d911e94c6afa054c3e5e343fd0081 248 SUPERFAMILY SSF52540 3 235 1.94E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_552 fd1d911e94c6afa054c3e5e343fd0081 248 Pfam PF00005 ABC transporter 19 172 4.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_552 fd1d911e94c6afa054c3e5e343fd0081 248 Gene3D G3DSA:3.40.50.300 1 247 5.2E-66 T 12-10-2018 NPD12_552 fd1d911e94c6afa054c3e5e343fd0081 248 SMART SM00382 28 220 8.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_552 fd1d911e94c6afa054c3e5e343fd0081 248 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 19.729 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 Pfam PF01386 Ribosomal L25p family 6 89 3.5E-13 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 Gene3D G3DSA:2.170.120.20 94 186 2.7E-14 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 SUPERFAMILY SSF50715 12 178 1.01E-38 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 Gene3D G3DSA:2.40.240.10 4 92 6.0E-16 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 177 3.0E-15 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 92 4.0E-8 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3329 6bf7c354d7341c5bf4e9113482ea69a6 189 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 14 177 2.9E-30 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3045 7ba31980b5a6933f3380348a100499a3 163 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 13 116 1.5E-28 T 12-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component NPD12_2021 9f0523157b8a57b5a7cd5dc5ccc46fe2 178 PRINTS PR00502 NUDIX hydrolase family signature 85 100 4.8E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_2021 9f0523157b8a57b5a7cd5dc5ccc46fe2 178 PRINTS PR00502 NUDIX hydrolase family signature 71 85 4.8E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_2021 9f0523157b8a57b5a7cd5dc5ccc46fe2 178 SUPERFAMILY SSF55811 6 172 7.58E-48 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 NPD12_2021 9f0523157b8a57b5a7cd5dc5ccc46fe2 178 Gene3D G3DSA:3.90.79.10 4 177 1.4E-52 T 12-10-2018 NPD12_2021 9f0523157b8a57b5a7cd5dc5ccc46fe2 178 Pfam PF00293 NUDIX domain 41 153 4.7E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 NPD12_3569 4c0f39f908732852cbeb8ed4fb83fa5a 225 Gene3D G3DSA:3.20.20.70 1 221 4.5E-79 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3569 4c0f39f908732852cbeb8ed4fb83fa5a 225 SUPERFAMILY SSF51569 1 216 2.2E-69 T 12-10-2018 NPD12_3569 4c0f39f908732852cbeb8ed4fb83fa5a 225 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 NPD12_3569 4c0f39f908732852cbeb8ed4fb83fa5a 225 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 210 1.0E-52 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 NPD12_3569 4c0f39f908732852cbeb8ed4fb83fa5a 225 ProSitePatterns PS00958 Transaldolase active site. 83 100 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 NPD12_940 b936fbf37919af06ad1c01cdd40dfdc5 356 PIRSF PIRSF005508 1 356 1.4E-131 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 NPD12_940 b936fbf37919af06ad1c01cdd40dfdc5 356 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 12 342 1.6E-116 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 NPD12_940 b936fbf37919af06ad1c01cdd40dfdc5 356 Pfam PF01758 Sodium Bile acid symporter family 57 254 5.9E-47 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 NPD12_940 b936fbf37919af06ad1c01cdd40dfdc5 356 Gene3D G3DSA:1.20.1530.20 5 342 4.3E-28 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_3271 18d898a00068c6ccefb509f9c0dca79b 250 SUPERFAMILY SSF88713 20 234 1.29E-63 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_3271 18d898a00068c6ccefb509f9c0dca79b 250 Pfam PF01522 Polysaccharide deacetylase 47 167 2.1E-35 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 NPD12_3271 18d898a00068c6ccefb509f9c0dca79b 250 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 46 234 4.0E-75 T 12-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB NPD12_3271 18d898a00068c6ccefb509f9c0dca79b 250 Gene3D G3DSA:3.20.20.370 24 243 2.1E-69 T 12-10-2018 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 395 2.7E-104 T 12-10-2018 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 Gene3D G3DSA:2.30.40.10 4 393 1.4E-131 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 SUPERFAMILY SSF51338 1 394 1.05E-26 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 Pfam PF01979 Amidohydrolase family 49 392 5.0E-28 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 SUPERFAMILY SSF51556 54 338 6.82E-83 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 Hamap MF_00220_B Dihydroorotase [pyrC]. 4 395 38.216 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 Gene3D G3DSA:3.20.20.140 53 338 1.4E-131 T 12-10-2018 NPD12_3350 990da1081e6254da0c60c00c06a65a3d 396 ProSitePatterns PS00483 Dihydroorotase signature 2. 278 289 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 SUPERFAMILY SSF50129 4 173 1.49E-54 T 12-10-2018 IPR011032 GroES-like superfamily NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 Gene3D G3DSA:3.90.180.10 24 328 7.0E-106 T 12-10-2018 NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 Gene3D G3DSA:3.40.50.720 152 288 7.0E-106 T 12-10-2018 NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 Pfam PF00107 Zinc-binding dehydrogenase 174 293 6.7E-28 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 SUPERFAMILY SSF51735 141 311 2.1E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 132 2.8E-33 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 NPD12_3576 3ea61325b78da642ca95463b8eb75fb4 349 SMART SM00829 11 347 8.5E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 NPD12_1583 3686a52eb2038e68f51b749f3758a491 376 Pfam PF07853 Protein of unknown function (DUF1648) 149 196 1.1E-14 T 12-10-2018 IPR012867 Domain of unknown function DUF1648 NPD12_1583 3686a52eb2038e68f51b749f3758a491 376 PIRSF PIRSF032908 1 373 3.5E-87 T 12-10-2018 IPR014574 Uncharacterised conserved protein UCP032908 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 501 527 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 SUPERFAMILY SSF52467 436 556 1.53E-37 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 SUPERFAMILY SSF56645 7 242 3.53E-86 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 PRINTS PR00163 Rubredoxin signature 586 602 1.1E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 PRINTS PR00163 Rubredoxin signature 616 632 1.1E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 SUPERFAMILY SSF47203 227 380 3.7E-58 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.5E-50 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Pfam PF00301 Rubredoxin 587 632 1.2E-18 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Gene3D G3DSA:2.40.110.10 121 234 2.6E-43 T 12-10-2018 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Gene3D G3DSA:1.20.140.10 235 397 3.4E-55 T 12-10-2018 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 9.2E-37 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Gene3D G3DSA:2.20.28.10 578 635 7.8E-21 T 12-10-2018 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Gene3D G3DSA:3.40.50.1220 434 565 1.3E-43 T 12-10-2018 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.0E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 438 520 8.1E-27 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 ProSitePatterns PS00202 Rubredoxin signature. 616 626 - T 12-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 SUPERFAMILY SSF57802 583 634 1.43E-18 T 12-10-2018 NPD12_2874 c290a8e71156a90bf4f56c135680e76f 635 Gene3D G3DSA:1.10.540.10 2 120 8.4E-40 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 NPD12_389 7ba27de00822153f4e21cf755967fad7 77 Pfam PF03840 Preprotein translocase SecG subunit 6 74 9.5E-20 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 NPD12_389 7ba27de00822153f4e21cf755967fad7 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 6.6E-22 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 NPD12_389 7ba27de00822153f4e21cf755967fad7 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.8E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 NPD12_389 7ba27de00822153f4e21cf755967fad7 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 2.8E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 NPD12_389 7ba27de00822153f4e21cf755967fad7 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 2.8E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 Gene3D G3DSA:3.30.300.160 30 107 5.5E-7 T 12-10-2018 NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 SUPERFAMILY SSF160246 27 106 2.28E-13 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 Gene3D G3DSA:3.30.450.90 110 241 7.2E-43 T 12-10-2018 NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 Gene3D G3DSA:3.40.50.300 243 509 1.8E-104 T 12-10-2018 NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 SUPERFAMILY SSF52540 122 470 3.86E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 Pfam PF00437 Type II/IV secretion system protein 147 409 3.4E-80 T 12-10-2018 IPR001482 Type II/IV secretion system protein NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 337 351 - T 12-10-2018 IPR001482 Type II/IV secretion system protein NPD12_2075 11ca5188fc19d9e0d6597dd68801392c 509 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 27 108 3.1E-15 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 Gene3D G3DSA:3.40.50.720 2 263 4.8E-89 T 12-10-2018 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 PIRSF PIRSF000161 1 265 3.9E-72 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 Gene3D G3DSA:3.30.360.10 127 233 4.8E-89 T 12-10-2018 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 SUPERFAMILY SSF55347 129 234 2.83E-27 T 12-10-2018 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 264 28.727 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 SUPERFAMILY SSF51735 1 265 3.55E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 129 263 4.4E-36 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 264 5.4E-75 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_980 f0ff51d6d00fba3f0a63b276c9da678a 265 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 124 6.7E-36 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_1159 9c69bced0d0e39880a3fd4aae16241e8 229 Gene3D G3DSA:2.60.120.10 17 143 2.4E-19 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1159 9c69bced0d0e39880a3fd4aae16241e8 229 SMART SM00100 10 133 5.3E-4 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_1159 9c69bced0d0e39880a3fd4aae16241e8 229 SUPERFAMILY SSF51206 26 137 8.77E-27 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like NPD12_1159 9c69bced0d0e39880a3fd4aae16241e8 229 SUPERFAMILY SSF46785 153 222 2.29E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1159 9c69bced0d0e39880a3fd4aae16241e8 229 Gene3D G3DSA:1.10.10.10 144 228 1.6E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1159 9c69bced0d0e39880a3fd4aae16241e8 229 Pfam PF00027 Cyclic nucleotide-binding domain 35 116 2.7E-12 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_1159 9c69bced0d0e39880a3fd4aae16241e8 229 Pfam PF13545 Crp-like helix-turn-helix domain 154 220 4.3E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 SUPERFAMILY SSF90123 11 320 3.4E-74 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 Gene3D G3DSA:1.20.1560.10 2 319 6.3E-81 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 Gene3D G3DSA:3.40.50.300 327 574 1.1E-90 T 12-10-2018 NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 SMART SM00382 362 548 4.3E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 SUPERFAMILY SSF52540 328 572 7.59E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 Pfam PF00005 ABC transporter 354 502 1.3E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_478 911c7a527f5afca300fd1e882a5bf0f5 574 Pfam PF00664 ABC transporter transmembrane region 18 290 3.7E-48 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 SUPERFAMILY SSF46785 168 257 4.92E-41 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 Gene3D G3DSA:1.10.10.10 161 258 1.9E-45 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 SUPERFAMILY SSF55781 11 155 5.4E-5 T 12-10-2018 NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 Gene3D G3DSA:3.30.450.40 1 160 4.2E-59 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 258 141.112 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 Pfam PF06018 CodY GAF-like domain 3 179 2.2E-70 T 12-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 4 254 8.0E-114 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 PIRSF PIRSF011572 1 258 4.2E-122 T 12-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 NPD12_2484 a4cf4e9da360bee04cdc9708d1e1bebb 258 Pfam PF08222 CodY helix-turn-helix domain 198 258 2.9E-34 T 12-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal NPD12_1110 32c24e8d212f7a8e98e431dcdd9e4f02 208 Gene3D G3DSA:3.40.50.10230 1 208 3.1E-84 T 12-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 NPD12_1110 32c24e8d212f7a8e98e431dcdd9e4f02 208 SUPERFAMILY SSF63965 10 207 2.62E-72 T 12-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 NPD12_1110 32c24e8d212f7a8e98e431dcdd9e4f02 208 Pfam PF02570 Precorrin-8X methylmutase 10 204 2.8E-79 T 12-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 NPD12_2780 090749bc5be91f6869c1a7741924d36b 199 Pfam PF04509 CheC-like family 104 141 1.0E-10 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 NPD12_2780 090749bc5be91f6869c1a7741924d36b 199 Pfam PF04509 CheC-like family 10 46 7.2E-15 T 12-10-2018 IPR007597 CheC-like protein GO:0016787 NPD12_2780 090749bc5be91f6869c1a7741924d36b 199 SUPERFAMILY SSF103039 4 198 5.23E-57 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_2780 090749bc5be91f6869c1a7741924d36b 199 Gene3D G3DSA:3.40.1550.10 5 199 9.1E-61 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_638 73a1641200f8d6b720f57efcc9b79000 409 SUPERFAMILY SSF56300 1 348 7.77E-54 T 12-10-2018 NPD12_638 73a1641200f8d6b720f57efcc9b79000 409 Pfam PF00149 Calcineurin-like phosphoesterase 1 240 2.5E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 NPD12_638 73a1641200f8d6b720f57efcc9b79000 409 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 269 1.5E-53 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 NPD12_638 73a1641200f8d6b720f57efcc9b79000 409 Gene3D G3DSA:3.60.21.10 1 288 2.6E-73 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like NPD12_638 73a1641200f8d6b720f57efcc9b79000 409 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 301 379 7.0E-6 T 12-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain NPD12_2621 dc74a924c531b3879049074110153a2a 329 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 321 1.2E-79 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 NPD12_2621 dc74a924c531b3879049074110153a2a 329 PIRSF PIRSF001439 1 329 2.0E-83 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 NPD12_2621 dc74a924c531b3879049074110153a2a 329 Gene3D G3DSA:3.30.1780.10 4 324 1.6E-103 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 NPD12_2621 dc74a924c531b3879049074110153a2a 329 Gene3D G3DSA:3.40.50.720 124 302 1.6E-103 T 12-10-2018 NPD12_2621 dc74a924c531b3879049074110153a2a 329 SUPERFAMILY SSF51735 1 328 2.44E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2740 c3524b03a1901886086f2fada58bd7c0 57 Pfam PF09388 Spo0E like sporulation regulatory protein 8 52 3.9E-6 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 NPD12_2740 c3524b03a1901886086f2fada58bd7c0 57 SUPERFAMILY SSF140500 5 54 1.96E-6 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 NPD12_804 fb3d53be5462fb5b20d2f56fc8133165 281 Pfam PF00005 ABC transporter 20 160 4.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_804 fb3d53be5462fb5b20d2f56fc8133165 281 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_804 fb3d53be5462fb5b20d2f56fc8133165 281 SMART SM00382 29 207 1.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_804 fb3d53be5462fb5b20d2f56fc8133165 281 SUPERFAMILY SSF52540 3 219 1.41E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_804 fb3d53be5462fb5b20d2f56fc8133165 281 Gene3D G3DSA:3.40.50.300 1 238 6.3E-68 T 12-10-2018 NPD12_3574 374e90ab93127c5c8062fcf7956d8b50 181 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 4 170 9.5E-81 T 12-10-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 NPD12_3574 374e90ab93127c5c8062fcf7956d8b50 181 PIRSF PIRSF038321 1 181 1.6E-92 T 12-10-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 NPD12_3574 374e90ab93127c5c8062fcf7956d8b50 181 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 179 8.4E-90 T 12-10-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 NPD12_296 a3f756d0c1bc0dcacaba81b351b1533f 351 Gene3D G3DSA:3.40.50.11030 217 351 9.0E-42 T 12-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily NPD12_296 a3f756d0c1bc0dcacaba81b351b1533f 351 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 10 208 5.4E-70 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 NPD12_296 a3f756d0c1bc0dcacaba81b351b1533f 351 Pfam PF01300 Telomere recombination 24 199 2.7E-58 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 NPD12_296 a3f756d0c1bc0dcacaba81b351b1533f 351 PIRSF PIRSF004930 1 350 9.0E-132 T 12-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 NPD12_296 a3f756d0c1bc0dcacaba81b351b1533f 351 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 344 3.9E-27 T 12-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain NPD12_296 a3f756d0c1bc0dcacaba81b351b1533f 351 SUPERFAMILY SSF55821 7 211 5.8E-65 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily NPD12_296 a3f756d0c1bc0dcacaba81b351b1533f 351 Gene3D G3DSA:3.90.870.10 2 214 3.9E-82 T 12-10-2018 NPD12_3106 f8444cd784fe28c8a9dc58e9935d2ff9 163 Pfam PF04093 rod shape-determining protein MreD 5 154 1.8E-19 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 NPD12_3106 f8444cd784fe28c8a9dc58e9935d2ff9 163 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 153 2.0E-27 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 NPD12_3106 f8444cd784fe28c8a9dc58e9935d2ff9 163 PIRSF PIRSF037497 2 163 2.1E-38 T 12-10-2018 IPR017225 Cell shape-determining protein MreD, predicted NPD12_1245 955d7207748fa77a98b76a9f1cf66ba4 235 SMART SM00448 2 115 1.6E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1245 955d7207748fa77a98b76a9f1cf66ba4 235 Gene3D G3DSA:2.40.50.1020 126 221 5.6E-21 T 12-10-2018 NPD12_1245 955d7207748fa77a98b76a9f1cf66ba4 235 Pfam PF04397 LytTr DNA-binding domain 138 226 4.7E-22 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_1245 955d7207748fa77a98b76a9f1cf66ba4 235 SMART SM00850 135 227 6.8E-25 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_1245 955d7207748fa77a98b76a9f1cf66ba4 235 Gene3D G3DSA:3.40.50.2300 1 125 9.8E-23 T 12-10-2018 NPD12_1245 955d7207748fa77a98b76a9f1cf66ba4 235 SUPERFAMILY SSF52172 1 126 2.7E-18 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1245 955d7207748fa77a98b76a9f1cf66ba4 235 Pfam PF00072 Response regulator receiver domain 5 114 2.6E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_767 8a7f5f80e02876ee55539711961475cc 154 Pfam PF00583 Acetyltransferase (GNAT) family 32 143 2.1E-16 T 12-10-2018 IPR000182 GNAT domain NPD12_767 8a7f5f80e02876ee55539711961475cc 154 SUPERFAMILY SSF55729 1 147 1.42E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_767 8a7f5f80e02876ee55539711961475cc 154 Gene3D G3DSA:3.40.630.30 3 153 7.5E-36 T 12-10-2018 NPD12_3662 8235bf6d8088739559348f42604a29f6 146 PIRSF PIRSF005520 6 141 2.9E-51 T 12-10-2018 IPR008226 Mini-ribonuclease 3 family NPD12_3662 8235bf6d8088739559348f42604a29f6 146 Pfam PF00636 Ribonuclease III domain 22 120 2.6E-14 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 NPD12_3662 8235bf6d8088739559348f42604a29f6 146 Gene3D G3DSA:1.10.1520.10 7 140 2.4E-44 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 NPD12_3662 8235bf6d8088739559348f42604a29f6 146 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 12 137 28.462 T 12-10-2018 IPR008226 Mini-ribonuclease 3 family NPD12_3662 8235bf6d8088739559348f42604a29f6 146 SUPERFAMILY SSF69065 14 133 1.24E-34 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 SUPERFAMILY SSF52058 82 325 6.8E-42 T 12-10-2018 NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 SMART SM00365 298 319 600.0 T 12-10-2018 NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 SMART SM00365 210 231 15.0 T 12-10-2018 NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 SMART SM00365 254 278 93.0 T 12-10-2018 NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 SMART SM00365 188 209 9.3 T 12-10-2018 NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 SMART SM00365 166 187 0.064 T 12-10-2018 NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 Gene3D G3DSA:3.80.10.10 22 330 1.7E-49 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_2126 de2087504eb98f7652e5d762aa6c5895 331 Pfam PF12799 Leucine Rich repeats (2 copies) 167 205 1.9E-9 T 12-10-2018 IPR025875 Leucine rich repeat 4 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 18 428 38.448 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 294 3.0E-63 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 Gene3D G3DSA:3.20.20.10 37 294 7.6E-151 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 Gene3D G3DSA:2.40.37.10 16 424 7.6E-151 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 428 9.0E-143 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 SUPERFAMILY SSF51419 30 296 1.31E-79 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 SUPERFAMILY SSF50621 276 428 2.51E-47 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 167 176 4.2E-22 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 78 95 4.2E-22 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 395 417 4.2E-22 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 313 331 4.2E-22 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 295 385 2.3E-16 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 195 208 2.0E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 80 92 2.0E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 284 303 2.0E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 385 398 2.0E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 NPD12_3477 9750c021da4b719d9c5824d1aa901e48 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 60 78 2.0E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 NPD12_1242 102baf36c7b05ad52561e325fbdd9938 600 SUPERFAMILY SSF90123 3 335 7.72E-48 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1242 102baf36c7b05ad52561e325fbdd9938 600 SUPERFAMILY SSF52540 340 587 2.72E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1242 102baf36c7b05ad52561e325fbdd9938 600 Gene3D G3DSA:3.40.50.300 341 593 1.8E-84 T 12-10-2018 NPD12_1242 102baf36c7b05ad52561e325fbdd9938 600 Gene3D G3DSA:1.20.1560.10 8 331 6.3E-42 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1242 102baf36c7b05ad52561e325fbdd9938 600 SMART SM00382 377 563 8.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1242 102baf36c7b05ad52561e325fbdd9938 600 Pfam PF00005 ABC transporter 368 517 4.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1242 102baf36c7b05ad52561e325fbdd9938 600 Pfam PF00664 ABC transporter transmembrane region 29 292 7.0E-18 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 SUPERFAMILY SSF53218 182 329 9.95E-38 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 Gene3D G3DSA:3.40.980.10 182 324 6.3E-95 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 Pfam PF03454 MoeA C-terminal region (domain IV) 344 406 4.3E-10 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 174 2.6E-38 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 Gene3D G3DSA:2.170.190.11 50 148 6.3E-95 T 12-10-2018 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 260 295 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 SUPERFAMILY SSF63882 6 182 9.94E-47 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 183 320 1.1E-31 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 Pfam PF00994 Probable molybdopterin binding domain 187 323 6.4E-24 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 SMART SM00852 187 326 2.4E-39 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 Gene3D G3DSA:3.90.105.10 27 181 6.3E-95 T 12-10-2018 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 Gene3D G3DSA:2.40.340.10 337 408 2.4E-16 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2108 3715b35b57e1696b614c647e5eec51d6 408 SUPERFAMILY SSF63867 337 408 8.63E-13 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2051 53caa118c79be644dca08a501029b942 401 Pfam PF13742 OB-fold nucleic acid binding domain 6 100 3.1E-31 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 NPD12_2051 53caa118c79be644dca08a501029b942 401 Pfam PF02601 Exonuclease VII, large subunit 326 392 4.4E-10 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 NPD12_2051 53caa118c79be644dca08a501029b942 401 Pfam PF02601 Exonuclease VII, large subunit 124 343 7.4E-74 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 NPD12_2051 53caa118c79be644dca08a501029b942 401 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 395 2.6E-147 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 NPD12_2051 53caa118c79be644dca08a501029b942 401 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 396 26.352 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 SUPERFAMILY SSF52418 69 329 4.84E-90 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 Gene3D G3DSA:1.20.970.10 1 67 1.4E-28 T 12-10-2018 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 PIRSF PIRSF000478 1 434 1.5E-161 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 Gene3D G3DSA:3.90.1170.30 331 419 1.8E-145 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 1.1E-20 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 Pfam PF00591 Glycosyl transferase family, a/b domain 78 305 4.1E-41 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 418 1.2E-178 T 12-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 SUPERFAMILY SSF54680 332 433 2.75E-27 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 SUPERFAMILY SSF47648 1 69 2.09E-21 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 SMART SM00941 345 419 8.9E-27 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 Gene3D G3DSA:3.40.1030.10 77 330 1.8E-145 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2016 24010ac9a92795f15b98e7c239dbb6d4 434 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 4.2E-23 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 PIRSF PIRSF006004 1 342 5.6E-133 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 Gene3D G3DSA:1.10.150.530 2 61 1.5E-16 T 12-10-2018 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 Pfam PF04055 Radical SAM superfamily 105 265 3.2E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 Gene3D G3DSA:3.20.20.70 63 326 2.9E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 Pfam PF13394 4Fe-4S single cluster domain 110 199 7.5E-8 T 12-10-2018 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 339 1.2E-126 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 1 341 69.762 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 NPD12_2553 a07da573a3eb7bbd9683fc7c05b53914 342 SUPERFAMILY SSF102114 99 279 7.98E-11 T 12-10-2018 NPD12_3016 b3375e1f7e466eb25b3a6313f46a4358 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 5.3E-25 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3016 b3375e1f7e466eb25b3a6313f46a4358 88 Gene3D G3DSA:1.20.58.110 1 87 2.2E-27 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3016 b3375e1f7e466eb25b3a6313f46a4358 88 SUPERFAMILY SSF46992 3 86 8.76E-28 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3016 b3375e1f7e466eb25b3a6313f46a4358 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.305 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3016 b3375e1f7e466eb25b3a6313f46a4358 88 Pfam PF01649 Ribosomal protein S20 2 84 1.2E-26 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3016 b3375e1f7e466eb25b3a6313f46a4358 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 19 88 8.0E-17 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 1.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 1.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 1.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 1.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 SMART SM00387 307 426 2.2E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 Gene3D G3DSA:3.30.565.10 269 428 1.5E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 424 2.7E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_791 0cd14a097f72f6ee23b8dfad517f3a16 432 SUPERFAMILY SSF55874 287 423 6.94E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2682 f99a957382b876d603918dc386c362b7 239 Gene3D G3DSA:1.10.575.10 24 234 2.5E-34 T 12-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 NPD12_2682 f99a957382b876d603918dc386c362b7 239 SUPERFAMILY SSF48537 26 232 1.05E-43 T 12-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 NPD12_2682 f99a957382b876d603918dc386c362b7 239 ProDom PD003946 PHOSPHOLIPASE C PLCB HYDROLASE PRECURSOR PHOSPHATIDYLCHOLINE SIGNAL CHOLINEPHOSPHOHYDROLASE TOXIN PLC 79 226 1.0E-4 T 12-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 NPD12_2682 f99a957382b876d603918dc386c362b7 239 Pfam PF00882 Zinc dependent phospholipase C 40 184 1.7E-15 T 12-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 NPD12_2682 f99a957382b876d603918dc386c362b7 239 SMART SM00770 1 238 1.7E-61 T 12-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 NPD12_165 9a5f5339773a97cb053b87f93733faac 145 Pfam PF14437 MafB19-like deaminase 4 145 1.3E-34 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 NPD12_165 9a5f5339773a97cb053b87f93733faac 145 SUPERFAMILY SSF53927 3 143 2.84E-44 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_165 9a5f5339773a97cb053b87f93733faac 145 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 87 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 NPD12_165 9a5f5339773a97cb053b87f93733faac 145 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 5 145 45.367 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 NPD12_165 9a5f5339773a97cb053b87f93733faac 145 Gene3D G3DSA:3.40.140.10 1 145 7.0E-52 T 12-10-2018 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 Gene3D G3DSA:3.30.450.20 219 324 2.2E-14 T 12-10-2018 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 SUPERFAMILY SSF46689 549 642 2.83E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 SUPERFAMILY SSF52540 335 577 2.07E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 359 372 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 Gene3D G3DSA:3.30.450.40 17 203 7.1E-61 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 Gene3D G3DSA:1.10.8.60 507 574 6.6E-20 T 12-10-2018 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 SUPERFAMILY SSF55781 62 202 1.24E-5 T 12-10-2018 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 549 558 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 Pfam PF02954 Bacterial regulatory protein, Fis family 600 640 1.0E-15 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 SMART SM00382 355 499 1.8E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 422 437 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 Gene3D G3DSA:3.40.50.300 325 506 3.3E-63 T 12-10-2018 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 Pfam PF00158 Sigma-54 interaction domain 335 503 2.5E-67 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 623 643 1.0E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 606 623 1.0E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 SUPERFAMILY SSF55785 201 311 4.4E-8 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_1885 6a7ba0484ff18afa06184c0c524b1a37 654 Gene3D G3DSA:1.10.10.60 599 642 2.8E-16 T 12-10-2018 NPD12_392 2307f0299100e605df2f579dddbd2a53 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 76.684 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 NPD12_392 2307f0299100e605df2f579dddbd2a53 156 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site NPD12_392 2307f0299100e605df2f579dddbd2a53 156 SUPERFAMILY SSF74982 3 133 1.19E-54 T 12-10-2018 IPR023620 Small protein B NPD12_392 2307f0299100e605df2f579dddbd2a53 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 11 133 1.0E-60 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 NPD12_392 2307f0299100e605df2f579dddbd2a53 156 Pfam PF01668 SmpB protein 11 152 2.4E-63 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 NPD12_392 2307f0299100e605df2f579dddbd2a53 156 Gene3D G3DSA:2.40.280.10 2 129 4.4E-53 T 12-10-2018 IPR023620 Small protein B NPD12_392 2307f0299100e605df2f579dddbd2a53 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 151 1.9E-58 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 NPD12_3104 30ca8830c80002cf6f5b262e9e923885 209 Gene3D G3DSA:2.160.20.70 82 205 1.3E-37 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 NPD12_3104 30ca8830c80002cf6f5b262e9e923885 209 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 5 202 1.7E-30 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 NPD12_3104 30ca8830c80002cf6f5b262e9e923885 209 SUPERFAMILY SSF63848 100 203 6.93E-32 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 NPD12_3104 30ca8830c80002cf6f5b262e9e923885 209 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 102 199 4.9E-31 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 NPD12_3104 30ca8830c80002cf6f5b262e9e923885 209 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 4 204 22.945 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 NPD12_358 900cb0ef3db47638604e42b67949ae21 294 Gene3D G3DSA:3.40.50.10330 1 127 6.9E-31 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 NPD12_358 900cb0ef3db47638604e42b67949ae21 294 SMART SM00046 3 130 6.8E-4 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 NPD12_358 900cb0ef3db47638604e42b67949ae21 294 SUPERFAMILY SSF111331 1 290 9.65E-73 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily NPD12_358 900cb0ef3db47638604e42b67949ae21 294 Gene3D G3DSA:2.60.200.40 128 285 3.4E-39 T 12-10-2018 NPD12_358 900cb0ef3db47638604e42b67949ae21 294 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 289 2.2E-57 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase NPD12_358 900cb0ef3db47638604e42b67949ae21 294 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 126 2.0E-29 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 NPD12_1301 8361da928573668c029d9417751bf697 290 Gene3D G3DSA:1.10.3720.10 8 281 3.3E-46 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1301 8361da928573668c029d9417751bf697 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 275 5.4E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1301 8361da928573668c029d9417751bf697 290 SUPERFAMILY SSF161098 6 277 2.71E-42 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_292 2c74158fe8559d92d8a198055e073853 283 Gene3D G3DSA:1.10.8.10 3 81 2.1E-17 T 12-10-2018 NPD12_292 2c74158fe8559d92d8a198055e073853 283 SUPERFAMILY SSF53335 13 280 1.3E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_292 2c74158fe8559d92d8a198055e073853 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 186 192 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_292 2c74158fe8559d92d8a198055e073853 283 Gene3D G3DSA:3.40.50.150 82 283 5.4E-58 T 12-10-2018 NPD12_292 2c74158fe8559d92d8a198055e073853 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 278 9.2E-86 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 NPD12_292 2c74158fe8559d92d8a198055e073853 283 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 116 130 5.9E-6 T 12-10-2018 NPD12_292 2c74158fe8559d92d8a198055e073853 283 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 195 5.9E-6 T 12-10-2018 NPD12_292 2c74158fe8559d92d8a198055e073853 283 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 222 246 5.9E-6 T 12-10-2018 NPD12_292 2c74158fe8559d92d8a198055e073853 283 Pfam PF05175 Methyltransferase small domain 104 196 4.4E-14 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 NPD12_292 2c74158fe8559d92d8a198055e073853 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 282 42.338 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 NPD12_292 2c74158fe8559d92d8a198055e073853 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 16 281 1.2E-68 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 PIRSF PIRSF004803 1 554 5.2E-237 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 SMART SM00849 19 214 2.9E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 353 406 6.3E-9 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 SUPERFAMILY SSF56281 8 423 5.2E-96 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 Gene3D G3DSA:3.40.50.10710 206 356 8.3E-186 T 12-10-2018 NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 Gene3D G3DSA:3.60.15.10 10 441 8.3E-186 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 Pfam PF00753 Metallo-beta-lactamase superfamily 17 163 2.2E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 Gene3D G3DSA:3.10.20.580 448 554 2.9E-37 T 12-10-2018 NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 Hamap MF_01491 Ribonuclease J [rnj]. 2 554 47.635 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 NPD12_1542 8b43ecc3c81012876c188c786f0894f1 554 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 7 552 1.2E-198 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 NPD12_1319 cbe3d7c980d039bc7a4fc7c3d2f16cd6 314 Gene3D G3DSA:3.40.50.720 99 282 1.2E-114 T 12-10-2018 NPD12_1319 cbe3d7c980d039bc7a4fc7c3d2f16cd6 314 SUPERFAMILY SSF52283 15 129 2.46E-33 T 12-10-2018 NPD12_1319 cbe3d7c980d039bc7a4fc7c3d2f16cd6 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 302 2.8E-34 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 NPD12_1319 cbe3d7c980d039bc7a4fc7c3d2f16cd6 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 279 9.7E-60 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 NPD12_1319 cbe3d7c980d039bc7a4fc7c3d2f16cd6 314 SUPERFAMILY SSF51735 101 280 3.12E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1319 cbe3d7c980d039bc7a4fc7c3d2f16cd6 314 Gene3D G3DSA:3.40.50.720 5 295 1.2E-114 T 12-10-2018 NPD12_1319 cbe3d7c980d039bc7a4fc7c3d2f16cd6 314 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 342 164.54 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 326 1.6E-143 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 SMART SM00382 51 182 8.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 Gene3D G3DSA:1.10.8.60 182 255 1.5E-29 T 12-10-2018 NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 Gene3D G3DSA:1.10.10.10 257 335 4.0E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 SUPERFAMILY SSF52540 20 251 5.29E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 SUPERFAMILY SSF46785 257 328 8.43E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 253 326 6.2E-34 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 Gene3D G3DSA:3.40.50.300 20 181 1.4E-41 T 12-10-2018 NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 11 235 3.7E-115 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 NPD12_3179 f8f0367c87ea33bcfbf08ea63d081559 342 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 250 332 1.0E-31 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 SUPERFAMILY SSF116734 539 723 3.43E-5 T 12-10-2018 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 Pfam PF07669 Eco57I restriction-modification methylase 371 483 4.9E-9 T 12-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 372 384 1.5E-16 T 12-10-2018 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 178 194 1.5E-16 T 12-10-2018 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 412 436 1.5E-16 T 12-10-2018 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 208 222 1.5E-16 T 12-10-2018 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 375 381 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 SUPERFAMILY SSF53335 91 512 1.18E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_1455 01390fc1c7df78e202da4be2f7dbddc5 741 Pfam PF12950 TaqI-like C-terminal specificity domain 564 681 1.3E-26 T 12-10-2018 IPR025931 TaqI-like C-terminal specificity domain NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 Gene3D G3DSA:3.40.50.1220 206 334 1.4E-54 T 12-10-2018 NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 Pfam PF01012 Electron transfer flavoprotein domain 9 187 1.3E-47 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 273 299 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 SMART SM00893 9 198 1.8E-56 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 SUPERFAMILY SSF52467 210 328 2.89E-46 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 SUPERFAMILY SSF52402 7 201 5.86E-58 T 12-10-2018 NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 PIRSF PIRSF000089 5 334 2.5E-118 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 Gene3D G3DSA:3.40.50.620 5 205 3.6E-80 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3308 30b748f99bd98725cfb8070aae64efc9 334 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 210 292 1.1E-35 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Gene3D G3DSA:2.120.10.90 744 947 2.6E-24 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Gene3D G3DSA:3.90.199.10 37 496 3.9E-192 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Gene3D G3DSA:2.120.10.90 512 743 7.3E-45 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 37 483 2.9E-143 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 SMART SM00434 16 476 7.5E-218 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 SUPERFAMILY SSF101904 724 945 4.97E-28 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 517 558 1.0 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 564 595 1.2 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 858 903 1.1E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 622 660 0.0038 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Gene3D G3DSA:1.10.268.10 381 470 3.9E-192 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 SUPERFAMILY SSF101904 512 737 2.09E-46 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 SUPERFAMILY SSF56719 36 499 2.75E-164 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 NPD12_2804 cb2740e7b0c5e06bf9230a96e748e11e 956 Gene3D G3DSA:3.30.1360.40 241 344 3.9E-192 T 12-10-2018 NPD12_1640 fc0b55e96e38c595615026e7415e0196 439 Gene3D G3DSA:1.20.1740.10 7 439 8.6E-98 T 12-10-2018 NPD12_1640 fc0b55e96e38c595615026e7415e0196 439 Pfam PF13520 Amino acid permease 13 408 1.1E-65 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_1640 fc0b55e96e38c595615026e7415e0196 439 PIRSF PIRSF006060 1 439 2.0E-89 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_3194 8d0c54ed85c90cc3a390af7c7093daa2 335 Gene3D G3DSA:3.40.47.40 2 335 5.6E-150 T 12-10-2018 IPR038369 Stage V sporulation AD superfamily NPD12_3194 8d0c54ed85c90cc3a390af7c7093daa2 335 PIRSF PIRSF011570 2 335 1.5E-150 T 12-10-2018 IPR010894 Stage V sporulation AD NPD12_3194 8d0c54ed85c90cc3a390af7c7093daa2 335 SUPERFAMILY SSF53901 57 311 3.29E-15 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_3194 8d0c54ed85c90cc3a390af7c7093daa2 335 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 6 334 1.6E-163 T 12-10-2018 IPR010894 Stage V sporulation AD NPD12_3194 8d0c54ed85c90cc3a390af7c7093daa2 335 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 8 334 1.4E-151 T 12-10-2018 IPR010894 Stage V sporulation AD NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 112 129 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 102 116 3.5E-16 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 85 98 3.5E-16 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 117 130 3.5E-16 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 156 2.5E-39 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 Pfam PF00364 Biotin-requiring enzyme 82 155 1.3E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 Gene3D G3DSA:2.40.50.100 79 155 1.4E-27 T 12-10-2018 NPD12_67 a7d158ac620be0de113b6fe95fa47556 158 SUPERFAMILY SSF51230 79 155 3.66E-23 T 12-10-2018 IPR011053 Single hybrid motif NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 248 9.3E-18 T 12-10-2018 IPR000014 PAS domain NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 SUPERFAMILY SSF55073 261 418 6.36E-47 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 SUPERFAMILY SSF55785 123 243 1.92E-17 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 SMART SM00091 138 204 2.3E-6 T 12-10-2018 IPR000014 PAS domain NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 SMART SM00267 245 417 3.7E-55 T 12-10-2018 IPR000160 GGDEF domain NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 Pfam PF13426 PAS domain 38 124 0.085 T 12-10-2018 IPR000014 PAS domain NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 Pfam PF13426 PAS domain 149 244 2.4E-9 T 12-10-2018 IPR000014 PAS domain NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 Gene3D G3DSA:3.30.450.20 133 247 3.4E-17 T 12-10-2018 NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 416 2.2E-45 T 12-10-2018 IPR000160 GGDEF domain NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 Gene3D G3DSA:3.30.70.270 250 419 1.6E-57 T 12-10-2018 NPD12_1398 4b9c00a5a9ade29f01e4099cb744cffe 419 Pfam PF00990 Diguanylate cyclase, GGDEF domain 256 413 3.3E-50 T 12-10-2018 IPR000160 GGDEF domain NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 SUPERFAMILY SSF47323 314 463 1.05E-35 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 Pfam PF09190 DALR domain 353 415 2.5E-18 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 464 4.0E-182 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 311 2.6E-135 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 Gene3D G3DSA:1.20.120.1910 304 464 4.4E-41 T 12-10-2018 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 Gene3D G3DSA:3.40.50.620 1 303 1.3E-136 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 SMART SM00840 353 416 3.9E-19 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 SUPERFAMILY SSF52374 2 309 2.63E-102 T 12-10-2018 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 8.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 8.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 8.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 8.9E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 NPD12_3663 24ab3ec0d26435fd9bcf223d4f4e1c02 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 465 38.832 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 NPD12_3100 46060a59697ac617b673e42bcc784add 261 SUPERFAMILY SSF51261 76 255 9.42E-48 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_3100 46060a59697ac617b673e42bcc784add 261 Pfam PF01551 Peptidase family M23 158 252 6.0E-30 T 12-10-2018 IPR016047 Peptidase M23 NPD12_3100 46060a59697ac617b673e42bcc784add 261 Gene3D G3DSA:2.70.70.10 108 260 8.1E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_3623 d49d5ddbc844314380738e853a7c803a 119 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 8 119 2.7E-42 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3623 d49d5ddbc844314380738e853a7c803a 119 SUPERFAMILY SSF53137 7 117 1.0E-51 T 12-10-2018 NPD12_3623 d49d5ddbc844314380738e853a7c803a 119 Gene3D G3DSA:3.30.420.100 5 119 1.3E-43 T 12-10-2018 NPD12_3623 d49d5ddbc844314380738e853a7c803a 119 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 119 29.503 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3623 d49d5ddbc844314380738e853a7c803a 119 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 119 1.2E-47 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 SUPERFAMILY SSF55021 3 67 4.23E-5 T 12-10-2018 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 Gene3D G3DSA:3.30.450.20 89 193 3.2E-14 T 12-10-2018 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 SMART SM00382 225 369 4.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 472 517 1.0E-10 T 12-10-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 Gene3D G3DSA:3.30.70.260 1 79 1.8E-19 T 12-10-2018 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 423 432 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 292 307 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 SUPERFAMILY SSF55785 77 180 4.4E-8 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 229 242 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 Gene3D G3DSA:3.40.50.300 194 376 2.4E-64 T 12-10-2018 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 Gene3D G3DSA:1.10.8.60 377 447 3.5E-21 T 12-10-2018 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 SUPERFAMILY SSF52540 204 450 4.48E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 Pfam PF00158 Sigma-54 interaction domain 205 373 1.2E-67 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 SUPERFAMILY SSF46689 470 517 1.15E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 Pfam PF13426 PAS domain 90 185 2.7E-6 T 12-10-2018 IPR000014 PAS domain NPD12_163 0b2ef9aaa04a27f2cdeb1e949be65959 520 Gene3D G3DSA:1.10.10.60 463 518 4.5E-11 T 12-10-2018 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 SUPERFAMILY SSF52833 2 105 4.23E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 Gene3D G3DSA:3.40.30.10 1 105 2.1E-36 T 12-10-2018 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 Pfam PF00085 Thioredoxin 2 104 1.4E-33 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 104 1.7E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 PIRSF PIRSF000077 1 105 8.7E-42 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 PRINTS PR00421 Thioredoxin family signature 21 29 1.7E-8 T 12-10-2018 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 PRINTS PR00421 Thioredoxin family signature 29 38 1.7E-8 T 12-10-2018 NPD12_3592 9f9192e126ecabf8d23be9605a808535 105 PRINTS PR00421 Thioredoxin family signature 69 80 1.7E-8 T 12-10-2018 NPD12_3556 c14c797db786a27502ca1b7652d73666 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 124 26.476 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 NPD12_3556 c14c797db786a27502ca1b7652d73666 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 87 6.0E-22 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 NPD12_3556 c14c797db786a27502ca1b7652d73666 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 120 5.1E-21 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_3556 c14c797db786a27502ca1b7652d73666 126 Gene3D G3DSA:3.90.470.20 1 123 2.8E-38 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_3556 c14c797db786a27502ca1b7652d73666 126 SUPERFAMILY SSF56214 2 123 1.31E-31 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_3556 c14c797db786a27502ca1b7652d73666 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 123 1.3E-35 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 NPD12_3556 c14c797db786a27502ca1b7652d73666 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 123 3.7E-31 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 NPD12_3183 4764c3a040dafb5aba70370afa4c189d 216 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 198 3.7E-57 T 12-10-2018 IPR015796 Impact family, bacterial/archaeal NPD12_3183 4764c3a040dafb5aba70370afa4c189d 216 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 77 106 - T 12-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site NPD12_3183 4764c3a040dafb5aba70370afa4c189d 216 SUPERFAMILY SSF54980 136 201 1.87E-8 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3183 4764c3a040dafb5aba70370afa4c189d 216 SUPERFAMILY SSF54211 2 130 4.55E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3183 4764c3a040dafb5aba70370afa4c189d 216 Gene3D G3DSA:3.30.230.30 1 131 5.8E-45 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily NPD12_3183 4764c3a040dafb5aba70370afa4c189d 216 Pfam PF01205 Uncharacterized protein family UPF0029 17 120 2.2E-29 T 12-10-2018 IPR001498 Impact, N-terminal NPD12_3183 4764c3a040dafb5aba70370afa4c189d 216 Pfam PF09186 Domain of unknown function (DUF1949) 139 193 4.1E-13 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal NPD12_1487 2ab31a9cdcdf7c34486dc8363d1d1b6e 340 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 197 304 3.7E-27 T 12-10-2018 IPR006528 Phage head morphogenesis domain NPD12_1487 2ab31a9cdcdf7c34486dc8363d1d1b6e 340 Pfam PF04233 Phage Mu protein F like protein 196 301 2.2E-18 T 12-10-2018 IPR006528 Phage head morphogenesis domain NPD12_2479 5965038c095539d8fb6ad3f6dbf486f5 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 29 249 7.8E-85 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 NPD12_2479 5965038c095539d8fb6ad3f6dbf486f5 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 195 212 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 NPD12_2479 5965038c095539d8fb6ad3f6dbf486f5 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 22 250 41.771 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 NPD12_2479 5965038c095539d8fb6ad3f6dbf486f5 252 Gene3D G3DSA:3.40.1180.10 4 251 6.4E-100 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 NPD12_2479 5965038c095539d8fb6ad3f6dbf486f5 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 22 249 4.4E-90 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 NPD12_2479 5965038c095539d8fb6ad3f6dbf486f5 252 SUPERFAMILY SSF64005 17 244 3.01E-93 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 NPD12_3670 cdd27e44bea245b176d54775e660d993 353 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 24 136 7.1E-26 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal NPD12_3670 cdd27e44bea245b176d54775e660d993 353 Gene3D G3DSA:1.20.1260.110 142 286 1.7E-44 T 12-10-2018 IPR038331 DisA, linker domain superfamily NPD12_3670 cdd27e44bea245b176d54775e660d993 353 SUPERFAMILY SSF47781 257 343 4.13E-13 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_3670 cdd27e44bea245b176d54775e660d993 353 Gene3D G3DSA:1.10.150.20 287 349 2.3E-24 T 12-10-2018 NPD12_3670 cdd27e44bea245b176d54775e660d993 353 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 3 351 44.843 T 12-10-2018 IPR023763 DNA integrity scanning protein, DisA NPD12_3670 cdd27e44bea245b176d54775e660d993 353 Gene3D G3DSA:3.40.1700.10 5 141 9.3E-56 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily NPD12_3670 cdd27e44bea245b176d54775e660d993 353 SUPERFAMILY SSF143597 15 141 1.44E-30 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily NPD12_3670 cdd27e44bea245b176d54775e660d993 353 Pfam PF10635 DisA bacterial checkpoint controller linker region 141 275 4.8E-53 T 12-10-2018 IPR018906 DNA integrity scanning, DisA, linker region NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 Pfam PF01580 FtsK/SpoIIIE family 529 583 2.2E-15 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 Pfam PF01580 FtsK/SpoIIIE family 392 525 3.1E-45 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 Gene3D G3DSA:1.10.10.10 675 742 2.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 Gene3D G3DSA:3.30.980.40 283 387 3.5E-38 T 12-10-2018 NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 SMART SM00843 681 746 2.3E-34 T 12-10-2018 IPR018541 FtsK gamma domain NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 Pfam PF09397 Ftsk gamma domain 683 743 1.4E-27 T 12-10-2018 IPR018541 FtsK gamma domain NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 SUPERFAMILY SSF46785 682 747 1.29E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 40 176 2.2E-8 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 Gene3D G3DSA:3.40.50.300 389 670 2.2E-108 T 12-10-2018 NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 SMART SM00382 427 605 0.0041 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2455 a828e0add6466aa9dec7d9eee152e7bd 758 SUPERFAMILY SSF52540 365 653 9.74E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1770 7c16d081d870eeda99143089cd83ca30 180 Gene3D G3DSA:3.40.50.360 5 156 2.9E-10 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1770 7c16d081d870eeda99143089cd83ca30 180 Pfam PF12724 Flavodoxin domain 7 142 8.6E-30 T 12-10-2018 IPR026816 Flavodoxin domain NPD12_1770 7c16d081d870eeda99143089cd83ca30 180 SUPERFAMILY SSF52218 3 143 2.95E-18 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 196 42.268 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 Gene3D G3DSA:3.30.230.40 1 91 1.3E-34 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 SUPERFAMILY SSF54211 89 181 4.55E-37 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 SUPERFAMILY SSF54211 6 88 3.04E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 176 6.3E-66 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 NPD12_1808 33bdfcd1de565da1d495f0b84ac4149b 196 Gene3D G3DSA:3.30.230.40 92 196 4.2E-39 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Gene3D G3DSA:3.40.50.1000 529 665 2.7E-79 T 12-10-2018 IPR023214 HAD superfamily NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 355 361 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Pfam PF00122 E1-E2 ATPase 140 333 2.7E-46 T 12-10-2018 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Gene3D G3DSA:2.70.150.10 40 256 2.1E-86 T 12-10-2018 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 SUPERFAMILY SSF81660 320 525 9.81E-41 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Pfam PF00702 haloacid dehalogenase-like hydrolase 349 635 2.9E-20 T 12-10-2018 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Gene3D G3DSA:3.40.1110.10 412 528 2.7E-79 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 246 388 3.1E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 113 206 5.1E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 588 710 4.7E-32 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 SUPERFAMILY SSF56784 341 661 3.04E-39 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 SMART SM00831 22 95 2.1E-15 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Gene3D G3DSA:1.20.1110.10 73 349 2.1E-86 T 12-10-2018 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 SUPERFAMILY SSF81653 144 252 1.44E-27 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 SUPERFAMILY SSF81665 23 878 3.4E-104 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Pfam PF00690 Cation transporter/ATPase, N-terminus 25 90 1.7E-19 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Gene3D G3DSA:3.40.50.1000 350 362 2.1E-86 T 12-10-2018 IPR023214 HAD superfamily NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Gene3D G3DSA:1.20.1110.10 666 781 2.7E-79 T 12-10-2018 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 14 880 0.0 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 834 855 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 266 282 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 283 302 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 784 805 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 729 742 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 749 765 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 387 400 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 679 694 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 PRINTS PR01836 Magnesium-transporting ATPase signature 697 708 4.5E-80 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Pfam PF00689 Cation transporting ATPase, C-terminus 704 872 2.0E-12 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 NPD12_2924 f18bf84c8ea02c4df329170c29db1b36 881 Gene3D G3DSA:3.40.1110.10 363 374 2.1E-86 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_2082 4d8347caf9b9107771887f22109abc41 467 Gene3D G3DSA:3.90.1150.160 362 463 3.6E-29 T 12-10-2018 NPD12_2082 4d8347caf9b9107771887f22109abc41 467 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 22 447 2.9E-200 T 12-10-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 NPD12_2082 4d8347caf9b9107771887f22109abc41 467 SUPERFAMILY SSF53383 12 447 2.2E-127 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2082 4d8347caf9b9107771887f22109abc41 467 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 51 382 2.4E-71 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 NPD12_2082 4d8347caf9b9107771887f22109abc41 467 Gene3D G3DSA:3.40.640.10 67 361 9.3E-80 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 10 109 2.2E-47 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 9 278 6.2E-125 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 SUPERFAMILY SSF52096 13 277 2.49E-92 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 Gene3D G3DSA:3.90.226.10 1 279 1.5E-104 T 12-10-2018 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 74 92 3.6E-44 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 130 143 3.6E-44 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 158 167 3.6E-44 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 49 60 3.6E-44 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 95 111 3.6E-44 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 114 127 3.6E-44 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_63 35bc38e01037754c24cfb44a01d7d98b 279 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 277 41.013 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_1442 85df02280caa48789ec2b4cad35c76f8 486 Gene3D G3DSA:3.40.309.10 263 449 4.5E-160 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 NPD12_1442 85df02280caa48789ec2b4cad35c76f8 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 NPD12_1442 85df02280caa48789ec2b4cad35c76f8 486 Pfam PF00171 Aldehyde dehydrogenase family 20 480 1.8E-163 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 NPD12_1442 85df02280caa48789ec2b4cad35c76f8 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 NPD12_1442 85df02280caa48789ec2b4cad35c76f8 486 Gene3D G3DSA:3.40.605.10 16 478 4.5E-160 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 NPD12_1442 85df02280caa48789ec2b4cad35c76f8 486 SUPERFAMILY SSF53720 8 483 2.49E-153 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 SUPERFAMILY SSF53163 1 324 1.73E-117 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 Gene3D G3DSA:3.40.50.1450 1 324 4.2E-122 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 Pfam PF03418 Germination protease 9 253 9.9E-88 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 Hamap MF_00626 Germination protease [gpr]. 1 324 158.984 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 3 302 8.0E-100 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 PIRSF PIRSF019549 1 256 1.6E-114 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 PIRSF PIRSF019549 248 324 9.6E-21 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 NPD12_3015 71d0c9f3f3be5c3f152e4848405a279c 324 TIGRFAM TIGR01441 GPR: GPR endopeptidase 3 249 3.2E-105 T 12-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 NPD12_2089 fa0f95a7122fd8d5c8214b7a4de41945 157 Gene3D G3DSA:3.30.1060.10 1 157 2.7E-71 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_2089 fa0f95a7122fd8d5c8214b7a4de41945 157 Pfam PF01625 Peptide methionine sulfoxide reductase 3 153 1.4E-65 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_2089 fa0f95a7122fd8d5c8214b7a4de41945 157 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 157 37.505 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_2089 fa0f95a7122fd8d5c8214b7a4de41945 157 SUPERFAMILY SSF55068 1 155 5.1E-70 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_2089 fa0f95a7122fd8d5c8214b7a4de41945 157 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 152 4.3E-65 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 SUPERFAMILY SSF64518 1 278 5.36E-66 T 12-10-2018 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 Pfam PF00700 Bacterial flagellin C-terminal helical region 193 278 3.6E-14 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 Gene3D G3DSA:1.10.8.410 232 279 1.7E-12 T 12-10-2018 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 Gene3D G3DSA:1.20.1330.10 48 231 2.0E-44 T 12-10-2018 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 140 4.4E-28 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 PRINTS PR00207 Flagellin signature 109 132 3.0E-11 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 PRINTS PR00207 Flagellin signature 74 93 3.0E-11 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2716 2387f22563622cf58f2ac8fb63965a84 284 PRINTS PR00207 Flagellin signature 35 52 3.0E-11 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_3723 2bc5a1c36a06f8059318ef11f06d5af5 69 Gene3D G3DSA:1.10.260.40 4 68 1.5E-6 T 12-10-2018 NPD12_3723 2bc5a1c36a06f8059318ef11f06d5af5 69 SUPERFAMILY SSF47413 16 67 8.0E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3723 2bc5a1c36a06f8059318ef11f06d5af5 69 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 68 1.9E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_516 6df147848ccccf344c7c8528203c984a 228 SMART SM00862 149 225 5.3E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_516 6df147848ccccf344c7c8528203c984a 228 Gene3D G3DSA:1.10.10.10 128 228 8.1E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_516 6df147848ccccf344c7c8528203c984a 228 SMART SM00448 2 113 1.5E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_516 6df147848ccccf344c7c8528203c984a 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 3.2E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_516 6df147848ccccf344c7c8528203c984a 228 Gene3D G3DSA:3.40.50.2300 2 127 2.9E-38 T 12-10-2018 NPD12_516 6df147848ccccf344c7c8528203c984a 228 Pfam PF00072 Response regulator receiver domain 4 113 2.1E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_516 6df147848ccccf344c7c8528203c984a 228 SUPERFAMILY SSF52172 3 176 7.62E-41 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 SMART SM00388 413 479 8.4E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 SMART SM00387 527 636 8.8E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 SUPERFAMILY SSF47384 402 480 4.9E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 Pfam PF00512 His Kinase A (phospho-acceptor) domain 414 479 3.4E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 528 621 2.2E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 SUPERFAMILY SSF55874 468 620 1.31E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 Gene3D G3DSA:3.30.565.10 479 636 2.7E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 592 6.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 567 6.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 617 6.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2088 1fc99b0c81b6e828740ccbffb7fe4c16 637 Gene3D G3DSA:1.10.287.130 406 478 4.5E-20 T 12-10-2018 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 313 7.7E-50 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 328 2.4E-137 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 SUPERFAMILY SSF55347 129 314 2.88E-73 T 12-10-2018 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 PIRSF PIRSF000148 2 330 7.5E-126 T 12-10-2018 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 119 2.3E-35 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 SUPERFAMILY SSF51735 3 156 7.76E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 Gene3D G3DSA:3.40.50.720 5 324 1.2E-133 T 12-10-2018 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 SMART SM00859 4 121 1.1E-44 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 Gene3D G3DSA:3.30.360.10 128 310 1.2E-133 T 12-10-2018 NPD12_3264 1b59d7c88eb940830673e4494bf7ab9d 330 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 327 36.977 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_672 d8768355d08b85327a73ee1a0b3ec2da 314 SUPERFAMILY SSF53474 10 305 3.62E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_672 d8768355d08b85327a73ee1a0b3ec2da 314 Pfam PF12146 Serine aminopeptidase, S33 28 292 3.4E-61 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 NPD12_672 d8768355d08b85327a73ee1a0b3ec2da 314 Gene3D G3DSA:3.40.50.1820 1 311 1.9E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 SUPERFAMILY SSF52540 62 286 5.73E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 SMART SM00382 85 239 6.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 Pfam PF13481 AAA domain 60 217 1.7E-14 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 Gene3D G3DSA:3.30.230.10 296 452 1.7E-15 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 445 6.4E-171 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 Pfam PF13541 Subunit ChlI of Mg-chelatase 341 426 1.1E-9 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 Gene3D G3DSA:3.40.50.300 57 281 2.1E-44 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 Hamap MF_01498 DNA repair protein RadA [radA]. 21 452 41.4 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 SUPERFAMILY SSF54211 250 452 2.5E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 PRINTS PR01874 DNA repair protein radA signature 169 193 1.3E-90 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 PRINTS PR01874 DNA repair protein radA signature 119 136 1.3E-90 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 PRINTS PR01874 DNA repair protein radA signature 10 34 1.3E-90 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 PRINTS PR01874 DNA repair protein radA signature 243 269 1.3E-90 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 PRINTS PR01874 DNA repair protein radA signature 317 340 1.3E-90 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 PRINTS PR01874 DNA repair protein radA signature 77 105 1.3E-90 T 12-10-2018 NPD12_3671 2641f65a8803e526aa3252e2be7dc9f4 452 PRINTS PR01874 DNA repair protein radA signature 208 236 1.3E-90 T 12-10-2018 NPD12_2345 3fb645ba35ab4939c47610422c39b57c 281 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 257 6.0E-18 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain NPD12_2345 3fb645ba35ab4939c47610422c39b57c 281 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 92 103 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2345 3fb645ba35ab4939c47610422c39b57c 281 Pfam PF00037 4Fe-4S binding domain 61 83 5.7E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2345 3fb645ba35ab4939c47610422c39b57c 281 Pfam PF00037 4Fe-4S binding domain 86 108 3.1E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2345 3fb645ba35ab4939c47610422c39b57c 281 SUPERFAMILY SSF52540 4 279 3.72E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2345 3fb645ba35ab4939c47610422c39b57c 281 Gene3D G3DSA:3.30.70.20 62 110 7.9E-9 T 12-10-2018 NPD12_2976 1f2644ddbbe0df02ed6cc77da927a0e9 719 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 496 700 9.2E-54 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal NPD12_2976 1f2644ddbbe0df02ed6cc77da927a0e9 719 Pfam PF12698 ABC-2 family transporter protein 378 696 1.6E-13 T 12-10-2018 NPD12_2976 1f2644ddbbe0df02ed6cc77da927a0e9 719 Pfam PF12698 ABC-2 family transporter protein 23 167 1.4E-10 T 12-10-2018 NPD12_2976 1f2644ddbbe0df02ed6cc77da927a0e9 719 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 12 169 2.2E-46 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal NPD12_2996 b8d8dac617b0e2a4ebe9b1e0be1a9e20 232 SUPERFAMILY SSF48317 42 231 1.31E-22 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily NPD12_2996 b8d8dac617b0e2a4ebe9b1e0be1a9e20 232 Gene3D G3DSA:1.10.3830.10 1 117 2.0E-36 T 12-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 NPD12_2996 b8d8dac617b0e2a4ebe9b1e0be1a9e20 232 SMART SM00014 133 228 1.5E-5 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase NPD12_2996 b8d8dac617b0e2a4ebe9b1e0be1a9e20 232 Pfam PF01569 PAP2 superfamily 158 230 4.2E-11 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase NPD12_2996 b8d8dac617b0e2a4ebe9b1e0be1a9e20 232 Pfam PF01219 Prokaryotic diacylglycerol kinase 11 112 1.0E-32 T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 NPD12_2996 b8d8dac617b0e2a4ebe9b1e0be1a9e20 232 Gene3D G3DSA:1.20.144.10 154 232 1.5E-12 T 12-10-2018 NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 PIRSF PIRSF026579 1 183 1.2E-89 T 12-10-2018 IPR014213 Sporulation stage V, protein T NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 182 1.0E-89 T 12-10-2018 IPR014213 Sporulation stage V, protein T NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 9.4E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 Gene3D G3DSA:2.10.260.10 1 51 2.9E-23 T 12-10-2018 NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 SUPERFAMILY SSF89447 1 51 3.66E-14 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 SUPERFAMILY SSF55781 96 178 2.35E-7 T 12-10-2018 NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 Gene3D G3DSA:3.30.450.40 56 183 2.2E-40 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.6E-14 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 SMART SM00966 8 52 1.6E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 NPD12_7 a139f907579d15a2f153aa1922a1b1e1 183 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 182 7.2E-47 T 12-10-2018 IPR039472 Sporulation stage V protein T, GAF domain NPD12_1824 526b2bffc14b018b37f3e26506e9a765 247 TIGRFAM TIGR03733 lanti_perm_MutG: lantibiotic protection ABC transporter permease subunit, MutG family 6 244 7.2E-96 T 12-10-2018 IPR022294 Lantibiotic protection ABC transporter permease subunit, MutG family NPD12_1824 526b2bffc14b018b37f3e26506e9a765 247 Pfam PF12730 ABC-2 family transporter protein 8 152 7.8E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 Gene3D G3DSA:3.50.50.60 278 460 5.8E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 Gene3D G3DSA:3.50.50.60 139 277 3.5E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 139 447 1.2E-36 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 14 458 4.9E-179 T 12-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 17 127 7.6E-45 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 SUPERFAMILY SSF51971 138 391 8.24E-69 T 12-10-2018 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 SUPERFAMILY SSF51971 367 459 3.18E-6 T 12-10-2018 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 Gene3D G3DSA:1.10.1060.10 2 138 6.4E-43 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 SUPERFAMILY SSF46548 9 149 1.15E-34 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 PRINTS PR00419 Adrenodoxin reductase family signature 140 162 6.4E-19 T 12-10-2018 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 PRINTS PR00419 Adrenodoxin reductase family signature 206 216 6.4E-19 T 12-10-2018 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 PRINTS PR00419 Adrenodoxin reductase family signature 282 296 6.4E-19 T 12-10-2018 NPD12_1884 7aaeff06b2ce4119e2c2004f1df98014 460 PRINTS PR00419 Adrenodoxin reductase family signature 163 176 6.4E-19 T 12-10-2018 NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 Gene3D G3DSA:1.10.8.420 6 53 2.0E-19 T 12-10-2018 NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 105.596 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 Pfam PF13662 Toprim domain 81 171 5.1E-24 T 12-10-2018 IPR006171 TOPRIM domain NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 SUPERFAMILY SSF111304 4 198 1.83E-76 T 12-10-2018 IPR023627 Recombination protein RecR NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 ProSitePatterns PS01300 RecR protein signature. 58 79 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 Pfam PF02132 RecR protein 40 79 1.2E-17 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 SMART SM00493 81 165 7.2E-15 T 12-10-2018 IPR006171 TOPRIM domain NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 Gene3D G3DSA:3.40.1360.10 78 198 6.8E-47 T 12-10-2018 NPD12_169 36ccde2f0b9630cacceed3fa9363f75a 198 TIGRFAM TIGR00615 recR: recombination protein RecR 4 195 1.4E-80 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 SUPERFAMILY SSF53774 1 328 1.24E-99 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 Gene3D G3DSA:3.40.50.1170 1 206 3.8E-65 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 Pfam PF00710 Asparaginase, N-terminal 3 193 2.0E-53 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 PRINTS PR00139 Asparaginase/glutaminase family signature 254 272 2.3E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 2.3E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 PRINTS PR00139 Asparaginase/glutaminase family signature 81 99 2.3E-14 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 PIRSF PIRSF001220 1 327 5.6E-93 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 Gene3D G3DSA:3.40.50.40 207 332 6.3E-35 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 SMART SM00870 3 320 2.0E-137 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 NPD12_2564 a09eb4e86b48c5bb8f2a3f05885706db 333 PIRSF PIRSF500176 1 328 8.2E-86 T 12-10-2018 NPD12_2529 90769eff75ce07d843983bc27d89613d 703 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 254 594 7.5E-26 T 12-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 NPD12_2529 90769eff75ce07d843983bc27d89613d 703 TIGRFAM TIGR04480 D_pro_red_PrdA: D-proline reductase (dithiol), PrdA proprotein 97 673 6.1E-265 T 12-10-2018 IPR031002 D-proline reductase, PrdA proprotein GO:0050002|GO:0055114 KEGG: 00330+1.21.4.1 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Gene3D G3DSA:2.60.120.380 558 672 7.2E-20 T 12-10-2018 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Gene3D G3DSA:2.60.120.380 340 432 2.2E-6 T 12-10-2018 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Gene3D G3DSA:3.40.50.12090 61 155 1.4E-10 T 12-10-2018 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Gene3D G3DSA:3.40.50.12090 176 249 2.1E-7 T 12-10-2018 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Gene3D G3DSA:2.60.120.380 439 556 4.5E-23 T 12-10-2018 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 SUPERFAMILY SSF89260 441 538 2.88E-11 T 12-10-2018 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Pfam PF04122 Putative cell wall binding repeat 2 231 318 4.3E-18 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Pfam PF04122 Putative cell wall binding repeat 2 137 222 8.7E-19 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 Pfam PF04122 Putative cell wall binding repeat 2 38 124 1.8E-19 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_543 7aeaecf3ba626887dee3cb37ef73a8a0 689 SUPERFAMILY SSF89260 562 670 3.92E-12 T 12-10-2018 NPD12_2961 9374e5d995d45143a861496f98d7fada 441 Pfam PF01595 Domain of unknown function DUF21 10 209 7.1E-46 T 12-10-2018 IPR002550 CNNM, transmembrane domain NPD12_2961 9374e5d995d45143a861496f98d7fada 441 SUPERFAMILY SSF54631 219 356 8.42E-29 T 12-10-2018 NPD12_2961 9374e5d995d45143a861496f98d7fada 441 Pfam PF03471 Transporter associated domain 362 439 1.3E-21 T 12-10-2018 IPR005170 Transporter-associated domain NPD12_2961 9374e5d995d45143a861496f98d7fada 441 SMART SM01091 361 441 2.0E-23 T 12-10-2018 IPR005170 Transporter-associated domain NPD12_2961 9374e5d995d45143a861496f98d7fada 441 Gene3D G3DSA:3.30.465.10 362 441 4.7E-23 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 NPD12_2961 9374e5d995d45143a861496f98d7fada 441 SUPERFAMILY SSF56176 359 439 1.28E-20 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_2961 9374e5d995d45143a861496f98d7fada 441 Pfam PF00571 CBS domain 225 281 2.3E-6 T 12-10-2018 IPR000644 CBS domain NPD12_2961 9374e5d995d45143a861496f98d7fada 441 Gene3D G3DSA:3.10.580.10 205 361 1.4E-51 T 12-10-2018 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 SUPERFAMILY SSF53613 5 262 1.03E-43 T 12-10-2018 IPR029056 Ribokinase-like NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 12 19 4.3E-27 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 82 99 4.3E-27 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 4.3E-27 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 113 127 4.3E-27 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 25 46 4.3E-27 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 56 64 4.3E-27 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 PIRSF PIRSF000513 1 265 7.2E-74 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 2 261 27.34 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 Pfam PF02110 Hydroxyethylthiazole kinase family 6 252 2.2E-60 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_2375 9e3173257a53672e23230ccc2f55e580 265 Gene3D G3DSA:3.40.1190.20 1 265 5.0E-83 T 12-10-2018 IPR029056 Ribokinase-like NPD12_621 8b189610469642ba64d0f2b600a35256 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 59 75 9.0E-13 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 NPD12_621 8b189610469642ba64d0f2b600a35256 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 265 283 9.0E-13 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 NPD12_621 8b189610469642ba64d0f2b600a35256 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 37 53 9.0E-13 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 NPD12_621 8b189610469642ba64d0f2b600a35256 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 78 96 9.0E-13 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 NPD12_621 8b189610469642ba64d0f2b600a35256 380 Gene3D G3DSA:3.40.50.2300 38 356 1.3E-101 T 12-10-2018 NPD12_621 8b189610469642ba64d0f2b600a35256 380 Pfam PF13458 Periplasmic binding protein 36 357 1.0E-76 T 12-10-2018 IPR028081 Leucine-binding protein domain NPD12_621 8b189610469642ba64d0f2b600a35256 380 SUPERFAMILY SSF53822 35 377 2.66E-95 T 12-10-2018 IPR028082 Periplasmic binding protein-like I NPD12_621 8b189610469642ba64d0f2b600a35256 380 Gene3D G3DSA:3.40.50.2300 155 283 1.3E-101 T 12-10-2018 NPD12_2223 9772546e7b246ed2efbcd40b586cad73 404 Gene3D G3DSA:3.90.220.20 14 163 1.1E-71 T 12-10-2018 NPD12_2223 9772546e7b246ed2efbcd40b586cad73 404 Gene3D G3DSA:3.90.220.20 224 361 1.1E-71 T 12-10-2018 NPD12_2223 9772546e7b246ed2efbcd40b586cad73 404 SUPERFAMILY SSF116734 3 218 4.58E-50 T 12-10-2018 NPD12_2223 9772546e7b246ed2efbcd40b586cad73 404 Gene3D G3DSA:1.10.287.1120 164 402 1.1E-71 T 12-10-2018 NPD12_2223 9772546e7b246ed2efbcd40b586cad73 404 Pfam PF01420 Type I restriction modification DNA specificity domain 15 192 5.4E-15 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 NPD12_2223 9772546e7b246ed2efbcd40b586cad73 404 Pfam PF01420 Type I restriction modification DNA specificity domain 223 389 9.8E-6 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 NPD12_2223 9772546e7b246ed2efbcd40b586cad73 404 SUPERFAMILY SSF116734 221 404 9.48E-28 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 TIGRFAM TIGR00763 lon: endopeptidase La 9 769 5.3E-298 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 NPD12_3339 0652968904866b866c43d251574be9cd 773 Hamap MF_01973 Lon protease [lon]. 8 770 69.589 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 NPD12_3339 0652968904866b866c43d251574be9cd 773 Gene3D G3DSA:2.30.130.40 2 113 4.8E-31 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 SUPERFAMILY SSF88697 7 199 8.45E-40 T 12-10-2018 IPR015947 PUA-like superfamily NPD12_3339 0652968904866b866c43d251574be9cd 773 Gene3D G3DSA:1.10.8.60 490 582 5.7E-28 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 SUPERFAMILY SSF54211 593 768 5.69E-53 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3339 0652968904866b866c43d251574be9cd 773 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 674 682 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 NPD12_3339 0652968904866b866c43d251574be9cd 773 SUPERFAMILY SSF52540 307 589 1.82E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3339 0652968904866b866c43d251574be9cd 773 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 487 1.5E-22 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3339 0652968904866b866c43d251574be9cd 773 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 199 1.3E-38 T 12-10-2018 IPR003111 Lon, substrate-binding domain NPD12_3339 0652968904866b866c43d251574be9cd 773 PIRSF PIRSF001174 1 773 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 NPD12_3339 0652968904866b866c43d251574be9cd 773 Gene3D G3DSA:3.30.230.10 591 773 8.5E-80 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_3339 0652968904866b866c43d251574be9cd 773 SMART SM00382 346 493 2.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3339 0652968904866b866c43d251574be9cd 773 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 2.8E-95 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 NPD12_3339 0652968904866b866c43d251574be9cd 773 SMART SM00464 7 200 9.1E-60 T 12-10-2018 IPR003111 Lon, substrate-binding domain NPD12_3339 0652968904866b866c43d251574be9cd 773 Gene3D G3DSA:3.40.50.300 311 489 1.1E-66 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 2.1E-54 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 2.1E-54 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 2.1E-54 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 2.1E-54 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 2.1E-54 T 12-10-2018 NPD12_3339 0652968904866b866c43d251574be9cd 773 Gene3D G3DSA:1.20.58.1480 119 243 8.7E-36 T 12-10-2018 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 SUPERFAMILY SSF63411 1 146 5.86E-62 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 148 35.514 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 Gene3D G3DSA:3.30.1360.80 1 149 3.9E-59 T 12-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 145 7.0E-49 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 146 5.4E-57 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 5.2E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 73 91 5.2E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 5.2E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 5.2E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 114 133 5.2E-40 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_913 c9666de15b63c5e90f4dcd82f5dc3e23 150 PIRSF PIRSF006160 1 150 4.1E-65 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_1153 166cbea2efaef7f19cec849f5d09ea6e 256 Gene3D G3DSA:3.40.50.300 2 252 3.4E-67 T 12-10-2018 NPD12_1153 166cbea2efaef7f19cec849f5d09ea6e 256 SMART SM00382 27 212 3.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1153 166cbea2efaef7f19cec849f5d09ea6e 256 Pfam PF00005 ABC transporter 18 167 2.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1153 166cbea2efaef7f19cec849f5d09ea6e 256 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1153 166cbea2efaef7f19cec849f5d09ea6e 256 SUPERFAMILY SSF52540 3 225 1.54E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3501 40e55ee61933e3b2295faa2a20dc409c 98 Gene3D G3DSA:1.20.58.280 1 98 3.4E-36 T 12-10-2018 NPD12_3501 40e55ee61933e3b2295faa2a20dc409c 98 SUPERFAMILY SSF46973 1 95 8.37E-36 T 12-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 NPD12_3501 40e55ee61933e3b2295faa2a20dc409c 98 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 4 95 6.8E-36 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 NPD12_3501 40e55ee61933e3b2295faa2a20dc409c 98 PIRSF PIRSF000699 1 98 1.4E-37 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 NPD12_3562 275a8415bc2a2cff7fe00c1ea80eacc3 390 PRINTS PR00173 Glutamate-aspartate symporter signature 1 18 7.7E-9 T 12-10-2018 NPD12_3562 275a8415bc2a2cff7fe00c1ea80eacc3 390 PRINTS PR00173 Glutamate-aspartate symporter signature 269 295 7.7E-9 T 12-10-2018 NPD12_3562 275a8415bc2a2cff7fe00c1ea80eacc3 390 PRINTS PR00173 Glutamate-aspartate symporter signature 122 144 7.7E-9 T 12-10-2018 NPD12_3562 275a8415bc2a2cff7fe00c1ea80eacc3 390 Gene3D G3DSA:1.10.3860.10 1 383 6.2E-57 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_3562 275a8415bc2a2cff7fe00c1ea80eacc3 390 SUPERFAMILY SSF118215 6 377 3.79E-85 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_3562 275a8415bc2a2cff7fe00c1ea80eacc3 390 Pfam PF00375 Sodium:dicarboxylate symporter family 6 377 4.9E-79 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 4.4E-14 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 4.4E-14 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 4.4E-14 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.4E-14 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Pfam PF00581 Rhodanese-like domain 461 542 3.9E-11 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 SUPERFAMILY SSF75169 666 811 1.77E-20 T 12-10-2018 IPR027396 DsrEFH-like NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Pfam PF13686 DsrE/DsrF/DrsH-like family 664 816 1.6E-64 T 12-10-2018 IPR032836 DsrE2-like family NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Pfam PF01206 Sulfurtransferase TusA 575 643 4.0E-19 T 12-10-2018 IPR001455 TusA-like domain NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 432 1.4E-9 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 SMART SM00450 454 548 1.3E-15 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Gene3D G3DSA:3.50.50.60 4 342 1.1E-179 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 576 600 - T 12-10-2018 IPR001455 TusA-like domain NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Gene3D G3DSA:3.30.110.40 569 645 1.6E-24 T 12-10-2018 IPR036868 TusA-like domain superfamily NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Gene3D G3DSA:3.50.50.60 115 441 1.1E-179 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 SUPERFAMILY SSF51905 1 318 1.13E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.5E-26 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 5.5E-26 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 5.5E-26 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.5E-26 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 5.5E-26 T 12-10-2018 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 309 1.3E-63 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 SUPERFAMILY SSF55424 325 447 2.92E-29 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Gene3D G3DSA:3.40.1260.10 659 817 1.3E-70 T 12-10-2018 IPR027396 DsrEFH-like NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 SUPERFAMILY SSF52821 433 543 1.44E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 SUPERFAMILY SSF64307 571 644 3.66E-19 T 12-10-2018 IPR036868 TusA-like domain superfamily NPD12_340 306d0af62225c56fee561deeb03a1fe3 817 Gene3D G3DSA:3.40.250.10 456 543 8.0E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_24 e7dff2ac86763a77a5b63f3479885d77 239 SUPERFAMILY SSF142823 1 234 2.48E-79 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 NPD12_24 e7dff2ac86763a77a5b63f3479885d77 239 Pfam PF04029 2-phosphosulpholactate phosphatase 10 231 6.4E-82 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 NPD12_24 e7dff2ac86763a77a5b63f3479885d77 239 Gene3D G3DSA:3.90.1560.10 1 235 2.1E-89 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 NPD12_24 e7dff2ac86763a77a5b63f3479885d77 239 Hamap MF_00490 2-phosphosulfolactate phosphatase [comB]. 5 238 32.498 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 NPD12_3535 47df9baaf90e347739973bef4f304141 618 SUPERFAMILY SSF46600 190 243 1.24E-11 T 12-10-2018 IPR036876 UVR domain superfamily NPD12_3535 47df9baaf90e347739973bef4f304141 618 Gene3D G3DSA:3.40.1440.10 2 100 2.0E-36 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_3535 47df9baaf90e347739973bef4f304141 618 Pfam PF12826 Helix-hairpin-helix motif 570 618 9.1E-10 T 12-10-2018 NPD12_3535 47df9baaf90e347739973bef4f304141 618 SUPERFAMILY SSF47781 530 618 5.72E-19 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_3535 47df9baaf90e347739973bef4f304141 618 Pfam PF02151 UvrB/uvrC motif 214 238 7.5E-6 T 12-10-2018 IPR001943 UVR domain GO:0005515 NPD12_3535 47df9baaf90e347739973bef4f304141 618 Pfam PF01541 GIY-YIG catalytic domain 15 91 2.2E-11 T 12-10-2018 IPR000305 GIY-YIG endonuclease NPD12_3535 47df9baaf90e347739973bef4f304141 618 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 598 2.0E-178 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 NPD12_3535 47df9baaf90e347739973bef4f304141 618 SMART SM00465 14 96 3.5E-27 T 12-10-2018 IPR000305 GIY-YIG endonuclease NPD12_3535 47df9baaf90e347739973bef4f304141 618 Gene3D G3DSA:1.10.150.20 559 617 1.4E-18 T 12-10-2018 NPD12_3535 47df9baaf90e347739973bef4f304141 618 Gene3D G3DSA:3.30.420.340 379 558 4.4E-55 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily NPD12_3535 47df9baaf90e347739973bef4f304141 618 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 386 551 2.5E-53 T 12-10-2018 IPR001162 UvrC family homology region NPD12_3535 47df9baaf90e347739973bef4f304141 618 SUPERFAMILY SSF82771 13 98 3.66E-25 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_3535 47df9baaf90e347739973bef4f304141 618 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 616 28.232 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 SUPERFAMILY SSF63520 61 168 1.83E-28 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 Gene3D G3DSA:2.30.24.10 1 67 2.7E-19 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 Pfam PF03123 CAT RNA binding domain 4 58 1.8E-18 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 SMART SM01061 4 61 8.8E-23 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 Gene3D G3DSA:1.10.1790.10 173 274 6.8E-23 T 12-10-2018 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 Gene3D G3DSA:1.10.1790.10 68 167 5.0E-31 T 12-10-2018 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 SUPERFAMILY SSF63520 175 271 3.27E-25 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 SUPERFAMILY SSF50151 4 54 1.83E-14 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 Pfam PF00874 PRD domain 183 271 7.3E-23 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_2788 9a8e12b5d2826bfdf5239056ffc082c2 275 Pfam PF00874 PRD domain 77 163 9.0E-25 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_2156 190bbd9dd3ad189802fb02f053904aeb 245 Gene3D G3DSA:1.10.10.10 2 74 9.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2156 190bbd9dd3ad189802fb02f053904aeb 245 SUPERFAMILY SSF53697 82 243 1.42E-24 T 12-10-2018 NPD12_2156 190bbd9dd3ad189802fb02f053904aeb 245 Pfam PF01380 SIS domain 112 212 4.5E-16 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_2156 190bbd9dd3ad189802fb02f053904aeb 245 SUPERFAMILY SSF46689 3 70 2.15E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2156 190bbd9dd3ad189802fb02f053904aeb 245 Gene3D G3DSA:3.40.50.10490 81 245 4.7E-25 T 12-10-2018 NPD12_2156 190bbd9dd3ad189802fb02f053904aeb 245 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 70 7.6E-12 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_1795 5d78da09f567281d13d22c8c775cde43 221 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 217 36.184 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 NPD12_1795 5d78da09f567281d13d22c8c775cde43 221 Pfam PF04055 Radical SAM superfamily 27 195 3.9E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_1795 5d78da09f567281d13d22c8c775cde43 221 Gene3D G3DSA:3.20.20.70 2 214 1.9E-37 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1795 5d78da09f567281d13d22c8c775cde43 221 PIRSF PIRSF000370 1 220 1.2E-55 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 NPD12_1795 5d78da09f567281d13d22c8c775cde43 221 Pfam PF13394 4Fe-4S single cluster domain 24 109 6.4E-14 T 12-10-2018 NPD12_1795 5d78da09f567281d13d22c8c775cde43 221 SUPERFAMILY SSF102114 24 203 2.09E-18 T 12-10-2018 NPD12_1795 5d78da09f567281d13d22c8c775cde43 221 TIGRFAM TIGR03963 rSAM_QueE_Clost: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 221 1.7E-111 T 12-10-2018 IPR023868 7-carboxy-7-deazaguanine synthase, Clostridial form KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 SMART SM00387 368 473 5.3E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 Gene3D G3DSA:3.30.565.10 325 471 6.9E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 SUPERFAMILY SSF55874 329 462 1.57E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 SUPERFAMILY SSF158472 193 242 6.28E-9 T 12-10-2018 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 SUPERFAMILY SSF47384 245 321 3.53E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 SMART SM00388 258 325 1.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 Gene3D G3DSA:1.10.287.130 250 324 3.0E-18 T 12-10-2018 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 Gene3D G3DSA:1.20.1480.50 153 249 5.2E-15 T 12-10-2018 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 321 7.5E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 SMART SM00304 191 243 6.8E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 469 3.2E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_785 01ca6cdc43cb188c7bde3d3fc7b6b3e1 473 Pfam PF00672 HAMP domain 193 239 4.7E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_612 6f0ae142dc3da4c24a7a5c0c78a0df7c 471 Gene3D G3DSA:3.40.50.12090 155 244 1.7E-8 T 12-10-2018 NPD12_612 6f0ae142dc3da4c24a7a5c0c78a0df7c 471 Gene3D G3DSA:3.40.50.12090 55 151 1.4E-9 T 12-10-2018 NPD12_612 6f0ae142dc3da4c24a7a5c0c78a0df7c 471 Pfam PF04122 Putative cell wall binding repeat 2 33 119 9.4E-21 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_612 6f0ae142dc3da4c24a7a5c0c78a0df7c 471 Pfam PF04122 Putative cell wall binding repeat 2 132 217 1.0E-21 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_612 6f0ae142dc3da4c24a7a5c0c78a0df7c 471 Pfam PF04122 Putative cell wall binding repeat 2 226 313 2.0E-17 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_612 6f0ae142dc3da4c24a7a5c0c78a0df7c 471 Pfam PF16800 IseA DL-endopeptidase inhibitor 323 466 4.5E-42 T 12-10-2018 IPR031841 DL-endopeptidase inhibitor IseA NPD12_612 6f0ae142dc3da4c24a7a5c0c78a0df7c 471 Gene3D G3DSA:3.10.450.420 323 468 1.0E-6 T 12-10-2018 NPD12_2268 9601b243598b1d2053dca78a7f3a3822 162 SUPERFAMILY SSF46955 5 54 1.65E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_2268 9601b243598b1d2053dca78a7f3a3822 162 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 53 3.0E-11 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 NPD12_2268 9601b243598b1d2053dca78a7f3a3822 162 Pfam PF12728 Helix-turn-helix domain 5 54 3.1E-12 T 12-10-2018 NPD12_2268 9601b243598b1d2053dca78a7f3a3822 162 Gene3D G3DSA:1.10.1660.10 3 54 7.4E-9 T 12-10-2018 NPD12_2725 b813bca886b1a96b9952760f55530291 149 Pfam PF04892 VanZ like family 11 140 3.4E-25 T 12-10-2018 IPR006976 VanZ-like NPD12_2725 b813bca886b1a96b9952760f55530291 149 PIRSF PIRSF019083 1 149 2.6E-39 T 12-10-2018 IPR016747 Phosphotransbutyrylase NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 SUPERFAMILY SSF63411 261 522 2.85E-64 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 Pfam PF00675 Insulinase (Peptidase family M16) 59 136 8.2E-7 T 12-10-2018 IPR011765 Peptidase M16, N-terminal NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 Gene3D G3DSA:3.30.830.10 531 780 2.3E-153 T 12-10-2018 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 Gene3D G3DSA:3.30.830.10 497 949 2.3E-153 T 12-10-2018 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 Pfam PF08367 Peptidase M16C associated 465 713 5.3E-79 T 12-10-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 Pfam PF05193 Peptidase M16 inactive domain 207 389 6.5E-23 T 12-10-2018 IPR007863 Peptidase M16, C-terminal NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 Gene3D G3DSA:3.30.830.10 256 487 3.4E-69 T 12-10-2018 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 SMART SM01264 464 714 2.4E-101 T 12-10-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 SUPERFAMILY SSF63411 524 772 2.93E-66 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 SUPERFAMILY SSF63411 8 252 1.03E-50 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 Gene3D G3DSA:3.30.830.10 1 255 1.1E-89 T 12-10-2018 NPD12_3439 9ca43ff17cb3b111c618a81c16d564ad 975 SUPERFAMILY SSF63411 783 974 2.62E-37 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_1283 673362c5255848f993952af06f3038aa 388 SUPERFAMILY SSF53187 2 387 2.6E-79 T 12-10-2018 NPD12_1283 673362c5255848f993952af06f3038aa 388 SUPERFAMILY SSF55031 183 289 1.03E-26 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain NPD12_1283 673362c5255848f993952af06f3038aa 388 Pfam PF07687 Peptidase dimerisation domain 185 277 1.6E-7 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_1283 673362c5255848f993952af06f3038aa 388 Gene3D G3DSA:3.30.70.360 180 294 1.6E-133 T 12-10-2018 NPD12_1283 673362c5255848f993952af06f3038aa 388 PIRSF PIRSF005962 1 388 1.3E-128 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 NPD12_1283 673362c5255848f993952af06f3038aa 388 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 374 7.3E-108 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 NPD12_1283 673362c5255848f993952af06f3038aa 388 Gene3D G3DSA:3.40.630.10 15 371 1.6E-133 T 12-10-2018 NPD12_1283 673362c5255848f993952af06f3038aa 388 Pfam PF01546 Peptidase family M20/M25/M40 72 382 9.4E-29 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 SUPERFAMILY SSF51735 3 164 3.94E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 416 3.0E-53 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 Gene3D G3DSA:3.40.50.720 1 166 2.1E-58 T 12-10-2018 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 Gene3D G3DSA:3.90.110.10 167 441 1.7E-106 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 1.5E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 1.5E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 1.5E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 1.5E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 1.5E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 1.5E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 1.5E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 Pfam PF02056 Family 4 glycosyl hydrolase 6 184 2.9E-66 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 12-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 NPD12_445 e2612ad341f2bcfbbaf593211a94711b 441 SUPERFAMILY SSF56327 168 441 1.39E-96 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_1973 de7083dedfc58ef3c1f7a0275968033e 477 SUPERFAMILY SSF116726 393 473 6.15E-12 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1973 de7083dedfc58ef3c1f7a0275968033e 477 Pfam PF02080 TrkA-C domain 407 473 1.5E-13 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 NPD12_1973 de7083dedfc58ef3c1f7a0275968033e 477 Gene3D G3DSA:1.20.1530.20 5 397 1.2E-64 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_1973 de7083dedfc58ef3c1f7a0275968033e 477 Gene3D G3DSA:3.30.70.1450 398 474 9.1E-14 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1973 de7083dedfc58ef3c1f7a0275968033e 477 Pfam PF00999 Sodium/hydrogen exchanger family 10 385 6.1E-58 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 NPD12_62 ca42c65538a811ff28e6fecc83bfbc0c 315 Gene3D G3DSA:3.40.50.720 97 282 5.6E-80 T 12-10-2018 NPD12_62 ca42c65538a811ff28e6fecc83bfbc0c 315 SUPERFAMILY SSF52283 32 119 1.06E-12 T 12-10-2018 NPD12_62 ca42c65538a811ff28e6fecc83bfbc0c 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 12 310 1.0E-11 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 NPD12_62 ca42c65538a811ff28e6fecc83bfbc0c 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 277 1.3E-51 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 NPD12_62 ca42c65538a811ff28e6fecc83bfbc0c 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site NPD12_62 ca42c65538a811ff28e6fecc83bfbc0c 315 SUPERFAMILY SSF51735 98 279 7.53E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_62 ca42c65538a811ff28e6fecc83bfbc0c 315 Gene3D G3DSA:3.40.50.720 31 307 5.6E-80 T 12-10-2018 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 TIGRFAM TIGR01193 bacteriocin_ABC: ABC-type bacteriocin transporter 13 717 1.0E-214 T 12-10-2018 IPR005897 Peptidase C39, ABC-type bacteriocin transporter GO:0008234|GO:0016020|GO:0022885|GO:0043213 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 Pfam PF00664 ABC transporter transmembrane region 168 437 6.1E-50 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 ProSitePatterns PS00211 ABC transporters family signature. 622 636 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 Gene3D G3DSA:1.20.1560.10 153 469 5.0E-91 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 Pfam PF03412 Peptidase C39 family 8 142 1.6E-40 T 12-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 SMART SM00382 510 695 2.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 Pfam PF00005 ABC transporter 501 650 3.0E-38 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 SUPERFAMILY SSF52540 476 720 2.5E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 Gene3D G3DSA:3.40.50.300 475 724 3.5E-94 T 12-10-2018 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 SUPERFAMILY SSF90123 151 463 1.44E-66 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1405 cee4aaf7fbd2c8a92c2c87f84c20d441 740 Gene3D G3DSA:3.90.70.10 1 151 5.9E-53 T 12-10-2018 NPD12_2280 241d2e7bd95425367bfe5430e7c2dee2 340 Pfam PF16912 Glucose dehydrogenase C-terminus 143 339 2.4E-12 T 12-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 NPD12_2280 241d2e7bd95425367bfe5430e7c2dee2 340 Gene3D G3DSA:3.90.180.10 27 330 2.2E-63 T 12-10-2018 NPD12_2280 241d2e7bd95425367bfe5430e7c2dee2 340 SUPERFAMILY SSF51735 137 305 8.55E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2280 241d2e7bd95425367bfe5430e7c2dee2 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 130 5.7E-23 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 NPD12_2280 241d2e7bd95425367bfe5430e7c2dee2 340 SUPERFAMILY SSF50129 1 174 3.93E-31 T 12-10-2018 IPR011032 GroES-like superfamily NPD12_2280 241d2e7bd95425367bfe5430e7c2dee2 340 Gene3D G3DSA:3.40.50.720 149 289 2.2E-63 T 12-10-2018 NPD12_2973 81deb165ddba35281e607e9a70081622 147 Gene3D G3DSA:1.10.10.2520 3 96 6.4E-15 T 12-10-2018 NPD12_2973 81deb165ddba35281e607e9a70081622 147 Pfam PF07486 Cell Wall Hydrolase 19 138 1.5E-18 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 SUPERFAMILY SSF158499 121 187 9.29E-18 T 12-10-2018 IPR034829 DnaD-like domain superfamily NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 SUPERFAMILY SSF158499 211 274 3.27E-16 T 12-10-2018 IPR034829 DnaD-like domain superfamily NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 PIRSF PIRSF033722 1 328 1.2E-149 T 12-10-2018 IPR017019 Predicted DNA replication protein, bacterial NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 Pfam PF07261 Replication initiation and membrane attachment 123 195 2.6E-25 T 12-10-2018 IPR006343 DnaD domain NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 Pfam PF07261 Replication initiation and membrane attachment 223 278 2.3E-14 T 12-10-2018 IPR006343 DnaD domain NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 122 192 3.0E-17 T 12-10-2018 IPR006343 DnaD domain NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 218 278 4.9E-17 T 12-10-2018 IPR006343 DnaD domain NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 Gene3D G3DSA:1.10.10.630 207 279 1.5E-13 T 12-10-2018 IPR034829 DnaD-like domain superfamily NPD12_77 7a592c5830ec1d073cd8aab347d04f89 328 Gene3D G3DSA:1.10.10.630 116 192 1.3E-18 T 12-10-2018 IPR034829 DnaD-like domain superfamily NPD12_1799 e6b2af9ea36d11215a0a54fcb6b7aa00 318 Gene3D G3DSA:1.10.287.950 23 318 3.1E-55 T 12-10-2018 NPD12_1799 e6b2af9ea36d11215a0a54fcb6b7aa00 318 SUPERFAMILY SSF58104 40 308 9.42E-56 T 12-10-2018 NPD12_1799 e6b2af9ea36d11215a0a54fcb6b7aa00 318 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 80 109 3.2E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_1799 e6b2af9ea36d11215a0a54fcb6b7aa00 318 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 183 212 3.2E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_1799 e6b2af9ea36d11215a0a54fcb6b7aa00 318 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 154 181 3.2E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_1799 e6b2af9ea36d11215a0a54fcb6b7aa00 318 SMART SM00283 56 314 3.3E-40 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1799 e6b2af9ea36d11215a0a54fcb6b7aa00 318 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 130 284 8.2E-37 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 474 188.212 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 SUPERFAMILY SSF52540 146 424 1.75E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 Pfam PF07498 Rho termination factor, N-terminal domain 5 39 4.8E-11 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 SUPERFAMILY SSF50249 101 170 2.51E-6 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 Pfam PF07497 Rho termination factor, RNA-binding domain 109 181 1.0E-31 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 SMART SM00959 5 47 1.9E-11 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 SMART SM00382 223 408 4.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 SUPERFAMILY SSF68912 5 39 2.82E-6 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 472 1.8E-176 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 Gene3D G3DSA:1.10.720.10 4 40 1.9E-5 T 12-10-2018 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 Gene3D G3DSA:3.40.50.300 187 472 8.9E-119 T 12-10-2018 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 Gene3D G3DSA:2.40.50.140 60 184 1.1E-36 T 12-10-2018 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 SMART SM00357 109 174 3.4E-14 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 NPD12_288 fd3c4e8e4787ede3e0177beb306c7f05 481 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 213 416 1.2E-18 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_1303 af3db84d8c176cd568a5d6b14bb6c666 339 Gene3D G3DSA:3.40.50.300 1 237 7.3E-76 T 12-10-2018 NPD12_1303 af3db84d8c176cd568a5d6b14bb6c666 339 SUPERFAMILY SSF52540 4 243 8.83E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1303 af3db84d8c176cd568a5d6b14bb6c666 339 SMART SM00382 28 211 1.3E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1303 af3db84d8c176cd568a5d6b14bb6c666 339 SUPERFAMILY SSF50331 237 338 3.34E-13 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal NPD12_1303 af3db84d8c176cd568a5d6b14bb6c666 339 Pfam PF00005 ABC transporter 19 161 8.0E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1303 af3db84d8c176cd568a5d6b14bb6c666 339 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1736 2c1d62e3b988463a0edd8482da81265e 307 SUPERFAMILY SSF52151 7 304 3.4E-35 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase NPD12_1736 2c1d62e3b988463a0edd8482da81265e 307 Pfam PF01734 Patatin-like phospholipase 7 199 9.0E-27 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 NPD12_1736 2c1d62e3b988463a0edd8482da81265e 307 Gene3D G3DSA:3.40.1090.10 5 121 1.7E-19 T 12-10-2018 NPD12_1736 2c1d62e3b988463a0edd8482da81265e 307 Gene3D G3DSA:3.40.1090.10 122 296 1.5E-17 T 12-10-2018 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.2E-35 T 12-10-2018 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.2E-35 T 12-10-2018 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.2E-35 T 12-10-2018 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.2E-35 T 12-10-2018 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.2E-35 T 12-10-2018 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 298 2.6E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 5 309 5.2E-113 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 Gene3D G3DSA:3.50.50.60 8 308 6.5E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 6.9E-71 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 Gene3D G3DSA:3.50.50.60 121 249 6.5E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1448 21df6b16acc06eadcc1cd674803d89bd 313 SUPERFAMILY SSF51905 1 307 7.78E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 Pfam PF08544 GHMP kinases C terminal 196 260 5.0E-6 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 SUPERFAMILY SSF55060 157 277 1.58E-29 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 Hamap MF_00384 Homoserine kinase [thrB]. 4 293 29.566 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 SUPERFAMILY SSF54211 1 146 4.63E-32 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 PIRSF PIRSF000676 1 295 1.8E-86 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 81 92 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 TIGRFAM TIGR00191 thrB: homoserine kinase 2 292 7.7E-84 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 PRINTS PR00958 Homoserine kinase signature 9 24 1.6E-38 T 12-10-2018 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 PRINTS PR00958 Homoserine kinase signature 122 135 1.6E-38 T 12-10-2018 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 PRINTS PR00958 Homoserine kinase signature 240 255 1.6E-38 T 12-10-2018 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 PRINTS PR00958 Homoserine kinase signature 88 103 1.6E-38 T 12-10-2018 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 PRINTS PR00958 Homoserine kinase signature 161 178 1.6E-38 T 12-10-2018 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 Pfam PF00288 GHMP kinases N terminal domain 74 135 6.6E-12 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 Gene3D G3DSA:3.30.70.890 159 282 2.4E-37 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily NPD12_1878 907262d38fbdaaf810331cf1163e4652 297 Gene3D G3DSA:3.30.230.10 1 158 1.2E-50 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 Gene3D G3DSA:2.40.100.10 1 167 4.3E-57 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 2.3E-19 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 2.3E-19 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 105 117 2.3E-19 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 2.3E-19 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 5 156 6.2E-48 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 SUPERFAMILY SSF50891 4 159 6.14E-53 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily NPD12_32 52b7c91072b9afdba5dc551e7659b6f2 172 PIRSF PIRSF001467 3 162 1.4E-39 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 NPD12_1313 9e6a145de4782eef33eef23930176370 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 219 286 3.3E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1313 9e6a145de4782eef33eef23930176370 477 SUPERFAMILY SSF55874 275 445 3.54E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1313 9e6a145de4782eef33eef23930176370 477 Gene3D G3DSA:3.30.565.10 293 454 8.5E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1313 9e6a145de4782eef33eef23930176370 477 Gene3D G3DSA:1.10.287.130 200 288 3.3E-18 T 12-10-2018 NPD12_1313 9e6a145de4782eef33eef23930176370 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 8.8E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1313 9e6a145de4782eef33eef23930176370 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 8.8E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1313 9e6a145de4782eef33eef23930176370 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 8.8E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1313 9e6a145de4782eef33eef23930176370 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 398 8.8E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1313 9e6a145de4782eef33eef23930176370 477 SUPERFAMILY SSF47384 206 286 2.94E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1313 9e6a145de4782eef33eef23930176370 477 SMART SM00387 332 446 1.2E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1313 9e6a145de4782eef33eef23930176370 477 SMART SM00388 218 286 3.5E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1313 9e6a145de4782eef33eef23930176370 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 445 1.4E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2122 553fcc3efc9983b49036ae0e24ac4cd7 268 SUPERFAMILY SSF55136 126 265 9.42E-15 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2122 553fcc3efc9983b49036ae0e24ac4cd7 268 Gene3D G3DSA:1.10.1660.10 4 114 1.7E-24 T 12-10-2018 NPD12_2122 553fcc3efc9983b49036ae0e24ac4cd7 268 Pfam PF13411 MerR HTH family regulatory protein 6 74 1.1E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2122 553fcc3efc9983b49036ae0e24ac4cd7 268 Gene3D G3DSA:3.20.80.10 118 267 5.4E-6 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2122 553fcc3efc9983b49036ae0e24ac4cd7 268 SMART SM00422 6 75 1.9E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2122 553fcc3efc9983b49036ae0e24ac4cd7 268 SUPERFAMILY SSF46955 4 108 1.1E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_2813 34d98e6be700a8849cd652f695a39ec5 138 Pfam PF00258 Flavodoxin 6 130 2.1E-17 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 NPD12_2813 34d98e6be700a8849cd652f695a39ec5 138 SUPERFAMILY SSF52218 3 137 1.65E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2813 34d98e6be700a8849cd652f695a39ec5 138 TIGRFAM TIGR01753 flav_short: flavodoxin 4 138 5.5E-46 T 12-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 NPD12_2813 34d98e6be700a8849cd652f695a39ec5 138 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 12-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 NPD12_2813 34d98e6be700a8849cd652f695a39ec5 138 Gene3D G3DSA:3.40.50.360 4 138 5.3E-37 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1323 8c2eae544de8307b7523a3365193bcf5 504 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 48 487 1.5E-146 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 NPD12_1323 8c2eae544de8307b7523a3365193bcf5 504 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 10 487 2.2E-177 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 NPD12_771 6bae1a13ed26e619e7887ab82510035b 170 Hamap MF_01515 UPF0316 protein . 2 170 27.456 T 12-10-2018 IPR022930 Protein of unknown function UPF0316 NPD12_771 6bae1a13ed26e619e7887ab82510035b 170 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 113 164 1.4E-7 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 SUPERFAMILY SSF53067 8 144 1.4E-41 T 12-10-2018 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 65 88 1.1E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 183 203 1.1E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 296 322 1.1E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 128 147 1.1E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 45 63 1.1E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 Gene3D G3DSA:3.30.420.40 10 323 3.1E-134 T 12-10-2018 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 SUPERFAMILY SSF53067 145 327 5.71E-52 T 12-10-2018 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 Gene3D G3DSA:3.30.420.40 150 313 3.1E-134 T 12-10-2018 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 331 4.5E-156 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 Pfam PF06723 MreB/Mbl protein 8 331 2.5E-156 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 NPD12_3108 35e24c6e6c3d7f63d45559f468227ba8 336 Gene3D G3DSA:3.90.640.10 182 255 3.1E-134 T 12-10-2018 NPD12_450 bba0e30b8274b5f3f0abc53bd6cafdb1 143 SUPERFAMILY SSF46785 2 137 1.79E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_450 bba0e30b8274b5f3f0abc53bd6cafdb1 143 Gene3D G3DSA:1.10.10.10 1 143 7.0E-57 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_450 bba0e30b8274b5f3f0abc53bd6cafdb1 143 Pfam PF02082 Transcriptional regulator 1 81 2.4E-24 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_1859 9ac4f7f202ab1e0ee13bd5ce4439d2e1 62 Pfam PF12841 YvrJ protein family 8 42 3.2E-16 T 12-10-2018 IPR024419 Protein of unknown function YvrJ NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 1.7E-11 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 PIRSF PIRSF003095 1 430 3.0E-129 T 12-10-2018 IPR005215 Trigger factor GO:0015031 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 424 8.1E-44 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 Gene3D G3DSA:3.30.70.1050 1 112 6.6E-33 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 Gene3D G3DSA:1.10.3120.10 114 427 3.5E-85 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 SUPERFAMILY SSF54534 89 243 6.09E-31 T 12-10-2018 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 6.8E-43 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 TIGRFAM TIGR00115 tig: trigger factor 13 423 1.6E-136 T 12-10-2018 IPR005215 Trigger factor GO:0015031 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 SUPERFAMILY SSF109998 250 427 3.14E-41 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 SUPERFAMILY SSF102735 1 132 1.7E-40 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 Gene3D G3DSA:3.10.50.40 151 248 3.5E-85 T 12-10-2018 NPD12_3343 e42fb18811259fe634bd18a840b343e5 430 Hamap MF_00303 Trigger factor [tig]. 1 429 22.911 T 12-10-2018 IPR005215 Trigger factor GO:0015031 NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 Pfam PF00581 Rhodanese-like domain 164 269 7.1E-10 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 Pfam PF00581 Rhodanese-like domain 6 126 5.0E-21 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 SUPERFAMILY SSF52821 4 136 1.96E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 SMART SM00450 160 274 4.6E-13 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 SMART SM00450 5 131 1.3E-18 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 SUPERFAMILY SSF52821 158 277 7.6E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 Gene3D G3DSA:3.40.250.10 1 147 5.6E-40 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_981 053b91f1f5b475d1e2360db5bc17582d 279 Gene3D G3DSA:3.40.250.10 162 279 1.0E-26 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1375 3b791f6a3684d70b99ed851fca694bbd 447 SUPERFAMILY SSF55874 311 429 1.44E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1375 3b791f6a3684d70b99ed851fca694bbd 447 Gene3D G3DSA:3.30.565.10 295 446 5.0E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1375 3b791f6a3684d70b99ed851fca694bbd 447 Pfam PF14501 GHKL domain 340 444 1.1E-15 T 12-10-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain NPD12_1378 179eafae9676469bce2b6ac66205b740 628 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 19 361 1.2E-83 T 12-10-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain NPD12_1378 179eafae9676469bce2b6ac66205b740 628 SUPERFAMILY SSF51695 374 603 5.23E-67 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 NPD12_1378 179eafae9676469bce2b6ac66205b740 628 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 379 597 1.2E-33 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 NPD12_1378 179eafae9676469bce2b6ac66205b740 628 Gene3D G3DSA:3.20.20.190 365 608 8.8E-70 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 NPD12_1224 fc3934314c81c964829563cdb2bc3808 145 SUPERFAMILY SSF55729 1 141 9.14E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1224 fc3934314c81c964829563cdb2bc3808 145 Pfam PF13673 Acetyltransferase (GNAT) domain 37 136 4.0E-11 T 12-10-2018 IPR000182 GNAT domain NPD12_1224 fc3934314c81c964829563cdb2bc3808 145 Gene3D G3DSA:3.40.630.30 1 140 7.9E-21 T 12-10-2018 NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 SUPERFAMILY SSF52540 430 633 2.01E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 Pfam PF00488 MutS domain V 463 620 5.8E-27 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 SUPERFAMILY SSF48334 126 196 7.85E-7 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 SMART SM00534 459 636 2.2E-12 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 Gene3D G3DSA:1.10.1420.10 117 203 4.4E-5 T 12-10-2018 NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 Gene3D G3DSA:3.40.50.300 423 636 6.9E-49 T 12-10-2018 NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 PIRSF PIRSF037677 407 634 1.4E-28 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 NPD12_1754 82cb739dadebdc371dcd67ba3b70bb1e 637 PIRSF PIRSF037677 119 211 0.0016 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 Pfam PF00376 MerR family regulatory protein 7 43 1.1E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 Gene3D G3DSA:1.10.1660.10 1 122 1.2E-19 T 12-10-2018 NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 Gene3D G3DSA:1.10.1660.10 123 250 3.7E-20 T 12-10-2018 NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 SUPERFAMILY SSF46955 127 211 3.55E-17 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 Pfam PF13411 MerR HTH family regulatory protein 130 194 3.9E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 SMART SM00422 5 70 4.1E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 SMART SM00422 127 195 1.3E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_894 f702d43e621ce8ccf11a6478d976d2f5 254 SUPERFAMILY SSF46955 5 109 2.93E-13 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_690 f2a9ab517dc4237c6c97c65a34efe5c4 345 Pfam PF04055 Radical SAM superfamily 7 153 9.8E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_690 f2a9ab517dc4237c6c97c65a34efe5c4 345 Gene3D G3DSA:3.20.20.70 1 334 1.1E-54 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_690 f2a9ab517dc4237c6c97c65a34efe5c4 345 Pfam PF13353 4Fe-4S single cluster domain 4 129 4.5E-12 T 12-10-2018 NPD12_690 f2a9ab517dc4237c6c97c65a34efe5c4 345 SUPERFAMILY SSF102114 3 298 1.44E-37 T 12-10-2018 NPD12_2300 29ba9f25fcf02b5d9c7759410a4e381d 265 Pfam PF13411 MerR HTH family regulatory protein 3 64 6.3E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2300 29ba9f25fcf02b5d9c7759410a4e381d 265 Gene3D G3DSA:1.10.1660.10 1 130 1.1E-14 T 12-10-2018 NPD12_2300 29ba9f25fcf02b5d9c7759410a4e381d 265 SUPERFAMILY SSF46955 3 82 1.69E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_2300 29ba9f25fcf02b5d9c7759410a4e381d 265 SMART SM00422 3 71 1.8E-4 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_3190 97e20d8abd4f577b4dfada57a240c2ae 174 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 170 4.7E-59 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 NPD12_3190 97e20d8abd4f577b4dfada57a240c2ae 174 SUPERFAMILY SSF53271 6 173 6.82E-56 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_3190 97e20d8abd4f577b4dfada57a240c2ae 174 Pfam PF00156 Phosphoribosyl transferase domain 13 158 7.2E-29 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_3190 97e20d8abd4f577b4dfada57a240c2ae 174 Gene3D G3DSA:3.40.50.2020 1 174 1.0E-63 T 12-10-2018 NPD12_656 cd4f9e220aea89c97ddd56139f3705f8 452 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 69 452 1.3E-111 T 12-10-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component NPD12_656 cd4f9e220aea89c97ddd56139f3705f8 452 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 68 421 1.8E-50 T 12-10-2018 IPR003776 YcaO-like domain NPD12_656 cd4f9e220aea89c97ddd56139f3705f8 452 Gene3D G3DSA:2.40.50.820 101 193 6.6E-16 T 12-10-2018 NPD12_656 cd4f9e220aea89c97ddd56139f3705f8 452 Gene3D G3DSA:3.30.160.660 228 370 6.6E-16 T 12-10-2018 NPD12_656 cd4f9e220aea89c97ddd56139f3705f8 452 Gene3D G3DSA:1.10.490.140 83 421 6.6E-16 T 12-10-2018 NPD12_2867 1aa624f4dbc0532d6f5be09251820115 456 PIRSF PIRSF006603 1 451 1.2E-88 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2867 1aa624f4dbc0532d6f5be09251820115 456 Pfam PF01554 MatE 244 404 1.5E-17 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2867 1aa624f4dbc0532d6f5be09251820115 456 Pfam PF01554 MatE 23 184 1.6E-27 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2867 1aa624f4dbc0532d6f5be09251820115 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 416 1.2E-57 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_3482 f8dcdc43e36f06191e3498f1c53aa1bf 709 Gene3D G3DSA:3.40.50.300 202 378 1.5E-13 T 12-10-2018 NPD12_3482 f8dcdc43e36f06191e3498f1c53aa1bf 709 SUPERFAMILY SSF52540 203 703 1.63E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3482 f8dcdc43e36f06191e3498f1c53aa1bf 709 Gene3D G3DSA:3.40.50.300 380 532 2.5E-10 T 12-10-2018 NPD12_3482 f8dcdc43e36f06191e3498f1c53aa1bf 709 Gene3D G3DSA:3.40.50.300 558 709 9.6E-34 T 12-10-2018 NPD12_3482 f8dcdc43e36f06191e3498f1c53aa1bf 709 Pfam PF13245 AAA domain 218 531 1.2E-12 T 12-10-2018 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 SMART SM00487 14 211 3.7E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Gene3D G3DSA:3.40.50.300 202 333 1.8E-40 T 12-10-2018 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 6 587 3.2E-233 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 SMART SM00956 406 509 5.0E-44 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Gene3D G3DSA:3.40.50.300 1 201 1.1E-76 T 12-10-2018 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Gene3D G3DSA:1.10.10.10 334 513 1.3E-50 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Gene3D G3DSA:1.10.150.80 514 594 9.2E-26 T 12-10-2018 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 SUPERFAMILY SSF46785 397 539 2.99E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 456 1.5E-149 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Pfam PF16124 RecQ zinc-binding 336 398 2.5E-16 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Pfam PF14493 Helix-turn-helix domain 614 701 1.9E-25 T 12-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 SMART SM00490 243 324 6.9E-28 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Pfam PF09382 RQC domain 402 512 8.1E-35 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Pfam PF00570 HRDC domain 518 584 1.1E-22 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Pfam PF00270 DEAD/DEAH box helicase 20 183 1.4E-20 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 Pfam PF00271 Helicase conserved C-terminal domain 218 323 6.3E-19 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 SUPERFAMILY SSF47819 516 598 5.45E-24 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 SMART SM00341 514 594 9.4E-17 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 NPD12_1185 407b9a47670c7d298ae836685097fbcb 709 SUPERFAMILY SSF52540 58 345 2.55E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 SUPERFAMILY SSF88659 201 275 4.58E-23 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Gene3D G3DSA:1.10.220.120 10 73 1.3E-11 T 12-10-2018 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 SUPERFAMILY SSF88659 258 360 1.4E-30 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Pfam PF04542 Sigma-70 region 2 128 197 2.9E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 321 347 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Gene3D G3DSA:1.10.10.10 201 276 1.4E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Pfam PF04545 Sigma-70, region 4 296 349 4.2E-20 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 SUPERFAMILY SSF88946 89 198 8.77E-54 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Gene3D G3DSA:1.10.10.10 278 361 3.3E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Pfam PF03979 Sigma-70 factor, region 1.1 15 77 3.0E-16 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Gene3D G3DSA:1.10.601.10 88 121 1.3E-11 T 12-10-2018 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Gene3D G3DSA:1.10.601.10 122 200 5.2E-51 T 12-10-2018 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 13 361 34.559 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 124 360 7.3E-124 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Pfam PF00140 Sigma-70 factor, region 1.2 90 121 7.6E-18 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 126 349 6.5E-40 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 PRINTS PR00046 Major sigma-70 factor signature 321 336 2.1E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 PRINTS PR00046 Major sigma-70 factor signature 300 312 2.1E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 PRINTS PR00046 Major sigma-70 factor signature 176 184 2.1E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 PRINTS PR00046 Major sigma-70 factor signature 152 165 2.1E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 PRINTS PR00046 Major sigma-70 factor signature 336 347 2.1E-32 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 152 165 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2986 082456d000224d4d76d6e10bbcaacf80 361 Pfam PF04539 Sigma-70 region 3 207 283 2.6E-31 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 NPD12_1456 37415096f10b187915c40b5b047ead73 239 Gene3D G3DSA:3.30.200.20 1 115 3.9E-41 T 12-10-2018 NPD12_1456 37415096f10b187915c40b5b047ead73 239 Gene3D G3DSA:3.90.1200.10 117 235 1.3E-39 T 12-10-2018 NPD12_1456 37415096f10b187915c40b5b047ead73 239 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 33 234 2.1E-73 T 12-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 NPD12_1456 37415096f10b187915c40b5b047ead73 239 SUPERFAMILY SSF56112 3 233 2.08E-49 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_339 df542cf2874494c501c8efc435a1d6e7 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 3.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_339 df542cf2874494c501c8efc435a1d6e7 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 3.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_339 df542cf2874494c501c8efc435a1d6e7 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 3.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_339 df542cf2874494c501c8efc435a1d6e7 93 SMART SM00418 13 92 5.9E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_339 df542cf2874494c501c8efc435a1d6e7 93 Gene3D G3DSA:1.10.10.10 1 93 3.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_339 df542cf2874494c501c8efc435a1d6e7 93 Pfam PF12840 Helix-turn-helix domain 12 70 7.4E-12 T 12-10-2018 NPD12_339 df542cf2874494c501c8efc435a1d6e7 93 SUPERFAMILY SSF46785 3 92 2.55E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 Pfam PF01416 tRNA pseudouridine synthase 145 246 1.1E-26 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 Pfam PF01416 tRNA pseudouridine synthase 9 105 3.4E-10 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 Gene3D G3DSA:3.30.70.660 108 244 2.1E-44 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 241 1.0E-60 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 SUPERFAMILY SSF55120 2 246 4.46E-78 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 34.612 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 Gene3D G3DSA:3.30.70.580 1 107 7.2E-34 T 12-10-2018 NPD12_3605 ce5177b4448d3e84e53620905e1f1b03 246 PIRSF PIRSF001430 1 246 3.8E-78 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_715 cbec05e881804ffb23c04001b94d3a36 411 Gene3D G3DSA:3.40.350.10 1 170 6.0E-55 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_715 cbec05e881804ffb23c04001b94d3a36 411 Gene3D G3DSA:3.90.230.10 171 411 5.9E-91 T 12-10-2018 NPD12_715 cbec05e881804ffb23c04001b94d3a36 411 Pfam PF00557 Metallopeptidase family M24 177 389 7.5E-60 T 12-10-2018 IPR000994 Peptidase M24 NPD12_715 cbec05e881804ffb23c04001b94d3a36 411 SMART SM01011 1 135 7.8E-36 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 NPD12_715 cbec05e881804ffb23c04001b94d3a36 411 SUPERFAMILY SSF53092 2 171 1.92E-34 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_715 cbec05e881804ffb23c04001b94d3a36 411 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 120 1.9E-27 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 NPD12_715 cbec05e881804ffb23c04001b94d3a36 411 SUPERFAMILY SSF55920 172 410 1.11E-71 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like NPD12_159 1f9ba1ae863b9f4021c599b27d2752bd 295 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 76 294 8.3E-44 T 12-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 NPD12_159 1f9ba1ae863b9f4021c599b27d2752bd 295 Pfam PF02666 Phosphatidylserine decarboxylase 86 292 9.2E-58 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 NPD12_159 1f9ba1ae863b9f4021c599b27d2752bd 295 Hamap MF_00663 Phosphatidylserine decarboxylase proenzyme [psd]. 1 294 43.736 T 12-10-2018 IPR033179 Phosphatidylserine decarboxylase, prokaryotic type 2 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 NPD12_73 722bfd2e598448310495496d676a0238 326 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 324 9.5E-31 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_73 722bfd2e598448310495496d676a0238 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 6.7E-30 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_73 722bfd2e598448310495496d676a0238 326 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 323 1.5E-114 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_73 722bfd2e598448310495496d676a0238 326 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 324 67.67 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_73 722bfd2e598448310495496d676a0238 326 SUPERFAMILY SSF53901 4 324 1.81E-60 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_73 722bfd2e598448310495496d676a0238 326 Gene3D G3DSA:3.40.47.10 2 326 8.0E-125 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Gene3D G3DSA:4.10.780.10 628 668 3.7E-10 T 12-10-2018 IPR037112 Pyruvate-flavodoxin oxidoreductase, EKR domain superfamily NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Gene3D G3DSA:3.40.920.10 414 624 5.0E-91 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 978 1089 2.7E-8 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 SMART SM00890 620 679 1.6E-35 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Gene3D G3DSA:3.40.50.920 258 413 3.9E-59 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 743 754 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Gene3D G3DSA:3.40.50.970 1 257 1.1E-110 T 12-10-2018 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 246 2.0E-80 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 SUPERFAMILY SSF53323 415 668 5.1E-88 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Pfam PF12838 4Fe-4S dicluster domain 688 755 2.1E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Gene3D G3DSA:3.30.70.20 669 782 1.2E-42 T 12-10-2018 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 SUPERFAMILY SSF52922 258 412 1.26E-48 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Pfam PF10371 Domain of unknown function 630 678 3.2E-26 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 SUPERFAMILY SSF52518 784 1191 1.25E-129 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Gene3D G3DSA:3.40.50.970 784 1192 1.2E-172 T 12-10-2018 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 268 373 1.1E-16 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II NPD12_2793 70db791540a1a35a73dceab20719e207 1192 SUPERFAMILY SSF54862 665 829 1.88E-22 T 12-10-2018 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 SUPERFAMILY SSF52518 3 257 3.24E-78 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_2793 70db791540a1a35a73dceab20719e207 1192 PIRSF PIRSF000159 1 1192 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 424 607 1.1E-31 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 NPD12_2793 70db791540a1a35a73dceab20719e207 1192 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 4 1191 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 NPD12_3211 7803ca21ef578c069df02731867ca118 367 SUPERFAMILY SSF53756 32 359 2.45E-16 T 12-10-2018 NPD12_3211 7803ca21ef578c069df02731867ca118 367 Pfam PF13692 Glycosyl transferases group 1 207 310 1.5E-6 T 12-10-2018 NPD12_3211 7803ca21ef578c069df02731867ca118 367 Gene3D G3DSA:3.40.50.2000 183 349 1.1E-20 T 12-10-2018 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 SUPERFAMILY SSF47323 579 831 2.43E-71 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 565 1.7E-212 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Gene3D G3DSA:3.40.50.620 27 528 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 SUPERFAMILY SSF46589 816 880 2.56E-16 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Gene3D G3DSA:1.10.287.380 809 881 1.4E-16 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Gene3D G3DSA:1.10.730.10 7 743 0.0 T 12-10-2018 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 816 881 1.1E-18 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 862 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 SUPERFAMILY SSF50677 196 345 1.7E-63 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Pfam PF08264 Anticodon-binding domain of tRNA 610 757 1.2E-46 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 PRINTS PR00986 Valyl-tRNA synthetase signature 235 252 1.6E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 1.6E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 1.6E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 PRINTS PR00986 Valyl-tRNA synthetase signature 350 363 1.6E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 PRINTS PR00986 Valyl-tRNA synthetase signature 41 52 1.6E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 SUPERFAMILY SSF52374 6 577 2.07E-143 T 12-10-2018 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Gene3D G3DSA:3.90.740.10 180 346 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 NPD12_3276 a596093b8e4a52d44406314bca6cb39b 881 Hamap MF_02004 Valine--tRNA ligase [valS]. 7 881 16.034 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 Gene3D G3DSA:1.10.10.410 414 473 5.3E-24 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 Gene3D G3DSA:1.10.150.380 298 411 2.5E-38 T 12-10-2018 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 471 3.0E-179 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 Pfam PF02934 GatB/GatE catalytic domain 5 287 2.6E-115 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 SUPERFAMILY SSF89095 295 401 4.32E-33 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 39.0 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 Pfam PF02637 GatB domain 326 471 4.8E-52 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 SUPERFAMILY SSF55931 4 294 1.24E-121 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 NPD12_3394 8c1064544191e2fc947d0b3bed3a6c0c 476 SMART SM00845 326 473 3.6E-72 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 NPD12_2771 7d2c98f6d1749c6c2b9ddbc6e9fbb6bf 143 SUPERFAMILY SSF141457 1 141 6.15E-49 T 12-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily NPD12_2771 7d2c98f6d1749c6c2b9ddbc6e9fbb6bf 143 Gene3D G3DSA:2.30.290.10 1 143 3.3E-51 T 12-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily NPD12_2771 7d2c98f6d1749c6c2b9ddbc6e9fbb6bf 143 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 141 27.112 T 12-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 NPD12_2771 7d2c98f6d1749c6c2b9ddbc6e9fbb6bf 143 Pfam PF02623 FliW protein 19 138 7.3E-40 T 12-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 SUPERFAMILY SSF52374 106 442 6.88E-99 T 12-10-2018 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 Gene3D G3DSA:3.30.1360.70 2 103 2.4E-33 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 120 131 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 SMART SM01016 1 82 2.5E-26 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 SUPERFAMILY SSF55190 3 103 4.05E-26 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 151 164 5.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 112 127 5.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 127 143 5.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 295 316 5.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 Gene3D G3DSA:3.40.50.620 104 441 4.7E-124 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 Gene3D G3DSA:1.10.730.10 442 563 7.9E-35 T 12-10-2018 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 Pfam PF05746 DALR anticodon binding domain 448 563 1.5E-31 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 SMART SM00836 448 563 2.8E-42 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 563 4.1E-154 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 81 4.2E-18 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 Pfam PF00750 tRNA synthetases class I (R) 92 434 7.7E-96 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 SUPERFAMILY SSF47323 442 563 1.11E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1266 5444145b8e4b2dec91c0735474d6ea3e 563 Hamap MF_00123 Arginine--tRNA ligase [argS]. 1 563 25.98 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 NPD12_609 a4c132b9725707b110f75e185aa17f08 310 Pfam PF01734 Patatin-like phospholipase 6 198 2.4E-24 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 NPD12_609 a4c132b9725707b110f75e185aa17f08 310 SUPERFAMILY SSF52151 6 300 3.92E-36 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase NPD12_609 a4c132b9725707b110f75e185aa17f08 310 Gene3D G3DSA:3.40.1090.20 2 96 8.3E-17 T 12-10-2018 NPD12_609 a4c132b9725707b110f75e185aa17f08 310 Gene3D G3DSA:3.40.1090.10 112 295 2.8E-18 T 12-10-2018 NPD12_3667 4be9be41ae3353d281694189c8763962 366 Gene3D G3DSA:2.40.50.140 297 359 1.6E-5 T 12-10-2018 NPD12_3667 4be9be41ae3353d281694189c8763962 366 SMART SM00670 169 276 1.2E-14 T 12-10-2018 IPR002716 PIN domain NPD12_3667 4be9be41ae3353d281694189c8763962 366 SUPERFAMILY SSF88723 171 297 6.45E-26 T 12-10-2018 IPR029060 PIN-like domain superfamily NPD12_3667 4be9be41ae3353d281694189c8763962 366 Pfam PF01850 PIN domain 172 279 2.0E-6 T 12-10-2018 IPR002716 PIN domain NPD12_3667 4be9be41ae3353d281694189c8763962 366 Gene3D G3DSA:3.40.50.1010 164 296 5.2E-55 T 12-10-2018 NPD12_3667 4be9be41ae3353d281694189c8763962 366 Pfam PF01938 TRAM domain 300 349 5.7E-6 T 12-10-2018 IPR002792 TRAM domain NPD12_1958 1d668196053b51837f06aab960abbf00 216 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 210 1.1E-77 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 NPD12_1958 1d668196053b51837f06aab960abbf00 216 Pfam PF02224 Cytidylate kinase 5 214 4.2E-78 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 NPD12_1958 1d668196053b51837f06aab960abbf00 216 Gene3D G3DSA:3.40.50.300 2 216 5.1E-84 T 12-10-2018 NPD12_1958 1d668196053b51837f06aab960abbf00 216 SUPERFAMILY SSF52540 5 214 1.37E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1958 1d668196053b51837f06aab960abbf00 216 Hamap MF_00238 Cytidylate kinase [cmk]. 3 216 32.398 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 NPD12_774 b2a6e464b0779198e89ba492b87372d6 407 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.4E-23 T 12-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 NPD12_774 b2a6e464b0779198e89ba492b87372d6 407 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 196 406 5.7E-78 T 12-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 NPD12_774 b2a6e464b0779198e89ba492b87372d6 407 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 406 1.3E-148 T 12-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 NPD12_774 b2a6e464b0779198e89ba492b87372d6 407 Pfam PF07670 Nucleoside recognition 94 190 2.5E-8 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_174 5257ab67bb060fa415c55d2e559ed311 240 SUPERFAMILY SSF51412 82 206 7.96E-14 T 12-10-2018 NPD12_174 5257ab67bb060fa415c55d2e559ed311 240 Gene3D G3DSA:3.20.20.70 82 234 3.3E-13 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3631 99b6ecfe2453d9c60e30c0035fc8c13a 70 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 63 18.15 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3631 99b6ecfe2453d9c60e30c0035fc8c13a 70 TIGRFAM TIGR00012 L29: ribosomal protein uL29 8 63 1.0E-26 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3631 99b6ecfe2453d9c60e30c0035fc8c13a 70 Pfam PF00831 Ribosomal L29 protein 7 62 2.3E-27 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3631 99b6ecfe2453d9c60e30c0035fc8c13a 70 SUPERFAMILY SSF46561 6 65 1.7E-22 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3631 99b6ecfe2453d9c60e30c0035fc8c13a 70 Gene3D G3DSA:1.10.287.310 1 70 4.2E-27 T 12-10-2018 NPD12_3631 99b6ecfe2453d9c60e30c0035fc8c13a 70 ProSitePatterns PS00579 Ribosomal protein L29 signature. 42 56 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 Gene3D G3DSA:2.30.24.10 1 54 6.4E-17 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 Pfam PF03123 CAT RNA binding domain 1 56 4.3E-18 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 SMART SM01061 1 59 1.6E-22 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 Gene3D G3DSA:1.10.1790.10 64 167 3.9E-37 T 12-10-2018 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 SUPERFAMILY SSF50151 1 53 6.02E-14 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 SUPERFAMILY SSF63520 56 166 4.45E-32 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 Gene3D G3DSA:1.10.1790.10 169 276 7.6E-37 T 12-10-2018 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 SUPERFAMILY SSF63520 174 274 1.44E-27 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 Pfam PF00874 PRD domain 76 163 6.9E-24 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_1060 97a56c0e8c87ca4bd573fd0c4a557f69 277 Pfam PF00874 PRD domain 181 273 2.5E-17 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_2338 6df6f315bfae58557b2d43587130c0b3 217 Gene3D G3DSA:3.40.50.360 4 212 1.2E-6 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2338 6df6f315bfae58557b2d43587130c0b3 217 SUPERFAMILY SSF52218 5 136 2.51E-9 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 SMART SM00382 356 548 5.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 Pfam PF00664 ABC transporter transmembrane region 21 280 6.5E-21 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 Gene3D G3DSA:3.40.50.300 324 573 7.7E-87 T 12-10-2018 NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 SUPERFAMILY SSF90123 13 480 2.75E-41 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 SUPERFAMILY SSF52540 326 563 4.65E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 Gene3D G3DSA:1.20.1560.10 3 318 1.9E-33 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1842 97091ca80532fc6824d6c9cb7f1f3773 574 Pfam PF00005 ABC transporter 348 496 1.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_102 863be321b1d226cf0242a5244047d5bd 661 SUPERFAMILY SSF64182 349 647 5.36E-65 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily NPD12_102 863be321b1d226cf0242a5244047d5bd 661 Gene3D G3DSA:3.30.450.20 52 172 4.5E-10 T 12-10-2018 NPD12_102 863be321b1d226cf0242a5244047d5bd 661 Gene3D G3DSA:3.10.310.30 554 658 1.6E-10 T 12-10-2018 NPD12_102 863be321b1d226cf0242a5244047d5bd 661 PIRSF PIRSF026583 1 661 1.3E-218 T 12-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA NPD12_102 863be321b1d226cf0242a5244047d5bd 661 Pfam PF02272 DHHA1 domain 526 651 3.7E-15 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 NPD12_102 863be321b1d226cf0242a5244047d5bd 661 Pfam PF01368 DHH family 349 504 1.2E-20 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_102 863be321b1d226cf0242a5244047d5bd 661 Gene3D G3DSA:3.90.1640.10 332 549 1.3E-53 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 Gene3D G3DSA:3.40.50.1000 420 686 7.1E-79 T 12-10-2018 IPR023214 HAD superfamily NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 SUPERFAMILY SSF56784 437 734 2.22E-55 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 Pfam PF00702 haloacid dehalogenase-like hydrolase 436 647 2.1E-33 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 Gene3D G3DSA:3.30.70.100 4 85 6.9E-11 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 SUPERFAMILY SSF55008 2 72 8.38E-11 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 Pfam PF00403 Heavy-metal-associated domain 10 62 4.6E-12 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 188 738 1.5E-151 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 441 447 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 Gene3D G3DSA:3.40.1110.10 450 561 7.1E-79 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 SUPERFAMILY SSF81665 188 712 9.81E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 Pfam PF00122 E1-E2 ATPase 238 419 8.7E-50 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 208 712 2.2E-71 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 652 4.2E-19 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 287 301 4.2E-19 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 669 4.2E-19 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 577 587 4.2E-19 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 439 453 4.2E-19 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 SUPERFAMILY SSF81653 240 335 3.27E-21 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 188 735 4.8E-168 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 Gene3D G3DSA:2.70.150.20 230 342 3.5E-29 T 12-10-2018 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00941 Cadmium-transporting ATPase signature 7 16 6.1E-7 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00941 Cadmium-transporting ATPase signature 222 242 6.1E-7 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00941 Cadmium-transporting ATPase signature 322 336 6.1E-7 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 NPD12_644 0b49146875f9e737df52fe92ce56b2d3 738 PRINTS PR00941 Cadmium-transporting ATPase signature 303 319 6.1E-7 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 NPD12_731 8266c95f97665d69f035d3bb662a3b0b 231 Pfam PF00005 ABC transporter 20 155 1.9E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_731 8266c95f97665d69f035d3bb662a3b0b 231 SUPERFAMILY SSF52540 4 215 9.59E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_731 8266c95f97665d69f035d3bb662a3b0b 231 SMART SM00382 29 204 2.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_731 8266c95f97665d69f035d3bb662a3b0b 231 Gene3D G3DSA:3.40.50.300 1 230 9.5E-48 T 12-10-2018 NPD12_836 473c79112f6dff1f81e04e6c9b8e6381 410 SMART SM00849 34 223 4.6E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_836 473c79112f6dff1f81e04e6c9b8e6381 410 Pfam PF00258 Flavodoxin 253 364 2.3E-10 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 NPD12_836 473c79112f6dff1f81e04e6c9b8e6381 410 SUPERFAMILY SSF56281 10 283 5.63E-45 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_836 473c79112f6dff1f81e04e6c9b8e6381 410 Gene3D G3DSA:3.40.50.360 250 404 2.8E-33 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_836 473c79112f6dff1f81e04e6c9b8e6381 410 PIRSF PIRSF005243 1 408 1.8E-132 T 12-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 NPD12_836 473c79112f6dff1f81e04e6c9b8e6381 410 SUPERFAMILY SSF52218 248 370 5.0E-31 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_836 473c79112f6dff1f81e04e6c9b8e6381 410 Gene3D G3DSA:3.60.15.10 1 243 6.8E-84 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2064 b235930efd2222a51fe219eb152e536f 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 59.385 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 NPD12_2064 b235930efd2222a51fe219eb152e536f 147 Gene3D G3DSA:3.40.50.9100 1 146 3.2E-60 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 NPD12_2064 b235930efd2222a51fe219eb152e536f 147 Pfam PF01220 Dehydroquinase class II 3 139 1.3E-57 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 NPD12_2064 b235930efd2222a51fe219eb152e536f 147 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 3.0E-59 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 NPD12_2064 b235930efd2222a51fe219eb152e536f 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 140 3.0E-45 T 12-10-2018 NPD12_2064 b235930efd2222a51fe219eb152e536f 147 PIRSF PIRSF001399 1 146 4.8E-64 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 NPD12_2064 b235930efd2222a51fe219eb152e536f 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 NPD12_2064 b235930efd2222a51fe219eb152e536f 147 SUPERFAMILY SSF52304 3 143 2.75E-57 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 NPD12_3408 58947a58f13e69c9eab0ac947323c31f 56 Pfam PF13451 Probable zinc-ribbon domain 3 49 7.6E-26 T 12-10-2018 IPR025306 Probable zinc-binding domain NPD12_893 cd40da0eec98cf2800cafe9fdb51bf97 135 Gene3D G3DSA:3.10.180.10 1 134 2.3E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_893 cd40da0eec98cf2800cafe9fdb51bf97 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 97 5.3E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain NPD12_893 cd40da0eec98cf2800cafe9fdb51bf97 135 SUPERFAMILY SSF54593 3 130 5.24E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 298 304 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 Gene3D G3DSA:3.30.2130.30 7 250 8.3E-120 T 12-10-2018 NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 12-10-2018 IPR000241 Putative RNA methylase domain NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 SUPERFAMILY SSF53335 140 370 1.2E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 Pfam PF01170 Putative RNA methylase family UPF0020 162 366 2.4E-56 T 12-10-2018 IPR000241 Putative RNA methylase domain NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 SMART SM00981 57 154 8.2E-7 T 12-10-2018 IPR004114 THUMP domain GO:0003723 NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 Gene3D G3DSA:3.40.50.150 169 363 8.3E-120 T 12-10-2018 NPD12_1730 cfb5abfe1380fdf13ed482bf766819aa 380 Pfam PF02926 THUMP domain 14 153 3.4E-9 T 12-10-2018 IPR004114 THUMP domain GO:0003723 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 Pfam PF03413 Peptidase propeptide and YPEB domain 148 212 1.7E-6 T 12-10-2018 IPR025711 PepSY domain NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 Gene3D G3DSA:3.10.170.10 254 415 2.7E-43 T 12-10-2018 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 Gene3D G3DSA:1.10.390.10 416 572 1.2E-49 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 SUPERFAMILY SSF55486 253 572 2.56E-80 T 12-10-2018 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 414 572 4.1E-52 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 8.6E-9 T 12-10-2018 IPR011096 FTP domain NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 256 411 1.8E-46 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 423 434 6.9E-19 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 490 506 6.9E-19 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 364 384 6.9E-19 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1696 989bdab2946e9cb5f77e07c2dcd2e71f 580 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 402 418 6.9E-19 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_2872 9ce294c0bf44ab5c29f7651be00c57dd 464 Pfam PF01554 MatE 26 187 5.2E-29 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2872 9ce294c0bf44ab5c29f7651be00c57dd 464 Pfam PF01554 MatE 248 409 1.2E-24 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2872 9ce294c0bf44ab5c29f7651be00c57dd 464 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 416 1.1E-69 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2872 9ce294c0bf44ab5c29f7651be00c57dd 464 PIRSF PIRSF006603 1 458 3.2E-104 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 Gene3D G3DSA:2.40.50.140 1 64 3.9E-29 T 12-10-2018 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 PRINTS PR00050 Cold shock protein signature 3 18 9.9E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 PRINTS PR00050 Cold shock protein signature 23 32 9.9E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 PRINTS PR00050 Cold shock protein signature 38 56 9.9E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 12-10-2018 IPR019844 Cold-shock conserved site NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 PIRSF PIRSF002599 1 65 6.4E-23 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 SMART SM00357 2 65 4.9E-30 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 63 7.3E-30 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_448 4db2e9e95d2c261a0d78972be34a53fd 65 SUPERFAMILY SSF50249 2 64 1.91E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2878 3b24f86213e9723c5ab4da4cce990b11 124 Gene3D G3DSA:3.40.35.10 1 118 3.4E-26 T 12-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 NPD12_2878 3b24f86213e9723c5ab4da4cce990b11 124 SUPERFAMILY SSF52728 2 116 1.44E-28 T 12-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 NPD12_2878 3b24f86213e9723c5ab4da4cce990b11 124 Pfam PF03830 PTS system sorbose subfamily IIB component 2 106 1.7E-25 T 12-10-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 NPD12_1722 e3f34cc16720b8950da9d79ce92ffd4b 266 SUPERFAMILY SSF51569 5 265 6.04E-97 T 12-10-2018 NPD12_1722 e3f34cc16720b8950da9d79ce92ffd4b 266 Pfam PF00793 DAHP synthetase I family 16 265 1.0E-75 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 NPD12_1722 e3f34cc16720b8950da9d79ce92ffd4b 266 Gene3D G3DSA:3.20.20.70 2 263 5.7E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1722 e3f34cc16720b8950da9d79ce92ffd4b 266 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 9 261 1.3E-112 T 12-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 NPD12_572 8ddb423bb701a3d99db4422207ba1f57 308 SUPERFAMILY SSF158430 181 306 5.49E-39 T 12-10-2018 NPD12_572 8ddb423bb701a3d99db4422207ba1f57 308 SUPERFAMILY SSF158430 8 188 1.7E-41 T 12-10-2018 NPD12_572 8ddb423bb701a3d99db4422207ba1f57 308 Pfam PF11155 Domain of unknown function (DUF2935) 9 176 3.6E-45 T 12-10-2018 IPR021328 Protein of unknown function DUF2935 NPD12_572 8ddb423bb701a3d99db4422207ba1f57 308 Pfam PF11155 Domain of unknown function (DUF2935) 190 302 9.1E-36 T 12-10-2018 IPR021328 Protein of unknown function DUF2935 NPD12_572 8ddb423bb701a3d99db4422207ba1f57 308 Gene3D G3DSA:1.20.1260.120 1 78 5.9E-15 T 12-10-2018 NPD12_572 8ddb423bb701a3d99db4422207ba1f57 308 Gene3D G3DSA:1.20.1260.120 102 308 6.0E-65 T 12-10-2018 NPD12_2116 a4936233d5798bf81c9973c867fc903e 223 Gene3D G3DSA:3.40.50.300 1 222 3.0E-60 T 12-10-2018 NPD12_2116 a4936233d5798bf81c9973c867fc903e 223 SMART SM00382 33 219 1.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2116 a4936233d5798bf81c9973c867fc903e 223 SUPERFAMILY SSF52540 3 219 3.36E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2116 a4936233d5798bf81c9973c867fc903e 223 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2116 a4936233d5798bf81c9973c867fc903e 223 Pfam PF00005 ABC transporter 24 170 1.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1297 8eae7e28a06bc94f362095f97fdab8b9 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 419 1.4E-66 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_1297 8eae7e28a06bc94f362095f97fdab8b9 455 PIRSF PIRSF006603 1 453 1.3E-96 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_1297 8eae7e28a06bc94f362095f97fdab8b9 455 Pfam PF01554 MatE 22 185 3.1E-26 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_1297 8eae7e28a06bc94f362095f97fdab8b9 455 Pfam PF01554 MatE 252 407 1.1E-21 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_1780 456b375b309a44b1e06e55a08207d41e 467 Pfam PF00854 POT family 238 420 1.2E-36 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_1780 456b375b309a44b1e06e55a08207d41e 467 Pfam PF00854 POT family 85 208 1.6E-19 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_1780 456b375b309a44b1e06e55a08207d41e 467 Gene3D G3DSA:1.20.1250.20 228 465 5.6E-55 T 12-10-2018 NPD12_1780 456b375b309a44b1e06e55a08207d41e 467 Gene3D G3DSA:1.20.1250.20 1 226 3.9E-57 T 12-10-2018 NPD12_1780 456b375b309a44b1e06e55a08207d41e 467 SUPERFAMILY SSF103473 7 450 1.57E-36 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_1780 456b375b309a44b1e06e55a08207d41e 467 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 10 231 1.2E-41 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 NPD12_1780 456b375b309a44b1e06e55a08207d41e 467 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 232 452 9.6E-40 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 NPD12_3620 76092296c5b170ca4d630141d0e61921 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 7.6E-41 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P NPD12_3620 76092296c5b170ca4d630141d0e61921 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.849 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 NPD12_3620 76092296c5b170ca4d630141d0e61921 146 SUPERFAMILY SSF52080 4 144 2.09E-51 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily NPD12_3620 76092296c5b170ca4d630141d0e61921 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 2.5E-56 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3620 76092296c5b170ca4d630141d0e61921 146 Gene3D G3DSA:3.100.10.10 66 146 1.2E-27 T 12-10-2018 NPD12_3620 76092296c5b170ca4d630141d0e61921 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_680 8a8ed35bedd228d9e67c031b708d7f87 206 Gene3D G3DSA:1.10.10.10 5 126 2.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_680 8a8ed35bedd228d9e67c031b708d7f87 206 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 2.9E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_680 8a8ed35bedd228d9e67c031b708d7f87 206 Pfam PF02080 TrkA-C domain 133 203 1.4E-16 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 NPD12_680 8a8ed35bedd228d9e67c031b708d7f87 206 SMART SM00345 12 71 3.4E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_680 8a8ed35bedd228d9e67c031b708d7f87 206 SUPERFAMILY SSF46785 4 83 2.06E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_680 8a8ed35bedd228d9e67c031b708d7f87 206 SUPERFAMILY SSF116726 123 203 4.05E-18 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_680 8a8ed35bedd228d9e67c031b708d7f87 206 Gene3D G3DSA:3.30.70.1450 132 204 1.5E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1311 ab29bda45f4e0ab57c5434fbf363364e 67 Pfam PF00403 Heavy-metal-associated domain 6 65 1.6E-7 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_1311 ab29bda45f4e0ab57c5434fbf363364e 67 Gene3D G3DSA:3.30.70.100 1 66 2.6E-11 T 12-10-2018 NPD12_1311 ab29bda45f4e0ab57c5434fbf363364e 67 SUPERFAMILY SSF55008 3 66 2.62E-11 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_2947 de125cb9655d9650aee67e584bbcb97a 322 Gene3D G3DSA:1.10.3470.10 3 321 3.7E-94 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_2947 de125cb9655d9650aee67e584bbcb97a 322 Pfam PF01032 FecCD transport family 14 315 2.2E-85 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_2947 de125cb9655d9650aee67e584bbcb97a 322 SUPERFAMILY SSF81345 7 315 3.66E-75 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_2326 5775daf463d249b7038cbef948559cb2 329 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 312 8.3E-117 T 12-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal NPD12_2326 5775daf463d249b7038cbef948559cb2 329 Gene3D G3DSA:3.60.60.10 2 329 3.0E-120 T 12-10-2018 NPD12_2326 5775daf463d249b7038cbef948559cb2 329 SUPERFAMILY SSF56235 2 327 5.17E-111 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_2003 f717edf8eb77fec5d6707092d1acf259 395 Gene3D G3DSA:1.20.1530.20 2 385 4.1E-31 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_2003 f717edf8eb77fec5d6707092d1acf259 395 Pfam PF00999 Sodium/hydrogen exchanger family 7 378 9.4E-41 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 NPD12_1454 f239139b7093f3d674bc1fd2d6b2fd8c 203 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 6 197 1.3E-59 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 NPD12_1454 f239139b7093f3d674bc1fd2d6b2fd8c 203 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 4 201 1.7E-57 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 NPD12_1454 f239139b7093f3d674bc1fd2d6b2fd8c 203 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 5 201 33.138 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 NPD12_1454 f239139b7093f3d674bc1fd2d6b2fd8c 203 Gene3D G3DSA:3.10.300.10 1 203 1.4E-71 T 12-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 NPD12_1454 f239139b7093f3d674bc1fd2d6b2fd8c 203 SUPERFAMILY SSF50486 2 202 4.16E-66 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 NPD12_1533 2ee1fcbf7b183cd50641dc0079979265 98 SMART SM00679 21 52 0.0039 T 12-10-2018 IPR006603 PQ-loop repeat NPD12_1533 2ee1fcbf7b183cd50641dc0079979265 98 Pfam PF04193 PQ loop repeat 8 65 7.8E-8 T 12-10-2018 IPR006603 PQ-loop repeat NPD12_1533 2ee1fcbf7b183cd50641dc0079979265 98 Gene3D G3DSA:1.20.1280.290 5 94 8.5E-11 T 12-10-2018 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 Pfam PF01235 Sodium:alanine symporter family 60 454 4.0E-167 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PIRSF PIRSF006060 289 457 4.8 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PIRSF PIRSF006060 52 269 1.0E-11 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PIRSF PIRSF006060 1 49 37.0 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 442 3.4E-161 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PRINTS PR00175 Sodium/alanine symporter signature 97 119 1.1E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PRINTS PR00175 Sodium/alanine symporter signature 306 324 1.1E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PRINTS PR00175 Sodium/alanine symporter signature 411 431 1.1E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PRINTS PR00175 Sodium/alanine symporter signature 187 205 1.1E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PRINTS PR00175 Sodium/alanine symporter signature 215 234 1.1E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 PRINTS PR00175 Sodium/alanine symporter signature 351 373 1.1E-61 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1436 b9de1d9df515aa4891524dfd3577a723 478 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 97 112 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2524 bbcd6aebfd6c858e007c423cd722a319 258 TIGRFAM TIGR04482 D_pro_red_PrdD: proline reductase cluster protein PrdD 8 258 2.4E-118 T 12-10-2018 IPR031000 Proline reductase cluster protein PrdD NPD12_2524 bbcd6aebfd6c858e007c423cd722a319 258 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 9 252 2.6E-7 T 12-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 3.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 3.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 Gene3D G3DSA:2.60.120.10 7 104 3.0E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 Pfam PF02311 AraC-like ligand binding domain 32 98 2.0E-7 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 SUPERFAMILY SSF51215 16 161 8.37E-21 T 12-10-2018 IPR037923 Transcription regulator HTH-like NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 Gene3D G3DSA:1.10.10.60 181 292 1.6E-22 T 12-10-2018 NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 Pfam PF12833 Helix-turn-helix domain 212 290 2.0E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 SUPERFAMILY SSF46689 243 290 3.32E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1384 6ead9276743e66cc9369a62047d3af61 296 SMART SM00342 206 289 1.3E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_3037 754e94413f665899bca33b712898d7d1 225 Pfam PF01476 LysM domain 177 225 1.0E-11 T 12-10-2018 IPR018392 LysM domain NPD12_3037 754e94413f665899bca33b712898d7d1 225 Gene3D G3DSA:3.10.350.10 175 223 1.1E-15 T 12-10-2018 IPR036779 LysM domain superfamily NPD12_3037 754e94413f665899bca33b712898d7d1 225 SUPERFAMILY SSF54106 174 225 1.09E-8 T 12-10-2018 NPD12_3037 754e94413f665899bca33b712898d7d1 225 SMART SM00257 176 225 3.3E-7 T 12-10-2018 IPR018392 LysM domain NPD12_374 397761e41b9069ff5863214131d112e9 335 SUPERFAMILY SSF102114 81 248 8.89E-5 T 12-10-2018 NPD12_374 397761e41b9069ff5863214131d112e9 335 Gene3D G3DSA:3.80.30.30 112 335 1.0E-73 T 12-10-2018 NPD12_374 397761e41b9069ff5863214131d112e9 335 Gene3D G3DSA:3.40.50.12110 1 111 3.4E-40 T 12-10-2018 NPD12_374 397761e41b9069ff5863214131d112e9 335 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 2 335 2.2E-163 T 12-10-2018 IPR023897 Spore photoproduct lyase GO:0003913 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 341 364 3.9E-8 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 323 332 3.9E-8 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 67 86 3.9E-8 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 Gene3D G3DSA:3.40.50.1370 6 391 5.8E-207 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 Gene3D G3DSA:3.40.50.1370 168 363 5.8E-207 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 PRINTS PR00101 Aspartate carbamoyltransferase signature 95 104 2.6E-6 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 PRINTS PR00101 Aspartate carbamoyltransferase signature 164 181 2.6E-6 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 PRINTS PR00101 Aspartate carbamoyltransferase signature 57 79 2.6E-6 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 24 176 3.1E-27 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 TIGRFAM TIGR03316 ygeW: knotted carbamoyltransferase YgeW 4 394 8.4E-240 T 12-10-2018 IPR017702 Putative carbamoyltransferase YgeW NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 SUPERFAMILY SSF53671 18 374 1.96E-58 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_2937 6fd2cbe855ce4335c6efa3efd5c7188d 398 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 187 374 2.8E-46 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 NPD12_160 ed50775849b4c11ce4b411c6b66240e6 532 SUPERFAMILY SSF56112 75 310 5.3E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_160 ed50775849b4c11ce4b411c6b66240e6 532 Pfam PF03109 ABC1 family 93 208 6.5E-28 T 12-10-2018 IPR004147 UbiB domain NPD12_160 ed50775849b4c11ce4b411c6b66240e6 532 Gene3D G3DSA:1.10.510.10 234 316 1.3E-5 T 12-10-2018 NPD12_978 2d22ed35b7b98e7715d09cb8247710f8 62 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 57 14.53 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 NPD12_978 2d22ed35b7b98e7715d09cb8247710f8 62 Pfam PF08141 Small acid-soluble spore protein H family 1 54 1.5E-16 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 NPD12_978 2d22ed35b7b98e7715d09cb8247710f8 62 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 56 7.0E-24 T 12-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 SUPERFAMILY SSF64307 2 70 3.4E-13 T 12-10-2018 IPR036868 TusA-like domain superfamily NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 Pfam PF02635 DsrE/DsrF-like family 132 192 3.0E-5 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 Gene3D G3DSA:3.40.1260.10 82 191 1.9E-5 T 12-10-2018 IPR027396 DsrEFH-like NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 Pfam PF01206 Sulfurtransferase TusA 4 70 1.1E-15 T 12-10-2018 IPR001455 TusA-like domain NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 Gene3D G3DSA:3.30.110.40 3 81 4.9E-22 T 12-10-2018 IPR036868 TusA-like domain superfamily NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 SUPERFAMILY SSF75169 95 193 1.22E-14 T 12-10-2018 IPR027396 DsrEFH-like NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 TIGRFAM TIGR03527 selenium_YedF: selenium metabolism protein YedF 5 193 2.6E-73 T 12-10-2018 IPR019870 Selenium metabolism protein YedF NPD12_2620 bacbc7540b67ea2f199d0bd92dd28c34 194 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 5 29 - T 12-10-2018 IPR001455 TusA-like domain NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 SMART SM00387 342 448 8.6E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 Gene3D G3DSA:3.30.565.10 291 444 6.5E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 SMART SM00388 229 296 1.1E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 293 8.0E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 SUPERFAMILY SSF55874 300 435 5.11E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 435 6.3E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 SUPERFAMILY SSF47384 212 294 3.92E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 212 226 9.6E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 9.6E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 9.6E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_3493 97a9445e3f7dc48faa2af1c82cf05ea5 448 Gene3D G3DSA:1.10.287.130 178 290 3.0E-21 T 12-10-2018 NPD12_2433 243eb8c9b463a03c8ea4df34cc4b2005 112 Pfam PF10127 Predicted nucleotidyltransferase 6 104 2.6E-18 T 12-10-2018 IPR018775 Nucleotidyltransferase, predicted NPD12_2433 243eb8c9b463a03c8ea4df34cc4b2005 112 SUPERFAMILY SSF81301 6 71 2.9E-5 T 12-10-2018 NPD12_3285 800d56d0da6a54924027b958edbba55c 391 SMART SM00460 304 366 2.3E-19 T 12-10-2018 IPR002931 Transglutaminase-like NPD12_3285 800d56d0da6a54924027b958edbba55c 391 Pfam PF01841 Transglutaminase-like superfamily 253 364 1.2E-21 T 12-10-2018 IPR002931 Transglutaminase-like NPD12_3285 800d56d0da6a54924027b958edbba55c 391 Gene3D G3DSA:3.10.620.30 203 381 1.3E-29 T 12-10-2018 NPD12_3285 800d56d0da6a54924027b958edbba55c 391 SUPERFAMILY SSF54001 171 366 4.05E-32 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 105 4.7E-36 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 9.3E-141 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 Gene3D G3DSA:3.30.360.10 154 318 8.2E-155 T 12-10-2018 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 3.5E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 3.5E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 3.5E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 3.5E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 3.5E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 PIRSF PIRSF000149 1 338 4.0E-139 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 SUPERFAMILY SSF55347 155 317 1.37E-73 T 12-10-2018 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 SMART SM00846 3 155 9.3E-92 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 Gene3D G3DSA:3.40.50.720 4 332 8.2E-155 T 12-10-2018 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 1.7E-70 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1289 53f9db9a28f598d750d50645fc2c0d15 338 SUPERFAMILY SSF51735 3 171 3.82E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 Gene3D G3DSA:3.40.1010.10 1 117 1.3E-12 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 SUPERFAMILY SSF101386 227 328 8.34E-25 T 12-10-2018 NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 205 3.5E-28 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 TIGRFAM TIGR00444 mazG: MazG family protein 235 479 1.5E-93 T 12-10-2018 IPR011551 NTP pyrophosphohydrolase MazG NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 SUPERFAMILY SSF101386 360 453 2.06E-25 T 12-10-2018 NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 Gene3D G3DSA:1.10.287.1080 226 348 9.4E-42 T 12-10-2018 NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 SUPERFAMILY SSF53790 1 253 3.34E-33 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 387 448 2.0E-8 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 251 324 5.2E-29 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 Gene3D G3DSA:1.10.287.1080 355 481 5.6E-43 T 12-10-2018 NPD12_5 4ae2314fe2871703725296b7f2f350e0 481 PIRSF PIRSF002845 1 481 8.6E-224 T 12-10-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted NPD12_1082 444429cb60d5c6d50a0178491bf9da7a 125 SUPERFAMILY SSF55729 17 110 2.61E-13 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1082 444429cb60d5c6d50a0178491bf9da7a 125 Pfam PF13302 Acetyltransferase (GNAT) domain 41 98 7.1E-6 T 12-10-2018 IPR000182 GNAT domain NPD12_1082 444429cb60d5c6d50a0178491bf9da7a 125 Gene3D G3DSA:3.40.630.30 6 104 4.3E-19 T 12-10-2018 NPD12_3500 074ecb4ab0eaf5e8116b74aa60e0e567 297 Gene3D G3DSA:3.30.420.40 110 281 2.7E-63 T 12-10-2018 NPD12_3500 074ecb4ab0eaf5e8116b74aa60e0e567 297 SUPERFAMILY SSF53067 111 296 3.56E-44 T 12-10-2018 NPD12_3500 074ecb4ab0eaf5e8116b74aa60e0e567 297 SUPERFAMILY SSF53067 1 106 5.46E-17 T 12-10-2018 NPD12_3500 074ecb4ab0eaf5e8116b74aa60e0e567 297 Gene3D G3DSA:3.30.420.40 4 292 2.7E-63 T 12-10-2018 NPD12_3500 074ecb4ab0eaf5e8116b74aa60e0e567 297 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 289 4.9E-25 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 Gene3D G3DSA:3.40.50.620 15 615 1.2E-248 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 SUPERFAMILY SSF47323 645 881 7.29E-57 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 SUPERFAMILY SSF47323 952 1033 4.05E-6 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 221 244 6.7E-29 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 509 522 6.7E-29 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 41 52 6.7E-29 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 6.7E-29 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 558 6.7E-29 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 Pfam PF08264 Anticodon-binding domain of tRNA 676 827 4.8E-37 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 Gene3D G3DSA:1.10.730.10 631 819 5.7E-61 T 12-10-2018 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 7 833 1.0E-292 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 Gene3D G3DSA:3.90.740.10 197 390 1.2E-248 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 SUPERFAMILY SSF52374 10 638 6.97E-135 T 12-10-2018 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1038 14.187 T 12-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 619 9.7E-189 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_254 b798dc44934db86c57fc5d160bcff413 1038 SUPERFAMILY SSF50677 199 386 3.53E-51 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 NPD12_3639 bed3a9722fdf0b8d9ee28df9a62963f6 209 Gene3D G3DSA:2.40.50.620 32 97 6.5E-19 T 12-10-2018 NPD12_3639 bed3a9722fdf0b8d9ee28df9a62963f6 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 204 4.6E-87 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3639 bed3a9722fdf0b8d9ee28df9a62963f6 209 SUPERFAMILY SSF50447 2 208 5.03E-82 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_3639 bed3a9722fdf0b8d9ee28df9a62963f6 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site NPD12_3639 bed3a9722fdf0b8d9ee28df9a62963f6 209 Gene3D G3DSA:2.40.30.10 132 209 2.5E-14 T 12-10-2018 NPD12_3639 bed3a9722fdf0b8d9ee28df9a62963f6 209 Pfam PF00297 Ribosomal protein L3 95 180 1.4E-17 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3639 bed3a9722fdf0b8d9ee28df9a62963f6 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 207 38.706 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2504 f72527e4dbc0517de67145be9db81ab1 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 74 9.8E-35 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 NPD12_2504 f72527e4dbc0517de67145be9db81ab1 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 30 45 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site NPD12_2504 f72527e4dbc0517de67145be9db81ab1 77 Pfam PF00550 Phosphopantetheine attachment site 4 71 3.4E-17 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain NPD12_2504 f72527e4dbc0517de67145be9db81ab1 77 Hamap MF_01217 Acyl carrier protein [acpP]. 1 75 23.244 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 NPD12_2504 f72527e4dbc0517de67145be9db81ab1 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 74 7.0E-11 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 NPD12_2504 f72527e4dbc0517de67145be9db81ab1 77 Gene3D G3DSA:1.10.1200.10 1 77 2.5E-30 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2504 f72527e4dbc0517de67145be9db81ab1 77 SUPERFAMILY SSF47336 2 74 5.5E-24 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 Pfam PF00375 Sodium:dicarboxylate symporter family 13 403 3.8E-95 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 SUPERFAMILY SSF118215 11 403 3.53E-83 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 4.5E-18 T 12-10-2018 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 4.5E-18 T 12-10-2018 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 4.5E-18 T 12-10-2018 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 4.5E-18 T 12-10-2018 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 4.5E-18 T 12-10-2018 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 4.5E-18 T 12-10-2018 NPD12_740 18d7881ab8ab006c0ca81b2c66aa6cc9 417 Gene3D G3DSA:1.10.3860.10 1 408 1.5E-81 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_3332 29a72d0c4991a3581f6402c91ba1f4dc 411 Pfam PF13416 Bacterial extracellular solute-binding protein 52 349 1.2E-19 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein NPD12_3332 29a72d0c4991a3581f6402c91ba1f4dc 411 Gene3D G3DSA:3.40.190.10 20 411 1.5E-33 T 12-10-2018 NPD12_3332 29a72d0c4991a3581f6402c91ba1f4dc 411 SUPERFAMILY SSF53850 22 407 3.21E-34 T 12-10-2018 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 33 51 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 SMART SM00418 10 88 5.0E-28 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 Pfam PF01022 Bacterial regulatory protein, arsR family 17 63 6.8E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 4.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 4.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 4.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 4.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 SUPERFAMILY SSF46785 4 88 2.93E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_937 a28a77f437117f48357a3474ccfe7ae1 107 Gene3D G3DSA:1.10.10.10 2 96 6.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 Gene3D G3DSA:3.30.300.10 391 510 3.7E-54 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 3.6E-6 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 3.6E-6 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 3.6E-6 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 Pfam PF00958 GMP synthase C terminal domain 418 509 8.2E-45 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 Pfam PF02540 NAD synthase 205 276 3.4E-6 T 12-10-2018 IPR022310 NAD/GMP synthase NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 Gene3D G3DSA:3.40.50.880 3 197 1.3E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 3.9E-5 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 6 20 3.9E-5 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 3.9E-5 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 SUPERFAMILY SSF52402 181 432 1.57E-57 T 12-10-2018 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 SUPERFAMILY SSF52317 5 198 2.62E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 201 510 3.6E-159 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 510 56.092 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 Pfam PF00117 Glutamine amidotransferase class-I 8 188 1.1E-41 T 12-10-2018 IPR017926 Glutamine amidotransferase NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 Gene3D G3DSA:3.40.50.620 198 390 1.8E-79 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3423 f969d46ddc4b5726cdb464adc65902ca 510 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 192 2.0E-80 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 PIRSF PIRSF000726 59 400 2.3E-106 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 PIRSF PIRSF000726 1 62 5.7E-21 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 Gene3D G3DSA:3.30.70.260 256 400 1.6E-37 T 12-10-2018 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 Gene3D G3DSA:3.40.1160.10 1 255 3.1E-83 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 Pfam PF13840 ACT domain 333 392 5.1E-7 T 12-10-2018 IPR027795 CASTOR, ACT domain NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 Gene3D G3DSA:3.30.70.260 261 335 1.6E-37 T 12-10-2018 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 Pfam PF00696 Amino acid kinase family 3 228 7.4E-48 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 SUPERFAMILY SSF53633 4 241 4.06E-66 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 60 398 3.4E-101 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 SUPERFAMILY SSF55021 329 399 6.15E-16 T 12-10-2018 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 SUPERFAMILY SSF55021 252 326 1.51E-13 T 12-10-2018 NPD12_3478 84650c9e30d0c69e7a24aab1c1ff600b 400 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_912 53cfade111da67de5acb2c4e99ef30c5 302 SUPERFAMILY SSF53686 1 299 2.36E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme NPD12_912 53cfade111da67de5acb2c4e99ef30c5 302 Gene3D G3DSA:3.40.50.1100 9 298 7.6E-117 T 12-10-2018 NPD12_912 53cfade111da67de5acb2c4e99ef30c5 302 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 NPD12_912 53cfade111da67de5acb2c4e99ef30c5 302 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 302 9.5E-108 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 NPD12_912 53cfade111da67de5acb2c4e99ef30c5 302 Gene3D G3DSA:3.40.50.1100 45 146 7.6E-117 T 12-10-2018 NPD12_912 53cfade111da67de5acb2c4e99ef30c5 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 291 1.0E-69 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme NPD12_912 53cfade111da67de5acb2c4e99ef30c5 302 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 302 2.6E-109 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 SUPERFAMILY SSF53067 303 556 5.04E-38 T 12-10-2018 NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 306 554 1.2E-57 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 Gene3D G3DSA:3.30.420.40 306 554 3.5E-81 T 12-10-2018 NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 Gene3D G3DSA:3.30.420.40 397 537 3.5E-81 T 12-10-2018 NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 304 553 6.1E-74 T 12-10-2018 IPR008275 CoA enzyme activase NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 Gene3D G3DSA:3.40.50.11890 1 120 1.1E-16 T 12-10-2018 NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 6 134 2.2E-11 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 146 283 1.4E-17 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_2322 40ab7f748d06d90b3470bb658d47b80a 564 Gene3D G3DSA:3.40.50.11900 148 296 1.2E-26 T 12-10-2018 NPD12_2972 a72bd58862c8f5bc1bce1def390aa71d 225 SUPERFAMILY SSF46785 152 223 1.57E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2972 a72bd58862c8f5bc1bce1def390aa71d 225 Pfam PF13545 Crp-like helix-turn-helix domain 154 223 3.3E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_2972 a72bd58862c8f5bc1bce1def390aa71d 225 Pfam PF00027 Cyclic nucleotide-binding domain 34 120 8.9E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_2972 a72bd58862c8f5bc1bce1def390aa71d 225 SUPERFAMILY SSF51206 1 147 2.09E-33 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like NPD12_2972 a72bd58862c8f5bc1bce1def390aa71d 225 SMART SM00100 13 148 6.3E-8 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_2972 a72bd58862c8f5bc1bce1def390aa71d 225 Gene3D G3DSA:2.60.120.1460 2 220 4.2E-68 T 12-10-2018 NPD12_2167 5d95d9b562da214d4c29a0267244d2ea 182 Pfam PF00990 Diguanylate cyclase, GGDEF domain 31 180 9.4E-36 T 12-10-2018 IPR000160 GGDEF domain NPD12_2167 5d95d9b562da214d4c29a0267244d2ea 182 SMART SM00267 18 182 3.8E-30 T 12-10-2018 IPR000160 GGDEF domain NPD12_2167 5d95d9b562da214d4c29a0267244d2ea 182 SUPERFAMILY SSF55073 35 179 6.54E-35 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_2167 5d95d9b562da214d4c29a0267244d2ea 182 Gene3D G3DSA:3.30.70.270 15 182 4.5E-40 T 12-10-2018 NPD12_2167 5d95d9b562da214d4c29a0267244d2ea 182 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 31 179 2.0E-37 T 12-10-2018 IPR000160 GGDEF domain NPD12_2260 89364b9662bdd6af04271345b50f7f13 437 PIRSF PIRSF006603 1 435 3.8E-63 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2260 89364b9662bdd6af04271345b50f7f13 437 TIGRFAM TIGR00797 matE: MATE efflux family protein 15 408 3.1E-47 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2260 89364b9662bdd6af04271345b50f7f13 437 Pfam PF01554 MatE 236 394 3.2E-17 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2260 89364b9662bdd6af04271345b50f7f13 437 Pfam PF01554 MatE 15 174 3.6E-20 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 PRINTS PR00415 Aconitase family signature 110 123 2.6E-23 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 PRINTS PR00415 Aconitase family signature 186 199 2.6E-23 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 PRINTS PR00415 Aconitase family signature 349 362 2.6E-23 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 PRINTS PR00415 Aconitase family signature 90 98 2.6E-23 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 PRINTS PR00415 Aconitase family signature 200 213 2.6E-23 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 PRINTS PR00415 Aconitase family signature 124 139 2.6E-23 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 4 638 7.0E-280 T 12-10-2018 IPR006250 Aconitase, putative NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 Gene3D G3DSA:3.30.499.10 270 435 6.8E-52 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 Gene3D G3DSA:3.20.19.10 461 641 2.0E-47 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 ProSitePatterns PS01244 Aconitase family signature 2. 349 362 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 SUPERFAMILY SSF53732 2 417 3.92E-151 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 Pfam PF00694 Aconitase C-terminal domain 514 575 6.5E-25 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 Gene3D G3DSA:3.30.499.20 4 267 6.2E-89 T 12-10-2018 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 SUPERFAMILY SSF52016 439 638 1.28E-55 T 12-10-2018 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 NPD12_588 35b3558a8b63bed7083e3df6e9997879 641 Pfam PF00330 Aconitase family (aconitate hydratase) 7 407 7.3E-110 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 NPD12_2945 1a1da2e0c7142daede4f082fee25e120 269 Pfam PF13478 XdhC Rossmann domain 107 249 6.6E-39 T 12-10-2018 IPR027051 XdhC Rossmann domain NPD12_2945 1a1da2e0c7142daede4f082fee25e120 269 Pfam PF02625 XdhC and CoxI family 14 78 1.3E-18 T 12-10-2018 IPR003777 XdhC- CoxI NPD12_2945 1a1da2e0c7142daede4f082fee25e120 269 Gene3D G3DSA:3.40.50.720 106 268 2.7E-48 T 12-10-2018 NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 Gene3D G3DSA:3.30.300.20 58 141 2.1E-27 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 Pfam PF13083 KH domain 62 131 8.4E-21 T 12-10-2018 NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 SMART SM00393 127 206 5.4E-19 T 12-10-2018 IPR001374 R3H domain GO:0003676 NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 Gene3D G3DSA:3.30.1370.50 142 208 9.1E-31 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 SMART SM01245 5 57 1.3E-25 T 12-10-2018 IPR032782 Jag, N-terminal NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 Gene3D G3DSA:3.30.30.80 1 57 7.1E-21 T 12-10-2018 IPR038247 Jag, N-terminal domain superfamily NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 Pfam PF14804 Jag N-terminus 7 55 2.6E-21 T 12-10-2018 IPR032782 Jag, N-terminal NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 Pfam PF01424 R3H domain 145 204 5.5E-18 T 12-10-2018 IPR001374 R3H domain GO:0003676 NPD12_123 df0c13eb9e92f82e18cba66d29a4f79d 208 SUPERFAMILY SSF82708 148 203 5.62E-9 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 NPD12_1876 bdff64d404e4e8fc80e8ba0b9a954d0e 527 Gene3D G3DSA:3.40.190.120 362 465 4.5E-101 T 12-10-2018 NPD12_1876 bdff64d404e4e8fc80e8ba0b9a954d0e 527 Gene3D G3DSA:1.10.3720.10 11 205 7.4E-33 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1876 bdff64d404e4e8fc80e8ba0b9a954d0e 527 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 257 522 9.2E-66 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 NPD12_1876 bdff64d404e4e8fc80e8ba0b9a954d0e 527 SUPERFAMILY SSF161098 13 199 5.36E-39 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1876 bdff64d404e4e8fc80e8ba0b9a954d0e 527 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 198 1.3E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1876 bdff64d404e4e8fc80e8ba0b9a954d0e 527 SUPERFAMILY SSF53850 257 525 1.41E-69 T 12-10-2018 NPD12_1876 bdff64d404e4e8fc80e8ba0b9a954d0e 527 Gene3D G3DSA:3.40.190.10 260 521 4.5E-101 T 12-10-2018 NPD12_2490 4e87bcbf9a4d4bef08de1a839f0d2e2b 292 PIRSF PIRSF006230 1 283 9.1E-97 T 12-10-2018 IPR016478 GTPase, MTG1 NPD12_2490 4e87bcbf9a4d4bef08de1a839f0d2e2b 292 Gene3D G3DSA:1.10.1580.10 181 281 6.7E-28 T 12-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily NPD12_2490 4e87bcbf9a4d4bef08de1a839f0d2e2b 292 Pfam PF01926 50S ribosome-binding GTPase 122 194 7.2E-16 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_2490 4e87bcbf9a4d4bef08de1a839f0d2e2b 292 Gene3D G3DSA:3.40.50.300 12 179 4.1E-44 T 12-10-2018 NPD12_2490 4e87bcbf9a4d4bef08de1a839f0d2e2b 292 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 3.9E-108 T 12-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis NPD12_2490 4e87bcbf9a4d4bef08de1a839f0d2e2b 292 SUPERFAMILY SSF52540 9 271 1.94E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_46 fa3b0cb918e59f204fe7788e9186e67f 179 Gene3D G3DSA:3.40.109.10 1 179 1.5E-62 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_46 fa3b0cb918e59f204fe7788e9186e67f 179 SUPERFAMILY SSF55469 3 179 1.31E-57 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_46 fa3b0cb918e59f204fe7788e9186e67f 179 Pfam PF00881 Nitroreductase family 5 157 4.7E-33 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_1212 a4cd25882041c1572ebd6085163b4e0b 187 PIRSF PIRSF000847 2 187 1.1E-23 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 NPD12_1212 a4cd25882041c1572ebd6085163b4e0b 187 Gene3D G3DSA:1.20.120.1760 4 186 4.1E-13 T 12-10-2018 NPD12_1212 a4cd25882041c1572ebd6085163b4e0b 187 Pfam PF01066 CDP-alcohol phosphatidyltransferase 7 78 3.0E-13 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 NPD12_1212 a4cd25882041c1572ebd6085163b4e0b 187 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 56 78 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 NPD12_3396 8c4c92bf576ae9966f73ed17ecb0d38c 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 22.322 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 NPD12_3396 8c4c92bf576ae9966f73ed17ecb0d38c 95 SUPERFAMILY SSF141000 2 93 3.79E-27 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 NPD12_3396 8c4c92bf576ae9966f73ed17ecb0d38c 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 1.8E-14 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 NPD12_3396 8c4c92bf576ae9966f73ed17ecb0d38c 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 5.4E-30 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 NPD12_3396 8c4c92bf576ae9966f73ed17ecb0d38c 95 Gene3D G3DSA:1.10.20.60 1 93 1.9E-25 T 12-10-2018 NPD12_3496 0f7be9ca34d24573822f5db618275f81 301 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3496 0f7be9ca34d24573822f5db618275f81 301 Gene3D G3DSA:3.40.50.300 1 237 1.4E-59 T 12-10-2018 NPD12_3496 0f7be9ca34d24573822f5db618275f81 301 SUPERFAMILY SSF52540 3 218 1.21E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3496 0f7be9ca34d24573822f5db618275f81 301 Pfam PF00005 ABC transporter 20 160 5.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3496 0f7be9ca34d24573822f5db618275f81 301 SMART SM00382 28 211 3.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3363 a29eecebdb156949370a1c88a136fd62 366 SUPERFAMILY SSF53850 38 262 1.3E-35 T 12-10-2018 NPD12_3363 a29eecebdb156949370a1c88a136fd62 366 Gene3D G3DSA:3.40.190.10 39 144 1.6E-11 T 12-10-2018 NPD12_3363 a29eecebdb156949370a1c88a136fd62 366 Pfam PF13379 NMT1-like family 36 265 2.8E-24 T 12-10-2018 NPD12_3363 a29eecebdb156949370a1c88a136fd62 366 Gene3D G3DSA:3.40.190.10 145 333 1.1E-28 T 12-10-2018 NPD12_924 f271032bfbe5adf4faca6ea0fb245443 66 SMART SM00530 7 59 4.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_924 f271032bfbe5adf4faca6ea0fb245443 66 Pfam PF01381 Helix-turn-helix 10 56 9.9E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_924 f271032bfbe5adf4faca6ea0fb245443 66 Gene3D G3DSA:1.10.260.40 4 65 1.3E-9 T 12-10-2018 NPD12_924 f271032bfbe5adf4faca6ea0fb245443 66 SUPERFAMILY SSF47413 6 56 8.57E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 Gene3D G3DSA:1.10.1790.10 75 173 2.3E-29 T 12-10-2018 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 Gene3D G3DSA:1.20.58.1950 230 279 1.1E-13 T 12-10-2018 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 Gene3D G3DSA:2.30.24.10 2 74 2.0E-18 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 Gene3D G3DSA:1.20.890.100 174 229 3.1E-18 T 12-10-2018 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 Pfam PF00874 PRD domain 189 277 5.7E-23 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 Pfam PF00874 PRD domain 83 171 2.5E-23 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 Pfam PF03123 CAT RNA binding domain 9 63 7.2E-17 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 SUPERFAMILY SSF63520 179 277 6.8E-26 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 SUPERFAMILY SSF50151 9 62 7.19E-14 T 12-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 SMART SM01061 9 67 1.0E-21 T 12-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 NPD12_2864 812dcd87bd8863af780abc59c7ce9147 285 SUPERFAMILY SSF63520 63 174 4.05E-30 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 SUPERFAMILY SSF56645 2 238 4.84E-85 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 Gene3D G3DSA:1.10.540.10 1 118 1.0E-38 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 SUPERFAMILY SSF47203 225 376 1.27E-61 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 5.7E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 Gene3D G3DSA:2.40.110.10 119 232 2.9E-42 T 12-10-2018 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 PIRSF PIRSF016578 4 376 1.7E-30 T 12-10-2018 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 Gene3D G3DSA:1.20.140.10 233 377 3.3E-59 T 12-10-2018 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 1.4E-53 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 NPD12_2316 efe78fa2d61b363065710ceefa932af6 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 116 1.9E-34 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 NPD12_1812 5c57937f1e28848c0ba35f608187438b 253 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 49.686 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 NPD12_1812 5c57937f1e28848c0ba35f608187438b 253 Gene3D G3DSA:3.20.20.70 1 253 5.1E-108 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1812 5c57937f1e28848c0ba35f608187438b 253 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 252 9.1E-117 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 NPD12_1812 5c57937f1e28848c0ba35f608187438b 253 Pfam PF00977 Histidine biosynthesis protein 5 235 2.7E-89 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 NPD12_1812 5c57937f1e28848c0ba35f608187438b 253 SUPERFAMILY SSF51366 3 252 4.55E-80 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 Gene3D G3DSA:3.50.50.60 501 621 5.9E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 SUPERFAMILY SSF51905 375 665 7.25E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 SUPERFAMILY SSF51395 5 391 2.14E-91 T 12-10-2018 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 405 638 2.8E-31 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 Gene3D G3DSA:3.40.50.720 406 659 5.9E-63 T 12-10-2018 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 360 1.3E-62 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 Gene3D G3DSA:3.20.20.70 1 404 8.4E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 407 426 6.5E-18 T 12-10-2018 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 527 545 6.5E-18 T 12-10-2018 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 613 629 6.5E-18 T 12-10-2018 NPD12_2299 d86357a9234b4aba576d917898d64c0a 665 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 489 507 6.5E-18 T 12-10-2018 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 48 1123 28.202 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SUPERFAMILY SSF52540 16 364 2.46E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Gene3D G3DSA:3.40.50.300 499 1009 1.8E-245 T 12-10-2018 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Gene3D G3DSA:3.40.50.300 563 802 1.8E-245 T 12-10-2018 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Pfam PF03461 TRCF domain 1025 1114 2.2E-26 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1098 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Pfam PF00270 DEAD/DEAH box helicase 626 785 1.1E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SUPERFAMILY SSF52540 803 1010 3.13E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Gene3D G3DSA:3.40.50.11180 38 336 2.4E-68 T 12-10-2018 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Pfam PF02559 CarD-like/TRCF domain 501 596 1.1E-32 T 12-10-2018 IPR003711 CarD-like/TRCF domain NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SUPERFAMILY SSF141259 494 569 1.96E-24 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Pfam PF00271 Helicase conserved C-terminal domain 827 930 4.4E-19 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SUPERFAMILY SSF52540 380 488 7.21E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SMART SM00982 1024 1123 9.4E-34 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Gene3D G3DSA:3.30.2060.10 140 225 2.4E-68 T 12-10-2018 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Gene3D G3DSA:2.30.30.840 504 562 1.8E-245 T 12-10-2018 NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 Gene3D G3DSA:3.90.1150.50 1020 1168 8.8E-34 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SMART SM00487 621 811 3.1E-37 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SUPERFAMILY SSF143517 1011 1164 1.19E-33 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SMART SM01058 500 597 5.3E-49 T 12-10-2018 IPR003711 CarD-like/TRCF domain NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SMART SM00490 847 931 6.2E-20 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_9 a4f59a32afb6a7efacec5e8cf4420822 1168 SUPERFAMILY SSF52540 544 804 8.46E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_463 b81f409375f4886961515e3e5b52e00a 322 Pfam PF00535 Glycosyl transferase family 2 8 170 8.3E-37 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_463 b81f409375f4886961515e3e5b52e00a 322 SUPERFAMILY SSF53448 6 196 7.88E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_463 b81f409375f4886961515e3e5b52e00a 322 Gene3D G3DSA:3.90.550.10 3 202 5.2E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_1423 8a127f770078b4f2a645eac2769c004c 208 SUPERFAMILY SSF51283 5 207 2.11E-32 T 12-10-2018 IPR036157 dUTPase-like superfamily NPD12_1423 8a127f770078b4f2a645eac2769c004c 208 Pfam PF00692 dUTPase 163 206 4.6E-5 T 12-10-2018 IPR029054 dUTPase-like NPD12_1423 8a127f770078b4f2a645eac2769c004c 208 Pfam PF00692 dUTPase 15 98 3.5E-14 T 12-10-2018 IPR029054 dUTPase-like NPD12_2617 55ca2d1b23d6fd45705bbef8cdf3c4af 255 SUPERFAMILY SSF89550 1 252 2.09E-36 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_2617 55ca2d1b23d6fd45705bbef8cdf3c4af 255 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 229 8.1E-33 T 12-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 NPD12_2617 55ca2d1b23d6fd45705bbef8cdf3c4af 255 Gene3D G3DSA:3.20.20.140 1 252 1.0E-54 T 12-10-2018 NPD12_2617 55ca2d1b23d6fd45705bbef8cdf3c4af 255 Pfam PF02811 PHP domain 3 185 5.6E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 Gene3D G3DSA:3.90.1170.10 1 146 3.7E-59 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.4E-53 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 SUPERFAMILY SSF54686 1 140 8.77E-62 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 PRINTS PR00060 Ribosomal protein L16 signature 88 117 6.7E-39 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 PRINTS PR00060 Ribosomal protein L16 signature 58 87 6.7E-39 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 PRINTS PR00060 Ribosomal protein L16 signature 24 36 6.7E-39 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 PRINTS PR00060 Ribosomal protein L16 signature 42 53 6.7E-39 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 3.1E-62 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.231 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3632 a032a839a941df8651ff0e839e8c4eb6 147 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3331 a4f47ea482d5105981484d311ab11dea 142 Gene3D G3DSA:1.10.10.10 1 82 1.2E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3331 a4f47ea482d5105981484d311ab11dea 142 Pfam PF01475 Ferric uptake regulator family 10 128 7.5E-32 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 NPD12_3331 a4f47ea482d5105981484d311ab11dea 142 Gene3D G3DSA:3.30.1490.190 83 142 6.1E-14 T 12-10-2018 NPD12_3331 a4f47ea482d5105981484d311ab11dea 142 SUPERFAMILY SSF46785 4 132 1.4E-36 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2234 53e5fd7cf78f327a381bc9249a1c0805 198 Pfam PF11193 Protein of unknown function (DUF2812) 15 148 8.8E-31 T 12-10-2018 IPR021359 Protein of unknown function DUF2812 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 SUPERFAMILY SSF56519 55 235 4.71E-44 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Gene3D G3DSA:3.30.10.20 666 721 3.0E-5 T 12-10-2018 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 SUPERFAMILY SSF54184 668 720 2.88E-9 T 12-10-2018 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 SUPERFAMILY SSF56601 187 587 3.59E-99 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Gene3D G3DSA:3.40.710.10 303 500 5.4E-112 T 12-10-2018 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 214 1.4E-22 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Pfam PF03793 PASTA domain 604 659 2.6E-12 T 12-10-2018 IPR005543 PASTA domain NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Pfam PF03793 PASTA domain 668 719 1.9E-9 T 12-10-2018 IPR005543 PASTA domain NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 SUPERFAMILY SSF54184 604 659 9.68E-12 T 12-10-2018 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Pfam PF00905 Penicillin binding protein transpeptidase domain 262 575 1.0E-81 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 SMART SM00740 664 723 3.9E-9 T 12-10-2018 IPR005543 PASTA domain NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 SMART SM00740 600 660 1.9E-16 T 12-10-2018 IPR005543 PASTA domain NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Gene3D G3DSA:3.30.10.20 602 661 2.4E-7 T 12-10-2018 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 16 660 6.8E-267 T 12-10-2018 IPR011927 Stage V sporulation protein D NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Gene3D G3DSA:3.90.1310.30 53 235 1.8E-44 T 12-10-2018 NPD12_1706 64311d70de67e2b0ca084064e45cc2a4 726 Gene3D G3DSA:3.30.450.330 237 583 5.4E-112 T 12-10-2018 NPD12_1143 ce7f505de53f582e2cb02ba8a5ec7bbb 342 Pfam PF17179 4Fe-4S dicluster domain 224 320 7.1E-34 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1143 ce7f505de53f582e2cb02ba8a5ec7bbb 342 SUPERFAMILY SSF46548 222 330 1.74E-14 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_1143 ce7f505de53f582e2cb02ba8a5ec7bbb 342 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1143 ce7f505de53f582e2cb02ba8a5ec7bbb 342 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 225 236 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1143 ce7f505de53f582e2cb02ba8a5ec7bbb 342 TIGRFAM TIGR02910 sulfite_red_A: sulfite reductase, subunit A 1 336 2.5E-187 T 12-10-2018 IPR014259 Sulphite reductase, subunit A NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 227 1.2E-66 T 12-10-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 68 194 1.3E-15 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 Gene3D G3DSA:1.10.150.240 16 100 7.0E-70 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 Gene3D G3DSA:3.40.50.1000 5 223 7.0E-70 T 12-10-2018 IPR023214 HAD superfamily NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 SUPERFAMILY SSF56784 2 228 8.14E-47 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 7.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 7.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 189 202 7.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 7.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 92 201 2.3E-12 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 NPD12_1215 aa2b2b7837a498c548aa6b165969f835 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 1.3E-27 T 12-10-2018 NPD12_2928 7d5bbed887a5783b6eff5a26eaf35aa9 205 Gene3D G3DSA:3.40.50.170 1 204 1.3E-69 T 12-10-2018 NPD12_2928 7d5bbed887a5783b6eff5a26eaf35aa9 205 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 191 30.47 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 NPD12_2928 7d5bbed887a5783b6eff5a26eaf35aa9 205 Pfam PF00551 Formyl transferase 3 185 1.1E-50 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 NPD12_2928 7d5bbed887a5783b6eff5a26eaf35aa9 205 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 195 1.6E-61 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 NPD12_2928 7d5bbed887a5783b6eff5a26eaf35aa9 205 SUPERFAMILY SSF53328 3 201 1.1E-51 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 SUPERFAMILY SSF51055 479 529 4.32E-10 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 Gene3D G3DSA:3.20.20.80 50 376 1.2E-93 T 12-10-2018 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 Pfam PF00704 Glycosyl hydrolases family 18 78 304 4.2E-10 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 SUPERFAMILY SSF51445 53 337 3.75E-22 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 Gene3D G3DSA:2.10.10.20 392 449 1.4E-13 T 12-10-2018 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 Gene3D G3DSA:2.10.10.20 463 530 2.8E-11 T 12-10-2018 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 SMART SM00495 397 441 1.7E-11 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 SMART SM00495 481 529 1.4E-8 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 NPD12_1275 84c17c100c5556dfa6ce2d197c4d7a4c 530 SUPERFAMILY SSF51055 396 447 1.01E-11 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 290 33.874 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 Gene3D G3DSA:3.30.160.40 216 290 5.0E-14 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 SUPERFAMILY SSF54782 215 289 5.1E-18 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 289 1.3E-99 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 PRINTS PR00151 Porphobilinogen deaminase signature 41 61 6.2E-40 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 PRINTS PR00151 Porphobilinogen deaminase signature 139 156 6.2E-40 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 PRINTS PR00151 Porphobilinogen deaminase signature 72 91 6.2E-40 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 PRINTS PR00151 Porphobilinogen deaminase signature 120 137 6.2E-40 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 PRINTS PR00151 Porphobilinogen deaminase signature 225 242 6.2E-40 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 Gene3D G3DSA:3.40.190.10 99 198 4.7E-75 T 12-10-2018 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 205 1.0E-70 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 SUPERFAMILY SSF53850 3 205 3.8E-72 T 12-10-2018 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 Gene3D G3DSA:3.40.190.10 4 204 4.7E-75 T 12-10-2018 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 221 288 2.6E-14 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1105 fd0ff375e52f0d7ab117749f6ac7a14b 290 PIRSF PIRSF001438 1 290 6.0E-104 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 SUPERFAMILY SSF142019 146 386 2.75E-92 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 SUPERFAMILY SSF54862 579 629 3.01E-14 T 12-10-2018 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 SUPERFAMILY SSF52833 40 130 1.23E-23 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 SUPERFAMILY SSF142984 387 470 4.05E-27 T 12-10-2018 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Gene3D G3DSA:3.40.30.10 39 135 5.7E-29 T 12-10-2018 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 194 365 1.9E-47 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 38 116 3.9E-9 T 12-10-2018 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Gene3D G3DSA:3.40.50.11540 199 377 5.5E-78 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Gene3D G3DSA:1.20.1440.230 473 573 3.0E-34 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 SMART SM00928 475 520 9.6E-23 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Gene3D G3DSA:3.30.70.20 576 631 3.4E-14 T 12-10-2018 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 613 624 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Pfam PF00037 4Fe-4S binding domain 607 628 5.0E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 488 499 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 476 560 4.6E-32 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Gene3D G3DSA:3.10.20.600 378 472 6.4E-36 T 12-10-2018 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 Pfam PF10531 SLBB domain 389 437 3.4E-8 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2001 4727c5ee1577ad6105e4da8c861685a5 631 SUPERFAMILY SSF140490 471 573 6.54E-38 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2977 efdddf49bf41480c98d1d97637395dfa 250 Gene3D G3DSA:3.20.20.190 1 243 7.4E-95 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 NPD12_2977 efdddf49bf41480c98d1d97637395dfa 250 SUPERFAMILY SSF51695 3 239 2.28E-82 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 NPD12_2977 efdddf49bf41480c98d1d97637395dfa 250 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 234 3.2E-49 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 NPD12_2923 3dd19f05a9b40ec4574d1fed9ba4d0af 297 Gene3D G3DSA:3.60.15.10 1 229 2.0E-34 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2923 3dd19f05a9b40ec4574d1fed9ba4d0af 297 SMART SM00849 16 204 7.9E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2923 3dd19f05a9b40ec4574d1fed9ba4d0af 297 SUPERFAMILY SSF56281 3 280 1.03E-39 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2923 3dd19f05a9b40ec4574d1fed9ba4d0af 297 Pfam PF00753 Metallo-beta-lactamase superfamily 18 204 1.2E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 215 233 6.6E-30 T 12-10-2018 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 172 195 6.6E-30 T 12-10-2018 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 197 214 6.6E-30 T 12-10-2018 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 53 77 6.6E-30 T 12-10-2018 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 144 168 6.6E-30 T 12-10-2018 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 Gene3D G3DSA:4.10.480.10 210 289 4.7E-31 T 12-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 45 192 5.4E-29 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 Gene3D G3DSA:3.40.50.700 28 209 9.5E-56 T 12-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 PIRSF PIRSF000310 2 290 1.2E-97 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 22 287 2.5E-68 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 210 287 5.9E-31 T 12-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal NPD12_1990 7e2aac179da2be1ed08647779c64ade4 290 SUPERFAMILY SSF56770 33 289 7.2E-74 T 12-10-2018 NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 Gene3D G3DSA:3.40.50.300 318 558 7.2E-70 T 12-10-2018 NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 Pfam PF00664 ABC transporter transmembrane region 12 282 1.3E-32 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 Pfam PF00005 ABC transporter 342 488 3.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 SMART SM00382 350 536 5.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 SUPERFAMILY SSF90123 3 310 5.49E-52 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 SUPERFAMILY SSF52540 319 558 1.41E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_795 33fc58ff63a90ebaaea31d3c1dbb32a5 559 Gene3D G3DSA:1.20.1560.10 1 309 4.0E-45 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1519 23a97acd7ed34960a6f499ed002e5df9 349 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 3 347 38.452 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 NPD12_1519 23a97acd7ed34960a6f499ed002e5df9 349 Gene3D G3DSA:3.40.50.10470 149 349 9.8E-67 T 12-10-2018 NPD12_1519 23a97acd7ed34960a6f499ed002e5df9 349 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 35 337 8.9E-116 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 NPD12_1519 23a97acd7ed34960a6f499ed002e5df9 349 SUPERFAMILY SSF100950 6 342 5.93E-119 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_1519 23a97acd7ed34960a6f499ed002e5df9 349 Gene3D G3DSA:1.20.120.420 2 147 1.3E-45 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 NPD12_1519 23a97acd7ed34960a6f499ed002e5df9 349 Pfam PF01008 Initiation factor 2 subunit family 48 337 1.8E-80 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 NPD12_1519 23a97acd7ed34960a6f499ed002e5df9 349 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 6 336 1.1E-139 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 NPD12_3549 452544422ed0d74c4b93a47d4702aae9 313 SUPERFAMILY SSF52518 3 172 4.32E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_3549 452544422ed0d74c4b93a47d4702aae9 313 Pfam PF02780 Transketolase, C-terminal domain 182 302 6.6E-36 T 12-10-2018 IPR033248 Transketolase, C-terminal domain NPD12_3549 452544422ed0d74c4b93a47d4702aae9 313 Gene3D G3DSA:3.40.50.970 1 181 1.3E-72 T 12-10-2018 NPD12_3549 452544422ed0d74c4b93a47d4702aae9 313 Pfam PF02779 Transketolase, pyrimidine binding domain 4 168 1.5E-44 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain NPD12_3549 452544422ed0d74c4b93a47d4702aae9 313 SMART SM00861 5 170 3.5E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain NPD12_3549 452544422ed0d74c4b93a47d4702aae9 313 SUPERFAMILY SSF52922 179 310 1.96E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_3549 452544422ed0d74c4b93a47d4702aae9 313 Gene3D G3DSA:3.40.50.920 182 312 5.5E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_1013 fb09b7976c48421e314a9e2f2342e3c1 117 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 89 1.3E-30 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 NPD12_1013 fb09b7976c48421e314a9e2f2342e3c1 117 SUPERFAMILY SSF55620 1 115 7.23E-39 T 12-10-2018 NPD12_1013 fb09b7976c48421e314a9e2f2342e3c1 117 PIRSF PIRSF006113 1 117 2.7E-36 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 NPD12_1013 fb09b7976c48421e314a9e2f2342e3c1 117 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 116 1.0E-36 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 NPD12_1013 fb09b7976c48421e314a9e2f2342e3c1 117 Gene3D G3DSA:3.30.479.10 1 72 6.7E-26 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 NPD12_1013 fb09b7976c48421e314a9e2f2342e3c1 117 Gene3D G3DSA:3.30.479.10 73 117 1.0E-10 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 NPD12_3588 2c91710f8739f5d06ad1efff9ef95292 426 Gene3D G3DSA:2.170.120.40 225 311 1.4E-7 T 12-10-2018 NPD12_3588 2c91710f8739f5d06ad1efff9ef95292 426 Gene3D G3DSA:2.170.120.40 138 223 1.1E-12 T 12-10-2018 NPD12_3588 2c91710f8739f5d06ad1efff9ef95292 426 Pfam PF07949 YbbR-like protein 136 220 1.0E-10 T 12-10-2018 IPR012505 YbbR-like NPD12_3588 2c91710f8739f5d06ad1efff9ef95292 426 Pfam PF07949 YbbR-like protein 228 309 3.8E-5 T 12-10-2018 IPR012505 YbbR-like NPD12_3588 2c91710f8739f5d06ad1efff9ef95292 426 Gene3D G3DSA:2.170.120.30 33 137 2.1E-17 T 12-10-2018 NPD12_3588 2c91710f8739f5d06ad1efff9ef95292 426 Gene3D G3DSA:2.170.120.30 329 426 1.7E-11 T 12-10-2018 NPD12_3565 71b0e17e806f79e8b042649991c718d4 198 Pfam PF02633 Creatinine amidohydrolase 2 172 1.0E-22 T 12-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 NPD12_3565 71b0e17e806f79e8b042649991c718d4 198 Gene3D G3DSA:3.40.50.10310 1 178 1.8E-25 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 NPD12_3565 71b0e17e806f79e8b042649991c718d4 198 SUPERFAMILY SSF102215 1 176 8.63E-22 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 NPD12_1988 c21419b587da097912a2fa6e10f878b6 138 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 1 128 1.9E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 NPD12_1988 c21419b587da097912a2fa6e10f878b6 138 Gene3D G3DSA:3.40.50.1450 1 136 3.0E-15 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily NPD12_1988 c21419b587da097912a2fa6e10f878b6 138 Pfam PF01750 Hydrogenase maturation protease 9 127 8.8E-6 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 NPD12_1988 c21419b587da097912a2fa6e10f878b6 138 SUPERFAMILY SSF53163 1 135 6.28E-19 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily NPD12_1721 dad697025e37959b2f771098d3617851 230 Pfam PF01048 Phosphorylase superfamily 2 227 4.1E-53 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 NPD12_1721 dad697025e37959b2f771098d3617851 230 Gene3D G3DSA:3.40.50.1580 1 226 1.6E-66 T 12-10-2018 NPD12_1721 dad697025e37959b2f771098d3617851 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 227 5.9E-53 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 NPD12_1721 dad697025e37959b2f771098d3617851 230 SUPERFAMILY SSF53167 1 227 4.58E-66 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 NPD12_3259 6bafead3956e854e579ae3a95cbf1981 319 Gene3D G3DSA:3.40.50.300 4 319 2.7E-101 T 12-10-2018 NPD12_3259 6bafead3956e854e579ae3a95cbf1981 319 Pfam PF00005 ABC transporter 28 178 3.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3259 6bafead3956e854e579ae3a95cbf1981 319 SUPERFAMILY SSF52540 6 250 9.03E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3259 6bafead3956e854e579ae3a95cbf1981 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 297 5.7E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 NPD12_3259 6bafead3956e854e579ae3a95cbf1981 319 SMART SM00382 36 228 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3259 6bafead3956e854e579ae3a95cbf1981 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 317 5.3E-29 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 NPD12_3259 6bafead3956e854e579ae3a95cbf1981 319 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_31 3641b6938010bf98dcf18ba1bb30a8f0 124 Pfam PF12646 Domain of unknown function (DUF3783) 64 119 7.8E-17 T 12-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 NPD12_31 3641b6938010bf98dcf18ba1bb30a8f0 124 PIRSF PIRSF014543 1 124 4.7E-26 T 12-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 SUPERFAMILY SSF52540 568 824 4.97E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 Gene3D G3DSA:3.40.50.300 831 1032 6.1E-83 T 12-10-2018 NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 SMART SM00490 936 1018 4.7E-25 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 SUPERFAMILY SSF52540 826 1075 3.43E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 Gene3D G3DSA:3.40.50.10810 576 823 1.3E-68 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 Pfam PF08455 Bacterial SNF2 helicase associated 231 603 2.0E-92 T 12-10-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 SMART SM00487 606 793 4.5E-31 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 Pfam PF00271 Helicase conserved C-terminal domain 907 1018 3.7E-20 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 Pfam PF00176 SNF2 family N-terminal domain 627 895 7.2E-62 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 NPD12_1907 d7f592e37144a651c88893fa507317d9 1077 Gene3D G3DSA:1.20.120.850 846 1056 6.1E-83 T 12-10-2018 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 715 729 2.6E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 608 626 2.6E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 671 2.6E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 682 700 2.6E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 SUPERFAMILY SSF81923 4 160 1.31E-38 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 SMART SM01086 774 863 1.5E-35 T 12-10-2018 IPR019489 Clp ATPase, C-terminal NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 638 656 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Gene3D G3DSA:3.40.50.300 347 551 1.7E-71 T 12-10-2018 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Gene3D G3DSA:3.40.50.300 557 772 7.6E-85 T 12-10-2018 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 308 6.3E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 863 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 603 768 1.5E-55 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 149 4.6E-12 T 12-10-2018 IPR004176 Clp, N-terminal NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 68 5.2E-13 T 12-10-2018 IPR004176 Clp, N-terminal NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Gene3D G3DSA:1.10.8.60 774 865 9.2E-28 T 12-10-2018 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 774 853 1.7E-26 T 12-10-2018 IPR019489 Clp ATPase, C-terminal NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 SMART SM00382 604 756 2.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 SMART SM00382 202 348 4.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 SUPERFAMILY SSF52540 553 858 2.02E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Gene3D G3DSA:1.10.1780.10 1 152 3.7E-33 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 298 310 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 Gene3D G3DSA:3.40.50.300 153 346 2.1E-74 T 12-10-2018 NPD12_573 dc49562a4db9740c1ec176ea3484a9b8 866 SUPERFAMILY SSF52540 162 552 7.38E-100 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1234 e8186a10c4120b5b91e594a893351426 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 466 8.7E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1234 e8186a10c4120b5b91e594a893351426 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 8.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 465 8.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 8.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 8.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 SUPERFAMILY SSF158472 195 243 4.05E-6 T 12-10-2018 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 Gene3D G3DSA:1.20.1480.50 159 252 4.9E-10 T 12-10-2018 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 Gene3D G3DSA:3.30.565.10 315 467 2.1E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1234 e8186a10c4120b5b91e594a893351426 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 310 7.8E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 Gene3D G3DSA:1.10.287.130 253 312 5.2E-11 T 12-10-2018 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 SUPERFAMILY SSF47384 232 310 4.9E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 SMART SM00388 247 311 9.5E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1234 e8186a10c4120b5b91e594a893351426 468 SUPERFAMILY SSF55874 300 465 6.29E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1234 e8186a10c4120b5b91e594a893351426 468 SMART SM00387 356 468 4.6E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1234 e8186a10c4120b5b91e594a893351426 468 SMART SM00304 193 246 5.3E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_695 6c94be9f4353894390b50d570f3533a2 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 1.1E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_695 6c94be9f4353894390b50d570f3533a2 228 SUPERFAMILY SSF52172 1 175 6.88E-34 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_695 6c94be9f4353894390b50d570f3533a2 228 SMART SM00862 147 222 3.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_695 6c94be9f4353894390b50d570f3533a2 228 Gene3D G3DSA:1.10.10.10 129 228 2.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_695 6c94be9f4353894390b50d570f3533a2 228 SMART SM00448 2 113 1.4E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_695 6c94be9f4353894390b50d570f3533a2 228 Pfam PF00072 Response regulator receiver domain 4 113 2.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_695 6c94be9f4353894390b50d570f3533a2 228 Gene3D G3DSA:3.40.50.12740 2 128 7.0E-33 T 12-10-2018 NPD12_2910 7de06840d2f2ba16d97cb88922959e56 376 SUPERFAMILY SSF52540 35 198 1.27E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2910 7de06840d2f2ba16d97cb88922959e56 376 TIGRFAM TIGR04066 nat_prod_clost: peptide maturation system protein, TIGR04066 family 6 369 2.0E-148 T 12-10-2018 IPR023823 Conserved hypothetical protein CHP04066, peptide maturation system NPD12_1822 24c5f18503475ceb58b3e356728a4cc6 235 TIGRFAM TIGR03740 galliderm_ABC: lantibiotic protection ABC transporter, ATP-binding subunit 6 228 6.3E-122 T 12-10-2018 IPR022501 Gallidermin ABC transporter, ATP-binding subunit NPD12_1822 24c5f18503475ceb58b3e356728a4cc6 235 Gene3D G3DSA:3.40.50.300 1 235 1.4E-56 T 12-10-2018 NPD12_1822 24c5f18503475ceb58b3e356728a4cc6 235 Pfam PF00005 ABC transporter 21 158 1.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1822 24c5f18503475ceb58b3e356728a4cc6 235 SMART SM00382 30 214 4.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1822 24c5f18503475ceb58b3e356728a4cc6 235 SUPERFAMILY SSF52540 4 210 1.43E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 SUPERFAMILY SSF52540 3 197 1.85E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 SUPERFAMILY SSF52540 297 490 2.86E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 ProSitePatterns PS00211 ABC transporters family signature. 423 437 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 SMART SM00382 334 491 0.068 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 SMART SM00382 30 190 1.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 Pfam PF00005 ABC transporter 326 451 1.2E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 Gene3D G3DSA:3.40.50.300 271 492 3.1E-42 T 12-10-2018 NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 Gene3D G3DSA:3.40.50.300 2 244 4.3E-40 T 12-10-2018 NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 Pfam PF00005 ABC transporter 22 146 3.1E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2898 0e8bdd975278c5e1cf9320d71b3f8581 492 ProSitePatterns PS00211 ABC transporters family signature. 118 132 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_172 ee7168d0eae79067ce3a19d4d473f8d4 230 Gene3D G3DSA:2.40.50.580 1 78 6.7E-22 T 12-10-2018 NPD12_172 ee7168d0eae79067ce3a19d4d473f8d4 230 Gene3D G3DSA:3.40.1350.60 79 230 3.9E-50 T 12-10-2018 NPD12_172 ee7168d0eae79067ce3a19d4d473f8d4 230 Pfam PF03749 Sugar fermentation stimulation protein 13 221 2.5E-76 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein NPD12_172 ee7168d0eae79067ce3a19d4d473f8d4 230 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 4 220 5.9E-64 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein NPD12_172 ee7168d0eae79067ce3a19d4d473f8d4 230 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 230 51.547 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein NPD12_10 1ccfdabd9560128a4dd162ac6610ab59 189 Pfam PF01195 Peptidyl-tRNA hydrolase 3 183 4.0E-61 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 NPD12_10 1ccfdabd9560128a4dd162ac6610ab59 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 183 7.0E-65 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 NPD12_10 1ccfdabd9560128a4dd162ac6610ab59 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 176 36.436 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 NPD12_10 1ccfdabd9560128a4dd162ac6610ab59 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 NPD12_10 1ccfdabd9560128a4dd162ac6610ab59 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 NPD12_10 1ccfdabd9560128a4dd162ac6610ab59 189 SUPERFAMILY SSF53178 1 183 1.44E-67 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 NPD12_10 1ccfdabd9560128a4dd162ac6610ab59 189 Gene3D G3DSA:3.40.50.1470 1 188 1.3E-70 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 NPD12_948 b55eb108fab118edd95320276826eea3 1161 Pfam PF07953 Clostridium neurotoxin, N-terminal receptor binding 816 990 4.9E-60 T 12-10-2018 IPR012928 Clostridium neurotoxin, receptor binding N-terminal GO:0005576|GO:0009405|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 Gene3D G3DSA:2.80.10.50 1007 1161 2.1E-83 T 12-10-2018 NPD12_948 b55eb108fab118edd95320276826eea3 1161 PRINTS PR00760 Bontoxilysin signature 228 244 9.8E-49 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 PRINTS PR00760 Bontoxilysin signature 63 79 9.8E-49 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 PRINTS PR00760 Bontoxilysin signature 181 193 9.8E-49 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 PRINTS PR00760 Bontoxilysin signature 88 110 9.8E-49 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 PRINTS PR00760 Bontoxilysin signature 30 46 9.8E-49 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 PRINTS PR00760 Bontoxilysin signature 6 22 9.8E-49 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 Pfam PF08470 Nontoxic nonhaemagglutinin C-terminal 1000 1161 6.2E-89 T 12-10-2018 IPR013677 Nontoxic nonhaemagglutinin C-terminal NPD12_948 b55eb108fab118edd95320276826eea3 1161 Gene3D G3DSA:1.20.1120.10 471 801 6.6E-176 T 12-10-2018 IPR036248 Clostridium neurotoxin, translocation domain NPD12_948 b55eb108fab118edd95320276826eea3 1161 Gene3D G3DSA:3.90.1240.10 1 470 1.1E-196 T 12-10-2018 NPD12_948 b55eb108fab118edd95320276826eea3 1161 Pfam PF01742 Clostridial neurotoxin zinc protease 1 364 1.2E-92 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_948 b55eb108fab118edd95320276826eea3 1161 Gene3D G3DSA:2.60.120.200 802 1006 3.7E-46 T 12-10-2018 NPD12_948 b55eb108fab118edd95320276826eea3 1161 SUPERFAMILY SSF58091 467 798 1.06E-122 T 12-10-2018 IPR036248 Clostridium neurotoxin, translocation domain NPD12_948 b55eb108fab118edd95320276826eea3 1161 SUPERFAMILY SSF49899 808 990 4.14E-38 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily NPD12_948 b55eb108fab118edd95320276826eea3 1161 SUPERFAMILY SSF55486 1 478 4.94E-158 T 12-10-2018 NPD12_2828 c8dd28450a042caa5cb382a70cf88b68 377 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 212 371 2.8E-21 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 NPD12_2828 c8dd28450a042caa5cb382a70cf88b68 377 Gene3D G3DSA:3.30.300.210 228 374 3.0E-14 T 12-10-2018 IPR038501 Spore germination GerAC superfamily NPD12_2911 975203ef9e181f0d0dcd0541f4b9a3bb 477 Gene3D G3DSA:3.20.20.70 85 463 1.2E-77 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2911 975203ef9e181f0d0dcd0541f4b9a3bb 477 Pfam PF04055 Radical SAM superfamily 94 241 2.5E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2911 975203ef9e181f0d0dcd0541f4b9a3bb 477 SUPERFAMILY SSF102114 88 422 1.2E-46 T 12-10-2018 NPD12_2911 975203ef9e181f0d0dcd0541f4b9a3bb 477 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 357 444 6.4E-7 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_2911 975203ef9e181f0d0dcd0541f4b9a3bb 477 Pfam PF13353 4Fe-4S single cluster domain 95 216 1.3E-10 T 12-10-2018 NPD12_2911 975203ef9e181f0d0dcd0541f4b9a3bb 477 TIGRFAM TIGR04068 rSAM_ocin_clost: Cys-rich peptide radical SAM maturase CcpM 7 467 2.4E-208 T 12-10-2018 IPR024001 Cysteine-rich peptide, radical SAM maturase, CcpM NPD12_2911 975203ef9e181f0d0dcd0541f4b9a3bb 477 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 94 105 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_1366 ed8eb1e620970546aa12e2228d3da90f 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 308 1.1E-136 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 NPD12_1366 ed8eb1e620970546aa12e2228d3da90f 309 SUPERFAMILY SSF53686 3 307 9.04E-104 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme NPD12_1366 ed8eb1e620970546aa12e2228d3da90f 309 Gene3D G3DSA:3.40.50.1100 48 147 4.5E-128 T 12-10-2018 NPD12_1366 ed8eb1e620970546aa12e2228d3da90f 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 297 1.4E-68 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme NPD12_1366 ed8eb1e620970546aa12e2228d3da90f 309 Gene3D G3DSA:3.40.50.1100 7 304 4.5E-128 T 12-10-2018 NPD12_1366 ed8eb1e620970546aa12e2228d3da90f 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 308 8.2E-141 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 NPD12_1366 ed8eb1e620970546aa12e2228d3da90f 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 54 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 NPD12_14 f90458be389469844d55de21c6f11324 319 Gene3D G3DSA:3.40.50.2020 11 306 3.4E-127 T 12-10-2018 NPD12_14 f90458be389469844d55de21c6f11324 319 Pfam PF14572 Phosphoribosyl synthetase-associated domain 209 317 4.5E-22 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 NPD12_14 f90458be389469844d55de21c6f11324 319 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 132 147 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 NPD12_14 f90458be389469844d55de21c6f11324 319 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 2.3E-51 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 NPD12_14 f90458be389469844d55de21c6f11324 319 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 8 318 51.094 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 NPD12_14 f90458be389469844d55de21c6f11324 319 Gene3D G3DSA:3.40.50.2020 151 294 3.4E-127 T 12-10-2018 NPD12_14 f90458be389469844d55de21c6f11324 319 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 8 318 4.4E-127 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 NPD12_14 f90458be389469844d55de21c6f11324 319 SMART SM01400 8 124 1.3E-80 T 12-10-2018 NPD12_14 f90458be389469844d55de21c6f11324 319 SUPERFAMILY SSF53271 73 309 1.78E-67 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_375 fda6d178b6dff8d66bc164f0c138d1e3 155 PIRSF PIRSF029256 2 155 1.9E-65 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 NPD12_375 fda6d178b6dff8d66bc164f0c138d1e3 155 Gene3D G3DSA:3.40.1280.10 1 155 8.5E-65 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal NPD12_375 fda6d178b6dff8d66bc164f0c138d1e3 155 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 152 35.534 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 NPD12_375 fda6d178b6dff8d66bc164f0c138d1e3 155 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 154 1.4E-57 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 NPD12_375 fda6d178b6dff8d66bc164f0c138d1e3 155 SUPERFAMILY SSF75217 3 154 1.9E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases NPD12_375 fda6d178b6dff8d66bc164f0c138d1e3 155 Pfam PF00588 SpoU rRNA Methylase family 3 143 7.7E-33 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 NPD12_3018 b7b416926b98be2fdd68ae4b0544c813 595 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 195 356 1.5E-18 T 12-10-2018 IPR004477 ComEC/Rec2-related protein NPD12_3018 b7b416926b98be2fdd68ae4b0544c813 595 Pfam PF03772 Competence protein 173 419 3.8E-43 T 12-10-2018 IPR004477 ComEC/Rec2-related protein NPD12_1723 175836be16302b8afac99df69a63e956 442 Gene3D G3DSA:3.65.10.10 22 240 1.4E-118 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 NPD12_1723 175836be16302b8afac99df69a63e956 442 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 430 4.2E-103 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 NPD12_1723 175836be16302b8afac99df69a63e956 442 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 441 28.662 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 NPD12_1723 175836be16302b8afac99df69a63e956 442 SUPERFAMILY SSF55205 10 432 1.24E-97 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 NPD12_1723 175836be16302b8afac99df69a63e956 442 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 430 1.5E-90 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 NPD12_1723 175836be16302b8afac99df69a63e956 442 Gene3D G3DSA:3.65.10.10 14 430 1.4E-118 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 NPD12_1723 175836be16302b8afac99df69a63e956 442 ProSitePatterns PS00104 EPSP synthase signature 1. 88 102 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 NPD12_1723 175836be16302b8afac99df69a63e956 442 PIRSF PIRSF000505 3 437 5.1E-107 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 NPD12_400 b92d7a3bf91b372311b8952dc7164ad9 136 Pfam PF14528 LAGLIDADG-like domain 7 84 6.3E-5 T 12-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 NPD12_400 b92d7a3bf91b372311b8952dc7164ad9 136 Gene3D G3DSA:3.10.28.10 1 134 2.7E-17 T 12-10-2018 IPR027434 Homing endonuclease NPD12_400 b92d7a3bf91b372311b8952dc7164ad9 136 SUPERFAMILY SSF55608 2 109 1.55E-13 T 12-10-2018 IPR027434 Homing endonuclease NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SUPERFAMILY SSF50249 318 395 3.77E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Pfam PF12826 Helix-hairpin-helix motif 508 569 1.4E-22 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SMART SM00532 3 445 2.4E-165 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SUPERFAMILY SSF56091 2 315 1.2E-94 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 589 660 1.9E-16 T 12-10-2018 IPR001357 BRCT domain NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Gene3D G3DSA:1.10.287.610 2 69 1.3E-18 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Pfam PF14520 Helix-hairpin-helix domain 443 498 0.005 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SMART SM00278 443 462 0.85 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SMART SM00278 541 560 3.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SMART SM00278 477 496 510.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SMART SM00278 509 528 160.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Gene3D G3DSA:3.30.470.90 70 318 7.3E-73 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Gene3D G3DSA:3.40.50.10190 580 664 7.7E-27 T 12-10-2018 IPR036420 BRCT domain superfamily NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SUPERFAMILY SSF47781 404 581 1.45E-56 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SMART SM00292 589 664 3.1E-11 T 12-10-2018 IPR001357 BRCT domain NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 318 5.6E-91 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 PIRSF PIRSF001604 1 664 8.9E-232 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 331 346 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Hamap MF_01588 DNA ligase [ligA]. 1 663 44.63 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 SUPERFAMILY SSF52113 588 662 1.62E-20 T 12-10-2018 IPR036420 BRCT domain superfamily NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 321 397 2.5E-29 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Gene3D G3DSA:1.10.150.20 429 502 6.5E-23 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Gene3D G3DSA:1.10.150.20 503 579 2.3E-24 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 Gene3D G3DSA:2.40.50.140 319 404 3.8E-29 T 12-10-2018 NPD12_3399 db4b32d26a5e9e3cf26a2594e96ceefc 664 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 659 2.1E-212 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 249 6.9E-64 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 7.7E-27 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 SUPERFAMILY SSF51735 101 250 6.63E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 257 26.668 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 SUPERFAMILY SSF53223 2 100 6.91E-27 T 12-10-2018 NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 Gene3D G3DSA:3.40.50.720 100 233 3.0E-76 T 12-10-2018 NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 Gene3D G3DSA:3.40.50.10860 5 249 3.0E-76 T 12-10-2018 NPD12_2587 1239b94bb9fa0c195f50d99252d291e1 258 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 115 202 1.6E-5 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase NPD12_1791 76dc28a712d5800be4885ef326c1011a 314 Pfam PF08279 HTH domain 5 53 1.8E-14 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_1791 76dc28a712d5800be4885ef326c1011a 314 SUPERFAMILY SSF46785 2 52 1.5E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1791 76dc28a712d5800be4885ef326c1011a 314 Pfam PF13280 WYL domain 143 306 1.6E-34 T 12-10-2018 IPR026881 WYL domain NPD12_1791 76dc28a712d5800be4885ef326c1011a 314 Gene3D G3DSA:1.10.10.10 1 62 1.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1791 76dc28a712d5800be4885ef326c1011a 314 PIRSF PIRSF016838 1 313 1.9E-25 T 12-10-2018 IPR028349 Protein PafC NPD12_594 9c78c2fd45989966e2380fee6749c3b4 281 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 278 3.8E-107 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 NPD12_594 9c78c2fd45989966e2380fee6749c3b4 281 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 1.0E-105 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 NPD12_594 9c78c2fd45989966e2380fee6749c3b4 281 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 79 3.8E-10 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 NPD12_594 9c78c2fd45989966e2380fee6749c3b4 281 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 40.187 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 NPD12_594 9c78c2fd45989966e2380fee6749c3b4 281 SUPERFAMILY SSF52374 1 279 9.3E-107 T 12-10-2018 NPD12_594 9c78c2fd45989966e2380fee6749c3b4 281 Gene3D G3DSA:3.30.1300.10 178 277 1.1E-32 T 12-10-2018 NPD12_594 9c78c2fd45989966e2380fee6749c3b4 281 Gene3D G3DSA:3.40.50.620 1 177 3.6E-76 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3627 55c2337e348600e7c19cc69e38eebc01 179 Pfam PF00281 Ribosomal protein L5 24 80 1.8E-30 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3627 55c2337e348600e7c19cc69e38eebc01 179 Gene3D G3DSA:3.30.1440.10 2 179 3.0E-83 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3627 55c2337e348600e7c19cc69e38eebc01 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.121 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3627 55c2337e348600e7c19cc69e38eebc01 179 PIRSF PIRSF002161 1 179 2.0E-70 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3627 55c2337e348600e7c19cc69e38eebc01 179 SUPERFAMILY SSF55282 3 178 4.94E-79 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3627 55c2337e348600e7c19cc69e38eebc01 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3627 55c2337e348600e7c19cc69e38eebc01 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 3.2E-41 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 40 281 4.3E-76 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 SUPERFAMILY SSF50249 1 64 2.51E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 Gene3D G3DSA:3.40.50.300 63 223 1.6E-46 T 12-10-2018 NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 Pfam PF03193 RsgA GTPase 60 223 2.9E-58 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 SUPERFAMILY SSF52540 66 284 4.26E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 Pfam PF16745 RsgA N-terminal domain 2 57 7.7E-21 T 12-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 Gene3D G3DSA:1.10.40.50 225 291 3.8E-20 T 12-10-2018 NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 Gene3D G3DSA:2.40.50.140 1 62 1.6E-22 T 12-10-2018 NPD12_2550 3888fa28c7db4161d729c7e6205a345b 292 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 1 288 37.753 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 NPD12_3511 ae4e1a32c9ddf4d09e1a2ba9f6438f64 106 Gene3D G3DSA:1.10.10.10 2 106 1.0E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3511 ae4e1a32c9ddf4d09e1a2ba9f6438f64 106 Pfam PF01638 HxlR-like helix-turn-helix 18 105 1.5E-33 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type NPD12_3511 ae4e1a32c9ddf4d09e1a2ba9f6438f64 106 SUPERFAMILY SSF46785 8 105 1.82E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1699 9e3fbf72a72759b9e6e14a6f6a134130 304 Gene3D G3DSA:3.40.50.10800 87 298 1.6E-109 T 12-10-2018 NPD12_1699 9e3fbf72a72759b9e6e14a6f6a134130 304 Gene3D G3DSA:3.40.50.10800 7 282 1.6E-109 T 12-10-2018 NPD12_1699 9e3fbf72a72759b9e6e14a6f6a134130 304 Gene3D G3DSA:3.40.50.10800 171 257 1.6E-109 T 12-10-2018 NPD12_1699 9e3fbf72a72759b9e6e14a6f6a134130 304 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 4 298 1.1E-95 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 NPD12_1699 9e3fbf72a72759b9e6e14a6f6a134130 304 Pfam PF02445 Quinolinate synthetase A protein 8 298 1.2E-112 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 NPD12_1699 9e3fbf72a72759b9e6e14a6f6a134130 304 SUPERFAMILY SSF142754 4 300 4.05E-108 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 NPD12_2962 bc3f25d9a9512d359a85ca0903dd1979 96 Pfam PF01910 Thiamine-binding protein 7 94 3.6E-30 T 12-10-2018 IPR002767 Thiamine-binding protein NPD12_2962 bc3f25d9a9512d359a85ca0903dd1979 96 Gene3D G3DSA:3.30.70.930 1 96 2.8E-38 T 12-10-2018 IPR029756 MTH1187/YkoF-like NPD12_2962 bc3f25d9a9512d359a85ca0903dd1979 96 SUPERFAMILY SSF89957 2 95 1.83E-28 T 12-10-2018 IPR029756 MTH1187/YkoF-like NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 Gene3D G3DSA:3.30.565.10 187 341 1.1E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 SMART SM00388 122 188 2.8E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 SUPERFAMILY SSF55874 178 339 8.25E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 Gene3D G3DSA:1.10.287.130 68 186 2.3E-12 T 12-10-2018 NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 340 9.0E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 321 9.0E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 9.0E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 298 9.0E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 339 5.0E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 SMART SM00387 233 343 9.1E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 Pfam PF00512 His Kinase A (phospho-acceptor) domain 124 188 5.3E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_882 c4ecc84c18337c07749d1180ae9c8d89 345 SUPERFAMILY SSF47384 106 189 1.69E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_887 5829ab4d45b473bf241409333df004ee 278 Gene3D G3DSA:3.20.80.10 134 278 2.1E-27 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_887 5829ab4d45b473bf241409333df004ee 278 Gene3D G3DSA:1.10.10.60 60 115 3.4E-6 T 12-10-2018 NPD12_887 5829ab4d45b473bf241409333df004ee 278 SUPERFAMILY SSF55136 136 278 6.1E-22 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_887 5829ab4d45b473bf241409333df004ee 278 Gene3D G3DSA:1.10.10.60 3 59 6.2E-18 T 12-10-2018 NPD12_887 5829ab4d45b473bf241409333df004ee 278 Pfam PF06445 GyrI-like small molecule binding domain 135 278 1.0E-17 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_887 5829ab4d45b473bf241409333df004ee 278 SMART SM00342 22 105 3.3E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_887 5829ab4d45b473bf241409333df004ee 278 SUPERFAMILY SSF46689 7 56 1.34E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_887 5829ab4d45b473bf241409333df004ee 278 Pfam PF12833 Helix-turn-helix domain 29 106 8.7E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_887 5829ab4d45b473bf241409333df004ee 278 SMART SM00871 133 278 5.7E-15 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_507 1fd2b4597a5ffdd3e0f8e3072c722b9c 468 Gene3D G3DSA:1.20.1740.10 1 463 2.5E-46 T 12-10-2018 NPD12_507 1fd2b4597a5ffdd3e0f8e3072c722b9c 468 Pfam PF13520 Amino acid permease 5 437 1.7E-61 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_507 1fd2b4597a5ffdd3e0f8e3072c722b9c 468 PIRSF PIRSF006060 1 468 1.0E-66 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_3608 02be7ffd5d22513a777d3528c256f616 282 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3608 02be7ffd5d22513a777d3528c256f616 282 SUPERFAMILY SSF52540 4 236 4.33E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3608 02be7ffd5d22513a777d3528c256f616 282 Pfam PF00005 ABC transporter 28 175 2.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3608 02be7ffd5d22513a777d3528c256f616 282 Gene3D G3DSA:3.40.50.300 2 281 3.7E-73 T 12-10-2018 NPD12_3608 02be7ffd5d22513a777d3528c256f616 282 SMART SM00382 37 223 1.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3608 02be7ffd5d22513a777d3528c256f616 282 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 279 3.1E-122 T 12-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 NPD12_1904 f541944bdff14159acae1241a4458824 668 Gene3D G3DSA:3.30.450.20 51 274 2.6E-38 T 12-10-2018 NPD12_1904 f541944bdff14159acae1241a4458824 668 Gene3D G3DSA:1.10.287.950 306 667 3.3E-67 T 12-10-2018 NPD12_1904 f541944bdff14159acae1241a4458824 668 SUPERFAMILY SSF103190 117 183 3.92E-14 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_1904 f541944bdff14159acae1241a4458824 668 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 456 619 9.7E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1904 f541944bdff14159acae1241a4458824 668 SUPERFAMILY SSF58104 331 666 9.59E-67 T 12-10-2018 NPD12_1904 f541944bdff14159acae1241a4458824 668 Gene3D G3DSA:3.30.450.20 63 174 2.6E-38 T 12-10-2018 NPD12_1904 f541944bdff14159acae1241a4458824 668 SMART SM00283 392 667 3.8E-62 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1904 f541944bdff14159acae1241a4458824 668 Pfam PF02743 Cache domain 49 268 5.7E-27 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 368 8.9E-18 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 359 2.1E-142 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 SMART SM00382 37 179 3.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 Pfam PF13177 DNA polymerase III, delta subunit 20 178 4.8E-46 T 12-10-2018 NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 Gene3D G3DSA:3.40.50.300 13 177 1.4E-102 T 12-10-2018 NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 Gene3D G3DSA:1.20.272.10 245 366 1.3E-10 T 12-10-2018 NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 Gene3D G3DSA:1.10.8.60 8 239 1.4E-102 T 12-10-2018 NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 SUPERFAMILY SSF52540 31 221 4.42E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_167 2bfe0433103215bcb21af3c6a45318b8 541 SUPERFAMILY SSF48019 243 365 1.87E-24 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 SUPERFAMILY SSF51161 6 178 1.94E-56 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 PIRSF PIRSF000441 2 195 3.4E-82 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 Gene3D G3DSA:2.160.10.10 70 192 8.5E-38 T 12-10-2018 NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 Gene3D G3DSA:1.10.3130.10 2 69 1.2E-20 T 12-10-2018 NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 129 157 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 154 1.4E-8 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 74 111 3.0E-5 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_364 462021c20d8dc12098b74e8ab43d06eb 198 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 10 169 1.2E-74 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 Pfam PF00717 Peptidase S24-like 448 515 5.3E-13 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 SUPERFAMILY SSF51306 407 529 1.46E-27 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 SUPERFAMILY SSF52540 2 260 3.7E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 Gene3D G3DSA:3.40.50.300 194 277 6.5E-6 T 12-10-2018 NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 445 455 2.7E-5 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 456 467 2.7E-5 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 484 496 2.7E-5 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 273 1.9E-5 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 Gene3D G3DSA:2.10.109.10 414 530 6.6E-36 T 12-10-2018 NPD12_1094 33f9e34e55852a70594900e5e04f4794 531 Gene3D G3DSA:3.40.50.300 1 173 1.7E-8 T 12-10-2018 NPD12_2861 66fe3e1d8bd9b5b5dc06ddd763057a51 244 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 12-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 NPD12_2861 66fe3e1d8bd9b5b5dc06ddd763057a51 244 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 242 2.3E-94 T 12-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 NPD12_2861 66fe3e1d8bd9b5b5dc06ddd763057a51 244 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 44.4 T 12-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 NPD12_2861 66fe3e1d8bd9b5b5dc06ddd763057a51 244 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 27 227 2.2E-18 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 NPD12_2861 66fe3e1d8bd9b5b5dc06ddd763057a51 244 SUPERFAMILY SSF100950 1 243 8.38E-95 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_2861 66fe3e1d8bd9b5b5dc06ddd763057a51 244 Gene3D G3DSA:3.40.50.1360 1 244 9.7E-100 T 12-10-2018 NPD12_459 5d92d957920935b6bb927ec5f903370f 334 Gene3D G3DSA:3.40.1190.20 1 334 5.5E-106 T 12-10-2018 IPR029056 Ribokinase-like NPD12_459 5d92d957920935b6bb927ec5f903370f 334 Pfam PF00294 pfkB family carbohydrate kinase 18 306 1.0E-34 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB NPD12_459 5d92d957920935b6bb927ec5f903370f 334 SUPERFAMILY SSF53613 1 325 5.17E-68 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 Gene3D G3DSA:1.10.10.60 342 394 2.3E-14 T 12-10-2018 NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 5 270 1.3E-114 T 12-10-2018 IPR009215 TIM-barrel domain, IGPS-like NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 Gene3D G3DSA:3.20.20.70 1 250 2.0E-99 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 SUPERFAMILY SSF46689 292 343 3.94E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 Pfam PF12833 Helix-turn-helix domain 315 392 3.2E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 Gene3D G3DSA:1.10.10.60 289 341 2.3E-15 T 12-10-2018 NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 SMART SM00342 309 392 7.0E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 SUPERFAMILY SSF46689 345 393 1.58E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1774 b6dad979bec394cad03a01bc41c684c7 395 SUPERFAMILY SSF51621 1 195 1.13E-72 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 SUPERFAMILY SSF53790 7 224 3.4E-80 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 8 226 37.085 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 Gene3D G3DSA:3.30.950.10 116 231 1.7E-40 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 Gene3D G3DSA:3.40.1010.10 2 115 3.1E-45 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 86 97 - T 12-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 207 5.1E-31 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 9 281 3.3E-83 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 NPD12_219 a35451e4a6bfda1111f5d2eff96b4241 284 PIRSF PIRSF005917 1 284 1.5E-103 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 NPD12_1603 bf7ba26622cbe8771184bf115cbfae7f 228 SMART SM00100 7 129 1.8E-12 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_1603 bf7ba26622cbe8771184bf115cbfae7f 228 SMART SM00419 167 215 3.7E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_1603 bf7ba26622cbe8771184bf115cbfae7f 228 SUPERFAMILY SSF51206 16 143 4.84E-30 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like NPD12_1603 bf7ba26622cbe8771184bf115cbfae7f 228 Gene3D G3DSA:2.60.120.1460 17 222 4.2E-50 T 12-10-2018 NPD12_1603 bf7ba26622cbe8771184bf115cbfae7f 228 Pfam PF13545 Crp-like helix-turn-helix domain 150 221 2.9E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_1603 bf7ba26622cbe8771184bf115cbfae7f 228 Pfam PF00027 Cyclic nucleotide-binding domain 30 112 4.3E-18 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_1603 bf7ba26622cbe8771184bf115cbfae7f 228 SUPERFAMILY SSF46785 147 224 3.54E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1809 dbb83ee25cd439c4a34a765ba1806163 201 Pfam PF00117 Glutamine amidotransferase class-I 4 194 7.3E-24 T 12-10-2018 IPR017926 Glutamine amidotransferase NPD12_1809 dbb83ee25cd439c4a34a765ba1806163 201 Gene3D G3DSA:3.40.50.880 1 200 6.2E-73 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1809 dbb83ee25cd439c4a34a765ba1806163 201 SUPERFAMILY SSF52317 2 199 2.01E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1809 dbb83ee25cd439c4a34a765ba1806163 201 PIRSF PIRSF000495 1 201 8.1E-72 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 NPD12_1809 dbb83ee25cd439c4a34a765ba1806163 201 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 198 1.7E-75 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 NPD12_1809 dbb83ee25cd439c4a34a765ba1806163 201 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 199 36.111 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 210 6.1E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 PIRSF PIRSF002939 2 213 1.2E-109 T 12-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 Pfam PF08281 Sigma-70, region 4 171 206 1.6E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 15 211 1.5E-114 T 12-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 Pfam PF04542 Sigma-70 region 2 38 106 1.1E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 SUPERFAMILY SSF88946 19 106 4.32E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_3658 e1958853d2c83d24875a4748532daa7c 213 SUPERFAMILY SSF88659 124 212 2.35E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_3457 09f4b17b7e2ccf3bdccd98b8237d0154 330 SUPERFAMILY SSF48317 137 296 7.33E-12 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily NPD12_3457 09f4b17b7e2ccf3bdccd98b8237d0154 330 Gene3D G3DSA:1.20.144.10 213 311 5.8E-11 T 12-10-2018 NPD12_3457 09f4b17b7e2ccf3bdccd98b8237d0154 330 Pfam PF14378 PAP2 superfamily 135 287 1.8E-12 T 12-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SMART SM00955 244 573 7.4E-183 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 702 1.2E-282 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SUPERFAMILY SSF50249 50 131 2.29E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SMART SM00316 620 702 1.7E-14 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SMART SM00316 131 195 6.7 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Gene3D G3DSA:2.40.50.140 132 199 3.6E-7 T 12-10-2018 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Gene3D G3DSA:2.40.50.140 56 131 4.2E-19 T 12-10-2018 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SUPERFAMILY SSF50249 122 221 2.95E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_390 e94d56c251541719b1e39d3bce8449af 725 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 54 702 1.4E-225 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Pfam PF00773 RNB domain 244 572 4.6E-118 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SUPERFAMILY SSF50249 620 706 3.43E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Pfam PF08206 Ribonuclease B OB domain 70 128 2.1E-23 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Pfam PF08206 Ribonuclease B OB domain 144 197 2.8E-7 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Pfam PF00575 S1 RNA binding domain 620 691 3.2E-14 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SUPERFAMILY SSF50249 205 619 2.4E-148 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SMART SM00357 134 198 7.3E-8 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 SMART SM00357 69 129 2.4E-13 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Gene3D G3DSA:2.40.50.140 623 724 3.5E-23 T 12-10-2018 NPD12_390 e94d56c251541719b1e39d3bce8449af 725 Hamap MF_01895 Ribonuclease R [rnr]. 21 702 58.754 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 NPD12_3518 11ccfeae6016482ccf0c5acfc2483eee 312 Gene3D G3DSA:3.40.50.720 1 310 4.6E-41 T 12-10-2018 NPD12_3518 11ccfeae6016482ccf0c5acfc2483eee 312 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 231 6.0E-14 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 NPD12_3518 11ccfeae6016482ccf0c5acfc2483eee 312 SUPERFAMILY SSF51735 1 309 5.41E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1032 ba2c297e38cd1b6d4bd89cff425d9a6b 191 Pfam PF13302 Acetyltransferase (GNAT) domain 12 152 3.1E-26 T 12-10-2018 IPR000182 GNAT domain NPD12_1032 ba2c297e38cd1b6d4bd89cff425d9a6b 191 SUPERFAMILY SSF55729 7 178 8.78E-45 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1032 ba2c297e38cd1b6d4bd89cff425d9a6b 191 Gene3D G3DSA:3.40.630.30 7 180 1.2E-45 T 12-10-2018 NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 Gene3D G3DSA:3.60.15.10 6 436 1.4E-146 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 Pfam PF00753 Metallo-beta-lactamase superfamily 11 72 1.6E-10 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 SMART SM00849 13 225 4.2E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 Pfam PF10996 Beta-Casp domain 252 377 1.7E-29 T 12-10-2018 IPR022712 Beta-Casp domain NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 SUPERFAMILY SSF56281 1 464 1.26E-130 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 SMART SM01027 252 377 7.2E-61 T 12-10-2018 IPR022712 Beta-Casp domain NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 Gene3D G3DSA:3.40.50.10890 220 403 1.4E-146 T 12-10-2018 NPD12_1290 43c7ab0442f946cb9b4fcc1577e343a1 502 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 391 453 1.7E-14 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain NPD12_1807 c073d930338de056072df4becd1a69e8 434 Pfam PF00815 Histidinol dehydrogenase 21 429 9.6E-179 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 SUPERFAMILY SSF53720 26 431 3.14E-85 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 NPD12_1807 c073d930338de056072df4becd1a69e8 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 34 428 4.6E-172 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 Gene3D G3DSA:3.40.50.1980 235 351 5.8E-130 T 12-10-2018 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 202 227 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 253 272 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 34 58 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 322 347 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 231 252 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 172 198 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PRINTS PR00083 Histidinol dehydrogenase signature 363 381 2.3E-91 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 231 263 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 PIRSF PIRSF000099 2 432 2.6E-178 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 429 43.82 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 NPD12_1807 c073d930338de056072df4becd1a69e8 434 Gene3D G3DSA:3.40.50.1980 32 233 5.8E-130 T 12-10-2018 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 Gene3D G3DSA:3.30.70.260 265 333 5.9E-26 T 12-10-2018 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 Gene3D G3DSA:3.40.1160.10 1 258 1.3E-78 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 Pfam PF13840 ACT domain 333 393 8.2E-19 T 12-10-2018 IPR027795 CASTOR, ACT domain NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 SUPERFAMILY SSF55021 330 399 2.96E-15 T 12-10-2018 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 SUPERFAMILY SSF55021 254 342 1.98E-5 T 12-10-2018 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 Gene3D G3DSA:3.30.70.260 259 398 5.9E-26 T 12-10-2018 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 Pfam PF00696 Amino acid kinase family 2 235 7.2E-51 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 SUPERFAMILY SSF53633 4 246 7.99E-67 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 397 2.2E-90 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 PIRSF PIRSF000726 1 59 6.2E-9 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 PIRSF PIRSF000726 48 400 9.9E-83 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_2457 b53890398b05bd79314197eb5e28c01f 401 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 100 7.2E-22 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 PIRSF PIRSF006769 1 365 1.3E-139 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 363 1.8E-63 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 Gene3D G3DSA:3.40.430.10 137 364 5.5E-70 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 SUPERFAMILY SSF53927 5 145 8.2E-45 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 Pfam PF01872 RibD C-terminal domain 148 359 6.0E-47 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 SUPERFAMILY SSF53597 146 364 6.49E-56 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 359 1.9E-118 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 NPD12_2921 ff00a21d754e2096d180603296ea6f4c 365 Gene3D G3DSA:3.40.140.10 1 136 1.2E-45 T 12-10-2018 NPD12_1672 0f57faa9b4adc8a72ac047d0daacce69 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_1672 0f57faa9b4adc8a72ac047d0daacce69 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 369 1.3E-105 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 NPD12_1672 0f57faa9b4adc8a72ac047d0daacce69 387 Gene3D G3DSA:3.40.50.1970 1 184 4.5E-57 T 12-10-2018 NPD12_1672 0f57faa9b4adc8a72ac047d0daacce69 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_1672 0f57faa9b4adc8a72ac047d0daacce69 387 SUPERFAMILY SSF56796 2 384 1.19E-117 T 12-10-2018 NPD12_1672 0f57faa9b4adc8a72ac047d0daacce69 387 Gene3D G3DSA:1.20.1090.10 185 386 5.9E-51 T 12-10-2018 NPD12_1438 74826597fae6a9638870a7f3d9f2a730 67 SUPERFAMILY SSF47413 1 66 5.36E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1438 74826597fae6a9638870a7f3d9f2a730 67 SMART SM00530 6 62 6.8E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1438 74826597fae6a9638870a7f3d9f2a730 67 Pfam PF01381 Helix-turn-helix 17 60 7.6E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1438 74826597fae6a9638870a7f3d9f2a730 67 Gene3D G3DSA:1.10.260.40 1 67 2.3E-12 T 12-10-2018 NPD12_394 94e936ce19ffcca11f179f1f577c3600 295 Pfam PF01418 Helix-turn-helix domain, rpiR family 14 70 3.9E-12 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_394 94e936ce19ffcca11f179f1f577c3600 295 Gene3D G3DSA:3.40.50.10490 98 279 4.5E-31 T 12-10-2018 NPD12_394 94e936ce19ffcca11f179f1f577c3600 295 SUPERFAMILY SSF53697 84 264 3.11E-25 T 12-10-2018 NPD12_394 94e936ce19ffcca11f179f1f577c3600 295 Gene3D G3DSA:1.10.10.10 4 77 3.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_394 94e936ce19ffcca11f179f1f577c3600 295 Pfam PF01380 SIS domain 132 243 1.2E-16 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_394 94e936ce19ffcca11f179f1f577c3600 295 SUPERFAMILY SSF46689 14 76 2.51E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1742 d572f00d899996f391ba422a65c19010 290 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 13 235 6.9E-37 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 NPD12_1742 d572f00d899996f391ba422a65c19010 290 SUPERFAMILY SSF51726 16 228 3.14E-28 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_1742 d572f00d899996f391ba422a65c19010 290 Gene3D G3DSA:3.20.20.210 9 250 1.9E-38 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_853 9f3f5831c640798471d31e316bba930c 319 Pfam PF01207 Dihydrouridine synthase (Dus) 5 301 4.1E-33 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 NPD12_853 9f3f5831c640798471d31e316bba930c 319 PIRSF PIRSF006621 1 316 2.7E-59 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 NPD12_853 9f3f5831c640798471d31e316bba930c 319 SUPERFAMILY SSF51395 1 293 3.17E-42 T 12-10-2018 NPD12_853 9f3f5831c640798471d31e316bba930c 319 Gene3D G3DSA:3.20.20.70 1 236 2.6E-57 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_853 9f3f5831c640798471d31e316bba930c 319 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 88 106 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 NPD12_2865 143972e0f667ea03e2495f6823209613 159 SUPERFAMILY SSF51261 4 156 2.27E-54 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_2865 143972e0f667ea03e2495f6823209613 159 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 10 134 1.9E-49 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_2865 143972e0f667ea03e2495f6823209613 159 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 11 131 3.4E-44 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_2865 143972e0f667ea03e2495f6823209613 159 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 73 85 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_2865 143972e0f667ea03e2495f6823209613 159 Gene3D G3DSA:2.70.70.10 5 156 4.6E-55 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_968 0675a0fc893af889b5b42126716c99c3 230 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_968 0675a0fc893af889b5b42126716c99c3 230 SUPERFAMILY SSF52540 3 221 1.49E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_968 0675a0fc893af889b5b42126716c99c3 230 Pfam PF00005 ABC transporter 23 169 1.5E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_968 0675a0fc893af889b5b42126716c99c3 230 Gene3D G3DSA:3.40.50.300 1 227 1.9E-69 T 12-10-2018 NPD12_968 0675a0fc893af889b5b42126716c99c3 230 SMART SM00382 32 218 5.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 SMART SM01134 73 233 1.6E-66 T 12-10-2018 NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 SUPERFAMILY SSF100950 75 233 5.44E-33 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 Gene3D G3DSA:1.10.10.10 1 62 3.5E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 SMART SM00420 6 58 7.7E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.9E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.9E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 1.2E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 SUPERFAMILY SSF46785 5 78 2.84E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2332 dc7acd3daaea85e2f8331f13343db34f 252 Pfam PF00455 DeoR C terminal sensor domain 76 232 9.6E-52 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 SUPERFAMILY SSF55874 414 581 5.63E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 Gene3D G3DSA:3.30.565.10 428 587 2.1E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 SUPERFAMILY SSF47384 345 425 7.06E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 Gene3D G3DSA:1.10.287.130 347 427 9.8E-21 T 12-10-2018 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 SMART SM00387 471 583 5.4E-38 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 Pfam PF00512 His Kinase A (phospho-acceptor) domain 358 425 1.1E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 Gene3D G3DSA:3.30.450.20 215 328 1.3E-11 T 12-10-2018 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 581 4.7E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 SMART SM00388 356 425 1.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 7.6E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 7.6E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 7.6E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 7.6E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 SUPERFAMILY SSF55785 203 328 7.33E-8 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_504 a31d99aa0f323b9b6d31a0bb609bba94 617 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 216 335 4.1E-9 T 12-10-2018 IPR000014 PAS domain NPD12_1138 246eb0aa940d9f314f59b94c6c203862 260 Pfam PF06180 Cobalt chelatase (CbiK) 6 259 2.6E-95 T 12-10-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 NPD12_1138 246eb0aa940d9f314f59b94c6c203862 260 PIRSF PIRSF033579 1 260 2.9E-100 T 12-10-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 NPD12_1138 246eb0aa940d9f314f59b94c6c203862 260 Gene3D G3DSA:3.40.50.1400 7 258 3.0E-98 T 12-10-2018 NPD12_1138 246eb0aa940d9f314f59b94c6c203862 260 Gene3D G3DSA:3.40.50.1400 117 240 3.0E-98 T 12-10-2018 NPD12_1138 246eb0aa940d9f314f59b94c6c203862 260 SUPERFAMILY SSF53800 5 258 2.35E-82 T 12-10-2018 NPD12_2506 8a96e5a46a834e2ec0f2d6158c73e2ec 60 SUPERFAMILY SSF57829 2 56 2.2E-19 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 NPD12_2506 8a96e5a46a834e2ec0f2d6158c73e2ec 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 3 56 18.49 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2506 8a96e5a46a834e2ec0f2d6158c73e2ec 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 3 56 6.7E-27 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2506 8a96e5a46a834e2ec0f2d6158c73e2ec 60 Pfam PF01783 Ribosomal L32p protein family 3 57 3.3E-25 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 Pfam PF00871 Acetokinase family 2 389 6.7E-169 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 Gene3D G3DSA:3.30.420.40 196 397 7.2E-88 T 12-10-2018 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 TIGRFAM TIGR00016 ackA: acetate kinase 1 394 2.7E-167 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 PRINTS PR00471 Acetate kinase family signature 203 224 5.4E-45 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 PRINTS PR00471 Acetate kinase family signature 300 313 5.4E-45 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 PRINTS PR00471 Acetate kinase family signature 173 186 5.4E-45 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 PRINTS PR00471 Acetate kinase family signature 322 338 5.4E-45 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 PRINTS PR00471 Acetate kinase family signature 3 14 5.4E-45 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 PRINTS PR00471 Acetate kinase family signature 376 388 5.4E-45 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 202.034 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 SUPERFAMILY SSF53067 1 196 1.29E-74 T 12-10-2018 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 SUPERFAMILY SSF53067 157 394 9.72E-95 T 12-10-2018 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 Gene3D G3DSA:3.30.420.40 1 195 3.6E-81 T 12-10-2018 NPD12_2508 5d152f1d53605d5f88002f3bbb86dcca 397 PIRSF PIRSF000722 1 397 5.6E-165 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 SUPERFAMILY SSF47203 227 378 1.77E-57 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 PIRSF PIRSF016578 126 379 3.0E-16 T 12-10-2018 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 PIRSF PIRSF016578 6 118 3.8E-8 T 12-10-2018 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 2.7E-50 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 Gene3D G3DSA:1.20.140.10 235 379 9.4E-54 T 12-10-2018 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 Gene3D G3DSA:1.10.540.10 1 120 4.7E-43 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 Gene3D G3DSA:2.40.110.10 121 234 6.1E-44 T 12-10-2018 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 9.0E-37 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 SUPERFAMILY SSF56645 2 242 1.13E-87 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 NPD12_3310 e69520bbdedaacd64cb502687a6aaf63 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.3E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 NPD12_1014 c5188ffda897bb6a3cc7c9e3f83d9760 395 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 168 181 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1014 c5188ffda897bb6a3cc7c9e3f83d9760 395 Pfam PF00809 Pterin binding enzyme 135 377 1.2E-90 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1014 c5188ffda897bb6a3cc7c9e3f83d9760 395 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 133 391 1.5E-106 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 NPD12_1014 c5188ffda897bb6a3cc7c9e3f83d9760 395 SUPERFAMILY SSF51717 126 394 6.54E-100 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1014 c5188ffda897bb6a3cc7c9e3f83d9760 395 Gene3D G3DSA:3.20.20.20 107 395 9.3E-111 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 SUPERFAMILY SSF46894 134 229 1.02E-29 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 Pfam PF00072 Response regulator receiver domain 7 116 3.8E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 1.0E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 SMART SM00448 5 115 1.9E-46 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 Gene3D G3DSA:3.40.50.2300 1 123 1.6E-40 T 12-10-2018 NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 SMART SM00862 153 229 1.4E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 SUPERFAMILY SSF52172 5 124 3.42E-42 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1233 b396c5c0ae1cfb1968423976efc385c3 233 Gene3D G3DSA:1.10.10.10 124 232 5.8E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1677 d540a7b4624b4f473bc6db48f2c3236f 219 Gene3D G3DSA:1.10.3720.10 1 217 9.3E-57 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1677 d540a7b4624b4f473bc6db48f2c3236f 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 5.6E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1677 d540a7b4624b4f473bc6db48f2c3236f 219 SUPERFAMILY SSF161098 13 201 1.7E-47 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1677 d540a7b4624b4f473bc6db48f2c3236f 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 110 3.4E-29 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 NPD12_1365 810a26c5673226f450d2cfa412ce5c5a 145 Gene3D G3DSA:1.10.10.10 1 145 8.0E-46 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1365 810a26c5673226f450d2cfa412ce5c5a 145 Pfam PF02082 Transcriptional regulator 1 83 1.3E-24 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_1365 810a26c5673226f450d2cfa412ce5c5a 145 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 2.2E-34 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_1365 810a26c5673226f450d2cfa412ce5c5a 145 SUPERFAMILY SSF46785 2 133 3.73E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3090 4657a0589d3633054470be37a20dee2a 201 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 200 1.1E-57 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 NPD12_3090 4657a0589d3633054470be37a20dee2a 201 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 201 30.362 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 NPD12_3090 4657a0589d3633054470be37a20dee2a 201 Gene3D G3DSA:3.40.50.620 3 201 1.9E-63 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3090 4657a0589d3633054470be37a20dee2a 201 SUPERFAMILY SSF52374 5 201 6.57E-54 T 12-10-2018 NPD12_3090 4657a0589d3633054470be37a20dee2a 201 Pfam PF01467 Cytidylyltransferase-like 6 175 7.5E-32 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 NPD12_3090 4657a0589d3633054470be37a20dee2a 201 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 65 4.5E-11 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 SUPERFAMILY SSF64288 64 243 2.36E-45 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 Pfam PF07702 UTRA domain 98 238 1.5E-31 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 SUPERFAMILY SSF46785 6 85 1.78E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 SMART SM00866 97 238 1.2E-32 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 Gene3D G3DSA:1.10.10.10 11 79 1.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 1.1E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 SMART SM00345 17 76 1.1E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 Gene3D G3DSA:3.40.1410.10 80 243 1.3E-44 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.0E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2863 90ae618ba0a5eda0f856b543dd069053 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.0E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2803 6968711a5a62bc8ae1507a71e1494533 187 Gene3D G3DSA:3.20.20.400 1 187 4.9E-70 T 12-10-2018 IPR035928 GlpP-like superfamily NPD12_2803 6968711a5a62bc8ae1507a71e1494533 187 SUPERFAMILY SSF110391 11 186 3.53E-60 T 12-10-2018 IPR035928 GlpP-like superfamily NPD12_2803 6968711a5a62bc8ae1507a71e1494533 187 PIRSF PIRSF016897 1 187 6.7E-72 T 12-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 NPD12_2803 6968711a5a62bc8ae1507a71e1494533 187 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 12 185 1.6E-66 T 12-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 NPD12_1611 48c7df0d403173c7c454deef94eca2d5 302 Pfam PF01380 SIS domain 132 211 9.3E-8 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_1611 48c7df0d403173c7c454deef94eca2d5 302 SUPERFAMILY SSF53697 8 250 4.89E-74 T 12-10-2018 NPD12_1611 48c7df0d403173c7c454deef94eca2d5 302 Gene3D G3DSA:1.10.8.1080 222 300 1.3E-25 T 12-10-2018 NPD12_1611 48c7df0d403173c7c454deef94eca2d5 302 Gene3D G3DSA:3.40.50.10490 2 221 1.5E-83 T 12-10-2018 NPD12_1611 48c7df0d403173c7c454deef94eca2d5 302 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 188 205 - T 12-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 NPD12_1611 48c7df0d403173c7c454deef94eca2d5 302 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 9 298 4.2E-130 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 NPD12_1611 48c7df0d403173c7c454deef94eca2d5 302 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 5 298 42.492 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 NPD12_1417 b6cf7be4ef6eb6a9befb34178b9fbf00 90 Pfam PF12652 CotJB protein 9 84 1.2E-26 T 12-10-2018 IPR024207 Spore coat assembly protein CotJB, domain NPD12_1417 b6cf7be4ef6eb6a9befb34178b9fbf00 90 PIRSF PIRSF010606 2 85 1.1E-23 T 12-10-2018 IPR016571 Spore coat assembly protein CotJB NPD12_1504 9b31775312c6b6c9e6030381fa7c50d6 114 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 3 113 1.0E-5 T 12-10-2018 IPR022555 Protein of unknown function, DUF2577 NPD12_1504 9b31775312c6b6c9e6030381fa7c50d6 114 Pfam PF10844 Protein of unknown function (DUF2577) 7 112 1.9E-27 T 12-10-2018 IPR022555 Protein of unknown function, DUF2577 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 SMART SM00977 384 456 1.4E-30 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 SUPERFAMILY SSF82829 215 319 2.48E-10 T 12-10-2018 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 206 1.3E-58 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 Pfam PF11734 TilS substrate C-terminal domain 386 453 1.0E-15 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 SUPERFAMILY SSF52402 2 211 6.28E-55 T 12-10-2018 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 12 296 24.15 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 Pfam PF01171 PP-loop family 20 201 2.1E-51 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 Gene3D G3DSA:3.40.50.620 1 212 4.9E-68 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 SUPERFAMILY SSF56037 373 457 8.89E-24 T 12-10-2018 NPD12_3700 1bd3b140fe907bb534444687ab0064c2 468 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 384 429 3.5E-19 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 NPD12_229 516f34ae2736548f7a6392a37dddcd86 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 421 7.1E-84 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_229 516f34ae2736548f7a6392a37dddcd86 445 Pfam PF01554 MatE 245 406 7.3E-32 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_229 516f34ae2736548f7a6392a37dddcd86 445 Pfam PF01554 MatE 17 179 1.9E-29 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_229 516f34ae2736548f7a6392a37dddcd86 445 PIRSF PIRSF006603 2 445 2.4E-96 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 PIRSF PIRSF001259 3 401 6.9E-185 T 12-10-2018 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 SUPERFAMILY SSF142695 205 375 1.57E-72 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 9 199 1.3E-84 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 SUPERFAMILY SSF55821 3 203 3.43E-84 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 Gene3D G3DSA:3.90.870.10 1 206 5.0E-88 T 12-10-2018 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 213 398 5.2E-84 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 200 1.5E-78 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 3 204 38.619 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 Pfam PF00925 GTP cyclohydrolase II 213 374 8.2E-76 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 4 396 55.628 T 12-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 205 400 43.186 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 NPD12_2919 ab00ffe42be69515e2180f7318a54f2c 401 Gene3D G3DSA:3.40.50.10990 207 378 4.2E-78 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 SUPERFAMILY SSF46785 7 140 4.36E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 Gene3D G3DSA:1.10.10.10 4 141 1.8E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 SMART SM00347 25 125 2.2E-24 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 5.8E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 5.8E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 5.8E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 5.8E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2373 6ec7ab8dd9a720523a11e24f6ec31cfc 143 Pfam PF01047 MarR family 32 89 7.8E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 SUPERFAMILY SSF51569 1 290 1.99E-98 T 12-10-2018 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 PIRSF PIRSF001365 1 292 5.2E-90 T 12-10-2018 IPR002220 DapA-like GO:0016829 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 288 62.055 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 1.8E-90 T 12-10-2018 IPR002220 DapA-like GO:0016829 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 1.3E-31 T 12-10-2018 IPR002220 DapA-like GO:0016829 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 1.3E-31 T 12-10-2018 IPR002220 DapA-like GO:0016829 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 1.3E-31 T 12-10-2018 IPR002220 DapA-like GO:0016829 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 1.3E-31 T 12-10-2018 IPR002220 DapA-like GO:0016829 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 Gene3D G3DSA:3.20.20.70 2 292 2.8E-122 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 SMART SM01130 3 290 3.9E-131 T 12-10-2018 IPR002220 DapA-like GO:0016829 NPD12_3265 ca1f2e25ef9088a42f1949f830f7b87c 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 8 288 7.5E-106 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 NPD12_3289 1ed78d352a049e3de3af09f53ce03057 195 Pfam PF01613 Flavin reductase like domain 14 146 1.7E-23 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 NPD12_3289 1ed78d352a049e3de3af09f53ce03057 195 Gene3D G3DSA:2.30.110.10 1 195 5.2E-53 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_3289 1ed78d352a049e3de3af09f53ce03057 195 SMART SM00903 11 156 1.8E-20 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 NPD12_3289 1ed78d352a049e3de3af09f53ce03057 195 SUPERFAMILY SSF50475 9 174 1.52E-42 T 12-10-2018 NPD12_1606 fb2b835a41071048f68683e8b8cca601 332 Gene3D G3DSA:1.10.3470.10 1 332 2.3E-104 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1606 fb2b835a41071048f68683e8b8cca601 332 SUPERFAMILY SSF81345 4 328 5.89E-85 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1606 fb2b835a41071048f68683e8b8cca601 332 Pfam PF01032 FecCD transport family 14 328 4.6E-99 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_2778 951c3eb8b1189267a199f57181019710 131 Gene3D G3DSA:2.30.30.40 4 125 8.8E-37 T 12-10-2018 NPD12_2778 951c3eb8b1189267a199f57181019710 131 Gene3D G3DSA:2.40.50.180 19 131 8.8E-37 T 12-10-2018 NPD12_2778 951c3eb8b1189267a199f57181019710 131 SMART SM00260 1 131 1.8E-20 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_2778 951c3eb8b1189267a199f57181019710 131 SUPERFAMILY SSF50341 1 131 7.98E-32 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 NPD12_2778 951c3eb8b1189267a199f57181019710 131 Pfam PF01584 CheW-like domain 2 131 7.2E-31 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_1360 b33919b9d64d6329bbb08555259a357c 264 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 257 2.1E-59 T 12-10-2018 NPD12_1360 b33919b9d64d6329bbb08555259a357c 264 SUPERFAMILY SSF56784 1 260 1.65E-64 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1360 b33919b9d64d6329bbb08555259a357c 264 Gene3D G3DSA:3.30.1240.10 83 187 6.2E-66 T 12-10-2018 NPD12_1360 b33919b9d64d6329bbb08555259a357c 264 Gene3D G3DSA:3.40.50.1000 5 257 6.2E-66 T 12-10-2018 IPR023214 HAD superfamily NPD12_1360 b33919b9d64d6329bbb08555259a357c 264 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 230 1.8E-26 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 NPD12_1360 b33919b9d64d6329bbb08555259a357c 264 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 12-10-2018 NPD12_1360 b33919b9d64d6329bbb08555259a357c 264 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 257 9.0E-52 T 12-10-2018 IPR000150 Cof family GO:0016787 NPD12_1273 b4870c1eac7ba7d3bbf5345b336da434 131 Pfam PF07238 PilZ domain 20 128 2.8E-13 T 12-10-2018 IPR009875 PilZ domain GO:0035438 NPD12_1273 b4870c1eac7ba7d3bbf5345b336da434 131 SUPERFAMILY SSF141371 46 128 3.53E-6 T 12-10-2018 NPD12_1273 b4870c1eac7ba7d3bbf5345b336da434 131 Gene3D G3DSA:2.40.10.220 21 131 5.0E-8 T 12-10-2018 NPD12_3171 435104ab64b22b8327d487883e5812b9 287 PRINTS PR01755 Bacterial translocase SecF protein signature 29 44 1.9E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial NPD12_3171 435104ab64b22b8327d487883e5812b9 287 PRINTS PR01755 Bacterial translocase SecF protein signature 219 234 1.9E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial NPD12_3171 435104ab64b22b8327d487883e5812b9 287 PRINTS PR01755 Bacterial translocase SecF protein signature 139 153 1.9E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial NPD12_3171 435104ab64b22b8327d487883e5812b9 287 PRINTS PR01755 Bacterial translocase SecF protein signature 187 205 1.9E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial NPD12_3171 435104ab64b22b8327d487883e5812b9 287 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 2 281 27.363 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 NPD12_3171 435104ab64b22b8327d487883e5812b9 287 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 30 270 7.3E-76 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 NPD12_3171 435104ab64b22b8327d487883e5812b9 287 Gene3D G3DSA:1.20.1640.10 85 283 1.4E-8 T 12-10-2018 NPD12_3171 435104ab64b22b8327d487883e5812b9 287 Pfam PF02355 Protein export membrane protein 103 279 7.3E-66 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial NPD12_3171 435104ab64b22b8327d487883e5812b9 287 Pfam PF07549 SecD/SecF GG Motif 25 46 2.7E-7 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site NPD12_3171 435104ab64b22b8327d487883e5812b9 287 SUPERFAMILY SSF82866 79 280 2.75E-36 T 12-10-2018 NPD12_3171 435104ab64b22b8327d487883e5812b9 287 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 53 267 6.4E-53 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 354 9.2E-177 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 SUPERFAMILY SSF53067 3 173 9.06E-76 T 12-10-2018 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 PRINTS PR00471 Acetate kinase family signature 179 200 2.5E-18 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 PRINTS PR00471 Acetate kinase family signature 274 287 2.5E-18 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 PRINTS PR00471 Acetate kinase family signature 297 313 2.5E-18 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 PRINTS PR00471 Acetate kinase family signature 5 16 2.5E-18 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 Pfam PF00871 Acetokinase family 4 352 6.7E-86 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 179 196 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 SUPERFAMILY SSF53067 119 347 2.76E-55 T 12-10-2018 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 Gene3D G3DSA:3.30.420.40 5 355 6.0E-162 T 12-10-2018 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 PIRSF PIRSF036458 1 356 1.5E-176 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 Hamap MF_00542 Probable butyrate kinase [buk]. 1 356 175.814 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 NPD12_3584 590f6a8fe82201d97cd5651654e9f8cf 356 Gene3D G3DSA:3.30.420.40 137 332 6.0E-162 T 12-10-2018 NPD12_2599 d03b9148f06602df7132f9edc81ecd3c 556 Gene3D G3DSA:3.40.710.10 225 555 2.4E-65 T 12-10-2018 NPD12_2599 d03b9148f06602df7132f9edc81ecd3c 556 SUPERFAMILY SSF56601 193 552 3.82E-65 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_2599 d03b9148f06602df7132f9edc81ecd3c 556 Pfam PF00905 Penicillin binding protein transpeptidase domain 255 549 4.3E-47 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 Gene3D G3DSA:3.30.565.10 155 296 4.8E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 SUPERFAMILY SSF55874 158 285 2.23E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 Pfam PF00512 His Kinase A (phospho-acceptor) domain 91 148 1.9E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 196 285 1.0E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 Gene3D G3DSA:1.10.287.130 26 144 3.9E-18 T 12-10-2018 NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 SMART SM00387 195 302 2.0E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 SMART SM00388 86 149 1.6E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_409 d3d638f6e98af02fc21f32977714b5c0 302 SUPERFAMILY SSF47384 79 149 1.51E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2891 a8ac1ca690cb00209e4cc1029d39f566 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 132 191 1.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_2891 a8ac1ca690cb00209e4cc1029d39f566 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 190 1.9E-20 T 12-10-2018 NPD12_2891 a8ac1ca690cb00209e4cc1029d39f566 223 SUPERFAMILY SSF56784 1 222 1.08E-40 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_2891 a8ac1ca690cb00209e4cc1029d39f566 223 Gene3D G3DSA:1.10.150.240 16 92 1.2E-40 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 NPD12_2891 a8ac1ca690cb00209e4cc1029d39f566 223 Gene3D G3DSA:3.40.50.1000 4 194 1.2E-40 T 12-10-2018 IPR023214 HAD superfamily NPD12_701 af1e3efa25c114d22948240a5fb86158 154 Pfam PF01037 Lrp/AsnC ligand binding domain 74 146 3.7E-18 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain NPD12_701 af1e3efa25c114d22948240a5fb86158 154 SMART SM00344 8 115 7.2E-41 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 NPD12_701 af1e3efa25c114d22948240a5fb86158 154 Gene3D G3DSA:1.10.10.10 6 59 2.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_701 af1e3efa25c114d22948240a5fb86158 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 2.4E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 NPD12_701 af1e3efa25c114d22948240a5fb86158 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 2.4E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 NPD12_701 af1e3efa25c114d22948240a5fb86158 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 2.4E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 NPD12_701 af1e3efa25c114d22948240a5fb86158 154 SUPERFAMILY SSF54909 69 151 6.17E-20 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel NPD12_701 af1e3efa25c114d22948240a5fb86158 154 SUPERFAMILY SSF46785 8 68 5.17E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_701 af1e3efa25c114d22948240a5fb86158 154 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 5.5E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 NPD12_701 af1e3efa25c114d22948240a5fb86158 154 Gene3D G3DSA:3.30.70.920 60 142 8.2E-32 T 12-10-2018 NPD12_872 f82d08d00d0962f5baac3e9a46f89460 130 Pfam PF01597 Glycine cleavage H-protein 7 125 3.3E-42 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate NPD12_872 f82d08d00d0962f5baac3e9a46f89460 130 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 40.444 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 NPD12_872 f82d08d00d0962f5baac3e9a46f89460 130 Gene3D G3DSA:2.40.50.100 1 130 1.2E-48 T 12-10-2018 NPD12_872 f82d08d00d0962f5baac3e9a46f89460 130 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 5 125 5.9E-44 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 NPD12_872 f82d08d00d0962f5baac3e9a46f89460 130 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 NPD12_872 f82d08d00d0962f5baac3e9a46f89460 130 SUPERFAMILY SSF51230 3 125 2.62E-40 T 12-10-2018 IPR011053 Single hybrid motif NPD12_3346 4cf975e5cabdaab116366be59dbf8dca 191 SUPERFAMILY SSF53271 9 149 8.8E-39 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_3346 4cf975e5cabdaab116366be59dbf8dca 191 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 5 188 1.6E-70 T 12-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_3346 4cf975e5cabdaab116366be59dbf8dca 191 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 191 25.348 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3346 4cf975e5cabdaab116366be59dbf8dca 191 Gene3D G3DSA:3.40.50.2020 4 191 6.7E-57 T 12-10-2018 NPD12_3346 4cf975e5cabdaab116366be59dbf8dca 191 Pfam PF00156 Phosphoribosyl transferase domain 42 164 3.4E-13 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 163 1.3E-67 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 Gene3D G3DSA:3.10.20.80 1 69 3.1E-33 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 Gene3D G3DSA:3.30.110.10 70 164 4.2E-35 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 SUPERFAMILY SSF55200 76 163 2.88E-29 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 70 7.6E-33 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 77 161 3.9E-35 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 164 27.708 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 ProSitePatterns PS00938 Initiation factor 3 signature. 52 65 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 NPD12_3245 a5f8d2fa14762fc716ee0322c1f8368c 164 SUPERFAMILY SSF54364 1 72 6.54E-29 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 NPD12_447 57d81c096ef72b234844eb9e8ac92eca 253 Gene3D G3DSA:1.10.10.10 5 76 1.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_447 57d81c096ef72b234844eb9e8ac92eca 253 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 72 1.2E-9 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_447 57d81c096ef72b234844eb9e8ac92eca 253 Gene3D G3DSA:3.40.50.10490 88 252 3.0E-28 T 12-10-2018 NPD12_447 57d81c096ef72b234844eb9e8ac92eca 253 Pfam PF01380 SIS domain 118 216 4.2E-12 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_447 57d81c096ef72b234844eb9e8ac92eca 253 SUPERFAMILY SSF53697 93 249 1.13E-23 T 12-10-2018 NPD12_447 57d81c096ef72b234844eb9e8ac92eca 253 SUPERFAMILY SSF46689 13 78 2.69E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2123 58657006c3cd94a6c9f576359035ac0d 208 Gene3D G3DSA:3.40.50.360 1 190 2.3E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2123 58657006c3cd94a6c9f576359035ac0d 208 Pfam PF03358 NADPH-dependent FMN reductase 1 152 4.3E-28 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_2123 58657006c3cd94a6c9f576359035ac0d 208 SUPERFAMILY SSF52218 1 185 5.12E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Gene3D G3DSA:2.40.50.140 104 185 1.0E-8 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SUPERFAMILY SSF50249 264 359 1.93E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Gene3D G3DSA:2.40.50.140 279 362 6.7E-30 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Pfam PF00575 S1 RNA binding domain 22 93 1.5E-6 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Pfam PF00575 S1 RNA binding domain 195 266 1.6E-23 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Pfam PF00575 S1 RNA binding domain 280 352 1.5E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Pfam PF00575 S1 RNA binding domain 110 175 4.7E-7 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SUPERFAMILY SSF50249 110 191 3.62E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SMART SM00316 22 93 6.6E-9 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SMART SM00316 281 352 2.4E-27 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SMART SM00316 109 177 1.3E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SMART SM00316 196 266 1.5E-27 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SUPERFAMILY SSF50249 6 115 4.0E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Gene3D G3DSA:2.40.50.140 9 103 1.0E-13 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 SUPERFAMILY SSF50249 195 283 1.36E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 218 239 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 24 42 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 114 130 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 335 353 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 132 149 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 296 315 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 90 109 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 42 56 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 PRINTS PR00681 Ribosomal protein S1 signature 161 181 8.8E-51 T 12-10-2018 NPD12_1346 56e9cf2d55a354b6ac1f172b83597948 387 Gene3D G3DSA:2.40.50.140 188 278 2.1E-28 T 12-10-2018 NPD12_1361 8a7b6fc4fea04322474a01b3ad1cfd88 168 Pfam PF00583 Acetyltransferase (GNAT) family 44 133 3.4E-14 T 12-10-2018 IPR000182 GNAT domain NPD12_1361 8a7b6fc4fea04322474a01b3ad1cfd88 168 SUPERFAMILY SSF55729 25 143 3.49E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1361 8a7b6fc4fea04322474a01b3ad1cfd88 168 Gene3D G3DSA:3.40.630.30 48 146 1.4E-22 T 12-10-2018 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 476 8.3E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 SUPERFAMILY SSF47384 243 323 4.51E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 5.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 5.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 5.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 5.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 SMART SM00387 368 475 6.6E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 SUPERFAMILY SSF158472 184 231 3.4E-8 T 12-10-2018 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 Pfam PF00672 HAMP domain 185 231 2.9E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 Gene3D G3DSA:3.30.565.10 328 477 2.9E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 SMART SM00388 257 323 3.9E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 SUPERFAMILY SSF55874 314 476 1.31E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 Gene3D G3DSA:1.10.287.130 250 324 2.6E-16 T 12-10-2018 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 SMART SM00304 183 235 3.5E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 322 1.6E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2130 0ca811f4a6413a76a6846ab0a2501119 477 Gene3D G3DSA:1.20.1480.50 150 241 1.5E-10 T 12-10-2018 NPD12_943 eaf122e45f95bcf2ed194acaea8cb928 490 Pfam PF06597 Clostridium P-47 protein 5 483 1.5E-65 T 12-10-2018 IPR010567 Clostridium P47 protein NPD12_3342 37889f878f2589f1acff6074f82bf618 194 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 9.8E-55 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 NPD12_3342 37889f878f2589f1acff6074f82bf618 194 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 9.8E-55 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 NPD12_3342 37889f878f2589f1acff6074f82bf618 194 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 9.8E-55 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 NPD12_3342 37889f878f2589f1acff6074f82bf618 194 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 9.8E-55 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 NPD12_3342 37889f878f2589f1acff6074f82bf618 194 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 9.8E-55 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 NPD12_3342 37889f878f2589f1acff6074f82bf618 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 6.7E-107 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 NPD12_3342 37889f878f2589f1acff6074f82bf618 194 Pfam PF00574 Clp protease 13 192 6.4E-89 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA NPD12_3342 37889f878f2589f1acff6074f82bf618 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 12-10-2018 IPR018215 ClpP, Ser active site NPD12_3342 37889f878f2589f1acff6074f82bf618 194 Gene3D G3DSA:3.90.226.10 1 194 1.0E-85 T 12-10-2018 NPD12_3342 37889f878f2589f1acff6074f82bf618 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 12-10-2018 IPR033135 ClpP, histidine active site NPD12_3342 37889f878f2589f1acff6074f82bf618 194 SUPERFAMILY SSF52096 10 192 1.44E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily NPD12_3342 37889f878f2589f1acff6074f82bf618 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.102 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 NPD12_2370 1f136670e862c927ac15076b6f75fa7a 467 PIRSF PIRSF006060 1 466 2.6E-46 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2370 1f136670e862c927ac15076b6f75fa7a 467 Pfam PF13520 Amino acid permease 11 430 2.9E-29 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2370 1f136670e862c927ac15076b6f75fa7a 467 Gene3D G3DSA:1.20.1740.10 4 466 3.3E-22 T 12-10-2018 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 48.094 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.2E-84 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 Gene3D G3DSA:3.40.50.460 142 251 6.2E-114 T 12-10-2018 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 Pfam PF00365 Phosphofructokinase 4 275 6.2E-110 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 SUPERFAMILY SSF53784 2 316 1.7E-116 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 PIRSF PIRSF000532 1 318 6.4E-121 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 299 3.3E-131 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 NPD12_3528 c07a881e1b071bdb01f7d402c21a5120 319 Gene3D G3DSA:3.40.50.450 4 286 6.2E-114 T 12-10-2018 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Gene3D G3DSA:1.10.10.650 1 108 1.1E-37 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 SUPERFAMILY SSF50249 632 718 1.72E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 SUPERFAMILY SSF158832 1 308 1.44E-112 T 12-10-2018 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Gene3D G3DSA:1.10.150.310 490 627 4.4E-47 T 12-10-2018 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 SMART SM00316 646 717 1.4E-27 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Gene3D G3DSA:2.40.50.140 633 718 3.7E-28 T 12-10-2018 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 SUPERFAMILY SSF47781 551 629 4.45E-16 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 SMART SM00732 313 415 1.1E-36 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Gene3D G3DSA:3.30.420.140 312 442 3.1E-152 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Pfam PF00575 S1 RNA binding domain 646 717 4.6E-20 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Gene3D G3DSA:1.10.3500.10 111 489 3.1E-152 T 12-10-2018 IPR023323 Tex-like domain superfamily NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Pfam PF12836 Helix-hairpin-helix motif 482 546 4.5E-30 T 12-10-2018 NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Pfam PF16921 Tex protein YqgF-like domain 313 442 1.6E-52 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 Pfam PF09371 Tex-like protein N-terminal domain 8 192 1.4E-69 T 12-10-2018 IPR018974 Tex-like protein, N-terminal NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 SUPERFAMILY SSF47781 461 547 1.09E-27 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_334 754085ce02fe7fe6e5fc6c129fb576e5 718 SUPERFAMILY SSF53098 309 460 1.21E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_391 36987e280d150c90820aa435117f7a08 252 Pfam PF01975 Survival protein SurE 3 187 6.7E-60 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 NPD12_391 36987e280d150c90820aa435117f7a08 252 Gene3D G3DSA:3.40.1210.10 1 251 8.7E-85 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 NPD12_391 36987e280d150c90820aa435117f7a08 252 SUPERFAMILY SSF64167 1 250 6.41E-75 T 12-10-2018 NPD12_391 36987e280d150c90820aa435117f7a08 252 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 252 32.627 T 12-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 NPD12_391 36987e280d150c90820aa435117f7a08 252 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 238 4.2E-66 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 NPD12_2589 d4b51e2f1aa8fd732dbd9077f01ba97d 59 SUPERFAMILY SSF140500 3 55 3.92E-7 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 NPD12_2589 d4b51e2f1aa8fd732dbd9077f01ba97d 59 Pfam PF09388 Spo0E like sporulation regulatory protein 7 50 1.7E-10 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 Pfam PF01514 Secretory protein of YscJ/FliF family 30 217 3.2E-64 T 12-10-2018 IPR006182 Secretory protein YscJ/FliF NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 Gene3D G3DSA:3.30.300.30 119 218 3.5E-10 T 12-10-2018 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 5 524 1.6E-87 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 PRINTS PR01009 Flagellar M-ring protein signature 269 287 7.0E-30 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 PRINTS PR01009 Flagellar M-ring protein signature 150 164 7.0E-30 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 PRINTS PR01009 Flagellar M-ring protein signature 341 365 7.0E-30 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 PRINTS PR01009 Flagellar M-ring protein signature 118 136 7.0E-30 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 PRINTS PR01009 Flagellar M-ring protein signature 193 211 7.0E-30 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 Pfam PF08345 Flagellar M-ring protein C-terminal 256 404 1.9E-33 T 12-10-2018 IPR013556 Flagellar M-ring C-terminal NPD12_2712 9d3ab0b8776c3ff236fa2731e268a5a2 526 PIRSF PIRSF004862 1 526 6.7E-131 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 471 629 4.2E-40 T 12-10-2018 IPR000160 GGDEF domain NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 Pfam PF00563 EAL domain 646 880 9.0E-76 T 12-10-2018 IPR001633 EAL domain NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 Gene3D G3DSA:3.30.450.20 365 461 1.8E-6 T 12-10-2018 NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 SMART SM00052 640 885 2.1E-106 T 12-10-2018 IPR001633 EAL domain NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 SUPERFAMILY SSF55073 477 631 7.53E-43 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 SMART SM00304 283 336 0.0087 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 SUPERFAMILY SSF141868 645 889 1.44E-87 T 12-10-2018 IPR035919 EAL domain superfamily NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 Pfam PF00990 Diguanylate cyclase, GGDEF domain 472 624 9.7E-43 T 12-10-2018 IPR000160 GGDEF domain NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 Pfam PF05228 CHASE4 domain 53 200 1.4E-27 T 12-10-2018 IPR007892 CHASE4 NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 SMART SM00267 461 630 7.1E-51 T 12-10-2018 IPR000160 GGDEF domain NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 Gene3D G3DSA:3.30.70.270 466 641 5.9E-56 T 12-10-2018 NPD12_521 ca00e71414bcd6663614102f1bb16fdf 892 Gene3D G3DSA:3.20.20.450 642 892 4.9E-95 T 12-10-2018 IPR035919 EAL domain superfamily NPD12_1062 416b726192dc141b586fa16db02b9c25 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 1.4E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1062 416b726192dc141b586fa16db02b9c25 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 1.4E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1062 416b726192dc141b586fa16db02b9c25 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 1.4E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1062 416b726192dc141b586fa16db02b9c25 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 303 317 1.4E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1062 416b726192dc141b586fa16db02b9c25 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 437 449 1.4E-16 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1062 416b726192dc141b586fa16db02b9c25 473 Gene3D G3DSA:3.20.20.80 2 473 3.8E-156 T 12-10-2018 NPD12_1062 416b726192dc141b586fa16db02b9c25 473 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site NPD12_1062 416b726192dc141b586fa16db02b9c25 473 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 12-10-2018 IPR018120 Glycoside hydrolase family 1, active site NPD12_1062 416b726192dc141b586fa16db02b9c25 473 SUPERFAMILY SSF51445 3 472 1.21E-158 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1062 416b726192dc141b586fa16db02b9c25 473 Pfam PF00232 Glycosyl hydrolase family 1 5 472 1.6E-135 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_3401 120b1b6dcab1b1fc68fb61958f4ec2be 99 PIRSF PIRSF012508 1 99 5.1E-47 T 12-10-2018 IPR013368 TrpR homologue YerC/YecD NPD12_3401 120b1b6dcab1b1fc68fb61958f4ec2be 99 Pfam PF01371 Trp repressor protein 12 95 1.8E-32 T 12-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 NPD12_3401 120b1b6dcab1b1fc68fb61958f4ec2be 99 Gene3D G3DSA:1.10.1270.10 2 99 6.6E-40 T 12-10-2018 IPR038116 TrpR-like superfamily NPD12_3401 120b1b6dcab1b1fc68fb61958f4ec2be 99 SUPERFAMILY SSF48295 2 96 4.55E-33 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 NPD12_3401 120b1b6dcab1b1fc68fb61958f4ec2be 99 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 10 96 4.1E-45 T 12-10-2018 IPR013368 TrpR homologue YerC/YecD NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Gene3D G3DSA:1.10.10.10 81 153 6.5E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Gene3D G3DSA:3.40.930.10 552 697 4.2E-53 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Gene3D G3DSA:3.40.50.2300 405 491 1.2E-15 T 12-10-2018 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 555 695 6.7E-34 T 12-10-2018 IPR002178 PTS EIIA type-2 domain NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 SUPERFAMILY SSF52794 405 491 4.45E-11 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 SUPERFAMILY SSF63520 296 398 6.8E-23 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Pfam PF08279 HTH domain 7 51 3.8E-6 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Pfam PF08279 HTH domain 94 151 8.1E-8 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Pfam PF00874 PRD domain 305 393 4.2E-22 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Pfam PF00874 PRD domain 197 282 2.0E-19 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 SUPERFAMILY SSF55804 552 696 4.32E-36 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Gene3D G3DSA:1.10.1790.10 188 286 3.1E-21 T 12-10-2018 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 407 483 2.3E-7 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 602 618 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Gene3D G3DSA:1.10.1790.10 299 396 4.9E-22 T 12-10-2018 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 SUPERFAMILY SSF63520 181 282 1.7E-21 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_2286 af53f4d412b65ffa109d96fdb84aabc5 697 Gene3D G3DSA:1.10.10.10 2 80 9.4E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3504 af374e03ae8fc0714ae353e0ee619fec 430 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 419 5.3E-120 T 12-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 NPD12_3504 af374e03ae8fc0714ae353e0ee619fec 430 Pfam PF02378 Phosphotransferase system, EIIC 29 349 5.2E-54 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_3504 af374e03ae8fc0714ae353e0ee619fec 430 PIRSF PIRSF006351 1 429 6.1E-134 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 3.0E-59 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 SUPERFAMILY SSF81338 3 234 2.75E-71 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 PRINTS PR00783 Major intrinsic protein family signature 136 154 4.2E-46 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 PRINTS PR00783 Major intrinsic protein family signature 166 188 4.2E-46 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 PRINTS PR00783 Major intrinsic protein family signature 81 100 4.2E-46 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 PRINTS PR00783 Major intrinsic protein family signature 44 68 4.2E-46 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 PRINTS PR00783 Major intrinsic protein family signature 213 233 4.2E-46 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 PRINTS PR00783 Major intrinsic protein family signature 2 21 4.2E-46 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 Pfam PF00230 Major intrinsic protein 4 230 3.9E-47 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 ProSitePatterns PS00221 MIP family signature. 62 70 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 NPD12_2818 5a8f4769bf9e8745297f8d172d35c198 234 Gene3D G3DSA:1.20.1080.10 1 234 8.9E-74 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 Pfam PF00771 FHIPEP family 25 677 6.5E-272 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 Gene3D G3DSA:1.10.8.540 496 584 9.4E-31 T 12-10-2018 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 231 245 3.3E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 69 88 3.3E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 180 197 3.3E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 150 168 3.3E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 131 147 3.3E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 32 45 3.3E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 Gene3D G3DSA:1.10.490.80 587 684 1.8E-23 T 12-10-2018 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 136 159 - T 12-10-2018 IPR025505 FHIPEP conserved site NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 PIRSF PIRSF005419 2 688 2.5E-257 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 15 685 6.7E-261 T 12-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 NPD12_2695 038a0c97c594fbb3153fb7f5f94de116 688 Gene3D G3DSA:3.40.30.60 353 495 2.9E-53 T 12-10-2018 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 207.633 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 SMART SM00788 3 424 9.6E-287 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 SUPERFAMILY SSF52540 1 426 2.55E-175 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 Gene3D G3DSA:3.40.440.10 5 260 2.2E-107 T 12-10-2018 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 5.5E-175 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 Gene3D G3DSA:3.90.170.10 267 428 3.6E-68 T 12-10-2018 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 Pfam PF00709 Adenylosuccinate synthetase 5 423 4.8E-187 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 NPD12_95 9e58b8bc0e19d1614aaacdbea2a73f8e 428 Gene3D G3DSA:1.10.300.10 102 201 2.2E-107 T 12-10-2018 NPD12_307 a56fbad225a01feec719b2a3b543b695 159 SUPERFAMILY SSF81573 65 122 1.1E-6 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily NPD12_307 a56fbad225a01feec719b2a3b543b695 159 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 139 12.631 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 NPD12_307 a56fbad225a01feec719b2a3b543b695 159 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 12 157 7.9E-29 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 NPD12_307 a56fbad225a01feec719b2a3b543b695 159 Pfam PF00430 ATP synthase B/B' CF(0) 8 137 8.3E-20 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 Gene3D G3DSA:1.10.390.10 422 571 5.2E-46 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily NPD12_1695 91798598966d3ad50bb872655f5ec859 579 SUPERFAMILY SSF55486 251 571 1.03E-78 T 12-10-2018 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 Gene3D G3DSA:3.10.170.10 255 421 8.8E-42 T 12-10-2018 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 256 417 5.1E-46 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 370 390 8.6E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 429 440 8.6E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 408 424 8.6E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 489 505 8.6E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 Pfam PF03413 Peptidase propeptide and YPEB domain 148 212 2.4E-8 T 12-10-2018 IPR025711 PepSY domain NPD12_1695 91798598966d3ad50bb872655f5ec859 579 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 420 571 2.2E-50 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 NPD12_1695 91798598966d3ad50bb872655f5ec859 579 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 1.7E-7 T 12-10-2018 IPR011096 FTP domain NPD12_3600 9aaee7fd3780e423baaaa49cd8f370b8 280 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 9 279 5.2E-100 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 NPD12_3600 9aaee7fd3780e423baaaa49cd8f370b8 280 Pfam PF05681 Fumarate hydratase (Fumerase) 11 277 3.7E-117 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 NPD12_2890 e14b06a41c6e5e5b1c952e700d4df343 405 Pfam PF00999 Sodium/hydrogen exchanger family 12 386 2.8E-70 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 NPD12_2890 e14b06a41c6e5e5b1c952e700d4df343 405 Gene3D G3DSA:1.20.1530.20 3 396 3.7E-97 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 SMART SM00304 327 379 8.7E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 SUPERFAMILY SSF103190 57 208 2.9E-8 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 Gene3D G3DSA:3.30.450.20 56 297 4.2E-56 T 12-10-2018 NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 SMART SM00283 394 683 3.0E-78 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 Gene3D G3DSA:1.10.287.950 375 683 2.8E-69 T 12-10-2018 NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 Gene3D G3DSA:3.30.450.20 64 199 4.2E-56 T 12-10-2018 NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 Pfam PF02743 Cache domain 38 289 4.7E-32 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 SUPERFAMILY SSF58104 347 683 6.28E-72 T 12-10-2018 NPD12_564 edadba61779d3677a547fbd11c5ed3b9 684 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 457 636 1.1E-44 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 ProSitePatterns PS00362 Ribosomal protein S15 signature. 37 67 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 Pfam PF00312 Ribosomal protein S15 6 86 1.0E-39 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 SUPERFAMILY SSF47060 2 87 9.71E-38 T 12-10-2018 IPR009068 S15/NS1, RNA-binding NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 3 87 2.4E-39 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 8 86 2.0E-33 T 12-10-2018 NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 Gene3D G3DSA:1.10.287.10 1 87 2.3E-36 T 12-10-2018 NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 87 23.123 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2461 78f51b9e1ef100ba5ff55bf98d902e27 87 SMART SM01387 6 86 1.3E-55 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_1002 9746bb6f81b14c5147ec390e155c932f 78 SUPERFAMILY SSF50037 8 76 1.95E-18 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal NPD12_1002 9746bb6f81b14c5147ec390e155c932f 78 SMART SM00899 5 77 1.1E-18 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1002 9746bb6f81b14c5147ec390e155c932f 78 Gene3D G3DSA:2.30.30.90 1 78 2.8E-22 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain NPD12_1002 9746bb6f81b14c5147ec390e155c932f 78 Pfam PF04023 FeoA domain 6 76 1.0E-14 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1044 2161a66f4015f193e106c0ca25983843 192 Gene3D G3DSA:3.40.50.450 1 191 1.2E-77 T 12-10-2018 NPD12_1044 2161a66f4015f193e106c0ca25983843 192 Pfam PF03641 Possible lysine decarboxylase 46 176 1.8E-42 T 12-10-2018 IPR031100 LOG family NPD12_1044 2161a66f4015f193e106c0ca25983843 192 SUPERFAMILY SSF102405 1 179 1.83E-58 T 12-10-2018 NPD12_1044 2161a66f4015f193e106c0ca25983843 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 5.3E-67 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 Gene3D G3DSA:3.40.630.10 13 461 5.5E-171 T 12-10-2018 NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 Pfam PF01546 Peptidase family M20/M25/M40 81 459 7.9E-36 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 112 151 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 Pfam PF07687 Peptidase dimerisation domain 257 365 1.5E-5 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 SUPERFAMILY SSF53187 3 462 3.14E-66 T 12-10-2018 NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 SUPERFAMILY SSF55031 182 376 1.45E-51 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 Gene3D G3DSA:3.30.70.360 182 377 5.5E-171 T 12-10-2018 NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 Gene3D G3DSA:3.30.70.360 201 288 5.5E-171 T 12-10-2018 NPD12_3484 d224e68804b61afb80c3e5ef5efce467 463 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 11 458 8.6E-166 T 12-10-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 NPD12_606 825749c252703408497e9ab0723226df 1279 Gene3D G3DSA:3.90.320.10 1044 1278 6.0E-77 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal NPD12_606 825749c252703408497e9ab0723226df 1279 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 450 1277 9.0E-265 T 12-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 NPD12_606 825749c252703408497e9ab0723226df 1279 SUPERFAMILY SSF52980 1067 1272 5.9E-38 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 NPD12_606 825749c252703408497e9ab0723226df 1279 Pfam PF13361 UvrD-like helicase C-terminal domain 491 936 1.2E-34 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 NPD12_606 825749c252703408497e9ab0723226df 1279 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1097 1263 3.1E-10 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type NPD12_606 825749c252703408497e9ab0723226df 1279 SUPERFAMILY SSF52540 4 941 1.73E-110 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_606 825749c252703408497e9ab0723226df 1279 Gene3D G3DSA:3.40.50.300 1 173 1.2E-37 T 12-10-2018 NPD12_606 825749c252703408497e9ab0723226df 1279 Gene3D G3DSA:3.40.50.300 285 492 1.1E-27 T 12-10-2018 NPD12_606 825749c252703408497e9ab0723226df 1279 Gene3D G3DSA:3.40.50.300 817 1016 6.8E-44 T 12-10-2018 NPD12_606 825749c252703408497e9ab0723226df 1279 Gene3D G3DSA:3.40.50.300 494 816 3.8E-50 T 12-10-2018 NPD12_606 825749c252703408497e9ab0723226df 1279 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 3 1278 19.485 T 12-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 NPD12_606 825749c252703408497e9ab0723226df 1279 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 479 9.7E-78 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 NPD12_790 13fef4fb674601fbb8ccb5b60e8b0d70 270 Gene3D G3DSA:3.40.50.2300 1 130 2.6E-26 T 12-10-2018 NPD12_790 13fef4fb674601fbb8ccb5b60e8b0d70 270 SMART SM00448 1 115 2.6E-10 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_790 13fef4fb674601fbb8ccb5b60e8b0d70 270 Pfam PF00072 Response regulator receiver domain 3 114 3.6E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_790 13fef4fb674601fbb8ccb5b60e8b0d70 270 Pfam PF08664 YcbB domain 146 264 4.4E-36 T 12-10-2018 IPR013972 YcbB domain NPD12_790 13fef4fb674601fbb8ccb5b60e8b0d70 270 SUPERFAMILY SSF52172 1 126 3.98E-25 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1400 9a4141e886b3e921ac0185fb4678e215 296 Pfam PF03313 Serine dehydratase alpha chain 15 276 1.1E-74 T 12-10-2018 IPR005130 Serine dehydratase-like, alpha subunit NPD12_1400 9a4141e886b3e921ac0185fb4678e215 296 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 3 292 5.4E-107 T 12-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 NPD12_1537 f9aa124bb9047df706fe08291ab4c5b0 157 SUPERFAMILY SSF53927 5 153 5.14E-41 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_1537 f9aa124bb9047df706fe08291ab4c5b0 157 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 1.2E-22 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain NPD12_1537 f9aa124bb9047df706fe08291ab4c5b0 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 NPD12_1537 f9aa124bb9047df706fe08291ab4c5b0 157 Gene3D G3DSA:3.40.140.10 1 157 2.0E-53 T 12-10-2018 NPD12_2839 8d4cc92ff1ea8df9fab03df13b4799dc 305 TIGRFAM TIGR03814 Gln_ase: glutaminase A 5 305 5.4E-128 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 NPD12_2839 8d4cc92ff1ea8df9fab03df13b4799dc 305 SUPERFAMILY SSF56601 4 305 3.16E-117 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_2839 8d4cc92ff1ea8df9fab03df13b4799dc 305 Pfam PF04960 Glutaminase 19 305 2.6E-122 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 NPD12_2839 8d4cc92ff1ea8df9fab03df13b4799dc 305 Hamap MF_00313 Glutaminase [glsA]. 1 305 48.21 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 NPD12_2839 8d4cc92ff1ea8df9fab03df13b4799dc 305 Gene3D G3DSA:3.40.710.10 1 305 4.9E-123 T 12-10-2018 NPD12_533 bba8f1e40884f0bc23eafcd7bcb6eff8 310 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 6 309 25.772 T 12-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 NPD12_533 bba8f1e40884f0bc23eafcd7bcb6eff8 310 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 11 307 4.5E-109 T 12-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 NPD12_533 bba8f1e40884f0bc23eafcd7bcb6eff8 310 Pfam PF03116 NQR2, RnfD, RnfE family 8 307 9.7E-125 T 12-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 NPD12_1197 5eb8202c2b208d25365e24bd7d6257f4 262 Gene3D G3DSA:3.40.50.620 1 261 2.4E-86 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1197 5eb8202c2b208d25365e24bd7d6257f4 262 Pfam PF01012 Electron transfer flavoprotein domain 22 207 2.0E-46 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_1197 5eb8202c2b208d25365e24bd7d6257f4 262 SMART SM00893 22 213 1.9E-59 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_1197 5eb8202c2b208d25365e24bd7d6257f4 262 SUPERFAMILY SSF52402 1 258 9.77E-76 T 12-10-2018 NPD12_1197 5eb8202c2b208d25365e24bd7d6257f4 262 PIRSF PIRSF000090 1 262 2.2E-85 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 NPD12_258 67dd9fd1e0b6634f06a03147ceb054bc 429 Pfam PF01969 Protein of unknown function DUF111 5 421 4.3E-156 T 12-10-2018 IPR002822 Nickel insertion protein NPD12_258 67dd9fd1e0b6634f06a03147ceb054bc 429 Hamap MF_01074 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein [larC]. 2 429 40.674 T 12-10-2018 IPR002822 Nickel insertion protein NPD12_258 67dd9fd1e0b6634f06a03147ceb054bc 429 Gene3D G3DSA:3.10.20.300 372 429 4.4E-7 T 12-10-2018 NPD12_258 67dd9fd1e0b6634f06a03147ceb054bc 429 Gene3D G3DSA:3.30.70.1380 281 371 3.2E-18 T 12-10-2018 NPD12_258 67dd9fd1e0b6634f06a03147ceb054bc 429 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 4 421 3.4E-112 T 12-10-2018 IPR002822 Nickel insertion protein NPD12_492 823edb3f68c9ec30be75ad0158bceb2a 502 Gene3D G3DSA:1.20.1570.10 206 334 9.3E-166 T 12-10-2018 NPD12_492 823edb3f68c9ec30be75ad0158bceb2a 502 Gene3D G3DSA:3.40.140.40 348 494 2.2E-53 T 12-10-2018 NPD12_492 823edb3f68c9ec30be75ad0158bceb2a 502 PIRSF PIRSF033132 1 502 5.4E-269 T 12-10-2018 IPR014999 Uncharacterised protein family UPF0371 NPD12_492 823edb3f68c9ec30be75ad0158bceb2a 502 Gene3D G3DSA:3.10.630.10 3 284 9.3E-166 T 12-10-2018 NPD12_492 823edb3f68c9ec30be75ad0158bceb2a 502 Hamap MF_01567 UPF0371 protein . 1 502 59.77 T 12-10-2018 IPR014999 Uncharacterised protein family UPF0371 NPD12_492 823edb3f68c9ec30be75ad0158bceb2a 502 Pfam PF08903 Domain of unknown function (DUF1846) 3 499 7.9E-239 T 12-10-2018 IPR014999 Uncharacterised protein family UPF0371 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 Pfam PF00122 E1-E2 ATPase 119 289 9.5E-49 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 Gene3D G3DSA:3.40.1110.10 321 443 5.3E-85 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 SUPERFAMILY SSF81665 74 591 8.63E-13 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 591 3.4E-79 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 69 613 8.0E-172 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 468 6.3E-27 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 310 324 6.3E-27 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 530 6.3E-27 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 6.3E-27 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 547 6.3E-27 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 Gene3D G3DSA:2.70.150.20 112 222 3.7E-36 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 SUPERFAMILY SSF56784 309 611 9.9E-49 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 Pfam PF00702 haloacid dehalogenase-like hydrolase 307 524 1.5E-34 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 312 318 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 65 614 4.4E-129 T 12-10-2018 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 Gene3D G3DSA:3.40.50.1000 291 563 5.3E-85 T 12-10-2018 IPR023214 HAD superfamily NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 543 568 2.8E-5 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 511 527 2.8E-5 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2238 43bb9482c445518b8b2ca1327b64884e 623 SUPERFAMILY SSF81653 121 218 5.23E-26 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 SMART SM00388 124 190 2.3E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 SUPERFAMILY SSF55874 180 342 2.62E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 SUPERFAMILY SSF47384 107 191 2.16E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 Pfam PF00672 HAMP domain 72 118 5.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 Gene3D G3DSA:1.10.287.130 124 188 4.9E-19 T 12-10-2018 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 Gene3D G3DSA:1.20.1480.50 40 123 9.4E-11 T 12-10-2018 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 341 8.6E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 SUPERFAMILY SSF158472 72 120 1.31E-9 T 12-10-2018 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 Pfam PF00512 His Kinase A (phospho-acceptor) domain 125 189 1.1E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 Gene3D G3DSA:3.30.565.10 189 342 2.8E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 SMART SM00387 234 342 1.3E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 3.4E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 3.4E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 3.4E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 3.4E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1088 2ca8fffbd65a3cd9888f680729921d31 342 SMART SM00304 70 123 8.3E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.9E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.4E-221 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 SUPERFAMILY SSF50447 207 304 2.75E-29 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 Gene3D G3DSA:3.40.50.300 1 205 2.4E-72 T 12-10-2018 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 SUPERFAMILY SSF50465 305 396 1.81E-34 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 Gene3D G3DSA:2.40.30.10 341 395 2.4E-27 T 12-10-2018 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 Gene3D G3DSA:2.40.30.10 208 337 1.8E-52 T 12-10-2018 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.9E-60 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 SUPERFAMILY SSF52540 4 216 2.36E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.3E-31 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 60.003 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_3641 8ded8c8d9980985f6d6f32c2f162b99e 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.5E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.9E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.4E-221 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 SUPERFAMILY SSF50447 207 304 2.75E-29 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 Gene3D G3DSA:3.40.50.300 1 205 2.4E-72 T 12-10-2018 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 SUPERFAMILY SSF50465 305 396 1.81E-34 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 Gene3D G3DSA:2.40.30.10 341 395 2.4E-27 T 12-10-2018 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 Gene3D G3DSA:2.40.30.10 208 337 1.8E-52 T 12-10-2018 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.9E-60 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 SUPERFAMILY SSF52540 4 216 2.36E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.3E-31 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.6E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 60.003 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_3655 8ded8c8d9980985f6d6f32c2f162b99e 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.5E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_2131 5ad4098989ee6508597e8a20b37c1a92 221 Pfam PF00072 Response regulator receiver domain 5 114 3.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2131 5ad4098989ee6508597e8a20b37c1a92 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 219 2.0E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2131 5ad4098989ee6508597e8a20b37c1a92 221 SMART SM00862 148 219 1.7E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2131 5ad4098989ee6508597e8a20b37c1a92 221 Gene3D G3DSA:3.40.50.2300 2 131 7.3E-38 T 12-10-2018 NPD12_2131 5ad4098989ee6508597e8a20b37c1a92 221 Gene3D G3DSA:1.10.10.10 132 221 3.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2131 5ad4098989ee6508597e8a20b37c1a92 221 SUPERFAMILY SSF52172 3 175 3.62E-40 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2131 5ad4098989ee6508597e8a20b37c1a92 221 SMART SM00448 3 113 2.4E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_418 e2f45d25aa75c0cad2ef4f428155740e 309 SMART SM00479 2 166 3.7E-12 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_418 e2f45d25aa75c0cad2ef4f428155740e 309 Gene3D G3DSA:3.30.420.10 1 170 3.0E-35 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_418 e2f45d25aa75c0cad2ef4f428155740e 309 SUPERFAMILY SSF52113 217 306 9.53E-10 T 12-10-2018 IPR036420 BRCT domain superfamily NPD12_418 e2f45d25aa75c0cad2ef4f428155740e 309 SUPERFAMILY SSF53098 1 170 2.35E-39 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_418 e2f45d25aa75c0cad2ef4f428155740e 309 Pfam PF00929 Exonuclease 4 156 8.3E-22 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_418 e2f45d25aa75c0cad2ef4f428155740e 309 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 217 290 1.5E-7 T 12-10-2018 IPR001357 BRCT domain NPD12_418 e2f45d25aa75c0cad2ef4f428155740e 309 Gene3D G3DSA:3.40.50.10190 195 307 4.1E-18 T 12-10-2018 IPR036420 BRCT domain superfamily NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Pfam PF06480 FtsH Extracellular 18 104 6.8E-9 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 13 617 35.077 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 114 601 1.8E-208 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 SMART SM00382 197 335 6.2E-25 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Gene3D G3DSA:1.20.58.760 414 621 2.1E-72 T 12-10-2018 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 SUPERFAMILY SSF52540 162 416 1.83E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Gene3D G3DSA:2.40.50.920 34 114 1.3E-6 T 12-10-2018 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Gene3D G3DSA:3.40.50.300 149 334 9.0E-69 T 12-10-2018 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Gene3D G3DSA:1.10.8.60 335 411 4.7E-25 T 12-10-2018 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 332 1.4E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 SUPERFAMILY SSF140990 414 605 1.23E-70 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 NPD12_3483 189c7ad882da7b59ef54a04013a462b8 658 Pfam PF01434 Peptidase family M41 394 600 6.9E-72 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 NPD12_1612 af15676dbb11d3d8d13b5bb7c581db27 451 Pfam PF02378 Phosphotransferase system, EIIC 121 392 4.7E-32 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_1612 af15676dbb11d3d8d13b5bb7c581db27 451 SUPERFAMILY SSF55604 7 83 1.1E-20 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1612 af15676dbb11d3d8d13b5bb7c581db27 451 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_1612 af15676dbb11d3d8d13b5bb7c581db27 451 Gene3D G3DSA:3.30.1360.60 1 79 3.4E-26 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1612 af15676dbb11d3d8d13b5bb7c581db27 451 Pfam PF00367 phosphotransferase system, EIIB 9 39 1.7E-14 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 Pfam PF01476 LysM domain 35 79 2.3E-12 T 12-10-2018 IPR018392 LysM domain NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 Pfam PF00188 Cysteine-rich secretory protein family 93 208 3.7E-16 T 12-10-2018 IPR014044 CAP domain NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 Gene3D G3DSA:3.40.33.10 80 211 2.7E-39 T 12-10-2018 IPR035940 CAP superfamily NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 SMART SM00257 34 79 7.4E-14 T 12-10-2018 IPR018392 LysM domain NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 Gene3D G3DSA:3.10.350.10 33 78 3.5E-13 T 12-10-2018 IPR036779 LysM domain superfamily NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 SUPERFAMILY SSF54106 33 79 3.79E-9 T 12-10-2018 NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 37 79 2.6E-20 T 12-10-2018 IPR014248 Spore coat assembly protein SafA NPD12_1924 ead7ef8b929944a601f83d7cc468d751 211 SUPERFAMILY SSF55797 85 209 2.09E-22 T 12-10-2018 IPR035940 CAP superfamily NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 SUPERFAMILY SSF51735 3 248 2.22E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 5.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 5.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 5.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 Pfam PF00106 short chain dehydrogenase 3 192 2.6E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 Gene3D G3DSA:3.40.50.720 4 260 1.9E-50 T 12-10-2018 NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_2359 f9b36e51171aa8afcbeb15f6e6ae8cf4 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1203 27db1bdb0c1c611132f44850975e1fa4 181 Pfam PF04199 Putative cyclase 21 125 3.9E-10 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_1203 27db1bdb0c1c611132f44850975e1fa4 181 Gene3D G3DSA:3.50.30.50 19 173 3.0E-17 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_1203 27db1bdb0c1c611132f44850975e1fa4 181 SUPERFAMILY SSF102198 26 158 2.35E-22 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 SMART SM00382 363 549 3.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 Gene3D G3DSA:1.20.1560.10 5 321 5.4E-30 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 Gene3D G3DSA:3.40.50.300 329 580 1.9E-89 T 12-10-2018 NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 Pfam PF00005 ABC transporter 354 503 2.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 SUPERFAMILY SSF90123 6 319 9.29E-41 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 Pfam PF00664 ABC transporter transmembrane region 40 294 3.3E-11 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 SUPERFAMILY SSF52540 331 571 2.55E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2401 f4369e77c3ebad9b38250b307aefb64e 581 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1140 bf489552784270f0ecafb6d854af55c8 173 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 2 172 7.0E-52 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 NPD12_1140 bf489552784270f0ecafb6d854af55c8 173 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 4 172 3.8E-62 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 NPD12_1140 bf489552784270f0ecafb6d854af55c8 173 PIRSF PIRSF015617 1 173 1.4E-63 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 NPD12_1140 bf489552784270f0ecafb6d854af55c8 173 SUPERFAMILY SSF52540 2 172 6.43E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1140 bf489552784270f0ecafb6d854af55c8 173 Gene3D G3DSA:3.40.50.300 1 172 9.2E-62 T 12-10-2018 NPD12_1372 dbc823ac89ffd5cca05f8b1f32ec5f9c 356 Pfam PF03054 tRNA methyl transferase 3 354 4.2E-125 T 12-10-2018 NPD12_1372 dbc823ac89ffd5cca05f8b1f32ec5f9c 356 Gene3D G3DSA:3.40.50.620 1 212 6.2E-85 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1372 dbc823ac89ffd5cca05f8b1f32ec5f9c 356 Gene3D G3DSA:2.40.30.10 276 356 1.6E-26 T 12-10-2018 NPD12_1372 dbc823ac89ffd5cca05f8b1f32ec5f9c 356 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 3 355 41.102 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 NPD12_1372 dbc823ac89ffd5cca05f8b1f32ec5f9c 356 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 3 354 6.5E-114 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 NPD12_1372 dbc823ac89ffd5cca05f8b1f32ec5f9c 356 Gene3D G3DSA:2.30.30.280 217 275 1.5E-16 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 NPD12_1372 dbc823ac89ffd5cca05f8b1f32ec5f9c 356 SUPERFAMILY SSF52402 2 246 1.68E-59 T 12-10-2018 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.511 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 Gene3D G3DSA:3.90.930.12 84 179 4.5E-40 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 Gene3D G3DSA:3.90.930.12 1 83 6.3E-30 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 SUPERFAMILY SSF56053 84 178 3.45E-36 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 SUPERFAMILY SSF56053 1 83 1.99E-25 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 PIRSF PIRSF002162 1 178 2.0E-46 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 2.1E-75 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.0E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.0E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.0E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 Pfam PF00347 Ribosomal protein L6 11 83 1.7E-18 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3624 dab0fd8bb794ca5ba961b6135a9b2d85 180 Pfam PF00347 Ribosomal protein L6 91 165 2.7E-20 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 2.0E-16 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 27.66 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 Gene3D G3DSA:2.40.50.100 28 93 5.2E-27 T 12-10-2018 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 PRINTS PR00063 Ribosomal protein L27 signature 62 86 2.5E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 PRINTS PR00063 Ribosomal protein L27 signature 12 36 2.5E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 PRINTS PR00063 Ribosomal protein L27 signature 37 61 2.5E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 SUPERFAMILY SSF110324 10 91 1.12E-33 T 12-10-2018 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 Pfam PF01016 Ribosomal L27 protein 10 87 2.2E-36 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3093 868811a9dfb16df491da0bdccbb31ba2 100 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 90 1.8E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_1306 79d051fface8442e6c3c5bfafc2d1caa 111 Pfam PF00085 Thioredoxin 8 84 2.2E-8 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 NPD12_1306 79d051fface8442e6c3c5bfafc2d1caa 111 Gene3D G3DSA:3.40.30.10 1 104 4.0E-20 T 12-10-2018 NPD12_1306 79d051fface8442e6c3c5bfafc2d1caa 111 SUPERFAMILY SSF52833 2 109 1.88E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_2536 fe14da791e8fdc8d2317ea5b0bab983e 436 TIGRFAM TIGR04481 PR_assoc_PrdC: proline reductase-associated electron transfer protein PrdC 5 429 3.5E-198 T 12-10-2018 IPR031001 Proline reductase-associated electron transfer protein PrdC NPD12_2536 fe14da791e8fdc8d2317ea5b0bab983e 436 Gene3D G3DSA:3.40.50.11540 89 235 2.3E-19 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2536 fe14da791e8fdc8d2317ea5b0bab983e 436 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 84 227 1.7E-44 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2536 fe14da791e8fdc8d2317ea5b0bab983e 436 SUPERFAMILY SSF142019 64 245 1.57E-50 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2536 fe14da791e8fdc8d2317ea5b0bab983e 436 Pfam PF13375 RnfC Barrel sandwich hybrid domain 7 57 5.2E-13 T 12-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 Pfam PF00344 SecY translocase 69 408 4.5E-109 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PIRSF PIRSF004557 1 425 5.0E-119 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 SUPERFAMILY SSF103491 1 415 8.89E-119 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 Gene3D G3DSA:1.10.3370.10 1 420 1.9E-157 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 419 1.3E-115 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 ProSitePatterns PS00756 Protein secY signature 2. 162 179 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 360 378 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 143 168 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 261 280 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 393 411 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 305 327 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 PRINTS PR00303 Preprotein translocase SecY subunit signature 169 192 1.6E-83 T 12-10-2018 NPD12_3619 803beb419a7ebdb62adeef407b43050d 425 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 424 28.723 T 12-10-2018 IPR026593 Protein translocase subunit SecY NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 SMART SM00363 15 74 1.3E-5 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 Pfam PF01479 S4 domain 15 61 9.0E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 SUPERFAMILY SSF55174 14 101 3.36E-10 T 12-10-2018 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 300 1.6E-100 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 Gene3D G3DSA:3.10.290.10 3 69 6.1E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 SUPERFAMILY SSF55120 74 301 3.08E-81 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 Pfam PF00849 RNA pseudouridylate synthase 88 242 1.1E-37 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1726 02745d644be65b220fc5d73e14904ee2 305 Gene3D G3DSA:3.30.2350.10 81 304 3.8E-79 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 6 1144 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Pfam PF02436 Conserved carboxylase domain 823 1022 1.7E-75 T 12-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 SUPERFAMILY SSF89000 828 1004 7.45E-59 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Gene3D G3DSA:3.20.20.70 508 812 9.2E-274 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 113 1.7E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Gene3D G3DSA:1.10.472.90 813 937 9.2E-274 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 PIRSF PIRSF001594 1 1144 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 SUPERFAMILY SSF51246 340 458 1.36E-36 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Pfam PF00682 HMGL-like 529 801 3.3E-32 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Pfam PF00364 Biotin-requiring enzyme 1078 1143 1.1E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 SUPERFAMILY SSF51569 520 831 4.76E-79 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 289 296 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Gene3D G3DSA:2.40.50.100 1068 1144 2.7E-24 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Pfam PF02785 Biotin carboxylase C-terminal domain 345 453 8.1E-32 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Gene3D G3DSA:3.10.600.10 505 1055 9.2E-274 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 SUPERFAMILY SSF52440 3 116 6.4E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 325 3.2E-78 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 SUPERFAMILY SSF56059 86 331 2.47E-68 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1100 1117 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 SMART SM00878 345 452 1.4E-50 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Gene3D G3DSA:3.30.470.130 1 460 2.0E-199 T 12-10-2018 NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 SUPERFAMILY SSF51230 1067 1144 5.76E-22 T 12-10-2018 IPR011053 Single hybrid motif NPD12_3440 2bdda3d7e92bfddc800198f830b06524 1144 Gene3D G3DSA:1.10.10.2790 938 973 9.2E-274 T 12-10-2018 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 Gene3D G3DSA:3.30.565.10 349 503 2.4E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_530 7ace448ee36c39e8731359887c6a8916 504 SMART SM00387 391 502 1.3E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_530 7ace448ee36c39e8731359887c6a8916 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 496 7.2E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_530 7ace448ee36c39e8731359887c6a8916 504 SUPERFAMILY SSF158472 224 268 4.18E-6 T 12-10-2018 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 SMART SM00304 218 270 9.8E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 Pfam PF00512 His Kinase A (phospho-acceptor) domain 278 340 2.6E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 Gene3D G3DSA:1.10.287.130 273 348 4.8E-19 T 12-10-2018 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 SUPERFAMILY SSF55874 335 498 3.27E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_530 7ace448ee36c39e8731359887c6a8916 504 Gene3D G3DSA:1.20.1480.50 188 272 5.9E-7 T 12-10-2018 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 4.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 4.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 SMART SM00388 278 345 1.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_530 7ace448ee36c39e8731359887c6a8916 504 SUPERFAMILY SSF47384 261 345 2.94E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 SUPERFAMILY SSF53920 39 326 4.05E-62 T 12-10-2018 IPR009016 Iron hydrogenase NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 423 522 2.4E-7 T 12-10-2018 IPR000014 PAS domain NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 SUPERFAMILY SSF54862 5 80 1.59E-18 T 12-10-2018 NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 Gene3D G3DSA:1.10.15.40 367 421 2.5E-5 T 12-10-2018 NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 Gene3D G3DSA:3.40.950.20 109 320 7.7E-24 T 12-10-2018 NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 Pfam PF04060 Putative Fe-S cluster 381 409 4.9E-7 T 12-10-2018 IPR007202 4Fe-4S domain GO:0051536 NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 Pfam PF12838 4Fe-4S dicluster domain 11 54 9.3E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 72 299 3.0E-51 T 12-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 SMART SM00091 418 484 0.0066 T 12-10-2018 IPR000014 PAS domain NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 Gene3D G3DSA:3.30.450.20 422 518 2.0E-8 T 12-10-2018 NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 Gene3D G3DSA:3.30.70.20 3 78 1.6E-12 T 12-10-2018 NPD12_1982 fe7f137a02ce602d85f55ee44b65fda6 579 SUPERFAMILY SSF55785 423 518 7.23E-6 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_1729 2180a2b263d621b879631e1852ddb940 253 SUPERFAMILY SSF56219 1 253 4.06E-84 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily NPD12_1729 2180a2b263d621b879631e1852ddb940 253 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 9.2E-101 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 NPD12_1729 2180a2b263d621b879631e1852ddb940 253 Gene3D G3DSA:3.60.10.10 1 253 1.3E-98 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily NPD12_1729 2180a2b263d621b879631e1852ddb940 253 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 252 8.5E-97 T 12-10-2018 NPD12_1729 2180a2b263d621b879631e1852ddb940 253 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 12-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 NPD12_1729 2180a2b263d621b879631e1852ddb940 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 245 6.0E-21 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase NPD12_1751 1c61e1ed79c2f724a174efda03c84bee 340 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 16 336 52.077 T 12-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 NPD12_1751 1c61e1ed79c2f724a174efda03c84bee 340 SUPERFAMILY SSF55681 20 333 1.53E-100 T 12-10-2018 NPD12_1751 1c61e1ed79c2f724a174efda03c84bee 340 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 26 333 3.4E-122 T 12-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 NPD12_1751 1c61e1ed79c2f724a174efda03c84bee 340 Gene3D G3DSA:3.30.930.10 18 336 1.1E-151 T 12-10-2018 NPD12_1751 1c61e1ed79c2f724a174efda03c84bee 340 PIRSF PIRSF001555 12 340 3.8E-167 T 12-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 NPD12_1751 1c61e1ed79c2f724a174efda03c84bee 340 Pfam PF03590 Aspartate-ammonia ligase 25 250 4.6E-113 T 12-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 NPD12_2303 231dc9366d4ed89e2ab904d6d96756b4 487 Gene3D G3DSA:3.40.50.1820 112 471 4.2E-81 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2303 231dc9366d4ed89e2ab904d6d96756b4 487 SUPERFAMILY SSF53474 143 464 3.46E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2303 231dc9366d4ed89e2ab904d6d96756b4 487 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 116 447 1.4E-21 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 NPD12_1142 ed0c3a3a5c55559030b629feae741fee 254 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 12-10-2018 IPR024002 Formate/nitrite transporter, conserved site NPD12_1142 ed0c3a3a5c55559030b629feae741fee 254 Gene3D G3DSA:1.20.1080.10 1 254 1.2E-85 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 NPD12_1142 ed0c3a3a5c55559030b629feae741fee 254 Pfam PF01226 Formate/nitrite transporter 10 249 6.7E-68 T 12-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 NPD12_1142 ed0c3a3a5c55559030b629feae741fee 254 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 159 169 - T 12-10-2018 IPR024002 Formate/nitrite transporter, conserved site NPD12_1669 45a949942de893be85dca2ae505e4511 424 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 257 2.5E-48 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 NPD12_1669 45a949942de893be85dca2ae505e4511 424 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 3.1E-8 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_1669 45a949942de893be85dca2ae505e4511 424 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 63 74 3.1E-8 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_1669 45a949942de893be85dca2ae505e4511 424 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 3.1E-8 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_1669 45a949942de893be85dca2ae505e4511 424 SUPERFAMILY SSF56601 8 279 5.63E-58 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_1669 45a949942de893be85dca2ae505e4511 424 Gene3D G3DSA:3.40.710.10 16 303 2.0E-80 T 12-10-2018 NPD12_51 a9d4941c96aa3ccf36b459e510afc341 458 SUPERFAMILY SSF102114 34 339 1.44E-44 T 12-10-2018 NPD12_51 a9d4941c96aa3ccf36b459e510afc341 458 Gene3D G3DSA:3.20.20.70 6 380 7.2E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_51 a9d4941c96aa3ccf36b459e510afc341 458 Pfam PF04055 Radical SAM superfamily 80 228 1.7E-8 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_51 a9d4941c96aa3ccf36b459e510afc341 458 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 2 457 1.0E-194 T 12-10-2018 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM NPD12_51 a9d4941c96aa3ccf36b459e510afc341 458 SMART SM00876 262 369 3.5E-31 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_51 a9d4941c96aa3ccf36b459e510afc341 458 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 262 366 9.2E-22 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 NPD12_2918 8b0d8b23305c5b09f6361063d1b75dae 154 Gene3D G3DSA:3.40.50.960 1 154 1.6E-66 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2918 8b0d8b23305c5b09f6361063d1b75dae 154 SUPERFAMILY SSF52121 3 153 2.09E-64 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2918 8b0d8b23305c5b09f6361063d1b75dae 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 31.952 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2918 8b0d8b23305c5b09f6361063d1b75dae 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 6.3E-61 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2918 8b0d8b23305c5b09f6361063d1b75dae 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 151 7.5E-63 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2571 780f84e8ec8f9e87fddc3e0abc9e586d 294 SUPERFAMILY SSF161098 10 281 4.3E-37 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2571 780f84e8ec8f9e87fddc3e0abc9e586d 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 287 1.8E-32 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_2571 780f84e8ec8f9e87fddc3e0abc9e586d 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 7 287 2.0E-81 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 NPD12_2571 780f84e8ec8f9e87fddc3e0abc9e586d 294 Gene3D G3DSA:1.10.3720.10 55 289 6.5E-32 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 SUPERFAMILY SSF48150 114 296 8.55E-37 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 Gene3D G3DSA:3.30.310.260 1 113 7.9E-42 T 12-10-2018 NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 16 118 2.3E-23 T 12-10-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 SUPERFAMILY SSF55945 12 113 2.51E-22 T 12-10-2018 NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 Gene3D G3DSA:1.10.340.30 114 244 1.4E-34 T 12-10-2018 NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 SMART SM00478 124 296 1.4E-9 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 120 271 2.3E-15 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 NPD12_3431 5df1b4d762ab62b219d1cca748c339cc 305 Gene3D G3DSA:1.10.1670.50 245 302 7.2E-27 T 12-10-2018 NPD12_2655 0b07136216341717eff6a6387c5575f0 62 Gene3D G3DSA:1.10.287.540 3 56 5.2E-21 T 12-10-2018 NPD12_2655 0b07136216341717eff6a6387c5575f0 62 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 53 1.1E-18 T 12-10-2018 IPR009242 Protein of unknown function DUF896 NPD12_2655 0b07136216341717eff6a6387c5575f0 62 Hamap MF_01103 UPF0291 protein . 1 61 14.52 T 12-10-2018 IPR009242 Protein of unknown function DUF896 NPD12_2655 0b07136216341717eff6a6387c5575f0 62 SUPERFAMILY SSF158221 1 42 9.94E-15 T 12-10-2018 NPD12_3362 0309dddc4389fb174c105f16ec441c36 188 SUPERFAMILY SSF160387 110 188 2.17E-20 T 12-10-2018 NPD12_3362 0309dddc4389fb174c105f16ec441c36 188 Pfam PF03243 Alkylmercury lyase 106 187 1.4E-14 T 12-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 NPD12_3362 0309dddc4389fb174c105f16ec441c36 188 Gene3D G3DSA:2.40.10.490 20 188 1.7E-32 T 12-10-2018 NPD12_1593 b67d845f09029fbae2c244765b898398 147 Pfam PF13247 4Fe-4S dicluster domain 57 145 7.3E-21 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1593 b67d845f09029fbae2c244765b898398 147 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 94 105 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1593 b67d845f09029fbae2c244765b898398 147 Gene3D G3DSA:3.30.70.20 2 147 1.0E-26 T 12-10-2018 NPD12_1593 b67d845f09029fbae2c244765b898398 147 SUPERFAMILY SSF54862 4 143 2.51E-35 T 12-10-2018 NPD12_639 8ed892d20be4c21f975e03f47f8654eb 1180 SUPERFAMILY SSF52540 1 1154 1.8E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_639 8ed892d20be4c21f975e03f47f8654eb 1180 Pfam PF13476 AAA domain 5 263 2.5E-23 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain NPD12_639 8ed892d20be4c21f975e03f47f8654eb 1180 Gene3D G3DSA:3.40.50.300 1 302 1.5E-43 T 12-10-2018 NPD12_639 8ed892d20be4c21f975e03f47f8654eb 1180 Gene3D G3DSA:3.40.50.300 943 1179 1.6E-27 T 12-10-2018 NPD12_639 8ed892d20be4c21f975e03f47f8654eb 1180 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1064 1135 4.9E-14 T 12-10-2018 NPD12_639 8ed892d20be4c21f975e03f47f8654eb 1180 SUPERFAMILY SSF52540 1 281 1.4E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 Pfam PF07501 G5 domain 156 229 2.3E-19 T 12-10-2018 IPR011098 G5 domain NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 SUPERFAMILY SSF50685 290 339 8.02E-10 T 12-10-2018 IPR036908 RlpA-like domain superfamily NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 Pfam PF03990 Domain of unknown function (DUF348) 99 138 2.2E-10 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 Pfam PF03990 Domain of unknown function (DUF348) 43 82 6.9E-9 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 Gene3D G3DSA:2.20.230.10 131 232 9.2E-18 T 12-10-2018 NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 Gene3D G3DSA:2.40.40.10 265 336 9.2E-7 T 12-10-2018 IPR036908 RlpA-like domain superfamily NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 SMART SM01208 152 230 1.6E-24 T 12-10-2018 IPR011098 G5 domain NPD12_235 3b2ced2a6e1515d41b50af8550c7423a 352 Pfam PF06725 3D domain 291 351 4.2E-22 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 NPD12_557 68a307933eda6d1f3ed5beacf48e045d 231 Pfam PF01863 Protein of unknown function DUF45 21 225 1.2E-57 T 12-10-2018 IPR002725 Protein of unknown function DUF45 NPD12_557 68a307933eda6d1f3ed5beacf48e045d 231 Gene3D G3DSA:3.30.2010.10 132 224 1.7E-20 T 12-10-2018 NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 6 88 4.4E-30 T 12-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 167 200 6.8E-11 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 Gene3D G3DSA:3.30.70.250 3 85 1.1E-29 T 12-10-2018 NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 120 1.0E-4 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 123 157 5.2E-6 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 175 203 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 Gene3D G3DSA:2.160.10.10 86 236 2.8E-46 T 12-10-2018 NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 SUPERFAMILY SSF51161 89 225 1.2E-49 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 3 236 43.19 T 12-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 NPD12_3268 90275ce421eee6be749d0a547ccc8e81 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 9 236 1.0E-118 T 12-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 417 433 6.2E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 504 520 6.2E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 379 399 6.2E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 438 449 6.2E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 SUPERFAMILY SSF55486 261 586 6.23E-75 T 12-10-2018 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 1.0E-7 T 12-10-2018 IPR011096 FTP domain NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 263 426 8.7E-45 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 Gene3D G3DSA:3.10.170.10 262 430 4.8E-41 T 12-10-2018 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 Pfam PF03413 Peptidase propeptide and YPEB domain 148 212 4.3E-8 T 12-10-2018 IPR025711 PepSY domain NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 429 586 2.5E-49 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 NPD12_1694 9cb5dbcc780b00b24492bfb356c80e67 594 Gene3D G3DSA:1.10.390.10 431 586 4.3E-46 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily NPD12_3523 449adfc0e4eb7def8e32e98b8e84a5e8 135 Gene3D G3DSA:3.40.630.30 1 120 3.0E-20 T 12-10-2018 NPD12_3523 449adfc0e4eb7def8e32e98b8e84a5e8 135 SUPERFAMILY SSF55729 2 134 1.33E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_3523 449adfc0e4eb7def8e32e98b8e84a5e8 135 Pfam PF00583 Acetyltransferase (GNAT) family 11 112 1.4E-14 T 12-10-2018 IPR000182 GNAT domain NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 SUPERFAMILY SSF82282 2 355 2.62E-107 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 SUPERFAMILY SSF52242 666 789 7.59E-42 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 SUPERFAMILY SSF47644 587 663 1.09E-13 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Pfam PF02607 B12 binding domain 588 656 2.4E-13 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Gene3D G3DSA:1.10.1240.10 575 664 2.1E-15 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 PIRSF PIRSF037472 1 791 0.0 T 12-10-2018 IPR017215 5-methyltetrahydrofolate-homocysteine S-methyltransferase, bacterial NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Pfam PF02310 B12 binding domain 672 778 1.3E-22 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 SUPERFAMILY SSF51717 314 570 6.02E-85 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Gene3D G3DSA:3.20.20.330 1 297 4.2E-92 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Pfam PF02574 Homocysteine S-methyltransferase 12 281 7.4E-59 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Gene3D G3DSA:3.20.20.20 312 574 2.0E-97 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Pfam PF00809 Pterin binding enzyme 316 536 1.2E-35 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 Gene3D G3DSA:3.40.50.280 669 791 1.1E-45 T 12-10-2018 NPD12_1863 bbab8c0e271a64bd55218784d383155f 792 SMART SM01018 582 664 2.0E-25 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Gene3D G3DSA:3.30.360.90 364 436 1.1E-26 T 12-10-2018 NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 95 180 1.1E-13 T 12-10-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Pfam PF17482 Phage tail sheath C-terminal domain 335 435 1.5E-24 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Gene3D G3DSA:3.40.50.11790 188 354 5.5E-58 T 12-10-2018 NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 181 328 2.9E-33 T 12-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Gene3D G3DSA:1.10.10.2290 248 326 5.5E-58 T 12-10-2018 NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Gene3D G3DSA:3.30.1490.360 25 92 1.3E-25 T 12-10-2018 NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 311 436 1.0E-22 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain NPD12_1497 e30db0bdadbc0c229a7b690ef1b06173 436 Gene3D G3DSA:3.30.160.610 93 182 2.1E-29 T 12-10-2018 NPD12_2758 fe00e3d00da4e1ea14a506ef8e05328a 343 SMART SM00858 276 334 3.5E-11 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 NPD12_2758 fe00e3d00da4e1ea14a506ef8e05328a 343 Pfam PF03102 NeuB family 37 265 8.1E-76 T 12-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 NPD12_2758 fe00e3d00da4e1ea14a506ef8e05328a 343 Gene3D G3DSA:3.20.20.70 1 281 4.4E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2758 fe00e3d00da4e1ea14a506ef8e05328a 343 Pfam PF08666 SAF domain 277 330 2.0E-7 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 NPD12_2758 fe00e3d00da4e1ea14a506ef8e05328a 343 Gene3D G3DSA:3.90.1210.10 282 336 6.2E-13 T 12-10-2018 NPD12_2758 fe00e3d00da4e1ea14a506ef8e05328a 343 SUPERFAMILY SSF51269 274 333 1.16E-14 T 12-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 NPD12_2758 fe00e3d00da4e1ea14a506ef8e05328a 343 SUPERFAMILY SSF51569 3 286 1.34E-84 T 12-10-2018 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 Gene3D G3DSA:3.30.2350.10 79 313 4.9E-48 T 12-10-2018 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 SUPERFAMILY SSF55174 11 59 1.31E-5 T 12-10-2018 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 Pfam PF01479 S4 domain 12 58 1.6E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 SMART SM00363 12 95 0.0016 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 Gene3D G3DSA:3.10.290.10 1 64 2.7E-13 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 8 295 2.6E-59 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 Pfam PF00849 RNA pseudouridylate synthase 87 246 4.5E-27 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 SUPERFAMILY SSF55120 73 292 3.08E-47 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1684 ffc86c8524eb6dc06182b5a42f6df0f8 317 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 137 151 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_712 bd5b4808f6346a22370f19f815f11430 638 SUPERFAMILY SSF52402 316 618 2.01E-74 T 12-10-2018 NPD12_712 bd5b4808f6346a22370f19f815f11430 638 SUPERFAMILY SSF56317 9 286 3.01E-40 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily NPD12_712 bd5b4808f6346a22370f19f815f11430 638 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 8 636 28.06 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 NPD12_712 bd5b4808f6346a22370f19f815f11430 638 Pfam PF02540 NAD synthase 339 573 3.7E-31 T 12-10-2018 IPR022310 NAD/GMP synthase NPD12_712 bd5b4808f6346a22370f19f815f11430 638 TIGRFAM TIGR00552 nadE: NAD+ synthetase 341 507 3.6E-27 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 NPD12_712 bd5b4808f6346a22370f19f815f11430 638 Gene3D G3DSA:3.40.50.620 314 528 8.0E-70 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_712 bd5b4808f6346a22370f19f815f11430 638 Pfam PF00795 Carbon-nitrogen hydrolase 19 272 2.3E-12 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 NPD12_712 bd5b4808f6346a22370f19f815f11430 638 Gene3D G3DSA:1.10.10.1140 544 638 4.9E-41 T 12-10-2018 NPD12_712 bd5b4808f6346a22370f19f815f11430 638 Gene3D G3DSA:3.60.110.10 2 308 6.4E-70 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily NPD12_712 bd5b4808f6346a22370f19f815f11430 638 PIRSF PIRSF006630 5 638 2.9E-170 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 NPD12_22 34bc956ffb43900febd2a569ece0e134 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 186 1.3E-27 T 12-10-2018 NPD12_22 34bc956ffb43900febd2a569ece0e134 214 SUPERFAMILY SSF56784 3 212 5.6E-40 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_22 34bc956ffb43900febd2a569ece0e134 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 130 146 4.0E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_22 34bc956ffb43900febd2a569ece0e134 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 4.0E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_22 34bc956ffb43900febd2a569ece0e134 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 148 168 4.0E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_22 34bc956ffb43900febd2a569ece0e134 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 4.0E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_22 34bc956ffb43900febd2a569ece0e134 214 Gene3D G3DSA:1.10.150.240 18 86 2.5E-45 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 NPD12_22 34bc956ffb43900febd2a569ece0e134 214 Gene3D G3DSA:3.40.50.1000 8 198 2.5E-45 T 12-10-2018 IPR023214 HAD superfamily NPD12_22 34bc956ffb43900febd2a569ece0e134 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 60 186 5.1E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 NPD12_1237 41852f3d1daeaa5a75c3f9706787ab37 317 Gene3D G3DSA:1.10.3470.10 3 316 3.4E-64 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1237 41852f3d1daeaa5a75c3f9706787ab37 317 SUPERFAMILY SSF81345 5 312 1.96E-67 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1237 41852f3d1daeaa5a75c3f9706787ab37 317 Pfam PF01032 FecCD transport family 10 311 3.0E-67 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_2306 161ed4455580e5aa4255e73685377b63 148 SUPERFAMILY SSF47413 1 65 2.82E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_2306 161ed4455580e5aa4255e73685377b63 148 SMART SM00530 6 61 2.2E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2306 161ed4455580e5aa4255e73685377b63 148 Pfam PF01381 Helix-turn-helix 9 61 1.9E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2306 161ed4455580e5aa4255e73685377b63 148 Gene3D G3DSA:1.10.260.40 1 64 2.2E-21 T 12-10-2018 NPD12_2255 d655b6028b41cbd33afdb3f866cdd932 98 SUPERFAMILY SSF143414 7 93 4.97E-27 T 12-10-2018 IPR037233 CcmK-like superfamily NPD12_2255 d655b6028b41cbd33afdb3f866cdd932 98 Pfam PF00936 BMC domain 8 83 1.2E-27 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2255 d655b6028b41cbd33afdb3f866cdd932 98 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 6 53 7.0E-17 T 12-10-2018 NPD12_2255 d655b6028b41cbd33afdb3f866cdd932 98 SMART SM00877 7 83 3.3E-34 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2255 d655b6028b41cbd33afdb3f866cdd932 98 Gene3D G3DSA:3.30.70.1710 2 97 5.6E-35 T 12-10-2018 NPD12_2785 4124366ff7b8c6d09e759947a088a075 148 SMART SM00260 3 140 1.0E-34 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_2785 4124366ff7b8c6d09e759947a088a075 148 SUPERFAMILY SSF50341 3 146 1.03E-34 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 NPD12_2785 4124366ff7b8c6d09e759947a088a075 148 Gene3D G3DSA:2.40.50.180 26 135 1.9E-37 T 12-10-2018 NPD12_2785 4124366ff7b8c6d09e759947a088a075 148 Gene3D G3DSA:2.30.30.40 9 134 1.9E-37 T 12-10-2018 NPD12_2785 4124366ff7b8c6d09e759947a088a075 148 Pfam PF01584 CheW-like domain 8 143 6.0E-33 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_2844 c82ab1473a971f782885617362d0598d 763 SUPERFAMILY SSF48168 8 234 5.62E-64 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 160 750 1.5E-179 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 PRINTS PR01183 Ribonucleotide reductase large chain signature 311 330 2.6E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 PRINTS PR01183 Ribonucleotide reductase large chain signature 505 528 2.6E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 PRINTS PR01183 Ribonucleotide reductase large chain signature 571 594 2.6E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 PRINTS PR01183 Ribonucleotide reductase large chain signature 632 659 2.6E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 565 2.6E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 PRINTS PR01183 Ribonucleotide reductase large chain signature 451 462 2.6E-38 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 SUPERFAMILY SSF51998 235 762 4.58E-164 T 12-10-2018 NPD12_2844 c82ab1473a971f782885617362d0598d 763 Gene3D G3DSA:3.20.70.20 88 757 5.6E-207 T 12-10-2018 NPD12_2844 c82ab1473a971f782885617362d0598d 763 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 157 231 1.7E-21 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 621 643 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 Pfam PF03477 ATP cone domain 3 102 8.1E-21 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 NPD12_2844 c82ab1473a971f782885617362d0598d 763 Pfam PF02867 Ribonucleotide reductase, barrel domain 236 747 1.3E-149 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 Gene3D G3DSA:1.10.10.10 1 89 3.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 Gene3D G3DSA:3.40.190.10 90 287 3.6E-32 T 12-10-2018 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 SUPERFAMILY SSF53850 89 293 1.9E-29 T 12-10-2018 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 Gene3D G3DSA:3.40.190.10 164 265 3.6E-32 T 12-10-2018 NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 Pfam PF03466 LysR substrate binding domain 90 289 1.2E-32 T 12-10-2018 IPR005119 LysR, substrate-binding NPD12_1218 d8f01ed14de02e99f10b632edc95e75d 297 SUPERFAMILY SSF46785 1 84 1.54E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3749 4ebb14baea840874a70c94826cdc15f8 255 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 135 246 3.7E-11 T 12-10-2018 IPR006528 Phage head morphogenesis domain NPD12_3749 4ebb14baea840874a70c94826cdc15f8 255 Pfam PF04233 Phage Mu protein F like protein 136 247 2.1E-15 T 12-10-2018 IPR006528 Phage head morphogenesis domain NPD12_3603 72430746191d520c980cdb1c230468e8 130 Gene3D G3DSA:3.30.230.10 1 130 3.6E-53 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_3603 72430746191d520c980cdb1c230468e8 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 NPD12_3603 72430746191d520c980cdb1c230468e8 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.2E-48 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 NPD12_3603 72430746191d520c980cdb1c230468e8 130 SUPERFAMILY SSF54211 6 130 4.55E-50 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3603 72430746191d520c980cdb1c230468e8 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.716 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid NPD12_2757 d52ba6ff0747ed1ba083e92eeaf9b93f 363 Gene3D G3DSA:3.40.50.20 20 110 8.1E-29 T 12-10-2018 NPD12_2757 d52ba6ff0747ed1ba083e92eeaf9b93f 363 Pfam PF15632 ATP-grasp in the biosynthetic pathway with Ter operon 12 334 2.9E-63 T 12-10-2018 IPR011226 ATP-grasp family NPD12_2757 d52ba6ff0747ed1ba083e92eeaf9b93f 363 SUPERFAMILY SSF56059 109 332 1.94E-24 T 12-10-2018 NPD12_2757 d52ba6ff0747ed1ba083e92eeaf9b93f 363 Gene3D G3DSA:3.30.1490.20 111 223 8.1E-29 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 NPD12_2757 d52ba6ff0747ed1ba083e92eeaf9b93f 363 Gene3D G3DSA:3.30.470.20 224 304 8.1E-29 T 12-10-2018 NPD12_3675 42fe9e4d9ec62f9345eb1670b0bcf7ca 151 Gene3D G3DSA:1.10.10.1240 2 72 3.3E-32 T 12-10-2018 NPD12_3675 42fe9e4d9ec62f9345eb1670b0bcf7ca 151 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 149 4.7E-54 T 12-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 NPD12_3675 42fe9e4d9ec62f9345eb1670b0bcf7ca 151 PIRSF PIRSF010607 1 151 1.5E-56 T 12-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 NPD12_3675 42fe9e4d9ec62f9345eb1670b0bcf7ca 151 Gene3D G3DSA:1.10.1200.150 73 151 8.1E-13 T 12-10-2018 NPD12_3288 32ebaec165bede71e1ea8223be2762d5 167 PIRSF PIRSF031501 1 165 3.2E-49 T 12-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 NPD12_3288 32ebaec165bede71e1ea8223be2762d5 167 Gene3D G3DSA:1.10.1760.20 2 162 7.4E-8 T 12-10-2018 NPD12_3288 32ebaec165bede71e1ea8223be2762d5 167 Pfam PF06177 QueT transporter 11 157 6.5E-48 T 12-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 NPD12_2032 20caf130f3b89cdef3e315f7594d17ce 398 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 2.4E-23 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 NPD12_2032 20caf130f3b89cdef3e315f7594d17ce 398 Pfam PF01548 Transposase 4 160 5.2E-40 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 NPD12_3028 20caf130f3b89cdef3e315f7594d17ce 398 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 2.4E-23 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 NPD12_3028 20caf130f3b89cdef3e315f7594d17ce 398 Pfam PF01548 Transposase 4 160 5.2E-40 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 Gene3D G3DSA:1.10.287.130 74 147 7.2E-20 T 12-10-2018 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 SUPERFAMILY SSF47384 72 147 5.3E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 Gene3D G3DSA:3.30.565.10 152 291 2.1E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 SUPERFAMILY SSF55874 152 286 3.8E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 SMART SM00388 81 147 2.3E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 193 285 5.6E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 Pfam PF00512 His Kinase A (phospho-acceptor) domain 86 146 3.0E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 PRINTS PR01780 Lantibiotic regulatory protein signature 189 204 1.1E-5 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 PRINTS PR01780 Lantibiotic regulatory protein signature 251 266 1.1E-5 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 PRINTS PR01780 Lantibiotic regulatory protein signature 90 106 1.1E-5 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 NPD12_965 2f21a65c52a96e8fbc94b25b9aef6c20 301 SMART SM00387 193 300 3.0E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2160 faab194e156178417a2db5e0cf9e34a3 363 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 348 9.8E-67 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 NPD12_2160 faab194e156178417a2db5e0cf9e34a3 363 PIRSF PIRSF000112 1 359 9.0E-93 T 12-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 NPD12_2160 faab194e156178417a2db5e0cf9e34a3 363 Gene3D G3DSA:1.20.1090.10 160 363 2.3E-80 T 12-10-2018 NPD12_2160 faab194e156178417a2db5e0cf9e34a3 363 Gene3D G3DSA:3.40.50.1970 2 159 3.8E-41 T 12-10-2018 NPD12_2160 faab194e156178417a2db5e0cf9e34a3 363 SUPERFAMILY SSF56796 3 355 1.44E-89 T 12-10-2018 NPD12_1453 4f62124dffc7e2370d8ac468b5ba7c00 383 Gene3D G3DSA:3.40.718.10 107 231 4.1E-12 T 12-10-2018 NPD12_1453 4f62124dffc7e2370d8ac468b5ba7c00 383 Pfam PF02504 Fatty acid synthesis protein 26 361 7.8E-69 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 NPD12_1453 4f62124dffc7e2370d8ac468b5ba7c00 383 SUPERFAMILY SSF53659 25 291 2.06E-27 T 12-10-2018 NPD12_1453 4f62124dffc7e2370d8ac468b5ba7c00 383 PIRSF PIRSF036593 1 383 2.2E-189 T 12-10-2018 IPR012116 Glycine/sarcosine/betaine reductase complex, protein C, alpha subunit NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.6E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 94 25.93 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 SUPERFAMILY SSF50129 1 94 8.67E-33 T 12-10-2018 IPR011032 GroES-like superfamily NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 SMART SM00883 2 93 6.1E-51 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 PRINTS PR00297 10kDa chaperonin signature 3 18 1.1E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 PRINTS PR00297 10kDa chaperonin signature 80 93 1.1E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 PRINTS PR00297 10kDa chaperonin signature 59 71 1.1E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 PRINTS PR00297 10kDa chaperonin signature 25 46 1.1E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 Gene3D G3DSA:2.30.33.40 1 95 5.2E-36 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 NPD12_3427 4b36266e206ebecb4f641329fd86800e 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 Pfam PF01327 Polypeptide deformylase 4 155 5.1E-38 T 12-10-2018 IPR023635 Peptide deformylase NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 Gene3D G3DSA:3.90.45.10 1 165 6.9E-37 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 SUPERFAMILY SSF56420 4 162 3.4E-41 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 PRINTS PR01576 Peptide deformylase signature 105 123 2.8E-12 T 12-10-2018 IPR023635 Peptide deformylase NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 PRINTS PR01576 Peptide deformylase signature 39 68 2.8E-12 T 12-10-2018 IPR023635 Peptide deformylase NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 PRINTS PR01576 Peptide deformylase signature 124 153 2.8E-12 T 12-10-2018 IPR023635 Peptide deformylase NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 PRINTS PR01576 Peptide deformylase signature 93 104 2.8E-12 T 12-10-2018 IPR023635 Peptide deformylase NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 Hamap MF_00163 Peptide deformylase [def]. 2 166 19.76 T 12-10-2018 IPR023635 Peptide deformylase NPD12_1053 7b0ebaec840b98da452fa3b1b1ee82c9 166 PIRSF PIRSF004749 1 165 5.6E-29 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2250 1149dcfca8fdd98a6739b85f0cab2ef4 117 SUPERFAMILY SSF143414 45 109 1.83E-15 T 12-10-2018 IPR037233 CcmK-like superfamily NPD12_2250 1149dcfca8fdd98a6739b85f0cab2ef4 117 Pfam PF00936 BMC domain 46 106 2.5E-15 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2250 1149dcfca8fdd98a6739b85f0cab2ef4 117 SMART SM00877 45 117 3.3E-21 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2250 1149dcfca8fdd98a6739b85f0cab2ef4 117 Gene3D G3DSA:3.30.70.1710 4 117 2.8E-47 T 12-10-2018 NPD12_2250 1149dcfca8fdd98a6739b85f0cab2ef4 117 PIRSF PIRSF012296 3 117 2.4E-53 T 12-10-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 NPD12_317 b558e0591c938e9fc6f2f9ae33566c41 84 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 NPD12_317 b558e0591c938e9fc6f2f9ae33566c41 84 SUPERFAMILY SSF46689 2 49 6.36E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_317 b558e0591c938e9fc6f2f9ae33566c41 84 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 80 1.1E-48 T 12-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID NPD12_317 b558e0591c938e9fc6f2f9ae33566c41 84 Gene3D G3DSA:1.10.10.60 1 84 3.0E-40 T 12-10-2018 NPD12_317 b558e0591c938e9fc6f2f9ae33566c41 84 Pfam PF12116 Stage III sporulation protein D 2 81 1.2E-44 T 12-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID NPD12_207 51e7d69e612c96645e181c3ed6a0085d 313 SUPERFAMILY SSF143865 1 247 1.83E-50 T 12-10-2018 NPD12_207 51e7d69e612c96645e181c3ed6a0085d 313 SUPERFAMILY SSF144083 248 310 5.62E-15 T 12-10-2018 NPD12_207 51e7d69e612c96645e181c3ed6a0085d 313 Gene3D G3DSA:1.20.58.340 256 312 1.7E-11 T 12-10-2018 NPD12_207 51e7d69e612c96645e181c3ed6a0085d 313 Pfam PF01544 CorA-like Mg2+ transporter protein 24 309 8.5E-51 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 NPD12_207 51e7d69e612c96645e181c3ed6a0085d 313 Gene3D G3DSA:1.20.58.340 133 254 2.2E-26 T 12-10-2018 NPD12_207 51e7d69e612c96645e181c3ed6a0085d 313 Gene3D G3DSA:3.30.460.20 1 132 1.9E-24 T 12-10-2018 NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 Gene3D G3DSA:3.40.50.300 210 310 1.2E-100 T 12-10-2018 NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 ProSitePatterns PS00211 ABC transporters family signature. 516 530 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 SUPERFAMILY SSF52540 334 596 4.59E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 Gene3D G3DSA:1.20.1580.10 1 209 1.2E-100 T 12-10-2018 NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 Gene3D G3DSA:1.20.1580.10 417 455 6.3E-105 T 12-10-2018 NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 Pfam PF00005 ABC transporter 340 543 1.7E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 SUPERFAMILY SSF52540 149 304 7.62E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 Gene3D G3DSA:1.10.8.280 21 131 1.2E-100 T 12-10-2018 NPD12_899 99a9bd95fa388197fa8a7d4b70f9b432 619 Gene3D G3DSA:3.40.50.300 335 619 6.3E-105 T 12-10-2018 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Pfam PF01411 tRNA synthetases class II (A) 8 558 4.1E-202 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 8.3E-30 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 197 208 8.3E-30 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 8.3E-30 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 8.3E-30 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 224 237 8.3E-30 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Gene3D G3DSA:3.30.980.10 558 697 9.0E-52 T 12-10-2018 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 SUPERFAMILY SSF55681 4 243 4.97E-94 T 12-10-2018 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Gene3D G3DSA:3.30.930.10 3 239 4.9E-99 T 12-10-2018 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 SUPERFAMILY SSF55186 554 718 2.88E-51 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 173.307 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 SMART SM00863 655 698 2.1E-22 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Gene3D G3DSA:3.30.54.20 626 679 9.0E-52 T 12-10-2018 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 SUPERFAMILY SSF50447 455 554 4.24E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 SUPERFAMILY SSF101353 244 462 5.49E-66 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Pfam PF02272 DHHA1 domain 740 873 1.0E-25 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 3.4E-301 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Gene3D G3DSA:3.10.310.40 766 876 8.6E-34 T 12-10-2018 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Gene3D G3DSA:2.40.30.130 478 554 1.8E-8 T 12-10-2018 NPD12_2610 760bb41bc5640d0ce681562ee55ea281 879 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 3.3E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 SMART SM00644 5 132 5.7E-8 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 Gene3D G3DSA:1.10.101.10 168 238 7.0E-18 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 SMART SM00701 6 126 3.1E-5 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 SUPERFAMILY SSF47090 168 234 9.94E-16 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 SUPERFAMILY SSF55846 14 135 1.24E-40 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 Gene3D G3DSA:3.40.80.10 16 141 6.8E-41 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 Pfam PF01471 Putative peptidoglycan binding domain 177 233 4.7E-12 T 12-10-2018 IPR002477 Peptidoglycan binding-like NPD12_930 2d633f07feb0c33ffeac52c404e03595 238 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 17 132 1.1E-21 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_1113 00749249de4dff93b292c1877598105c 244 SUPERFAMILY SSF52540 30 211 1.43E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1113 00749249de4dff93b292c1877598105c 244 Gene3D G3DSA:3.40.50.300 27 98 4.2E-11 T 12-10-2018 NPD12_1113 00749249de4dff93b292c1877598105c 244 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 154 198 4.5E-8 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_1113 00749249de4dff93b292c1877598105c 244 SMART SM00382 39 210 7.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1113 00749249de4dff93b292c1877598105c 244 Pfam PF13476 AAA domain 31 83 1.2E-11 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain NPD12_1113 00749249de4dff93b292c1877598105c 244 Gene3D G3DSA:3.40.50.300 119 224 3.6E-12 T 12-10-2018 NPD12_2613 394bc9c2ce7a1e9b163ade32b062a52d 142 Pfam PF01592 NifU-like N terminal domain 1 119 5.8E-51 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 NPD12_2613 394bc9c2ce7a1e9b163ade32b062a52d 142 SUPERFAMILY SSF82649 4 121 1.07E-47 T 12-10-2018 NPD12_2613 394bc9c2ce7a1e9b163ade32b062a52d 142 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 121 1.1E-70 T 12-10-2018 IPR017787 NIF system FeS cluster assembly, NifU-like NPD12_2613 394bc9c2ce7a1e9b163ade32b062a52d 142 Gene3D G3DSA:3.90.1010.10 1 141 5.3E-61 T 12-10-2018 NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 Pfam PF01628 HrcA protein C terminal domain 104 321 1.4E-58 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.473 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 Gene3D G3DSA:3.30.390.60 128 229 1.5E-53 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 333 3.7E-101 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 SUPERFAMILY SSF55781 70 337 5.3E-56 T 12-10-2018 NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 Gene3D G3DSA:1.10.10.10 1 84 9.7E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 PIRSF PIRSF005485 1 339 1.3E-106 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 Pfam PF08279 HTH domain 10 71 1.9E-5 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 SUPERFAMILY SSF46785 1 83 3.83E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3010 66d35aa7a9c4349665e59b682f77e78a 343 Gene3D G3DSA:3.30.450.40 105 334 1.5E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 Pfam PF13500 AAA domain 3 227 4.6E-19 T 12-10-2018 NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 SUPERFAMILY SSF52540 1 227 1.99E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 493 172.84 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 Gene3D G3DSA:3.40.50.300 2 240 2.2E-53 T 12-10-2018 NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 248 437 2.1E-62 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 SUPERFAMILY SSF52317 247 432 2.75E-34 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 486 4.6E-165 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 NPD12_1098 9b6d55536f12de62c53eefb3de8aac8d 493 Gene3D G3DSA:3.40.50.880 247 433 3.7E-21 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2020 cf040d93d7cdd6fe4770f9c4feabda26 217 PIRSF PIRSF038973 1 210 7.2E-70 T 12-10-2018 IPR014196 Stage II sporulation protein M NPD12_2020 cf040d93d7cdd6fe4770f9c4feabda26 217 Pfam PF01944 Stage II sporulation protein M 24 200 5.9E-26 T 12-10-2018 IPR002798 Stage II sporulation protein M-like NPD12_2020 cf040d93d7cdd6fe4770f9c4feabda26 217 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 8 205 3.3E-69 T 12-10-2018 IPR014196 Stage II sporulation protein M NPD12_1592 c8ebde9fe5413b651aec6728f80c559a 628 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 10 627 1.9E-252 T 12-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 NPD12_1592 c8ebde9fe5413b651aec6728f80c559a 628 Gene3D G3DSA:1.20.1270.30 61 232 5.4E-49 T 12-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 NPD12_1592 c8ebde9fe5413b651aec6728f80c559a 628 PIRSF PIRSF005023 1 628 7.4E-234 T 12-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 NPD12_1592 c8ebde9fe5413b651aec6728f80c559a 628 Gene3D G3DSA:3.40.50.2030 413 628 1.1E-68 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_1592 c8ebde9fe5413b651aec6728f80c559a 628 Gene3D G3DSA:3.40.50.2030 234 411 3.5E-45 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_1592 c8ebde9fe5413b651aec6728f80c559a 628 SUPERFAMILY SSF56821 20 627 3.82E-154 T 12-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 NPD12_1592 c8ebde9fe5413b651aec6728f80c559a 628 Pfam PF03063 Prismane/CO dehydrogenase family 47 608 4.0E-144 T 12-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PRINTS PR01469 Bacterial carbamate kinase signature 183 201 8.3E-63 T 12-10-2018 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PRINTS PR01469 Bacterial carbamate kinase signature 213 228 8.3E-63 T 12-10-2018 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PRINTS PR01469 Bacterial carbamate kinase signature 42 61 8.3E-63 T 12-10-2018 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PRINTS PR01469 Bacterial carbamate kinase signature 111 130 8.3E-63 T 12-10-2018 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PRINTS PR01469 Bacterial carbamate kinase signature 268 283 8.3E-63 T 12-10-2018 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PRINTS PR01469 Bacterial carbamate kinase signature 160 179 8.3E-63 T 12-10-2018 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PRINTS PR01469 Bacterial carbamate kinase signature 76 94 8.3E-63 T 12-10-2018 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 PIRSF PIRSF000723 1 314 4.9E-123 T 12-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 Gene3D G3DSA:3.40.1160.10 1 314 2.4E-121 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 SUPERFAMILY SSF53633 1 312 1.44E-81 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 Pfam PF00696 Amino acid kinase family 1 290 8.7E-30 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 NPD12_2640 3edf15dd3392e475ef30f3be5f9792b2 314 TIGRFAM TIGR00746 arcC: carbamate kinase 1 313 6.4E-120 T 12-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 NPD12_1369 73aa7a85f51541606fdb59f2b1906101 376 PIRSF PIRSF005572 2 376 3.1E-127 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 NPD12_1369 73aa7a85f51541606fdb59f2b1906101 376 SUPERFAMILY SSF53383 3 376 6.31E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1369 73aa7a85f51541606fdb59f2b1906101 376 Gene3D G3DSA:3.40.640.10 16 257 1.4E-148 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1369 73aa7a85f51541606fdb59f2b1906101 376 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site NPD12_1369 73aa7a85f51541606fdb59f2b1906101 376 Gene3D G3DSA:3.90.1150.10 5 374 1.4E-148 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1369 73aa7a85f51541606fdb59f2b1906101 376 Pfam PF00266 Aminotransferase class-V 5 365 2.7E-87 T 12-10-2018 IPR000192 Aminotransferase class V domain NPD12_3651 3a5b63db378766b972c6803994116afb 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.6E-31 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal NPD12_3651 3a5b63db378766b972c6803994116afb 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 2.0E-15 T 12-10-2018 NPD12_3651 3a5b63db378766b972c6803994116afb 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 1.7E-65 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3651 3a5b63db378766b972c6803994116afb 141 SUPERFAMILY SSF46906 67 140 1.44E-27 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily NPD12_3651 3a5b63db378766b972c6803994116afb 141 SMART SM00649 9 140 3.2E-86 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 NPD12_3651 3a5b63db378766b972c6803994116afb 141 Gene3D G3DSA:1.10.10.250 72 140 1.1E-29 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily NPD12_3651 3a5b63db378766b972c6803994116afb 141 Gene3D G3DSA:3.30.1550.10 2 71 1.2E-34 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily NPD12_3651 3a5b63db378766b972c6803994116afb 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.829 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 NPD12_3651 3a5b63db378766b972c6803994116afb 141 SUPERFAMILY SSF54747 3 72 8.11E-31 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily NPD12_3651 3a5b63db378766b972c6803994116afb 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.2E-26 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 NPD12_1172 cd3ac2dacd7293b9c2f42ddad88339ec 284 SUPERFAMILY SSF55729 32 147 1.64E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1172 cd3ac2dacd7293b9c2f42ddad88339ec 284 Pfam PF13673 Acetyltransferase (GNAT) domain 193 273 3.6E-8 T 12-10-2018 IPR000182 GNAT domain NPD12_1172 cd3ac2dacd7293b9c2f42ddad88339ec 284 SUPERFAMILY SSF55729 157 272 7.04E-12 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1172 cd3ac2dacd7293b9c2f42ddad88339ec 284 Gene3D G3DSA:3.40.630.30 155 283 3.5E-11 T 12-10-2018 NPD12_1172 cd3ac2dacd7293b9c2f42ddad88339ec 284 Gene3D G3DSA:3.40.630.30 4 150 2.9E-16 T 12-10-2018 NPD12_1172 cd3ac2dacd7293b9c2f42ddad88339ec 284 Pfam PF00583 Acetyltransferase (GNAT) family 49 133 6.6E-9 T 12-10-2018 IPR000182 GNAT domain NPD12_2811 5c4da30da64e6372785ecf14e5a24942 429 SUPERFAMILY SSF63825 227 404 7.72E-13 T 12-10-2018 NPD12_2811 5c4da30da64e6372785ecf14e5a24942 429 Pfam PF16472 Domain of unknown function (DUF5050) 96 369 1.8E-43 T 12-10-2018 IPR032485 Domain of unknown function DUF5050 NPD12_2811 5c4da30da64e6372785ecf14e5a24942 429 Gene3D G3DSA:2.120.10.30 95 240 3.7E-6 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like NPD12_2811 5c4da30da64e6372785ecf14e5a24942 429 SUPERFAMILY SSF63825 104 262 8.24E-9 T 12-10-2018 NPD12_2811 5c4da30da64e6372785ecf14e5a24942 429 Gene3D G3DSA:2.120.10.30 275 407 1.7E-6 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like NPD12_3197 20e4e0198dc9d4d28776ba6f4cf0d388 140 SUPERFAMILY SSF55874 31 135 1.05E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_3197 20e4e0198dc9d4d28776ba6f4cf0d388 140 Gene3D G3DSA:3.30.565.10 2 139 1.7E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_3197 20e4e0198dc9d4d28776ba6f4cf0d388 140 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 3 137 6.1E-69 T 12-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 NPD12_3197 20e4e0198dc9d4d28776ba6f4cf0d388 140 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 2 140 34.187 T 12-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 NPD12_3197 20e4e0198dc9d4d28776ba6f4cf0d388 140 Pfam PF13581 Histidine kinase-like ATPase domain 15 137 1.3E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 Pfam PF01938 TRAM domain 8 62 1.9E-6 T 12-10-2018 IPR002792 TRAM domain NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 278 458 1.6E-20 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 22 451 7.2E-158 T 12-10-2018 NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 441 451 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 SUPERFAMILY SSF50249 2 63 1.43E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 Gene3D G3DSA:3.40.50.150 85 453 1.5E-126 T 12-10-2018 NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 Gene3D G3DSA:2.40.50.140 1 63 1.0E-18 T 12-10-2018 NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 389 420 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 SUPERFAMILY SSF53335 72 457 7.36E-87 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3524 580059146d4eeef86ea04f5568a9cf09 461 Gene3D G3DSA:3.40.1350.30 134 290 1.5E-126 T 12-10-2018 NPD12_830 aaefd5b0c3be750691b9313b89fa117c 906 SUPERFAMILY SSF51556 519 850 9.83E-20 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_830 aaefd5b0c3be750691b9313b89fa117c 906 Gene3D G3DSA:3.20.20.140 368 644 7.7E-16 T 12-10-2018 NPD12_830 aaefd5b0c3be750691b9313b89fa117c 906 Gene3D G3DSA:3.20.20.140 691 883 5.0E-18 T 12-10-2018 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 SUPERFAMILY SSF52518 5 258 1.68E-79 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 269 374 2.2E-16 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 5 1171 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 959 1069 3.0E-9 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Gene3D G3DSA:3.40.50.970 2 258 7.1E-111 T 12-10-2018 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Gene3D G3DSA:3.40.50.970 786 1172 1.3E-174 T 12-10-2018 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 247 8.1E-81 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Gene3D G3DSA:3.40.920.10 415 625 5.9E-94 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 SUPERFAMILY SSF54862 665 832 1.36E-21 T 12-10-2018 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 SUPERFAMILY SSF52518 787 1170 1.3E-135 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 425 608 5.1E-32 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 745 756 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 SUPERFAMILY SSF53323 415 668 1.7E-89 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 SUPERFAMILY SSF52922 259 414 1.26E-48 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Pfam PF12838 4Fe-4S dicluster domain 688 757 1.2E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 SMART SM00890 621 679 2.1E-31 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Gene3D G3DSA:3.30.70.20 669 785 2.7E-43 T 12-10-2018 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Gene3D G3DSA:4.10.780.10 629 668 1.2E-6 T 12-10-2018 IPR037112 Pyruvate-flavodoxin oxidoreductase, EKR domain superfamily NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Pfam PF10371 Domain of unknown function 625 678 4.4E-24 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 Gene3D G3DSA:3.40.50.920 259 413 1.2E-57 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_1380 7fbb3df81ab2d3bd0b8e3121d8ddbac2 1172 PIRSF PIRSF000159 1 1172 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 Gene3D G3DSA:3.20.80.10 120 272 3.7E-19 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 Pfam PF13411 MerR HTH family regulatory protein 5 72 7.6E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 SUPERFAMILY SSF46955 4 111 4.76E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 SMART SM00871 122 271 7.6E-10 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 Pfam PF06445 GyrI-like small molecule binding domain 125 269 2.1E-9 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 Gene3D G3DSA:1.10.1660.10 4 113 1.0E-25 T 12-10-2018 NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 SUPERFAMILY SSF55136 129 269 3.31E-25 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_1207 fa2ef5611d7696b1d33c731705263b64 273 SMART SM00422 5 75 1.5E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_3758 d9b5b86c4d16d0308ac3afa5d4a736ef 183 Pfam PF07659 Domain of Unknown Function (DUF1599) 116 180 1.4E-17 T 12-10-2018 IPR011630 Clostridium phage phiCTP1, Gp74 NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 PRINTS PR00721 Stomatin signature 128 151 9.4E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 PRINTS PR00721 Stomatin signature 108 125 9.4E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 PRINTS PR00721 Stomatin signature 73 94 9.4E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 PRINTS PR00721 Stomatin signature 152 170 9.4E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 PRINTS PR00721 Stomatin signature 171 192 9.4E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 Pfam PF01145 SPFH domain / Band 7 family 22 193 1.0E-39 T 12-10-2018 IPR001107 Band 7 domain NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 Gene3D G3DSA:3.30.479.30 46 178 1.2E-41 T 12-10-2018 NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 SUPERFAMILY SSF117892 49 183 1.11E-40 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily NPD12_714 ff5f11443e8c2d87086126ae6367500d 312 SMART SM00244 18 176 6.9E-52 T 12-10-2018 IPR001107 Band 7 domain NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Gene3D G3DSA:3.30.230.10 479 675 2.0E-84 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Pfam PF14492 Elongation Factor G, domain II 399 471 8.2E-23 T 12-10-2018 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Gene3D G3DSA:3.30.70.870 408 478 2.0E-18 T 12-10-2018 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Pfam PF03764 Elongation factor G, domain IV 474 592 2.9E-45 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 SMART SM00889 475 592 1.3E-67 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 PRINTS PR00315 GTP-binding elongation factor signature 10 23 2.6E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 PRINTS PR00315 GTP-binding elongation factor signature 76 86 2.6E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 PRINTS PR00315 GTP-binding elongation factor signature 92 103 2.6E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 PRINTS PR00315 GTP-binding elongation factor signature 128 137 2.6E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 SUPERFAMILY SSF54211 477 593 2.25E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Gene3D G3DSA:2.40.30.10 289 407 2.8E-36 T 12-10-2018 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Gene3D G3DSA:3.30.70.240 598 669 2.0E-84 T 12-10-2018 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 177 1.1E-16 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 SUPERFAMILY SSF52540 4 277 3.14E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 678 1.1E-216 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 SUPERFAMILY SSF54980 399 477 3.06E-18 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 SUPERFAMILY SSF50447 261 399 5.16E-29 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 SUPERFAMILY SSF54980 597 674 6.71E-24 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Pfam PF00679 Elongation factor G C-terminus 595 674 1.2E-26 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 SMART SM00838 594 682 3.8E-31 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Pfam PF00009 Elongation factor Tu GTP binding domain 7 277 2.8E-40 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3677 b5bf2e869931d8fd1192c266b85afec5 690 Gene3D G3DSA:3.40.50.300 2 288 5.9E-78 T 12-10-2018 NPD12_371 2866ca712d29eddc87beb17f9919e354 344 Gene3D G3DSA:3.40.630.10 15 341 4.4E-116 T 12-10-2018 NPD12_371 2866ca712d29eddc87beb17f9919e354 344 Gene3D G3DSA:2.40.30.40 77 172 4.4E-116 T 12-10-2018 IPR023367 Peptidase M42, domain 2 NPD12_371 2866ca712d29eddc87beb17f9919e354 344 SUPERFAMILY SSF53187 8 343 3.14E-54 T 12-10-2018 NPD12_371 2866ca712d29eddc87beb17f9919e354 344 PIRSF PIRSF001123 5 344 2.5E-39 T 12-10-2018 IPR008007 Peptidase M42 NPD12_371 2866ca712d29eddc87beb17f9919e354 344 Pfam PF05343 M42 glutamyl aminopeptidase 49 337 9.3E-81 T 12-10-2018 IPR008007 Peptidase M42 NPD12_371 2866ca712d29eddc87beb17f9919e354 344 SUPERFAMILY SSF101821 74 187 2.14E-28 T 12-10-2018 NPD12_2335 7d432ed1267d0d6c0d6030c98e2ec0fc 461 SUPERFAMILY SSF141523 338 459 1.03E-32 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_2335 7d432ed1267d0d6c0d6030c98e2ec0fc 461 Gene3D G3DSA:1.10.269.20 214 334 3.5E-37 T 12-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily NPD12_2335 7d432ed1267d0d6c0d6030c98e2ec0fc 461 Gene3D G3DSA:2.40.440.10 340 460 1.6E-39 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_2335 7d432ed1267d0d6c0d6030c98e2ec0fc 461 Pfam PF03734 L,D-transpeptidase catalytic domain 341 458 3.5E-19 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 NPD12_2335 7d432ed1267d0d6c0d6030c98e2ec0fc 461 SUPERFAMILY SSF143985 214 332 2.35E-40 T 12-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily NPD12_2335 7d432ed1267d0d6c0d6030c98e2ec0fc 461 Pfam PF12229 Putative peptidoglycan binding domain 80 192 1.5E-15 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain NPD12_2335 7d432ed1267d0d6c0d6030c98e2ec0fc 461 Pfam PF12229 Putative peptidoglycan binding domain 205 320 2.5E-26 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain NPD12_2129 68f80e0c4186bc3925ba7b7ca63fa902 142 SUPERFAMILY SSF81301 24 105 9.81E-14 T 12-10-2018 NPD12_2129 68f80e0c4186bc3925ba7b7ca63fa902 142 Gene3D G3DSA:3.30.460.10 7 116 2.8E-15 T 12-10-2018 NPD12_2129 68f80e0c4186bc3925ba7b7ca63fa902 142 Pfam PF01909 Nucleotidyltransferase domain 21 104 1.4E-8 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 NPD12_674 22c9c04f5b4454c12d9bcf93c0da1c19 194 Pfam PF01966 HD domain 26 144 4.8E-17 T 12-10-2018 IPR006674 HD domain NPD12_674 22c9c04f5b4454c12d9bcf93c0da1c19 194 Gene3D G3DSA:1.10.3210.10 3 185 2.8E-58 T 12-10-2018 NPD12_674 22c9c04f5b4454c12d9bcf93c0da1c19 194 TIGRFAM TIGR00277 HDIG: HDIG domain 24 114 6.2E-9 T 12-10-2018 IPR006675 HDIG domain NPD12_674 22c9c04f5b4454c12d9bcf93c0da1c19 194 SMART SM00471 20 154 1.7E-9 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_674 22c9c04f5b4454c12d9bcf93c0da1c19 194 SUPERFAMILY SSF109604 22 182 1.96E-34 T 12-10-2018 NPD12_1132 879dea9909974e9c7185afebfa3fca39 238 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 20 236 4.3E-54 T 12-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 NPD12_1132 879dea9909974e9c7185afebfa3fca39 238 Gene3D G3DSA:3.30.950.10 144 238 2.0E-10 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 NPD12_1132 879dea9909974e9c7185afebfa3fca39 238 SUPERFAMILY SSF53790 20 236 1.57E-45 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 NPD12_1132 879dea9909974e9c7185afebfa3fca39 238 PIRSF PIRSF036427 18 238 2.9E-63 T 12-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 NPD12_1132 879dea9909974e9c7185afebfa3fca39 238 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 21 222 3.4E-43 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 NPD12_1132 879dea9909974e9c7185afebfa3fca39 238 Gene3D G3DSA:3.40.1010.10 19 143 3.7E-34 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 NPD12_3297 cf06e4ce813d05553f37c3f865d03510 242 SUPERFAMILY SSF52113 160 232 3.18E-10 T 12-10-2018 IPR036420 BRCT domain superfamily NPD12_3297 cf06e4ce813d05553f37c3f865d03510 242 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 164 230 1.6E-7 T 12-10-2018 IPR001357 BRCT domain NPD12_3297 cf06e4ce813d05553f37c3f865d03510 242 SMART SM00292 158 234 0.0012 T 12-10-2018 IPR001357 BRCT domain NPD12_3297 cf06e4ce813d05553f37c3f865d03510 242 SUPERFAMILY SSF47781 6 136 3.78E-21 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_3297 cf06e4ce813d05553f37c3f865d03510 242 Gene3D G3DSA:3.40.50.10190 154 241 9.5E-14 T 12-10-2018 IPR036420 BRCT domain superfamily NPD12_3297 cf06e4ce813d05553f37c3f865d03510 242 Gene3D G3DSA:1.10.150.20 4 75 5.7E-10 T 12-10-2018 NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 Gene3D G3DSA:3.40.50.300 214 403 9.0E-50 T 12-10-2018 NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 Pfam PF00271 Helicase conserved C-terminal domain 233 340 2.1E-27 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 SMART SM00487 20 223 2.5E-59 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 Pfam PF00270 DEAD/DEAH box helicase 25 197 1.3E-51 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 SMART SM00490 259 340 4.9E-32 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 SUPERFAMILY SSF52540 75 361 1.8E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_816 c638929d50e6177b677e2e73a908ccbb 425 Gene3D G3DSA:3.40.50.300 1 211 1.4E-75 T 12-10-2018 NPD12_799 3fa529a18ea94c878ff634bfb67c0828 109 Pfam PF01588 Putative tRNA binding domain 12 107 1.4E-15 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 NPD12_799 3fa529a18ea94c878ff634bfb67c0828 109 SUPERFAMILY SSF50249 1 108 1.22E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_799 3fa529a18ea94c878ff634bfb67c0828 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 108 5.6E-49 T 12-10-2018 IPR008231 Probable chaperone CsaA NPD12_799 3fa529a18ea94c878ff634bfb67c0828 109 Gene3D G3DSA:2.40.50.140 1 109 2.3E-31 T 12-10-2018 NPD12_214 a97e2576e916ead4ff70251d1d9d1bf2 314 SUPERFAMILY SSF52540 19 174 3.2E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_214 a97e2576e916ead4ff70251d1d9d1bf2 314 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 230 312 5.3E-6 T 12-10-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_214 a97e2576e916ead4ff70251d1d9d1bf2 314 Gene3D G3DSA:3.40.50.300 2 150 8.2E-40 T 12-10-2018 NPD12_214 a97e2576e916ead4ff70251d1d9d1bf2 314 Pfam PF13177 DNA polymerase III, delta subunit 9 152 2.6E-33 T 12-10-2018 NPD12_3714 f32bee574311051c44f7475adecf2fe7 209 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 3 190 1.5E-52 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_3714 f32bee574311051c44f7475adecf2fe7 209 Pfam PF02511 Thymidylate synthase complementing protein 5 188 5.0E-59 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_3714 f32bee574311051c44f7475adecf2fe7 209 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 208 26.094 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_3714 f32bee574311051c44f7475adecf2fe7 209 Gene3D G3DSA:3.30.1360.170 1 197 1.4E-61 T 12-10-2018 NPD12_3714 f32bee574311051c44f7475adecf2fe7 209 SUPERFAMILY SSF69796 1 188 1.83E-54 T 12-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_770 bef0bac70203c06764737caac6bee672 288 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 279 1.9E-88 T 12-10-2018 IPR003797 DegV NPD12_770 bef0bac70203c06764737caac6bee672 288 Gene3D G3DSA:3.40.50.10170 1 152 2.4E-48 T 12-10-2018 NPD12_770 bef0bac70203c06764737caac6bee672 288 SUPERFAMILY SSF82549 2 280 8.89E-78 T 12-10-2018 NPD12_770 bef0bac70203c06764737caac6bee672 288 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 280 1.1E-84 T 12-10-2018 IPR003797 DegV NPD12_770 bef0bac70203c06764737caac6bee672 288 Gene3D G3DSA:3.30.1180.10 153 285 3.5E-39 T 12-10-2018 NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 8.8E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 Pfam PF03466 LysR substrate binding domain 89 293 5.9E-30 T 12-10-2018 IPR005119 LysR, substrate-binding NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 Gene3D G3DSA:3.40.190.290 91 300 3.0E-32 T 12-10-2018 NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 Gene3D G3DSA:1.10.10.10 1 89 2.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 SUPERFAMILY SSF46785 1 87 5.45E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_59 36a2a85c0e07c258f97b8833c5f3012e 301 SUPERFAMILY SSF53850 91 295 5.83E-29 T 12-10-2018 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 SUPERFAMILY SSF46557 2 76 5.89E-20 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 Gene3D G3DSA:1.10.287.180 1 75 8.3E-23 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 Pfam PF03449 Transcription elongation factor, N-terminal 4 73 1.7E-19 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 PIRSF PIRSF006092 1 154 3.8E-47 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 Gene3D G3DSA:3.10.50.30 76 154 1.9E-16 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 153 3.1E-19 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 Hamap MF_00105 Transcription elongation factor GreA [greA]. 1 154 28.005 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 153 5.2E-42 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 NPD12_854 9321f58962bf5a04c7841d017a660cb0 154 SUPERFAMILY SSF54534 80 153 6.67E-15 T 12-10-2018 NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 SMART SM00388 123 189 1.4E-5 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 Gene3D G3DSA:3.30.565.10 194 343 5.6E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 1.4E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 1.4E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 1.4E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 1.4E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 SUPERFAMILY SSF47384 108 189 7.65E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 340 1.1E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 SMART SM00387 234 343 2.1E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 SUPERFAMILY SSF55874 180 340 7.33E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_696 5a1c348605a80a90ff2c7a8aaeef2db2 343 Gene3D G3DSA:1.10.287.130 114 188 7.2E-10 T 12-10-2018 NPD12_2693 940f7ed84ef114ee435e00a66a93c093 286 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 23 261 2.0E-22 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 NPD12_2693 940f7ed84ef114ee435e00a66a93c093 286 PIRSF PIRSF003092 1 286 1.1E-94 T 12-10-2018 IPR025501 ATP binding protein MinD NPD12_2693 940f7ed84ef114ee435e00a66a93c093 286 Gene3D G3DSA:3.40.50.300 21 262 4.4E-58 T 12-10-2018 NPD12_2693 940f7ed84ef114ee435e00a66a93c093 286 SUPERFAMILY SSF52540 22 268 3.67E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3650 24aa586355096b4616c150807e00f803 229 Pfam PF00687 Ribosomal protein L1p/L10e family 28 218 1.3E-59 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein NPD12_3650 24aa586355096b4616c150807e00f803 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 227 44.82 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 NPD12_3650 24aa586355096b4616c150807e00f803 229 Gene3D G3DSA:3.30.190.20 18 223 4.9E-90 T 12-10-2018 NPD12_3650 24aa586355096b4616c150807e00f803 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 224 2.4E-106 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 NPD12_3650 24aa586355096b4616c150807e00f803 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 118 137 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3650 24aa586355096b4616c150807e00f803 229 Gene3D G3DSA:3.40.50.790 65 157 4.9E-90 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich NPD12_3650 24aa586355096b4616c150807e00f803 229 SUPERFAMILY SSF56808 3 224 5.62E-87 T 12-10-2018 IPR023674 Ribosomal protein L1-like NPD12_3650 24aa586355096b4616c150807e00f803 229 PIRSF PIRSF002155 1 224 3.7E-82 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3805 13d44d41b6750c08e7d3bd0d0860f5cc 127 SUPERFAMILY SSF47413 6 73 3.38E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3805 13d44d41b6750c08e7d3bd0d0860f5cc 127 Gene3D G3DSA:1.10.260.40 5 93 2.8E-18 T 12-10-2018 NPD12_3805 13d44d41b6750c08e7d3bd0d0860f5cc 127 Pfam PF13560 Helix-turn-helix domain 9 65 1.7E-11 T 12-10-2018 NPD12_3805 13d44d41b6750c08e7d3bd0d0860f5cc 127 SMART SM00530 13 68 9.1E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 SUPERFAMILY SSF46785 10 80 6.72E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 Gene3D G3DSA:1.10.10.10 1 77 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 SMART SM00345 17 76 6.6E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 4.0E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 Pfam PF00155 Aminotransferase class I and II 140 468 3.4E-29 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 Gene3D G3DSA:3.40.640.10 156 375 6.2E-99 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 SUPERFAMILY SSF53383 97 481 2.67E-84 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2302 bc6a792a30c31b95681d954441538f5a 497 Gene3D G3DSA:3.90.1150.10 118 482 6.2E-99 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_3012 d07641ced5558456403ff84764b07217 602 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 180 3.1E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 Gene3D G3DSA:3.30.70.2570 485 559 1.9E-35 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily NPD12_3012 d07641ced5558456403ff84764b07217 602 SUPERFAMILY SSF54980 404 499 1.82E-24 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3012 d07641ced5558456403ff84764b07217 602 Pfam PF00009 Elongation factor Tu GTP binding domain 8 186 3.9E-53 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 Gene3D G3DSA:3.30.70.870 291 372 4.6E-35 T 12-10-2018 NPD12_3012 d07641ced5558456403ff84764b07217 602 Pfam PF06421 GTP-binding protein LepA C-terminus 493 599 3.6E-51 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal NPD12_3012 d07641ced5558456403ff84764b07217 602 Gene3D G3DSA:2.40.30.10 191 290 5.6E-38 T 12-10-2018 NPD12_3012 d07641ced5558456403ff84764b07217 602 Pfam PF00679 Elongation factor G C-terminus 405 491 2.6E-24 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_3012 d07641ced5558456403ff84764b07217 602 Gene3D G3DSA:3.40.50.300 5 190 1.5E-72 T 12-10-2018 NPD12_3012 d07641ced5558456403ff84764b07217 602 SUPERFAMILY SSF52540 6 225 6.21E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3012 d07641ced5558456403ff84764b07217 602 Gene3D G3DSA:3.30.70.3380 373 484 1.4E-40 T 12-10-2018 NPD12_3012 d07641ced5558456403ff84764b07217 602 Hamap MF_00071 Elongation factor 4 [lepA]. 1 602 305.141 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 SUPERFAMILY SSF54980 298 375 1.15E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3012 d07641ced5558456403ff84764b07217 602 SMART SM00838 402 491 2.3E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_3012 d07641ced5558456403ff84764b07217 602 Pfam PF03144 Elongation factor Tu domain 2 210 280 7.8E-11 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 TIGRFAM TIGR01393 lepA: elongation factor 4 8 601 0.0 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 NPD12_3012 d07641ced5558456403ff84764b07217 602 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site NPD12_3730 3c335ae0bbdf986fe4bbef806044b3d4 414 Pfam PF17288 Terminase RNAseH like domain 260 401 2.6E-28 T 12-10-2018 IPR035413 Phage terminase large subunit, C-terminal NPD12_3730 3c335ae0bbdf986fe4bbef806044b3d4 414 Pfam PF04466 Phage terminase large subunit 22 224 5.3E-58 T 12-10-2018 IPR035412 Phage terminase large subunit, N-terminal NPD12_3730 3c335ae0bbdf986fe4bbef806044b3d4 414 Gene3D G3DSA:3.30.420.280 231 409 7.8E-53 T 12-10-2018 NPD12_3730 3c335ae0bbdf986fe4bbef806044b3d4 414 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 24 400 3.6E-58 T 12-10-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 NPD12_3730 3c335ae0bbdf986fe4bbef806044b3d4 414 Gene3D G3DSA:3.40.50.300 10 227 5.3E-62 T 12-10-2018 NPD12_760 8ab3458a3d99175f4f167b86a9003d54 196 Pfam PF01433 Peptidase family M1 domain 68 147 2.7E-6 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 NPD12_760 8ab3458a3d99175f4f167b86a9003d54 196 Gene3D G3DSA:1.10.390.60 11 190 6.3E-7 T 12-10-2018 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 Gene3D G3DSA:3.40.50.140 2 163 3.7E-49 T 12-10-2018 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 Gene3D G3DSA:1.10.460.10 170 596 3.8E-126 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 315 329 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 SMART SM00436 135 229 5.7E-22 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 Gene3D G3DSA:2.70.20.10 223 480 3.8E-126 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 SUPERFAMILY SSF56712 3 603 5.62E-158 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 Pfam PF01751 Toprim domain 4 144 4.5E-17 T 12-10-2018 IPR006171 TOPRIM domain NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 Pfam PF01131 DNA topoisomerase 162 589 1.0E-106 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 109 122 1.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 199 217 1.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 320 329 1.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 516 530 1.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 395 411 1.6E-20 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 Gene3D G3DSA:1.10.290.10 286 409 3.8E-126 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 SMART SM00493 2 135 1.8E-17 T 12-10-2018 IPR006171 TOPRIM domain NPD12_1753 0f73a54fb1b49829581a30bd9625e955 619 SMART SM00437 277 553 2.2E-54 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 Gene3D G3DSA:3.30.420.40 33 273 1.5E-103 T 12-10-2018 NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 Gene3D G3DSA:3.30.420.40 146 259 1.5E-103 T 12-10-2018 NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 SUPERFAMILY SSF53067 144 273 1.36E-27 T 12-10-2018 NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 TIGRFAM TIGR02529 EutJ: ethanolamine utilization protein EutJ family protein 36 274 1.8E-98 T 12-10-2018 IPR013366 Ethanolamine utilisation EutJ NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 SUPERFAMILY SSF53067 34 136 2.07E-12 T 12-10-2018 NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 147 160 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 Pfam PF11104 Type IV pilus assembly protein PilM; 142 257 2.8E-12 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM NPD12_2247 e8426206d98c886f2d38435a2f443b6e 281 SMART SM00842 34 140 0.0086 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 NPD12_2505 4ce37e0a7da6846914865996cc64c025 335 Gene3D G3DSA:3.40.718.10 1 334 5.2E-135 T 12-10-2018 NPD12_2505 4ce37e0a7da6846914865996cc64c025 335 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 146.322 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 NPD12_2505 4ce37e0a7da6846914865996cc64c025 335 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 332 1.3E-117 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 NPD12_2505 4ce37e0a7da6846914865996cc64c025 335 SUPERFAMILY SSF53659 1 332 3.66E-102 T 12-10-2018 NPD12_2505 4ce37e0a7da6846914865996cc64c025 335 PIRSF PIRSF002465 1 334 2.0E-127 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 NPD12_2505 4ce37e0a7da6846914865996cc64c025 335 Pfam PF02504 Fatty acid synthesis protein 1 319 5.1E-114 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 Pfam PF01434 Peptidase family M41 389 597 9.6E-79 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 SUPERFAMILY SSF52540 151 398 1.97E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 SUPERFAMILY SSF140990 409 600 8.11E-72 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 Gene3D G3DSA:3.40.50.300 146 327 1.3E-71 T 12-10-2018 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 195 326 9.3E-46 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 Gene3D G3DSA:1.20.58.760 409 601 3.5E-75 T 12-10-2018 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 601 37.687 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 106 598 6.3E-237 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 Gene3D G3DSA:1.10.8.60 329 406 1.7E-28 T 12-10-2018 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 ProSitePatterns PS00674 AAA-protein family signature. 298 316 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 NPD12_3698 3bab7d41e63fdc15814829c46262944f 601 SMART SM00382 191 330 1.1E-26 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3512 77a9145a683ab45abf66bc4183ff3460 178 Pfam PF01613 Flavin reductase like domain 15 173 1.1E-9 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 NPD12_3512 77a9145a683ab45abf66bc4183ff3460 178 SUPERFAMILY SSF50475 13 176 4.46E-20 T 12-10-2018 NPD12_3512 77a9145a683ab45abf66bc4183ff3460 178 Gene3D G3DSA:2.30.110.10 1 177 6.1E-28 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_112 0742354346baa19707bf5611293fbe1a 384 Gene3D G3DSA:3.40.640.10 17 270 2.8E-111 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_112 0742354346baa19707bf5611293fbe1a 384 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 3 380 7.5E-150 T 12-10-2018 IPR010969 Cysteine desulfurase-related, unknown function NPD12_112 0742354346baa19707bf5611293fbe1a 384 Pfam PF00266 Aminotransferase class-V 3 371 5.9E-83 T 12-10-2018 IPR000192 Aminotransferase class V domain NPD12_112 0742354346baa19707bf5611293fbe1a 384 SUPERFAMILY SSF53383 3 383 5.24E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_112 0742354346baa19707bf5611293fbe1a 384 PIRSF PIRSF005572 1 384 2.9E-51 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 NPD12_112 0742354346baa19707bf5611293fbe1a 384 Gene3D G3DSA:3.90.1150.10 3 373 2.8E-111 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_155 cad03837b246908ece87857e9e6c6012 282 SUPERFAMILY SSF52540 6 223 2.81E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_155 cad03837b246908ece87857e9e6c6012 282 Gene3D G3DSA:3.40.50.300 1 233 2.1E-54 T 12-10-2018 NPD12_155 cad03837b246908ece87857e9e6c6012 282 SMART SM00382 32 213 1.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_155 cad03837b246908ece87857e9e6c6012 282 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_155 cad03837b246908ece87857e9e6c6012 282 Pfam PF00005 ABC transporter 23 165 5.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1959 6aebeed0929f3aa55017121f59758135 123 PIRSF PIRSF005965 1 123 1.1E-39 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 NPD12_1959 6aebeed0929f3aa55017121f59758135 123 Pfam PF07736 Chorismate mutase type I 1 119 4.8E-38 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 NPD12_1959 6aebeed0929f3aa55017121f59758135 123 Gene3D G3DSA:3.30.1330.40 1 123 8.5E-39 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 NPD12_1959 6aebeed0929f3aa55017121f59758135 123 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 119 9.3E-32 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 NPD12_1959 6aebeed0929f3aa55017121f59758135 123 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 7 119 4.0E-23 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 NPD12_1959 6aebeed0929f3aa55017121f59758135 123 SUPERFAMILY SSF55298 2 120 1.02E-35 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 225 402 4.7E-38 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 SUPERFAMILY SSF46589 1 115 7.32E-28 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 PRINTS PR00981 Seryl-tRNA synthetase signature 318 331 5.0E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 PRINTS PR00981 Seryl-tRNA synthetase signature 266 278 5.0E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 PRINTS PR00981 Seryl-tRNA synthetase signature 353 369 5.0E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 PRINTS PR00981 Seryl-tRNA synthetase signature 278 291 5.0E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 PRINTS PR00981 Seryl-tRNA synthetase signature 335 351 5.0E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 Gene3D G3DSA:1.10.287.40 1 107 3.1E-27 T 12-10-2018 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 SUPERFAMILY SSF55681 119 424 6.97E-104 T 12-10-2018 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 424 42.815 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 110 1.5E-30 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 PIRSF PIRSF001529 1 426 2.0E-184 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 Gene3D G3DSA:3.30.930.10 108 426 7.4E-126 T 12-10-2018 NPD12_147 fe21e8799d6c3ec73a016426f4c79942 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 419 2.5E-173 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 SUPERFAMILY SSF50104 2 113 7.22E-46 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 Gene3D G3DSA:2.30.30.790 5 114 1.3E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 30.767 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 5.3E-48 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 2.1E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 2.1E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 2.1E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 Pfam PF01245 Ribosomal protein L19 4 113 1.3E-48 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2492 0f50bda131aaba280e9a68476aa23426 114 PIRSF PIRSF002191 1 114 1.2E-47 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_260 38ff72126a18d876038ecfece1da2a34 248 Pfam PF00731 AIR carboxylase 121 245 3.5E-16 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 NPD12_260 38ff72126a18d876038ecfece1da2a34 248 SMART SM01001 119 248 6.3E-38 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 NPD12_260 38ff72126a18d876038ecfece1da2a34 248 Gene3D G3DSA:3.40.50.7700 120 248 9.9E-36 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 NPD12_260 38ff72126a18d876038ecfece1da2a34 248 SUPERFAMILY SSF52255 119 247 7.98E-30 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 PIRSF PIRSF005243 1 399 8.2E-121 T 12-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 Pfam PF00258 Flavodoxin 257 348 1.5E-6 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 SUPERFAMILY SSF52218 252 398 4.37E-23 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 ProSitePatterns PS00201 Flavodoxin signature. 257 273 - T 12-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 Gene3D G3DSA:3.40.50.360 249 398 4.6E-27 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 Pfam PF00753 Metallo-beta-lactamase superfamily 35 171 2.1E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 Gene3D G3DSA:3.60.15.10 2 247 2.1E-91 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 SUPERFAMILY SSF56281 5 291 9.38E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2873 0d8e7f57acdc4468d61af223dd343fe6 399 SMART SM00849 35 227 2.2E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_800 f205df1084e301416696beb2ce3e5569 241 SUPERFAMILY SSF46689 136 182 7.77E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_800 f205df1084e301416696beb2ce3e5569 241 Pfam PF12833 Helix-turn-helix domain 154 232 3.0E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_800 f205df1084e301416696beb2ce3e5569 241 Gene3D G3DSA:2.60.120.10 13 86 4.3E-5 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_800 f205df1084e301416696beb2ce3e5569 241 Gene3D G3DSA:1.10.10.60 182 238 4.2E-15 T 12-10-2018 NPD12_800 f205df1084e301416696beb2ce3e5569 241 Gene3D G3DSA:1.10.10.60 131 181 1.7E-12 T 12-10-2018 NPD12_800 f205df1084e301416696beb2ce3e5569 241 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 185 227 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_800 f205df1084e301416696beb2ce3e5569 241 SUPERFAMILY SSF46689 184 234 7.62E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_800 f205df1084e301416696beb2ce3e5569 241 Pfam PF02311 AraC-like ligand binding domain 9 66 7.0E-6 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 NPD12_800 f205df1084e301416696beb2ce3e5569 241 SMART SM00342 148 231 7.7E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_800 f205df1084e301416696beb2ce3e5569 241 SUPERFAMILY SSF51215 13 70 4.58E-8 T 12-10-2018 IPR037923 Transcription regulator HTH-like NPD12_2205 252e85685d356199a0cd94cce41614b7 353 Pfam PF00535 Glycosyl transferase family 2 65 172 8.7E-9 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_2205 252e85685d356199a0cd94cce41614b7 353 Gene3D G3DSA:3.90.550.10 32 253 8.0E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2205 252e85685d356199a0cd94cce41614b7 353 SUPERFAMILY SSF53448 57 260 7.97E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2004 844aa4443c341be45f735c8c0dc566b8 292 Pfam PF03747 ADP-ribosylglycohydrolase 9 269 4.0E-50 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 NPD12_2004 844aa4443c341be45f735c8c0dc566b8 292 SUPERFAMILY SSF101478 2 289 3.27E-62 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily NPD12_2004 844aa4443c341be45f735c8c0dc566b8 292 Gene3D G3DSA:1.10.4080.10 1 290 6.4E-73 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily NPD12_866 ef59a211c062379440b1142e48334cab 249 PIRSF PIRSF000363 1 249 1.1E-101 T 12-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 NPD12_866 ef59a211c062379440b1142e48334cab 249 ProSitePatterns PS00692 NifH/frxC family signature 2. 122 135 - T 12-10-2018 IPR030655 NifH/chlL conserved site NPD12_866 ef59a211c062379440b1142e48334cab 249 Gene3D G3DSA:3.40.50.300 1 247 2.3E-59 T 12-10-2018 NPD12_866 ef59a211c062379440b1142e48334cab 249 SUPERFAMILY SSF52540 2 246 7.36E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_866 ef59a211c062379440b1142e48334cab 249 ProSitePatterns PS00746 NifH/frxC family signature 1. 83 95 - T 12-10-2018 IPR030655 NifH/chlL conserved site NPD12_866 ef59a211c062379440b1142e48334cab 249 PRINTS PR00091 Nitrogenase component II signature 29 44 5.8E-34 T 12-10-2018 NPD12_866 ef59a211c062379440b1142e48334cab 249 PRINTS PR00091 Nitrogenase component II signature 121 136 5.8E-34 T 12-10-2018 NPD12_866 ef59a211c062379440b1142e48334cab 249 PRINTS PR00091 Nitrogenase component II signature 7 20 5.8E-34 T 12-10-2018 NPD12_866 ef59a211c062379440b1142e48334cab 249 PRINTS PR00091 Nitrogenase component II signature 81 95 5.8E-34 T 12-10-2018 NPD12_866 ef59a211c062379440b1142e48334cab 249 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 2 246 8.6E-97 T 12-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 NPD12_2565 1ff69a56f0ead6821ab2d841cdd1332f 493 SUPERFAMILY SSF52540 18 252 2.43E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2565 1ff69a56f0ead6821ab2d841cdd1332f 493 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 493 8.2E-260 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 NPD12_2565 1ff69a56f0ead6821ab2d841cdd1332f 493 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 493 1.8E-230 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 NPD12_2565 1ff69a56f0ead6821ab2d841cdd1332f 493 Gene3D G3DSA:3.40.50.300 10 244 3.3E-10 T 12-10-2018 NPD12_2565 1ff69a56f0ead6821ab2d841cdd1332f 493 PIRSF PIRSF007466 1 493 1.7E-238 T 12-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 NPD12_2049 d3d6fed9a2a84e9d8d03aef85f02aea8 290 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 94 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site NPD12_2049 d3d6fed9a2a84e9d8d03aef85f02aea8 290 SUPERFAMILY SSF48576 4 273 8.28E-84 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily NPD12_2049 d3d6fed9a2a84e9d8d03aef85f02aea8 290 Pfam PF00348 Polyprenyl synthetase 27 281 2.9E-59 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 NPD12_2049 d3d6fed9a2a84e9d8d03aef85f02aea8 290 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 209 221 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site NPD12_2049 d3d6fed9a2a84e9d8d03aef85f02aea8 290 Gene3D G3DSA:1.10.600.10 2 290 4.5E-105 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 Gene3D G3DSA:3.40.50.300 2 167 1.3E-49 T 12-10-2018 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 Hamap MF_00109 Shikimate kinase [aroK]. 1 165 24.204 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 Pfam PF01202 Shikimate kinase 12 155 7.1E-41 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 PRINTS PR01100 Shikimate kinase family signature 28 41 8.7E-22 T 12-10-2018 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 PRINTS PR01100 Shikimate kinase family signature 74 83 8.7E-22 T 12-10-2018 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 PRINTS PR01100 Shikimate kinase family signature 56 64 8.7E-22 T 12-10-2018 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 PRINTS PR01100 Shikimate kinase family signature 4 19 8.7E-22 T 12-10-2018 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 PRINTS PR01100 Shikimate kinase family signature 95 112 8.7E-22 T 12-10-2018 NPD12_2065 96fdff0fc535bdbc5a5a2cc782759ba0 170 SUPERFAMILY SSF52540 3 164 9.77E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 Gene3D G3DSA:1.10.150.20 574 584 3.7E-6 T 12-10-2018 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 PRINTS PR00868 DNA-polymerase family A (pol I) signature 601 614 6.4E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 PRINTS PR00868 DNA-polymerase family A (pol I) signature 387 410 6.4E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 Gene3D G3DSA:3.30.70.370 368 395 6.1E-19 T 12-10-2018 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 Gene3D G3DSA:1.10.150.20 396 504 6.1E-19 T 12-10-2018 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 Gene3D G3DSA:3.30.70.370 585 634 3.7E-6 T 12-10-2018 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 SMART SM00482 373 618 4.2E-24 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 Pfam PF00476 DNA polymerase family A 228 635 4.8E-28 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3065 7e397493cbfcac05e272d3d19dd23b7a 653 SUPERFAMILY SSF56672 195 652 7.12E-81 T 12-10-2018 NPD12_1355 476b11a1da494510891646e996d51801 365 SUPERFAMILY SSF53613 61 360 8.57E-60 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1355 476b11a1da494510891646e996d51801 365 Pfam PF00294 pfkB family carbohydrate kinase 60 348 6.2E-46 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB NPD12_1355 476b11a1da494510891646e996d51801 365 SUPERFAMILY SSF46785 1 54 6.59E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1355 476b11a1da494510891646e996d51801 365 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 47 1.9E-10 T 12-10-2018 NPD12_1355 476b11a1da494510891646e996d51801 365 Gene3D G3DSA:3.40.1190.20 54 364 1.4E-76 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1355 476b11a1da494510891646e996d51801 365 Gene3D G3DSA:1.10.10.10 1 50 1.7E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 SUPERFAMILY SSF55136 123 295 1.83E-18 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 SMART SM00871 123 293 2.3E-31 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 Gene3D G3DSA:1.10.10.60 2 54 1.9E-15 T 12-10-2018 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 87 103 9.7E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 72 87 9.7E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 99 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 Pfam PF14526 Integron-associated effector binding protein 127 292 1.3E-22 T 12-10-2018 IPR029441 Integron-associated effector binding protein NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 Gene3D G3DSA:1.10.10.60 55 108 1.3E-10 T 12-10-2018 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 Pfam PF12833 Helix-turn-helix domain 27 103 2.3E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 Gene3D G3DSA:3.20.80.10 123 295 3.0E-38 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 SUPERFAMILY SSF46689 57 105 4.93E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 SUPERFAMILY SSF46689 5 55 3.23E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_780 070e7684b35d121dc14e4f6f360a6bd4 295 SMART SM00342 21 103 8.2E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2559 51ff59a5d519e814f1daa5d4d21bfe53 395 Gene3D G3DSA:3.40.50.1950 1 183 2.8E-61 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 NPD12_2559 51ff59a5d519e814f1daa5d4d21bfe53 395 Pfam PF02441 Flavoprotein 6 172 9.7E-47 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 NPD12_2559 51ff59a5d519e814f1daa5d4d21bfe53 395 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 366 9.9E-70 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 NPD12_2559 51ff59a5d519e814f1daa5d4d21bfe53 395 SUPERFAMILY SSF52507 2 175 9.16E-61 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 NPD12_2559 51ff59a5d519e814f1daa5d4d21bfe53 395 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 391 6.0E-143 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 NPD12_2559 51ff59a5d519e814f1daa5d4d21bfe53 395 Gene3D G3DSA:3.40.50.10300 184 395 2.9E-78 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 NPD12_2559 51ff59a5d519e814f1daa5d4d21bfe53 395 SUPERFAMILY SSF102645 182 393 2.35E-72 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 519 871 1.0E-92 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Gene3D G3DSA:3.50.30.10 384 510 6.8E-80 T 12-10-2018 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Gene3D G3DSA:3.30.470.20 245 342 2.5E-44 T 12-10-2018 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 SUPERFAMILY SSF52009 381 507 1.01E-37 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 298 1.3E-50 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 304 357 4.0E-12 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 SUPERFAMILY SSF56059 3 380 9.77E-151 T 12-10-2018 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Gene3D G3DSA:1.20.80.30 112 199 3.8E-109 T 12-10-2018 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 762 780 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 451 462 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Pfam PF00391 PEP-utilising enzyme, mobile domain 423 504 1.1E-28 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Gene3D G3DSA:1.10.189.10 346 530 6.8E-80 T 12-10-2018 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 SUPERFAMILY SSF51621 513 873 1.8E-132 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 872 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Gene3D G3DSA:3.20.20.60 533 875 1.6E-155 T 12-10-2018 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 PIRSF PIRSF000853 3 877 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 NPD12_2990 5a91dbd0697797bc920fa03c3d8a8a09 877 Gene3D G3DSA:3.30.1490.20 12 244 3.8E-109 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 NPD12_106 7b64796cd5658b433dcf938bd7840960 148 Hamap MF_00984 Single-stranded DNA-binding protein. 1 106 34.547 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 NPD12_106 7b64796cd5658b433dcf938bd7840960 148 Pfam PF00436 Single-strand binding protein family 1 102 3.7E-36 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 NPD12_106 7b64796cd5658b433dcf938bd7840960 148 Gene3D G3DSA:2.40.50.140 1 111 1.6E-42 T 12-10-2018 NPD12_106 7b64796cd5658b433dcf938bd7840960 148 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 125 1.3E-36 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 NPD12_106 7b64796cd5658b433dcf938bd7840960 148 PIRSF PIRSF002070 1 147 1.3E-38 T 12-10-2018 NPD12_106 7b64796cd5658b433dcf938bd7840960 148 SUPERFAMILY SSF50249 1 148 5.14E-48 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 Gene3D G3DSA:2.30.42.10 111 197 1.1E-90 T 12-10-2018 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 Gene3D G3DSA:3.30.750.44 63 346 1.1E-90 T 12-10-2018 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 SMART SM00245 183 371 8.9E-71 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 SUPERFAMILY SSF50156 102 182 4.3E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 Gene3D G3DSA:3.90.226.10 198 368 1.1E-90 T 12-10-2018 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 SMART SM00228 111 182 6.8E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 Pfam PF13180 PDZ domain 113 183 2.3E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 SUPERFAMILY SSF52096 47 388 1.34E-76 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 62 379 1.1E-108 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 NPD12_3544 110082a66d764a9976490ec2c95d9a7b 401 Pfam PF03572 Peptidase family S41 208 370 2.0E-51 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 NPD12_2538 f0a011dc5930ee09eaced2c915276fd2 409 SUPERFAMILY SSF52374 3 225 2.63E-17 T 12-10-2018 NPD12_2538 f0a011dc5930ee09eaced2c915276fd2 409 Gene3D G3DSA:3.40.50.620 1 188 3.2E-39 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2538 f0a011dc5930ee09eaced2c915276fd2 409 Pfam PF05636 HIGH Nucleotidyl Transferase 1 390 3.9E-134 T 12-10-2018 IPR008513 Uncharacterised protein family UPF0348 NPD12_2538 f0a011dc5930ee09eaced2c915276fd2 409 Hamap MF_01539 UPF0348 protein . 2 403 35.13 T 12-10-2018 IPR008513 Uncharacterised protein family UPF0348 NPD12_514 f414ac198889d6aa188d882511da411d 175 SUPERFAMILY SSF48317 4 172 1.31E-42 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily NPD12_514 f414ac198889d6aa188d882511da411d 175 Pfam PF01569 PAP2 superfamily 62 173 1.4E-27 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase NPD12_514 f414ac198889d6aa188d882511da411d 175 Gene3D G3DSA:1.20.144.10 6 90 1.8E-8 T 12-10-2018 NPD12_514 f414ac198889d6aa188d882511da411d 175 Gene3D G3DSA:1.20.144.10 91 174 6.3E-22 T 12-10-2018 NPD12_514 f414ac198889d6aa188d882511da411d 175 SMART SM00014 57 167 3.0E-25 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase NPD12_75 0366633927eb0d6771a840ce77b8b90d 352 Gene3D G3DSA:3.20.20.70 10 352 4.8E-75 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_75 0366633927eb0d6771a840ce77b8b90d 352 Pfam PF03060 Nitronate monooxygenase 7 350 1.0E-61 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 NPD12_75 0366633927eb0d6771a840ce77b8b90d 352 SUPERFAMILY SSF51412 10 348 1.47E-52 T 12-10-2018 NPD12_1120 3488d0297614e280c0f7444155fe5301 150 Pfam PF04229 GrpB protein 2 146 1.1E-44 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase NPD12_1120 3488d0297614e280c0f7444155fe5301 150 SUPERFAMILY SSF81301 3 149 2.58E-47 T 12-10-2018 NPD12_1120 3488d0297614e280c0f7444155fe5301 150 Gene3D G3DSA:3.30.460.10 1 150 2.8E-47 T 12-10-2018 NPD12_2687 add5591d097ff74a31b595dc53ed3650 263 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 133 5.2E-43 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G NPD12_2687 add5591d097ff74a31b595dc53ed3650 263 SUPERFAMILY SSF117143 90 223 8.5E-22 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like NPD12_2687 add5591d097ff74a31b595dc53ed3650 263 Pfam PF00460 Flagella basal body rod protein 5 35 3.4E-12 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 NPD12_2687 add5591d097ff74a31b595dc53ed3650 263 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 193 261 8.4E-19 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain NPD12_2687 add5591d097ff74a31b595dc53ed3650 263 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site NPD12_3103 f1336d74e3693de0a25d4e8db2857111 265 PIRSF PIRSF003092 1 265 2.1E-85 T 12-10-2018 IPR025501 ATP binding protein MinD NPD12_3103 f1336d74e3693de0a25d4e8db2857111 265 Gene3D G3DSA:3.40.50.300 1 254 1.9E-65 T 12-10-2018 NPD12_3103 f1336d74e3693de0a25d4e8db2857111 265 SUPERFAMILY SSF52540 1 261 4.83E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3103 f1336d74e3693de0a25d4e8db2857111 265 Pfam PF13614 AAA domain 3 158 1.9E-24 T 12-10-2018 IPR025669 AAA domain NPD12_3103 f1336d74e3693de0a25d4e8db2857111 265 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 262 2.5E-120 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 Gene3D G3DSA:3.40.630.10 4 401 7.3E-182 T 12-10-2018 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 Hamap MF_00550 Peptidase T [pepT]. 1 405 59.358 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 139 178 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 Pfam PF07687 Peptidase dimerisation domain 208 307 2.0E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 SUPERFAMILY SSF55031 210 321 1.15E-39 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 PIRSF PIRSF037215 1 408 5.3E-190 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 Pfam PF01546 Peptidase family M20/M25/M40 140 402 3.8E-10 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 407 7.2E-180 T 12-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 Gene3D G3DSA:3.30.70.360 210 320 7.3E-182 T 12-10-2018 NPD12_608 f2dcef4b5af85d43a0b43a7e20a22fe3 408 SUPERFAMILY SSF53187 1 407 7.01E-80 T 12-10-2018 NPD12_3425 5b9e04e81d7fd4b9d2eb962eb789f5bb 249 Pfam PF01171 PP-loop family 31 211 8.8E-20 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 NPD12_3425 5b9e04e81d7fd4b9d2eb962eb789f5bb 249 PIRSF PIRSF004976 2 249 3.1E-59 T 12-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 NPD12_3425 5b9e04e81d7fd4b9d2eb962eb789f5bb 249 SUPERFAMILY SSF52402 8 222 6.4E-48 T 12-10-2018 NPD12_3425 5b9e04e81d7fd4b9d2eb962eb789f5bb 249 Gene3D G3DSA:3.40.50.620 3 247 5.2E-52 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SUPERFAMILY SSF82185 38 130 1.26E-27 T 12-10-2018 NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SUPERFAMILY SSF82185 103 186 1.18E-23 T 12-10-2018 NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Pfam PF02493 MORN repeat 132 150 5.9E-5 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Pfam PF02493 MORN repeat 40 61 6.9E-6 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Pfam PF02493 MORN repeat 155 175 2.8E-6 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Pfam PF02493 MORN repeat 63 83 1.1E-6 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Pfam PF02493 MORN repeat 109 131 1.7E-6 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Pfam PF02493 MORN repeat 86 106 1.3E-8 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Gene3D G3DSA:2.20.110.10 41 114 3.7E-18 T 12-10-2018 NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 Gene3D G3DSA:2.20.110.10 115 189 1.8E-17 T 12-10-2018 NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SMART SM00698 61 82 0.0014 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SMART SM00698 84 105 2.9E-6 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SMART SM00698 107 128 0.024 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SMART SM00698 153 174 3.7E-6 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SMART SM00698 130 151 0.059 T 12-10-2018 IPR003409 MORN motif NPD12_1749 51c35e694e76164b2a8f7f736f924ebc 189 SMART SM00698 38 59 9.1E-4 T 12-10-2018 IPR003409 MORN motif NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 SMART SM00475 2 263 1.8E-129 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 SMART SM00482 632 839 8.6E-115 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Pfam PF00476 DNA polymerase family A 500 873 1.5E-153 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Pfam PF01612 3'-5' exonuclease 313 440 3.6E-5 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Gene3D G3DSA:1.20.1060.10 491 603 1.6E-39 T 12-10-2018 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 ProSitePatterns PS00447 DNA polymerase family A signature. 701 720 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 264 1.8E-34 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Gene3D G3DSA:1.10.150.20 175 248 3.6E-103 T 12-10-2018 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Gene3D G3DSA:3.30.420.10 300 489 1.9E-22 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 SUPERFAMILY SSF56672 470 875 3.11E-151 T 12-10-2018 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 SMART SM00279 174 209 4.6E-17 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 SUPERFAMILY SSF88723 3 171 8.97E-56 T 12-10-2018 IPR029060 PIN-like domain superfamily NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Gene3D G3DSA:3.30.70.370 610 871 1.6E-106 T 12-10-2018 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Gene3D G3DSA:3.40.50.1010 6 280 3.6E-103 T 12-10-2018 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 171 4.8E-53 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 TIGRFAM TIGR00593 pola: DNA polymerase I 6 875 4.7E-303 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 SUPERFAMILY SSF53098 305 467 4.4E-25 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 SUPERFAMILY SSF47807 172 287 4.93E-34 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 601 623 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 835 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 760 771 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 624 639 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 647 670 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 701 726 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 690 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 738 749 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 792 808 1.7E-74 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3119 5446198218bf984e5ae21f046d6e8052 875 Gene3D G3DSA:1.10.150.20 656 799 1.6E-106 T 12-10-2018 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 Gene3D G3DSA:3.30.420.40 139 333 2.6E-146 T 12-10-2018 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 Hamap MF_00542 Probable butyrate kinase [buk]. 1 364 156.064 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 SUPERFAMILY SSF53067 7 174 3.39E-67 T 12-10-2018 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 PIRSF PIRSF036458 4 357 1.4E-153 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 SUPERFAMILY SSF53067 121 347 6.98E-48 T 12-10-2018 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 7 354 4.2E-153 T 12-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 Pfam PF00871 Acetokinase family 6 354 4.3E-64 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 Gene3D G3DSA:3.30.420.40 7 356 2.6E-146 T 12-10-2018 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 PRINTS PR00471 Acetate kinase family signature 7 18 4.3E-19 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 PRINTS PR00471 Acetate kinase family signature 275 288 4.3E-19 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 PRINTS PR00471 Acetate kinase family signature 181 202 4.3E-19 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 PRINTS PR00471 Acetate kinase family signature 298 314 4.3E-19 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_3586 89150a546b1177d5badc9bdf30658bb9 364 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 NPD12_1019 a46d7ddc8e94bb8a6f70f9ca5efa4048 391 Gene3D G3DSA:3.90.1150.10 262 390 3.5E-28 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1019 a46d7ddc8e94bb8a6f70f9ca5efa4048 391 SUPERFAMILY SSF53383 3 388 5.33E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1019 a46d7ddc8e94bb8a6f70f9ca5efa4048 391 Gene3D G3DSA:3.40.640.10 1 260 1.9E-81 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1019 a46d7ddc8e94bb8a6f70f9ca5efa4048 391 PIRSF PIRSF000390 1 390 5.8E-94 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_1019 a46d7ddc8e94bb8a6f70f9ca5efa4048 391 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 382 4.8E-96 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_55 56ed05c592eec26a06f97045c45926bb 414 Pfam PF13439 Glycosyltransferase Family 4 16 210 7.8E-9 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_55 56ed05c592eec26a06f97045c45926bb 414 Pfam PF00534 Glycosyl transferases group 1 214 344 4.0E-24 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_55 56ed05c592eec26a06f97045c45926bb 414 SUPERFAMILY SSF53756 6 343 3.04E-52 T 12-10-2018 NPD12_55 56ed05c592eec26a06f97045c45926bb 414 Gene3D G3DSA:3.40.50.2000 207 345 4.9E-46 T 12-10-2018 NPD12_55 56ed05c592eec26a06f97045c45926bb 414 Gene3D G3DSA:3.40.50.2000 80 206 4.9E-46 T 12-10-2018 NPD12_224 7b54aada29093c2ffe20c6e98d2bb96b 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 154 1.4E-66 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 NPD12_224 7b54aada29093c2ffe20c6e98d2bb96b 158 SUPERFAMILY SSF69765 1 154 4.97E-65 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 NPD12_224 7b54aada29093c2ffe20c6e98d2bb96b 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 NPD12_224 7b54aada29093c2ffe20c6e98d2bb96b 158 Pfam PF02542 YgbB family 1 154 1.3E-65 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 NPD12_224 7b54aada29093c2ffe20c6e98d2bb96b 158 Gene3D G3DSA:3.30.1330.50 1 157 2.4E-66 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 NPD12_224 7b54aada29093c2ffe20c6e98d2bb96b 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 35.512 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 NPD12_2296 0fdf2fc0e80967ae22e7c3683c87749d 246 Gene3D G3DSA:2.20.25.110 137 204 1.9E-29 T 12-10-2018 NPD12_2296 0fdf2fc0e80967ae22e7c3683c87749d 246 Pfam PF13649 Methyltransferase domain 38 129 4.9E-11 T 12-10-2018 NPD12_2296 0fdf2fc0e80967ae22e7c3683c87749d 246 Gene3D G3DSA:3.40.50.150 13 241 1.9E-29 T 12-10-2018 NPD12_2296 0fdf2fc0e80967ae22e7c3683c87749d 246 SUPERFAMILY SSF53335 17 230 1.47E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 SUPERFAMILY SSF53067 105 317 7.78E-46 T 12-10-2018 NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 Pfam PF00814 Glycoprotease family 27 312 1.8E-103 T 12-10-2018 IPR000905 Gcp-like domain NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 4.6E-137 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 337 63.463 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 Gene3D G3DSA:3.30.420.40 7 319 3.3E-127 T 12-10-2018 NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 312 1.9E-111 T 12-10-2018 IPR017861 Kae1/TsaD family NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 Gene3D G3DSA:3.30.420.40 133 299 3.3E-127 T 12-10-2018 NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 135 147 5.5E-46 T 12-10-2018 IPR017861 Kae1/TsaD family NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 5.5E-46 T 12-10-2018 IPR017861 Kae1/TsaD family NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 269 278 5.5E-46 T 12-10-2018 IPR017861 Kae1/TsaD family NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 5.5E-46 T 12-10-2018 IPR017861 Kae1/TsaD family NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 5.5E-46 T 12-10-2018 IPR017861 Kae1/TsaD family NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 5.5E-46 T 12-10-2018 IPR017861 Kae1/TsaD family NPD12_3441 56ecf9a0592fcda2f92d5c365a5bfaae 340 SUPERFAMILY SSF53067 6 125 2.46E-31 T 12-10-2018 NPD12_666 569b43fff9b159e92492005a588a7740 217 Gene3D G3DSA:3.40.50.150 1 216 4.2E-66 T 12-10-2018 NPD12_666 569b43fff9b159e92492005a588a7740 217 SUPERFAMILY SSF53335 27 213 1.33E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_666 569b43fff9b159e92492005a588a7740 217 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 210 9.6E-46 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 NPD12_666 569b43fff9b159e92492005a588a7740 217 Pfam PF02390 Putative methyltransferase 38 210 5.9E-40 T 12-10-2018 NPD12_666 569b43fff9b159e92492005a588a7740 217 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 217 25.327 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 NPD12_3551 52bd6cc93abfb87c0ff2932fe2f4cfc5 117 SUPERFAMILY SSF50118 5 116 1.05E-40 T 12-10-2018 NPD12_3551 52bd6cc93abfb87c0ff2932fe2f4cfc5 117 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 7 113 1.0E-34 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 NPD12_3551 52bd6cc93abfb87c0ff2932fe2f4cfc5 117 Gene3D G3DSA:2.30.30.110 1 117 1.4E-51 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor NPD12_3551 52bd6cc93abfb87c0ff2932fe2f4cfc5 117 PIRSF PIRSF033490 4 116 3.9E-37 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 NPD12_2916 703f108adad1c172f4eed785537cb7d3 619 Gene3D G3DSA:3.40.720.10 241 543 6.7E-76 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 NPD12_2916 703f108adad1c172f4eed785537cb7d3 619 Pfam PF00884 Sulfatase 249 536 1.3E-40 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 NPD12_2916 703f108adad1c172f4eed785537cb7d3 619 SUPERFAMILY SSF53649 248 577 4.42E-66 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 NPD12_2916 703f108adad1c172f4eed785537cb7d3 619 PIRSF PIRSF005091 1 619 2.0E-180 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like NPD12_281 e463acf9a9f2e49f8270feeb7ff1a5f8 413 SUPERFAMILY SSF53756 90 366 2.51E-34 T 12-10-2018 NPD12_281 e463acf9a9f2e49f8270feeb7ff1a5f8 413 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 206 341 1.9E-10 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 NPD12_281 e463acf9a9f2e49f8270feeb7ff1a5f8 413 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 14 180 8.1E-47 T 12-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 NPD12_281 e463acf9a9f2e49f8270feeb7ff1a5f8 413 Gene3D G3DSA:3.40.50.2000 188 354 9.0E-30 T 12-10-2018 NPD12_3175 5b106d6c4e097cd25670dfaae42df2aa 122 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 10 122 1.3E-29 T 12-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane NPD12_3175 5b106d6c4e097cd25670dfaae42df2aa 122 Pfam PF12670 Protein of unknown function (DUF3792) 9 119 1.7E-24 T 12-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 Pfam PF00005 ABC transporter 361 510 2.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 SUPERFAMILY SSF90123 10 325 2.22E-57 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 SUPERFAMILY SSF52540 327 579 3.15E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 Pfam PF00664 ABC transporter transmembrane region 21 291 1.5E-28 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 Gene3D G3DSA:1.20.1560.10 1 324 1.9E-48 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 Gene3D G3DSA:3.40.50.300 328 593 3.1E-83 T 12-10-2018 NPD12_2402 a5bf937cd74476a05e7956baf954b271 599 SMART SM00382 370 556 2.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2281 448714e15eb03d45b410d39972f7a80d 285 Pfam PF01261 Xylose isomerase-like TIM barrel 21 228 1.2E-28 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain NPD12_2281 448714e15eb03d45b410d39972f7a80d 285 Gene3D G3DSA:3.20.20.150 2 273 1.9E-55 T 12-10-2018 NPD12_2281 448714e15eb03d45b410d39972f7a80d 285 SUPERFAMILY SSF51658 3 275 1.17E-52 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily NPD12_414 a55e5e6cbe77a76310085167e0d09f20 170 Gene3D G3DSA:3.40.630.30 4 168 5.4E-28 T 12-10-2018 NPD12_414 a55e5e6cbe77a76310085167e0d09f20 170 Pfam PF13420 Acetyltransferase (GNAT) domain 33 164 2.9E-7 T 12-10-2018 NPD12_414 a55e5e6cbe77a76310085167e0d09f20 170 SUPERFAMILY SSF55729 16 165 1.98E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2885 d7ff222909d9fe9710464c7fd829b89a 162 Pfam PF01799 [2Fe-2S] binding domain 80 149 5.4E-25 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 NPD12_2885 d7ff222909d9fe9710464c7fd829b89a 162 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 62 1.4E-5 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 NPD12_2885 d7ff222909d9fe9710464c7fd829b89a 162 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 46 54 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 NPD12_2885 d7ff222909d9fe9710464c7fd829b89a 162 Gene3D G3DSA:1.10.150.120 83 161 9.0E-26 T 12-10-2018 NPD12_2885 d7ff222909d9fe9710464c7fd829b89a 162 SUPERFAMILY SSF47741 80 155 1.57E-27 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily NPD12_2885 d7ff222909d9fe9710464c7fd829b89a 162 Gene3D G3DSA:3.10.20.30 5 82 1.4E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_2885 d7ff222909d9fe9710464c7fd829b89a 162 SUPERFAMILY SSF54292 10 94 3.41E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 NPD12_1064 b1d77647149c9332d3b57fc07f542f18 317 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 317 20.096 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1064 b1d77647149c9332d3b57fc07f542f18 317 Pfam PF00953 Glycosyl transferase family 4 77 244 6.2E-34 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 NPD12_1064 b1d77647149c9332d3b57fc07f542f18 317 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 316 6.9E-86 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1064 b1d77647149c9332d3b57fc07f542f18 317 ProSitePatterns PS01348 MraY family signature 2. 164 175 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_3582 679e428c023555af06d2af82696da412 69 SUPERFAMILY SSF54862 3 68 2.71E-14 T 12-10-2018 NPD12_3582 679e428c023555af06d2af82696da412 69 Gene3D G3DSA:3.30.70.20 2 69 1.1E-12 T 12-10-2018 NPD12_3582 679e428c023555af06d2af82696da412 69 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 50 61 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_3582 679e428c023555af06d2af82696da412 69 Pfam PF12838 4Fe-4S dicluster domain 10 61 6.5E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_657 4bd050c0ddfbc452770c50c1f1330b66 212 Pfam PF02517 CAAX protease self-immunity 118 206 5.2E-11 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 9.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 9.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 SMART SM00342 21 104 1.5E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 Pfam PF06445 GyrI-like small molecule binding domain 133 201 5.5E-6 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 Pfam PF12833 Helix-turn-helix domain 28 105 3.1E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 Gene3D G3DSA:1.10.10.60 2 57 1.0E-15 T 12-10-2018 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 SUPERFAMILY SSF46689 5 55 2.6E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 Gene3D G3DSA:3.20.80.10 133 221 1.5E-6 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 Gene3D G3DSA:1.10.10.60 58 112 3.5E-17 T 12-10-2018 NPD12_1069 47fe70dd915c6943fd446f53bf252d7f 248 SUPERFAMILY SSF46689 57 108 6.27E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2770 45327e0d5e69cdd46dc54a86801126ae 72 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 69 1.0E-24 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 NPD12_2770 45327e0d5e69cdd46dc54a86801126ae 72 Gene3D G3DSA:3.30.70.1680 1 62 3.8E-26 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 NPD12_2770 45327e0d5e69cdd46dc54a86801126ae 72 SUPERFAMILY SSF117130 1 55 1.83E-18 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 NPD12_2770 45327e0d5e69cdd46dc54a86801126ae 72 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 72 17.643 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 NPD12_2770 45327e0d5e69cdd46dc54a86801126ae 72 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 3.0E-14 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 NPD12_2770 45327e0d5e69cdd46dc54a86801126ae 72 Pfam PF02599 Global regulator protein family 1 53 1.7E-24 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 NPD12_2552 8d87a62a27d76e0e659c46aa8e71d95a 249 Pfam PF13672 Protein phosphatase 2C 13 203 6.7E-16 T 12-10-2018 NPD12_2552 8d87a62a27d76e0e659c46aa8e71d95a 249 SMART SM00332 2 237 1.3E-17 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_2552 8d87a62a27d76e0e659c46aa8e71d95a 249 SMART SM00331 6 239 3.2E-37 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_2552 8d87a62a27d76e0e659c46aa8e71d95a 249 Gene3D G3DSA:3.60.40.10 2 240 1.2E-65 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_2552 8d87a62a27d76e0e659c46aa8e71d95a 249 SUPERFAMILY SSF81606 3 236 2.75E-61 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 527 3.2E-40 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Pfam PF02824 TGS domain 2 61 1.1E-10 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 SUPERFAMILY SSF52954 527 632 1.15E-34 T 12-10-2018 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Gene3D G3DSA:3.30.980.10 70 221 1.0E-64 T 12-10-2018 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 3.3E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 518 3.3E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 3.3E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 532 544 3.3E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 462 490 3.3E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Gene3D G3DSA:3.30.930.10 222 529 6.9E-131 T 12-10-2018 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 SUPERFAMILY SSF55186 64 240 2.22E-64 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 632 35.13 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Pfam PF03129 Anticodon binding domain 539 628 2.2E-24 T 12-10-2018 IPR004154 Anticodon-binding NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Gene3D G3DSA:3.30.54.20 130 186 1.0E-64 T 12-10-2018 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 SUPERFAMILY SSF81271 2 62 4.8E-15 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Gene3D G3DSA:3.40.50.800 530 635 1.4E-35 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Gene3D G3DSA:3.10.20.30 1 64 1.4E-21 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 SUPERFAMILY SSF55681 242 524 8.3E-102 T 12-10-2018 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 SMART SM00863 169 218 6.9E-25 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 629 1.2E-230 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 NPD12_3246 0ef5d50a4e85863b8d0d93576e83d0fe 635 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.1E-15 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 NPD12_3176 968d070abe783d219baf24187490c479 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 6 26 5.2E-8 T 12-10-2018 IPR003849 Preprotein translocase YajC NPD12_3176 968d070abe783d219baf24187490c479 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 44 62 5.2E-8 T 12-10-2018 IPR003849 Preprotein translocase YajC NPD12_3176 968d070abe783d219baf24187490c479 111 SMART SM01323 4 87 1.2E-27 T 12-10-2018 IPR003849 Preprotein translocase YajC NPD12_3176 968d070abe783d219baf24187490c479 111 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 10 87 3.2E-18 T 12-10-2018 IPR003849 Preprotein translocase YajC NPD12_3176 968d070abe783d219baf24187490c479 111 Pfam PF02699 Preprotein translocase subunit 10 83 1.9E-23 T 12-10-2018 IPR003849 Preprotein translocase YajC NPD12_1790 28b5db5054fafaa410a553966c4b6f35 240 SUPERFAMILY SSF55136 90 240 6.28E-22 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_1790 28b5db5054fafaa410a553966c4b6f35 240 Gene3D G3DSA:3.20.80.10 86 240 2.8E-38 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_1790 28b5db5054fafaa410a553966c4b6f35 240 SMART SM00871 87 240 5.3E-32 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_1790 28b5db5054fafaa410a553966c4b6f35 240 Pfam PF14526 Integron-associated effector binding protein 91 239 1.0E-26 T 12-10-2018 IPR029441 Integron-associated effector binding protein NPD12_1790 28b5db5054fafaa410a553966c4b6f35 240 Pfam PF12674 Putative zinc ribbon domain 5 83 1.9E-27 T 12-10-2018 IPR025868 Putative zinc ribbon domain NPD12_3115 d27b8e0f8c4f81918dd82dc06362b1dd 145 PIRSF PIRSF025624 1 145 4.0E-58 T 12-10-2018 IPR008310 UPF0735 ACT domain-containing protein NPD12_3115 d27b8e0f8c4f81918dd82dc06362b1dd 145 Hamap MF_00707 UPF0735 ACT domain-containing protein . 1 145 32.006 T 12-10-2018 IPR008310 UPF0735 ACT domain-containing protein NPD12_3115 d27b8e0f8c4f81918dd82dc06362b1dd 145 SUPERFAMILY SSF55021 68 140 5.35E-9 T 12-10-2018 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 SUPERFAMILY SSF46565 1 106 6.15E-37 T 12-10-2018 IPR036869 Chaperone J-domain superfamily NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 SUPERFAMILY SSF49493 118 265 8.5E-17 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 SUPERFAMILY SSF57938 138 219 3.53E-19 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 12-10-2018 IPR018253 DnaJ domain, conserved site NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Gene3D G3DSA:2.10.230.10 151 215 1.8E-36 T 12-10-2018 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 SUPERFAMILY SSF49493 267 352 1.44E-23 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 358 4.2E-143 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Pfam PF00684 DnaJ central domain 151 215 2.0E-14 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Pfam PF01556 DnaJ C terminal domain 124 341 9.1E-45 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Gene3D G3DSA:2.60.260.20 262 370 2.3E-29 T 12-10-2018 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Gene3D G3DSA:2.60.260.20 121 257 1.8E-36 T 12-10-2018 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 378 40.846 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Pfam PF00226 DnaJ domain 5 67 4.3E-29 T 12-10-2018 IPR001623 DnaJ domain NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 SMART SM00271 4 62 3.3E-34 T 12-10-2018 IPR001623 DnaJ domain NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 PRINTS PR00625 DnaJ domain signature 62 81 2.5E-29 T 12-10-2018 IPR001623 DnaJ domain NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 PRINTS PR00625 DnaJ domain signature 25 40 2.5E-29 T 12-10-2018 IPR001623 DnaJ domain NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 PRINTS PR00625 DnaJ domain signature 42 62 2.5E-29 T 12-10-2018 IPR001623 DnaJ domain NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 PRINTS PR00625 DnaJ domain signature 7 25 2.5E-29 T 12-10-2018 IPR001623 DnaJ domain NPD12_3007 42660eab3ca5c0eddb28478fe21770a3 381 Gene3D G3DSA:1.10.287.110 2 117 8.0E-40 T 12-10-2018 IPR036869 Chaperone J-domain superfamily NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 Pfam PF04055 Radical SAM superfamily 152 322 3.6E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 Gene3D G3DSA:3.80.30.20 145 378 4.9E-86 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 5 437 4.6E-149 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 SUPERFAMILY SSF102114 142 369 2.62E-57 T 12-10-2018 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 Gene3D G3DSA:2.40.50.140 379 445 7.4E-19 T 12-10-2018 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 SMART SM00729 146 364 3.7E-53 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 Gene3D G3DSA:3.40.50.12160 4 138 9.5E-39 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 437 1.2E-132 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 Pfam PF00919 Uncharacterized protein family UPF0004 5 103 9.0E-26 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 NPD12_2454 c93c9d809958fc45ceee78ec1216845a 445 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 4 439 66.144 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 9.5E-82 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 3.0E-37 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 SUPERFAMILY SSF52440 1 111 2.16E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 SMART SM00878 336 442 9.2E-60 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 SUPERFAMILY SSF51246 331 445 8.37E-43 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 SUPERFAMILY SSF56059 83 349 5.72E-74 T 12-10-2018 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 3.7E-45 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 2 446 3.4E-226 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 NPD12_65 0d1fadec791d0897e84a0e2a3ed85585 448 Gene3D G3DSA:3.30.470.130 1 447 3.4E-193 T 12-10-2018 NPD12_1956 e1e4bb642a4d885758c8b1a35daaa448 352 Gene3D G3DSA:3.30.200.20 4 108 7.8E-19 T 12-10-2018 NPD12_1956 e1e4bb642a4d885758c8b1a35daaa448 352 Gene3D G3DSA:3.90.1200.10 109 345 1.1E-67 T 12-10-2018 NPD12_1956 e1e4bb642a4d885758c8b1a35daaa448 352 SUPERFAMILY SSF56112 20 347 1.7E-44 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_1956 e1e4bb642a4d885758c8b1a35daaa448 352 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 32 343 2.0E-94 T 12-10-2018 IPR014255 Spore coat protein CotS NPD12_1141 50a508e54de2c68141f49c3129b3b6f0 229 SUPERFAMILY SSF46785 149 226 7.59E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1141 50a508e54de2c68141f49c3129b3b6f0 229 SMART SM00419 170 218 1.6E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_1141 50a508e54de2c68141f49c3129b3b6f0 229 SMART SM00100 14 131 9.6E-14 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_1141 50a508e54de2c68141f49c3129b3b6f0 229 SUPERFAMILY SSF51206 9 143 3.54E-30 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like NPD12_1141 50a508e54de2c68141f49c3129b3b6f0 229 Gene3D G3DSA:2.60.120.1460 18 226 1.6E-50 T 12-10-2018 NPD12_1141 50a508e54de2c68141f49c3129b3b6f0 229 Pfam PF00027 Cyclic nucleotide-binding domain 34 116 9.1E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_1141 50a508e54de2c68141f49c3129b3b6f0 229 Pfam PF13545 Crp-like helix-turn-helix domain 152 224 2.3E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 Gene3D G3DSA:3.90.45.10 1 147 4.8E-55 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 PRINTS PR01576 Peptide deformylase signature 86 97 3.2E-35 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 PRINTS PR01576 Peptide deformylase signature 98 116 3.2E-35 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 PRINTS PR01576 Peptide deformylase signature 117 146 3.2E-35 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 PRINTS PR01576 Peptide deformylase signature 33 62 3.2E-35 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 SUPERFAMILY SSF56420 2 145 1.23E-54 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 144 3.0E-48 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 Pfam PF01327 Polypeptide deformylase 4 144 2.9E-49 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 PIRSF PIRSF004749 1 147 2.5E-48 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2557 7184e403e5639d9d6af5b330ac951ed5 147 Hamap MF_00163 Peptide deformylase [def]. 2 147 28.071 T 12-10-2018 IPR023635 Peptide deformylase NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 Gene3D G3DSA:4.10.950.10 197 276 4.3E-33 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 6.8E-55 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 2.4E-35 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.6E-134 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 SUPERFAMILY SSF50104 126 273 3.97E-60 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 SUPERFAMILY SSF50249 2 125 4.46E-51 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 PIRSF PIRSF002158 7 276 1.3E-98 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 SMART SM01382 124 253 1.2E-89 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 SMART SM01383 42 118 4.5E-48 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 Gene3D G3DSA:2.40.50.140 1 114 2.2E-47 T 12-10-2018 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 Gene3D G3DSA:2.30.30.30 118 196 1.3E-34 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 47.361 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 NPD12_3636 36b747db65766e85bd4cb77accff9ccb 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_173 238941abb571c200a7db002e411edf4e 162 Pfam PF00293 NUDIX domain 43 148 1.6E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 NPD12_173 238941abb571c200a7db002e411edf4e 162 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 NPD12_173 238941abb571c200a7db002e411edf4e 162 SUPERFAMILY SSF55811 4 160 3.93E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 NPD12_173 238941abb571c200a7db002e411edf4e 162 Gene3D G3DSA:3.90.79.10 38 162 6.5E-23 T 12-10-2018 NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 Gene3D G3DSA:3.30.930.10 19 439 9.9E-137 T 12-10-2018 NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 SUPERFAMILY SSF55826 231 351 3.92E-25 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 Gene3D G3DSA:3.90.960.10 218 363 9.9E-137 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 SUPERFAMILY SSF55681 12 452 6.5E-17 T 12-10-2018 NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 Pfam PF03129 Anticodon binding domain 451 540 1.8E-15 T 12-10-2018 IPR004154 Anticodon-binding NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 SUPERFAMILY SSF52954 438 542 2.13E-25 T 12-10-2018 NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 Gene3D G3DSA:3.40.50.800 440 532 9.9E-137 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily NPD12_3665 bb3e4136dc2527e3cc99600bed12f731 545 Pfam PF04073 Aminoacyl-tRNA editing domain 236 350 1.7E-24 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 SMART SM00382 28 232 1.5E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 SMART SM00382 343 513 2.4E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 Pfam PF16326 ABC transporter C-terminal domain 561 626 4.3E-11 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 Pfam PF00005 ABC transporter 20 187 4.8E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 Gene3D G3DSA:3.40.50.300 282 555 2.7E-59 T 12-10-2018 NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 SUPERFAMILY SSF52540 5 233 9.91E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 SUPERFAMILY SSF52540 311 523 3.7E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 Pfam PF12848 ABC transporter 226 294 2.6E-12 T 12-10-2018 IPR032781 ABC-transporter extension domain NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 Pfam PF00005 ABC transporter 336 469 9.2E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1258 8812b4407d4dbf78df27ba85e523614e 639 Gene3D G3DSA:3.40.50.300 1 281 7.7E-67 T 12-10-2018 NPD12_2855 ddbd7fad2c6ca74c2822fa981d97e49c 132 Pfam PF16760 Starch/carbohydrate-binding module (family 53) 41 126 1.5E-16 T 12-10-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 NPD12_2855 ddbd7fad2c6ca74c2822fa981d97e49c 132 SMART SM01066 38 127 2.1E-30 T 12-10-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 NPD12_2855 ddbd7fad2c6ca74c2822fa981d97e49c 132 Gene3D G3DSA:2.60.40.10 35 132 7.4E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 SUPERFAMILY SSF54862 8 106 1.82E-20 T 12-10-2018 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 Pfam PF00037 4Fe-4S binding domain 50 71 2.7E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 Pfam PF04055 Radical SAM superfamily 92 240 4.8E-24 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 Gene3D G3DSA:3.20.20.70 3 56 2.6E-17 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 Pfam PF13353 4Fe-4S single cluster domain 84 172 6.9E-8 T 12-10-2018 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 SUPERFAMILY SSF102114 93 269 4.32E-25 T 12-10-2018 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 Gene3D G3DSA:3.80.30.10 123 300 3.8E-67 T 12-10-2018 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 PIRSF PIRSF000371 2 300 4.0E-109 T 12-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 12-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 Gene3D G3DSA:3.30.70.20 57 98 4.4E-9 T 12-10-2018 NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 55 66 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_3295 de8d6e9332984b86083d0ee06423e453 301 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 6 293 8.6E-115 T 12-10-2018 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 Gene3D G3DSA:1.10.10.60 237 288 1.4E-16 T 12-10-2018 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 293 335 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 SUPERFAMILY SSF46689 241 289 7.17E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 308 323 8.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 323 339 8.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 Pfam PF10114 Sensory domain found in PocR 11 176 4.3E-49 T 12-10-2018 IPR018771 PocR domain NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 SUPERFAMILY SSF46689 293 341 2.24E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 Gene3D G3DSA:1.10.10.60 289 345 7.9E-18 T 12-10-2018 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 Pfam PF12833 Helix-turn-helix domain 262 340 2.5E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1166 83c6169fb7a448b8c39788e49854ca1a 345 SMART SM00342 256 339 2.0E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2135 74915c68188196a05521b530d429a56d 185 Pfam PF09819 ABC-type cobalt transport system, permease component 8 126 2.4E-30 T 12-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted NPD12_993 c1f0470c896e4753440d70965821d618 1198 Gene3D G3DSA:3.90.1240.10 127 502 7.1E-146 T 12-10-2018 NPD12_993 c1f0470c896e4753440d70965821d618 1198 Gene3D G3DSA:3.90.1240.10 1 125 2.3E-53 T 12-10-2018 NPD12_993 c1f0470c896e4753440d70965821d618 1198 SUPERFAMILY SSF58091 498 830 6.15E-122 T 12-10-2018 IPR036248 Clostridium neurotoxin, translocation domain NPD12_993 c1f0470c896e4753440d70965821d618 1198 Pfam PF07953 Clostridium neurotoxin, N-terminal receptor binding 848 1024 1.2E-59 T 12-10-2018 IPR012928 Clostridium neurotoxin, receptor binding N-terminal GO:0005576|GO:0009405|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 Pfam PF01742 Clostridial neurotoxin zinc protease 1 397 7.7E-149 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 Gene3D G3DSA:2.60.120.200 834 1038 5.1E-46 T 12-10-2018 NPD12_993 c1f0470c896e4753440d70965821d618 1198 SUPERFAMILY SSF55486 1 509 3.66E-169 T 12-10-2018 NPD12_993 c1f0470c896e4753440d70965821d618 1198 Pfam PF08470 Nontoxic nonhaemagglutinin C-terminal 1032 1196 9.6E-95 T 12-10-2018 IPR013677 Nontoxic nonhaemagglutinin C-terminal NPD12_993 c1f0470c896e4753440d70965821d618 1198 PRINTS PR00760 Bontoxilysin signature 214 226 1.4E-53 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 PRINTS PR00760 Bontoxilysin signature 30 46 1.4E-53 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 PRINTS PR00760 Bontoxilysin signature 88 110 1.4E-53 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 PRINTS PR00760 Bontoxilysin signature 261 277 1.4E-53 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 PRINTS PR00760 Bontoxilysin signature 6 22 1.4E-53 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 PRINTS PR00760 Bontoxilysin signature 63 79 1.4E-53 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_993 c1f0470c896e4753440d70965821d618 1198 Gene3D G3DSA:1.20.1120.10 503 833 6.7E-174 T 12-10-2018 IPR036248 Clostridium neurotoxin, translocation domain NPD12_993 c1f0470c896e4753440d70965821d618 1198 Gene3D G3DSA:2.80.10.50 1039 1198 2.3E-83 T 12-10-2018 NPD12_993 c1f0470c896e4753440d70965821d618 1198 SUPERFAMILY SSF49899 840 1023 2.44E-38 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily NPD12_942 494d0c9448fa1a33f8d487b327b6edd0 205 Gene3D G3DSA:3.40.50.150 52 205 3.1E-39 T 12-10-2018 NPD12_942 494d0c9448fa1a33f8d487b327b6edd0 205 SUPERFAMILY SSF53335 24 201 6.38E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_942 494d0c9448fa1a33f8d487b327b6edd0 205 Pfam PF13847 Methyltransferase domain 78 202 1.9E-33 T 12-10-2018 IPR025714 Methyltransferase domain NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 Gene3D G3DSA:3.30.450.20 218 322 9.4E-11 T 12-10-2018 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 SUPERFAMILY SSF46689 547 642 1.48E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 SMART SM00382 353 498 1.1E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 Gene3D G3DSA:1.10.10.60 580 644 7.3E-15 T 12-10-2018 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 Gene3D G3DSA:1.10.8.60 505 579 1.5E-23 T 12-10-2018 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 547 556 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 Gene3D G3DSA:3.40.50.300 323 504 6.3E-65 T 12-10-2018 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 Gene3D G3DSA:3.30.450.40 15 202 3.6E-59 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 Pfam PF02954 Bacterial regulatory protein, Fis family 599 640 3.5E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 Pfam PF00158 Sigma-54 interaction domain 333 500 1.3E-68 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 606 623 4.0E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 623 643 4.0E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 SUPERFAMILY SSF55781 60 199 3.47E-6 T 12-10-2018 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 357 370 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_1867 86731b9e8dd1fe055d82c1e5d3900cba 650 SUPERFAMILY SSF52540 333 578 2.66E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 Gene3D G3DSA:3.40.50.150 65 273 1.7E-83 T 12-10-2018 NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 SUPERFAMILY SSF55174 5 71 7.95E-12 T 12-10-2018 NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 Pfam PF01479 S4 domain 6 50 2.0E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 Gene3D G3DSA:3.10.290.10 1 64 3.9E-22 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 Pfam PF01728 FtsJ-like methyltransferase 62 241 2.1E-18 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 238 1.3E-86 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 SUPERFAMILY SSF53335 55 249 8.31E-22 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 PIRSF PIRSF005578 1 265 5.0E-103 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 NPD12_2046 ae293c52fc2d8871238d685c357f6459 273 SMART SM00363 6 69 7.6E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_2341 f9e39e69b661ac5d981c87f296b093e2 638 Gene3D G3DSA:3.40.50.2030 419 634 1.7E-75 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2341 f9e39e69b661ac5d981c87f296b093e2 638 SUPERFAMILY SSF56821 4 637 3.82E-182 T 12-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 NPD12_2341 f9e39e69b661ac5d981c87f296b093e2 638 Gene3D G3DSA:1.20.1270.30 69 241 1.9E-51 T 12-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 NPD12_2341 f9e39e69b661ac5d981c87f296b093e2 638 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 14 637 2.5E-273 T 12-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 NPD12_2341 f9e39e69b661ac5d981c87f296b093e2 638 Gene3D G3DSA:3.40.50.2030 242 416 2.1E-53 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2341 f9e39e69b661ac5d981c87f296b093e2 638 Pfam PF03063 Prismane/CO dehydrogenase family 54 617 6.3E-137 T 12-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2341 f9e39e69b661ac5d981c87f296b093e2 638 PIRSF PIRSF005023 3 638 5.7E-254 T 12-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 NPD12_762 9448f6b67bb1b857de693b927c316120 570 SUPERFAMILY SSF52540 330 565 7.01E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_762 9448f6b67bb1b857de693b927c316120 570 SUPERFAMILY SSF90123 8 317 7.85E-65 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_762 9448f6b67bb1b857de693b927c316120 570 Pfam PF00664 ABC transporter transmembrane region 21 289 5.0E-48 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_762 9448f6b67bb1b857de693b927c316120 570 SMART SM00382 359 543 5.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_762 9448f6b67bb1b857de693b927c316120 570 Pfam PF00005 ABC transporter 351 497 6.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_762 9448f6b67bb1b857de693b927c316120 570 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_762 9448f6b67bb1b857de693b927c316120 570 Gene3D G3DSA:3.40.50.300 330 570 3.8E-72 T 12-10-2018 NPD12_762 9448f6b67bb1b857de693b927c316120 570 Gene3D G3DSA:1.20.1560.10 1 321 4.0E-65 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 SUPERFAMILY SSF51735 228 359 3.23E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Pfam PF02080 TrkA-C domain 383 449 2.2E-11 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Pfam PF02080 TrkA-C domain 153 221 2.8E-12 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 SUPERFAMILY SSF51735 1 149 4.97E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 SUPERFAMILY SSF116726 134 221 4.05E-14 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Gene3D G3DSA:3.40.50.720 2 136 4.9E-47 T 12-10-2018 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.2E-17 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.2E-17 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 4.2E-17 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.2E-17 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.2E-17 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Pfam PF02254 TrkA-N domain 230 346 3.6E-21 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Pfam PF02254 TrkA-N domain 3 122 2.7E-30 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Gene3D G3DSA:3.30.70.1450 370 451 3.4E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Gene3D G3DSA:3.40.50.720 229 360 6.0E-32 T 12-10-2018 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 SUPERFAMILY SSF116726 375 449 2.22E-10 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1580 26f42e3c0096f8a272fe51041f31c539 455 Gene3D G3DSA:3.30.70.1450 137 227 3.2E-20 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1304 4e696d78d2e0b39b55b033d59709e159 319 PIRSF PIRSF018688 1 303 9.1E-84 T 12-10-2018 IPR016732 Uncharacterised conserved protein UCP018688 NPD12_1304 4e696d78d2e0b39b55b033d59709e159 319 SUPERFAMILY SSF55729 2 142 6.36E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1304 4e696d78d2e0b39b55b033d59709e159 319 Gene3D G3DSA:3.40.630.30 4 299 1.3E-93 T 12-10-2018 NPD12_1304 4e696d78d2e0b39b55b033d59709e159 319 SUPERFAMILY SSF55729 143 300 1.48E-49 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1304 4e696d78d2e0b39b55b033d59709e159 319 Gene3D G3DSA:3.40.630.30 130 296 1.3E-93 T 12-10-2018 NPD12_1304 4e696d78d2e0b39b55b033d59709e159 319 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 26 300 2.1E-44 T 12-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 SMART SM00342 201 283 2.3E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 267 283 4.6E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 267 4.6E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 Gene3D G3DSA:1.10.10.60 178 234 2.0E-17 T 12-10-2018 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 Gene3D G3DSA:1.10.10.60 235 288 5.2E-15 T 12-10-2018 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 Pfam PF02311 AraC-like ligand binding domain 26 99 3.2E-7 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 SUPERFAMILY SSF51215 31 167 1.06E-12 T 12-10-2018 IPR037923 Transcription regulator HTH-like NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 SUPERFAMILY SSF46689 238 287 3.54E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 Gene3D G3DSA:2.60.120.10 8 107 8.6E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 SUPERFAMILY SSF46689 184 236 3.4E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_739 eabe5dcba77f73c0423e363bd30d1782 289 Pfam PF12833 Helix-turn-helix domain 208 284 1.8E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2022 518cdc6d47b6f5a9f4ed4c505242dc41 508 Pfam PF13520 Amino acid permease 13 481 2.4E-28 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2022 518cdc6d47b6f5a9f4ed4c505242dc41 508 PIRSF PIRSF006060 1 507 1.2E-44 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2022 518cdc6d47b6f5a9f4ed4c505242dc41 508 Gene3D G3DSA:1.20.1740.10 5 506 7.9E-13 T 12-10-2018 NPD12_2179 21ca3e5f773828f0ae9c0928d3c9322f 379 Gene3D G3DSA:3.40.640.10 15 260 3.0E-111 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2179 21ca3e5f773828f0ae9c0928d3c9322f 379 PIRSF PIRSF000524 1 378 1.1E-93 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 NPD12_2179 21ca3e5f773828f0ae9c0928d3c9322f 379 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 182 202 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site NPD12_2179 21ca3e5f773828f0ae9c0928d3c9322f 379 Gene3D G3DSA:3.90.1150.10 10 367 3.0E-111 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_2179 21ca3e5f773828f0ae9c0928d3c9322f 379 SUPERFAMILY SSF53383 2 363 1.24E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2179 21ca3e5f773828f0ae9c0928d3c9322f 379 Pfam PF00266 Aminotransferase class-V 29 323 4.0E-31 T 12-10-2018 IPR000192 Aminotransferase class V domain NPD12_1581 0933589f75978c128b11e8fdd4344bdd 481 Pfam PF02386 Cation transport protein 39 476 6.5E-52 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 NPD12_1581 0933589f75978c128b11e8fdd4344bdd 481 PIRSF PIRSF006247 1 480 1.7E-162 T 12-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 924 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Gene3D G3DSA:1.20.1580.10 91 494 6.2E-253 T 12-10-2018 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 SUPERFAMILY SSF52540 614 914 2.5E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Pfam PF00005 ABC transporter 789 860 4.4E-5 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 SUPERFAMILY SSF52540 10 571 2.43E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Gene3D G3DSA:1.20.1580.10 693 830 2.4E-146 T 12-10-2018 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 940 22.865 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Gene3D G3DSA:1.10.8.280 286 405 6.2E-253 T 12-10-2018 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Gene3D G3DSA:3.40.50.300 614 936 2.4E-146 T 12-10-2018 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Gene3D G3DSA:3.30.190.20 131 241 6.2E-253 T 12-10-2018 NPD12_3541 7fb5707312251cc5aa9e228950d88236 940 Gene3D G3DSA:3.40.50.300 6 596 6.2E-253 T 12-10-2018 NPD12_614 182fe930979380d967a00c33d667666d 267 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site NPD12_614 182fe930979380d967a00c33d667666d 267 Gene3D G3DSA:3.40.190.10 42 261 3.3E-78 T 12-10-2018 NPD12_614 182fe930979380d967a00c33d667666d 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 262 5.5E-70 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_614 182fe930979380d967a00c33d667666d 267 SUPERFAMILY SSF53850 1 263 1.6E-75 T 12-10-2018 NPD12_614 182fe930979380d967a00c33d667666d 267 Gene3D G3DSA:3.40.190.10 126 219 3.3E-78 T 12-10-2018 NPD12_614 182fe930979380d967a00c33d667666d 267 SMART SM00062 40 263 9.4E-75 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_614 182fe930979380d967a00c33d667666d 267 SMART SM00079 40 262 1.7E-5 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 NPD12_2315 9975d5b7561a4e8129ae5bfb7b336a40 261 SMART SM00893 22 213 2.1E-67 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_2315 9975d5b7561a4e8129ae5bfb7b336a40 261 PIRSF PIRSF000090 1 261 2.7E-98 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 NPD12_2315 9975d5b7561a4e8129ae5bfb7b336a40 261 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 157 177 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 NPD12_2315 9975d5b7561a4e8129ae5bfb7b336a40 261 Gene3D G3DSA:3.40.50.620 1 261 5.3E-101 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2315 9975d5b7561a4e8129ae5bfb7b336a40 261 SUPERFAMILY SSF52402 1 256 1.6E-83 T 12-10-2018 NPD12_2315 9975d5b7561a4e8129ae5bfb7b336a40 261 Pfam PF01012 Electron transfer flavoprotein domain 23 208 6.2E-54 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 Gene3D G3DSA:2.40.50.140 1 96 5.4E-22 T 12-10-2018 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 4.3E-19 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 4.3E-19 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 4.3E-19 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 4.3E-19 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 Gene3D G3DSA:3.30.930.10 98 418 1.4E-102 T 12-10-2018 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 14 429 6.3E-134 T 12-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 SUPERFAMILY SSF55681 98 427 4.98E-80 T 12-10-2018 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 Pfam PF01336 OB-fold nucleic acid binding domain 18 90 4.8E-12 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 429 39.485 T 12-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 419 1.4E-77 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_1209 2bf5d3af6ceb83474e4df5f06e7086ee 429 SUPERFAMILY SSF50249 5 98 1.01E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Gene3D G3DSA:3.30.420.40 98 242 4.5E-68 T 12-10-2018 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 906 1224 1.6E-57 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 SUPERFAMILY SSF53067 6 257 6.76E-57 T 12-10-2018 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 SUPERFAMILY SSF53067 321 576 1.73E-50 T 12-10-2018 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 8 257 3.5E-21 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 322 576 1.8E-35 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Gene3D G3DSA:3.30.420.40 322 576 1.0E-82 T 12-10-2018 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Gene3D G3DSA:3.30.420.40 7 257 4.5E-68 T 12-10-2018 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 672 891 9.8E-83 T 12-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 NPD12_3281 e7c56a4d531f4314d901d1ccf4f440de 1430 Gene3D G3DSA:3.30.420.40 416 559 1.0E-82 T 12-10-2018 NPD12_2866 0ad208895b32f1d533df63e5ba4feee0 480 Gene3D G3DSA:3.30.1360.60 400 480 9.7E-22 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_2866 0ad208895b32f1d533df63e5ba4feee0 480 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 369 464 2.6E-16 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 NPD12_2866 0ad208895b32f1d533df63e5ba4feee0 480 Pfam PF00367 phosphotransferase system, EIIB 406 439 4.1E-12 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_2866 0ad208895b32f1d533df63e5ba4feee0 480 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 417 434 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_2866 0ad208895b32f1d533df63e5ba4feee0 480 Pfam PF02378 Phosphotransferase system, EIIC 15 312 3.4E-75 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_2866 0ad208895b32f1d533df63e5ba4feee0 480 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 10 475 6.9E-172 T 12-10-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 NPD12_2866 0ad208895b32f1d533df63e5ba4feee0 480 SUPERFAMILY SSF55604 404 475 7.59E-17 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_2969 3b3c86dbb9bf5b58e74a79b30ee1c200 123 Gene3D G3DSA:1.10.10.10 10 122 7.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2969 3b3c86dbb9bf5b58e74a79b30ee1c200 123 SUPERFAMILY SSF46785 6 80 4.79E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2969 3b3c86dbb9bf5b58e74a79b30ee1c200 123 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.6E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2969 3b3c86dbb9bf5b58e74a79b30ee1c200 123 SMART SM00345 17 76 7.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2802 d616f60cc12825fe9e36b087a411144a 183 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 3 175 1.1E-59 T 12-10-2018 IPR006287 Protein/nucleic acid deglycase DJ-1 Reactome: R-HSA-3899300 NPD12_2802 d616f60cc12825fe9e36b087a411144a 183 Pfam PF01965 DJ-1/PfpI family 3 164 4.2E-50 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 NPD12_2802 d616f60cc12825fe9e36b087a411144a 183 Gene3D G3DSA:3.40.50.880 1 182 4.5E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2802 d616f60cc12825fe9e36b087a411144a 183 SUPERFAMILY SSF52317 1 173 4.59E-53 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2468 8ac9a924209c154e49f4b9c0ca4ee595 90 Pfam PF04296 Protein of unknown function (DUF448) 9 82 1.6E-30 T 12-10-2018 IPR007393 Domain of unknown function DUF448 NPD12_2468 8ac9a924209c154e49f4b9c0ca4ee595 90 Gene3D G3DSA:3.30.1230.10 1 90 1.0E-36 T 12-10-2018 IPR035931 YlxR-like superfamily NPD12_2468 8ac9a924209c154e49f4b9c0ca4ee595 90 SUPERFAMILY SSF64376 4 86 1.96E-28 T 12-10-2018 IPR035931 YlxR-like superfamily NPD12_142 30d3e512f861c995b787b39c85313781 387 Pfam PF04015 Domain of unknown function (DUF362) 44 242 2.1E-45 T 12-10-2018 IPR007160 Domain of unknown function DUF362 NPD12_142 30d3e512f861c995b787b39c85313781 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 321 332 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_142 30d3e512f861c995b787b39c85313781 387 Pfam PF12838 4Fe-4S dicluster domain 320 370 1.7E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_142 30d3e512f861c995b787b39c85313781 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 356 367 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_142 30d3e512f861c995b787b39c85313781 387 Gene3D G3DSA:3.30.70.3270 304 385 2.0E-11 T 12-10-2018 NPD12_142 30d3e512f861c995b787b39c85313781 387 SUPERFAMILY SSF54862 302 374 7.67E-15 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 627 1.4E-25 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 352 6.4E-46 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 586 702 1.4E-34 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 645 670 9.8E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 613 629 9.8E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 585 601 9.8E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 862 879 9.8E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 469 487 9.8E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 SMART SM00831 1 75 4.9E-13 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 2.2E-42 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 543 2.2E-42 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 637 649 2.2E-42 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 613 632 2.2E-42 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 2.2E-42 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 522 2.2E-42 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Gene3D G3DSA:2.70.150.10 14 231 2.4E-281 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Gene3D G3DSA:1.20.1110.10 53 873 2.4E-281 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 70 4.0E-17 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Pfam PF00689 Cation transporting ATPase, C-terminus 698 874 5.1E-43 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 SUPERFAMILY SSF81665 8 877 7.06E-120 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Pfam PF00122 E1-E2 ATPase 116 308 8.3E-55 T 12-10-2018 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Gene3D G3DSA:3.40.50.1000 325 658 2.4E-281 T 12-10-2018 IPR023214 HAD superfamily NPD12_2124 0990357ceb3503054cfd950368e2da74 879 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 5 872 5.9E-155 T 12-10-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 Gene3D G3DSA:3.40.1110.10 338 518 2.4E-281 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 SUPERFAMILY SSF81653 119 226 1.09E-30 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_2124 0990357ceb3503054cfd950368e2da74 879 SUPERFAMILY SSF56784 326 717 6.59E-62 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1220 09b29713da938a3a9b2a0891aa47522b 69 Gene3D G3DSA:2.30.30.90 1 69 5.5E-16 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain NPD12_1220 09b29713da938a3a9b2a0891aa47522b 69 Pfam PF04023 FeoA domain 1 69 1.6E-14 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1220 09b29713da938a3a9b2a0891aa47522b 69 SMART SM00899 1 69 1.7E-8 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1220 09b29713da938a3a9b2a0891aa47522b 69 SUPERFAMILY SSF50037 3 69 8.24E-12 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal NPD12_264 a93bbbbea63c3557982cb379b6fff98a 336 Gene3D G3DSA:3.90.1200.10 96 335 3.6E-74 T 12-10-2018 NPD12_264 a93bbbbea63c3557982cb379b6fff98a 336 SUPERFAMILY SSF56112 2 332 6.92E-53 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_264 a93bbbbea63c3557982cb379b6fff98a 336 Gene3D G3DSA:3.30.200.20 1 94 1.3E-22 T 12-10-2018 NPD12_264 a93bbbbea63c3557982cb379b6fff98a 336 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 16 331 1.1E-96 T 12-10-2018 IPR014255 Spore coat protein CotS NPD12_264 a93bbbbea63c3557982cb379b6fff98a 336 Pfam PF01636 Phosphotransferase enzyme family 25 249 3.0E-13 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 Pfam PF01467 Cytidylyltransferase-like 5 133 1.2E-23 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 34.767 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.2E-47 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.2E-47 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.2E-47 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.2E-47 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.2E-47 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 2.8E-63 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 Gene3D G3DSA:3.40.50.620 1 163 2.0E-60 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 SUPERFAMILY SSF52374 1 156 6.14E-46 T 12-10-2018 NPD12_2541 7bdcac58ad50c36c77550971e85c3391 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 59 8.2E-19 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 SMART SM00422 2 72 9.8E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 Gene3D G3DSA:3.20.80.10 126 263 5.5E-16 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 SMART SM00871 121 262 4.4E-9 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 Gene3D G3DSA:1.10.1660.10 1 125 6.3E-26 T 12-10-2018 NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 Pfam PF06445 GyrI-like small molecule binding domain 121 261 3.8E-10 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 SUPERFAMILY SSF46955 2 104 1.79E-25 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 SUPERFAMILY SSF55136 122 248 1.12E-11 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_3564 1632d98b48349a53b2c9aaeffbba19ce 264 Pfam PF13411 MerR HTH family regulatory protein 2 70 4.4E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.2E-33 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.2E-33 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 1.2E-33 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.2E-33 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.2E-33 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 321 1.5E-64 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 SUPERFAMILY SSF55424 337 457 7.39E-41 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 SUPERFAMILY SSF51905 3 315 5.75E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 Gene3D G3DSA:3.50.50.60 3 328 1.7E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 Gene3D G3DSA:3.50.50.60 149 271 1.7E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 2.4E-37 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PIRSF PIRSF000350 1 457 1.1E-95 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 Gene3D G3DSA:3.30.390.30 338 462 1.4E-45 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.5E-70 T 12-10-2018 NPD12_875 523cb183da03c8d9ad5d2103331fd3af 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 457 1.3E-160 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 NPD12_2323 9003ec335942113f8cdadba82dbbede6 383 Gene3D G3DSA:1.10.287.950 214 383 6.6E-38 T 12-10-2018 NPD12_2323 9003ec335942113f8cdadba82dbbede6 383 SUPERFAMILY SSF58104 219 381 3.27E-41 T 12-10-2018 NPD12_2323 9003ec335942113f8cdadba82dbbede6 383 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 258 379 1.4E-24 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2323 9003ec335942113f8cdadba82dbbede6 383 SMART SM00283 176 383 8.5E-5 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1639 0b8ea92b33c444788aec61728cd74676 346 SUPERFAMILY SSF56281 4 342 1.83E-58 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1639 0b8ea92b33c444788aec61728cd74676 346 Hamap MF_01818 Ribonuclease BN [rbn]. 2 342 31.806 T 12-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 NPD12_1639 0b8ea92b33c444788aec61728cd74676 346 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 4 339 6.0E-91 T 12-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 NPD12_1639 0b8ea92b33c444788aec61728cd74676 346 Pfam PF12706 Beta-lactamase superfamily domain 240 310 2.3E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1639 0b8ea92b33c444788aec61728cd74676 346 Pfam PF00753 Metallo-beta-lactamase superfamily 21 87 8.2E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 3 186 1.7E-62 T 12-10-2018 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 PRINTS PR00991 6-phosphofructo-2-kinase family signature 3 25 4.1E-5 T 12-10-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|Reactome: R-HSA-70171 NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 PRINTS PR00991 6-phosphofructo-2-kinase family signature 90 106 4.1E-5 T 12-10-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|Reactome: R-HSA-70171 NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 Gene3D G3DSA:3.40.50.1240 1 202 7.3E-58 T 12-10-2018 IPR029033 Histidine phosphatase superfamily NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 SUPERFAMILY SSF53254 1 195 3.14E-54 T 12-10-2018 IPR029033 Histidine phosphatase superfamily NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 PIRSF PIRSF000709 1 177 7.5E-21 T 12-10-2018 NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 SMART SM00855 2 161 2.2E-21 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 NPD12_1005 f12bb8351f561188afc46a7ab83a88a5 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 193 5.2E-52 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 PRINTS PR00990 Ribokinase signature 5 26 2.2E-30 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 PRINTS PR00990 Ribokinase signature 32 51 2.2E-30 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 PRINTS PR00990 Ribokinase signature 217 228 2.2E-30 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 PRINTS PR00990 Ribokinase signature 104 117 2.2E-30 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 PRINTS PR00990 Ribokinase signature 173 188 2.2E-30 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 Hamap MF_01987 Ribokinase [rbsK]. 1 301 26.261 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 Pfam PF00294 pfkB family carbohydrate kinase 2 294 1.1E-67 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 SUPERFAMILY SSF53613 1 302 7.79E-82 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 3 299 1.3E-116 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 NPD12_1804 faf98cc0842f31fe56ba06a746b24a48 303 Gene3D G3DSA:3.40.1190.20 1 303 2.0E-100 T 12-10-2018 IPR029056 Ribokinase-like NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 Gene3D G3DSA:1.10.10.60 55 111 8.1E-13 T 12-10-2018 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 SMART SM00342 21 103 1.7E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 Pfam PF14526 Integron-associated effector binding protein 127 291 2.9E-23 T 12-10-2018 IPR029441 Integron-associated effector binding protein NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 SUPERFAMILY SSF46689 7 55 8.96E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 99 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 Pfam PF12833 Helix-turn-helix domain 29 104 4.1E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 SUPERFAMILY SSF55136 127 293 6.8E-17 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 SMART SM00871 123 292 7.3E-29 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 Gene3D G3DSA:1.10.10.60 2 54 3.8E-17 T 12-10-2018 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 Gene3D G3DSA:3.20.80.10 123 296 1.7E-36 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 SUPERFAMILY SSF46689 58 107 5.82E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 72 87 1.7E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_2297 e317539938a6682512ea5cfacef6b9d9 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 87 103 1.7E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_2182 3690bcc4271297e1d9f284072e58819b 73 Gene3D G3DSA:2.30.31.70 1 72 2.9E-33 T 12-10-2018 NPD12_2182 3690bcc4271297e1d9f284072e58819b 73 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 20 67 3.5E-11 T 12-10-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0006355 NPD12_2182 3690bcc4271297e1d9f284072e58819b 73 PIRSF PIRSF037246 1 73 6.4E-37 T 12-10-2018 IPR017154 Uncharacterised conserved protein UCP037246 NPD12_1344 d5aac5d3d25be1faad89ca2fa254858c 264 Pfam PF13240 zinc-ribbon domain 2 23 4.1E-9 T 12-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 NPD12_2109 adb56bb0144b902c847a638cc025426e 162 Pfam PF00994 Probable molybdopterin binding domain 5 148 2.2E-37 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2109 adb56bb0144b902c847a638cc025426e 162 Gene3D G3DSA:3.40.980.10 1 162 3.2E-58 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_2109 adb56bb0144b902c847a638cc025426e 162 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 142 9.1E-40 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2109 adb56bb0144b902c847a638cc025426e 162 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 NPD12_2109 adb56bb0144b902c847a638cc025426e 162 SMART SM00852 5 149 4.3E-31 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_2109 adb56bb0144b902c847a638cc025426e 162 PIRSF PIRSF006443 1 156 9.4E-42 T 12-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 NPD12_2109 adb56bb0144b902c847a638cc025426e 162 SUPERFAMILY SSF53218 1 152 6.94E-47 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_534 925022f2c71e0a49c614427e99686b72 223 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 10 183 2.3E-41 T 12-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 NPD12_534 925022f2c71e0a49c614427e99686b72 223 Pfam PF04205 FMN-binding domain 91 178 1.1E-22 T 12-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 NPD12_534 925022f2c71e0a49c614427e99686b72 223 SMART SM00900 91 181 2.0E-31 T 12-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 NPD12_534 925022f2c71e0a49c614427e99686b72 223 PIRSF PIRSF006091 1 194 5.2E-50 T 12-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 NPD12_534 925022f2c71e0a49c614427e99686b72 223 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 3 183 25.551 T 12-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 NPD12_909 3cc2735a199975578d818d007e619c2c 517 SUPERFAMILY SSF52540 306 511 2.42E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_909 3cc2735a199975578d818d007e619c2c 517 Pfam PF00005 ABC transporter 20 190 4.9E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_909 3cc2735a199975578d818d007e619c2c 517 Gene3D G3DSA:3.40.50.300 297 516 2.4E-40 T 12-10-2018 NPD12_909 3cc2735a199975578d818d007e619c2c 517 Pfam PF00005 ABC transporter 340 468 7.3E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_909 3cc2735a199975578d818d007e619c2c 517 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_909 3cc2735a199975578d818d007e619c2c 517 Pfam PF12848 ABC transporter 229 314 1.1E-23 T 12-10-2018 IPR032781 ABC-transporter extension domain NPD12_909 3cc2735a199975578d818d007e619c2c 517 SMART SM00382 348 513 1.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_909 3cc2735a199975578d818d007e619c2c 517 SMART SM00382 28 237 2.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_909 3cc2735a199975578d818d007e619c2c 517 SUPERFAMILY SSF52540 3 248 2.62E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_909 3cc2735a199975578d818d007e619c2c 517 Gene3D G3DSA:3.40.50.300 2 287 2.9E-60 T 12-10-2018 NPD12_909 3cc2735a199975578d818d007e619c2c 517 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_709 b9a6045b672e3b8812732f2793509ceb 178 Pfam PF02417 Chromate transporter 5 169 8.1E-49 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 NPD12_2221 468abb241ab7489853d0e71ed101b26b 160 SUPERFAMILY SSF55729 1 147 3.32E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2221 468abb241ab7489853d0e71ed101b26b 160 Gene3D G3DSA:3.40.630.30 1 160 1.8E-41 T 12-10-2018 NPD12_2221 468abb241ab7489853d0e71ed101b26b 160 Pfam PF00583 Acetyltransferase (GNAT) family 16 138 1.1E-11 T 12-10-2018 IPR000182 GNAT domain NPD12_3239 5e86008a894214e88c0b2ad35137d18c 339 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 339 2.2E-104 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 NPD12_3239 5e86008a894214e88c0b2ad35137d18c 339 SUPERFAMILY SSF55681 93 339 5.97E-80 T 12-10-2018 NPD12_3239 5e86008a894214e88c0b2ad35137d18c 339 SUPERFAMILY SSF46589 16 99 2.25E-19 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 NPD12_3239 5e86008a894214e88c0b2ad35137d18c 339 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 86 1.9E-23 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 NPD12_3239 5e86008a894214e88c0b2ad35137d18c 339 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 339 46.696 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 NPD12_3239 5e86008a894214e88c0b2ad35137d18c 339 Pfam PF01409 tRNA synthetases class II core domain (F) 93 339 5.8E-105 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 NPD12_3239 5e86008a894214e88c0b2ad35137d18c 339 Gene3D G3DSA:3.30.930.10 8 339 5.9E-123 T 12-10-2018 NPD12_2254 70f31edcc490f6744c068dd33d0ecf40 102 Pfam PF00936 BMC domain 6 83 1.5E-26 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_2254 70f31edcc490f6744c068dd33d0ecf40 102 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 5 63 3.0E-22 T 12-10-2018 NPD12_2254 70f31edcc490f6744c068dd33d0ecf40 102 SUPERFAMILY SSF143414 4 95 1.14E-31 T 12-10-2018 IPR037233 CcmK-like superfamily NPD12_2254 70f31edcc490f6744c068dd33d0ecf40 102 Gene3D G3DSA:3.30.70.1710 1 99 1.7E-38 T 12-10-2018 NPD12_2254 70f31edcc490f6744c068dd33d0ecf40 102 SMART SM00877 5 83 2.0E-34 T 12-10-2018 IPR000249 Microcompartment protein, bacteria NPD12_962 a35fc104813563bd8fb46121c1a9d3c5 306 SMART SM00382 30 212 5.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_962 a35fc104813563bd8fb46121c1a9d3c5 306 Pfam PF00005 ABC transporter 22 162 8.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_962 a35fc104813563bd8fb46121c1a9d3c5 306 Gene3D G3DSA:3.40.50.300 2 240 3.8E-56 T 12-10-2018 NPD12_962 a35fc104813563bd8fb46121c1a9d3c5 306 SUPERFAMILY SSF52540 4 224 5.02E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_962 a35fc104813563bd8fb46121c1a9d3c5 306 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_43 034de2e085b7a567244a111161fffbd7 190 SUPERFAMILY SSF48498 78 189 2.0E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily NPD12_43 034de2e085b7a567244a111161fffbd7 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 183 3.7E-29 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal NPD12_43 034de2e085b7a567244a111161fffbd7 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.9E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_43 034de2e085b7a567244a111161fffbd7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_43 034de2e085b7a567244a111161fffbd7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_43 034de2e085b7a567244a111161fffbd7 190 Gene3D G3DSA:1.10.357.10 56 190 7.1E-34 T 12-10-2018 NPD12_43 034de2e085b7a567244a111161fffbd7 190 SUPERFAMILY SSF46689 7 65 2.24E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_43 034de2e085b7a567244a111161fffbd7 190 Gene3D G3DSA:1.10.10.60 1 55 5.9E-27 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SUPERFAMILY SSF69304 1259 1337 7.06E-5 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 677 698 71.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 919 943 11.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 354 375 220.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 181 202 2.2 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 225 246 190.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 611 632 5.9 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 633 654 56.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 699 727 250.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 655 676 190.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 247 267 120.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 270 289 110.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 897 918 200.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00365 203 224 110.0 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SUPERFAMILY SSF52058 158 318 2.31E-27 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SUPERFAMILY SSF52058 581 753 2.15E-32 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SUPERFAMILY SSF52058 812 974 1.45E-22 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Pfam PF07532 Bacterial Ig-like domain (group 4) 1011 1068 6.4E-18 T 12-10-2018 IPR011081 Bacterial Ig-related NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Pfam PF16472 Domain of unknown function (DUF5050) 1088 1349 7.5E-50 T 12-10-2018 IPR032485 Domain of unknown function DUF5050 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 897 918 270.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 461 481 81.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 655 676 92.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 699 722 260.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 203 224 99.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 611 636 31.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 376 397 290.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 677 698 34.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SMART SM00369 919 944 86.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Gene3D G3DSA:3.80.10.10 117 318 1.1E-42 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Gene3D G3DSA:3.80.10.10 761 999 2.9E-30 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Gene3D G3DSA:3.80.10.10 322 462 5.5E-24 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Gene3D G3DSA:2.120.10.30 1145 1350 7.1E-9 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Pfam PF12799 Leucine Rich repeats (2 copies) 635 674 5.3E-7 T 12-10-2018 IPR025875 Leucine rich repeat 4 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Pfam PF12799 Leucine Rich repeats (2 copies) 270 301 1.3E-7 T 12-10-2018 IPR025875 Leucine rich repeat 4 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SUPERFAMILY SSF69304 1091 1280 1.57E-12 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 SUPERFAMILY SSF52058 353 549 9.18E-27 T 12-10-2018 NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Gene3D G3DSA:3.80.10.10 561 760 4.9E-42 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_1934 f6beb26638879c709c07733a56edc310 1355 Gene3D G3DSA:3.80.10.10 463 560 2.8E-12 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 SUPERFAMILY SSF109604 239 403 1.06E-30 T 12-10-2018 NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 SMART SM00471 243 378 2.1E-10 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 SMART SM00471 39 165 0.75 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 SUPERFAMILY SSF109604 34 193 2.51E-22 T 12-10-2018 NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 Gene3D G3DSA:1.10.3210.10 196 394 4.1E-48 T 12-10-2018 NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 Gene3D G3DSA:1.10.3210.10 33 195 8.6E-30 T 12-10-2018 NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 Pfam PF01966 HD domain 44 153 2.1E-8 T 12-10-2018 IPR006674 HD domain NPD12_3448 aba8a884f5c161a3edf82a127f0085e4 413 Pfam PF01966 HD domain 248 368 4.0E-18 T 12-10-2018 IPR006674 HD domain NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 PIRSF PIRSF000114 1 331 9.5E-111 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 179 316 5.5E-54 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 Gene3D G3DSA:3.40.50.720 1 186 1.2E-65 T 12-10-2018 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 321 36.939 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 SUPERFAMILY SSF48179 178 330 4.76E-56 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 158 1.8E-55 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 SUPERFAMILY SSF51735 5 177 1.64E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 Gene3D G3DSA:1.10.1040.10 188 332 3.9E-53 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 187 208 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 132 152 2.5E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 237 254 2.5E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 172 196 2.5E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 2.5E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 2.5E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_2566 2a3f45de6ea787af6988cbf2a39c05d8 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 197 221 2.5E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 NPD12_111 5e88a50d0ed715830a742dbd27aaae6d 81 Pfam PF11823 Protein of unknown function (DUF3343) 3 71 3.7E-23 T 12-10-2018 IPR021778 Domain of unknown function DUF3343 NPD12_2305 a72c911a488aa2cca45604771119c303 150 Pfam PF12638 Staygreen protein 3 146 7.3E-59 T 12-10-2018 IPR024438 Staygreen protein NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 Gene3D G3DSA:3.40.50.620 8 209 1.4E-81 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 SUPERFAMILY SSF52467 211 333 1.87E-47 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 PIRSF PIRSF000089 9 337 1.0E-121 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 213 296 1.2E-35 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 SUPERFAMILY SSF52402 11 207 1.4E-61 T 12-10-2018 NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 Gene3D G3DSA:3.40.50.1220 210 342 5.0E-55 T 12-10-2018 NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 SMART SM00893 13 202 1.2E-59 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_2314 b076922c3a8e342eebc96db6d7344664 349 Pfam PF01012 Electron transfer flavoprotein domain 13 192 1.5E-50 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3577 e9719fc6e347fad791486ce685046859 323 Gene3D G3DSA:3.40.50.1360 50 313 4.2E-87 T 12-10-2018 NPD12_3577 e9719fc6e347fad791486ce685046859 323 Pfam PF13412 Winged helix-turn-helix DNA-binding 19 50 3.2E-6 T 12-10-2018 NPD12_3577 e9719fc6e347fad791486ce685046859 323 SUPERFAMILY SSF100950 56 315 2.34E-71 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_3577 e9719fc6e347fad791486ce685046859 323 Pfam PF04198 Putative sugar-binding domain 57 313 2.2E-76 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 NPD12_3577 e9719fc6e347fad791486ce685046859 323 SUPERFAMILY SSF46785 15 52 2.58E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3577 e9719fc6e347fad791486ce685046859 323 Gene3D G3DSA:1.10.10.60 1 49 6.5E-23 T 12-10-2018 NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 SMART SM00862 144 218 8.3E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 Gene3D G3DSA:1.10.10.10 126 219 1.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 SMART SM00448 2 111 2.7E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 Gene3D G3DSA:3.40.50.2300 1 125 3.9E-30 T 12-10-2018 NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 SUPERFAMILY SSF52172 2 127 2.99E-34 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 1.5E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 SUPERFAMILY SSF46894 118 218 7.37E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_1825 b3b6456a3453ab282aedc8fc23ec3717 219 Pfam PF00072 Response regulator receiver domain 4 112 2.3E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 Gene3D G3DSA:3.40.50.1380 1 197 4.2E-85 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 SUPERFAMILY SSF53927 203 499 1.3E-122 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 SMART SM00798 133 437 4.9E-181 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 Gene3D G3DSA:3.40.140.20 368 499 3.5E-53 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 PIRSF PIRSF000414 1 499 2.5E-210 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 499 43.2 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 Gene3D G3DSA:3.40.140.20 199 355 2.4E-61 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 SMART SM00851 14 128 2.1E-51 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 Pfam PF02142 MGS-like domain 14 128 1.1E-24 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 SUPERFAMILY SSF52335 2 191 3.82E-65 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 436 8.5E-117 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2927 dca2d2c638db328e6bc1bd6342f1390c 499 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 499 4.2E-197 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2458 6f58e9e993a1019086b559dcfbf7076c 90 SUPERFAMILY SSF50346 6 80 1.88E-8 T 12-10-2018 IPR011033 PRC-barrel-like superfamily NPD12_2458 6f58e9e993a1019086b559dcfbf7076c 90 Pfam PF05239 PRC-barrel domain 4 84 4.2E-10 T 12-10-2018 IPR027275 PRC-barrel domain NPD12_2458 6f58e9e993a1019086b559dcfbf7076c 90 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 7 80 2.2E-28 T 12-10-2018 IPR014238 Sporulation protein YlmC/YmxH NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 Gene3D G3DSA:1.20.1560.10 2 325 2.5E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 SUPERFAMILY SSF90123 11 322 1.83E-56 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 Pfam PF00005 ABC transporter 357 505 2.1E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 SUPERFAMILY SSF52540 337 559 5.33E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 Pfam PF00664 ABC transporter transmembrane region 25 294 7.0E-30 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 SMART SM00382 366 551 3.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2913 1db7980bfc0654a34893ac8a7df2e6af 565 Gene3D G3DSA:3.40.50.300 332 564 1.7E-75 T 12-10-2018 NPD12_1015 2925a96a196a8a59fc50e9e7a1ca5605 83 Pfam PF13684 Dihydroxyacetone kinase family 3 79 3.7E-20 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain NPD12_2675 17e213714c704c28e1b8f9f17d12f296 333 Pfam PF01992 ATP synthase (C/AC39) subunit 10 327 1.8E-61 T 12-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2675 17e213714c704c28e1b8f9f17d12f296 333 Gene3D G3DSA:1.10.132.50 6 318 7.9E-55 T 12-10-2018 NPD12_2675 17e213714c704c28e1b8f9f17d12f296 333 SUPERFAMILY SSF103486 6 329 2.75E-67 T 12-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2675 17e213714c704c28e1b8f9f17d12f296 333 Gene3D G3DSA:1.20.1690.10 81 182 7.9E-55 T 12-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2675 17e213714c704c28e1b8f9f17d12f296 333 Gene3D G3DSA:1.20.1690.10 183 289 7.9E-55 T 12-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_3752 208a994d3afc98751898df97366d29d0 234 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 202 222 1.2E-12 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 NPD12_3752 208a994d3afc98751898df97366d29d0 234 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 26 40 1.2E-12 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 NPD12_3752 208a994d3afc98751898df97366d29d0 234 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 179 197 1.2E-12 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 NPD12_3752 208a994d3afc98751898df97366d29d0 234 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 160 177 1.2E-12 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 NPD12_3752 208a994d3afc98751898df97366d29d0 234 SUPERFAMILY SSF53335 6 222 6.3E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3752 208a994d3afc98751898df97366d29d0 234 Gene3D G3DSA:3.40.50.150 4 233 2.0E-30 T 12-10-2018 NPD12_3752 208a994d3afc98751898df97366d29d0 234 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 30 36 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_3752 208a994d3afc98751898df97366d29d0 234 Pfam PF01555 DNA methylase 147 217 3.4E-12 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 NPD12_3319 5280d919456fdb0a92d3bf521219a4db 254 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 251 17.122 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 NPD12_3319 5280d919456fdb0a92d3bf521219a4db 254 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 245 4.1E-75 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 NPD12_3319 5280d919456fdb0a92d3bf521219a4db 254 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 129 141 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 NPD12_3319 5280d919456fdb0a92d3bf521219a4db 254 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 251 7.2E-72 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 NPD12_2522 1811a84a008c58958c57b06428395bfe 335 SUPERFAMILY SSF54506 1 332 8.3E-112 T 12-10-2018 NPD12_2522 1811a84a008c58958c57b06428395bfe 335 Gene3D G3DSA:3.10.310.10 6 334 2.7E-136 T 12-10-2018 NPD12_2522 1811a84a008c58958c57b06428395bfe 335 Pfam PF05544 Proline racemase 10 333 5.0E-129 T 12-10-2018 IPR008794 Proline racemase family NPD12_2522 1811a84a008c58958c57b06428395bfe 335 Gene3D G3DSA:3.10.310.10 146 311 2.7E-136 T 12-10-2018 NPD12_2522 1811a84a008c58958c57b06428395bfe 335 PIRSF PIRSF029792 1 335 8.1E-143 T 12-10-2018 IPR008794 Proline racemase family NPD12_3334 f2f63817692b0e0a03edcb8fd371b777 318 Gene3D G3DSA:1.10.10.10 1 63 4.6E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3334 f2f63817692b0e0a03edcb8fd371b777 318 Pfam PF13280 WYL domain 145 310 9.5E-38 T 12-10-2018 IPR026881 WYL domain NPD12_3334 f2f63817692b0e0a03edcb8fd371b777 318 Pfam PF08279 HTH domain 8 58 1.4E-10 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_3334 f2f63817692b0e0a03edcb8fd371b777 318 SUPERFAMILY SSF46785 6 58 5.28E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1989 72e25b1f43223d2400d8131e8d9b9ea6 471 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 NPD12_1989 72e25b1f43223d2400d8131e8d9b9ea6 471 SUPERFAMILY SSF56762 4 456 1.19E-122 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_1989 72e25b1f43223d2400d8131e8d9b9ea6 471 Pfam PF00374 Nickel-dependent hydrogenase 39 122 8.1E-22 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 NPD12_1989 72e25b1f43223d2400d8131e8d9b9ea6 471 Pfam PF00374 Nickel-dependent hydrogenase 330 456 2.8E-36 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 NPD12_1989 72e25b1f43223d2400d8131e8d9b9ea6 471 Pfam PF00374 Nickel-dependent hydrogenase 131 322 1.4E-41 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 NPD12_1989 72e25b1f43223d2400d8131e8d9b9ea6 471 Gene3D G3DSA:1.10.645.10 1 470 2.2E-146 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_1989 72e25b1f43223d2400d8131e8d9b9ea6 471 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 447 456 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 NPD12_1816 6260f6ed6dc7be10a56b3523ba258035 73 Pfam PF01206 Sulfurtransferase TusA 5 73 5.2E-16 T 12-10-2018 IPR001455 TusA-like domain NPD12_1816 6260f6ed6dc7be10a56b3523ba258035 73 Gene3D G3DSA:3.30.110.40 1 73 8.7E-15 T 12-10-2018 IPR036868 TusA-like domain superfamily NPD12_1816 6260f6ed6dc7be10a56b3523ba258035 73 SUPERFAMILY SSF64307 4 73 6.8E-17 T 12-10-2018 IPR036868 TusA-like domain superfamily NPD12_3089 bc11aafbb76fd91268e79e2be334ab4b 189 SMART SM00471 15 143 4.6E-7 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_3089 bc11aafbb76fd91268e79e2be334ab4b 189 SUPERFAMILY SSF109604 4 181 2.14E-30 T 12-10-2018 NPD12_3089 bc11aafbb76fd91268e79e2be334ab4b 189 Pfam PF01966 HD domain 19 132 1.1E-9 T 12-10-2018 IPR006674 HD domain NPD12_3089 bc11aafbb76fd91268e79e2be334ab4b 189 TIGRFAM TIGR00277 HDIG: HDIG domain 17 96 3.4E-7 T 12-10-2018 IPR006675 HDIG domain NPD12_3089 bc11aafbb76fd91268e79e2be334ab4b 189 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 11 182 5.2E-48 T 12-10-2018 IPR005249 Conserved hypothetical protein CHP00488 NPD12_3089 bc11aafbb76fd91268e79e2be334ab4b 189 Gene3D G3DSA:1.10.3210.10 1 188 2.3E-57 T 12-10-2018 NPD12_3296 3f37baeabcf925554f7252063b47b29b 189 Gene3D G3DSA:2.60.120.10 71 179 7.3E-23 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_3296 3f37baeabcf925554f7252063b47b29b 189 SMART SM00530 8 63 1.5E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3296 3f37baeabcf925554f7252063b47b29b 189 SUPERFAMILY SSF47413 3 67 5.35E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3296 3f37baeabcf925554f7252063b47b29b 189 Gene3D G3DSA:1.10.260.40 1 70 8.7E-18 T 12-10-2018 NPD12_3296 3f37baeabcf925554f7252063b47b29b 189 SUPERFAMILY SSF51182 56 184 7.68E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_3296 3f37baeabcf925554f7252063b47b29b 189 Pfam PF01381 Helix-turn-helix 9 63 3.9E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3296 3f37baeabcf925554f7252063b47b29b 189 Pfam PF07883 Cupin domain 122 178 3.4E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel NPD12_252 f668fa2d2cd530a7e55e24ca45c7917d 112 Gene3D G3DSA:1.10.10.10 1 111 1.2E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_252 f668fa2d2cd530a7e55e24ca45c7917d 112 SUPERFAMILY SSF46785 12 107 1.45E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_252 f668fa2d2cd530a7e55e24ca45c7917d 112 Pfam PF03551 Transcriptional regulator PadR-like family 16 86 2.6E-21 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal NPD12_1065 6ec6b442ff61263bc3243c212bc25dd5 286 Pfam PF01381 Helix-turn-helix 57 108 2.7E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1065 6ec6b442ff61263bc3243c212bc25dd5 286 SUPERFAMILY SSF47413 60 109 7.17E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1065 6ec6b442ff61263bc3243c212bc25dd5 286 SMART SM00530 54 108 8.7E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1065 6ec6b442ff61263bc3243c212bc25dd5 286 Gene3D G3DSA:1.10.260.40 43 111 1.0E-13 T 12-10-2018 NPD12_1231 9fa2c95e0bb826552e55dea6db0f7c39 602 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 NPD12_1231 9fa2c95e0bb826552e55dea6db0f7c39 602 SUPERFAMILY SSF55008 5 70 6.28E-16 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_1231 9fa2c95e0bb826552e55dea6db0f7c39 602 Gene3D G3DSA:2.60.40.420 334 433 2.9E-28 T 12-10-2018 IPR008972 Cupredoxin NPD12_1231 9fa2c95e0bb826552e55dea6db0f7c39 602 Gene3D G3DSA:3.30.70.100 2 70 5.5E-16 T 12-10-2018 NPD12_1231 9fa2c95e0bb826552e55dea6db0f7c39 602 Pfam PF00403 Heavy-metal-associated domain 8 67 2.8E-11 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_1231 9fa2c95e0bb826552e55dea6db0f7c39 602 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 111 303 9.5E-52 T 12-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain NPD12_1253 a53d86a2eb5ed62f0d551da84adfa9da 194 SUPERFAMILY SSF56112 20 139 4.71E-13 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_1253 a53d86a2eb5ed62f0d551da84adfa9da 194 Gene3D G3DSA:1.10.510.10 4 139 1.3E-6 T 12-10-2018 NPD12_3509 8f519500bfc450372a988b0f08213c1a 398 Gene3D G3DSA:3.40.50.150 105 329 1.2E-63 T 12-10-2018 NPD12_3509 8f519500bfc450372a988b0f08213c1a 398 Pfam PF01861 Protein of unknown function DUF43 114 307 8.0E-39 T 12-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal NPD12_3509 8f519500bfc450372a988b0f08213c1a 398 SUPERFAMILY SSF53335 186 273 1.5E-6 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_1188 7d2bd9a8cd136411dba16fb9c65079a7 127 Pfam PF00072 Response regulator receiver domain 8 121 4.6E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1188 7d2bd9a8cd136411dba16fb9c65079a7 127 Gene3D G3DSA:3.40.50.2300 4 127 7.3E-26 T 12-10-2018 NPD12_1188 7d2bd9a8cd136411dba16fb9c65079a7 127 SMART SM00448 6 121 1.2E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1188 7d2bd9a8cd136411dba16fb9c65079a7 127 SUPERFAMILY SSF52172 5 125 1.71E-24 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 Pfam PF04542 Sigma-70 region 2 54 123 2.3E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 SUPERFAMILY SSF88946 21 124 1.26E-33 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 SUPERFAMILY SSF88659 137 229 3.71E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 4 228 9.1E-121 T 12-10-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 Gene3D G3DSA:1.10.10.10 162 233 2.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 PIRSF PIRSF000770 4 233 9.8E-68 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 52 228 2.1E-28 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 198 224 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 PRINTS PR00046 Major sigma-70 factor signature 78 91 2.7E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 PRINTS PR00046 Major sigma-70 factor signature 177 189 2.7E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 PRINTS PR00046 Major sigma-70 factor signature 198 213 2.7E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 PRINTS PR00046 Major sigma-70 factor signature 213 224 2.7E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 Gene3D G3DSA:1.20.120.1810 22 123 4.0E-24 T 12-10-2018 NPD12_2588 a157d4719b4cf5d2d76f192b9187a134 234 Pfam PF04545 Sigma-70, region 4 177 225 3.9E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 NPD12_2309 28fb9aa4dd878777da4b2d47858567a9 440 PIRSF PIRSF006060 1 440 2.3E-62 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2309 28fb9aa4dd878777da4b2d47858567a9 440 Gene3D G3DSA:1.20.1740.10 1 440 4.6E-67 T 12-10-2018 NPD12_2309 28fb9aa4dd878777da4b2d47858567a9 440 Pfam PF13520 Amino acid permease 7 411 7.2E-49 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_964 918f705fac37a021517d05395ca420cc 285 Gene3D G3DSA:3.20.80.10 128 285 3.2E-37 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_964 918f705fac37a021517d05395ca420cc 285 SMART SM00342 21 104 3.4E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_964 918f705fac37a021517d05395ca420cc 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 1.0E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_964 918f705fac37a021517d05395ca420cc 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 1.0E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_964 918f705fac37a021517d05395ca420cc 285 Pfam PF14526 Integron-associated effector binding protein 131 282 1.3E-22 T 12-10-2018 IPR029441 Integron-associated effector binding protein NPD12_964 918f705fac37a021517d05395ca420cc 285 SUPERFAMILY SSF55136 128 285 4.71E-24 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_964 918f705fac37a021517d05395ca420cc 285 Pfam PF12833 Helix-turn-helix domain 27 105 1.8E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_964 918f705fac37a021517d05395ca420cc 285 SMART SM00871 128 283 9.2E-27 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_964 918f705fac37a021517d05395ca420cc 285 SUPERFAMILY SSF46689 57 108 4.48E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_964 918f705fac37a021517d05395ca420cc 285 Gene3D G3DSA:1.10.10.60 4 57 1.5E-13 T 12-10-2018 NPD12_964 918f705fac37a021517d05395ca420cc 285 SUPERFAMILY SSF46689 7 56 4.93E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_964 918f705fac37a021517d05395ca420cc 285 Gene3D G3DSA:1.10.10.60 58 113 1.8E-14 T 12-10-2018 NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 297 2.3E-53 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 Gene3D G3DSA:3.40.50.720 102 297 1.1E-124 T 12-10-2018 NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 SUPERFAMILY SSF52283 2 133 1.53E-35 T 12-10-2018 NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 SUPERFAMILY SSF51735 102 299 8.35E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 175 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 326 2.3E-28 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 Gene3D G3DSA:3.40.50.720 2 318 1.1E-124 T 12-10-2018 NPD12_3412 c5aa03bf050f3f5a57896b81461ccdae 331 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 94 109 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 TIGRFAM TIGR00835 agcS: amino acid carrier protein 15 441 7.7E-148 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 Pfam PF01235 Sodium:alanine symporter family 56 447 8.0E-147 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 PRINTS PR00175 Sodium/alanine symporter signature 94 116 1.6E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 PRINTS PR00175 Sodium/alanine symporter signature 212 231 1.6E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 PRINTS PR00175 Sodium/alanine symporter signature 351 373 1.6E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 PRINTS PR00175 Sodium/alanine symporter signature 410 430 1.6E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 PRINTS PR00175 Sodium/alanine symporter signature 184 202 1.6E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1543 dd95558959134bc1828bc1be7fd6feb7 450 PRINTS PR00175 Sodium/alanine symporter signature 307 325 1.6E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 SMART SM01390 3 87 1.0E-28 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 4 197 1.6E-65 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 SUPERFAMILY SSF55174 5 197 5.23E-59 T 12-10-2018 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 Gene3D G3DSA:3.10.290.10 87 182 1.9E-67 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 4 87 6.7E-21 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 Gene3D G3DSA:1.10.1050.10 6 197 1.9E-67 T 12-10-2018 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 ProSitePatterns PS00632 Ribosomal protein S4 signature. 86 110 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 SMART SM00363 88 153 2.1E-18 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 197 30.72 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 NPD12_3561 ce79e66b75cc1e99e841574ccc563052 197 Pfam PF01479 S4 domain 89 135 4.4E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 227 499 21.834 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 212 25.019 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 SUPERFAMILY SSF64153 10 221 6.67E-56 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 Pfam PF03853 YjeF-related protein N-terminus 26 191 3.0E-43 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 PIRSF PIRSF017184 1 500 9.7E-142 T 12-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 234 495 2.2E-64 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 Pfam PF01256 Carbohydrate kinase 251 491 2.2E-62 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 SUPERFAMILY SSF53613 231 497 1.93E-73 T 12-10-2018 IPR029056 Ribokinase-like NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 Gene3D G3DSA:3.40.50.10260 2 218 1.3E-63 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 Gene3D G3DSA:3.40.1190.20 225 500 1.5E-87 T 12-10-2018 IPR029056 Ribokinase-like NPD12_3555 43d7a2d69057d129761de7fab7d3d4da 500 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 5 213 3.5E-48 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 NPD12_1844 6a889827b18c6af5e9f46aae92ca135f 315 Pfam PF00480 ROK family 7 311 5.2E-78 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 NPD12_1844 6a889827b18c6af5e9f46aae92ca135f 315 SUPERFAMILY SSF53067 5 312 6.92E-69 T 12-10-2018 NPD12_1844 6a889827b18c6af5e9f46aae92ca135f 315 Gene3D G3DSA:3.30.420.40 7 308 8.8E-100 T 12-10-2018 NPD12_1844 6a889827b18c6af5e9f46aae92ca135f 315 Gene3D G3DSA:3.30.420.40 128 295 8.8E-100 T 12-10-2018 NPD12_1659 c831b25618262033a49e64a2d9034050 325 Gene3D G3DSA:1.10.287.130 120 169 4.5E-29 T 12-10-2018 NPD12_1659 c831b25618262033a49e64a2d9034050 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1659 c831b25618262033a49e64a2d9034050 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 325 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1659 c831b25618262033a49e64a2d9034050 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1659 c831b25618262033a49e64a2d9034050 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1659 c831b25618262033a49e64a2d9034050 325 SMART SM00387 216 325 1.2E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1659 c831b25618262033a49e64a2d9034050 325 Gene3D G3DSA:3.30.565.10 170 324 4.5E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1659 c831b25618262033a49e64a2d9034050 325 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 324 7.4E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1659 c831b25618262033a49e64a2d9034050 325 SUPERFAMILY SSF55874 176 324 1.14E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 819 1234 9.5E-90 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 415 629 1.8E-44 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:1.10.150.700 1089 1181 1.0E-33 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:1.10.150.700 1228 1279 1.4E-13 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 SUPERFAMILY SSF50249 237 312 2.06E-6 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:3.30.420.10 413 554 2.1E-46 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1432 401.973 T 12-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 SMART SM00481 333 400 5.1E-29 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Pfam PF11490 DNA polymerase III polC-type N-terminus II 89 200 4.3E-21 T 12-10-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 231 1430 0.0 T 12-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Pfam PF00929 Exonuclease 419 573 3.5E-38 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:1.10.100.20 988 1035 1.2E-57 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 SUPERFAMILY SSF53098 417 870 8.8E-104 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Pfam PF01336 OB-fold nucleic acid binding domain 238 306 2.8E-6 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:1.10.150.870 1280 1416 7.0E-53 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Pfam PF14579 Helix-hairpin-helix motif 1342 1424 4.3E-13 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:3.30.1900.20 966 1088 1.2E-57 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:2.40.50.140 222 319 4.1E-25 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:3.20.20.140 332 412 8.4E-27 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Gene3D G3DSA:3.20.20.140 557 796 1.4E-56 T 12-10-2018 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 Pfam PF02811 PHP domain 334 690 2.4E-51 T 12-10-2018 IPR004013 PHP domain GO:0003824 NPD12_2471 e4c94e84c42cc9f23b0918f10eb32517 1432 SMART SM00479 417 582 9.8E-52 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_2967 d56f66ed1fec8698ac2522c0630ff3d4 216 Pfam PF13346 ABC-2 family transporter protein 3 211 3.1E-36 T 12-10-2018 IPR025699 ABC-2 membrane transporter-like NPD12_114 8101101fb1fe5340491f63403007432a 193 SUPERFAMILY SSF53163 15 181 7.59E-52 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily NPD12_114 8101101fb1fe5340491f63403007432a 193 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 34 173 8.3E-68 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 NPD12_114 8101101fb1fe5340491f63403007432a 193 Pfam PF06866 Protein of unknown function (DUF1256) 14 171 5.7E-65 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 NPD12_2029 019fe6edcc7427b2e221ae2be942fdf3 54 Gene3D G3DSA:1.10.101.10 1 54 1.8E-14 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 NPD12_2029 019fe6edcc7427b2e221ae2be942fdf3 54 SUPERFAMILY SSF47090 1 50 7.06E-13 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_2029 019fe6edcc7427b2e221ae2be942fdf3 54 Pfam PF01471 Putative peptidoglycan binding domain 2 49 3.2E-11 T 12-10-2018 IPR002477 Peptidoglycan binding-like NPD12_615 7b7f5e7b57a530a06448a5a184382a39 242 Gene3D G3DSA:3.40.50.150 68 241 4.0E-29 T 12-10-2018 NPD12_615 7b7f5e7b57a530a06448a5a184382a39 242 Pfam PF13649 Methyltransferase domain 89 196 9.6E-19 T 12-10-2018 NPD12_615 7b7f5e7b57a530a06448a5a184382a39 242 SUPERFAMILY SSF53335 73 221 7.6E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 407 423 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 SUPERFAMILY SSF160443 712 788 1.31E-10 T 12-10-2018 IPR036063 Smr domain superfamily NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 SMART SM00534 325 510 5.7E-76 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 SMART SM00463 710 788 3.6E-16 T 12-10-2018 IPR002625 Smr domain NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 Gene3D G3DSA:3.40.50.300 291 595 3.1E-83 T 12-10-2018 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 Gene3D G3DSA:3.30.1370.110 702 788 2.3E-24 T 12-10-2018 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 TIGRFAM TIGR01069 mutS2: MutS2 family protein 2 788 1.6E-224 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 SUPERFAMILY SSF52540 289 510 1.39E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 Pfam PF00488 MutS domain V 329 509 2.3E-36 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 787 21.869 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 SUPERFAMILY SSF48334 63 287 2.09E-16 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 SMART SM00533 9 312 5.8E-22 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 PIRSF PIRSF005814 1 788 3.7E-268 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 NPD12_3231 c0dd809bf66e81d60fea52acd05fc7b3 788 Pfam PF01713 Smr domain 713 788 4.1E-22 T 12-10-2018 IPR002625 Smr domain NPD12_1789 ede3041b039294ad86375a5af158ca34 56 Gene3D G3DSA:1.10.10.10 1 54 1.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1789 ede3041b039294ad86375a5af158ca34 56 ProSitePatterns PS00622 LuxR-type HTH domain signature. 8 35 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1789 ede3041b039294ad86375a5af158ca34 56 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 24 36 2.4E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1789 ede3041b039294ad86375a5af158ca34 56 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 8 24 2.4E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1789 ede3041b039294ad86375a5af158ca34 56 SMART SM00421 1 48 3.6E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1789 ede3041b039294ad86375a5af158ca34 56 SUPERFAMILY SSF46894 1 53 5.1E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_1789 ede3041b039294ad86375a5af158ca34 56 Pfam PF00196 Bacterial regulatory proteins, luxR family 1 46 7.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_3738 49df53b65b3e2516bb953ef9bee0bfe1 63 Pfam PF14020 Protein of unknown function (DUF4236) 3 55 1.6E-21 T 12-10-2018 IPR025330 Domain of unknown function DUF4236 NPD12_2794 7701ef4c429b5f08979e871e8e93680a 354 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 345 1.3E-30 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 NPD12_2794 7701ef4c429b5f08979e871e8e93680a 354 SUPERFAMILY SSF53756 2 351 4.12E-96 T 12-10-2018 NPD12_2794 7701ef4c429b5f08979e871e8e93680a 354 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 353 30.392 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_2794 7701ef4c429b5f08979e871e8e93680a 354 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 141 3.2E-45 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_2794 7701ef4c429b5f08979e871e8e93680a 354 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 348 8.7E-85 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_2794 7701ef4c429b5f08979e871e8e93680a 354 Gene3D G3DSA:3.40.50.2000 177 338 2.6E-38 T 12-10-2018 NPD12_2794 7701ef4c429b5f08979e871e8e93680a 354 Gene3D G3DSA:3.40.50.2000 1 176 1.3E-61 T 12-10-2018 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 Pfam PF04963 Sigma-54 factor, core binding domain 96 282 7.0E-49 T 12-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 343 362 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 Gene3D G3DSA:1.10.10.1330 100 232 1.3E-23 T 12-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 Pfam PF04552 Sigma-54, DNA binding domain 296 456 2.0E-56 T 12-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 PIRSF PIRSF000774 1 457 5.0E-140 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 Gene3D G3DSA:1.10.10.60 398 455 8.1E-24 T 12-10-2018 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 436 443 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 PRINTS PR00045 Sigma-54 factor signature 167 184 5.0E-22 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 PRINTS PR00045 Sigma-54 factor signature 431 449 5.0E-22 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 PRINTS PR00045 Sigma-54 factor signature 355 367 5.0E-22 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 PRINTS PR00045 Sigma-54 factor signature 371 382 5.0E-22 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 50 1.8E-17 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_382 78ca5fb43e215ab1707166cd0876683f 457 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 455 3.6E-132 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 NPD12_3005 dd486dee9123ef9166a34800c115ee87 252 SUPERFAMILY SSF88697 2 70 1.29E-15 T 12-10-2018 IPR015947 PUA-like superfamily NPD12_3005 dd486dee9123ef9166a34800c115ee87 252 Gene3D G3DSA:3.40.1280.10 72 251 2.8E-61 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal NPD12_3005 dd486dee9123ef9166a34800c115ee87 252 PIRSF PIRSF015601 1 248 3.5E-68 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 NPD12_3005 dd486dee9123ef9166a34800c115ee87 252 Gene3D G3DSA:2.40.240.20 1 70 1.4E-20 T 12-10-2018 NPD12_3005 dd486dee9123ef9166a34800c115ee87 252 SUPERFAMILY SSF75217 72 248 6.98E-52 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases NPD12_3005 dd486dee9123ef9166a34800c115ee87 252 Pfam PF04452 RNA methyltransferase 17 243 1.7E-74 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 NPD12_3005 dd486dee9123ef9166a34800c115ee87 252 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 248 7.6E-64 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 SUPERFAMILY SSF55920 1 247 7.33E-87 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 166 184 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 Pfam PF00557 Metallopeptidase family M24 12 238 7.7E-50 T 12-10-2018 IPR000994 Peptidase M24 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 160 172 1.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 1.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 Gene3D G3DSA:3.90.230.10 1 248 3.4E-103 T 12-10-2018 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 5.7E-98 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_3617 b76c74782cddc6ceb4fc6dc6d667c2f1 249 Hamap MF_01974 Methionine aminopeptidase [map]. 2 249 41.21 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_2450 500c9703399e446329c1fdad4dc28f5f 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 83 1.9E-40 T 12-10-2018 IPR007347 Sporulation stage V, protein S NPD12_2450 500c9703399e446329c1fdad4dc28f5f 86 Gene3D G3DSA:3.30.110.20 1 86 1.2E-36 T 12-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 NPD12_2450 500c9703399e446329c1fdad4dc28f5f 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 4.0E-27 T 12-10-2018 IPR007347 Sporulation stage V, protein S NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 Gene3D G3DSA:1.10.390.10 409 565 1.1E-44 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 86 133 9.8E-8 T 12-10-2018 IPR011096 FTP domain NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 254 403 3.7E-40 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 SUPERFAMILY SSF55486 252 565 4.21E-74 T 12-10-2018 NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 Gene3D G3DSA:3.10.170.10 252 408 7.5E-39 T 12-10-2018 NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 Pfam PF03413 Peptidase propeptide and YPEB domain 149 213 2.5E-5 T 12-10-2018 IPR025711 PepSY domain NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 407 565 7.7E-48 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 395 411 1.6E-14 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 483 499 1.6E-14 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1693 e5474f8c85dc017b5bf6d17d49892273 573 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 416 427 1.6E-14 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 NPD12_1947 fea175a13a73b9ddb66d287211f1e01a 85 Gene3D G3DSA:2.30.30.100 2 71 5.3E-31 T 12-10-2018 NPD12_1947 fea175a13a73b9ddb66d287211f1e01a 85 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 66 4.9E-32 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 NPD12_1947 fea175a13a73b9ddb66d287211f1e01a 85 Pfam PF17209 Hfq protein 8 69 7.2E-33 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 NPD12_1947 fea175a13a73b9ddb66d287211f1e01a 85 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 66 30.053 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 NPD12_1947 fea175a13a73b9ddb66d287211f1e01a 85 SUPERFAMILY SSF50182 7 65 4.78E-24 T 12-10-2018 IPR010920 LSM domain superfamily NPD12_2295 1920c09e7efa9ce31d30601291d65f8d 468 Gene3D G3DSA:1.20.1250.20 1 467 1.2E-97 T 12-10-2018 NPD12_2295 1920c09e7efa9ce31d30601291d65f8d 468 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 243 461 3.1E-45 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 NPD12_2295 1920c09e7efa9ce31d30601291d65f8d 468 Pfam PF00854 POT family 231 429 2.8E-31 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_2295 1920c09e7efa9ce31d30601291d65f8d 468 Pfam PF00854 POT family 86 212 3.7E-14 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_2295 1920c09e7efa9ce31d30601291d65f8d 468 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 147 159 - T 12-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 NPD12_2295 1920c09e7efa9ce31d30601291d65f8d 468 SUPERFAMILY SSF103473 8 455 5.36E-39 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 Gene3D G3DSA:1.10.1020.10 63 161 8.0E-39 T 12-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 8 244 7.7E-20 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 56 69 7.1E-11 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 33 47 7.1E-11 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 8 24 7.1E-11 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 187 199 7.1E-11 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 PIRSF PIRSF000398 1 275 2.0E-58 T 12-10-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 SUPERFAMILY SSF53335 2 269 6.43E-50 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3024 91e5163b583109f1fdb0e080e5bc4e3f 286 Gene3D G3DSA:3.40.50.150 6 244 8.0E-39 T 12-10-2018 NPD12_2618 5e91b4ef0cf4a65fa20be879a78fbcd2 302 Pfam PF03547 Membrane transport protein 157 297 7.8E-16 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 NPD12_2618 5e91b4ef0cf4a65fa20be879a78fbcd2 302 Pfam PF03547 Membrane transport protein 5 146 3.1E-19 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 NPD12_2618 5e91b4ef0cf4a65fa20be879a78fbcd2 302 Gene3D G3DSA:1.20.1530.20 163 302 6.1E-7 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_3591 d2658cd52079fa06f24acd326a868677 287 Gene3D G3DSA:3.50.50.60 7 278 1.6E-68 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 3.9E-27 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 3.9E-27 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 137 3.9E-27 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 264 3.9E-27 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 59 69 3.9E-27 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 3.9E-27 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 Gene3D G3DSA:3.50.50.60 115 220 1.6E-68 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3591 d2658cd52079fa06f24acd326a868677 287 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 268 2.2E-21 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 SUPERFAMILY SSF51905 3 284 2.3E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 258 3.3E-16 T 12-10-2018 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 3.3E-16 T 12-10-2018 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.3E-16 T 12-10-2018 NPD12_3591 d2658cd52079fa06f24acd326a868677 287 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 3.3E-16 T 12-10-2018 NPD12_2739 d2d921462ba982d9144a87812ca3b454 58 Pfam PF14070 Putative motility protein 3 56 4.5E-19 T 12-10-2018 IPR025906 Putative motility protein NPD12_234 28fd2f9a3e6cb9a16b3d70109615d058 264 SUPERFAMILY SSF51556 4 258 2.67E-87 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_234 28fd2f9a3e6cb9a16b3d70109615d058 264 PIRSF PIRSF005902 1 260 2.4E-86 T 12-10-2018 IPR001130 TatD family GO:0016788 NPD12_234 28fd2f9a3e6cb9a16b3d70109615d058 264 Gene3D G3DSA:3.20.20.140 1 258 3.0E-100 T 12-10-2018 NPD12_234 28fd2f9a3e6cb9a16b3d70109615d058 264 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 6 256 2.5E-86 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 NPD12_234 28fd2f9a3e6cb9a16b3d70109615d058 264 Pfam PF01026 TatD related DNase 7 256 7.3E-80 T 12-10-2018 IPR001130 TatD family GO:0016788 NPD12_234 28fd2f9a3e6cb9a16b3d70109615d058 264 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 192 208 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 NPD12_3531 48d2e506010c8180bd057850c74fd744 445 Pfam PF01933 Uncharacterised protein family UPF0052 104 392 1.6E-111 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 NPD12_3531 48d2e506010c8180bd057850c74fd744 445 Gene3D G3DSA:3.40.50.12300 99 427 2.0E-129 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily NPD12_3531 48d2e506010c8180bd057850c74fd744 445 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 104 414 9.6E-121 T 12-10-2018 IPR010119 Gluconeogenesis factor NPD12_3531 48d2e506010c8180bd057850c74fd744 445 SUPERFAMILY SSF142338 101 412 7.46E-103 T 12-10-2018 NPD12_3531 48d2e506010c8180bd057850c74fd744 445 Hamap MF_00973 Gluconeogenesis factor. 100 417 35.201 T 12-10-2018 IPR010119 Gluconeogenesis factor NPD12_223 78ca4c48eec84cfc43598f763beca405 403 Hamap MF_00242 Arginine deiminase [arcA]. 4 402 45.058 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 PRINTS PR01466 Bacterial arginine deiminase signature 381 399 2.3E-58 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 PRINTS PR01466 Bacterial arginine deiminase signature 338 355 2.3E-58 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 PRINTS PR01466 Bacterial arginine deiminase signature 175 190 2.3E-58 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 PRINTS PR01466 Bacterial arginine deiminase signature 358 372 2.3E-58 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 PRINTS PR01466 Bacterial arginine deiminase signature 5 25 2.3E-58 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 PRINTS PR01466 Bacterial arginine deiminase signature 147 165 2.3E-58 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 Gene3D G3DSA:3.75.10.10 8 397 5.9E-154 T 12-10-2018 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 PIRSF PIRSF006356 1 402 3.3E-163 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 Gene3D G3DSA:1.10.3930.10 71 147 5.9E-154 T 12-10-2018 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 TIGRFAM TIGR01078 arcA: arginine deiminase 7 401 8.1E-160 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 SUPERFAMILY SSF55909 5 402 1.18E-128 T 12-10-2018 NPD12_223 78ca4c48eec84cfc43598f763beca405 403 Pfam PF02274 Amidinotransferase 21 399 1.5E-99 T 12-10-2018 NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 Gene3D G3DSA:1.10.357.10 62 204 1.5E-16 T 12-10-2018 NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 Gene3D G3DSA:1.10.10.60 14 61 3.1E-14 T 12-10-2018 NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 SUPERFAMILY SSF46689 6 78 1.47E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 Pfam PF13305 WHG domain 94 180 3.2E-10 T 12-10-2018 IPR025996 WHG domain NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 7.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_1213 7c5553b315d8e2af7d1734785581ee1e 204 SUPERFAMILY SSF48498 85 203 5.48E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily NPD12_1204 17994a38faa050d1b6b33a7947580412 394 SUPERFAMILY SSF53383 25 392 7.07E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1204 17994a38faa050d1b6b33a7947580412 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 NPD12_1204 17994a38faa050d1b6b33a7947580412 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 99 119 2.3E-11 T 12-10-2018 NPD12_1204 17994a38faa050d1b6b33a7947580412 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 236 260 2.3E-11 T 12-10-2018 NPD12_1204 17994a38faa050d1b6b33a7947580412 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 167 191 2.3E-11 T 12-10-2018 NPD12_1204 17994a38faa050d1b6b33a7947580412 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 121 142 2.3E-11 T 12-10-2018 NPD12_1204 17994a38faa050d1b6b33a7947580412 394 Pfam PF00155 Aminotransferase class I and II 35 381 4.6E-52 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1204 17994a38faa050d1b6b33a7947580412 394 Gene3D G3DSA:3.40.640.10 69 300 8.1E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1204 17994a38faa050d1b6b33a7947580412 394 Gene3D G3DSA:3.90.1150.10 16 377 8.1E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1020 1594f0583a7ffbd720308efb87b22619 373 Gene3D G3DSA:3.90.1150.10 251 373 1.6E-41 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1020 1594f0583a7ffbd720308efb87b22619 373 PIRSF PIRSF000390 3 373 2.7E-103 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_1020 1594f0583a7ffbd720308efb87b22619 373 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 367 2.3E-115 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_1020 1594f0583a7ffbd720308efb87b22619 373 SUPERFAMILY SSF53383 17 372 1.0E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1020 1594f0583a7ffbd720308efb87b22619 373 Gene3D G3DSA:3.40.640.10 1 249 3.3E-85 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2040 f0a22962f5878b83ad1f0941ffcf535a 298 SUPERFAMILY SSF52317 21 291 4.96E-83 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2040 f0a22962f5878b83ad1f0941ffcf535a 298 Pfam PF04204 Homoserine O-succinyltransferase 3 289 1.5E-113 T 12-10-2018 IPR033752 MetA family NPD12_2040 f0a22962f5878b83ad1f0941ffcf535a 298 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 49 288 1.0E-77 T 12-10-2018 NPD12_2040 f0a22962f5878b83ad1f0941ffcf535a 298 PIRSF PIRSF000450 1 292 2.3E-117 T 12-10-2018 IPR033752 MetA family NPD12_2040 f0a22962f5878b83ad1f0941ffcf535a 298 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 289 1.1E-110 T 12-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 NPD12_2040 f0a22962f5878b83ad1f0941ffcf535a 298 Gene3D G3DSA:3.40.50.880 1 295 3.1E-111 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2040 f0a22962f5878b83ad1f0941ffcf535a 298 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 30 298 37.708 T 12-10-2018 IPR033752 MetA family NPD12_1260 ea3ab9c736c84ca4cf7300326e0f807d 116 SUPERFAMILY SSF52833 2 111 4.16E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_1260 ea3ab9c736c84ca4cf7300326e0f807d 116 Gene3D G3DSA:3.40.30.10 1 112 2.6E-24 T 12-10-2018 NPD12_1260 ea3ab9c736c84ca4cf7300326e0f807d 116 Pfam PF03960 ArsC family 44 110 1.8E-8 T 12-10-2018 IPR006660 Arsenate reductase-like NPD12_302 4e0fbe651409075d76ed38ad8fa21f23 344 Pfam PF00953 Glycosyl transferase family 4 76 233 4.3E-43 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 NPD12_302 4e0fbe651409075d76ed38ad8fa21f23 344 ProSitePatterns PS01348 MraY family signature 2. 153 164 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 Pfam PF01676 Metalloenzyme superfamily 4 497 8.0E-81 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 4 508 5.7E-227 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 SUPERFAMILY SSF64158 77 307 4.71E-87 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 Gene3D G3DSA:3.40.1450.10 77 309 1.3E-232 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 295 6.3E-89 T 12-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 PIRSF PIRSF001492 1 509 3.3E-215 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 509 51.433 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 Gene3D G3DSA:3.40.720.10 5 508 1.3E-232 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 NPD12_387 f7fa81d17251b27206c71330b5f62e13 509 SUPERFAMILY SSF53649 3 508 1.7E-77 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 NPD12_2380 dda9953520b563a28ece49c45aaa5cfb 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 225 24.097 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 NPD12_2380 dda9953520b563a28ece49c45aaa5cfb 227 Gene3D G3DSA:3.40.50.300 2 217 1.3E-48 T 12-10-2018 NPD12_2380 dda9953520b563a28ece49c45aaa5cfb 227 Pfam PF13500 AAA domain 3 205 1.0E-33 T 12-10-2018 NPD12_2380 dda9953520b563a28ece49c45aaa5cfb 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 179 4.4E-38 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 NPD12_2380 dda9953520b563a28ece49c45aaa5cfb 227 SUPERFAMILY SSF52540 1 218 1.15E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2380 dda9953520b563a28ece49c45aaa5cfb 227 PIRSF PIRSF006755 1 222 9.4E-52 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 Pfam PF00232 Glycosyl hydrolase family 1 2 465 4.0E-141 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 384 395 9.6E-17 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 442 9.6E-17 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 405 422 9.6E-17 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 359 367 9.6E-17 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 294 308 9.6E-17 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 SUPERFAMILY SSF51445 2 465 1.65E-159 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 Gene3D G3DSA:3.20.20.80 3 468 3.1E-152 T 12-10-2018 NPD12_1388 dd9b108fb7a765e4ba7959e065ebda13 481 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 359 367 - T 12-10-2018 IPR018120 Glycoside hydrolase family 1, active site NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 SUPERFAMILY SSF52540 5 247 1.77E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 Gene3D G3DSA:2.40.50.140 288 328 3.9E-11 T 12-10-2018 NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 359 1.4E-122 T 12-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 SMART SM00382 32 215 6.7E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 SUPERFAMILY SSF50331 240 359 4.99E-11 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 Pfam PF08402 TOBE domain 281 359 2.5E-8 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 Gene3D G3DSA:3.40.50.300 5 225 1.3E-67 T 12-10-2018 NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 Pfam PF00005 ABC transporter 24 165 9.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_736 e7502bb53739fbdf1cb4deb30e0dfacc 360 Gene3D G3DSA:2.40.50.940 226 287 3.9E-11 T 12-10-2018 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 151 3.3E-11 T 12-10-2018 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 626 26.505 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Gene3D G3DSA:3.30.565.10 1 225 8.3E-72 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PIRSF PIRSF002583 1 626 2.0E-201 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 SUPERFAMILY SSF54211 236 488 3.11E-80 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Gene3D G3DSA:3.30.230.80 235 407 1.9E-54 T 12-10-2018 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Gene3D G3DSA:1.20.120.790 495 626 1.5E-34 T 12-10-2018 IPR037196 HSP90, C-terminal domain NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 SUPERFAMILY SSF110942 511 625 4.71E-30 T 12-10-2018 IPR037196 HSP90, C-terminal domain NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PRINTS PR00775 90kDa heat shock protein signature 2 22 4.5E-55 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PRINTS PR00775 90kDa heat shock protein signature 72 89 4.5E-55 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PRINTS PR00775 90kDa heat shock protein signature 115 137 4.5E-55 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PRINTS PR00775 90kDa heat shock protein signature 23 45 4.5E-55 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PRINTS PR00775 90kDa heat shock protein signature 165 182 4.5E-55 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PRINTS PR00775 90kDa heat shock protein signature 188 206 4.5E-55 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 PRINTS PR00775 90kDa heat shock protein signature 90 107 4.5E-55 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Gene3D G3DSA:3.40.50.11260 408 494 1.4E-28 T 12-10-2018 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 SUPERFAMILY SSF55874 1 212 7.39E-61 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Pfam PF00183 Hsp90 protein 184 230 1.1E-7 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 NPD12_2147 0ed43da0f0af9e76e4a7f45481d6a3df 626 Pfam PF00183 Hsp90 protein 217 626 2.1E-110 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 NPD12_105 b48581c832fb9841519b63039df35f0c 80 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 80 3.0E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 Gene3D G3DSA:4.10.640.10 2 80 2.3E-32 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 Pfam PF01084 Ribosomal protein S18 25 75 1.9E-28 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 3.6E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 3.6E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 3.6E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 3.6E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 TIGRFAM TIGR00165 S18: ribosomal protein bS18 13 79 5.9E-34 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 80 22.89 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_105 b48581c832fb9841519b63039df35f0c 80 SUPERFAMILY SSF46911 7 79 4.84E-30 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 685 17.235 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 191 346 4.5E-36 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 SUPERFAMILY SSF50447 359 442 6.09E-28 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 SUPERFAMILY SSF52156 465 594 1.16E-38 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Gene3D G3DSA:2.40.30.10 589 686 1.5E-32 T 12-10-2018 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Pfam PF00009 Elongation factor Tu GTP binding domain 189 347 3.3E-35 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 107 686 4.4E-261 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 110 158 5.8E-11 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 49 1.4E-15 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Gene3D G3DSA:3.40.50.300 184 358 2.2E-74 T 12-10-2018 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Pfam PF11987 Translation-initiation factor 2 472 577 2.5E-38 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Gene3D G3DSA:1.10.10.2480 1 68 3.7E-22 T 12-10-2018 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 SUPERFAMILY SSF50447 589 685 5.61E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Gene3D G3DSA:3.40.50.10050 481 588 2.4E-39 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 ProSitePatterns PS01176 Initiation factor 2 signature. 638 660 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 SUPERFAMILY SSF52540 171 359 6.47E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2466 ef76afd728435ebfb9d11f161cf6daad 688 Gene3D G3DSA:2.40.30.10 359 476 1.7E-43 T 12-10-2018 NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 118 151 8.6E-9 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 186 215 6.3E-10 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 254 288 3.8E-9 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 288 316 2.3E-8 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 85 118 4.0E-11 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 50 83 1.9E-10 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 16 48 0.001 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 220 254 5.3E-10 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 Pfam PF14903 WG containing repeat 153 186 5.8E-12 T 12-10-2018 IPR032774 WG containing repeat NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 SUPERFAMILY SSF69360 5 103 3.77E-6 T 12-10-2018 NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 SUPERFAMILY SSF69360 217 331 2.59E-9 T 12-10-2018 NPD12_1905 40513404c0798ca11b2d34de0a9ab307 337 SUPERFAMILY SSF69360 81 202 3.34E-14 T 12-10-2018 NPD12_472 ea6c5d8a1250e7fa2c00cfea3f37b75e 312 SUPERFAMILY SSF53807 44 302 6.28E-47 T 12-10-2018 NPD12_472 ea6c5d8a1250e7fa2c00cfea3f37b75e 312 Gene3D G3DSA:3.40.50.1980 152 311 1.7E-51 T 12-10-2018 NPD12_472 ea6c5d8a1250e7fa2c00cfea3f37b75e 312 Pfam PF01497 Periplasmic binding protein 80 283 1.4E-27 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_472 ea6c5d8a1250e7fa2c00cfea3f37b75e 312 Gene3D G3DSA:3.40.50.1980 41 151 1.7E-25 T 12-10-2018 NPD12_110 bf646720f6a0c7ebdd24942a19a9cde4 289 SUPERFAMILY SSF82689 191 286 4.05E-16 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 NPD12_110 bf646720f6a0c7ebdd24942a19a9cde4 289 SUPERFAMILY SSF50182 124 186 5.89E-15 T 12-10-2018 IPR010920 LSM domain superfamily NPD12_110 bf646720f6a0c7ebdd24942a19a9cde4 289 Gene3D G3DSA:3.30.70.100 190 278 4.3E-19 T 12-10-2018 NPD12_110 bf646720f6a0c7ebdd24942a19a9cde4 289 Gene3D G3DSA:2.30.30.60 140 189 1.7E-20 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily NPD12_110 bf646720f6a0c7ebdd24942a19a9cde4 289 SUPERFAMILY SSF82861 37 123 1.31E-5 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 NPD12_110 bf646720f6a0c7ebdd24942a19a9cde4 289 Pfam PF00924 Mechanosensitive ion channel 84 280 1.0E-37 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 NPD12_2650 d1b388d8c29d38734aacd360c019ba10 230 Gene3D G3DSA:3.20.20.140 4 197 1.8E-50 T 12-10-2018 NPD12_2650 d1b388d8c29d38734aacd360c019ba10 230 Gene3D G3DSA:1.10.150.650 51 122 1.8E-50 T 12-10-2018 NPD12_2650 d1b388d8c29d38734aacd360c019ba10 230 SUPERFAMILY SSF89550 3 204 8.83E-23 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_1134 36928ee847ae301f4336482a55e835f4 373 Gene3D G3DSA:3.40.50.11220 4 157 1.2E-35 T 12-10-2018 NPD12_1134 36928ee847ae301f4336482a55e835f4 373 Gene3D G3DSA:3.30.420.180 246 373 8.8E-27 T 12-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 NPD12_1134 36928ee847ae301f4336482a55e835f4 373 Pfam PF01890 Cobalamin synthesis G C-terminus 255 370 3.6E-28 T 12-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 NPD12_1134 36928ee847ae301f4336482a55e835f4 373 SUPERFAMILY SSF159664 248 372 3.27E-32 T 12-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 NPD12_1134 36928ee847ae301f4336482a55e835f4 373 Pfam PF11761 Cobalamin biosynthesis central region 168 230 3.0E-6 T 12-10-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 NPD12_1134 36928ee847ae301f4336482a55e835f4 373 Pfam PF11760 Cobalamin synthesis G N-terminal 82 162 2.1E-37 T 12-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 NPD12_1134 36928ee847ae301f4336482a55e835f4 373 SUPERFAMILY SSF159672 8 262 8.37E-58 T 12-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 Pfam PF01926 50S ribosome-binding GTPase 160 283 7.9E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 SUPERFAMILY SSF102741 357 422 1.83E-18 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 SUPERFAMILY SSF52540 149 337 1.44E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 325 4.8E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 Gene3D G3DSA:2.40.240.60 355 423 7.0E-15 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 Hamap MF_01454 GTPase Obg [obg]. 1 331 47.478 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 3.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 3.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 3.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 3.7E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 Pfam PF01018 GTP1/OBG 3 157 2.3E-61 T 12-10-2018 IPR006169 GTP1/OBG domain NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 PIRSF PIRSF002401 1 372 1.3E-139 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 357 422 1.3E-22 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 SUPERFAMILY SSF82051 2 157 4.58E-56 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 Pfam PF09269 Domain of unknown function (DUF1967) 356 422 1.4E-21 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 Gene3D G3DSA:2.70.210.12 1 157 3.5E-60 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 Gene3D G3DSA:3.40.50.300 158 338 1.8E-54 T 12-10-2018 NPD12_3092 ef3dbd55594a5e92f0e73f928c5f9bbb 424 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 330 1.6E-142 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 Gene3D G3DSA:2.30.170.50 1 69 1.5E-32 T 12-10-2018 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 PRINTS PR01249 Ribosomal protein L31 signature 31 46 1.0E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 PRINTS PR01249 Ribosomal protein L31 signature 46 64 1.0E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 1.5E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 28.868 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 Pfam PF01197 Ribosomal protein L31 1 65 1.1E-32 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_289 ecd50257711350dd1d2bdf446f9d6c18 72 SUPERFAMILY SSF143800 1 66 7.06E-27 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_925 3d9c8c1f8975b168bc5c5aacf8687560 419 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 306 373 4.5E-13 T 12-10-2018 IPR006343 DnaD domain NPD12_925 3d9c8c1f8975b168bc5c5aacf8687560 419 Pfam PF07261 Replication initiation and membrane attachment 308 375 2.1E-15 T 12-10-2018 IPR006343 DnaD domain NPD12_925 3d9c8c1f8975b168bc5c5aacf8687560 419 SUPERFAMILY SSF158499 307 368 9.02E-14 T 12-10-2018 IPR034829 DnaD-like domain superfamily NPD12_925 3d9c8c1f8975b168bc5c5aacf8687560 419 Gene3D G3DSA:1.10.10.630 300 374 5.1E-13 T 12-10-2018 IPR034829 DnaD-like domain superfamily NPD12_1557 6d3fd0820304bd6e006613322ebae9e0 118 Gene3D G3DSA:3.30.420.130 1 106 3.9E-28 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily NPD12_1557 6d3fd0820304bd6e006613322ebae9e0 118 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 98 4.0E-23 T 12-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis NPD12_1557 6d3fd0820304bd6e006613322ebae9e0 118 SUPERFAMILY SSF53146 1 118 1.44E-32 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily NPD12_2480 d1626496cbfaed5a595df3d1dcaccec0 184 Pfam PF01765 Ribosome recycling factor 20 182 2.4E-66 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 NPD12_2480 d1626496cbfaed5a595df3d1dcaccec0 184 Gene3D G3DSA:3.30.1360.40 31 105 9.8E-68 T 12-10-2018 NPD12_2480 d1626496cbfaed5a595df3d1dcaccec0 184 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 184 27.668 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 NPD12_2480 d1626496cbfaed5a595df3d1dcaccec0 184 SUPERFAMILY SSF55194 3 182 3.4E-70 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 NPD12_2480 d1626496cbfaed5a595df3d1dcaccec0 184 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 184 2.4E-69 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 NPD12_2480 d1626496cbfaed5a595df3d1dcaccec0 184 Gene3D G3DSA:1.10.132.20 12 181 9.8E-68 T 12-10-2018 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 Gene3D G3DSA:3.30.450.20 210 333 4.5E-10 T 12-10-2018 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 SUPERFAMILY SSF55874 418 587 2.23E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 584 3.3E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 SMART SM00387 475 587 1.2E-35 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 526 5.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 584 5.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 540 5.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 565 5.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 Pfam PF13188 PAS domain 227 280 3.2E-4 T 12-10-2018 IPR000014 PAS domain NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 Gene3D G3DSA:3.30.565.10 436 591 2.9E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 222 340 4.8E-11 T 12-10-2018 IPR000014 PAS domain NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 SUPERFAMILY SSF47384 350 429 1.26E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 Pfam PF00512 His Kinase A (phospho-acceptor) domain 363 429 3.2E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 SMART SM00388 361 429 1.1E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 SUPERFAMILY SSF55785 213 333 2.28E-8 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_500 17027ac0f073f0c8c332afdd0ba91fca 615 Gene3D G3DSA:1.10.287.130 352 434 4.9E-21 T 12-10-2018 NPD12_818 22799e5dff18f774c1f282629bdf629b 145 SMART SM00347 24 124 1.3E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_818 22799e5dff18f774c1f282629bdf629b 145 Gene3D G3DSA:1.10.10.10 4 140 1.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_818 22799e5dff18f774c1f282629bdf629b 145 SUPERFAMILY SSF46785 8 139 6.07E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_818 22799e5dff18f774c1f282629bdf629b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 8.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_818 22799e5dff18f774c1f282629bdf629b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 8.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_818 22799e5dff18f774c1f282629bdf629b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 8.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1072 15a8f5db765340d5a68697e72f63c128 50 Gene3D G3DSA:3.40.50.360 1 50 1.6E-8 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1072 15a8f5db765340d5a68697e72f63c128 50 SUPERFAMILY SSF52218 1 45 2.79E-10 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1072 15a8f5db765340d5a68697e72f63c128 50 Pfam PF03358 NADPH-dependent FMN reductase 1 45 1.1E-5 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_976 9941b0481601415075c891deffaa15c3 341 SUPERFAMILY SSF81345 5 333 1.24E-70 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_976 9941b0481601415075c891deffaa15c3 341 Gene3D G3DSA:1.10.3470.10 6 340 9.6E-84 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_976 9941b0481601415075c891deffaa15c3 341 Pfam PF01032 FecCD transport family 19 333 2.2E-85 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_2174 8323cf5cdb269ebff132a1476cf6deac 383 Gene3D G3DSA:3.90.1150.10 25 381 6.7E-119 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_2174 8323cf5cdb269ebff132a1476cf6deac 383 Pfam PF00155 Aminotransferase class I and II 30 379 7.1E-69 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_2174 8323cf5cdb269ebff132a1476cf6deac 383 Gene3D G3DSA:3.40.640.10 49 286 6.7E-119 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2174 8323cf5cdb269ebff132a1476cf6deac 383 SUPERFAMILY SSF53383 18 383 7.26E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2301 0df312a2e416566f60810876ae9aebf2 306 SUPERFAMILY SSF54506 4 301 1.36E-63 T 12-10-2018 NPD12_2301 0df312a2e416566f60810876ae9aebf2 306 Pfam PF02567 Phenazine biosynthesis-like protein 9 296 2.8E-63 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 NPD12_2301 0df312a2e416566f60810876ae9aebf2 306 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 299 1.1E-71 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 NPD12_2301 0df312a2e416566f60810876ae9aebf2 306 PIRSF PIRSF016184 1 303 1.3E-81 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 NPD12_2301 0df312a2e416566f60810876ae9aebf2 306 Gene3D G3DSA:3.10.310.10 128 292 4.2E-88 T 12-10-2018 NPD12_2301 0df312a2e416566f60810876ae9aebf2 306 Gene3D G3DSA:3.10.310.10 8 294 4.2E-88 T 12-10-2018 NPD12_1547 a0615de31fb3edfdede3caa8d0648d27 698 Pfam PF03170 Bacterial cellulose synthase subunit 34 600 2.8E-104 T 12-10-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 NPD12_1547 a0615de31fb3edfdede3caa8d0648d27 698 Gene3D G3DSA:2.60.120.260 326 461 4.1E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_1547 a0615de31fb3edfdede3caa8d0648d27 698 Gene3D G3DSA:2.60.120.260 25 158 6.3E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_3207 e8df1b6d7ca3ef095463744a0c3de114 410 Pfam PF04932 O-Antigen ligase 204 338 1.6E-17 T 12-10-2018 IPR007016 O-antigen ligase-related NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Hamap MF_00054_B Elongation factor G [fusA]. 7 688 112.49 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 SUPERFAMILY SSF52540 7 281 1.4E-111 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 SMART SM00838 597 684 7.4E-59 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Gene3D G3DSA:2.40.30.10 292 404 2.4E-43 T 12-10-2018 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 SUPERFAMILY SSF54980 600 687 4.8E-31 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 SUPERFAMILY SSF54211 481 595 5.56E-41 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Pfam PF14492 Elongation Factor G, domain II 403 477 1.3E-32 T 12-10-2018 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 SUPERFAMILY SSF50447 264 403 3.28E-35 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Gene3D G3DSA:3.30.70.870 405 482 1.1E-30 T 12-10-2018 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 TIGRFAM TIGR00484 EF-G: translation elongation factor G 4 689 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Pfam PF00679 Elongation factor G C-terminus 597 683 2.0E-31 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Pfam PF03764 Elongation factor G, domain IV 478 594 1.1E-45 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Pfam PF03144 Elongation factor Tu domain 2 323 390 2.7E-15 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 PRINTS PR00315 GTP-binding elongation factor signature 13 26 1.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 PRINTS PR00315 GTP-binding elongation factor signature 59 67 1.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 181 3.4E-38 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 SMART SM00889 479 595 1.9E-68 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 SUPERFAMILY SSF54980 401 479 7.55E-24 T 12-10-2018 IPR035647 EF-G domain III/V-like NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Gene3D G3DSA:3.30.70.240 601 671 1.3E-90 T 12-10-2018 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Gene3D G3DSA:3.30.230.10 483 684 1.3E-90 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Pfam PF00009 Elongation factor Tu GTP binding domain 10 281 1.3E-68 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3642 4b952474fa026c5347a51f8bdee911a0 689 Gene3D G3DSA:3.40.50.300 3 291 3.9E-112 T 12-10-2018 NPD12_1232 bc4ca768817bbc7ec6f6cf45c9f60cd1 78 Pfam PF09851 Short C-terminal domain 51 74 2.9E-6 T 12-10-2018 IPR018649 SHOCT domain NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 SUPERFAMILY SSF55821 187 433 3.36E-43 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 PIRSF PIRSF006256 10 801 6.5E-268 T 12-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 ProSitePatterns PS00150 Acylphosphatase signature 1. 19 29 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Pfam PF01300 Telomere recombination 252 427 2.3E-52 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Pfam PF00708 Acylphosphatase 17 98 3.8E-19 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Gene3D G3DSA:3.30.420.360 428 789 5.5E-125 T 12-10-2018 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Pfam PF07503 HypF finger 117 150 1.3E-12 T 12-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Pfam PF07503 HypF finger 167 199 1.1E-12 T 12-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 207 789 3.2E-159 T 12-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Gene3D G3DSA:3.90.870.50 17 405 9.8E-139 T 12-10-2018 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 SUPERFAMILY SSF54975 11 99 1.7E-22 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Gene3D G3DSA:3.30.110.120 296 414 9.8E-139 T 12-10-2018 NPD12_1986 3d14792e37f7fc742fbe169a83db31ec 812 Gene3D G3DSA:3.30.420.350 523 777 5.5E-125 T 12-10-2018 NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 280 1.0E-60 T 12-10-2018 IPR000150 Cof family GO:0016787 NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 SUPERFAMILY SSF56784 2 284 3.41E-66 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 Gene3D G3DSA:3.30.1240.10 81 209 7.8E-85 T 12-10-2018 NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 ProSitePatterns PS01229 Hypothetical cof family signature 2. 234 256 - T 12-10-2018 NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 280 2.5E-65 T 12-10-2018 NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 253 1.1E-25 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 12-10-2018 NPD12_1855 23b28045ffb244e6e2103e7e99f72bcd 285 Gene3D G3DSA:3.40.50.1000 2 277 7.8E-85 T 12-10-2018 IPR023214 HAD superfamily NPD12_2530 fb73671afa6f0bd8d97487940e34dc8d 372 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 61 3.0E-12 T 12-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain NPD12_2530 fb73671afa6f0bd8d97487940e34dc8d 372 Gene3D G3DSA:3.40.50.11540 89 237 3.6E-18 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2530 fb73671afa6f0bd8d97487940e34dc8d 372 SUPERFAMILY SSF142019 42 245 1.44E-50 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2530 fb73671afa6f0bd8d97487940e34dc8d 372 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 85 227 3.5E-43 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2530 fb73671afa6f0bd8d97487940e34dc8d 372 TIGRFAM TIGR04481 PR_assoc_PrdC: proline reductase-associated electron transfer protein PrdC 5 371 1.4E-162 T 12-10-2018 IPR031001 Proline reductase-associated electron transfer protein PrdC NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 Gene3D G3DSA:3.30.70.20 134 193 1.4E-14 T 12-10-2018 NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 SUPERFAMILY SSF46548 136 262 3.92E-17 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 Pfam PF00037 4Fe-4S binding domain 239 261 3.3E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 Pfam PF00037 4Fe-4S binding domain 166 187 1.6E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 4 194 29.77 T 12-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 Gene3D G3DSA:3.30.70.20 211 263 2.7E-13 T 12-10-2018 NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 Gene3D G3DSA:3.20.20.20 36 104 1.6E-12 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 246 257 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 2 96 6.7E-25 T 12-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 NPD12_537 2d45c5ec5ac77bcdf46096c04b0e3fa0 277 Pfam PF04060 Putative Fe-S cluster 44 76 2.5E-13 T 12-10-2018 IPR007202 4Fe-4S domain GO:0051536 NPD12_3223 fde8e2ed2fe3357c39967659f07c379b 358 SUPERFAMILY SSF48452 223 344 1.52E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3223 fde8e2ed2fe3357c39967659f07c379b 358 Gene3D G3DSA:1.25.40.10 77 354 9.1E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3223 fde8e2ed2fe3357c39967659f07c379b 358 Pfam PF00515 Tetratricopeptide repeat 246 274 6.6E-7 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 NPD12_3223 fde8e2ed2fe3357c39967659f07c379b 358 Pfam PF13181 Tetratricopeptide repeat 282 309 0.076 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3223 fde8e2ed2fe3357c39967659f07c379b 358 SMART SM00028 278 311 1.8 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3223 fde8e2ed2fe3357c39967659f07c379b 358 SMART SM00028 312 344 22.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3223 fde8e2ed2fe3357c39967659f07c379b 358 SMART SM00028 244 277 1.2E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_2282 380a785676479c78163fccf120b8fe5e 379 Pfam PF01761 3-dehydroquinate synthase 82 339 1.2E-72 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 NPD12_2282 380a785676479c78163fccf120b8fe5e 379 Gene3D G3DSA:3.40.50.1970 18 186 1.8E-44 T 12-10-2018 NPD12_2282 380a785676479c78163fccf120b8fe5e 379 SUPERFAMILY SSF56796 29 359 3.14E-76 T 12-10-2018 NPD12_2282 380a785676479c78163fccf120b8fe5e 379 Gene3D G3DSA:1.20.1090.10 189 379 1.1E-51 T 12-10-2018 NPD12_2282 380a785676479c78163fccf120b8fe5e 379 PIRSF PIRSF001455 36 379 2.0E-95 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 NPD12_3 c30be67b7bf65346ca5c96407dd7ea87 79 Gene3D G3DSA:3.10.290.10 1 79 8.9E-23 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_3 c30be67b7bf65346ca5c96407dd7ea87 79 SMART SM00363 1 61 3.7E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3 c30be67b7bf65346ca5c96407dd7ea87 79 Pfam PF01479 S4 domain 1 46 6.7E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3 c30be67b7bf65346ca5c96407dd7ea87 79 PIRSF PIRSF038881 1 79 1.5E-30 T 12-10-2018 IPR025490 RNA-binding protein, HP1423 type NPD12_3 c30be67b7bf65346ca5c96407dd7ea87 79 SUPERFAMILY SSF55174 2 76 9.42E-19 T 12-10-2018 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 PRINTS PR00988 Uridine kinase signature 135 145 1.3E-35 T 12-10-2018 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 PRINTS PR00988 Uridine kinase signature 4 21 1.3E-35 T 12-10-2018 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 PRINTS PR00988 Uridine kinase signature 171 184 1.3E-35 T 12-10-2018 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 PRINTS PR00988 Uridine kinase signature 149 160 1.3E-35 T 12-10-2018 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 PRINTS PR00988 Uridine kinase signature 34 45 1.3E-35 T 12-10-2018 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 PRINTS PR00988 Uridine kinase signature 79 94 1.3E-35 T 12-10-2018 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 SUPERFAMILY SSF52540 2 196 3.53E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 TIGRFAM TIGR00235 udk: uridine kinase 4 204 6.1E-89 T 12-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 Hamap MF_00551 Uridine kinase [udk]. 1 205 41.411 T 12-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 191 1.1E-43 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 NPD12_2600 fa383e43d488d0ddf5fbe96039342b30 206 Gene3D G3DSA:3.40.50.300 1 206 2.2E-68 T 12-10-2018 NPD12_3790 1655d315648a0efcdda8309e642dbb12 388 Pfam PF04865 Baseplate J-like protein 77 301 1.3E-30 T 12-10-2018 IPR006949 Baseplate protein J-like NPD12_3418 5387dc73d5a3e7a6d308a56704b049f1 407 Gene3D G3DSA:3.40.50.11900 297 406 4.3E-5 T 12-10-2018 NPD12_3418 5387dc73d5a3e7a6d308a56704b049f1 407 Gene3D G3DSA:3.40.50.11890 36 179 4.4E-9 T 12-10-2018 NPD12_3418 5387dc73d5a3e7a6d308a56704b049f1 407 Gene3D G3DSA:1.20.1270.370 18 224 4.4E-9 T 12-10-2018 NPD12_3418 5387dc73d5a3e7a6d308a56704b049f1 407 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 43 399 7.1E-79 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_2078 8b1769bc24cb3670cfdb44eda357302b 576 Gene3D G3DSA:2.30.310.10 1 167 5.6E-60 T 12-10-2018 NPD12_2078 8b1769bc24cb3670cfdb44eda357302b 576 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 453 3.4E-152 T 12-10-2018 NPD12_2078 8b1769bc24cb3670cfdb44eda357302b 576 Pfam PF05670 Domain of unknown function (DUF814) 460 547 2.5E-31 T 12-10-2018 IPR008532 Domain of unknown function DUF814 NPD12_2652 0e3d4a327bae3be0bfd6430c79c466ab 311 Gene3D G3DSA:1.20.58.340 235 311 1.3E-26 T 12-10-2018 NPD12_2652 0e3d4a327bae3be0bfd6430c79c466ab 311 Pfam PF01544 CorA-like Mg2+ transporter protein 21 307 6.9E-68 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 NPD12_2652 0e3d4a327bae3be0bfd6430c79c466ab 311 SUPERFAMILY SSF143865 20 245 1.96E-36 T 12-10-2018 NPD12_2652 0e3d4a327bae3be0bfd6430c79c466ab 311 Gene3D G3DSA:1.20.58.340 122 233 3.0E-15 T 12-10-2018 NPD12_2652 0e3d4a327bae3be0bfd6430c79c466ab 311 SUPERFAMILY SSF144083 246 309 1.31E-19 T 12-10-2018 NPD12_2652 0e3d4a327bae3be0bfd6430c79c466ab 311 Gene3D G3DSA:3.30.460.20 9 121 1.3E-12 T 12-10-2018 NPD12_3429 48223c922389f576746bb2c8ac135a40 214 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 12 213 6.2E-48 T 12-10-2018 IPR010178 Integral membrane protein 1906 NPD12_3429 48223c922389f576746bb2c8ac135a40 214 Pfam PF07314 Protein of unknown function (DUF1461) 12 186 8.8E-46 T 12-10-2018 IPR010178 Integral membrane protein 1906 NPD12_3167 af62b2275a07363e1fe831791e2eb360 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.308 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 NPD12_3167 af62b2275a07363e1fe831791e2eb360 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 146 3.2E-55 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 NPD12_3167 af62b2275a07363e1fe831791e2eb360 149 Gene3D G3DSA:3.50.80.10 1 148 5.1E-59 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily NPD12_3167 af62b2275a07363e1fe831791e2eb360 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 8.5E-56 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 NPD12_3167 af62b2275a07363e1fe831791e2eb360 149 SUPERFAMILY SSF69500 1 145 1.44E-55 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily NPD12_363 9a43197e3706915847bb2d37c275a989 304 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 NPD12_363 9a43197e3706915847bb2d37c275a989 304 Gene3D G3DSA:3.40.50.1100 5 298 2.4E-123 T 12-10-2018 NPD12_363 9a43197e3706915847bb2d37c275a989 304 SUPERFAMILY SSF53686 2 302 1.57E-105 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme NPD12_363 9a43197e3706915847bb2d37c275a989 304 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 302 4.6E-133 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 NPD12_363 9a43197e3706915847bb2d37c275a989 304 Gene3D G3DSA:3.40.50.1100 44 143 2.4E-123 T 12-10-2018 NPD12_363 9a43197e3706915847bb2d37c275a989 304 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 34 47 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 NPD12_363 9a43197e3706915847bb2d37c275a989 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 290 3.9E-72 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme NPD12_363 9a43197e3706915847bb2d37c275a989 304 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 302 1.7E-130 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 NPD12_2627 782b529e9bf3d0dfce8aeb4d5e57cb98 449 PIRSF PIRSF006603 5 448 6.7E-79 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2627 782b529e9bf3d0dfce8aeb4d5e57cb98 449 Pfam PF01554 MatE 262 408 4.1E-17 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2627 782b529e9bf3d0dfce8aeb4d5e57cb98 449 Pfam PF01554 MatE 30 190 1.6E-19 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2627 782b529e9bf3d0dfce8aeb4d5e57cb98 449 TIGRFAM TIGR00797 matE: MATE efflux family protein 31 418 4.7E-53 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SMART SM00471 561 696 5.2E-8 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SUPERFAMILY SSF55785 130 233 1.13E-11 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Pfam PF13487 HD domain 617 678 1.4E-22 T 12-10-2018 NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SMART SM00267 384 553 1.9E-40 T 12-10-2018 IPR000160 GGDEF domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Gene3D G3DSA:3.30.450.20 254 381 2.1E-20 T 12-10-2018 NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SMART SM00091 267 332 0.0055 T 12-10-2018 IPR000014 PAS domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SMART SM00091 141 215 3.3 T 12-10-2018 IPR000014 PAS domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SUPERFAMILY SSF109604 566 724 4.59E-36 T 12-10-2018 NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Gene3D G3DSA:1.10.3210.10 543 730 7.5E-68 T 12-10-2018 NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Gene3D G3DSA:3.30.450.20 122 253 2.0E-15 T 12-10-2018 NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 391 540 4.0E-36 T 12-10-2018 IPR000160 GGDEF domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Pfam PF13426 PAS domain 278 383 1.0E-10 T 12-10-2018 IPR000014 PAS domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Pfam PF13426 PAS domain 171 254 9.0E-4 T 12-10-2018 IPR000014 PAS domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Gene3D G3DSA:3.30.70.270 382 542 7.4E-41 T 12-10-2018 NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 264 391 5.0E-14 T 12-10-2018 IPR000014 PAS domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 262 2.2E-9 T 12-10-2018 IPR000014 PAS domain NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SUPERFAMILY SSF55785 252 381 4.71E-18 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 SUPERFAMILY SSF55073 400 539 6.83E-33 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_1766 25a1cc01fc4ec17b64bfd8d011ad338b 732 Pfam PF00990 Diguanylate cyclase, GGDEF domain 395 539 2.2E-34 T 12-10-2018 IPR000160 GGDEF domain NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 Gene3D G3DSA:1.10.220.30 1 86 6.3E-20 T 12-10-2018 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 3.4E-74 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 3.4E-74 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 36 62 3.4E-74 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 3.4E-74 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 3.4E-74 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 117 140 3.4E-74 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 7 23 3.4E-74 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 Gene3D G3DSA:1.10.220.30 105 197 4.9E-32 T 12-10-2018 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 SUPERFAMILY SSF48029 117 328 3.01E-66 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 Pfam PF01706 FliG C-terminal domain 220 327 9.2E-41 T 12-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 Pfam PF14841 FliG middle domain 118 191 7.7E-30 T 12-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 337 1.5E-128 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 Pfam PF14842 FliG N-terminal domain 6 109 2.7E-32 T 12-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 PIRSF PIRSF003161 1 337 7.0E-117 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 Gene3D G3DSA:1.10.220.30 198 337 7.9E-47 T 12-10-2018 NPD12_2711 9f5eb2eb827f34997cc760880e2a7dd8 337 SUPERFAMILY SSF48029 8 107 1.96E-20 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 15 308 2.1E-118 T 12-10-2018 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 ProSitePatterns PS01087 Radical activating enzymes signature. 26 47 - T 12-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 Gene3D G3DSA:3.20.20.70 11 72 3.2E-14 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 Gene3D G3DSA:3.20.20.70 93 314 3.0E-66 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 TIGRFAM TIGR04395 cutC_activ_rSAM: choline TMA-lyase-activating enzyme 9 317 1.2E-172 T 12-10-2018 IPR030905 Choline TMA-lyase-activating enzyme NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 PIRSF PIRSF000371 6 315 1.7E-99 T 12-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 Pfam PF13353 4Fe-4S single cluster domain 25 63 1.4E-5 T 12-10-2018 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 Hamap MF_02059 Choline trimethylamine-lyase activating enzyme [cutD]. 8 317 62.207 T 12-10-2018 IPR030905 Choline TMA-lyase-activating enzyme NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 SUPERFAMILY SSF102114 95 287 2.16E-19 T 12-10-2018 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 Pfam PF04055 Radical SAM superfamily 33 253 3.3E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 Pfam PF13187 4Fe-4S dicluster domain 64 111 1.1E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2251 3b3b74190020140e5e7c1ea0ea8039a8 317 SUPERFAMILY SSF54862 14 158 1.85E-24 T 12-10-2018 NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 Pfam PF13361 UvrD-like helicase C-terminal domain 276 612 3.1E-73 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 Gene3D G3DSA:1.10.486.10 382 545 1.3E-123 T 12-10-2018 NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 SUPERFAMILY SSF52540 4 639 1.77E-178 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 Gene3D G3DSA:3.40.50.300 7 273 1.2E-103 T 12-10-2018 NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 Gene3D G3DSA:3.40.50.300 279 630 1.3E-123 T 12-10-2018 NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 4 736 5.6E-288 T 12-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 271 9.3E-81 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 NPD12_3400 bd44702242307914c8ee2c67e5edc9e6 738 Gene3D G3DSA:1.10.10.160 111 186 1.2E-103 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily NPD12_881 7f5ffa712189489a50631275348483df 232 Gene3D G3DSA:1.10.10.10 131 229 7.7E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_881 7f5ffa712189489a50631275348483df 232 Gene3D G3DSA:3.40.50.2300 2 130 5.0E-33 T 12-10-2018 NPD12_881 7f5ffa712189489a50631275348483df 232 SUPERFAMILY SSF52172 3 118 3.84E-34 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_881 7f5ffa712189489a50631275348483df 232 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_881 7f5ffa712189489a50631275348483df 232 SMART SM00862 147 224 1.9E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_881 7f5ffa712189489a50631275348483df 232 SUPERFAMILY SSF46894 123 224 2.44E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_881 7f5ffa712189489a50631275348483df 232 SMART SM00448 2 112 2.4E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_881 7f5ffa712189489a50631275348483df 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 1.6E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 Pfam PF02743 Cache domain 35 268 7.8E-26 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 Gene3D G3DSA:3.30.450.20 142 289 1.4E-24 T 12-10-2018 NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 464 607 6.5E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 SUPERFAMILY SSF103190 94 161 1.28E-5 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 SMART SM00283 394 669 4.1E-61 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 SMART SM00304 307 365 0.0013 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 Gene3D G3DSA:1.10.287.950 353 669 3.3E-65 T 12-10-2018 NPD12_869 93618b0bf7ab8129a5355cf8b7bf1fb4 670 SUPERFAMILY SSF58104 340 669 9.59E-69 T 12-10-2018 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Gene3D G3DSA:3.40.120.10 32 188 1.6E-45 T 12-10-2018 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 451 5.0E-25 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 SUPERFAMILY SSF53738 29 236 4.32E-42 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 SUPERFAMILY SSF53738 212 315 4.32E-17 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 222 312 2.0E-19 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Gene3D G3DSA:3.40.120.10 324 452 2.4E-40 T 12-10-2018 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Gene3D G3DSA:3.30.310.50 484 572 1.0E-6 T 12-10-2018 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 SUPERFAMILY SSF55957 444 573 8.24E-14 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Gene3D G3DSA:3.40.120.10 205 323 3.0E-21 T 12-10-2018 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 SUPERFAMILY SSF53738 304 455 2.28E-33 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 501 558 1.0E-8 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3224 a3e94eb7ad65d4242273871086043c9f 575 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 179 1.1E-38 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 SUPERFAMILY SSF52540 43 353 3.64E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 Gene3D G3DSA:1.20.120.140 6 306 2.6E-130 T 12-10-2018 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 Gene3D G3DSA:3.40.50.300 91 285 2.6E-130 T 12-10-2018 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 SMART SM00962 101 296 2.0E-118 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 448 34.859 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 Pfam PF00448 SRP54-type protein, GTPase domain 102 296 2.0E-78 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 431 3.3E-189 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 SMART SM00963 2 87 1.8E-34 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 SUPERFAMILY SSF47446 327 430 1.41E-35 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 Gene3D G3DSA:1.10.260.30 327 446 8.4E-41 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 PRINTS PR00364 Disease resistance protein signature 265 279 4.8E-5 T 12-10-2018 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 PRINTS PR00364 Disease resistance protein signature 356 372 4.8E-5 T 12-10-2018 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 PRINTS PR00364 Disease resistance protein signature 103 118 4.8E-5 T 12-10-2018 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 Pfam PF02978 Signal peptide binding domain 327 429 6.3E-34 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 7.6E-23 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 SMART SM00382 100 247 2.9E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2497 0f7b24ba25a8bcb2013631af27a6bbad 449 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_3208 4480233b6c8c7c7099a9cb488fd4b454 408 Pfam PF13439 Glycosyltransferase Family 4 19 205 6.5E-13 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_3208 4480233b6c8c7c7099a9cb488fd4b454 408 Pfam PF00534 Glycosyl transferases group 1 217 382 4.3E-18 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_3208 4480233b6c8c7c7099a9cb488fd4b454 408 SUPERFAMILY SSF53756 2 402 6.28E-54 T 12-10-2018 NPD12_3208 4480233b6c8c7c7099a9cb488fd4b454 408 Gene3D G3DSA:3.40.50.2000 229 394 7.9E-27 T 12-10-2018 NPD12_3208 4480233b6c8c7c7099a9cb488fd4b454 408 Gene3D G3DSA:3.40.50.2000 1 228 7.1E-22 T 12-10-2018 NPD12_2014 0104e393d4b542e0d6846d05dabb65e6 352 Gene3D G3DSA:3.60.10.10 50 352 1.3E-33 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily NPD12_2014 0104e393d4b542e0d6846d05dabb65e6 352 SUPERFAMILY SSF56219 52 352 9.68E-32 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily NPD12_1869 25f441a3e0591317de2f77b80b1ebbbe 327 Pfam PF00676 Dehydrogenase E1 component 16 311 4.4E-100 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 NPD12_1869 25f441a3e0591317de2f77b80b1ebbbe 327 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 8 320 4.8E-121 T 12-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 NPD12_1869 25f441a3e0591317de2f77b80b1ebbbe 327 SUPERFAMILY SSF52518 7 324 1.22E-109 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_1869 25f441a3e0591317de2f77b80b1ebbbe 327 Gene3D G3DSA:3.40.50.970 1 327 7.4E-136 T 12-10-2018 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Gene3D G3DSA:1.10.1780.10 1 150 7.8E-48 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 66 7.8E-15 T 12-10-2018 IPR004176 Clp, N-terminal NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 141 4.5E-15 T 12-10-2018 IPR004176 Clp, N-terminal NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 SMART SM00382 202 346 4.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 SMART SM00382 539 685 1.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Gene3D G3DSA:3.40.50.300 152 345 2.9E-74 T 12-10-2018 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Gene3D G3DSA:3.40.50.300 491 718 1.1E-90 T 12-10-2018 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Gene3D G3DSA:4.10.860.10 411 469 3.0E-48 T 12-10-2018 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Pfam PF02151 UvrB/uvrC motif 419 453 7.3E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Gene3D G3DSA:1.10.8.60 719 810 3.4E-29 T 12-10-2018 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 SUPERFAMILY SSF52540 488 808 3.24E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Pfam PF07724 AAA domain (Cdc48 subfamily) 538 713 3.8E-59 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Gene3D G3DSA:1.10.8.60 348 483 3.0E-48 T 12-10-2018 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 319 3.1E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 SMART SM01086 719 808 1.5E-35 T 12-10-2018 IPR019489 Clp ATPase, C-terminal NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 SUPERFAMILY SSF52540 162 473 3.11E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 SUPERFAMILY SSF81923 5 148 4.81E-28 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 664 4.2E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 543 561 4.2E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 588 606 4.2E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 617 635 4.2E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 799 1.3E-27 T 12-10-2018 IPR019489 Clp ATPase, C-terminal NPD12_3672 50f3d02af5d7679f1f6b2ac4739a12a0 811 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 573 591 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 NPD12_3436 0396880ca3364feda44b8ec39dad838a 254 Gene3D G3DSA:2.40.50.1020 142 253 5.9E-16 T 12-10-2018 NPD12_3436 0396880ca3364feda44b8ec39dad838a 254 Pfam PF04397 LytTr DNA-binding domain 158 252 5.2E-29 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_3436 0396880ca3364feda44b8ec39dad838a 254 Pfam PF00072 Response regulator receiver domain 7 111 3.1E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_3436 0396880ca3364feda44b8ec39dad838a 254 SMART SM00850 157 253 3.5E-37 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_3436 0396880ca3364feda44b8ec39dad838a 254 Gene3D G3DSA:3.40.50.2300 1 131 5.6E-30 T 12-10-2018 NPD12_3436 0396880ca3364feda44b8ec39dad838a 254 SUPERFAMILY SSF52172 4 122 3.27E-26 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_3436 0396880ca3364feda44b8ec39dad838a 254 SMART SM00448 4 115 7.4E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_351 a39b4374f487581e9d738584d67bf6bb 308 SUPERFAMILY SSF51569 1 304 5.57E-104 T 12-10-2018 NPD12_351 a39b4374f487581e9d738584d67bf6bb 308 PIRSF PIRSF001359 1 307 7.1E-100 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 NPD12_351 a39b4374f487581e9d738584d67bf6bb 308 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 305 4.2E-101 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 NPD12_351 a39b4374f487581e9d738584d67bf6bb 308 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 305 7.0E-107 T 12-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 NPD12_351 a39b4374f487581e9d738584d67bf6bb 308 Gene3D G3DSA:3.20.20.70 1 308 3.4E-123 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_351 a39b4374f487581e9d738584d67bf6bb 308 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 300 3.5E-88 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 Gene3D G3DSA:3.40.50.720 104 302 2.3E-117 T 12-10-2018 NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 Gene3D G3DSA:3.40.50.720 3 322 2.3E-117 T 12-10-2018 NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 302 1.3E-55 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 334 8.0E-26 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 SUPERFAMILY SSF52283 2 137 8.13E-34 T 12-10-2018 NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 177 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 199 221 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site NPD12_3411 23bbcb88de1bd650083704ba041eab4b 334 SUPERFAMILY SSF51735 104 303 5.18E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_415 47e31afdb1c02b28bbfd003bc72cf37c 125 Gene3D G3DSA:3.40.140.10 2 125 3.3E-31 T 12-10-2018 NPD12_415 47e31afdb1c02b28bbfd003bc72cf37c 125 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 94 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 NPD12_415 47e31afdb1c02b28bbfd003bc72cf37c 125 SUPERFAMILY SSF53927 1 122 1.57E-26 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_415 47e31afdb1c02b28bbfd003bc72cf37c 125 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 100 2.1E-6 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain NPD12_3292 8ea6a551d86cb109f827c4e99f4f4602 92 SUPERFAMILY SSF51182 1 91 2.33E-31 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_3292 8ea6a551d86cb109f827c4e99f4f4602 92 Pfam PF06865 Protein of unknown function (DUF1255) 2 91 2.9E-32 T 12-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 NPD12_3292 8ea6a551d86cb109f827c4e99f4f4602 92 Gene3D G3DSA:2.60.120.10 1 92 7.8E-31 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_961 a98e547eeb1cdc6bc2feba20dfd79e50 230 SUPERFAMILY SSF52172 4 186 1.96E-40 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_961 a98e547eeb1cdc6bc2feba20dfd79e50 230 Pfam PF00072 Response regulator receiver domain 7 115 7.4E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_961 a98e547eeb1cdc6bc2feba20dfd79e50 230 Gene3D G3DSA:3.40.50.2300 1 132 6.9E-37 T 12-10-2018 NPD12_961 a98e547eeb1cdc6bc2feba20dfd79e50 230 SMART SM00448 5 115 1.3E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_961 a98e547eeb1cdc6bc2feba20dfd79e50 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 1.2E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_961 a98e547eeb1cdc6bc2feba20dfd79e50 230 SMART SM00862 152 228 2.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_961 a98e547eeb1cdc6bc2feba20dfd79e50 230 Gene3D G3DSA:1.10.10.10 133 230 5.7E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_567 d97951c26e0fbee8a5a05458f0e8c3ee 149 SUPERFAMILY SSF53098 1 145 6.7E-53 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_567 d97951c26e0fbee8a5a05458f0e8c3ee 149 Pfam PF00075 RNase H 2 144 1.3E-44 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 NPD12_567 d97951c26e0fbee8a5a05458f0e8c3ee 149 Gene3D G3DSA:3.30.420.10 1 148 1.3E-54 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_567 d97951c26e0fbee8a5a05458f0e8c3ee 149 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 25.255 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 NPD12_596 c3da506be234102609eec0580ac5b645 1150 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1145 0.0 T 12-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 NPD12_596 c3da506be234102609eec0580ac5b645 1150 Gene3D G3DSA:3.40.50.300 276 393 4.0E-27 T 12-10-2018 NPD12_596 c3da506be234102609eec0580ac5b645 1150 Gene3D G3DSA:3.40.50.300 519 685 8.9E-43 T 12-10-2018 NPD12_596 c3da506be234102609eec0580ac5b645 1150 Pfam PF12705 PD-(D/E)XK nuclease superfamily 775 1116 2.0E-57 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type NPD12_596 c3da506be234102609eec0580ac5b645 1150 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1147 66.717 T 12-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 NPD12_596 c3da506be234102609eec0580ac5b645 1150 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 333 682 1.4E-16 T 12-10-2018 NPD12_596 c3da506be234102609eec0580ac5b645 1150 Gene3D G3DSA:3.40.50.300 1 110 1.8E-26 T 12-10-2018 NPD12_596 c3da506be234102609eec0580ac5b645 1150 Gene3D G3DSA:3.40.50.300 111 269 3.3E-23 T 12-10-2018 NPD12_596 c3da506be234102609eec0580ac5b645 1150 SUPERFAMILY SSF52540 289 735 1.81E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 Gene3D G3DSA:3.40.50.150 44 387 3.4E-43 T 12-10-2018 NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 Pfam PF12950 TaqI-like C-terminal specificity domain 395 543 1.3E-13 T 12-10-2018 IPR025931 TaqI-like C-terminal specificity domain NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 Pfam PF07669 Eco57I restriction-modification methylase 182 291 1.0E-7 T 12-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 88 102 1.7E-12 T 12-10-2018 NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 182 194 1.7E-12 T 12-10-2018 NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 58 74 1.7E-12 T 12-10-2018 NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 218 242 1.7E-12 T 12-10-2018 NPD12_3199 ae737f7b5987612a2f141de5e0d25efd 577 SUPERFAMILY SSF53335 6 318 8.59E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3032 017ed94c679cfd227cb1ca204a20009f 207 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 4 139 7.5E-17 T 12-10-2018 IPR018755 Bacteriophage Mu-like, Gp48 NPD12_2932 8bb9d2a5c81ce934497a9221659c22d8 159 Pfam PF00731 AIR carboxylase 2 147 1.0E-61 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 NPD12_2932 8bb9d2a5c81ce934497a9221659c22d8 159 SUPERFAMILY SSF52255 1 156 9.42E-60 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 NPD12_2932 8bb9d2a5c81ce934497a9221659c22d8 159 PIRSF PIRSF001338 1 158 3.4E-64 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 NPD12_2932 8bb9d2a5c81ce934497a9221659c22d8 159 Gene3D G3DSA:3.40.50.7700 1 158 1.3E-63 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 NPD12_2932 8bb9d2a5c81ce934497a9221659c22d8 159 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 155 2.8E-58 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 NPD12_2932 8bb9d2a5c81ce934497a9221659c22d8 159 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 153 30.643 T 12-10-2018 IPR033747 Class I PurE NPD12_2932 8bb9d2a5c81ce934497a9221659c22d8 159 SMART SM01001 1 149 1.2E-84 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 Pfam PF02154 Flagellar motor switch protein FliM 39 229 3.4E-61 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 Gene3D G3DSA:3.40.1550.10 45 230 3.1E-59 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 PIRSF PIRSF002888 1 331 4.7E-116 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 SUPERFAMILY SSF103039 45 229 2.88E-28 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 2.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 2.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 2.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 2.4E-24 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 SUPERFAMILY SSF101801 252 326 2.09E-15 T 12-10-2018 IPR036429 SpoA-like superfamily NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 323 3.2E-18 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 Gene3D G3DSA:2.30.330.10 239 329 5.8E-11 T 12-10-2018 IPR036429 SpoA-like superfamily NPD12_2777 446530cc95158a4aa75b8d71992fb3e9 331 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 323 1.9E-100 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 NPD12_3601 febcab0422c0e8ad1d6da97d45ac66ad 234 Gene3D G3DSA:3.40.630.40 28 234 1.8E-57 T 12-10-2018 NPD12_3601 febcab0422c0e8ad1d6da97d45ac66ad 234 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 38 229 3.9E-85 T 12-10-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 NPD12_3601 febcab0422c0e8ad1d6da97d45ac66ad 234 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 40 226 4.7E-50 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3601 febcab0422c0e8ad1d6da97d45ac66ad 234 SMART SM00646 119 227 2.0E-19 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3601 febcab0422c0e8ad1d6da97d45ac66ad 234 SUPERFAMILY SSF53187 38 231 1.07E-49 T 12-10-2018 NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 SUPERFAMILY SSF54211 79 158 1.69E-25 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 162 9.0E-63 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 Gene3D G3DSA:3.30.230.10 73 165 1.4E-33 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 SUPERFAMILY SSF54768 7 74 1.67E-23 T 12-10-2018 NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 73 1.5E-30 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 Gene3D G3DSA:3.30.160.20 1 72 1.5E-31 T 12-10-2018 NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 33.14 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 NPD12_3622 0410bc51f8b24844f239e1962a7c9fa9 165 Pfam PF03719 Ribosomal protein S5, C-terminal domain 86 156 2.7E-30 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 NPD12_2854 da290f946e3c30da497d0f1611d9653d 173 Gene3D G3DSA:3.90.1140.10 1 173 7.9E-34 T 12-10-2018 NPD12_2854 da290f946e3c30da497d0f1611d9653d 173 SUPERFAMILY SSF55144 1 173 2.79E-30 T 12-10-2018 IPR009097 Cyclic phosphodiesterase NPD12_2854 da290f946e3c30da497d0f1611d9653d 173 Pfam PF13563 2'-5' RNA ligase superfamily 31 154 1.6E-8 T 12-10-2018 NPD12_2854 da290f946e3c30da497d0f1611d9653d 173 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 173 20.823 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 NPD12_2854 da290f946e3c30da497d0f1611d9653d 173 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 171 2.2E-34 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 NPD12_1748 12d988c94f39f4ba1e828fade37c7a88 272 Pfam PF03180 NLPA lipoprotein 43 271 3.6E-51 T 12-10-2018 IPR004872 Lipoprotein NlpA family NPD12_1748 12d988c94f39f4ba1e828fade37c7a88 272 SUPERFAMILY SSF53850 43 272 2.17E-47 T 12-10-2018 NPD12_1748 12d988c94f39f4ba1e828fade37c7a88 272 Gene3D G3DSA:3.40.190.10 126 229 1.2E-61 T 12-10-2018 NPD12_1748 12d988c94f39f4ba1e828fade37c7a88 272 Gene3D G3DSA:3.40.190.10 47 270 1.2E-61 T 12-10-2018 NPD12_2850 279d2e7309ae5f734187b548f511ff2c 182 SUPERFAMILY SSF53271 6 170 1.84E-44 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_2850 279d2e7309ae5f734187b548f511ff2c 182 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 37.825 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 NPD12_2850 279d2e7309ae5f734187b548f511ff2c 182 Gene3D G3DSA:3.40.50.2020 2 179 1.8E-61 T 12-10-2018 NPD12_2850 279d2e7309ae5f734187b548f511ff2c 182 Pfam PF00156 Phosphoribosyl transferase domain 12 146 1.3E-24 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Pfam PF08239 Bacterial SH3 domain 194 244 9.6E-15 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Pfam PF08239 Bacterial SH3 domain 434 485 2.3E-15 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Pfam PF08239 Bacterial SH3 domain 356 406 8.2E-14 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Pfam PF08239 Bacterial SH3 domain 276 327 4.5E-15 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Pfam PF02389 Cornifin (SPRR) family 538 627 5.7E-7 T 12-10-2018 NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Pfam PF00877 NlpC/P60 family 677 764 6.3E-28 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 SUPERFAMILY SSF54001 36 163 2.55E-18 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Gene3D G3DSA:2.30.30.40 335 406 1.1E-17 T 12-10-2018 NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Gene3D G3DSA:2.30.30.40 269 326 4.7E-19 T 12-10-2018 NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Gene3D G3DSA:2.30.30.40 186 244 1.2E-16 T 12-10-2018 NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Gene3D G3DSA:2.30.30.40 425 496 1.7E-18 T 12-10-2018 NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 SUPERFAMILY SSF54001 662 765 1.71E-42 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Pfam PF05257 CHAP domain 53 137 4.3E-13 T 12-10-2018 IPR007921 CHAP domain NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 SMART SM00287 267 330 7.6E-11 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 SMART SM00287 347 409 1.4E-9 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 SMART SM00287 186 248 7.3E-10 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 SMART SM00287 424 488 8.7E-10 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Gene3D G3DSA:3.90.1720.10 583 771 6.6E-58 T 12-10-2018 NPD12_671 8038e6654ddeb1e14f2d9a245a3f3736 774 Gene3D G3DSA:3.90.1720.10 46 163 8.7E-22 T 12-10-2018 NPD12_3182 4add6c8e5b044ff40037ce6885f07138 246 Gene3D G3DSA:3.30.70.980 134 204 1.3E-54 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 NPD12_3182 4add6c8e5b044ff40037ce6885f07138 246 Pfam PF01709 Transcriptional regulator 5 238 1.0E-97 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 NPD12_3182 4add6c8e5b044ff40037ce6885f07138 246 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 36.785 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 NPD12_3182 4add6c8e5b044ff40037ce6885f07138 246 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 239 1.2E-99 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 NPD12_3182 4add6c8e5b044ff40037ce6885f07138 246 Gene3D G3DSA:1.10.10.200 1 80 7.4E-32 T 12-10-2018 IPR017856 Integrase-like, N-terminal NPD12_3182 4add6c8e5b044ff40037ce6885f07138 246 SUPERFAMILY SSF75625 3 244 2.88E-96 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 NPD12_3182 4add6c8e5b044ff40037ce6885f07138 246 Gene3D G3DSA:3.30.70.980 85 237 1.3E-54 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 NPD12_1624 2971039778191072b7d09a12fe614f6b 264 Pfam PF00005 ABC transporter 23 179 1.5E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1624 2971039778191072b7d09a12fe614f6b 264 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1624 2971039778191072b7d09a12fe614f6b 264 SMART SM00382 30 229 2.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1624 2971039778191072b7d09a12fe614f6b 264 SUPERFAMILY SSF52540 14 251 5.68E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1624 2971039778191072b7d09a12fe614f6b 264 Gene3D G3DSA:3.40.50.300 1 261 1.6E-62 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Gene3D G3DSA:3.30.980.50 637 746 7.1E-42 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 SUPERFAMILY SSF89260 973 1086 4.84E-14 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Pfam PF00801 PKD domain 770 824 4.7E-14 T 12-10-2018 IPR000601 PKD domain NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Pfam PF01752 Collagenase 284 606 4.8E-86 T 12-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 SUPERFAMILY SSF49299 765 834 1.26E-19 T 12-10-2018 IPR035986 PKD domain superfamily NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Gene3D G3DSA:1.10.1740.190 353 496 2.6E-61 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Gene3D G3DSA:2.60.120.380 1093 1209 7.2E-29 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 1130 1195 1.7E-5 T 12-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 139 157 5.4E-27 T 12-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 443 459 5.4E-27 T 12-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 480 498 5.4E-27 T 12-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 426 440 5.4E-27 T 12-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 SMART SM00089 756 835 3.3E-18 T 12-10-2018 IPR022409 PKD/Chitinase domain NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Gene3D G3DSA:1.10.390.20 497 636 6.9E-59 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 SUPERFAMILY SSF89260 1096 1208 1.7E-33 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Pfam PF08453 Peptidase family M9 N-terminal 73 254 1.8E-51 T 12-10-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 SUPERFAMILY SSF89260 841 952 2.62E-16 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Gene3D G3DSA:2.60.120.380 971 1091 4.5E-17 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Gene3D G3DSA:2.60.120.380 838 959 3.6E-19 T 12-10-2018 NPD12_1860 dcb6d9861220444776c5bb8c433a91b8 1209 Gene3D G3DSA:2.60.40.10 747 833 1.1E-23 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_2520 2f1dd118bf584e7243aaeb91711535ee 481 Pfam PF13520 Amino acid permease 5 440 2.9E-56 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2520 2f1dd118bf584e7243aaeb91711535ee 481 PIRSF PIRSF006060 1 480 3.7E-53 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2520 2f1dd118bf584e7243aaeb91711535ee 481 Gene3D G3DSA:1.20.1740.10 1 464 4.1E-36 T 12-10-2018 NPD12_1636 2b2e230adf56b722cc141ae981ece5ff 157 Gene3D G3DSA:3.30.1490.190 90 152 5.9E-10 T 12-10-2018 NPD12_1636 2b2e230adf56b722cc141ae981ece5ff 157 SUPERFAMILY SSF46785 8 141 1.35E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1636 2b2e230adf56b722cc141ae981ece5ff 157 Pfam PF01475 Ferric uptake regulator family 14 129 1.0E-23 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 NPD12_1636 2b2e230adf56b722cc141ae981ece5ff 157 Gene3D G3DSA:1.10.10.10 1 83 1.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1870 38701b495d51d99df15de70b9143955d 323 Pfam PF02780 Transketolase, C-terminal domain 193 315 1.1E-41 T 12-10-2018 IPR033248 Transketolase, C-terminal domain NPD12_1870 38701b495d51d99df15de70b9143955d 323 SUPERFAMILY SSF52518 1 203 7.5E-70 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_1870 38701b495d51d99df15de70b9143955d 323 Gene3D G3DSA:3.40.50.970 1 192 4.0E-84 T 12-10-2018 NPD12_1870 38701b495d51d99df15de70b9143955d 323 SMART SM00861 4 179 3.2E-64 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain NPD12_1870 38701b495d51d99df15de70b9143955d 323 Gene3D G3DSA:3.40.50.920 193 323 4.6E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_1870 38701b495d51d99df15de70b9143955d 323 Pfam PF02779 Transketolase, pyrimidine binding domain 3 179 2.7E-50 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain NPD12_1870 38701b495d51d99df15de70b9143955d 323 SUPERFAMILY SSF52922 190 322 4.58E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_2425 4afea94573299b37a992c48af73d1b48 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 163 3.1E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_2425 4afea94573299b37a992c48af73d1b48 170 SUPERFAMILY SSF88659 97 166 1.2E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2425 4afea94573299b37a992c48af73d1b48 170 Gene3D G3DSA:1.10.10.10 92 168 5.0E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2425 4afea94573299b37a992c48af73d1b48 170 SUPERFAMILY SSF88946 6 88 2.51E-20 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2425 4afea94573299b37a992c48af73d1b48 170 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 34 64 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_2425 4afea94573299b37a992c48af73d1b48 170 Gene3D G3DSA:1.10.1740.10 4 91 1.0E-18 T 12-10-2018 NPD12_2425 4afea94573299b37a992c48af73d1b48 170 Pfam PF04542 Sigma-70 region 2 13 78 5.6E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 Gene3D G3DSA:1.10.10.10 3 87 1.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 Gene3D G3DSA:3.40.190.10 93 289 1.2E-33 T 12-10-2018 NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 SUPERFAMILY SSF46785 4 112 2.1E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 Gene3D G3DSA:3.40.190.10 166 267 1.2E-33 T 12-10-2018 NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 Pfam PF03466 LysR substrate binding domain 93 291 7.3E-28 T 12-10-2018 IPR005119 LysR, substrate-binding NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.8E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.8E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.8E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.3E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_821 c00cd42b96d9191c57a1021ba745dcfe 291 SUPERFAMILY SSF53850 92 291 1.19E-31 T 12-10-2018 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Gene3D G3DSA:3.40.1360.10 232 354 1.1E-38 T 12-10-2018 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 PIRSF PIRSF002811 1 586 5.0E-164 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Pfam PF13155 Toprim-like 252 336 6.1E-21 T 12-10-2018 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 TIGRFAM TIGR01391 dnaG: DNA primase 2 404 1.0E-139 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Gene3D G3DSA:3.90.580.10 1 100 1.1E-36 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 SUPERFAMILY SSF48024 443 499 6.8E-6 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Gene3D G3DSA:3.90.980.10 102 231 9.7E-43 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Hamap MF_00974 DNA primase [dnaG]. 1 581 27.626 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 SMART SM00400 33 87 2.7E-33 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Pfam PF08275 DNA primase catalytic core, N-terminal domain 122 241 2.0E-40 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal NPD12_2987 47a117b100626c4bd0b1397db7307868 590 SMART SM00493 249 320 3.5E-22 T 12-10-2018 IPR006171 TOPRIM domain NPD12_2987 47a117b100626c4bd0b1397db7307868 590 SUPERFAMILY SSF56731 109 411 1.83E-97 T 12-10-2018 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Pfam PF10410 DnaB-helicase binding domain of primase 356 408 1.5E-7 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 SUPERFAMILY SSF57783 2 96 8.67E-32 T 12-10-2018 NPD12_2987 47a117b100626c4bd0b1397db7307868 590 Pfam PF01807 CHC2 zinc finger 3 98 3.1E-36 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 NPD12_2983 fa6ccb55e3acfb9973d348e652d423e2 267 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 246 3.9E-81 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 NPD12_2983 fa6ccb55e3acfb9973d348e652d423e2 267 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 243 4.8E-63 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 NPD12_2983 fa6ccb55e3acfb9973d348e652d423e2 267 Gene3D G3DSA:3.40.1390.30 10 235 9.5E-75 T 12-10-2018 NPD12_2983 fa6ccb55e3acfb9973d348e652d423e2 267 SUPERFAMILY SSF102705 5 266 2.49E-89 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily NPD12_2983 fa6ccb55e3acfb9973d348e652d423e2 267 Gene3D G3DSA:3.40.1390.30 102 225 9.5E-75 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.0E-18 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 7.0E-18 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 7.0E-18 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 248 262 7.0E-18 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.4E-25 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 4.4E-25 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 4.4E-25 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 4.4E-25 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 4.4E-25 T 12-10-2018 NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 SUPERFAMILY SSF51905 1 324 7.62E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 Gene3D G3DSA:3.50.50.60 121 255 3.9E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 Gene3D G3DSA:3.50.50.60 4 297 3.9E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1263 66a401b4896b7f95dd4a08312c4c564a 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 296 4.3E-36 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_3489 51bcfe2fb6d02df8f10d6fedf613bacb 292 SMART SM00382 26 208 9.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3489 51bcfe2fb6d02df8f10d6fedf613bacb 292 Pfam PF00005 ABC transporter 20 161 6.4E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3489 51bcfe2fb6d02df8f10d6fedf613bacb 292 SUPERFAMILY SSF52540 3 224 2.44E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3489 51bcfe2fb6d02df8f10d6fedf613bacb 292 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3489 51bcfe2fb6d02df8f10d6fedf613bacb 292 Gene3D G3DSA:3.40.50.300 1 239 5.8E-60 T 12-10-2018 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 Pfam PF13181 Tetratricopeptide repeat 214 235 0.0033 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 Pfam PF13181 Tetratricopeptide repeat 111 143 3.2E-7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 Pfam PF13181 Tetratricopeptide repeat 248 277 2.4E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 Gene3D G3DSA:1.25.40.10 4 180 1.4E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SMART SM00028 76 109 5.6E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SMART SM00028 42 75 4.6E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SMART SM00028 110 143 3.4E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SMART SM00028 212 245 1.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SMART SM00028 178 211 0.33 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SMART SM00028 144 177 46.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SMART SM00028 246 279 4.8E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 Pfam PF13432 Tetratricopeptide repeat 46 103 3.4E-8 T 12-10-2018 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 Pfam PF13431 Tetratricopeptide repeat 167 198 3.1E-5 T 12-10-2018 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 Gene3D G3DSA:1.25.40.10 181 300 4.6E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1330 69f7e0c77c4492a0cb36d7bd5d8b3b7b 303 SUPERFAMILY SSF48452 5 280 1.29E-38 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 Pfam PF00154 recA bacterial DNA recombination protein 11 272 2.5E-144 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 SUPERFAMILY SSF54752 272 329 6.54E-20 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 Gene3D G3DSA:3.40.50.300 30 271 1.6E-82 T 12-10-2018 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 Hamap MF_00268 Protein RecA [recA]. 9 333 51.92 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 ProSitePatterns PS00321 recA signature. 217 225 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 Gene3D G3DSA:3.30.250.10 272 347 1.6E-25 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 8 327 5.2E-173 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 SMART SM00382 61 232 2.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 SUPERFAMILY SSF52540 7 271 8.74E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 PRINTS PR00142 RecA protein signature 301 318 2.2E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 PRINTS PR00142 RecA protein signature 131 160 2.2E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 PRINTS PR00142 RecA protein signature 214 242 2.2E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 PRINTS PR00142 RecA protein signature 97 126 2.2E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 PRINTS PR00142 RecA protein signature 247 276 2.2E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_2452 928d8e66f0f9a79832d58071c3372c26 352 PRINTS PR00142 RecA protein signature 169 198 2.2E-84 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 NPD12_3581 9fc44192662d92df0a66a3d3633e8f2b 356 SUPERFAMILY SSF52518 3 239 1.23E-63 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_3581 9fc44192662d92df0a66a3d3633e8f2b 356 Gene3D G3DSA:3.40.50.920 236 353 9.6E-19 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_3581 9fc44192662d92df0a66a3d3633e8f2b 356 Gene3D G3DSA:3.40.50.970 1 189 2.4E-65 T 12-10-2018 NPD12_3581 9fc44192662d92df0a66a3d3633e8f2b 356 SUPERFAMILY SSF52922 247 354 1.57E-19 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 NPD12_3581 9fc44192662d92df0a66a3d3633e8f2b 356 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 250 344 9.5E-21 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II NPD12_3581 9fc44192662d92df0a66a3d3633e8f2b 356 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 237 5.1E-53 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 NPD12_2515 d4f8065f7e28773a3a7a244476a0ac89 372 Gene3D G3DSA:3.40.50.11540 89 237 2.6E-18 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2515 d4f8065f7e28773a3a7a244476a0ac89 372 Pfam PF13375 RnfC Barrel sandwich hybrid domain 3 62 7.8E-14 T 12-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain NPD12_2515 d4f8065f7e28773a3a7a244476a0ac89 372 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 85 227 3.2E-44 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2515 d4f8065f7e28773a3a7a244476a0ac89 372 TIGRFAM TIGR04481 PR_assoc_PrdC: proline reductase-associated electron transfer protein PrdC 6 371 7.4E-158 T 12-10-2018 IPR031001 Proline reductase-associated electron transfer protein PrdC NPD12_2515 d4f8065f7e28773a3a7a244476a0ac89 372 SUPERFAMILY SSF142019 42 245 9.55E-52 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_1324 1a33214954a2dc0488793b673b9587eb 208 Gene3D G3DSA:1.10.10.10 5 126 4.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1324 1a33214954a2dc0488793b673b9587eb 208 SUPERFAMILY SSF46785 6 82 4.44E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1324 1a33214954a2dc0488793b673b9587eb 208 SMART SM00345 12 71 1.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1324 1a33214954a2dc0488793b673b9587eb 208 Pfam PF02080 TrkA-C domain 135 203 2.8E-15 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 NPD12_1324 1a33214954a2dc0488793b673b9587eb 208 SUPERFAMILY SSF116726 134 203 5.36E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_1324 1a33214954a2dc0488793b673b9587eb 208 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 2.2E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1324 1a33214954a2dc0488793b673b9587eb 208 Gene3D G3DSA:3.30.70.1450 131 206 1.5E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_2459 c51a4a6a24652eb484eb59c16c2bd6b5 433 SUPERFAMILY SSF63411 3 205 3.33E-65 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_2459 c51a4a6a24652eb484eb59c16c2bd6b5 433 Gene3D G3DSA:3.30.830.10 2 215 1.3E-75 T 12-10-2018 NPD12_2459 c51a4a6a24652eb484eb59c16c2bd6b5 433 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 NPD12_2459 c51a4a6a24652eb484eb59c16c2bd6b5 433 Gene3D G3DSA:3.30.830.10 221 418 5.1E-45 T 12-10-2018 NPD12_2459 c51a4a6a24652eb484eb59c16c2bd6b5 433 SUPERFAMILY SSF63411 226 416 5.81E-39 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_2459 c51a4a6a24652eb484eb59c16c2bd6b5 433 Pfam PF05193 Peptidase M16 inactive domain 166 341 2.1E-38 T 12-10-2018 IPR007863 Peptidase M16, C-terminal NPD12_2459 c51a4a6a24652eb484eb59c16c2bd6b5 433 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 9.7E-42 T 12-10-2018 IPR011765 Peptidase M16, N-terminal NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 Pfam PF00005 ABC transporter 349 496 1.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 SUPERFAMILY SSF90123 4 314 3.27E-66 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 SUPERFAMILY SSF52540 323 568 2.05E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 Gene3D G3DSA:1.20.1560.10 1 314 1.8E-76 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 Gene3D G3DSA:3.40.50.300 317 571 7.5E-77 T 12-10-2018 NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 SMART SM00382 358 559 2.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 Pfam PF00664 ABC transporter transmembrane region 16 280 8.2E-38 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2121 4ea83b63e2cd5ecd67afffb58ead2663 576 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Gene3D G3DSA:3.10.20.600 284 357 8.9E-6 T 12-10-2018 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 366 377 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 405 416 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 128 273 1.2E-54 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 3 434 2.9E-173 T 12-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Pfam PF10531 SLBB domain 286 334 5.8E-15 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 104 2.0E-39 T 12-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Pfam PF13187 4Fe-4S dicluster domain 366 418 2.3E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 SUPERFAMILY SSF142019 87 293 1.57E-63 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 439 156.685 T 12-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 SUPERFAMILY SSF46548 324 435 1.57E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Gene3D G3DSA:1.10.1060.10 358 434 4.5E-10 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_532 2d3c5e51598b99997a309d042f10ee16 439 Gene3D G3DSA:3.40.50.11540 133 279 8.1E-13 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2037 dfe9be5b028a373eee08fe9551915856 105 Pfam PF00589 Phage integrase family 32 104 1.9E-11 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 NPD12_2037 dfe9be5b028a373eee08fe9551915856 105 Gene3D G3DSA:1.10.443.10 22 104 5.2E-14 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 NPD12_2037 dfe9be5b028a373eee08fe9551915856 105 SUPERFAMILY SSF56349 2 104 3.53E-16 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 NPD12_3068 a1f96f0e735700b063cb4e2801c36be3 381 Pfam PF10926 Protein of unknown function (DUF2800) 4 371 1.1E-150 T 12-10-2018 IPR021229 Protein of unknown function DUF2800 NPD12_873 0aad07f593795ba988d9f3cd33c7acff 446 SUPERFAMILY SSF53383 3 446 6.3E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_873 0aad07f593795ba988d9f3cd33c7acff 446 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 2 446 48.279 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 NPD12_873 0aad07f593795ba988d9f3cd33c7acff 446 Gene3D G3DSA:3.40.640.10 83 348 1.0E-166 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_873 0aad07f593795ba988d9f3cd33c7acff 446 Gene3D G3DSA:3.90.1150.10 72 442 1.0E-166 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_873 0aad07f593795ba988d9f3cd33c7acff 446 PIRSF PIRSF006815 2 446 1.3E-194 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 NPD12_873 0aad07f593795ba988d9f3cd33c7acff 446 Pfam PF02347 Glycine cleavage system P-protein 4 442 7.7E-142 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 Gene3D G3DSA:3.40.50.300 309 576 2.6E-64 T 12-10-2018 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 SUPERFAMILY SSF52540 11 291 1.78E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 Pfam PF02374 Anion-transporting ATPase 327 467 1.4E-31 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 Pfam PF02374 Anion-transporting ATPase 472 573 5.2E-6 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 Pfam PF02374 Anion-transporting ATPase 13 295 1.6E-78 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 Gene3D G3DSA:3.40.50.300 10 297 4.3E-79 T 12-10-2018 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 PIRSF PIRSF001327 2 581 1.0E-271 T 12-10-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 SUPERFAMILY SSF52540 312 545 1.09E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 17 296 8.2E-78 T 12-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 TIGRFAM TIGR04291 arsen_driv_ArsA: arsenical pump-driving ATPase 12 569 4.2E-259 T 12-10-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 SMART SM00382 12 234 3.9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_939 3c776e93aa252dc97f2e38818d2db8cb 581 SMART SM00382 325 519 0.32 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3109 2d8d6db84e46d5d5b3d06c7c37e90135 228 Gene3D G3DSA:1.10.150.20 49 91 9.1E-7 T 12-10-2018 NPD12_3109 2d8d6db84e46d5d5b3d06c7c37e90135 228 Pfam PF04002 RadC-like JAB domain 107 226 1.2E-44 T 12-10-2018 IPR025657 RadC-like JAB domain NPD12_3109 2d8d6db84e46d5d5b3d06c7c37e90135 228 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 177 182 - T 12-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site NPD12_3109 2d8d6db84e46d5d5b3d06c7c37e90135 228 Gene3D G3DSA:3.40.140.10 103 228 1.3E-45 T 12-10-2018 NPD12_3109 2d8d6db84e46d5d5b3d06c7c37e90135 228 SUPERFAMILY SSF47781 20 92 6.23E-8 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_3109 2d8d6db84e46d5d5b3d06c7c37e90135 228 TIGRFAM TIGR00608 radc: DNA repair protein RadC 15 228 3.0E-74 T 12-10-2018 IPR001405 Uncharacterised protein family UPF0758 NPD12_3109 2d8d6db84e46d5d5b3d06c7c37e90135 228 SUPERFAMILY SSF102712 160 196 6.15E-5 T 12-10-2018 NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 SUPERFAMILY SSF52172 2 126 1.42E-33 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 SMART SM00448 3 113 1.2E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 SMART SM00862 150 221 3.4E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 Gene3D G3DSA:3.40.50.2300 3 126 4.4E-32 T 12-10-2018 NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 221 3.0E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 Pfam PF00072 Response regulator receiver domain 5 111 3.1E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 Gene3D G3DSA:1.10.10.10 127 223 5.9E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_461 bcd88701bcbd6930c5b06bf7c4afe182 224 SUPERFAMILY SSF46894 131 222 1.25E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_617 da480821cee7207049e107c31e111ccb 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 7 200 1.5E-69 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_617 da480821cee7207049e107c31e111ccb 205 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 4 205 27.489 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_617 da480821cee7207049e107c31e111ccb 205 SUPERFAMILY SSF51391 5 201 1.14E-64 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_617 da480821cee7207049e107c31e111ccb 205 Pfam PF02581 Thiamine monophosphate synthase 7 188 7.9E-67 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_617 da480821cee7207049e107c31e111ccb 205 Gene3D G3DSA:3.20.20.70 1 203 1.8E-72 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1987 b81628c67ad4421efa1aa762758564ff 171 Gene3D G3DSA:3.10.120.10 91 168 5.3E-11 T 12-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily NPD12_1987 b81628c67ad4421efa1aa762758564ff 171 SMART SM01117 99 171 1.3E-11 T 12-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain NPD12_1987 b81628c67ad4421efa1aa762758564ff 171 SUPERFAMILY SSF55856 93 160 3.93E-14 T 12-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily NPD12_1987 b81628c67ad4421efa1aa762758564ff 171 Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain 100 170 9.3E-11 T 12-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 SMART SM00448 4 114 8.6E-46 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 Gene3D G3DSA:3.40.50.2300 1 132 1.0E-39 T 12-10-2018 NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 8.0E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 SUPERFAMILY SSF46894 129 230 2.27E-31 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 SUPERFAMILY SSF52172 4 126 9.25E-43 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 SMART SM00862 154 230 9.1E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 Gene3D G3DSA:1.10.10.10 133 232 1.4E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_529 8568340c01d4e12d6757ee9541634b4a 232 Pfam PF00072 Response regulator receiver domain 6 114 1.1E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_713 44cbec1d76c07799aff0ee9fe5fcffd9 146 Pfam PF01957 NfeD-like C-terminal, partner-binding 9 143 2.1E-19 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain NPD12_713 44cbec1d76c07799aff0ee9fe5fcffd9 146 SUPERFAMILY SSF141322 86 144 5.23E-8 T 12-10-2018 NPD12_713 44cbec1d76c07799aff0ee9fe5fcffd9 146 Gene3D G3DSA:2.40.50.140 71 146 5.4E-11 T 12-10-2018 NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 Gene3D G3DSA:3.30.230.10 1 156 1.0E-56 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 SUPERFAMILY SSF55060 159 279 3.17E-27 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 Pfam PF00288 GHMP kinases N terminal domain 83 141 1.7E-5 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 PIRSF PIRSF010376 1 280 9.7E-92 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 Pfam PF08544 GHMP kinases C terminal 195 272 3.0E-10 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 1 277 33.878 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 SUPERFAMILY SSF54211 3 155 1.9E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 273 3.2E-80 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 NPD12_275 d352620cecbd5fe3b354bef6df722a2b 280 Gene3D G3DSA:3.30.70.890 159 279 1.2E-26 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 SUPERFAMILY SSF55920 305 561 1.31E-51 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 SUPERFAMILY SSF53092 169 288 8.37E-5 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 Pfam PF16189 Creatinase/Prolidase N-terminal domain 149 308 1.7E-50 T 12-10-2018 NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 Gene3D G3DSA:3.40.350.10 1 147 1.8E-48 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 SUPERFAMILY SSF53092 10 132 7.85E-14 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 Pfam PF00557 Metallopeptidase family M24 310 526 1.3E-38 T 12-10-2018 IPR000994 Peptidase M24 NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 Gene3D G3DSA:3.90.230.10 302 596 6.8E-89 T 12-10-2018 NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 131 9.1E-17 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 Pfam PF16188 C-terminal region of peptidase_M24 536 596 3.1E-22 T 12-10-2018 IPR032416 Peptidase M24, C-terminal domain NPD12_2384 dcfde2a4ae05e5a6b6352a9d37f75753 597 Gene3D G3DSA:3.40.350.10 148 298 1.0E-45 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal NPD12_754 7d9fee4465b993a20bd23f5c561fd6bf 233 SMART SM00448 1 113 1.2E-6 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_754 7d9fee4465b993a20bd23f5c561fd6bf 233 SMART SM00850 133 224 9.0E-29 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_754 7d9fee4465b993a20bd23f5c561fd6bf 233 SUPERFAMILY SSF52172 26 140 1.85E-15 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_754 7d9fee4465b993a20bd23f5c561fd6bf 233 Gene3D G3DSA:3.40.50.2300 1 127 3.0E-17 T 12-10-2018 NPD12_754 7d9fee4465b993a20bd23f5c561fd6bf 233 Gene3D G3DSA:2.40.50.40 128 193 1.2E-18 T 12-10-2018 NPD12_754 7d9fee4465b993a20bd23f5c561fd6bf 233 Pfam PF04397 LytTr DNA-binding domain 134 223 7.6E-24 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_754 7d9fee4465b993a20bd23f5c561fd6bf 233 Pfam PF00072 Response regulator receiver domain 19 108 4.8E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2709 26613514298969987eeb24b383b9d0aa 436 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 8.0E-78 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2709 26613514298969987eeb24b383b9d0aa 436 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 7 434 1.8E-191 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2709 26613514298969987eeb24b383b9d0aa 436 Gene3D G3DSA:3.40.50.12240 16 436 1.1E-152 T 12-10-2018 NPD12_2709 26613514298969987eeb24b383b9d0aa 436 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 88 8.6E-7 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2709 26613514298969987eeb24b383b9d0aa 436 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 23 434 7.3E-213 T 12-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2709 26613514298969987eeb24b383b9d0aa 436 SUPERFAMILY SSF52540 93 359 1.19E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2709 26613514298969987eeb24b383b9d0aa 436 SMART SM00382 157 338 1.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_430 a10ca862a76cdb60329a491eed0ba74c 227 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 7 215 1.3E-57 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 NPD12_2671 411218c941e77da91008fb31ae8ee827 216 Pfam PF01813 ATP synthase subunit D 11 205 1.7E-62 T 12-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2671 411218c941e77da91008fb31ae8ee827 216 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 2 211 22.33 T 12-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2671 411218c941e77da91008fb31ae8ee827 216 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 4 210 1.9E-53 T 12-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Pfam PF08463 EcoEI R protein C-terminal 962 1101 1.0E-14 T 12-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 SMART SM00487 340 525 1.2E-16 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 236 306 9.9E-7 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Pfam PF13643 Domain of unknown function (DUF4145) 23 113 1.6E-9 T 12-10-2018 IPR025285 Domain of unknown function DUF4145 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 SUPERFAMILY SSF52540 464 783 2.31E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Pfam PF00271 Helicase conserved C-terminal domain 609 712 3.7E-7 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Gene3D G3DSA:3.90.1570.30 180 326 1.0E-27 T 12-10-2018 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Gene3D G3DSA:3.40.50.300 327 516 2.4E-55 T 12-10-2018 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Gene3D G3DSA:3.40.50.300 524 747 4.2E-59 T 12-10-2018 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 Pfam PF04851 Type III restriction enzyme, res subunit 343 502 1.4E-36 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 NPD12_859 3e2230acc083cec903022a6037e277dd 1115 SUPERFAMILY SSF52540 296 559 4.97E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3409 5df2b93f1fc045002f358040f425ca62 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_3409 5df2b93f1fc045002f358040f425ca62 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_3409 5df2b93f1fc045002f358040f425ca62 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 7.0E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_3409 5df2b93f1fc045002f358040f425ca62 214 SUPERFAMILY SSF46689 18 73 4.69E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3409 5df2b93f1fc045002f358040f425ca62 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 69 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site NPD12_3409 5df2b93f1fc045002f358040f425ca62 214 Gene3D G3DSA:1.10.357.10 16 207 1.6E-28 T 12-10-2018 NPD12_1984 e197761d5929e4ab62f360b8f838ebe5 357 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 6 355 1.3E-122 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 NPD12_1984 e197761d5929e4ab62f360b8f838ebe5 357 Gene3D G3DSA:3.40.50.11750 8 250 2.2E-104 T 12-10-2018 NPD12_1984 e197761d5929e4ab62f360b8f838ebe5 357 Gene3D G3DSA:1.10.10.2140 304 355 1.6E-22 T 12-10-2018 NPD12_1984 e197761d5929e4ab62f360b8f838ebe5 357 Gene3D G3DSA:3.40.50.11740 53 290 2.2E-104 T 12-10-2018 NPD12_1984 e197761d5929e4ab62f360b8f838ebe5 357 Pfam PF01924 Hydrogenase formation hypA family 7 353 3.6E-134 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 NPD12_1984 e197761d5929e4ab62f360b8f838ebe5 357 PIRSF PIRSF005622 1 357 2.3E-130 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 NPD12_2493 788ee1410312ad6e5148ae6298354f0e 240 PIRSF PIRSF000386 1 240 6.7E-102 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 NPD12_2493 788ee1410312ad6e5148ae6298354f0e 240 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 240 103.936 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 NPD12_2493 788ee1410312ad6e5148ae6298354f0e 240 SUPERFAMILY SSF75217 1 238 3.7E-98 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases NPD12_2493 788ee1410312ad6e5148ae6298354f0e 240 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 217 2.6E-61 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 NPD12_2493 788ee1410312ad6e5148ae6298354f0e 240 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 230 2.0E-96 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 NPD12_2493 788ee1410312ad6e5148ae6298354f0e 240 Gene3D G3DSA:1.10.1270.20 160 240 2.8E-33 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 NPD12_2493 788ee1410312ad6e5148ae6298354f0e 240 Gene3D G3DSA:3.40.1280.10 1 159 4.8E-66 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 SUPERFAMILY SSF53223 6 158 6.19E-57 T 12-10-2018 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 Gene3D G3DSA:3.40.50.10380 1 157 2.8E-75 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 Gene3D G3DSA:3.40.50.720 158 389 2.3E-88 T 12-10-2018 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 Pfam PF03949 Malic enzyme, NAD binding domain 162 382 4.5E-29 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 SUPERFAMILY SSF51735 160 389 6.58E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 PIRSF PIRSF000106 20 390 5.9E-88 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 Pfam PF00390 Malic enzyme, N-terminal domain 26 148 6.4E-29 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 SMART SM00919 160 383 3.9E-130 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 NPD12_368 e33a2c84a900b087bade9ad7843237cd 390 SMART SM01274 15 148 7.5E-83 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 NPD12_3621 32d5b9ba045d88bc024006e3773db5eb 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.6E-24 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3621 32d5b9ba045d88bc024006e3773db5eb 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.341 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3621 32d5b9ba045d88bc024006e3773db5eb 59 PIRSF PIRSF002211 1 59 6.2E-27 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3621 32d5b9ba045d88bc024006e3773db5eb 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 53 1.6E-18 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain NPD12_3621 32d5b9ba045d88bc024006e3773db5eb 59 Gene3D G3DSA:3.30.1390.20 1 59 9.9E-25 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily NPD12_3621 32d5b9ba045d88bc024006e3773db5eb 59 SUPERFAMILY SSF55129 4 58 1.44E-19 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily NPD12_47 77fdfb83601080f8e151a38bc1721844 498 Pfam PF11230 Protein of unknown function (DUF3029) 13 495 2.0E-229 T 12-10-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted NPD12_47 77fdfb83601080f8e151a38bc1721844 498 PIRSF PIRSF028991 1 498 2.5E-181 T 12-10-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted NPD12_47 77fdfb83601080f8e151a38bc1721844 498 SUPERFAMILY SSF51998 6 470 7.02E-82 T 12-10-2018 NPD12_47 77fdfb83601080f8e151a38bc1721844 498 TIGRFAM TIGR04040 glycyl_YjjI: glycine radical enzyme, YjjI family 3 495 6.6E-245 T 12-10-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted NPD12_719 c0a3fc4bbf18d22e89b83643a0b71c3a 70 Pfam PF04324 BFD-like [2Fe-2S] binding domain 16 67 1.7E-13 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain NPD12_719 c0a3fc4bbf18d22e89b83643a0b71c3a 70 Gene3D G3DSA:1.10.10.1100 3 70 6.9E-16 T 12-10-2018 NPD12_1664 88a9e61d12615d5c386d9a14b8068c03 392 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 388 6.8E-148 T 12-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 NPD12_1664 88a9e61d12615d5c386d9a14b8068c03 392 Gene3D G3DSA:3.40.640.10 68 292 9.1E-156 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1664 88a9e61d12615d5c386d9a14b8068c03 392 Gene3D G3DSA:3.90.1150.10 13 384 9.1E-156 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1664 88a9e61d12615d5c386d9a14b8068c03 392 Pfam PF00155 Aminotransferase class I and II 36 384 9.9E-43 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1664 88a9e61d12615d5c386d9a14b8068c03 392 SUPERFAMILY SSF53383 1 389 8.47E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_3348 eea1c822c088745da96fc6caace80141 251 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 8 247 35.133 T 12-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit NPD12_3348 eea1c822c088745da96fc6caace80141 251 Gene3D G3DSA:3.40.50.80 102 208 1.8E-19 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_3348 eea1c822c088745da96fc6caace80141 251 Gene3D G3DSA:2.10.240.10 209 247 3.2E-15 T 12-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily NPD12_3348 eea1c822c088745da96fc6caace80141 251 SUPERFAMILY SSF52343 93 245 6.68E-27 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_3348 eea1c822c088745da96fc6caace80141 251 Gene3D G3DSA:2.40.30.10 5 96 5.0E-26 T 12-10-2018 NPD12_3348 eea1c822c088745da96fc6caace80141 251 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 209 245 1.2E-15 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain NPD12_3348 eea1c822c088745da96fc6caace80141 251 PIRSF PIRSF006816 5 251 3.6E-69 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 NPD12_3348 eea1c822c088745da96fc6caace80141 251 SUPERFAMILY SSF63380 7 98 1.13E-20 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel NPD12_1858 e879453ca319cd76a9cad3ab06b892d5 176 Pfam PF08281 Sigma-70, region 4 120 171 2.7E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_1858 e879453ca319cd76a9cad3ab06b892d5 176 Pfam PF04542 Sigma-70 region 2 25 75 1.6E-4 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_1858 e879453ca319cd76a9cad3ab06b892d5 176 SUPERFAMILY SSF88946 2 76 5.76E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_1858 e879453ca319cd76a9cad3ab06b892d5 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 174 1.2E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_1858 e879453ca319cd76a9cad3ab06b892d5 176 Gene3D G3DSA:1.10.10.10 39 176 5.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1858 e879453ca319cd76a9cad3ab06b892d5 176 SUPERFAMILY SSF88659 103 175 1.87E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_1206 0434d7ae292b470a3cafd5ad5792a8fe 174 Pfam PF01047 MarR family 64 122 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1206 0434d7ae292b470a3cafd5ad5792a8fe 174 SMART SM00347 57 160 3.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1206 0434d7ae292b470a3cafd5ad5792a8fe 174 Gene3D G3DSA:1.10.10.10 3 174 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1206 0434d7ae292b470a3cafd5ad5792a8fe 174 SUPERFAMILY SSF46785 62 172 5.06E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 397 51.463 T 12-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 Gene3D G3DSA:3.90.1260.10 63 349 1.3E-150 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 Gene3D G3DSA:3.40.50.620 5 172 1.3E-150 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 SUPERFAMILY SSF52402 2 165 9.26E-45 T 12-10-2018 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 Pfam PF00764 Arginosuccinate synthase 6 391 1.1E-158 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 Gene3D G3DSA:1.20.5.470 373 396 1.9E-6 T 12-10-2018 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 SUPERFAMILY SSF69864 171 395 9.03E-89 T 12-10-2018 NPD12_2719 0235269f0e9fe6ce1f9eda0510a35d1e 397 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 1.9E-150 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Gene3D G3DSA:3.30.420.40 417 560 1.1E-82 T 12-10-2018 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 673 891 3.9E-79 T 12-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Gene3D G3DSA:3.30.420.40 98 242 3.4E-69 T 12-10-2018 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 323 576 2.1E-39 T 12-10-2018 IPR008275 CoA enzyme activase NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 SUPERFAMILY SSF53067 322 577 5.71E-54 T 12-10-2018 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 7 255 3.5E-21 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 323 577 1.0E-35 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Gene3D G3DSA:3.30.420.40 323 577 1.1E-82 T 12-10-2018 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 906 1226 7.4E-57 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 Gene3D G3DSA:3.30.420.40 7 255 3.4E-69 T 12-10-2018 NPD12_1322 3dd4c0078beee10e95aa2b4e72a27d42 1429 SUPERFAMILY SSF53067 7 255 2.28E-56 T 12-10-2018 NPD12_477 2b8355a18e6038a2bbdd5157943f63d1 276 SUPERFAMILY SSF52540 4 230 5.97E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_477 2b8355a18e6038a2bbdd5157943f63d1 276 Gene3D G3DSA:3.40.50.300 1 257 2.3E-69 T 12-10-2018 NPD12_477 2b8355a18e6038a2bbdd5157943f63d1 276 SMART SM00382 28 217 1.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_477 2b8355a18e6038a2bbdd5157943f63d1 276 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_477 2b8355a18e6038a2bbdd5157943f63d1 276 Pfam PF00005 ABC transporter 20 167 1.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1192 1aa645c8e3cb39747f5ecd5f1c72173f 201 PIRSF PIRSF000368 1 166 1.2E-46 T 12-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 NPD12_1192 1aa645c8e3cb39747f5ecd5f1c72173f 201 Pfam PF13353 4Fe-4S single cluster domain 14 148 1.7E-36 T 12-10-2018 NPD12_1192 1aa645c8e3cb39747f5ecd5f1c72173f 201 Pfam PF04055 Radical SAM superfamily 25 109 4.5E-7 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_1192 1aa645c8e3cb39747f5ecd5f1c72173f 201 Gene3D G3DSA:3.20.20.70 2 181 1.8E-33 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1192 1aa645c8e3cb39747f5ecd5f1c72173f 201 SUPERFAMILY SSF102114 26 102 1.06E-10 T 12-10-2018 NPD12_3573 b849c1280e17b5c59767f3edb5010be8 334 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 5 332 1.4E-146 T 12-10-2018 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198 NPD12_3573 b849c1280e17b5c59767f3edb5010be8 334 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 240 332 8.0E-47 T 12-10-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198 NPD12_3573 b849c1280e17b5c59767f3edb5010be8 334 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 6 185 7.5E-77 T 12-10-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198 NPD12_2171 bc6431ca9dbbe40580d0b6b2ffa035a3 265 SUPERFAMILY SSF55797 138 264 2.49E-29 T 12-10-2018 IPR035940 CAP superfamily NPD12_2171 bc6431ca9dbbe40580d0b6b2ffa035a3 265 Pfam PF00188 Cysteine-rich secretory protein family 145 260 1.1E-23 T 12-10-2018 IPR014044 CAP domain NPD12_2171 bc6431ca9dbbe40580d0b6b2ffa035a3 265 Gene3D G3DSA:3.40.33.10 8 262 1.7E-65 T 12-10-2018 IPR035940 CAP superfamily NPD12_2171 bc6431ca9dbbe40580d0b6b2ffa035a3 265 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 137 262 3.2E-62 T 12-10-2018 IPR014258 CAP domain, YkwD-like NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 Gene3D G3DSA:3.30.40.60 486 579 9.0E-7 T 12-10-2018 NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 Gene3D G3DSA:3.30.70.270 267 345 2.8E-5 T 12-10-2018 NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 SMART SM00507 503 557 3.2E-12 T 12-10-2018 IPR003615 HNH nuclease NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 Pfam PF08388 Group II intron, maturase-specific domain 358 436 1.4E-16 T 12-10-2018 IPR013597 Group II intron, maturase-specific NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 Pfam PF13655 N-terminal domain of reverse transcriptase 19 98 2.4E-26 T 12-10-2018 IPR025960 Reverse transcriptase, N-terminal domain NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 62 420 3.0E-111 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 Pfam PF01844 HNH endonuclease 516 561 7.8E-10 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 119 338 1.5E-46 T 12-10-2018 IPR000477 Reverse transcriptase domain NPD12_2416 217e7b87c15d4bae46cdf178171ca82a 608 SUPERFAMILY SSF56672 96 362 1.68E-47 T 12-10-2018 NPD12_315 fd35a238c255645861b0f05edd5720aa 358 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 14 352 8.0E-114 T 12-10-2018 IPR014225 Sporulation stage II, protein D firmicutes NPD12_315 fd35a238c255645861b0f05edd5720aa 358 Pfam PF08486 Stage II sporulation protein 81 185 7.8E-28 T 12-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal NPD12_315 fd35a238c255645861b0f05edd5720aa 358 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 82 351 3.7E-78 T 12-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 NPD12_1761 718d9f23f199840739773186fce3aa46 453 Gene3D G3DSA:3.40.190.10 169 439 1.1E-89 T 12-10-2018 NPD12_1761 718d9f23f199840739773186fce3aa46 453 SUPERFAMILY SSF53850 47 440 3.21E-76 T 12-10-2018 NPD12_1761 718d9f23f199840739773186fce3aa46 453 Pfam PF13416 Bacterial extracellular solute-binding protein 66 382 4.1E-45 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein NPD12_1761 718d9f23f199840739773186fce3aa46 453 Gene3D G3DSA:3.40.190.10 51 403 1.1E-89 T 12-10-2018 NPD12_2354 e2ca38b1992bdae33e269e424c619e84 651 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 36 596 4.6E-93 T 12-10-2018 IPR004814 Oligopeptide transporter OPT NPD12_2354 e2ca38b1992bdae33e269e424c619e84 651 Pfam PF03169 OPT oligopeptide transporter protein 35 597 4.8E-90 T 12-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 NPD12_1896 b19ec9accdd57995c204934804534254 81 SUPERFAMILY SSF46689 2 80 2.2E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1896 b19ec9accdd57995c204934804534254 81 Pfam PF02954 Bacterial regulatory protein, Fis family 54 81 6.4E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1896 b19ec9accdd57995c204934804534254 81 Gene3D G3DSA:1.10.8.60 1 42 1.7E-6 T 12-10-2018 NPD12_1896 b19ec9accdd57995c204934804534254 81 Gene3D G3DSA:1.10.10.60 47 81 1.2E-6 T 12-10-2018 NPD12_491 2680d376bfb2004a8d9bdd5a46a437dd 297 SUPERFAMILY SSF102114 23 210 1.44E-9 T 12-10-2018 NPD12_491 2680d376bfb2004a8d9bdd5a46a437dd 297 SMART SM00729 22 242 0.005 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_491 2680d376bfb2004a8d9bdd5a46a437dd 297 Pfam PF04055 Radical SAM superfamily 26 190 4.4E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3105 bfcaa7c8dc858eb37d9095080a911c47 924 Pfam PF03717 Penicillin-binding Protein dimerisation domain 55 329 4.2E-51 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 NPD12_3105 bfcaa7c8dc858eb37d9095080a911c47 924 Gene3D G3DSA:3.90.1310.10 45 338 1.4E-34 T 12-10-2018 NPD12_3105 bfcaa7c8dc858eb37d9095080a911c47 924 SUPERFAMILY SSF56601 295 882 8.45E-78 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_3105 bfcaa7c8dc858eb37d9095080a911c47 924 Gene3D G3DSA:1.10.10.1230 78 255 1.4E-34 T 12-10-2018 NPD12_3105 bfcaa7c8dc858eb37d9095080a911c47 924 SUPERFAMILY SSF56519 47 343 1.2E-37 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 NPD12_3105 bfcaa7c8dc858eb37d9095080a911c47 924 Pfam PF00905 Penicillin binding protein transpeptidase domain 380 876 5.8E-52 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 NPD12_629 da930aa9a926538855d53ffff7537935 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 3.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_629 da930aa9a926538855d53ffff7537935 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 3.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_629 da930aa9a926538855d53ffff7537935 483 Gene3D G3DSA:1.10.10.10 2 87 1.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_629 da930aa9a926538855d53ffff7537935 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 3.1E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_629 da930aa9a926538855d53ffff7537935 483 Gene3D G3DSA:3.90.1150.10 115 473 3.3E-98 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_629 da930aa9a926538855d53ffff7537935 483 Gene3D G3DSA:3.40.640.10 153 373 3.3E-98 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_629 da930aa9a926538855d53ffff7537935 483 SUPERFAMILY SSF53383 114 479 1.86E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_629 da930aa9a926538855d53ffff7537935 483 Pfam PF00155 Aminotransferase class I and II 132 466 1.3E-32 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_629 da930aa9a926538855d53ffff7537935 483 SMART SM00345 17 76 6.8E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_629 da930aa9a926538855d53ffff7537935 483 SUPERFAMILY SSF46785 7 84 6.07E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_284 538c4c3d92bd741e7a9a88048aba4a79 142 Gene3D G3DSA:2.40.128.20 1 141 2.5E-35 T 12-10-2018 IPR012674 Calycin NPD12_284 538c4c3d92bd741e7a9a88048aba4a79 142 Pfam PF09148 Domain of unknown function (DUF1934) 10 134 5.9E-36 T 12-10-2018 IPR015231 Protein of unknown function DUF1934 NPD12_284 538c4c3d92bd741e7a9a88048aba4a79 142 SUPERFAMILY SSF50814 7 137 6.5E-30 T 12-10-2018 IPR012674 Calycin NPD12_479 6c67c85a996a2f10a18a555580862094 126 SMART SM00529 26 126 4.0E-22 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 NPD12_479 6c67c85a996a2f10a18a555580862094 126 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 124 1.0E-15 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 NPD12_479 6c67c85a996a2f10a18a555580862094 126 SUPERFAMILY SSF46785 4 64 4.1E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_479 6c67c85a996a2f10a18a555580862094 126 Gene3D G3DSA:1.10.10.10 1 68 1.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_479 6c67c85a996a2f10a18a555580862094 126 Gene3D G3DSA:1.10.60.10 69 126 5.1E-18 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 NPD12_479 6c67c85a996a2f10a18a555580862094 126 SUPERFAMILY SSF47979 65 122 6.15E-16 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 NPD12_479 6c67c85a996a2f10a18a555580862094 126 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 60 2.6E-13 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 NPD12_131 6fa388673b01b1674f2994eac5da059b 364 Gene3D G3DSA:1.20.1050.90 120 304 5.0E-105 T 12-10-2018 NPD12_131 6fa388673b01b1674f2994eac5da059b 364 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 NPD12_131 6fa388673b01b1674f2994eac5da059b 364 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 337 1.9E-14 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal NPD12_131 6fa388673b01b1674f2994eac5da059b 364 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 364 91.017 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 NPD12_131 6fa388673b01b1674f2994eac5da059b 364 ProSitePatterns PS00618 RecF protein signature 2. 305 323 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 NPD12_131 6fa388673b01b1674f2994eac5da059b 364 Gene3D G3DSA:3.40.50.300 7 337 5.0E-105 T 12-10-2018 NPD12_131 6fa388673b01b1674f2994eac5da059b 364 SUPERFAMILY SSF52540 1 363 8.24E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_131 6fa388673b01b1674f2994eac5da059b 364 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 360 1.2E-105 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 SUPERFAMILY SSF55920 45 289 6.93E-75 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 Hamap MF_01974 Methionine aminopeptidase [map]. 45 291 34.593 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 Gene3D G3DSA:3.10.450.50 1 22 3.0E-6 T 12-10-2018 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 46 290 2.7E-80 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 SUPERFAMILY SSF103642 6 26 1.64E-7 T 12-10-2018 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 Pfam PF02810 SEC-C motif 7 23 8.8E-10 T 12-10-2018 IPR004027 SEC-C motif NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 202 214 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 109 122 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 233 245 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 132 148 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 Pfam PF00557 Metallopeptidase family M24 55 282 3.1E-48 T 12-10-2018 IPR000994 Peptidase M24 NPD12_45 bdfb44cd9f28975c806a419af26646c6 291 Gene3D G3DSA:3.90.230.10 23 291 2.4E-91 T 12-10-2018 NPD12_2968 ad96d351df5b3af7a3badf7672bd1926 285 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2968 ad96d351df5b3af7a3badf7672bd1926 285 SMART SM00382 28 207 4.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2968 ad96d351df5b3af7a3badf7672bd1926 285 Gene3D G3DSA:3.40.50.300 4 225 1.9E-47 T 12-10-2018 NPD12_2968 ad96d351df5b3af7a3badf7672bd1926 285 Pfam PF00005 ABC transporter 20 158 2.0E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2968 ad96d351df5b3af7a3badf7672bd1926 285 SUPERFAMILY SSF52540 2 223 6.41E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 SUPERFAMILY SSF55781 49 187 3.92E-5 T 12-10-2018 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 413 428 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 SUPERFAMILY SSF55785 192 301 6.63E-13 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 617 636 8.4E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 600 617 8.4E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Gene3D G3DSA:1.10.8.60 498 562 9.1E-17 T 12-10-2018 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Gene3D G3DSA:1.10.10.60 592 636 6.8E-16 T 12-10-2018 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 SUPERFAMILY SSF46689 540 636 5.97E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Pfam PF02954 Bacterial regulatory protein, Fis family 593 634 9.1E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 SUPERFAMILY SSF52540 325 561 1.85E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Pfam PF00158 Sigma-54 interaction domain 326 494 3.7E-70 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 SMART SM00091 200 268 2.4E-6 T 12-10-2018 IPR000014 PAS domain NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 350 363 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Gene3D G3DSA:3.30.450.20 188 304 9.3E-20 T 12-10-2018 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 202 261 6.3E-7 T 12-10-2018 IPR000014 PAS domain NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Gene3D G3DSA:3.40.50.300 312 497 1.7E-68 T 12-10-2018 NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Pfam PF13188 PAS domain 202 257 4.8E-7 T 12-10-2018 IPR000014 PAS domain NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 Gene3D G3DSA:3.30.450.40 3 187 3.7E-55 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_1881 fa46508a1ac1b1d5b26ece64de5155dc 636 SMART SM00382 346 490 3.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 PRINTS PR00069 Aldo-keto reductase signature 195 219 3.8E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 PRINTS PR00069 Aldo-keto reductase signature 158 187 3.8E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 PRINTS PR00069 Aldo-keto reductase signature 95 113 3.8E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 PRINTS PR00069 Aldo-keto reductase signature 124 141 3.8E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 PRINTS PR00069 Aldo-keto reductase signature 39 63 3.8E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 PIRSF PIRSF000097 116 277 5.3E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 PIRSF PIRSF000097 1 120 8.3E-40 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 Gene3D G3DSA:3.20.20.100 2 274 1.7E-115 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 Pfam PF00248 Aldo/keto reductase family 19 260 4.4E-53 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain NPD12_1170 b6605bf80193d2d70a55a6cdaa1b0c53 281 SUPERFAMILY SSF51430 6 267 5.63E-94 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_2586 6beb9e65ab5056ef202f4729a4abc113 350 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 12-10-2018 IPR001482 Type II/IV secretion system protein NPD12_2586 6beb9e65ab5056ef202f4729a4abc113 350 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 341 3.0E-142 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 NPD12_2586 6beb9e65ab5056ef202f4729a4abc113 350 SUPERFAMILY SSF52540 4 336 5.04E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2586 6beb9e65ab5056ef202f4729a4abc113 350 SMART SM00382 122 247 4.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2586 6beb9e65ab5056ef202f4729a4abc113 350 Pfam PF00437 Type II/IV secretion system protein 90 270 5.8E-41 T 12-10-2018 IPR001482 Type II/IV secretion system protein NPD12_2586 6beb9e65ab5056ef202f4729a4abc113 350 Gene3D G3DSA:3.40.50.300 101 349 1.7E-97 T 12-10-2018 NPD12_2586 6beb9e65ab5056ef202f4729a4abc113 350 Gene3D G3DSA:3.30.450.90 1 100 1.4E-31 T 12-10-2018 NPD12_3166 306fc912cc5d21a29b281e532a6ee8af 199 SUPERFAMILY SSF56281 1 199 1.28E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_3166 306fc912cc5d21a29b281e532a6ee8af 199 Pfam PF00753 Metallo-beta-lactamase superfamily 12 183 2.6E-27 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_3166 306fc912cc5d21a29b281e532a6ee8af 199 SMART SM00849 12 183 3.4E-43 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_3166 306fc912cc5d21a29b281e532a6ee8af 199 Gene3D G3DSA:3.60.15.10 1 199 7.9E-64 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 TIGRFAM TIGR04119 CXXX_matur: CXXX repeat peptide maturase 496 701 1.3E-80 T 12-10-2018 IPR026401 CXXX repeat peptide maturase NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 26 37 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 TIGRFAM TIGR04115 rSAM_Cxxx_rpt: radical SAM peptide maturase, CXXX-repeat target family 21 377 2.9E-156 T 12-10-2018 IPR026412 Radical SAM peptide maturase, CXXX-repeat target NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 270 357 1.6E-7 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 Gene3D G3DSA:3.20.20.70 455 675 3.3E-5 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 Gene3D G3DSA:3.20.20.70 19 378 6.9E-57 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 SUPERFAMILY SSF102114 22 340 2.62E-33 T 12-10-2018 NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 Pfam PF04055 Radical SAM superfamily 26 179 5.8E-8 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3474 0b935e23f403aec96ee1d3e88c127559 715 Pfam PF13353 4Fe-4S single cluster domain 22 163 1.8E-8 T 12-10-2018 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 SUPERFAMILY SSF55874 305 448 7.07E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 SUPERFAMILY SSF47384 215 293 8.83E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 Gene3D G3DSA:1.10.287.130 236 295 4.7E-8 T 12-10-2018 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 288 6.4E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 SMART SM00387 341 451 1.4E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 SMART SM00388 230 294 9.8E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 448 1.5E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 Gene3D G3DSA:3.30.565.10 300 451 1.3E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 Gene3D G3DSA:1.20.1480.50 143 235 9.2E-7 T 12-10-2018 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 449 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1228 73d81e867ad09256c0d2e85802bd4624 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2132 fbc87d78f23ec24d75e32fdda42864a9 271 Pfam PF02596 Uncharacterised ArCR, COG2043 29 238 5.9E-52 T 12-10-2018 IPR003748 Protein of unknown function DUF169 NPD12_1910 ae6c302796556c7de0f76ee0ece93e95 531 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 94 116 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site NPD12_1910 ae6c302796556c7de0f76ee0ece93e95 531 PIRSF PIRSF002741 3 525 1.7E-86 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 NPD12_1910 ae6c302796556c7de0f76ee0ece93e95 531 SUPERFAMILY SSF53850 54 519 5.83E-106 T 12-10-2018 NPD12_1910 ae6c302796556c7de0f76ee0ece93e95 531 Gene3D G3DSA:3.40.190.10 68 501 4.7E-105 T 12-10-2018 NPD12_1910 ae6c302796556c7de0f76ee0ece93e95 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 442 1.8E-74 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain NPD12_1910 ae6c302796556c7de0f76ee0ece93e95 531 Gene3D G3DSA:3.10.105.10 286 496 4.7E-105 T 12-10-2018 NPD12_1910 ae6c302796556c7de0f76ee0ece93e95 531 Gene3D G3DSA:3.90.76.10 78 195 4.7E-105 T 12-10-2018 NPD12_3498 a6d5c31ad2db72a960caa00ba71dc765 331 Pfam PF03984 Repeat of unknown function (DUF346) 182 216 9.9E-7 T 12-10-2018 IPR007132 Protein of unknown function DUF346 NPD12_3498 a6d5c31ad2db72a960caa00ba71dc765 331 Pfam PF03984 Repeat of unknown function (DUF346) 226 260 4.7E-8 T 12-10-2018 IPR007132 Protein of unknown function DUF346 NPD12_3498 a6d5c31ad2db72a960caa00ba71dc765 331 Pfam PF03984 Repeat of unknown function (DUF346) 136 171 2.1E-7 T 12-10-2018 IPR007132 Protein of unknown function DUF346 NPD12_3498 a6d5c31ad2db72a960caa00ba71dc765 331 SUPERFAMILY SSF89372 61 164 1.57E-24 T 12-10-2018 NPD12_3498 a6d5c31ad2db72a960caa00ba71dc765 331 Gene3D G3DSA:2.120.10.70 76 319 2.1E-11 T 12-10-2018 NPD12_3498 a6d5c31ad2db72a960caa00ba71dc765 331 SUPERFAMILY SSF89372 155 330 4.58E-42 T 12-10-2018 NPD12_1550 3e3c2c11c3ac2f57a7e6463f97aa4d40 267 Pfam PF10997 Alternate to MurJ 11 263 5.0E-98 T 12-10-2018 IPR021260 Lipid II flippase Amj NPD12_1550 3e3c2c11c3ac2f57a7e6463f97aa4d40 267 Hamap MF_02077 Lipid II flippase Amj [amj]. 2 265 27.608 T 12-10-2018 IPR021260 Lipid II flippase Amj NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Pfam PF00012 Hsp70 protein 79 576 1.2E-221 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Pfam PF00012 Hsp70 protein 4 78 1.3E-30 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 SUPERFAMILY SSF100934 479 577 5.49E-14 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 SUPERFAMILY SSF53067 2 159 1.08E-59 T 12-10-2018 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Gene3D G3DSA:1.20.1270.10 497 579 1.0E-24 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Gene3D G3DSA:2.60.34.10 355 496 6.3E-62 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 441 457 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 360 379 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 337 357 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 54 62 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 174 184 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 306 322 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 PRINTS PR00301 70kDa heat shock protein signature 114 134 5.2E-80 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 SUPERFAMILY SSF100920 356 512 1.27E-60 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 SUPERFAMILY SSF53067 163 354 9.86E-68 T 12-10-2018 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Gene3D G3DSA:3.90.640.10 201 288 6.2E-145 T 12-10-2018 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Gene3D G3DSA:3.30.420.40 5 351 6.2E-145 T 12-10-2018 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 620 37.267 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 309 323 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 576 3.2E-289 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 NPD12_3008 3b6a59d4692d8193acbad584f05f8c10 623 Gene3D G3DSA:3.30.420.40 156 338 6.2E-145 T 12-10-2018 NPD12_2231 3f83377d343b32f9bf5b19c76daaefb1 449 Pfam PF00535 Glycosyl transferase family 2 13 181 8.0E-35 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_2231 3f83377d343b32f9bf5b19c76daaefb1 449 Pfam PF00535 Glycosyl transferase family 2 252 377 4.5E-13 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_2231 3f83377d343b32f9bf5b19c76daaefb1 449 Gene3D G3DSA:3.90.550.10 250 449 2.8E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2231 3f83377d343b32f9bf5b19c76daaefb1 449 SUPERFAMILY SSF53448 11 231 8.66E-49 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2231 3f83377d343b32f9bf5b19c76daaefb1 449 SUPERFAMILY SSF53448 251 448 2.16E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2231 3f83377d343b32f9bf5b19c76daaefb1 449 Gene3D G3DSA:3.90.550.10 4 248 1.2E-47 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2959 00e11e02e494805023c56e22d5b7c40e 543 Gene3D G3DSA:3.40.630.10 1 226 1.2E-31 T 12-10-2018 NPD12_2959 00e11e02e494805023c56e22d5b7c40e 543 PIRSF PIRSF010386 1 543 1.1E-176 T 12-10-2018 IPR012166 Uncharacterised protein family RocB NPD12_2959 00e11e02e494805023c56e22d5b7c40e 543 SUPERFAMILY SSF53187 4 541 4.72E-29 T 12-10-2018 NPD12_2959 00e11e02e494805023c56e22d5b7c40e 543 Pfam PF01546 Peptidase family M20/M25/M40 81 417 2.4E-13 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_1180 53b94b1440092d6f0d065a0568773d1a 331 Gene3D G3DSA:3.20.20.140 2 330 1.4E-104 T 12-10-2018 NPD12_1180 53b94b1440092d6f0d065a0568773d1a 331 Hamap MF_00540 Adenosine deaminase [add]. 1 331 58.367 T 12-10-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 NPD12_1180 53b94b1440092d6f0d065a0568773d1a 331 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 6 327 1.0E-93 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 NPD12_1180 53b94b1440092d6f0d065a0568773d1a 331 Pfam PF00962 Adenosine/AMP deaminase 6 326 1.0E-72 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 NPD12_1180 53b94b1440092d6f0d065a0568773d1a 331 SUPERFAMILY SSF51556 3 328 7.9E-85 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_70 208fd636c45e333c1f335cf9b350deee 314 SUPERFAMILY SSF52151 4 309 1.78E-74 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase NPD12_70 208fd636c45e333c1f335cf9b350deee 314 SUPERFAMILY SSF55048 129 196 9.42E-17 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding NPD12_70 208fd636c45e333c1f335cf9b350deee 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 1.1E-98 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 NPD12_70 208fd636c45e333c1f335cf9b350deee 314 Pfam PF00698 Acyl transferase domain 6 286 4.6E-34 T 12-10-2018 IPR014043 Acyl transferase NPD12_70 208fd636c45e333c1f335cf9b350deee 314 Gene3D G3DSA:3.30.70.250 126 196 3.6E-94 T 12-10-2018 NPD12_70 208fd636c45e333c1f335cf9b350deee 314 PIRSF PIRSF000446 1 310 1.2E-101 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 NPD12_70 208fd636c45e333c1f335cf9b350deee 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 306 6.1E-34 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain NPD12_70 208fd636c45e333c1f335cf9b350deee 314 Gene3D G3DSA:3.40.366.10 5 285 3.6E-94 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 NPD12_452 0ffb4adc18c072cb167941c58e29bd30 212 Gene3D G3DSA:3.40.50.720 1 211 4.6E-50 T 12-10-2018 NPD12_452 0ffb4adc18c072cb167941c58e29bd30 212 Pfam PF13460 NAD(P)H-binding 7 200 8.9E-30 T 12-10-2018 IPR016040 NAD(P)-binding domain NPD12_452 0ffb4adc18c072cb167941c58e29bd30 212 SUPERFAMILY SSF51735 1 210 2.01E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 110 290 5.3E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 SMART SM00283 63 324 3.6E-42 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 Gene3D G3DSA:3.90.76.10 358 508 8.4E-105 T 12-10-2018 NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 391 413 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 SUPERFAMILY SSF53850 345 821 1.43E-100 T 12-10-2018 NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 Gene3D G3DSA:3.40.190.10 509 813 8.4E-105 T 12-10-2018 NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 Gene3D G3DSA:1.10.287.950 33 336 5.9E-55 T 12-10-2018 NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 SUPERFAMILY SSF58104 33 334 3.14E-58 T 12-10-2018 NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 385 744 5.3E-67 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain NPD12_1001 5cc0b399c9dfee6473ead700f012d454 826 Gene3D G3DSA:3.10.105.10 587 801 8.4E-105 T 12-10-2018 NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 Gene3D G3DSA:3.40.50.300 404 628 9.2E-19 T 12-10-2018 NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 Gene3D G3DSA:1.10.8.630 8 120 8.2E-19 T 12-10-2018 NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 SMART SM00490 495 592 1.7E-9 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 734 24.107 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 SMART SM00487 197 392 7.4E-22 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 SUPERFAMILY SSF52540 212 600 1.32E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 Pfam PF00271 Helicase conserved C-terminal domain 496 591 1.1E-8 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 Pfam PF00270 DEAD/DEAH box helicase 205 362 8.6E-14 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 Gene3D G3DSA:3.40.50.300 187 379 1.4E-66 T 12-10-2018 NPD12_2558 ace87638eb2efa6baf957b1217fd6d55 735 TIGRFAM TIGR00595 priA: primosomal protein N' 221 731 5.6E-204 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 NPD12_2217 1c8a80d810d7b5fd6f5e3d4e6f8a1441 423 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 17 384 4.4E-54 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 NPD12_2217 1c8a80d810d7b5fd6f5e3d4e6f8a1441 423 Gene3D G3DSA:1.10.4160.10 9 422 1.7E-51 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 Gene3D G3DSA:3.40.50.720 4 169 6.2E-57 T 12-10-2018 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 Gene3D G3DSA:3.90.110.10 170 444 2.5E-98 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 419 3.1E-50 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 SUPERFAMILY SSF51735 6 166 3.53E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 Pfam PF02056 Family 4 glycosyl hydrolase 8 187 1.9E-62 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 SUPERFAMILY SSF56327 171 444 6.95E-90 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 8.3E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 8.3E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 8 23 8.3E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 8.3E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 8.3E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 8.3E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 8.3E-56 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_455 8c2b6de35895268ef7cd6cd889e1c49b 444 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 12-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 SMART SM00283 280 528 2.6E-25 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 SUPERFAMILY SSF103190 61 179 1.36E-18 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 Gene3D G3DSA:1.10.287.950 234 563 3.3E-51 T 12-10-2018 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 414 443 1.0E-16 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 385 412 1.0E-16 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.0E-16 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 348 513 1.6E-26 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 SUPERFAMILY SSF58104 233 563 5.14E-53 T 12-10-2018 NPD12_2836 371d06fcce4625deca2a4ef1984fd9ee 564 Pfam PF17202 Single cache domain 3 74 176 3.5E-36 T 12-10-2018 IPR033463 Single cache domain 3 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 SUPERFAMILY SSF55973 241 389 3.57E-69 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 124 134 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 Gene3D G3DSA:3.30.300.10 10 278 8.2E-179 T 12-10-2018 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 PIRSF PIRSF000497 1 391 1.1E-176 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 Gene3D G3DSA:3.30.300.10 101 383 8.2E-179 T 12-10-2018 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 SUPERFAMILY SSF55973 3 108 6.67E-48 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 391 58.269 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 4 390 6.2E-186 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 Pfam PF02772 S-adenosylmethionine synthetase, central domain 123 239 1.8E-50 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 Gene3D G3DSA:3.30.300.10 4 241 8.2E-179 T 12-10-2018 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 380 1.4E-70 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 SUPERFAMILY SSF55973 119 240 2.51E-53 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_326 99aba894994d4ad4f0840ea6d50891ef 391 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 99 2.4E-44 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 NPD12_1036 ff5776751e305f1efbef81cb5228eadb 166 Gene3D G3DSA:3.30.460.10 1 166 4.9E-62 T 12-10-2018 NPD12_1036 ff5776751e305f1efbef81cb5228eadb 166 SUPERFAMILY SSF81301 5 165 4.25E-55 T 12-10-2018 NPD12_1036 ff5776751e305f1efbef81cb5228eadb 166 Pfam PF04229 GrpB protein 2 162 3.2E-53 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase NPD12_2169 04b456356cff4114aacc059fde99d098 591 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 305 318 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_2169 04b456356cff4114aacc059fde99d098 591 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 368 383 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_2169 04b456356cff4114aacc059fde99d098 591 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 495 504 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_2169 04b456356cff4114aacc059fde99d098 591 Gene3D G3DSA:3.30.450.20 164 260 4.9E-10 T 12-10-2018 NPD12_2169 04b456356cff4114aacc059fde99d098 591 SUPERFAMILY SSF46689 495 589 9.5E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2169 04b456356cff4114aacc059fde99d098 591 SMART SM00382 301 445 3.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2169 04b456356cff4114aacc059fde99d098 591 SUPERFAMILY SSF52540 280 525 5.32E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2169 04b456356cff4114aacc059fde99d098 591 Gene3D G3DSA:1.10.8.60 454 535 1.5E-23 T 12-10-2018 NPD12_2169 04b456356cff4114aacc059fde99d098 591 Gene3D G3DSA:3.40.50.300 267 453 3.3E-65 T 12-10-2018 NPD12_2169 04b456356cff4114aacc059fde99d098 591 Pfam PF00158 Sigma-54 interaction domain 281 448 2.6E-68 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_2169 04b456356cff4114aacc059fde99d098 591 Gene3D G3DSA:1.10.10.60 543 589 2.7E-8 T 12-10-2018 NPD12_1349 863ea70170a97e9b49fccd39ee0b5a5e 335 SUPERFAMILY SSF53822 46 294 3.26E-13 T 12-10-2018 IPR028082 Periplasmic binding protein-like I NPD12_1349 863ea70170a97e9b49fccd39ee0b5a5e 335 Gene3D G3DSA:3.40.50.2300 56 302 4.1E-90 T 12-10-2018 NPD12_1349 863ea70170a97e9b49fccd39ee0b5a5e 335 Gene3D G3DSA:3.40.50.2300 153 323 4.1E-90 T 12-10-2018 NPD12_1349 863ea70170a97e9b49fccd39ee0b5a5e 335 Pfam PF04392 ABC transporter substrate binding protein 40 330 5.8E-88 T 12-10-2018 IPR007487 ABC transporter, substrate-binding protein NPD12_796 a638590d8e6449230033c11532041309 208 Pfam PF00302 Chloramphenicol acetyltransferase 2 201 2.1E-42 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_796 a638590d8e6449230033c11532041309 208 PIRSF PIRSF000440 1 208 6.2E-63 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_796 a638590d8e6449230033c11532041309 208 SMART SM01059 1 201 1.6E-96 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_796 a638590d8e6449230033c11532041309 208 Gene3D G3DSA:3.30.559.10 1 205 2.7E-62 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 NPD12_796 a638590d8e6449230033c11532041309 208 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 11 200 1.0E-74 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_796 a638590d8e6449230033c11532041309 208 SUPERFAMILY SSF52777 2 206 1.42E-54 T 12-10-2018 NPD12_2144 4f38500b57e890fc220e6a0bc73639e4 326 Pfam PF12345 Protein of unknown function (DUF3641) 192 324 8.6E-55 T 12-10-2018 IPR024521 Domain of unknown function DUF3641 NPD12_2144 4f38500b57e890fc220e6a0bc73639e4 326 TIGRFAM TIGR04167 rSAM_SeCys: radical SAM/Cys-rich domain protein 29 324 2.1E-136 T 12-10-2018 IPR026351 Radical SAM/Cys-rich domain protein NPD12_2144 4f38500b57e890fc220e6a0bc73639e4 326 Pfam PF13353 4Fe-4S single cluster domain 43 135 5.3E-5 T 12-10-2018 NPD12_2144 4f38500b57e890fc220e6a0bc73639e4 326 Gene3D G3DSA:3.20.20.70 27 295 1.3E-24 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2144 4f38500b57e890fc220e6a0bc73639e4 326 SUPERFAMILY SSF102114 32 322 6.08E-40 T 12-10-2018 NPD12_2144 4f38500b57e890fc220e6a0bc73639e4 326 Pfam PF04055 Radical SAM superfamily 37 175 3.7E-8 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 Hamap MF_00815 ATP synthase gamma chain [atpG]. 3 281 29.146 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 Pfam PF00231 ATP synthase 8 280 2.4E-81 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 SUPERFAMILY SSF52943 5 280 3.4E-76 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 Gene3D G3DSA:3.40.1380.10 62 200 6.4E-84 T 12-10-2018 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 267 280 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 Gene3D G3DSA:1.10.287.80 9 277 6.4E-84 T 12-10-2018 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 PRINTS PR00126 ATP synthase gamma subunit signature 228 247 2.9E-29 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 PRINTS PR00126 ATP synthase gamma subunit signature 164 181 2.9E-29 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 PRINTS PR00126 ATP synthase gamma subunit signature 259 280 2.9E-29 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.9E-29 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_310 c66c21e86c0d8c85c828779c84927e06 282 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 6 280 6.0E-78 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_1587 ef356ae47ea93238b8cc0800e2af3976 486 Pfam PF04122 Putative cell wall binding repeat 2 240 323 7.3E-19 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_1587 ef356ae47ea93238b8cc0800e2af3976 486 Pfam PF04122 Putative cell wall binding repeat 2 135 222 8.7E-13 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_1587 ef356ae47ea93238b8cc0800e2af3976 486 Pfam PF04122 Putative cell wall binding repeat 2 31 118 2.6E-21 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_1587 ef356ae47ea93238b8cc0800e2af3976 486 Gene3D G3DSA:3.40.50.12090 53 153 5.2E-5 T 12-10-2018 NPD12_1587 ef356ae47ea93238b8cc0800e2af3976 486 Gene3D G3DSA:3.40.50.12090 173 258 1.2E-7 T 12-10-2018 NPD12_1587 ef356ae47ea93238b8cc0800e2af3976 486 Pfam PF16800 IseA DL-endopeptidase inhibitor 332 482 2.5E-44 T 12-10-2018 IPR031841 DL-endopeptidase inhibitor IseA NPD12_2013 6fb04acea14c098b5e706716c589d171 240 Pfam PF12787 EcsC protein family 9 236 1.7E-68 T 12-10-2018 IPR024787 EcsC protein NPD12_2013 6fb04acea14c098b5e706716c589d171 240 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 235 1.0E-44 T 12-10-2018 NPD12_1831 7022bc363278c8fbb89e0642478b3eda 186 Pfam PF13023 HD domain 13 171 9.8E-41 T 12-10-2018 IPR006674 HD domain NPD12_1831 7022bc363278c8fbb89e0642478b3eda 186 SUPERFAMILY SSF109604 4 156 4.45E-38 T 12-10-2018 NPD12_1831 7022bc363278c8fbb89e0642478b3eda 186 SMART SM00471 29 144 1.8E-4 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_1831 7022bc363278c8fbb89e0642478b3eda 186 Gene3D G3DSA:1.10.3210.10 2 185 2.4E-45 T 12-10-2018 NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 14 455 3.2E-131 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 SUPERFAMILY SSF56235 14 243 3.09E-61 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 SUPERFAMILY SSF53271 252 456 9.7E-55 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 Gene3D G3DSA:3.40.50.2020 276 440 2.7E-141 T 12-10-2018 NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 13 455 41.937 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 Gene3D G3DSA:3.60.20.10 14 456 2.7E-141 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 Pfam PF13537 Glutamine amidotransferase domain 93 214 4.4E-19 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 PIRSF PIRSF000485 10 457 4.2E-149 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 NPD12_2964 aab1c01c62a985d49889afcd3752a7f3 458 Pfam PF00156 Phosphoribosyl transferase domain 281 389 3.7E-8 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_2993 87b4b522e5c34b7c2617211cef74e984 125 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 121 1.5E-24 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 NPD12_2993 87b4b522e5c34b7c2617211cef74e984 125 SUPERFAMILY SSF57863 6 106 6.02E-18 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger NPD12_2993 87b4b522e5c34b7c2617211cef74e984 125 Pfam PF02565 Recombination protein O C terminal 7 116 2.2E-23 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 NPD12_2993 87b4b522e5c34b7c2617211cef74e984 125 Gene3D G3DSA:1.20.1440.120 1 123 1.2E-5 T 12-10-2018 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 4.3E-86 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 99 1.1E-18 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 Gene3D G3DSA:3.40.50.720 1 163 5.6E-49 T 12-10-2018 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 Gene3D G3DSA:1.10.3730.10 164 268 4.1E-41 T 12-10-2018 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 PIRSF PIRSF000193 2 268 3.1E-84 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 27.542 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 SUPERFAMILY SSF51735 5 160 1.05E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 6.3E-41 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 NPD12_3293 74b26817aab5aa99e194425d1cacc6ad 268 SUPERFAMILY SSF48179 161 268 1.68E-39 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 NPD12_3327 415c58f6959b4530eeb8d5e7667849c7 742 ProSitePatterns PS00850 Glycine radical domain signature. 712 720 - T 12-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site NPD12_3327 415c58f6959b4530eeb8d5e7667849c7 742 PIRSF PIRSF000379 2 742 0.0 T 12-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 NPD12_3327 415c58f6959b4530eeb8d5e7667849c7 742 Pfam PF02901 Pyruvate formate lyase-like 17 600 9.5E-202 T 12-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 NPD12_3327 415c58f6959b4530eeb8d5e7667849c7 742 Pfam PF01228 Glycine radical 616 723 1.2E-42 T 12-10-2018 IPR001150 Glycine radical domain GO:0003824 NPD12_3327 415c58f6959b4530eeb8d5e7667849c7 742 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 6 742 0.0 T 12-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 NPD12_3327 415c58f6959b4530eeb8d5e7667849c7 742 Gene3D G3DSA:3.20.70.20 1 742 1.0E-293 T 12-10-2018 NPD12_3327 415c58f6959b4530eeb8d5e7667849c7 742 SUPERFAMILY SSF51998 2 740 1.28E-274 T 12-10-2018 NPD12_3593 bca1e008ea81bb7c71a71045b08d9b8b 391 Gene3D G3DSA:2.30.40.10 4 390 1.3E-152 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_3593 bca1e008ea81bb7c71a71045b08d9b8b 391 PIRSF PIRSF001238 1 391 1.2E-171 T 12-10-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 NPD12_3593 bca1e008ea81bb7c71a71045b08d9b8b 391 Gene3D G3DSA:3.20.20.140 58 343 1.3E-152 T 12-10-2018 NPD12_3593 bca1e008ea81bb7c71a71045b08d9b8b 391 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 3 390 3.3E-172 T 12-10-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 NPD12_3593 bca1e008ea81bb7c71a71045b08d9b8b 391 Pfam PF01979 Amidohydrolase family 53 375 3.2E-16 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 NPD12_3593 bca1e008ea81bb7c71a71045b08d9b8b 391 SUPERFAMILY SSF51556 57 347 2.7E-71 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_3593 bca1e008ea81bb7c71a71045b08d9b8b 391 SUPERFAMILY SSF51338 1 389 1.38E-18 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2010 869891878f9a24271c009d3478b65c09 248 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 245 24.55 T 12-10-2018 IPR003768 Segregation and condensation protein A NPD12_2010 869891878f9a24271c009d3478b65c09 248 Pfam PF02616 Segregation and condensation protein ScpA 20 242 3.5E-35 T 12-10-2018 IPR003768 Segregation and condensation protein A NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.8E-19 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 PRINTS PR01703 Manganese superoxide dismutase signature 66 79 1.8E-19 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.8E-19 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 PRINTS PR01703 Manganese superoxide dismutase signature 119 127 1.8E-19 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 PRINTS PR01703 Manganese superoxide dismutase signature 157 169 1.8E-19 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 Gene3D G3DSA:2.40.500.20 84 198 1.6E-43 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 159 166 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 SUPERFAMILY SSF54719 82 196 1.44E-42 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 7.8E-28 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 192 3.0E-36 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 Gene3D G3DSA:1.10.287.990 20 83 3.3E-26 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 SUPERFAMILY SSF46609 1 86 1.7E-31 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_2400 c17a5e744d23c3e30a893712c012b225 198 PIRSF PIRSF000349 1 198 1.9E-79 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_1571 ecfae4addc281d647adc6b4c05432a1c 223 SMART SM00646 65 168 2.8E-17 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_1571 ecfae4addc281d647adc6b4c05432a1c 223 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 3 167 3.1E-31 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_1571 ecfae4addc281d647adc6b4c05432a1c 223 SUPERFAMILY SSF53187 3 169 3.14E-42 T 12-10-2018 NPD12_1571 ecfae4addc281d647adc6b4c05432a1c 223 Gene3D G3DSA:3.40.630.40 1 173 5.7E-57 T 12-10-2018 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 Pfam PF00037 4Fe-4S binding domain 191 212 6.3E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 Pfam PF00037 4Fe-4S binding domain 161 183 1.7E-4 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 SUPERFAMILY SSF54862 161 217 2.43E-17 T 12-10-2018 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 139 155 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 Gene3D G3DSA:3.30.70.20 159 213 2.2E-12 T 12-10-2018 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 SUPERFAMILY SSF55124 6 98 1.21E-19 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 Gene3D G3DSA:3.30.70.3340 16 93 6.3E-6 T 12-10-2018 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 SUPERFAMILY SSF56014 91 283 5.76E-37 T 12-10-2018 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 20 82 3.8E-15 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_1928 ec3c196c106a17bdf456a7d9c283e368 284 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 93 283 2.2E-29 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 NPD12_3191 35d148642a1737d5475c31274cb6bb13 184 PIRSF PIRSF021383 1 182 4.4E-54 T 12-10-2018 IPR014197 Sporulation protein YunB NPD12_3191 35d148642a1737d5475c31274cb6bb13 184 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 78 167 8.2E-33 T 12-10-2018 IPR014197 Sporulation protein YunB NPD12_3191 35d148642a1737d5475c31274cb6bb13 184 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 2 170 2.3E-60 T 12-10-2018 IPR014197 Sporulation protein YunB NPD12_76 35fcf3e0f327f9b8928d9d0106ed90d6 311 Pfam PF01551 Peptidase family M23 212 306 4.9E-36 T 12-10-2018 IPR016047 Peptidase M23 NPD12_76 35fcf3e0f327f9b8928d9d0106ed90d6 311 SUPERFAMILY SSF51261 119 310 2.41E-54 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_76 35fcf3e0f327f9b8928d9d0106ed90d6 311 Gene3D G3DSA:2.70.70.10 165 311 6.0E-48 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_2761 711c5b47506373127fc8829ca018e76d 358 SMART SM00116 6 54 7.5 T 12-10-2018 IPR000644 CBS domain NPD12_2761 711c5b47506373127fc8829ca018e76d 358 SMART SM00116 70 118 0.001 T 12-10-2018 IPR000644 CBS domain NPD12_2761 711c5b47506373127fc8829ca018e76d 358 Gene3D G3DSA:3.90.550.10 122 349 2.3E-66 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2761 711c5b47506373127fc8829ca018e76d 358 Pfam PF00571 CBS domain 12 54 1.8E-5 T 12-10-2018 IPR000644 CBS domain NPD12_2761 711c5b47506373127fc8829ca018e76d 358 Pfam PF00571 CBS domain 64 114 1.3E-8 T 12-10-2018 IPR000644 CBS domain NPD12_2761 711c5b47506373127fc8829ca018e76d 358 SUPERFAMILY SSF53448 122 347 2.29E-68 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2761 711c5b47506373127fc8829ca018e76d 358 Gene3D G3DSA:3.10.580.10 3 117 1.8E-22 T 12-10-2018 NPD12_2761 711c5b47506373127fc8829ca018e76d 358 SUPERFAMILY SSF54631 8 114 1.39E-22 T 12-10-2018 NPD12_2761 711c5b47506373127fc8829ca018e76d 358 Pfam PF00483 Nucleotidyl transferase 124 345 3.0E-41 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 200 215 1.1E-8 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 184 200 1.1E-8 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 SUPERFAMILY SSF46785 158 235 3.18E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 SMART SM00100 20 139 1.4E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 SUPERFAMILY SSF51206 15 154 5.5E-37 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 Gene3D G3DSA:1.10.10.10 155 236 9.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 SMART SM00419 178 227 2.4E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 Pfam PF00027 Cyclic nucleotide-binding domain 40 126 2.3E-21 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 Pfam PF13545 Crp-like helix-turn-helix domain 160 233 1.0E-17 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_835 ff4bbea379f9fa9c4c2525c8bd3584a7 236 Gene3D G3DSA:2.60.120.10 7 154 8.4E-38 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1734 7c0a42937cf37276fd79633e52ca2414 223 Gene3D G3DSA:3.40.50.300 2 222 3.1E-55 T 12-10-2018 NPD12_1734 7c0a42937cf37276fd79633e52ca2414 223 Pfam PF00005 ABC transporter 23 159 6.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1734 7c0a42937cf37276fd79633e52ca2414 223 SUPERFAMILY SSF52540 5 220 4.14E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1734 7c0a42937cf37276fd79633e52ca2414 223 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1734 7c0a42937cf37276fd79633e52ca2414 223 SMART SM00382 22 209 2.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_471 ec9b959ce3ad78d67a1a885ecc3200f1 323 SMART SM00342 235 318 1.3E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_471 ec9b959ce3ad78d67a1a885ecc3200f1 323 Gene3D G3DSA:1.10.10.60 215 322 4.7E-27 T 12-10-2018 NPD12_471 ec9b959ce3ad78d67a1a885ecc3200f1 323 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 287 302 1.2E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_471 ec9b959ce3ad78d67a1a885ecc3200f1 323 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 302 318 1.2E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_471 ec9b959ce3ad78d67a1a885ecc3200f1 323 Pfam PF12833 Helix-turn-helix domain 243 319 2.3E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_471 ec9b959ce3ad78d67a1a885ecc3200f1 323 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 272 314 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_471 ec9b959ce3ad78d67a1a885ecc3200f1 323 SUPERFAMILY SSF46689 272 321 8.96E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_999 23a18b6b8c3e7f5728464a581ff2ede4 389 Pfam PF01979 Amidohydrolase family 52 381 7.1E-14 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 NPD12_999 23a18b6b8c3e7f5728464a581ff2ede4 389 Gene3D G3DSA:3.20.20.140 56 345 4.6E-123 T 12-10-2018 NPD12_999 23a18b6b8c3e7f5728464a581ff2ede4 389 SUPERFAMILY SSF51338 2 385 3.17E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_999 23a18b6b8c3e7f5728464a581ff2ede4 389 SUPERFAMILY SSF51556 55 349 3.77E-43 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_999 23a18b6b8c3e7f5728464a581ff2ede4 389 Gene3D G3DSA:2.30.40.10 5 379 4.6E-123 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2134 4f4779f5187e695da52e823e19d61803 477 SUPERFAMILY SSF52540 2 218 2.46E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2134 4f4779f5187e695da52e823e19d61803 477 Gene3D G3DSA:3.40.50.300 246 476 1.2E-62 T 12-10-2018 NPD12_2134 4f4779f5187e695da52e823e19d61803 477 Gene3D G3DSA:3.40.50.300 1 244 1.2E-57 T 12-10-2018 NPD12_2134 4f4779f5187e695da52e823e19d61803 477 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2134 4f4779f5187e695da52e823e19d61803 477 Pfam PF00005 ABC transporter 19 169 2.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2134 4f4779f5187e695da52e823e19d61803 477 SMART SM00382 27 223 2.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2134 4f4779f5187e695da52e823e19d61803 477 SMART SM00382 276 461 8.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2134 4f4779f5187e695da52e823e19d61803 477 SUPERFAMILY SSF52540 236 474 1.67E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2134 4f4779f5187e695da52e823e19d61803 477 Pfam PF00005 ABC transporter 267 412 1.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2178 9e0acde304c7f04da0a2014b3a044f68 286 Pfam PF09861 Domain of unknown function (DUF2088) 2 69 4.0E-26 T 12-10-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 NPD12_2178 9e0acde304c7f04da0a2014b3a044f68 286 Gene3D G3DSA:3.40.50.11440 2 133 1.0E-88 T 12-10-2018 NPD12_2178 9e0acde304c7f04da0a2014b3a044f68 286 Gene3D G3DSA:3.90.226.30 134 274 1.0E-88 T 12-10-2018 NPD12_860 150ab907ba10afc8f7bad5c34acfa3f8 1003 Pfam PF13289 SIR2-like domain 114 269 1.8E-23 T 12-10-2018 IPR039444 SIR2-like domain NPD12_860 150ab907ba10afc8f7bad5c34acfa3f8 1003 SUPERFAMILY SSF52467 19 253 1.68E-13 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 SUPERFAMILY SSF54814 2 107 1.28E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 SUPERFAMILY SSF54821 108 207 4.45E-39 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 Pfam PF07650 KH domain 38 111 1.1E-19 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 Gene3D G3DSA:3.30.300.20 17 108 5.8E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 SMART SM00322 60 126 4.6E-10 T 12-10-2018 IPR004087 K Homology domain GO:0003676 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 Pfam PF00189 Ribosomal protein S3, C-terminal domain 121 203 3.6E-40 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 207 38.523 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.8E-95 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 ProSitePatterns PS00548 Ribosomal protein S3 signature. 164 198 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3633 21ee5ee6a9cda7161206860687a35fa3 223 Gene3D G3DSA:3.30.1140.32 109 209 4.3E-43 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_2293 021944af4742c7cc94958144ede3c31e 204 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 163 1.8E-7 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_2293 021944af4742c7cc94958144ede3c31e 204 SUPERFAMILY SSF51161 2 194 7.9E-53 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_2293 021944af4742c7cc94958144ede3c31e 204 Pfam PF12464 Maltose acetyltransferase 6 57 8.7E-11 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 NPD12_2293 021944af4742c7cc94958144ede3c31e 204 SMART SM01266 4 58 9.2E-14 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 NPD12_2293 021944af4742c7cc94958144ede3c31e 204 Gene3D G3DSA:2.160.10.10 1 201 2.8E-67 T 12-10-2018 NPD12_66 897a6573fa4db3da3264f2cbe2d1313a 144 Pfam PF07977 FabA-like domain 14 137 3.6E-35 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 NPD12_66 897a6573fa4db3da3264f2cbe2d1313a 144 SUPERFAMILY SSF54637 7 142 2.96E-45 T 12-10-2018 IPR029069 HotDog domain superfamily NPD12_66 897a6573fa4db3da3264f2cbe2d1313a 144 Gene3D G3DSA:3.10.129.10 1 144 3.2E-57 T 12-10-2018 NPD12_66 897a6573fa4db3da3264f2cbe2d1313a 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 5 141 1.2E-57 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 NPD12_66 897a6573fa4db3da3264f2cbe2d1313a 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 5 144 33.919 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 NPD12_1633 eb0e974e9d15df6b5169c01d294bb4a1 335 Gene3D G3DSA:3.40.190.10 48 330 4.4E-98 T 12-10-2018 NPD12_1633 eb0e974e9d15df6b5169c01d294bb4a1 335 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 72 208 2.8E-10 T 12-10-2018 NPD12_1633 eb0e974e9d15df6b5169c01d294bb4a1 335 Gene3D G3DSA:3.40.190.10 120 229 4.4E-98 T 12-10-2018 NPD12_1633 eb0e974e9d15df6b5169c01d294bb4a1 335 PIRSF PIRSF027386 1 334 4.5E-127 T 12-10-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type NPD12_1633 eb0e974e9d15df6b5169c01d294bb4a1 335 SUPERFAMILY SSF53850 46 317 4.15E-36 T 12-10-2018 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 SMART SM00387 309 419 8.0E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 Gene3D G3DSA:3.30.565.10 266 418 2.4E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 Gene3D G3DSA:1.10.287.130 192 263 2.7E-14 T 12-10-2018 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 264 7.8E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 SUPERFAMILY SSF47384 186 264 5.49E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 416 8.3E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 1.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 1.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 1.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 1.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 SMART SM00388 198 264 5.0E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_972 7f7e8001e3106e42eee5e1b51ab4676d 420 SUPERFAMILY SSF55874 254 415 3.8E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1278 be04203955d0a7b32bd64937252422d6 318 Pfam PF00005 ABC transporter 17 165 2.2E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1278 be04203955d0a7b32bd64937252422d6 318 SUPERFAMILY SSF55021 236 317 3.09E-15 T 12-10-2018 NPD12_1278 be04203955d0a7b32bd64937252422d6 318 SUPERFAMILY SSF52540 1 233 1.12E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1278 be04203955d0a7b32bd64937252422d6 318 Pfam PF09383 NIL domain 248 317 2.2E-13 T 12-10-2018 IPR018449 NIL domain NPD12_1278 be04203955d0a7b32bd64937252422d6 318 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1278 be04203955d0a7b32bd64937252422d6 318 SMART SM00930 245 318 1.6E-17 T 12-10-2018 IPR018449 NIL domain NPD12_1278 be04203955d0a7b32bd64937252422d6 318 Gene3D G3DSA:3.40.50.300 1 228 1.8E-72 T 12-10-2018 NPD12_1278 be04203955d0a7b32bd64937252422d6 318 Gene3D G3DSA:3.30.70.260 229 318 4.2E-9 T 12-10-2018 NPD12_1278 be04203955d0a7b32bd64937252422d6 318 SMART SM00382 26 214 1.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2357 1a7209ee8bba2e688cbde772aa539f7c 380 PIRSF PIRSF006078 1 378 8.4E-136 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 NPD12_2357 1a7209ee8bba2e688cbde772aa539f7c 380 Gene3D G3DSA:3.40.50.10350 1 363 1.7E-137 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold NPD12_2357 1a7209ee8bba2e688cbde772aa539f7c 380 SUPERFAMILY SSF110738 1 376 1.2E-136 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 NPD12_2357 1a7209ee8bba2e688cbde772aa539f7c 380 Gene3D G3DSA:3.90.1510.10 42 277 1.7E-137 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 NPD12_2357 1a7209ee8bba2e688cbde772aa539f7c 380 Pfam PF02595 Glycerate kinase family 3 374 2.1E-145 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 NPD12_2357 1a7209ee8bba2e688cbde772aa539f7c 380 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 4.3E-156 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 NPD12_3421 9be13764ea8f6baf68d7bb01e54026fa 543 Gene3D G3DSA:3.30.300.30 435 538 2.5E-31 T 12-10-2018 NPD12_3421 9be13764ea8f6baf68d7bb01e54026fa 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 12-10-2018 IPR020845 AMP-binding, conserved site NPD12_3421 9be13764ea8f6baf68d7bb01e54026fa 543 SUPERFAMILY SSF56801 4 534 6.67E-135 T 12-10-2018 NPD12_3421 9be13764ea8f6baf68d7bb01e54026fa 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 523 2.1E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain NPD12_3421 9be13764ea8f6baf68d7bb01e54026fa 543 Gene3D G3DSA:3.40.50.12780 3 434 2.2E-103 T 12-10-2018 NPD12_3421 9be13764ea8f6baf68d7bb01e54026fa 543 Pfam PF00501 AMP-binding enzyme 13 439 3.4E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 NPD12_1946 6dcf004f6144b5b390579af12ce43096 427 SUPERFAMILY SSF53383 48 379 2.55E-40 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1946 6dcf004f6144b5b390579af12ce43096 427 Gene3D G3DSA:3.90.1150.60 28 421 1.0E-182 T 12-10-2018 NPD12_1946 6dcf004f6144b5b390579af12ce43096 427 Gene3D G3DSA:3.40.640.10 66 282 1.0E-182 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1946 6dcf004f6144b5b390579af12ce43096 427 Pfam PF06838 Methionine gamma-lyase 21 425 9.5E-206 T 12-10-2018 IPR009651 Putative methionine gamma-lyase NPD12_2714 0d83b74e84860047e1f411ad6ae5e209 144 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 94 141 3.5E-11 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain NPD12_2714 0d83b74e84860047e1f411ad6ae5e209 144 Pfam PF00460 Flagella basal body rod protein 8 35 3.4E-9 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 NPD12_2714 0d83b74e84860047e1f411ad6ae5e209 144 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 144 1.1E-51 T 12-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 NPD12_420 8a0845e6f68813e4fbfd5d97bec3675a 107 SUPERFAMILY SSF54665 10 75 7.07E-17 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily NPD12_420 8a0845e6f68813e4fbfd5d97bec3675a 107 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 15 55 9.2E-8 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead NPD12_420 8a0845e6f68813e4fbfd5d97bec3675a 107 Gene3D G3DSA:3.90.1170.50 10 55 1.3E-19 T 12-10-2018 NPD12_420 8a0845e6f68813e4fbfd5d97bec3675a 107 Gene3D G3DSA:3.30.365.10 56 99 1.3E-19 T 12-10-2018 NPD12_3067 3186da8501326182ce9a3184b9a71891 184 Gene3D G3DSA:2.40.50.140 1 181 1.1E-70 T 12-10-2018 NPD12_3067 3186da8501326182ce9a3184b9a71891 184 SUPERFAMILY SSF50249 8 174 1.11E-47 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3067 3186da8501326182ce9a3184b9a71891 184 Pfam PF10991 Protein of unknown function (DUF2815) 10 176 1.1E-73 T 12-10-2018 IPR022595 Protein of unknown function DUF2815 NPD12_2645 c11ed41647de12a48eb09bdf0cb3b388 274 Gene3D G3DSA:3.30.1240.10 83 197 1.2E-65 T 12-10-2018 NPD12_2645 c11ed41647de12a48eb09bdf0cb3b388 274 SUPERFAMILY SSF56784 2 273 4.42E-66 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_2645 c11ed41647de12a48eb09bdf0cb3b388 274 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 269 9.1E-60 T 12-10-2018 IPR000150 Cof family GO:0016787 NPD12_2645 c11ed41647de12a48eb09bdf0cb3b388 274 Gene3D G3DSA:3.40.50.1000 6 269 1.2E-65 T 12-10-2018 IPR023214 HAD superfamily NPD12_2645 c11ed41647de12a48eb09bdf0cb3b388 274 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 12-10-2018 NPD12_2645 c11ed41647de12a48eb09bdf0cb3b388 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 241 3.7E-26 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 NPD12_2645 c11ed41647de12a48eb09bdf0cb3b388 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 269 8.4E-62 T 12-10-2018 NPD12_900 8b7c044c2065b0cccfec8436f4878e27 752 SUPERFAMILY SSF52540 201 738 4.67E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_900 8b7c044c2065b0cccfec8436f4878e27 752 Pfam PF13245 AAA domain 212 560 2.6E-12 T 12-10-2018 NPD12_900 8b7c044c2065b0cccfec8436f4878e27 752 Pfam PF13361 UvrD-like helicase C-terminal domain 581 667 5.8E-6 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 NPD12_900 8b7c044c2065b0cccfec8436f4878e27 752 Gene3D G3DSA:3.40.50.300 584 749 4.4E-50 T 12-10-2018 NPD12_900 8b7c044c2065b0cccfec8436f4878e27 752 Pfam PF13538 UvrD-like helicase C-terminal domain 690 732 1.4E-6 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain NPD12_2164 e18a2681fcc64487b6889dbf92993383 354 Gene3D G3DSA:3.30.360.10 126 345 4.9E-121 T 12-10-2018 NPD12_2164 e18a2681fcc64487b6889dbf92993383 354 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 125 4.2E-25 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 NPD12_2164 e18a2681fcc64487b6889dbf92993383 354 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 242 3.2E-13 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 NPD12_2164 e18a2681fcc64487b6889dbf92993383 354 SUPERFAMILY SSF55347 132 285 1.09E-28 T 12-10-2018 NPD12_2164 e18a2681fcc64487b6889dbf92993383 354 Gene3D G3DSA:3.40.50.720 6 322 4.9E-121 T 12-10-2018 NPD12_2164 e18a2681fcc64487b6889dbf92993383 354 SUPERFAMILY SSF51735 3 160 9.08E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2409 b9a1d90f9a2a35a2f6cfc3f5818de407 253 SMART SM00479 2 183 3.4E-10 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_2409 b9a1d90f9a2a35a2f6cfc3f5818de407 253 Gene3D G3DSA:3.30.420.10 1 235 1.3E-39 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_2409 b9a1d90f9a2a35a2f6cfc3f5818de407 253 Pfam PF00929 Exonuclease 4 174 1.6E-14 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_2409 b9a1d90f9a2a35a2f6cfc3f5818de407 253 SUPERFAMILY SSF53098 1 186 6.33E-29 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_168 3a7eca5677d8427a82419353496673a2 113 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 12 106 22.368 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family NPD12_168 3a7eca5677d8427a82419353496673a2 113 PIRSF PIRSF004555 10 113 5.9E-38 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family NPD12_168 3a7eca5677d8427a82419353496673a2 113 Pfam PF02575 YbaB/EbfC DNA-binding family 18 108 5.2E-33 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family NPD12_168 3a7eca5677d8427a82419353496673a2 113 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 13 112 1.9E-27 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family NPD12_168 3a7eca5677d8427a82419353496673a2 113 Gene3D G3DSA:3.30.1310.10 6 113 1.8E-37 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily NPD12_168 3a7eca5677d8427a82419353496673a2 113 SUPERFAMILY SSF82607 18 112 1.83E-30 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily NPD12_1585 cfd939b7ac27e7ff1d6a6b73d698af2d 134 Pfam PF07486 Cell Wall Hydrolase 45 103 3.1E-14 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 NPD12_1585 cfd939b7ac27e7ff1d6a6b73d698af2d 134 Gene3D G3DSA:1.10.10.2520 28 107 1.3E-26 T 12-10-2018 NPD12_1962 459e0d7f7ced35aa4485faf127377b7c 294 Gene3D G3DSA:3.40.50.10490 98 283 2.2E-37 T 12-10-2018 NPD12_1962 459e0d7f7ced35aa4485faf127377b7c 294 SUPERFAMILY SSF46689 7 83 2.69E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1962 459e0d7f7ced35aa4485faf127377b7c 294 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 80 3.7E-14 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_1962 459e0d7f7ced35aa4485faf127377b7c 294 Gene3D G3DSA:1.10.10.10 3 81 2.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1962 459e0d7f7ced35aa4485faf127377b7c 294 SUPERFAMILY SSF53697 103 269 2.22E-29 T 12-10-2018 NPD12_1962 459e0d7f7ced35aa4485faf127377b7c 294 Pfam PF01380 SIS domain 132 258 2.6E-28 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_2838 02a0bd6f752010ede97a3a8bceeee6d6 213 Gene3D G3DSA:3.30.70.20 162 212 5.3E-10 T 12-10-2018 NPD12_2838 02a0bd6f752010ede97a3a8bceeee6d6 213 SUPERFAMILY SSF54862 49 212 1.73E-16 T 12-10-2018 NPD12_2838 02a0bd6f752010ede97a3a8bceeee6d6 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2838 02a0bd6f752010ede97a3a8bceeee6d6 213 Pfam PF13187 4Fe-4S dicluster domain 168 211 6.5E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2838 02a0bd6f752010ede97a3a8bceeee6d6 213 Pfam PF12801 4Fe-4S binding domain 31 66 6.3E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2838 02a0bd6f752010ede97a3a8bceeee6d6 213 Pfam PF12801 4Fe-4S binding domain 121 157 3.1E-4 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_3107 ec9e002848ec73139d6c790a41d21ef1 285 Gene3D G3DSA:2.40.10.350 178 259 1.7E-44 T 12-10-2018 NPD12_3107 ec9e002848ec73139d6c790a41d21ef1 285 PIRSF PIRSF038471 1 283 3.4E-86 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 NPD12_3107 ec9e002848ec73139d6c790a41d21ef1 285 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 278 5.8E-41 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 NPD12_3107 ec9e002848ec73139d6c790a41d21ef1 285 Pfam PF04085 rod shape-determining protein MreC 121 271 7.5E-40 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 NPD12_3107 ec9e002848ec73139d6c790a41d21ef1 285 Gene3D G3DSA:2.40.10.340 119 270 1.7E-44 T 12-10-2018 NPD12_2957 e63a4e096aa1645f31f4f133d455b209 353 Gene3D G3DSA:2.30.30.280 212 271 1.3E-17 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 NPD12_2957 e63a4e096aa1645f31f4f133d455b209 353 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 5 349 6.8E-111 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 NPD12_2957 e63a4e096aa1645f31f4f133d455b209 353 SUPERFAMILY SSF52402 2 241 5.95E-60 T 12-10-2018 NPD12_2957 e63a4e096aa1645f31f4f133d455b209 353 Gene3D G3DSA:3.40.50.620 1 207 4.7E-83 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2957 e63a4e096aa1645f31f4f133d455b209 353 Gene3D G3DSA:2.40.30.10 272 352 2.5E-25 T 12-10-2018 NPD12_2957 e63a4e096aa1645f31f4f133d455b209 353 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 350 40.018 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 NPD12_2957 e63a4e096aa1645f31f4f133d455b209 353 Pfam PF03054 tRNA methyl transferase 5 349 1.4E-121 T 12-10-2018 NPD12_274 0762731f2e15d704e18901ed56461165 873 Gene3D G3DSA:3.30.470.20 206 362 2.1E-14 T 12-10-2018 NPD12_274 0762731f2e15d704e18901ed56461165 873 Pfam PF02875 Mur ligase family, glutamate ligase domain 717 791 2.0E-10 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 NPD12_274 0762731f2e15d704e18901ed56461165 873 Gene3D G3DSA:3.90.190.20 721 869 9.3E-24 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_274 0762731f2e15d704e18901ed56461165 873 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 859 0.0 T 12-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 NPD12_274 0762731f2e15d704e18901ed56461165 873 Gene3D G3DSA:3.30.1490.20 228 294 2.1E-14 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 NPD12_274 0762731f2e15d704e18901ed56461165 873 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 480 504 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 NPD12_274 0762731f2e15d704e18901ed56461165 873 Pfam PF08443 RimK-like ATP-grasp domain 212 315 1.1E-7 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 NPD12_274 0762731f2e15d704e18901ed56461165 873 Pfam PF08443 RimK-like ATP-grasp domain 384 466 6.2E-5 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 NPD12_274 0762731f2e15d704e18901ed56461165 873 SUPERFAMILY SSF53623 441 728 9.68E-48 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_274 0762731f2e15d704e18901ed56461165 873 SUPERFAMILY SSF56059 213 474 4.55E-31 T 12-10-2018 NPD12_274 0762731f2e15d704e18901ed56461165 873 Pfam PF08245 Mur ligase middle domain 482 692 7.1E-34 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 NPD12_274 0762731f2e15d704e18901ed56461165 873 Gene3D G3DSA:3.40.1190.10 471 713 8.7E-43 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_274 0762731f2e15d704e18901ed56461165 873 Gene3D G3DSA:3.30.470.20 373 470 1.7E-13 T 12-10-2018 NPD12_274 0762731f2e15d704e18901ed56461165 873 SUPERFAMILY SSF53244 717 845 2.56E-25 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_1668 ed57e289ea977488258a20ee9b7ac27c 72 Pfam PF12844 Helix-turn-helix domain 4 61 6.4E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1668 ed57e289ea977488258a20ee9b7ac27c 72 SUPERFAMILY SSF47413 3 70 4.15E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1668 ed57e289ea977488258a20ee9b7ac27c 72 Gene3D G3DSA:1.10.260.40 2 72 1.8E-11 T 12-10-2018 NPD12_1686 cd0a22da77f040aff89de20b6f0b3e0d 501 Pfam PF01943 Polysaccharide biosynthesis protein 10 308 6.0E-15 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 NPD12_1686 cd0a22da77f040aff89de20b6f0b3e0d 501 PIRSF PIRSF038958 3 499 3.7E-69 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type NPD12_1686 cd0a22da77f040aff89de20b6f0b3e0d 501 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 8 493 3.5E-187 T 12-10-2018 IPR014249 Sporulation stage V protein B NPD12_1686 cd0a22da77f040aff89de20b6f0b3e0d 501 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 359 494 1.1E-11 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 378 2.7E-28 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 461 35.449 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 461 3.4E-129 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 Gene3D G3DSA:3.30.1360.120 1 127 6.0E-47 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 SUPERFAMILY SSF52540 81 378 1.52E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 Gene3D G3DSA:1.20.120.430 128 461 4.7E-110 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 127 1.7E-40 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 Pfam PF01926 50S ribosome-binding GTPase 226 338 2.2E-28 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 SUPERFAMILY SSF116878 128 461 4.84E-49 T 12-10-2018 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 Pfam PF12631 MnmE helical domain 130 458 6.0E-60 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 NPD12_122 1217a2248b0c427aac1c07e5df18549b 461 Gene3D G3DSA:3.40.50.300 224 389 4.7E-110 T 12-10-2018 NPD12_1656 7f0cf886ae691b5caf1447bbf5ad7acf 629 Pfam PF02687 FtsX-like permease family 85 180 1.3E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_1656 7f0cf886ae691b5caf1447bbf5ad7acf 629 PIRSF PIRSF018968 1 629 6.7E-119 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 Gene3D G3DSA:3.40.50.300 1032 1192 2.2E-49 T 12-10-2018 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1176 5.3E-49 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 Gene3D G3DSA:3.40.50.300 1 255 5.7E-60 T 12-10-2018 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 SUPERFAMILY SSF57997 293 489 2.55E-7 T 12-10-2018 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 Gene3D G3DSA:1.20.1060.20 499 685 8.4E-65 T 12-10-2018 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 SUPERFAMILY SSF75553 486 693 4.58E-52 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 SMART SM00968 526 642 2.0E-37 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1183 0.0 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 Pfam PF06470 SMC proteins Flexible Hinge Domain 530 642 8.5E-28 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 PIRSF PIRSF005719 1 1191 4.4E-302 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 SUPERFAMILY SSF52540 1 1169 1.15E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1185 22.947 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 NPD12_2500 26757a9c1eef7598e4a02502789e01f0 1193 Gene3D G3DSA:3.30.70.1620 586 671 8.4E-65 T 12-10-2018 NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 SUPERFAMILY SSF55136 120 272 3.66E-20 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 Pfam PF06445 GyrI-like small molecule binding domain 120 270 2.3E-16 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 Gene3D G3DSA:3.20.80.10 114 272 8.9E-22 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 Pfam PF13411 MerR HTH family regulatory protein 3 71 2.9E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 Gene3D G3DSA:1.10.1660.10 2 110 3.5E-23 T 12-10-2018 NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 SMART SM00422 2 72 4.4E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 SUPERFAMILY SSF46955 2 106 3.37E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_2369 a87f5dd41024afe9d67cebbbb257e972 272 SMART SM00871 119 270 1.4E-28 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 Pfam PF04539 Sigma-70 region 3 94 172 2.6E-9 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 Pfam PF04542 Sigma-70 region 2 15 85 1.9E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 SUPERFAMILY SSF88659 150 238 7.48E-24 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 PRINTS PR00046 Major sigma-70 factor signature 41 54 3.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 PRINTS PR00046 Major sigma-70 factor signature 206 221 3.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 PRINTS PR00046 Major sigma-70 factor signature 65 73 3.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 PRINTS PR00046 Major sigma-70 factor signature 189 201 3.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 PRINTS PR00046 Major sigma-70 factor signature 221 232 3.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 SUPERFAMILY SSF88659 88 163 1.22E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 SUPERFAMILY SSF88946 4 85 1.73E-25 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 Gene3D G3DSA:1.10.1740.10 3 83 2.6E-29 T 12-10-2018 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 PIRSF PIRSF000770 5 241 4.8E-39 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 Pfam PF04545 Sigma-70, region 4 185 234 4.0E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 236 2.0E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 14 236 2.5E-80 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 41 54 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2691 96fc76ac2df3a8e1662ae859a9e5633f 242 Gene3D G3DSA:1.20.140.160 87 239 2.9E-39 T 12-10-2018 NPD12_2562 2c06f8d2efcb3af01e56550d9ec2c52c 91 Pfam PF04025 Domain of unknown function (DUF370) 5 77 1.3E-37 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A NPD12_2562 2c06f8d2efcb3af01e56550d9ec2c52c 91 Hamap MF_01503 UPF0296 protein . 3 91 29.98 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A NPD12_2562 2c06f8d2efcb3af01e56550d9ec2c52c 91 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 9.0E-36 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A NPD12_3653 e1e21063e9a4f2a7f00b0916d1e078af 75 Hamap MF_00422 Protein translocase subunit SecE [secE]. 16 71 12.316 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_3653 e1e21063e9a4f2a7f00b0916d1e078af 75 Gene3D G3DSA:1.20.5.1030 16 72 2.1E-16 T 12-10-2018 IPR038379 SecE superfamily NPD12_3653 e1e21063e9a4f2a7f00b0916d1e078af 75 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 20 74 4.1E-17 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 NPD12_3653 e1e21063e9a4f2a7f00b0916d1e078af 75 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 20 72 4.4E-13 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 ProSitePatterns PS00761 Signal peptidases I signature 3. 126 139 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 9 164 1.4E-52 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 SUPERFAMILY SSF51306 24 169 1.57E-52 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 Pfam PF00717 Peptidase S24-like 32 101 7.0E-19 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 Gene3D G3DSA:2.10.109.10 33 162 6.3E-35 T 12-10-2018 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 ProSitePatterns PS00501 Signal peptidases I serine active site. 34 41 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 25 41 3.7E-21 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 3.7E-21 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_2491 d5cf1d102b44e6e606475e931384a838 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 121 140 3.7E-21 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 SMART SM00382 28 247 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 SMART SM00382 357 522 2.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 Pfam PF00005 ABC transporter 349 478 2.0E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 Gene3D G3DSA:3.40.50.300 1 289 3.6E-66 T 12-10-2018 NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 Pfam PF12848 ABC transporter 234 313 1.4E-21 T 12-10-2018 IPR032781 ABC-transporter extension domain NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 SUPERFAMILY SSF52540 314 537 3.26E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 Gene3D G3DSA:3.40.50.300 295 557 2.0E-56 T 12-10-2018 NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 SUPERFAMILY SSF52540 4 247 3.97E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3435 6c028a678b36856619ecabc8c12846b3 640 Pfam PF00005 ABC transporter 19 195 1.9E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3359 5e97b5390a323b6f053b8379f302ba12 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 209 1.8E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_3359 5e97b5390a323b6f053b8379f302ba12 213 Gene3D G3DSA:1.10.3720.10 70 213 5.1E-23 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3359 5e97b5390a323b6f053b8379f302ba12 213 SUPERFAMILY SSF161098 72 210 1.83E-27 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3087 38d38542261d4c12472b85bd51908837 126 Pfam PF01042 Endoribonuclease L-PSP 8 125 8.1E-47 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 NPD12_3087 38d38542261d4c12472b85bd51908837 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 125 5.9E-55 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 NPD12_3087 38d38542261d4c12472b85bd51908837 126 SUPERFAMILY SSF55298 1 126 7.23E-48 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 NPD12_3087 38d38542261d4c12472b85bd51908837 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 NPD12_3087 38d38542261d4c12472b85bd51908837 126 Gene3D G3DSA:3.30.1330.40 1 126 3.8E-55 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 PIRSF PIRSF000098 1 404 1.8E-122 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 Gene3D G3DSA:3.30.70.260 333 396 1.7E-119 T 12-10-2018 NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 122 1.1E-18 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 SUPERFAMILY SSF51735 1 151 6.3E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 Gene3D G3DSA:3.30.360.10 129 332 1.7E-119 T 12-10-2018 NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 Gene3D G3DSA:3.40.50.720 2 327 1.7E-119 T 12-10-2018 NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 SUPERFAMILY SSF55347 130 295 2.22E-43 T 12-10-2018 NPD12_2041 1beecba94fae8ec552a4c11bbbb3534f 408 Pfam PF00742 Homoserine dehydrogenase 130 308 3.8E-56 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 Gene3D G3DSA:3.30.1360.30 281 424 1.3E-194 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 Gene3D G3DSA:3.30.930.10 125 587 1.3E-194 T 12-10-2018 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 SUPERFAMILY SSF50249 8 116 8.0E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 Pfam PF02938 GAD domain 317 409 7.6E-27 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 301 413 0.006 T 12-10-2018 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 216 229 3.3E-25 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 199 211 3.3E-25 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 523 537 3.3E-25 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 479 495 3.3E-25 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 9 589 1.1E-236 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 Pfam PF01336 OB-fold nucleic acid binding domain 26 109 3.3E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 SUPERFAMILY SSF55681 117 589 1.69E-102 T 12-10-2018 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 Gene3D G3DSA:2.40.50.140 6 113 1.8E-29 T 12-10-2018 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 SUPERFAMILY SSF55261 298 424 1.96E-45 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 Pfam PF00152 tRNA synthetases class II (D, K and N) 126 563 2.5E-108 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3163 f51dacbd7d749a20f723812836bed60d 593 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 9 589 33.297 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 NPD12_1548 62e8abe9173c7eb8661efbd45189f98b 364 SUPERFAMILY SSF51445 56 346 1.92E-19 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1548 62e8abe9173c7eb8661efbd45189f98b 364 Gene3D G3DSA:3.20.20.80 44 364 2.0E-59 T 12-10-2018 NPD12_330 7e25f9521dccce2cf25606fb992dd753 175 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 1.8E-27 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 NPD12_330 7e25f9521dccce2cf25606fb992dd753 175 Gene3D G3DSA:3.30.160.100 1 95 6.7E-32 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like NPD12_330 7e25f9521dccce2cf25606fb992dd753 175 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 115 170 6.4E-31 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal NPD12_330 7e25f9521dccce2cf25606fb992dd753 175 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 1.2E-28 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 NPD12_330 7e25f9521dccce2cf25606fb992dd753 175 Gene3D G3DSA:3.30.505.50 128 174 1.2E-27 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily NPD12_330 7e25f9521dccce2cf25606fb992dd753 175 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 174 24.639 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid NPD12_330 7e25f9521dccce2cf25606fb992dd753 175 SUPERFAMILY SSF69754 2 108 3.92E-32 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like NPD12_1129 7f5a5babc21f8c3aabd07bcca6b97154 113 Gene3D G3DSA:3.30.1390.10 72 113 1.3E-6 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like NPD12_48 c792e74061b65e453a27902bf53d5c25 278 Pfam PF04055 Radical SAM superfamily 24 216 1.1E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_48 c792e74061b65e453a27902bf53d5c25 278 Gene3D G3DSA:3.20.20.70 72 276 2.7E-45 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_48 c792e74061b65e453a27902bf53d5c25 278 Gene3D G3DSA:3.20.20.70 2 53 2.1E-14 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_48 c792e74061b65e453a27902bf53d5c25 278 SUPERFAMILY SSF54862 43 94 2.25E-12 T 12-10-2018 NPD12_48 c792e74061b65e453a27902bf53d5c25 278 SUPERFAMILY SSF102114 26 263 8.24E-18 T 12-10-2018 NPD12_48 c792e74061b65e453a27902bf53d5c25 278 Pfam PF13353 4Fe-4S single cluster domain 15 181 5.0E-12 T 12-10-2018 NPD12_48 c792e74061b65e453a27902bf53d5c25 278 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 12-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 NPD12_48 c792e74061b65e453a27902bf53d5c25 278 TIGRFAM TIGR04041 activase_YjjW: glycine radical enzyme activase, YjjW family 4 277 2.4E-119 T 12-10-2018 IPR023912 Putative glycyl-radical enzyme activating enzyme YjjW NPD12_48 c792e74061b65e453a27902bf53d5c25 278 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_48 c792e74061b65e453a27902bf53d5c25 278 PIRSF PIRSF000371 1 277 6.3E-74 T 12-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 NPD12_684 75324267bf82cb7a64d970fcf6a4cb29 137 ProSitePatterns PS00550 Hemerythrin family signature. 59 82 - T 12-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 NPD12_684 75324267bf82cb7a64d970fcf6a4cb29 137 SUPERFAMILY SSF47188 1 131 1.18E-31 T 12-10-2018 IPR035938 Hemerythrin-like superfamily NPD12_684 75324267bf82cb7a64d970fcf6a4cb29 137 Gene3D G3DSA:1.20.120.50 1 136 6.0E-38 T 12-10-2018 IPR035938 Hemerythrin-like superfamily NPD12_684 75324267bf82cb7a64d970fcf6a4cb29 137 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 3 131 2.1E-35 T 12-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 NPD12_684 75324267bf82cb7a64d970fcf6a4cb29 137 Pfam PF01814 Hemerythrin HHE cation binding domain 12 127 4.6E-12 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 Pfam PF00271 Helicase conserved C-terminal domain 231 339 4.0E-33 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 SUPERFAMILY SSF52540 73 361 1.8E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 Pfam PF00270 DEAD/DEAH box helicase 29 196 1.3E-53 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 Pfam PF03880 DbpA RNA binding domain 448 519 7.1E-20 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 SMART SM00490 259 340 1.5E-33 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 Gene3D G3DSA:3.30.70.330 447 522 4.3E-14 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 Gene3D G3DSA:3.40.50.300 1 211 1.5E-76 T 12-10-2018 NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 4 523 42.571 T 12-10-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 SMART SM00487 23 223 6.9E-61 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_2833 872b0b32cc6ee9fb0418ef19c44baaf6 524 Gene3D G3DSA:3.40.50.300 215 446 1.7E-58 T 12-10-2018 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 437 8.9E-149 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 Pfam PF01235 Sodium:alanine symporter family 52 441 9.1E-141 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 89 104 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 PRINTS PR00175 Sodium/alanine symporter signature 347 369 1.1E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 PRINTS PR00175 Sodium/alanine symporter signature 180 198 1.1E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 PRINTS PR00175 Sodium/alanine symporter signature 208 227 1.1E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 PRINTS PR00175 Sodium/alanine symporter signature 303 321 1.1E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 PRINTS PR00175 Sodium/alanine symporter signature 406 426 1.1E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2622 ed3874e731e62c323aa7a7ad82bdccb2 455 PRINTS PR00175 Sodium/alanine symporter signature 89 111 1.1E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 SUPERFAMILY SSF52540 173 436 4.51E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 644 1.2E-215 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 Gene3D G3DSA:3.40.50.300 239 439 1.5E-84 T 12-10-2018 NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 SMART SM00490 487 572 8.6E-24 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 Pfam PF17191 RecG wedge domain 7 169 1.6E-20 T 12-10-2018 IPR033454 RecG, wedge domain NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 Gene3D G3DSA:3.40.50.300 440 612 2.8E-58 T 12-10-2018 NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 SUPERFAMILY SSF52540 369 629 8.91E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 Gene3D G3DSA:2.40.50.140 49 137 1.1E-15 T 12-10-2018 NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 SUPERFAMILY SSF50249 2 169 3.94E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 Pfam PF00270 DEAD/DEAH box helicase 258 414 6.2E-20 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 Pfam PF00271 Helicase conserved C-terminal domain 454 571 1.1E-19 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_2543 5e21945b4647df45e843da441c6d1ff4 679 SMART SM00487 252 442 2.5E-36 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 Gene3D G3DSA:3.60.150.10 1 374 5.3E-133 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 SUPERFAMILY SSF103263 1 371 9.16E-120 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 Pfam PF01264 Chorismate synthase 2 356 2.5E-106 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 Hamap MF_00300 Chorismate synthase [aroC]. 2 363 31.361 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 PIRSF PIRSF001456 1 373 5.8E-119 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 TIGRFAM TIGR00033 aroC: chorismate synthase 2 357 9.9E-108 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3120 82222ef6b2f9f218a22140821f934fc5 374 ProSitePatterns PS00788 Chorismate synthase signature 2. 125 141 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 NPD12_3798 c68340cf566e196a628809d7de4f0623 263 Gene3D G3DSA:3.40.50.12090 185 263 9.4E-24 T 12-10-2018 NPD12_3798 c68340cf566e196a628809d7de4f0623 263 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 6 169 3.3E-32 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3798 c68340cf566e196a628809d7de4f0623 263 Gene3D G3DSA:3.40.630.40 3 172 1.0E-55 T 12-10-2018 NPD12_3798 c68340cf566e196a628809d7de4f0623 263 SUPERFAMILY SSF53187 3 170 2.39E-43 T 12-10-2018 NPD12_3798 c68340cf566e196a628809d7de4f0623 263 SMART SM00646 66 169 4.1E-20 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_335 806b578b40b03b945be93299b25cfb16 197 PIRSF PIRSF037778 2 197 6.7E-52 T 12-10-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 NPD12_335 806b578b40b03b945be93299b25cfb16 197 Pfam PF12822 ECF transporter, substrate-specific component 7 186 7.1E-31 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 NPD12_335 806b578b40b03b945be93299b25cfb16 197 Gene3D G3DSA:1.10.1760.20 3 197 1.4E-57 T 12-10-2018 NPD12_212 1ee56f5ce4bb5f71e261a6a799a080c9 231 SUPERFAMILY SSF52540 1 228 1.87E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_212 1ee56f5ce4bb5f71e261a6a799a080c9 231 Pfam PF02223 Thymidylate kinase 9 190 8.5E-17 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 NPD12_212 1ee56f5ce4bb5f71e261a6a799a080c9 231 Gene3D G3DSA:3.40.50.300 6 220 7.8E-47 T 12-10-2018 NPD12_1811 e031778c909ddfb630673c15f260df34 354 SUPERFAMILY SSF53383 5 350 1.58E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1811 e031778c909ddfb630673c15f260df34 354 Gene3D G3DSA:3.90.1150.10 21 341 1.1E-105 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1811 e031778c909ddfb630673c15f260df34 354 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 207 216 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 NPD12_1811 e031778c909ddfb630673c15f260df34 354 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 350 1.6E-96 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 NPD12_1811 e031778c909ddfb630673c15f260df34 354 Pfam PF00155 Aminotransferase class I and II 25 347 1.0E-54 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1811 e031778c909ddfb630673c15f260df34 354 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 351 56.182 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 NPD12_1811 e031778c909ddfb630673c15f260df34 354 Gene3D G3DSA:3.40.640.10 38 259 1.1E-105 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_3001 dac6500a9300514187ebfdc31df65b25 148 Gene3D G3DSA:1.10.10.410 91 147 1.6E-20 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal NPD12_3001 dac6500a9300514187ebfdc31df65b25 148 Gene3D G3DSA:1.10.1510.10 1 90 1.9E-25 T 12-10-2018 NPD12_3001 dac6500a9300514187ebfdc31df65b25 148 Pfam PF09424 Yqey-like protein 4 146 2.8E-49 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 NPD12_3001 dac6500a9300514187ebfdc31df65b25 148 SUPERFAMILY SSF89095 1 146 1.41E-38 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 NPD12_195 7401712182b9d1fda28d47863aa8ffad 93 Pfam PF04914 DltD protein 2 80 1.2E-5 T 12-10-2018 IPR006998 DltD NPD12_262 7449bd5704759e58b7425076c92c8dfd 424 Gene3D G3DSA:3.40.190.10 147 403 4.9E-47 T 12-10-2018 NPD12_262 7449bd5704759e58b7425076c92c8dfd 424 SUPERFAMILY SSF53850 36 420 2.45E-39 T 12-10-2018 NPD12_262 7449bd5704759e58b7425076c92c8dfd 424 Gene3D G3DSA:3.40.190.10 54 353 4.9E-47 T 12-10-2018 NPD12_262 7449bd5704759e58b7425076c92c8dfd 424 Pfam PF13416 Bacterial extracellular solute-binding protein 54 347 7.1E-20 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein NPD12_1759 fef76fd2a968a6f4508dc96431512d4f 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 292 3.3E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1759 fef76fd2a968a6f4508dc96431512d4f 297 SUPERFAMILY SSF161098 56 284 7.19E-61 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1759 fef76fd2a968a6f4508dc96431512d4f 297 Gene3D G3DSA:1.10.3720.10 54 295 7.9E-74 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1003 2e81790c606c5f713c1a8b602511197d 260 SUPERFAMILY SSF52540 28 202 9.3E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1003 2e81790c606c5f713c1a8b602511197d 260 Gene3D G3DSA:3.40.50.300 28 217 4.8E-43 T 12-10-2018 NPD12_1003 2e81790c606c5f713c1a8b602511197d 260 Pfam PF02421 Ferrous iron transport protein B 28 181 3.2E-62 T 12-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 SUPERFAMILY SSF46689 4 55 7.17E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 Pfam PF06445 GyrI-like small molecule binding domain 128 279 2.8E-22 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 Gene3D G3DSA:3.20.80.10 128 284 2.8E-40 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 SUPERFAMILY SSF46689 57 110 1.48E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 Gene3D G3DSA:1.10.10.60 2 54 7.0E-15 T 12-10-2018 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 SMART SM00342 21 104 1.2E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 Pfam PF12833 Helix-turn-helix domain 29 103 4.3E-15 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 Gene3D G3DSA:1.10.10.60 55 106 4.5E-12 T 12-10-2018 NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 SUPERFAMILY SSF55136 128 282 4.71E-24 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_903 658987ae4bcfb7d400cfe247a97fd140 284 SMART SM00871 128 280 1.1E-27 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Gene3D G3DSA:3.30.310.50 371 449 3.4E-25 T 12-10-2018 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 4.8E-44 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 3.6E-173 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 368 1.1E-34 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 445 9.1E-15 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Gene3D G3DSA:3.40.120.10 3 154 3.6E-53 T 12-10-2018 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 254 1.1E-16 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Gene3D G3DSA:3.40.120.10 174 363 4.2E-70 T 12-10-2018 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 SUPERFAMILY SSF53738 258 365 1.06E-31 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 447 44.12 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 SUPERFAMILY SSF55957 358 448 1.2E-20 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 SUPERFAMILY SSF53738 3 181 7.06E-47 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 SUPERFAMILY SSF53738 158 257 3.81E-28 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 NPD12_3578 6fbd173a8fbac94fea52e1e7660578f3 449 Gene3D G3DSA:3.40.120.10 257 340 4.2E-70 T 12-10-2018 NPD12_526 f988576f5ed5e07359579bcc53f1db19 440 Gene3D G3DSA:3.40.640.10 49 307 1.8E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_526 f988576f5ed5e07359579bcc53f1db19 440 Pfam PF00266 Aminotransferase class-V 31 420 1.3E-84 T 12-10-2018 IPR000192 Aminotransferase class V domain NPD12_526 f988576f5ed5e07359579bcc53f1db19 440 Gene3D G3DSA:3.90.1150.10 24 422 1.8E-107 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_526 f988576f5ed5e07359579bcc53f1db19 440 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 223 242 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site NPD12_526 f988576f5ed5e07359579bcc53f1db19 440 SUPERFAMILY SSF53383 26 430 3.93E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2502 b7d215623d10c33062768c2ed4935668 363 Pfam PF04055 Radical SAM superfamily 12 174 8.9E-23 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2502 b7d215623d10c33062768c2ed4935668 363 Gene3D G3DSA:3.80.30.20 9 255 5.1E-29 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_2502 b7d215623d10c33062768c2ed4935668 363 Pfam PF13394 4Fe-4S single cluster domain 10 101 3.6E-6 T 12-10-2018 NPD12_2502 b7d215623d10c33062768c2ed4935668 363 SMART SM00729 7 226 5.3E-42 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_2502 b7d215623d10c33062768c2ed4935668 363 SUPERFAMILY SSF102114 11 271 2.35E-56 T 12-10-2018 NPD12_2502 b7d215623d10c33062768c2ed4935668 363 Pfam PF16199 Radical_SAM C-terminal domain 187 272 1.0E-20 T 12-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 Pfam PF00753 Metallo-beta-lactamase superfamily 34 168 7.8E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 PIRSF PIRSF005243 1 396 1.3E-152 T 12-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 SUPERFAMILY SSF52218 249 394 2.44E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 SUPERFAMILY SSF56281 9 282 3.52E-58 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 Pfam PF00258 Flavodoxin 254 369 5.0E-9 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 Gene3D G3DSA:3.60.15.10 1 245 7.3E-102 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 Gene3D G3DSA:3.40.50.360 251 396 4.2E-36 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1321 ba23958ad42a009b849ec7a0248a79be 396 SMART SM00849 34 225 1.1E-30 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_3784 fbdddd151ea1cb0831d0a6140d5f40dd 210 Pfam PF09851 Short C-terminal domain 180 207 1.2E-6 T 12-10-2018 IPR018649 SHOCT domain NPD12_124 2c5679686e3e7bce3b15da26d977518e 217 Pfam PF02096 60Kd inner membrane protein 30 208 8.4E-62 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 NPD12_124 2c5679686e3e7bce3b15da26d977518e 217 PRINTS PR00701 60kDa inner membrane protein signature 174 197 2.6E-14 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 NPD12_124 2c5679686e3e7bce3b15da26d977518e 217 PRINTS PR00701 60kDa inner membrane protein signature 91 114 2.6E-14 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 NPD12_124 2c5679686e3e7bce3b15da26d977518e 217 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 29 208 3.1E-64 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_814 904b9bb9d0eff34c8083e83775544908 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 1.6E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_814 904b9bb9d0eff34c8083e83775544908 469 Gene3D G3DSA:1.10.10.10 2 85 1.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_814 904b9bb9d0eff34c8083e83775544908 469 SUPERFAMILY SSF46785 4 83 1.36E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_814 904b9bb9d0eff34c8083e83775544908 469 Gene3D G3DSA:3.40.640.10 99 460 1.9E-119 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_814 904b9bb9d0eff34c8083e83775544908 469 SUPERFAMILY SSF53383 89 466 5.46E-84 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_814 904b9bb9d0eff34c8083e83775544908 469 Pfam PF00155 Aminotransferase class I and II 140 433 5.4E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_814 904b9bb9d0eff34c8083e83775544908 469 SMART SM00345 16 75 1.0E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 Pfam PF00550 Phosphopantetheine attachment site 543 607 2.4E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 PRINTS PR00154 AMP-binding signature 191 199 8.9E-5 T 12-10-2018 IPR020459 AMP-binding NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 PRINTS PR00154 AMP-binding signature 179 190 8.9E-5 T 12-10-2018 IPR020459 AMP-binding NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 Gene3D G3DSA:3.30.300.30 424 526 1.0E-15 T 12-10-2018 NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 Pfam PF00501 AMP-binding enzyme 44 429 1.6E-58 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 12-10-2018 IPR020845 AMP-binding, conserved site NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 SUPERFAMILY SSF47336 538 607 1.83E-12 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 Gene3D G3DSA:3.40.50.12780 32 421 3.4E-74 T 12-10-2018 NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 Gene3D G3DSA:1.10.1200.10 537 607 4.9E-10 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2633 880be2ef5ced3cc2abb6ca9d130f4ca5 609 SUPERFAMILY SSF56801 30 521 4.71E-89 T 12-10-2018 NPD12_2252 c9338627180963c8f987452ededfde7d 846 Hamap MF_02058 Choline trimethylamine-lyase [cutC]. 54 846 57.715 T 12-10-2018 IPR030897 Choline trimethylamine-lyase GO:0016829 MetaCyc: PWY-7167 NPD12_2252 c9338627180963c8f987452ededfde7d 846 TIGRFAM TIGR04394 choline_CutC: choline trimethylamine-lyase 58 846 0.0 T 12-10-2018 IPR030897 Choline trimethylamine-lyase GO:0016829 MetaCyc: PWY-7167 NPD12_2252 c9338627180963c8f987452ededfde7d 846 SUPERFAMILY SSF51998 58 843 6.1E-235 T 12-10-2018 NPD12_2252 c9338627180963c8f987452ededfde7d 846 ProSitePatterns PS00850 Glycine radical domain signature. 816 824 - T 12-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site NPD12_2252 c9338627180963c8f987452ededfde7d 846 Pfam PF02901 Pyruvate formate lyase-like 58 707 3.3E-232 T 12-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 NPD12_2252 c9338627180963c8f987452ededfde7d 846 Gene3D G3DSA:3.20.70.40 44 846 0.0 T 12-10-2018 NPD12_2252 c9338627180963c8f987452ededfde7d 846 Pfam PF01228 Glycine radical 724 827 9.0E-26 T 12-10-2018 IPR001150 Glycine radical domain GO:0003824 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 Gene3D G3DSA:3.30.70.1560 130 214 1.5E-56 T 12-10-2018 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 SMART SM00363 2 62 6.2E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 Gene3D G3DSA:3.30.70.580 63 232 1.5E-56 T 12-10-2018 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 Pfam PF00849 RNA pseudouridylate synthase 63 196 1.8E-19 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 SUPERFAMILY SSF55174 3 59 4.71E-12 T 12-10-2018 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 Gene3D G3DSA:3.10.290.10 2 59 1.2E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 Pfam PF01479 S4 domain 2 45 4.6E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 SUPERFAMILY SSF55120 48 237 5.22E-43 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_3402 3164d75b5f271614a21fca4497d47956 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 229 2.6E-47 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 Gene3D G3DSA:3.40.50.300 1 215 3.4E-87 T 12-10-2018 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 Pfam PF00406 Adenylate kinase 5 190 4.3E-58 T 12-10-2018 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 PRINTS PR00094 Adenylate kinase signature 160 175 1.9E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 PRINTS PR00094 Adenylate kinase signature 32 46 1.9E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 PRINTS PR00094 Adenylate kinase signature 177 191 1.9E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 PRINTS PR00094 Adenylate kinase signature 4 17 1.9E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 PRINTS PR00094 Adenylate kinase signature 81 97 1.9E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 SUPERFAMILY SSF52540 1 213 6.2E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.4E-83 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.692 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.1E-17 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 NPD12_3618 2384791fa7981f24c69557dccc9d54e8 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 NPD12_2050 64c0d0cfa94670844731055f88f61ffa 71 PIRSF PIRSF006488 1 71 1.0E-22 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 NPD12_2050 64c0d0cfa94670844731055f88f61ffa 71 Gene3D G3DSA:1.10.287.1040 2 71 1.4E-20 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 NPD12_2050 64c0d0cfa94670844731055f88f61ffa 71 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 7 67 14.386 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 NPD12_2050 64c0d0cfa94670844731055f88f61ffa 71 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 4 42 3.0E-6 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 NPD12_2050 64c0d0cfa94670844731055f88f61ffa 71 Pfam PF02609 Exonuclease VII small subunit 8 59 8.0E-19 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 NPD12_2050 64c0d0cfa94670844731055f88f61ffa 71 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 7 61 1.1E-21 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 NPD12_2050 64c0d0cfa94670844731055f88f61ffa 71 SUPERFAMILY SSF116842 2 68 1.2E-19 T 12-10-2018 NPD12_437 7238200908f00bc4c9286e04256c069b 255 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 73 5.8E-20 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_437 7238200908f00bc4c9286e04256c069b 255 Gene3D G3DSA:1.10.10.10 5 74 1.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_437 7238200908f00bc4c9286e04256c069b 255 Pfam PF01380 SIS domain 118 216 3.2E-13 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_437 7238200908f00bc4c9286e04256c069b 255 SUPERFAMILY SSF46689 8 73 7.7E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_437 7238200908f00bc4c9286e04256c069b 255 Gene3D G3DSA:3.40.50.10490 87 254 2.2E-30 T 12-10-2018 NPD12_437 7238200908f00bc4c9286e04256c069b 255 SUPERFAMILY SSF53697 96 252 1.61E-25 T 12-10-2018 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 Gene3D G3DSA:3.30.9.10 131 342 1.3E-42 T 12-10-2018 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 PRINTS PR00162 Rieske 2Fe-2S subunit signature 494 506 4.2E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 PRINTS PR00162 Rieske 2Fe-2S subunit signature 482 494 4.2E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 PRINTS PR00162 Rieske 2Fe-2S subunit signature 461 472 4.2E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 Gene3D G3DSA:3.50.50.60 38 384 1.3E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 Gene3D G3DSA:2.102.10.10 414 517 2.9E-23 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 Pfam PF00355 Rieske [2Fe-2S] domain 430 509 8.9E-14 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 SUPERFAMILY SSF51905 35 391 2.07E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 Pfam PF01266 FAD dependent oxidoreductase 38 382 1.1E-43 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 NPD12_1752 613003a191e22577ed2dd8166afb83e6 521 SUPERFAMILY SSF50022 395 509 5.11E-24 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.5E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 Gene3D G3DSA:1.10.10.10 1 91 5.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 SUPERFAMILY SSF53850 90 291 1.09E-39 T 12-10-2018 NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 Pfam PF03466 LysR substrate binding domain 89 291 4.4E-46 T 12-10-2018 IPR005119 LysR, substrate-binding NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 Gene3D G3DSA:3.40.190.290 92 293 4.1E-48 T 12-10-2018 NPD12_61 6bbeadfb0c4e7859ec57a0600e2a8930 293 SUPERFAMILY SSF46785 1 111 2.2E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 406 44.082 T 12-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 Gene3D G3DSA:3.40.50.620 1 223 1.4E-88 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 SUPERFAMILY SSF52374 3 319 1.43E-105 T 12-10-2018 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 Gene3D G3DSA:1.10.240.10 224 325 1.4E-36 T 12-10-2018 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 Pfam PF00579 tRNA synthetases class I (W and Y) 30 319 3.1E-84 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 Pfam PF01479 S4 domain 343 385 1.3E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 406 4.7E-137 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 Gene3D G3DSA:3.10.290.10 326 407 3.0E-22 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 SUPERFAMILY SSF55174 303 406 2.22E-18 T 12-10-2018 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 214 226 5.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 5.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 5.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_3452 92cc01b710920195798d0de33af5e6ea 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 5.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 SUPERFAMILY SSF52540 326 568 2.19E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 Pfam PF00005 ABC transporter 349 498 1.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 Gene3D G3DSA:3.40.50.300 319 570 5.6E-80 T 12-10-2018 NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 Gene3D G3DSA:1.20.1560.10 2 318 1.9E-56 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 SUPERFAMILY SSF90123 5 316 1.57E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 SMART SM00382 358 544 5.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 Pfam PF00664 ABC transporter transmembrane region 23 287 9.0E-29 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_3475 929135fdcdf498e511ffa6dafea982d5 577 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 Gene3D G3DSA:3.90.1150.10 14 384 1.8E-139 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 Pfam PF00155 Aminotransferase class I and II 31 385 1.4E-53 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 Gene3D G3DSA:3.40.640.10 44 281 1.8E-139 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 160 184 1.0E-11 T 12-10-2018 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 226 250 1.0E-11 T 12-10-2018 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 90 110 1.0E-11 T 12-10-2018 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 112 133 1.0E-11 T 12-10-2018 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 NPD12_1954 e8c0534670518cdfcebd93c61ce8ad38 396 SUPERFAMILY SSF53383 1 392 4.21E-96 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2938 21840816a4c8964913ebcd34fc85aa3c 464 Gene3D G3DSA:2.30.40.10 4 456 4.9E-171 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2938 21840816a4c8964913ebcd34fc85aa3c 464 SUPERFAMILY SSF51556 53 383 4.77E-99 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_2938 21840816a4c8964913ebcd34fc85aa3c 464 Gene3D G3DSA:3.20.20.140 53 424 4.9E-171 T 12-10-2018 NPD12_2938 21840816a4c8964913ebcd34fc85aa3c 464 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 455 2.0E-175 T 12-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 NPD12_2938 21840816a4c8964913ebcd34fc85aa3c 464 SUPERFAMILY SSF51338 352 458 5.18E-39 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2938 21840816a4c8964913ebcd34fc85aa3c 464 Pfam PF01979 Amidohydrolase family 49 436 8.9E-26 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 NPD12_2938 21840816a4c8964913ebcd34fc85aa3c 464 SUPERFAMILY SSF51338 1 64 6.48E-18 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_424 ddaf36f7b7d94995fe33601b2bd77feb 333 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 2.8E-155 T 12-10-2018 IPR010894 Stage V sporulation AD NPD12_424 ddaf36f7b7d94995fe33601b2bd77feb 333 PIRSF PIRSF011570 1 333 3.4E-160 T 12-10-2018 IPR010894 Stage V sporulation AD NPD12_424 ddaf36f7b7d94995fe33601b2bd77feb 333 Gene3D G3DSA:3.40.47.40 1 333 1.7E-149 T 12-10-2018 IPR038369 Stage V sporulation AD superfamily NPD12_424 ddaf36f7b7d94995fe33601b2bd77feb 333 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 3.2E-158 T 12-10-2018 IPR010894 Stage V sporulation AD NPD12_424 ddaf36f7b7d94995fe33601b2bd77feb 333 SUPERFAMILY SSF53901 25 309 9.52E-16 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_2892 9c1fe423aa79e2c254df1ab9dd0f4736 86 Gene3D G3DSA:1.10.150.20 1 86 1.1E-31 T 12-10-2018 NPD12_2892 9c1fe423aa79e2c254df1ab9dd0f4736 86 Pfam PF04994 TfoX C-terminal domain 3 78 7.1E-24 T 12-10-2018 IPR007077 TfoX, C-terminal NPD12_3118 dff9943ef8fb94777508b45e81c97af5 212 SUPERFAMILY SSF52540 9 198 6.81E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3118 dff9943ef8fb94777508b45e81c97af5 212 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 10 195 8.6E-47 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 NPD12_3118 dff9943ef8fb94777508b45e81c97af5 212 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 7 204 24.818 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 NPD12_3118 dff9943ef8fb94777508b45e81c97af5 212 Gene3D G3DSA:3.40.50.300 3 208 6.5E-64 T 12-10-2018 NPD12_3118 dff9943ef8fb94777508b45e81c97af5 212 Pfam PF01121 Dephospho-CoA kinase 10 187 5.6E-50 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 NPD12_1193 6424036c48326c1081c3e81403dae450 557 SUPERFAMILY SSF52540 250 498 1.7E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1193 6424036c48326c1081c3e81403dae450 557 Gene3D G3DSA:1.10.8.60 417 496 2.3E-11 T 12-10-2018 NPD12_1193 6424036c48326c1081c3e81403dae450 557 Gene3D G3DSA:3.40.50.300 242 415 5.7E-38 T 12-10-2018 NPD12_1193 6424036c48326c1081c3e81403dae450 557 SUPERFAMILY SSF52540 82 232 3.55E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1193 6424036c48326c1081c3e81403dae450 557 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 287 415 3.2E-28 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_1193 6424036c48326c1081c3e81403dae450 557 SMART SM00382 283 418 4.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_236 8200cadafcd76b0982baa1c407677984 181 SUPERFAMILY SSF110455 1 114 3.92E-32 T 12-10-2018 NPD12_236 8200cadafcd76b0982baa1c407677984 181 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 173 1.5E-46 T 12-10-2018 IPR004466 Ribonuclease M5 GO:0043822 NPD12_236 8200cadafcd76b0982baa1c407677984 181 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 175 29.878 T 12-10-2018 IPR004466 Ribonuclease M5 GO:0043822 NPD12_236 8200cadafcd76b0982baa1c407677984 181 Pfam PF13331 Domain of unknown function (DUF4093) 89 173 1.7E-27 T 12-10-2018 IPR025156 Ribonuclease M5, C-terminal domain NPD12_236 8200cadafcd76b0982baa1c407677984 181 Gene3D G3DSA:3.40.1360.20 1 118 1.5E-22 T 12-10-2018 NPD12_236 8200cadafcd76b0982baa1c407677984 181 SMART SM00493 3 76 1.2E-8 T 12-10-2018 IPR006171 TOPRIM domain NPD12_236 8200cadafcd76b0982baa1c407677984 181 Pfam PF01751 Toprim domain 4 80 3.8E-8 T 12-10-2018 IPR006171 TOPRIM domain NPD12_3615 42e08820223156d69fd8f9b63d469858 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.024 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 NPD12_3615 42e08820223156d69fd8f9b63d469858 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.4E-28 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 NPD12_3615 42e08820223156d69fd8f9b63d469858 72 SUPERFAMILY SSF50249 1 70 2.86E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3615 42e08820223156d69fd8f9b63d469858 72 Gene3D G3DSA:2.40.50.140 1 72 2.5E-36 T 12-10-2018 NPD12_3615 42e08820223156d69fd8f9b63d469858 72 SMART SM00316 2 72 0.0011 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_3615 42e08820223156d69fd8f9b63d469858 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 6.0E-37 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 NPD12_2053 a34f4b75ee4b954e65fc70ea4f922f7a 131 Pfam PF03780 Asp23 family, cell envelope-related function 11 117 1.0E-37 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 NPD12_3695 f23010430163da0d7a510627a3ea8e6b 323 SUPERFAMILY SSF51395 10 317 3.85E-88 T 12-10-2018 NPD12_3695 f23010430163da0d7a510627a3ea8e6b 323 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 319 5.8E-114 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 NPD12_3695 f23010430163da0d7a510627a3ea8e6b 323 PIRSF PIRSF006621 1 321 1.3E-106 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 NPD12_3695 f23010430163da0d7a510627a3ea8e6b 323 Pfam PF01207 Dihydrouridine synthase (Dus) 14 313 1.3E-95 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 NPD12_3695 f23010430163da0d7a510627a3ea8e6b 323 Gene3D G3DSA:1.10.1200.80 251 321 1.7E-13 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 NPD12_3695 f23010430163da0d7a510627a3ea8e6b 323 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 95 113 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 NPD12_3695 f23010430163da0d7a510627a3ea8e6b 323 Gene3D G3DSA:3.20.20.70 7 249 5.5E-89 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2181 54310920b521c997f42edaa080b3a361 70 Pfam PF09855 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) 8 69 1.6E-32 T 12-10-2018 IPR018652 Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon NPD12_1408 e4e3ccacd7108a7add7cf24a7b76e02e 322 Gene3D G3DSA:3.20.20.140 1 321 3.6E-103 T 12-10-2018 NPD12_1408 e4e3ccacd7108a7add7cf24a7b76e02e 322 SUPERFAMILY SSF51556 1 322 1.36E-78 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_1408 e4e3ccacd7108a7add7cf24a7b76e02e 322 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 3 320 1.8E-91 T 12-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 NPD12_2395 7ca8849fd46c5ef93bf8dcbd5c8e0b07 327 Gene3D G3DSA:2.40.30.10 63 160 1.0E-12 T 12-10-2018 NPD12_2395 7ca8849fd46c5ef93bf8dcbd5c8e0b07 327 SUPERFAMILY SSF63380 66 161 1.29E-13 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel NPD12_2395 7ca8849fd46c5ef93bf8dcbd5c8e0b07 327 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 290 298 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 NPD12_2395 7ca8849fd46c5ef93bf8dcbd5c8e0b07 327 SUPERFAMILY SSF52343 172 320 6.62E-11 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_2395 7ca8849fd46c5ef93bf8dcbd5c8e0b07 327 PIRSF PIRSF006816 62 313 1.4E-31 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 NPD12_2704 04732a77533c9c4e481d6f0c062fd773 334 SUPERFAMILY SSF117143 91 294 8.89E-33 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like NPD12_2704 04732a77533c9c4e481d6f0c062fd773 334 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 205 314 4.5E-26 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G NPD12_2704 04732a77533c9c4e481d6f0c062fd773 334 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 186 2.2E-37 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G NPD12_2704 04732a77533c9c4e481d6f0c062fd773 334 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 247 332 9.8E-23 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain NPD12_2704 04732a77533c9c4e481d6f0c062fd773 334 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site NPD12_2704 04732a77533c9c4e481d6f0c062fd773 334 Pfam PF00460 Flagella basal body rod protein 5 35 3.0E-12 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 NPD12_2608 7151330d6ecb7fd9f31b581ca6d97d5f 137 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 136 26.74 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 NPD12_2608 7151330d6ecb7fd9f31b581ca6d97d5f 137 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 133 1.7E-43 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 NPD12_2608 7151330d6ecb7fd9f31b581ca6d97d5f 137 Gene3D G3DSA:3.30.420.140 1 137 9.9E-51 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 NPD12_2608 7151330d6ecb7fd9f31b581ca6d97d5f 137 SUPERFAMILY SSF53098 1 135 1.08E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_2608 7151330d6ecb7fd9f31b581ca6d97d5f 137 Pfam PF03652 Holliday junction resolvase 1 134 3.1E-45 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 NPD12_2608 7151330d6ecb7fd9f31b581ca6d97d5f 137 SMART SM00732 1 101 1.3E-39 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 NPD12_107 efc7b0ec2a082fa8e56e6ed1bbf20cfc 94 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.0E-29 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_107 efc7b0ec2a082fa8e56e6ed1bbf20cfc 94 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 20.282 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 NPD12_107 efc7b0ec2a082fa8e56e6ed1bbf20cfc 94 Gene3D G3DSA:3.30.70.60 1 94 3.0E-35 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 NPD12_107 efc7b0ec2a082fa8e56e6ed1bbf20cfc 94 SUPERFAMILY SSF54995 1 93 2.75E-35 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_107 efc7b0ec2a082fa8e56e6ed1bbf20cfc 94 Pfam PF01250 Ribosomal protein S6 3 91 2.1E-32 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Gene3D G3DSA:4.10.1280.10 361 425 1.3E-41 T 12-10-2018 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 SUPERFAMILY SSF49899 873 1079 1.13E-52 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 SUPERFAMILY SSF55486 3 546 4.03E-193 T 12-10-2018 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 SUPERFAMILY SSF50386 1080 1295 9.94E-82 T 12-10-2018 IPR011065 Kunitz inhibitor STI-like superfamily NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Gene3D G3DSA:3.90.1240.10 439 540 1.0E-27 T 12-10-2018 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 PRINTS PR00760 Bontoxilysin signature 7 23 1.6E-30 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 PRINTS PR00760 Bontoxilysin signature 213 225 1.6E-30 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 PRINTS PR00760 Bontoxilysin signature 33 49 1.6E-30 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 PRINTS PR00760 Bontoxilysin signature 97 119 1.6E-30 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 PRINTS PR00760 Bontoxilysin signature 259 275 1.6E-30 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 PRINTS PR00760 Bontoxilysin signature 72 88 1.6E-30 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Pfam PF07951 Clostridium neurotoxin, C-terminal receptor binding 1088 1293 4.9E-99 T 12-10-2018 IPR013104 Clostridium neurotoxin, receptor-binding C-terminal GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Gene3D G3DSA:1.20.1120.10 549 869 6.9E-156 T 12-10-2018 IPR036248 Clostridium neurotoxin, translocation domain NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Pfam PF07953 Clostridium neurotoxin, N-terminal receptor binding 886 1079 3.1E-79 T 12-10-2018 IPR012928 Clostridium neurotoxin, receptor binding N-terminal GO:0005576|GO:0009405|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Pfam PF01742 Clostridial neurotoxin zinc protease 4 410 1.5E-186 T 12-10-2018 IPR000395 Botulinum/Tetanus toxin, catalytic chain GO:0004222|GO:0006508|GO:0008270|GO:0046929 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Gene3D G3DSA:3.90.1240.10 8 250 1.3E-99 T 12-10-2018 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 SUPERFAMILY SSF58091 549 874 1.18E-123 T 12-10-2018 IPR036248 Clostridium neurotoxin, translocation domain NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Gene3D G3DSA:1.20.58.540 258 360 2.5E-41 T 12-10-2018 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Gene3D G3DSA:2.80.10.50 1100 1296 4.1E-87 T 12-10-2018 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Gene3D G3DSA:2.60.120.200 870 1099 1.6E-59 T 12-10-2018 NPD12_949 fa28976dd234774b0732022e9cf8871b 1296 Pfam PF07952 Clostridium neurotoxin, Translocation domain 549 866 1.7E-174 T 12-10-2018 IPR012500 Clostridium neurotoxin, translocation GO:0008320|GO:0009405|GO:0046929 NPD12_2054 2be659d3ba949bfb3213180d886c2669 174 Pfam PF12685 SpoIIIAH-like protein 45 170 1.2E-29 T 12-10-2018 IPR024232 Stage III sporulation protein AH-like NPD12_2054 2be659d3ba949bfb3213180d886c2669 174 Gene3D G3DSA:3.30.300.270 61 174 9.0E-23 T 12-10-2018 IPR038503 Stage III sporulation protein AH-like superfamily NPD12_1755 368882e77652ee015bef0cb72754d6f6 378 SUPERFAMILY SSF51430 1 317 5.24E-66 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_1755 368882e77652ee015bef0cb72754d6f6 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 349 360 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1755 368882e77652ee015bef0cb72754d6f6 378 Gene3D G3DSA:1.10.1060.10 288 376 3.9E-10 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_1755 368882e77652ee015bef0cb72754d6f6 378 Gene3D G3DSA:3.20.20.100 1 287 3.1E-63 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_1755 368882e77652ee015bef0cb72754d6f6 378 Pfam PF13534 4Fe-4S dicluster domain 298 363 2.1E-10 T 12-10-2018 NPD12_1755 368882e77652ee015bef0cb72754d6f6 378 SUPERFAMILY SSF46548 290 370 2.14E-11 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_1755 368882e77652ee015bef0cb72754d6f6 378 Pfam PF00248 Aldo/keto reductase family 16 284 5.2E-37 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain NPD12_2187 b074964b1bd2ac65fec38501781631d1 451 Gene3D G3DSA:1.20.1250.20 2 214 4.4E-41 T 12-10-2018 NPD12_2187 b074964b1bd2ac65fec38501781631d1 451 Pfam PF07690 Major Facilitator Superfamily 23 392 2.2E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_2187 b074964b1bd2ac65fec38501781631d1 451 Gene3D G3DSA:1.20.1250.20 215 449 6.6E-42 T 12-10-2018 NPD12_2187 b074964b1bd2ac65fec38501781631d1 451 SUPERFAMILY SSF103473 1 430 1.2E-36 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_1685 85b1975d072a6c4f1ce57a22f6646172 535 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 358 508 4.5E-20 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain NPD12_1685 85b1975d072a6c4f1ce57a22f6646172 535 PIRSF PIRSF038958 1 525 5.0E-101 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type NPD12_1685 85b1975d072a6c4f1ce57a22f6646172 535 Pfam PF01943 Polysaccharide biosynthesis protein 7 305 4.0E-28 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 Gene3D G3DSA:3.40.50.2300 1 121 9.1E-33 T 12-10-2018 NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 Gene3D G3DSA:1.10.10.10 123 228 5.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 SUPERFAMILY SSF46894 129 224 1.7E-29 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 SMART SM00448 2 112 8.0E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 SUPERFAMILY SSF52172 3 118 7.68E-37 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 SMART SM00862 148 224 4.0E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 Pfam PF00072 Response regulator receiver domain 4 113 9.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1227 49b126a7a9bedabf905a3aa68401912b 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 4.7E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_3751 7509571c2c44eca930691aa74741cfba 142 TIGRFAM TIGR01712 phage_N6A_met: phage N-6-adenine-methyltransferase 9 126 5.3E-30 T 12-10-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 NPD12_3751 7509571c2c44eca930691aa74741cfba 142 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 63 69 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_3751 7509571c2c44eca930691aa74741cfba 142 Pfam PF05869 DNA N-6-adenine-methyltransferase (Dam) 9 130 2.2E-37 T 12-10-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Gene3D G3DSA:1.10.1790.10 444 544 9.0E-23 T 12-10-2018 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Gene3D G3DSA:1.10.1790.10 808 907 3.3E-12 T 12-10-2018 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 178 193 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Pfam PF00158 Sigma-54 interaction domain 83 247 5.9E-45 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 SUPERFAMILY SSF63520 444 544 2.88E-22 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Pfam PF00874 PRD domain 454 540 1.3E-18 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Pfam PF00874 PRD domain 817 904 3.0E-16 T 12-10-2018 IPR011608 PRD domain GO:0006355 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Gene3D G3DSA:3.40.50.300 69 258 2.4E-39 T 12-10-2018 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 SUPERFAMILY SSF52540 76 318 4.78E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 SUPERFAMILY SSF63520 806 904 3.4E-16 T 12-10-2018 IPR036634 PRD domain superfamily GO:0006355 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Gene3D G3DSA:3.40.50.510 550 683 9.0E-43 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 SUPERFAMILY SSF53062 553 677 6.8E-21 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 SMART SM00382 105 259 6.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3503 fbe99c88689f61245a8bc965bfab4be5 909 Pfam PF03610 PTS system fructose IIA component 554 653 1.3E-13 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 NPD12_2406 449b8906887223fe6fe9791ee7104d25 306 SMART SM00382 29 212 4.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2406 449b8906887223fe6fe9791ee7104d25 306 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2406 449b8906887223fe6fe9791ee7104d25 306 Gene3D G3DSA:3.40.50.300 1 267 4.0E-59 T 12-10-2018 NPD12_2406 449b8906887223fe6fe9791ee7104d25 306 SUPERFAMILY SSF52540 4 224 1.02E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2406 449b8906887223fe6fe9791ee7104d25 306 Pfam PF00005 ABC transporter 20 161 2.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_991 9948a3bf71bc0036aee93ac82b5f190c 293 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 187 277 1.5E-11 T 12-10-2018 IPR000772 Ricin B, lectin domain NPD12_991 9948a3bf71bc0036aee93ac82b5f190c 293 SUPERFAMILY SSF50370 154 290 1.31E-30 T 12-10-2018 IPR035992 Ricin B-like lectins NPD12_991 9948a3bf71bc0036aee93ac82b5f190c 293 SUPERFAMILY SSF50370 7 145 5.94E-20 T 12-10-2018 IPR035992 Ricin B-like lectins NPD12_991 9948a3bf71bc0036aee93ac82b5f190c 293 Gene3D G3DSA:2.80.10.50 153 292 8.0E-42 T 12-10-2018 NPD12_991 9948a3bf71bc0036aee93ac82b5f190c 293 Gene3D G3DSA:2.80.10.50 1 152 5.4E-42 T 12-10-2018 NPD12_991 9948a3bf71bc0036aee93ac82b5f190c 293 SMART SM00458 154 291 4.6E-24 T 12-10-2018 IPR000772 Ricin B, lectin domain NPD12_991 9948a3bf71bc0036aee93ac82b5f190c 293 SMART SM00458 12 143 2.4E-12 T 12-10-2018 IPR000772 Ricin B, lectin domain NPD12_2275 94359edfa3a64a9438c9a309326af1fd 291 SUPERFAMILY SSF52540 3 224 5.44E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2275 94359edfa3a64a9438c9a309326af1fd 291 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2275 94359edfa3a64a9438c9a309326af1fd 291 Pfam PF00005 ABC transporter 23 164 8.3E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2275 94359edfa3a64a9438c9a309326af1fd 291 Gene3D G3DSA:3.40.50.300 1 236 2.9E-65 T 12-10-2018 NPD12_2275 94359edfa3a64a9438c9a309326af1fd 291 SMART SM00382 32 214 1.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2631 3a7377151b92dcfb388fe933d9260cd8 336 Gene3D G3DSA:3.40.47.10 1 336 7.0E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_2631 3a7377151b92dcfb388fe933d9260cd8 336 SUPERFAMILY SSF53901 4 186 8.77E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_2631 3a7377151b92dcfb388fe933d9260cd8 336 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 197 3.5E-18 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_2631 3a7377151b92dcfb388fe933d9260cd8 336 SUPERFAMILY SSF53901 193 332 6.33E-16 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_2631 3a7377151b92dcfb388fe933d9260cd8 336 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 255 334 4.9E-17 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_619 e3f64a1acedeff21b35d1b696e490eea 266 Pfam PF08543 Phosphomethylpyrimidine kinase 11 252 1.4E-98 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 NPD12_619 e3f64a1acedeff21b35d1b696e490eea 266 SUPERFAMILY SSF53613 1 259 7.17E-85 T 12-10-2018 IPR029056 Ribokinase-like NPD12_619 e3f64a1acedeff21b35d1b696e490eea 266 Gene3D G3DSA:3.40.1190.20 1 264 8.6E-104 T 12-10-2018 IPR029056 Ribokinase-like NPD12_619 e3f64a1acedeff21b35d1b696e490eea 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 255 6.2E-103 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_449 e278803a1a273f7f908d6126815c71d9 184 Pfam PF06210 Protein of unknown function (DUF1003) 69 169 9.8E-37 T 12-10-2018 IPR010406 Protein of unknown function DUF1003 NPD12_1421 f4b1f5dc7e2cd04e806060469fda045d 163 Gene3D G3DSA:3.20.90.20 1 159 7.1E-9 T 12-10-2018 IPR038595 LURP-one-related superfamily NPD12_1421 f4b1f5dc7e2cd04e806060469fda045d 163 Pfam PF04525 LURP-one-related 3 149 3.3E-15 T 12-10-2018 IPR007612 LURP-one-related NPD12_1421 f4b1f5dc7e2cd04e806060469fda045d 163 SUPERFAMILY SSF54518 2 154 2.07E-32 T 12-10-2018 IPR025659 Tubby-like, C-terminal NPD12_2648 e68bddd3b1c43fb5553507087bfbda79 407 Gene3D G3DSA:3.40.50.720 102 267 6.6E-26 T 12-10-2018 NPD12_2648 e68bddd3b1c43fb5553507087bfbda79 407 SUPERFAMILY SSF51735 114 256 1.32E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2648 e68bddd3b1c43fb5553507087bfbda79 407 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 119 261 5.4E-6 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 NPD12_1709 7c9f28eb44d3a545cfce29bf11872869 317 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1709 7c9f28eb44d3a545cfce29bf11872869 317 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 317 21.538 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1709 7c9f28eb44d3a545cfce29bf11872869 317 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 6.9E-6 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1709 7c9f28eb44d3a545cfce29bf11872869 317 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 16 316 2.6E-92 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1709 7c9f28eb44d3a545cfce29bf11872869 317 ProSitePatterns PS01348 MraY family signature 2. 164 175 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1709 7c9f28eb44d3a545cfce29bf11872869 317 Pfam PF00953 Glycosyl transferase family 4 78 244 5.1E-32 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 NPD12_3628 a80b106f2828c498017a7d92438032bc 105 Pfam PF00467 KOW motif 8 39 2.9E-6 T 12-10-2018 IPR005824 KOW NPD12_3628 a80b106f2828c498017a7d92438032bc 105 Gene3D G3DSA:2.30.30.30 1 104 2.1E-38 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 NPD12_3628 a80b106f2828c498017a7d92438032bc 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 41 104 3.1E-28 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3628 a80b106f2828c498017a7d92438032bc 105 SMART SM00739 5 32 4.5E-5 T 12-10-2018 IPR005824 KOW NPD12_3628 a80b106f2828c498017a7d92438032bc 105 SUPERFAMILY SSF50104 2 103 6.47E-35 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily NPD12_3628 a80b106f2828c498017a7d92438032bc 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 4 99 19.506 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3628 a80b106f2828c498017a7d92438032bc 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 4 104 1.1E-37 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_1643 58500c554c69b19315403126768b22ef 217 Gene3D G3DSA:3.40.50.12740 5 216 2.0E-64 T 12-10-2018 NPD12_1643 58500c554c69b19315403126768b22ef 217 SMART SM00421 153 210 8.0E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1643 58500c554c69b19315403126768b22ef 217 SMART SM00448 4 117 7.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1643 58500c554c69b19315403126768b22ef 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 7.5E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1643 58500c554c69b19315403126768b22ef 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1643 58500c554c69b19315403126768b22ef 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1643 58500c554c69b19315403126768b22ef 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 NPD12_1643 58500c554c69b19315403126768b22ef 217 Pfam PF00072 Response regulator receiver domain 6 114 8.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1643 58500c554c69b19315403126768b22ef 217 SUPERFAMILY SSF52172 3 133 3.13E-32 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1643 58500c554c69b19315403126768b22ef 217 SUPERFAMILY SSF46894 149 216 1.19E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_3110 0c11656dcac6f819f758567c4c09cb65 194 Pfam PF02545 Maf-like protein 4 189 3.2E-59 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 NPD12_3110 0c11656dcac6f819f758567c4c09cb65 194 Gene3D G3DSA:3.90.950.10 1 194 4.2E-68 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like NPD12_3110 0c11656dcac6f819f758567c4c09cb65 194 Hamap MF_00528 Septum formation protein Maf [maf]. 3 194 31.088 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 NPD12_3110 0c11656dcac6f819f758567c4c09cb65 194 PIRSF PIRSF006305 1 194 1.1E-61 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 NPD12_3110 0c11656dcac6f819f758567c4c09cb65 194 SUPERFAMILY SSF52972 3 189 9.81E-61 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like NPD12_3110 0c11656dcac6f819f758567c4c09cb65 194 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 187 3.3E-58 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 NPD12_3220 b10626df24203983f8dd5b028cd1edee 1070 Gene3D G3DSA:3.40.630.40 886 1068 2.9E-62 T 12-10-2018 NPD12_3220 b10626df24203983f8dd5b028cd1edee 1070 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 890 1065 1.0E-55 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3220 b10626df24203983f8dd5b028cd1edee 1070 SMART SM00646 956 1065 1.1E-43 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3220 b10626df24203983f8dd5b028cd1edee 1070 Gene3D G3DSA:2.60.40.10 33 140 2.7E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_3220 b10626df24203983f8dd5b028cd1edee 1070 SUPERFAMILY SSF53187 888 1066 1.54E-59 T 12-10-2018 NPD12_1238 e1b06f9d572244c3e00f631489aefcae 316 Gene3D G3DSA:1.10.3470.10 5 315 7.7E-50 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1238 e1b06f9d572244c3e00f631489aefcae 316 SUPERFAMILY SSF81345 5 312 2.09E-52 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1238 e1b06f9d572244c3e00f631489aefcae 316 Pfam PF01032 FecCD transport family 17 312 4.3E-48 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 Gene3D G3DSA:1.10.4030.30 38 313 5.1E-50 T 12-10-2018 NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 223 244 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 Gene3D G3DSA:3.10.50.40 195 288 5.1E-50 T 12-10-2018 NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 SUPERFAMILY SSF109998 36 224 1.61E-32 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 Pfam PF13624 SurA N-terminal domain 4 164 9.6E-21 T 12-10-2018 NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 Hamap MF_01145 Foldase protein PrsA [prsA]. 5 336 16.507 T 12-10-2018 IPR023059 Foldase protein PrsA GO:0003755 NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 Pfam PF13145 PPIC-type PPIASE domain 174 300 5.4E-22 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 NPD12_8 ab46f43ea16308e82a65c7e47987b12c 336 SUPERFAMILY SSF54534 194 289 6.36E-25 T 12-10-2018 NPD12_776 376fa2082f384876d9a16d63296a0d04 106 Pfam PF03551 Transcriptional regulator PadR-like family 19 87 1.7E-13 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal NPD12_776 376fa2082f384876d9a16d63296a0d04 106 Gene3D G3DSA:1.10.10.10 10 106 8.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_776 376fa2082f384876d9a16d63296a0d04 106 SUPERFAMILY SSF46785 18 91 2.23E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1637 0d7e41a927f23c4956735118cd631407 157 Gene3D G3DSA:1.10.10.10 33 83 2.9E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1637 0d7e41a927f23c4956735118cd631407 157 SUPERFAMILY SSF88659 36 78 6.92E-5 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_1637 0d7e41a927f23c4956735118cd631407 157 Pfam PF02001 Protein of unknown function DUF134 3 96 6.8E-23 T 12-10-2018 IPR002852 Uncharacterised protein family UPF0251 NPD12_1637 0d7e41a927f23c4956735118cd631407 157 Hamap MF_00674 UPF0251 protein . 2 98 24.629 T 12-10-2018 IPR002852 Uncharacterised protein family UPF0251 NPD12_3201 4da69b44919972b7e56de1498fb34f58 238 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 227 5.2E-54 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 NPD12_3201 4da69b44919972b7e56de1498fb34f58 238 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 57 220 4.5E-58 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 NPD12_3201 4da69b44919972b7e56de1498fb34f58 238 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 1 236 59.071 T 12-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 NPD12_786 60f0d0cb4536674c3165fc4e216c71c3 238 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 100 219 1.1E-36 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 NPD12_786 60f0d0cb4536674c3165fc4e216c71c3 238 Gene3D G3DSA:3.30.1380.10 37 238 1.8E-66 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_786 60f0d0cb4536674c3165fc4e216c71c3 238 SUPERFAMILY SSF55166 80 227 2.28E-33 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_1940 2d9ade1645073653edb254218e301cb8 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 46 60 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 NPD12_1940 2d9ade1645073653edb254218e301cb8 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 NPD12_1940 2d9ade1645073653edb254218e301cb8 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 67 9.6E-27 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 NPD12_1940 2d9ade1645073653edb254218e301cb8 67 Gene3D G3DSA:1.10.8.910 8 67 7.1E-24 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily NPD12_1006 c47f7b1542ef2544bc00fdd3405d1a30 520 Pfam PF04294 VanW like protein 245 374 1.0E-51 T 12-10-2018 IPR007391 Vancomycin resistance VanW NPD12_1006 c47f7b1542ef2544bc00fdd3405d1a30 520 SMART SM01208 382 459 1.4E-17 T 12-10-2018 IPR011098 G5 domain NPD12_1006 c47f7b1542ef2544bc00fdd3405d1a30 520 Gene3D G3DSA:2.20.230.10 388 458 2.5E-10 T 12-10-2018 NPD12_1006 c47f7b1542ef2544bc00fdd3405d1a30 520 Pfam PF07501 G5 domain 391 458 1.9E-12 T 12-10-2018 IPR011098 G5 domain NPD12_1006 c47f7b1542ef2544bc00fdd3405d1a30 520 Pfam PF12229 Putative peptidoglycan binding domain 94 206 8.6E-22 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain NPD12_1541 23b8f49158684262739401b911a777e5 217 Hamap MF_00494 Probable transaldolase [tal]. 1 214 46.671 T 12-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 NPD12_1541 23b8f49158684262739401b911a777e5 217 SUPERFAMILY SSF51569 1 213 1.15E-79 T 12-10-2018 NPD12_1541 23b8f49158684262739401b911a777e5 217 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 NPD12_1541 23b8f49158684262739401b911a777e5 217 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 NPD12_1541 23b8f49158684262739401b911a777e5 217 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 213 4.9E-99 T 12-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 NPD12_1541 23b8f49158684262739401b911a777e5 217 Gene3D G3DSA:3.20.20.70 1 217 7.2E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1541 23b8f49158684262739401b911a777e5 217 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 208 6.4E-61 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 NPD12_1877 ca06fa1cfdbc40db72b2aea615e4a2c6 493 SUPERFAMILY SSF53686 2 491 3.26E-138 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme NPD12_1877 ca06fa1cfdbc40db72b2aea615e4a2c6 493 Pfam PF14821 Threonine synthase N terminus 3 78 1.7E-26 T 12-10-2018 IPR029144 Threonine synthase, N-terminal NPD12_1877 ca06fa1cfdbc40db72b2aea615e4a2c6 493 Gene3D G3DSA:3.40.50.1100 106 228 7.2E-130 T 12-10-2018 NPD12_1877 ca06fa1cfdbc40db72b2aea615e4a2c6 493 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 97 414 4.3E-13 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme NPD12_1877 ca06fa1cfdbc40db72b2aea615e4a2c6 493 Gene3D G3DSA:3.40.50.1100 96 442 7.2E-130 T 12-10-2018 NPD12_1877 ca06fa1cfdbc40db72b2aea615e4a2c6 493 Gene3D G3DSA:3.90.1380.10 1 84 1.6E-25 T 12-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily NPD12_1877 ca06fa1cfdbc40db72b2aea615e4a2c6 493 TIGRFAM TIGR00260 thrC: threonine synthase 94 439 3.0E-72 T 12-10-2018 IPR004450 Threonine synthase-like NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 226 237 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 SUPERFAMILY SSF54862 195 257 3.28E-16 T 12-10-2018 NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 SUPERFAMILY SSF52218 1 146 5.37E-20 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 Gene3D G3DSA:3.30.70.20 185 251 6.3E-11 T 12-10-2018 NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 12-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 Pfam PF00037 4Fe-4S binding domain 221 241 7.2E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 Pfam PF00037 4Fe-4S binding domain 195 213 8.4E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 Gene3D G3DSA:3.40.50.360 4 148 2.5E-18 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_175 470ec02caff7c4c0a7a20708cb53276e 262 Pfam PF12724 Flavodoxin domain 5 90 1.1E-9 T 12-10-2018 IPR026816 Flavodoxin domain NPD12_1609 4e613e3d947d7df9c11f8c447bcf1f6c 425 Gene3D G3DSA:3.30.70.20 257 316 3.2E-7 T 12-10-2018 NPD12_1609 4e613e3d947d7df9c11f8c447bcf1f6c 425 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 294 305 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1609 4e613e3d947d7df9c11f8c447bcf1f6c 425 SUPERFAMILY SSF54862 279 363 1.23E-20 T 12-10-2018 NPD12_1609 4e613e3d947d7df9c11f8c447bcf1f6c 425 PRINTS PR01868 ABC transporter family E signature 299 314 3.0E-5 T 12-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 NPD12_1609 4e613e3d947d7df9c11f8c447bcf1f6c 425 PRINTS PR01868 ABC transporter family E signature 328 352 3.0E-5 T 12-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 NPD12_1609 4e613e3d947d7df9c11f8c447bcf1f6c 425 Pfam PF12838 4Fe-4S dicluster domain 293 345 4.0E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_1609 4e613e3d947d7df9c11f8c447bcf1f6c 425 Gene3D G3DSA:3.30.70.20 317 390 1.1E-6 T 12-10-2018 NPD12_1945 760341695b03080a2074ef9b9d562477 201 SUPERFAMILY SSF46785 7 71 6.62E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1945 760341695b03080a2074ef9b9d562477 201 Hamap MF_00015 LexA repressor [lexA]. 4 201 33.639 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 NPD12_1945 760341695b03080a2074ef9b9d562477 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 128 139 1.2E-10 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 NPD12_1945 760341695b03080a2074ef9b9d562477 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 117 127 1.2E-10 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 NPD12_1945 760341695b03080a2074ef9b9d562477 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 156 168 1.2E-10 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 NPD12_1945 760341695b03080a2074ef9b9d562477 201 SUPERFAMILY SSF51306 79 199 6.98E-36 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily NPD12_1945 760341695b03080a2074ef9b9d562477 201 Pfam PF00717 Peptidase S24-like 120 185 9.9E-16 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C NPD12_1945 760341695b03080a2074ef9b9d562477 201 Gene3D G3DSA:1.10.10.10 6 69 1.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1945 760341695b03080a2074ef9b9d562477 201 Pfam PF01726 LexA DNA binding domain 7 66 3.2E-21 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 NPD12_1945 760341695b03080a2074ef9b9d562477 201 TIGRFAM TIGR00498 lexA: repressor LexA 7 200 2.3E-71 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 NPD12_1945 760341695b03080a2074ef9b9d562477 201 Gene3D G3DSA:2.10.109.10 85 201 3.2E-42 T 12-10-2018 NPD12_3737 8c92edacc7c2a6674875a91dc6335fdb 49 SUPERFAMILY SSF47598 10 47 5.34E-5 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 NPD12_3338 28a13732785e9ab892843b39ea1d9d22 192 SUPERFAMILY SSF52540 1 190 5.52E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3338 28a13732785e9ab892843b39ea1d9d22 192 Pfam PF01926 50S ribosome-binding GTPase 25 140 2.9E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_3338 28a13732785e9ab892843b39ea1d9d22 192 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 6 189 7.3E-76 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 NPD12_3338 28a13732785e9ab892843b39ea1d9d22 192 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 190 28.113 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 NPD12_3338 28a13732785e9ab892843b39ea1d9d22 192 Gene3D G3DSA:3.40.50.300 1 191 1.8E-57 T 12-10-2018 NPD12_1410 392fc8cfa55bc6c79d673be27935a6e6 427 Pfam PF02687 FtsX-like permease family 321 419 3.6E-13 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_1410 392fc8cfa55bc6c79d673be27935a6e6 427 Pfam PF12704 MacB-like periplasmic core domain 21 267 3.3E-16 T 12-10-2018 IPR025857 MacB-like periplasmic core domain NPD12_1861 bf2a83873aaf0ce5611302d9b82afbbb 295 SUPERFAMILY SSF51730 1 283 9.02E-89 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like NPD12_1861 bf2a83873aaf0ce5611302d9b82afbbb 295 Gene3D G3DSA:3.20.20.220 2 292 4.5E-99 T 12-10-2018 NPD12_1861 bf2a83873aaf0ce5611302d9b82afbbb 295 Pfam PF02219 Methylenetetrahydrofolate reductase 3 281 1.2E-80 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 NPD12_1861 bf2a83873aaf0ce5611302d9b82afbbb 295 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 14 281 2.5E-97 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 8 173 7.0E-59 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 Pfam PF00467 KOW motif 122 148 7.0E-5 T 12-10-2018 IPR005824 KOW NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 Gene3D G3DSA:3.30.70.940 1 115 8.1E-42 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 PRINTS PR00338 Transcription termination factor NUSG signature 131 146 2.5E-17 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 PRINTS PR00338 Transcription termination factor NUSG signature 149 165 2.5E-17 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 PRINTS PR00338 Transcription termination factor NUSG signature 60 72 2.5E-17 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 5 173 23.385 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 Gene3D G3DSA:2.30.30.30 116 173 3.6E-24 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 ProSitePatterns PS01014 Transcription termination factor nusG signature. 156 165 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 SMART SM00739 119 146 0.0012 T 12-10-2018 IPR005824 KOW NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 Pfam PF02357 Transcription termination factor nusG 7 108 2.4E-29 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 SUPERFAMILY SSF82679 6 112 4.32E-39 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 SMART SM00738 5 113 6.3E-43 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 NPD12_3652 e6be883fecc55dee092604b0990e82d8 174 SUPERFAMILY SSF50104 117 173 5.62E-18 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily NPD12_676 71a1c257bb045c5171e2e9573e487718 264 SMART SM00448 11 122 4.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_676 71a1c257bb045c5171e2e9573e487718 264 SUPERFAMILY SSF52172 8 136 5.55E-33 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_676 71a1c257bb045c5171e2e9573e487718 264 Gene3D G3DSA:3.40.50.2300 3 139 6.8E-32 T 12-10-2018 NPD12_676 71a1c257bb045c5171e2e9573e487718 264 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 150 258 3.2E-22 T 12-10-2018 IPR018745 Domain of unknown function DUF2294 NPD12_676 71a1c257bb045c5171e2e9573e487718 264 Pfam PF00072 Response regulator receiver domain 13 123 8.2E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1429 19b51368b1f0e05ced874b97604c5dfa 349 Pfam PF13303 Phosphotransferase system, EIIC 28 332 2.1E-57 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_1358 bf7d080bcac2f4360360eb9b7c679b4a 210 Pfam PF04961 Formiminotransferase-cyclodeaminase 5 185 9.2E-64 T 12-10-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 NPD12_1358 bf7d080bcac2f4360360eb9b7c679b4a 210 SUPERFAMILY SSF101262 2 206 9.94E-59 T 12-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 NPD12_1358 bf7d080bcac2f4360360eb9b7c679b4a 210 Gene3D G3DSA:1.20.120.680 5 206 4.8E-65 T 12-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 NPD12_3185 82ec52665eecd938df37737685b31172 472 SUPERFAMILY SSF53383 95 469 8.92E-84 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_3185 82ec52665eecd938df37737685b31172 472 SMART SM00345 19 78 9.3E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_3185 82ec52665eecd938df37737685b31172 472 Gene3D G3DSA:3.90.1150.10 106 466 4.2E-98 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_3185 82ec52665eecd938df37737685b31172 472 Gene3D G3DSA:3.40.640.10 141 359 4.2E-98 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_3185 82ec52665eecd938df37737685b31172 472 Pfam PF00155 Aminotransferase class I and II 124 457 1.6E-24 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_3185 82ec52665eecd938df37737685b31172 472 SUPERFAMILY SSF46785 11 82 1.09E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3185 82ec52665eecd938df37737685b31172 472 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 9.6E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_3185 82ec52665eecd938df37737685b31172 472 Gene3D G3DSA:1.10.10.10 8 79 4.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1337 6f83de488ee113230db8c84c07dd3f12 579 SUPERFAMILY SSF53795 345 576 3.89E-16 T 12-10-2018 NPD12_2330 f67e389e263b0f4b26644af94bfac6e3 334 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 35 325 1.1E-97 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 NPD12_2330 f67e389e263b0f4b26644af94bfac6e3 334 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 8 327 3.9E-95 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 NPD12_2330 f67e389e263b0f4b26644af94bfac6e3 334 SUPERFAMILY SSF53659 5 331 1.09E-96 T 12-10-2018 NPD12_2330 f67e389e263b0f4b26644af94bfac6e3 334 Gene3D G3DSA:3.40.718.10 1 331 4.6E-122 T 12-10-2018 NPD12_2527 a015aec4e39ae21c27075c1fc01da060 150 Pfam PF07355 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 20 149 1.6E-14 T 12-10-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 NPD12_959 e470e20c47217f473a2d4d49ab842ef5 262 SUPERFAMILY SSF52540 7 229 3.77E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_959 e470e20c47217f473a2d4d49ab842ef5 262 SMART SM00382 33 215 4.7E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_959 e470e20c47217f473a2d4d49ab842ef5 262 Pfam PF00005 ABC transporter 24 166 3.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_959 e470e20c47217f473a2d4d49ab842ef5 262 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_959 e470e20c47217f473a2d4d49ab842ef5 262 Gene3D G3DSA:3.40.50.300 2 248 3.6E-65 T 12-10-2018 NPD12_3241 ee6fa538462f6bf3f156760f9daae362 220 Pfam PF02080 TrkA-C domain 151 214 9.1E-14 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 NPD12_3241 ee6fa538462f6bf3f156760f9daae362 220 Pfam PF02254 TrkA-N domain 6 121 4.2E-29 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 NPD12_3241 ee6fa538462f6bf3f156760f9daae362 220 Gene3D G3DSA:3.30.70.1450 139 215 1.2E-26 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_3241 ee6fa538462f6bf3f156760f9daae362 220 SUPERFAMILY SSF51735 4 135 1.27E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3241 ee6fa538462f6bf3f156760f9daae362 220 Gene3D G3DSA:3.40.50.720 1 138 1.5E-36 T 12-10-2018 NPD12_3241 ee6fa538462f6bf3f156760f9daae362 220 SUPERFAMILY SSF116726 132 214 2.75E-21 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_505 70d53f9f2a02f9013dc029e92a3533f0 288 SUPERFAMILY SSF52402 31 232 1.04E-45 T 12-10-2018 NPD12_505 70d53f9f2a02f9013dc029e92a3533f0 288 Pfam PF01171 PP-loop family 55 218 2.2E-17 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 NPD12_505 70d53f9f2a02f9013dc029e92a3533f0 288 PIRSF PIRSF004976 9 287 3.5E-69 T 12-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 NPD12_505 70d53f9f2a02f9013dc029e92a3533f0 288 Gene3D G3DSA:3.40.50.620 22 281 4.0E-48 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_435 8d38145528a9562b057cac8a70cb4848 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 3.5E-38 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 3.5E-38 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 3.5E-38 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 3.5E-38 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 3.5E-38 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 3.5E-38 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 170 - T 12-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 Gene3D G3DSA:3.90.110.10 168 441 1.7E-83 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 Pfam PF02056 Family 4 glycosyl hydrolase 6 180 4.3E-48 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 Gene3D G3DSA:3.40.50.720 1 166 8.7E-56 T 12-10-2018 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 SUPERFAMILY SSF51735 3 162 6.78E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_435 8d38145528a9562b057cac8a70cb4848 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 415 1.1E-45 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 NPD12_435 8d38145528a9562b057cac8a70cb4848 441 SUPERFAMILY SSF56327 169 441 1.46E-69 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_143 97167b27f42a3c1ad7c8ee3c2533d72b 893 Pfam PF03699 Uncharacterised protein family (UPF0182) 10 767 1.7E-267 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 NPD12_143 97167b27f42a3c1ad7c8ee3c2533d72b 893 Hamap MF_01600 UPF0182 protein . 1 843 18.122 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 NPD12_2351 7746c7be3135d3f42fb15cd888530644 538 Pfam PF04122 Putative cell wall binding repeat 2 240 325 2.0E-21 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_2351 7746c7be3135d3f42fb15cd888530644 538 Pfam PF04122 Putative cell wall binding repeat 2 135 222 6.1E-16 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_2351 7746c7be3135d3f42fb15cd888530644 538 Pfam PF04122 Putative cell wall binding repeat 2 31 120 2.0E-19 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_2351 7746c7be3135d3f42fb15cd888530644 538 Gene3D G3DSA:3.40.50.12090 164 258 9.2E-8 T 12-10-2018 NPD12_2351 7746c7be3135d3f42fb15cd888530644 538 Gene3D G3DSA:3.40.50.12090 54 153 8.0E-9 T 12-10-2018 NPD12_1133 f9fc771608fd9d60fa6030992380d661 252 Gene3D G3DSA:3.30.950.10 113 232 1.2E-45 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 NPD12_1133 f9fc771608fd9d60fa6030992380d661 252 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 NPD12_1133 f9fc771608fd9d60fa6030992380d661 252 SUPERFAMILY SSF53790 3 249 1.7E-66 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 NPD12_1133 f9fc771608fd9d60fa6030992380d661 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 209 8.3E-45 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 NPD12_1133 f9fc771608fd9d60fa6030992380d661 252 Gene3D G3DSA:3.40.1010.10 1 112 8.0E-31 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 NPD12_1133 f9fc771608fd9d60fa6030992380d661 252 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 5 249 1.1E-100 T 12-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 NPD12_406 4b496e444ce7a40b684f97257e24aba1 233 Gene3D G3DSA:3.40.50.2300 2 128 3.1E-33 T 12-10-2018 NPD12_406 4b496e444ce7a40b684f97257e24aba1 233 SMART SM00448 5 115 2.9E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_406 4b496e444ce7a40b684f97257e24aba1 233 SUPERFAMILY SSF52172 4 181 3.91E-34 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_406 4b496e444ce7a40b684f97257e24aba1 233 SMART SM00862 153 231 1.1E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_406 4b496e444ce7a40b684f97257e24aba1 233 Pfam PF00072 Response regulator receiver domain 7 116 7.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_406 4b496e444ce7a40b684f97257e24aba1 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 2.5E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_406 4b496e444ce7a40b684f97257e24aba1 233 Gene3D G3DSA:1.10.10.10 129 233 8.0E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1886 b277750d9e7b1c20f050b0068b9a9c79 233 Gene3D G3DSA:2.160.20.100 4 127 4.2E-19 T 12-10-2018 NPD12_1886 b277750d9e7b1c20f050b0068b9a9c79 233 SUPERFAMILY SSF141571 24 120 9.42E-20 T 12-10-2018 NPD12_1886 b277750d9e7b1c20f050b0068b9a9c79 233 Pfam PF13599 Pentapeptide repeats (9 copies) 48 120 3.5E-8 T 12-10-2018 IPR001646 Pentapeptide repeat NPD12_2869 2841d5a7d90651f0f2cc59daef2b1259 239 SMART SM00382 29 212 7.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2869 2841d5a7d90651f0f2cc59daef2b1259 239 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2869 2841d5a7d90651f0f2cc59daef2b1259 239 Gene3D G3DSA:3.40.50.300 1 232 1.8E-51 T 12-10-2018 NPD12_2869 2841d5a7d90651f0f2cc59daef2b1259 239 SUPERFAMILY SSF52540 1 225 7.72E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2869 2841d5a7d90651f0f2cc59daef2b1259 239 Pfam PF00005 ABC transporter 21 163 7.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1241 4633c0972b04b90f43e7cb4375536df9 333 Gene3D G3DSA:1.10.10.60 227 332 3.9E-24 T 12-10-2018 NPD12_1241 4633c0972b04b90f43e7cb4375536df9 333 SMART SM00342 245 328 3.6E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1241 4633c0972b04b90f43e7cb4375536df9 333 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 282 324 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_1241 4633c0972b04b90f43e7cb4375536df9 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 7.8E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1241 4633c0972b04b90f43e7cb4375536df9 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 7.8E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1241 4633c0972b04b90f43e7cb4375536df9 333 Pfam PF12833 Helix-turn-helix domain 251 329 1.5E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1241 4633c0972b04b90f43e7cb4375536df9 333 SUPERFAMILY SSF46689 282 330 2.2E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 Gene3D G3DSA:3.40.50.2300 2 131 1.3E-42 T 12-10-2018 NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 SMART SM00448 4 117 1.6E-49 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 SUPERFAMILY SSF46894 128 229 6.24E-33 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 Gene3D G3DSA:1.10.10.10 132 232 4.3E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 Pfam PF00072 Response regulator receiver domain 6 117 4.4E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 6.5E-30 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 SMART SM00862 152 228 5.0E-31 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2575 17e52589f3dc755a948e8d2c65bceb7d 232 SUPERFAMILY SSF52172 2 126 1.12E-46 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2172 624664aaffa00cf3f98c06c250e9c107 448 SUPERFAMILY SSF46785 3 70 2.12E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2172 624664aaffa00cf3f98c06c250e9c107 448 Gene3D G3DSA:3.40.640.10 68 438 4.8E-79 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2172 624664aaffa00cf3f98c06c250e9c107 448 Gene3D G3DSA:1.10.10.10 1 67 2.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2172 624664aaffa00cf3f98c06c250e9c107 448 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 2.0E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2172 624664aaffa00cf3f98c06c250e9c107 448 SMART SM00345 7 66 1.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2172 624664aaffa00cf3f98c06c250e9c107 448 SUPERFAMILY SSF53383 63 437 1.1E-65 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2172 624664aaffa00cf3f98c06c250e9c107 448 Pfam PF00155 Aminotransferase class I and II 98 375 2.6E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1452 d6f4c02253467999c023102ad749435e 512 Gene3D G3DSA:3.40.47.10 184 408 2.4E-9 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_1452 d6f4c02253467999c023102ad749435e 512 PIRSF PIRSF037559 1 512 4.2E-274 T 12-10-2018 IPR017236 Glycine/sarcosine/betaine reductase, component C, beta NPD12_1452 d6f4c02253467999c023102ad749435e 512 SUPERFAMILY SSF53901 184 291 2.24E-12 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_1452 d6f4c02253467999c023102ad749435e 512 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 255 333 3.7E-8 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 NPD12_2141 6415c6518185c6f587d258bc7a13167c 369 Gene3D G3DSA:1.20.1740.10 4 365 1.0E-7 T 12-10-2018 NPD12_2141 6415c6518185c6f587d258bc7a13167c 369 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 360 9.4E-74 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_2141 6415c6518185c6f587d258bc7a13167c 369 Pfam PF03845 Spore germination protein 9 324 2.8E-67 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_852 967299d25ba67010ca2980b2420abad8 187 Pfam PF04542 Sigma-70 region 2 24 92 3.4E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_852 967299d25ba67010ca2980b2420abad8 187 Gene3D G3DSA:1.10.1740.10 4 89 1.6E-13 T 12-10-2018 NPD12_852 967299d25ba67010ca2980b2420abad8 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 177 3.0E-14 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_852 967299d25ba67010ca2980b2420abad8 187 SUPERFAMILY SSF88946 4 104 1.33E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_852 967299d25ba67010ca2980b2420abad8 187 SUPERFAMILY SSF88659 134 177 1.05E-5 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 SMART SM00382 26 230 5.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 Pfam PF09383 NIL domain 260 317 3.9E-5 T 12-10-2018 IPR018449 NIL domain NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 SMART SM00930 247 320 1.7E-4 T 12-10-2018 IPR018449 NIL domain NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 SUPERFAMILY SSF55021 244 319 2.86E-6 T 12-10-2018 NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 Pfam PF00005 ABC transporter 17 165 1.3E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 Gene3D G3DSA:3.40.50.300 1 268 3.9E-75 T 12-10-2018 NPD12_1746 4545b12b5a45239bef704ea1c27a0bcf 320 SUPERFAMILY SSF52540 1 227 1.82E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1805 b2b3beab6ec920f03ef386f80b2b412b 422 SUPERFAMILY SSF55681 7 330 1.81E-58 T 12-10-2018 NPD12_1805 b2b3beab6ec920f03ef386f80b2b412b 422 Pfam PF13393 Histidyl-tRNA synthetase 11 322 3.2E-73 T 12-10-2018 NPD12_1805 b2b3beab6ec920f03ef386f80b2b412b 422 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 380 30.765 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 NPD12_1805 b2b3beab6ec920f03ef386f80b2b412b 422 Gene3D G3DSA:3.30.930.10 2 327 1.2E-86 T 12-10-2018 NPD12_1805 b2b3beab6ec920f03ef386f80b2b412b 422 PIRSF PIRSF001549 4 421 6.4E-79 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 NPD12_1805 b2b3beab6ec920f03ef386f80b2b412b 422 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 13 327 2.5E-106 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 NPD12_3666 36cbf196ff5e8ea3edd4788189a08645 229 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 224 1.1E-75 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 NPD12_3666 36cbf196ff5e8ea3edd4788189a08645 229 SUPERFAMILY SSF53448 4 226 6.07E-61 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_3666 36cbf196ff5e8ea3edd4788189a08645 229 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 3 225 40.629 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 NPD12_3666 36cbf196ff5e8ea3edd4788189a08645 229 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 226 3.0E-63 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 NPD12_3666 36cbf196ff5e8ea3edd4788189a08645 229 Gene3D G3DSA:3.90.550.10 1 228 7.0E-78 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_3666 36cbf196ff5e8ea3edd4788189a08645 229 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 NPD12_3011 382a1376ef42f57e69efe7599a2097e1 380 SMART SM00729 9 225 4.8E-59 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_3011 382a1376ef42f57e69efe7599a2097e1 380 Gene3D G3DSA:3.80.30.20 1 301 2.0E-107 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_3011 382a1376ef42f57e69efe7599a2097e1 380 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 11 358 2.9E-105 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 NPD12_3011 382a1376ef42f57e69efe7599a2097e1 380 SUPERFAMILY SSF102114 7 379 3.01E-113 T 12-10-2018 NPD12_3011 382a1376ef42f57e69efe7599a2097e1 380 Pfam PF04055 Radical SAM superfamily 14 178 1.9E-24 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3011 382a1376ef42f57e69efe7599a2097e1 380 Pfam PF06969 HemN C-terminal domain 305 367 2.3E-12 T 12-10-2018 IPR010723 HemN, C-terminal NPD12_2057 886841e2395050d231b4704e759174b7 387 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 60 381 5.6E-114 T 12-10-2018 IPR014194 Sporulation stage III, protein AE NPD12_2057 886841e2395050d231b4704e759174b7 387 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 1 381 1.5E-148 T 12-10-2018 IPR014194 Sporulation stage III, protein AE NPD12_610 08f76a64d6c2000aba916fb8439b76f3 238 Gene3D G3DSA:3.60.15.10 1 235 2.4E-30 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_610 08f76a64d6c2000aba916fb8439b76f3 238 Pfam PF00753 Metallo-beta-lactamase superfamily 25 184 5.0E-8 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_610 08f76a64d6c2000aba916fb8439b76f3 238 SMART SM00849 21 218 1.9E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_610 08f76a64d6c2000aba916fb8439b76f3 238 SUPERFAMILY SSF56281 3 238 5.9E-27 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1167 5d7e443a116fc63af3d6613e03a09012 154 Pfam PF13673 Acetyltransferase (GNAT) domain 28 144 2.0E-22 T 12-10-2018 IPR000182 GNAT domain NPD12_1167 5d7e443a116fc63af3d6613e03a09012 154 SUPERFAMILY SSF55729 1 153 5.49E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1167 5d7e443a116fc63af3d6613e03a09012 154 Gene3D G3DSA:3.40.630.30 1 153 2.3E-39 T 12-10-2018 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 SUPERFAMILY SSF53822 63 332 1.31E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 Gene3D G3DSA:3.40.50.2300 165 330 9.0E-66 T 12-10-2018 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 Pfam PF13377 Periplasmic binding protein-like domain 174 331 3.8E-25 T 12-10-2018 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 Gene3D G3DSA:1.10.260.40 1 60 1.3E-25 T 12-10-2018 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 SMART SM00354 2 72 5.9E-31 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 Gene3D G3DSA:3.40.50.2300 77 324 9.0E-66 T 12-10-2018 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 SUPERFAMILY SSF47413 2 60 3.34E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1843 6fc58896c3965ed18f39b2429cefdf71 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.5E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 NPD12_1779 abce82e705a6e3075c1051d660608330 289 SUPERFAMILY SSF161111 10 209 1.7E-51 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily NPD12_1779 abce82e705a6e3075c1051d660608330 289 Pfam PF16916 Dimerisation domain of Zinc Transporter 214 288 3.9E-19 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain NPD12_1779 abce82e705a6e3075c1051d660608330 289 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 288 5.0E-67 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 NPD12_1779 abce82e705a6e3075c1051d660608330 289 Gene3D G3DSA:1.20.1510.10 11 208 4.9E-55 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily NPD12_1779 abce82e705a6e3075c1051d660608330 289 SUPERFAMILY SSF160240 211 287 5.1E-18 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 NPD12_1779 abce82e705a6e3075c1051d660608330 289 Pfam PF01545 Cation efflux family 16 207 7.0E-46 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 NPD12_1779 abce82e705a6e3075c1051d660608330 289 Gene3D G3DSA:3.30.70.1350 210 289 7.2E-17 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 NPD12_3260 ff4de783102262ec33eb3e551fc644b4 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 2.1E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 NPD12_3260 ff4de783102262ec33eb3e551fc644b4 339 Gene3D G3DSA:3.40.50.300 1 332 1.4E-99 T 12-10-2018 NPD12_3260 ff4de783102262ec33eb3e551fc644b4 339 SMART SM00382 33 234 1.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3260 ff4de783102262ec33eb3e551fc644b4 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 321 5.7E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 NPD12_3260 ff4de783102262ec33eb3e551fc644b4 339 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3260 ff4de783102262ec33eb3e551fc644b4 339 Pfam PF00005 ABC transporter 25 184 2.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3260 ff4de783102262ec33eb3e551fc644b4 339 SUPERFAMILY SSF52540 32 322 1.62E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 Gene3D G3DSA:1.25.40.10 6 121 4.2E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 Gene3D G3DSA:1.25.40.10 122 245 5.6E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 Pfam PF13414 TPR repeat 168 204 4.6E-8 T 12-10-2018 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 SMART SM00028 90 123 34.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 SMART SM00028 56 89 6.0E-8 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 SMART SM00028 158 191 1.6E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 SMART SM00028 192 225 0.0061 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 SMART SM00028 124 157 280.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 SUPERFAMILY SSF48439 39 236 3.92E-34 T 12-10-2018 NPD12_2145 266d594e32201b8aeac2151a2b04c7af 251 Pfam PF00515 Tetratricopeptide repeat 57 89 1.5E-9 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 NPD12_2700 7682406dd6cf2efa454eb071a2888e34 173 Pfam PF03748 Flagellar basal body-associated protein FliL 79 173 1.8E-19 T 12-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 NPD12_1111 d4a60b4c2fcf36689e209483931887ed 202 Pfam PF08668 HDOD domain 27 65 2.4E-6 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD NPD12_1111 d4a60b4c2fcf36689e209483931887ed 202 SUPERFAMILY SSF109604 16 142 2.62E-12 T 12-10-2018 NPD12_1111 d4a60b4c2fcf36689e209483931887ed 202 Gene3D G3DSA:1.10.3210.10 3 178 7.6E-10 T 12-10-2018 NPD12_1111 d4a60b4c2fcf36689e209483931887ed 202 SMART SM00471 22 153 9.9E-4 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_3088 f1659f19b4bf4a518fa78be9729014f2 424 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 334 419 9.1E-13 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain NPD12_3088 f1659f19b4bf4a518fa78be9729014f2 424 Gene3D G3DSA:1.10.260.150 49 354 1.0E-80 T 12-10-2018 NPD12_3088 f1659f19b4bf4a518fa78be9729014f2 424 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 242 6.3E-40 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain NPD12_3088 f1659f19b4bf4a518fa78be9729014f2 424 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 88 241 1.1E-42 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 SUPERFAMILY SSF52317 986 1252 2.13E-72 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 7 1252 0.0 T 12-10-2018 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 Gene3D G3DSA:3.30.1330.10 650 813 2.2E-35 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 SMART SM01211 989 1252 2.4E-120 T 12-10-2018 NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 Pfam PF02769 AIR synthase related protein, C-terminal domain 442 591 1.1E-19 T 12-10-2018 IPR010918 PurM-like, C-terminal domain NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 SUPERFAMILY SSF55326 636 816 3.14E-42 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 Gene3D G3DSA:3.90.650.10 429 608 5.9E-42 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 SUPERFAMILY SSF55326 206 433 1.5E-32 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 Gene3D G3DSA:3.40.50.880 988 1253 1.6E-70 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 SUPERFAMILY SSF56042 441 607 4.78E-34 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 SUPERFAMILY SSF56042 818 958 1.64E-12 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 989 1252 8.6E-91 T 12-10-2018 NPD12_2626 de21836390fe8ddfb9868c4cc931dbac 1253 Gene3D G3DSA:3.90.650.10 815 959 2.0E-11 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 Gene3D G3DSA:3.40.50.1980 23 204 3.2E-57 T 12-10-2018 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00690 Adhesin family signature 34 52 3.9E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00690 Adhesin family signature 65 78 3.9E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00690 Adhesin family signature 202 223 3.9E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00690 Adhesin family signature 78 95 3.9E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00690 Adhesin family signature 255 273 3.9E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 Pfam PF01297 Zinc-uptake complex component A periplasmic 37 309 6.9E-73 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 SUPERFAMILY SSF53807 15 312 1.86E-85 T 12-10-2018 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 Gene3D G3DSA:3.40.50.1980 206 312 1.9E-31 T 12-10-2018 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00691 Adhesin B signature 59 77 2.2E-12 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00691 Adhesin B signature 78 97 2.2E-12 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00691 Adhesin B signature 34 55 2.2E-12 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_1629 c8709cbeae1df5ff0260ff2bcef68cd9 312 PRINTS PR00691 Adhesin B signature 290 308 2.2E-12 T 12-10-2018 IPR006129 Adhesin B GO:0007155 NPD12_272 27da5384454b08d7c365250b0114c8c7 520 SMART SM00257 471 515 1.4E-17 T 12-10-2018 IPR018392 LysM domain NPD12_272 27da5384454b08d7c365250b0114c8c7 520 Pfam PF01476 LysM domain 472 515 9.4E-17 T 12-10-2018 IPR018392 LysM domain NPD12_272 27da5384454b08d7c365250b0114c8c7 520 SUPERFAMILY SSF54106 470 515 7.98E-13 T 12-10-2018 NPD12_272 27da5384454b08d7c365250b0114c8c7 520 Gene3D G3DSA:3.10.350.10 465 519 5.1E-20 T 12-10-2018 IPR036779 LysM domain superfamily NPD12_272 27da5384454b08d7c365250b0114c8c7 520 Pfam PF12673 Domain of unknown function (DUF3794) 190 267 1.5E-9 T 12-10-2018 IPR024300 Domain of unknown function DUF3794 NPD12_272 27da5384454b08d7c365250b0114c8c7 520 Pfam PF12673 Domain of unknown function (DUF3794) 37 119 3.5E-13 T 12-10-2018 IPR024300 Domain of unknown function DUF3794 NPD12_272 27da5384454b08d7c365250b0114c8c7 520 Pfam PF12673 Domain of unknown function (DUF3794) 346 426 2.3E-18 T 12-10-2018 IPR024300 Domain of unknown function DUF3794 NPD12_2697 af34c9f699de4ca96af40576db6c3a83 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.1E-29 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 NPD12_2697 af34c9f699de4ca96af40576db6c3a83 89 PIRSF PIRSF004669 1 89 4.5E-32 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 NPD12_2697 af34c9f699de4ca96af40576db6c3a83 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 4.0E-23 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 NPD12_2697 af34c9f699de4ca96af40576db6c3a83 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 4.0E-23 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 NPD12_2697 af34c9f699de4ca96af40576db6c3a83 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 4.0E-23 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 NPD12_2697 af34c9f699de4ca96af40576db6c3a83 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 88 1.2E-29 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 SUPERFAMILY SSF51161 256 445 2.36E-47 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 Pfam PF00483 Nucleotidyl transferase 5 215 6.1E-24 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 Gene3D G3DSA:3.90.550.10 2 251 2.6E-76 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 452 2.8E-171 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 SUPERFAMILY SSF53448 2 253 4.28E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 428 7.4E-8 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 351 2.3E-6 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 299 7.0E-6 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 39.73 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 NPD12_15 f3664952d0a21bd9653fa9dfa0cdb984 457 Gene3D G3DSA:2.160.10.10 252 438 7.4E-52 T 12-10-2018 NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 SUPERFAMILY SSF51261 467 611 2.09E-49 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 Gene3D G3DSA:2.70.70.10 454 612 2.2E-50 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 SUPERFAMILY SSF55604 6 80 2.75E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 468 592 1.5E-46 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 Pfam PF02378 Phosphotransferase system, EIIC 108 385 3.9E-32 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 Pfam PF00367 phosphotransferase system, EIIB 9 41 7.0E-14 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 613 2.0E-236 T 12-10-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 469 588 1.0E-40 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_833 feae840eee5ca72fe290d33d737f6c30 613 Gene3D G3DSA:3.30.1360.60 1 77 4.8E-28 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_438 a20a9e2501fa58fdfacde779106d0a95 259 Gene3D G3DSA:3.40.50.10490 85 257 6.5E-30 T 12-10-2018 NPD12_438 a20a9e2501fa58fdfacde779106d0a95 259 SUPERFAMILY SSF53697 87 252 1.56E-24 T 12-10-2018 NPD12_438 a20a9e2501fa58fdfacde779106d0a95 259 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 75 6.0E-16 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_438 a20a9e2501fa58fdfacde779106d0a95 259 SUPERFAMILY SSF46689 7 76 1.97E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_438 a20a9e2501fa58fdfacde779106d0a95 259 Pfam PF01380 SIS domain 117 223 1.4E-11 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_438 a20a9e2501fa58fdfacde779106d0a95 259 Gene3D G3DSA:1.10.10.10 2 75 7.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Gene3D G3DSA:2.30.40.20 12 71 1.7E-28 T 12-10-2018 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Pfam PF11799 impB/mucB/samB family C-terminal domain 232 337 7.9E-18 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Gene3D G3DSA:1.10.150.20 173 226 8.1E-14 T 12-10-2018 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Gene3D G3DSA:3.30.1490.100 237 343 2.0E-29 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Gene3D G3DSA:3.30.70.270 72 162 4.0E-31 T 12-10-2018 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 SUPERFAMILY SSF56672 2 231 4.18E-85 T 12-10-2018 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 SUPERFAMILY SSF100879 235 335 1.22E-28 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Pfam PF11798 IMS family HHH motif 165 194 7.9E-7 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Pfam PF00817 impB/mucB/samB family 8 151 9.0E-48 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 NPD12_2847 af5e4175df2e364bfc38e048c66aa45a 349 Hamap MF_01113 DNA polymerase IV [dinB]. 2 346 38.109 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 NPD12_3178 bbc0cc1527f481e033cf74d32d284651 341 Pfam PF02547 Queuosine biosynthesis protein 4 340 2.2E-148 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 NPD12_3178 bbc0cc1527f481e033cf74d32d284651 341 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 47.272 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 NPD12_3178 bbc0cc1527f481e033cf74d32d284651 341 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 340 2.8E-147 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 NPD12_3178 bbc0cc1527f481e033cf74d32d284651 341 Gene3D G3DSA:3.40.1780.10 14 340 2.7E-137 T 12-10-2018 NPD12_3178 bbc0cc1527f481e033cf74d32d284651 341 Gene3D G3DSA:2.40.10.240 64 162 2.7E-137 T 12-10-2018 NPD12_3178 bbc0cc1527f481e033cf74d32d284651 341 SUPERFAMILY SSF111337 2 340 3.14E-144 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 NPD12_405 0ed5a65d824e019cc6b3ccc354a684c2 538 SUPERFAMILY SSF48317 47 535 1.31E-110 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily NPD12_405 0ed5a65d824e019cc6b3ccc354a684c2 538 Gene3D G3DSA:1.10.606.10 16 538 5.9E-180 T 12-10-2018 IPR016119 Bromoperoxidase/chloroperoxidase C-terminal GO:0004601|GO:0055114 NPD12_405 0ed5a65d824e019cc6b3ccc354a684c2 538 Pfam PF01569 PAP2 superfamily 366 514 5.8E-8 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase NPD12_2290 e8ac93521c8f490629008ce8ac6e471e 238 TIGRFAM TIGR02134 transald_staph: transaldolase 5 238 4.7E-114 T 12-10-2018 IPR011861 Transaldolase, Staphylococcus-type NPD12_2290 e8ac93521c8f490629008ce8ac6e471e 238 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 10 217 1.2E-41 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 NPD12_2290 e8ac93521c8f490629008ce8ac6e471e 238 SUPERFAMILY SSF51569 9 236 3.05E-51 T 12-10-2018 NPD12_2290 e8ac93521c8f490629008ce8ac6e471e 238 Gene3D G3DSA:3.20.20.70 1 232 2.7E-53 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1190 0559a9f53d23dfec2c5f75b8a664811c 71 Pfam PF11211 Protein of unknown function (DUF2997) 5 52 1.3E-21 T 12-10-2018 IPR021375 Protein of unknown function DUF2997 NPD12_3648 9e796364db4f5fa22727796463d737dd 123 SUPERFAMILY SSF48300 1 59 9.68E-18 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3648 9e796364db4f5fa22727796463d737dd 123 SUPERFAMILY SSF54736 52 123 4.53E-24 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like NPD12_3648 9e796364db4f5fa22727796463d737dd 123 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 123 25.146 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3648 9e796364db4f5fa22727796463d737dd 123 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 59 123 6.0E-20 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3648 9e796364db4f5fa22727796463d737dd 123 Gene3D G3DSA:1.20.5.710 1 52 4.4E-22 T 12-10-2018 NPD12_3648 9e796364db4f5fa22727796463d737dd 123 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 57 123 2.6E-29 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3648 9e796364db4f5fa22727796463d737dd 123 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 48 6.6E-22 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3648 9e796364db4f5fa22727796463d737dd 123 Gene3D G3DSA:3.30.1390.10 53 123 3.2E-30 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like NPD12_3648 9e796364db4f5fa22727796463d737dd 123 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 123 7.3E-48 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2336 598b2d05e24563b9a9f9a304cef07158 197 Pfam PF13305 WHG domain 91 175 3.0E-11 T 12-10-2018 IPR025996 WHG domain NPD12_2336 598b2d05e24563b9a9f9a304cef07158 197 SUPERFAMILY SSF48498 82 191 3.78E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily NPD12_2336 598b2d05e24563b9a9f9a304cef07158 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_2336 598b2d05e24563b9a9f9a304cef07158 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_2336 598b2d05e24563b9a9f9a304cef07158 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 2.9E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_2336 598b2d05e24563b9a9f9a304cef07158 197 SUPERFAMILY SSF46689 6 76 8.72E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2336 598b2d05e24563b9a9f9a304cef07158 197 Gene3D G3DSA:1.10.357.10 1 193 5.6E-37 T 12-10-2018 NPD12_3113 14de8d9216a171426b2830c2236fd4e8 179 Pfam PF13420 Acetyltransferase (GNAT) domain 21 158 1.2E-7 T 12-10-2018 NPD12_3113 14de8d9216a171426b2830c2236fd4e8 179 SUPERFAMILY SSF55729 9 156 1.56E-5 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_3113 14de8d9216a171426b2830c2236fd4e8 179 Gene3D G3DSA:3.40.630.30 6 170 6.9E-7 T 12-10-2018 NPD12_1971 eaaa987ad588c0a97ee9c2d7b2ba11e0 278 Gene3D G3DSA:3.60.110.10 1 276 6.8E-106 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily NPD12_1971 eaaa987ad588c0a97ee9c2d7b2ba11e0 278 Pfam PF00795 Carbon-nitrogen hydrolase 5 258 4.7E-62 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 NPD12_1971 eaaa987ad588c0a97ee9c2d7b2ba11e0 278 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 153 173 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site NPD12_1971 eaaa987ad588c0a97ee9c2d7b2ba11e0 278 SUPERFAMILY SSF56317 1 267 4.71E-80 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily NPD12_3215 a9fb7f6c2709895fdf085eab1e61c637 248 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 98 132 5.5E-8 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_3215 a9fb7f6c2709895fdf085eab1e61c637 248 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 10 43 6.9E-9 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_3215 a9fb7f6c2709895fdf085eab1e61c637 248 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 135 167 1.3E-4 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_3215 a9fb7f6c2709895fdf085eab1e61c637 248 SUPERFAMILY SSF51161 4 239 7.15E-34 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_3215 a9fb7f6c2709895fdf085eab1e61c637 248 Gene3D G3DSA:2.160.10.10 112 236 7.3E-32 T 12-10-2018 NPD12_3215 a9fb7f6c2709895fdf085eab1e61c637 248 Gene3D G3DSA:2.160.10.10 2 111 9.4E-21 T 12-10-2018 NPD12_2888 bb5ac427dab248436b8951bde143adf4 201 Gene3D G3DSA:3.20.20.80 1 200 6.5E-39 T 12-10-2018 NPD12_2888 bb5ac427dab248436b8951bde143adf4 201 SUPERFAMILY SSF51445 2 200 3.04E-42 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_2888 bb5ac427dab248436b8951bde143adf4 201 Pfam PF00232 Glycosyl hydrolase family 1 2 177 3.4E-33 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_270 0eb6e2a8cf236c34d04470d944a60592 300 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 1 288 9.0E-90 T 12-10-2018 IPR008764 Peptidase U57, YabG NPD12_270 0eb6e2a8cf236c34d04470d944a60592 300 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 3 296 2.9E-127 T 12-10-2018 IPR008764 Peptidase U57, YabG NPD12_270 0eb6e2a8cf236c34d04470d944a60592 300 PIRSF PIRSF011575 1 300 9.6E-134 T 12-10-2018 IPR008764 Peptidase U57, YabG NPD12_270 0eb6e2a8cf236c34d04470d944a60592 300 Pfam PF05582 YabG peptidase U57 3 295 4.2E-122 T 12-10-2018 IPR008764 Peptidase U57, YabG NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 SUPERFAMILY SSF46894 133 235 1.62E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 SUPERFAMILY SSF52172 4 136 3.7E-38 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 Pfam PF00072 Response regulator receiver domain 11 120 1.9E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 SMART SM00862 158 234 5.3E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 SMART SM00448 9 120 2.9E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 234 1.1E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 Gene3D G3DSA:3.40.50.2300 6 135 8.3E-34 T 12-10-2018 NPD12_1151 f9a8e2f7c3980c5bf43c29f4474f3966 240 Gene3D G3DSA:1.10.10.10 136 240 3.5E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_457 5b3d572d2686002818395f5991cc8fcd 571 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 469 480 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 NPD12_457 5b3d572d2686002818395f5991cc8fcd 571 Gene3D G3DSA:3.50.30.80 381 530 5.4E-48 T 12-10-2018 NPD12_457 5b3d572d2686002818395f5991cc8fcd 571 SUPERFAMILY SSF52016 382 570 3.53E-49 T 12-10-2018 NPD12_457 5b3d572d2686002818395f5991cc8fcd 571 SUPERFAMILY SSF143975 10 380 4.97E-121 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 NPD12_457 5b3d572d2686002818395f5991cc8fcd 571 Pfam PF00920 Dehydratase family 29 567 5.1E-184 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 SUPERFAMILY SSF52540 340 581 8.84E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 SMART SM00382 370 556 1.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 Pfam PF00664 ABC transporter transmembrane region 22 299 2.2E-47 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 Gene3D G3DSA:1.20.1560.10 1 331 1.6E-88 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 Gene3D G3DSA:3.40.50.300 341 584 2.6E-90 T 12-10-2018 NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 SUPERFAMILY SSF90123 2 328 6.15E-77 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2120 0daba6cc318af580b82f4c179b7e4520 585 Pfam PF00005 ABC transporter 361 510 1.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_57 51a7f3ce1265814cba871d370f8942a6 161 Pfam PF08761 dUTPase 2 161 2.6E-49 T 12-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 NPD12_57 51a7f3ce1265814cba871d370f8942a6 161 PIRSF PIRSF030140 1 161 5.0E-59 T 12-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 NPD12_57 51a7f3ce1265814cba871d370f8942a6 161 SUPERFAMILY SSF101386 2 161 1.18E-47 T 12-10-2018 NPD12_57 51a7f3ce1265814cba871d370f8942a6 161 Gene3D G3DSA:1.10.4010.10 1 161 4.8E-14 T 12-10-2018 NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 Gene3D G3DSA:3.30.870.10 54 224 1.1E-34 T 12-10-2018 NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 SMART SM00490 482 567 8.2E-15 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 Pfam PF00271 Helicase conserved C-terminal domain 468 566 2.7E-14 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 SUPERFAMILY SSF56024 65 209 7.22E-12 T 12-10-2018 NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 Pfam PF11907 Domain of unknown function (DUF3427) 709 986 1.7E-85 T 12-10-2018 IPR021835 Protein of unknown function DUF3427 NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 Gene3D G3DSA:3.40.50.300 225 405 3.1E-48 T 12-10-2018 NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 Gene3D G3DSA:3.40.50.300 428 588 1.6E-42 T 12-10-2018 NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 Pfam PF13091 PLD-like domain 72 202 1.0E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 SMART SM00487 238 425 9.5E-18 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 SUPERFAMILY SSF52540 288 587 8.01E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_826 ec8b288b2c41b3e41e380d3dec15d0e9 988 Pfam PF04851 Type III restriction enzyme, res subunit 240 390 1.7E-35 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 NPD12_2546 2c26a735127e47b9437b5f47bdad90d9 63 Pfam PF00830 Ribosomal L28 family 3 58 4.0E-22 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2546 2c26a735127e47b9437b5f47bdad90d9 63 Gene3D G3DSA:2.30.170.40 19 63 3.6E-20 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2546 2c26a735127e47b9437b5f47bdad90d9 63 SUPERFAMILY SSF143800 2 61 1.24E-23 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2546 2c26a735127e47b9437b5f47bdad90d9 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 5.1E-23 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2546 2c26a735127e47b9437b5f47bdad90d9 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 17.774 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 5 329 3.7E-110 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 SUPERFAMILY SSF52374 7 329 3.82E-98 T 12-10-2018 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 330 42.084 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 Gene3D G3DSA:3.40.50.620 8 328 2.2E-136 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 Pfam PF00579 tRNA synthetases class I (W and Y) 5 284 5.8E-80 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 Gene3D G3DSA:1.10.240.10 188 297 2.2E-136 T 12-10-2018 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 1.0E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 18 34 1.0E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 197 207 1.0E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 144 165 1.0E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 NPD12_3460 7575e45c79cb1b0b3e7a25ef6120f414 332 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 23 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_2331 2b6b8bc7b3a01f35e185979729d44024 445 Pfam PF07005 Putative sugar-binding N-terminal domain 5 229 1.2E-52 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain NPD12_2331 2b6b8bc7b3a01f35e185979729d44024 445 SUPERFAMILY SSF142764 5 438 1.7E-82 T 12-10-2018 NPD12_2331 2b6b8bc7b3a01f35e185979729d44024 445 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 258 429 6.4E-27 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain NPD12_2331 2b6b8bc7b3a01f35e185979729d44024 445 Gene3D G3DSA:3.40.50.10840 4 225 4.5E-57 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily NPD12_2331 2b6b8bc7b3a01f35e185979729d44024 445 Gene3D G3DSA:3.40.980.20 247 436 1.0E-12 T 12-10-2018 NPD12_3515 9824f3dd3da6489b70c19666d067bfee 208 Gene3D G3DSA:3.40.50.360 1 194 3.0E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_3515 9824f3dd3da6489b70c19666d067bfee 208 Pfam PF03358 NADPH-dependent FMN reductase 1 156 1.9E-33 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_3515 9824f3dd3da6489b70c19666d067bfee 208 SUPERFAMILY SSF52218 1 186 1.55E-44 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 3.0E-68 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 1.6E-181 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 Gene3D G3DSA:3.40.1830.10 1 180 3.0E-72 T 12-10-2018 IPR035097 Peptidase M29, N-terminal NPD12_2827 2718a82aceabcca6d4734b478d921b6c 410 SUPERFAMILY SSF144052 4 409 1.16E-151 T 12-10-2018 NPD12_693 8777e7fcdc6257f386de29729145ba35 331 SUPERFAMILY SSF52743 3 278 4.84E-27 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_693 8777e7fcdc6257f386de29729145ba35 331 Pfam PF00082 Subtilase family 36 220 2.2E-5 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 NPD12_693 8777e7fcdc6257f386de29729145ba35 331 Gene3D G3DSA:3.40.50.200 2 243 1.3E-23 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_593 53b945de780b7a1c6ede90dc9778a405 127 PIRSF PIRSF006246 1 127 8.2E-55 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 NPD12_593 53b945de780b7a1c6ede90dc9778a405 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 93 6.0E-36 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 NPD12_593 53b945de780b7a1c6ede90dc9778a405 127 SUPERFAMILY SSF50692 1 122 1.07E-50 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily NPD12_593 53b945de780b7a1c6ede90dc9778a405 127 Pfam PF02261 Aspartate decarboxylase 1 114 9.4E-55 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 NPD12_593 53b945de780b7a1c6ede90dc9778a405 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 3.4E-50 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 NPD12_593 53b945de780b7a1c6ede90dc9778a405 127 Gene3D G3DSA:2.40.40.20 1 123 3.8E-55 T 12-10-2018 NPD12_593 53b945de780b7a1c6ede90dc9778a405 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 70.386 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 NPD12_2619 eae9efae2a7fa7bc0ace16e0f3339ca4 288 Gene3D G3DSA:2.20.28.50 28 64 2.9E-45 T 12-10-2018 NPD12_2619 eae9efae2a7fa7bc0ace16e0f3339ca4 288 Gene3D G3DSA:3.30.1180.10 158 288 1.7E-40 T 12-10-2018 NPD12_2619 eae9efae2a7fa7bc0ace16e0f3339ca4 288 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 285 1.6E-82 T 12-10-2018 IPR003797 DegV NPD12_2619 eae9efae2a7fa7bc0ace16e0f3339ca4 288 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 283 3.8E-93 T 12-10-2018 IPR003797 DegV NPD12_2619 eae9efae2a7fa7bc0ace16e0f3339ca4 288 Gene3D G3DSA:3.40.50.10440 5 147 2.9E-45 T 12-10-2018 NPD12_2619 eae9efae2a7fa7bc0ace16e0f3339ca4 288 SUPERFAMILY SSF82549 4 285 1.1E-82 T 12-10-2018 NPD12_3151 8adc36f53d93550ae56ab47993111178 69 SMART SM00530 6 61 7.6E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3151 8adc36f53d93550ae56ab47993111178 69 SUPERFAMILY SSF47413 2 63 2.14E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3151 8adc36f53d93550ae56ab47993111178 69 Gene3D G3DSA:1.10.260.40 1 69 2.3E-13 T 12-10-2018 NPD12_3151 8adc36f53d93550ae56ab47993111178 69 Pfam PF01381 Helix-turn-helix 7 61 4.6E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2835 d536edc4335ec993a061570f36119cb7 130 Gene3D G3DSA:1.20.120.20 27 130 3.4E-8 T 12-10-2018 NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 SUPERFAMILY SSF56281 22 437 4.06E-98 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 Pfam PF00753 Metallo-beta-lactamase superfamily 35 178 4.4E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 378 406 - T 12-10-2018 IPR001587 Ribonuclease J, conserved site NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 PIRSF PIRSF004803 13 569 8.1E-246 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 368 417 5.8E-10 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 Gene3D G3DSA:3.10.20.580 463 569 2.5E-39 T 12-10-2018 NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 Gene3D G3DSA:3.40.50.10710 221 371 6.0E-189 T 12-10-2018 NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 Hamap MF_01491 Ribonuclease J [rnj]. 17 569 48.414 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 Gene3D G3DSA:3.60.15.10 25 456 6.0E-189 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 SMART SM00849 34 229 5.9E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2605 636cbc00a96365d849a92c54ec173e01 569 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 22 567 3.8E-205 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 NPD12_1596 c1893d7c2369ce46535347e022b00412 365 SUPERFAMILY SSF55874 215 359 4.06E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1596 c1893d7c2369ce46535347e022b00412 365 SMART SM00387 254 362 2.3E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1596 c1893d7c2369ce46535347e022b00412 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 359 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1596 c1893d7c2369ce46535347e022b00412 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 340 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1596 c1893d7c2369ce46535347e022b00412 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1596 c1893d7c2369ce46535347e022b00412 365 Gene3D G3DSA:3.30.565.10 212 357 5.0E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1596 c1893d7c2369ce46535347e022b00412 365 Gene3D G3DSA:1.10.287.130 179 211 5.0E-34 T 12-10-2018 NPD12_1596 c1893d7c2369ce46535347e022b00412 365 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 358 2.2E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 Gene3D G3DSA:3.40.630.10 3 241 3.6E-59 T 12-10-2018 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PIRSF PIRSF016599 2 487 2.6E-173 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 Gene3D G3DSA:3.40.630.10 363 486 3.8E-23 T 12-10-2018 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 Pfam PF07687 Peptidase dimerisation domain 213 290 3.7E-5 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 SUPERFAMILY SSF53187 12 484 2.62E-53 T 12-10-2018 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 Pfam PF01546 Peptidase family M20/M25/M40 73 482 6.5E-16 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 11 484 5.4E-172 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 207 224 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 160 178 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 102 120 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 252 271 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 81 100 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 430 446 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 452 474 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_1651 34495d2b62efdcce0ff7f144ccab7fea 487 PRINTS PR00934 X-His dipeptidase (M25) signature 136 153 4.6E-48 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 Gene3D G3DSA:3.90.1310.20 59 556 9.2E-176 T 12-10-2018 NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 Gene3D G3DSA:1.10.3810.10 75 278 9.2E-176 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 Gene3D G3DSA:3.40.710.10 327 655 9.2E-176 T 12-10-2018 NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 75 645 1.8E-166 T 12-10-2018 NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 SUPERFAMILY SSF53955 53 264 3.09E-65 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 Pfam PF00912 Transglycosylase 67 248 4.4E-57 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 Pfam PF00905 Penicillin binding protein transpeptidase domain 358 619 3.3E-26 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 NPD12_3192 3851b01cf37126ac641ede80b9722ae3 827 SUPERFAMILY SSF56601 232 717 3.02E-98 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_2734 f1f6e10569472509bc9b4252dd64adee 225 Pfam PF02397 Bacterial sugar transferase 31 219 1.9E-66 T 12-10-2018 IPR003362 Bacterial sugar transferase NPD12_1125 9e1d3b4c79ec8f21fef697c385c143f8 191 Pfam PF13847 Methyltransferase domain 32 148 1.6E-12 T 12-10-2018 IPR025714 Methyltransferase domain NPD12_1125 9e1d3b4c79ec8f21fef697c385c143f8 191 SUPERFAMILY SSF53335 11 159 7.77E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_1125 9e1d3b4c79ec8f21fef697c385c143f8 191 Gene3D G3DSA:3.40.50.150 2 190 5.1E-61 T 12-10-2018 NPD12_1125 9e1d3b4c79ec8f21fef697c385c143f8 191 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 37 66 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 NPD12_1125 9e1d3b4c79ec8f21fef697c385c143f8 191 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 15 138 3.2E-37 T 12-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 NPD12_2056 ba3ec3a5dc47c07ad6b3c617f5469c45 196 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 108 3.3E-38 T 12-10-2018 IPR014245 Sporulation stage III, protein AF NPD12_2056 ba3ec3a5dc47c07ad6b3c617f5469c45 196 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 14 193 5.5E-39 T 12-10-2018 IPR014245 Sporulation stage III, protein AF NPD12_2939 b2035a1fe66c1942153a796a28e5463b 468 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 353 373 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 NPD12_2939 b2035a1fe66c1942153a796a28e5463b 468 TIGRFAM TIGR03173 pbuX: xanthine permease 24 438 7.0E-163 T 12-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 NPD12_2939 b2035a1fe66c1942153a796a28e5463b 468 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 18 435 4.8E-114 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 NPD12_2939 b2035a1fe66c1942153a796a28e5463b 468 Pfam PF00860 Permease family 20 405 6.8E-102 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 NPD12_1715 560b9f04d0f38a60915378a58fe5737b 223 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 14 218 4.2E-66 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 NPD12_1715 560b9f04d0f38a60915378a58fe5737b 223 SUPERFAMILY SSF51419 3 216 3.66E-71 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_1715 560b9f04d0f38a60915378a58fe5737b 223 Gene3D G3DSA:3.20.20.10 1 222 6.5E-78 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_1715 560b9f04d0f38a60915378a58fe5737b 223 Pfam PF01168 Alanine racemase, N-terminal domain 3 218 3.7E-24 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_1715 560b9f04d0f38a60915378a58fe5737b 223 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 217 29.001 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 NPD12_1715 560b9f04d0f38a60915378a58fe5737b 223 PIRSF PIRSF004848 1 223 7.2E-78 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 Gene3D G3DSA:1.10.10.10 154 273 4.2E-54 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 163 271 4.0E-56 T 12-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 SMART SM00448 6 121 2.8E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 5 272 1.1E-132 T 12-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 SUPERFAMILY SSF46894 157 271 5.02E-50 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 PIRSF PIRSF002937 1 273 4.8E-139 T 12-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 SUPERFAMILY SSF52172 5 138 8.82E-34 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 163 266 2.2E-47 T 12-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 Pfam PF00072 Response regulator receiver domain 8 121 2.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2038 bf5ca428cf0cae6124843eafb7634fdb 273 Gene3D G3DSA:3.40.50.2300 1 136 7.7E-33 T 12-10-2018 NPD12_694 50e4e7a035342db294fae83a154679da 569 Gene3D G3DSA:3.40.50.300 323 569 8.7E-78 T 12-10-2018 NPD12_694 50e4e7a035342db294fae83a154679da 569 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_694 50e4e7a035342db294fae83a154679da 569 SMART SM00382 360 561 2.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_694 50e4e7a035342db294fae83a154679da 569 SUPERFAMILY SSF90123 10 316 4.45E-52 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_694 50e4e7a035342db294fae83a154679da 569 Pfam PF00005 ABC transporter 351 500 7.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_694 50e4e7a035342db294fae83a154679da 569 SUPERFAMILY SSF52540 325 568 1.15E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_694 50e4e7a035342db294fae83a154679da 569 Gene3D G3DSA:1.20.1560.10 2 322 3.4E-51 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_694 50e4e7a035342db294fae83a154679da 569 Pfam PF00664 ABC transporter transmembrane region 24 291 2.7E-23 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2489 eaf26bb145e623ba4cf186a5ba523e86 269 Hamap MF_00052_B Ribonuclease HII [rnhB]. 84 267 33.92 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 NPD12_2489 eaf26bb145e623ba4cf186a5ba523e86 269 Gene3D G3DSA:3.30.420.10 61 269 4.9E-69 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_2489 eaf26bb145e623ba4cf186a5ba523e86 269 Pfam PF01351 Ribonuclease HII 86 266 2.7E-38 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain NPD12_2489 eaf26bb145e623ba4cf186a5ba523e86 269 SUPERFAMILY SSF53098 74 265 1.97E-59 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_386 90fd98ea271944e7e3f511873dd2bbb8 248 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_386 90fd98ea271944e7e3f511873dd2bbb8 248 Pfam PF00121 Triosephosphate isomerase 5 246 2.1E-95 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_386 90fd98ea271944e7e3f511873dd2bbb8 248 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 62.874 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_386 90fd98ea271944e7e3f511873dd2bbb8 248 SUPERFAMILY SSF51351 1 247 4.32E-99 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_386 90fd98ea271944e7e3f511873dd2bbb8 248 Gene3D G3DSA:3.20.20.70 1 248 4.9E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_386 90fd98ea271944e7e3f511873dd2bbb8 248 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.4E-59 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 61 72 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 Pfam PF01820 D-ala D-ala ligase N-terminus 2 84 1.2E-21 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 Gene3D G3DSA:3.40.50.20 1 82 2.6E-30 T 12-10-2018 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 296 35.126 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 Gene3D G3DSA:3.30.470.20 83 292 1.1E-69 T 12-10-2018 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 239 266 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 SUPERFAMILY SSF56059 94 292 4.38E-48 T 12-10-2018 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 SUPERFAMILY SSF52440 1 94 1.73E-29 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 PIRSF PIRSF039102 42 300 1.9E-91 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 PIRSF PIRSF039102 1 51 1.7E-10 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 Pfam PF07478 D-ala D-ala ligase C-terminus 102 292 2.0E-48 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 Gene3D G3DSA:3.30.1490.20 109 175 1.1E-69 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 SMART SM01209 93 263 0.0034 T 12-10-2018 NPD12_620 c729b1d6db81aa458fc296386f52dcf9 300 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 294 1.0E-91 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 SUPERFAMILY SSF53633 5 279 4.45E-57 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 SUPERFAMILY SSF55021 288 381 3.27E-14 T 12-10-2018 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 4 438 4.4E-75 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 SUPERFAMILY SSF55021 365 438 3.6E-18 T 12-10-2018 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 Gene3D G3DSA:3.30.2130.10 280 439 1.5E-58 T 12-10-2018 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 PIRSF PIRSF000726 2 439 8.2E-74 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 Pfam PF00696 Amino acid kinase family 3 265 3.5E-32 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 NPD12_1879 3d2bcb41f55e8b750ab14970571e493a 439 Gene3D G3DSA:3.40.1160.10 2 279 7.0E-83 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 Pfam PF01880 Desulfoferrodoxin 42 123 1.0E-21 T 12-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 5 37 4.0E-18 T 12-10-2018 IPR004462 Desulforodoxin domain GO:0005506 NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 2 34 2.5E-17 T 12-10-2018 IPR004462 Desulforodoxin domain GO:0005506 NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 SUPERFAMILY SSF57802 3 37 2.9E-12 T 12-10-2018 NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 SUPERFAMILY SSF49367 40 123 1.96E-33 T 12-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 41 123 1.5E-24 T 12-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 Gene3D G3DSA:2.20.28.100 1 39 1.1E-16 T 12-10-2018 IPR038094 Desulforodoxin domain superfamily NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 Gene3D G3DSA:2.60.40.730 40 124 2.1E-33 T 12-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 NPD12_3461 94ba59f5b5a916c62eff88b5544e5a0e 124 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 2 123 3.7E-60 T 12-10-2018 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 SUPERFAMILY SSF51011 539 687 3.24E-22 T 12-10-2018 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Gene3D G3DSA:1.10.10.60 172 220 9.1E-10 T 12-10-2018 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 225 267 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Pfam PF07883 Cupin domain 23 75 6.7E-7 T 12-10-2018 IPR013096 Cupin 2, conserved barrel NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Gene3D G3DSA:2.60.120.10 4 85 3.2E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Gene3D G3DSA:3.20.20.80 330 468 3.2E-12 T 12-10-2018 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Pfam PF01229 Glycosyl hydrolases family 39 481 659 4.5E-9 T 12-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 255 1.7E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 255 271 1.7E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 SUPERFAMILY SSF51182 23 98 1.51E-10 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Gene3D G3DSA:1.10.10.60 221 278 7.2E-20 T 12-10-2018 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Pfam PF12833 Helix-turn-helix domain 195 272 7.4E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 SUPERFAMILY SSF51445 331 551 2.99E-12 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 SMART SM00342 188 271 6.5E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 Gene3D G3DSA:2.60.40.1500 534 686 9.4E-27 T 12-10-2018 NPD12_2815 d9493b3ecf0b31004989657e95525b36 688 SUPERFAMILY SSF46689 225 275 1.39E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_480 9da3d3348c74db8ffdb2f25015ed3599 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 346 366 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 NPD12_480 9da3d3348c74db8ffdb2f25015ed3599 433 Pfam PF00860 Permease family 23 398 2.6E-95 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 NPD12_480 9da3d3348c74db8ffdb2f25015ed3599 433 TIGRFAM TIGR03173 pbuX: xanthine permease 26 430 1.5E-147 T 12-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 NPD12_480 9da3d3348c74db8ffdb2f25015ed3599 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 428 8.3E-120 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 137 2.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 198 217 2.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 186 2.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 SUPERFAMILY SSF51735 49 291 6.22E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 236 9.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 188 9.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 137 9.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 51 68 9.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 253 273 9.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 217 9.2E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 59 289 2.1E-59 T 12-10-2018 NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 Gene3D G3DSA:3.40.50.720 6 292 1.6E-83 T 12-10-2018 NPD12_1903 b8f598a43fb6121c3706d84bd86ae726 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 185 213 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 NPD12_3590 378dcbdb22f11eb3fdc62f4e26cc4a67 177 Gene3D G3DSA:2.40.10.420 138 175 4.7E-13 T 12-10-2018 NPD12_3590 378dcbdb22f11eb3fdc62f4e26cc4a67 177 Pfam PF07486 Cell Wall Hydrolase 74 174 7.0E-27 T 12-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 NPD12_3590 378dcbdb22f11eb3fdc62f4e26cc4a67 177 Gene3D G3DSA:1.10.10.2520 57 137 8.3E-26 T 12-10-2018 NPD12_451 345a3b03ace8e40cca4c3b4ca6521cc8 201 SUPERFAMILY SSF52833 1 196 2.65E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_451 345a3b03ace8e40cca4c3b4ca6521cc8 201 Gene3D G3DSA:3.40.30.10 1 196 1.2E-38 T 12-10-2018 NPD12_451 345a3b03ace8e40cca4c3b4ca6521cc8 201 Pfam PF01323 DSBA-like thioredoxin domain 5 193 2.3E-34 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 NPD12_2572 0539f7899a19d714840e0ac9d9a57604 307 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 26 305 7.2E-88 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 NPD12_2572 0539f7899a19d714840e0ac9d9a57604 307 SUPERFAMILY SSF161098 39 297 5.51E-35 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2572 0539f7899a19d714840e0ac9d9a57604 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 305 1.8E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_2572 0539f7899a19d714840e0ac9d9a57604 307 Gene3D G3DSA:1.10.3720.10 83 306 4.2E-34 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2312 5f385db08259411e2c58a23874175324 257 Gene3D G3DSA:3.30.420.40 4 252 1.7E-88 T 12-10-2018 NPD12_2312 5f385db08259411e2c58a23874175324 257 SUPERFAMILY SSF53067 2 252 6.26E-42 T 12-10-2018 NPD12_2312 5f385db08259411e2c58a23874175324 257 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 2 250 9.4E-84 T 12-10-2018 IPR008275 CoA enzyme activase NPD12_2312 5f385db08259411e2c58a23874175324 257 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 252 3.3E-63 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_2312 5f385db08259411e2c58a23874175324 257 Gene3D G3DSA:3.30.420.40 95 237 1.7E-88 T 12-10-2018 NPD12_2463 22b75e49a6f2b33f427049839a6daff8 289 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 209 1.8E-80 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2463 22b75e49a6f2b33f427049839a6daff8 289 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 171 225 5.3E-12 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 NPD12_2463 22b75e49a6f2b33f427049839a6daff8 289 SUPERFAMILY SSF55120 1 225 5.18E-84 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2463 22b75e49a6f2b33f427049839a6daff8 289 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 288 19.154 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2463 22b75e49a6f2b33f427049839a6daff8 289 Gene3D G3DSA:3.30.2350.10 1 235 8.7E-95 T 12-10-2018 NPD12_2463 22b75e49a6f2b33f427049839a6daff8 289 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 170 4.3E-61 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 NPD12_1665 69b48db64646e1eadaf4a97d3361b744 272 Gene3D G3DSA:3.40.190.10 126 227 3.1E-61 T 12-10-2018 NPD12_1665 69b48db64646e1eadaf4a97d3361b744 272 SUPERFAMILY SSF53850 6 267 8.76E-59 T 12-10-2018 NPD12_1665 69b48db64646e1eadaf4a97d3361b744 272 SMART SM00062 44 267 1.8E-52 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_1665 69b48db64646e1eadaf4a97d3361b744 272 Gene3D G3DSA:3.40.190.10 48 264 3.1E-61 T 12-10-2018 NPD12_1665 69b48db64646e1eadaf4a97d3361b744 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 265 2.7E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_3169 fbc814425984658d7dbf8cdbc206f18c 172 Gene3D G3DSA:3.40.50.2020 1 171 6.4E-65 T 12-10-2018 NPD12_3169 fbc814425984658d7dbf8cdbc206f18c 172 SUPERFAMILY SSF53271 2 171 1.7E-52 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_3169 fbc814425984658d7dbf8cdbc206f18c 172 Pfam PF00156 Phosphoribosyl transferase domain 36 148 1.2E-16 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_3169 fbc814425984658d7dbf8cdbc206f18c 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.904 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 NPD12_3169 fbc814425984658d7dbf8cdbc206f18c 172 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 1.3E-72 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 SUPERFAMILY SSF52738 170 352 1.14E-60 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 Gene3D G3DSA:3.40.50.180 164 354 2.5E-66 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 SMART SM00448 4 128 1.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 Pfam PF00072 Response regulator receiver domain 6 112 4.7E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 SUPERFAMILY SSF52172 2 111 3.7E-29 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 354 37.018 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 PIRSF PIRSF000876 1 354 6.2E-126 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 Gene3D G3DSA:3.40.50.2300 2 142 2.7E-33 T 12-10-2018 NPD12_2783 ebd182d9dd67794ae0b7acd68234ae44 354 Pfam PF01339 CheB methylesterase 174 349 6.7E-59 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 382 567 7.5E-31 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 Pfam PF07700 Haem-NO-binding 2 158 9.8E-43 T 12-10-2018 IPR011644 Heme NO-binding GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 SUPERFAMILY SSF58104 299 596 3.53E-57 T 12-10-2018 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 Gene3D G3DSA:1.10.287.950 251 585 8.7E-54 T 12-10-2018 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 SUPERFAMILY SSF111126 1 181 7.32E-45 T 12-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 SMART SM00283 322 583 1.3E-35 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 Gene3D G3DSA:3.90.1520.10 1 183 3.2E-60 T 12-10-2018 IPR038158 H-NOX domain superfamily GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 336 365 5.9E-5 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_29 3d50f17aad77e6c96de51a6f33ffc054 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 449 478 5.9E-5 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_624 6f37d32d256ed932abbe7ddc7b4a2e96 245 Pfam PF00005 ABC transporter 20 167 5.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_624 6f37d32d256ed932abbe7ddc7b4a2e96 245 SUPERFAMILY SSF52540 3 239 1.17E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_624 6f37d32d256ed932abbe7ddc7b4a2e96 245 Gene3D G3DSA:3.40.50.300 1 241 2.7E-63 T 12-10-2018 NPD12_624 6f37d32d256ed932abbe7ddc7b4a2e96 245 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 217 239 9.9E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal NPD12_624 6f37d32d256ed932abbe7ddc7b4a2e96 245 SMART SM00382 28 216 2.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3188 af0511c828db4f1bceba4bc1690e2361 52 SUPERFAMILY SSF57802 1 51 3.7E-23 T 12-10-2018 NPD12_3188 af0511c828db4f1bceba4bc1690e2361 52 PIRSF PIRSF000071 1 52 7.7E-27 T 12-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 NPD12_3188 af0511c828db4f1bceba4bc1690e2361 52 Gene3D G3DSA:2.20.28.10 1 52 1.4E-27 T 12-10-2018 NPD12_3188 af0511c828db4f1bceba4bc1690e2361 52 Pfam PF00301 Rubredoxin 3 49 1.3E-24 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 NPD12_3188 af0511c828db4f1bceba4bc1690e2361 52 PRINTS PR00163 Rubredoxin signature 33 49 4.3E-12 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 NPD12_3188 af0511c828db4f1bceba4bc1690e2361 52 PRINTS PR00163 Rubredoxin signature 3 19 4.3E-12 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 NPD12_3188 af0511c828db4f1bceba4bc1690e2361 52 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 12-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 NPD12_2165 c288c5fd9b7b14ff59adddf4abda3c15 181 SUPERFAMILY SSF53271 14 168 2.17E-21 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_2165 c288c5fd9b7b14ff59adddf4abda3c15 181 Gene3D G3DSA:3.40.50.2020 2 178 3.6E-46 T 12-10-2018 NPD12_2165 c288c5fd9b7b14ff59adddf4abda3c15 181 Pfam PF00156 Phosphoribosyl transferase domain 51 159 5.0E-12 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_1832 5de00d42423f959fe025ebe38c201493 402 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 62 399 9.3E-108 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase NPD12_1832 5de00d42423f959fe025ebe38c201493 402 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 119 338 5.6E-47 T 12-10-2018 IPR000477 Reverse transcriptase domain NPD12_1832 5de00d42423f959fe025ebe38c201493 402 SUPERFAMILY SSF56672 96 353 2.09E-48 T 12-10-2018 NPD12_1832 5de00d42423f959fe025ebe38c201493 402 Pfam PF13655 N-terminal domain of reverse transcriptase 19 98 1.3E-26 T 12-10-2018 IPR025960 Reverse transcriptase, N-terminal domain NPD12_1832 5de00d42423f959fe025ebe38c201493 402 Pfam PF08388 Group II intron, maturase-specific domain 358 398 1.4E-6 T 12-10-2018 IPR013597 Group II intron, maturase-specific NPD12_1832 5de00d42423f959fe025ebe38c201493 402 Gene3D G3DSA:3.30.70.270 268 345 1.6E-5 T 12-10-2018 NPD12_803 fe659f74311abbdea81391cd34d42142 246 Pfam PF04397 LytTr DNA-binding domain 147 244 1.2E-23 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_803 fe659f74311abbdea81391cd34d42142 246 SMART SM00850 146 245 2.4E-29 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_803 fe659f74311abbdea81391cd34d42142 246 Gene3D G3DSA:2.40.50.1020 145 246 8.0E-13 T 12-10-2018 NPD12_803 fe659f74311abbdea81391cd34d42142 246 SUPERFAMILY SSF52540 13 121 1.64E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_803 fe659f74311abbdea81391cd34d42142 246 Gene3D G3DSA:3.40.50.300 3 144 4.0E-12 T 12-10-2018 NPD12_1614 61e3c3ec46d4a298022aeab5ff705a25 202 Pfam PF06475 Putative glycolipid-binding 14 194 8.4E-57 T 12-10-2018 IPR009467 Putative glycolipid-binding protein NPD12_1614 61e3c3ec46d4a298022aeab5ff705a25 202 SUPERFAMILY SSF159275 12 195 1.01E-55 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Pfam PF00702 haloacid dehalogenase-like hydrolase 321 623 1.0E-24 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 467 485 1.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 666 1.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 1.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 609 625 1.9E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 SUPERFAMILY SSF81653 113 224 3.92E-33 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Pfam PF00689 Cation transporting ATPase, C-terminus 693 862 8.4E-41 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 SMART SM00831 3 76 1.3E-18 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Gene3D G3DSA:3.40.50.1000 321 654 9.9E-283 T 12-10-2018 IPR023214 HAD superfamily NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Gene3D G3DSA:3.40.1110.10 334 514 9.9E-283 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 SUPERFAMILY SSF81660 330 518 1.22E-49 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 SUPERFAMILY SSF56784 322 714 2.42E-60 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Gene3D G3DSA:1.20.1110.10 54 858 9.9E-283 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Gene3D G3DSA:2.70.150.10 19 227 9.9E-283 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 628 3.2E-39 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 645 3.2E-39 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 3.2E-39 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 518 3.2E-39 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 3.2E-39 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 3.2E-39 T 12-10-2018 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 SUPERFAMILY SSF81665 2 865 3.01E-115 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 347 2.1E-45 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 580 700 6.4E-33 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 71 1.0E-17 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_1784 a82cc34f68fe07fa94b354f0b9baca46 878 Pfam PF00122 E1-E2 ATPase 110 303 2.1E-59 T 12-10-2018 NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 SUPERFAMILY SSF54999 5 102 9.16E-38 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 SMART SM01403 7 101 4.4E-57 T 12-10-2018 IPR027486 Ribosomal protein S10 domain NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 Gene3D G3DSA:3.30.70.600 1 102 9.2E-38 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.3E-45 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 8.8E-35 T 12-10-2018 IPR027486 Ribosomal protein S10 domain NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.3E-19 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.3E-19 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.3E-19 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3640 bcf3b02927b249e48e3ad930c34eb497 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.709 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1666 63e803e1e4d7222ca28eddfc1fb5180d 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 218 1.9E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1666 63e803e1e4d7222ca28eddfc1fb5180d 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 112 5.9E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 NPD12_1666 63e803e1e4d7222ca28eddfc1fb5180d 221 SUPERFAMILY SSF161098 13 203 7.19E-43 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1666 63e803e1e4d7222ca28eddfc1fb5180d 221 Gene3D G3DSA:1.10.3720.10 2 219 1.7E-50 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 SUPERFAMILY SSF51338 19 377 2.26E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 Pfam PF13382 Adenine deaminase C-terminal domain 426 591 4.7E-68 T 12-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 Gene3D G3DSA:3.20.20.140 84 331 5.4E-127 T 12-10-2018 NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 SUPERFAMILY SSF51556 84 334 1.8E-17 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 Gene3D G3DSA:2.30.40.10 20 369 5.4E-127 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 TIGRFAM TIGR01178 ade: adenine deaminase 28 595 1.4E-168 T 12-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 Pfam PF01979 Amidohydrolase family 80 368 4.5E-20 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 NPD12_460 f6c2c6a437399fdcf91ee89144f88cda 599 Hamap MF_01518 Adenine deaminase [ade]. 28 594 36.605 T 12-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 NPD12_1412 0ede6eb4ca3e6883ab6938cbc42cdce2 224 Gene3D G3DSA:3.40.50.300 1 224 6.4E-70 T 12-10-2018 NPD12_1412 0ede6eb4ca3e6883ab6938cbc42cdce2 224 SUPERFAMILY SSF52540 3 222 3.31E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1412 0ede6eb4ca3e6883ab6938cbc42cdce2 224 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1412 0ede6eb4ca3e6883ab6938cbc42cdce2 224 SMART SM00382 32 220 3.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1412 0ede6eb4ca3e6883ab6938cbc42cdce2 224 Pfam PF00005 ABC transporter 23 171 3.5E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1912 9fa7823c1e725a2ae943b9b47ac748ab 273 SUPERFAMILY SSF161098 67 262 1.13E-24 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1912 9fa7823c1e725a2ae943b9b47ac748ab 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 265 9.9E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1912 9fa7823c1e725a2ae943b9b47ac748ab 273 Gene3D G3DSA:1.10.3720.10 70 272 2.1E-19 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2897 c791458cedc8201cc92156aa1c4c2b77 344 Pfam PF04055 Radical SAM superfamily 107 265 7.9E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2897 c791458cedc8201cc92156aa1c4c2b77 344 PIRSF PIRSF006004 2 343 9.1E-100 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 NPD12_2897 c791458cedc8201cc92156aa1c4c2b77 344 Gene3D G3DSA:3.20.20.70 66 329 5.3E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2897 c791458cedc8201cc92156aa1c4c2b77 344 TIGRFAM TIGR04432 rSAM_Cfr: 23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr 4 340 3.1E-188 T 12-10-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 MetaCyc: PWY-6828 NPD12_2897 c791458cedc8201cc92156aa1c4c2b77 344 Gene3D G3DSA:1.10.150.530 4 58 1.1E-6 T 12-10-2018 NPD12_2897 c791458cedc8201cc92156aa1c4c2b77 344 Hamap MF_01873 Ribosomal RNA large subunit methyltransferase Cfr [cfr]. 2 344 66.577 T 12-10-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 MetaCyc: PWY-6828 NPD12_2897 c791458cedc8201cc92156aa1c4c2b77 344 SUPERFAMILY SSF102114 105 311 4.19E-10 T 12-10-2018 NPD12_1604 a8483d1187346be30b2d6a0ce3b2deca 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 NPD12_1604 a8483d1187346be30b2d6a0ce3b2deca 399 SUPERFAMILY SSF103473 1 386 6.8E-54 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_1604 a8483d1187346be30b2d6a0ce3b2deca 399 Pfam PF07690 Major Facilitator Superfamily 20 189 1.0E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_1604 a8483d1187346be30b2d6a0ce3b2deca 399 Pfam PF07690 Major Facilitator Superfamily 220 385 7.3E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_1604 a8483d1187346be30b2d6a0ce3b2deca 399 Gene3D G3DSA:1.20.1250.20 4 200 1.7E-25 T 12-10-2018 NPD12_1604 a8483d1187346be30b2d6a0ce3b2deca 399 Gene3D G3DSA:1.20.1250.20 205 391 1.5E-19 T 12-10-2018 NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 SUPERFAMILY SSF46785 1 112 2.01E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.8E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.8E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.8E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 Pfam PF03466 LysR substrate binding domain 91 294 2.9E-31 T 12-10-2018 IPR005119 LysR, substrate-binding NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 Gene3D G3DSA:1.10.10.10 2 90 3.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 SUPERFAMILY SSF53850 92 294 1.06E-30 T 12-10-2018 NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 Gene3D G3DSA:3.40.190.10 167 269 5.5E-35 T 12-10-2018 NPD12_1046 28e4a7e1161e7a25f831427b556e9dda 295 Gene3D G3DSA:3.40.190.10 92 293 5.5E-35 T 12-10-2018 NPD12_2227 cf7baa6a8a76edc27299343add3ad511 682 Gene3D G3DSA:3.40.50.300 3 169 1.2E-5 T 12-10-2018 NPD12_2227 cf7baa6a8a76edc27299343add3ad511 682 SUPERFAMILY SSF52540 42 551 1.92E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2227 cf7baa6a8a76edc27299343add3ad511 682 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 449 526 6.4E-9 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_2227 cf7baa6a8a76edc27299343add3ad511 682 Gene3D G3DSA:3.40.50.300 329 544 4.3E-10 T 12-10-2018 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 SMART SM00387 345 457 1.2E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1826 a7ae373d172428bba52fb323b424f599 459 SMART SM00388 235 300 6.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 455 8.1E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1826 a7ae373d172428bba52fb323b424f599 459 SUPERFAMILY SSF47384 220 296 7.65E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 296 1.4E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 SUPERFAMILY SSF55874 305 455 5.24E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1826 a7ae373d172428bba52fb323b424f599 459 Gene3D G3DSA:1.10.287.130 207 297 2.6E-15 T 12-10-2018 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 Gene3D G3DSA:3.30.565.10 304 456 1.3E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1826 a7ae373d172428bba52fb323b424f599 459 PRINTS PR01780 Lantibiotic regulatory protein signature 244 260 9.2E-10 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 PRINTS PR01780 Lantibiotic regulatory protein signature 207 221 9.2E-10 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 PRINTS PR01780 Lantibiotic regulatory protein signature 384 400 9.2E-10 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 NPD12_1826 a7ae373d172428bba52fb323b424f599 459 PRINTS PR01780 Lantibiotic regulatory protein signature 341 356 9.2E-10 T 12-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 TIGRFAM TIGR01056 topB: DNA topoisomerase III 4 729 9.8E-249 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 SMART SM00493 3 126 2.3E-15 T 12-10-2018 IPR006171 TOPRIM domain NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 298 313 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 3.9E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 386 402 3.9E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 514 528 3.9E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 304 313 3.9E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 3.9E-28 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 Pfam PF01751 Toprim domain 4 133 1.4E-13 T 12-10-2018 IPR006171 TOPRIM domain NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 Gene3D G3DSA:2.70.20.10 210 480 2.6E-154 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 640 61.036 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 Gene3D G3DSA:1.10.290.10 270 400 2.6E-154 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 Gene3D G3DSA:1.10.460.10 160 595 2.6E-154 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 SMART SM00437 261 551 1.1E-89 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 Gene3D G3DSA:3.40.50.140 4 154 1.3E-51 T 12-10-2018 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 SUPERFAMILY SSF56712 3 601 7.98E-181 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 SMART SM00436 126 216 5.7E-41 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 NPD12_1538 8ffab14d9068308b3097aa69b690a1b5 731 Pfam PF01131 DNA topoisomerase 152 584 1.8E-128 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 NPD12_2073 68e3324ba52a55760c891f911455ad95 134 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site NPD12_2073 68e3324ba52a55760c891f911455ad95 134 SUPERFAMILY SSF54523 14 121 1.8E-15 T 12-10-2018 NPD12_2073 68e3324ba52a55760c891f911455ad95 134 Gene3D G3DSA:3.30.700.10 14 134 7.5E-19 T 12-10-2018 NPD12_2073 68e3324ba52a55760c891f911455ad95 134 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 33 2.2E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site NPD12_2073 68e3324ba52a55760c891f911455ad95 134 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 5.6E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 365 5.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 322 5.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 347 5.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 Gene3D G3DSA:1.10.287.130 137 212 3.0E-19 T 12-10-2018 NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 SUPERFAMILY SSF55874 201 366 3.67E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 Pfam PF00512 His Kinase A (phospho-acceptor) domain 145 210 7.2E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 SMART SM00387 257 368 1.1E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 258 366 1.6E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 Gene3D G3DSA:3.30.565.10 213 371 2.8E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 SUPERFAMILY SSF47384 134 211 1.63E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_788 66a375523b98f451ef8172ae58cc2da5 373 SMART SM00388 144 211 5.0E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 SUPERFAMILY SSF102114 94 416 4.45E-62 T 12-10-2018 NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 Pfam PF04055 Radical SAM superfamily 101 244 1.5E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 346 430 1.5E-21 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 Gene3D G3DSA:3.20.20.70 92 454 8.9E-78 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 TIGRFAM TIGR03974 rSAM_six_Cys: SCIFF radical SAM maturase 4 449 4.3E-204 T 12-10-2018 IPR024025 SCIFF radical SAM maturase NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 Pfam PF13186 Iron-sulfur cluster-binding domain 346 407 1.1E-6 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 101 112 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_3173 2c3b2ea871dac2d2b5721b631d48316d 455 Pfam PF13353 4Fe-4S single cluster domain 101 220 2.7E-14 T 12-10-2018 NPD12_3748 ee3e329cc6b97a17a8788ef06ec9f216 437 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 41 384 5.4E-33 T 12-10-2018 IPR006427 Phage portal protein, HK97 NPD12_3748 ee3e329cc6b97a17a8788ef06ec9f216 437 Pfam PF04860 Phage portal protein 51 377 6.5E-48 T 12-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 Gene3D G3DSA:2.40.110.10 120 232 6.9E-40 T 12-10-2018 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 2.8E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 1.2E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 Gene3D G3DSA:1.10.540.10 1 117 3.2E-39 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 Gene3D G3DSA:1.20.140.10 233 377 6.0E-59 T 12-10-2018 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 PIRSF PIRSF016578 4 92 6.9E-8 T 12-10-2018 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 PIRSF PIRSF016578 127 377 6.1E-21 T 12-10-2018 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 SUPERFAMILY SSF56645 2 238 6.28E-80 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 SUPERFAMILY SSF47203 225 377 9.18E-61 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 NPD12_3416 8b97a3b01e73ba81f64807c55e5442ee 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 9.1E-55 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 5.8E-11 T 12-10-2018 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 341 361 5.8E-11 T 12-10-2018 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 5.8E-11 T 12-10-2018 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 5.8E-11 T 12-10-2018 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 Gene3D G3DSA:1.20.1250.20 263 474 3.2E-30 T 12-10-2018 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 Gene3D G3DSA:1.20.1720.10 18 254 1.4E-46 T 12-10-2018 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 Pfam PF07690 Major Facilitator Superfamily 25 413 1.3E-58 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 428 1.0E-88 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 NPD12_819 19ce8a00d37f88bbe0312e4c6d063f1a 477 SUPERFAMILY SSF103473 7 470 7.85E-74 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 155 712 2.2E-145 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 SMART SM01008 19 123 2.4E-45 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 SUPERFAMILY SSF56003 115 770 1.19E-163 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 Gene3D G3DSA:3.30.365.10 455 627 6.1E-104 T 12-10-2018 NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 SUPERFAMILY SSF54665 4 144 1.83E-41 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 Gene3D G3DSA:3.30.365.10 375 766 6.1E-104 T 12-10-2018 NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 Gene3D G3DSA:3.30.365.10 124 364 1.8E-101 T 12-10-2018 NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 19 123 2.9E-26 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 Gene3D G3DSA:3.30.365.10 17 288 1.8E-101 T 12-10-2018 NPD12_2887 c97b766b0482c0c0076cfccf7f74fdee 776 Gene3D G3DSA:3.90.1170.50 34 123 1.8E-101 T 12-10-2018 NPD12_1376 81bfa416d9bc694e09998ad0441d2a20 307 SMART SM00382 31 211 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1376 81bfa416d9bc694e09998ad0441d2a20 307 Gene3D G3DSA:3.40.50.300 1 240 1.3E-60 T 12-10-2018 NPD12_1376 81bfa416d9bc694e09998ad0441d2a20 307 SUPERFAMILY SSF52540 5 227 1.09E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1376 81bfa416d9bc694e09998ad0441d2a20 307 Pfam PF00005 ABC transporter 23 162 3.6E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1376 81bfa416d9bc694e09998ad0441d2a20 307 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 12-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 Gene3D G3DSA:2.40.50.970 1 73 2.9E-21 T 12-10-2018 IPR037254 HupF/HypC superfamily NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 Pfam PF01455 HupF/HypC family 1 56 3.7E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 SUPERFAMILY SSF159127 1 69 1.57E-19 T 12-10-2018 IPR037254 HupF/HypC superfamily NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.6E-11 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 2.6E-11 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 2.6E-11 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC NPD12_1985 c5c3f4081bb71bd597a6e8f9eedcfa33 75 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 56 5.4E-19 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC NPD12_1099 9d05ebae9090bab27e2415e633fbc893 320 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 12 314 9.3E-73 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 NPD12_1099 9d05ebae9090bab27e2415e633fbc893 320 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 320 90.138 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 NPD12_1099 9d05ebae9090bab27e2415e633fbc893 320 Pfam PF03186 CobD/Cbib protein 12 302 3.7E-100 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 NPD12_2495 66a59418ccfea3018920df3175f7827e 75 Pfam PF13083 KH domain 2 74 6.7E-25 T 12-10-2018 NPD12_2495 66a59418ccfea3018920df3175f7827e 75 SUPERFAMILY SSF54814 6 61 3.2E-8 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 NPD12_2495 66a59418ccfea3018920df3175f7827e 75 Gene3D G3DSA:3.30.300.20 5 72 5.0E-5 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta NPD12_2495 66a59418ccfea3018920df3175f7827e 75 Hamap MF_00088 UPF0109 protein . 1 75 23.746 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 PRINTS PR00123 ATP synthase A subunit signature 207 222 1.2E-13 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 PRINTS PR00123 ATP synthase A subunit signature 139 154 1.2E-13 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 PRINTS PR00123 ATP synthase A subunit signature 80 96 1.2E-13 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 PRINTS PR00123 ATP synthase A subunit signature 155 177 1.2E-13 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 Pfam PF00119 ATP synthase A chain 24 219 5.2E-47 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 25 219 1.1E-30 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 226 12.275 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 SUPERFAMILY SSF81336 72 219 1.83E-28 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 Gene3D G3DSA:1.20.120.220 72 226 1.4E-30 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_305 44c1cb9c1479b501948d440d987c5634 226 ProSitePatterns PS00449 ATP synthase a subunit signature. 158 167 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_2616 27284d61b8177f248d478f30948050b2 416 SUPERFAMILY SSF52540 2 219 8.58E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2616 27284d61b8177f248d478f30948050b2 416 Gene3D G3DSA:1.10.3710.10 328 416 3.3E-19 T 12-10-2018 NPD12_2616 27284d61b8177f248d478f30948050b2 416 Pfam PF12002 MgsA AAA+ ATPase C terminal 249 413 5.7E-62 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal NPD12_2616 27284d61b8177f248d478f30948050b2 416 Gene3D G3DSA:3.40.50.300 1 151 1.9E-40 T 12-10-2018 NPD12_2616 27284d61b8177f248d478f30948050b2 416 SUPERFAMILY SSF48019 234 415 3.74E-66 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 NPD12_2616 27284d61b8177f248d478f30948050b2 416 SMART SM00382 37 152 7.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2616 27284d61b8177f248d478f30948050b2 416 Pfam PF16193 AAA C-terminal domain 174 248 8.0E-18 T 12-10-2018 IPR032423 AAA C-terminal domain NPD12_2616 27284d61b8177f248d478f30948050b2 416 Gene3D G3DSA:1.20.272.10 224 327 6.0E-38 T 12-10-2018 NPD12_2616 27284d61b8177f248d478f30948050b2 416 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 151 7.8E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_2084 596f01d9e1eddbe4a30963c6af0264c3 569 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 341 520 1.5E-29 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2084 596f01d9e1eddbe4a30963c6af0264c3 569 SMART SM00304 209 263 3.1E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2084 596f01d9e1eddbe4a30963c6af0264c3 569 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 180 4.0E-32 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain NPD12_2084 596f01d9e1eddbe4a30963c6af0264c3 569 Gene3D G3DSA:1.10.287.950 271 568 1.6E-54 T 12-10-2018 NPD12_2084 596f01d9e1eddbe4a30963c6af0264c3 569 SMART SM00283 285 568 9.3E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2084 596f01d9e1eddbe4a30963c6af0264c3 569 Gene3D G3DSA:1.20.1480.50 171 270 4.3E-8 T 12-10-2018 NPD12_2084 596f01d9e1eddbe4a30963c6af0264c3 569 SUPERFAMILY SSF58104 231 568 5.41E-58 T 12-10-2018 NPD12_3532 c4d83c21975d5f9cb9be9253800be955 294 SUPERFAMILY SSF52540 1 152 4.92E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3532 c4d83c21975d5f9cb9be9253800be955 294 PIRSF PIRSF005052 1 288 1.2E-110 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 NPD12_3532 c4d83c21975d5f9cb9be9253800be955 294 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 285 41.898 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 NPD12_3532 c4d83c21975d5f9cb9be9253800be955 294 Pfam PF03668 P-loop ATPase protein family 1 284 6.9E-104 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 NPD12_3532 c4d83c21975d5f9cb9be9253800be955 294 Gene3D G3DSA:3.40.50.300 37 163 6.5E-9 T 12-10-2018 NPD12_975 65cddddb653c5430b7e5c5261ce7f71d 334 SUPERFAMILY SSF81345 6 331 2.75E-82 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_975 65cddddb653c5430b7e5c5261ce7f71d 334 Pfam PF01032 FecCD transport family 21 331 4.1E-93 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_975 65cddddb653c5430b7e5c5261ce7f71d 334 Gene3D G3DSA:1.10.3470.10 7 334 4.8E-92 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_2615 71f74f775b63a9ee0ac24456fbbbdbf3 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 1.5E-41 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_2615 71f74f775b63a9ee0ac24456fbbbdbf3 148 Gene3D G3DSA:1.10.10.10 1 143 3.8E-53 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2615 71f74f775b63a9ee0ac24456fbbbdbf3 148 Pfam PF02082 Transcriptional regulator 1 82 5.0E-29 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_2615 71f74f775b63a9ee0ac24456fbbbdbf3 148 SUPERFAMILY SSF46785 2 135 3.68E-36 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1070 aa62fb3145c57f4ca8943f933d8cc4d7 410 Gene3D G3DSA:3.75.10.10 1 410 1.8E-88 T 12-10-2018 NPD12_1070 aa62fb3145c57f4ca8943f933d8cc4d7 410 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 7 407 7.3E-65 T 12-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 NPD12_1070 aa62fb3145c57f4ca8943f933d8cc4d7 410 SUPERFAMILY SSF55909 4 407 7.85E-73 T 12-10-2018 NPD12_1634 9b01c2492f6594bb3154e8ceb49d84ef 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 246 7.7E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1634 9b01c2492f6594bb3154e8ceb49d84ef 253 SUPERFAMILY SSF161098 60 246 3.4E-22 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1634 9b01c2492f6594bb3154e8ceb49d84ef 253 Gene3D G3DSA:1.10.3720.10 54 250 4.6E-20 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_178 3a35209ff834fc6ab78396c87bf520b0 369 Gene3D G3DSA:1.20.1250.20 179 366 7.2E-32 T 12-10-2018 NPD12_178 3a35209ff834fc6ab78396c87bf520b0 369 Pfam PF07690 Major Facilitator Superfamily 10 305 3.1E-27 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_178 3a35209ff834fc6ab78396c87bf520b0 369 Gene3D G3DSA:1.20.1250.20 1 178 2.7E-25 T 12-10-2018 NPD12_178 3a35209ff834fc6ab78396c87bf520b0 369 SUPERFAMILY SSF103473 6 367 7.98E-46 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_3585 584f7dc4e36c38932fc0e8e8e74a490b 303 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 5 298 7.4E-146 T 12-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 NPD12_3585 584f7dc4e36c38932fc0e8e8e74a490b 303 PIRSF PIRSF000428 1 302 4.5E-98 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_3585 584f7dc4e36c38932fc0e8e8e74a490b 303 SUPERFAMILY SSF53659 4 298 2.54E-68 T 12-10-2018 NPD12_3585 584f7dc4e36c38932fc0e8e8e74a490b 303 Gene3D G3DSA:3.40.718.10 2 300 5.5E-109 T 12-10-2018 NPD12_3585 584f7dc4e36c38932fc0e8e8e74a490b 303 Pfam PF01515 Phosphate acetyl/butaryl transferase 76 295 6.6E-66 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 Pfam PF00072 Response regulator receiver domain 4 113 4.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 Gene3D G3DSA:1.10.10.10 138 237 5.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 SUPERFAMILY SSF46894 133 235 1.47E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 SMART SM00862 157 235 4.6E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 Gene3D G3DSA:3.40.50.2300 1 122 2.0E-34 T 12-10-2018 NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 SMART SM00448 2 112 5.4E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 234 7.3E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_971 0c4ad126405df459dc04c598f3ec3c4c 237 SUPERFAMILY SSF52172 3 126 5.98E-38 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_3480 9f84608548e646fd0ddfd6a19b60901f 392 SUPERFAMILY SSF161111 25 225 7.06E-52 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily NPD12_3480 9f84608548e646fd0ddfd6a19b60901f 392 Pfam PF16916 Dimerisation domain of Zinc Transporter 229 304 1.9E-12 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain NPD12_3480 9f84608548e646fd0ddfd6a19b60901f 392 Gene3D G3DSA:1.20.1510.10 29 224 4.9E-56 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily NPD12_3480 9f84608548e646fd0ddfd6a19b60901f 392 Gene3D G3DSA:3.30.70.1350 226 307 7.5E-17 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 NPD12_3480 9f84608548e646fd0ddfd6a19b60901f 392 Pfam PF01545 Cation efflux family 32 224 1.3E-45 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 NPD12_3480 9f84608548e646fd0ddfd6a19b60901f 392 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 32 294 4.8E-59 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 NPD12_3480 9f84608548e646fd0ddfd6a19b60901f 392 SUPERFAMILY SSF160240 227 306 1.57E-17 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 NPD12_1230 c4d2a9944fe72f34ad3288ca8f168307 419 Gene3D G3DSA:1.10.630.10 3 419 3.0E-159 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 NPD12_1230 c4d2a9944fe72f34ad3288ca8f168307 419 SUPERFAMILY SSF48264 13 417 5.89E-66 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 NPD12_1230 c4d2a9944fe72f34ad3288ca8f168307 419 Pfam PF00067 Cytochrome P450 277 396 3.2E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 NPD12_1230 c4d2a9944fe72f34ad3288ca8f168307 419 PRINTS PR00463 E-class P450 group I signature 365 388 6.0E-8 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 NPD12_1230 c4d2a9944fe72f34ad3288ca8f168307 419 PRINTS PR00463 E-class P450 group I signature 319 343 6.0E-8 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 NPD12_1230 c4d2a9944fe72f34ad3288ca8f168307 419 PRINTS PR00463 E-class P450 group I signature 253 279 6.0E-8 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 SUPERFAMILY SSF52540 3 271 3.64E-127 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 Gene3D G3DSA:3.40.50.300 1 286 1.0E-137 T 12-10-2018 NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 Hamap MF_01227 CTP synthase [pyrG]. 3 533 53.155 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 528 2.2E-263 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 Pfam PF00117 Glutamine amidotransferase class-I 303 528 4.4E-63 T 12-10-2018 IPR017926 Glutamine amidotransferase NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 Gene3D G3DSA:3.40.50.880 287 533 2.6E-108 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 Pfam PF06418 CTP synthase N-terminus 4 268 1.5E-132 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 NPD12_286 37f7329a7b0437e7b80996eacfc00b4d 533 SUPERFAMILY SSF52317 291 531 2.57E-87 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1595 4021d9698d458d1c1c086509c89c8281 223 SMART SM00448 1 112 1.7E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1595 4021d9698d458d1c1c086509c89c8281 223 SUPERFAMILY SSF52172 1 168 8.11E-37 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1595 4021d9698d458d1c1c086509c89c8281 223 SMART SM00862 145 220 1.1E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1595 4021d9698d458d1c1c086509c89c8281 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 8.2E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1595 4021d9698d458d1c1c086509c89c8281 223 Gene3D G3DSA:1.10.10.10 123 223 2.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1595 4021d9698d458d1c1c086509c89c8281 223 Gene3D G3DSA:3.40.50.2300 1 121 6.3E-36 T 12-10-2018 NPD12_1595 4021d9698d458d1c1c086509c89c8281 223 Pfam PF00072 Response regulator receiver domain 4 112 2.7E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1562 f43715be096e228df56d31b14e459675 297 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 6 285 1.0E-94 T 12-10-2018 IPR003797 DegV NPD12_1562 f43715be096e228df56d31b14e459675 297 Gene3D G3DSA:3.40.50.10440 6 148 1.4E-51 T 12-10-2018 NPD12_1562 f43715be096e228df56d31b14e459675 297 Gene3D G3DSA:3.30.1180.10 159 290 5.8E-37 T 12-10-2018 NPD12_1562 f43715be096e228df56d31b14e459675 297 Pfam PF02645 Uncharacterised protein, DegV family COG1307 6 285 4.7E-80 T 12-10-2018 IPR003797 DegV NPD12_1562 f43715be096e228df56d31b14e459675 297 SUPERFAMILY SSF82549 4 287 5.75E-84 T 12-10-2018 NPD12_1562 f43715be096e228df56d31b14e459675 297 Gene3D G3DSA:2.20.28.50 29 65 1.4E-51 T 12-10-2018 NPD12_425 296033cf849f04458f42a47ec74559f2 159 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 14 153 4.1E-56 T 12-10-2018 IPR014203 Sporulation stage V, protein AC NPD12_425 296033cf849f04458f42a47ec74559f2 159 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 32 149 5.9E-37 T 12-10-2018 IPR005562 SpoVA NPD12_206 d40c3aa13e6ef55e82bf731394306dda 302 PIRSF PIRSF028757 1 302 6.0E-95 T 12-10-2018 IPR003507 Peptidase family S66 NPD12_206 d40c3aa13e6ef55e82bf731394306dda 302 SUPERFAMILY SSF141986 137 296 7.59E-44 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily NPD12_206 d40c3aa13e6ef55e82bf731394306dda 302 Gene3D G3DSA:3.50.30.60 163 298 7.5E-44 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily NPD12_206 d40c3aa13e6ef55e82bf731394306dda 302 SUPERFAMILY SSF52317 2 160 2.11E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_206 d40c3aa13e6ef55e82bf731394306dda 302 Gene3D G3DSA:3.40.50.10740 1 154 1.3E-54 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal NPD12_206 d40c3aa13e6ef55e82bf731394306dda 302 Pfam PF02016 LD-carboxypeptidase 12 290 9.0E-84 T 12-10-2018 IPR003507 Peptidase family S66 NPD12_3572 34b37007a15bc3b808eea034587e4ab9 121 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 9 116 5.0E-29 T 12-10-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 NPD12_3572 34b37007a15bc3b808eea034587e4ab9 121 Gene3D G3DSA:2.40.33.40 1 120 9.0E-35 T 12-10-2018 IPR036665 Phosphotransferase system, glucitol/sorbitol-specific IIA component superfamily GO:0005737|GO:0008982|GO:0009401 NPD12_3572 34b37007a15bc3b808eea034587e4ab9 121 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 4 116 2.1E-42 T 12-10-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 NPD12_3572 34b37007a15bc3b808eea034587e4ab9 121 SUPERFAMILY SSF141530 3 118 1.7E-39 T 12-10-2018 IPR036665 Phosphotransferase system, glucitol/sorbitol-specific IIA component superfamily GO:0005737|GO:0008982|GO:0009401 NPD12_1356 3adb59b1fc87de87c9a6acddbb44a3f5 307 Pfam PF04227 Indigoidine synthase A like protein 11 301 4.5E-139 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 NPD12_1356 3adb59b1fc87de87c9a6acddbb44a3f5 307 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 10 304 44.655 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 NPD12_1356 3adb59b1fc87de87c9a6acddbb44a3f5 307 SUPERFAMILY SSF110581 4 303 9.15E-119 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 NPD12_1356 3adb59b1fc87de87c9a6acddbb44a3f5 307 Gene3D G3DSA:3.40.1790.10 2 307 1.4E-143 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 Gene3D G3DSA:1.20.1480.50 173 271 2.8E-12 T 12-10-2018 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 Gene3D G3DSA:1.10.287.950 272 571 7.3E-53 T 12-10-2018 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 356 523 2.3E-28 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 SUPERFAMILY SSF58104 241 571 2.79E-54 T 12-10-2018 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 SMART SM00283 281 571 1.0E-32 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 181 5.1E-31 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 SMART SM00304 211 266 0.0016 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 420 3.1E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 422 451 3.1E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 3.1E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_1620 525fd04ac18468cdfa0c38eb96449316 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 316 345 3.1E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_2349 7ab9a742c4fe0a3885b425b1b7530ffa 254 Gene3D G3DSA:3.30.1330.60 83 243 2.3E-45 T 12-10-2018 IPR036737 OmpA-like domain superfamily NPD12_2349 7ab9a742c4fe0a3885b425b1b7530ffa 254 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 53 2.4E-19 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain NPD12_2349 7ab9a742c4fe0a3885b425b1b7530ffa 254 SUPERFAMILY SSF103088 117 234 6.67E-30 T 12-10-2018 IPR036737 OmpA-like domain superfamily NPD12_2349 7ab9a742c4fe0a3885b425b1b7530ffa 254 Pfam PF00691 OmpA family 129 228 9.4E-19 T 12-10-2018 IPR006665 OmpA-like domain NPD12_2349 7ab9a742c4fe0a3885b425b1b7530ffa 254 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 217 237 4.7E-7 T 12-10-2018 NPD12_2349 7ab9a742c4fe0a3885b425b1b7530ffa 254 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 197 216 4.7E-7 T 12-10-2018 NPD12_2349 7ab9a742c4fe0a3885b425b1b7530ffa 254 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 90 109 4.7E-7 T 12-10-2018 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 SUPERFAMILY SSF50494 95 305 7.09E-59 T 12-10-2018 IPR009003 Peptidase S1, PA clan NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 SUPERFAMILY SSF50156 278 382 1.13E-22 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 Pfam PF13180 PDZ domain 297 382 4.8E-17 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 SMART SM00228 297 373 8.0E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 PRINTS PR00834 HtrA/DegQ protease family signature 135 147 7.0E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 PRINTS PR00834 HtrA/DegQ protease family signature 156 176 7.0E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 PRINTS PR00834 HtrA/DegQ protease family signature 233 250 7.0E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 PRINTS PR00834 HtrA/DegQ protease family signature 331 343 7.0E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 PRINTS PR00834 HtrA/DegQ protease family signature 255 272 7.0E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 PRINTS PR00834 HtrA/DegQ protease family signature 196 220 7.0E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 Pfam PF13365 Trypsin-like peptidase domain 126 262 3.0E-33 T 12-10-2018 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 Gene3D G3DSA:2.40.10.10 187 297 1.4E-37 T 12-10-2018 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 Gene3D G3DSA:2.40.10.10 76 186 2.5E-30 T 12-10-2018 NPD12_11 6107d9db65530a2ceb7e7e290d7381dd 390 Gene3D G3DSA:2.30.42.10 298 390 1.7E-25 T 12-10-2018 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 Gene3D G3DSA:3.40.47.10 126 389 9.0E-167 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 Pfam PF00108 Thiolase, N-terminal domain 4 262 1.0E-109 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 SUPERFAMILY SSF53901 270 391 1.13E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 2.4E-156 T 12-10-2018 IPR002155 Thiolase GO:0016747 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 Pfam PF02803 Thiolase, C-terminal domain 270 391 3.5E-53 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 PIRSF PIRSF000429 1 392 1.0E-141 T 12-10-2018 IPR002155 Thiolase GO:0016747 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 SUPERFAMILY SSF53901 3 269 1.48E-94 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_3311 4c142533b8a3ad30b2fa0f1e9f905f54 392 Gene3D G3DSA:3.40.47.10 6 275 9.0E-167 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 NPD12_1744 e9ee9307cfc72273d20c81bb9d9a3746 340 Gene3D G3DSA:3.20.20.210 1 336 1.6E-75 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_1744 e9ee9307cfc72273d20c81bb9d9a3746 340 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 336 6.1E-79 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 NPD12_1744 e9ee9307cfc72273d20c81bb9d9a3746 340 TIGRFAM TIGR01463 mtaA_cmuA: methyltransferase, MtaA/CmuA family 2 336 5.5E-75 T 12-10-2018 IPR006360 Methyltransferase MtaA/CmuA GO:0006730|GO:0008168 NPD12_1744 e9ee9307cfc72273d20c81bb9d9a3746 340 SUPERFAMILY SSF51726 1 338 8.5E-65 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_316 841ecea1e1d7a29feb1890b12643504f 248 Pfam PF01551 Peptidase family M23 143 242 1.1E-21 T 12-10-2018 IPR016047 Peptidase M23 NPD12_316 841ecea1e1d7a29feb1890b12643504f 248 Gene3D G3DSA:2.70.70.10 80 248 1.4E-28 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_316 841ecea1e1d7a29feb1890b12643504f 248 SUPERFAMILY SSF51261 61 246 2.25E-27 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_1518 facb6717b9a113c19a0e2140e54ed692 173 SUPERFAMILY SSF56112 1 168 5.1E-33 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_1518 facb6717b9a113c19a0e2140e54ed692 173 Gene3D G3DSA:3.90.1200.10 1 173 4.0E-57 T 12-10-2018 NPD12_1310 961f3e73517dc5eb690949f325147640 327 Gene3D G3DSA:3.30.930.10 65 266 3.4E-60 T 12-10-2018 NPD12_1310 961f3e73517dc5eb690949f325147640 327 Gene3D G3DSA:2.30.30.100 275 323 5.1E-13 T 12-10-2018 NPD12_1310 961f3e73517dc5eb690949f325147640 327 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 320 4.1E-56 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_1310 961f3e73517dc5eb690949f325147640 327 Pfam PF03099 Biotin/lipoate A/B protein ligase family 87 208 7.8E-15 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 NPD12_1310 961f3e73517dc5eb690949f325147640 327 SUPERFAMILY SSF46785 4 57 3.26E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1310 961f3e73517dc5eb690949f325147640 327 SUPERFAMILY SSF55681 68 257 4.81E-54 T 12-10-2018 NPD12_1310 961f3e73517dc5eb690949f325147640 327 SUPERFAMILY SSF50037 276 322 9.61E-8 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal NPD12_1310 961f3e73517dc5eb690949f325147640 327 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 4 321 35.892 T 12-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 NPD12_1310 961f3e73517dc5eb690949f325147640 327 Pfam PF08279 HTH domain 3 56 1.2E-15 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_1310 961f3e73517dc5eb690949f325147640 327 Gene3D G3DSA:1.10.10.10 1 61 6.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1310 961f3e73517dc5eb690949f325147640 327 Pfam PF02237 Biotin protein ligase C terminal domain 275 321 5.4E-10 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 NPD12_2595 8fe89a6903822a33849aecfa7e492181 66 Gene3D G3DSA:3.40.630.30 3 66 2.1E-9 T 12-10-2018 NPD12_2163 a7321907ff2cdcea9d0e5b305e095eb7 92 Pfam PF03477 ATP cone domain 1 90 2.4E-10 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 SUPERFAMILY SSF52540 225 407 1.77E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 Gene3D G3DSA:3.40.50.300 240 426 8.7E-64 T 12-10-2018 NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 3 187 2.3E-39 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 Pfam PF04851 Type III restriction enzyme, res subunit 239 403 7.7E-35 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 Gene3D G3DSA:3.90.1570.50 3 232 3.6E-81 T 12-10-2018 NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 660 913 9.5E-55 T 12-10-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 SUPERFAMILY SSF52540 260 627 6.04E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 SMART SM00487 237 429 5.5E-15 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 Gene3D G3DSA:3.40.50.300 427 663 2.4E-81 T 12-10-2018 NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 Gene3D G3DSA:3.90.640.50 29 101 3.6E-81 T 12-10-2018 NPD12_2225 ceafeb666f61685f3a5bff8663277523 916 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 7 652 6.5E-144 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 NPD12_3654 ab3c1111477793c4ca002fc2433e5430 49 Pfam PF00471 Ribosomal protein L33 3 49 1.8E-23 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3654 ab3c1111477793c4ca002fc2433e5430 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 1.8E-21 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3654 ab3c1111477793c4ca002fc2433e5430 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3654 ab3c1111477793c4ca002fc2433e5430 49 Gene3D G3DSA:2.20.28.120 1 49 6.4E-25 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3654 ab3c1111477793c4ca002fc2433e5430 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.67 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3654 ab3c1111477793c4ca002fc2433e5430 49 SUPERFAMILY SSF57829 1 49 3.66E-20 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 2.1E-30 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 PIRSF PIRSF006092 1 160 1.8E-51 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 SUPERFAMILY SSF46557 5 80 3.4E-27 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 158 1.2E-25 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 2.2E-57 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 32.288 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 Gene3D G3DSA:1.10.287.180 4 78 5.0E-30 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 SUPERFAMILY SSF54534 84 157 5.23E-22 T 12-10-2018 NPD12_3693 45d1c5b2646b99e9a877e880df6097e9 160 Gene3D G3DSA:3.10.50.30 80 160 5.5E-26 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 Pfam PF00842 Alanine racemase, C-terminal domain 246 373 1.7E-48 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 Hamap MF_01201 Alanine racemase. 5 374 35.236 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 262 277 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 279 294 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 300 317 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 66 84 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 205 232 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 162 173 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 127 139 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 356 369 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 PRINTS PR00992 Alanine racemase signature 30 46 3.3E-63 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 Pfam PF01168 Alanine racemase, N-terminal domain 12 232 6.7E-63 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 TIGRFAM TIGR00492 alr: alanine racemase 6 373 9.3E-124 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 SUPERFAMILY SSF50621 239 381 3.35E-54 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 SUPERFAMILY SSF51419 12 247 6.87E-65 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 SMART SM01005 246 374 2.6E-73 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 Gene3D G3DSA:3.20.20.10 14 228 3.1E-136 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 Gene3D G3DSA:2.40.37.10 9 373 3.1E-136 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 NPD12_3553 613897fadb6e301b62382f9c980cdb8a 386 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 35 45 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_2842 b16f8813f86e0d935c66c202625c0498 266 Pfam PF05857 TraX protein 7 260 2.3E-39 T 12-10-2018 IPR008875 TraX NPD12_570 108407aa14adf7127080494998457808 417 SUPERFAMILY SSF47413 5 63 6.57E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_570 108407aa14adf7127080494998457808 417 Gene3D G3DSA:1.10.260.40 4 65 4.7E-13 T 12-10-2018 NPD12_570 108407aa14adf7127080494998457808 417 SMART SM00530 9 63 3.4E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_570 108407aa14adf7127080494998457808 417 SMART SM00028 265 298 35.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 SMART SM00028 344 377 250.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 SMART SM00028 148 181 120.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 SMART SM00028 384 417 0.018 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 SMART SM00028 188 221 300.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 SUPERFAMILY SSF48452 143 298 5.24E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 Gene3D G3DSA:1.25.40.10 316 417 1.4E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 SUPERFAMILY SSF48452 259 416 3.48E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_570 108407aa14adf7127080494998457808 417 Pfam PF12844 Helix-turn-helix domain 7 68 4.3E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 SUPERFAMILY SSF53383 4 378 3.99E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 PIRSF PIRSF005572 2 384 1.9E-133 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 56.491 T 12-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 Gene3D G3DSA:3.40.640.10 16 257 1.0E-157 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 5 386 5.5E-189 T 12-10-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 Pfam PF00266 Aminotransferase class-V 5 369 4.0E-85 T 12-10-2018 IPR000192 Aminotransferase class V domain NPD12_2614 54004bcd45357eb2fb6adb3878410b76 397 Gene3D G3DSA:3.90.1150.10 5 376 1.0E-157 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_3611 930462988ff043124525fbefbbc5226f 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 5.0E-74 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 NPD12_3611 930462988ff043124525fbefbbc5226f 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3611 930462988ff043124525fbefbbc5226f 206 Pfam PF01479 S4 domain 98 145 1.9E-21 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3611 930462988ff043124525fbefbbc5226f 206 SMART SM01390 3 97 2.2E-56 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 NPD12_3611 930462988ff043124525fbefbbc5226f 206 SMART SM00363 98 160 2.2E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3611 930462988ff043124525fbefbbc5226f 206 Gene3D G3DSA:1.10.1050.10 6 206 2.0E-86 T 12-10-2018 NPD12_3611 930462988ff043124525fbefbbc5226f 206 SUPERFAMILY SSF55174 3 206 4.32E-72 T 12-10-2018 NPD12_3611 930462988ff043124525fbefbbc5226f 206 Gene3D G3DSA:3.10.290.10 97 191 2.0E-86 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_3611 930462988ff043124525fbefbbc5226f 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.3 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 NPD12_3611 930462988ff043124525fbefbbc5226f 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 2.2E-34 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 NPD12_1087 ae08dd72d74e74467fb866225627ab10 223 Gene3D G3DSA:3.40.50.12740 2 140 8.8E-41 T 12-10-2018 NPD12_1087 ae08dd72d74e74467fb866225627ab10 223 SMART SM00862 146 220 9.9E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1087 ae08dd72d74e74467fb866225627ab10 223 SUPERFAMILY SSF52172 1 179 2.7E-42 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1087 ae08dd72d74e74467fb866225627ab10 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 2.5E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1087 ae08dd72d74e74467fb866225627ab10 223 SMART SM00448 2 113 2.8E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1087 ae08dd72d74e74467fb866225627ab10 223 Pfam PF00072 Response regulator receiver domain 4 113 1.6E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1087 ae08dd72d74e74467fb866225627ab10 223 Gene3D G3DSA:1.10.10.10 141 223 1.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2760 273e69679a78b7a1e7f6b165689f62d4 384 Gene3D G3DSA:3.40.50.2000 4 368 5.0E-85 T 12-10-2018 NPD12_2760 273e69679a78b7a1e7f6b165689f62d4 384 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 370 5.6E-84 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 NPD12_2760 273e69679a78b7a1e7f6b165689f62d4 384 SUPERFAMILY SSF53756 1 378 1.57E-86 T 12-10-2018 NPD12_2760 273e69679a78b7a1e7f6b165689f62d4 384 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 3 369 4.5E-137 T 12-10-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 NPD12_2760 273e69679a78b7a1e7f6b165689f62d4 384 Gene3D G3DSA:3.40.50.2000 190 356 5.0E-85 T 12-10-2018 NPD12_1284 3019c92a93af4aa5e5993b83b16397e8 216 SUPERFAMILY SSF53098 30 212 5.4E-7 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_1284 3019c92a93af4aa5e5993b83b16397e8 216 Pfam PF13482 RNase_H superfamily 32 212 2.2E-43 T 12-10-2018 IPR038720 YprB, ribonuclease H-like domain NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 SMART SM00450 58 179 8.8E-19 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 SMART SM00450 201 320 4.1E-21 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 Pfam PF00581 Rhodanese-like domain 61 175 1.4E-20 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 Pfam PF00581 Rhodanese-like domain 205 316 2.8E-17 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 ProSitePatterns PS00380 Rhodanese signature 1. 83 94 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 Gene3D G3DSA:3.40.250.10 198 324 2.2E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 SUPERFAMILY SSF52821 198 323 5.11E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 Gene3D G3DSA:3.40.250.10 41 197 4.2E-37 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_2662 1a8fb39dd1078b4afcb3709ccdfe395b 324 SUPERFAMILY SSF52821 52 194 1.23E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_2371 4ba0f0911915328a4a444bedf9a06dbd 180 SUPERFAMILY SSF52949 8 175 1.85E-66 T 12-10-2018 NPD12_2371 4ba0f0911915328a4a444bedf9a06dbd 180 Gene3D G3DSA:3.40.220.10 3 179 1.7E-72 T 12-10-2018 NPD12_2371 4ba0f0911915328a4a444bedf9a06dbd 180 Pfam PF01661 Macro domain 25 141 4.8E-45 T 12-10-2018 IPR002589 Macro domain NPD12_2371 4ba0f0911915328a4a444bedf9a06dbd 180 SMART SM00506 8 141 9.7E-51 T 12-10-2018 IPR002589 Macro domain NPD12_179 ca697ca3725092f9ab983858916e981b 314 Pfam PF13302 Acetyltransferase (GNAT) domain 148 286 2.2E-20 T 12-10-2018 IPR000182 GNAT domain NPD12_179 ca697ca3725092f9ab983858916e981b 314 SUPERFAMILY SSF55729 139 310 1.39E-41 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_179 ca697ca3725092f9ab983858916e981b 314 Gene3D G3DSA:3.40.630.30 1 131 4.5E-25 T 12-10-2018 NPD12_179 ca697ca3725092f9ab983858916e981b 314 Gene3D G3DSA:3.40.630.30 135 313 2.5E-41 T 12-10-2018 NPD12_2728 ee2c6937bf342c3851bfbef210b23725 355 SMART SM00858 298 355 5.9E-9 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 NPD12_2728 ee2c6937bf342c3851bfbef210b23725 355 Gene3D G3DSA:3.90.1210.10 287 355 8.3E-24 T 12-10-2018 NPD12_2728 ee2c6937bf342c3851bfbef210b23725 355 Pfam PF03102 NeuB family 42 281 1.3E-79 T 12-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 NPD12_2728 ee2c6937bf342c3851bfbef210b23725 355 SUPERFAMILY SSF51569 8 308 6.96E-78 T 12-10-2018 NPD12_2728 ee2c6937bf342c3851bfbef210b23725 355 SUPERFAMILY SSF51269 292 355 1.03E-18 T 12-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 NPD12_2728 ee2c6937bf342c3851bfbef210b23725 355 Gene3D G3DSA:3.20.20.70 5 281 1.7E-84 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2728 ee2c6937bf342c3851bfbef210b23725 355 Pfam PF08666 SAF domain 299 353 8.3E-11 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 NPD12_857 28ba2e2737b6d717a01e188c1e230d46 377 SUPERFAMILY SSF116734 173 375 6.54E-38 T 12-10-2018 NPD12_857 28ba2e2737b6d717a01e188c1e230d46 377 Gene3D G3DSA:3.90.220.20 191 328 9.8E-35 T 12-10-2018 NPD12_857 28ba2e2737b6d717a01e188c1e230d46 377 Pfam PF01420 Type I restriction modification DNA specificity domain 192 358 3.7E-13 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 NPD12_857 28ba2e2737b6d717a01e188c1e230d46 377 Pfam PF01420 Type I restriction modification DNA specificity domain 2 163 4.0E-16 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 NPD12_857 28ba2e2737b6d717a01e188c1e230d46 377 Gene3D G3DSA:3.90.220.20 2 179 3.5E-27 T 12-10-2018 NPD12_857 28ba2e2737b6d717a01e188c1e230d46 377 Gene3D G3DSA:1.10.287.1120 329 374 9.8E-35 T 12-10-2018 NPD12_857 28ba2e2737b6d717a01e188c1e230d46 377 SUPERFAMILY SSF116734 2 181 1.05E-31 T 12-10-2018 NPD12_125 9e84b06cc2db8a6a2bcc51e5594e5e67 69 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 69 3.0E-19 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor NPD12_125 9e84b06cc2db8a6a2bcc51e5594e5e67 69 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.398 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor NPD12_125 9e84b06cc2db8a6a2bcc51e5594e5e67 69 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 68 3.3E-30 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor NPD12_125 9e84b06cc2db8a6a2bcc51e5594e5e67 69 Pfam PF01809 Haemolytic domain 2 68 1.3E-31 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor NPD12_125 9e84b06cc2db8a6a2bcc51e5594e5e67 69 SMART SM01234 1 68 1.8E-43 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor NPD12_1506 9889a02809d9dc6b6403d80cabfac5fc 364 Pfam PF04865 Baseplate J-like protein 63 320 9.0E-55 T 12-10-2018 IPR006949 Baseplate protein J-like NPD12_2090 db8907bd892d6a597e1158d5742a7d2b 250 SMART SM00448 117 227 5.7E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2090 db8907bd892d6a597e1158d5742a7d2b 250 SUPERFAMILY SSF52172 5 106 7.68E-14 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2090 db8907bd892d6a597e1158d5742a7d2b 250 SUPERFAMILY SSF52172 110 250 3.42E-20 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2090 db8907bd892d6a597e1158d5742a7d2b 250 Gene3D G3DSA:3.40.50.2300 1 118 7.6E-15 T 12-10-2018 NPD12_2090 db8907bd892d6a597e1158d5742a7d2b 250 Pfam PF00072 Response regulator receiver domain 4 101 7.8E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2090 db8907bd892d6a597e1158d5742a7d2b 250 Pfam PF00072 Response regulator receiver domain 119 227 2.3E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2090 db8907bd892d6a597e1158d5742a7d2b 250 Gene3D G3DSA:3.40.50.2300 119 233 3.3E-19 T 12-10-2018 NPD12_1327 c43d42bfe111b1e8909c7987e7acf057 103 Pfam PF00581 Rhodanese-like domain 7 97 5.4E-18 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1327 c43d42bfe111b1e8909c7987e7acf057 103 Gene3D G3DSA:3.40.250.10 2 102 8.2E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1327 c43d42bfe111b1e8909c7987e7acf057 103 SMART SM00450 7 103 1.6E-17 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1327 c43d42bfe111b1e8909c7987e7acf057 103 SUPERFAMILY SSF52821 3 97 3.4E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_2862 b117220c94c11ea6979033542d0feff3 380 Gene3D G3DSA:3.20.20.140 55 348 4.1E-137 T 12-10-2018 NPD12_2862 b117220c94c11ea6979033542d0feff3 380 PIRSF PIRSF038994 1 380 2.9E-131 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 NPD12_2862 b117220c94c11ea6979033542d0feff3 380 Gene3D G3DSA:2.30.40.10 9 376 4.1E-137 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2862 b117220c94c11ea6979033542d0feff3 380 Pfam PF01979 Amidohydrolase family 51 377 3.4E-31 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 NPD12_2862 b117220c94c11ea6979033542d0feff3 380 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 375 1.4E-114 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 NPD12_2862 b117220c94c11ea6979033542d0feff3 380 SUPERFAMILY SSF51338 2 379 3.05E-17 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2862 b117220c94c11ea6979033542d0feff3 380 SUPERFAMILY SSF51556 55 348 1.36E-93 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_3148 1feb3322825b8ea5b0b605b7628c1521 266 Gene3D G3DSA:3.40.50.300 59 243 2.9E-51 T 12-10-2018 NPD12_3148 1feb3322825b8ea5b0b605b7628c1521 266 SUPERFAMILY SSF52540 75 236 4.69E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3148 1feb3322825b8ea5b0b605b7628c1521 266 Pfam PF01695 IstB-like ATP binding protein 76 225 4.4E-14 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 NPD12_3148 1feb3322825b8ea5b0b605b7628c1521 266 SMART SM00382 111 237 1.9E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1771 1a3fcfe1b8d2f5f7d37fee6d5468b3f2 117 SUPERFAMILY SSF46785 12 111 3.15E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1771 1a3fcfe1b8d2f5f7d37fee6d5468b3f2 117 Gene3D G3DSA:1.10.10.10 4 116 3.1E-41 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1771 1a3fcfe1b8d2f5f7d37fee6d5468b3f2 117 Pfam PF01638 HxlR-like helix-turn-helix 25 113 5.8E-39 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 SUPERFAMILY SSF50447 175 260 3.93E-25 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 SUPERFAMILY SSF50465 266 364 1.15E-29 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 SUPERFAMILY SSF52540 3 169 6.12E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 SUPERFAMILY SSF46785 584 634 1.5E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 PRINTS PR00315 GTP-binding elongation factor signature 110 119 5.3E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 PRINTS PR00315 GTP-binding elongation factor signature 73 84 5.3E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 PRINTS PR00315 GTP-binding elongation factor signature 5 18 5.3E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 PRINTS PR00315 GTP-binding elongation factor signature 57 67 5.3E-7 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Pfam PF03144 Elongation factor Tu domain 2 194 260 1.7E-12 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Pfam PF09106 Elongation factor SelB, winged helix 451 505 1.7E-13 T 12-10-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 29 44 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Gene3D G3DSA:1.10.10.10 577 635 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 4 634 9.2E-118 T 12-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Gene3D G3DSA:1.10.10.2770 445 574 2.4E-29 T 12-10-2018 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Pfam PF00009 Elongation factor Tu GTP binding domain 3 168 9.6E-35 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 SUPERFAMILY SSF46785 515 573 6.26E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Gene3D G3DSA:2.40.30.10 176 264 7.8E-30 T 12-10-2018 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 164 4.1E-15 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Gene3D G3DSA:2.40.30.10 272 366 6.5E-6 T 12-10-2018 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 SUPERFAMILY SSF46785 440 512 2.99E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Pfam PF09107 Elongation factor SelB, winged helix 589 634 1.9E-20 T 12-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 NPD12_3080 f3e557bc0a5bf46b5abe91c80c184663 635 Gene3D G3DSA:3.40.50.300 2 170 1.7E-51 T 12-10-2018 NPD12_129 03d57016926c8b708cc589f002ee9302 367 SUPERFAMILY SSF55979 123 242 4.45E-27 T 12-10-2018 NPD12_129 03d57016926c8b708cc589f002ee9302 367 SUPERFAMILY SSF55979 1 117 3.34E-27 T 12-10-2018 NPD12_129 03d57016926c8b708cc589f002ee9302 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 243 363 1.1E-29 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 NPD12_129 03d57016926c8b708cc589f002ee9302 367 Gene3D G3DSA:3.10.150.10 1 240 7.5E-121 T 12-10-2018 NPD12_129 03d57016926c8b708cc589f002ee9302 367 Gene3D G3DSA:3.70.10.10 137 362 7.5E-121 T 12-10-2018 NPD12_129 03d57016926c8b708cc589f002ee9302 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 3.5E-30 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 NPD12_129 03d57016926c8b708cc589f002ee9302 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 239 6.8E-29 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 NPD12_129 03d57016926c8b708cc589f002ee9302 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 364 1.9E-95 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 NPD12_129 03d57016926c8b708cc589f002ee9302 367 PIRSF PIRSF000804 1 365 7.4E-114 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 NPD12_129 03d57016926c8b708cc589f002ee9302 367 SMART SM00480 17 360 7.0E-114 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 NPD12_129 03d57016926c8b708cc589f002ee9302 367 SUPERFAMILY SSF55979 244 364 2.51E-34 T 12-10-2018 NPD12_30 706944957b0e9263711b769371b85a47 220 Pfam PF01381 Helix-turn-helix 8 60 1.3E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_30 706944957b0e9263711b769371b85a47 220 SUPERFAMILY SSF51306 120 213 1.38E-10 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily NPD12_30 706944957b0e9263711b769371b85a47 220 SMART SM00530 7 62 1.5E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_30 706944957b0e9263711b769371b85a47 220 SUPERFAMILY SSF47413 4 62 2.68E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_30 706944957b0e9263711b769371b85a47 220 Gene3D G3DSA:1.10.260.40 1 77 3.8E-15 T 12-10-2018 NPD12_697 98033b903fd2a68efa761019c80198f0 221 SMART SM00382 32 218 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_697 98033b903fd2a68efa761019c80198f0 221 Pfam PF00005 ABC transporter 23 169 3.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_697 98033b903fd2a68efa761019c80198f0 221 Gene3D G3DSA:3.40.50.300 1 221 1.1E-65 T 12-10-2018 NPD12_697 98033b903fd2a68efa761019c80198f0 221 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_697 98033b903fd2a68efa761019c80198f0 221 SUPERFAMILY SSF52540 3 220 2.35E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 Gene3D G3DSA:2.40.50.140 1 77 1.2E-16 T 12-10-2018 NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 SUPERFAMILY SSF53335 67 449 8.01E-78 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 SUPERFAMILY SSF50249 2 56 4.4E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 433 443 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 Gene3D G3DSA:3.40.1350.30 125 285 3.6E-114 T 12-10-2018 NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 Pfam PF01938 TRAM domain 3 57 5.1E-7 T 12-10-2018 IPR002792 TRAM domain NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 443 1.3E-105 T 12-10-2018 NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 87 450 8.6E-26 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 NPD12_2914 6cf0517b246c2039c60e5b2bbeaa3098 450 Gene3D G3DSA:3.40.50.150 79 445 3.6E-114 T 12-10-2018 NPD12_431 1cb489c0fee9e72f2d905fb116150b5c 188 SUPERFAMILY SSF52833 50 186 6.91E-36 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_431 1cb489c0fee9e72f2d905fb116150b5c 188 Gene3D G3DSA:3.40.30.10 25 188 3.5E-44 T 12-10-2018 NPD12_431 1cb489c0fee9e72f2d905fb116150b5c 188 Pfam PF00578 AhpC/TSA family 49 168 1.3E-24 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 NPD12_1854 9250260ce114d50421440d4fa60dde89 408 Gene3D G3DSA:1.20.1250.20 2 395 5.2E-55 T 12-10-2018 NPD12_1854 9250260ce114d50421440d4fa60dde89 408 SUPERFAMILY SSF103473 4 397 3.27E-60 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_1854 9250260ce114d50421440d4fa60dde89 408 Pfam PF07690 Major Facilitator Superfamily 12 291 1.6E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_1854 9250260ce114d50421440d4fa60dde89 408 Pfam PF07690 Major Facilitator Superfamily 295 393 3.5E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 32.62 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 Gene3D G3DSA:3.30.70.660 107 244 3.7E-46 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 4 239 1.5E-56 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 PIRSF PIRSF001430 1 246 4.5E-73 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 Gene3D G3DSA:3.30.70.580 1 106 1.1E-30 T 12-10-2018 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 SUPERFAMILY SSF55120 1 245 4.32E-75 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 Pfam PF01416 tRNA pseudouridine synthase 9 87 2.1E-5 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_2079 20f7a81e802e098fc185668d70df859e 246 Pfam PF01416 tRNA pseudouridine synthase 144 246 2.9E-25 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 NPD12_1598 2ea30250de14e2a7fc8663eac3548fbf 221 SUPERFAMILY SSF52540 3 219 5.45E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1598 2ea30250de14e2a7fc8663eac3548fbf 221 Gene3D G3DSA:3.40.50.300 1 221 2.5E-64 T 12-10-2018 NPD12_1598 2ea30250de14e2a7fc8663eac3548fbf 221 SMART SM00382 30 215 4.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1598 2ea30250de14e2a7fc8663eac3548fbf 221 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1598 2ea30250de14e2a7fc8663eac3548fbf 221 Pfam PF00005 ABC transporter 21 167 5.8E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 Gene3D G3DSA:3.40.50.12160 1 134 7.6E-23 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 425 3.2E-135 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 Gene3D G3DSA:3.80.30.20 139 374 9.3E-88 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 SMART SM00729 142 360 1.2E-55 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 5 416 9.7E-141 T 12-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 Pfam PF00919 Uncharacterized protein family UPF0004 2 97 2.4E-25 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 146 166 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 Pfam PF04055 Radical SAM superfamily 148 318 1.1E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3004 0ca1dcc249a87f195b3105c1f35b7bd4 432 SUPERFAMILY SSF102114 116 364 1.96E-57 T 12-10-2018 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 Gene3D G3DSA:2.40.50.530 1 64 1.1E-24 T 12-10-2018 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 9.4E-28 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-20 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-20 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-20 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.936 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 Pfam PF01632 Ribosomal protein L35 2 62 3.1E-26 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3244 998a0d701676fda7cc58740a95b7fa28 65 SUPERFAMILY SSF143034 2 64 1.07E-24 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_861 67784271c642e80d8a178904e04f8772 273 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 250 1.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_861 67784271c642e80d8a178904e04f8772 273 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 266 1.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_861 67784271c642e80d8a178904e04f8772 273 SMART SM00342 183 266 9.6E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_861 67784271c642e80d8a178904e04f8772 273 SUPERFAMILY SSF51215 27 152 5.89E-5 T 12-10-2018 IPR037923 Transcription regulator HTH-like NPD12_861 67784271c642e80d8a178904e04f8772 273 Gene3D G3DSA:1.10.10.60 164 271 1.7E-27 T 12-10-2018 NPD12_861 67784271c642e80d8a178904e04f8772 273 Pfam PF12833 Helix-turn-helix domain 189 267 1.5E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_861 67784271c642e80d8a178904e04f8772 273 SUPERFAMILY SSF46689 220 270 6.72E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_456 5f160408b88a815d01ae15e62bd34b29 157 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 9 132 3.1E-46 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_456 5f160408b88a815d01ae15e62bd34b29 157 Gene3D G3DSA:2.70.70.10 3 157 1.1E-50 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_456 5f160408b88a815d01ae15e62bd34b29 157 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 10 131 3.7E-41 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_456 5f160408b88a815d01ae15e62bd34b29 157 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 73 85 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_456 5f160408b88a815d01ae15e62bd34b29 157 SUPERFAMILY SSF51261 3 147 3.31E-49 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_2043 73f043768d752cfd821fd5589e690c86 567 SUPERFAMILY SSF52540 1 509 1.39E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2043 73f043768d752cfd821fd5589e690c86 567 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 554 5.5E-157 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 NPD12_2043 73f043768d752cfd821fd5589e690c86 567 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 509 2.0E-16 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal NPD12_2043 73f043768d752cfd821fd5589e690c86 567 PIRSF PIRSF003128 1 559 2.2E-163 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 NPD12_2043 73f043768d752cfd821fd5589e690c86 567 Gene3D G3DSA:3.40.50.300 1 224 2.0E-39 T 12-10-2018 NPD12_2043 73f043768d752cfd821fd5589e690c86 567 Gene3D G3DSA:3.40.50.300 252 555 2.0E-50 T 12-10-2018 NPD12_2110 1530f8ccd143120e361110465bc180d6 230 Gene3D G3DSA:3.40.50.300 1 230 3.4E-60 T 12-10-2018 NPD12_2110 1530f8ccd143120e361110465bc180d6 230 SMART SM00382 27 205 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2110 1530f8ccd143120e361110465bc180d6 230 Pfam PF00005 ABC transporter 23 157 1.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2110 1530f8ccd143120e361110465bc180d6 230 SUPERFAMILY SSF52540 3 221 1.52E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 Gene3D G3DSA:3.40.50.300 166 444 7.6E-110 T 12-10-2018 NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 SUPERFAMILY SSF48024 6 118 6.67E-34 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 Pfam PF00772 DnaB-like helicase N terminal domain 8 109 8.3E-33 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 SMART SM00382 200 379 4.6E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 Gene3D G3DSA:1.10.860.10 4 164 2.6E-54 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 SUPERFAMILY SSF52540 181 431 1.19E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 8 439 3.3E-177 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 NPD12_99 1edb6a8aa75bc9778d34eb9ec0f01623 445 Pfam PF03796 DnaB-like helicase C terminal domain 183 438 3.8E-114 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 NPD12_885 de53260dad04ce123f6fe05f1ff86b09 162 Pfam PF01047 MarR family 34 91 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_885 de53260dad04ce123f6fe05f1ff86b09 162 Gene3D G3DSA:1.10.10.10 2 146 3.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_885 de53260dad04ce123f6fe05f1ff86b09 162 SUPERFAMILY SSF46785 16 148 1.07E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_885 de53260dad04ce123f6fe05f1ff86b09 162 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 99 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site NPD12_885 de53260dad04ce123f6fe05f1ff86b09 162 SMART SM00347 26 129 1.4E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_21 f92765e13f10c3e245ded50be62600b9 449 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 120 131 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_21 f92765e13f10c3e245ded50be62600b9 449 Gene3D G3DSA:3.30.70.20 78 143 1.6E-10 T 12-10-2018 NPD12_21 f92765e13f10c3e245ded50be62600b9 449 SUPERFAMILY SSF54862 94 139 5.35E-14 T 12-10-2018 NPD12_21 f92765e13f10c3e245ded50be62600b9 449 Pfam PF00037 4Fe-4S binding domain 114 135 8.3E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_21 f92765e13f10c3e245ded50be62600b9 449 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 154 390 1.5E-60 T 12-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal NPD12_21 f92765e13f10c3e245ded50be62600b9 449 SUPERFAMILY SSF53920 119 427 8.5E-75 T 12-10-2018 IPR009016 Iron hydrogenase NPD12_21 f92765e13f10c3e245ded50be62600b9 449 Gene3D G3DSA:3.40.950.20 191 433 1.7E-38 T 12-10-2018 NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 SMART SM00387 216 326 1.5E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 325 1.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 1.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 1.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 1.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 Gene3D G3DSA:3.30.565.10 169 323 2.8E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 SUPERFAMILY SSF55874 164 324 6.15E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 Gene3D G3DSA:1.10.287.130 119 168 2.8E-29 T 12-10-2018 NPD12_483 07ef58838e49ba61d7d61ae336977f59 326 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 218 323 1.8E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2390 397b576fb624799bdc9f310abbd98e29 333 SUPERFAMILY SSF56235 91 312 4.24E-17 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_2390 397b576fb624799bdc9f310abbd98e29 333 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 98 319 3.8E-36 T 12-10-2018 IPR005079 Peptidase C45 NPD12_2390 397b576fb624799bdc9f310abbd98e29 333 Gene3D G3DSA:3.60.60.10 81 329 1.3E-42 T 12-10-2018 NPD12_923 b275d68d418d02b0aa3c6e04ed9b88a3 140 SMART SM00530 6 62 4.2E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_923 b275d68d418d02b0aa3c6e04ed9b88a3 140 SUPERFAMILY SSF47413 1 64 4.02E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_923 b275d68d418d02b0aa3c6e04ed9b88a3 140 Pfam PF01381 Helix-turn-helix 8 62 1.2E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_923 b275d68d418d02b0aa3c6e04ed9b88a3 140 Gene3D G3DSA:1.10.260.40 3 139 6.2E-19 T 12-10-2018 NPD12_2609 5eba329c18f6a3f61fbd00868c48db9c 83 Pfam PF06135 Bacterial protein of unknown function (DUF965) 4 80 1.2E-34 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 NPD12_2609 5eba329c18f6a3f61fbd00868c48db9c 83 PIRSF PIRSF037258 1 83 4.2E-37 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 NPD12_2609 5eba329c18f6a3f61fbd00868c48db9c 83 Hamap MF_01507 UPF0297 protein . 1 83 23.014 T 12-10-2018 IPR009309 Uncharacterised protein family UPF0297 NPD12_827 c3d79599b9fa3c32f79269a4ccc631c5 132 Gene3D G3DSA:3.90.79.10 1 131 3.9E-33 T 12-10-2018 NPD12_827 c3d79599b9fa3c32f79269a4ccc631c5 132 PRINTS PR00502 NUDIX hydrolase family signature 34 48 6.0E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_827 c3d79599b9fa3c32f79269a4ccc631c5 132 PRINTS PR00502 NUDIX hydrolase family signature 48 63 6.0E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_827 c3d79599b9fa3c32f79269a4ccc631c5 132 SUPERFAMILY SSF55811 2 128 1.0E-31 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 NPD12_827 c3d79599b9fa3c32f79269a4ccc631c5 132 Pfam PF00293 NUDIX domain 6 122 1.7E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 NPD12_632 13cfec7c9336d2a8d33a7520ee8f68c4 297 Gene3D G3DSA:3.90.79.10 6 133 1.9E-20 T 12-10-2018 NPD12_632 13cfec7c9336d2a8d33a7520ee8f68c4 297 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 NPD12_632 13cfec7c9336d2a8d33a7520ee8f68c4 297 SUPERFAMILY SSF55811 5 105 4.87E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 NPD12_632 13cfec7c9336d2a8d33a7520ee8f68c4 297 Pfam PF00293 NUDIX domain 8 104 1.2E-12 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 NPD12_632 13cfec7c9336d2a8d33a7520ee8f68c4 297 PRINTS PR00502 NUDIX hydrolase family signature 33 47 7.9E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_632 13cfec7c9336d2a8d33a7520ee8f68c4 297 PRINTS PR00502 NUDIX hydrolase family signature 47 62 7.9E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_319 7b52aa98cc9122db4c97eb5149c97a9c 174 SUPERFAMILY SSF53163 8 171 1.07E-44 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily NPD12_319 7b52aa98cc9122db4c97eb5149c97a9c 174 Pfam PF06866 Protein of unknown function (DUF1256) 6 163 1.7E-63 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 NPD12_319 7b52aa98cc9122db4c97eb5149c97a9c 174 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 28 165 1.9E-46 T 12-10-2018 IPR009665 Protein of unknown function DUF1256 NPD12_2325 b4b913c5553f0041da77c7242d16976d 199 Gene3D G3DSA:3.40.109.10 2 199 1.3E-87 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_2325 b4b913c5553f0041da77c7242d16976d 199 SUPERFAMILY SSF55469 4 197 6.67E-69 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_2325 b4b913c5553f0041da77c7242d16976d 199 Pfam PF00881 Nitroreductase family 9 178 2.5E-17 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_2752 0ae776ededf79f104548e0f27027be6d 365 Gene3D G3DSA:3.40.640.10 1 242 7.3E-99 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2752 0ae776ededf79f104548e0f27027be6d 365 SUPERFAMILY SSF53383 2 364 1.88E-118 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2752 0ae776ededf79f104548e0f27027be6d 365 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 2 347 6.0E-130 T 12-10-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family NPD12_2752 0ae776ededf79f104548e0f27027be6d 365 Gene3D G3DSA:3.90.1150.10 244 365 1.0E-27 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_2752 0ae776ededf79f104548e0f27027be6d 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 10 362 1.7E-115 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_2752 0ae776ededf79f104548e0f27027be6d 365 PIRSF PIRSF000390 1 365 1.6E-109 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 269 275 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 Pfam PF12161 HsdM N-terminal domain 6 130 3.5E-11 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 6.2E-17 T 12-10-2018 NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 320 6.2E-17 T 12-10-2018 NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 266 278 6.2E-17 T 12-10-2018 NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 159 175 6.2E-17 T 12-10-2018 NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 Pfam PF02384 N-6 DNA Methylase 137 450 3.8E-69 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 Gene3D G3DSA:3.40.50.150 162 469 5.9E-79 T 12-10-2018 NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 Gene3D G3DSA:1.20.1260.30 1 161 3.3E-29 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily NPD12_856 ecbdb77eaf83a14624cc74620f6d8374 485 SUPERFAMILY SSF53335 5 484 4.48E-126 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2342 1cec1670976276c7a1feae15a2984fa8 113 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 17.533 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 NPD12_2342 1cec1670976276c7a1feae15a2984fa8 113 PIRSF PIRSF004761 1 113 2.9E-25 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 NPD12_2342 1cec1670976276c7a1feae15a2984fa8 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 3.4E-25 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 NPD12_2342 1cec1670976276c7a1feae15a2984fa8 113 Gene3D G3DSA:3.30.2320.80 1 112 6.0E-26 T 12-10-2018 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 Gene3D G3DSA:3.30.70.1400 53 139 5.0E-93 T 12-10-2018 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 SUPERFAMILY SSF103025 3 284 1.13E-102 T 12-10-2018 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 PIRSF PIRSF006487 1 370 7.0E-109 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 Gene3D G3DSA:2.40.30.110 283 365 2.1E-28 T 12-10-2018 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 SUPERFAMILY SSF101790 276 366 3.27E-24 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 365 46.337 T 12-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 Pfam PF01571 Aminomethyltransferase folate-binding domain 13 261 8.4E-99 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 363 1.2E-130 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 Gene3D G3DSA:4.10.1250.10 240 281 1.5E-17 T 12-10-2018 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 Gene3D G3DSA:3.30.1360.120 7 238 5.0E-93 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 NPD12_871 e4c5521dcfdf2beb12229216d732ebb6 370 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 358 1.0E-27 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 Gene3D G3DSA:3.40.50.2030 251 399 7.9E-71 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 Gene3D G3DSA:1.20.1270.20 1 165 6.3E-44 T 12-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 3 568 1.3E-240 T 12-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 Gene3D G3DSA:1.20.1270.20 166 249 1.1E-33 T 12-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 Hamap MF_00069 Hydroxylamine reductase [hcp]. 3 570 24.301 T 12-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 Gene3D G3DSA:3.40.50.2030 400 569 1.9E-64 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 PIRSF PIRSF000076 3 570 4.4E-273 T 12-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 Pfam PF03063 Prismane/CO dehydrogenase family 3 566 2.4E-188 T 12-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 NPD12_2825 633e0e26583aa660e1bc45ed88db77b5 570 SUPERFAMILY SSF56821 3 569 4.27E-213 T 12-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 NPD12_2180 5aadd6f7dfede1c12267e1d7400f9aa4 221 PIRSF PIRSF000440 1 217 1.9E-75 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_2180 5aadd6f7dfede1c12267e1d7400f9aa4 221 SMART SM01059 1 208 4.0E-110 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_2180 5aadd6f7dfede1c12267e1d7400f9aa4 221 Pfam PF00302 Chloramphenicol acetyltransferase 3 208 1.2E-79 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_2180 5aadd6f7dfede1c12267e1d7400f9aa4 221 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 13 207 2.0E-67 T 12-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 NPD12_2180 5aadd6f7dfede1c12267e1d7400f9aa4 221 SUPERFAMILY SSF52777 1 213 3.71E-68 T 12-10-2018 NPD12_2180 5aadd6f7dfede1c12267e1d7400f9aa4 221 Gene3D G3DSA:3.30.559.10 2 211 4.2E-67 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 Gene3D G3DSA:2.60.40.10 450 542 2.8E-23 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 Gene3D G3DSA:3.20.20.80 36 449 1.1E-144 T 12-10-2018 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00841 Bacterial beta-amylase signature 411 432 4.0E-27 T 12-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00841 Bacterial beta-amylase signature 244 261 4.0E-27 T 12-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00841 Bacterial beta-amylase signature 135 154 4.0E-27 T 12-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00841 Bacterial beta-amylase signature 228 243 4.0E-27 T 12-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 Pfam PF00686 Starch binding domain 449 538 7.1E-16 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 SMART SM01065 448 541 8.9E-18 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 Pfam PF01373 Glycosyl hydrolase family 14 45 440 5.2E-161 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 90 108 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 373 395 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 69 83 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 112 133 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 336 359 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 324 335 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 268 287 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 305 321 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 194 216 8.4E-57 T 12-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 NPD12_1389 18273a06f3a724cbd99d50fe678722fc 542 SUPERFAMILY SSF51445 37 500 5.05E-136 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 Gene3D G3DSA:3.90.190.20 319 459 1.9E-42 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 Gene3D G3DSA:3.40.1190.10 89 317 1.5E-63 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 SUPERFAMILY SSF63418 2 105 5.1E-22 T 12-10-2018 IPR035911 MurE/MurF, N-terminal NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 397 7.8E-15 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 457 33.847 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 Pfam PF01225 Mur ligase family, catalytic domain 26 103 1.4E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 SUPERFAMILY SSF53244 321 456 1.36E-34 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 Pfam PF08245 Mur ligase middle domain 113 299 3.7E-48 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 SUPERFAMILY SSF53623 107 317 1.44E-50 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 456 8.6E-127 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_1708 bfaeaedf1599a64854fac0cf30868e2b 462 Gene3D G3DSA:3.40.1390.10 1 80 5.5E-22 T 12-10-2018 NPD12_1041 606b92f4269465a862396c33ac22ea9a 209 Gene3D G3DSA:3.40.109.10 1 206 1.1E-55 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_1041 606b92f4269465a862396c33ac22ea9a 209 Pfam PF00881 Nitroreductase family 8 184 9.2E-24 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_1041 606b92f4269465a862396c33ac22ea9a 209 SUPERFAMILY SSF55469 4 203 3.27E-46 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 Pfam PF13181 Tetratricopeptide repeat 147 176 0.14 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 Pfam PF13181 Tetratricopeptide repeat 180 209 1.9E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 SUPERFAMILY SSF48452 79 210 3.07E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 Gene3D G3DSA:1.25.40.10 9 222 9.3E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 SMART SM00028 77 110 89.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 SMART SM00028 145 178 0.02 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 SMART SM00028 111 144 1.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3598 68e81ceb5afdd5e15ccd5679482f6a20 235 SMART SM00028 179 211 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00145 Argininosuccinate lyase family signature 192 208 4.4E-61 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00145 Argininosuccinate lyase family signature 230 254 4.4E-61 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 4.4E-61 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00145 Argininosuccinate lyase family signature 274 290 4.4E-61 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00145 Argininosuccinate lyase family signature 309 328 4.4E-61 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00145 Argininosuccinate lyase family signature 141 161 4.4E-61 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 431 1.2E-179 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 Gene3D G3DSA:1.20.200.10 119 358 2.7E-179 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 Gene3D G3DSA:1.10.275.10 25 228 2.7E-179 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 ProSitePatterns PS00163 Fumarate lyases signature. 274 283 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 428 40.076 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 Gene3D G3DSA:1.10.40.30 359 431 2.7E-179 T 12-10-2018 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 Pfam PF14698 Argininosuccinate lyase C-terminal 362 430 4.7E-22 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00149 Fumarate lyase superfamily signature 230 257 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00149 Fumarate lyase superfamily signature 274 290 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 Pfam PF00206 Lyase 6 299 3.2E-74 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal NPD12_2718 4ac83832ff11c5e4b9213354fadeceda 440 SUPERFAMILY SSF48557 3 430 2.36E-134 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 NPD12_373 2ae74a4a0045bca6e3b95bcb25e224df 450 Pfam PF07501 G5 domain 382 449 1.6E-15 T 12-10-2018 IPR011098 G5 domain NPD12_373 2ae74a4a0045bca6e3b95bcb25e224df 450 SMART SM01208 373 450 2.2E-20 T 12-10-2018 IPR011098 G5 domain NPD12_373 2ae74a4a0045bca6e3b95bcb25e224df 450 Pfam PF04294 VanW like protein 236 365 7.4E-50 T 12-10-2018 IPR007391 Vancomycin resistance VanW NPD12_373 2ae74a4a0045bca6e3b95bcb25e224df 450 Pfam PF12229 Putative peptidoglycan binding domain 83 192 6.0E-23 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain NPD12_373 2ae74a4a0045bca6e3b95bcb25e224df 450 Gene3D G3DSA:2.20.230.10 378 450 7.0E-13 T 12-10-2018 NPD12_1829 9cb8340786ea9fa616cf4dfc17621097 216 Pfam PF03006 Haemolysin-III related 6 206 1.2E-47 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 NPD12_1829 9cb8340786ea9fa616cf4dfc17621097 216 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 8 213 8.5E-65 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 NPD12_419 2a81eb52782381757a3d3e6b8070fc16 224 Pfam PF00857 Isochorismatase family 65 202 1.3E-28 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 NPD12_419 2a81eb52782381757a3d3e6b8070fc16 224 Gene3D G3DSA:3.40.50.850 112 211 5.7E-19 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 NPD12_419 2a81eb52782381757a3d3e6b8070fc16 224 Gene3D G3DSA:3.40.50.850 39 111 5.2E-7 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 NPD12_419 2a81eb52782381757a3d3e6b8070fc16 224 SUPERFAMILY SSF52499 48 203 6.15E-29 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 250 2.7E-16 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 Pfam PF00037 4Fe-4S binding domain 58 80 5.4E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 Pfam PF00037 4Fe-4S binding domain 92 110 2.9E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 Gene3D G3DSA:3.40.50.300 2 63 8.8E-8 T 12-10-2018 NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 SUPERFAMILY SSF52540 3 273 7.06E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 Gene3D G3DSA:3.30.70.20 64 125 1.1E-9 T 12-10-2018 NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 SUPERFAMILY SSF54862 47 119 6.02E-17 T 12-10-2018 NPD12_2346 2c480defbc9cec79b545afa2f0883140 276 Gene3D G3DSA:3.40.50.300 136 275 5.7E-17 T 12-10-2018 NPD12_3699 5d974b11efd63157919c5d970abc63c2 181 SUPERFAMILY SSF53271 4 181 1.88E-59 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_3699 5d974b11efd63157919c5d970abc63c2 181 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 11 175 1.5E-68 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 NPD12_3699 5d974b11efd63157919c5d970abc63c2 181 Pfam PF00156 Phosphoribosyl transferase domain 17 162 5.6E-27 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_3699 5d974b11efd63157919c5d970abc63c2 181 Gene3D G3DSA:3.40.50.2020 3 181 1.1E-68 T 12-10-2018 NPD12_1277 c69011c5d621fb104f8cb1407ba1ede2 155 SUPERFAMILY SSF55729 15 144 2.4E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1277 c69011c5d621fb104f8cb1407ba1ede2 155 Pfam PF00583 Acetyltransferase (GNAT) family 16 132 6.9E-10 T 12-10-2018 IPR000182 GNAT domain NPD12_1277 c69011c5d621fb104f8cb1407ba1ede2 155 Gene3D G3DSA:3.40.630.30 1 153 5.1E-26 T 12-10-2018 NPD12_467 f007d76af3b68f075f7dc7716c054a4b 343 SUPERFAMILY SSF53807 65 340 2.2E-40 T 12-10-2018 NPD12_467 f007d76af3b68f075f7dc7716c054a4b 343 Gene3D G3DSA:3.40.50.1980 29 198 1.3E-36 T 12-10-2018 NPD12_467 f007d76af3b68f075f7dc7716c054a4b 343 Gene3D G3DSA:3.40.50.1980 201 342 5.8E-19 T 12-10-2018 NPD12_467 f007d76af3b68f075f7dc7716c054a4b 343 Pfam PF01497 Periplasmic binding protein 74 312 2.0E-21 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_3469 13451450b9abbcc8e74d17360437af90 378 Pfam PF12679 ABC-2 family transporter protein 6 376 4.3E-20 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_1157 e33f55b1e190f08df5ca9cb36d7fd130 152 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 134 1.5E-17 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_3433 d8b2911a68932e3e0ad4a483e2c1c8fb 296 Pfam PF00175 Oxidoreductase NAD-binding domain 110 204 2.2E-6 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 NPD12_3433 d8b2911a68932e3e0ad4a483e2c1c8fb 296 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 257 7.7E-13 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain NPD12_3433 d8b2911a68932e3e0ad4a483e2c1c8fb 296 Gene3D G3DSA:2.40.30.10 1 91 1.5E-24 T 12-10-2018 NPD12_3433 d8b2911a68932e3e0ad4a483e2c1c8fb 296 SUPERFAMILY SSF52343 104 256 8.91E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_3433 d8b2911a68932e3e0ad4a483e2c1c8fb 296 SUPERFAMILY SSF63380 1 91 1.51E-20 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel NPD12_3433 d8b2911a68932e3e0ad4a483e2c1c8fb 296 PIRSF PIRSF006816 1 263 2.4E-68 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 NPD12_3433 d8b2911a68932e3e0ad4a483e2c1c8fb 296 Gene3D G3DSA:3.40.50.80 107 211 6.3E-36 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain NPD12_403 3bb003b4d0db3983336cf7b0babb450d 250 Gene3D G3DSA:3.30.70.20 176 239 1.3E-11 T 12-10-2018 NPD12_403 3bb003b4d0db3983336cf7b0babb450d 250 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 216 227 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_403 3bb003b4d0db3983336cf7b0babb450d 250 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_403 3bb003b4d0db3983336cf7b0babb450d 250 SUPERFAMILY SSF54862 163 240 1.44E-14 T 12-10-2018 NPD12_403 3bb003b4d0db3983336cf7b0babb450d 250 Gene3D G3DSA:3.40.50.360 3 128 2.3E-5 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_403 3bb003b4d0db3983336cf7b0babb450d 250 SUPERFAMILY SSF52218 4 110 2.1E-10 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2820 0cd2bd6330fc3f425a00f81f36443e66 232 Pfam PF04892 VanZ like family 45 181 1.7E-22 T 12-10-2018 IPR006976 VanZ-like NPD12_2320 25193e042bb56d8d7ebff68c6aa47707 272 SUPERFAMILY SSF52218 4 158 5.99E-18 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2320 25193e042bb56d8d7ebff68c6aa47707 272 Pfam PF13746 4Fe-4S dicluster domain 192 240 1.2E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2320 25193e042bb56d8d7ebff68c6aa47707 272 SUPERFAMILY SSF54862 199 257 9.21E-15 T 12-10-2018 NPD12_2320 25193e042bb56d8d7ebff68c6aa47707 272 Gene3D G3DSA:3.30.70.20 197 247 5.0E-7 T 12-10-2018 NPD12_2320 25193e042bb56d8d7ebff68c6aa47707 272 Gene3D G3DSA:3.40.50.360 4 155 3.4E-13 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2320 25193e042bb56d8d7ebff68c6aa47707 272 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 202 213 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_1981 dc844eec072f2a7594ecfb49ba6392ed 389 Gene3D G3DSA:3.60.40.10 1 225 9.2E-28 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_1981 dc844eec072f2a7594ecfb49ba6392ed 389 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 32 216 2.0E-14 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_1981 dc844eec072f2a7594ecfb49ba6392ed 389 SMART SM00331 4 218 9.0E-4 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_1981 dc844eec072f2a7594ecfb49ba6392ed 389 SUPERFAMILY SSF81606 5 217 3.14E-10 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_1047 8591d2a7645c72ff29cc0932ff8aa270 148 Pfam PF13673 Acetyltransferase (GNAT) domain 54 139 6.0E-14 T 12-10-2018 IPR000182 GNAT domain NPD12_1047 8591d2a7645c72ff29cc0932ff8aa270 148 SUPERFAMILY SSF55729 9 143 2.66E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1047 8591d2a7645c72ff29cc0932ff8aa270 148 Gene3D G3DSA:3.40.630.30 6 148 7.8E-29 T 12-10-2018 NPD12_705 e1855b44b7aa0360b13d46dae556c697 169 SUPERFAMILY SSF51161 2 164 4.02E-46 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_705 e1855b44b7aa0360b13d46dae556c697 169 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 10 44 0.002 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_705 e1855b44b7aa0360b13d46dae556c697 169 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 1.8E-9 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_705 e1855b44b7aa0360b13d46dae556c697 169 Gene3D G3DSA:2.160.10.10 1 169 8.9E-62 T 12-10-2018 NPD12_1262 5f6279b34e0f7cb2a768b5696cb06c8d 472 Pfam PF01266 FAD dependent oxidoreductase 3 354 1.3E-64 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 NPD12_1262 5f6279b34e0f7cb2a768b5696cb06c8d 472 Pfam PF04324 BFD-like [2Fe-2S] binding domain 398 452 2.6E-18 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain NPD12_1262 5f6279b34e0f7cb2a768b5696cb06c8d 472 SUPERFAMILY SSF51905 1 407 2.03E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1262 5f6279b34e0f7cb2a768b5696cb06c8d 472 Gene3D G3DSA:1.10.10.1100 384 461 1.6E-24 T 12-10-2018 NPD12_1262 5f6279b34e0f7cb2a768b5696cb06c8d 472 Gene3D G3DSA:3.50.50.60 3 349 3.1E-124 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1262 5f6279b34e0f7cb2a768b5696cb06c8d 472 Gene3D G3DSA:3.30.9.10 86 315 3.1E-124 T 12-10-2018 NPD12_917 28353cd7eb11870c891acaef8b7d62c2 257 SUPERFAMILY SSF53335 54 247 6.66E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_917 28353cd7eb11870c891acaef8b7d62c2 257 Pfam PF08241 Methyltransferase domain 66 162 5.0E-19 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 NPD12_917 28353cd7eb11870c891acaef8b7d62c2 257 Gene3D G3DSA:3.40.50.150 55 256 2.9E-29 T 12-10-2018 NPD12_96 9d7ec91951b92384180ab52881f701aa 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.2E-5 T 12-10-2018 NPD12_96 9d7ec91951b92384180ab52881f701aa 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 411 433 4.2E-5 T 12-10-2018 NPD12_96 9d7ec91951b92384180ab52881f701aa 461 Gene3D G3DSA:3.50.50.60 1 96 7.0E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_96 9d7ec91951b92384180ab52881f701aa 461 Gene3D G3DSA:3.50.50.60 107 235 9.8E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_96 9d7ec91951b92384180ab52881f701aa 461 SUPERFAMILY SSF51905 2 457 9.61E-23 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_96 9d7ec91951b92384180ab52881f701aa 461 PIRSF PIRSF038984 1 88 1.6E-10 T 12-10-2018 IPR028348 FAD dependent protein NPD12_96 9d7ec91951b92384180ab52881f701aa 461 PIRSF PIRSF038984 114 460 9.0E-20 T 12-10-2018 IPR028348 FAD dependent protein NPD12_1622 321df965d699875d306020487a19f42f 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 318 3.3E-34 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1622 321df965d699875d306020487a19f42f 318 Gene3D G3DSA:1.10.3720.10 90 312 1.6E-13 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1622 321df965d699875d306020487a19f42f 318 SUPERFAMILY SSF161098 96 305 1.07E-10 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2391 727d83f1d3a61ad889f7d6d73581bb4f 193 Pfam PF03358 NADPH-dependent FMN reductase 1 132 2.1E-24 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_2391 727d83f1d3a61ad889f7d6d73581bb4f 193 SUPERFAMILY SSF52218 1 188 9.78E-36 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2391 727d83f1d3a61ad889f7d6d73581bb4f 193 Gene3D G3DSA:3.40.50.360 2 193 4.6E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2473 9bfc0794bcb84244eccba02219b2287f 336 Pfam PF13180 PDZ domain 119 181 4.4E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_2473 9bfc0794bcb84244eccba02219b2287f 336 SUPERFAMILY SSF50156 79 182 2.76E-16 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 NPD12_2473 9bfc0794bcb84244eccba02219b2287f 336 Pfam PF02163 Peptidase family M50 6 321 3.5E-78 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 NPD12_2473 9bfc0794bcb84244eccba02219b2287f 336 SMART SM00228 102 174 9.7E-5 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_2473 9bfc0794bcb84244eccba02219b2287f 336 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 117 331 3.5E-50 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 NPD12_2473 9bfc0794bcb84244eccba02219b2287f 336 Gene3D G3DSA:2.30.42.10 117 200 1.6E-21 T 12-10-2018 NPD12_3534 f3fe773ddc837f18214a93734c864109 243 Hamap MF_01561 Probable phosphatase YcdX [ycdX]. 2 243 45.947 T 12-10-2018 IPR023710 Probable phosphatase YcdX GO:0008270 NPD12_3534 f3fe773ddc837f18214a93734c864109 243 Gene3D G3DSA:3.20.20.140 3 242 1.3E-64 T 12-10-2018 NPD12_3534 f3fe773ddc837f18214a93734c864109 243 SMART SM00481 5 79 2.0E-11 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal NPD12_3534 f3fe773ddc837f18214a93734c864109 243 Pfam PF02811 PHP domain 6 148 5.1E-6 T 12-10-2018 IPR004013 PHP domain GO:0003824 NPD12_3534 f3fe773ddc837f18214a93734c864109 243 SUPERFAMILY SSF89550 4 236 1.83E-56 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_2940 b23a2e7de9153617f301f2e2d3c64884 403 SUPERFAMILY SSF53686 22 397 1.83E-58 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme NPD12_2940 b23a2e7de9153617f301f2e2d3c64884 403 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 42 380 1.5E-49 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme NPD12_2940 b23a2e7de9153617f301f2e2d3c64884 403 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 4 399 9.0E-218 T 12-10-2018 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 NPD12_2940 b23a2e7de9153617f301f2e2d3c64884 403 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 24 398 1.7E-185 T 12-10-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 NPD12_2940 b23a2e7de9153617f301f2e2d3c64884 403 Gene3D G3DSA:3.40.50.1100 76 198 1.3E-148 T 12-10-2018 NPD12_2940 b23a2e7de9153617f301f2e2d3c64884 403 Gene3D G3DSA:3.40.50.1100 33 396 1.3E-148 T 12-10-2018 NPD12_3826 f758ef6e67f8a4390f993c6496676bcb 296 Pfam PF01446 Replication protein 136 238 3.2E-9 T 12-10-2018 IPR000989 Replication protein GO:0003677|GO:0005727|GO:0006260 NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 Gene3D G3DSA:3.40.50.300 328 577 6.8E-85 T 12-10-2018 NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 SUPERFAMILY SSF90123 10 320 1.7E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 Pfam PF00005 ABC transporter 353 500 1.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 Gene3D G3DSA:1.20.1560.10 1 324 9.4E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 SUPERFAMILY SSF52540 330 569 3.28E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 Pfam PF00664 ABC transporter transmembrane region 22 292 5.1E-26 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_1841 5923ae71f4d3641d4e0f8feb1b28391e 584 SMART SM00382 361 552 3.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1079 41a997b8662bf0908a570a8e58d2873f 125 Gene3D G3DSA:2.40.440.10 8 125 8.5E-46 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_1079 41a997b8662bf0908a570a8e58d2873f 125 SUPERFAMILY SSF141523 16 124 1.83E-37 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_1079 41a997b8662bf0908a570a8e58d2873f 125 Pfam PF03734 L,D-transpeptidase catalytic domain 16 124 4.1E-22 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 NPD12_3273 7e750e85ab9622de5dd12b18acd84edc 294 Gene3D G3DSA:2.130.10.10 184 294 2.1E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 NPD12_3273 7e750e85ab9622de5dd12b18acd84edc 294 Gene3D G3DSA:2.130.10.10 1 183 4.7E-25 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 NPD12_3273 7e750e85ab9622de5dd12b18acd84edc 294 SUPERFAMILY SSF50969 5 285 1.41E-30 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 Gene3D G3DSA:1.10.287.950 308 667 1.0E-64 T 12-10-2018 NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 SMART SM00283 392 667 1.4E-56 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 Pfam PF02743 Cache domain 48 268 6.2E-29 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 Gene3D G3DSA:3.30.450.20 50 277 9.9E-45 T 12-10-2018 NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 460 618 4.9E-34 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 Gene3D G3DSA:3.30.450.20 63 174 9.9E-45 T 12-10-2018 NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 SUPERFAMILY SSF58104 339 666 6.41E-63 T 12-10-2018 NPD12_3323 bd95993ea7cda333da08517fdb8d539b 668 SUPERFAMILY SSF103190 71 184 7.85E-14 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 Pfam PF07729 FCD domain 98 222 3.7E-23 T 12-10-2018 IPR011711 GntR, C-terminal NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 Gene3D G3DSA:1.10.10.10 3 80 1.8E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 SUPERFAMILY SSF46785 4 77 5.96E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 7.9E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 SMART SM00345 14 73 3.5E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 Gene3D G3DSA:1.20.120.530 95 230 7.1E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 SMART SM00895 98 223 6.7E-17 T 12-10-2018 IPR011711 GntR, C-terminal NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.6E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.6E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1285 526382fd921e637da0283e4c9c2e4bc6 230 SUPERFAMILY SSF48008 96 227 2.04E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal NPD12_343 893645deaea53b1b2ca915291b807cae 813 SUPERFAMILY SSF50677 224 408 1.05E-54 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Gene3D G3DSA:1.10.730.10 593 749 6.4E-43 T 12-10-2018 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Pfam PF09334 tRNA synthetases class I (M) 40 180 1.5E-17 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 410 605 1.1E-20 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_343 893645deaea53b1b2ca915291b807cae 813 SUPERFAMILY SSF52374 7 618 4.73E-139 T 12-10-2018 NPD12_343 893645deaea53b1b2ca915291b807cae 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 8.9E-50 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 8.9E-50 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 553 563 8.9E-50 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 8.9E-50 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 520 542 8.9E-50 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 481 499 8.9E-50 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 8.9E-50 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 397 5.6E-66 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Gene3D G3DSA:2.30.210.10 568 582 3.7E-251 T 12-10-2018 NPD12_343 893645deaea53b1b2ca915291b807cae 813 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 813 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Gene3D G3DSA:3.10.20.590 751 813 2.7E-18 T 12-10-2018 NPD12_343 893645deaea53b1b2ca915291b807cae 813 SUPERFAMILY SSF47323 638 812 3.18E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Gene3D G3DSA:3.90.740.10 226 408 3.7E-251 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 812 21.73 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Pfam PF08264 Anticodon-binding domain of tRNA 658 776 2.5E-22 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 NPD12_343 893645deaea53b1b2ca915291b807cae 813 Gene3D G3DSA:3.40.50.620 32 567 3.7E-251 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_878 0f028883c93976d6a96c44be077b7172 184 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 6.2E-28 T 12-10-2018 IPR000182 GNAT domain NPD12_878 0f028883c93976d6a96c44be077b7172 184 SUPERFAMILY SSF55729 1 156 3.15E-38 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_878 0f028883c93976d6a96c44be077b7172 184 Gene3D G3DSA:3.40.630.30 1 181 3.1E-42 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 SUPERFAMILY SSF54211 547 741 1.29E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 660 679 7.2E-12 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 690 708 7.2E-12 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 549 565 7.2E-12 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 630 649 7.2E-12 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 Gene3D G3DSA:3.40.50.300 34 164 4.1E-7 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 Gene3D G3DSA:3.40.50.300 202 439 4.7E-48 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 544 739 4.8E-16 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 Pfam PF13654 AAA domain 35 524 1.5E-111 T 12-10-2018 NPD12_1690 1ceb1c5631b76cb62c70f80606ecacb9 772 Gene3D G3DSA:3.30.230.10 525 764 1.2E-89 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_2735 d2b03488285274e1a623dc15914ee743 234 Gene3D G3DSA:3.40.50.300 2 229 2.6E-81 T 12-10-2018 NPD12_2735 d2b03488285274e1a623dc15914ee743 234 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 39 229 2.0E-18 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 NPD12_2735 d2b03488285274e1a623dc15914ee743 234 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 19 223 2.0E-71 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 NPD12_2735 d2b03488285274e1a623dc15914ee743 234 SUPERFAMILY SSF52540 39 221 9.18E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1792 0b2ce66c911bff54850c8edf2b172794 331 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 9 325 1.5E-32 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_1792 0b2ce66c911bff54850c8edf2b172794 331 Gene3D G3DSA:3.40.50.11900 211 330 4.2E-10 T 12-10-2018 NPD12_1271 5b9a30f1b5a3869c8b07c90bbc06c619 587 Pfam PF07664 Ferrous iron transport protein B C terminus 382 434 3.1E-21 T 12-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 NPD12_1271 5b9a30f1b5a3869c8b07c90bbc06c619 587 Gene3D G3DSA:3.40.50.300 3 195 1.9E-43 T 12-10-2018 NPD12_1271 5b9a30f1b5a3869c8b07c90bbc06c619 587 Pfam PF02421 Ferrous iron transport protein B 3 153 1.0E-60 T 12-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 NPD12_1271 5b9a30f1b5a3869c8b07c90bbc06c619 587 Pfam PF07670 Nucleoside recognition 278 369 6.6E-15 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_1271 5b9a30f1b5a3869c8b07c90bbc06c619 587 Pfam PF07670 Nucleoside recognition 439 558 7.0E-34 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_1271 5b9a30f1b5a3869c8b07c90bbc06c619 587 SUPERFAMILY SSF52540 1 157 2.24E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1271 5b9a30f1b5a3869c8b07c90bbc06c619 587 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 192 555 6.8E-124 T 12-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 NPD12_2880 4f8d55cc8425c3ce3054c8793dcc5df4 303 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 6 218 1.2E-88 T 12-10-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 NPD12_2880 4f8d55cc8425c3ce3054c8793dcc5df4 303 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 6 303 7.9E-112 T 12-10-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 NPD12_247 2461c3183ee8b2adff15cf5b36f0cd6f 356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 207 353 7.1E-37 T 12-10-2018 IPR000160 GGDEF domain NPD12_247 2461c3183ee8b2adff15cf5b36f0cd6f 356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 205 352 6.6E-37 T 12-10-2018 IPR000160 GGDEF domain NPD12_247 2461c3183ee8b2adff15cf5b36f0cd6f 356 SUPERFAMILY SSF55073 212 352 8.63E-36 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_247 2461c3183ee8b2adff15cf5b36f0cd6f 356 Gene3D G3DSA:3.30.70.270 198 354 1.0E-40 T 12-10-2018 NPD12_247 2461c3183ee8b2adff15cf5b36f0cd6f 356 SUPERFAMILY SSF55781 36 202 1.42E-9 T 12-10-2018 NPD12_247 2461c3183ee8b2adff15cf5b36f0cd6f 356 SMART SM00267 196 355 8.6E-39 T 12-10-2018 IPR000160 GGDEF domain NPD12_247 2461c3183ee8b2adff15cf5b36f0cd6f 356 Gene3D G3DSA:3.30.450.40 32 196 3.4E-12 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_2998 5268fda66004ac33aad6fa6bb3e21738 695 Pfam PF07698 7TM receptor with intracellular HD hydrolase 268 453 7.2E-45 T 12-10-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain NPD12_2998 5268fda66004ac33aad6fa6bb3e21738 695 SUPERFAMILY SSF109604 477 678 4.08E-15 T 12-10-2018 NPD12_2998 5268fda66004ac33aad6fa6bb3e21738 695 Gene3D G3DSA:1.10.3210.10 410 652 3.0E-20 T 12-10-2018 NPD12_2998 5268fda66004ac33aad6fa6bb3e21738 695 Pfam PF01966 HD domain 478 622 1.0E-16 T 12-10-2018 IPR006674 HD domain NPD12_2998 5268fda66004ac33aad6fa6bb3e21738 695 SMART SM00471 474 632 7.2E-10 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_2998 5268fda66004ac33aad6fa6bb3e21738 695 TIGRFAM TIGR00277 HDIG: HDIG domain 475 573 6.3E-22 T 12-10-2018 IPR006675 HDIG domain NPD12_2998 5268fda66004ac33aad6fa6bb3e21738 695 Pfam PF07697 7TM-HD extracellular 44 260 9.9E-40 T 12-10-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain NPD12_2597 737ca370a0fa50b7ad3ed68ffc422a51 267 Pfam PF12684 PDDEXK-like domain of unknown function (DUF3799) 19 255 5.3E-86 T 12-10-2018 IPR024432 Putative exodeoxyribonuclease 8, PDDEXK-like domain NPD12_2597 737ca370a0fa50b7ad3ed68ffc422a51 267 Gene3D G3DSA:3.90.320.10 1 267 7.6E-88 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal NPD12_3320 8380812ed115ff3c4405fd9ff9954682 154 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 8 147 4.0E-30 T 12-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 NPD12_3320 8380812ed115ff3c4405fd9ff9954682 154 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 142 7.2E-26 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 NPD12_3320 8380812ed115ff3c4405fd9ff9954682 154 Gene3D G3DSA:3.60.21.10 1 151 7.9E-39 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like NPD12_3320 8380812ed115ff3c4405fd9ff9954682 154 SUPERFAMILY SSF56300 10 149 6.96E-31 T 12-10-2018 NPD12_370 2b9602f4409553ddcb5dae147903fc95 327 Gene3D G3DSA:3.40.50.1820 70 326 4.8E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_370 2b9602f4409553ddcb5dae147903fc95 327 Pfam PF09752 Abhydrolase domain containing 18 262 322 9.2E-5 T 12-10-2018 IPR019149 Abhydrolase domain containing 18 NPD12_370 2b9602f4409553ddcb5dae147903fc95 327 Pfam PF12146 Serine aminopeptidase, S33 98 189 5.7E-8 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 NPD12_370 2b9602f4409553ddcb5dae147903fc95 327 SUPERFAMILY SSF53474 39 325 1.16E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2018 d54ce3eddc4efa09758c7efc21f8d1a5 291 Pfam PF00589 Phage integrase family 108 275 2.4E-40 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 NPD12_2018 d54ce3eddc4efa09758c7efc21f8d1a5 291 Gene3D G3DSA:1.10.150.130 2 94 1.1E-21 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal NPD12_2018 d54ce3eddc4efa09758c7efc21f8d1a5 291 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 291 8.9E-103 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 NPD12_2018 d54ce3eddc4efa09758c7efc21f8d1a5 291 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 85 2.6E-16 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 NPD12_2018 d54ce3eddc4efa09758c7efc21f8d1a5 291 SUPERFAMILY SSF56349 2 280 4.71E-52 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 NPD12_2018 d54ce3eddc4efa09758c7efc21f8d1a5 291 Gene3D G3DSA:1.10.443.10 107 282 1.7E-52 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 NPD12_2206 33ade48274f210c80b8f2e24db499c5e 214 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 124 151 8.8E-5 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_2206 33ade48274f210c80b8f2e24db499c5e 214 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 163 194 2.7E-4 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_2206 33ade48274f210c80b8f2e24db499c5e 214 Gene3D G3DSA:2.160.10.10 91 214 1.1E-29 T 12-10-2018 NPD12_2206 33ade48274f210c80b8f2e24db499c5e 214 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 4 209 3.9E-66 T 12-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like NPD12_2206 33ade48274f210c80b8f2e24db499c5e 214 Gene3D G3DSA:3.40.50.20 1 90 1.6E-20 T 12-10-2018 NPD12_2206 33ade48274f210c80b8f2e24db499c5e 214 SUPERFAMILY SSF51161 1 212 1.8E-39 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_2688 5fda4c2756df3baa3356b2b0e0cfabde 255 Pfam PF00460 Flagella basal body rod protein 5 35 1.7E-10 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 NPD12_2688 5fda4c2756df3baa3356b2b0e0cfabde 255 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 140 2.3E-36 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G NPD12_2688 5fda4c2756df3baa3356b2b0e0cfabde 255 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 249 5.6E-18 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain NPD12_2688 5fda4c2756df3baa3356b2b0e0cfabde 255 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site NPD12_2688 5fda4c2756df3baa3356b2b0e0cfabde 255 SUPERFAMILY SSF117143 92 212 2.09E-22 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 SUPERFAMILY SSF47384 470 547 4.32E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 Gene3D G3DSA:3.30.565.10 552 697 3.0E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 Pfam PF00512 His Kinase A (phospho-acceptor) domain 482 547 1.0E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 600 685 1.3E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 648 658 4.2E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 681 4.2E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 SMART SM00388 481 547 3.7E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 SMART SM00387 593 700 6.5E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 SUPERFAMILY SSF55874 550 685 3.46E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1852 f7e3600f8a1b74e6eedba63219453961 700 Gene3D G3DSA:1.10.287.130 461 550 1.7E-19 T 12-10-2018 NPD12_3202 f531f7fbe8bddddfa025003ea80228d0 217 Pfam PF02397 Bacterial sugar transferase 24 211 6.8E-68 T 12-10-2018 IPR003362 Bacterial sugar transferase NPD12_3202 f531f7fbe8bddddfa025003ea80228d0 217 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 5 216 1.3E-89 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase NPD12_2474 7c6be4a2064ead975be685991249dce7 385 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 229 2.8E-40 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 SUPERFAMILY SSF69055 291 381 3.4E-28 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 Gene3D G3DSA:1.10.1740.10 303 383 1.1E-23 T 12-10-2018 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 7.0E-42 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 Pfam PF13288 DXP reductoisomerase C-terminal domain 261 377 4.2E-42 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 SUPERFAMILY SSF55347 126 264 2.94E-61 T 12-10-2018 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 Gene3D G3DSA:3.40.50.720 1 150 9.7E-50 T 12-10-2018 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 PIRSF PIRSF006205 1 384 8.3E-161 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 379 6.7E-153 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 NPD12_2474 7c6be4a2064ead975be685991249dce7 385 SUPERFAMILY SSF51735 2 150 3.64E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2474 7c6be4a2064ead975be685991249dce7 385 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 382 47.233 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 SMART SM00388 194 261 4.5E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 SUPERFAMILY SSF47384 178 257 1.03E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 SMART SM00387 304 416 2.1E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 SMART SM00304 122 193 0.0083 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 195 258 1.6E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 415 3.3E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 Gene3D G3DSA:1.10.287.130 126 261 3.3E-24 T 12-10-2018 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 414 1.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 1.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 395 1.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 370 1.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 Gene3D G3DSA:3.30.565.10 263 416 1.7E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2437 52b2ecdaba46b59e4a51b4d8c454bca2 416 SUPERFAMILY SSF55874 250 415 3.41E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 SUPERFAMILY SSF56784 511 663 8.71E-20 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 Pfam PF00122 E1-E2 ATPase 113 304 1.6E-34 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 60 74 4.8E-5 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 445 463 4.8E-5 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 318 339 4.8E-5 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 SUPERFAMILY SSF81653 119 222 1.02E-23 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 SUPERFAMILY SSF81660 336 525 2.4E-35 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 69 2.0E-9 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 620 639 5.1E-8 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 5.1E-8 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 518 529 5.1E-8 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 325 339 5.1E-8 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 Gene3D G3DSA:1.20.1110.10 55 853 8.1E-123 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 Gene3D G3DSA:3.40.1110.10 335 525 8.1E-123 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 Pfam PF13246 Cation transport ATPase (P-type) 376 461 1.6E-15 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 SUPERFAMILY SSF81665 3 856 4.84E-41 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 Gene3D G3DSA:2.70.150.10 16 228 8.1E-123 T 12-10-2018 NPD12_3020 b4aa2d869f15861a2b1e19d3100911ff 864 Gene3D G3DSA:3.40.50.1000 322 663 8.1E-123 T 12-10-2018 IPR023214 HAD superfamily NPD12_109 2830e4d1dca0e24100c5c11d3eaee9d3 65 PIRSF PIRSF037263 1 65 1.8E-34 T 12-10-2018 IPR009296 Protein of unknown function DUF951 NPD12_109 2830e4d1dca0e24100c5c11d3eaee9d3 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 5 58 3.2E-31 T 12-10-2018 IPR009296 Protein of unknown function DUF951 NPD12_1196 7f3e94a769c20a6074904db819b5e600 424 Pfam PF09861 Domain of unknown function (DUF2088) 8 213 3.8E-78 T 12-10-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 NPD12_1196 7f3e94a769c20a6074904db819b5e600 424 Gene3D G3DSA:3.90.226.30 6 418 3.6E-163 T 12-10-2018 NPD12_1196 7f3e94a769c20a6074904db819b5e600 424 Gene3D G3DSA:3.40.50.11440 34 269 3.6E-163 T 12-10-2018 NPD12_2028 9a98bb01e11583a5f7b230c38d7a6101 177 Pfam PF14470 Bacterial PH domain 33 123 2.7E-20 T 12-10-2018 IPR039519 YokE-like, PH domain NPD12_2028 9a98bb01e11583a5f7b230c38d7a6101 177 Pfam PF09851 Short C-terminal domain 147 174 1.9E-7 T 12-10-2018 IPR018649 SHOCT domain NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 91 1.8E-42 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 PIRSF PIRSF002144 1 94 6.8E-32 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 Gene3D G3DSA:3.30.860.10 1 92 6.7E-38 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 SUPERFAMILY SSF54570 2 84 2.35E-34 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 Pfam PF00203 Ribosomal protein S19 3 83 7.9E-35 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.155 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 9.0E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 9.0E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3635 2514188877adb4e9a1fad45dd8d48c21 94 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 9.0E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_1916 0838c7283c9727dd28ea8ead69475011 211 Pfam PF08241 Methyltransferase domain 51 150 6.7E-20 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 NPD12_1916 0838c7283c9727dd28ea8ead69475011 211 SUPERFAMILY SSF53335 26 201 7.5E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_1916 0838c7283c9727dd28ea8ead69475011 211 Gene3D G3DSA:3.40.50.150 19 209 3.7E-37 T 12-10-2018 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 287 40.794 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 Gene3D G3DSA:3.90.226.10 34 288 6.7E-93 T 12-10-2018 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 23 287 1.0E-125 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 Pfam PF01039 Carboxyl transferase domain 69 248 2.5E-23 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 135 149 1.4E-41 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 206 223 1.4E-41 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 235 246 1.4E-41 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 169 187 1.4E-41 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 257 266 1.4E-41 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 NPD12_64 d2aaa4b0b6b25b59a2798600b5f617be 289 SUPERFAMILY SSF52096 34 287 1.49E-82 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 6 466 17.326 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 6 507 1.0E-105 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 PIRSF PIRSF002869 1 512 4.5E-121 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 Pfam PF03023 MviN-like protein 31 466 7.5E-90 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 PRINTS PR01806 Virulence factor MviN signature 36 55 9.4E-17 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 PRINTS PR01806 Virulence factor MviN signature 258 284 9.4E-17 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 PRINTS PR01806 Virulence factor MviN signature 134 158 9.4E-17 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 PRINTS PR01806 Virulence factor MviN signature 356 375 9.4E-17 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 PRINTS PR01806 Virulence factor MviN signature 158 179 9.4E-17 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3204 d2bb81f0459bc2c905a0516f9be3bd33 518 PRINTS PR01806 Virulence factor MviN signature 408 425 9.4E-17 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Pfam PF00271 Helicase conserved C-terminal domain 433 543 3.8E-18 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Gene3D G3DSA:3.40.50.300 413 594 3.7E-52 T 12-10-2018 NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Gene3D G3DSA:3.40.50.300 1 236 3.1E-80 T 12-10-2018 NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Gene3D G3DSA:3.40.50.300 270 412 1.9E-52 T 12-10-2018 NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Pfam PF04851 Type III restriction enzyme, res subunit 10 138 3.8E-13 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Pfam PF02151 UvrB/uvrC motif 622 656 2.2E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 SUPERFAMILY SSF52540 1 413 3.93E-141 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 SUPERFAMILY SSF46600 610 656 1.19E-11 T 12-10-2018 IPR036876 UVR domain superfamily NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Pfam PF12344 Ultra-violet resistance protein B 550 592 1.1E-22 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 657 43.367 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 SUPERFAMILY SSF52540 36 579 1.56E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 SMART SM00487 8 424 1.8E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 Gene3D G3DSA:4.10.860.10 602 658 1.1E-7 T 12-10-2018 NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 SMART SM00490 458 544 1.2E-20 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_3542 5a320ad24a6968ae5849357dd0878257 662 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 3 655 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 NPD12_1733 69fb268435a8dbcdbada05a76ab7300e 223 Gene3D G3DSA:1.10.3720.10 1 219 3.9E-59 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1733 69fb268435a8dbcdbada05a76ab7300e 223 SUPERFAMILY SSF161098 2 211 4.58E-50 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1733 69fb268435a8dbcdbada05a76ab7300e 223 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 7 214 5.4E-72 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 NPD12_1733 69fb268435a8dbcdbada05a76ab7300e 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 22 209 4.7E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_3094 e1d00c3df9839139f675358d6047dfca 108 Gene3D G3DSA:3.30.70.1490 1 107 6.4E-32 T 12-10-2018 IPR036764 Cysteine protease Prp superfamily NPD12_3094 e1d00c3df9839139f675358d6047dfca 108 SUPERFAMILY SSF118010 1 108 1.31E-31 T 12-10-2018 IPR036764 Cysteine protease Prp superfamily NPD12_3094 e1d00c3df9839139f675358d6047dfca 108 Pfam PF04327 Cysteine protease Prp 1 102 2.0E-26 T 12-10-2018 IPR007422 Cysteine protease Prp NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 Gene3D G3DSA:4.10.910.10 73 123 2.6E-24 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 4.3E-54 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 Pfam PF00416 Ribosomal protein S13/S18 3 109 9.1E-32 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 Gene3D G3DSA:1.10.8.50 1 72 2.1E-31 T 12-10-2018 NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 PIRSF PIRSF002134 1 123 1.4E-43 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 SUPERFAMILY SSF46946 2 121 1.96E-45 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 NPD12_3613 39c69c6a7a7bd7335e8f4455b4b7d351 123 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.137 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_184 35a1fd3000f1d75028d280dd9020653b 198 Pfam PF03167 Uracil DNA glycosylase superfamily 29 191 4.6E-36 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_184 35a1fd3000f1d75028d280dd9020653b 198 SMART SM00986 28 189 4.9E-24 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_184 35a1fd3000f1d75028d280dd9020653b 198 SMART SM00987 28 189 4.9E-24 T 12-10-2018 NPD12_184 35a1fd3000f1d75028d280dd9020653b 198 Gene3D G3DSA:3.40.470.10 2 198 6.6E-45 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_184 35a1fd3000f1d75028d280dd9020653b 198 SUPERFAMILY SSF52141 16 196 8.83E-42 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_3236 adb8e0bce09b67e51df949bfd2bb7218 153 Pfam PF00535 Glycosyl transferase family 2 7 117 2.1E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_3236 adb8e0bce09b67e51df949bfd2bb7218 153 SUPERFAMILY SSF53448 6 138 4.58E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_3236 adb8e0bce09b67e51df949bfd2bb7218 153 Gene3D G3DSA:3.90.550.10 4 149 1.4E-21 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2658 5ca646018efd9ac11fcaa418e59c4085 381 Pfam PF02754 Cysteine-rich domain 137 216 2.3E-7 T 12-10-2018 IPR004017 Cysteine-rich domain NPD12_2658 5ca646018efd9ac11fcaa418e59c4085 381 Pfam PF02754 Cysteine-rich domain 254 332 4.9E-8 T 12-10-2018 IPR004017 Cysteine-rich domain NPD12_2658 5ca646018efd9ac11fcaa418e59c4085 381 SUPERFAMILY SSF46548 6 94 2.96E-13 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_2658 5ca646018efd9ac11fcaa418e59c4085 381 Pfam PF13183 4Fe-4S dicluster domain 22 78 8.5E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2658 5ca646018efd9ac11fcaa418e59c4085 381 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2658 5ca646018efd9ac11fcaa418e59c4085 381 Gene3D G3DSA:3.30.70.20 2 83 4.2E-6 T 12-10-2018 NPD12_1350 3a0ca91871891a6f5016ed30420b3282 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 267 1.3E-28 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 NPD12_244 5ebef907d9ef4c15e0c2706bd0a4fb89 280 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 29 274 1.2E-90 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 NPD12_244 5ebef907d9ef4c15e0c2706bd0a4fb89 280 SUPERFAMILY SSF52540 25 257 9.96E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_244 5ebef907d9ef4c15e0c2706bd0a4fb89 280 ProSitePatterns PS01215 Mrp family signature. 143 159 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 NPD12_244 5ebef907d9ef4c15e0c2706bd0a4fb89 280 Gene3D G3DSA:3.40.50.300 21 279 1.0E-69 T 12-10-2018 NPD12_244 5ebef907d9ef4c15e0c2706bd0a4fb89 280 Hamap MF_02040 Iron-sulfur cluster carrier protein. 22 273 33.613 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein NPD12_2904 de712864b3847d6160abb69e418aee67 247 Pfam PF12833 Helix-turn-helix domain 161 234 2.4E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2904 de712864b3847d6160abb69e418aee67 247 Gene3D G3DSA:1.10.10.60 135 238 2.2E-15 T 12-10-2018 NPD12_2904 de712864b3847d6160abb69e418aee67 247 SMART SM00342 155 237 1.6E-9 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_3634 448625c942122d9b72ca9099cb6ae643 111 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 5.6E-42 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3634 448625c942122d9b72ca9099cb6ae643 111 Gene3D G3DSA:3.90.470.10 1 111 1.6E-47 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3634 448625c942122d9b72ca9099cb6ae643 111 SUPERFAMILY SSF54843 1 110 7.19E-44 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3634 448625c942122d9b72ca9099cb6ae643 111 Pfam PF00237 Ribosomal protein L22p/L17e 6 108 9.2E-37 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 NPD12_3634 448625c942122d9b72ca9099cb6ae643 111 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3634 448625c942122d9b72ca9099cb6ae643 111 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.513 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_474 a8c4663fe7ecc6c11e976f3060e3dfd2 309 Gene3D G3DSA:3.40.50.1980 22 141 2.0E-19 T 12-10-2018 NPD12_474 a8c4663fe7ecc6c11e976f3060e3dfd2 309 Gene3D G3DSA:3.40.50.1980 142 308 2.7E-40 T 12-10-2018 NPD12_474 a8c4663fe7ecc6c11e976f3060e3dfd2 309 Pfam PF01497 Periplasmic binding protein 98 279 9.9E-19 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_474 a8c4663fe7ecc6c11e976f3060e3dfd2 309 SUPERFAMILY SSF53807 35 299 3.02E-39 T 12-10-2018 NPD12_1100 71e963d730cc2d11457b726e5237abda 362 Gene3D G3DSA:3.90.1150.10 19 357 2.2E-104 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1100 71e963d730cc2d11457b726e5237abda 362 Pfam PF00155 Aminotransferase class I and II 16 355 8.6E-35 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1100 71e963d730cc2d11457b726e5237abda 362 SUPERFAMILY SSF53383 11 360 3.84E-65 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1100 71e963d730cc2d11457b726e5237abda 362 Gene3D G3DSA:3.40.640.10 29 265 2.2E-104 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1794 8a4aebf0de09771f1d73353e1d89aaf3 143 SUPERFAMILY SSF55620 1 138 2.06E-33 T 12-10-2018 NPD12_1794 8a4aebf0de09771f1d73353e1d89aaf3 143 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 139 7.8E-33 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 NPD12_1794 8a4aebf0de09771f1d73353e1d89aaf3 143 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 116 1.7E-29 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 NPD12_1794 8a4aebf0de09771f1d73353e1d89aaf3 143 Gene3D G3DSA:3.30.479.10 83 143 2.5E-9 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 NPD12_1794 8a4aebf0de09771f1d73353e1d89aaf3 143 Gene3D G3DSA:3.30.479.10 1 82 5.2E-21 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 NPD12_1794 8a4aebf0de09771f1d73353e1d89aaf3 143 PIRSF PIRSF006113 1 84 7.1E-16 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 NPD12_1794 8a4aebf0de09771f1d73353e1d89aaf3 143 PIRSF PIRSF006113 93 140 0.017 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 Gene3D G3DSA:1.20.1480.50 156 249 6.3E-11 T 12-10-2018 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 SUPERFAMILY SSF103190 44 165 2.67E-13 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 Pfam PF00672 HAMP domain 191 236 5.8E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 SMART SM00304 191 243 5.3E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 SMART SM00283 272 547 3.0E-61 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 Pfam PF17203 Single cache domain 3 63 165 1.3E-6 T 12-10-2018 IPR033463 Single cache domain 3 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 319 478 5.3E-40 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 Gene3D G3DSA:3.30.450.20 43 153 3.4E-8 T 12-10-2018 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 SUPERFAMILY SSF58104 211 545 2.88E-63 T 12-10-2018 NPD12_2161 b0485f0adcfea92989c4e4de1cd154c0 549 Gene3D G3DSA:1.10.287.950 255 547 9.9E-61 T 12-10-2018 NPD12_3267 c7a3fa5905b94c5f3c82e1503110d0ab 387 Gene3D G3DSA:3.90.1150.10 33 380 9.8E-121 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_3267 c7a3fa5905b94c5f3c82e1503110d0ab 387 Pfam PF00155 Aminotransferase class I and II 33 379 5.1E-67 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_3267 c7a3fa5905b94c5f3c82e1503110d0ab 387 SUPERFAMILY SSF53383 10 384 3.82E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_3267 c7a3fa5905b94c5f3c82e1503110d0ab 387 Gene3D G3DSA:3.40.640.10 63 283 9.8E-121 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_3267 c7a3fa5905b94c5f3c82e1503110d0ab 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 15 89 2.1E-22 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 SMART SM00967 15 90 5.4E-22 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 Pfam PF00588 SpoU rRNA Methylase family 107 247 7.6E-40 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 Gene3D G3DSA:3.40.1280.10 88 254 1.1E-55 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 SUPERFAMILY SSF55315 13 87 1.79E-17 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 Gene3D G3DSA:3.30.1330.30 4 86 1.2E-14 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 14 253 7.8E-81 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 NPD12_3660 4d274402fe97451ccb3fba5dcd676517 257 SUPERFAMILY SSF75217 78 254 1.5E-48 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases NPD12_2936 62637d45549355dbc6117385264d480b 1005 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 803 821 3.2E-12 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_2936 62637d45549355dbc6117385264d480b 1005 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 541 563 3.2E-12 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_2936 62637d45549355dbc6117385264d480b 1005 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 665 689 3.2E-12 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_2936 62637d45549355dbc6117385264d480b 1005 SUPERFAMILY SSF51395 45 399 2.12E-10 T 12-10-2018 NPD12_2936 62637d45549355dbc6117385264d480b 1005 SUPERFAMILY SSF51971 539 775 1.29E-43 T 12-10-2018 NPD12_2936 62637d45549355dbc6117385264d480b 1005 Gene3D G3DSA:3.50.50.60 543 831 2.7E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2936 62637d45549355dbc6117385264d480b 1005 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 444 520 1.5E-14 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 NPD12_2936 62637d45549355dbc6117385264d480b 1005 SUPERFAMILY SSF46548 871 945 1.73E-7 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_2936 62637d45549355dbc6117385264d480b 1005 Gene3D G3DSA:1.10.1060.10 416 542 3.8E-20 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_2936 62637d45549355dbc6117385264d480b 1005 SUPERFAMILY SSF46548 444 550 2.98E-16 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_2936 62637d45549355dbc6117385264d480b 1005 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 669 687 3.0E-17 T 12-10-2018 NPD12_2936 62637d45549355dbc6117385264d480b 1005 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 793 815 3.0E-17 T 12-10-2018 NPD12_2936 62637d45549355dbc6117385264d480b 1005 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 542 561 3.0E-17 T 12-10-2018 NPD12_2936 62637d45549355dbc6117385264d480b 1005 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 766 782 3.0E-17 T 12-10-2018 NPD12_2936 62637d45549355dbc6117385264d480b 1005 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 540 828 3.0E-35 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_2936 62637d45549355dbc6117385264d480b 1005 SUPERFAMILY SSF51971 754 831 8.12E-7 T 12-10-2018 NPD12_2936 62637d45549355dbc6117385264d480b 1005 Gene3D G3DSA:3.50.50.60 636 774 2.7E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2936 62637d45549355dbc6117385264d480b 1005 TIGRFAM TIGR03315 Se_ygfK: putative selenate reductase, YgfK subunit 2 1005 0.0 T 12-10-2018 IPR017701 Putative selenate reductase YgfK NPD12_2936 62637d45549355dbc6117385264d480b 1005 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 918 929 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2979 1b6b0d345c4536ed7601f94f02034cd9 417 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 104 342 2.4E-25 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 NPD12_2979 1b6b0d345c4536ed7601f94f02034cd9 417 Gene3D G3DSA:3.40.640.10 75 314 1.7E-54 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2979 1b6b0d345c4536ed7601f94f02034cd9 417 SUPERFAMILY SSF53383 76 413 1.93E-62 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2979 1b6b0d345c4536ed7601f94f02034cd9 417 Gene3D G3DSA:3.90.1150.10 315 412 2.5E-7 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_3692 67bba212c070c998b872e36a9c712205 504 PIRSF PIRSF039101 2 504 4.5E-200 T 12-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 2.0E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 2.0E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 2.0E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 382 398 2.0E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 2.0E-39 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 Pfam PF01336 OB-fold nucleic acid binding domain 63 139 2.3E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 NPD12_3692 67bba212c070c998b872e36a9c712205 504 Gene3D G3DSA:3.30.930.10 152 504 9.8E-135 T 12-10-2018 NPD12_3692 67bba212c070c998b872e36a9c712205 504 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 497 9.6E-83 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3692 67bba212c070c998b872e36a9c712205 504 Gene3D G3DSA:2.40.50.140 15 149 2.3E-41 T 12-10-2018 NPD12_3692 67bba212c070c998b872e36a9c712205 504 SUPERFAMILY SSF50249 14 149 1.05E-40 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3692 67bba212c070c998b872e36a9c712205 504 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 500 44.734 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 15 500 6.6E-205 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3692 67bba212c070c998b872e36a9c712205 504 SUPERFAMILY SSF55681 156 498 4.27E-121 T 12-10-2018 NPD12_3287 9443f5e67f387338efbb44aef3fcd85f 409 Pfam PF05193 Peptidase M16 inactive domain 166 328 5.4E-30 T 12-10-2018 IPR007863 Peptidase M16, C-terminal NPD12_3287 9443f5e67f387338efbb44aef3fcd85f 409 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 34 57 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 NPD12_3287 9443f5e67f387338efbb44aef3fcd85f 409 Gene3D G3DSA:3.30.830.10 227 409 2.9E-27 T 12-10-2018 NPD12_3287 9443f5e67f387338efbb44aef3fcd85f 409 SUPERFAMILY SSF63411 3 208 7.33E-56 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_3287 9443f5e67f387338efbb44aef3fcd85f 409 Pfam PF00675 Insulinase (Peptidase family M16) 19 159 1.7E-33 T 12-10-2018 IPR011765 Peptidase M16, N-terminal NPD12_3287 9443f5e67f387338efbb44aef3fcd85f 409 Gene3D G3DSA:3.30.830.10 5 213 2.0E-67 T 12-10-2018 NPD12_3287 9443f5e67f387338efbb44aef3fcd85f 409 SUPERFAMILY SSF63411 230 405 1.17E-28 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_3261 fe16c7f8bbbcb40e1e14261c9e8b5b2c 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 305 4.9E-33 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_3261 fe16c7f8bbbcb40e1e14261c9e8b5b2c 305 Gene3D G3DSA:1.10.3720.10 93 305 1.3E-23 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3261 fe16c7f8bbbcb40e1e14261c9e8b5b2c 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 75 1.0E-17 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain NPD12_3261 fe16c7f8bbbcb40e1e14261c9e8b5b2c 305 SUPERFAMILY SSF161098 98 287 3.01E-27 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2486 51fb0111366dac446fa2f305e9b05a90 361 Pfam PF02481 DNA recombination-mediator protein A 73 278 1.2E-77 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 NPD12_2486 51fb0111366dac446fa2f305e9b05a90 361 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 285 4.4E-74 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 NPD12_2486 51fb0111366dac446fa2f305e9b05a90 361 Gene3D G3DSA:3.40.50.450 7 294 8.9E-94 T 12-10-2018 NPD12_2486 51fb0111366dac446fa2f305e9b05a90 361 SUPERFAMILY SSF102405 81 287 2.38E-36 T 12-10-2018 NPD12_542 da4bc346397aa87244d4174b125ea8e2 1351 Gene3D G3DSA:2.60.40.1220 856 952 1.4E-8 T 12-10-2018 NPD12_542 da4bc346397aa87244d4174b125ea8e2 1351 Gene3D G3DSA:2.60.40.1220 638 739 5.4E-6 T 12-10-2018 NPD12_542 da4bc346397aa87244d4174b125ea8e2 1351 Gene3D G3DSA:2.60.40.1220 747 850 1.1E-5 T 12-10-2018 NPD12_542 da4bc346397aa87244d4174b125ea8e2 1351 Pfam PF04122 Putative cell wall binding repeat 2 37 123 7.0E-20 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_542 da4bc346397aa87244d4174b125ea8e2 1351 Pfam PF04122 Putative cell wall binding repeat 2 136 226 8.0E-13 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_542 da4bc346397aa87244d4174b125ea8e2 1351 Pfam PF04122 Putative cell wall binding repeat 2 238 328 6.3E-16 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_542 da4bc346397aa87244d4174b125ea8e2 1351 Gene3D G3DSA:3.40.50.12090 59 153 5.2E-13 T 12-10-2018 NPD12_3150 39444ef065211f4654bfeefa3b359f3e 70 Pfam PF01381 Helix-turn-helix 7 61 1.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3150 39444ef065211f4654bfeefa3b359f3e 70 SUPERFAMILY SSF47413 7 64 6.48E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3150 39444ef065211f4654bfeefa3b359f3e 70 SMART SM00530 5 61 5.4E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3150 39444ef065211f4654bfeefa3b359f3e 70 Gene3D G3DSA:1.10.260.40 2 68 3.4E-12 T 12-10-2018 NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 30 38 2.1E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 100 114 2.1E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 57 68 2.1E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 PIRSF PIRSF005539 1 293 7.1E-100 T 12-10-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 SUPERFAMILY SSF53474 12 291 1.09E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 Gene3D G3DSA:3.40.50.1820 1 292 5.4E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 Pfam PF00561 alpha/beta hydrolase fold 28 276 1.3E-30 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_2190 f635896ea2e72734b3366a712c10cff4 293 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 3 290 1.0E-88 T 12-10-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 Gene3D G3DSA:3.40.50.2300 165 297 2.4E-26 T 12-10-2018 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 SMART SM00260 11 144 3.5E-17 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 PIRSF PIRSF002867 1 297 9.5E-93 T 12-10-2018 IPR024181 Chemotaxis response regulator CheV NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 SUPERFAMILY SSF50341 5 148 1.31E-31 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 Gene3D G3DSA:2.30.30.40 17 138 7.9E-27 T 12-10-2018 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 SMART SM00448 169 292 7.6E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 Pfam PF01584 CheW-like domain 16 146 1.6E-25 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 Gene3D G3DSA:2.40.50.180 32 144 7.9E-27 T 12-10-2018 NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 SUPERFAMILY SSF52172 165 296 1.11E-25 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1929 a33212bed5dee0e90c2d7ae64182a0e8 297 Pfam PF00072 Response regulator receiver domain 171 292 2.6E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1520 c0931e777c51357379a955ecba1e68bd 215 SUPERFAMILY SSF53639 4 210 3.34E-52 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily NPD12_1520 c0931e777c51357379a955ecba1e68bd 215 Gene3D G3DSA:3.40.225.10 2 213 7.8E-62 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily NPD12_1520 c0931e777c51357379a955ecba1e68bd 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 184 4.1E-43 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal NPD12_1520 c0931e777c51357379a955ecba1e68bd 215 SMART SM01007 9 186 4.7E-56 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal NPD12_1040 bcf05897f69aed11e18548f2615801c1 102 SUPERFAMILY SSF46785 4 101 5.77E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1040 bcf05897f69aed11e18548f2615801c1 102 Pfam PF01638 HxlR-like helix-turn-helix 16 101 2.0E-33 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type NPD12_1040 bcf05897f69aed11e18548f2615801c1 102 Gene3D G3DSA:1.10.10.10 2 102 1.9E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2394 f914f781891e4fb4a12d0ae20bc06dce 62 Pfam PF12788 YmaF family 8 55 2.2E-13 T 12-10-2018 IPR024307 YmaF NPD12_2456 30cb66de98d4d249ee47c970d68695d1 230 SUPERFAMILY SSF52096 28 215 6.26E-38 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily NPD12_2456 30cb66de98d4d249ee47c970d68695d1 230 Pfam PF00574 Clp protease 38 207 8.6E-29 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA NPD12_2456 30cb66de98d4d249ee47c970d68695d1 230 Gene3D G3DSA:3.90.226.10 35 210 3.3E-32 T 12-10-2018 NPD12_3545 9a5b6dd7e6ec6958768ac90132d45f37 296 Gene3D G3DSA:3.30.70.3040 48 158 1.8E-11 T 12-10-2018 NPD12_3545 9a5b6dd7e6ec6958768ac90132d45f37 296 PIRSF PIRSF003097 1 296 2.5E-85 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 NPD12_3545 9a5b6dd7e6ec6958768ac90132d45f37 296 Pfam PF02687 FtsX-like permease family 201 294 1.5E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 Gene3D G3DSA:3.40.50.300 260 444 2.6E-63 T 12-10-2018 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 SMART SM00382 292 436 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 Pfam PF02954 Bacterial regulatory protein, Fis family 539 580 2.4E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 Gene3D G3DSA:1.10.8.60 445 526 2.6E-20 T 12-10-2018 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 Gene3D G3DSA:3.30.450.40 10 142 3.5E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 Pfam PF00158 Sigma-54 interaction domain 272 439 4.6E-68 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 359 374 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 SUPERFAMILY SSF46689 486 580 2.75E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 296 309 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 8 118 6.9E-8 T 12-10-2018 IPR039472 Sporulation stage V protein T, GAF domain NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 Gene3D G3DSA:1.10.10.60 533 580 2.5E-13 T 12-10-2018 NPD12_2941 af40a44eaa576e96d0d60d3b0a488f47 587 SUPERFAMILY SSF52540 271 516 6.07E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1536 712f36e221c7de6896ffc74e71cb5021 157 Pfam PF01799 [2Fe-2S] binding domain 77 149 6.6E-27 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 NPD12_1536 712f36e221c7de6896ffc74e71cb5021 157 Gene3D G3DSA:1.10.150.120 81 157 7.1E-29 T 12-10-2018 NPD12_1536 712f36e221c7de6896ffc74e71cb5021 157 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 56 1.6E-6 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 NPD12_1536 712f36e221c7de6896ffc74e71cb5021 157 SUPERFAMILY SSF47741 88 153 1.06E-26 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily NPD12_1536 712f36e221c7de6896ffc74e71cb5021 157 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 NPD12_1536 712f36e221c7de6896ffc74e71cb5021 157 Gene3D G3DSA:3.10.20.30 3 80 5.5E-29 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_1536 712f36e221c7de6896ffc74e71cb5021 157 SUPERFAMILY SSF54292 5 82 2.23E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 83 91 3.3E-11 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 92 101 3.3E-11 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 7 21 3.3E-11 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 5 129 8.3E-44 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 4 130 23.567 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 Gene3D G3DSA:1.10.1200.120 4 132 4.6E-41 T 12-10-2018 IPR036019 Gated mechanosensitive channel NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 SUPERFAMILY SSF81330 14 125 1.57E-34 T 12-10-2018 IPR036019 Gated mechanosensitive channel NPD12_726 085307e6c538b5b1f6172ba5b773b5ca 133 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 130 2.2E-46 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 NPD12_3027 8f90ae347677881cfb735b20900bb807 139 Pfam PF05105 Bacteriophage holin family 17 129 1.2E-39 T 12-10-2018 IPR006480 Bacteriophage holin family NPD12_3027 8f90ae347677881cfb735b20900bb807 139 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 12 134 2.3E-35 T 12-10-2018 IPR006480 Bacteriophage holin family NPD12_121 ceea536e70389233538f8a2765b8028f 625 Gene3D G3DSA:1.10.10.1800 459 549 2.9E-19 T 12-10-2018 NPD12_121 ceea536e70389233538f8a2765b8028f 625 Gene3D G3DSA:3.50.50.60 1 230 1.3E-78 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_121 ceea536e70389233538f8a2765b8028f 625 Gene3D G3DSA:3.50.50.60 303 458 2.2E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_121 ceea536e70389233538f8a2765b8028f 625 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.003 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 NPD12_121 ceea536e70389233538f8a2765b8028f 625 Gene3D G3DSA:1.10.150.570 569 620 1.9E-22 T 12-10-2018 NPD12_121 ceea536e70389233538f8a2765b8028f 625 SUPERFAMILY SSF51905 7 261 2.87E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_121 ceea536e70389233538f8a2765b8028f 625 Pfam PF13932 GidA associated domain 401 615 1.8E-77 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 NPD12_121 ceea536e70389233538f8a2765b8028f 625 Pfam PF01134 Glucose inhibited division protein A 9 398 4.3E-163 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 NPD12_121 ceea536e70389233538f8a2765b8028f 625 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 NPD12_121 ceea536e70389233538f8a2765b8028f 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 8.8E-6 T 12-10-2018 NPD12_121 ceea536e70389233538f8a2765b8028f 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 8.8E-6 T 12-10-2018 NPD12_121 ceea536e70389233538f8a2765b8028f 625 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 NPD12_121 ceea536e70389233538f8a2765b8028f 625 SMART SM01228 545 616 1.8E-40 T 12-10-2018 NPD12_121 ceea536e70389233538f8a2765b8028f 625 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 621 1.4E-267 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 NPD12_1997 b02c927acaefcbc537fe7bf4179b2998 189 Pfam PF01061 ABC-2 type transporter 3 152 8.3E-19 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 SMART SM00936 276 361 1.2E-7 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 SUPERFAMILY SSF56601 7 276 8.16E-65 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 295 359 3.3E-6 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 Gene3D G3DSA:3.40.710.10 20 297 3.1E-90 T 12-10-2018 NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 258 2.6E-62 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 3.3E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 3.3E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_2006 8fb0402a1a028e520f350b127a2abb09 378 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 68 79 3.3E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_1938 7155d642698210f7b20ec07c0acb6ce5 153 SUPERFAMILY SSF103039 1 150 6.54E-27 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_1938 7155d642698210f7b20ec07c0acb6ce5 153 Gene3D G3DSA:3.40.1550.10 1 152 2.0E-37 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_1938 7155d642698210f7b20ec07c0acb6ce5 153 Pfam PF13690 Chemotaxis phosphatase CheX 45 130 2.4E-12 T 12-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 Pfam PF00448 SRP54-type protein, GTPase domain 103 303 3.5E-78 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 SMART SM00382 102 260 2.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 SUPERFAMILY SSF52540 102 302 9.88E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 SUPERFAMILY SSF47364 5 83 7.07E-22 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 SMART SM00963 9 90 4.4E-20 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 277 290 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 SMART SM00962 103 303 1.1E-107 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 Gene3D G3DSA:3.40.50.300 103 292 7.5E-112 T 12-10-2018 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 33 303 59.098 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 Gene3D G3DSA:1.20.120.140 6 302 7.5E-112 T 12-10-2018 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 34 303 3.5E-109 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 NPD12_2499 8924fd50028ac84a6790aa9c13dd3619 303 Pfam PF02881 SRP54-type protein, helical bundle domain 20 83 6.8E-13 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 NPD12_298 23e24c2de7391d2fa40c49089f7fc7c5 145 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.2E-61 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 NPD12_298 23e24c2de7391d2fa40c49089f7fc7c5 145 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 4.4E-61 T 12-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 NPD12_298 23e24c2de7391d2fa40c49089f7fc7c5 145 Gene3D G3DSA:3.40.1400.10 1 145 3.4E-63 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 NPD12_298 23e24c2de7391d2fa40c49089f7fc7c5 145 SUPERFAMILY SSF89623 1 144 1.31E-62 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 NPD12_298 23e24c2de7391d2fa40c49089f7fc7c5 145 PIRSF PIRSF005384 1 145 6.0E-62 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 NPD12_298 23e24c2de7391d2fa40c49089f7fc7c5 145 Pfam PF02502 Ribose/Galactose Isomerase 3 140 3.4E-62 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Gene3D G3DSA:3.50.50.60 576 778 5.6E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Gene3D G3DSA:3.50.50.60 446 574 8.0E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Gene3D G3DSA:1.10.1060.10 343 445 3.0E-27 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 448 739 1.1E-28 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 355 431 1.2E-20 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 SUPERFAMILY SSF54862 254 312 5.42E-7 T 12-10-2018 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 SUPERFAMILY SSF51971 447 690 1.82E-57 T 12-10-2018 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 PRINTS PR00419 Adrenodoxin reductase family signature 581 595 7.1E-21 T 12-10-2018 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 PRINTS PR00419 Adrenodoxin reductase family signature 472 485 7.1E-21 T 12-10-2018 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 PRINTS PR00419 Adrenodoxin reductase family signature 514 524 7.1E-21 T 12-10-2018 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 PRINTS PR00419 Adrenodoxin reductase family signature 449 471 7.1E-21 T 12-10-2018 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 SUPERFAMILY SSF46548 780 853 5.02E-10 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Gene3D G3DSA:3.30.70.20 254 342 8.2E-6 T 12-10-2018 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Pfam PF00037 4Fe-4S binding domain 830 852 1.4E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_602 da47d8916f90675cb81f4bfa65508691 892 Pfam PF00037 4Fe-4S binding domain 286 307 5.5E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_602 da47d8916f90675cb81f4bfa65508691 892 SUPERFAMILY SSF46548 328 457 3.4E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_602 da47d8916f90675cb81f4bfa65508691 892 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 292 303 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2219 c84f2bc2c34f10c134c50d55e4eacd6e 374 SUPERFAMILY SSF102114 90 269 2.49E-16 T 12-10-2018 NPD12_2219 c84f2bc2c34f10c134c50d55e4eacd6e 374 Gene3D G3DSA:3.20.20.70 88 318 1.1E-14 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3349 f37c04dac121fd3b5eb79d9efd255dc6 283 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 1 282 37.635 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_3349 f37c04dac121fd3b5eb79d9efd255dc6 283 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 259 4.0E-71 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 NPD12_3349 f37c04dac121fd3b5eb79d9efd255dc6 283 SMART SM00934 15 264 1.7E-43 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_3349 f37c04dac121fd3b5eb79d9efd255dc6 283 SUPERFAMILY SSF51366 3 260 3.2E-69 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 NPD12_3349 f37c04dac121fd3b5eb79d9efd255dc6 283 Gene3D G3DSA:3.20.20.70 1 282 1.4E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3349 f37c04dac121fd3b5eb79d9efd255dc6 283 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 256 3.8E-27 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 NPD12_243 73a81ad7bb151fbe360f43139e168644 402 Pfam PF12704 MacB-like periplasmic core domain 21 237 1.1E-32 T 12-10-2018 IPR025857 MacB-like periplasmic core domain NPD12_243 73a81ad7bb151fbe360f43139e168644 402 Pfam PF02687 FtsX-like permease family 308 395 1.8E-14 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_2542 cc32bb95aef6349ad79b6bb2ca132b78 185 Pfam PF03602 Conserved hypothetical protein 95 1 181 9.8E-61 T 12-10-2018 NPD12_2542 cc32bb95aef6349ad79b6bb2ca132b78 185 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 5.3E-48 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 NPD12_2542 cc32bb95aef6349ad79b6bb2ca132b78 185 SUPERFAMILY SSF53335 1 181 2.77E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2542 cc32bb95aef6349ad79b6bb2ca132b78 185 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 NPD12_2542 cc32bb95aef6349ad79b6bb2ca132b78 185 PIRSF PIRSF004553 1 184 1.6E-58 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 NPD12_2542 cc32bb95aef6349ad79b6bb2ca132b78 185 Gene3D G3DSA:3.40.50.150 1 185 1.5E-59 T 12-10-2018 NPD12_2563 a06a93b9ef583ebb7732f6e7400df143 292 Pfam PF03755 YicC-like family, N-terminal region 2 156 4.4E-45 T 12-10-2018 IPR013527 YicC-like, N-terminal NPD12_2563 a06a93b9ef583ebb7732f6e7400df143 292 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 292 3.0E-80 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 NPD12_2563 a06a93b9ef583ebb7732f6e7400df143 292 Pfam PF08340 Domain of unknown function (DUF1732) 209 292 7.3E-36 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 1.0E-21 T 12-10-2018 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.662 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 Gene3D G3DSA:1.10.720.90 2 55 1.6E-21 T 12-10-2018 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 Pfam PF00453 Ribosomal protein L20 3 109 3.3E-47 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.7E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.7E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.7E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.6E-48 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 SUPERFAMILY SSF74731 3 117 9.42E-48 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3243 180ee0ccc436da8499d096424659a1ea 119 Gene3D G3DSA:1.10.1900.20 56 119 1.2E-29 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_2669 e9527e17f08760adff474a54dfbe3b5f 287 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 251 4.3E-31 T 12-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain NPD12_2669 e9527e17f08760adff474a54dfbe3b5f 287 SUPERFAMILY SSF53590 1 254 1.44E-40 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like NPD12_2669 e9527e17f08760adff474a54dfbe3b5f 287 Gene3D G3DSA:3.90.245.10 1 78 2.6E-11 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like NPD12_2669 e9527e17f08760adff474a54dfbe3b5f 287 Gene3D G3DSA:3.90.245.10 79 284 2.4E-30 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like NPD12_3226 f300fe460f8762d808851642ba0406e7 486 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 375 468 3.5E-10 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 NPD12_3226 f300fe460f8762d808851642ba0406e7 486 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 9 373 1.3E-94 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 NPD12_3226 f300fe460f8762d808851642ba0406e7 486 SUPERFAMILY SSF55904 345 485 2.09E-35 T 12-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 NPD12_3226 f300fe460f8762d808851642ba0406e7 486 Gene3D G3DSA:3.90.105.10 423 479 6.9E-20 T 12-10-2018 NPD12_3226 f300fe460f8762d808851642ba0406e7 486 Gene3D G3DSA:3.40.640.10 9 286 4.3E-103 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_3226 f300fe460f8762d808851642ba0406e7 486 SUPERFAMILY SSF53383 9 387 7.1E-98 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1882 507efa4244479349d4efbbb693d76c62 388 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_1882 507efa4244479349d4efbbb693d76c62 388 Gene3D G3DSA:1.20.1090.10 183 384 6.0E-64 T 12-10-2018 NPD12_1882 507efa4244479349d4efbbb693d76c62 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 373 7.8E-118 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 NPD12_1882 507efa4244479349d4efbbb693d76c62 388 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 256 276 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_1882 507efa4244479349d4efbbb693d76c62 388 SUPERFAMILY SSF56796 3 384 7.72E-123 T 12-10-2018 NPD12_1882 507efa4244479349d4efbbb693d76c62 388 Gene3D G3DSA:3.40.50.1970 1 182 9.3E-53 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 Gene3D G3DSA:3.80.10.10 47 361 1.7E-64 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 Pfam PF12799 Leucine Rich repeats (2 copies) 257 299 3.0E-8 T 12-10-2018 IPR025875 Leucine rich repeat 4 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 234 252 170.0 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 102 123 33.0 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 146 170 440.0 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 124 145 230.0 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 190 211 150.0 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 80 101 780.0 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 300 321 25.0 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SMART SM00365 256 280 3.1 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 Pfam PF13855 Leucine rich repeat 104 158 1.0E-6 T 12-10-2018 IPR001611 Leucine-rich repeat GO:0005515 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 SUPERFAMILY SSF52058 77 330 1.59E-51 T 12-10-2018 NPD12_3213 79c2d881d1cbb5b15a43b9857fc69e37 364 Pfam PF13516 Leucine Rich repeat 213 227 1.6 T 12-10-2018 IPR001611 Leucine-rich repeat GO:0005515 NPD12_3450 d9375b8667f768dbd0624adf94c260bb 237 Pfam PF00814 Glycoprotease family 32 224 2.6E-26 T 12-10-2018 IPR000905 Gcp-like domain NPD12_3450 d9375b8667f768dbd0624adf94c260bb 237 SUPERFAMILY SSF53067 1 102 1.73E-24 T 12-10-2018 NPD12_3450 d9375b8667f768dbd0624adf94c260bb 237 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 219 2.1E-51 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 NPD12_3450 d9375b8667f768dbd0624adf94c260bb 237 Gene3D G3DSA:3.30.420.40 95 188 2.1E-54 T 12-10-2018 NPD12_3450 d9375b8667f768dbd0624adf94c260bb 237 SUPERFAMILY SSF53067 108 217 1.81E-13 T 12-10-2018 NPD12_3450 d9375b8667f768dbd0624adf94c260bb 237 Gene3D G3DSA:3.30.420.40 3 221 2.1E-54 T 12-10-2018 NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 27 469 2.1E-167 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 PIRSF PIRSF000485 23 482 1.6E-180 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 26 468 47.923 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 Gene3D G3DSA:3.40.50.2020 288 452 9.4E-167 T 12-10-2018 NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 Pfam PF00156 Phosphoribosyl transferase domain 293 401 1.9E-11 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 Gene3D G3DSA:3.60.20.10 27 470 9.4E-167 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 Pfam PF13537 Glutamine amidotransferase domain 107 226 1.2E-20 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 SUPERFAMILY SSF56235 27 254 5.06E-69 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_2930 50264cffffeb3e94fac06b8300e02d58 482 SUPERFAMILY SSF53271 264 473 4.98E-73 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_1976 938677ab727069ebde83e211d4dcf023 164 SMART SM00450 54 162 3.7E-5 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1976 938677ab727069ebde83e211d4dcf023 164 Gene3D G3DSA:3.40.250.10 30 162 4.7E-16 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1976 938677ab727069ebde83e211d4dcf023 164 Pfam PF00581 Rhodanese-like domain 55 157 8.2E-11 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1976 938677ab727069ebde83e211d4dcf023 164 SUPERFAMILY SSF52821 46 158 1.7E-13 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_846 75510173cf011651b356d6fed514ac5b 323 SUPERFAMILY SSF53822 40 289 8.73E-12 T 12-10-2018 IPR028082 Periplasmic binding protein-like I NPD12_846 75510173cf011651b356d6fed514ac5b 323 Gene3D G3DSA:3.40.50.2300 42 292 4.9E-87 T 12-10-2018 NPD12_846 75510173cf011651b356d6fed514ac5b 323 Pfam PF04392 ABC transporter substrate binding protein 32 308 3.1E-83 T 12-10-2018 IPR007487 ABC transporter, substrate-binding protein NPD12_846 75510173cf011651b356d6fed514ac5b 323 Gene3D G3DSA:3.40.50.2300 145 308 4.9E-87 T 12-10-2018 NPD12_2997 cf2f6a5cc396d771a832ac6c0ac50af0 166 SUPERFAMILY SSF55486 1 165 1.29E-42 T 12-10-2018 NPD12_2997 cf2f6a5cc396d771a832ac6c0ac50af0 166 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 166 22.895 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 NPD12_2997 cf2f6a5cc396d771a832ac6c0ac50af0 166 Gene3D G3DSA:3.40.390.30 1 166 3.8E-42 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 NPD12_2997 cf2f6a5cc396d771a832ac6c0ac50af0 166 Pfam PF02130 Uncharacterized protein family UPF0054 12 162 1.6E-46 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 NPD12_2997 cf2f6a5cc396d771a832ac6c0ac50af0 166 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 162 4.1E-38 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 NPD12_2997 cf2f6a5cc396d771a832ac6c0ac50af0 166 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 132 142 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 Gene3D G3DSA:3.40.50.200 90 397 1.0E-54 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 161 3.9E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 340 356 3.9E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 108 127 3.9E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 SUPERFAMILY SSF52743 51 397 1.57E-53 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 Pfam PF00082 Subtilase family 108 362 6.3E-21 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 152 162 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site NPD12_60 1d82f29849b6128ec4aaf8c34166ea96 398 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 113 123 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 SUPERFAMILY SSF50249 2 124 3.0E-52 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 PIRSF PIRSF002133 1 124 1.0E-53 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 2.2E-68 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 Gene3D G3DSA:2.40.50.140 1 125 7.3E-63 T 12-10-2018 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 40.132 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 4.9E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 4.9E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 4.9E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 4.9E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 4.9E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 4.9E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3644 9d7bdd35aae46b5a1046bec9f30f1289 125 Pfam PF00164 Ribosomal protein S12/S23 12 123 7.3E-42 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 Gene3D G3DSA:3.90.400.10 108 167 2.2E-23 T 12-10-2018 NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 473 546 8.1E-8 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 SUPERFAMILY SSF51445 4 469 1.49E-147 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 SMART SM00642 11 412 6.7E-144 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 Gene3D G3DSA:3.20.20.80 2 107 4.4E-45 T 12-10-2018 NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 4 551 4.1E-271 T 12-10-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 Gene3D G3DSA:3.20.20.80 168 473 2.2E-117 T 12-10-2018 NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 Gene3D G3DSA:2.60.40.1180 474 555 5.3E-25 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 SUPERFAMILY SSF51011 473 552 3.82E-19 T 12-10-2018 NPD12_2150 fe4973ed7dcaf67e5e9584a6a46de978 555 Pfam PF00128 Alpha amylase, catalytic domain 26 369 6.6E-119 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 NPD12_299 04cf3353c65d064a17632ee594f500e8 209 Gene3D G3DSA:3.40.50.2020 2 209 1.0E-80 T 12-10-2018 NPD12_299 04cf3353c65d064a17632ee594f500e8 209 Pfam PF14681 Uracil phosphoribosyltransferase 8 208 9.9E-75 T 12-10-2018 NPD12_299 04cf3353c65d064a17632ee594f500e8 209 SUPERFAMILY SSF53271 5 207 6.56E-71 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_299 04cf3353c65d064a17632ee594f500e8 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 3.8E-90 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 NPD12_299 04cf3353c65d064a17632ee594f500e8 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.426 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 NPD12_1499 6338ae9ebbb54a29048b8175d252db2f 137 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 5 135 1.3E-36 T 12-10-2018 IPR014986 Clostridium phage phiCD119, XkdN NPD12_1499 6338ae9ebbb54a29048b8175d252db2f 137 Gene3D G3DSA:3.30.2220.30 10 125 2.0E-30 T 12-10-2018 IPR038559 Clostridium phage phiCD119, XkdN superfamily NPD12_3801 9c46cfd2f5815e31e712a66177da9809 303 SUPERFAMILY SSF53067 4 135 1.49E-12 T 12-10-2018 NPD12_3801 9c46cfd2f5815e31e712a66177da9809 303 Gene3D G3DSA:3.30.420.40 147 274 2.1E-24 T 12-10-2018 NPD12_3801 9c46cfd2f5815e31e712a66177da9809 303 SUPERFAMILY SSF53067 145 283 4.61E-12 T 12-10-2018 NPD12_3801 9c46cfd2f5815e31e712a66177da9809 303 Gene3D G3DSA:3.30.420.40 4 283 2.1E-24 T 12-10-2018 NPD12_1146 a1efd2a479f360c856bb9acb41ee46a7 340 Gene3D G3DSA:3.40.980.10 146 307 2.3E-29 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_1146 a1efd2a479f360c856bb9acb41ee46a7 340 SUPERFAMILY SSF53218 169 309 8.51E-34 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily NPD12_1146 a1efd2a479f360c856bb9acb41ee46a7 340 SMART SM00852 173 305 4.3E-22 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_1146 a1efd2a479f360c856bb9acb41ee46a7 340 Gene3D G3DSA:3.90.105.10 1 55 5.1E-7 T 12-10-2018 NPD12_1146 a1efd2a479f360c856bb9acb41ee46a7 340 Pfam PF00994 Probable molybdopterin binding domain 174 302 4.5E-19 T 12-10-2018 IPR001453 MoaB/Mog domain NPD12_1936 36f15c039241aa705f6309bad4b8dba5 171 Pfam PF00210 Ferritin-like domain 7 143 3.0E-42 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 NPD12_1936 36f15c039241aa705f6309bad4b8dba5 171 SUPERFAMILY SSF47240 1 159 9.42E-60 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_1936 36f15c039241aa705f6309bad4b8dba5 171 Gene3D G3DSA:1.20.1260.10 1 171 1.0E-54 T 12-10-2018 IPR012347 Ferritin-like NPD12_344 cac7655eb1bc77e86776919f8415cbc4 134 SUPERFAMILY SSF52821 14 123 3.01E-27 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_344 cac7655eb1bc77e86776919f8415cbc4 134 Pfam PF00581 Rhodanese-like domain 38 123 1.1E-16 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_344 cac7655eb1bc77e86776919f8415cbc4 134 Gene3D G3DSA:3.40.250.10 27 132 3.0E-25 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_344 cac7655eb1bc77e86776919f8415cbc4 134 SMART SM00450 37 134 6.7E-12 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_3629 fdad47752323bcec81e3034daaff7e15 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_3629 fdad47752323bcec81e3034daaff7e15 122 Gene3D G3DSA:2.40.150.20 1 122 2.0E-53 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3629 fdad47752323bcec81e3034daaff7e15 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.7E-57 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 NPD12_3629 fdad47752323bcec81e3034daaff7e15 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 2.2E-54 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 NPD12_3629 fdad47752323bcec81e3034daaff7e15 122 SMART SM01374 1 122 4.6E-86 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 NPD12_3629 fdad47752323bcec81e3034daaff7e15 122 SUPERFAMILY SSF50193 1 122 2.49E-51 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3629 fdad47752323bcec81e3034daaff7e15 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.67 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 Gene3D G3DSA:3.40.50.720 5 247 3.4E-84 T 12-10-2018 NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 SUPERFAMILY SSF51735 6 246 5.88E-85 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_669 cb1ac424cb05999cb72885c9479c51e4 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 7.6E-66 T 12-10-2018 NPD12_3300 71559ddf05bdc71244511d2be170bade 442 Gene3D G3DSA:3.40.50.300 51 267 4.1E-50 T 12-10-2018 NPD12_3300 71559ddf05bdc71244511d2be170bade 442 SUPERFAMILY SSF52540 46 338 3.93E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3300 71559ddf05bdc71244511d2be170bade 442 Pfam PF07728 AAA domain (dynein-related subfamily) 87 214 4.2E-19 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 NPD12_3300 71559ddf05bdc71244511d2be170bade 442 SMART SM00382 84 222 0.0016 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 Hamap MF_00163 Peptide deformylase [def]. 24 177 26.826 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 26 173 2.3E-42 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 PIRSF PIRSF004749 3 176 1.7E-46 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 Pfam PF01327 Polypeptide deformylase 26 171 5.5E-45 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 Gene3D G3DSA:3.90.45.10 12 178 3.2E-50 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 SUPERFAMILY SSF56420 16 172 7.46E-48 T 12-10-2018 IPR036821 Peptide deformylase superfamily NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 PRINTS PR01576 Peptide deformylase signature 110 121 2.7E-30 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 PRINTS PR01576 Peptide deformylase signature 122 140 2.7E-30 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 PRINTS PR01576 Peptide deformylase signature 55 84 2.7E-30 T 12-10-2018 IPR023635 Peptide deformylase NPD12_2670 e84aa725e0ca2b2b4f82fa72c2d7500f 178 PRINTS PR01576 Peptide deformylase signature 141 170 2.7E-30 T 12-10-2018 IPR023635 Peptide deformylase NPD12_837 81cac6577c00f4733431093e68d4e739 232 Gene3D G3DSA:1.10.3910.10 1 65 5.5E-7 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily NPD12_837 81cac6577c00f4733431093e68d4e739 232 Gene3D G3DSA:1.20.120.520 71 232 3.9E-17 T 12-10-2018 NPD12_837 81cac6577c00f4733431093e68d4e739 232 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 11 231 4.8E-75 T 12-10-2018 IPR019903 Repair of iron centres family NPD12_837 81cac6577c00f4733431093e68d4e739 232 Pfam PF01814 Hemerythrin HHE cation binding domain 86 232 6.6E-20 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 NPD12_837 81cac6577c00f4733431093e68d4e739 232 SUPERFAMILY SSF140683 1 65 1.31E-6 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily NPD12_837 81cac6577c00f4733431093e68d4e739 232 Pfam PF04405 Domain of Unknown function (DUF542) 8 60 3.9E-19 T 12-10-2018 IPR019903 Repair of iron centres family NPD12_2259 d77fa1ee4f581ff605153ae08d0d92cf 380 Gene3D G3DSA:1.20.1090.10 168 379 4.5E-61 T 12-10-2018 NPD12_2259 d77fa1ee4f581ff605153ae08d0d92cf 380 Gene3D G3DSA:3.40.50.1970 1 167 3.1E-45 T 12-10-2018 NPD12_2259 d77fa1ee4f581ff605153ae08d0d92cf 380 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 156 184 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_2259 d77fa1ee4f581ff605153ae08d0d92cf 380 SUPERFAMILY SSF56796 3 377 6.8E-107 T 12-10-2018 NPD12_2259 d77fa1ee4f581ff605153ae08d0d92cf 380 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 371 9.9E-109 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 SMART SM00382 313 475 1.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 SMART SM00382 28 171 2.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 Gene3D G3DSA:3.40.50.300 251 511 5.8E-55 T 12-10-2018 NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 SUPERFAMILY SSF52540 4 176 1.83E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 Gene3D G3DSA:3.40.50.300 85 224 5.1E-28 T 12-10-2018 NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 Pfam PF00005 ABC transporter 23 126 5.4E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 Gene3D G3DSA:3.40.50.300 1 84 3.1E-17 T 12-10-2018 NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 SUPERFAMILY SSF52540 278 488 1.78E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_725 31a28b5d1e5082cd36ae316510746c21 552 Pfam PF00005 ABC transporter 305 430 8.0E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1814 49a127b862d2cb49c4f0c71a8cfb5c3c 110 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 4 90 20.825 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 NPD12_1814 49a127b862d2cb49c4f0c71a8cfb5c3c 110 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 13 93 6.8E-16 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 NPD12_1814 49a127b862d2cb49c4f0c71a8cfb5c3c 110 SUPERFAMILY SSF101386 5 94 1.87E-25 T 12-10-2018 NPD12_1814 49a127b862d2cb49c4f0c71a8cfb5c3c 110 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 8 90 4.9E-31 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 NPD12_1814 49a127b862d2cb49c4f0c71a8cfb5c3c 110 Gene3D G3DSA:1.10.287.1080 3 97 5.2E-32 T 12-10-2018 NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 SUPERFAMILY SSF47384 75 144 9.42E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 Gene3D G3DSA:3.30.565.10 148 302 1.0E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 Pfam PF00512 His Kinase A (phospho-acceptor) domain 81 142 1.2E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 191 299 9.2E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 SUPERFAMILY SSF55874 134 298 4.85E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 SMART SM00387 190 302 3.8E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 Gene3D G3DSA:1.10.287.130 71 144 1.5E-16 T 12-10-2018 NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 SMART SM00388 78 144 1.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 PRINTS PR00344 Bacterial sensor protein C-terminal signature 227 241 6.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 PRINTS PR00344 Bacterial sensor protein C-terminal signature 262 280 6.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2407 1ac7b61306d00e5bc225ec4074d10641 303 PRINTS PR00344 Bacterial sensor protein C-terminal signature 245 255 6.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1848 a65311c92f8e7061a54f5105d5e518ef 207 Pfam PF02659 Putative manganese efflux pump 50 203 3.8E-12 T 12-10-2018 IPR003810 Putative manganese efflux pump NPD12_1848 a65311c92f8e7061a54f5105d5e518ef 207 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 3 206 1.1E-68 T 12-10-2018 IPR014205 Sporulation protein YtaF NPD12_1900 b0649c150f4938cdff141c418d95f7e1 490 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 161 318 4.9E-28 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1900 b0649c150f4938cdff141c418d95f7e1 490 SUPERFAMILY SSF58104 91 347 1.57E-46 T 12-10-2018 NPD12_1900 b0649c150f4938cdff141c418d95f7e1 490 Gene3D G3DSA:1.20.120.30 362 481 1.1E-6 T 12-10-2018 NPD12_1900 b0649c150f4938cdff141c418d95f7e1 490 Pfam PF13682 Chemoreceptor zinc-binding domain 379 439 1.9E-7 T 12-10-2018 IPR025991 Chemoreceptor zinc-binding domain NPD12_1900 b0649c150f4938cdff141c418d95f7e1 490 Gene3D G3DSA:1.10.287.950 56 356 9.4E-49 T 12-10-2018 NPD12_1900 b0649c150f4938cdff141c418d95f7e1 490 SMART SM00283 85 332 3.4E-24 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_3060 bb43c698487f7049b30c97aa5289ecca 91 Pfam PF08774 VRR-NUC domain 12 78 1.9E-7 T 12-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 NPD12_3060 bb43c698487f7049b30c97aa5289ecca 91 SMART SM00990 1 81 1.2E-25 T 12-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 NPD12_3060 bb43c698487f7049b30c97aa5289ecca 91 Gene3D G3DSA:3.40.1350.10 2 90 1.1E-29 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 NPD12_1682 19e479fb09b36d251382f0635326b24f 392 Pfam PF01546 Peptidase family M20/M25/M40 73 385 3.1E-34 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_1682 19e479fb09b36d251382f0635326b24f 392 Gene3D G3DSA:3.30.70.360 183 297 2.0E-132 T 12-10-2018 NPD12_1682 19e479fb09b36d251382f0635326b24f 392 Pfam PF07687 Peptidase dimerisation domain 188 284 8.1E-14 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_1682 19e479fb09b36d251382f0635326b24f 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 378 3.1E-108 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 NPD12_1682 19e479fb09b36d251382f0635326b24f 392 SUPERFAMILY SSF55031 188 292 3.14E-30 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain NPD12_1682 19e479fb09b36d251382f0635326b24f 392 SUPERFAMILY SSF53187 8 391 5.97E-78 T 12-10-2018 NPD12_1682 19e479fb09b36d251382f0635326b24f 392 PIRSF PIRSF005962 2 392 2.0E-122 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 NPD12_1682 19e479fb09b36d251382f0635326b24f 392 Gene3D G3DSA:3.40.630.10 17 375 2.0E-132 T 12-10-2018 NPD12_2795 593e33d573caf9d131b87704aae2a047 54 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 3 28 6.8E-5 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 NPD12_1012 8a631e2c91b628f40ac0b2bf1b834ec0 451 Pfam PF07833 Copper amine oxidase N-terminal domain 81 166 7.0E-6 T 12-10-2018 IPR012854 Copper amine oxidase-like, N-terminal NPD12_1012 8a631e2c91b628f40ac0b2bf1b834ec0 451 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 190 437 5.1E-57 T 12-10-2018 IPR018763 Protein of unknown function DUF2334 NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 Pfam PF05239 PRC-barrel domain 92 159 3.3E-9 T 12-10-2018 IPR027275 PRC-barrel domain NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 SUPERFAMILY SSF50346 93 159 9.03E-18 T 12-10-2018 IPR011033 PRC-barrel-like superfamily NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 SUPERFAMILY SSF50447 3 83 3.18E-18 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 Gene3D G3DSA:2.40.30.60 4 85 1.6E-19 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 161 22.72 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 Pfam PF01782 RimM N-terminal domain 7 83 6.4E-21 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 159 2.5E-45 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 NPD12_2494 f5ed008805062060cb3ba78d70400de0 164 Gene3D G3DSA:2.30.30.240 88 162 9.2E-19 T 12-10-2018 NPD12_2263 1f3ba66a5d33f70deef769d2ac4f4de4 299 Pfam PF13673 Acetyltransferase (GNAT) domain 168 282 2.2E-8 T 12-10-2018 IPR000182 GNAT domain NPD12_2263 1f3ba66a5d33f70deef769d2ac4f4de4 299 SUPERFAMILY SSF46785 21 116 3.94E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2263 1f3ba66a5d33f70deef769d2ac4f4de4 299 Gene3D G3DSA:3.40.630.30 153 287 9.8E-14 T 12-10-2018 NPD12_2263 1f3ba66a5d33f70deef769d2ac4f4de4 299 SMART SM00347 23 125 1.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2263 1f3ba66a5d33f70deef769d2ac4f4de4 299 SUPERFAMILY SSF55729 154 286 1.95E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2263 1f3ba66a5d33f70deef769d2ac4f4de4 299 Gene3D G3DSA:1.10.10.10 2 133 5.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2263 1f3ba66a5d33f70deef769d2ac4f4de4 299 Pfam PF12802 MarR family 28 86 3.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1776 18e68916da54ec6f1016cb1abe668794 276 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 8 274 8.5E-134 T 12-10-2018 IPR009215 TIM-barrel domain, IGPS-like NPD12_1776 18e68916da54ec6f1016cb1abe668794 276 SUPERFAMILY SSF51621 3 197 1.16E-85 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 NPD12_1776 18e68916da54ec6f1016cb1abe668794 276 Gene3D G3DSA:3.20.20.70 1 252 1.3E-121 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1776 18e68916da54ec6f1016cb1abe668794 276 Gene3D G3DSA:1.20.5.460 253 276 5.3E-6 T 12-10-2018 NPD12_1776 18e68916da54ec6f1016cb1abe668794 276 PIRSF PIRSF034452 1 276 3.3E-149 T 12-10-2018 IPR009215 TIM-barrel domain, IGPS-like NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 Pfam PF03448 MgtE intracellular N domain 23 125 2.3E-28 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 Pfam PF01769 Divalent cation transporter 313 435 4.1E-32 T 12-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 SMART SM00924 23 127 1.6E-32 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 Gene3D G3DSA:1.25.60.10 1 122 1.3E-25 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 SUPERFAMILY SSF161093 270 442 7.32E-53 T 12-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 Gene3D G3DSA:3.10.580.10 123 251 1.2E-42 T 12-10-2018 NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 SUPERFAMILY SSF158791 2 124 2.09E-27 T 12-10-2018 NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 SMART SM00116 134 187 53.0 T 12-10-2018 IPR000644 CBS domain NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 SMART SM00116 198 246 3.3E-5 T 12-10-2018 IPR000644 CBS domain NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 SUPERFAMILY SSF54631 127 266 4.3E-31 T 12-10-2018 NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 Pfam PF00571 CBS domain 191 245 3.6E-8 T 12-10-2018 IPR000644 CBS domain NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 Pfam PF00571 CBS domain 127 183 1.2E-5 T 12-10-2018 IPR000644 CBS domain NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 TIGRFAM TIGR00400 mgtE: magnesium transporter 3 444 1.1E-157 T 12-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 NPD12_1317 390e16a971d3e803b42a2e1ac5772ffb 444 Gene3D G3DSA:1.10.357.20 265 442 3.7E-62 T 12-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 Pfam PF02355 Protein export membrane protein 235 399 1.6E-16 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 PRINTS PR00702 Acriflavin resistance protein family signature 249 272 6.3E-9 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 PRINTS PR00702 Acriflavin resistance protein family signature 302 326 6.3E-9 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 PRINTS PR00702 Acriflavin resistance protein family signature 377 400 6.3E-9 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 163 393 1.6E-73 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 134 400 1.2E-102 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 Gene3D G3DSA:1.20.1640.10 225 405 3.2E-11 T 12-10-2018 NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 Gene3D G3DSA:3.30.1360.200 82 224 4.5E-31 T 12-10-2018 NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 7 413 37.242 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 NPD12_3172 eb006bf03d1ca9e17e1abd0db027b66e 422 SUPERFAMILY SSF82866 149 403 2.22E-42 T 12-10-2018 NPD12_127 47bcd1f1d295da6f8d28b3e5105facf9 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_127 47bcd1f1d295da6f8d28b3e5105facf9 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 31 9.0E-10 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_127 47bcd1f1d295da6f8d28b3e5105facf9 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 4 44 4.1E-18 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_127 47bcd1f1d295da6f8d28b3e5105facf9 44 Pfam PF00468 Ribosomal protein L34 2 44 7.0E-21 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_127 47bcd1f1d295da6f8d28b3e5105facf9 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 14.406 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 Gene3D G3DSA:3.40.50.720 1 261 2.1E-76 T 12-10-2018 NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 257 1.7E-56 T 12-10-2018 NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 SUPERFAMILY SSF51735 4 259 2.88E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR NPD12_3571 e4f80fb388686f2ef94635df8168b86d 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 NPD12_1725 d9141662b6e8aeb435fc8bca3735b226 147 Pfam PF01252 Signal peptidase (SPase) II 6 144 3.3E-35 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_1725 d9141662b6e8aeb435fc8bca3735b226 147 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 1.8E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_1725 d9141662b6e8aeb435fc8bca3735b226 147 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 88 103 1.8E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_1725 d9141662b6e8aeb435fc8bca3735b226 147 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 44 52 1.8E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_1725 d9141662b6e8aeb435fc8bca3735b226 147 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 147 15.897 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_1725 d9141662b6e8aeb435fc8bca3735b226 147 ProSitePatterns PS00855 Signal peptidases II signature. 91 103 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_1725 d9141662b6e8aeb435fc8bca3735b226 147 TIGRFAM TIGR00077 lspA: signal peptidase II 4 145 3.8E-33 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 Gene3D G3DSA:2.40.240.10 3 90 3.6E-22 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 Gene3D G3DSA:2.170.120.20 94 177 2.2E-18 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 97 175 4.6E-19 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 SUPERFAMILY SSF50715 3 176 1.5E-42 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 13 90 1.0E-19 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 Pfam PF01386 Ribosomal L25p family 7 87 1.1E-19 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 2 177 21.639 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3225 2e3354d1433d0ca6e906dbb8ade4013e 178 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 13 175 7.4E-39 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 NPD12_3559 b143686870896e5283487d57f580e3e4 285 PIRSF PIRSF035875 2 285 3.9E-79 T 12-10-2018 IPR017039 Virulence factor BrkB NPD12_3559 b143686870896e5283487d57f580e3e4 285 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 14 271 3.5E-51 T 12-10-2018 IPR017039 Virulence factor BrkB NPD12_3559 b143686870896e5283487d57f580e3e4 285 Pfam PF03631 Virulence factor BrkB 22 271 2.0E-65 T 12-10-2018 IPR017039 Virulence factor BrkB NPD12_1326 86fdd67e9e72503a346fa5f91fe6fd23 186 SUPERFAMILY SSF52499 5 184 3.27E-29 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 NPD12_1326 86fdd67e9e72503a346fa5f91fe6fd23 186 Gene3D G3DSA:3.40.50.850 3 186 2.6E-40 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 NPD12_1326 86fdd67e9e72503a346fa5f91fe6fd23 186 Pfam PF00857 Isochorismatase family 5 186 8.7E-19 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 NPD12_3162 5458beb2caa8921418e5a41a47e31c92 142 PIRSF PIRSF004923 1 142 1.8E-19 T 12-10-2018 IPR026268 Protein RseC NPD12_3162 5458beb2caa8921418e5a41a47e31c92 142 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 138 8.3E-26 T 12-10-2018 NPD12_2216 3d3535841ecd8be8a0d8deb8df206434 421 Gene3D G3DSA:2.30.40.10 5 404 2.9E-177 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2216 3d3535841ecd8be8a0d8deb8df206434 421 Pfam PF07969 Amidohydrolase family 38 399 2.8E-48 T 12-10-2018 IPR013108 Amidohydrolase 3 NPD12_2216 3d3535841ecd8be8a0d8deb8df206434 421 SUPERFAMILY SSF51338 2 73 2.4E-13 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2216 3d3535841ecd8be8a0d8deb8df206434 421 Gene3D G3DSA:3.20.20.140 51 358 2.9E-177 T 12-10-2018 NPD12_2216 3d3535841ecd8be8a0d8deb8df206434 421 SUPERFAMILY SSF51556 50 370 5.96E-106 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_2889 401a25d99dbcc135957da6ccecc24358 104 PRINTS PR00131 Glycosyl hydrolase family 1 signature 80 92 3.6E-6 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_2889 401a25d99dbcc135957da6ccecc24358 104 PRINTS PR00131 Glycosyl hydrolase family 1 signature 14 22 3.6E-6 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_2889 401a25d99dbcc135957da6ccecc24358 104 PRINTS PR00131 Glycosyl hydrolase family 1 signature 35 46 3.6E-6 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_2889 401a25d99dbcc135957da6ccecc24358 104 PRINTS PR00131 Glycosyl hydrolase family 1 signature 56 73 3.6E-6 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_2889 401a25d99dbcc135957da6ccecc24358 104 Pfam PF00232 Glycosyl hydrolase family 1 3 101 6.1E-24 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 NPD12_2889 401a25d99dbcc135957da6ccecc24358 104 Gene3D G3DSA:3.20.20.80 1 104 7.6E-27 T 12-10-2018 NPD12_2889 401a25d99dbcc135957da6ccecc24358 104 SUPERFAMILY SSF51445 2 102 6.03E-27 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_2399 9618015b4273ea2db8aabdca44979447 149 SUPERFAMILY SSF51316 6 148 7.32E-60 T 12-10-2018 IPR011057 Mss4-like superfamily NPD12_2399 9618015b4273ea2db8aabdca44979447 149 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 6 133 36.697 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 NPD12_2399 9618015b4273ea2db8aabdca44979447 149 Gene3D G3DSA:2.170.150.20 2 149 6.6E-60 T 12-10-2018 NPD12_2399 9618015b4273ea2db8aabdca44979447 149 Pfam PF01641 SelR domain 12 132 4.9E-48 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 NPD12_2399 9618015b4273ea2db8aabdca44979447 149 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 141 1.0E-63 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 SUPERFAMILY SSF47729 1 90 8.1E-33 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.0E-34 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 SMART SM00411 1 90 5.8E-44 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 Gene3D G3DSA:4.10.520.10 1 92 3.3E-36 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 3.8E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 3.8E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 NPD12_4 75029c4c8d96fbb21156c42981cedb9a 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 3.8E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 NPD12_797 f5ce88324e970138217b4749955555c7 205 SUPERFAMILY SSF48498 111 195 5.78E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily NPD12_797 f5ce88324e970138217b4749955555c7 205 SUPERFAMILY SSF46689 8 65 1.28E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_797 f5ce88324e970138217b4749955555c7 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.7E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_797 f5ce88324e970138217b4749955555c7 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_797 f5ce88324e970138217b4749955555c7 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_797 f5ce88324e970138217b4749955555c7 205 Gene3D G3DSA:1.10.10.60 1 54 3.5E-20 T 12-10-2018 NPD12_797 f5ce88324e970138217b4749955555c7 205 Gene3D G3DSA:1.10.357.10 56 205 4.9E-30 T 12-10-2018 NPD12_2058 247cf092483de25aa959560d7a214585 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 125 1.2E-19 T 12-10-2018 IPR025664 Stage III sporulation protein AC/AD family NPD12_2058 247cf092483de25aa959560d7a214585 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 57 7.2E-12 T 12-10-2018 IPR025664 Stage III sporulation protein AC/AD family NPD12_2058 247cf092483de25aa959560d7a214585 127 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 127 9.5E-40 T 12-10-2018 IPR014211 Stage III sporulation protein AD NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 SUPERFAMILY SSF53474 3 269 7.52E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 Pfam PF00561 alpha/beta hydrolase fold 25 131 7.4E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.8E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 214 228 2.8E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.8E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 PRINTS PR00412 Epoxide hydrolase signature 245 267 1.8E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 PRINTS PR00412 Epoxide hydrolase signature 30 48 1.8E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 PRINTS PR00412 Epoxide hydrolase signature 50 65 1.8E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 PRINTS PR00412 Epoxide hydrolase signature 212 228 1.8E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_1031 0d530a98131d6c376c904b69c39984fd 270 Gene3D G3DSA:3.40.50.1820 1 269 4.0E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2956 03488577bad8a1501f33234e1c56c9ce 763 SUPERFAMILY SSF52540 202 755 2.8E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2956 03488577bad8a1501f33234e1c56c9ce 763 Gene3D G3DSA:1.10.10.160 435 513 1.3E-7 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily NPD12_2956 03488577bad8a1501f33234e1c56c9ce 763 Gene3D G3DSA:3.40.50.300 514 577 1.3E-7 T 12-10-2018 NPD12_2956 03488577bad8a1501f33234e1c56c9ce 763 Gene3D G3DSA:3.40.50.300 598 763 1.2E-47 T 12-10-2018 NPD12_2956 03488577bad8a1501f33234e1c56c9ce 763 Gene3D G3DSA:3.40.50.300 201 381 1.1E-14 T 12-10-2018 NPD12_2956 03488577bad8a1501f33234e1c56c9ce 763 Pfam PF13245 AAA domain 213 574 1.9E-12 T 12-10-2018 NPD12_1286 91f7696b873af09367d8dd66ed0bdf15 287 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 219 3.2E-63 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT NPD12_1286 91f7696b873af09367d8dd66ed0bdf15 287 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 6.5E-22 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 NPD12_1286 91f7696b873af09367d8dd66ed0bdf15 287 PIRSF PIRSF006483 2 287 1.0E-95 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT NPD12_1286 91f7696b873af09367d8dd66ed0bdf15 287 Gene3D G3DSA:3.30.70.120 197 271 5.7E-26 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal NPD12_3049 b9c778b23e2458dca5d213e873a22bf9 190 Pfam PF06810 Phage minor structural protein GP20 23 151 5.7E-35 T 12-10-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069 NPD12_3701 5838c412ba9ae9249aa62898f8058e81 795 SUPERFAMILY SSF81606 586 788 4.71E-16 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_3701 5838c412ba9ae9249aa62898f8058e81 795 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 34 792 0.0 T 12-10-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_3701 5838c412ba9ae9249aa62898f8058e81 795 SMART SM00331 578 791 1.4E-26 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_3701 5838c412ba9ae9249aa62898f8058e81 795 Gene3D G3DSA:3.60.40.10 573 793 6.4E-40 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_3701 5838c412ba9ae9249aa62898f8058e81 795 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 606 791 2.0E-30 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 NPD12_2464 6c6cade19b4e71355127b64e5be2980d 320 Gene3D G3DSA:3.90.1640.10 1 203 1.6E-58 T 12-10-2018 NPD12_2464 6c6cade19b4e71355127b64e5be2980d 320 SUPERFAMILY SSF64182 14 317 3.01E-64 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily NPD12_2464 6c6cade19b4e71355127b64e5be2980d 320 Gene3D G3DSA:3.10.310.30 204 319 1.5E-28 T 12-10-2018 NPD12_2464 6c6cade19b4e71355127b64e5be2980d 320 Pfam PF02272 DHHA1 domain 188 315 1.8E-12 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 NPD12_2464 6c6cade19b4e71355127b64e5be2980d 320 Pfam PF01368 DHH family 16 155 8.4E-13 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_2894 4b354bc5ad58d151be9a7bc29a674db6 151 SMART SM00644 5 132 9.5E-12 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_2894 4b354bc5ad58d151be9a7bc29a674db6 151 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 17 132 5.8E-23 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_2894 4b354bc5ad58d151be9a7bc29a674db6 151 Gene3D G3DSA:3.40.80.10 9 148 9.8E-42 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_2894 4b354bc5ad58d151be9a7bc29a674db6 151 SMART SM00701 6 126 4.9E-6 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_2894 4b354bc5ad58d151be9a7bc29a674db6 151 SUPERFAMILY SSF55846 15 135 3.14E-40 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 SMART SM00387 337 446 2.6E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 Gene3D G3DSA:1.10.287.130 217 296 5.3E-19 T 12-10-2018 NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 226 291 1.3E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 SUPERFAMILY SSF47384 216 292 1.49E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 SUPERFAMILY SSF55874 280 429 2.29E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 429 2.5E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 SMART SM00388 225 291 1.7E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1177 ce6fd7b56bca31922a56ab51ef017854 460 Gene3D G3DSA:3.30.565.10 297 446 8.2E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1724 281afa31e596f4da42ebaf553360de65 207 SUPERFAMILY SSF109635 1 88 5.89E-15 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily NPD12_1724 281afa31e596f4da42ebaf553360de65 207 Gene3D G3DSA:1.20.120.910 1 127 7.5E-33 T 12-10-2018 NPD12_1724 281afa31e596f4da42ebaf553360de65 207 SUPERFAMILY SSF57716 89 121 1.11E-9 T 12-10-2018 NPD12_1724 281afa31e596f4da42ebaf553360de65 207 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 87 119 9.0E-12 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 NPD12_1724 281afa31e596f4da42ebaf553360de65 207 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 6 165 1.5E-58 T 12-10-2018 IPR014240 Regulatory protein, YteA family NPD12_3546 862178699b11b328fe575cc58da6483c 228 Pfam PF00005 ABC transporter 18 165 3.4E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3546 862178699b11b328fe575cc58da6483c 228 SMART SM00382 27 214 4.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3546 862178699b11b328fe575cc58da6483c 228 SUPERFAMILY SSF52540 1 219 3.55E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3546 862178699b11b328fe575cc58da6483c 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3546 862178699b11b328fe575cc58da6483c 228 Gene3D G3DSA:3.40.50.300 1 224 3.9E-70 T 12-10-2018 NPD12_3546 862178699b11b328fe575cc58da6483c 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 2.1E-87 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 NPD12_350 a240ab17693cad08ad55ca95eb92c9ea 345 Pfam PF04245 37-kD nucleoid-associated bacterial protein 13 343 2.9E-75 T 12-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 NPD12_16 94300cd7e0bd8e213ce3ffee5d90e2a9 95 SUPERFAMILY SSF160537 1 85 9.55E-36 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 NPD12_16 94300cd7e0bd8e213ce3ffee5d90e2a9 95 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 93 28.93 T 12-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 NPD12_16 94300cd7e0bd8e213ce3ffee5d90e2a9 95 Pfam PF04026 SpoVG 1 81 1.1E-39 T 12-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 NPD12_16 94300cd7e0bd8e213ce3ffee5d90e2a9 95 Gene3D G3DSA:3.30.1120.40 1 95 3.6E-40 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 NPD12_2988 cc40ee0f0a63d030da371f98186b378e 342 SUPERFAMILY SSF109604 27 339 1.3E-72 T 12-10-2018 NPD12_2988 cc40ee0f0a63d030da371f98186b378e 342 Pfam PF01966 HD domain 75 188 1.6E-18 T 12-10-2018 IPR006674 HD domain NPD12_2988 cc40ee0f0a63d030da371f98186b378e 342 Gene3D G3DSA:1.10.3210.10 1 335 1.6E-99 T 12-10-2018 NPD12_2988 cc40ee0f0a63d030da371f98186b378e 342 Pfam PF13286 Phosphohydrolase-associated domain 247 331 2.2E-14 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain NPD12_2988 cc40ee0f0a63d030da371f98186b378e 342 SMART SM00471 71 199 4.3E-13 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_2988 cc40ee0f0a63d030da371f98186b378e 342 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 38 165 2.2E-45 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 NPD12_922 956fb18aaf7dd8b4b8c7586aa5ef6b31 202 Pfam PF06114 IrrE N-terminal-like domain 100 180 1.2E-13 T 12-10-2018 IPR010359 IrrE N-terminal-like domain NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 Pfam PF02743 Cache domain 37 268 7.4E-30 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 SUPERFAMILY SSF103190 110 163 1.62E-7 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 436 618 9.6E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 SUPERFAMILY SSF58104 329 665 8.72E-65 T 12-10-2018 NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 Gene3D G3DSA:1.10.287.950 363 665 1.2E-65 T 12-10-2018 NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 Gene3D G3DSA:3.30.450.20 141 272 4.7E-29 T 12-10-2018 NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 SMART SM00283 390 665 5.7E-60 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1926 3f060dc9027e2145cb585e581203fa12 667 Gene3D G3DSA:1.20.1480.50 273 362 6.9E-11 T 12-10-2018 NPD12_399 7fac191362c0b142001d5e9173906add 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 94 1.5E-22 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 NPD12_399 7fac191362c0b142001d5e9173906add 102 Gene3D G3DSA:3.40.50.2300 2 102 5.7E-37 T 12-10-2018 NPD12_399 7fac191362c0b142001d5e9173906add 102 SUPERFAMILY SSF52794 1 101 8.37E-37 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 NPD12_3451 33834da9bbba5c66cb1031dcc76e3516 152 Pfam PF00583 Acetyltransferase (GNAT) family 17 127 9.3E-22 T 12-10-2018 IPR000182 GNAT domain NPD12_3451 33834da9bbba5c66cb1031dcc76e3516 152 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 15 147 1.1E-43 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 NPD12_3451 33834da9bbba5c66cb1031dcc76e3516 152 SUPERFAMILY SSF55729 5 149 1.05E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_3451 33834da9bbba5c66cb1031dcc76e3516 152 Gene3D G3DSA:3.40.630.30 8 151 6.0E-40 T 12-10-2018 NPD12_413 ed481e22d5d33e5e9bd1ae582ea33f6b 244 SUPERFAMILY SSF56281 1 227 2.1E-32 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_413 ed481e22d5d33e5e9bd1ae582ea33f6b 244 Pfam PF00753 Metallo-beta-lactamase superfamily 24 185 2.2E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_413 ed481e22d5d33e5e9bd1ae582ea33f6b 244 SMART SM00849 21 219 1.4E-9 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_413 ed481e22d5d33e5e9bd1ae582ea33f6b 244 Gene3D G3DSA:3.60.15.10 1 240 2.0E-34 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 SUPERFAMILY SSF56003 277 842 1.44E-148 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 179 285 9.1E-23 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 Pfam PF01799 [2Fe-2S] binding domain 70 141 2.4E-23 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 52 2.9E-4 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 Gene3D G3DSA:1.10.150.120 78 150 5.1E-25 T 12-10-2018 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 302 792 3.4E-116 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 SMART SM01008 177 285 1.5E-35 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 Gene3D G3DSA:3.30.365.10 151 844 4.6E-183 T 12-10-2018 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 SUPERFAMILY SSF54292 7 75 1.31E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 SUPERFAMILY SSF54665 162 304 1.28E-35 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 Gene3D G3DSA:3.10.20.30 2 75 1.3E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 TIGRFAM TIGR03311 Se_dep_XDH: selenium-dependent xanthine dehydrogenase 2 849 0.0 T 12-10-2018 IPR017697 Selenium-dependent xanthine dehydrogenase NPD12_2933 0d700eb2dfcef94e84a961f22a21aa4a 851 SUPERFAMILY SSF47741 70 153 3.01E-26 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 SMART SM00481 14 81 4.8E-29 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 Pfam PF14579 Helix-hairpin-helix motif 829 917 8.3E-24 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 13 1065 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 Pfam PF02811 PHP domain 15 186 1.3E-53 T 12-10-2018 IPR004013 PHP domain GO:0003824 NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 Pfam PF01336 OB-fold nucleic acid binding domain 1028 1106 6.4E-8 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 Gene3D G3DSA:1.10.10.1600 459 536 9.8E-31 T 12-10-2018 NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 SUPERFAMILY SSF89550 14 276 1.29E-46 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 304 746 2.4E-175 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_3529 1a94eab416599df92c6023e48176e2bf 1185 Gene3D G3DSA:3.20.20.140 1 282 3.7E-114 T 12-10-2018 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 87 103 6.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 72 87 6.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 SUPERFAMILY SSF46689 5 54 1.97E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 Gene3D G3DSA:1.10.10.60 57 108 1.1E-12 T 12-10-2018 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 Gene3D G3DSA:1.10.10.60 3 56 3.7E-14 T 12-10-2018 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 57 99 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 Pfam PF12833 Helix-turn-helix domain 26 104 3.7E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 SMART SM00342 20 103 1.3E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1055 b08ce09dd46d4bad40260aefa1900fb1 365 SUPERFAMILY SSF46689 56 108 2.6E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 Pfam PF13509 S1 domain 73 132 5.5E-10 T 12-10-2018 IPR039566 Conserved virulence factor B, S1 domain NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 Pfam PF13509 S1 domain 4 66 2.5E-22 T 12-10-2018 IPR039566 Conserved virulence factor B, S1 domain NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 Gene3D G3DSA:2.40.50.140 147 215 1.3E-18 T 12-10-2018 NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 SMART SM00316 3 67 4.5 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 SMART SM00316 145 208 1.2E-11 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 SMART SM00316 72 133 22.0 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 SUPERFAMILY SSF50249 143 214 2.93E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 Gene3D G3DSA:1.10.10.10 216 278 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 PIRSF PIRSF012524 1 278 3.6E-77 T 12-10-2018 IPR014464 Conserved virulence factor B NPD12_1931 284a7760c27049ee4d2b371fd013f189 278 Pfam PF00575 S1 RNA binding domain 145 208 7.1E-7 T 12-10-2018 IPR003029 S1 domain GO:0003676 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Gene3D G3DSA:1.50.10.140 1303 1579 1.5E-7 T 12-10-2018 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 SUPERFAMILY SSF48208 2366 2881 6.05E-95 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 SUPERFAMILY SSF74650 2094 2357 2.67E-70 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2387 2813 1.7E-139 T 12-10-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Gene3D G3DSA:1.50.10.140 991 1128 6.2E-17 T 12-10-2018 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Gene3D G3DSA:1.50.10.10 2401 2813 1.4E-196 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 SMART SM01068 2094 2159 1.8E-33 T 12-10-2018 IPR009342 Putative carbohydrate binding domain NPD12_3476 f9aef34d478391e563635e08098043dc 2882 SMART SM01068 1592 1651 7.3E-16 T 12-10-2018 IPR009342 Putative carbohydrate binding domain NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Gene3D G3DSA:2.60.420.10 2396 2870 1.4E-196 T 12-10-2018 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Gene3D G3DSA:2.70.98.40 1597 1895 3.8E-78 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Gene3D G3DSA:2.70.98.40 2096 2392 1.7E-82 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily NPD12_3476 f9aef34d478391e563635e08098043dc 2882 SUPERFAMILY SSF74650 1602 1864 1.85E-69 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Pfam PF10091 Putative glucoamylase 1350 1564 3.3E-17 T 12-10-2018 IPR019282 Domain of unknown function DUF2329 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Pfam PF06165 Glycosyltransferase family 36 2117 2356 4.2E-78 T 12-10-2018 IPR010383 Glycosyl hydrolase 94 NPD12_3476 f9aef34d478391e563635e08098043dc 2882 Pfam PF06165 Glycosyltransferase family 36 1614 1860 2.3E-70 T 12-10-2018 IPR010383 Glycosyl hydrolase 94 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 Pfam PF08448 PAS fold 20 132 2.4E-7 T 12-10-2018 IPR013656 PAS fold-4 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 Gene3D G3DSA:3.30.450.20 8 157 1.1E-7 T 12-10-2018 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 SMART SM00448 168 281 1.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 Pfam PF00072 Response regulator receiver domain 170 281 3.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 Gene3D G3DSA:3.40.50.2300 158 296 2.7E-38 T 12-10-2018 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 SUPERFAMILY SSF52172 169 300 1.04E-33 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 SUPERFAMILY SSF47226 264 401 3.14E-14 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 Gene3D G3DSA:1.20.120.160 307 414 2.4E-10 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 NPD12_673 5c0ea556f2599f23fc8b6e4ba07736ac 415 Pfam PF01627 Hpt domain 334 380 3.8E-5 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 NPD12_1528 776c1e81556b1e64af6bd84cc23b9f29 235 SMART SM00914 192 229 4.0E-9 T 12-10-2018 IPR014957 IDEAL domain NPD12_1528 776c1e81556b1e64af6bd84cc23b9f29 235 Pfam PF08858 IDEAL domain 198 228 2.1E-6 T 12-10-2018 IPR014957 IDEAL domain NPD12_466 c517171910c9603386fd5b24d10869e7 345 SMART SM00342 253 337 4.9E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_466 c517171910c9603386fd5b24d10869e7 345 Pfam PF12833 Helix-turn-helix domain 260 337 9.7E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_466 c517171910c9603386fd5b24d10869e7 345 SUPERFAMILY SSF46689 292 339 1.43E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_466 c517171910c9603386fd5b24d10869e7 345 Gene3D G3DSA:1.10.10.60 236 341 8.5E-23 T 12-10-2018 NPD12_466 c517171910c9603386fd5b24d10869e7 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 306 321 2.0E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_466 c517171910c9603386fd5b24d10869e7 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 321 337 2.0E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 Pfam PF00534 Glycosyl transferases group 1 443 615 5.0E-10 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 Gene3D G3DSA:3.40.50.2000 452 620 1.1E-14 T 12-10-2018 NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 Gene3D G3DSA:3.90.550.10 1 259 3.7E-47 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 Pfam PF13439 Glycosyltransferase Family 4 277 431 8.1E-21 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 Gene3D G3DSA:3.40.50.2000 264 451 2.2E-29 T 12-10-2018 NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 SUPERFAMILY SSF53756 271 639 7.33E-48 T 12-10-2018 NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 Pfam PF00535 Glycosyl transferase family 2 6 171 8.8E-27 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_2232 d1084cfb00ee7228bd799fdf1e4edcd3 873 SUPERFAMILY SSF53448 3 226 2.67E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_1974 cb0606596f01eb254638f4bae2273a20 114 SUPERFAMILY SSF69118 6 112 6.67E-30 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 NPD12_1974 cb0606596f01eb254638f4bae2273a20 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 104 2.5E-22 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 NPD12_1974 cb0606596f01eb254638f4bae2273a20 114 Gene3D G3DSA:1.20.1290.10 1 114 1.1E-34 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 NPD12_1974 cb0606596f01eb254638f4bae2273a20 114 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 88 9.1E-16 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 NPD12_145 d88e522a1beaecfe10b6a5856592c86c 465 Gene3D G3DSA:3.30.9.10 86 284 1.5E-52 T 12-10-2018 NPD12_145 d88e522a1beaecfe10b6a5856592c86c 465 Gene3D G3DSA:1.10.10.1100 369 445 1.6E-19 T 12-10-2018 NPD12_145 d88e522a1beaecfe10b6a5856592c86c 465 Pfam PF01266 FAD dependent oxidoreductase 4 210 1.3E-29 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 NPD12_145 d88e522a1beaecfe10b6a5856592c86c 465 SUPERFAMILY SSF51905 2 360 1.46E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_145 d88e522a1beaecfe10b6a5856592c86c 465 Pfam PF04324 BFD-like [2Fe-2S] binding domain 382 436 5.7E-16 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain NPD12_145 d88e522a1beaecfe10b6a5856592c86c 465 Gene3D G3DSA:3.50.50.60 4 213 1.5E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1418 209b71a19306a619ff8e2138dc2aa017 190 Gene3D G3DSA:1.20.1260.10 1 188 1.3E-64 T 12-10-2018 IPR012347 Ferritin-like NPD12_1418 209b71a19306a619ff8e2138dc2aa017 190 SUPERFAMILY SSF47240 1 189 1.8E-70 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_1418 209b71a19306a619ff8e2138dc2aa017 190 Pfam PF05067 Manganese containing catalase 1 183 2.8E-60 T 12-10-2018 IPR007760 Manganese catalase NPD12_3616 b2a4f16352873b4416a68cbd3c9d2b79 93 SUPERFAMILY SSF50104 4 82 1.44E-14 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily NPD12_3616 b2a4f16352873b4416a68cbd3c9d2b79 93 Gene3D G3DSA:2.30.30.30 4 92 1.0E-8 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 NPD12_282 2f1aefe78d2c99551cb9e7c6c395bd85 456 Pfam PF03413 Peptidase propeptide and YPEB domain 383 438 1.6E-4 T 12-10-2018 IPR025711 PepSY domain NPD12_282 2f1aefe78d2c99551cb9e7c6c395bd85 456 Pfam PF14620 YpeB sporulation 17 378 4.4E-128 T 12-10-2018 IPR014239 Spore germination YpeB GO:0009847 NPD12_282 2f1aefe78d2c99551cb9e7c6c395bd85 456 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 7 446 1.0E-158 T 12-10-2018 IPR014239 Spore germination YpeB GO:0009847 NPD12_1621 86c7f46fb54462877a2357330b617a64 529 PIRSF PIRSF002741 3 527 1.7E-166 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 NPD12_1621 86c7f46fb54462877a2357330b617a64 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 440 4.0E-91 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain NPD12_1621 86c7f46fb54462877a2357330b617a64 529 Gene3D G3DSA:3.90.76.10 70 184 3.2E-163 T 12-10-2018 NPD12_1621 86c7f46fb54462877a2357330b617a64 529 SUPERFAMILY SSF53850 40 521 1.03E-133 T 12-10-2018 NPD12_1621 86c7f46fb54462877a2357330b617a64 529 Gene3D G3DSA:3.40.190.10 56 508 3.2E-163 T 12-10-2018 NPD12_1621 86c7f46fb54462877a2357330b617a64 529 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 109 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site NPD12_1621 86c7f46fb54462877a2357330b617a64 529 Gene3D G3DSA:3.10.105.10 278 493 3.2E-163 T 12-10-2018 NPD12_1066 87f1db7ba4f8920eafcb556e627f9e7f 216 Gene3D G3DSA:2.160.10.10 1 215 1.1E-68 T 12-10-2018 NPD12_1066 87f1db7ba4f8920eafcb556e627f9e7f 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 125 153 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 NPD12_1066 87f1db7ba4f8920eafcb556e627f9e7f 216 SUPERFAMILY SSF51161 57 211 1.08E-43 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_1066 87f1db7ba4f8920eafcb556e627f9e7f 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 151 5.2E-9 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_3096 e0b2bee4d0250686c4dd8437fbfa2d44 479 Pfam PF10150 Ribonuclease E/G family 105 370 3.9E-79 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 NPD12_3096 e0b2bee4d0250686c4dd8437fbfa2d44 479 Gene3D G3DSA:2.40.50.140 30 109 6.3E-17 T 12-10-2018 NPD12_3096 e0b2bee4d0250686c4dd8437fbfa2d44 479 SUPERFAMILY SSF50249 38 109 4.52E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3096 e0b2bee4d0250686c4dd8437fbfa2d44 479 SMART SM00316 36 103 4.8E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 NPD12_3096 e0b2bee4d0250686c4dd8437fbfa2d44 479 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 399 3.3E-101 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 NPD12_1588 686e619943838f46beef9a0b963d3290 676 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 528 650 6.1E-51 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_1588 686e619943838f46beef9a0b963d3290 676 Gene3D G3DSA:2.70.70.10 514 676 6.9E-57 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_1588 686e619943838f46beef9a0b963d3290 676 Pfam PF00367 phosphotransferase system, EIIB 432 464 4.1E-12 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_1588 686e619943838f46beef9a0b963d3290 676 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 504 4.9E-243 T 12-10-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 NPD12_1588 686e619943838f46beef9a0b963d3290 676 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 530 649 2.0E-45 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_1588 686e619943838f46beef9a0b963d3290 676 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 591 603 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_1588 686e619943838f46beef9a0b963d3290 676 SUPERFAMILY SSF55604 429 502 3.27E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1588 686e619943838f46beef9a0b963d3290 676 SUPERFAMILY SSF51261 520 672 2.09E-54 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_1588 686e619943838f46beef9a0b963d3290 676 Pfam PF02378 Phosphotransferase system, EIIC 13 344 1.2E-92 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_1588 686e619943838f46beef9a0b963d3290 676 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 404 488 5.5E-21 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 NPD12_1588 686e619943838f46beef9a0b963d3290 676 Gene3D G3DSA:3.30.1360.60 425 505 2.8E-28 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_1168 db9ac728e04451420e33da9a03ec9960 147 SUPERFAMILY SSF55729 11 145 5.93E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1168 db9ac728e04451420e33da9a03ec9960 147 Gene3D G3DSA:3.40.630.30 1 147 7.1E-37 T 12-10-2018 NPD12_1168 db9ac728e04451420e33da9a03ec9960 147 Pfam PF13508 Acetyltransferase (GNAT) domain 47 113 1.8E-10 T 12-10-2018 IPR000182 GNAT domain NPD12_1777 75dab61b46457d35c70a4d0f157aa397 370 Pfam PF01381 Helix-turn-helix 10 64 9.7E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1777 75dab61b46457d35c70a4d0f157aa397 370 Gene3D G3DSA:1.25.40.10 66 315 4.0E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1777 75dab61b46457d35c70a4d0f157aa397 370 SUPERFAMILY SSF47413 3 68 3.84E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1777 75dab61b46457d35c70a4d0f157aa397 370 SUPERFAMILY SSF48452 64 235 7.3E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1777 75dab61b46457d35c70a4d0f157aa397 370 SMART SM00530 9 64 4.2E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1777 75dab61b46457d35c70a4d0f157aa397 370 Gene3D G3DSA:1.10.260.40 2 65 1.7E-21 T 12-10-2018 NPD12_3205 2c69cb2eefefe8d065d9d5a044981a61 367 Gene3D G3DSA:3.40.50.2000 166 350 5.8E-62 T 12-10-2018 NPD12_3205 2c69cb2eefefe8d065d9d5a044981a61 367 Pfam PF00534 Glycosyl transferases group 1 179 341 6.3E-33 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_3205 2c69cb2eefefe8d065d9d5a044981a61 367 Gene3D G3DSA:3.40.50.2000 65 363 5.8E-62 T 12-10-2018 NPD12_3205 2c69cb2eefefe8d065d9d5a044981a61 367 Pfam PF13439 Glycosyltransferase Family 4 62 169 1.4E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_3205 2c69cb2eefefe8d065d9d5a044981a61 367 SUPERFAMILY SSF53756 1 366 6.63E-72 T 12-10-2018 NPD12_38 01ffaedef3f34373988ec88f35aad044 189 SMART SM00909 81 168 1.2E-24 T 12-10-2018 IPR019606 GerMN domain NPD12_38 01ffaedef3f34373988ec88f35aad044 189 Pfam PF10646 Sporulation and spore germination 54 163 2.8E-19 T 12-10-2018 IPR019606 GerMN domain NPD12_1403 64a30a07ebf918ae57f01511d29b874a 194 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 6 183 1.2E-15 T 12-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 NPD12_1403 64a30a07ebf918ae57f01511d29b874a 194 Gene3D G3DSA:3.40.50.1000 1 176 4.9E-13 T 12-10-2018 IPR023214 HAD superfamily NPD12_1403 64a30a07ebf918ae57f01511d29b874a 194 PIRSF PIRSF021362 3 193 4.8E-60 T 12-10-2018 IPR009206 Nucleotidase, putative NPD12_1403 64a30a07ebf918ae57f01511d29b874a 194 SUPERFAMILY SSF56784 5 164 4.04E-19 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_655 121fa761f6db17f4a89650645c460465 360 SUPERFAMILY SSF69572 176 335 3.66E-6 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 NPD12_655 121fa761f6db17f4a89650645c460465 360 Gene3D G3DSA:3.40.50.720 166 334 5.3E-16 T 12-10-2018 NPD12_655 121fa761f6db17f4a89650645c460465 360 TIGRFAM TIGR03603 cyclo_dehy_ocin: thiazole/oxazole-forming peptide maturase, SagC family component 30 356 6.8E-136 T 12-10-2018 IPR019892 Thiazole/oxazole-forming peptide maturase, SagC family component NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 Gene3D G3DSA:3.40.50.300 179 505 3.7E-57 T 12-10-2018 NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 SUPERFAMILY SSF52540 189 499 6.74E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 Gene3D G3DSA:3.30.230.10 8 170 2.2E-15 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 Pfam PF01078 Magnesium chelatase, subunit ChlI 191 396 1.8E-87 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 404 499 2.8E-29 T 12-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 SUPERFAMILY SSF54211 9 167 3.68E-35 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 499 8.9E-179 T 12-10-2018 IPR004482 Mg chelatase-related protein NPD12_2487 a61aa614732b0b1d37b0daa69faad880 507 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 142 7.3E-49 T 12-10-2018 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 SUPERFAMILY SSF51306 31 201 1.71E-42 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 Pfam PF10502 Signal peptidase, peptidase S26 96 188 1.9E-10 T 12-10-2018 IPR019533 Peptidase S26 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 Gene3D G3DSA:2.10.109.10 89 201 2.4E-30 T 12-10-2018 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 ProSitePatterns PS00760 Signal peptidases I lysine active site. 111 123 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 196 5.1E-44 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 Gene3D G3DSA:2.10.109.10 32 78 6.2E-6 T 12-10-2018 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 155 174 1.7E-15 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 30 46 1.7E-15 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 109 121 1.7E-15 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 NPD12_753 0208306d6d8ebb42f3ea5cd5b5582654 202 ProSitePatterns PS00761 Signal peptidases I signature 3. 160 173 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 Gene3D G3DSA:1.10.287.130 132 256 3.2E-14 T 12-10-2018 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 197 260 8.2E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 SMART SM00388 194 260 5.0E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 SMART SM00387 305 415 1.5E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1559 328449139f2eefed13220779c2cd7d92 415 SUPERFAMILY SSF55874 251 413 1.09E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1559 328449139f2eefed13220779c2cd7d92 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 411 1.2E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_1559 328449139f2eefed13220779c2cd7d92 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 2.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 370 2.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 395 2.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 414 2.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1559 328449139f2eefed13220779c2cd7d92 415 Gene3D G3DSA:3.30.565.10 266 415 6.7E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1559 328449139f2eefed13220779c2cd7d92 415 SUPERFAMILY SSF47384 182 260 1.43E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_225 1841d771785254c66593e3718c504711 289 Pfam PF01522 Polysaccharide deacetylase 121 245 8.0E-35 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 NPD12_225 1841d771785254c66593e3718c504711 289 Gene3D G3DSA:3.20.20.370 62 284 2.6E-79 T 12-10-2018 NPD12_225 1841d771785254c66593e3718c504711 289 SUPERFAMILY SSF88713 84 267 5.68E-50 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 9 255 30.851 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 SUPERFAMILY SSF53613 7 261 7.02E-59 T 12-10-2018 IPR029056 Ribokinase-like NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 PIRSF PIRSF000513 1 263 2.3E-87 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 7 252 1.5E-86 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 Gene3D G3DSA:3.40.1190.20 1 260 4.3E-92 T 12-10-2018 IPR029056 Ribokinase-like NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 15 22 9.9E-32 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 85 102 9.9E-32 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 116 130 9.9E-32 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 59 67 9.9E-32 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 28 49 9.9E-32 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 160 177 9.9E-32 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_618 84edec3e3c17118e3914b6285ea3999a 263 Pfam PF02110 Hydroxyethylthiazole kinase family 7 250 1.1E-82 T 12-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 NPD12_1216 bbad2b04160326e2d4483416c5bcd282 229 Pfam PF13545 Crp-like helix-turn-helix domain 154 218 3.2E-11 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_1216 bbad2b04160326e2d4483416c5bcd282 229 SUPERFAMILY SSF51206 25 139 2.62E-25 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like NPD12_1216 bbad2b04160326e2d4483416c5bcd282 229 Pfam PF00027 Cyclic nucleotide-binding domain 35 117 3.3E-10 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain NPD12_1216 bbad2b04160326e2d4483416c5bcd282 229 SUPERFAMILY SSF46785 152 221 1.33E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1216 bbad2b04160326e2d4483416c5bcd282 229 Gene3D G3DSA:2.60.120.10 16 144 8.6E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1216 bbad2b04160326e2d4483416c5bcd282 229 Gene3D G3DSA:1.10.10.10 150 222 1.5E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 Gene3D G3DSA:3.40.1390.20 1 127 6.2E-37 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 Pfam PF02603 HPr Serine kinase N terminus 2 124 1.6E-38 T 12-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 Gene3D G3DSA:3.40.50.300 128 307 1.6E-62 T 12-10-2018 NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 SUPERFAMILY SSF75138 3 128 3.53E-32 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 303 38.386 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 298 7.5E-105 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 Pfam PF07475 HPr Serine kinase C-terminal domain 126 288 2.0E-68 T 12-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 NPD12_2654 05d5637502589e6e0888caf29af59bd6 307 SUPERFAMILY SSF53795 132 291 8.85E-37 T 12-10-2018 NPD12_2074 43b5e6765eff9e911b49c71f018703e2 396 Pfam PF00482 Type II secretion system (T2SS), protein F 64 186 5.0E-19 T 12-10-2018 IPR018076 Type II secretion system F domain NPD12_2074 43b5e6765eff9e911b49c71f018703e2 396 Pfam PF00482 Type II secretion system (T2SS), protein F 266 388 1.4E-20 T 12-10-2018 IPR018076 Type II secretion system F domain NPD12_2074 43b5e6765eff9e911b49c71f018703e2 396 Gene3D G3DSA:1.20.81.30 50 165 1.3E-21 T 12-10-2018 NPD12_2074 43b5e6765eff9e911b49c71f018703e2 396 PRINTS PR00812 Bacterial general secretion pathway protein F signature 361 375 2.7E-12 T 12-10-2018 IPR003004 GspF/PilC family NPD12_2074 43b5e6765eff9e911b49c71f018703e2 396 PRINTS PR00812 Bacterial general secretion pathway protein F signature 377 396 2.7E-12 T 12-10-2018 IPR003004 GspF/PilC family NPD12_2074 43b5e6765eff9e911b49c71f018703e2 396 PRINTS PR00812 Bacterial general secretion pathway protein F signature 158 186 2.7E-12 T 12-10-2018 IPR003004 GspF/PilC family NPD12_2074 43b5e6765eff9e911b49c71f018703e2 396 Gene3D G3DSA:1.20.81.30 249 362 6.9E-22 T 12-10-2018 NPD12_1670 c516aaa28638a5a7dc68273cca057ac7 137 SUPERFAMILY SSF55811 17 135 3.38E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 NPD12_1670 c516aaa28638a5a7dc68273cca057ac7 137 Pfam PF00293 NUDIX domain 32 133 2.4E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 NPD12_1670 c516aaa28638a5a7dc68273cca057ac7 137 Gene3D G3DSA:3.90.79.10 3 137 7.3E-35 T 12-10-2018 NPD12_1670 c516aaa28638a5a7dc68273cca057ac7 137 ProSitePatterns PS00893 Nudix box signature. 63 84 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 NPD12_3025 7eb765b6476527e05546ab0e5d7b6961 522 Pfam PF13175 AAA ATPase domain 1 193 6.7E-8 T 12-10-2018 NPD12_3025 7eb765b6476527e05546ab0e5d7b6961 522 Gene3D G3DSA:3.40.50.300 1 305 1.5E-19 T 12-10-2018 NPD12_3025 7eb765b6476527e05546ab0e5d7b6961 522 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 237 284 7.1E-10 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_3025 7eb765b6476527e05546ab0e5d7b6961 522 SUPERFAMILY SSF52540 1 288 1.35E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_806 64023e782544e4e73533917fa51714a8 407 SUPERFAMILY SSF55031 212 319 1.31E-21 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain NPD12_806 64023e782544e4e73533917fa51714a8 407 SUPERFAMILY SSF53187 2 405 1.63E-81 T 12-10-2018 NPD12_806 64023e782544e4e73533917fa51714a8 407 Gene3D G3DSA:3.30.70.360 212 323 8.6E-129 T 12-10-2018 NPD12_806 64023e782544e4e73533917fa51714a8 407 Pfam PF07687 Peptidase dimerisation domain 211 308 8.9E-6 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_806 64023e782544e4e73533917fa51714a8 407 Gene3D G3DSA:3.40.630.10 16 399 8.6E-129 T 12-10-2018 NPD12_806 64023e782544e4e73533917fa51714a8 407 PIRSF PIRSF001235 2 407 3.3E-127 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 NPD12_806 64023e782544e4e73533917fa51714a8 407 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 7 403 7.3E-120 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 NPD12_806 64023e782544e4e73533917fa51714a8 407 Pfam PF01546 Peptidase family M20/M25/M40 78 402 4.6E-27 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_259 241e678f7229e99cff894895c3ad16b7 268 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 259 1.8E-83 T 12-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 NPD12_259 241e678f7229e99cff894895c3ad16b7 268 SUPERFAMILY SSF52402 18 219 8.6E-34 T 12-10-2018 NPD12_259 241e678f7229e99cff894895c3ad16b7 268 Gene3D G3DSA:3.40.50.620 2 166 9.7E-27 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_259 241e678f7229e99cff894895c3ad16b7 268 Pfam PF02540 NAD synthase 16 83 2.0E-6 T 12-10-2018 IPR022310 NAD/GMP synthase NPD12_259 241e678f7229e99cff894895c3ad16b7 268 PIRSF PIRSF006661 1 268 1.1E-103 T 12-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 NPD12_1256 11e2dc66f6b8037ba26e2d0c20a3f81c 308 Pfam PF04389 Peptidase family M28 102 299 1.7E-37 T 12-10-2018 IPR007484 Peptidase M28 NPD12_1256 11e2dc66f6b8037ba26e2d0c20a3f81c 308 SUPERFAMILY SSF53187 24 300 2.24E-47 T 12-10-2018 NPD12_1256 11e2dc66f6b8037ba26e2d0c20a3f81c 308 Gene3D G3DSA:3.40.630.10 2 302 5.4E-54 T 12-10-2018 NPD12_3091 e450db87b30834ef1a45096a5de87759 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 2.9E-25 T 12-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 NPD12_3091 e450db87b30834ef1a45096a5de87759 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 85 7.7E-22 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 NPD12_3091 e450db87b30834ef1a45096a5de87759 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 95 7.0E-29 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 NPD12_3091 e450db87b30834ef1a45096a5de87759 97 Gene3D G3DSA:3.30.110.60 1 97 1.5E-34 T 12-10-2018 IPR035920 YhbY-like superfamily NPD12_3091 e450db87b30834ef1a45096a5de87759 97 SMART SM01103 2 85 2.2E-39 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 NPD12_3091 e450db87b30834ef1a45096a5de87759 97 SUPERFAMILY SSF75471 1 95 5.49E-30 T 12-10-2018 IPR035920 YhbY-like superfamily NPD12_1130 8106f185a5ed5475cdfe6c9e0743cb1d 182 Gene3D G3DSA:3.40.630.30 14 181 7.5E-37 T 12-10-2018 NPD12_1130 8106f185a5ed5475cdfe6c9e0743cb1d 182 SUPERFAMILY SSF55729 15 181 3.09E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1130 8106f185a5ed5475cdfe6c9e0743cb1d 182 Pfam PF00583 Acetyltransferase (GNAT) family 61 153 6.4E-15 T 12-10-2018 IPR000182 GNAT domain NPD12_2087 c6347de54a955059156507612edd5265 233 SUPERFAMILY SSF52172 3 128 8.54E-39 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2087 c6347de54a955059156507612edd5265 233 Gene3D G3DSA:3.40.50.2300 2 130 4.5E-37 T 12-10-2018 NPD12_2087 c6347de54a955059156507612edd5265 233 SMART SM00448 4 115 3.6E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2087 c6347de54a955059156507612edd5265 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 2.6E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2087 c6347de54a955059156507612edd5265 233 SUPERFAMILY SSF46894 132 231 3.97E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_2087 c6347de54a955059156507612edd5265 233 Pfam PF00072 Response regulator receiver domain 6 116 3.5E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2087 c6347de54a955059156507612edd5265 233 SMART SM00862 155 231 2.1E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2087 c6347de54a955059156507612edd5265 233 Gene3D G3DSA:1.10.10.10 135 233 8.2E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_426 665889be0be6a031fdf03133e87999e6 286 Gene3D G3DSA:3.30.240.20 80 154 1.1E-21 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily NPD12_426 665889be0be6a031fdf03133e87999e6 286 Gene3D G3DSA:3.30.240.20 170 227 3.0E-14 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily NPD12_426 665889be0be6a031fdf03133e87999e6 286 Pfam PF07870 Protein of unknown function (DUF1657) 237 284 5.5E-16 T 12-10-2018 IPR012452 Protein of unknown function DUF1657 NPD12_426 665889be0be6a031fdf03133e87999e6 286 Pfam PF04239 Protein of unknown function (DUF421) 89 204 2.4E-28 T 12-10-2018 IPR007353 Protein of unknown function DUF421 NPD12_2337 5229701da85a76f9b45c76fcc98d2c4d 175 Pfam PF03358 NADPH-dependent FMN reductase 33 91 1.8E-5 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_2337 5229701da85a76f9b45c76fcc98d2c4d 175 SUPERFAMILY SSF52218 32 95 5.12E-11 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2337 5229701da85a76f9b45c76fcc98d2c4d 175 Gene3D G3DSA:3.40.50.360 6 170 7.4E-14 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 Pfam PF13393 Histidyl-tRNA synthetase 8 306 2.1E-47 T 12-10-2018 NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 SUPERFAMILY SSF52954 322 411 8.02E-23 T 12-10-2018 NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 Gene3D G3DSA:3.40.50.800 319 411 3.9E-24 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 413 33.004 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 Gene3D G3DSA:3.30.930.10 1 318 1.7E-113 T 12-10-2018 NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 PIRSF PIRSF001549 1 413 1.6E-122 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 Pfam PF03129 Anticodon binding domain 333 412 1.5E-13 T 12-10-2018 IPR004154 Anticodon-binding NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 SUPERFAMILY SSF55681 4 313 1.39E-96 T 12-10-2018 NPD12_3164 e3f620c7af253d2ee29e0e3a6ee0d1d6 415 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 403 2.1E-153 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 NPD12_2822 e4671b2a7811a1ca2602905288e898b1 298 SUPERFAMILY SSF52540 2 222 1.25E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2822 e4671b2a7811a1ca2602905288e898b1 298 Gene3D G3DSA:3.40.50.300 1 238 2.9E-54 T 12-10-2018 NPD12_2822 e4671b2a7811a1ca2602905288e898b1 298 Pfam PF00005 ABC transporter 17 155 2.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2822 e4671b2a7811a1ca2602905288e898b1 298 SMART SM00382 26 212 3.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2360 0095641b20681d4f35d1021a126c4278 392 Gene3D G3DSA:3.40.1710.10 46 182 1.0E-6 T 12-10-2018 NPD12_2360 0095641b20681d4f35d1021a126c4278 392 Pfam PF12698 ABC-2 family transporter protein 20 376 1.1E-33 T 12-10-2018 NPD12_2775 0cb4aad8143c0a2b13d57f70b6168412 93 SUPERFAMILY SSF101498 1 88 5.23E-14 T 12-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily NPD12_2775 0cb4aad8143c0a2b13d57f70b6168412 93 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 87 2.9E-12 T 12-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal NPD12_2775 0cb4aad8143c0a2b13d57f70b6168412 93 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 89 4.5E-11 T 12-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 NPD12_941 a6721930f49e0dcc126f4bed499d92c5 67 Pfam PF13783 Domain of unknown function (DUF4177) 3 62 1.6E-9 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 NPD12_2481 e7564f884edeff36f2ebdf87c19aa3c7 238 Pfam PF00696 Amino acid kinase family 7 213 1.1E-28 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 NPD12_2481 e7564f884edeff36f2ebdf87c19aa3c7 238 Gene3D G3DSA:3.40.1160.10 1 238 9.6E-79 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_2481 e7564f884edeff36f2ebdf87c19aa3c7 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 235 4.7E-98 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 NPD12_2481 e7564f884edeff36f2ebdf87c19aa3c7 238 PIRSF PIRSF005650 1 238 1.4E-94 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 NPD12_2481 e7564f884edeff36f2ebdf87c19aa3c7 238 SUPERFAMILY SSF53633 4 236 1.44E-71 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily NPD12_2481 e7564f884edeff36f2ebdf87c19aa3c7 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 235 44.398 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 NPD12_251 a090c6c2cdbc822265bbcf18f497cd0b 224 Gene3D G3DSA:1.10.1900.10 5 88 1.6E-6 T 12-10-2018 NPD12_251 a090c6c2cdbc822265bbcf18f497cd0b 224 Pfam PF06304 Protein of unknown function (DUF1048) 16 90 2.7E-7 T 12-10-2018 IPR008316 Uncharacterised conserved protein UCP029876 NPD12_251 a090c6c2cdbc822265bbcf18f497cd0b 224 SUPERFAMILY SSF158560 1 100 7.32E-24 T 12-10-2018 NPD12_1747 acd17e98127b64c23755b286da607295 211 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 208 1.4E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1747 acd17e98127b64c23755b286da607295 211 Gene3D G3DSA:1.10.3720.10 1 211 4.9E-50 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1747 acd17e98127b64c23755b286da607295 211 SUPERFAMILY SSF161098 4 196 1.05E-43 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 SMART SM00471 325 431 1.7E-12 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 513 2.6E-237 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 SUPERFAMILY SSF54791 201 297 6.65E-18 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 Gene3D G3DSA:3.30.1370.10 200 295 3.7E-9 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 Hamap MF_00335 Ribonuclease Y [rny]. 5 513 25.593 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 Pfam PF12072 Domain of unknown function (DUF3552) 6 198 4.5E-67 T 12-10-2018 IPR022711 Ribonuclease Y, N-terminal NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 SUPERFAMILY SSF109604 310 466 2.24E-31 T 12-10-2018 NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 Pfam PF00013 KH domain 206 263 3.4E-7 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 TIGRFAM TIGR00277 HDIG: HDIG domain 325 402 8.2E-22 T 12-10-2018 IPR006675 HDIG domain NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 SMART SM00322 201 268 3.2E-8 T 12-10-2018 IPR004087 K Homology domain GO:0003676 NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 Pfam PF01966 HD domain 330 421 4.9E-19 T 12-10-2018 IPR006674 HD domain NPD12_2451 09adac0ce10abf9b710401c2005f8c81 513 Gene3D G3DSA:1.10.3210.10 310 464 4.6E-19 T 12-10-2018 NPD12_523 3ab46ce7faf1dcdcb6a652372f5cc0ff 446 PIRSF PIRSF006603 2 446 2.6E-73 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_523 3ab46ce7faf1dcdcb6a652372f5cc0ff 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 408 6.4E-66 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_523 3ab46ce7faf1dcdcb6a652372f5cc0ff 446 Pfam PF01554 MatE 16 179 9.1E-26 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_523 3ab46ce7faf1dcdcb6a652372f5cc0ff 446 Pfam PF01554 MatE 243 405 3.4E-28 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2372 7f51a9ce757fba8dd1fcfd26f912b8c8 101 PIRSF PIRSF002599 5 100 3.3E-12 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 NPD12_2372 7f51a9ce757fba8dd1fcfd26f912b8c8 101 Pfam PF06961 Protein of unknown function (DUF1294) 26 80 2.3E-25 T 12-10-2018 IPR010718 Protein of unknown function DUF1294 NPD12_1217 646dee9ebb330eccb3e0fde10b759c26 194 Gene3D G3DSA:3.40.50.880 1 191 1.4E-37 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1217 646dee9ebb330eccb3e0fde10b759c26 194 Pfam PF01965 DJ-1/PfpI family 2 177 1.4E-26 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 NPD12_1217 646dee9ebb330eccb3e0fde10b759c26 194 SUPERFAMILY SSF52317 1 192 2.66E-36 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_3237 fb7d81df668635a55250f00b5fe3f9cd 196 SUPERFAMILY SSF102829 4 81 3.14E-17 T 12-10-2018 IPR036192 Cell division protein ZapA-like superfamily NPD12_3237 fb7d81df668635a55250f00b5fe3f9cd 196 Pfam PF05164 Cell division protein ZapA 4 127 5.8E-13 T 12-10-2018 IPR007838 Cell division protein ZapA-like NPD12_2253 13c1f921133d9192d2f4efee36669b9c 497 Pfam PF00171 Aldehyde dehydrogenase family 12 273 3.7E-25 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 NPD12_2253 13c1f921133d9192d2f4efee36669b9c 497 Gene3D G3DSA:3.40.605.10 17 445 5.8E-159 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 NPD12_2253 13c1f921133d9192d2f4efee36669b9c 497 Gene3D G3DSA:3.40.309.10 223 407 5.8E-159 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 NPD12_2253 13c1f921133d9192d2f4efee36669b9c 497 SUPERFAMILY SSF53720 10 448 4.06E-71 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 NPD12_1937 e8f4d41973b9bfa92b5b8145d9b7d9af 284 Pfam PF00072 Response regulator receiver domain 6 116 7.8E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1937 e8f4d41973b9bfa92b5b8145d9b7d9af 284 Gene3D G3DSA:3.40.50.2300 1 133 2.8E-33 T 12-10-2018 NPD12_1937 e8f4d41973b9bfa92b5b8145d9b7d9af 284 Gene3D G3DSA:3.40.1550.10 134 280 8.6E-26 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_1937 e8f4d41973b9bfa92b5b8145d9b7d9af 284 SMART SM00448 4 116 1.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1937 e8f4d41973b9bfa92b5b8145d9b7d9af 284 Pfam PF13690 Chemotaxis phosphatase CheX 170 256 1.4E-14 T 12-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain NPD12_1937 e8f4d41973b9bfa92b5b8145d9b7d9af 284 SUPERFAMILY SSF52172 1 128 2.13E-32 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1937 e8f4d41973b9bfa92b5b8145d9b7d9af 284 SUPERFAMILY SSF103039 131 279 2.88E-22 T 12-10-2018 IPR028976 CheC-like superfamily NPD12_1255 a90113131f4939f408f93a970198df2a 268 Gene3D G3DSA:3.60.15.10 1 264 5.9E-75 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1255 a90113131f4939f408f93a970198df2a 268 Pfam PF00753 Metallo-beta-lactamase superfamily 21 80 2.6E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_1255 a90113131f4939f408f93a970198df2a 268 SUPERFAMILY SSF56281 13 244 1.05E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1255 a90113131f4939f408f93a970198df2a 268 SMART SM00849 21 241 0.006 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_3389 5debfa8368c373019eb8c4fef73678cc 156 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 145 5.8E-29 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 NPD12_3389 5debfa8368c373019eb8c4fef73678cc 156 Gene3D G3DSA:3.60.21.10 1 156 1.2E-42 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like NPD12_3389 5debfa8368c373019eb8c4fef73678cc 156 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 149 1.4E-33 T 12-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 NPD12_3389 5debfa8368c373019eb8c4fef73678cc 156 SUPERFAMILY SSF56300 2 154 8.2E-41 T 12-10-2018 NPD12_1329 0c9d6838ce1118bd2837e813fef859a7 66 Pfam PF14056 Domain of unknown function (DUF4250) 11 63 4.4E-22 T 12-10-2018 IPR025346 Protein of unknown function DUF4250 NPD12_2356 66f8b62934aba2b2203ead04bc8e570a 342 Gene3D G3DSA:3.90.1150.10 6 330 1.7E-108 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_2356 66f8b62934aba2b2203ead04bc8e570a 342 Gene3D G3DSA:3.40.640.10 13 250 1.7E-108 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2356 66f8b62934aba2b2203ead04bc8e570a 342 SUPERFAMILY SSF53383 1 340 2.31E-72 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2356 66f8b62934aba2b2203ead04bc8e570a 342 Pfam PF01212 Beta-eliminating lyase 15 287 6.4E-35 T 12-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 NPD12_2017 85bd2d5ff4d41958979464ea835db094 271 SUPERFAMILY SSF53167 3 271 5.76E-96 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 NPD12_2017 85bd2d5ff4d41958979464ea835db094 271 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 268 1.8E-110 T 12-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 NPD12_2017 85bd2d5ff4d41958979464ea835db094 271 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 268 9.8E-108 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 NPD12_2017 85bd2d5ff4d41958979464ea835db094 271 Gene3D G3DSA:3.40.50.1580 2 270 4.9E-114 T 12-10-2018 NPD12_2017 85bd2d5ff4d41958979464ea835db094 271 Pfam PF01048 Phosphorylase superfamily 23 268 1.2E-56 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 NPD12_2017 85bd2d5ff4d41958979464ea835db094 271 PIRSF PIRSF000477 2 271 2.4E-111 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 NPD12_3006 e6b85b1886237082c8c735f06c3b9968 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 4 310 1.9E-104 T 12-10-2018 NPD12_3006 e6b85b1886237082c8c735f06c3b9968 312 Gene3D G3DSA:3.40.50.150 118 311 6.5E-63 T 12-10-2018 NPD12_3006 e6b85b1886237082c8c735f06c3b9968 312 SUPERFAMILY SSF53335 96 307 5.09E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3006 e6b85b1886237082c8c735f06c3b9968 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 5 311 35.596 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 NPD12_3006 e6b85b1886237082c8c735f06c3b9968 312 PIRSF PIRSF000401 3 312 4.2E-114 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 NPD12_3006 e6b85b1886237082c8c735f06c3b9968 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 5 304 7.3E-80 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 NPD12_2843 0e958b8d47554f9720d6a9a3250fb0b8 342 SUPERFAMILY SSF47240 15 336 1.98E-91 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_2843 0e958b8d47554f9720d6a9a3250fb0b8 342 PIRSF PIRSF000355 1 341 3.6E-127 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_2843 0e958b8d47554f9720d6a9a3250fb0b8 342 Gene3D G3DSA:1.10.620.20 4 313 1.9E-93 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 NPD12_2843 0e958b8d47554f9720d6a9a3250fb0b8 342 Pfam PF00268 Ribonucleotide reductase, small chain 28 300 5.4E-80 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 NPD12_1123 c36e3acf5fbbf480193663423be5ede0 223 SUPERFAMILY SSF53790 12 209 5.09E-39 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 NPD12_1123 c36e3acf5fbbf480193663423be5ede0 223 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 15 207 4.3E-61 T 12-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 NPD12_1123 c36e3acf5fbbf480193663423be5ede0 223 Gene3D G3DSA:3.40.1010.10 10 110 1.1E-21 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 NPD12_1123 c36e3acf5fbbf480193663423be5ede0 223 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 12 195 9.1E-26 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 NPD12_2516 73d33eb092bb063523e13a7287a3a7de 298 Pfam PF01925 Sulfite exporter TauE/SafE 4 147 5.5E-12 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_2516 73d33eb092bb063523e13a7287a3a7de 298 Pfam PF01925 Sulfite exporter TauE/SafE 173 284 2.3E-8 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 232 6.7E-73 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 Pfam PF01259 SAICAR synthetase 7 231 3.0E-67 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 32.481 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 SUPERFAMILY SSF56104 3 232 2.91E-81 T 12-10-2018 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 Gene3D G3DSA:3.30.200.20 7 231 2.6E-95 T 12-10-2018 NPD12_2931 821960115f8c3862e12eb033c09bc534 234 Gene3D G3DSA:3.30.470.20 85 220 2.6E-95 T 12-10-2018 NPD12_820 a11d935848c8f270f47127c85be29eb2 396 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 389 1.4E-85 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 NPD12_820 a11d935848c8f270f47127c85be29eb2 396 SUPERFAMILY SSF144010 6 395 7.45E-49 T 12-10-2018 NPD12_820 a11d935848c8f270f47127c85be29eb2 396 Gene3D G3DSA:3.30.1330.100 7 116 3.2E-6 T 12-10-2018 NPD12_625 468ae0252144a61034342db1c4424af8 233 Gene3D G3DSA:3.40.50.300 1 233 2.0E-56 T 12-10-2018 NPD12_625 468ae0252144a61034342db1c4424af8 233 SUPERFAMILY SSF52540 3 227 8.84E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_625 468ae0252144a61034342db1c4424af8 233 SMART SM00382 26 212 8.9E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_625 468ae0252144a61034342db1c4424af8 233 Pfam PF00005 ABC transporter 17 161 9.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_625 468ae0252144a61034342db1c4424af8 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1821 279312e49d2e6417cc976cfd65a36e3a 418 Pfam PF04143 Sulphur transport 46 406 8.2E-77 T 12-10-2018 IPR007272 Sulphur transport domain NPD12_3356 f036d0228713777d9556b85f9b60682b 361 Gene3D G3DSA:1.20.1270.370 2 200 8.4E-33 T 12-10-2018 NPD12_3356 f036d0228713777d9556b85f9b60682b 361 Gene3D G3DSA:3.40.50.11900 218 361 5.3E-39 T 12-10-2018 NPD12_3356 f036d0228713777d9556b85f9b60682b 361 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 17 361 4.4E-78 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_3356 f036d0228713777d9556b85f9b60682b 361 Gene3D G3DSA:3.40.50.11890 9 135 8.4E-33 T 12-10-2018 NPD12_1710 aefee9fb82b713c86938d8ee8e9b7b14 370 Pfam PF01098 Cell cycle protein 15 367 5.7E-109 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1710 aefee9fb82b713c86938d8ee8e9b7b14 370 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 12 365 5.2E-117 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_1710 aefee9fb82b713c86938d8ee8e9b7b14 370 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 12 364 7.3E-153 T 12-10-2018 IPR013438 Sporulation stage V, protein E NPD12_1948 7d7825b534a453e31119f8547e7ae784 311 Gene3D G3DSA:3.40.50.300 8 290 2.1E-107 T 12-10-2018 NPD12_1948 7d7825b534a453e31119f8547e7ae784 311 Gene3D G3DSA:1.10.20.140 111 183 2.1E-107 T 12-10-2018 NPD12_1948 7d7825b534a453e31119f8547e7ae784 311 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 5 292 2.3E-103 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 NPD12_1948 7d7825b534a453e31119f8547e7ae784 311 SUPERFAMILY SSF52540 5 147 2.21E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1948 7d7825b534a453e31119f8547e7ae784 311 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 302 30.944 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 NPD12_1948 7d7825b534a453e31119f8547e7ae784 311 SUPERFAMILY SSF52540 5 311 1.74E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1948 7d7825b534a453e31119f8547e7ae784 311 Pfam PF01715 IPP transferase 37 285 1.7E-81 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 NPD12_613 15b631ca34ca9b4fb89c0faea9309374 211 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 105 1.0E-28 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 NPD12_613 15b631ca34ca9b4fb89c0faea9309374 211 SUPERFAMILY SSF161098 11 201 2.49E-44 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_613 15b631ca34ca9b4fb89c0faea9309374 211 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 2.9E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_613 15b631ca34ca9b4fb89c0faea9309374 211 Gene3D G3DSA:1.10.3720.10 3 210 1.7E-54 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1718 e2fbc08c3d3f3148d351ca333f83dcd4 256 Gene3D G3DSA:3.30.70.330 80 165 1.5E-22 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily NPD12_1718 e2fbc08c3d3f3148d351ca333f83dcd4 256 SUPERFAMILY SSF55174 46 250 4.56E-19 T 12-10-2018 NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 176 200 - T 12-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 SUPERFAMILY SSF48179 178 275 8.5E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 176 2.6E-60 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 SUPERFAMILY SSF51735 2 176 1.7E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 Gene3D G3DSA:1.10.1040.10 182 276 4.4E-34 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 179 275 2.6E-34 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 Gene3D G3DSA:3.40.50.720 1 181 1.2E-63 T 12-10-2018 NPD12_3312 c455c621321aa5cb8f791f47347d6865 276 PIRSF PIRSF000105 1 276 3.4E-88 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 NPD12_2519 fb143a7f07617d92e658b94c5d2b24fe 358 Gene3D G3DSA:2.40.420.10 16 97 3.5E-15 T 12-10-2018 NPD12_2519 fb143a7f07617d92e658b94c5d2b24fe 358 Gene3D G3DSA:3.40.50.10690 113 358 7.9E-86 T 12-10-2018 NPD12_1136 d8b7f013de9a033e47cb744aef2148e6 255 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 252 4.5E-56 T 12-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 NPD12_1136 d8b7f013de9a033e47cb744aef2148e6 255 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 250 1.1E-64 T 12-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 NPD12_432 4e37b8455b880680a8e6c465b482125d 225 SMART SM00862 147 223 4.5E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_432 4e37b8455b880680a8e6c465b482125d 225 Gene3D G3DSA:3.40.50.2300 1 124 2.1E-36 T 12-10-2018 NPD12_432 4e37b8455b880680a8e6c465b482125d 225 Pfam PF00072 Response regulator receiver domain 5 114 1.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_432 4e37b8455b880680a8e6c465b482125d 225 SUPERFAMILY SSF52172 4 177 7.03E-40 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_432 4e37b8455b880680a8e6c465b482125d 225 SMART SM00448 3 113 9.4E-40 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_432 4e37b8455b880680a8e6c465b482125d 225 Gene3D G3DSA:1.10.10.10 125 225 1.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_432 4e37b8455b880680a8e6c465b482125d 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 3.6E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1428 572c07ec568f6eb68e0abfa4d27c21ec 177 SUPERFAMILY SSF47413 1 67 3.94E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1428 572c07ec568f6eb68e0abfa4d27c21ec 177 SMART SM00530 6 61 2.1E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1428 572c07ec568f6eb68e0abfa4d27c21ec 177 Pfam PF07883 Cupin domain 118 169 4.1E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel NPD12_1428 572c07ec568f6eb68e0abfa4d27c21ec 177 Gene3D G3DSA:2.60.120.10 88 176 4.7E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1428 572c07ec568f6eb68e0abfa4d27c21ec 177 Pfam PF01381 Helix-turn-helix 7 60 3.5E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1428 572c07ec568f6eb68e0abfa4d27c21ec 177 SUPERFAMILY SSF51182 54 174 7.79E-17 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_1428 572c07ec568f6eb68e0abfa4d27c21ec 177 Gene3D G3DSA:1.10.260.40 1 87 4.7E-18 T 12-10-2018 NPD12_231 1150011e31f71e14e560fff17a8cbfaf 144 SUPERFAMILY SSF46785 7 140 6.93E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_231 1150011e31f71e14e560fff17a8cbfaf 144 Gene3D G3DSA:1.10.10.10 1 142 8.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_231 1150011e31f71e14e560fff17a8cbfaf 144 Pfam PF01047 MarR family 33 90 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_231 1150011e31f71e14e560fff17a8cbfaf 144 SMART SM00347 26 126 3.0E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1648 fe44658913b103d757aa023c2b4d2b50 183 SUPERFAMILY SSF55469 1 182 4.84E-46 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_1648 fe44658913b103d757aa023c2b4d2b50 183 Pfam PF00881 Nitroreductase family 8 163 3.3E-34 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_1648 fe44658913b103d757aa023c2b4d2b50 183 Gene3D G3DSA:3.40.109.10 1 181 1.2E-50 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_2514 55252598a30f4738ef969a0ef7dc7370 704 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 256 595 3.1E-20 T 12-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 NPD12_2514 55252598a30f4738ef969a0ef7dc7370 704 TIGRFAM TIGR04480 D_pro_red_PrdA: D-proline reductase (dithiol), PrdA proprotein 103 674 2.4E-265 T 12-10-2018 IPR031002 D-proline reductase, PrdA proprotein GO:0050002|GO:0055114 KEGG: 00330+1.21.4.1 NPD12_759 e7ce6fb5f58c1e50a96862bbea2aa9ea 450 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 333 415 1.6E-14 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_759 e7ce6fb5f58c1e50a96862bbea2aa9ea 450 Pfam PF13353 4Fe-4S single cluster domain 100 218 2.0E-12 T 12-10-2018 NPD12_759 e7ce6fb5f58c1e50a96862bbea2aa9ea 450 TIGRFAM TIGR04334 rSAM_Clo7bot: radical SAM/SPASM domain Clo7bot peptide maturase 2 440 4.6E-258 T 12-10-2018 IPR027622 Radical SAM/SPASM domain-containing Clo7bot peptide maturase NPD12_759 e7ce6fb5f58c1e50a96862bbea2aa9ea 450 Gene3D G3DSA:3.20.20.70 90 439 2.4E-58 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_759 e7ce6fb5f58c1e50a96862bbea2aa9ea 450 SUPERFAMILY SSF102114 93 407 8.63E-45 T 12-10-2018 NPD12_759 e7ce6fb5f58c1e50a96862bbea2aa9ea 450 Pfam PF04055 Radical SAM superfamily 97 262 2.7E-20 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2155 9add919be0bf337c740bb62f8fb4b501 286 PIRSF PIRSF001359 3 286 7.1E-117 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 NPD12_2155 9add919be0bf337c740bb62f8fb4b501 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 285 5.7E-106 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 NPD12_2155 9add919be0bf337c740bb62f8fb4b501 286 Gene3D G3DSA:3.20.20.70 3 286 1.6E-112 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2155 9add919be0bf337c740bb62f8fb4b501 286 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 NPD12_2155 9add919be0bf337c740bb62f8fb4b501 286 SUPERFAMILY SSF51569 4 285 1.76E-104 T 12-10-2018 NPD12_2155 9add919be0bf337c740bb62f8fb4b501 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 6 285 4.1E-105 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 NPD12_2155 9add919be0bf337c740bb62f8fb4b501 286 TIGRFAM TIGR01858 tag_bisphos_ald: class II aldolase, tagatose bisphosphate family 4 285 2.0E-149 T 12-10-2018 IPR011288 D-tagatose-bisphosphate aldolase, class II, subunit KbaY/GatY GO:0005975|GO:0008270|GO:0009025 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 NPD12_245 921c2bd09038c2a46e251d37b94ac00c 63 Gene3D G3DSA:3.30.70.20 1 61 3.2E-15 T 12-10-2018 NPD12_245 921c2bd09038c2a46e251d37b94ac00c 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.3E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 NPD12_245 921c2bd09038c2a46e251d37b94ac00c 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.3E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 NPD12_245 921c2bd09038c2a46e251d37b94ac00c 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.3E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 NPD12_245 921c2bd09038c2a46e251d37b94ac00c 63 SUPERFAMILY SSF54862 1 60 1.92E-11 T 12-10-2018 NPD12_245 921c2bd09038c2a46e251d37b94ac00c 63 Pfam PF13459 4Fe-4S single cluster domain 3 60 7.4E-11 T 12-10-2018 NPD12_1325 0f7344fed5190574bfbc7966d1919dee 166 SUPERFAMILY SSF50475 8 164 2.7E-18 T 12-10-2018 NPD12_1325 0f7344fed5190574bfbc7966d1919dee 166 Gene3D G3DSA:2.30.110.10 16 165 2.1E-27 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_1325 0f7344fed5190574bfbc7966d1919dee 166 Pfam PF01613 Flavin reductase like domain 32 163 7.3E-5 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Gene3D G3DSA:1.10.150.20 75 136 7.8E-12 T 12-10-2018 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Pfam PF13604 AAA domain 320 505 9.9E-48 T 12-10-2018 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 SUPERFAMILY SSF47781 78 156 2.22E-11 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Gene3D G3DSA:3.40.50.300 481 722 2.4E-146 T 12-10-2018 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Pfam PF14520 Helix-hairpin-helix domain 88 133 2.0E-8 T 12-10-2018 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Gene3D G3DSA:3.40.50.300 306 727 2.4E-146 T 12-10-2018 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Pfam PF13538 UvrD-like helicase C-terminal domain 659 706 6.2E-18 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Gene3D G3DSA:1.10.10.2220 179 273 1.8E-18 T 12-10-2018 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Gene3D G3DSA:2.30.30.940 571 659 2.4E-146 T 12-10-2018 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 SMART SM00278 180 199 320.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 SMART SM00278 81 102 920.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 SMART SM00278 116 135 2.1 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 1 735 28.712 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 Pfam PF14490 Helix-hairpin-helix containing domain 138 228 9.6E-33 T 12-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 SUPERFAMILY SSF52540 312 711 1.34E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 4 728 3.5E-211 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 NPD12_327 e21cfba74c07465668d2dcc37e109bf1 744 SMART SM00382 332 451 4.7E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2810 167ba5ef3e54ddeb91bc5add6a33d2c0 297 Pfam PF01522 Polysaccharide deacetylase 88 195 4.3E-28 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 NPD12_2810 167ba5ef3e54ddeb91bc5add6a33d2c0 297 Gene3D G3DSA:3.20.20.370 48 293 3.1E-60 T 12-10-2018 NPD12_2810 167ba5ef3e54ddeb91bc5add6a33d2c0 297 SUPERFAMILY SSF88713 90 284 2.2E-46 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_2661 a87b96e284e1d6e7a8872054f5b8acb0 224 TIGRFAM TIGR04283 glyco_like_mftF: transferase 2, rSAM/selenodomain-associated 2 220 1.4E-70 T 12-10-2018 IPR026461 Transferase 2, rSAM/selenodomain-associated NPD12_2661 a87b96e284e1d6e7a8872054f5b8acb0 224 SUPERFAMILY SSF53448 1 206 2.33E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2661 a87b96e284e1d6e7a8872054f5b8acb0 224 Gene3D G3DSA:3.90.550.10 1 187 3.5E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2661 a87b96e284e1d6e7a8872054f5b8acb0 224 Pfam PF00535 Glycosyl transferase family 2 3 120 3.3E-18 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_1154 62d218d5ed679bba2c8eddaf02c41b7e 355 Gene3D G3DSA:1.10.3470.10 11 353 2.7E-99 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1154 62d218d5ed679bba2c8eddaf02c41b7e 355 SUPERFAMILY SSF81345 7 347 6.28E-83 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1154 62d218d5ed679bba2c8eddaf02c41b7e 355 Pfam PF01032 FecCD transport family 25 347 3.4E-98 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_1268 95db3ee77371005663a053f1ac1da1b5 376 Pfam PF00155 Aminotransferase class I and II 48 359 2.7E-45 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1268 95db3ee77371005663a053f1ac1da1b5 376 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 220 233 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 NPD12_1268 95db3ee77371005663a053f1ac1da1b5 376 Gene3D G3DSA:3.40.640.10 57 273 5.8E-119 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1268 95db3ee77371005663a053f1ac1da1b5 376 SUPERFAMILY SSF53383 17 370 1.73E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1268 95db3ee77371005663a053f1ac1da1b5 376 Gene3D G3DSA:3.90.1150.10 15 363 5.8E-119 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_828 8bd45db8d4331e2c8ec98e2c221d95cb 462 SUPERFAMILY SSF55874 22 193 1.52E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_828 8bd45db8d4331e2c8ec98e2c221d95cb 462 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 95 3.9E-7 T 12-10-2018 NPD12_828 8bd45db8d4331e2c8ec98e2c221d95cb 462 Gene3D G3DSA:3.30.565.10 21 179 1.1E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1367 5020a6e34a74df99f3b24643f922e6fd 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 219 3.7E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1367 5020a6e34a74df99f3b24643f922e6fd 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 113 2.1E-27 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 NPD12_1367 5020a6e34a74df99f3b24643f922e6fd 222 Gene3D G3DSA:1.10.3720.10 4 221 2.2E-56 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1367 5020a6e34a74df99f3b24643f922e6fd 222 SUPERFAMILY SSF161098 16 204 6.93E-47 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_71 4b0ca80675c6b557c2669cd302299b35 308 Gene3D G3DSA:3.20.20.70 3 307 2.5E-111 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_71 4b0ca80675c6b557c2669cd302299b35 308 Pfam PF03060 Nitronate monooxygenase 5 299 6.3E-77 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 NPD12_71 4b0ca80675c6b557c2669cd302299b35 308 SUPERFAMILY SSF51412 8 304 5.04E-80 T 12-10-2018 NPD12_71 4b0ca80675c6b557c2669cd302299b35 308 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 6 302 1.5E-154 T 12-10-2018 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 Gene3D G3DSA:3.30.1340.20 65 172 5.9E-38 T 12-10-2018 IPR035922 3H domain superfamily NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 Gene3D G3DSA:1.10.10.10 1 61 1.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 SUPERFAMILY SSF46785 1 61 1.56E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 Pfam PF08279 HTH domain 6 58 1.5E-14 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 Pfam PF02829 3H domain 72 168 5.7E-36 T 12-10-2018 IPR004173 3H domain GO:0036094 NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 91 169 8.0E-25 T 12-10-2018 IPR004173 3H domain GO:0036094 NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 PIRSF PIRSF037847 1 171 1.3E-70 T 12-10-2018 IPR026043 Transcription repressor NadR NPD12_141 f5a1069de85305bb28df1f2b0efd1a02 173 SUPERFAMILY SSF75500 68 170 4.58E-34 T 12-10-2018 IPR035922 3H domain superfamily NPD12_1205 950d64c88dae60cc249e4eb894f365da 192 Gene3D G3DSA:3.50.30.50 2 191 2.4E-29 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_1205 950d64c88dae60cc249e4eb894f365da 192 Pfam PF04199 Putative cyclase 3 130 9.0E-13 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_1205 950d64c88dae60cc249e4eb894f365da 192 SUPERFAMILY SSF102198 26 191 2.09E-33 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_1570 f29b4478ce2fb3abea7a682ec778b1f1 154 Pfam PF10779 Haemolysin XhlA 13 76 1.0E-21 T 12-10-2018 IPR019715 Haemolysin XhlA NPD12_1443 e9b2506121b34871517f83f1309f9321 313 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 9 306 2.1E-107 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 295 1.3E-44 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 1.4E-65 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 SUPERFAMILY SSF51905 3 305 9.58E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1443 e9b2506121b34871517f83f1309f9321 313 Gene3D G3DSA:3.50.50.60 124 246 4.0E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.0E-36 T 12-10-2018 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.0E-36 T 12-10-2018 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.0E-36 T 12-10-2018 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.0E-36 T 12-10-2018 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.0E-36 T 12-10-2018 NPD12_1443 e9b2506121b34871517f83f1309f9321 313 Gene3D G3DSA:3.50.50.60 11 305 4.0E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 298 7.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 7.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 7.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 7.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 SMART SM00387 229 344 1.6E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 Gene3D G3DSA:3.30.565.10 190 345 5.3E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 SUPERFAMILY SSF55874 188 340 1.31E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_441 f17e5a8e1f6f1be1c0103f8f6138c483 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 230 340 3.1E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_812 6575bb082596128f199de2d5a22c919d 159 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 12 157 1.6E-17 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related NPD12_812 6575bb082596128f199de2d5a22c919d 159 SUPERFAMILY SSF50475 1 158 8.45E-42 T 12-10-2018 NPD12_812 6575bb082596128f199de2d5a22c919d 159 Gene3D G3DSA:2.30.110.10 1 158 4.2E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 SMART SM00028 123 156 4.6E-9 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 SMART SM00028 7 40 20.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 Gene3D G3DSA:1.25.40.10 66 174 8.3E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 Gene3D G3DSA:1.25.40.10 2 65 3.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 Pfam PF13174 Tetratricopeptide repeat 373 403 0.12 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 Pfam PF00515 Tetratricopeptide repeat 124 156 1.1E-10 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 SUPERFAMILY SSF48452 9 361 3.6E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 SUPERFAMILY SSF48452 78 169 3.29E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3594 7b21a02b6ebc050329b3da24b63ffb8d 417 Gene3D G3DSA:1.25.40.10 298 416 7.7E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1016 0f9c0500b827564dee049bd732b4f68a 151 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 131 7.6E-46 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 NPD12_1016 0f9c0500b827564dee049bd732b4f68a 151 Gene3D G3DSA:3.30.70.560 1 151 1.5E-61 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 NPD12_1016 0f9c0500b827564dee049bd732b4f68a 151 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 87 98 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 NPD12_1016 0f9c0500b827564dee049bd732b4f68a 151 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 131 1.1E-39 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 NPD12_1016 0f9c0500b827564dee049bd732b4f68a 151 SUPERFAMILY SSF55083 1 150 6.8E-54 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 NPD12_1927 e563379f72467571729560f220e7b9ee 526 Pfam PF12848 ABC transporter 224 307 9.9E-21 T 12-10-2018 IPR032781 ABC-transporter extension domain NPD12_1927 e563379f72467571729560f220e7b9ee 526 SUPERFAMILY SSF52540 296 512 1.5E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1927 e563379f72467571729560f220e7b9ee 526 Pfam PF00005 ABC transporter 18 184 6.6E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1927 e563379f72467571729560f220e7b9ee 526 Pfam PF00005 ABC transporter 335 466 1.3E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1927 e563379f72467571729560f220e7b9ee 526 Gene3D G3DSA:3.40.50.300 1 279 9.5E-61 T 12-10-2018 NPD12_1927 e563379f72467571729560f220e7b9ee 526 SUPERFAMILY SSF52540 2 254 5.34E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1927 e563379f72467571729560f220e7b9ee 526 SMART SM00382 26 228 2.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1927 e563379f72467571729560f220e7b9ee 526 Gene3D G3DSA:3.40.50.300 282 526 9.8E-38 T 12-10-2018 NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 PIRSF PIRSF002825 1 346 2.6E-102 T 12-10-2018 IPR026045 Ferric binding protein NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 Gene3D G3DSA:3.40.190.10 50 314 6.3E-86 T 12-10-2018 NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 SUPERFAMILY SSF53850 51 342 8.7E-64 T 12-10-2018 NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 Gene3D G3DSA:3.40.190.10 142 325 6.3E-86 T 12-10-2018 NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 Pfam PF13343 Bacterial extracellular solute-binding protein 89 299 3.1E-39 T 12-10-2018 NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 62 83 9.5E-7 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 159 173 9.5E-7 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_1341 d4f5c4495a5fad5d7befa6ac114cf6a2 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 9.5E-7 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_3095 cf665e73f857d0da3edda93cb313bb9f 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 104 27.886 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3095 cf665e73f857d0da3edda93cb313bb9f 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 102 5.6E-43 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3095 cf665e73f857d0da3edda93cb313bb9f 104 SUPERFAMILY SSF141091 1 103 2.35E-39 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3095 cf665e73f857d0da3edda93cb313bb9f 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3095 cf665e73f857d0da3edda93cb313bb9f 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 103 7.6E-39 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3156 7d633a82ef704557a671cff72954da17 483 SUPERFAMILY SSF52266 50 313 2.0E-9 T 12-10-2018 NPD12_908 98303289c69a2f0dee6ddaa06d5baf88 91 Pfam PF08765 Mor transcription activator family 14 88 5.4E-6 T 12-10-2018 IPR014875 Mor transcription activator NPD12_908 98303289c69a2f0dee6ddaa06d5baf88 91 SUPERFAMILY SSF46689 1 89 2.24E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 Pfam PF00082 Subtilase family 157 466 6.6E-46 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 SUPERFAMILY SSF52743 136 477 1.06E-67 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 205 218 1.6E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 156 175 1.6E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 417 433 1.6E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 161 172 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 418 428 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 209 219 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site NPD12_3463 e1e9a1e9d3b32fe966489c3dc0dca3e2 480 Gene3D G3DSA:3.40.50.200 121 480 8.9E-83 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_268 2f33b6affe078e34d73fc411b63888ba 375 SUPERFAMILY SSF53756 9 372 1.19E-78 T 12-10-2018 NPD12_268 2f33b6affe078e34d73fc411b63888ba 375 Pfam PF00534 Glycosyl transferases group 1 194 349 2.4E-37 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_268 2f33b6affe078e34d73fc411b63888ba 375 Gene3D G3DSA:3.40.50.2000 181 372 1.5E-47 T 12-10-2018 NPD12_268 2f33b6affe078e34d73fc411b63888ba 375 Gene3D G3DSA:3.40.50.2000 1 180 3.8E-12 T 12-10-2018 NPD12_268 2f33b6affe078e34d73fc411b63888ba 375 Pfam PF13439 Glycosyltransferase Family 4 17 168 9.2E-10 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_218 80028ece5e6c5a20c87979c5127e084a 246 SUPERFAMILY SSF53335 8 209 2.27E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_218 80028ece5e6c5a20c87979c5127e084a 246 Pfam PF05175 Methyltransferase small domain 34 173 4.7E-10 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 NPD12_218 80028ece5e6c5a20c87979c5127e084a 246 Gene3D G3DSA:3.40.50.150 9 245 3.7E-62 T 12-10-2018 NPD12_2441 c21dcf0d091ecb0f8371b58cbab45d3b 269 SUPERFAMILY SSF52540 93 251 5.4E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2441 c21dcf0d091ecb0f8371b58cbab45d3b 269 Gene3D G3DSA:3.40.50.300 72 258 1.3E-36 T 12-10-2018 NPD12_2441 c21dcf0d091ecb0f8371b58cbab45d3b 269 Pfam PF01695 IstB-like ATP binding protein 124 235 1.0E-16 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 NPD12_2 a7a9b46ce17f3d46a44dacc4264cfcb8 96 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 15 96 2.0E-21 T 12-10-2018 IPR012504 Sporulation protein YabP NPD12_2 a7a9b46ce17f3d46a44dacc4264cfcb8 96 PIRSF PIRSF011576 1 96 2.6E-17 T 12-10-2018 IPR012504 Sporulation protein YabP NPD12_2 a7a9b46ce17f3d46a44dacc4264cfcb8 96 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 13 96 2.8E-34 T 12-10-2018 IPR012504 Sporulation protein YabP NPD12_2 a7a9b46ce17f3d46a44dacc4264cfcb8 96 Pfam PF07873 YabP family 14 78 2.6E-19 T 12-10-2018 IPR022476 Sporulation protein YabP/YqfC NPD12_2 a7a9b46ce17f3d46a44dacc4264cfcb8 96 Gene3D G3DSA:2.60.40.2000 21 78 1.3E-20 T 12-10-2018 IPR038705 YabP superfamily NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 SUPERFAMILY SSF52540 151 394 1.6E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 SMART SM00382 172 324 8.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 SUPERFAMILY SSF55785 28 129 1.44E-5 T 12-10-2018 IPR035965 PAS domain superfamily NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 Gene3D G3DSA:1.10.8.60 325 403 1.3E-20 T 12-10-2018 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 SUPERFAMILY SSF46689 366 460 7.62E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 Pfam PF02954 Bacterial regulatory protein, Fis family 417 457 1.4E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 239 254 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 Gene3D G3DSA:3.30.450.20 37 141 3.2E-10 T 12-10-2018 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 Gene3D G3DSA:1.10.10.60 416 462 2.0E-14 T 12-10-2018 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 Pfam PF00158 Sigma-54 interaction domain 152 319 8.1E-69 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 Gene3D G3DSA:3.40.50.300 142 324 9.7E-63 T 12-10-2018 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 423 440 7.9E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_773 e3dc184bd038ca0e42d5ef88d3da53bd 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 440 460 7.9E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 NPD12_844 6f0abb20d7c9dc46e088dffa665cb57f 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 267 1.5E-26 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 NPD12_2111 6ad9dd127993b89ccfbf5da1f1f1ed25 223 Gene3D G3DSA:1.10.3720.10 2 223 1.2E-30 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2111 6ad9dd127993b89ccfbf5da1f1f1ed25 223 SUPERFAMILY SSF161098 13 217 4.45E-33 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2111 6ad9dd127993b89ccfbf5da1f1f1ed25 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 216 3.2E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_2646 57fe8c413c548d97b0b62f42dfe0e767 158 Gene3D G3DSA:3.30.1490.410 31 158 7.6E-46 T 12-10-2018 NPD12_2646 57fe8c413c548d97b0b62f42dfe0e767 158 Pfam PF16224 DOmain of unknown function (DUF4883) 34 152 7.0E-46 T 12-10-2018 IPR032619 Protein of unknown function DUF4883 NPD12_1382 3976665fffddd7662494525278472104 491 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 12 461 2.4E-118 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 NPD12_1382 3976665fffddd7662494525278472104 491 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 10 477 44.921 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 Gene3D G3DSA:1.20.1330.10 176 227 8.8E-12 T 12-10-2018 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 Gene3D G3DSA:1.20.1330.10 42 169 6.5E-48 T 12-10-2018 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 SUPERFAMILY SSF64518 3 261 1.57E-56 T 12-10-2018 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 Pfam PF00700 Bacterial flagellin C-terminal helical region 183 262 2.5E-7 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 Pfam PF00669 Bacterial flagellin N-terminal helical region 14 137 8.8E-33 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 PRINTS PR00207 Flagellin signature 73 92 5.0E-16 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 PRINTS PR00207 Flagellin signature 108 131 5.0E-16 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 PRINTS PR00207 Flagellin signature 34 51 5.0E-16 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 Gene3D G3DSA:1.20.58.1830 11 30 6.5E-48 T 12-10-2018 NPD12_2743 b0227e0c6d9c9b69bc09b04f3a1dd708 272 Gene3D G3DSA:1.20.58.1830 233 254 8.8E-12 T 12-10-2018 NPD12_3674 7296ff706a0590634d3fc040b0a6795e 175 PIRSF PIRSF015034 1 175 3.5E-62 T 12-10-2018 IPR025542 YacH protein NPD12_3674 7296ff706a0590634d3fc040b0a6795e 175 SUPERFAMILY SSF46600 137 170 3.01E-6 T 12-10-2018 IPR036876 UVR domain superfamily NPD12_3674 7296ff706a0590634d3fc040b0a6795e 175 Pfam PF02151 UvrB/uvrC motif 137 170 3.7E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 NPD12_2092 4b37ee6bcbaa3df06e7a89e175b3261c 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 4.7E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2092 4b37ee6bcbaa3df06e7a89e175b3261c 229 Gene3D G3DSA:3.40.50.2300 3 128 2.6E-38 T 12-10-2018 NPD12_2092 4b37ee6bcbaa3df06e7a89e175b3261c 229 Gene3D G3DSA:1.10.10.10 129 228 8.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2092 4b37ee6bcbaa3df06e7a89e175b3261c 229 SUPERFAMILY SSF52172 4 180 7.68E-40 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2092 4b37ee6bcbaa3df06e7a89e175b3261c 229 Pfam PF00072 Response regulator receiver domain 5 113 2.2E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2092 4b37ee6bcbaa3df06e7a89e175b3261c 229 SMART SM00448 3 112 4.1E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2092 4b37ee6bcbaa3df06e7a89e175b3261c 229 SMART SM00862 149 224 1.7E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_3301 8b77bc70ebeee1f58a06f0dc563e6d29 358 Gene3D G3DSA:2.40.420.10 16 97 3.6E-16 T 12-10-2018 NPD12_3301 8b77bc70ebeee1f58a06f0dc563e6d29 358 Gene3D G3DSA:3.40.50.10690 113 358 1.6E-85 T 12-10-2018 NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 SUPERFAMILY SSF48008 95 228 1.07E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.1E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 SUPERFAMILY SSF46785 1 76 3.91E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 Pfam PF07729 FCD domain 98 222 3.4E-21 T 12-10-2018 IPR011711 GntR, C-terminal NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 SMART SM00895 98 223 2.2E-17 T 12-10-2018 IPR011711 GntR, C-terminal NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.2E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.2E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 Gene3D G3DSA:1.20.120.530 96 233 4.9E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 SMART SM00345 14 73 4.8E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1763 cae047e41eaf23c32c70ae545f47a14a 236 Gene3D G3DSA:1.10.10.10 1 73 3.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2812 da33f48a9a8180322ca87736243bd36f 326 Gene3D G3DSA:3.40.50.720 3 251 1.9E-129 T 12-10-2018 NPD12_2812 da33f48a9a8180322ca87736243bd36f 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 251 4.1E-61 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 NPD12_2812 da33f48a9a8180322ca87736243bd36f 326 Gene3D G3DSA:3.90.25.10 172 304 1.9E-129 T 12-10-2018 NPD12_2812 da33f48a9a8180322ca87736243bd36f 326 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 325 1.0E-137 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 NPD12_2812 da33f48a9a8180322ca87736243bd36f 326 SUPERFAMILY SSF51735 3 325 1.32E-97 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2883 304b01976948f8e9c7633e361c4bb813 217 SUPERFAMILY SSF100950 2 216 4.47E-68 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_2883 304b01976948f8e9c7633e361c4bb813 217 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 207 2.7E-85 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 NPD12_2883 304b01976948f8e9c7633e361c4bb813 217 SMART SM00882 5 201 9.8E-58 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 NPD12_2883 304b01976948f8e9c7633e361c4bb813 217 Gene3D G3DSA:3.40.1080.10 1 213 3.1E-89 T 12-10-2018 NPD12_2883 304b01976948f8e9c7633e361c4bb813 217 Pfam PF01144 Coenzyme A transferase 5 200 2.1E-34 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 NPD12_3783 fa524be460c1b03f57e47a4b7a13f696 866 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 263 574 2.0E-55 T 12-10-2018 IPR010090 Phage tail tape measure protein NPD12_3783 fa524be460c1b03f57e47a4b7a13f696 866 Pfam PF10145 Phage-related minor tail protein 299 491 9.5E-39 T 12-10-2018 IPR010090 Phage tail tape measure protein NPD12_1917 b1d6100befd4538bc1e5275414cbfd84 301 SUPERFAMILY SSF53613 1 299 1.31E-62 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1917 b1d6100befd4538bc1e5275414cbfd84 301 Gene3D G3DSA:3.40.1190.20 1 301 4.0E-96 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1917 b1d6100befd4538bc1e5275414cbfd84 301 PIRSF PIRSF000535 1 301 8.5E-76 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 NPD12_1917 b1d6100befd4538bc1e5275414cbfd84 301 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 5.8E-109 T 12-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 NPD12_1917 b1d6100befd4538bc1e5275414cbfd84 301 Pfam PF00294 pfkB family carbohydrate kinase 13 289 6.3E-47 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB NPD12_1917 b1d6100befd4538bc1e5275414cbfd84 301 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 2.0E-106 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 NPD12_1917 b1d6100befd4538bc1e5275414cbfd84 301 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 245 258 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 NPD12_589 1bae89bb80c7fb967df08feacc543323 332 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 224 243 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 NPD12_589 1bae89bb80c7fb967df08feacc543323 332 SUPERFAMILY SSF53659 1 332 9.98E-134 T 12-10-2018 NPD12_589 1bae89bb80c7fb967df08feacc543323 332 Gene3D G3DSA:3.40.718.10 1 332 1.1E-152 T 12-10-2018 NPD12_589 1bae89bb80c7fb967df08feacc543323 332 SMART SM01329 4 328 1.2E-194 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 NPD12_589 1bae89bb80c7fb967df08feacc543323 332 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 328 4.3E-115 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 NPD12_1646 5ba3fc9b51ccd84bca0af2cd84cb58de 366 Pfam PF12698 ABC-2 family transporter protein 21 355 1.2E-28 T 12-10-2018 NPD12_1646 5ba3fc9b51ccd84bca0af2cd84cb58de 366 Gene3D G3DSA:3.40.1710.10 44 179 8.9E-6 T 12-10-2018 NPD12_2367 e0e649cbfa99058e06f11ed1166c2f36 356 SUPERFAMILY SSF51726 6 348 6.1E-49 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_2367 e0e649cbfa99058e06f11ed1166c2f36 356 Gene3D G3DSA:3.20.20.210 1 345 1.6E-70 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_2367 e0e649cbfa99058e06f11ed1166c2f36 356 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 345 2.8E-68 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 NPD12_3228 1e2f198bea26125310306e507be3dab2 300 SUPERFAMILY SSF53659 4 297 2.11E-59 T 12-10-2018 NPD12_3228 1e2f198bea26125310306e507be3dab2 300 Pfam PF01515 Phosphate acetyl/butaryl transferase 76 294 9.8E-46 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_3228 1e2f198bea26125310306e507be3dab2 300 PIRSF PIRSF000428 1 300 3.7E-83 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_3228 1e2f198bea26125310306e507be3dab2 300 Gene3D G3DSA:3.40.718.10 2 299 4.8E-102 T 12-10-2018 NPD12_1391 411977300522153d4158cf48105dc732 123 Gene3D G3DSA:1.10.10.10 8 120 8.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1391 411977300522153d4158cf48105dc732 123 SMART SM00345 15 74 8.6E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1391 411977300522153d4158cf48105dc732 123 SUPERFAMILY SSF46785 4 82 3.01E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1391 411977300522153d4158cf48105dc732 123 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1915 41fada9b4db6f601f9c430958c390a8a 316 Pfam PF06207 Protein of unknown function (DUF1002) 39 258 2.9E-85 T 12-10-2018 IPR009343 Protein of unknown function DUF1002 NPD12_1439 9080a9b9c82ea06ad821eafab68c7b4f 85 Pfam PF12728 Helix-turn-helix domain 1 50 7.7E-7 T 12-10-2018 NPD12_1439 9080a9b9c82ea06ad821eafab68c7b4f 85 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 47 1.7E-7 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 2 557 48.958 T 12-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 SUPERFAMILY SSF52540 5 555 6.25E-249 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 12-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 Gene3D G3DSA:3.30.1510.10 130 248 1.2E-210 T 12-10-2018 NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 Pfam PF01268 Formate--tetrahydrofolate ligase 3 557 3.0E-274 T 12-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 Gene3D G3DSA:3.10.410.10 444 533 6.2E-37 T 12-10-2018 NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 104 114 - T 12-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 NPD12_3697 1b0f2acc8319c6dad5302f313d20adb2 557 Gene3D G3DSA:3.40.50.300 7 439 1.2E-210 T 12-10-2018 NPD12_3449 bc567591b018dfc26765315002a9fa71 152 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 124 1.7E-37 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 NPD12_3449 bc567591b018dfc26765315002a9fa71 152 Gene3D G3DSA:3.40.50.300 2 148 5.0E-40 T 12-10-2018 NPD12_3449 bc567591b018dfc26765315002a9fa71 152 SUPERFAMILY SSF52540 18 121 1.54E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3449 bc567591b018dfc26765315002a9fa71 152 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 9 127 4.7E-38 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 Gene3D G3DSA:3.40.190.10 399 606 6.4E-107 T 12-10-2018 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 256 7.6E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 Gene3D G3DSA:1.10.3720.10 7 263 9.0E-57 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 SUPERFAMILY SSF53850 294 610 4.35E-84 T 12-10-2018 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 Gene3D G3DSA:3.40.190.10 297 577 6.4E-107 T 12-10-2018 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 Pfam PF13416 Bacterial extracellular solute-binding protein 309 567 5.0E-33 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 SUPERFAMILY SSF161098 9 258 9.35E-62 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 389 405 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 414 428 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 299 315 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 558 584 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 432 451 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 513 532 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 315 336 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 342 356 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 358 371 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_738 b93f3fb51248755ee34a8c10ff8d5e50 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 469 488 2.0E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 NPD12_2146 b4b2be7cce17a4c51a7d21628b277cb7 476 SUPERFAMILY SSF116726 402 463 1.12E-12 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_2146 b4b2be7cce17a4c51a7d21628b277cb7 476 Pfam PF00999 Sodium/hydrogen exchanger family 6 380 6.0E-47 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 NPD12_2146 b4b2be7cce17a4c51a7d21628b277cb7 476 Pfam PF02080 TrkA-C domain 406 464 1.6E-13 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 NPD12_2146 b4b2be7cce17a4c51a7d21628b277cb7 476 Gene3D G3DSA:3.30.70.1450 396 475 5.6E-18 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 NPD12_2146 b4b2be7cce17a4c51a7d21628b277cb7 476 Gene3D G3DSA:1.20.1530.20 1 383 2.0E-26 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_90 afc69b505444c641947c5f14d63d83a0 269 Pfam PF03618 Kinase/pyrophosphorylase 4 260 6.9E-90 T 12-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 NPD12_90 afc69b505444c641947c5f14d63d83a0 269 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 2 265 57.413 T 12-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein NPD12_2215 b5f9a08061c821307fc3a12ba519faf4 224 Pfam PF04892 VanZ like family 63 182 1.4E-24 T 12-10-2018 IPR006976 VanZ-like NPD12_748 399ea67ec35f84fa1ee856db55ba8534 334 Pfam PF02517 CAAX protease self-immunity 182 281 1.5E-15 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_2518 bca1d08f5b49c6578572ef87a675505a 361 Gene3D G3DSA:3.40.50.10690 119 361 1.7E-86 T 12-10-2018 NPD12_2518 bca1d08f5b49c6578572ef87a675505a 361 Gene3D G3DSA:2.40.420.10 16 95 1.7E-11 T 12-10-2018 NPD12_2666 50b318e774703007e5cabdd3fa008fd6 168 Gene3D G3DSA:1.10.1760.20 2 162 1.2E-7 T 12-10-2018 NPD12_464 fdd73cdabdd58865593661c468be70bf 139 Pfam PF04138 GtrA-like protein 21 138 9.6E-25 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 NPD12_2824 daed03c834f2f269b082caae3db93f3b 171 Pfam PF04892 VanZ like family 14 135 1.3E-21 T 12-10-2018 IPR006976 VanZ-like NPD12_1374 5d89ff9cd300c6703d74ee3686eed534 239 Pfam PF00072 Response regulator receiver domain 4 115 1.7E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1374 5d89ff9cd300c6703d74ee3686eed534 239 SUPERFAMILY SSF52172 1 126 1.21E-13 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1374 5d89ff9cd300c6703d74ee3686eed534 239 SMART SM00448 2 120 1.1E-10 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1374 5d89ff9cd300c6703d74ee3686eed534 239 Pfam PF04397 LytTr DNA-binding domain 148 237 1.4E-25 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_1374 5d89ff9cd300c6703d74ee3686eed534 239 Gene3D G3DSA:2.40.50.1020 138 239 3.8E-34 T 12-10-2018 NPD12_1374 5d89ff9cd300c6703d74ee3686eed534 239 SMART SM00850 147 239 5.7E-25 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_1374 5d89ff9cd300c6703d74ee3686eed534 239 Gene3D G3DSA:3.40.50.2300 2 137 5.3E-41 T 12-10-2018 NPD12_2427 1639f6f2622af23400f49219257a0609 119 SUPERFAMILY SSF82771 19 116 1.06E-9 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_2427 1639f6f2622af23400f49219257a0609 119 Gene3D G3DSA:3.40.1440.10 18 118 2.7E-16 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 Gene3D G3DSA:1.10.1060.10 247 333 3.9E-9 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 Pfam PF13534 4Fe-4S dicluster domain 258 322 5.4E-11 T 12-10-2018 NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 PRINTS PR00069 Aldo-keto reductase signature 38 62 7.7E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 PRINTS PR00069 Aldo-keto reductase signature 127 144 7.7E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 PRINTS PR00069 Aldo-keto reductase signature 90 108 7.7E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 Gene3D G3DSA:3.20.20.100 1 237 7.5E-62 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 307 318 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 SUPERFAMILY SSF46548 253 332 1.78E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 Pfam PF00248 Aldo/keto reductase family 19 198 6.7E-35 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain NPD12_3526 0587b7e64762e7c9ce0ab83357536f81 336 SUPERFAMILY SSF51430 1 279 2.23E-61 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily NPD12_919 e75353f6803afbf8ed2408f182910289 79 ProSitePatterns PS00050 Ribosomal protein L23 signature. 48 63 - T 12-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_919 e75353f6803afbf8ed2408f182910289 79 SUPERFAMILY SSF55008 10 77 1.7E-18 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_919 e75353f6803afbf8ed2408f182910289 79 Pfam PF00403 Heavy-metal-associated domain 14 75 1.2E-12 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_919 e75353f6803afbf8ed2408f182910289 79 PRINTS PR00946 Mercury scavenger protein signature 65 79 1.5E-9 T 12-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 NPD12_919 e75353f6803afbf8ed2408f182910289 79 PRINTS PR00946 Mercury scavenger protein signature 8 19 1.5E-9 T 12-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 NPD12_919 e75353f6803afbf8ed2408f182910289 79 PRINTS PR00946 Mercury scavenger protein signature 19 35 1.5E-9 T 12-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 NPD12_919 e75353f6803afbf8ed2408f182910289 79 PRINTS PR00946 Mercury scavenger protein signature 35 50 1.5E-9 T 12-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 NPD12_919 e75353f6803afbf8ed2408f182910289 79 Gene3D G3DSA:3.30.70.100 12 79 1.3E-18 T 12-10-2018 NPD12_3041 2fe2a34bf05dc6d2dc25038c298ee208 154 Gene3D G3DSA:2.30.110.40 3 147 1.2E-52 T 12-10-2018 IPR038628 XkdM-like superfamily NPD12_3041 2fe2a34bf05dc6d2dc25038c298ee208 154 Pfam PF09393 Phage tail tube protein 4 146 5.7E-53 T 12-10-2018 IPR018989 Phage tail tube protein NPD12_3041 2fe2a34bf05dc6d2dc25038c298ee208 154 SUPERFAMILY SSF69279 7 148 2.72E-48 T 12-10-2018 NPD12_1264 d0e67981b2fba81ab7edd3e247ec3195 122 SUPERFAMILY SSF160148 47 117 1.02E-24 T 12-10-2018 IPR036593 CPE0013-like superfamily NPD12_1264 d0e67981b2fba81ab7edd3e247ec3195 122 Pfam PF07892 Protein of unknown function (DUF1667) 35 116 3.6E-33 T 12-10-2018 IPR012460 Protein of unknown function DUF1667 NPD12_1264 d0e67981b2fba81ab7edd3e247ec3195 122 Gene3D G3DSA:3.10.530.10 48 116 2.9E-22 T 12-10-2018 IPR036593 CPE0013-like superfamily NPD12_1264 d0e67981b2fba81ab7edd3e247ec3195 122 SUPERFAMILY SSF53706 6 54 4.24E-6 T 12-10-2018 NPD12_2660 698e1b082af721150e961bf52ef8dacd 233 Gene3D G3DSA:3.90.550.10 1 220 2.1E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2660 698e1b082af721150e961bf52ef8dacd 233 SUPERFAMILY SSF53448 5 202 7.59E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2660 698e1b082af721150e961bf52ef8dacd 233 TIGRFAM TIGR04282 glyco_like_cofC: transferase 1, rSAM/selenodomain-associated 4 194 3.2E-59 T 12-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated NPD12_2660 698e1b082af721150e961bf52ef8dacd 233 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 53 160 2.0E-25 T 12-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 SMART SM00278 149 168 6.0E-4 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 SMART SM00278 179 198 5.6 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 Pfam PF10531 SLBB domain 61 114 3.4E-14 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 139 198 1.9E-16 T 12-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 Gene3D G3DSA:1.10.150.310 148 202 1.4E-13 T 12-10-2018 NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 SUPERFAMILY SSF47781 130 198 6.78E-25 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 Gene3D G3DSA:3.10.560.10 39 147 1.9E-6 T 12-10-2018 NPD12_3084 b4ad5fd73f52b31c7a365ad38ceaac00 202 Pfam PF12836 Helix-hairpin-helix motif 139 197 2.3E-21 T 12-10-2018 NPD12_230 83c86ce00df8d5158fd857a980cb3a98 190 Pfam PF03167 Uracil DNA glycosylase superfamily 28 175 2.3E-44 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_230 83c86ce00df8d5158fd857a980cb3a98 190 SMART SM00986 28 175 5.6E-37 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_230 83c86ce00df8d5158fd857a980cb3a98 190 Gene3D G3DSA:3.40.470.10 2 189 6.2E-69 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_230 83c86ce00df8d5158fd857a980cb3a98 190 SUPERFAMILY SSF52141 4 183 3.04E-61 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 NPD12_230 83c86ce00df8d5158fd857a980cb3a98 190 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 14 180 1.6E-58 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 NPD12_230 83c86ce00df8d5158fd857a980cb3a98 190 SMART SM00987 28 175 5.6E-37 T 12-10-2018 NPD12_810 9a5c272b7aba21fcdb752d5c7f70aae3 157 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 12 154 2.7E-21 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related NPD12_810 9a5c272b7aba21fcdb752d5c7f70aae3 157 SUPERFAMILY SSF50475 4 156 1.68E-40 T 12-10-2018 NPD12_810 9a5c272b7aba21fcdb752d5c7f70aae3 157 Gene3D G3DSA:2.30.110.10 2 156 6.4E-37 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_380 f0f2bd5b2116083fe708fd546a6bff2a 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 286 1.7E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 NPD12_953 87eb233497c6ecb74fc56b1e588322c1 324 SUPERFAMILY SSF55831 3 250 6.54E-51 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 NPD12_953 87eb233497c6ecb74fc56b1e588322c1 324 Pfam PF00303 Thymidylate synthase 51 250 8.4E-18 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 NPD12_953 87eb233497c6ecb74fc56b1e588322c1 324 Gene3D G3DSA:3.30.572.10 7 241 1.1E-52 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 NPD12_3313 57d952ccefd6303f7eb79b4be544ee77 260 Gene3D G3DSA:3.90.226.10 1 201 4.7E-75 T 12-10-2018 NPD12_3313 57d952ccefd6303f7eb79b4be544ee77 260 SUPERFAMILY SSF52096 3 256 1.12E-92 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily NPD12_3313 57d952ccefd6303f7eb79b4be544ee77 260 Gene3D G3DSA:1.10.12.10 203 257 8.7E-24 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal NPD12_3313 57d952ccefd6303f7eb79b4be544ee77 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 4.6E-76 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 NPD12_3313 57d952ccefd6303f7eb79b4be544ee77 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 NPD12_652 3dbae5c2be74e3f48ec0acc6a5e496d3 338 Gene3D G3DSA:2.120.10.30 203 337 1.7E-6 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like NPD12_652 3dbae5c2be74e3f48ec0acc6a5e496d3 338 SUPERFAMILY SSF82171 49 262 6.28E-10 T 12-10-2018 NPD12_652 3dbae5c2be74e3f48ec0acc6a5e496d3 338 Gene3D G3DSA:2.130.10.10 23 168 5.5E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 NPD12_2060 9940d9019ce43be58055d728c0954e40 172 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 172 2.2E-51 T 12-10-2018 IPR014198 Stage III sporulation protein AB NPD12_2060 9940d9019ce43be58055d728c0954e40 172 PIRSF PIRSF021435 1 172 3.4E-57 T 12-10-2018 IPR014198 Stage III sporulation protein AB NPD12_2060 9940d9019ce43be58055d728c0954e40 172 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 172 2.5E-48 T 12-10-2018 IPR014198 Stage III sporulation protein AB NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 Gene3D G3DSA:3.40.50.10490 227 418 1.3E-74 T 12-10-2018 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 8.7E-25 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 8.7E-25 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 8.7E-25 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 8.7E-25 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 8.7E-25 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 8.7E-25 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 Gene3D G3DSA:3.40.50.10490 40 226 6.2E-76 T 12-10-2018 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 Pfam PF00342 Phosphoglucose isomerase 77 427 1.8E-22 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 SUPERFAMILY SSF53697 7 448 1.93E-133 T 12-10-2018 NPD12_3407 c9fbf3119cea44075b56a1216868c0f0 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 2 436 24.593 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_78 5f8eb07b1cd924da321b7e1aea67ee59 325 Pfam PF01695 IstB-like ATP binding protein 156 289 4.6E-19 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 NPD12_78 5f8eb07b1cd924da321b7e1aea67ee59 325 Gene3D G3DSA:3.40.50.300 133 325 1.3E-35 T 12-10-2018 NPD12_78 5f8eb07b1cd924da321b7e1aea67ee59 325 SUPERFAMILY SSF52540 153 309 1.92E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_78 5f8eb07b1cd924da321b7e1aea67ee59 325 SMART SM00382 182 305 0.0023 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3764 01c40923038bb060e442ef3134494dbf 127 Pfam PF00436 Single-strand binding protein family 1 101 5.5E-32 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 NPD12_3764 01c40923038bb060e442ef3134494dbf 127 Hamap MF_00984 Single-stranded DNA-binding protein. 1 105 30.394 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 NPD12_3764 01c40923038bb060e442ef3134494dbf 127 SUPERFAMILY SSF50249 1 127 2.8E-40 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3764 01c40923038bb060e442ef3134494dbf 127 PIRSF PIRSF002070 1 117 4.1E-33 T 12-10-2018 NPD12_3764 01c40923038bb060e442ef3134494dbf 127 Gene3D G3DSA:2.40.50.140 1 111 8.4E-39 T 12-10-2018 NPD12_3764 01c40923038bb060e442ef3134494dbf 127 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 110 3.3E-32 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 NPD12_2136 dcb90867a8dcb052e1ccea0683baf5b5 355 Pfam PF01168 Alanine racemase, N-terminal domain 10 222 4.3E-19 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_2136 dcb90867a8dcb052e1ccea0683baf5b5 355 SUPERFAMILY SSF51419 10 229 6.02E-26 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_2136 dcb90867a8dcb052e1ccea0683baf5b5 355 Gene3D G3DSA:3.20.20.10 12 222 2.2E-24 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_189 fcb0962fcc4173e99bdb4c846baf72eb 187 SUPERFAMILY SSF88946 5 105 1.62E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_189 fcb0962fcc4173e99bdb4c846baf72eb 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 179 1.2E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_189 fcb0962fcc4173e99bdb4c846baf72eb 187 Gene3D G3DSA:1.10.1740.10 4 90 1.1E-14 T 12-10-2018 NPD12_189 fcb0962fcc4173e99bdb4c846baf72eb 187 Pfam PF08281 Sigma-70, region 4 123 175 2.5E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_189 fcb0962fcc4173e99bdb4c846baf72eb 187 Pfam PF04542 Sigma-70 region 2 24 91 3.5E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_189 fcb0962fcc4173e99bdb4c846baf72eb 187 SUPERFAMILY SSF88659 112 179 6.35E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_189 fcb0962fcc4173e99bdb4c846baf72eb 187 Gene3D G3DSA:1.10.10.10 109 180 4.8E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 Pfam PF00005 ABC transporter 395 543 5.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 Gene3D G3DSA:1.20.1560.10 16 364 9.8E-108 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 Pfam PF00664 ABC transporter transmembrane region 49 331 2.3E-60 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 Gene3D G3DSA:3.40.50.300 374 619 7.7E-89 T 12-10-2018 NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 SUPERFAMILY SSF90123 32 361 3.14E-89 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 SUPERFAMILY SSF52540 367 614 1.33E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2096 5e685fde1a34f35ee7198822e0ee9288 620 SMART SM00382 403 589 1.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 SUPERFAMILY SSF55136 128 290 1.02E-31 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 SUPERFAMILY SSF46689 57 108 9.86E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 SMART SM00871 128 288 9.8E-36 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 Pfam PF06445 GyrI-like small molecule binding domain 128 287 5.3E-28 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 Gene3D G3DSA:1.10.10.60 58 117 1.5E-13 T 12-10-2018 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 1.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 1.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 Gene3D G3DSA:3.20.80.10 128 290 3.7E-40 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 Pfam PF12833 Helix-turn-helix domain 28 104 4.3E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 SMART SM00342 21 104 3.4E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 Gene3D G3DSA:1.10.10.60 2 57 6.4E-15 T 12-10-2018 NPD12_918 f5deaf6a45fbf52102f9f13eef94380d 290 SUPERFAMILY SSF46689 5 55 3.85E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2886 0e1d9be607a321749cbeb1948545e321 276 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 169 2.7E-26 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 NPD12_2886 0e1d9be607a321749cbeb1948545e321 276 Gene3D G3DSA:3.30.465.10 4 172 2.4E-30 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 NPD12_2886 0e1d9be607a321749cbeb1948545e321 276 SUPERFAMILY SSF55447 179 274 5.49E-8 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily NPD12_2886 0e1d9be607a321749cbeb1948545e321 276 SUPERFAMILY SSF56176 1 169 1.06E-33 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_1251 61f417d085c41fed228466e420763c1a 680 PIRSF PIRSF006402 1 679 4.3E-247 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 NPD12_1251 61f417d085c41fed228466e420763c1a 680 Pfam PF03190 Protein of unknown function, DUF255 6 167 7.3E-79 T 12-10-2018 IPR004879 Domain of unknown function DUF255 NPD12_1251 61f417d085c41fed228466e420763c1a 680 Gene3D G3DSA:1.50.10.20 207 458 2.4E-5 T 12-10-2018 NPD12_1251 61f417d085c41fed228466e420763c1a 680 SUPERFAMILY SSF48208 182 535 2.11E-84 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 NPD12_1251 61f417d085c41fed228466e420763c1a 680 Gene3D G3DSA:1.50.10.20 459 587 1.0E-7 T 12-10-2018 NPD12_1251 61f417d085c41fed228466e420763c1a 680 Gene3D G3DSA:3.40.30.10 4 175 1.5E-75 T 12-10-2018 NPD12_1251 61f417d085c41fed228466e420763c1a 680 SUPERFAMILY SSF52833 6 145 1.26E-35 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_2258 201e88b8b5396e5c0569803df7f496ef 276 Gene3D G3DSA:3.20.80.10 133 274 4.3E-10 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2258 201e88b8b5396e5c0569803df7f496ef 276 Gene3D G3DSA:1.10.1660.10 4 132 2.1E-22 T 12-10-2018 NPD12_2258 201e88b8b5396e5c0569803df7f496ef 276 SUPERFAMILY SSF55136 213 272 2.07E-8 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_2258 201e88b8b5396e5c0569803df7f496ef 276 SUPERFAMILY SSF46955 5 108 2.38E-21 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_2258 201e88b8b5396e5c0569803df7f496ef 276 Pfam PF06445 GyrI-like small molecule binding domain 204 272 1.0E-8 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain NPD12_2258 201e88b8b5396e5c0569803df7f496ef 276 Pfam PF13411 MerR HTH family regulatory protein 6 74 3.4E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2258 201e88b8b5396e5c0569803df7f496ef 276 SMART SM00422 6 76 2.5E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1343 3fe1000adf20e70826a6f2ebcc362b58 311 SUPERFAMILY SSF52540 3 240 2.86E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1343 3fe1000adf20e70826a6f2ebcc362b58 311 Pfam PF08402 TOBE domain 248 309 5.9E-6 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 NPD12_1343 3fe1000adf20e70826a6f2ebcc362b58 311 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1343 3fe1000adf20e70826a6f2ebcc362b58 311 SMART SM00382 27 210 1.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1343 3fe1000adf20e70826a6f2ebcc362b58 311 Pfam PF00005 ABC transporter 18 160 1.7E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1343 3fe1000adf20e70826a6f2ebcc362b58 311 SUPERFAMILY SSF50331 243 309 3.66E-7 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal NPD12_1343 3fe1000adf20e70826a6f2ebcc362b58 311 Gene3D G3DSA:3.40.50.300 1 237 2.4E-76 T 12-10-2018 NPD12_1165 42f94705dae34a64385225f7d01733af 376 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 357 4.9E-59 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 NPD12_1165 42f94705dae34a64385225f7d01733af 376 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 148 176 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 NPD12_1165 42f94705dae34a64385225f7d01733af 376 PIRSF PIRSF000112 1 370 6.4E-84 T 12-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 NPD12_1165 42f94705dae34a64385225f7d01733af 376 Gene3D G3DSA:1.20.1090.10 158 376 3.0E-81 T 12-10-2018 NPD12_1165 42f94705dae34a64385225f7d01733af 376 Gene3D G3DSA:3.40.50.1970 2 157 3.3E-35 T 12-10-2018 NPD12_1165 42f94705dae34a64385225f7d01733af 376 SUPERFAMILY SSF56796 3 366 3.27E-77 T 12-10-2018 NPD12_3165 b2d30f9af3751a77ce61f52e8eff20dc 476 Pfam PF04055 Radical SAM superfamily 155 328 8.3E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3165 b2d30f9af3751a77ce61f52e8eff20dc 476 SMART SM00729 148 375 7.0E-52 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_3165 b2d30f9af3751a77ce61f52e8eff20dc 476 SUPERFAMILY SSF102114 145 462 4.97E-72 T 12-10-2018 NPD12_3165 b2d30f9af3751a77ce61f52e8eff20dc 476 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 67 470 2.1E-170 T 12-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ NPD12_3165 b2d30f9af3751a77ce61f52e8eff20dc 476 Gene3D G3DSA:3.80.30.20 112 470 3.0E-74 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_1236 689e7c1753b177a30e0438aa59892547 252 SMART SM00342 162 245 3.0E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 199 241 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 214 229 5.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 229 245 5.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 Gene3D G3DSA:1.10.10.60 195 248 4.5E-19 T 12-10-2018 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 Pfam PF12833 Helix-turn-helix domain 169 246 3.3E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 Gene3D G3DSA:1.10.10.60 144 194 7.4E-17 T 12-10-2018 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 SUPERFAMILY SSF46689 198 248 6.72E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1236 689e7c1753b177a30e0438aa59892547 252 SUPERFAMILY SSF46689 145 194 4.12E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 Gene3D G3DSA:2.40.50.140 1 67 1.0E-28 T 12-10-2018 NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 SUPERFAMILY SSF50249 1 66 1.51E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 SMART SM00357 3 67 8.4E-30 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 PIRSF PIRSF002599 1 67 9.5E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 PRINTS PR00050 Cold shock protein signature 4 19 2.1E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 PRINTS PR00050 Cold shock protein signature 40 58 2.1E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 PRINTS PR00050 Cold shock protein signature 24 33 2.1E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site NPD12_1650 ca8bfbb493563c7f161f7da59621ad77 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.7E-28 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 NPD12_890 b5b36d7508f650cc58b31a9e78c5a4ae 188 Gene3D G3DSA:3.40.50.300 1 188 1.3E-22 T 12-10-2018 NPD12_890 b5b36d7508f650cc58b31a9e78c5a4ae 188 SUPERFAMILY SSF52540 3 160 1.97E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_890 b5b36d7508f650cc58b31a9e78c5a4ae 188 Pfam PF06414 Zeta toxin 2 165 9.4E-8 T 12-10-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 NPD12_3242 dbce9092a78eb58735a063a8e1ca8412 447 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 30 418 1.2E-110 T 12-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 NPD12_3242 dbce9092a78eb58735a063a8e1ca8412 447 SUPERFAMILY SSF81324 209 304 3.61E-6 T 12-10-2018 NPD12_3242 dbce9092a78eb58735a063a8e1ca8412 447 Pfam PF02386 Cation transport protein 39 434 3.6E-61 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 NPD12_3229 592f7e35d68770d458e49af3eb81477e 337 SUPERFAMILY SSF51395 40 336 2.15E-61 T 12-10-2018 NPD12_3229 592f7e35d68770d458e49af3eb81477e 337 PIRSF PIRSF000138 2 196 3.9E-18 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 NPD12_3229 592f7e35d68770d458e49af3eb81477e 337 PIRSF PIRSF000138 185 337 2.8E-61 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 NPD12_3229 592f7e35d68770d458e49af3eb81477e 337 Gene3D G3DSA:3.20.20.70 36 337 7.9E-79 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3229 592f7e35d68770d458e49af3eb81477e 337 Pfam PF01070 FMN-dependent dehydrogenase 37 180 5.0E-12 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 NPD12_3229 592f7e35d68770d458e49af3eb81477e 337 Pfam PF01070 FMN-dependent dehydrogenase 194 336 8.8E-59 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 NPD12_3229 592f7e35d68770d458e49af3eb81477e 337 SMART SM01240 143 337 0.0016 T 12-10-2018 NPD12_3078 cdbadcdd6a6ab67bc308ea074ac82eb0 387 Pfam PF00589 Phage integrase family 179 371 5.3E-34 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 NPD12_3078 cdbadcdd6a6ab67bc308ea074ac82eb0 387 Gene3D G3DSA:1.10.443.10 173 385 1.1E-57 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 NPD12_3078 cdbadcdd6a6ab67bc308ea074ac82eb0 387 Gene3D G3DSA:1.10.150.130 60 172 1.0E-20 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal NPD12_3078 cdbadcdd6a6ab67bc308ea074ac82eb0 387 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 66 123 8.7E-9 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 NPD12_3078 cdbadcdd6a6ab67bc308ea074ac82eb0 387 SUPERFAMILY SSF56349 66 378 4.41E-67 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 Gene3D G3DSA:3.40.50.300 513 764 2.2E-84 T 12-10-2018 NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 SUPERFAMILY SSF52540 515 758 2.08E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 SMART SM00382 548 734 1.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 Gene3D G3DSA:1.20.1560.10 225 502 1.9E-65 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 Pfam PF00664 ABC transporter transmembrane region 248 475 1.8E-31 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 Pfam PF00005 ABC transporter 539 686 1.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 SUPERFAMILY SSF90123 4 507 1.15E-66 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_2097 45f76e5e74ab2fc804aace81dc3513ea 766 ProSitePatterns PS00211 ABC transporters family signature. 660 674 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1591 dfc99feba7754ae73644c85e64c2e618 137 Pfam PF02082 Transcriptional regulator 1 83 5.2E-24 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_1591 dfc99feba7754ae73644c85e64c2e618 137 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site NPD12_1591 dfc99feba7754ae73644c85e64c2e618 137 Gene3D G3DSA:1.10.10.10 1 137 5.7E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1591 dfc99feba7754ae73644c85e64c2e618 137 SUPERFAMILY SSF46785 2 134 6.77E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1591 dfc99feba7754ae73644c85e64c2e618 137 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 7.8E-31 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 SMART SM00535 23 156 2.5E-57 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 Gene3D G3DSA:1.10.1520.10 6 154 1.2E-47 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 Gene3D G3DSA:3.30.160.20 162 229 1.5E-22 T 12-10-2018 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 Pfam PF00035 Double-stranded RNA binding motif 163 229 1.3E-17 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 SMART SM00358 163 230 5.0E-21 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 ProSitePatterns PS00517 Ribonuclease III family signature. 45 53 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 SUPERFAMILY SSF69065 5 165 2.96E-49 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 226 30.247 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 12 229 1.5E-78 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 Pfam PF14622 Ribonuclease-III-like 21 147 2.9E-43 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 NPD12_2503 e57fa572e6e3223297b1f09e1925f476 234 SUPERFAMILY SSF54768 117 230 6.14E-24 T 12-10-2018 NPD12_2411 a540841d50de16ab61ce97db444cdcc0 278 Pfam PF00753 Metallo-beta-lactamase superfamily 25 114 1.8E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2411 a540841d50de16ab61ce97db444cdcc0 278 SUPERFAMILY SSF56281 12 278 2.17E-27 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2411 a540841d50de16ab61ce97db444cdcc0 278 Gene3D G3DSA:3.60.15.10 1 278 2.4E-83 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 Gene3D G3DSA:3.40.50.300 4 196 6.3E-44 T 12-10-2018 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 SUPERFAMILY SSF52540 4 169 5.81E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 6.4E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 6.4E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 156 3.2E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 Pfam PF07664 Ferrous iron transport protein B C terminus 458 510 5.1E-21 T 12-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 640 1.1E-179 T 12-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 Pfam PF02421 Ferrous iron transport protein B 4 157 1.2E-67 T 12-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 Pfam PF07670 Nucleoside recognition 515 643 8.3E-31 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_1222 9218a8d25adcdf5c93add976c423ee9b 718 Pfam PF07670 Nucleoside recognition 354 448 6.4E-12 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_3771 00c9371f90012ff8874588ca27a448d4 365 SUPERFAMILY SSF56563 87 363 6.41E-71 T 12-10-2018 NPD12_3771 00c9371f90012ff8874588ca27a448d4 365 Gene3D G3DSA:3.30.2320.10 225 356 6.9E-13 T 12-10-2018 NPD12_3771 00c9371f90012ff8874588ca27a448d4 365 Gene3D G3DSA:3.30.2400.10 129 354 6.9E-13 T 12-10-2018 NPD12_3771 00c9371f90012ff8874588ca27a448d4 365 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 25 363 2.6E-105 T 12-10-2018 IPR024455 Phage capsid NPD12_3771 00c9371f90012ff8874588ca27a448d4 365 Pfam PF05065 Phage capsid family 95 363 9.6E-80 T 12-10-2018 IPR024455 Phage capsid NPD12_3661 cdd499fe4d5caa3aa3948c6687586d39 250 Gene3D G3DSA:3.30.1360.170 1 215 7.1E-70 T 12-10-2018 NPD12_3661 cdd499fe4d5caa3aa3948c6687586d39 250 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 223 31.274 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_3661 cdd499fe4d5caa3aa3948c6687586d39 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 2 214 3.0E-60 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_3661 cdd499fe4d5caa3aa3948c6687586d39 250 Pfam PF02511 Thymidylate synthase complementing protein 4 209 7.4E-72 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_3661 cdd499fe4d5caa3aa3948c6687586d39 250 SUPERFAMILY SSF69796 1 224 4.97E-67 T 12-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 NPD12_3206 9df34c6116fcec51d11d514eee5247b1 375 Gene3D G3DSA:3.40.50.2000 17 188 2.1E-26 T 12-10-2018 NPD12_3206 9df34c6116fcec51d11d514eee5247b1 375 SUPERFAMILY SSF53756 20 374 1.45E-68 T 12-10-2018 NPD12_3206 9df34c6116fcec51d11d514eee5247b1 375 Pfam PF13477 Glycosyl transferase 4-like 20 157 8.2E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_3206 9df34c6116fcec51d11d514eee5247b1 375 Gene3D G3DSA:3.40.50.2000 189 375 1.2E-35 T 12-10-2018 NPD12_3206 9df34c6116fcec51d11d514eee5247b1 375 Pfam PF00534 Glycosyl transferases group 1 192 341 6.9E-35 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_3520 5ef84ab607a605378ff40e2a93ee470c 173 Gene3D G3DSA:3.40.430.10 2 173 1.3E-36 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 NPD12_3520 5ef84ab607a605378ff40e2a93ee470c 173 Pfam PF01872 RibD C-terminal domain 4 158 5.7E-19 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 NPD12_3520 5ef84ab607a605378ff40e2a93ee470c 173 SUPERFAMILY SSF53597 4 170 1.2E-28 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 NPD12_2470 5b0b4042e89246cd16f8b8a226bf9982 153 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 8 153 23.835 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 NPD12_2470 5b0b4042e89246cd16f8b8a226bf9982 153 Pfam PF02576 RimP N-terminal domain 14 85 8.9E-29 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal NPD12_2470 5b0b4042e89246cd16f8b8a226bf9982 153 Gene3D G3DSA:3.30.300.70 2 82 6.1E-29 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily NPD12_2470 5b0b4042e89246cd16f8b8a226bf9982 153 Gene3D G3DSA:2.30.30.180 89 149 1.0E-9 T 12-10-2018 NPD12_2470 5b0b4042e89246cd16f8b8a226bf9982 153 Pfam PF17384 RimP C-terminal SH3 domain 88 152 1.5E-12 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal NPD12_2470 5b0b4042e89246cd16f8b8a226bf9982 153 SUPERFAMILY SSF75420 4 85 1.57E-26 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily NPD12_2470 5b0b4042e89246cd16f8b8a226bf9982 153 SUPERFAMILY SSF74942 86 149 8.37E-14 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily NPD12_1468 fbe927c11ff429a134f727f15b476ead 560 Pfam PF12705 PD-(D/E)XK nuclease superfamily 3 237 5.8E-18 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type NPD12_1468 fbe927c11ff429a134f727f15b476ead 560 Pfam PF13479 AAA domain 259 461 8.3E-48 T 12-10-2018 NPD12_611 0350acd05fc77b9b9a07fa1def505fd3 157 Pfam PF12681 Glyoxalase-like domain 3 121 4.0E-52 T 12-10-2018 IPR025870 Glyoxalase-like domain NPD12_611 0350acd05fc77b9b9a07fa1def505fd3 157 Gene3D G3DSA:3.10.180.10 1 156 2.4E-57 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_611 0350acd05fc77b9b9a07fa1def505fd3 157 SUPERFAMILY SSF54593 1 118 1.23E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_3491 4841103a0323e998a0d200082869847e 190 Pfam PF08281 Sigma-70, region 4 120 173 3.3E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_3491 4841103a0323e998a0d200082869847e 190 Pfam PF04542 Sigma-70 region 2 23 88 1.4E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_3491 4841103a0323e998a0d200082869847e 190 Gene3D G3DSA:1.10.1740.10 2 105 2.2E-21 T 12-10-2018 NPD12_3491 4841103a0323e998a0d200082869847e 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 176 3.5E-27 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_3491 4841103a0323e998a0d200082869847e 190 SUPERFAMILY SSF88659 110 177 1.4E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_3491 4841103a0323e998a0d200082869847e 190 Gene3D G3DSA:1.10.10.10 109 181 5.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3491 4841103a0323e998a0d200082869847e 190 SUPERFAMILY SSF88946 3 98 4.97E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_263 a69e5f9cc9db8f8f008ce4ebea24d2c2 371 Pfam PF13439 Glycosyltransferase Family 4 80 170 5.3E-8 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 NPD12_263 a69e5f9cc9db8f8f008ce4ebea24d2c2 371 Gene3D G3DSA:3.40.50.2000 181 370 4.1E-47 T 12-10-2018 NPD12_263 a69e5f9cc9db8f8f008ce4ebea24d2c2 371 Gene3D G3DSA:3.40.50.2000 16 180 7.7E-9 T 12-10-2018 NPD12_263 a69e5f9cc9db8f8f008ce4ebea24d2c2 371 SUPERFAMILY SSF53756 46 370 1.48E-74 T 12-10-2018 NPD12_263 a69e5f9cc9db8f8f008ce4ebea24d2c2 371 Pfam PF00534 Glycosyl transferases group 1 187 348 3.9E-34 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 NPD12_3492 e5dcfb22b9c7090a9a892608561929e2 552 Pfam PF01740 STAS domain 443 542 2.6E-12 T 12-10-2018 IPR002645 STAS domain NPD12_3492 e5dcfb22b9c7090a9a892608561929e2 552 Gene3D G3DSA:3.30.750.24 428 550 1.0E-24 T 12-10-2018 IPR036513 STAS domain superfamily NPD12_3492 e5dcfb22b9c7090a9a892608561929e2 552 Pfam PF00916 Sulfate permease family 22 385 5.7E-87 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 NPD12_3492 e5dcfb22b9c7090a9a892608561929e2 552 SUPERFAMILY SSF52091 442 546 2.55E-13 T 12-10-2018 IPR036513 STAS domain superfamily NPD12_2241 6e5116b007d8ff5c23cba2619b6a226d 216 Pfam PF06130 Phosphate propanoyltransferase 32 110 6.6E-28 T 12-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 NPD12_2241 6e5116b007d8ff5c23cba2619b6a226d 216 Pfam PF06130 Phosphate propanoyltransferase 140 206 1.3E-17 T 12-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 NPD12_2241 6e5116b007d8ff5c23cba2619b6a226d 216 PIRSF PIRSF010130 1 216 4.2E-88 T 12-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 NPD12_3645 77f2500bda3e9d4a578441bad7200878 80 Gene3D G3DSA:3.30.1330.30 5 79 2.2E-19 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_3645 77f2500bda3e9d4a578441bad7200878 80 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 10 76 7.4E-13 T 12-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 NPD12_3645 77f2500bda3e9d4a578441bad7200878 80 SUPERFAMILY SSF55315 7 79 1.94E-17 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 SUPERFAMILY SSF69618 249 484 6.54E-49 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 Gene3D G3DSA:3.40.50.10090 280 411 4.0E-24 T 12-10-2018 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 Gene3D G3DSA:3.40.50.10090 415 486 3.4E-8 T 12-10-2018 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 211 6.2E-41 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 SUPERFAMILY SSF53790 1 251 7.46E-71 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 Pfam PF02602 Uroporphyrinogen-III synthase HemD 263 479 2.0E-49 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 236 3.3E-91 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 Gene3D G3DSA:3.40.1010.10 1 117 1.5E-37 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 NPD12_1106 e7dde140b83df0b3181c059ec97719e7 486 Gene3D G3DSA:3.30.950.10 118 266 3.8E-42 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 467 2.2E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 Gene3D G3DSA:1.10.287.130 252 314 3.5E-18 T 12-10-2018 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 SMART SM00388 247 313 2.0E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 SMART SM00387 359 469 6.1E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 1.8E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 1.8E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 1.8E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 1.8E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 Gene3D G3DSA:1.20.1480.50 154 250 3.1E-17 T 12-10-2018 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 Pfam PF00672 HAMP domain 194 242 9.6E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 Gene3D G3DSA:3.30.565.10 318 469 4.2E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 313 1.3E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 SUPERFAMILY SSF47384 230 314 9.61E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 SMART SM00304 194 246 4.6E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 SUPERFAMILY SSF158472 194 243 2.62E-11 T 12-10-2018 NPD12_12 d7a2ceb204f9b512406ffe4a859ceb0b 469 SUPERFAMILY SSF55874 302 467 4.58E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_3486 eab4b94aae40d0a138855da8a8a26614 80 SUPERFAMILY SSF82771 2 71 4.97E-15 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_3486 eab4b94aae40d0a138855da8a8a26614 80 Gene3D G3DSA:3.40.1440.10 1 80 7.1E-33 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 NPD12_3486 eab4b94aae40d0a138855da8a8a26614 80 Pfam PF01541 GIY-YIG catalytic domain 1 72 2.4E-18 T 12-10-2018 IPR000305 GIY-YIG endonuclease NPD12_2153 19b0b6157ce211c279b376bed52bb638 465 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 125 456 9.9E-114 T 12-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 NPD12_2153 19b0b6157ce211c279b376bed52bb638 465 Gene3D G3DSA:3.40.50.2300 1 105 3.0E-40 T 12-10-2018 NPD12_2153 19b0b6157ce211c279b376bed52bb638 465 SUPERFAMILY SSF52794 3 103 1.29E-36 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 NPD12_2153 19b0b6157ce211c279b376bed52bb638 465 Pfam PF02378 Phosphotransferase system, EIIC 137 404 9.1E-18 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_2153 19b0b6157ce211c279b376bed52bb638 465 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 95 4.0E-16 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 NPD12_2153 19b0b6157ce211c279b376bed52bb638 465 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 87 7.6E-31 T 12-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 NPD12_907 f0c813d764795be2ae8cb376496e6120 488 SMART SM00283 216 463 2.1E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_907 f0c813d764795be2ae8cb376496e6120 488 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 285 414 6.7E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_907 f0c813d764795be2ae8cb376496e6120 488 Gene3D G3DSA:1.10.287.950 187 487 2.7E-49 T 12-10-2018 NPD12_907 f0c813d764795be2ae8cb376496e6120 488 SUPERFAMILY SSF58104 222 485 2.09E-51 T 12-10-2018 NPD12_3303 15c7bd576f0efcb247d6afb36cdd6ec6 66 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 4.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 NPD12_3303 15c7bd576f0efcb247d6afb36cdd6ec6 66 PRINTS PR00352 3Fe-4S ferredoxin signature 51 63 4.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 NPD12_3303 15c7bd576f0efcb247d6afb36cdd6ec6 66 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 4.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 NPD12_3303 15c7bd576f0efcb247d6afb36cdd6ec6 66 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 65 1.0E-19 T 12-10-2018 NPD12_3303 15c7bd576f0efcb247d6afb36cdd6ec6 66 Gene3D G3DSA:3.30.70.20 2 66 1.7E-21 T 12-10-2018 NPD12_3303 15c7bd576f0efcb247d6afb36cdd6ec6 66 SUPERFAMILY SSF54862 3 65 1.96E-13 T 12-10-2018 NPD12_221 ec6eee914919058cf4df8e3a45eaeff9 81 SMART SM00966 8 51 3.4E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 NPD12_221 ec6eee914919058cf4df8e3a45eaeff9 81 SUPERFAMILY SSF89447 1 53 2.75E-16 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily NPD12_221 ec6eee914919058cf4df8e3a45eaeff9 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 3.6E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 NPD12_221 ec6eee914919058cf4df8e3a45eaeff9 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.0E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 NPD12_221 ec6eee914919058cf4df8e3a45eaeff9 81 Gene3D G3DSA:2.10.260.10 1 51 1.1E-25 T 12-10-2018 NPD12_357 958b00b13d8aa8cae15b210866ae1033 138 SMART SM00116 10 57 6.9E-12 T 12-10-2018 IPR000644 CBS domain NPD12_357 958b00b13d8aa8cae15b210866ae1033 138 SMART SM00116 74 121 4.9E-10 T 12-10-2018 IPR000644 CBS domain NPD12_357 958b00b13d8aa8cae15b210866ae1033 138 Gene3D G3DSA:3.10.580.10 1 137 1.6E-41 T 12-10-2018 NPD12_357 958b00b13d8aa8cae15b210866ae1033 138 SUPERFAMILY SSF54631 1 116 2.65E-36 T 12-10-2018 NPD12_357 958b00b13d8aa8cae15b210866ae1033 138 Pfam PF00571 CBS domain 67 117 2.2E-14 T 12-10-2018 IPR000644 CBS domain NPD12_357 958b00b13d8aa8cae15b210866ae1033 138 Pfam PF00571 CBS domain 3 53 3.6E-15 T 12-10-2018 IPR000644 CBS domain NPD12_1239 ac1276221a3a89762ea1ffea038551f8 251 Pfam PF00005 ABC transporter 18 164 2.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1239 ac1276221a3a89762ea1ffea038551f8 251 SMART SM00382 26 243 7.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1239 ac1276221a3a89762ea1ffea038551f8 251 SUPERFAMILY SSF52540 1 226 6.83E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1239 ac1276221a3a89762ea1ffea038551f8 251 Gene3D G3DSA:3.40.50.300 1 250 1.8E-67 T 12-10-2018 NPD12_646 1dfdfd919938824ab27ebaa580816abf 273 SUPERFAMILY SSF54001 27 134 7.85E-45 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_646 1dfdfd919938824ab27ebaa580816abf 273 Gene3D G3DSA:3.90.1720.10 20 139 1.7E-50 T 12-10-2018 NPD12_646 1dfdfd919938824ab27ebaa580816abf 273 SUPERFAMILY SSF47090 145 208 2.75E-5 T 12-10-2018 IPR036365 PGBD-like superfamily NPD12_646 1dfdfd919938824ab27ebaa580816abf 273 Pfam PF00877 NlpC/P60 family 43 132 9.0E-28 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 SUPERFAMILY SSF54556 338 422 5.04E-19 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 ProSitePatterns PS01095 Chitinases family 18 active site. 189 197 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 Gene3D G3DSA:3.10.50.10 337 422 4.6E-98 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 SMART SM00636 52 451 1.0E-115 T 12-10-2018 IPR011583 Chitinase II GO:0008061 NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 Gene3D G3DSA:2.60.40.290 500 606 1.2E-9 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 SUPERFAMILY SSF49384 504 608 6.07E-12 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 SUPERFAMILY SSF51445 51 453 1.02E-79 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 Pfam PF00704 Glycosyl hydrolases family 18 54 451 3.8E-84 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 Gene3D G3DSA:3.20.20.80 55 451 4.6E-98 T 12-10-2018 NPD12_916 100ce3812c27c568bb54fa4b5ad6d5f7 617 Pfam PF06483 Chitinase C 469 595 3.2E-7 T 12-10-2018 IPR009470 Chitinase, C-terminal KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 NPD12_1515 5966e803e34bcbd2217ad5167796934b 255 Gene3D G3DSA:3.40.630.40 1 176 1.8E-41 T 12-10-2018 NPD12_1515 5966e803e34bcbd2217ad5167796934b 255 Pfam PF08239 Bacterial SH3 domain 203 253 1.1E-10 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_1515 5966e803e34bcbd2217ad5167796934b 255 SMART SM00646 67 171 2.7E-14 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_1515 5966e803e34bcbd2217ad5167796934b 255 SMART SM00287 194 251 1.5E-4 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_1515 5966e803e34bcbd2217ad5167796934b 255 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 170 4.7E-23 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_1515 5966e803e34bcbd2217ad5167796934b 255 Gene3D G3DSA:2.30.30.40 194 253 1.6E-16 T 12-10-2018 NPD12_1515 5966e803e34bcbd2217ad5167796934b 255 SUPERFAMILY SSF53187 3 172 3.77E-31 T 12-10-2018 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 Pfam PF00403 Heavy-metal-associated domain 7 64 5.4E-15 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 Gene3D G3DSA:3.30.70.100 1 65 6.8E-19 T 12-10-2018 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 SUPERFAMILY SSF55008 2 65 2.49E-16 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 PRINTS PR00944 Copper ion binding protein signature 14 27 5.9E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 PRINTS PR00944 Copper ion binding protein signature 27 40 5.9E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 PRINTS PR00944 Copper ion binding protein signature 52 65 5.9E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 NPD12_1553 1d7ed1d22f1798dea62c006e30ca7495 71 PRINTS PR00944 Copper ion binding protein signature 2 14 5.9E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 NPD12_3395 d4a23d4fcf4269446d71589aa65c78b2 485 SUPERFAMILY SSF75304 1 482 7.59E-162 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 NPD12_3395 d4a23d4fcf4269446d71589aa65c78b2 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 3.6E-197 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 NPD12_3395 d4a23d4fcf4269446d71589aa65c78b2 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 NPD12_3395 d4a23d4fcf4269446d71589aa65c78b2 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 93.948 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 NPD12_3395 d4a23d4fcf4269446d71589aa65c78b2 485 Pfam PF01425 Amidase 24 464 1.9E-160 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 NPD12_3395 d4a23d4fcf4269446d71589aa65c78b2 485 Gene3D G3DSA:3.90.1300.10 2 485 4.1E-193 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 Pfam PF00563 EAL domain 8 193 5.1E-18 T 12-10-2018 IPR001633 EAL domain NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 Pfam PF08668 HDOD domain 209 322 4.7E-12 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 SUPERFAMILY SSF109604 184 401 3.77E-36 T 12-10-2018 NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 PIRSF PIRSF003180 1 403 1.2E-121 T 12-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 Gene3D G3DSA:3.20.20.450 2 196 2.4E-20 T 12-10-2018 IPR035919 EAL domain superfamily NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 SUPERFAMILY SSF141868 4 201 5.89E-29 T 12-10-2018 IPR035919 EAL domain superfamily NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 Gene3D G3DSA:1.10.3210.10 197 327 1.4E-16 T 12-10-2018 NPD12_616 ca92420a4e06eb790fc50e8530da939b 403 SMART SM00052 1 198 9.8E-6 T 12-10-2018 IPR001633 EAL domain NPD12_3277 c182ccf008b8e92e58037494ebe931a4 168 Pfam PF00583 Acetyltransferase (GNAT) family 44 140 4.0E-21 T 12-10-2018 IPR000182 GNAT domain NPD12_3277 c182ccf008b8e92e58037494ebe931a4 168 Gene3D G3DSA:3.40.630.30 3 165 6.2E-40 T 12-10-2018 NPD12_3277 c182ccf008b8e92e58037494ebe931a4 168 SUPERFAMILY SSF55729 3 164 1.28E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_904 60a0176bb6260a6e3a475dccee1ab7b7 293 SUPERFAMILY SSF103481 39 137 8.76E-14 T 12-10-2018 NPD12_904 60a0176bb6260a6e3a475dccee1ab7b7 293 Pfam PF00892 EamA-like transporter family 8 134 3.6E-15 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_904 60a0176bb6260a6e3a475dccee1ab7b7 293 Pfam PF00892 EamA-like transporter family 147 279 2.0E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_904 60a0176bb6260a6e3a475dccee1ab7b7 293 SUPERFAMILY SSF103481 186 279 4.97E-13 T 12-10-2018 NPD12_140 8af6427c1e2c0f58b04b8b77349d4891 150 Gene3D G3DSA:1.10.3210.10 15 149 7.2E-13 T 12-10-2018 NPD12_140 8af6427c1e2c0f58b04b8b77349d4891 150 TIGRFAM TIGR00277 HDIG: HDIG domain 30 132 1.1E-7 T 12-10-2018 IPR006675 HDIG domain NPD12_140 8af6427c1e2c0f58b04b8b77349d4891 150 SUPERFAMILY SSF109604 27 150 2.42E-10 T 12-10-2018 NPD12_140 8af6427c1e2c0f58b04b8b77349d4891 150 Pfam PF01966 HD domain 30 138 2.0E-8 T 12-10-2018 IPR006674 HD domain NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 Pfam PF00271 Helicase conserved C-terminal domain 229 337 6.3E-33 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 Gene3D G3DSA:3.30.70.330 406 481 5.5E-26 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 SMART SM00490 256 337 3.5E-35 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 Pfam PF03880 DbpA RNA binding domain 408 477 2.0E-22 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 SUPERFAMILY SSF52540 72 358 5.49E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 ProSitePatterns PS00563 Stathmin family signature 1. 366 375 - T 12-10-2018 IPR030514 Stathmin, conserved site NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 Pfam PF00270 DEAD/DEAH box helicase 29 193 1.3E-49 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 Gene3D G3DSA:3.40.50.300 210 380 1.0E-52 T 12-10-2018 NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 SMART SM00487 23 215 1.5E-61 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 6 480 68.741 T 12-10-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 NPD12_1932 c772852d0234ac4063abc00abcbdc46d 481 Gene3D G3DSA:3.40.50.300 5 209 2.7E-75 T 12-10-2018 NPD12_1642 85eb4e42edc155e52fbffaef1021fb04 385 Gene3D G3DSA:3.30.565.10 260 379 7.2E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1642 85eb4e42edc155e52fbffaef1021fb04 385 SUPERFAMILY SSF55874 295 379 1.1E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1642 85eb4e42edc155e52fbffaef1021fb04 385 Pfam PF07730 Histidine kinase 187 252 9.1E-18 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 NPD12_3263 205c9f6da0dd75da0cdb1c81f6653845 560 Gene3D G3DSA:3.10.105.10 300 529 9.8E-165 T 12-10-2018 NPD12_3263 205c9f6da0dd75da0cdb1c81f6653845 560 Gene3D G3DSA:3.40.190.10 53 546 9.8E-165 T 12-10-2018 NPD12_3263 205c9f6da0dd75da0cdb1c81f6653845 560 SUPERFAMILY SSF53850 35 551 2.61E-116 T 12-10-2018 NPD12_3263 205c9f6da0dd75da0cdb1c81f6653845 560 PIRSF PIRSF002741 2 557 6.0E-98 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 NPD12_3263 205c9f6da0dd75da0cdb1c81f6653845 560 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 473 2.4E-79 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain NPD12_3263 205c9f6da0dd75da0cdb1c81f6653845 560 Gene3D G3DSA:3.90.76.10 72 197 9.8E-165 T 12-10-2018 NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 SUPERFAMILY SSF56228 1 209 3.79E-75 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 Gene3D G3DSA:1.10.599.10 239 600 4.8E-144 T 12-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 Gene3D G3DSA:1.10.569.10 241 427 4.8E-144 T 12-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 2.9E-79 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 SUPERFAMILY SSF48310 210 603 8.37E-140 T 12-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 225 600 4.0E-142 T 12-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 Gene3D G3DSA:3.60.9.10 1 210 5.3E-86 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily NPD12_2102 acb0a636931c0495c96b39db91bcc2a0 605 SMART SM00790 4 206 3.1E-119 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 NPD12_947 9c69883c5e87bc4f36146dd79dcd240a 416 Pfam PF06597 Clostridium P-47 protein 3 320 1.1E-28 T 12-10-2018 IPR010567 Clostridium P47 protein NPD12_1796 0b380712e6f6736e496910323c36ce4e 196 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 73 89 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 NPD12_1796 0b380712e6f6736e496910323c36ce4e 196 SUPERFAMILY SSF55620 3 192 2.45E-58 T 12-10-2018 NPD12_1796 0b380712e6f6736e496910323c36ce4e 196 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 4 195 34.838 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 NPD12_1796 0b380712e6f6736e496910323c36ce4e 196 Gene3D G3DSA:1.10.286.10 1 51 9.4E-19 T 12-10-2018 NPD12_1796 0b380712e6f6736e496910323c36ce4e 196 Pfam PF01227 GTP cyclohydrolase I 8 193 2.2E-68 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 NPD12_1796 0b380712e6f6736e496910323c36ce4e 196 Gene3D G3DSA:3.30.1130.10 64 196 5.5E-45 T 12-10-2018 NPD12_1796 0b380712e6f6736e496910323c36ce4e 196 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 8 184 1.0E-57 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 77 93 9.2E-44 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 308 324 9.2E-44 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 111 131 9.2E-44 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 397 412 9.2E-44 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 148 165 9.2E-44 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 265 283 9.2E-44 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 SUPERFAMILY SSF101821 89 216 3.2E-36 T 12-10-2018 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 Gene3D G3DSA:2.30.250.10 87 220 6.1E-163 T 12-10-2018 IPR023358 Peptidase M18, domain 2 GO:0004177 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 13 430 7.2E-135 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 Gene3D G3DSA:3.40.630.10 9 429 6.1E-163 T 12-10-2018 NPD12_3479 e18ae71eea902e6a0c528b973bd7f5f9 432 SUPERFAMILY SSF53187 5 430 5.15E-99 T 12-10-2018 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 Gene3D G3DSA:3.40.1690.10 474 609 5.7E-54 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 Pfam PF01312 FlhB HrpN YscU SpaS Family 263 602 2.0E-129 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 464 482 1.3E-38 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 557 578 1.3E-38 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 484 501 1.3E-38 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 528 543 1.3E-38 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 266 288 1.3E-38 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 9 246 1.7E-50 T 12-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 263 608 6.1E-129 T 12-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 Pfam PF01311 Bacterial export proteins, family 1 8 240 2.4E-57 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 NPD12_2696 49a1b7872167ffe83cdd7e0d211b0c9b 609 SUPERFAMILY SSF160544 500 606 5.76E-39 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal NPD12_1027 8fb7750e7ea049a6a8120cd6af897479 305 Pfam PF00005 ABC transporter 20 164 1.8E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1027 8fb7750e7ea049a6a8120cd6af897479 305 SMART SM00382 29 230 8.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1027 8fb7750e7ea049a6a8120cd6af897479 305 Gene3D G3DSA:3.40.50.300 1 242 8.1E-61 T 12-10-2018 NPD12_1027 8fb7750e7ea049a6a8120cd6af897479 305 SUPERFAMILY SSF52540 3 227 4.37E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2901 c36386b2e75dbcff20084ce6f2bd1627 123 Gene3D G3DSA:3.10.450.540 24 121 4.0E-5 T 12-10-2018 NPD12_2901 c36386b2e75dbcff20084ce6f2bd1627 123 Pfam PF12642 Conjugative transposon protein TcpC 25 119 6.6E-27 T 12-10-2018 IPR024735 Conjugative transposon protein TcpC NPD12_92 b8135a25e479e5ac26e68ed5ac83b4e1 409 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 404 8.5E-138 T 12-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like NPD12_92 b8135a25e479e5ac26e68ed5ac83b4e1 409 Gene3D G3DSA:3.50.50.60 6 400 5.9E-127 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_92 b8135a25e479e5ac26e68ed5ac83b4e1 409 SUPERFAMILY SSF160996 189 352 4.97E-43 T 12-10-2018 NPD12_92 b8135a25e479e5ac26e68ed5ac83b4e1 409 Pfam PF03486 HI0933-like protein 4 404 1.5E-128 T 12-10-2018 NPD12_92 b8135a25e479e5ac26e68ed5ac83b4e1 409 SUPERFAMILY SSF51905 4 406 1.41E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_92 b8135a25e479e5ac26e68ed5ac83b4e1 409 Gene3D G3DSA:1.10.8.260 269 334 5.9E-127 T 12-10-2018 IPR023166 HI0933-like insert domain superfamily NPD12_92 b8135a25e479e5ac26e68ed5ac83b4e1 409 Gene3D G3DSA:2.40.30.10 188 351 5.9E-127 T 12-10-2018 NPD12_931 5e1901ff5140b7fd8d4f92e20d09cba0 285 Pfam PF13529 Peptidase_C39 like family 110 258 1.2E-10 T 12-10-2018 IPR039564 Peptidase C39-like NPD12_1186 2af48568f740d5bfb045d1dcd65adbc9 143 Gene3D G3DSA:1.20.1260.10 15 141 8.1E-24 T 12-10-2018 IPR012347 Ferritin-like NPD12_1186 2af48568f740d5bfb045d1dcd65adbc9 143 Pfam PF02915 Rubrerythrin 28 79 1.2E-7 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 NPD12_1186 2af48568f740d5bfb045d1dcd65adbc9 143 Pfam PF02915 Rubrerythrin 85 142 2.1E-5 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 NPD12_1186 2af48568f740d5bfb045d1dcd65adbc9 143 SUPERFAMILY SSF47240 18 142 3.63E-30 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_3170 5f854db0be137a903fbb0fc2f512793d 292 Pfam PF01368 DHH family 42 189 4.5E-8 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 NPD12_3170 5f854db0be137a903fbb0fc2f512793d 292 Gene3D G3DSA:3.90.1640.30 16 283 5.5E-66 T 12-10-2018 NPD12_3170 5f854db0be137a903fbb0fc2f512793d 292 SUPERFAMILY SSF64182 18 282 4.58E-56 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily NPD12_2702 e93973d36fda1d6ffece5c7af13f2583 270 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 188 205 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site NPD12_2702 e93973d36fda1d6ffece5c7af13f2583 270 Pfam PF01618 MotA/TolQ/ExbB proton channel family 104 218 1.7E-25 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel NPD12_3741 9a403f87da72d44d162a5eff8fd3d1a2 234 Gene3D G3DSA:1.10.10.10 15 135 3.3E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3741 9a403f87da72d44d162a5eff8fd3d1a2 234 Pfam PF13730 Helix-turn-helix domain 34 88 2.3E-7 T 12-10-2018 NPD12_675 841438d29c5f6a305742e9f8530846ea 674 SUPERFAMILY SSF103190 46 184 9.68E-5 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_675 841438d29c5f6a305742e9f8530846ea 674 SMART SM00283 389 672 9.0E-21 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_675 841438d29c5f6a305742e9f8530846ea 674 Pfam PF02743 Cache domain 42 277 2.3E-19 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_675 841438d29c5f6a305742e9f8530846ea 674 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 448 564 2.8E-26 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_675 841438d29c5f6a305742e9f8530846ea 674 SUPERFAMILY SSF58104 335 671 2.62E-52 T 12-10-2018 NPD12_675 841438d29c5f6a305742e9f8530846ea 674 Gene3D G3DSA:3.30.450.20 148 296 1.0E-21 T 12-10-2018 NPD12_675 841438d29c5f6a305742e9f8530846ea 674 Gene3D G3DSA:1.10.287.950 314 652 1.5E-53 T 12-10-2018 NPD12_3543 8e6bd29b188c1ed13f9425d26070c3ab 417 Gene3D G3DSA:2.30.42.10 288 371 1.1E-9 T 12-10-2018 NPD12_3543 8e6bd29b188c1ed13f9425d26070c3ab 417 SUPERFAMILY SSF50156 299 360 6.18E-11 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 NPD12_3543 8e6bd29b188c1ed13f9425d26070c3ab 417 Pfam PF13180 PDZ domain 305 348 2.8E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_3543 8e6bd29b188c1ed13f9425d26070c3ab 417 SMART SM00228 289 363 4.0E-4 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_2965 421f418c76abadc951054dde6d263d79 93 SUPERFAMILY SSF103007 1 93 2.75E-32 T 12-10-2018 IPR036746 TT1725-like superfamily NPD12_2965 421f418c76abadc951054dde6d263d79 93 Gene3D G3DSA:3.30.70.1120 1 93 2.4E-26 T 12-10-2018 IPR036746 TT1725-like superfamily NPD12_2965 421f418c76abadc951054dde6d263d79 93 Pfam PF04456 Protein of unknown function (DUF503) 3 89 1.4E-32 T 12-10-2018 IPR007546 Protein of unknown function DUF503 NPD12_3134 b4ea6fee2ca6c2e6748fce189c9d1dc9 449 ProSitePatterns PS00018 EF-hand calcium-binding domain. 395 407 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site NPD12_3134 b4ea6fee2ca6c2e6748fce189c9d1dc9 449 Gene3D G3DSA:3.40.50.1460 199 447 4.1E-26 T 12-10-2018 NPD12_3134 b4ea6fee2ca6c2e6748fce189c9d1dc9 449 SUPERFAMILY SSF52129 193 391 2.93E-10 T 12-10-2018 IPR029030 Caspase-like domain superfamily NPD12_3134 b4ea6fee2ca6c2e6748fce189c9d1dc9 449 Pfam PF00656 Caspase domain 203 399 2.1E-18 T 12-10-2018 NPD12_2710 3deb6094e170d6aac53d915df854fad3 260 Pfam PF02108 Flagellar assembly protein FliH 126 251 7.9E-7 T 12-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 Pfam PF02629 CoA binding domain 83 179 1.1E-23 T 12-10-2018 IPR003781 CoA-binding GO:0048037 NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 Gene3D G3DSA:1.10.10.10 1 77 3.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 Pfam PF06971 Putative DNA-binding protein N-terminus 6 54 7.3E-21 T 12-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 SUPERFAMILY SSF51735 82 207 3.35E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 210 36.211 T 12-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 Gene3D G3DSA:3.40.50.720 78 210 1.7E-49 T 12-10-2018 NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 SUPERFAMILY SSF46785 10 80 1.32E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3434 5abc5b89cab047b4cf2c38faaadb0ca2 210 SMART SM00881 81 181 4.6E-20 T 12-10-2018 IPR003781 CoA-binding GO:0048037 NPD12_28 cf14cc07eb01c5f86aa82bcbd9b5f83f 298 Pfam PF13353 4Fe-4S single cluster domain 55 152 4.5E-6 T 12-10-2018 NPD12_28 cf14cc07eb01c5f86aa82bcbd9b5f83f 298 SUPERFAMILY SSF102114 60 189 2.62E-11 T 12-10-2018 NPD12_28 cf14cc07eb01c5f86aa82bcbd9b5f83f 298 Gene3D G3DSA:3.20.20.70 46 263 1.5E-15 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_28 cf14cc07eb01c5f86aa82bcbd9b5f83f 298 Pfam PF04055 Radical SAM superfamily 56 224 8.7E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_28 cf14cc07eb01c5f86aa82bcbd9b5f83f 298 PIRSF PIRSF004869 1 291 1.8E-77 T 12-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted NPD12_963 0cf09bd9aa7c7d853da859d44629679c 263 Pfam PF12730 ABC-2 family transporter protein 4 201 3.2E-14 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_2756 4e27d432aa4ce2172d57aa52698c5120 236 Pfam PF02348 Cytidylyltransferase 8 196 1.9E-25 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 NPD12_2756 4e27d432aa4ce2172d57aa52698c5120 236 Gene3D G3DSA:3.90.550.10 2 232 3.6E-70 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2756 4e27d432aa4ce2172d57aa52698c5120 236 SUPERFAMILY SSF53448 4 230 3.67E-54 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_3538 b0020679e7b9cfe248c4b1f8d0673f0e 476 Gene3D G3DSA:3.40.710.10 141 470 3.5E-127 T 12-10-2018 NPD12_3538 b0020679e7b9cfe248c4b1f8d0673f0e 476 Pfam PF00905 Penicillin binding protein transpeptidase domain 159 470 3.6E-71 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 NPD12_3538 b0020679e7b9cfe248c4b1f8d0673f0e 476 Gene3D G3DSA:3.90.1310.10 64 376 3.5E-127 T 12-10-2018 NPD12_3538 b0020679e7b9cfe248c4b1f8d0673f0e 476 ProSitePatterns PS00337 Beta-lactamase class-D active site. 211 221 - T 12-10-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 NPD12_3538 b0020679e7b9cfe248c4b1f8d0673f0e 476 SUPERFAMILY SSF56601 142 474 2.66E-92 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_3538 b0020679e7b9cfe248c4b1f8d0673f0e 476 SUPERFAMILY SSF56519 44 115 5.98E-9 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 NPD12_1155 a2783c8f40bd9e136e21253cfdcce33e 340 Pfam PF01497 Periplasmic binding protein 76 311 3.5E-25 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_1155 a2783c8f40bd9e136e21253cfdcce33e 340 Gene3D G3DSA:3.40.50.1980 166 339 1.9E-52 T 12-10-2018 NPD12_1155 a2783c8f40bd9e136e21253cfdcce33e 340 SUPERFAMILY SSF53807 63 340 1.26E-45 T 12-10-2018 NPD12_1155 a2783c8f40bd9e136e21253cfdcce33e 340 Gene3D G3DSA:3.40.50.1980 49 164 3.2E-35 T 12-10-2018 NPD12_2907 38b0a826894f770802e00ba0682eefdd 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 5.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_2907 38b0a826894f770802e00ba0682eefdd 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_2907 38b0a826894f770802e00ba0682eefdd 198 Gene3D G3DSA:1.10.357.10 55 198 2.2E-19 T 12-10-2018 NPD12_2907 38b0a826894f770802e00ba0682eefdd 198 Gene3D G3DSA:1.10.10.60 1 53 2.1E-16 T 12-10-2018 NPD12_2907 38b0a826894f770802e00ba0682eefdd 198 SUPERFAMILY SSF48498 121 194 8.9E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily NPD12_2907 38b0a826894f770802e00ba0682eefdd 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 4.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_2907 38b0a826894f770802e00ba0682eefdd 198 SUPERFAMILY SSF46689 7 65 1.85E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_539 2a5aa9f6110a27bc03cb633a629d257f 178 Gene3D G3DSA:1.10.1760.20 1 171 1.7E-17 T 12-10-2018 NPD12_539 2a5aa9f6110a27bc03cb633a629d257f 178 PIRSF PIRSF027391 3 178 2.2E-57 T 12-10-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I NPD12_539 2a5aa9f6110a27bc03cb633a629d257f 178 Pfam PF07456 Heptaprenyl diphosphate synthase component I 17 160 5.3E-49 T 12-10-2018 IPR010898 Heptaprenyl diphosphate synthase component I NPD12_718 a9e927985bf4006d319323d5a9345f31 149 SUPERFAMILY SSF55729 11 142 5.64E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_718 a9e927985bf4006d319323d5a9345f31 149 Pfam PF13508 Acetyltransferase (GNAT) domain 49 129 4.5E-13 T 12-10-2018 IPR000182 GNAT domain NPD12_718 a9e927985bf4006d319323d5a9345f31 149 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 28 112 0.004 T 12-10-2018 NPD12_718 a9e927985bf4006d319323d5a9345f31 149 Gene3D G3DSA:3.40.630.30 8 148 6.4E-19 T 12-10-2018 NPD12_905 57eefdeb31e2b34043cb47b0a84fac19 80 Pfam PF04994 TfoX C-terminal domain 21 72 4.9E-14 T 12-10-2018 IPR007077 TfoX, C-terminal NPD12_905 57eefdeb31e2b34043cb47b0a84fac19 80 Gene3D G3DSA:1.10.150.20 16 80 9.8E-21 T 12-10-2018 NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 SUPERFAMILY SSF54631 157 302 2.02E-32 T 12-10-2018 NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 Pfam PF03471 Transporter associated domain 299 377 4.0E-23 T 12-10-2018 IPR005170 Transporter-associated domain NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 Pfam PF01595 Domain of unknown function DUF21 2 147 1.9E-32 T 12-10-2018 IPR002550 CNNM, transmembrane domain NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 SMART SM00116 171 220 0.68 T 12-10-2018 IPR000644 CBS domain NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 SMART SM00116 235 283 24.0 T 12-10-2018 IPR000644 CBS domain NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 SUPERFAMILY SSF56176 296 376 1.39E-21 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 Gene3D G3DSA:3.30.465.10 296 378 5.4E-25 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 SMART SM01091 298 378 5.3E-25 T 12-10-2018 IPR005170 Transporter-associated domain NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 Gene3D G3DSA:3.10.580.10 141 294 3.4E-55 T 12-10-2018 NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 Pfam PF00571 CBS domain 164 216 0.0058 T 12-10-2018 IPR000644 CBS domain NPD12_2980 0af0d7c884cf245cdf05a8ff87b550cf 380 Pfam PF00571 CBS domain 235 283 0.0066 T 12-10-2018 IPR000644 CBS domain NPD12_1345 0f8556d716941ba17156ce702fe60fba 388 Gene3D G3DSA:1.20.58.1690 296 383 1.2E-19 T 12-10-2018 IPR038434 YARHG domain superfamily NPD12_1345 0f8556d716941ba17156ce702fe60fba 388 Pfam PF13308 YARHG domain 303 383 3.9E-25 T 12-10-2018 IPR025582 YARHG domain NPD12_1345 0f8556d716941ba17156ce702fe60fba 388 Pfam PF13240 zinc-ribbon domain 3 24 1.8E-7 T 12-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 NPD12_1345 0f8556d716941ba17156ce702fe60fba 388 SMART SM01324 302 386 1.0E-30 T 12-10-2018 IPR025582 YARHG domain NPD12_485 1c7ae918f36e39b4524a19e9b7209d7e 248 Pfam PF00005 ABC transporter 22 170 1.7E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_485 1c7ae918f36e39b4524a19e9b7209d7e 248 Gene3D G3DSA:3.40.50.300 1 240 9.2E-66 T 12-10-2018 NPD12_485 1c7ae918f36e39b4524a19e9b7209d7e 248 SMART SM00382 31 218 1.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_485 1c7ae918f36e39b4524a19e9b7209d7e 248 SUPERFAMILY SSF52540 3 225 2.72E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_717 6e42c84410b96c79b52b5bc910973776 67 Pfam PF01381 Helix-turn-helix 8 62 1.9E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_717 6e42c84410b96c79b52b5bc910973776 67 SMART SM00530 7 62 1.6E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_717 6e42c84410b96c79b52b5bc910973776 67 Gene3D G3DSA:1.10.260.40 3 67 3.1E-26 T 12-10-2018 NPD12_717 6e42c84410b96c79b52b5bc910973776 67 SUPERFAMILY SSF47413 4 66 3.49E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 SUPERFAMILY SSF50249 542 642 5.39E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Gene3D G3DSA:1.10.730.10 338 509 1.4E-51 T 12-10-2018 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Pfam PF09334 tRNA synthetases class I (M) 6 361 7.7E-117 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 SUPERFAMILY SSF47323 351 557 2.62E-46 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 506 50.858 T 12-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Gene3D G3DSA:2.170.220.10 117 226 2.1E-153 T 12-10-2018 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Pfam PF08264 Anticodon-binding domain of tRNA 385 537 2.5E-7 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 3.0E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 3.0E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 3.0E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.0E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 3.0E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.0E-34 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 508 9.7E-177 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Pfam PF01588 Putative tRNA binding domain 549 641 3.5E-28 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Gene3D G3DSA:2.40.50.140 533 644 3.6E-36 T 12-10-2018 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 511 644 9.1E-45 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 Gene3D G3DSA:3.40.50.620 6 334 2.1E-153 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_232 e31f5a46569ef3c0187aa815818785ba 645 SUPERFAMILY SSF52374 3 348 1.87E-118 T 12-10-2018 NPD12_1764 909a5767bf91094c2a7a359e92ac42b9 162 SUPERFAMILY SSF48695 29 152 1.88E-8 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily NPD12_1764 909a5767bf91094c2a7a359e92ac42b9 162 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 32 146 3.4E-23 T 12-10-2018 IPR010181 CGCAxxGCC motif NPD12_1764 909a5767bf91094c2a7a359e92ac42b9 162 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 32 151 7.2E-28 T 12-10-2018 IPR010181 CGCAxxGCC motif NPD12_2194 d9eb9a53c49d2b3f7d8f629ac6ccc2bc 166 SUPERFAMILY SSF55469 2 166 4.58E-48 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_2194 d9eb9a53c49d2b3f7d8f629ac6ccc2bc 166 Gene3D G3DSA:3.40.109.10 1 166 1.1E-52 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_2194 d9eb9a53c49d2b3f7d8f629ac6ccc2bc 166 Pfam PF00881 Nitroreductase family 62 145 9.0E-10 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_2194 d9eb9a53c49d2b3f7d8f629ac6ccc2bc 166 Pfam PF00881 Nitroreductase family 4 58 2.0E-16 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_640 15186375a90248bcf97db8a58a688279 182 Gene3D G3DSA:3.90.79.10 1 173 4.7E-41 T 12-10-2018 NPD12_640 15186375a90248bcf97db8a58a688279 182 SUPERFAMILY SSF55811 2 162 2.71E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 NPD12_640 15186375a90248bcf97db8a58a688279 182 Pfam PF00293 NUDIX domain 43 155 3.6E-7 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 NPD12_3506 f46bec24e9ec8c25c2b77ce67431aaee 437 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 427 3.0E-42 T 12-10-2018 IPR000160 GGDEF domain NPD12_3506 f46bec24e9ec8c25c2b77ce67431aaee 437 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 271 431 8.8E-43 T 12-10-2018 IPR000160 GGDEF domain NPD12_3506 f46bec24e9ec8c25c2b77ce67431aaee 437 Gene3D G3DSA:3.30.70.270 259 430 5.2E-45 T 12-10-2018 NPD12_3506 f46bec24e9ec8c25c2b77ce67431aaee 437 SUPERFAMILY SSF103190 45 230 3.37E-9 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_3506 f46bec24e9ec8c25c2b77ce67431aaee 437 SUPERFAMILY SSF55073 272 433 7.46E-40 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_3506 f46bec24e9ec8c25c2b77ce67431aaee 437 SMART SM00267 257 432 1.2E-42 T 12-10-2018 IPR000160 GGDEF domain NPD12_36 0239ec7463446080a5abe1216765e3ad 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 42.354 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_36 0239ec7463446080a5abe1216765e3ad 417 Gene3D G3DSA:3.65.10.10 20 231 1.7E-165 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 NPD12_36 0239ec7463446080a5abe1216765e3ad 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 5.6E-168 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 NPD12_36 0239ec7463446080a5abe1216765e3ad 417 SUPERFAMILY SSF55205 1 416 3.6E-134 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 NPD12_36 0239ec7463446080a5abe1216765e3ad 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 3.0E-96 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 NPD12_36 0239ec7463446080a5abe1216765e3ad 417 Gene3D G3DSA:3.65.10.10 6 414 1.7E-165 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 SUPERFAMILY SSF53335 139 442 6.43E-71 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 Pfam PF01029 NusB family 3 126 7.5E-32 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 Gene3D G3DSA:3.40.50.150 144 441 4.7E-82 T 12-10-2018 NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 SUPERFAMILY SSF48013 3 153 1.96E-34 T 12-10-2018 IPR035926 NusB-like superfamily NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 247 440 1.0E-58 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 256 266 2.3E-26 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 2.3E-26 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 2.3E-26 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 2.3E-26 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 424 441 2.3E-26 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 5 441 5.5E-123 T 12-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 NPD12_2554 6bebfd7628e7d9df2b660bad3900b16e 442 Gene3D G3DSA:1.10.940.10 1 142 3.2E-38 T 12-10-2018 IPR035926 NusB-like superfamily NPD12_607 0392439c6840c3f97824a74fa6b46223 563 Pfam PF02743 Cache domain 423 559 9.0E-14 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 Gene3D G3DSA:1.10.287.950 128 431 4.9E-62 T 12-10-2018 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 194 375 9.6E-38 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 SMART SM00283 156 417 1.3E-57 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 283 312 1.3E-11 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 184 213 1.3E-11 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 331 360 1.3E-11 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 SUPERFAMILY SSF103190 463 549 3.53E-11 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_607 0392439c6840c3f97824a74fa6b46223 563 Gene3D G3DSA:3.30.450.20 464 559 5.0E-20 T 12-10-2018 NPD12_607 0392439c6840c3f97824a74fa6b46223 563 SUPERFAMILY SSF58104 162 430 1.05E-61 T 12-10-2018 NPD12_1778 74d87a6a1b246b4b3e0278974eb214ee 124 SUPERFAMILY SSF81665 4 120 4.45E-10 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 NPD12_1778 74d87a6a1b246b4b3e0278974eb214ee 124 Pfam PF00689 Cation transporting ATPase, C-terminus 1 115 4.0E-9 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 NPD12_1778 74d87a6a1b246b4b3e0278974eb214ee 124 Gene3D G3DSA:1.20.1110.10 6 121 4.4E-6 T 12-10-2018 NPD12_3174 701b82b22ddb16b5e2b9a82b8009563f 45 TIGRFAM TIGR03973 six_Cys_in_45: six-cysteine peptide SCIFF 2 44 2.1E-23 T 12-10-2018 IPR023975 Six-cysteine peptide SCIFF NPD12_3174 701b82b22ddb16b5e2b9a82b8009563f 45 Pfam PF13165 Six-cysteine peptide SCIFF 2 45 8.3E-22 T 12-10-2018 IPR023975 Six-cysteine peptide SCIFF NPD12_2857 6eaf385831f82ab5d0178a15d002628a 145 SUPERFAMILY SSF55811 8 137 1.1E-33 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 NPD12_2857 6eaf385831f82ab5d0178a15d002628a 145 Gene3D G3DSA:3.90.79.10 2 140 1.2E-35 T 12-10-2018 NPD12_2857 6eaf385831f82ab5d0178a15d002628a 145 Pfam PF00293 NUDIX domain 9 133 1.4E-25 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 NPD12_2857 6eaf385831f82ab5d0178a15d002628a 145 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 NPD12_2857 6eaf385831f82ab5d0178a15d002628a 145 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_2857 6eaf385831f82ab5d0178a15d002628a 145 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 Gene3D G3DSA:1.20.120.610 6 158 4.7E-50 T 12-10-2018 NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 Pfam PF00137 ATP synthase subunit C 97 156 1.1E-13 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 Pfam PF00137 ATP synthase subunit C 21 79 1.0E-13 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 SUPERFAMILY SSF81333 90 157 3.4E-12 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 SUPERFAMILY SSF81333 18 80 9.81E-10 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 135 158 1.4E-7 T 12-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 60 84 1.4E-7 T 12-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2677 e58adc81cdd8f55ffefbcf4471452a81 158 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 34 58 1.4E-7 T 12-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2966 d9657a0fede0df0609a2cd9d74ad46f6 229 Pfam PF13346 ABC-2 family transporter protein 6 220 7.1E-19 T 12-10-2018 IPR025699 ABC-2 membrane transporter-like NPD12_778 6808a0acb5983db56d9f31898df74140 151 Gene3D G3DSA:2.40.50.1020 38 142 8.2E-13 T 12-10-2018 NPD12_778 6808a0acb5983db56d9f31898df74140 151 Pfam PF04397 LytTr DNA-binding domain 54 144 6.1E-18 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_778 6808a0acb5983db56d9f31898df74140 151 SMART SM00850 50 147 1.6E-23 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 NPD12_3074 58e3bbc29bd95d85e218ca9f733e119a 86 Gene3D G3DSA:1.10.1660.40 28 74 9.7E-7 T 12-10-2018 IPR038148 Transposon Tn1545/Tn916, excisionase NPD12_3074 58e3bbc29bd95d85e218ca9f733e119a 86 Pfam PF12728 Helix-turn-helix domain 29 78 1.8E-6 T 12-10-2018 NPD12_3074 58e3bbc29bd95d85e218ca9f733e119a 86 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 28 78 2.2E-11 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 NPD12_2188 7593f753ce93e15bccd6f8965ed99b24 448 SUPERFAMILY SSF103473 8 429 3.27E-37 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_2188 7593f753ce93e15bccd6f8965ed99b24 448 Gene3D G3DSA:1.20.1250.20 2 217 7.6E-42 T 12-10-2018 NPD12_2188 7593f753ce93e15bccd6f8965ed99b24 448 Pfam PF07690 Major Facilitator Superfamily 25 392 1.2E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_2188 7593f753ce93e15bccd6f8965ed99b24 448 Gene3D G3DSA:1.20.1250.20 218 437 7.7E-34 T 12-10-2018 NPD12_1292 3f3006ef4e205658b5028e914e3c7724 214 SMART SM00471 63 198 5.3E-4 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_1292 3f3006ef4e205658b5028e914e3c7724 214 SUPERFAMILY SSF109604 29 206 1.33E-18 T 12-10-2018 NPD12_1292 3f3006ef4e205658b5028e914e3c7724 214 Pfam PF01966 HD domain 68 186 5.6E-10 T 12-10-2018 IPR006674 HD domain NPD12_1292 3f3006ef4e205658b5028e914e3c7724 214 TIGRFAM TIGR00277 HDIG: HDIG domain 66 124 4.5E-8 T 12-10-2018 IPR006675 HDIG domain NPD12_1292 3f3006ef4e205658b5028e914e3c7724 214 Gene3D G3DSA:1.10.3210.10 48 213 1.4E-11 T 12-10-2018 NPD12_1788 2843372631a84693cde578fdb63cdff0 160 SUPERFAMILY SSF46785 80 156 3.48E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1788 2843372631a84693cde578fdb63cdff0 160 Pfam PF13545 Crp-like helix-turn-helix domain 83 153 8.0E-9 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 NPD12_1788 2843372631a84693cde578fdb63cdff0 160 Gene3D G3DSA:2.60.120.1460 1 156 7.0E-15 T 12-10-2018 NPD12_1788 2843372631a84693cde578fdb63cdff0 160 SUPERFAMILY SSF51206 2 68 4.01E-9 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like NPD12_3397 72b37f0cd5e062bb331d609e006ad7ea 403 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.7E-7 T 12-10-2018 NPD12_3397 72b37f0cd5e062bb331d609e006ad7ea 403 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 1.7E-7 T 12-10-2018 NPD12_3397 72b37f0cd5e062bb331d609e006ad7ea 403 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.7E-7 T 12-10-2018 NPD12_3397 72b37f0cd5e062bb331d609e006ad7ea 403 PRINTS PR00173 Glutamate-aspartate symporter signature 273 299 1.7E-7 T 12-10-2018 NPD12_3397 72b37f0cd5e062bb331d609e006ad7ea 403 SUPERFAMILY SSF118215 6 381 1.44E-78 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_3397 72b37f0cd5e062bb331d609e006ad7ea 403 Gene3D G3DSA:1.10.3860.10 1 385 9.8E-51 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_3397 72b37f0cd5e062bb331d609e006ad7ea 403 Pfam PF00375 Sodium:dicarboxylate symporter family 6 381 5.3E-73 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 NPD12_936 54a272572854c94267f22f9b69bf0f6b 138 SMART SM00226 3 128 1.8E-16 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I NPD12_936 54a272572854c94267f22f9b69bf0f6b 138 SUPERFAMILY SSF52788 1 127 1.57E-28 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily NPD12_936 54a272572854c94267f22f9b69bf0f6b 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 125 4.6E-13 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I NPD12_936 54a272572854c94267f22f9b69bf0f6b 138 Gene3D G3DSA:3.40.50.2300 2 134 8.4E-33 T 12-10-2018 NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 SMART SM00866 84 223 1.7E-29 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 Gene3D G3DSA:1.10.10.10 1 72 4.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 Gene3D G3DSA:3.40.1410.10 82 222 9.3E-34 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 22 36 5.1E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 52 5.1E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 62 8.8E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 SUPERFAMILY SSF46785 3 67 1.21E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 SMART SM00345 3 62 1.9E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 SUPERFAMILY SSF64288 68 227 2.67E-43 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 2 230 1.8E-89 T 12-10-2018 IPR012770 Trehalose operon transcriptional repressor NPD12_2151 d7e7349a52359f950dd20dddb0551b19 231 Pfam PF07702 UTRA domain 85 223 3.5E-33 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 NPD12_1254 8078671cf5566a4c8908cd33dc10295e 233 Pfam PF02517 CAAX protease self-immunity 121 220 5.2E-14 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 SUPERFAMILY SSF55347 153 315 1.73E-75 T 12-10-2018 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 326 2.9E-141 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 PIRSF PIRSF000149 1 335 1.1E-140 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 3.1E-72 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 SUPERFAMILY SSF51735 2 169 1.39E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_384 b780694e970a6b1208edd7353eab7c72 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 103 2.6E-39 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.3E-40 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.3E-40 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.3E-40 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.3E-40 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.3E-40 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 Gene3D G3DSA:3.40.50.720 3 329 3.6E-158 T 12-10-2018 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 Gene3D G3DSA:3.30.360.10 152 316 3.6E-158 T 12-10-2018 NPD12_384 b780694e970a6b1208edd7353eab7c72 335 SMART SM00846 2 153 2.4E-95 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 Hamap MF_00242 Arginine deiminase [arcA]. 2 407 44.925 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 PIRSF PIRSF006356 1 407 4.4E-163 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 TIGRFAM TIGR01078 arcA: arginine deiminase 5 406 2.7E-165 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 Gene3D G3DSA:1.10.3930.10 69 152 1.0E-161 T 12-10-2018 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 Pfam PF02274 Amidinotransferase 19 404 8.5E-103 T 12-10-2018 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 SUPERFAMILY SSF55909 2 407 9.49E-127 T 12-10-2018 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 Gene3D G3DSA:3.75.10.10 6 402 1.0E-161 T 12-10-2018 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 4.9E-54 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 4.9E-54 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 4.9E-54 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 4.9E-54 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 PRINTS PR01466 Bacterial arginine deiminase signature 180 195 4.9E-54 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1827 6bcc24497b51de32685bc8145f5658be 408 PRINTS PR01466 Bacterial arginine deiminase signature 152 170 4.9E-54 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 NPD12_1617 bc47ada598df7fae14e249c0021d61aa 412 Pfam PF04122 Putative cell wall binding repeat 2 64 158 4.2E-6 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_1472 f8d619ec8e4154c34d1661ed4fd25533 564 SUPERFAMILY SSF56672 223 563 1.22E-39 T 12-10-2018 NPD12_1472 f8d619ec8e4154c34d1661ed4fd25533 564 Gene3D G3DSA:3.90.1600.10 263 447 2.1E-8 T 12-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 NPD12_1970 3c8bcc4dec3b1ac09303242b3f42029d 143 Pfam PF00085 Thioredoxin 46 139 1.4E-17 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 NPD12_1970 3c8bcc4dec3b1ac09303242b3f42029d 143 SUPERFAMILY SSF52833 48 140 7.93E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_1970 3c8bcc4dec3b1ac09303242b3f42029d 143 ProSitePatterns PS00194 Thioredoxin family active site. 57 75 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 NPD12_1970 3c8bcc4dec3b1ac09303242b3f42029d 143 Gene3D G3DSA:3.40.30.10 31 143 3.9E-26 T 12-10-2018 NPD12_3583 6c7fd1f598b1ae17f0be5774e27ad375 220 SUPERFAMILY SSF52540 3 153 2.15E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3583 6c7fd1f598b1ae17f0be5774e27ad375 220 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 12 126 6.4E-7 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain NPD12_3583 6c7fd1f598b1ae17f0be5774e27ad375 220 Gene3D G3DSA:3.40.50.300 1 123 6.4E-9 T 12-10-2018 NPD12_2995 eea0b6c83adecbecc1c1c014b17ee658 132 SUPERFAMILY SSF53927 1 130 7.68E-48 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_2995 eea0b6c83adecbecc1c1c014b17ee658 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 NPD12_2995 eea0b6c83adecbecc1c1c014b17ee658 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 98 8.6E-18 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain NPD12_2995 eea0b6c83adecbecc1c1c014b17ee658 132 Gene3D G3DSA:3.40.140.10 1 132 7.4E-55 T 12-10-2018 NPD12_2995 eea0b6c83adecbecc1c1c014b17ee658 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 4 130 3.4E-48 T 12-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 NPD12_3309 15d89068db4cd835c68637ff8dab2ab0 259 PIRSF PIRSF000090 1 259 5.2E-99 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 NPD12_3309 15d89068db4cd835c68637ff8dab2ab0 259 Pfam PF01012 Electron transfer flavoprotein domain 23 206 1.1E-53 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3309 15d89068db4cd835c68637ff8dab2ab0 259 Gene3D G3DSA:3.40.50.620 1 258 1.4E-98 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_3309 15d89068db4cd835c68637ff8dab2ab0 259 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 NPD12_3309 15d89068db4cd835c68637ff8dab2ab0 259 SMART SM00893 22 211 1.8E-67 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 NPD12_3309 15d89068db4cd835c68637ff8dab2ab0 259 SUPERFAMILY SSF52402 1 251 2.37E-83 T 12-10-2018 NPD12_2023 610012447f9eaa773b43b4fa43538ea0 252 SUPERFAMILY SSF54001 27 140 1.8E-43 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_2023 610012447f9eaa773b43b4fa43538ea0 252 Gene3D G3DSA:3.90.1720.10 20 142 4.9E-50 T 12-10-2018 NPD12_2023 610012447f9eaa773b43b4fa43538ea0 252 Pfam PF00877 NlpC/P60 family 43 138 4.7E-29 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 SUPERFAMILY SSF52540 8 141 4.2E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 SUPERFAMILY SSF57716 142 190 3.99E-16 T 12-10-2018 NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 Gene3D G3DSA:3.40.50.300 1 141 1.9E-59 T 12-10-2018 NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 Pfam PF00265 Thymidine kinase 8 187 8.1E-60 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.8 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 Gene3D G3DSA:3.30.60.20 142 191 1.7E-24 T 12-10-2018 NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 12-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 NPD12_290 faa029cd4cc2b75a7262193e2873ce63 191 PIRSF PIRSF035805 5 191 5.8E-69 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 34 463 3.6E-90 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 Gene3D G3DSA:3.40.630.10 45 455 3.8E-152 T 12-10-2018 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 292 310 7.4E-29 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 132 152 7.4E-29 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 431 446 7.4E-29 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 337 353 7.4E-29 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 99 115 7.4E-29 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 168 185 7.4E-29 T 12-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 SUPERFAMILY SSF53187 12 464 3.46E-105 T 12-10-2018 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 SUPERFAMILY SSF101821 111 243 3.02E-36 T 12-10-2018 NPD12_2651 61132a9605306fb86464ad3ad4a21b7c 467 Gene3D G3DSA:2.30.250.10 110 247 3.8E-152 T 12-10-2018 IPR023358 Peptidase M18, domain 2 GO:0004177 NPD12_1392 b0faf0736fe86932a9097495a322a8af 290 SMART SM00382 28 206 4.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1392 b0faf0736fe86932a9097495a322a8af 290 Gene3D G3DSA:3.40.50.300 1 226 2.4E-43 T 12-10-2018 NPD12_1392 b0faf0736fe86932a9097495a322a8af 290 Pfam PF00005 ABC transporter 19 156 1.9E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1392 b0faf0736fe86932a9097495a322a8af 290 SUPERFAMILY SSF52540 4 218 6.61E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 Gene3D G3DSA:1.10.10.10 4 146 9.6E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 95 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 Pfam PF01047 MarR family 31 86 3.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 SMART SM00347 22 122 1.8E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2363 07a8c82b4ddbfe02ff59c52740f78ae8 154 SUPERFAMILY SSF46785 7 141 1.32E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3419 5d84d751728d21f35d91776fb25d3c15 264 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 5 253 3.1E-80 T 12-10-2018 IPR008275 CoA enzyme activase NPD12_3419 5d84d751728d21f35d91776fb25d3c15 264 Gene3D G3DSA:3.30.420.40 7 255 7.5E-84 T 12-10-2018 NPD12_3419 5d84d751728d21f35d91776fb25d3c15 264 SUPERFAMILY SSF53067 5 258 1.49E-39 T 12-10-2018 NPD12_3419 5d84d751728d21f35d91776fb25d3c15 264 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 8 255 1.0E-63 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_3419 5d84d751728d21f35d91776fb25d3c15 264 Gene3D G3DSA:3.30.420.40 98 238 7.5E-84 T 12-10-2018 NPD12_2683 6236edf618593afd12fffa6396591172 399 Pfam PF07995 Glucose / Sorbosone dehydrogenase 218 290 1.8E-5 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase NPD12_2683 6236edf618593afd12fffa6396591172 399 SUPERFAMILY SSF50952 54 290 8.11E-18 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 NPD12_2683 6236edf618593afd12fffa6396591172 399 Gene3D G3DSA:2.120.10.30 90 398 9.8E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like NPD12_1081 f092d01f87fa7fc274d86e5d87828965 102 Pfam PF12788 YmaF family 8 102 7.2E-38 T 12-10-2018 IPR024307 YmaF NPD12_1300 6d4fb04bc26ec8cb363917ba0b2fce22 412 Gene3D G3DSA:3.40.190.10 169 338 4.8E-8 T 12-10-2018 NPD12_1300 6d4fb04bc26ec8cb363917ba0b2fce22 412 SUPERFAMILY SSF53850 46 365 4.69E-36 T 12-10-2018 NPD12_1300 6d4fb04bc26ec8cb363917ba0b2fce22 412 PIRSF PIRSF029172 1 411 5.5E-180 T 12-10-2018 IPR027020 Protein ynjB NPD12_1300 6d4fb04bc26ec8cb363917ba0b2fce22 412 Gene3D G3DSA:3.40.190.10 45 168 3.3E-9 T 12-10-2018 NPD12_1300 6d4fb04bc26ec8cb363917ba0b2fce22 412 Pfam PF13416 Bacterial extracellular solute-binding protein 68 366 5.6E-35 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 Pfam PF13394 4Fe-4S single cluster domain 17 106 1.5E-7 T 12-10-2018 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 1 319 9.6E-113 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 SUPERFAMILY SSF102114 3 279 8.76E-73 T 12-10-2018 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 SMART SM00729 10 214 1.2E-10 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 Pfam PF06463 Molybdenum Cofactor Synthesis C 181 301 1.4E-31 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 16 27 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 Pfam PF04055 Radical SAM superfamily 14 175 2.7E-31 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 1 319 37.02 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2106 c8cff736f5a7f9a0087dee3570e979a8 319 Gene3D G3DSA:3.20.20.70 1 319 4.0E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3814 ca15ad7999da4e8354ff66cb6c30b4e9 618 Gene3D G3DSA:3.40.1360.10 183 302 8.3E-17 T 12-10-2018 NPD12_3814 ca15ad7999da4e8354ff66cb6c30b4e9 618 Gene3D G3DSA:3.40.50.300 317 593 1.2E-35 T 12-10-2018 NPD12_3814 ca15ad7999da4e8354ff66cb6c30b4e9 618 Pfam PF13155 Toprim-like 199 284 7.0E-6 T 12-10-2018 NPD12_3814 ca15ad7999da4e8354ff66cb6c30b4e9 618 SUPERFAMILY SSF52540 321 575 8.46E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3814 ca15ad7999da4e8354ff66cb6c30b4e9 618 Pfam PF13481 AAA domain 327 513 4.7E-8 T 12-10-2018 NPD12_3814 ca15ad7999da4e8354ff66cb6c30b4e9 618 SUPERFAMILY SSF56731 112 286 5.75E-16 T 12-10-2018 NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 SUPERFAMILY SSF53187 754 961 2.07E-46 T 12-10-2018 NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Pfam PF07495 Y_Y_Y domain 475 538 9.7E-8 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Pfam PF07495 Y_Y_Y domain 371 432 2.1E-8 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Pfam PF07495 Y_Y_Y domain 267 329 2.2E-7 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Pfam PF07495 Y_Y_Y domain 579 644 5.3E-8 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Pfam PF07495 Y_Y_Y domain 686 740 4.9E-8 T 12-10-2018 IPR011123 Two component regulator three Y NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 SMART SM00646 825 958 2.4E-27 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 756 958 1.2E-46 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 86 216 1.7E-11 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 NPD12_3219 5a058a261b61cc7a9cd616ae927a3822 963 Gene3D G3DSA:3.40.630.40 747 963 8.7E-52 T 12-10-2018 NPD12_2430 25494adb4faa22d925735fa50e1a6017 169 Pfam PF13655 N-terminal domain of reverse transcriptase 7 60 1.9E-16 T 12-10-2018 IPR025960 Reverse transcriptase, N-terminal domain NPD12_2430 25494adb4faa22d925735fa50e1a6017 169 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 80 149 1.6E-11 T 12-10-2018 IPR000477 Reverse transcriptase domain NPD12_2430 25494adb4faa22d925735fa50e1a6017 169 SUPERFAMILY SSF56672 53 151 7.23E-15 T 12-10-2018 NPD12_412 22eb2eb9615bfb7e4879eef547a21533 487 PIRSF PIRSF006060 1 480 8.9E-85 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_412 22eb2eb9615bfb7e4879eef547a21533 487 Pfam PF00324 Amino acid permease 22 467 1.7E-133 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 NPD12_412 22eb2eb9615bfb7e4879eef547a21533 487 Gene3D G3DSA:1.20.1740.10 12 480 3.7E-64 T 12-10-2018 NPD12_987 8b47cbb06538222e7fbff06cfa98944f 344 SUPERFAMILY SSF64518 3 342 6.67E-13 T 12-10-2018 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 Pfam PF04545 Sigma-70, region 4 176 229 8.9E-16 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 55 230 1.1E-33 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 82 95 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 201 227 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 Gene3D G3DSA:1.10.10.10 158 234 2.8E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 Pfam PF04542 Sigma-70 region 2 58 127 2.7E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 Gene3D G3DSA:1.20.120.1810 28 127 6.6E-24 T 12-10-2018 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 PIRSF PIRSF000770 8 235 2.3E-69 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 SUPERFAMILY SSF88659 139 233 3.74E-23 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 SUPERFAMILY SSF88946 25 127 3.3E-34 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 PRINTS PR00046 Major sigma-70 factor signature 201 216 1.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 PRINTS PR00046 Major sigma-70 factor signature 216 227 1.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 PRINTS PR00046 Major sigma-70 factor signature 82 95 1.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 PRINTS PR00046 Major sigma-70 factor signature 180 192 1.9E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 NPD12_2580 1392bfe7767e3ab5c90222754272e72d 235 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 3 235 2.8E-127 T 12-10-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_1539 3c350028a7c5ed381850ee9a101f6b8e 201 SUPERFAMILY SSF103473 4 199 8.63E-5 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_1539 3c350028a7c5ed381850ee9a101f6b8e 201 Pfam PF02659 Putative manganese efflux pump 31 190 2.2E-54 T 12-10-2018 IPR003810 Putative manganese efflux pump NPD12_1539 3c350028a7c5ed381850ee9a101f6b8e 201 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 193 25.885 T 12-10-2018 IPR022929 Putative manganese efflux pump MntP NPD12_2738 010e86a8b6c7cfe505ac65ba8e3575d1 320 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 77 234 6.6E-44 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain NPD12_2738 010e86a8b6c7cfe505ac65ba8e3575d1 320 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 234 3.7E-33 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain NPD12_2738 010e86a8b6c7cfe505ac65ba8e3575d1 320 Gene3D G3DSA:1.10.260.150 55 319 6.2E-75 T 12-10-2018 NPD12_1068 e6e7d12cae8c3d00f42cd9bc87b5663c 251 Gene3D G3DSA:3.60.60.10 1 229 3.7E-35 T 12-10-2018 NPD12_1068 e6e7d12cae8c3d00f42cd9bc87b5663c 251 SUPERFAMILY SSF56235 9 117 6.94E-13 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_1068 e6e7d12cae8c3d00f42cd9bc87b5663c 251 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 4 215 2.4E-33 T 12-10-2018 IPR005079 Peptidase C45 NPD12_2674 a188bd1eabf82e73c53b36797adf804b 102 SUPERFAMILY SSF159468 4 101 4.45E-26 T 12-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2674 a188bd1eabf82e73c53b36797adf804b 102 Gene3D G3DSA:3.40.50.10580 1 102 3.0E-30 T 12-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2674 a188bd1eabf82e73c53b36797adf804b 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 4 93 1.0E-23 T 12-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2674 a188bd1eabf82e73c53b36797adf804b 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 2 102 16.907 T 12-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal NPD12_338 3ba7b761542060950649368ad1385502 228 SUPERFAMILY SSF56300 3 218 2.17E-27 T 12-10-2018 NPD12_338 3ba7b761542060950649368ad1385502 228 Pfam PF00149 Calcineurin-like phosphoesterase 4 195 1.1E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 NPD12_338 3ba7b761542060950649368ad1385502 228 PIRSF PIRSF033094 1 228 2.8E-99 T 12-10-2018 IPR014578 Predicted phosphoesterase, CT488 type NPD12_847 3c06a4efa8dec30ed54705e4c8f7f92f 126 Gene3D G3DSA:1.10.4040.10 72 122 1.3E-17 T 12-10-2018 NPD12_847 3c06a4efa8dec30ed54705e4c8f7f92f 126 SUPERFAMILY SSF46785 4 124 1.09E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_847 3c06a4efa8dec30ed54705e4c8f7f92f 126 Gene3D G3DSA:1.10.10.10 8 71 3.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_847 3c06a4efa8dec30ed54705e4c8f7f92f 126 PIRSF PIRSF019455 1 126 2.7E-40 T 12-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 NPD12_847 3c06a4efa8dec30ed54705e4c8f7f92f 126 Pfam PF03965 Penicillinase repressor 7 120 4.5E-35 T 12-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 NPD12_2881 34bf52e9ffefbc53b18f2338eca329d5 124 Pfam PF06115 Domain of unknown function (DUF956) 1 116 4.5E-57 T 12-10-2018 IPR010360 Protein of unknown function DUF956 NPD12_2881 34bf52e9ffefbc53b18f2338eca329d5 124 PIRSF PIRSF021265 1 123 5.5E-57 T 12-10-2018 IPR010360 Protein of unknown function DUF956 NPD12_2435 697f7f97e628798fec6d2529fe184db5 54 SUPERFAMILY SSF50044 9 51 7.48E-5 T 12-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 NPD12_407 a19319e98ad961da4e3c2fd0d41574f1 306 SUPERFAMILY SSF52540 3 228 4.65E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_407 a19319e98ad961da4e3c2fd0d41574f1 306 Gene3D G3DSA:3.40.50.300 1 238 1.6E-56 T 12-10-2018 NPD12_407 a19319e98ad961da4e3c2fd0d41574f1 306 SMART SM00382 30 214 8.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_407 a19319e98ad961da4e3c2fd0d41574f1 306 Pfam PF00005 ABC transporter 21 162 8.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_407 a19319e98ad961da4e3c2fd0d41574f1 306 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1785 3c30a86caf4aaf40218931c1bb959c5b 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 115 1.6E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain NPD12_1785 3c30a86caf4aaf40218931c1bb959c5b 120 Gene3D G3DSA:3.10.180.10 6 119 1.2E-14 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_1785 3c30a86caf4aaf40218931c1bb959c5b 120 SUPERFAMILY SSF54593 11 119 1.61E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 Pfam PF02607 B12 binding domain 9 82 1.2E-17 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 SMART SM01018 6 89 1.1E-32 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 Gene3D G3DSA:1.10.1240.10 4 84 1.2E-29 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 SUPERFAMILY SSF47644 6 88 4.97E-24 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 Gene3D G3DSA:3.40.50.280 85 219 2.1E-50 T 12-10-2018 NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 TIGRFAM TIGR02370 pyl_corrinoid: methyltransferase cognate corrinoid proteins, Methanosarcina family 11 206 2.2E-65 T 12-10-2018 IPR012741 Methyltransferase cognate corrinoid protein GO:0015948|GO:0031419|GO:0050897 NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 SUPERFAMILY SSF52242 74 217 1.18E-48 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 NPD12_1743 c4a05800bc53c0dfa926fd2fc120111c 220 Pfam PF02310 B12 binding domain 95 199 3.8E-24 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 Gene3D G3DSA:1.20.1330.10 48 224 2.6E-65 T 12-10-2018 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 PRINTS PR00207 Flagellin signature 109 132 2.1E-25 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 PRINTS PR00207 Flagellin signature 35 52 2.1E-25 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 PRINTS PR00207 Flagellin signature 74 93 2.1E-25 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 SUPERFAMILY SSF64518 1 273 3.14E-93 T 12-10-2018 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 Gene3D G3DSA:1.10.8.410 225 273 5.7E-29 T 12-10-2018 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 2.7E-41 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2764 d64ab27571a38264ee3773dd29b60829 273 Pfam PF00700 Bacterial flagellin C-terminal helical region 187 272 2.2E-30 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2846 18b8f6c327e87f8cae405fe59144989f 283 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 173 239 1.2E-17 T 12-10-2018 IPR039561 Peptidase M15C GO:0008233 NPD12_2846 18b8f6c327e87f8cae405fe59144989f 283 SUPERFAMILY SSF55166 162 246 2.3E-17 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_2846 18b8f6c327e87f8cae405fe59144989f 283 Gene3D G3DSA:3.30.1380.10 109 238 5.1E-13 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_884 0a2e58bdf6c14e2c84cfd70090a0a398 600 Pfam PF02687 FtsX-like permease family 104 201 4.0E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_884 0a2e58bdf6c14e2c84cfd70090a0a398 600 Pfam PF02687 FtsX-like permease family 500 591 4.2E-16 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 Gene3D G3DSA:3.40.50.150 5 306 9.8E-111 T 12-10-2018 NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 SUPERFAMILY SSF53335 5 308 5.76E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 309 39.709 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 Pfam PF01795 MraW methylase family 2 309 2.6E-131 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 Gene3D G3DSA:1.10.150.170 111 214 9.8E-111 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 308 1.4E-125 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 SUPERFAMILY SSF81799 113 213 1.83E-37 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 NPD12_1704 4f09fc2dc2f27567a2e80968bfd55c9f 309 PIRSF PIRSF004486 1 309 7.1E-118 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 NPD12_1485 375fc45de0ddaf47661a10dc4ad49974 469 Pfam PF03237 Terminase-like family 59 224 2.2E-5 T 12-10-2018 IPR004921 Terminase large subunit, T4likevirus-type NPD12_1485 375fc45de0ddaf47661a10dc4ad49974 469 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 319 460 1.1E-34 T 12-10-2018 IPR006517 Archaeophage PsiM2, terminase large subunit NPD12_1485 375fc45de0ddaf47661a10dc4ad49974 469 Pfam PF17289 Terminase RNaseH-like domain 310 454 4.4E-6 T 12-10-2018 IPR035421 Terminase, large subunit gp17-like NPD12_1485 375fc45de0ddaf47661a10dc4ad49974 469 Gene3D G3DSA:3.40.50.300 7 225 7.5E-6 T 12-10-2018 NPD12_376 c2475d661a5e7ac0fdfb072d78cf2664 279 SUPERFAMILY SSF82549 3 278 8.89E-87 T 12-10-2018 NPD12_376 c2475d661a5e7ac0fdfb072d78cf2664 279 Gene3D G3DSA:3.40.50.10170 2 151 5.1E-57 T 12-10-2018 NPD12_376 c2475d661a5e7ac0fdfb072d78cf2664 279 Gene3D G3DSA:3.30.1180.10 154 279 2.1E-31 T 12-10-2018 NPD12_376 c2475d661a5e7ac0fdfb072d78cf2664 279 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 276 8.2E-97 T 12-10-2018 IPR003797 DegV NPD12_376 c2475d661a5e7ac0fdfb072d78cf2664 279 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 277 3.2E-95 T 12-10-2018 IPR003797 DegV NPD12_990 a309749e18028a1a24bed76f034d8c38 146 PIRSF PIRSF037660 1 146 1.8E-83 T 12-10-2018 IPR008903 Hemagglutinin component HA-17 NPD12_990 a309749e18028a1a24bed76f034d8c38 146 SUPERFAMILY SSF50370 4 146 5.04E-14 T 12-10-2018 IPR035992 Ricin B-like lectins NPD12_990 a309749e18028a1a24bed76f034d8c38 146 Gene3D G3DSA:2.80.10.50 1 146 4.8E-58 T 12-10-2018 NPD12_990 a309749e18028a1a24bed76f034d8c38 146 Pfam PF05588 Clostridium botulinum HA-17 domain 1 146 1.3E-82 T 12-10-2018 NPD12_3494 c81df300fa169d54c09a0aa82b9d2cf8 230 Gene3D G3DSA:1.10.10.10 130 230 7.1E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3494 c81df300fa169d54c09a0aa82b9d2cf8 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 5.6E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_3494 c81df300fa169d54c09a0aa82b9d2cf8 230 SMART SM00862 150 226 1.6E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_3494 c81df300fa169d54c09a0aa82b9d2cf8 230 SMART SM00448 3 113 4.4E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_3494 c81df300fa169d54c09a0aa82b9d2cf8 230 SUPERFAMILY SSF52172 3 184 4.25E-40 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_3494 c81df300fa169d54c09a0aa82b9d2cf8 230 Gene3D G3DSA:3.40.50.2300 1 129 6.0E-39 T 12-10-2018 NPD12_3494 c81df300fa169d54c09a0aa82b9d2cf8 230 Pfam PF00072 Response regulator receiver domain 5 112 1.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1607 d2e5b201e6041ad12b21a16642a1d640 253 SUPERFAMILY SSF52540 3 229 4.93E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1607 d2e5b201e6041ad12b21a16642a1d640 253 Gene3D G3DSA:3.40.50.300 2 253 3.3E-63 T 12-10-2018 NPD12_1607 d2e5b201e6041ad12b21a16642a1d640 253 SMART SM00382 28 216 3.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1607 d2e5b201e6041ad12b21a16642a1d640 253 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1607 d2e5b201e6041ad12b21a16642a1d640 253 Pfam PF00005 ABC transporter 19 167 2.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_603 1cc6e75845e908ecf7e8e1e88133ddb8 113 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 18.602 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 NPD12_603 1cc6e75845e908ecf7e8e1e88133ddb8 113 PIRSF PIRSF004761 1 113 1.1E-24 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 NPD12_603 1cc6e75845e908ecf7e8e1e88133ddb8 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 2 110 2.9E-25 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 NPD12_603 1cc6e75845e908ecf7e8e1e88133ddb8 113 Gene3D G3DSA:3.30.2320.80 1 112 7.8E-25 T 12-10-2018 NPD12_2800 ef5960d353579f808eb45ee334e6a151 402 SUPERFAMILY SSF63411 2 210 5.33E-48 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_2800 ef5960d353579f808eb45ee334e6a151 402 Pfam PF05193 Peptidase M16 inactive domain 161 336 8.3E-29 T 12-10-2018 IPR007863 Peptidase M16, C-terminal NPD12_2800 ef5960d353579f808eb45ee334e6a151 402 Gene3D G3DSA:3.30.830.10 216 401 1.1E-22 T 12-10-2018 NPD12_2800 ef5960d353579f808eb45ee334e6a151 402 Gene3D G3DSA:3.30.830.10 1 210 1.6E-50 T 12-10-2018 NPD12_2800 ef5960d353579f808eb45ee334e6a151 402 SUPERFAMILY SSF63411 222 398 2.17E-23 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 NPD12_2800 ef5960d353579f808eb45ee334e6a151 402 Pfam PF00675 Insulinase (Peptidase family M16) 9 150 2.9E-22 T 12-10-2018 IPR011765 Peptidase M16, N-terminal NPD12_2549 4d59b4be29b38fcc663bab4229c1a585 216 SUPERFAMILY SSF51366 1 214 1.26E-73 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 NPD12_2549 4d59b4be29b38fcc663bab4229c1a585 216 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 NPD12_2549 4d59b4be29b38fcc663bab4229c1a585 216 Gene3D G3DSA:3.20.20.70 1 216 8.4E-87 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2549 4d59b4be29b38fcc663bab4229c1a585 216 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 3.5E-90 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 NPD12_2549 4d59b4be29b38fcc663bab4229c1a585 216 PIRSF PIRSF001461 1 216 7.4E-93 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 NPD12_2549 4d59b4be29b38fcc663bab4229c1a585 216 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 3.7E-82 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 NPD12_320 05cae1ef0d8c22cf5992591876f5bb3d 240 SUPERFAMILY SSF52402 2 214 2.18E-51 T 12-10-2018 NPD12_320 05cae1ef0d8c22cf5992591876f5bb3d 240 Pfam PF01171 PP-loop family 24 200 2.9E-20 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 NPD12_320 05cae1ef0d8c22cf5992591876f5bb3d 240 PIRSF PIRSF004976 1 240 8.8E-65 T 12-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 NPD12_320 05cae1ef0d8c22cf5992591876f5bb3d 240 Gene3D G3DSA:3.40.50.620 1 237 3.0E-53 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2576 b585c3d32001cca4d717d1122026070f 239 Gene3D G3DSA:3.60.140.10 8 239 3.8E-60 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily NPD12_2576 b585c3d32001cca4d717d1122026070f 239 SUPERFAMILY SSF64438 33 237 1.15E-57 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic NPD12_2576 b585c3d32001cca4d717d1122026070f 239 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 39 236 2.7E-53 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase NPD12_2576 b585c3d32001cca4d717d1122026070f 239 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 234 2.8E-55 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase NPD12_1479 e44597cb0866be2028f7333e96dc5110 329 Gene3D G3DSA:3.70.10.10 113 325 2.5E-42 T 12-10-2018 NPD12_1479 e44597cb0866be2028f7333e96dc5110 329 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 216 319 2.3E-15 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 NPD12_1479 e44597cb0866be2028f7333e96dc5110 329 SMART SM00480 10 324 2.6E-8 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 NPD12_1479 e44597cb0866be2028f7333e96dc5110 329 Gene3D G3DSA:3.10.150.10 91 207 2.5E-42 T 12-10-2018 NPD12_1479 e44597cb0866be2028f7333e96dc5110 329 SUPERFAMILY SSF55979 109 206 6.75E-7 T 12-10-2018 NPD12_1479 e44597cb0866be2028f7333e96dc5110 329 SUPERFAMILY SSF55979 217 327 1.23E-19 T 12-10-2018 NPD12_1479 e44597cb0866be2028f7333e96dc5110 329 Pfam PF02767 DNA polymerase III beta subunit, central domain 112 203 1.6E-9 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 NPD12_1302 0442bdeca74852dd08a9c48c86169568 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 250 5.1E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1302 0442bdeca74852dd08a9c48c86169568 268 SUPERFAMILY SSF161098 6 258 4.21E-49 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1302 0442bdeca74852dd08a9c48c86169568 268 Gene3D G3DSA:1.10.3720.10 1 254 3.9E-43 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3294 dcf53613f41fc69474fd715e4296632a 786 Pfam PF02901 Pyruvate formate lyase-like 1 648 3.8E-235 T 12-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 NPD12_3294 dcf53613f41fc69474fd715e4296632a 786 Pfam PF01228 Glycine radical 664 767 4.1E-33 T 12-10-2018 IPR001150 Glycine radical domain GO:0003824 NPD12_3294 dcf53613f41fc69474fd715e4296632a 786 Gene3D G3DSA:3.20.70.40 1 785 1.3E-283 T 12-10-2018 NPD12_3294 dcf53613f41fc69474fd715e4296632a 786 SUPERFAMILY SSF51998 1 784 2.69E-240 T 12-10-2018 NPD12_3124 741fb8f91268d9de59c4b2bfcedf819c 274 SUPERFAMILY SSF49785 13 142 8.25E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_3124 741fb8f91268d9de59c4b2bfcedf819c 274 Gene3D G3DSA:2.60.120.260 13 161 1.2E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_3124 741fb8f91268d9de59c4b2bfcedf819c 274 Pfam PF00754 F5/8 type C domain 24 138 1.4E-8 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 SUPERFAMILY SSF48008 91 226 2.48E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 SUPERFAMILY SSF46785 4 78 9.67E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 Gene3D G3DSA:1.20.120.530 89 227 3.0E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 SMART SM00895 95 219 1.0E-21 T 12-10-2018 IPR011711 GntR, C-terminal NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.2E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 SMART SM00345 15 74 1.8E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 Gene3D G3DSA:1.10.10.10 8 74 1.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2262 8fdcdf74e3d1246ced24d9810b1835ce 229 Pfam PF07729 FCD domain 95 217 5.9E-25 T 12-10-2018 IPR011711 GntR, C-terminal NPD12_422 7fba0427ef0df90f64510aa9ea96383f 163 SUPERFAMILY SSF56176 1 61 4.63E-8 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_422 7fba0427ef0df90f64510aa9ea96383f 163 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 61 3.0E-5 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 NPD12_422 7fba0427ef0df90f64510aa9ea96383f 163 Gene3D G3DSA:3.30.465.10 4 65 3.0E-7 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 NPD12_250 e8a5af088c484c356740129424562b9e 171 SUPERFAMILY SSF102114 27 139 4.84E-12 T 12-10-2018 NPD12_250 e8a5af088c484c356740129424562b9e 171 PIRSF PIRSF000368 1 171 7.6E-54 T 12-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 NPD12_250 e8a5af088c484c356740129424562b9e 171 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 12-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 NPD12_250 e8a5af088c484c356740129424562b9e 171 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 12 157 5.2E-46 T 12-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 NPD12_250 e8a5af088c484c356740129424562b9e 171 Gene3D G3DSA:3.20.20.70 6 169 3.6E-34 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_250 e8a5af088c484c356740129424562b9e 171 Pfam PF04055 Radical SAM superfamily 25 108 4.4E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_250 e8a5af088c484c356740129424562b9e 171 Pfam PF13353 4Fe-4S single cluster domain 17 155 1.1E-39 T 12-10-2018 NPD12_1171 fa21dc4f7fe81ac3902f62db7083e21c 48 SUPERFAMILY SSF159894 6 48 2.88E-15 T 12-10-2018 NPD12_1171 fa21dc4f7fe81ac3902f62db7083e21c 48 Pfam PF04993 TfoX N-terminal domain 13 48 2.9E-8 T 12-10-2018 IPR007076 TfoX, N-terminal NPD12_1171 fa21dc4f7fe81ac3902f62db7083e21c 48 Gene3D G3DSA:3.30.1460.30 3 48 1.9E-8 T 12-10-2018 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 SUPERFAMILY SSF53623 111 295 6.11E-42 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 SUPERFAMILY SSF51984 15 105 1.23E-13 T 12-10-2018 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 15 458 31.338 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 Gene3D G3DSA:3.40.1190.10 107 309 1.8E-56 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 SUPERFAMILY SSF53244 313 458 2.78E-37 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 Pfam PF08245 Mur ligase middle domain 122 294 1.1E-35 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 Gene3D G3DSA:3.40.50.720 12 104 2.3E-16 T 12-10-2018 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 Gene3D G3DSA:3.90.190.20 319 458 6.5E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 NPD12_3689 090fcfc229424e5ab98fb3e5e8699dfc 458 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 16 456 9.7E-111 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 NPD12_2237 0cd52e0fd4c333c5e26575516f0372e5 694 Pfam PF11958 Domain of unknown function (DUF3472) 92 249 2.8E-33 T 12-10-2018 IPR021862 Protein of unknown function DUF3472 NPD12_2237 0cd52e0fd4c333c5e26575516f0372e5 694 SMART SM00495 645 689 4.5E-10 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 NPD12_2237 0cd52e0fd4c333c5e26575516f0372e5 694 SUPERFAMILY SSF51055 643 688 2.35E-11 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 NPD12_2237 0cd52e0fd4c333c5e26575516f0372e5 694 Gene3D G3DSA:2.10.10.20 632 693 2.6E-13 T 12-10-2018 NPD12_2237 0cd52e0fd4c333c5e26575516f0372e5 694 Pfam PF03272 Putative mucin or carbohydrate-binding module 381 492 1.6E-27 T 12-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain NPD12_2237 0cd52e0fd4c333c5e26575516f0372e5 694 Pfam PF03272 Putative mucin or carbohydrate-binding module 518 632 2.1E-30 T 12-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain NPD12_118 3b3d60b8c97b50845feb40cc636975c0 254 Gene3D G3DSA:3.40.50.300 1 254 6.5E-79 T 12-10-2018 NPD12_118 3b3d60b8c97b50845feb40cc636975c0 254 SUPERFAMILY SSF52540 2 252 1.54E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_118 3b3d60b8c97b50845feb40cc636975c0 254 Pfam PF13614 AAA domain 2 179 1.9E-68 T 12-10-2018 IPR025669 AAA domain NPD12_118 3b3d60b8c97b50845feb40cc636975c0 254 PIRSF PIRSF009320 91 254 7.4E-8 T 12-10-2018 NPD12_118 3b3d60b8c97b50845feb40cc636975c0 254 PIRSF PIRSF009320 1 86 2.3E-12 T 12-10-2018 NPD12_2870 4421f5f2ff77b539401fcc83489a2903 200 Gene3D G3DSA:1.10.357.10 5 185 2.3E-36 T 12-10-2018 NPD12_2870 4421f5f2ff77b539401fcc83489a2903 200 SUPERFAMILY SSF46689 7 72 4.77E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2870 4421f5f2ff77b539401fcc83489a2903 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 58 5.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 238 250 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 3 318 1.2E-152 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 SUPERFAMILY SSF51569 2 321 2.05E-144 T 12-10-2018 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 Gene3D G3DSA:3.20.20.70 1 320 2.5E-152 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 293 312 5.3E-60 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 263 278 5.3E-60 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 118 132 5.3E-60 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 186 205 5.3E-60 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 238 254 5.3E-60 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 148 167 5.3E-60 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 SMART SM01004 1 319 4.7E-234 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_1108 07a60fe480c171cea23d21bbb4986e61 324 PIRSF PIRSF001415 1 322 7.4E-151 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 NPD12_3563 205b0f797b2518461ee6ffffe82b7df4 160 Gene3D G3DSA:1.20.1260.10 7 154 3.2E-10 T 12-10-2018 IPR012347 Ferritin-like NPD12_3563 205b0f797b2518461ee6ffffe82b7df4 160 Pfam PF07875 Coat F domain 98 160 6.2E-24 T 12-10-2018 IPR012851 Spore coat protein CotF-like NPD12_3563 205b0f797b2518461ee6ffffe82b7df4 160 SUPERFAMILY SSF47240 10 157 1.44E-27 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_3587 ae0d350a8b0bc4e09219e5dddfb29cf4 532 Gene3D G3DSA:3.30.70.2700 1 78 8.4E-16 T 12-10-2018 NPD12_3587 ae0d350a8b0bc4e09219e5dddfb29cf4 532 Gene3D G3DSA:3.50.50.60 82 304 3.7E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3587 ae0d350a8b0bc4e09219e5dddfb29cf4 532 Gene3D G3DSA:3.50.50.60 464 530 1.7E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3587 ae0d350a8b0bc4e09219e5dddfb29cf4 532 Pfam PF03486 HI0933-like protein 99 262 7.2E-7 T 12-10-2018 NPD12_3587 ae0d350a8b0bc4e09219e5dddfb29cf4 532 SUPERFAMILY SSF51905 95 525 8.07E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3587 ae0d350a8b0bc4e09219e5dddfb29cf4 532 PIRSF PIRSF038984 1 532 5.3E-242 T 12-10-2018 IPR028348 FAD dependent protein NPD12_3054 78c30180d32930b474221515984515ac 469 Pfam PF03237 Terminase-like family 59 224 7.8E-6 T 12-10-2018 IPR004921 Terminase large subunit, T4likevirus-type NPD12_3054 78c30180d32930b474221515984515ac 469 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 319 460 2.4E-34 T 12-10-2018 IPR006517 Archaeophage PsiM2, terminase large subunit NPD12_3054 78c30180d32930b474221515984515ac 469 Pfam PF17289 Terminase RNaseH-like domain 310 454 5.1E-7 T 12-10-2018 IPR035421 Terminase, large subunit gp17-like NPD12_3054 78c30180d32930b474221515984515ac 469 Gene3D G3DSA:3.40.50.300 6 224 1.4E-6 T 12-10-2018 NPD12_2244 28c966668f1250d3b8a0cff910e1642d 220 SUPERFAMILY SSF51182 97 216 1.42E-24 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_2244 28c966668f1250d3b8a0cff910e1642d 220 Pfam PF06249 Ethanolamine utilisation protein EutQ 79 217 1.8E-35 T 12-10-2018 IPR010424 Ethanolamine utilisation EutQ NPD12_2244 28c966668f1250d3b8a0cff910e1642d 220 Gene3D G3DSA:2.60.120.10 83 219 7.5E-50 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1272 abf4cf428c7c5f35b8da209ede101216 73 SMART SM00899 1 73 1.7E-20 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1272 abf4cf428c7c5f35b8da209ede101216 73 Gene3D G3DSA:2.30.30.90 1 73 2.3E-22 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain NPD12_1272 abf4cf428c7c5f35b8da209ede101216 73 SUPERFAMILY SSF50037 5 71 6.41E-18 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal NPD12_1272 abf4cf428c7c5f35b8da209ede101216 73 Pfam PF04023 FeoA domain 1 71 1.2E-15 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 NPD12_1983 122025d474c020238f98a58884973088 334 Gene3D G3DSA:3.30.1330.10 6 152 9.5E-53 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_1983 122025d474c020238f98a58884973088 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 159 310 1.6E-17 T 12-10-2018 IPR010918 PurM-like, C-terminal domain NPD12_1983 122025d474c020238f98a58884973088 334 SUPERFAMILY SSF55326 6 152 3.66E-33 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_1983 122025d474c020238f98a58884973088 334 PIRSF PIRSF005644 1 334 7.9E-120 T 12-10-2018 IPR011854 Carbamoyl dehydratase HypE NPD12_1983 122025d474c020238f98a58884973088 334 Gene3D G3DSA:3.90.650.10 153 334 2.2E-46 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_1983 122025d474c020238f98a58884973088 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 149 2.1E-15 T 12-10-2018 IPR016188 PurM-like, N-terminal domain NPD12_1983 122025d474c020238f98a58884973088 334 SUPERFAMILY SSF56042 156 329 6.28E-36 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily NPD12_1983 122025d474c020238f98a58884973088 334 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 5 334 4.6E-131 T 12-10-2018 IPR011854 Carbamoyl dehydratase HypE NPD12_1387 60d1ad13993bbbe4cdb17498ecc2e0c1 313 Gene3D G3DSA:3.30.420.40 2 104 1.9E-26 T 12-10-2018 NPD12_1387 60d1ad13993bbbe4cdb17498ecc2e0c1 313 Gene3D G3DSA:3.30.420.40 105 300 1.2E-36 T 12-10-2018 NPD12_1387 60d1ad13993bbbe4cdb17498ecc2e0c1 313 Pfam PF00480 ROK family 6 293 1.8E-39 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 NPD12_1387 60d1ad13993bbbe4cdb17498ecc2e0c1 313 SUPERFAMILY SSF53067 5 295 3.01E-46 T 12-10-2018 NPD12_1480 b4a10c2719a6a08570ddedbcb1cb84aa 621 Gene3D G3DSA:3.40.50.300 353 529 8.9E-14 T 12-10-2018 NPD12_1480 b4a10c2719a6a08570ddedbcb1cb84aa 621 SMART SM00885 227 345 1.9E-6 T 12-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal NPD12_1480 b4a10c2719a6a08570ddedbcb1cb84aa 621 SUPERFAMILY SSF52540 351 519 5.41E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1480 b4a10c2719a6a08570ddedbcb1cb84aa 621 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 295 590 3.7E-67 T 12-10-2018 IPR006500 DNA primase, phage/plasmid NPD12_1480 b4a10c2719a6a08570ddedbcb1cb84aa 621 Pfam PF08706 D5 N terminal like 233 345 9.9E-6 T 12-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal NPD12_2015 4ff7964ef2fd11702452545d17669bec 82 SUPERFAMILY SSF55021 3 80 3.84E-15 T 12-10-2018 NPD12_2015 4ff7964ef2fd11702452545d17669bec 82 Gene3D G3DSA:3.30.70.1150 1 82 4.4E-8 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal NPD12_749 6e587d732335470f3a04b91cc418612f 282 Pfam PF00805 Pentapeptide repeats (8 copies) 212 250 1.5E-10 T 12-10-2018 IPR001646 Pentapeptide repeat NPD12_749 6e587d732335470f3a04b91cc418612f 282 SUPERFAMILY SSF141571 59 277 9.94E-20 T 12-10-2018 NPD12_749 6e587d732335470f3a04b91cc418612f 282 Gene3D G3DSA:2.160.20.80 146 270 4.1E-14 T 12-10-2018 NPD12_600 fb39461093c613c71d9a5436998da8cf 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 1.3E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_600 fb39461093c613c71d9a5436998da8cf 202 Gene3D G3DSA:1.10.357.10 6 192 3.8E-37 T 12-10-2018 NPD12_600 fb39461093c613c71d9a5436998da8cf 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 8.0E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_600 fb39461093c613c71d9a5436998da8cf 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 8.0E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_600 fb39461093c613c71d9a5436998da8cf 202 SUPERFAMILY SSF46689 7 65 5.99E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_600 fb39461093c613c71d9a5436998da8cf 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site NPD12_487 7a41c269051be2d956d2a53ede2fa0fb 135 SUPERFAMILY SSF81301 8 106 5.79E-16 T 12-10-2018 NPD12_487 7a41c269051be2d956d2a53ede2fa0fb 135 Gene3D G3DSA:3.30.460.10 1 107 1.1E-20 T 12-10-2018 NPD12_487 7a41c269051be2d956d2a53ede2fa0fb 135 Pfam PF01909 Nucleotidyltransferase domain 9 74 5.6E-12 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 NPD12_1933 46f54f60fa829ab289957f1546396fe5 1482 SUPERFAMILY SSF63825 346 533 1.44E-7 T 12-10-2018 NPD12_1933 46f54f60fa829ab289957f1546396fe5 1482 Pfam PF07532 Bacterial Ig-like domain (group 4) 669 723 1.8E-12 T 12-10-2018 IPR011081 Bacterial Ig-related NPD12_1933 46f54f60fa829ab289957f1546396fe5 1482 Pfam PF16472 Domain of unknown function (DUF5050) 488 629 1.6E-24 T 12-10-2018 IPR032485 Domain of unknown function DUF5050 NPD12_1933 46f54f60fa829ab289957f1546396fe5 1482 Pfam PF16472 Domain of unknown function (DUF5050) 341 458 1.5E-26 T 12-10-2018 IPR032485 Domain of unknown function DUF5050 NPD12_1933 46f54f60fa829ab289957f1546396fe5 1482 SUPERFAMILY SSF63825 495 629 3.14E-5 T 12-10-2018 NPD12_3149 dc67b917fd6f14192f0abfa9df804fa8 301 Pfam PF09681 N-terminal phage replisome organiser (Phage_rep_org_N) 15 134 1.2E-54 T 12-10-2018 IPR010056 Phage replisome organiser, N-terminal domain NPD12_3149 dc67b917fd6f14192f0abfa9df804fa8 301 SUPERFAMILY SSF158499 198 264 4.97E-5 T 12-10-2018 IPR034829 DnaD-like domain superfamily NPD12_3149 dc67b917fd6f14192f0abfa9df804fa8 301 TIGRFAM TIGR01714 phage_rep_org_N: phage replisome organizer, putative, N-terminal region 15 134 1.9E-42 T 12-10-2018 IPR010056 Phage replisome organiser, N-terminal domain NPD12_56 6f50bb2ed6e808f7db953a28624a2d79 225 SMART SM00481 3 70 2.7E-8 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal NPD12_56 6f50bb2ed6e808f7db953a28624a2d79 225 Pfam PF13263 PHP-associated 139 193 1.8E-17 T 12-10-2018 NPD12_56 6f50bb2ed6e808f7db953a28624a2d79 225 SUPERFAMILY SSF89550 1 196 5.89E-40 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_56 6f50bb2ed6e808f7db953a28624a2d79 225 Gene3D G3DSA:3.20.20.140 1 207 9.3E-38 T 12-10-2018 NPD12_56 6f50bb2ed6e808f7db953a28624a2d79 225 Pfam PF02811 PHP domain 4 95 2.8E-9 T 12-10-2018 IPR004013 PHP domain GO:0003824 NPD12_1357 7b97211b4861d390962f7ab681760ad8 303 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 179 298 1.3E-37 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain NPD12_1357 7b97211b4861d390962f7ab681760ad8 303 Gene3D G3DSA:3.40.50.720 1 176 9.9E-53 T 12-10-2018 NPD12_1357 7b97211b4861d390962f7ab681760ad8 303 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 151 1.2E-39 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain NPD12_1357 7b97211b4861d390962f7ab681760ad8 303 SUPERFAMILY SSF48179 180 301 3.37E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 NPD12_1357 7b97211b4861d390962f7ab681760ad8 303 Gene3D G3DSA:1.10.1040.10 178 303 1.6E-39 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 NPD12_1357 7b97211b4861d390962f7ab681760ad8 303 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 302 1.2E-85 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 NPD12_1357 7b97211b4861d390962f7ab681760ad8 303 SUPERFAMILY SSF51735 1 160 1.02E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1244 8f64141fa23c5a4ab8aabe3f0b94ad21 457 Gene3D G3DSA:3.30.565.10 307 456 5.5E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1244 8f64141fa23c5a4ab8aabe3f0b94ad21 457 SUPERFAMILY SSF55874 318 446 5.74E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_1244 8f64141fa23c5a4ab8aabe3f0b94ad21 457 Pfam PF14501 GHKL domain 350 454 5.7E-25 T 12-10-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain NPD12_1741 3406d45e0b0637cb9b679c806b2e971e 309 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 4 177 2.5E-43 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain NPD12_1741 3406d45e0b0637cb9b679c806b2e971e 309 SUPERFAMILY SSF52540 3 193 7.32E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1741 3406d45e0b0637cb9b679c806b2e971e 309 Gene3D G3DSA:3.40.50.300 1 194 1.4E-51 T 12-10-2018 NPD12_1741 3406d45e0b0637cb9b679c806b2e971e 309 SUPERFAMILY SSF90002 217 301 7.98E-6 T 12-10-2018 NPD12_1741 3406d45e0b0637cb9b679c806b2e971e 309 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 218 301 4.7E-5 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal NPD12_2193 e1211136eac86d2be38810007552c6a9 825 SUPERFAMILY SSF103647 484 565 9.68E-6 T 12-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 NPD12_2193 e1211136eac86d2be38810007552c6a9 825 SUPERFAMILY SSF53474 573 775 9.47E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2193 e1211136eac86d2be38810007552c6a9 825 Gene3D G3DSA:3.40.50.1820 594 819 5.6E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2193 e1211136eac86d2be38810007552c6a9 825 Pfam PF11187 Protein of unknown function (DUF2974) 633 769 6.8E-8 T 12-10-2018 IPR024499 Protein of unknown function DUF2974 NPD12_2193 e1211136eac86d2be38810007552c6a9 825 Gene3D G3DSA:2.60.40.10 49 132 1.3E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_1689 82b24194861d6d7ca516ccf5482b568d 399 SUPERFAMILY SSF56796 15 397 6.02E-99 T 12-10-2018 NPD12_1689 82b24194861d6d7ca516ccf5482b568d 399 Pfam PF00465 Iron-containing alcohol dehydrogenase 18 375 2.5E-91 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 NPD12_1689 82b24194861d6d7ca516ccf5482b568d 399 Gene3D G3DSA:1.20.1090.10 198 398 2.7E-40 T 12-10-2018 NPD12_1689 82b24194861d6d7ca516ccf5482b568d 399 Gene3D G3DSA:3.40.50.1970 11 197 1.2E-49 T 12-10-2018 NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 SUPERFAMILY SSF55031 161 283 6.73E-15 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 SUPERFAMILY SSF53187 7 397 6.79E-59 T 12-10-2018 NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 Pfam PF01546 Peptidase family M20/M25/M40 77 393 1.8E-27 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 Gene3D G3DSA:3.40.630.10 24 387 1.5E-71 T 12-10-2018 NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 TIGRFAM TIGR03526 selenium_YgeY: putative selenium metabolism hydrolase 7 400 5.1E-228 T 12-10-2018 IPR017706 Peptidase M20/DapE, YgeY NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 Gene3D G3DSA:3.30.70.360 185 299 1.5E-71 T 12-10-2018 NPD12_2934 9c99e1a165c2aa901fdfa5683a26edfe 405 Pfam PF07687 Peptidase dimerisation domain 182 286 6.0E-19 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_1653 f943ac1ea2134103a6d9bd42249e1cfe 278 Gene3D G3DSA:3.40.1190.20 2 278 3.2E-69 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1653 f943ac1ea2134103a6d9bd42249e1cfe 278 Pfam PF08543 Phosphomethylpyrimidine kinase 74 260 5.6E-24 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 NPD12_1653 f943ac1ea2134103a6d9bd42249e1cfe 278 SUPERFAMILY SSF53613 5 276 7.79E-58 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1383 4d9aab2aa7e3f48505e9f64f42dbbb74 575 SUPERFAMILY SSF51905 56 571 1.39E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1383 4d9aab2aa7e3f48505e9f64f42dbbb74 575 Gene3D G3DSA:3.50.50.60 60 565 1.5E-76 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1383 4d9aab2aa7e3f48505e9f64f42dbbb74 575 Gene3D G3DSA:1.20.1440.240 165 269 1.5E-76 T 12-10-2018 NPD12_1383 4d9aab2aa7e3f48505e9f64f42dbbb74 575 Pfam PF01593 Flavin containing amine oxidoreductase 68 567 1.6E-42 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 NPD12_1383 4d9aab2aa7e3f48505e9f64f42dbbb74 575 SUPERFAMILY SSF54373 380 516 5.73E-17 T 12-10-2018 NPD12_1383 4d9aab2aa7e3f48505e9f64f42dbbb74 575 Gene3D G3DSA:3.90.660.10 99 511 1.5E-76 T 12-10-2018 NPD12_1750 73279ba72354f195b5b7da5910289251 339 SUPERFAMILY SSF51395 1 338 9.77E-83 T 12-10-2018 NPD12_1750 73279ba72354f195b5b7da5910289251 339 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 317 2.9E-56 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 NPD12_1750 73279ba72354f195b5b7da5910289251 339 Gene3D G3DSA:3.20.20.70 1 339 3.3E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_525 4ec692e05b0d711fa247ae9c1371104e 422 Gene3D G3DSA:1.20.1530.20 9 405 2.8E-35 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_525 4ec692e05b0d711fa247ae9c1371104e 422 Pfam PF00999 Sodium/hydrogen exchanger family 18 398 9.3E-54 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 NPD12_1979 515fc3fd27a87de9446c4baf6925c755 80 SUPERFAMILY SSF52833 3 78 3.13E-11 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_1979 515fc3fd27a87de9446c4baf6925c755 80 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 3 71 4.8E-7 T 12-10-2018 NPD12_1979 515fc3fd27a87de9446c4baf6925c755 80 Gene3D G3DSA:3.40.30.10 2 78 2.7E-14 T 12-10-2018 NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 SMART SM00387 220 332 1.6E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 SUPERFAMILY SSF47384 112 174 1.02E-5 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 Gene3D G3DSA:3.30.565.10 174 329 3.7E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 SUPERFAMILY SSF55874 166 330 7.33E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 223 331 3.0E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 Gene3D G3DSA:1.10.287.130 128 173 3.7E-30 T 12-10-2018 NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 310 1.7E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 329 1.7E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_2271 63fe2f35a2adf6bef96c6a7747d00f8c 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 258 272 1.7E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_1698 932b05dcf363b225106e1fe657410c6f 433 SUPERFAMILY SSF56425 219 329 2.09E-33 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 NPD12_1698 932b05dcf363b225106e1fe657410c6f 433 SUPERFAMILY SSF51905 5 388 1.65E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1698 932b05dcf363b225106e1fe657410c6f 433 Gene3D G3DSA:3.50.50.60 6 380 4.8E-127 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1698 932b05dcf363b225106e1fe657410c6f 433 Pfam PF00890 FAD binding domain 6 369 2.4E-75 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 NPD12_1698 932b05dcf363b225106e1fe657410c6f 433 Gene3D G3DSA:3.90.700.10 227 324 4.8E-127 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 SMART SM00387 350 462 1.1E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 Gene3D G3DSA:1.20.1480.50 158 248 1.2E-8 T 12-10-2018 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 SUPERFAMILY SSF55874 297 460 2.49E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 SMART SM00304 188 241 0.0054 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 SUPERFAMILY SSF158472 189 237 5.49E-6 T 12-10-2018 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 Gene3D G3DSA:3.30.565.10 310 462 1.7E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 7.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 7.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 7.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 7.7E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 459 5.2E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 SUPERFAMILY SSF47384 225 307 6.47E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 304 4.7E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 Gene3D G3DSA:1.10.287.130 249 307 8.5E-11 T 12-10-2018 NPD12_433 82dbb8d12665388623cb01b46b60b69f 465 SMART SM00388 242 306 4.8E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 NPD12_1683 d852fcb39e5d31c2d0ec6a574d932280 283 SUPERFAMILY SSF53187 79 282 3.77E-37 T 12-10-2018 NPD12_1683 d852fcb39e5d31c2d0ec6a574d932280 283 SMART SM00646 161 279 8.6E-22 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_1683 d852fcb39e5d31c2d0ec6a574d932280 283 Gene3D G3DSA:3.40.630.40 77 283 1.5E-47 T 12-10-2018 NPD12_1683 d852fcb39e5d31c2d0ec6a574d932280 283 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 81 279 1.0E-41 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3262 b291a4a96dbb880bd8ff338bdc57445a 309 SUPERFAMILY SSF161098 91 292 8.94E-18 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3262 b291a4a96dbb880bd8ff338bdc57445a 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 2.0E-42 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_3262 b291a4a96dbb880bd8ff338bdc57445a 309 Gene3D G3DSA:1.10.3720.10 85 299 7.6E-19 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_955 8d9b35b9a4549d3a2518e3cd7ffc349e 404 Gene3D G3DSA:3.40.190.10 147 395 1.0E-161 T 12-10-2018 NPD12_955 8d9b35b9a4549d3a2518e3cd7ffc349e 404 Gene3D G3DSA:3.40.190.10 40 363 1.0E-161 T 12-10-2018 NPD12_955 8d9b35b9a4549d3a2518e3cd7ffc349e 404 Pfam PF01547 Bacterial extracellular solute-binding protein 55 321 6.1E-5 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein NPD12_955 8d9b35b9a4549d3a2518e3cd7ffc349e 404 TIGRFAM TIGR04541 thiaminase_BcmE: thiamine pyridinylase 11 392 4.4E-213 T 12-10-2018 IPR030901 Thiaminase-1 KEGG: 00730+2.5.1.2 NPD12_955 8d9b35b9a4549d3a2518e3cd7ffc349e 404 SUPERFAMILY SSF53850 39 401 4.55E-47 T 12-10-2018 NPD12_891 bb3f6599cadac2316d69d2fc976747ad 69 Pfam PF01381 Helix-turn-helix 7 61 7.1E-18 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_891 bb3f6599cadac2316d69d2fc976747ad 69 SUPERFAMILY SSF47413 5 65 1.1E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_891 bb3f6599cadac2316d69d2fc976747ad 69 SMART SM00530 6 61 9.2E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_891 bb3f6599cadac2316d69d2fc976747ad 69 Gene3D G3DSA:1.10.260.40 2 67 1.1E-27 T 12-10-2018 NPD12_1274 0c518df3a2c7840207a88921f6aab966 241 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 4 205 4.1E-61 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like NPD12_1274 0c518df3a2c7840207a88921f6aab966 241 Gene3D G3DSA:3.40.50.1000 1 223 1.0E-33 T 12-10-2018 IPR023214 HAD superfamily NPD12_1274 0c518df3a2c7840207a88921f6aab966 241 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 194 6.2E-38 T 12-10-2018 NPD12_1274 0c518df3a2c7840207a88921f6aab966 241 SUPERFAMILY SSF56784 3 225 1.9E-28 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_1274 0c518df3a2c7840207a88921f6aab966 241 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 192 1.5E-19 T 12-10-2018 NPD12_513 c2c9284e2b1f3da136ee7d430c52af0a 336 Gene3D G3DSA:2.120.10.70 86 325 8.9E-10 T 12-10-2018 NPD12_513 c2c9284e2b1f3da136ee7d430c52af0a 336 SUPERFAMILY SSF89372 69 300 1.31E-56 T 12-10-2018 NPD12_513 c2c9284e2b1f3da136ee7d430c52af0a 336 Pfam PF03984 Repeat of unknown function (DUF346) 142 175 1.9E-9 T 12-10-2018 IPR007132 Protein of unknown function DUF346 NPD12_513 c2c9284e2b1f3da136ee7d430c52af0a 336 Pfam PF03984 Repeat of unknown function (DUF346) 187 220 2.3E-8 T 12-10-2018 IPR007132 Protein of unknown function DUF346 NPD12_513 c2c9284e2b1f3da136ee7d430c52af0a 336 Pfam PF03984 Repeat of unknown function (DUF346) 231 266 4.5E-9 T 12-10-2018 IPR007132 Protein of unknown function DUF346 NPD12_379 63cc4ea9bbf0c924a4daa45992e5df5a 367 Pfam PF02653 Branched-chain amino acid transport system / permease component 74 346 2.7E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 NPD12_304 44b4f758e12d432226cde8ea421140b5 122 Pfam PF03899 ATP synthase I chain 11 104 2.6E-11 T 12-10-2018 IPR005598 ATP synthase protein I NPD12_1492 3934789e50201542a896f1407e122637 114 Pfam PF05135 Phage gp6-like head-tail connector protein 1 109 8.6E-10 T 12-10-2018 IPR021146 Phage gp6-like head-tail connector protein NPD12_3075 7eda854ee41f0ffe2a200415cc5e6dd3 64 Gene3D G3DSA:1.10.260.40 2 64 7.2E-16 T 12-10-2018 NPD12_3075 7eda854ee41f0ffe2a200415cc5e6dd3 64 SMART SM00530 6 62 4.2E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3075 7eda854ee41f0ffe2a200415cc5e6dd3 64 SUPERFAMILY SSF47413 1 63 1.13E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3075 7eda854ee41f0ffe2a200415cc5e6dd3 64 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 63 1.9E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 SUPERFAMILY SSF51971 1 357 2.3E-47 T 12-10-2018 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 Gene3D G3DSA:3.40.50.720 1 128 6.4E-33 T 12-10-2018 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 Gene3D G3DSA:3.40.50.720 254 365 1.2E-20 T 12-10-2018 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 Gene3D G3DSA:3.40.50.720 131 253 3.6E-23 T 12-10-2018 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 Pfam PF03275 UDP-galactopyranose mutase 146 346 2.1E-84 T 12-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 1 362 6.1E-131 T 12-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 71 2.3E-18 T 12-10-2018 NPD12_2733 6c38882604ff5d4b78f142556c40e041 366 SUPERFAMILY SSF54373 245 313 3.53E-26 T 12-10-2018 NPD12_365 0bc3cf65232442a110799f1794de4477 321 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 176 187 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_365 0bc3cf65232442a110799f1794de4477 321 Pfam PF13484 4Fe-4S double cluster binding domain 175 234 1.3E-10 T 12-10-2018 NPD12_365 0bc3cf65232442a110799f1794de4477 321 SUPERFAMILY SSF46548 122 236 9.94E-12 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 NPD12_365 0bc3cf65232442a110799f1794de4477 321 Pfam PF08331 Domain of unknown function (DUF1730) 54 123 9.1E-14 T 12-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 NPD12_365 0bc3cf65232442a110799f1794de4477 321 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 301 1.7E-76 T 12-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 SMART SM00533 9 311 2.1E-9 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 SUPERFAMILY SSF48334 21 284 2.09E-21 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 SMART SM00534 322 507 3.8E-59 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 Gene3D G3DSA:1.10.1420.10 21 277 1.1E-7 T 12-10-2018 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 Gene3D G3DSA:3.40.50.300 288 582 1.3E-68 T 12-10-2018 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 Pfam PF00488 MutS domain V 325 506 4.8E-34 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 404 420 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 Gene3D G3DSA:1.10.1420.10 113 223 1.1E-7 T 12-10-2018 NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 SUPERFAMILY SSF52540 289 508 2.8E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_808 f328d1913c68cf04bc39510cd26b1a21 631 PIRSF PIRSF005814 1 631 7.1E-192 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 NPD12_1498 63aa07878a611eea6fb4e8535eee988d 154 SUPERFAMILY SSF69279 7 148 2.21E-47 T 12-10-2018 NPD12_1498 63aa07878a611eea6fb4e8535eee988d 154 Pfam PF09393 Phage tail tube protein 4 146 5.0E-52 T 12-10-2018 IPR018989 Phage tail tube protein NPD12_1498 63aa07878a611eea6fb4e8535eee988d 154 Gene3D G3DSA:2.30.110.40 3 147 3.7E-52 T 12-10-2018 IPR038628 XkdM-like superfamily NPD12_703 1aa6efd7f928e98359fa238ccd99da88 457 Gene3D G3DSA:1.20.1740.10 6 455 7.3E-94 T 12-10-2018 NPD12_703 1aa6efd7f928e98359fa238ccd99da88 457 Pfam PF13520 Amino acid permease 11 411 3.9E-57 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_703 1aa6efd7f928e98359fa238ccd99da88 457 PIRSF PIRSF006060 1 453 2.6E-72 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_1432 12e4adb28e55654fc1aa7655b79f81f8 243 Pfam PF00005 ABC transporter 22 163 1.2E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1432 12e4adb28e55654fc1aa7655b79f81f8 243 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1432 12e4adb28e55654fc1aa7655b79f81f8 243 SMART SM00382 31 228 2.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1432 12e4adb28e55654fc1aa7655b79f81f8 243 Gene3D G3DSA:3.40.50.300 1 235 8.2E-59 T 12-10-2018 NPD12_1432 12e4adb28e55654fc1aa7655b79f81f8 243 SUPERFAMILY SSF52540 4 225 5.33E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_349 22212793b3f8c8464c2569803bcd9aeb 179 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 23 140 7.0E-40 T 12-10-2018 NPD12_349 22212793b3f8c8464c2569803bcd9aeb 179 Pfam PF01928 CYTH domain 2 167 3.1E-22 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 NPD12_349 22212793b3f8c8464c2569803bcd9aeb 179 Gene3D G3DSA:2.40.320.10 3 174 1.2E-24 T 12-10-2018 NPD12_349 22212793b3f8c8464c2569803bcd9aeb 179 SUPERFAMILY SSF55154 3 173 6.54E-30 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 NPD12_349 22212793b3f8c8464c2569803bcd9aeb 179 SMART SM01118 1 175 2.8E-7 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 Pfam PF00813 FliP family 61 253 2.6E-83 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 234 246 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 179 191 9.7E-24 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 129 143 9.7E-24 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 117 129 9.7E-24 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 57 66 9.7E-24 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 157 169 9.7E-24 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 247 257 9.7E-24 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 186 201 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 61 257 4.2E-88 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 207 228 1.3E-68 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 59 78 1.3E-68 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 231 256 1.3E-68 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 78 98 1.3E-68 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 186 206 1.3E-68 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_2698 83b54fe51e872fc1063973afb6575992 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 98 117 1.3E-68 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 NPD12_1760 5eeb05b21cc8f560947e703844f180d3 274 SUPERFAMILY SSF161098 3 274 4.02E-71 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1760 5eeb05b21cc8f560947e703844f180d3 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 268 2.1E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1760 5eeb05b21cc8f560947e703844f180d3 274 Gene3D G3DSA:1.10.3720.10 1 265 2.3E-65 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1652 b67ccdc0d1e85a532c2577361bd2bf1c 297 Gene3D G3DSA:1.25.40.10 27 275 4.1E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1652 b67ccdc0d1e85a532c2577361bd2bf1c 297 SMART SM00028 34 67 0.0017 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1652 b67ccdc0d1e85a532c2577361bd2bf1c 297 SMART SM00028 82 115 27.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1652 b67ccdc0d1e85a532c2577361bd2bf1c 297 SMART SM00028 131 164 6.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_1652 b67ccdc0d1e85a532c2577361bd2bf1c 297 SUPERFAMILY SSF48452 30 176 8.67E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1091 fe3a28128c608648db1f440b991d8c83 215 Gene3D G3DSA:3.50.30.50 1 212 5.1E-61 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_1091 fe3a28128c608648db1f440b991d8c83 215 SUPERFAMILY SSF102198 1 213 5.36E-59 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_1091 fe3a28128c608648db1f440b991d8c83 215 Pfam PF04199 Putative cyclase 4 155 1.7E-28 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 NPD12_506 e4cfed55bed6414879480fa3dac5003c 181 SUPERFAMILY SSF47413 3 67 1.13E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_506 e4cfed55bed6414879480fa3dac5003c 181 Pfam PF01381 Helix-turn-helix 9 63 8.4E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_506 e4cfed55bed6414879480fa3dac5003c 181 SUPERFAMILY SSF51182 56 181 4.86E-30 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_506 e4cfed55bed6414879480fa3dac5003c 181 Pfam PF07883 Cupin domain 108 175 8.8E-16 T 12-10-2018 IPR013096 Cupin 2, conserved barrel NPD12_506 e4cfed55bed6414879480fa3dac5003c 181 SMART SM00530 8 63 1.9E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_506 e4cfed55bed6414879480fa3dac5003c 181 Gene3D G3DSA:1.10.260.40 1 71 1.7E-19 T 12-10-2018 NPD12_506 e4cfed55bed6414879480fa3dac5003c 181 Gene3D G3DSA:2.60.120.10 72 176 3.9E-22 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_2245 a4d5e5d32bf5d1d2701a446417015480 87 SUPERFAMILY SSF159133 1 82 4.19E-25 T 12-10-2018 IPR036677 EutN/Ccml superfamily NPD12_2245 a4d5e5d32bf5d1d2701a446417015480 87 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 12 81 1.0E-21 T 12-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml NPD12_2245 a4d5e5d32bf5d1d2701a446417015480 87 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 81 3.6E-26 T 12-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml NPD12_2245 a4d5e5d32bf5d1d2701a446417015480 87 Gene3D G3DSA:2.40.50.220 1 86 1.9E-28 T 12-10-2018 IPR036677 EutN/Ccml superfamily NPD12_3637 55a25d8909c1ccc44967dcc2754d2b83 97 Gene3D G3DSA:3.30.70.330 3 97 1.9E-32 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily NPD12_3637 55a25d8909c1ccc44967dcc2754d2b83 97 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 6 96 21.941 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 NPD12_3637 55a25d8909c1ccc44967dcc2754d2b83 97 SUPERFAMILY SSF54189 6 96 4.68E-32 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3637 55a25d8909c1ccc44967dcc2754d2b83 97 Pfam PF00276 Ribosomal protein L23 7 90 8.7E-31 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 NPD12_3637 55a25d8909c1ccc44967dcc2754d2b83 97 ProSitePatterns PS00050 Ribosomal protein L23 signature. 78 93 - T 12-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 NPD12_2823 c8596d81d9287c5ac628f01ba3e99373 126 SUPERFAMILY SSF46785 5 79 2.73E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2823 c8596d81d9287c5ac628f01ba3e99373 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 1.5E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_2823 c8596d81d9287c5ac628f01ba3e99373 126 Gene3D G3DSA:1.10.10.10 8 125 1.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2823 c8596d81d9287c5ac628f01ba3e99373 126 SMART SM00345 16 75 2.1E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_3291 cb204d868bcdb24e79c018ef53de3cc5 291 Pfam PF01925 Sulfite exporter TauE/SafE 169 283 3.1E-8 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_3291 cb204d868bcdb24e79c018ef53de3cc5 291 Pfam PF01925 Sulfite exporter TauE/SafE 7 146 1.7E-8 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_2343 3cf88b3e868ed73202b5e35851c79597 212 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 2 210 1.2E-73 T 12-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 NPD12_2343 3cf88b3e868ed73202b5e35851c79597 212 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 32 193 2.3E-28 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain NPD12_2343 3cf88b3e868ed73202b5e35851c79597 212 SMART SM00382 29 184 0.0012 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2343 3cf88b3e868ed73202b5e35851c79597 212 Gene3D G3DSA:3.40.50.300 12 212 2.6E-58 T 12-10-2018 NPD12_2343 3cf88b3e868ed73202b5e35851c79597 212 PIRSF PIRSF005624 1 211 2.5E-77 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 NPD12_2343 3cf88b3e868ed73202b5e35851c79597 212 SUPERFAMILY SSF52540 2 210 9.7E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1054 5758dd12634d750b2500437b44b55449 478 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 6.3E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1054 5758dd12634d750b2500437b44b55449 478 Gene3D G3DSA:3.40.640.10 103 471 3.5E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1054 5758dd12634d750b2500437b44b55449 478 Gene3D G3DSA:1.10.10.10 1 88 5.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1054 5758dd12634d750b2500437b44b55449 478 SUPERFAMILY SSF46785 8 82 1.34E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1054 5758dd12634d750b2500437b44b55449 478 Pfam PF00155 Aminotransferase class I and II 126 443 2.5E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1054 5758dd12634d750b2500437b44b55449 478 SUPERFAMILY SSF53383 105 477 1.23E-71 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1054 5758dd12634d750b2500437b44b55449 478 SMART SM00345 19 78 3.9E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_164 646ad74befdf1245efb6f6069aa2179a 400 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 NPD12_164 646ad74befdf1245efb6f6069aa2179a 400 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 395 1.0E-154 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 NPD12_164 646ad74befdf1245efb6f6069aa2179a 400 Gene3D G3DSA:3.90.1150.10 264 396 3.1E-59 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_164 646ad74befdf1245efb6f6069aa2179a 400 SUPERFAMILY SSF53383 29 396 2.89E-126 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_164 646ad74befdf1245efb6f6069aa2179a 400 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 7 396 1.3E-184 T 12-10-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 NPD12_164 646ad74befdf1245efb6f6069aa2179a 400 Gene3D G3DSA:3.40.640.10 7 263 2.8E-98 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_164 646ad74befdf1245efb6f6069aa2179a 400 PIRSF PIRSF001434 1 399 9.8E-154 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 Gene3D G3DSA:1.20.58.220 447 538 1.6E-17 T 12-10-2018 IPR038078 PhoU-like domain superfamily NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 Gene3D G3DSA:1.20.58.220 340 439 7.9E-20 T 12-10-2018 IPR038078 PhoU-like domain superfamily NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 SUPERFAMILY SSF109755 332 537 2.41E-53 T 12-10-2018 NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 Pfam PF01895 PhoU domain 450 534 3.7E-15 T 12-10-2018 IPR026022 PhoU domain NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 Pfam PF01895 PhoU domain 346 430 3.3E-17 T 12-10-2018 IPR026022 PhoU domain NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 Pfam PF02690 Na+/Pi-cotransporter 16 151 8.5E-54 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 Pfam PF02690 Na+/Pi-cotransporter 146 258 5.5E-19 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 NPD12_3602 9f106aa199f55ec947b3ed0c05b27cc9 538 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 6 313 7.3E-76 T 12-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 NPD12_2858 dadccf05616efcd291ab54ea78adad6d 155 SUPERFAMILY SSF46785 10 147 5.14E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2858 dadccf05616efcd291ab54ea78adad6d 155 Gene3D G3DSA:3.30.1490.190 98 155 5.9E-14 T 12-10-2018 NPD12_2858 dadccf05616efcd291ab54ea78adad6d 155 Gene3D G3DSA:1.10.10.10 4 87 7.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2858 dadccf05616efcd291ab54ea78adad6d 155 Pfam PF01475 Ferric uptake regulator family 15 143 3.5E-24 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 NPD12_1181 7c712e87491c1cbc50fdb6852ccfd797 722 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 499 702 2.7E-43 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal NPD12_1181 7c712e87491c1cbc50fdb6852ccfd797 722 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 14 176 5.6E-47 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal NPD12_283 8bed0b32639da89663d9b88a08349859 326 Pfam PF05670 Domain of unknown function (DUF814) 226 305 2.1E-6 T 12-10-2018 IPR008532 Domain of unknown function DUF814 NPD12_283 8bed0b32639da89663d9b88a08349859 326 Gene3D G3DSA:3.40.50.620 2 212 1.2E-42 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_283 8bed0b32639da89663d9b88a08349859 326 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 3 140 3.3E-11 T 12-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 NPD12_283 8bed0b32639da89663d9b88a08349859 326 SUPERFAMILY SSF52402 2 226 1.17E-32 T 12-10-2018 NPD12_2368 32e030c9fb4504e99fb3984a1c845ec0 482 Gene3D G3DSA:3.50.50.60 3 347 2.3E-120 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2368 32e030c9fb4504e99fb3984a1c845ec0 482 Gene3D G3DSA:3.30.9.10 86 314 2.3E-120 T 12-10-2018 NPD12_2368 32e030c9fb4504e99fb3984a1c845ec0 482 Gene3D G3DSA:1.10.10.1100 383 457 4.3E-24 T 12-10-2018 NPD12_2368 32e030c9fb4504e99fb3984a1c845ec0 482 Pfam PF01266 FAD dependent oxidoreductase 3 349 2.3E-67 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 NPD12_2368 32e030c9fb4504e99fb3984a1c845ec0 482 SUPERFAMILY SSF51905 1 371 2.89E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2368 32e030c9fb4504e99fb3984a1c845ec0 482 SUPERFAMILY SSF54373 218 311 2.75E-5 T 12-10-2018 NPD12_2368 32e030c9fb4504e99fb3984a1c845ec0 482 Pfam PF04324 BFD-like [2Fe-2S] binding domain 394 448 1.4E-16 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain NPD12_1240 0ea6a1421fe615d24469314f8a0113e6 314 Gene3D G3DSA:3.40.50.12260 184 289 4.5E-93 T 12-10-2018 NPD12_1240 0ea6a1421fe615d24469314f8a0113e6 314 Gene3D G3DSA:3.40.50.1980 48 306 4.5E-93 T 12-10-2018 NPD12_1240 0ea6a1421fe615d24469314f8a0113e6 314 SUPERFAMILY SSF53807 39 306 2.98E-65 T 12-10-2018 NPD12_1240 0ea6a1421fe615d24469314f8a0113e6 314 Pfam PF01497 Periplasmic binding protein 56 290 8.4E-35 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_408 e91f36b7591ed619e0f2b1f52412f787 251 Pfam PF12730 ABC-2 family transporter protein 4 178 1.6E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_1195 2199614ee05b83abc26110b4a412e147 507 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 4 502 9.6E-138 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 NPD12_1195 2199614ee05b83abc26110b4a412e147 507 Pfam PF02652 L-lactate permease 7 500 3.0E-142 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 NPD12_2042 3290764a07bb29cb6bdb9272787c26cc 426 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 423 5.6E-129 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 NPD12_2042 3290764a07bb29cb6bdb9272787c26cc 426 PIRSF PIRSF001434 1 426 2.7E-122 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 NPD12_2042 3290764a07bb29cb6bdb9272787c26cc 426 Gene3D G3DSA:3.40.640.10 7 288 1.8E-88 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2042 3290764a07bb29cb6bdb9272787c26cc 426 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 423 3.2E-182 T 12-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 NPD12_2042 3290764a07bb29cb6bdb9272787c26cc 426 SUPERFAMILY SSF53383 7 423 6.19E-110 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2042 3290764a07bb29cb6bdb9272787c26cc 426 Gene3D G3DSA:3.90.1150.10 292 426 3.1E-47 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 SMART SM00342 20 103 2.4E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 Gene3D G3DSA:1.10.10.60 57 115 1.6E-15 T 12-10-2018 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 Pfam PF12833 Helix-turn-helix domain 27 104 2.0E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 SUPERFAMILY SSF46689 5 53 5.73E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 SUPERFAMILY SSF46689 56 109 8.51E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 57 99 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 72 87 1.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 87 103 1.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_44 65f847b5c81c72c62a3ee0d4183696d1 129 Gene3D G3DSA:1.10.10.60 2 56 5.1E-14 T 12-10-2018 NPD12_1545 0b93335a8df4dbcfa2327435c6b3fb5d 550 Gene3D G3DSA:3.20.20.370 241 492 2.6E-5 T 12-10-2018 NPD12_1545 0b93335a8df4dbcfa2327435c6b3fb5d 550 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 230 463 6.5E-61 T 12-10-2018 IPR018763 Protein of unknown function DUF2334 NPD12_1545 0b93335a8df4dbcfa2327435c6b3fb5d 550 SUPERFAMILY SSF88713 244 393 9.85E-6 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_3240 fc5eb15ea39227b11816c91f7782daf0 259 Pfam PF00588 SpoU rRNA Methylase family 112 250 1.2E-32 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 NPD12_3240 fc5eb15ea39227b11816c91f7782daf0 259 Gene3D G3DSA:3.30.1330.30 1 100 1.1E-24 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_3240 fc5eb15ea39227b11816c91f7782daf0 259 SMART SM00967 29 104 1.2E-11 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 NPD12_3240 fc5eb15ea39227b11816c91f7782daf0 259 Gene3D G3DSA:3.40.1280.10 108 259 2.8E-49 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal NPD12_3240 fc5eb15ea39227b11816c91f7782daf0 259 SUPERFAMILY SSF75217 107 257 2.35E-38 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases NPD12_3240 fc5eb15ea39227b11816c91f7782daf0 259 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 29 98 6.5E-11 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 NPD12_3240 fc5eb15ea39227b11816c91f7782daf0 259 SUPERFAMILY SSF55315 1 100 5.53E-22 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like NPD12_3102 0183302d0c929e435c1fb4023f18b68d 87 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 16.468 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 NPD12_3102 0183302d0c929e435c1fb4023f18b68d 87 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 2.1E-25 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 NPD12_3102 0183302d0c929e435c1fb4023f18b68d 87 Pfam PF03776 Septum formation topological specificity factor MinE 12 82 2.1E-24 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 NPD12_3102 0183302d0c929e435c1fb4023f18b68d 87 Gene3D G3DSA:3.30.1070.10 1 76 3.6E-19 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 NPD12_3102 0183302d0c929e435c1fb4023f18b68d 87 SUPERFAMILY SSF55229 28 85 1.02E-11 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 NPD12_2284 92e5381bb25e5bb15579f82bf7fcc0f6 255 SMART SM00382 33 221 6.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2284 92e5381bb25e5bb15579f82bf7fcc0f6 255 Pfam PF00005 ABC transporter 25 172 6.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2284 92e5381bb25e5bb15579f82bf7fcc0f6 255 Gene3D G3DSA:3.40.50.300 1 244 3.1E-67 T 12-10-2018 NPD12_2284 92e5381bb25e5bb15579f82bf7fcc0f6 255 SUPERFAMILY SSF52540 4 225 1.21E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1908 c3216ded9122685a69bcb4dbb9e6786b 134 Pfam PF01980 Uncharacterised protein family UPF0066 21 131 1.9E-36 T 12-10-2018 IPR023370 YaeB-like, N-terminal domain NPD12_1908 c3216ded9122685a69bcb4dbb9e6786b 134 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 133 1.1E-40 T 12-10-2018 IPR023370 YaeB-like, N-terminal domain NPD12_1908 c3216ded9122685a69bcb4dbb9e6786b 134 Gene3D G3DSA:2.40.30.70 1 133 9.5E-46 T 12-10-2018 IPR036414 YaeB, N-terminal domain superfamily NPD12_1908 c3216ded9122685a69bcb4dbb9e6786b 134 ProSitePatterns PS01318 TsaA-like domain signature. 81 92 - T 12-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site NPD12_1908 c3216ded9122685a69bcb4dbb9e6786b 134 SUPERFAMILY SSF118196 1 132 5.49E-48 T 12-10-2018 IPR036413 YaeB-like superfamily NPD12_3604 adacec25faabedf98442e98b59b6642a 144 PIRSF PIRSF002181 1 143 4.1E-47 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 NPD12_3604 adacec25faabedf98442e98b59b6642a 144 Gene3D G3DSA:3.90.1180.10 1 142 7.4E-60 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_3604 adacec25faabedf98442e98b59b6642a 144 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 3.2E-59 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3604 adacec25faabedf98442e98b59b6642a 144 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 27.452 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 NPD12_3604 adacec25faabedf98442e98b59b6642a 144 Pfam PF00572 Ribosomal protein L13 14 138 7.5E-56 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 NPD12_3604 adacec25faabedf98442e98b59b6642a 144 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 NPD12_3604 adacec25faabedf98442e98b59b6642a 144 SUPERFAMILY SSF52161 4 142 1.83E-57 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_1576 88aed732cb659c872aa3862071440020 142 SUPERFAMILY SSF54197 6 116 1.27E-34 T 12-10-2018 IPR036265 HIT-like superfamily NPD12_1576 88aed732cb659c872aa3862071440020 142 PRINTS PR00332 Histidine triad family signature 95 105 2.5E-7 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_1576 88aed732cb659c872aa3862071440020 142 PRINTS PR00332 Histidine triad family signature 9 25 2.5E-7 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_1576 88aed732cb659c872aa3862071440020 142 PRINTS PR00332 Histidine triad family signature 30 48 2.5E-7 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_1576 88aed732cb659c872aa3862071440020 142 Gene3D G3DSA:3.30.428.10 1 141 1.5E-37 T 12-10-2018 IPR036265 HIT-like superfamily NPD12_1576 88aed732cb659c872aa3862071440020 142 Pfam PF01230 HIT domain 16 109 1.2E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_3026 4c084f1b6289152402d9febff2b11cda 256 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 170 1.3E-22 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3026 4c084f1b6289152402d9febff2b11cda 256 SUPERFAMILY SSF53187 3 172 3.77E-30 T 12-10-2018 NPD12_3026 4c084f1b6289152402d9febff2b11cda 256 SMART SM00646 67 171 3.4E-12 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3026 4c084f1b6289152402d9febff2b11cda 256 Gene3D G3DSA:2.30.30.40 195 254 5.4E-18 T 12-10-2018 NPD12_3026 4c084f1b6289152402d9febff2b11cda 256 SMART SM00287 195 252 3.2E-8 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_3026 4c084f1b6289152402d9febff2b11cda 256 Pfam PF08239 Bacterial SH3 domain 204 254 2.0E-12 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_3026 4c084f1b6289152402d9febff2b11cda 256 Gene3D G3DSA:3.40.630.40 1 176 1.7E-40 T 12-10-2018 NPD12_3437 577b039e185682c7d040f326a1899c9e 544 SUPERFAMILY SSF55874 405 540 2.49E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_3437 577b039e185682c7d040f326a1899c9e 544 SMART SM00387 437 543 7.0E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_3437 577b039e185682c7d040f326a1899c9e 544 Pfam PF07694 5TMR of 5TMR-LYT 24 188 9.9E-53 T 12-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 NPD12_3437 577b039e185682c7d040f326a1899c9e 544 Pfam PF06580 Histidine kinase 348 426 3.6E-28 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 NPD12_3437 577b039e185682c7d040f326a1899c9e 544 Gene3D G3DSA:1.10.1760.20 29 199 3.6E-5 T 12-10-2018 NPD12_3437 577b039e185682c7d040f326a1899c9e 544 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 446 542 1.7E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase NPD12_3437 577b039e185682c7d040f326a1899c9e 544 Gene3D G3DSA:3.30.565.10 404 543 2.8E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily NPD12_2278 3e66070a3741c956d2314c6a112b0910 81 Gene3D G3DSA:1.10.260.40 4 81 1.1E-8 T 12-10-2018 NPD12_2278 3e66070a3741c956d2314c6a112b0910 81 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 5 66 1.4E-21 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2278 3e66070a3741c956d2314c6a112b0910 81 SUPERFAMILY SSF47413 1 67 6.82E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_2278 3e66070a3741c956d2314c6a112b0910 81 SMART SM00530 5 61 2.4E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_883 344941327901d24e3152ac47673a776e 227 Gene3D G3DSA:3.40.50.300 1 227 7.1E-68 T 12-10-2018 NPD12_883 344941327901d24e3152ac47673a776e 227 SMART SM00382 32 219 1.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_883 344941327901d24e3152ac47673a776e 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_883 344941327901d24e3152ac47673a776e 227 Pfam PF00005 ABC transporter 23 169 2.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_883 344941327901d24e3152ac47673a776e 227 SUPERFAMILY SSF52540 3 225 1.18E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_354 655cc3e6217a3864f428506c76318016 552 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 291 486 8.2E-17 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 NPD12_354 655cc3e6217a3864f428506c76318016 552 Gene3D G3DSA:3.40.50.300 220 493 8.5E-62 T 12-10-2018 NPD12_354 655cc3e6217a3864f428506c76318016 552 SUPERFAMILY SSF55186 69 236 1.06E-34 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 NPD12_354 655cc3e6217a3864f428506c76318016 552 Gene3D G3DSA:3.30.980.10 67 203 4.7E-22 T 12-10-2018 NPD12_354 655cc3e6217a3864f428506c76318016 552 SUPERFAMILY SSF52540 284 484 1.71E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_484 881f58b27ca838584c056a7641b16548 285 Pfam PF02673 Bacitracin resistance protein BacA 11 271 2.2E-77 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 NPD12_484 881f58b27ca838584c056a7641b16548 285 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 6 276 16.967 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 NPD12_484 881f58b27ca838584c056a7641b16548 285 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 11 268 3.2E-72 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 NPD12_2388 3b392e0cbbfec2e0743bc0bc3fc5da9e 138 Pfam PF07485 Domain of Unknown Function (DUF1259) 10 129 3.2E-36 T 12-10-2018 IPR011094 Uncharacterised protein family, LppY/LpqO NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 245 1.4E-93 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 407 426 1.2E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 203 220 1.2E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 26 40 1.2E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 327 339 1.2E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 220 230 1.2E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 150 162 1.2E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 171 188 1.2E-53 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 Gene3D G3DSA:3.40.50.800 368 462 2.5E-32 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 343 3.1E-10 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 SUPERFAMILY SSF55681 6 375 2.87E-128 T 12-10-2018 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 SUPERFAMILY SSF52954 359 461 6.34E-35 T 12-10-2018 NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 Pfam PF03129 Anticodon binding domain 372 459 7.0E-25 T 12-10-2018 IPR004154 Anticodon-binding NPD12_3691 1cd1fe2b5403d020963174beeffa553f 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 4 462 52.375 T 12-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 NPD12_3406 1f3f2a83b57ed6f150052cbe606aff49 144 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 15 142 3.5E-38 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 NPD12_3470 51501246905c603804754fec2ea68fec 311 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3470 51501246905c603804754fec2ea68fec 311 Pfam PF00005 ABC transporter 23 164 1.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3470 51501246905c603804754fec2ea68fec 311 SUPERFAMILY SSF52540 4 223 4.05E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3470 51501246905c603804754fec2ea68fec 311 Gene3D G3DSA:3.40.50.300 1 238 1.9E-59 T 12-10-2018 NPD12_3470 51501246905c603804754fec2ea68fec 311 SMART SM00382 32 213 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2984 5da5bb1ba509092c6f91b7e8804c66da 229 SUPERFAMILY SSF53335 8 132 3.9E-10 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2984 5da5bb1ba509092c6f91b7e8804c66da 229 PIRSF PIRSF018637 1 229 1.5E-70 T 12-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 NPD12_2984 5da5bb1ba509092c6f91b7e8804c66da 229 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 20 223 2.0E-59 T 12-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 NPD12_2984 5da5bb1ba509092c6f91b7e8804c66da 229 Gene3D G3DSA:3.40.50.150 1 160 9.7E-56 T 12-10-2018 NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 Pfam PF00753 Metallo-beta-lactamase superfamily 35 165 3.1E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 Gene3D G3DSA:3.60.15.10 1 248 3.1E-90 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 SMART SM00849 34 220 2.2E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 SUPERFAMILY SSF56281 4 239 6.68E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 PIRSF PIRSF005243 1 389 6.1E-131 T 12-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 Pfam PF00258 Flavodoxin 250 371 8.7E-8 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 SUPERFAMILY SSF52218 247 389 8.12E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2665 61d71e37d335a5bdfda93f09088aec9d 389 Gene3D G3DSA:3.40.50.360 249 389 3.8E-36 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_126 d5740c537aba7596f41f1db17e152907 111 SUPERFAMILY SSF54211 2 110 1.67E-29 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold NPD12_126 d5740c537aba7596f41f1db17e152907 111 Gene3D G3DSA:3.30.230.10 1 111 4.4E-34 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup NPD12_126 d5740c537aba7596f41f1db17e152907 111 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 110 17.047 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 NPD12_126 d5740c537aba7596f41f1db17e152907 111 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 110 4.8E-26 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 NPD12_126 d5740c537aba7596f41f1db17e152907 111 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 6 106 1.0E-20 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 NPD12_126 d5740c537aba7596f41f1db17e152907 111 Pfam PF00825 Ribonuclease P 2 107 1.0E-30 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 NPD12_2039 af92467e407bd543b3267a6f475d78e2 408 Pfam PF05580 SpoIVB peptidase S55 190 399 1.9E-88 T 12-10-2018 IPR008763 Peptidase S55, SpoIVB NPD12_2039 af92467e407bd543b3267a6f475d78e2 408 Gene3D G3DSA:2.30.42.10 124 200 1.2E-16 T 12-10-2018 NPD12_2039 af92467e407bd543b3267a6f475d78e2 408 SUPERFAMILY SSF50156 127 207 9.2E-12 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 NPD12_2039 af92467e407bd543b3267a6f475d78e2 408 SMART SM00228 99 174 0.0017 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_2039 af92467e407bd543b3267a6f475d78e2 408 Pfam PF13180 PDZ domain 125 181 1.8E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 NPD12_2039 af92467e407bd543b3267a6f475d78e2 408 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 4 404 2.8E-158 T 12-10-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B NPD12_3052 bc30a1644ef981fcffd7ef4f10ee85bf 343 Pfam PF04233 Phage Mu protein F like protein 196 301 6.6E-18 T 12-10-2018 IPR006528 Phage head morphogenesis domain NPD12_3052 bc30a1644ef981fcffd7ef4f10ee85bf 343 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 197 304 1.9E-26 T 12-10-2018 IPR006528 Phage head morphogenesis domain NPD12_1465 578b82231e3b49416208d80fb5a02074 366 SUPERFAMILY SSF52540 1 169 1.55E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1465 578b82231e3b49416208d80fb5a02074 366 SUPERFAMILY SSF52540 60 363 1.01E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1465 578b82231e3b49416208d80fb5a02074 366 Pfam PF00176 SNF2 family N-terminal domain 1 187 4.3E-15 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 NPD12_1465 578b82231e3b49416208d80fb5a02074 366 Pfam PF00271 Helicase conserved C-terminal domain 223 325 1.7E-9 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_1465 578b82231e3b49416208d80fb5a02074 366 Gene3D G3DSA:3.40.50.300 184 366 1.2E-29 T 12-10-2018 NPD12_1465 578b82231e3b49416208d80fb5a02074 366 Gene3D G3DSA:3.40.50.10810 1 150 8.2E-20 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily NPD12_146 876c156855b56256f9661da93745ab6e 117 SUPERFAMILY SSF160148 45 116 6.41E-25 T 12-10-2018 IPR036593 CPE0013-like superfamily NPD12_146 876c156855b56256f9661da93745ab6e 117 Pfam PF07892 Protein of unknown function (DUF1667) 34 113 1.0E-25 T 12-10-2018 IPR012460 Protein of unknown function DUF1667 NPD12_146 876c156855b56256f9661da93745ab6e 117 Gene3D G3DSA:3.10.530.10 44 113 4.9E-32 T 12-10-2018 IPR036593 CPE0013-like superfamily NPD12_13 77de965a5ffab599563f78720711d99a 228 Pfam PF00072 Response regulator receiver domain 8 117 5.7E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_13 77de965a5ffab599563f78720711d99a 228 SMART SM00862 151 225 2.5E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_13 77de965a5ffab599563f78720711d99a 228 SMART SM00448 6 116 1.3E-45 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_13 77de965a5ffab599563f78720711d99a 228 SUPERFAMILY SSF52172 7 182 4.39E-45 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_13 77de965a5ffab599563f78720711d99a 228 Gene3D G3DSA:1.10.10.10 134 228 4.5E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_13 77de965a5ffab599563f78720711d99a 228 Gene3D G3DSA:3.40.50.2300 2 133 1.2E-40 T 12-10-2018 NPD12_13 77de965a5ffab599563f78720711d99a 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 3.2E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1463 57efb94a00b6896b9125f505bd4f980c 97 SUPERFAMILY SSF46955 4 53 7.78E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_1874 70ca52e97587a007fd48663229f69fda 331 Gene3D G3DSA:3.30.390.50 243 329 1.7E-26 T 12-10-2018 NPD12_1874 70ca52e97587a007fd48663229f69fda 331 SUPERFAMILY SSF55681 1 242 1.14E-79 T 12-10-2018 NPD12_1874 70ca52e97587a007fd48663229f69fda 331 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 5 319 3.8E-110 T 12-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 NPD12_1874 70ca52e97587a007fd48663229f69fda 331 Gene3D G3DSA:3.30.930.10 1 242 2.0E-82 T 12-10-2018 NPD12_1874 70ca52e97587a007fd48663229f69fda 331 Pfam PF03099 Biotin/lipoate A/B protein ligase family 46 150 4.4E-11 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 NPD12_1874 70ca52e97587a007fd48663229f69fda 331 SUPERFAMILY SSF82649 243 329 4.13E-23 T 12-10-2018 NPD12_1874 70ca52e97587a007fd48663229f69fda 331 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 326 5.3E-25 T 12-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 NPD12_1261 47f7f6a460f7bb1dc29646db7dcf9b91 292 Pfam PF04055 Radical SAM superfamily 9 114 1.6E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_1261 47f7f6a460f7bb1dc29646db7dcf9b91 292 Pfam PF13186 Iron-sulfur cluster-binding domain 219 284 1.7E-11 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_1261 47f7f6a460f7bb1dc29646db7dcf9b91 292 SUPERFAMILY SSF102114 7 287 1.28E-37 T 12-10-2018 NPD12_864 7d2d1e8cfc7bf86dcb75c49208bfee5c 346 Pfam PF01032 FecCD transport family 29 341 5.9E-96 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_864 7d2d1e8cfc7bf86dcb75c49208bfee5c 346 SUPERFAMILY SSF81345 11 341 1.09E-83 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_864 7d2d1e8cfc7bf86dcb75c49208bfee5c 346 Gene3D G3DSA:1.10.3470.10 17 346 1.3E-97 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_2871 7eaf25c5384ead2d3fdf92710e7ebe58 160 Pfam PF01475 Ferric uptake regulator family 15 148 1.7E-19 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 NPD12_2871 7eaf25c5384ead2d3fdf92710e7ebe58 160 SUPERFAMILY SSF46785 10 152 7.14E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2871 7eaf25c5384ead2d3fdf92710e7ebe58 160 Gene3D G3DSA:1.10.10.10 3 87 6.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2871 7eaf25c5384ead2d3fdf92710e7ebe58 160 Gene3D G3DSA:3.30.1490.190 98 160 5.0E-14 T 12-10-2018 NPD12_2943 312b0cb5e62f3e481a1b640c11e65e40 204 Pfam PF12804 MobA-like NTP transferase domain 4 160 1.0E-33 T 12-10-2018 IPR025877 MobA-like NTP transferase NPD12_2943 312b0cb5e62f3e481a1b640c11e65e40 204 TIGRFAM TIGR03310 matur_MocA_YgfJ: molybdenum cofactor cytidylyltransferase 3 186 3.2E-68 T 12-10-2018 IPR017696 Molybdenum cofactor cytidylyltransferase KEGG: 00790+2.7.7.76|MetaCyc: PWY-6476 NPD12_2943 312b0cb5e62f3e481a1b640c11e65e40 204 SUPERFAMILY SSF53448 1 185 9.1E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2943 312b0cb5e62f3e481a1b640c11e65e40 204 Gene3D G3DSA:3.90.550.10 1 193 1.4E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_915 3e92b079f72a67dd39eb8367c54b8840 208 Pfam PF08241 Methyltransferase domain 43 138 4.4E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 NPD12_915 3e92b079f72a67dd39eb8367c54b8840 208 SUPERFAMILY SSF53335 5 183 2.32E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_915 3e92b079f72a67dd39eb8367c54b8840 208 Gene3D G3DSA:3.40.50.150 2 190 6.0E-34 T 12-10-2018 NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 SUPERFAMILY SSF52540 322 564 3.48E-92 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 Pfam PF00005 ABC transporter 348 497 4.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 SMART SM00382 357 549 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 Gene3D G3DSA:1.20.1560.10 1 315 1.6E-76 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 Gene3D G3DSA:3.40.50.300 323 571 1.8E-91 T 12-10-2018 NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 Pfam PF00664 ABC transporter transmembrane region 19 286 1.2E-40 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 NPD12_1555 2c99eb905270734fdef4978e5e758a77 572 SUPERFAMILY SSF90123 3 317 1.01E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1162 43f5ab913166059873d0afb41a4492eb 154 SUPERFAMILY SSF50475 1 153 2.29E-50 T 12-10-2018 NPD12_1162 43f5ab913166059873d0afb41a4492eb 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 14 152 1.5E-19 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related NPD12_1162 43f5ab913166059873d0afb41a4492eb 154 Gene3D G3DSA:2.30.110.10 2 153 1.4E-42 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_1558 8532e31fcdb55a36689bae99b2efade9 230 Pfam PF00072 Response regulator receiver domain 4 113 1.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1558 8532e31fcdb55a36689bae99b2efade9 230 SUPERFAMILY SSF52172 1 177 1.27E-36 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_1558 8532e31fcdb55a36689bae99b2efade9 230 SMART SM00448 2 112 1.3E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1558 8532e31fcdb55a36689bae99b2efade9 230 Gene3D G3DSA:3.40.50.2300 1 122 3.5E-35 T 12-10-2018 NPD12_1558 8532e31fcdb55a36689bae99b2efade9 230 SMART SM00862 146 223 4.4E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_1558 8532e31fcdb55a36689bae99b2efade9 230 Gene3D G3DSA:1.10.10.10 126 229 8.9E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1558 8532e31fcdb55a36689bae99b2efade9 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 222 2.0E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_3177 c2c4cff4d8b79bf38f00ab5004f9c175 376 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 2 372 3.2E-154 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 NPD12_3177 c2c4cff4d8b79bf38f00ab5004f9c175 376 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 2 371 3.4E-148 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 NPD12_3177 c2c4cff4d8b79bf38f00ab5004f9c175 376 SUPERFAMILY SSF51713 1 370 1.14E-150 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 NPD12_3177 c2c4cff4d8b79bf38f00ab5004f9c175 376 Gene3D G3DSA:3.20.20.105 1 375 7.3E-163 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 NPD12_3177 c2c4cff4d8b79bf38f00ab5004f9c175 376 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 371 53.621 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 NPD12_3177 c2c4cff4d8b79bf38f00ab5004f9c175 376 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 367 3.6E-88 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 NPD12_817 4d81507687ccc36ba675f1f71f5f5891 162 Pfam PF02915 Rubrerythrin 9 146 3.1E-17 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 NPD12_817 4d81507687ccc36ba675f1f71f5f5891 162 SUPERFAMILY SSF47240 6 153 1.15E-25 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_817 4d81507687ccc36ba675f1f71f5f5891 162 Gene3D G3DSA:1.20.1260.10 2 150 2.2E-28 T 12-10-2018 IPR012347 Ferritin-like NPD12_1935 a88caee0005b4696a09bca5f83919bfa 309 Gene3D G3DSA:4.10.80.30 203 225 1.1E-38 T 12-10-2018 NPD12_1935 a88caee0005b4696a09bca5f83919bfa 309 Gene3D G3DSA:1.10.530.10 150 296 1.1E-38 T 12-10-2018 NPD12_1935 a88caee0005b4696a09bca5f83919bfa 309 SMART SM00047 134 299 2.3E-22 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 NPD12_1935 a88caee0005b4696a09bca5f83919bfa 309 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 158 295 1.1E-19 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 NPD12_601 72d82e66ca62b69c6e9cd3fd9783ff65 223 Gene3D G3DSA:3.40.50.300 15 222 2.6E-62 T 12-10-2018 NPD12_601 72d82e66ca62b69c6e9cd3fd9783ff65 223 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 6 217 1.8E-75 T 12-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 NPD12_601 72d82e66ca62b69c6e9cd3fd9783ff65 223 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 36 196 1.5E-25 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain NPD12_601 72d82e66ca62b69c6e9cd3fd9783ff65 223 PIRSF PIRSF005624 2 223 3.2E-82 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 NPD12_601 72d82e66ca62b69c6e9cd3fd9783ff65 223 SUPERFAMILY SSF52540 5 222 1.97E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1740 978a3fb5244013b2ef464b1cacf68dfa 576 Pfam PF14574 Domain of unknown function (DUF4445) 176 574 4.3E-140 T 12-10-2018 IPR027980 Protein of unknown function DUF4445 NPD12_1740 978a3fb5244013b2ef464b1cacf68dfa 576 SUPERFAMILY SSF54292 2 87 8.52E-17 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 NPD12_1740 978a3fb5244013b2ef464b1cacf68dfa 576 Gene3D G3DSA:3.10.20.30 4 89 9.2E-17 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_1740 978a3fb5244013b2ef464b1cacf68dfa 576 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 77 2.5E-7 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 NPD12_1740 978a3fb5244013b2ef464b1cacf68dfa 576 Gene3D G3DSA:3.30.420.480 173 353 4.8E-55 T 12-10-2018 NPD12_1667 207440670aec4997ab7e653c0858811b 245 PIRSF PIRSF039085 1 244 4.7E-109 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 NPD12_1667 207440670aec4997ab7e653c0858811b 245 SUPERFAMILY SSF52540 1 237 1.22E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1667 207440670aec4997ab7e653c0858811b 245 SMART SM00382 26 216 9.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1667 207440670aec4997ab7e653c0858811b 245 Gene3D G3DSA:3.40.50.300 1 245 1.6E-76 T 12-10-2018 NPD12_1667 207440670aec4997ab7e653c0858811b 245 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1667 207440670aec4997ab7e653c0858811b 245 Pfam PF00005 ABC transporter 17 168 5.3E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_562 54cb57b13a3c20d0505ecbdae3aa1775 350 TIGRFAM TIGR00277 HDIG: HDIG domain 152 218 2.1E-7 T 12-10-2018 IPR006675 HDIG domain NPD12_562 54cb57b13a3c20d0505ecbdae3aa1775 350 Gene3D G3DSA:1.10.3210.10 5 291 5.9E-75 T 12-10-2018 NPD12_562 54cb57b13a3c20d0505ecbdae3aa1775 350 Pfam PF01966 HD domain 127 249 1.6E-17 T 12-10-2018 IPR006674 HD domain NPD12_562 54cb57b13a3c20d0505ecbdae3aa1775 350 SUPERFAMILY SSF109604 118 287 3.93E-34 T 12-10-2018 NPD12_562 54cb57b13a3c20d0505ecbdae3aa1775 350 SMART SM00471 123 259 2.4E-10 T 12-10-2018 IPR003607 HD/PDEase domain NPD12_3550 e42000703743bc3ee12309bf7fb00835 274 SUPERFAMILY SSF52518 3 266 6.7E-96 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_3550 e42000703743bc3ee12309bf7fb00835 274 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 10 267 2.3E-64 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 NPD12_3550 e42000703743bc3ee12309bf7fb00835 274 Gene3D G3DSA:3.40.50.970 1 274 1.8E-116 T 12-10-2018 NPD12_3550 e42000703743bc3ee12309bf7fb00835 274 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Gene3D G3DSA:3.80.10.10 1415 1620 9.3E-25 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Pfam PF04122 Putative cell wall binding repeat 2 239 329 5.7E-14 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Pfam PF04122 Putative cell wall binding repeat 2 137 227 5.6E-13 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Pfam PF04122 Putative cell wall binding repeat 2 39 123 4.1E-17 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Pfam PF13306 Leucine rich repeats (6 copies) 999 1107 7.3E-24 T 12-10-2018 IPR026906 Leucine rich repeat 5 NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Pfam PF13306 Leucine rich repeats (6 copies) 1472 1598 9.1E-21 T 12-10-2018 IPR026906 Leucine rich repeat 5 NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Pfam PF13306 Leucine rich repeats (6 copies) 605 727 2.0E-29 T 12-10-2018 IPR026906 Leucine rich repeat 5 NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Gene3D G3DSA:3.80.10.10 1123 1403 1.4E-21 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Gene3D G3DSA:3.80.10.10 556 895 1.6E-44 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Gene3D G3DSA:3.80.10.10 912 1122 6.6E-31 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily NPD12_545 cdf9bf38127c8a59e4a95209ee7be263 1634 Gene3D G3DSA:3.40.50.12090 58 154 3.4E-11 T 12-10-2018 NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 219 229 - T 12-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 SMART SM01301 106 239 3.2E-54 T 12-10-2018 NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 SUPERFAMILY SSF52799 27 303 5.52E-36 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 Gene3D G3DSA:3.90.190.10 30 307 7.2E-84 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 Pfam PF14323 GxGYxYP putative glycoside hydrolase C-terminal domain 578 814 1.4E-82 T 12-10-2018 IPR025832 GxGYxYP putative glycoside hydrolase, C-terminal NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 Gene3D G3DSA:3.20.20.490 563 820 3.8E-89 T 12-10-2018 IPR038410 GxGYxYP putative glycoside hydrolase, C-terminal domain superfamily NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 Pfam PF16216 GxGYxY sequence motif in domain of unknown function N-terminal 347 559 1.2E-74 T 12-10-2018 IPR032626 GxGYxYP putative glycoside hydrolase, N-terminal NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 Pfam PF14566 Inositol hexakisphosphate 106 239 2.1E-25 T 12-10-2018 NPD12_2339 5c53533ac57af89f56605ea2ec59c9c8 820 ProDom PD069361 HYDROLASE VIRULENCE PLASMID AVRBS1.1 HEXAPHOSPHATE TYROSINE PHOSPHOHYDROLASE PRECURSOR MYO-INOSITOL AVIRULENCE 209 297 4.0E-12 T 12-10-2018 NPD12_3552 38342c589751aa21802d9c8a4924f58e 107 SUPERFAMILY SSF47598 5 46 5.56E-5 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 NPD12_3552 38342c589751aa21802d9c8a4924f58e 107 Gene3D G3DSA:1.10.1220.10 1 89 1.6E-21 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 NPD12_2629 2b42b61a4f1237abbb604a785ff3b5f5 91 Gene3D G3DSA:1.10.1200.10 1 84 3.6E-9 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2629 2b42b61a4f1237abbb604a785ff3b5f5 91 Pfam PF00550 Phosphopantetheine attachment site 13 77 1.8E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain NPD12_2629 2b42b61a4f1237abbb604a785ff3b5f5 91 SUPERFAMILY SSF47336 11 81 5.1E-11 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_1117 d38432900c303f7de864f2e2f2cd2876 233 Gene3D G3DSA:1.10.3290.10 1 233 9.0E-69 T 12-10-2018 IPR036597 Fido-like domain superfamily NPD12_1117 d38432900c303f7de864f2e2f2cd2876 233 SUPERFAMILY SSF140931 59 219 1.7E-37 T 12-10-2018 IPR036597 Fido-like domain superfamily NPD12_1117 d38432900c303f7de864f2e2f2cd2876 233 Pfam PF02661 Fic/DOC family 82 180 6.1E-21 T 12-10-2018 IPR003812 Fido domain NPD12_2602 4030668d68451dc551a707dae11c55ff 218 Gene3D G3DSA:3.40.50.150 3 218 5.5E-60 T 12-10-2018 NPD12_2602 4030668d68451dc551a707dae11c55ff 218 Pfam PF01596 O-methyltransferase 18 213 8.8E-35 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 NPD12_2602 4030668d68451dc551a707dae11c55ff 218 SUPERFAMILY SSF53335 31 215 7.17E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_563 ebc05decf7c1475b77f4b6a1a5927bbf 340 Gene3D G3DSA:1.20.1540.10 147 340 1.5E-46 T 12-10-2018 IPR035952 Rhomboid-like superfamily NPD12_563 ebc05decf7c1475b77f4b6a1a5927bbf 340 Pfam PF01694 Rhomboid family 198 335 5.7E-36 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 NPD12_563 ebc05decf7c1475b77f4b6a1a5927bbf 340 SUPERFAMILY SSF144091 151 338 6.93E-46 T 12-10-2018 NPD12_2175 e78c53f0c79aa27a489fda7062189b72 240 Pfam PF00005 ABC transporter 17 165 6.5E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2175 e78c53f0c79aa27a489fda7062189b72 240 SUPERFAMILY SSF52540 1 235 1.73E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2175 e78c53f0c79aa27a489fda7062189b72 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2175 e78c53f0c79aa27a489fda7062189b72 240 PIRSF PIRSF039085 1 240 2.5E-119 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 NPD12_2175 e78c53f0c79aa27a489fda7062189b72 240 SMART SM00382 26 213 2.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2175 e78c53f0c79aa27a489fda7062189b72 240 Gene3D G3DSA:3.40.50.300 1 240 1.4E-79 T 12-10-2018 NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 SMART SM00729 299 550 1.5E-12 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 SUPERFAMILY SSF102114 297 548 1.06E-14 T 12-10-2018 NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 6 564 1.6E-273 T 12-10-2018 IPR022946 Uncharacterised protein family UPF0313 NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 6 565 53.941 T 12-10-2018 IPR022946 Uncharacterised protein family UPF0313 NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 Pfam PF11842 Domain of unknown function (DUF3362) 518 641 2.9E-35 T 12-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 Pfam PF04055 Radical SAM superfamily 304 502 5.1E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 Pfam PF08497 Radical SAM N-terminal 6 302 1.8E-136 T 12-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal NPD12_360 9eebd44b2a3f70554f32fcd7b9dfcc2e 645 Gene3D G3DSA:3.80.30.20 299 568 2.0E-13 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_2603 5284608881edeef1227f4ff885401c50 343 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 4 339 1.0E-75 T 12-10-2018 IPR003770 Endolytic murein transglycosylase NPD12_2603 5284608881edeef1227f4ff885401c50 343 Gene3D G3DSA:1.10.8.1150 114 198 6.2E-6 T 12-10-2018 NPD12_2603 5284608881edeef1227f4ff885401c50 343 Gene3D G3DSA:1.10.8.1150 42 113 2.4E-5 T 12-10-2018 NPD12_2603 5284608881edeef1227f4ff885401c50 343 Pfam PF02618 YceG-like family 47 337 3.7E-76 T 12-10-2018 IPR003770 Endolytic murein transglycosylase NPD12_2603 5284608881edeef1227f4ff885401c50 343 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 8 342 30.265 T 12-10-2018 IPR003770 Endolytic murein transglycosylase NPD12_1768 b360870d651ffe327434a2a073a29930 690 SMART SM00304 330 385 3.2E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_1768 b360870d651ffe327434a2a073a29930 690 Gene3D G3DSA:1.10.287.950 382 689 7.1E-64 T 12-10-2018 NPD12_1768 b360870d651ffe327434a2a073a29930 690 Pfam PF02743 Cache domain 37 292 1.1E-30 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_1768 b360870d651ffe327434a2a073a29930 690 SUPERFAMILY SSF103190 143 211 3.4E-5 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_1768 b360870d651ffe327434a2a073a29930 690 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 467 637 2.5E-39 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1768 b360870d651ffe327434a2a073a29930 690 Gene3D G3DSA:3.30.450.20 203 301 1.1E-34 T 12-10-2018 NPD12_1768 b360870d651ffe327434a2a073a29930 690 Gene3D G3DSA:3.30.450.20 110 202 1.1E-34 T 12-10-2018 NPD12_1768 b360870d651ffe327434a2a073a29930 690 SMART SM00283 414 689 2.4E-60 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_1768 b360870d651ffe327434a2a073a29930 690 Gene3D G3DSA:1.10.8.500 329 381 6.7E-7 T 12-10-2018 NPD12_1768 b360870d651ffe327434a2a073a29930 690 SUPERFAMILY SSF58104 360 689 5.23E-65 T 12-10-2018 NPD12_3047 695eaffe4f247d7d04fb96d8e800f24d 114 Pfam PF05135 Phage gp6-like head-tail connector protein 2 100 3.0E-8 T 12-10-2018 IPR021146 Phage gp6-like head-tail connector protein NPD12_2606 0db2635382de31042b5f1115039e5f37 150 Gene3D G3DSA:3.30.1490.190 96 150 1.5E-21 T 12-10-2018 NPD12_2606 0db2635382de31042b5f1115039e5f37 150 Pfam PF01475 Ferric uptake regulator family 19 141 3.5E-40 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 NPD12_2606 0db2635382de31042b5f1115039e5f37 150 Gene3D G3DSA:1.10.10.10 3 92 1.2E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2606 0db2635382de31042b5f1115039e5f37 150 SUPERFAMILY SSF46785 10 145 9.49E-43 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_973 88e82549bc979b2c1bb133218aaa7dd5 213 Pfam PF02589 LUD domain 14 207 3.6E-61 T 12-10-2018 IPR003741 LUD domain NPD12_973 88e82549bc979b2c1bb133218aaa7dd5 213 SUPERFAMILY SSF100950 13 153 4.39E-5 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_973 88e82549bc979b2c1bb133218aaa7dd5 213 PIRSF PIRSF020269 1 213 1.6E-88 T 12-10-2018 IPR009501 Uncharacterised conserved protein UCP020269 NPD12_540 1fcf8310722d19de0552b444f3b8406c 130 Pfam PF07009 NusG domain II 12 121 6.8E-34 T 12-10-2018 IPR024045 NusG, domain 2 NPD12_540 1fcf8310722d19de0552b444f3b8406c 130 Gene3D G3DSA:2.60.320.10 30 128 2.2E-31 T 12-10-2018 IPR038690 NusG, domain 2 superfamily NPD12_2408 19652257d3483c0bdda232a064bcb958 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 3.5E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2408 19652257d3483c0bdda232a064bcb958 235 Gene3D G3DSA:3.40.50.2300 1 131 7.0E-39 T 12-10-2018 NPD12_2408 19652257d3483c0bdda232a064bcb958 235 Gene3D G3DSA:1.10.10.10 132 235 5.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2408 19652257d3483c0bdda232a064bcb958 235 SUPERFAMILY SSF52172 2 130 1.42E-40 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2408 19652257d3483c0bdda232a064bcb958 235 Pfam PF00072 Response regulator receiver domain 6 115 1.7E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2408 19652257d3483c0bdda232a064bcb958 235 SMART SM00862 154 230 1.7E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_2408 19652257d3483c0bdda232a064bcb958 235 SMART SM00448 4 114 5.3E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2408 19652257d3483c0bdda232a064bcb958 235 SUPERFAMILY SSF46894 132 231 4.25E-31 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_2442 8e78eed08205d9a4a4480d84d839ba60 425 Gene3D G3DSA:3.50.50.60 185 423 1.2E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2442 8e78eed08205d9a4a4480d84d839ba60 425 Pfam PF01134 Glucose inhibited division protein A 265 351 1.0E-13 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 NPD12_2442 8e78eed08205d9a4a4480d84d839ba60 425 Pfam PF01134 Glucose inhibited division protein A 2 220 1.9E-28 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 NPD12_2442 8e78eed08205d9a4a4480d84d839ba60 425 Gene3D G3DSA:3.50.50.60 1 183 1.3E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2442 8e78eed08205d9a4a4480d84d839ba60 425 SUPERFAMILY SSF51905 2 347 2.15E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3324 3cf3de18ebe18d08fc1ee728e612f92e 181 SUPERFAMILY SSF57802 1 48 1.68E-11 T 12-10-2018 NPD12_3324 3cf3de18ebe18d08fc1ee728e612f92e 181 SUPERFAMILY SSF47240 55 180 9.14E-33 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_3324 3cf3de18ebe18d08fc1ee728e612f92e 181 Gene3D G3DSA:1.20.1260.10 55 179 4.1E-24 T 12-10-2018 IPR012347 Ferritin-like NPD12_3324 3cf3de18ebe18d08fc1ee728e612f92e 181 Pfam PF02915 Rubrerythrin 62 175 1.6E-14 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 NPD12_3324 3cf3de18ebe18d08fc1ee728e612f92e 181 Gene3D G3DSA:2.20.28.10 1 35 2.0E-12 T 12-10-2018 NPD12_267 38915dfad1ef6d93c4f84306636b59bb 337 SUPERFAMILY SSF56112 18 334 3.7E-46 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_267 38915dfad1ef6d93c4f84306636b59bb 337 Gene3D G3DSA:3.90.1200.10 101 332 2.8E-66 T 12-10-2018 NPD12_267 38915dfad1ef6d93c4f84306636b59bb 337 Pfam PF01633 Choline/ethanolamine kinase 149 252 1.4E-8 T 12-10-2018 NPD12_267 38915dfad1ef6d93c4f84306636b59bb 337 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 26 332 5.0E-95 T 12-10-2018 IPR014255 Spore coat protein CotS NPD12_267 38915dfad1ef6d93c4f84306636b59bb 337 Gene3D G3DSA:3.30.200.20 1 100 2.6E-18 T 12-10-2018 NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 Pfam PF01842 ACT domain 151 211 9.3E-10 T 12-10-2018 IPR002912 ACT domain NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 208 7.9E-72 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 Gene3D G3DSA:3.30.70.260 149 222 1.1E-16 T 12-10-2018 NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 SUPERFAMILY SSF55021 140 220 1.53E-17 T 12-10-2018 NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 SUPERFAMILY SSF143548 19 138 8.89E-32 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 Pfam PF03315 Serine dehydratase beta chain 5 75 6.8E-13 T 12-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 Gene3D G3DSA:3.30.1330.90 13 91 1.2E-19 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 NPD12_1399 f6572b0372c1ce3f23988b9f49a9cdfc 224 PIRSF PIRSF036692 1 222 3.7E-93 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 NPD12_3269 43d8391a6b2c61fd448b8baf1551e0f4 232 Gene3D G3DSA:2.40.50.140 100 202 1.2E-23 T 12-10-2018 NPD12_3269 43d8391a6b2c61fd448b8baf1551e0f4 232 Gene3D G3DSA:2.40.50.140 1 99 1.3E-20 T 12-10-2018 NPD12_3269 43d8391a6b2c61fd448b8baf1551e0f4 232 SUPERFAMILY SSF50249 8 204 2.57E-40 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3269 43d8391a6b2c61fd448b8baf1551e0f4 232 Pfam PF00436 Single-strand binding protein family 107 195 6.0E-16 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 NPD12_3269 43d8391a6b2c61fd448b8baf1551e0f4 232 Pfam PF00436 Single-strand binding protein family 8 97 9.6E-5 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 NPD12_1810 e8356754e2623d5281fd4229c34936dd 242 Pfam PF00977 Histidine biosynthesis protein 3 227 7.9E-75 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 NPD12_1810 e8356754e2623d5281fd4229c34936dd 242 Gene3D G3DSA:3.20.20.70 2 241 5.2E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1810 e8356754e2623d5281fd4229c34936dd 242 SUPERFAMILY SSF51366 1 236 5.18E-71 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 NPD12_1810 e8356754e2623d5281fd4229c34936dd 242 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 232 1.6E-85 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 NPD12_1810 e8356754e2623d5281fd4229c34936dd 242 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 235 35.987 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 NPD12_301 eb24a47ccd1ee923d7b477c0c4087c43 162 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 134 2.1E-18 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain NPD12_301 eb24a47ccd1ee923d7b477c0c4087c43 162 PIRSF PIRSF006019 1 161 1.0E-35 T 12-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 NPD12_301 eb24a47ccd1ee923d7b477c0c4087c43 162 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 79 124 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 NPD12_301 eb24a47ccd1ee923d7b477c0c4087c43 162 SUPERFAMILY SSF53927 8 140 2.58E-25 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_301 eb24a47ccd1ee923d7b477c0c4087c43 162 Gene3D G3DSA:3.40.140.10 1 156 1.5E-31 T 12-10-2018 NPD12_119 e7b69d28e4c44cd2936321f7eec9d712 259 Gene3D G3DSA:1.10.10.2830 83 197 1.9E-34 T 12-10-2018 NPD12_119 e7b69d28e4c44cd2936321f7eec9d712 259 Gene3D G3DSA:3.90.1530.30 19 82 1.9E-26 T 12-10-2018 NPD12_119 e7b69d28e4c44cd2936321f7eec9d712 259 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 2 181 1.3E-54 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 NPD12_119 e7b69d28e4c44cd2936321f7eec9d712 259 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 5 258 7.5E-96 T 12-10-2018 IPR023705 Nucleoid occlusion protein NPD12_119 e7b69d28e4c44cd2936321f7eec9d712 259 Pfam PF02195 ParB-like nuclease domain 7 95 7.0E-25 T 12-10-2018 IPR003115 ParB/Sulfiredoxin NPD12_119 e7b69d28e4c44cd2936321f7eec9d712 259 SUPERFAMILY SSF110849 5 137 3.82E-33 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily NPD12_119 e7b69d28e4c44cd2936321f7eec9d712 259 SMART SM00470 6 96 5.8E-31 T 12-10-2018 IPR003115 ParB/Sulfiredoxin NPD12_279 2af40a3ab31208ab9d7ee8d5c86119ad 393 Gene3D G3DSA:3.30.300.210 242 393 2.8E-34 T 12-10-2018 IPR038501 Spore germination GerAC superfamily NPD12_279 2af40a3ab31208ab9d7ee8d5c86119ad 393 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 392 7.5E-109 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 NPD12_279 2af40a3ab31208ab9d7ee8d5c86119ad 393 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 228 390 3.7E-32 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 NPD12_3358 b55ccedb1bdc1a3d92520a884e7c7652 252 SMART SM00382 31 211 4.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3358 b55ccedb1bdc1a3d92520a884e7c7652 252 Pfam PF00005 ABC transporter 22 161 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3358 b55ccedb1bdc1a3d92520a884e7c7652 252 SUPERFAMILY SSF52540 3 235 9.94E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3358 b55ccedb1bdc1a3d92520a884e7c7652 252 Gene3D G3DSA:3.40.50.300 2 245 2.2E-63 T 12-10-2018 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 Gene3D G3DSA:1.20.1250.20 237 438 3.5E-54 T 12-10-2018 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 ProSitePatterns PS00942 glpT family of transporters signature. 150 166 - T 12-10-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site Reactome: R-HSA-3229133|Reactome: R-HSA-70263 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 PIRSF PIRSF002808 6 444 1.7E-162 T 12-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 Pfam PF07690 Major Facilitator Superfamily 36 391 1.7E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 4 434 6.7E-198 T 12-10-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 412 8.0E-147 T 12-10-2018 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 Gene3D G3DSA:1.20.1250.20 19 223 6.4E-56 T 12-10-2018 NPD12_1265 ee4ecc737136a584ec3ba45032bcb091 445 SUPERFAMILY SSF103473 10 436 4.05E-83 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_650 2190648f3cbaad34c336b456f8fcd85d 458 Gene3D G3DSA:3.40.50.300 232 456 5.2E-69 T 12-10-2018 NPD12_650 2190648f3cbaad34c336b456f8fcd85d 458 Gene3D G3DSA:3.40.50.1010 2 144 8.4E-21 T 12-10-2018 NPD12_650 2190648f3cbaad34c336b456f8fcd85d 458 SUPERFAMILY SSF52540 125 417 3.44E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_650 2190648f3cbaad34c336b456f8fcd85d 458 SMART SM00670 3 128 6.3E-9 T 12-10-2018 IPR002716 PIN domain NPD12_650 2190648f3cbaad34c336b456f8fcd85d 458 Pfam PF13638 PIN domain 5 140 1.3E-33 T 12-10-2018 IPR002716 PIN domain NPD12_650 2190648f3cbaad34c336b456f8fcd85d 458 Pfam PF02562 PhoH-like protein 234 451 1.4E-50 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 NPD12_650 2190648f3cbaad34c336b456f8fcd85d 458 SUPERFAMILY SSF88723 3 144 2.75E-13 T 12-10-2018 IPR029060 PIN-like domain superfamily NPD12_3729 e099dfd54fdbde2c8d189824f550a6bf 136 Gene3D G3DSA:1.10.10.1400 1 67 5.7E-18 T 12-10-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily NPD12_3729 e099dfd54fdbde2c8d189824f550a6bf 136 Pfam PF03592 Terminase small subunit 5 118 3.1E-30 T 12-10-2018 IPR005335 Terminase small subunit GO:0006323 NPD12_3222 be578ad84211d8b08bf72ecfedc624fd 298 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 263 5.1E-126 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 NPD12_3222 be578ad84211d8b08bf72ecfedc624fd 298 Gene3D G3DSA:3.90.550.10 1 290 3.0E-95 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_3222 be578ad84211d8b08bf72ecfedc624fd 298 SUPERFAMILY SSF53448 1 276 3.55E-69 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_3222 be578ad84211d8b08bf72ecfedc624fd 298 Pfam PF00483 Nucleotidyl transferase 5 266 1.1E-33 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 NPD12_1716 9c5c327fb2168312d75d67ea6f063194 150 Hamap MF_01197 Cell division protein SepF [sepF]. 3 139 17.717 T 12-10-2018 IPR023052 Cell division protein SepF GO:0090529 NPD12_1716 9c5c327fb2168312d75d67ea6f063194 150 Pfam PF04472 Cell division protein SepF 60 131 2.0E-24 T 12-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 NPD12_1716 9c5c327fb2168312d75d67ea6f063194 150 Gene3D G3DSA:3.30.110.150 55 148 2.3E-26 T 12-10-2018 IPR038594 SepF-like superfamily NPD12_1561 3520a41cfb1ea4a3152322bf743d69b7 200 Pfam PF02687 FtsX-like permease family 100 192 4.3E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_278 7bf47e8fe27a909988b9974b68f76803 365 SUPERFAMILY SSF81343 38 130 3.27E-6 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 NPD12_278 7bf47e8fe27a909988b9974b68f76803 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 361 6.8E-66 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_278 7bf47e8fe27a909988b9974b68f76803 365 Pfam PF03845 Spore germination protein 9 325 2.1E-55 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_668 f5f8037bac0d002be7d81ca4b3a0274c 164 Pfam PF00578 AhpC/TSA family 19 140 2.3E-20 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 NPD12_668 f5f8037bac0d002be7d81ca4b3a0274c 164 Gene3D G3DSA:3.40.30.10 1 163 3.7E-49 T 12-10-2018 NPD12_668 f5f8037bac0d002be7d81ca4b3a0274c 164 ProSitePatterns PS01265 Tpx family signature. 81 92 - T 12-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 NPD12_668 f5f8037bac0d002be7d81ca4b3a0274c 164 Hamap MF_00269 Thiol peroxidase [tpx]. 2 161 34.959 T 12-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 NPD12_668 f5f8037bac0d002be7d81ca4b3a0274c 164 SUPERFAMILY SSF52833 3 158 1.54E-40 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_1806 8162922957f06b9103498ba948b0c2de 212 Gene3D G3DSA:3.40.190.10 96 179 2.8E-76 T 12-10-2018 NPD12_1806 8162922957f06b9103498ba948b0c2de 212 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 187 1.2E-62 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 NPD12_1806 8162922957f06b9103498ba948b0c2de 212 Gene3D G3DSA:3.40.190.10 6 201 2.8E-76 T 12-10-2018 NPD12_1806 8162922957f06b9103498ba948b0c2de 212 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 146 167 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 NPD12_1806 8162922957f06b9103498ba948b0c2de 212 SUPERFAMILY SSF53850 3 210 1.34E-66 T 12-10-2018 NPD12_1806 8162922957f06b9103498ba948b0c2de 212 Pfam PF01634 ATP phosphoribosyltransferase 55 206 8.6E-54 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 NPD12_1806 8162922957f06b9103498ba948b0c2de 212 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 211 56.477 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 NPD12_1890 8e143ba7b5f40ca7148f18b3ae1af024 53 Gene3D G3DSA:3.30.160.160 5 47 1.4E-11 T 12-10-2018 NPD12_1890 8e143ba7b5f40ca7148f18b3ae1af024 53 Pfam PF07411 Domain of unknown function (DUF1508) 13 42 4.8E-6 T 12-10-2018 IPR010879 Domain of unknown function DUF1508 NPD12_1890 8e143ba7b5f40ca7148f18b3ae1af024 53 SUPERFAMILY SSF160113 6 45 7.33E-10 T 12-10-2018 IPR036913 YegP-like superfamily NPD12_1460 0d423a864207f9dbe5b91e8ebfb86d04 67 SUPERFAMILY SSF47413 3 63 1.1E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1460 0d423a864207f9dbe5b91e8ebfb86d04 67 SMART SM00530 6 61 3.9E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1460 0d423a864207f9dbe5b91e8ebfb86d04 67 Pfam PF01381 Helix-turn-helix 7 61 2.1E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1460 0d423a864207f9dbe5b91e8ebfb86d04 67 Gene3D G3DSA:1.10.260.40 2 66 2.1E-19 T 12-10-2018 NPD12_2149 d354a159b80a1df9050f5f275a43b946 475 Pfam PF02378 Phosphotransferase system, EIIC 111 409 9.4E-36 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_2149 d354a159b80a1df9050f5f275a43b946 475 Pfam PF00367 phosphotransferase system, EIIB 9 42 2.1E-13 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_2149 d354a159b80a1df9050f5f275a43b946 475 Gene3D G3DSA:3.30.1360.60 1 77 9.0E-24 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_2149 d354a159b80a1df9050f5f275a43b946 475 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_2149 d354a159b80a1df9050f5f275a43b946 475 SUPERFAMILY SSF55604 8 81 5.49E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_2149 d354a159b80a1df9050f5f275a43b946 475 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 466 1.3E-211 T 12-10-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 NPD12_1368 48f6513bdbcad9415d0986eabd432d55 274 SMART SM00062 39 267 5.5E-64 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_1368 48f6513bdbcad9415d0986eabd432d55 274 Gene3D G3DSA:3.40.190.10 108 228 7.7E-64 T 12-10-2018 NPD12_1368 48f6513bdbcad9415d0986eabd432d55 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 266 9.2E-60 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_1368 48f6513bdbcad9415d0986eabd432d55 274 SUPERFAMILY SSF53850 8 267 1.98E-64 T 12-10-2018 NPD12_1368 48f6513bdbcad9415d0986eabd432d55 274 Gene3D G3DSA:3.40.190.10 41 265 7.7E-64 T 12-10-2018 NPD12_342 66acef9fcfdf7dde3ba7d402c575c21d 262 SMART SM00954 45 166 5.8E-41 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 NPD12_342 66acef9fcfdf7dde3ba7d402c575c21d 262 SUPERFAMILY SSF81301 5 199 3.27E-56 T 12-10-2018 NPD12_342 66acef9fcfdf7dde3ba7d402c575c21d 262 Gene3D G3DSA:1.10.287.860 149 210 1.1E-23 T 12-10-2018 NPD12_342 66acef9fcfdf7dde3ba7d402c575c21d 262 Gene3D G3DSA:3.30.460.10 2 147 7.7E-50 T 12-10-2018 NPD12_342 66acef9fcfdf7dde3ba7d402c575c21d 262 Pfam PF04607 Region found in RelA / SpoT proteins 45 164 1.0E-34 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 NPD12_1654 9b7c2b45fa96cc41e1983a7459ddd4c6 212 SUPERFAMILY SSF55068 5 143 5.1E-43 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_1654 9b7c2b45fa96cc41e1983a7459ddd4c6 212 Pfam PF01625 Peptide methionine sulfoxide reductase 9 142 9.4E-32 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_1654 9b7c2b45fa96cc41e1983a7459ddd4c6 212 Gene3D G3DSA:3.30.1060.10 3 212 6.7E-59 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 NPD12_2207 84fd8324ddb1a245d2543d861b04811f 379 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 22 371 1.8E-94 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_2207 84fd8324ddb1a245d2543d861b04811f 379 Gene3D G3DSA:3.40.640.10 9 377 1.6E-102 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2207 84fd8324ddb1a245d2543d861b04811f 379 PIRSF PIRSF000390 6 377 4.3E-100 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase NPD12_2207 84fd8324ddb1a245d2543d861b04811f 379 SUPERFAMILY SSF53383 10 375 2.18E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 Gene3D G3DSA:1.10.10.10 12 96 2.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 PIRSF PIRSF019345 4 193 5.0E-54 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 Pfam PF04079 Segregation and condensation complex subunit ScpB 23 181 2.6E-56 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 Hamap MF_01804 Segregation and condensation protein B [scpB]. 11 193 31.087 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 SUPERFAMILY SSF46785 18 94 1.65E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 Gene3D G3DSA:1.10.10.10 97 193 2.9E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 SUPERFAMILY SSF46785 99 172 3.43E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2009 95e73dd36c53cc8f8c17b7aed3eba2f3 193 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 20 188 9.4E-47 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 NPD12_3465 8ef57e35f1821ff72161d2d56698fe36 378 Pfam PF12679 ABC-2 family transporter protein 6 376 2.6E-19 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_1975 77cafbe7932de347a06abf37f58f465c 171 Pfam PF00583 Acetyltransferase (GNAT) family 38 144 5.7E-15 T 12-10-2018 IPR000182 GNAT domain NPD12_1975 77cafbe7932de347a06abf37f58f465c 171 Gene3D G3DSA:3.40.630.30 1 170 1.9E-45 T 12-10-2018 NPD12_1975 77cafbe7932de347a06abf37f58f465c 171 SUPERFAMILY SSF55729 1 156 4.8E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2195 b77cfbb447ce2a83f64a7f3473bcde79 647 Pfam PF00092 von Willebrand factor type A domain 439 602 2.8E-9 T 12-10-2018 IPR002035 von Willebrand factor, type A NPD12_2195 b77cfbb447ce2a83f64a7f3473bcde79 647 Gene3D G3DSA:3.40.50.410 434 621 8.0E-19 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily NPD12_2195 b77cfbb447ce2a83f64a7f3473bcde79 647 SMART SM00327 436 634 1.2E-5 T 12-10-2018 IPR002035 von Willebrand factor, type A NPD12_2195 b77cfbb447ce2a83f64a7f3473bcde79 647 SUPERFAMILY SSF53300 437 602 2.23E-15 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily NPD12_1419 16e931729d70bc55ee1c9e4a0808157c 339 Pfam PF09992 Phosphodiester glycosidase 157 337 5.1E-48 T 12-10-2018 IPR018711 Phosphodiester glycosidase NPD12_337 773198ff25b55e40c1c9b4758e010727 86 Gene3D G3DSA:3.40.1690.10 4 86 1.4E-22 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal NPD12_337 773198ff25b55e40c1c9b4758e010727 86 SUPERFAMILY SSF160544 2 82 1.44E-21 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal NPD12_337 773198ff25b55e40c1c9b4758e010727 86 Pfam PF01312 FlhB HrpN YscU SpaS Family 2 78 6.9E-19 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 NPD12_2759 60909ba5b01626b28cea5616b3d32b83 228 Pfam PF13649 Methyltransferase domain 47 141 2.9E-20 T 12-10-2018 NPD12_2759 60909ba5b01626b28cea5616b3d32b83 228 Gene3D G3DSA:3.40.50.150 22 227 1.8E-39 T 12-10-2018 NPD12_2759 60909ba5b01626b28cea5616b3d32b83 228 SUPERFAMILY SSF53335 18 213 9.6E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_561 0718f630c8ce6067c5e2a901a2c62b68 144 Gene3D G3DSA:3.30.1490.190 85 137 1.2E-6 T 12-10-2018 NPD12_561 0718f630c8ce6067c5e2a901a2c62b68 144 Gene3D G3DSA:1.10.10.10 2 81 4.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_561 0718f630c8ce6067c5e2a901a2c62b68 144 Pfam PF01475 Ferric uptake regulator family 9 126 4.7E-19 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 NPD12_561 0718f630c8ce6067c5e2a901a2c62b68 144 SUPERFAMILY SSF46785 4 132 2.55E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 Gene3D G3DSA:3.40.250.10 311 460 2.7E-42 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 SUPERFAMILY SSF52821 42 162 9.43E-20 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 Pfam PF00581 Rhodanese-like domain 325 446 9.9E-14 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 Pfam PF00581 Rhodanese-like domain 198 291 2.0E-17 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 Pfam PF00581 Rhodanese-like domain 45 155 3.3E-12 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 SMART SM00450 171 295 1.5E-18 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 SMART SM00450 42 159 2.2E-11 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 SMART SM00450 321 450 1.6E-13 T 12-10-2018 IPR001763 Rhodanese-like domain NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 SUPERFAMILY SSF52821 172 349 8.12E-27 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 SUPERFAMILY SSF52821 315 458 4.58E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 Gene3D G3DSA:3.40.250.10 39 158 8.1E-25 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_1333 ed7bb3abb299fd81a7f393284f38983d 460 Gene3D G3DSA:3.40.250.10 164 308 6.5E-40 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily NPD12_2544 5c5968c17fa16f1c5eb1d152e101c21a 541 Gene3D G3DSA:1.25.40.340 6 199 4.8E-13 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_2544 5c5968c17fa16f1c5eb1d152e101c21a 541 SUPERFAMILY SSF101473 2 200 1.7E-47 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_2544 5c5968c17fa16f1c5eb1d152e101c21a 541 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 541 1.1E-213 T 12-10-2018 IPR019986 DAK2 domain-containing protein YloV NPD12_2544 5c5968c17fa16f1c5eb1d152e101c21a 541 SMART SM01120 36 199 1.0E-71 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_2544 5c5968c17fa16f1c5eb1d152e101c21a 541 SMART SM01121 230 541 3.1E-187 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain NPD12_2544 5c5968c17fa16f1c5eb1d152e101c21a 541 Pfam PF13684 Dihydroxyacetone kinase family 230 541 9.5E-129 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain NPD12_2544 5c5968c17fa16f1c5eb1d152e101c21a 541 Pfam PF02734 DAK2 domain 36 198 1.5E-45 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 NPD12_353 8a92a84a3a16e95ac34a5201ebeff8a8 222 Pfam PF04239 Protein of unknown function (DUF421) 86 201 1.8E-37 T 12-10-2018 IPR007353 Protein of unknown function DUF421 NPD12_353 8a92a84a3a16e95ac34a5201ebeff8a8 222 Gene3D G3DSA:3.30.240.20 77 151 5.7E-25 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily NPD12_353 8a92a84a3a16e95ac34a5201ebeff8a8 222 Gene3D G3DSA:3.30.240.20 165 222 1.9E-17 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily NPD12_3403 949f8220ad1d21a4efb24d35d7292900 238 Pfam PF01464 Transglycosylase SLT domain 115 208 6.8E-28 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 NPD12_3403 949f8220ad1d21a4efb24d35d7292900 238 Gene3D G3DSA:1.10.530.10 109 238 9.2E-44 T 12-10-2018 NPD12_3403 949f8220ad1d21a4efb24d35d7292900 238 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 132 160 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 NPD12_3403 949f8220ad1d21a4efb24d35d7292900 238 SUPERFAMILY SSF53955 112 236 9.48E-43 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily NPD12_555 fcd9c608a01f5e4b841a2d55f652a11a 193 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 11 192 7.0E-49 T 12-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 NPD12_555 fcd9c608a01f5e4b841a2d55f652a11a 193 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 19 190 5.2E-31 T 12-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like NPD12_2799 a584dc0247fbade802daf04d78c07d3c 467 SUPERFAMILY SSF101898 176 465 6.28E-30 T 12-10-2018 NPD12_2799 a584dc0247fbade802daf04d78c07d3c 467 Pfam PF13905 Thioredoxin-like 37 129 7.4E-14 T 12-10-2018 IPR012336 Thioredoxin-like fold NPD12_2799 a584dc0247fbade802daf04d78c07d3c 467 Gene3D G3DSA:3.40.30.10 4 153 3.0E-34 T 12-10-2018 NPD12_2799 a584dc0247fbade802daf04d78c07d3c 467 Gene3D G3DSA:2.120.10.30 294 425 1.3E-21 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like NPD12_2799 a584dc0247fbade802daf04d78c07d3c 467 SUPERFAMILY SSF52833 14 148 5.62E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_2799 a584dc0247fbade802daf04d78c07d3c 467 Gene3D G3DSA:2.120.10.30 158 260 3.8E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like NPD12_1370 a3aae6108415ea5af051214b89ecfe8f 266 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 4 257 8.2E-85 T 12-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 NPD12_1370 a3aae6108415ea5af051214b89ecfe8f 266 Pfam PF02540 NAD synthase 12 77 1.1E-5 T 12-10-2018 IPR022310 NAD/GMP synthase NPD12_1370 a3aae6108415ea5af051214b89ecfe8f 266 Gene3D G3DSA:3.40.50.620 2 164 3.8E-28 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1370 a3aae6108415ea5af051214b89ecfe8f 266 SUPERFAMILY SSF52402 17 217 1.01E-36 T 12-10-2018 NPD12_1370 a3aae6108415ea5af051214b89ecfe8f 266 PIRSF PIRSF006661 1 266 1.7E-105 T 12-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 NPD12_1214 bca20f325b20ef2ce04dfbe2d36f1319 162 Gene3D G3DSA:3.40.50.360 3 161 3.8E-14 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_1214 bca20f325b20ef2ce04dfbe2d36f1319 162 Pfam PF12724 Flavodoxin domain 4 141 1.5E-32 T 12-10-2018 IPR026816 Flavodoxin domain NPD12_1214 bca20f325b20ef2ce04dfbe2d36f1319 162 SUPERFAMILY SSF52218 1 151 4.04E-22 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_664 a3ed44d3da79fc05ee9f203576f19980 419 Pfam PF03600 Citrate transporter 11 360 1.2E-56 T 12-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 NPD12_664 a3ed44d3da79fc05ee9f203576f19980 419 PRINTS PR00758 Arsenical pump membrane protein signature 96 120 5.8E-15 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 NPD12_664 a3ed44d3da79fc05ee9f203576f19980 419 PRINTS PR00758 Arsenical pump membrane protein signature 389 413 5.8E-15 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 NPD12_664 a3ed44d3da79fc05ee9f203576f19980 419 PRINTS PR00758 Arsenical pump membrane protein signature 212 237 5.8E-15 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 NPD12_664 a3ed44d3da79fc05ee9f203576f19980 419 PRINTS PR00758 Arsenical pump membrane protein signature 269 293 5.8E-15 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 NPD12_664 a3ed44d3da79fc05ee9f203576f19980 419 PRINTS PR00758 Arsenical pump membrane protein signature 314 336 5.8E-15 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 NPD12_664 a3ed44d3da79fc05ee9f203576f19980 419 PRINTS PR00758 Arsenical pump membrane protein signature 356 381 5.8E-15 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 NPD12_784 daac77dad2477fd5f044799491bf9d11 227 SUPERFAMILY SSF52172 2 126 3.84E-37 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_784 daac77dad2477fd5f044799491bf9d11 227 SUPERFAMILY SSF46894 133 226 2.63E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 NPD12_784 daac77dad2477fd5f044799491bf9d11 227 Gene3D G3DSA:3.40.50.2300 1 122 8.4E-32 T 12-10-2018 NPD12_784 daac77dad2477fd5f044799491bf9d11 227 Pfam PF00072 Response regulator receiver domain 5 113 7.1E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_784 daac77dad2477fd5f044799491bf9d11 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 3.5E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_784 daac77dad2477fd5f044799491bf9d11 227 SMART SM00862 151 226 2.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 NPD12_784 daac77dad2477fd5f044799491bf9d11 227 Gene3D G3DSA:1.10.10.10 126 227 5.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_784 daac77dad2477fd5f044799491bf9d11 227 SMART SM00448 3 113 7.0E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_1540 7940e81ce3a0f123c3e2288b8d92eee6 78 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 7 72 2.4E-22 T 12-10-2018 IPR018680 Protein of unknown function DUF2164 NPD12_1597 1a8330b543926787ab3076f3f005d239 470 Pfam PF12704 MacB-like periplasmic core domain 23 244 9.2E-8 T 12-10-2018 IPR025857 MacB-like periplasmic core domain NPD12_1597 1a8330b543926787ab3076f3f005d239 470 Pfam PF02687 FtsX-like permease family 339 462 2.5E-17 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_2970 a77c3e671ae5afdeac95fa397a1b6dce 170 Gene3D G3DSA:1.10.1760.20 1 166 3.4E-7 T 12-10-2018 NPD12_2970 a77c3e671ae5afdeac95fa397a1b6dce 170 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 159 3.0E-42 T 12-10-2018 NPD12_2970 a77c3e671ae5afdeac95fa397a1b6dce 170 Pfam PF17099 Tryptophan transporter TrpP 2 163 1.3E-57 T 12-10-2018 IPR031360 Tryptophan transporter TrpP NPD12_117 e21a805e89b7243b15edea1c0ff50ef6 282 SMART SM00470 27 116 3.4E-29 T 12-10-2018 IPR003115 ParB/Sulfiredoxin NPD12_117 e21a805e89b7243b15edea1c0ff50ef6 282 SUPERFAMILY SSF109709 108 217 4.97E-32 T 12-10-2018 NPD12_117 e21a805e89b7243b15edea1c0ff50ef6 282 Gene3D G3DSA:1.10.10.2830 103 217 5.4E-35 T 12-10-2018 NPD12_117 e21a805e89b7243b15edea1c0ff50ef6 282 SUPERFAMILY SSF110849 27 151 1.22E-30 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily NPD12_117 e21a805e89b7243b15edea1c0ff50ef6 282 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 26 202 2.0E-58 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 NPD12_117 e21a805e89b7243b15edea1c0ff50ef6 282 Gene3D G3DSA:3.90.1530.30 40 102 5.9E-26 T 12-10-2018 NPD12_117 e21a805e89b7243b15edea1c0ff50ef6 282 Pfam PF02195 ParB-like nuclease domain 29 116 8.1E-25 T 12-10-2018 IPR003115 ParB/Sulfiredoxin NPD12_688 7dd1494efbd97ce9d2cace25343a295c 279 Pfam PF00753 Metallo-beta-lactamase superfamily 24 85 2.9E-9 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_688 7dd1494efbd97ce9d2cace25343a295c 279 SUPERFAMILY SSF56281 11 259 7.34E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_688 7dd1494efbd97ce9d2cace25343a295c 279 Gene3D G3DSA:3.60.15.10 1 279 3.7E-76 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 Pfam PF00162 Phosphoglycerate kinase 8 387 6.0E-167 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 17 27 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PIRSF PIRSF000724 1 398 1.4E-154 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 141 163 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 317 342 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 12 28 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 33 55 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 113 128 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 3.8E-96 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 Gene3D G3DSA:3.40.50.1260 10 395 3.7E-165 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 SUPERFAMILY SSF53748 4 398 1.05E-160 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 Gene3D G3DSA:3.40.50.1260 174 387 3.7E-165 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_385 1e30f9f2d53e77a12ade99139bbed92a 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 7 397 42.989 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 NPD12_576 e6d7ae89f3bb0edd57e103d6f5b0a244 326 PIRSF PIRSF036894 1 310 2.5E-90 T 12-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 NPD12_576 e6d7ae89f3bb0edd57e103d6f5b0a244 326 Pfam PF01238 Phosphomannose isomerase type I 5 103 2.1E-11 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 NPD12_576 e6d7ae89f3bb0edd57e103d6f5b0a244 326 Gene3D G3DSA:2.60.120.10 223 310 2.8E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_576 e6d7ae89f3bb0edd57e103d6f5b0a244 326 Gene3D G3DSA:2.60.120.10 1 219 4.5E-66 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_576 e6d7ae89f3bb0edd57e103d6f5b0a244 326 SUPERFAMILY SSF51182 1 311 2.0E-74 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_1078 1f6bde474781e5ac50ef2da17d8330c4 195 Gene3D G3DSA:3.30.460.10 17 188 8.4E-45 T 12-10-2018 NPD12_1078 1f6bde474781e5ac50ef2da17d8330c4 195 Pfam PF04229 GrpB protein 18 180 4.5E-43 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase NPD12_1078 1f6bde474781e5ac50ef2da17d8330c4 195 SUPERFAMILY SSF81301 21 186 4.9E-45 T 12-10-2018 NPD12_1050 7864870d0922ed5b2b880a48ef5ec2d2 156 Pfam PF12821 Threonine/Serine exporter, ThrE 7 135 1.6E-32 T 12-10-2018 IPR024528 Threonine/Serine exporter, ThrE NPD12_2289 30ab3642eee27b1f7b603cdbb7d18529 145 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 145 1.9E-36 T 12-10-2018 IPR002178 PTS EIIA type-2 domain NPD12_2289 30ab3642eee27b1f7b603cdbb7d18529 145 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 51 67 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain NPD12_2289 30ab3642eee27b1f7b603cdbb7d18529 145 SUPERFAMILY SSF55804 1 145 1.7E-39 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 NPD12_2289 30ab3642eee27b1f7b603cdbb7d18529 145 Gene3D G3DSA:3.40.930.10 1 145 7.4E-54 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 NPD12_3198 f1ad7cddddbc23c366ab7863d7159100 111 Pfam PF01740 STAS domain 7 107 3.1E-24 T 12-10-2018 IPR002645 STAS domain NPD12_3198 f1ad7cddddbc23c366ab7863d7159100 111 SUPERFAMILY SSF52091 3 109 3.73E-30 T 12-10-2018 IPR036513 STAS domain superfamily NPD12_3198 f1ad7cddddbc23c366ab7863d7159100 111 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 4 108 1.0E-42 T 12-10-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 NPD12_3198 f1ad7cddddbc23c366ab7863d7159100 111 Gene3D G3DSA:3.30.750.24 6 111 4.1E-31 T 12-10-2018 IPR036513 STAS domain superfamily NPD12_3198 f1ad7cddddbc23c366ab7863d7159100 111 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 106 5.8E-31 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 NPD12_3390 62633516e1b4d1a1394ae8a5dcfbc8d1 199 Pfam PF01725 Ham1 family 5 192 3.9E-58 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 NPD12_3390 62633516e1b4d1a1394ae8a5dcfbc8d1 199 SUPERFAMILY SSF52972 2 195 8.9E-67 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like NPD12_3390 62633516e1b4d1a1394ae8a5dcfbc8d1 199 Hamap MF_01405 dITP/XTP pyrophosphatase. 3 197 46.932 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 NPD12_3390 62633516e1b4d1a1394ae8a5dcfbc8d1 199 Gene3D G3DSA:3.90.950.10 1 198 1.7E-72 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like NPD12_3390 62633516e1b4d1a1394ae8a5dcfbc8d1 199 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 194 4.8E-59 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 NPD12_2210 c9df67e20037b69a3b73fb216a91b721 326 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 313 8.1E-84 T 12-10-2018 IPR016040 NAD(P)-binding domain NPD12_2210 c9df67e20037b69a3b73fb216a91b721 326 SUPERFAMILY SSF51735 1 325 1.65E-90 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2210 c9df67e20037b69a3b73fb216a91b721 326 Gene3D G3DSA:3.40.50.720 4 312 6.7E-126 T 12-10-2018 NPD12_2210 c9df67e20037b69a3b73fb216a91b721 326 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 325 3.2E-140 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 NPD12_2210 c9df67e20037b69a3b73fb216a91b721 326 Gene3D G3DSA:3.90.25.10 199 321 6.7E-126 T 12-10-2018 NPD12_3537 bb2f36d248080cf102fb9ed6b7390f77 298 SUPERFAMILY SSF109604 147 287 5.58E-14 T 12-10-2018 NPD12_3537 bb2f36d248080cf102fb9ed6b7390f77 298 Gene3D G3DSA:2.40.50.140 1 99 7.0E-7 T 12-10-2018 NPD12_3537 bb2f36d248080cf102fb9ed6b7390f77 298 Pfam PF01336 OB-fold nucleic acid binding domain 16 89 1.4E-6 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 NPD12_3537 bb2f36d248080cf102fb9ed6b7390f77 298 Gene3D G3DSA:1.10.3210.10 138 297 2.9E-11 T 12-10-2018 NPD12_3537 bb2f36d248080cf102fb9ed6b7390f77 298 SUPERFAMILY SSF50249 2 103 1.32E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_3537 bb2f36d248080cf102fb9ed6b7390f77 298 Pfam PF01966 HD domain 165 287 2.5E-7 T 12-10-2018 IPR006674 HD domain NPD12_2676 d42642697cdb47267e92122eb8b72537 199 Gene3D G3DSA:1.20.5.620 20 98 1.3E-19 T 12-10-2018 NPD12_2676 d42642697cdb47267e92122eb8b72537 199 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 199 13.89 T 12-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2676 d42642697cdb47267e92122eb8b72537 199 SUPERFAMILY SSF160527 81 198 4.97E-20 T 12-10-2018 NPD12_2676 d42642697cdb47267e92122eb8b72537 199 Pfam PF01991 ATP synthase (E/31 kDa) subunit 11 198 7.9E-20 T 12-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2676 d42642697cdb47267e92122eb8b72537 199 SUPERFAMILY SSF81573 10 65 4.32E-5 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily NPD12_2958 3e911e29f2aad1c7ade118e16c0f35d2 200 SUPERFAMILY SSF54001 41 197 1.77E-37 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_2958 3e911e29f2aad1c7ade118e16c0f35d2 200 Pfam PF05257 CHAP domain 72 166 7.8E-17 T 12-10-2018 IPR007921 CHAP domain NPD12_2958 3e911e29f2aad1c7ade118e16c0f35d2 200 Gene3D G3DSA:3.90.1720.10 26 200 3.9E-40 T 12-10-2018 NPD12_2741 0530d728668c56a692f2ad71ceb4d9c2 55 SUPERFAMILY SSF140500 4 52 1.15E-7 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 NPD12_2741 0530d728668c56a692f2ad71ceb4d9c2 55 Pfam PF09388 Spo0E like sporulation regulatory protein 7 51 1.3E-9 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 Pfam PF00398 Ribosomal RNA adenine dimethylase 12 270 2.6E-68 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 SUPERFAMILY SSF53335 9 273 1.59E-76 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 SMART SM00650 28 200 2.0E-78 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 12 269 5.9E-86 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 44 71 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 12 272 54.598 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 Gene3D G3DSA:1.10.8.100 208 273 9.0E-24 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 NPD12_237 4ac16eb8e379aa286ac91b24d561d0c3 275 Gene3D G3DSA:3.40.50.150 1 204 2.0E-73 T 12-10-2018 NPD12_1415 34a55207c2be4c3ca536a4abeca786e3 532 PIRSF PIRSF002741 1 528 4.9E-113 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 NPD12_1415 34a55207c2be4c3ca536a4abeca786e3 532 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 93 115 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site NPD12_1415 34a55207c2be4c3ca536a4abeca786e3 532 SUPERFAMILY SSF53850 42 524 7.6E-121 T 12-10-2018 NPD12_1415 34a55207c2be4c3ca536a4abeca786e3 532 Gene3D G3DSA:3.10.105.10 287 496 8.3E-144 T 12-10-2018 NPD12_1415 34a55207c2be4c3ca536a4abeca786e3 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 448 8.1E-85 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain NPD12_1415 34a55207c2be4c3ca536a4abeca786e3 532 Gene3D G3DSA:3.40.190.10 52 503 8.3E-144 T 12-10-2018 NPD12_1415 34a55207c2be4c3ca536a4abeca786e3 532 Gene3D G3DSA:3.90.76.10 77 195 8.3E-144 T 12-10-2018 NPD12_992 bb4336d28c7cbf78b84a5dbc12b91d24 178 Pfam PF08281 Sigma-70, region 4 120 166 2.4E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_992 bb4336d28c7cbf78b84a5dbc12b91d24 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 168 2.8E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_992 bb4336d28c7cbf78b84a5dbc12b91d24 178 TIGRFAM TIGR03209 P21_Cbot: transcriptional regulator BotR, P-21 18 159 8.6E-73 T 12-10-2018 IPR017622 Transcription regulator, P21/BotR , Clostridium toxin-associated NPD12_992 bb4336d28c7cbf78b84a5dbc12b91d24 178 SUPERFAMILY SSF88659 118 175 9.53E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_992 bb4336d28c7cbf78b84a5dbc12b91d24 178 Gene3D G3DSA:1.10.10.10 110 178 3.6E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2173 cdaf3576ac78c8d6723aed69eaf185e2 302 SUPERFAMILY SSF103481 214 299 7.98E-13 T 12-10-2018 NPD12_2173 cdaf3576ac78c8d6723aed69eaf185e2 302 Pfam PF00892 EamA-like transporter family 154 296 5.0E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_2173 cdaf3576ac78c8d6723aed69eaf185e2 302 Pfam PF00892 EamA-like transporter family 8 141 1.3E-25 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_2173 cdaf3576ac78c8d6723aed69eaf185e2 302 SUPERFAMILY SSF103481 44 143 1.96E-12 T 12-10-2018 NPD12_3540 c217806ef5b7a32db5c62cc116436093 145 Gene3D G3DSA:2.60.200.20 31 145 1.4E-25 T 12-10-2018 NPD12_3540 c217806ef5b7a32db5c62cc116436093 145 SMART SM00240 72 122 4.1E-11 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 NPD12_3540 c217806ef5b7a32db5c62cc116436093 145 Pfam PF00498 FHA domain 73 137 7.5E-17 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 NPD12_3540 c217806ef5b7a32db5c62cc116436093 145 SUPERFAMILY SSF49879 66 144 7.27E-24 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 NPD12_2209 1689e92c7ac5f64e9041fafa93d19d2c 353 Gene3D G3DSA:3.90.550.10 1 238 5.9E-73 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2209 1689e92c7ac5f64e9041fafa93d19d2c 353 Gene3D G3DSA:2.160.10.10 239 350 8.1E-11 T 12-10-2018 NPD12_2209 1689e92c7ac5f64e9041fafa93d19d2c 353 SUPERFAMILY SSF53448 1 303 8.34E-76 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2209 1689e92c7ac5f64e9041fafa93d19d2c 353 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 353 5.6E-132 T 12-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form NPD12_2209 1689e92c7ac5f64e9041fafa93d19d2c 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 247 270 4.0E-4 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_2209 1689e92c7ac5f64e9041fafa93d19d2c 353 Pfam PF00483 Nucleotidyl transferase 2 234 9.8E-55 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 NPD12_974 f6b90f25c931436de436a9f1dbe65a3d 315 Pfam PF01497 Periplasmic binding protein 55 285 5.3E-30 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_974 f6b90f25c931436de436a9f1dbe65a3d 315 Gene3D G3DSA:3.40.50.1980 30 139 1.2E-31 T 12-10-2018 NPD12_974 f6b90f25c931436de436a9f1dbe65a3d 315 Gene3D G3DSA:3.40.50.1980 141 314 3.6E-59 T 12-10-2018 NPD12_974 f6b90f25c931436de436a9f1dbe65a3d 315 SUPERFAMILY SSF53807 37 306 3.93E-65 T 12-10-2018 NPD12_1115 6bb9713fcd63fc7960fe6c6961b413e9 141 SUPERFAMILY SSF55729 1 140 8.67E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1115 6bb9713fcd63fc7960fe6c6961b413e9 141 Gene3D G3DSA:3.40.630.30 39 141 3.4E-27 T 12-10-2018 NPD12_1115 6bb9713fcd63fc7960fe6c6961b413e9 141 Pfam PF00583 Acetyltransferase (GNAT) family 45 119 8.9E-12 T 12-10-2018 IPR000182 GNAT domain NPD12_53 52b20d7899b9bf42b525cfaa66820099 457 Pfam PF00474 Sodium:solute symporter family 31 415 8.4E-23 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 NPD12_53 52b20d7899b9bf42b525cfaa66820099 457 Gene3D G3DSA:1.20.1730.10 18 456 3.0E-48 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily NPD12_417 87ffb6afbb39a1fa94507d1422e3fbf8 174 Pfam PF01872 RibD C-terminal domain 3 152 1.9E-17 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 NPD12_417 87ffb6afbb39a1fa94507d1422e3fbf8 174 Gene3D G3DSA:3.40.430.10 1 174 9.1E-40 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 NPD12_417 87ffb6afbb39a1fa94507d1422e3fbf8 174 SUPERFAMILY SSF53597 3 172 9.29E-31 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 NPD12_1901 6800aa7a36f75359d6218cdfabf7a29c 446 Pfam PF00860 Permease family 34 403 1.0E-27 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 NPD12_2647 0b08a6147c47d464c84695516a845313 1621 SUPERFAMILY SSF52374 919 1113 1.06E-19 T 12-10-2018 NPD12_2647 0b08a6147c47d464c84695516a845313 1621 SUPERFAMILY SSF48371 389 854 1.01E-14 T 12-10-2018 IPR016024 Armadillo-type fold NPD12_2647 0b08a6147c47d464c84695516a845313 1621 Gene3D G3DSA:3.40.50.620 917 1115 5.6E-24 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2647 0b08a6147c47d464c84695516a845313 1621 SUPERFAMILY SSF109604 163 314 7.18E-10 T 12-10-2018 NPD12_2647 0b08a6147c47d464c84695516a845313 1621 Pfam PF01467 Cytidylyltransferase-like 922 1082 3.1E-6 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 NPD12_1556 549cc6479c93e76534a813a450a2cdce 264 Pfam PF02517 CAAX protease self-immunity 133 220 1.5E-19 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_3517 6302dc56bc6c2113b05e4cd9bdaff3bf 134 SUPERFAMILY SSF53927 2 132 8.03E-27 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 NPD12_3517 6302dc56bc6c2113b05e4cd9bdaff3bf 134 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 26 99 1.3E-7 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain NPD12_3517 6302dc56bc6c2113b05e4cd9bdaff3bf 134 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 95 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 NPD12_3517 6302dc56bc6c2113b05e4cd9bdaff3bf 134 Gene3D G3DSA:3.40.140.10 3 132 7.0E-32 T 12-10-2018 NPD12_266 c1ceb09d6d7d78975273c1ff6841fc5b 255 Gene3D G3DSA:3.90.1200.10 28 252 1.6E-24 T 12-10-2018 NPD12_1625 b373d30bfc0516ec7fef03c02af5a7ad 270 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1625 b373d30bfc0516ec7fef03c02af5a7ad 270 SUPERFAMILY SSF52540 1 237 4.53E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1625 b373d30bfc0516ec7fef03c02af5a7ad 270 Pfam PF00005 ABC transporter 29 179 1.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1625 b373d30bfc0516ec7fef03c02af5a7ad 270 Gene3D G3DSA:3.40.50.300 1 269 2.1E-73 T 12-10-2018 NPD12_1625 b373d30bfc0516ec7fef03c02af5a7ad 270 SMART SM00382 37 230 4.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3195 016eb422d877eea905ac1bcf012680d9 151 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 29 144 3.8E-41 T 12-10-2018 IPR005562 SpoVA NPD12_3195 016eb422d877eea905ac1bcf012680d9 151 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 11 148 2.3E-60 T 12-10-2018 IPR014203 Sporulation stage V, protein AC NPD12_1086 950ec719f6e9a845032561e76beb320d 786 Pfam PF00005 ABC transporter 21 169 2.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1086 950ec719f6e9a845032561e76beb320d 786 Gene3D G3DSA:3.40.50.300 1 251 5.8E-72 T 12-10-2018 NPD12_1086 950ec719f6e9a845032561e76beb320d 786 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1086 950ec719f6e9a845032561e76beb320d 786 SUPERFAMILY SSF52540 1 225 1.14E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1086 950ec719f6e9a845032561e76beb320d 786 SMART SM00382 30 217 6.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1086 950ec719f6e9a845032561e76beb320d 786 Pfam PF02687 FtsX-like permease family 686 779 3.1E-14 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_3257 57b6acb904f8e242f91c7716ac731046 246 SUPERFAMILY SSF53335 2 246 8.36E-50 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_3257 57b6acb904f8e242f91c7716ac731046 246 Pfam PF13649 Methyltransferase domain 43 137 5.0E-16 T 12-10-2018 NPD12_3257 57b6acb904f8e242f91c7716ac731046 246 Gene3D G3DSA:2.20.25.110 145 205 1.7E-75 T 12-10-2018 NPD12_3257 57b6acb904f8e242f91c7716ac731046 246 Gene3D G3DSA:3.40.50.150 4 226 1.7E-75 T 12-10-2018 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 SMART SM00283 410 685 1.9E-52 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 SMART SM00304 626 682 110.0 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 SMART SM00304 326 381 1.3E-5 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 SUPERFAMILY SSF58104 356 684 3.79E-60 T 12-10-2018 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 Gene3D G3DSA:1.10.287.950 326 628 5.7E-59 T 12-10-2018 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 Gene3D G3DSA:3.30.450.20 94 198 9.2E-36 T 12-10-2018 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 SUPERFAMILY SSF103190 145 207 2.55E-9 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 Pfam PF02743 Cache domain 48 289 1.1E-35 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 478 637 2.4E-34 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2841 db20ad8ab21167a5d2183dc224773b40 686 Gene3D G3DSA:3.30.450.20 199 299 9.2E-36 T 12-10-2018 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 Gene3D G3DSA:3.30.1750.20 20 189 5.7E-80 T 12-10-2018 IPR038585 Clostridium enterotoxin, N-terminal domain superfamily NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 Pfam PF03505 Clostridium enterotoxin 46 157 2.8E-11 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 Pfam PF03505 Clostridium enterotoxin 230 426 4.7E-107 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 Gene3D G3DSA:2.60.120.1090 517 626 2.8E-64 T 12-10-2018 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 Gene3D G3DSA:3.30.1750.20 206 346 1.0E-68 T 12-10-2018 IPR038585 Clostridium enterotoxin, N-terminal domain superfamily NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 Gene3D G3DSA:2.60.120.1080 365 516 3.0E-88 T 12-10-2018 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 PRINTS PR01394 Clostridium enterotoxin signature 396 410 1.6E-33 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 PRINTS PR01394 Clostridium enterotoxin signature 414 426 1.6E-33 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 PRINTS PR01394 Clostridium enterotoxin signature 358 376 1.6E-33 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 PRINTS PR01394 Clostridium enterotoxin signature 299 318 1.6E-33 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 PRINTS PR01394 Clostridium enterotoxin signature 526 537 1.6E-33 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 PRINTS PR01394 Clostridium enterotoxin signature 230 249 1.6E-33 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_989 883b4377dd28747a6c6ecd1c1987bb04 626 PRINTS PR01394 Clostridium enterotoxin signature 322 336 1.6E-33 T 12-10-2018 IPR003897 Clostridium enterotoxin GO:0005576|GO:0009405 NPD12_938 92dbdaaf3cf548aade51dac5611fbddb 123 Gene3D G3DSA:3.40.30.10 1 110 2.0E-42 T 12-10-2018 NPD12_938 92dbdaaf3cf548aade51dac5611fbddb 123 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 1 123 1.8E-47 T 12-10-2018 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 NPD12_667 67a85a05090227928254a5dc8c72e8a8 87 Pfam PF13031 Protein of unknown function (DUF3892) 12 79 1.4E-11 T 12-10-2018 IPR024997 Protein of unknown function DUF3892 NPD12_2978 486113f79cbc8a7cca72e4ebeb988356 320 SUPERFAMILY SSF48452 39 176 5.57E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_2978 486113f79cbc8a7cca72e4ebeb988356 320 Gene3D G3DSA:1.25.40.10 9 226 1.1E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 238 429 1.7E-35 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 Gene3D G3DSA:3.40.50.880 234 439 3.1E-9 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 SUPERFAMILY SSF52540 1 190 1.04E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 Gene3D G3DSA:3.40.50.300 2 187 7.3E-20 T 12-10-2018 NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 SUPERFAMILY SSF52317 236 439 1.94E-26 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 185 3.1E-16 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 1 431 38.801 T 12-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 NPD12_1109 878022f878d7fbe47451cf1b831669bc 440 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 4 438 3.9E-125 T 12-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 NPD12_2199 9f61d978ad787a498eb020b0b031ed76 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 56 3.4E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_2199 9f61d978ad787a498eb020b0b031ed76 189 SUPERFAMILY SSF46689 4 68 5.82E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2199 9f61d978ad787a498eb020b0b031ed76 189 Gene3D G3DSA:1.10.357.10 2 181 9.6E-39 T 12-10-2018 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 608 40.477 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 Gene3D G3DSA:3.40.50.10490 446 593 3.4E-146 T 12-10-2018 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 608 1.1E-248 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 Gene3D G3DSA:3.60.20.10 2 239 8.7E-79 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 SUPERFAMILY SSF56235 2 234 1.03E-73 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 Gene3D G3DSA:3.40.50.10490 246 607 3.4E-146 T 12-10-2018 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 Pfam PF01380 SIS domain 461 590 4.2E-24 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 Pfam PF01380 SIS domain 291 415 2.1E-31 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 Pfam PF13522 Glutamine amidotransferase domain 64 191 8.6E-22 T 12-10-2018 NPD12_3568 892bf1cbda83d7b3664c11ef42569ddc 608 SUPERFAMILY SSF53697 245 608 8.91E-108 T 12-10-2018 NPD12_3442 c6295f485128e1d35a9efc950e9604e1 209 Gene3D G3DSA:3.30.1330.70 15 128 2.0E-7 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 NPD12_3442 c6295f485128e1d35a9efc950e9604e1 209 SUPERFAMILY SSF103084 12 126 3.14E-20 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 NPD12_3442 c6295f485128e1d35a9efc950e9604e1 209 Pfam PF05866 Endodeoxyribonuclease RusA 11 124 3.6E-18 T 12-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 NPD12_2310 6fe522003c2945bc017d0f4a44a55d36 244 Gene3D G3DSA:1.10.510.10 98 237 2.7E-16 T 12-10-2018 NPD12_2310 6fe522003c2945bc017d0f4a44a55d36 244 Gene3D G3DSA:3.30.200.20 4 96 2.5E-12 T 12-10-2018 NPD12_2310 6fe522003c2945bc017d0f4a44a55d36 244 SUPERFAMILY SSF56112 17 209 4.51E-34 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_2310 6fe522003c2945bc017d0f4a44a55d36 244 Pfam PF00069 Protein kinase domain 21 173 5.5E-27 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 NPD12_2310 6fe522003c2945bc017d0f4a44a55d36 244 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 27 48 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 NPD12_2310 6fe522003c2945bc017d0f4a44a55d36 244 SMART SM00220 21 236 5.6E-10 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 NPD12_242 8132bdb3336d6c03c2b170b848a7cf0d 231 Gene3D G3DSA:3.40.50.300 1 229 1.0E-66 T 12-10-2018 NPD12_242 8132bdb3336d6c03c2b170b848a7cf0d 231 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_242 8132bdb3336d6c03c2b170b848a7cf0d 231 SUPERFAMILY SSF52540 1 223 2.16E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_242 8132bdb3336d6c03c2b170b848a7cf0d 231 SMART SM00382 30 217 5.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_242 8132bdb3336d6c03c2b170b848a7cf0d 231 Pfam PF00005 ABC transporter 21 169 1.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1252 66d5f6d704e975f76852399ae3123e13 331 Pfam PF06081 Aromatic acid exporter family member 1 3 142 1.4E-49 T 12-10-2018 IPR010343 Aromatic acid exporter family member 1 NPD12_1252 66d5f6d704e975f76852399ae3123e13 331 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 311 4.7E-54 T 12-10-2018 IPR021062 Putative aromatic acid exporter, C-terminal NPD12_1252 66d5f6d704e975f76852399ae3123e13 331 Gene3D G3DSA:1.20.120.940 141 316 1.1E-54 T 12-10-2018 IPR038323 Putative aromatic acid exporter, C-terminal domain superfamily NPD12_2081 830697992e1fbe79b52cf42ac7e28ae9 125 Pfam PF01230 HIT domain 10 103 3.7E-22 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_2081 830697992e1fbe79b52cf42ac7e28ae9 125 PRINTS PR00332 Histidine triad family signature 22 40 7.9E-6 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_2081 830697992e1fbe79b52cf42ac7e28ae9 125 PRINTS PR00332 Histidine triad family signature 89 99 7.9E-6 T 12-10-2018 IPR001310 Histidine triad (HIT) protein NPD12_2081 830697992e1fbe79b52cf42ac7e28ae9 125 ProSitePatterns PS00892 HIT domain signature. 82 100 - T 12-10-2018 IPR019808 Histidine triad, conserved site NPD12_2081 830697992e1fbe79b52cf42ac7e28ae9 125 SUPERFAMILY SSF54197 2 116 2.94E-37 T 12-10-2018 IPR036265 HIT-like superfamily NPD12_2081 830697992e1fbe79b52cf42ac7e28ae9 125 Gene3D G3DSA:3.30.428.10 1 116 4.6E-39 T 12-10-2018 IPR036265 HIT-like superfamily NPD12_356 14baa2377fc3c9fc5dcef034aefa678f 173 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 14 169 3.4E-37 T 12-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 NPD12_356 14baa2377fc3c9fc5dcef034aefa678f 173 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 50 72 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 NPD12_356 14baa2377fc3c9fc5dcef034aefa678f 173 Pfam PF01066 CDP-alcohol phosphatidyltransferase 9 72 1.7E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 NPD12_356 14baa2377fc3c9fc5dcef034aefa678f 173 Gene3D G3DSA:1.20.120.1760 1 171 1.2E-13 T 12-10-2018 NPD12_630 1407d5a94360055be54bb0497246a2b5 189 SUPERFAMILY SSF140478 29 176 2.22E-55 T 12-10-2018 IPR023353 LemA-like domain superfamily NPD12_630 1407d5a94360055be54bb0497246a2b5 189 Pfam PF04011 LemA family 10 187 5.6E-73 T 12-10-2018 IPR007156 LemA NPD12_630 1407d5a94360055be54bb0497246a2b5 189 Gene3D G3DSA:1.20.1440.20 21 187 3.4E-71 T 12-10-2018 IPR023353 LemA-like domain superfamily NPD12_3649 a1fe669266555879e0f1a366143ebf5d 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 27.293 T 12-10-2018 IPR022973 Ribosomal protein L10 NPD12_3649 a1fe669266555879e0f1a366143ebf5d 166 SUPERFAMILY SSF160369 4 160 7.98E-54 T 12-10-2018 NPD12_3649 a1fe669266555879e0f1a366143ebf5d 166 Pfam PF00466 Ribosomal protein L10 3 101 4.1E-27 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 NPD12_3649 a1fe669266555879e0f1a366143ebf5d 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 19 141 9.0E-8 T 12-10-2018 NPD12_3649 a1fe669266555879e0f1a366143ebf5d 166 Gene3D G3DSA:3.30.70.1730 3 133 1.7E-41 T 12-10-2018 NPD12_468 efebf0440b20ca03890a9066a2708d66 372 Gene3D G3DSA:1.10.3470.10 23 369 7.1E-103 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_468 efebf0440b20ca03890a9066a2708d66 372 SUPERFAMILY SSF81345 22 364 1.27E-80 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_468 efebf0440b20ca03890a9066a2708d66 372 Pfam PF01032 FecCD transport family 38 364 6.2E-94 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_1476 85ced37820d67e8b014c3676c7aaf02d 89 Pfam PF07659 Domain of Unknown Function (DUF1599) 22 85 3.0E-19 T 12-10-2018 IPR011630 Clostridium phage phiCTP1, Gp74 NPD12_1 fa23aba70339b084a62bb62d837c406c 132 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 4 120 3.4E-38 T 12-10-2018 IPR014242 Spore cortex biosynthesis protein, YabQ NPD12_1 fa23aba70339b084a62bb62d837c406c 132 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 13 90 1.3E-15 T 12-10-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 SUPERFAMILY SSF46785 7 134 6.94E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 98 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 Gene3D G3DSA:1.10.10.10 5 139 4.5E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 SMART SM00347 25 125 1.9E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 5.1E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 5.1E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 5.1E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 5.1E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1296 9d16f8b5cd0ab1e8be281a95fd2de390 145 Pfam PF01047 MarR family 38 89 8.6E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 SUPERFAMILY SSF48557 8 454 1.57E-99 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 SMART SM00998 369 453 3.2E-28 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 Gene3D G3DSA:1.20.200.10 12 449 7.1E-159 T 12-10-2018 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 4.4E-9 T 12-10-2018 IPR000362 Fumarate lyase family NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 4.4E-9 T 12-10-2018 IPR000362 Fumarate lyase family NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 4.4E-9 T 12-10-2018 IPR000362 Fumarate lyase family NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 9 451 2.3E-118 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 449 2.2E-18 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 Gene3D G3DSA:1.10.40.30 367 441 7.1E-159 T 12-10-2018 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 Gene3D G3DSA:1.10.275.60 23 234 7.1E-159 T 12-10-2018 NPD12_2443 6e1ce1a26b45e299fc0e0471ca449deb 476 Pfam PF00206 Lyase 26 303 3.5E-22 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal NPD12_3035 1d4fc99d8802ae120ba18fd4f155890a 114 Pfam PF10844 Protein of unknown function (DUF2577) 7 112 1.3E-28 T 12-10-2018 IPR022555 Protein of unknown function, DUF2577 NPD12_3035 1d4fc99d8802ae120ba18fd4f155890a 114 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 5 113 2.0E-6 T 12-10-2018 IPR022555 Protein of unknown function, DUF2577 NPD12_765 f96c9cc4528034b37cfeacb02ffddfaa 822 Pfam PF02687 FtsX-like permease family 722 813 1.0E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_765 f96c9cc4528034b37cfeacb02ffddfaa 822 Pfam PF02687 FtsX-like permease family 282 369 3.8E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_2426 7f865595e90db7fede692dcd5ea37813 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 362 1.6E-90 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_2426 7f865595e90db7fede692dcd5ea37813 368 Gene3D G3DSA:1.20.1740.10 3 366 7.2E-6 T 12-10-2018 NPD12_2426 7f865595e90db7fede692dcd5ea37813 368 Pfam PF03845 Spore germination protein 9 319 1.4E-54 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 Gene3D G3DSA:3.40.50.300 140 321 2.9E-66 T 12-10-2018 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 SUPERFAMILY SSF140990 403 575 2.62E-51 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 Gene3D G3DSA:1.20.58.760 396 576 1.4E-56 T 12-10-2018 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 187 319 3.2E-42 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 ProSitePatterns PS00674 AAA-protein family signature. 290 308 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 Gene3D G3DSA:1.10.8.60 322 395 1.1E-18 T 12-10-2018 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 Pfam PF01434 Peptidase family M41 382 576 9.2E-54 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 SMART SM00382 183 322 3.5E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 576 30.171 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 576 3.8E-166 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 NPD12_565 a904dd6f95134fea0c869d9348e3c21a 576 SUPERFAMILY SSF52540 145 388 1.18E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2052 f28f0c70cdcf98d5f47cf3fb397720dd 143 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 143 21.502 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 NPD12_2052 f28f0c70cdcf98d5f47cf3fb397720dd 143 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 142 3.7E-44 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 NPD12_2052 f28f0c70cdcf98d5f47cf3fb397720dd 143 Gene3D G3DSA:1.10.940.10 1 143 1.2E-43 T 12-10-2018 IPR035926 NusB-like superfamily NPD12_2052 f28f0c70cdcf98d5f47cf3fb397720dd 143 Pfam PF01029 NusB family 4 142 3.1E-42 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 NPD12_2052 f28f0c70cdcf98d5f47cf3fb397720dd 143 SUPERFAMILY SSF48013 2 142 1.2E-37 T 12-10-2018 IPR035926 NusB-like superfamily NPD12_257 9f48c2699eb76cd5a62b7a04e4a24276 355 Pfam PF00483 Nucleotidyl transferase 4 279 7.0E-47 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 NPD12_257 9f48c2699eb76cd5a62b7a04e4a24276 355 SUPERFAMILY SSF53448 2 278 4.9E-61 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_257 9f48c2699eb76cd5a62b7a04e4a24276 355 Gene3D G3DSA:3.90.550.10 2 348 1.3E-110 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_257 9f48c2699eb76cd5a62b7a04e4a24276 355 SUPERFAMILY SSF159283 285 346 4.58E-14 T 12-10-2018 NPD12_1096 95490d1e1cd846dc0f2bb181aff7f494 293 SUPERFAMILY SSF48452 39 187 4.13E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1096 95490d1e1cd846dc0f2bb181aff7f494 293 Gene3D G3DSA:1.25.40.10 27 240 1.1E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_635 49e331636c01630be9fab45927087098 196 Gene3D G3DSA:3.40.50.150 4 192 1.5E-31 T 12-10-2018 NPD12_635 49e331636c01630be9fab45927087098 196 SUPERFAMILY SSF53335 5 182 6.57E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_635 49e331636c01630be9fab45927087098 196 Pfam PF13847 Methyltransferase domain 35 152 1.3E-17 T 12-10-2018 IPR025714 Methyltransferase domain NPD12_3347 f56dc77e98074718c03655c8a105faf1 298 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 297 3.1E-106 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 NPD12_3347 f56dc77e98074718c03655c8a105faf1 298 Pfam PF01180 Dihydroorotate dehydrogenase 1 283 4.9E-72 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 NPD12_3347 f56dc77e98074718c03655c8a105faf1 298 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 236 256 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 NPD12_3347 f56dc77e98074718c03655c8a105faf1 298 Gene3D G3DSA:3.20.20.70 1 297 3.5E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_3347 f56dc77e98074718c03655c8a105faf1 298 SUPERFAMILY SSF51395 2 297 4.03E-83 T 12-10-2018 NPD12_3347 f56dc77e98074718c03655c8a105faf1 298 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 2 298 39.686 T 12-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 NPD12_3347 f56dc77e98074718c03655c8a105faf1 298 PIRSF PIRSF000164 1 298 1.6E-77 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 NPD12_710 026c1358d9edc02f37edfdbea262a0db 196 Gene3D G3DSA:2.30.30.110 69 196 7.1E-36 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor NPD12_710 026c1358d9edc02f37edfdbea262a0db 196 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 83 194 1.3E-29 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 NPD12_710 026c1358d9edc02f37edfdbea262a0db 196 SUPERFAMILY SSF50118 80 195 1.44E-27 T 12-10-2018 NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 Pfam PF04542 Sigma-70 region 2 22 88 7.0E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 168 4.6E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 TIGRFAM TIGR02954 Sig70_famx3: RNA polymerase sigma-70 factor, TIGR02954 family 1 170 9.9E-72 T 12-10-2018 IPR014300 RNA polymerase sigma-V type NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 Pfam PF08281 Sigma-70, region 4 113 165 5.4E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 SUPERFAMILY SSF88659 103 169 6.92E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 Gene3D G3DSA:1.10.1740.10 1 112 3.2E-21 T 12-10-2018 NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 Gene3D G3DSA:1.10.10.10 113 170 5.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1022 1ba9d42f8b5e3d6eb28907995b132866 171 SUPERFAMILY SSF88946 1 97 4.19E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_1939 34b0be152b38b671f4ceb67c851414f5 452 Pfam PF07670 Nucleoside recognition 139 234 4.5E-7 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_3085 68beadbb9069d0241116391178f4ca56 415 Gene3D G3DSA:3.40.710.10 19 301 3.5E-92 T 12-10-2018 NPD12_3085 68beadbb9069d0241116391178f4ca56 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 137 150 3.2E-12 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_3085 68beadbb9069d0241116391178f4ca56 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 62 73 3.2E-12 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_3085 68beadbb9069d0241116391178f4ca56 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 110 127 3.2E-12 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_3085 68beadbb9069d0241116391178f4ca56 415 SUPERFAMILY SSF56601 5 280 2.82E-70 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_3085 68beadbb9069d0241116391178f4ca56 415 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 258 2.0E-56 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 NPD12_3085 68beadbb9069d0241116391178f4ca56 415 SMART SM00936 280 367 1.1E-4 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 NPD12_3085 68beadbb9069d0241116391178f4ca56 415 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 283 366 1.3E-5 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 NPD12_3186 9d72b8e260cbecade44fdfe03d86e2b2 297 Pfam PF01909 Nucleotidyltransferase domain 15 95 2.1E-10 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 NPD12_3186 9d72b8e260cbecade44fdfe03d86e2b2 297 Gene3D G3DSA:3.30.460.10 3 88 1.3E-9 T 12-10-2018 NPD12_3186 9d72b8e260cbecade44fdfe03d86e2b2 297 SUPERFAMILY SSF81301 5 81 1.1E-12 T 12-10-2018 NPD12_1584 5f7692a631b1f1e2c8f5631ca16cf023 124 Gene3D G3DSA:1.10.10.10 9 124 8.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1584 5f7692a631b1f1e2c8f5631ca16cf023 124 SMART SM00345 13 76 7.5E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_1584 5f7692a631b1f1e2c8f5631ca16cf023 124 SUPERFAMILY SSF46785 6 78 1.07E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1584 5f7692a631b1f1e2c8f5631ca16cf023 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 9.3E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 NPD12_3152 5328d164fdff1cccc5a0ee67802a7ebe 136 Gene3D G3DSA:1.10.260.40 2 83 5.8E-23 T 12-10-2018 NPD12_3152 5328d164fdff1cccc5a0ee67802a7ebe 136 Pfam PF01381 Helix-turn-helix 12 62 1.1E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3152 5328d164fdff1cccc5a0ee67802a7ebe 136 SMART SM00530 7 62 1.4E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3152 5328d164fdff1cccc5a0ee67802a7ebe 136 SUPERFAMILY SSF47413 3 70 3.38E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_1952 55fb5a8b19c5b3fd9bebd1c080c5a15b 396 SUPERFAMILY SSF53383 2 395 1.14E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_1952 55fb5a8b19c5b3fd9bebd1c080c5a15b 396 Gene3D G3DSA:3.40.640.10 64 286 2.7E-141 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_1952 55fb5a8b19c5b3fd9bebd1c080c5a15b 396 Gene3D G3DSA:3.90.1150.10 17 391 2.7E-141 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_1952 55fb5a8b19c5b3fd9bebd1c080c5a15b 396 Pfam PF00155 Aminotransferase class I and II 50 387 1.9E-39 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 NPD12_1025 7207bc77b2ffbd861412caeb91f77ba7 164 SUPERFAMILY SSF50475 1 155 1.1E-46 T 12-10-2018 NPD12_1025 7207bc77b2ffbd861412caeb91f77ba7 164 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 152 3.4E-21 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related NPD12_1025 7207bc77b2ffbd861412caeb91f77ba7 164 Gene3D G3DSA:2.30.110.10 2 154 9.8E-38 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_3344 ab04c9057e45a9ce02cae3f5ad7ff168 261 Pfam PF01261 Xylose isomerase-like TIM barrel 23 204 6.6E-15 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain NPD12_3344 ab04c9057e45a9ce02cae3f5ad7ff168 261 Gene3D G3DSA:3.20.20.150 1 260 8.8E-38 T 12-10-2018 NPD12_3344 ab04c9057e45a9ce02cae3f5ad7ff168 261 SUPERFAMILY SSF51658 1 257 4.1E-43 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily NPD12_1783 4359d3be72f8c4540f682f44f3e0688f 284 TIGRFAM TIGR00277 HDIG: HDIG domain 116 212 9.8E-9 T 12-10-2018 IPR006675 HDIG domain NPD12_1783 4359d3be72f8c4540f682f44f3e0688f 284 Pfam PF08668 HDOD domain 16 213 9.2E-63 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD NPD12_1783 4359d3be72f8c4540f682f44f3e0688f 284 Gene3D G3DSA:1.10.3210.10 1 280 1.4E-77 T 12-10-2018 NPD12_1783 4359d3be72f8c4540f682f44f3e0688f 284 SUPERFAMILY SSF109604 5 276 1.55E-70 T 12-10-2018 NPD12_1293 43b8dd44ab591fd2a944dd12aabafedb 456 Gene3D G3DSA:3.40.605.10 13 428 1.8E-174 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 NPD12_1293 43b8dd44ab591fd2a944dd12aabafedb 456 PIRSF PIRSF036492 1 456 1.3E-189 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 NPD12_1293 43b8dd44ab591fd2a944dd12aabafedb 456 Gene3D G3DSA:3.40.309.10 213 408 1.8E-174 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 NPD12_1293 43b8dd44ab591fd2a944dd12aabafedb 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 237 248 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 NPD12_1293 43b8dd44ab591fd2a944dd12aabafedb 456 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 209 216 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 NPD12_1293 43b8dd44ab591fd2a944dd12aabafedb 456 Pfam PF00171 Aldehyde dehydrogenase family 4 428 4.0E-83 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 NPD12_1293 43b8dd44ab591fd2a944dd12aabafedb 456 SUPERFAMILY SSF53720 4 437 5.24E-118 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 NPD12_3284 923bdedd657fc4391d8ee6378fd7ef7a 115 SUPERFAMILY SSF48452 3 108 2.55E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3284 923bdedd657fc4391d8ee6378fd7ef7a 115 SMART SM00028 68 100 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3284 923bdedd657fc4391d8ee6378fd7ef7a 115 SMART SM00028 34 67 0.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3284 923bdedd657fc4391d8ee6378fd7ef7a 115 SMART SM00028 1 33 0.078 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_3284 923bdedd657fc4391d8ee6378fd7ef7a 115 Gene3D G3DSA:1.25.40.10 1 114 2.1E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_3284 923bdedd657fc4391d8ee6378fd7ef7a 115 Pfam PF13424 Tetratricopeptide repeat 3 61 3.1E-9 T 12-10-2018 NPD12_1955 b5d8b68ca4da397a6ca202d5da4a9c3b 288 Pfam PF00583 Acetyltransferase (GNAT) family 194 275 4.8E-11 T 12-10-2018 IPR000182 GNAT domain NPD12_1955 b5d8b68ca4da397a6ca202d5da4a9c3b 288 SUPERFAMILY SSF55729 100 278 5.49E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1955 b5d8b68ca4da397a6ca202d5da4a9c3b 288 Gene3D G3DSA:3.40.630.30 138 285 6.7E-19 T 12-10-2018 NPD12_750 98075c1ba5833ff1c8c6f39a6ca51300 116 Gene3D G3DSA:2.40.50.140 3 116 2.9E-28 T 12-10-2018 NPD12_750 98075c1ba5833ff1c8c6f39a6ca51300 116 Pfam PF01588 Putative tRNA binding domain 19 114 2.0E-17 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 NPD12_750 98075c1ba5833ff1c8c6f39a6ca51300 116 SUPERFAMILY SSF50249 7 115 1.22E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold NPD12_2035 7bf78f399babd1f1bba11973b27800f3 83 SUPERFAMILY SSF46689 2 81 1.97E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_598 fb3f1b1e378a5aea92f731ad52612a7c 216 SMART SM00028 127 160 1.1E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_598 fb3f1b1e378a5aea92f731ad52612a7c 216 SMART SM00028 168 202 77.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 NPD12_598 fb3f1b1e378a5aea92f731ad52612a7c 216 Gene3D G3DSA:1.25.40.10 5 214 1.7E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_598 fb3f1b1e378a5aea92f731ad52612a7c 216 SUPERFAMILY SSF48452 79 212 1.81E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_434 3c9bb0c818b09353e6c3243b77a4e194 83 Gene3D G3DSA:3.30.43.10 3 80 6.6E-28 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 NPD12_434 3c9bb0c818b09353e6c3243b77a4e194 83 SUPERFAMILY SSF56176 6 82 7.48E-16 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_434 3c9bb0c818b09353e6c3243b77a4e194 83 Pfam PF01565 FAD binding domain 27 82 3.6E-12 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 NPD12_1269 727ad890e64d10608b58f87f5b4861ce 126 SMART SM00116 74 122 8.7E-8 T 12-10-2018 IPR000644 CBS domain NPD12_1269 727ad890e64d10608b58f87f5b4861ce 126 SMART SM00116 9 57 1.2E-6 T 12-10-2018 IPR000644 CBS domain NPD12_1269 727ad890e64d10608b58f87f5b4861ce 126 SUPERFAMILY SSF54631 4 121 7.83E-32 T 12-10-2018 NPD12_1269 727ad890e64d10608b58f87f5b4861ce 126 Pfam PF00571 CBS domain 4 57 4.9E-13 T 12-10-2018 IPR000644 CBS domain NPD12_1269 727ad890e64d10608b58f87f5b4861ce 126 Pfam PF00571 CBS domain 70 121 1.1E-10 T 12-10-2018 IPR000644 CBS domain NPD12_1269 727ad890e64d10608b58f87f5b4861ce 126 Gene3D G3DSA:3.10.580.10 2 125 1.6E-34 T 12-10-2018 NPD12_2577 9bad329a90b6af36c605c2dbee8802c0 139 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 139 74.916 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 NPD12_2577 9bad329a90b6af36c605c2dbee8802c0 139 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 135 2.5E-53 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 NPD12_2577 9bad329a90b6af36c605c2dbee8802c0 139 Pfam PF03477 ATP cone domain 38 124 4.1E-19 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 NPD12_1450 d18514f0552dc6831ad71ab8952b7b06 43 Pfam PF04723 Glycine reductase complex selenoprotein A 4 43 7.6E-19 T 12-10-2018 IPR006812 Glycine reductase complex selenoprotein A GO:0030699|GO:0030700|GO:0050485|GO:0055114 NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 Gene3D G3DSA:2.60.40.10 450 538 7.6E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 Gene3D G3DSA:2.60.40.10 539 633 2.6E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 SUPERFAMILY SSF81296 644 735 1.3E-21 T 12-10-2018 IPR014756 Immunoglobulin E-set NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 Pfam PF08329 Chitinase A, N-terminal domain 660 735 1.4E-5 T 12-10-2018 IPR013540 Chitinase A N-terminal GO:0004568|GO:0006032 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 SMART SM00636 43 424 2.5E-125 T 12-10-2018 IPR011583 Chitinase II GO:0008061 NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 Gene3D G3DSA:3.10.50.10 315 395 3.5E-114 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 SUPERFAMILY SSF51445 42 453 2.42E-93 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 SUPERFAMILY SSF81296 548 635 1.11E-13 T 12-10-2018 IPR014756 Immunoglobulin E-set NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 Gene3D G3DSA:3.20.20.80 46 425 3.5E-114 T 12-10-2018 NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 Gene3D G3DSA:2.60.40.10 654 735 2.8E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 SUPERFAMILY SSF54556 316 395 2.01E-8 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 SUPERFAMILY SSF81296 430 542 3.92E-13 T 12-10-2018 IPR014756 Immunoglobulin E-set NPD12_2860 e8337dce57a5fe33f34f36008db207c2 739 Pfam PF00704 Glycosyl hydrolases family 18 44 424 6.1E-89 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 NPD12_2498 3c3599cd3b8e7ba61845ae5fbf8fb237 104 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 1 92 8.0E-28 T 12-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like NPD12_2498 3c3599cd3b8e7ba61845ae5fbf8fb237 104 Hamap MF_00245 UPF0122 protein . 1 100 15.935 T 12-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like NPD12_2498 3c3599cd3b8e7ba61845ae5fbf8fb237 104 SUPERFAMILY SSF88659 1 87 5.98E-28 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_2498 3c3599cd3b8e7ba61845ae5fbf8fb237 104 Gene3D G3DSA:1.10.10.10 1 100 7.3E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1600 d51d8cf31960c88c8099d4f2cd57dc53 191 SUPERFAMILY SSF90123 19 102 2.22E-10 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1600 d51d8cf31960c88c8099d4f2cd57dc53 191 Gene3D G3DSA:3.40.50.300 103 191 4.5E-21 T 12-10-2018 NPD12_1600 d51d8cf31960c88c8099d4f2cd57dc53 191 SUPERFAMILY SSF52540 110 190 2.34E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1600 d51d8cf31960c88c8099d4f2cd57dc53 191 Gene3D G3DSA:1.20.1560.10 2 102 2.3E-9 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 NPD12_1600 d51d8cf31960c88c8099d4f2cd57dc53 191 Pfam PF00005 ABC transporter 132 191 8.2E-12 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 SUPERFAMILY SSF52242 43 104 1.22E-5 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 Pfam PF04055 Radical SAM superfamily 178 338 1.9E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 SMART SM00729 173 386 5.4E-35 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 Pfam PF02310 B12 binding domain 6 122 3.5E-20 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 Pfam PF13311 Protein of unknown function (DUF4080) 366 541 6.3E-45 T 12-10-2018 IPR025288 Domain of unknown function DUF4080 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 Gene3D G3DSA:3.40.50.280 11 138 1.5E-10 T 12-10-2018 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 SUPERFAMILY SSF102114 163 374 1.44E-45 T 12-10-2018 NPD12_2680 704c690472dbf895f6f7a9e46408396a 561 Gene3D G3DSA:3.80.30.20 171 357 2.7E-24 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_794 e3edaeaa2b309a51138abea85186e9f7 343 SMART SM00418 262 340 2.1E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_794 e3edaeaa2b309a51138abea85186e9f7 343 SUPERFAMILY SSF46785 263 337 5.01E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_794 e3edaeaa2b309a51138abea85186e9f7 343 Gene3D G3DSA:1.10.10.10 257 342 1.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_794 e3edaeaa2b309a51138abea85186e9f7 343 Pfam PF01022 Bacterial regulatory protein, arsR family 269 310 3.6E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_794 e3edaeaa2b309a51138abea85186e9f7 343 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 296 311 1.6E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_794 e3edaeaa2b309a51138abea85186e9f7 343 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 264 279 1.6E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_794 e3edaeaa2b309a51138abea85186e9f7 343 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 311 326 1.6E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_653 948c66386ed819d9cb66132c37a81c49 57 TIGRFAM TIGR03602 streptolysinS: bacteriocin protoxin, streptolysin S family 1 56 2.6E-33 T 12-10-2018 IPR019891 Bacteriocin, streptolysin S, precursor NPD12_58 c9ce731dd879a6f947fd0b2b581c7e5d 143 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 138 6.5E-31 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_2954 b4c0a17efaf39830ae68f32db205a550 480 Pfam PF00860 Permease family 34 439 4.9E-40 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 NPD12_2954 b4c0a17efaf39830ae68f32db205a550 480 PIRSF PIRSF005353 8 480 4.3E-197 T 12-10-2018 IPR026033 Purine permease PbuG-like NPD12_2138 5d14e46f2e97bad417c87af38736a922 500 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 15 475 2.5E-159 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 NPD12_2138 5d14e46f2e97bad417c87af38736a922 500 PIRSF PIRSF005690 1 490 6.7E-180 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 NPD12_1602 eb6e229d4ebdfef8804b0429aa2774f3 104 ProDom PD075772 YGBA ECS3588 CYTOPLASMIC UVRA STM2860 AMIDOPHOSPHORIBOSYLTRANSFERASE VVA0912 SO0324 VPA0976 CPE0229 1 98 6.0E-20 T 12-10-2018 IPR020483 Uncharacterised protein family YgbA NPD12_1602 eb6e229d4ebdfef8804b0429aa2774f3 104 Pfam PF11756 Nitrous oxide-stimulated promoter 5 102 3.6E-36 T 12-10-2018 IPR020483 Uncharacterised protein family YgbA NPD12_1033 7aec8aab0a64d500d6619ab742a7340c 217 Pfam PF13599 Pentapeptide repeats (9 copies) 92 165 1.1E-10 T 12-10-2018 IPR001646 Pentapeptide repeat NPD12_1033 7aec8aab0a64d500d6619ab742a7340c 217 SUPERFAMILY SSF141571 38 215 4.32E-39 T 12-10-2018 NPD12_1033 7aec8aab0a64d500d6619ab742a7340c 217 Gene3D G3DSA:2.160.20.100 4 216 8.8E-41 T 12-10-2018 NPD12_858 021767054b994c184b5f498f1b012e45 290 Pfam PF14261 Domain of unknown function (DUF4351) 233 289 2.2E-11 T 12-10-2018 IPR025587 Domain of unknown function DUF4351 NPD12_2663 483ea1f0af92e343b8ce951ad6bc388d 324 Gene3D G3DSA:3.40.190.90 124 288 1.6E-130 T 12-10-2018 NPD12_2663 483ea1f0af92e343b8ce951ad6bc388d 324 PIRSF PIRSF004532 2 323 1.3E-137 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 NPD12_2663 483ea1f0af92e343b8ce951ad6bc388d 324 SUPERFAMILY SSF56655 3 316 3.62E-101 T 12-10-2018 NPD12_2663 483ea1f0af92e343b8ce951ad6bc388d 324 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 5 314 2.0E-135 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 NPD12_2663 483ea1f0af92e343b8ce951ad6bc388d 324 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 3 320 5.3E-114 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 NPD12_2663 483ea1f0af92e343b8ce951ad6bc388d 324 Gene3D G3DSA:3.30.540.10 6 314 1.6E-130 T 12-10-2018 NPD12_2578 3bd549cd78cb3d3fb9592206735d6e02 87 Pfam PF05239 PRC-barrel domain 7 80 3.3E-13 T 12-10-2018 IPR027275 PRC-barrel domain NPD12_2578 3bd549cd78cb3d3fb9592206735d6e02 87 Gene3D G3DSA:2.30.30.240 7 81 5.6E-6 T 12-10-2018 NPD12_2578 3bd549cd78cb3d3fb9592206735d6e02 87 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 9 78 1.1E-23 T 12-10-2018 IPR014238 Sporulation protein YlmC/YmxH NPD12_2578 3bd549cd78cb3d3fb9592206735d6e02 87 SUPERFAMILY SSF50346 6 78 1.6E-12 T 12-10-2018 IPR011033 PRC-barrel-like superfamily NPD12_1719 f5cd522a3b0d1ea339f25a083de3bb1b 219 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.2E-17 T 12-10-2018 IPR019933 DivIVA domain NPD12_1719 f5cd522a3b0d1ea339f25a083de3bb1b 219 Pfam PF05103 DivIVA protein 3 133 7.4E-48 T 12-10-2018 IPR007793 DivIVA family NPD12_1823 7d6f88ecc49c93ce93c3a96dacbdb63d 243 TIGRFAM TIGR03732 lanti_perm_MutE: lantibiotic protection ABC transporter permease subunit, MutE/EpiE family 3 242 3.1E-97 T 12-10-2018 IPR021205 Lantibiotic ABC transporter permease subunit, SpaE/MutE NPD12_737 3c1812593c510313983aa8c1e2d4426a 319 Gene3D G3DSA:1.10.3720.10 43 310 3.8E-56 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_737 3c1812593c510313983aa8c1e2d4426a 319 SUPERFAMILY SSF161098 44 307 2.43E-56 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_737 3c1812593c510313983aa8c1e2d4426a 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 304 8.1E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_2334 56fbce6796683ba3b9a2903de7b33abb 297 Pfam PF02517 CAAX protease self-immunity 138 229 3.3E-16 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_2946 799f312107baa4d7cb412f92d76ff7f1 181 Gene3D G3DSA:3.40.50.300 2 166 1.3E-30 T 12-10-2018 NPD12_2946 799f312107baa4d7cb412f92d76ff7f1 181 Pfam PF03266 NTPase 3 162 2.8E-41 T 12-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 NPD12_2946 799f312107baa4d7cb412f92d76ff7f1 181 SUPERFAMILY SSF52540 3 168 7.61E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1674 4898a5cf130adb12dac2798cd6ab9525 506 Pfam PF03606 C4-dicarboxylate anaerobic carrier 10 502 1.0E-137 T 12-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 6.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 6.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 6.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 6.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 Pfam PF01047 MarR family 35 93 5.6E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 SMART SM00347 28 128 2.1E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 Gene3D G3DSA:1.10.10.10 7 158 7.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_74 c88eae5442d3737b69bacf9ec5b2b5d6 158 SUPERFAMILY SSF46785 11 144 4.28E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF11738 Protein of unknown function (DUF3298) 732 807 4.1E-18 T 12-10-2018 IPR021729 Domain of unknown function DUF3298 NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Gene3D G3DSA:1.25.40.10 138 262 4.0E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 SUPERFAMILY SSF48452 183 232 2.18E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF14903 WG containing repeat 416 447 0.062 T 12-10-2018 IPR032774 WG containing repeat NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF14903 WG containing repeat 452 482 1.4E-8 T 12-10-2018 IPR032774 WG containing repeat NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF14903 WG containing repeat 342 368 0.23 T 12-10-2018 IPR032774 WG containing repeat NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF14903 WG containing repeat 381 412 1.8E-8 T 12-10-2018 IPR032774 WG containing repeat NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF14903 WG containing repeat 490 509 1.9E-4 T 12-10-2018 IPR032774 WG containing repeat NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF14903 WG containing repeat 271 306 2.7E-7 T 12-10-2018 IPR032774 WG containing repeat NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Pfam PF14903 WG containing repeat 306 334 0.0021 T 12-10-2018 IPR032774 WG containing repeat NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Gene3D G3DSA:3.30.565.40 622 728 4.1E-9 T 12-10-2018 NPD12_1189 f440f4f30fe5866084b0e838628b5975 824 Gene3D G3DSA:3.90.640.20 730 820 1.4E-22 T 12-10-2018 IPR037126 PdaC/RsiV-like superfamily NPD12_631 3ad71759443dc7f84b5eade861731999 283 Pfam PF04536 TPM domain 45 164 5.1E-35 T 12-10-2018 IPR007621 TPM domain NPD12_631 3ad71759443dc7f84b5eade861731999 283 Gene3D G3DSA:3.10.310.50 30 176 1.8E-45 T 12-10-2018 NPD12_2382 37a6d2a86f95b32c6026a7071cab343b 186 PIRSF PIRSF016661 1 186 3.6E-40 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 NPD12_2382 37a6d2a86f95b32c6026a7071cab343b 186 Gene3D G3DSA:1.10.1760.20 1 181 4.1E-48 T 12-10-2018 NPD12_2382 37a6d2a86f95b32c6026a7071cab343b 186 Pfam PF02632 BioY family 35 176 1.6E-31 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 NPD12_2230 f8377660a64b076ef0c35aaf21f2762e 307 Gene3D G3DSA:3.40.50.720 3 234 3.0E-105 T 12-10-2018 NPD12_2230 f8377660a64b076ef0c35aaf21f2762e 307 Gene3D G3DSA:3.90.25.10 172 299 3.0E-105 T 12-10-2018 NPD12_2230 f8377660a64b076ef0c35aaf21f2762e 307 SUPERFAMILY SSF51735 1 305 5.93E-95 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2230 f8377660a64b076ef0c35aaf21f2762e 307 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 297 4.5E-56 T 12-10-2018 IPR016040 NAD(P)-binding domain NPD12_2204 ea09842ec1718bc931b1e050bc9d5c2e 336 Pfam PF00535 Glycosyl transferase family 2 36 198 1.9E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_2204 ea09842ec1718bc931b1e050bc9d5c2e 336 SUPERFAMILY SSF53448 36 219 9.52E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2204 ea09842ec1718bc931b1e050bc9d5c2e 336 Gene3D G3DSA:3.90.550.10 33 227 7.3E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_3126 12f6b40e2c84922a907d148ffebe2020 259 SUPERFAMILY SSF49785 11 152 5.65E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_3126 12f6b40e2c84922a907d148ffebe2020 259 Gene3D G3DSA:2.60.120.260 12 162 7.6E-19 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_3126 12f6b40e2c84922a907d148ffebe2020 259 Pfam PF00754 F5/8 type C domain 22 150 4.5E-7 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain NPD12_1586 01b84e1cc792b8297ce6b948b584a09a 195 Gene3D G3DSA:1.20.1260.10 1 150 1.4E-55 T 12-10-2018 IPR012347 Ferritin-like NPD12_1586 01b84e1cc792b8297ce6b948b584a09a 195 Gene3D G3DSA:2.20.28.10 151 195 4.2E-19 T 12-10-2018 NPD12_1586 01b84e1cc792b8297ce6b948b584a09a 195 SUPERFAMILY SSF47240 5 151 2.71E-40 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_1586 01b84e1cc792b8297ce6b948b584a09a 195 Pfam PF02915 Rubrerythrin 11 143 2.0E-28 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 NPD12_1586 01b84e1cc792b8297ce6b948b584a09a 195 SUPERFAMILY SSF57802 152 194 1.76E-11 T 12-10-2018 NPD12_253 39ae1f7c55bab68881666fa0bf5bcf85 212 SUPERFAMILY SSF56281 1 185 9.42E-24 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_253 39ae1f7c55bab68881666fa0bf5bcf85 212 Pfam PF13483 Beta-lactamase superfamily domain 2 162 2.1E-44 T 12-10-2018 NPD12_253 39ae1f7c55bab68881666fa0bf5bcf85 212 Gene3D G3DSA:3.60.15.10 1 211 7.9E-55 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_706 be13e000b23e5af42fb2a8d38d737415 290 Gene3D G3DSA:3.60.15.10 27 269 1.1E-62 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_706 be13e000b23e5af42fb2a8d38d737415 290 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 81 100 - T 12-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 NPD12_706 be13e000b23e5af42fb2a8d38d737415 290 SMART SM00849 39 231 1.1E-4 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_706 be13e000b23e5af42fb2a8d38d737415 290 Pfam PF00753 Metallo-beta-lactamase superfamily 38 104 1.8E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_706 be13e000b23e5af42fb2a8d38d737415 290 SUPERFAMILY SSF56281 31 268 1.7E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_3299 2ec2dbaf818bb3ded807fdefc86743b1 578 Gene3D G3DSA:3.40.50.410 405 571 1.0E-11 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily NPD12_3299 2ec2dbaf818bb3ded807fdefc86743b1 578 Pfam PF13519 von Willebrand factor type A domain 405 508 1.3E-9 T 12-10-2018 IPR002035 von Willebrand factor, type A NPD12_3299 2ec2dbaf818bb3ded807fdefc86743b1 578 SUPERFAMILY SSF53300 405 567 4.61E-14 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily NPD12_3299 2ec2dbaf818bb3ded807fdefc86743b1 578 SMART SM00327 402 575 9.9E-10 T 12-10-2018 IPR002035 von Willebrand factor, type A NPD12_3114 0d248239f19967933f1e05320d8b0174 184 SUPERFAMILY SSF54506 2 134 6.54E-24 T 12-10-2018 NPD12_3114 0d248239f19967933f1e05320d8b0174 184 Pfam PF02567 Phenazine biosynthesis-like protein 6 103 3.5E-17 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 NPD12_3114 0d248239f19967933f1e05320d8b0174 184 Gene3D G3DSA:3.10.310.10 1 122 4.6E-28 T 12-10-2018 NPD12_575 23ebe04df15db84d53ae826707826c39 437 Pfam PF08245 Mur ligase middle domain 41 270 1.8E-16 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 NPD12_575 23ebe04df15db84d53ae826707826c39 437 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 39 63 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 NPD12_575 23ebe04df15db84d53ae826707826c39 437 Pfam PF08353 Domain of unknown function (DUF1727) 310 420 1.5E-38 T 12-10-2018 IPR013564 Domain of unknown function DUF1727 NPD12_575 23ebe04df15db84d53ae826707826c39 437 SUPERFAMILY SSF53623 28 287 2.86E-35 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 NPD12_1484 f62a21fdd9c8f468cdfe56b587d15f9f 191 Pfam PF03592 Terminase small subunit 3 165 3.4E-36 T 12-10-2018 IPR005335 Terminase small subunit GO:0006323 NPD12_1484 f62a21fdd9c8f468cdfe56b587d15f9f 191 Gene3D G3DSA:1.10.10.1400 1 66 5.5E-16 T 12-10-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily NPD12_2283 fd2d3967a5cd8e0f21c05f2ab295d963 663 PIRSF PIRSF018968 1 663 2.0E-69 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 NPD12_2283 fd2d3967a5cd8e0f21c05f2ab295d963 663 Pfam PF02687 FtsX-like permease family 88 184 3.7E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_3806 3f7a4ab7c7ff5beb32181ba16e9c1e97 147 Pfam PF05565 Siphovirus Gp157 3 147 4.0E-44 T 12-10-2018 IPR008840 Siphovirus Gp157 NPD12_1413 72a578d5deaff5b3320aca942f0f3bc9 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 280 7.4E-35 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1413 72a578d5deaff5b3320aca942f0f3bc9 282 Gene3D G3DSA:1.10.3720.10 74 274 7.0E-21 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1413 72a578d5deaff5b3320aca942f0f3bc9 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 51 4.9E-7 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain NPD12_1413 72a578d5deaff5b3320aca942f0f3bc9 282 SUPERFAMILY SSF161098 77 264 1.57E-27 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2288 ddceae428aa044a013672770e6dd27fd 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 75 1.5E-16 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 NPD12_2288 ddceae428aa044a013672770e6dd27fd 94 SUPERFAMILY SSF52794 1 87 4.45E-22 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 NPD12_2288 ddceae428aa044a013672770e6dd27fd 94 Gene3D G3DSA:3.40.50.2300 1 86 4.0E-22 T 12-10-2018 NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 SUPERFAMILY SSF51735 143 279 1.5E-9 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 195 297 3.0E-11 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 SUPERFAMILY SSF52283 1 180 3.32E-27 T 12-10-2018 NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 SMART SM01002 147 273 6.4E-7 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 SMART SM01003 4 111 6.8E-7 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 Gene3D G3DSA:3.40.50.720 139 281 4.6E-36 T 12-10-2018 NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 Gene3D G3DSA:3.40.50.720 4 297 4.6E-36 T 12-10-2018 NPD12_681 e70fb9110f97faeb3d3447ed9152f52f 317 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 10 95 7.7E-16 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal NPD12_3821 a59afdf3e4891994443e3bde42bfeebe 393 Gene3D G3DSA:3.30.930.30 2 185 7.3E-65 T 12-10-2018 NPD12_3821 a59afdf3e4891994443e3bde42bfeebe 393 Pfam PF01076 Plasmid recombination enzyme 3 192 1.8E-61 T 12-10-2018 IPR001668 Plasmid recombination enzyme GO:0003677|GO:0005727|GO:0006310 NPD12_1578 e9ff9dfaa07a63e2f48352ea10e429a3 252 Pfam PF01478 Type IV leader peptidase family 101 206 1.0E-10 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 NPD12_1578 e9ff9dfaa07a63e2f48352ea10e429a3 252 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 7 88 8.4E-34 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal NPD12_6 0118434afaee472813da8af121acdbbf 511 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 354 497 8.2E-26 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain NPD12_6 0118434afaee472813da8af121acdbbf 511 Pfam PF01943 Polysaccharide biosynthesis protein 6 301 5.1E-37 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 NPD12_6 0118434afaee472813da8af121acdbbf 511 PIRSF PIRSF038958 1 511 6.4E-155 T 12-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type NPD12_120 7b0dd7a6c220ec77c143ba9802acb147 239 Pfam PF02527 rRNA small subunit methyltransferase G 23 202 1.3E-55 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 NPD12_120 7b0dd7a6c220ec77c143ba9802acb147 239 Gene3D G3DSA:3.40.50.150 2 239 4.4E-82 T 12-10-2018 NPD12_120 7b0dd7a6c220ec77c143ba9802acb147 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 218 1.4E-56 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 NPD12_120 7b0dd7a6c220ec77c143ba9802acb147 239 SUPERFAMILY SSF53335 5 239 2.07E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_120 7b0dd7a6c220ec77c143ba9802acb147 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 15 215 28.419 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 NPD12_120 7b0dd7a6c220ec77c143ba9802acb147 239 PIRSF PIRSF003078 1 221 2.1E-58 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 NPD12_2935 0dba8006cbf34d285b65d305ea7a765d 442 SUPERFAMILY SSF51338 1 439 1.94E-35 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2935 0dba8006cbf34d285b65d305ea7a765d 442 SUPERFAMILY SSF51556 59 348 2.07E-74 T 12-10-2018 IPR032466 Metal-dependent hydrolase NPD12_2935 0dba8006cbf34d285b65d305ea7a765d 442 TIGRFAM TIGR03314 Se_ssnA: putative selenium metabolism protein SsnA 2 442 2.4E-229 T 12-10-2018 IPR017700 Putative aminohydrolase SsnA NPD12_2935 0dba8006cbf34d285b65d305ea7a765d 442 Gene3D G3DSA:2.30.40.10 3 430 8.1E-116 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 NPD12_2935 0dba8006cbf34d285b65d305ea7a765d 442 Pfam PF01979 Amidohydrolase family 56 412 1.0E-44 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 NPD12_2935 0dba8006cbf34d285b65d305ea7a765d 442 Gene3D G3DSA:3.20.20.140 60 355 8.1E-116 T 12-10-2018 NPD12_153 cc1a74fc6a931f14917ab803e8c10e12 295 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 77 278 2.7E-44 T 12-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 NPD12_153 cc1a74fc6a931f14917ab803e8c10e12 295 Hamap MF_00663 Phosphatidylserine decarboxylase proenzyme [psd]. 1 294 43.652 T 12-10-2018 IPR033179 Phosphatidylserine decarboxylase, prokaryotic type 2 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 NPD12_153 cc1a74fc6a931f14917ab803e8c10e12 295 Pfam PF02666 Phosphatidylserine decarboxylase 86 292 2.6E-57 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 NPD12_2624 42793bd3d265d66344da6705172ebde1 217 Pfam PF14344 Domain of unknown function (DUF4397) 21 137 4.4E-28 T 12-10-2018 IPR025510 Domain of unknown function DUF4397 NPD12_2624 42793bd3d265d66344da6705172ebde1 217 Pfam PF14344 Domain of unknown function (DUF4397) 120 205 1.5E-19 T 12-10-2018 IPR025510 Domain of unknown function DUF4397 NPD12_3121 d9849f239fbfdf80cc39c9c9317acfe0 259 SUPERFAMILY SSF53187 3 173 3.45E-31 T 12-10-2018 NPD12_3121 d9849f239fbfdf80cc39c9c9317acfe0 259 SMART SM00646 67 171 2.9E-13 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3121 d9849f239fbfdf80cc39c9c9317acfe0 259 Pfam PF08239 Bacterial SH3 domain 204 255 1.5E-10 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_3121 d9849f239fbfdf80cc39c9c9317acfe0 259 SMART SM00287 196 258 2.8E-7 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_3121 d9849f239fbfdf80cc39c9c9317acfe0 259 Gene3D G3DSA:3.40.630.40 1 175 6.4E-40 T 12-10-2018 NPD12_3121 d9849f239fbfdf80cc39c9c9317acfe0 259 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 170 3.6E-24 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_3121 d9849f239fbfdf80cc39c9c9317acfe0 259 Gene3D G3DSA:2.30.30.40 195 254 3.7E-15 T 12-10-2018 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 7.2E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 7.2E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 7.2E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 PRINTS PR00412 Epoxide hydrolase signature 213 229 1.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 PRINTS PR00412 Epoxide hydrolase signature 246 268 1.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 PRINTS PR00412 Epoxide hydrolase signature 50 65 1.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 PRINTS PR00412 Epoxide hydrolase signature 30 48 1.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 Gene3D G3DSA:3.40.50.1820 1 270 1.3E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 SUPERFAMILY SSF53474 9 270 1.71E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2119 cdb1f03cfedc29b44aa227145b8491dd 271 Pfam PF00561 alpha/beta hydrolase fold 25 124 2.2E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 NPD12_2177 04853b97b885367e6229aadcca312291 272 Gene3D G3DSA:3.40.190.10 137 229 4.7E-74 T 12-10-2018 NPD12_2177 04853b97b885367e6229aadcca312291 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 47 263 4.1E-59 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_2177 04853b97b885367e6229aadcca312291 272 Gene3D G3DSA:3.40.190.10 44 262 4.7E-74 T 12-10-2018 NPD12_2177 04853b97b885367e6229aadcca312291 272 SMART SM00062 46 267 1.1E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF NPD12_2177 04853b97b885367e6229aadcca312291 272 SUPERFAMILY SSF53850 9 263 6.96E-64 T 12-10-2018 NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 SUPERFAMILY SSF46785 15 142 1.22E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 SMART SM00347 29 129 2.9E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 Pfam PF01047 MarR family 37 93 2.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2098 da2025dd38b74f8841a2fb28403442ac 147 Gene3D G3DSA:1.10.10.10 1 140 7.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 SUPERFAMILY SSF55252 79 146 1.7E-15 T 12-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 Pfam PF02863 Arginine repressor, C-terminal domain 79 145 1.8E-21 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 Gene3D G3DSA:3.30.1360.40 68 148 2.3E-21 T 12-10-2018 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 TIGRFAM TIGR01529 argR_whole: arginine repressor 4 147 2.7E-40 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 91 140 7.0E-11 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 Gene3D G3DSA:1.10.10.10 3 65 6.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 SUPERFAMILY SSF46785 2 74 1.85E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 Hamap MF_00173 Arginine repressor [argR]. 1 150 56.564 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 Pfam PF01316 Arginine repressor, DNA binding domain 2 67 1.1E-23 T 12-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 PRINTS PR01467 Bacterial arginine repressor signature 117 132 7.7E-20 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 PRINTS PR01467 Bacterial arginine repressor signature 36 51 7.7E-20 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 PRINTS PR01467 Bacterial arginine repressor signature 20 33 7.7E-20 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 NPD12_2044 c3c9f806356cbeadd6ae07b295a8e5c8 150 PRINTS PR01467 Bacterial arginine repressor signature 87 100 7.7E-20 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 Gene3D G3DSA:1.10.287.950 355 662 6.0E-59 T 12-10-2018 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 514 543 6.9E-5 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 6.9E-5 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 461 615 6.3E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 Gene3D G3DSA:3.30.450.20 97 183 4.8E-36 T 12-10-2018 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 SUPERFAMILY SSF58104 387 662 3.4E-58 T 12-10-2018 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 Pfam PF02743 Cache domain 42 265 5.6E-35 T 12-10-2018 IPR033479 Double Cache domain 1 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 SUPERFAMILY SSF103190 86 190 6.8E-12 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 SMART SM00283 387 662 1.2E-50 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_724 a43496cdad30fa1532851b6a23a03cfc 663 Gene3D G3DSA:3.30.450.20 184 277 4.8E-36 T 12-10-2018 NPD12_2532 d3cd1556bb23c7dc37174b7a1575e3f6 434 Gene3D G3DSA:3.40.50.11540 89 234 9.7E-18 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2532 d3cd1556bb23c7dc37174b7a1575e3f6 434 SUPERFAMILY SSF142984 254 309 1.09E-5 T 12-10-2018 NPD12_2532 d3cd1556bb23c7dc37174b7a1575e3f6 434 Pfam PF13375 RnfC Barrel sandwich hybrid domain 3 61 6.2E-13 T 12-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain NPD12_2532 d3cd1556bb23c7dc37174b7a1575e3f6 434 TIGRFAM TIGR04481 PR_assoc_PrdC: proline reductase-associated electron transfer protein PrdC 5 429 1.3E-199 T 12-10-2018 IPR031001 Proline reductase-associated electron transfer protein PrdC NPD12_2532 d3cd1556bb23c7dc37174b7a1575e3f6 434 SUPERFAMILY SSF142019 42 245 2.35E-50 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2532 d3cd1556bb23c7dc37174b7a1575e3f6 434 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 84 227 1.5E-42 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 Gene3D G3DSA:1.10.10.10 221 313 1.1E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 106 6.5E-28 T 12-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 Pfam PF14527 WhiA LAGLIDADG-like domain 131 222 2.9E-38 T 12-10-2018 IPR039518 WhiA, LAGLIDADG-like domain NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 Gene3D G3DSA:3.10.28.10 1 220 7.4E-63 T 12-10-2018 IPR027434 Homing endonuclease NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 5 309 4.8E-113 T 12-10-2018 IPR033981 Sporulation regulator WhiA-like NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 311 35.014 T 12-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 Pfam PF02650 WhiA C-terminal HTH domain 225 308 8.3E-37 T 12-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal NPD12_3530 c34bf99c32573aab8d9205ac2ca97f01 315 SUPERFAMILY SSF55608 119 226 4.86E-21 T 12-10-2018 IPR027434 Homing endonuclease NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 Gene3D G3DSA:3.40.630.10 332 478 1.1E-23 T 12-10-2018 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PIRSF PIRSF016599 1 478 4.1E-190 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 SUPERFAMILY SSF53187 9 477 1.2E-58 T 12-10-2018 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 157 175 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 202 219 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 247 266 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 445 467 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 133 150 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 423 439 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 359 377 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 99 117 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 PRINTS PR00934 X-His dipeptidase (M25) signature 78 97 1.2E-50 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 Gene3D G3DSA:3.40.630.10 1 228 1.6E-60 T 12-10-2018 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 5 478 1.1E-184 T 12-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 Pfam PF07687 Peptidase dimerisation domain 202 286 5.3E-7 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain NPD12_2922 c23d082942e2b5129ebcf1e5c75ef2fb 478 Pfam PF01546 Peptidase family M20/M25/M40 71 476 4.2E-20 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 SMART SM00422 1 70 8.8E-24 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 Pfam PF13411 MerR HTH family regulatory protein 1 68 1.1E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 SUPERFAMILY SSF46955 1 114 1.14E-29 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 Gene3D G3DSA:1.10.1660.10 1 119 1.8E-31 T 12-10-2018 NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.7E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.7E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_2304 bfaf923be60e7eb2f267084073cddab2 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.7E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_927 94702b2cef8f0ab1c50056976c00ce6b 276 Pfam PF00149 Calcineurin-like phosphoesterase 38 196 9.9E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 NPD12_927 94702b2cef8f0ab1c50056976c00ce6b 276 SUPERFAMILY SSF56300 37 212 4.11E-19 T 12-10-2018 NPD12_927 94702b2cef8f0ab1c50056976c00ce6b 276 Gene3D G3DSA:3.60.21.10 27 264 8.7E-13 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like NPD12_1223 9afb8ab9849f6bf5114ad9afff625ca7 48 Pfam PF12669 Virus attachment protein p12 family 2 42 2.4E-10 T 12-10-2018 NPD12_1381 b4cb8a661916cb233837767ee73a0f20 153 Gene3D G3DSA:2.40.30.100 2 85 1.0E-30 T 12-10-2018 IPR037079 AF2212/PG0164-like superfamily NPD12_1381 b4cb8a661916cb233837767ee73a0f20 153 SUPERFAMILY SSF141694 3 85 2.35E-23 T 12-10-2018 NPD12_1381 b4cb8a661916cb233837767ee73a0f20 153 Pfam PF08922 Domain of unknown function (DUF1905) 6 83 2.2E-19 T 12-10-2018 IPR015018 Protein of unknown function DUF1905 NPD12_1381 b4cb8a661916cb233837767ee73a0f20 153 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 92 149 2.2E-17 T 12-10-2018 NPD12_2769 33f0ada7f497db84dd457dd8a9b1a75e 118 SUPERFAMILY SSF160214 40 118 4.45E-22 T 12-10-2018 IPR035924 FlaG-like superfamily NPD12_2769 33f0ada7f497db84dd457dd8a9b1a75e 118 Pfam PF03646 FlaG protein 28 116 1.9E-20 T 12-10-2018 IPR005186 FlaG protein NPD12_2769 33f0ada7f497db84dd457dd8a9b1a75e 118 Gene3D G3DSA:3.30.160.170 16 114 1.8E-25 T 12-10-2018 IPR035924 FlaG-like superfamily NPD12_1202 45563540a7fba9a90e8e6a72cfd18185 153 SUPERFAMILY SSF46785 34 148 2.1E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1202 45563540a7fba9a90e8e6a72cfd18185 153 Pfam PF01047 MarR family 36 90 5.3E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1202 45563540a7fba9a90e8e6a72cfd18185 153 SMART SM00347 26 129 2.3E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1202 45563540a7fba9a90e8e6a72cfd18185 153 Gene3D G3DSA:1.10.10.10 3 145 3.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1793 16cc1df4ffeac7ae2aa622f957f89b7a 253 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 244 6.5E-30 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_1793 16cc1df4ffeac7ae2aa622f957f89b7a 253 SUPERFAMILY SSF53067 4 247 1.01E-28 T 12-10-2018 NPD12_1793 16cc1df4ffeac7ae2aa622f957f89b7a 253 Gene3D G3DSA:3.30.420.40 4 246 1.4E-51 T 12-10-2018 NPD12_1793 16cc1df4ffeac7ae2aa622f957f89b7a 253 Gene3D G3DSA:3.30.420.40 96 231 1.4E-51 T 12-10-2018 NPD12_1793 16cc1df4ffeac7ae2aa622f957f89b7a 253 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 4 244 2.2E-47 T 12-10-2018 IPR008275 CoA enzyme activase NPD12_3778 4a51009feeb7abf446d4475252afb764 343 Pfam PF11863 Protein of unknown function (DUF3383) 97 336 1.6E-20 T 12-10-2018 IPR021808 Protein of unknown function DUF3383 NPD12_144 0e5396ce5fbd127d876453a19c5179b6 258 SUPERFAMILY SSF141523 133 256 4.05E-25 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_144 0e5396ce5fbd127d876453a19c5179b6 258 Gene3D G3DSA:2.40.440.10 128 257 5.9E-28 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like NPD12_144 0e5396ce5fbd127d876453a19c5179b6 258 Pfam PF03734 L,D-transpeptidase catalytic domain 135 256 1.1E-19 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 NPD12_865 0a481ac440d4c676cfe8c325fe05444b 261 SMART SM00382 28 217 1.1E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_865 0a481ac440d4c676cfe8c325fe05444b 261 Pfam PF00005 ABC transporter 20 167 1.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_865 0a481ac440d4c676cfe8c325fe05444b 261 Gene3D G3DSA:3.40.50.300 1 255 5.0E-67 T 12-10-2018 NPD12_865 0a481ac440d4c676cfe8c325fe05444b 261 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_865 0a481ac440d4c676cfe8c325fe05444b 261 SUPERFAMILY SSF52540 4 230 8.42E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2635 3fdbf0c6146c6e7024d239076d5d2a0b 82 Gene3D G3DSA:1.10.1200.10 1 81 6.1E-15 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2635 3fdbf0c6146c6e7024d239076d5d2a0b 82 SUPERFAMILY SSF47336 3 78 2.08E-10 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_1601 e581bfdf82a64e15486024edbadac436 97 Gene3D G3DSA:3.40.50.300 1 91 3.6E-31 T 12-10-2018 NPD12_1601 e581bfdf82a64e15486024edbadac436 97 SUPERFAMILY SSF52540 3 91 7.19E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1601 e581bfdf82a64e15486024edbadac436 97 Pfam PF00005 ABC transporter 13 70 3.4E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2963 13872b80fee5d354d57c5fc6bffcfeeb 437 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 4 427 88.815 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 NPD12_2963 13872b80fee5d354d57c5fc6bffcfeeb 437 Gene3D G3DSA:3.20.20.540 46 363 3.8E-138 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 NPD12_2963 13872b80fee5d354d57c5fc6bffcfeeb 437 Pfam PF01964 Radical SAM ThiC family 5 422 4.8E-194 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 NPD12_2963 13872b80fee5d354d57c5fc6bffcfeeb 437 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 5 423 2.4E-180 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 NPD12_2002 aa5f5cdf8e08deaaeeac0a56039b7d1a 159 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 15 157 4.1E-52 T 12-10-2018 NPD12_2002 aa5f5cdf8e08deaaeeac0a56039b7d1a 159 SUPERFAMILY SSF52833 9 157 3.91E-51 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_2002 aa5f5cdf8e08deaaeeac0a56039b7d1a 159 PIRSF PIRSF000216 2 159 1.2E-55 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 NPD12_2002 aa5f5cdf8e08deaaeeac0a56039b7d1a 159 Gene3D G3DSA:1.10.10.1590 5 74 2.2E-15 T 12-10-2018 NPD12_2002 aa5f5cdf8e08deaaeeac0a56039b7d1a 159 Gene3D G3DSA:3.40.30.10 75 157 1.3E-30 T 12-10-2018 NPD12_3101 7d988728d29f084ea05e599ec5ff0e85 372 Pfam PF01098 Cell cycle protein 20 368 2.0E-98 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_3101 7d988728d29f084ea05e599ec5ff0e85 372 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 16 368 1.6E-116 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_3101 7d988728d29f084ea05e599ec5ff0e85 372 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 10 370 24.901 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_3101 7d988728d29f084ea05e599ec5ff0e85 372 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 325 349 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_3112 82c1c84ea79b9011b2dd9f605be1e8ff 233 SUPERFAMILY SSF110997 68 136 7.59E-5 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 NPD12_2137 fedcc19afb4d3eb9baf3c40892657167 361 Pfam PF03845 Spore germination protein 9 322 5.1E-76 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_2137 fedcc19afb4d3eb9baf3c40892657167 361 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 12 357 3.3E-73 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_2137 fedcc19afb4d3eb9baf3c40892657167 361 Gene3D G3DSA:1.20.1740.10 9 248 5.5E-10 T 12-10-2018 NPD12_2569 9391d3d2fbeb8c73e3c6c27c68e2bb3b 217 SUPERFAMILY SSF109755 2 216 3.98E-76 T 12-10-2018 NPD12_2569 9391d3d2fbeb8c73e3c6c27c68e2bb3b 217 Gene3D G3DSA:1.20.58.220 1 217 2.9E-81 T 12-10-2018 IPR038078 PhoU-like domain superfamily NPD12_2569 9391d3d2fbeb8c73e3c6c27c68e2bb3b 217 PIRSF PIRSF003107 1 217 9.6E-71 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 NPD12_2569 9391d3d2fbeb8c73e3c6c27c68e2bb3b 217 Pfam PF01895 PhoU domain 16 103 3.0E-27 T 12-10-2018 IPR026022 PhoU domain NPD12_2569 9391d3d2fbeb8c73e3c6c27c68e2bb3b 217 Pfam PF01895 PhoU domain 120 204 4.3E-21 T 12-10-2018 IPR026022 PhoU domain NPD12_2569 9391d3d2fbeb8c73e3c6c27c68e2bb3b 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 213 2.5E-73 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 NPD12_2568 778e9d34494782ca747a3afc1b0df106 444 Pfam PF04459 Protein of unknown function (DUF512) 219 427 7.6E-71 T 12-10-2018 IPR007549 Domain of unknown function DUF512 NPD12_2568 778e9d34494782ca747a3afc1b0df106 444 SUPERFAMILY SSF50156 5 91 1.58E-8 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 NPD12_2568 778e9d34494782ca747a3afc1b0df106 444 Gene3D G3DSA:2.30.42.10 4 80 2.4E-5 T 12-10-2018 NPD12_2568 778e9d34494782ca747a3afc1b0df106 444 Gene3D G3DSA:3.20.20.70 118 317 4.5E-7 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2568 778e9d34494782ca747a3afc1b0df106 444 SUPERFAMILY SSF102114 79 228 2.94E-10 T 12-10-2018 NPD12_3304 fb281df01143d72541b0f794fd133774 297 Gene3D G3DSA:3.40.50.11900 206 296 9.8E-7 T 12-10-2018 NPD12_3304 fb281df01143d72541b0f794fd133774 297 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 2 199 1.3E-53 T 12-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 NPD12_3123 2f67b150f6d310da2a212b74ea7ee0c0 269 Gene3D G3DSA:2.60.120.260 11 155 3.2E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_3123 2f67b150f6d310da2a212b74ea7ee0c0 269 SUPERFAMILY SSF49785 28 149 8.51E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_734 42677de4ac67e2bedd04f718132622be 127 SMART SM00304 39 96 4.0E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_734 42677de4ac67e2bedd04f718132622be 127 SUPERFAMILY SSF158472 52 94 6.41E-7 T 12-10-2018 NPD12_734 42677de4ac67e2bedd04f718132622be 127 Gene3D G3DSA:1.20.1480.50 2 102 4.4E-8 T 12-10-2018 NPD12_734 42677de4ac67e2bedd04f718132622be 127 Pfam PF00672 HAMP domain 51 92 3.4E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 NPD12_3111 bacc53c5f339d9d3cf3550470ba5e810 85 Pfam PF14209 Domain of unknown function (DUF4321) 36 83 1.8E-17 T 12-10-2018 IPR025470 Protein of unknown function DUF4321 NPD12_49 04820113aff017f2c744e3eb62c5c652 83 SUPERFAMILY SSF55021 1 79 3.66E-24 T 12-10-2018 NPD12_49 04820113aff017f2c744e3eb62c5c652 83 Gene3D G3DSA:3.30.70.1150 1 83 1.5E-27 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal NPD12_49 04820113aff017f2c744e3eb62c5c652 83 TIGRFAM TIGR03959 hyd_TM1266: putative iron-only hydrogenase system regulator 3 78 1.9E-30 T 12-10-2018 IPR023860 [FeFe]-hydrogenase system regulator TM1266 NPD12_1161 ababb706c7fd5a96e2efb351449f7858 372 Gene3D G3DSA:3.40.50.1100 101 202 4.2E-77 T 12-10-2018 NPD12_1161 ababb706c7fd5a96e2efb351449f7858 372 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 366 9.9E-55 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme NPD12_1161 ababb706c7fd5a96e2efb351449f7858 372 SUPERFAMILY SSF53686 56 371 9.56E-60 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme NPD12_1161 ababb706c7fd5a96e2efb351449f7858 372 Gene3D G3DSA:3.40.50.1100 65 371 4.2E-77 T 12-10-2018 NPD12_2814 f9d2e6b78e356a7456400d9e4ec68999 473 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 420 1.2E-50 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2814 f9d2e6b78e356a7456400d9e4ec68999 473 PIRSF PIRSF006603 2 457 3.7E-86 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2814 f9d2e6b78e356a7456400d9e4ec68999 473 Pfam PF01554 MatE 23 184 2.5E-25 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2814 f9d2e6b78e356a7456400d9e4ec68999 473 Pfam PF01554 MatE 257 408 5.3E-19 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_1039 d4dab00181a43e7fad98046bec2c1f66 233 SUPERFAMILY SSF51182 4 229 7.27E-67 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_1039 d4dab00181a43e7fad98046bec2c1f66 233 Pfam PF02678 Pirin 15 118 2.6E-31 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 NPD12_1039 d4dab00181a43e7fad98046bec2c1f66 233 Gene3D G3DSA:2.60.120.10 8 229 3.9E-78 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1039 d4dab00181a43e7fad98046bec2c1f66 233 Gene3D G3DSA:2.60.120.10 11 134 3.9E-78 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_1039 d4dab00181a43e7fad98046bec2c1f66 233 PIRSF PIRSF006232 1 231 4.7E-54 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 NPD12_377 51e1e7a1dfde33f214fb4b439e596a91 367 SUPERFAMILY SSF53822 41 290 6.06E-10 T 12-10-2018 IPR028082 Periplasmic binding protein-like I NPD12_377 51e1e7a1dfde33f214fb4b439e596a91 367 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 44 352 7.3E-65 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 NPD12_377 51e1e7a1dfde33f214fb4b439e596a91 367 Gene3D G3DSA:3.40.50.2300 43 315 5.2E-105 T 12-10-2018 NPD12_377 51e1e7a1dfde33f214fb4b439e596a91 367 Gene3D G3DSA:3.40.50.2300 143 349 5.2E-105 T 12-10-2018 NPD12_3508 ea9fdf913ca00dff55b07fe8621144a6 116 SUPERFAMILY SSF56276 3 114 1.96E-34 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 NPD12_3508 ea9fdf913ca00dff55b07fe8621144a6 116 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 1.4E-36 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 NPD12_3508 ea9fdf913ca00dff55b07fe8621144a6 116 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 3.1E-42 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 NPD12_3508 ea9fdf913ca00dff55b07fe8621144a6 116 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 114 25.226 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 NPD12_3508 ea9fdf913ca00dff55b07fe8621144a6 116 Gene3D G3DSA:3.30.360.110 1 62 3.0E-19 T 12-10-2018 NPD12_3508 ea9fdf913ca00dff55b07fe8621144a6 116 Gene3D G3DSA:3.30.160.750 63 116 1.0E-19 T 12-10-2018 NPD12_2184 c57d17cfaffc6e2785e4284f263e7c08 238 Gene3D G3DSA:3.40.50.1820 9 233 2.1E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2184 c57d17cfaffc6e2785e4284f263e7c08 238 SUPERFAMILY SSF53474 10 230 4.45E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2270 a210b99b50e22572028cafb4684c1560 891 Gene3D G3DSA:2.60.40.1120 297 399 2.2E-11 T 12-10-2018 NPD12_2270 a210b99b50e22572028cafb4684c1560 891 Pfam PF00746 LPXTG cell wall anchor motif 856 889 2.6E-5 T 12-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor NPD12_2270 a210b99b50e22572028cafb4684c1560 891 Gene3D G3DSA:3.20.20.140 492 710 8.5E-24 T 12-10-2018 NPD12_2270 a210b99b50e22572028cafb4684c1560 891 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 856 890 5.2E-5 T 12-10-2018 NPD12_2270 a210b99b50e22572028cafb4684c1560 891 SUPERFAMILY SSF89550 493 711 3.14E-28 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_2270 a210b99b50e22572028cafb4684c1560 891 SUPERFAMILY SSF49464 296 411 6.28E-12 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily NPD12_2270 a210b99b50e22572028cafb4684c1560 891 Pfam PF13620 Carboxypeptidase regulatory-like domain 297 388 1.2E-8 T 12-10-2018 NPD12_2142 8b5f0c41b1bdc0a270c4c0af5f630ac3 142 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 15 142 9.7E-20 T 12-10-2018 IPR010181 CGCAxxGCC motif NPD12_2142 8b5f0c41b1bdc0a270c4c0af5f630ac3 142 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 14 140 1.7E-28 T 12-10-2018 IPR010181 CGCAxxGCC motif NPD12_1965 0b80af3b5a381276c2c16f06e6a06e68 426 Pfam PF03313 Serine dehydratase alpha chain 171 419 2.4E-49 T 12-10-2018 IPR005130 Serine dehydratase-like, alpha subunit NPD12_1965 0b80af3b5a381276c2c16f06e6a06e68 426 PIRSF PIRSF006054 1 425 5.1E-122 T 12-10-2018 IPR021144 Uncharacterised protein family UPF0597 NPD12_1965 0b80af3b5a381276c2c16f06e6a06e68 426 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 2 423 33.484 T 12-10-2018 IPR021144 Uncharacterised protein family UPF0597 NPD12_1336 abb4308690828e99e3defb31379356c1 109 PIRSF PIRSF006639 1 108 2.4E-29 T 12-10-2018 IPR011379 NTP Pyrophosphohydrolase MazG-related, GP37 NPD12_1336 abb4308690828e99e3defb31379356c1 109 SUPERFAMILY SSF101386 1 99 3.27E-21 T 12-10-2018 NPD12_1336 abb4308690828e99e3defb31379356c1 109 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 31 99 3.5E-14 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core NPD12_1336 abb4308690828e99e3defb31379356c1 109 Gene3D G3DSA:1.10.287.1080 2 108 1.6E-15 T 12-10-2018 NPD12_481 81cf1532201ceff59f1f4fb7e3e65bb6 190 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 38.762 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 NPD12_481 81cf1532201ceff59f1f4fb7e3e65bb6 190 SUPERFAMILY SSF53271 2 186 1.01E-43 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_481 81cf1532201ceff59f1f4fb7e3e65bb6 190 Gene3D G3DSA:3.40.50.2020 3 188 2.6E-53 T 12-10-2018 NPD12_481 81cf1532201ceff59f1f4fb7e3e65bb6 190 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 2 189 2.8E-75 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 NPD12_481 81cf1532201ceff59f1f4fb7e3e65bb6 190 Pfam PF00156 Phosphoribosyl transferase domain 34 157 5.7E-10 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_2340 0f05132014214d09859516d3bc448cff 357 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 NPD12_2340 0f05132014214d09859516d3bc448cff 357 SUPERFAMILY SSF51735 147 315 1.62E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2340 0f05132014214d09859516d3bc448cff 357 SMART SM00829 10 350 7.6E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 NPD12_2340 0f05132014214d09859516d3bc448cff 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 143 3.7E-35 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 NPD12_2340 0f05132014214d09859516d3bc448cff 357 Gene3D G3DSA:3.40.50.720 160 296 5.1E-105 T 12-10-2018 NPD12_2340 0f05132014214d09859516d3bc448cff 357 Pfam PF00107 Zinc-binding dehydrogenase 183 309 3.9E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 NPD12_2340 0f05132014214d09859516d3bc448cff 357 SUPERFAMILY SSF50129 1 182 1.98E-55 T 12-10-2018 IPR011032 GroES-like superfamily NPD12_2340 0f05132014214d09859516d3bc448cff 357 Gene3D G3DSA:3.90.180.10 9 331 5.1E-105 T 12-10-2018 NPD12_3221 01f7f53ef27f7aac3efeacb1da0aebf1 1257 SUPERFAMILY SSF117281 191 528 9.94E-5 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 NPD12_3221 01f7f53ef27f7aac3efeacb1da0aebf1 1257 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 1111 1239 8.8E-13 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 NPD12_3221 01f7f53ef27f7aac3efeacb1da0aebf1 1257 SMART SM00047 1098 1252 3.0E-38 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 NPD12_3221 01f7f53ef27f7aac3efeacb1da0aebf1 1257 Gene3D G3DSA:1.10.530.10 1107 1245 3.3E-8 T 12-10-2018 NPD12_1887 6c82f4350d5e7de4537856c9d68d70cb 362 Gene3D G3DSA:2.60.40.1080 194 279 1.2E-26 T 12-10-2018 NPD12_1887 6c82f4350d5e7de4537856c9d68d70cb 362 SUPERFAMILY SSF49373 194 277 8.63E-22 T 12-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments NPD12_1887 6c82f4350d5e7de4537856c9d68d70cb 362 SMART SM00635 197 274 2.7E-15 T 12-10-2018 IPR003343 Bacterial Ig-like, group 2 NPD12_1887 6c82f4350d5e7de4537856c9d68d70cb 362 Pfam PF02368 Bacterial Ig-like domain (group 2) 199 274 7.8E-16 T 12-10-2018 IPR003343 Bacterial Ig-like, group 2 NPD12_1887 6c82f4350d5e7de4537856c9d68d70cb 362 Gene3D G3DSA:2.60.120.260 65 192 3.2E-5 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily NPD12_94 dcb3756f4a92319711943278f05979ea 61 Pfam PF08984 Domain of unknown function (DUF1858) 3 56 1.2E-24 T 12-10-2018 IPR015077 Domain of unknown function DUF1858 NPD12_94 dcb3756f4a92319711943278f05979ea 61 Gene3D G3DSA:1.10.3910.10 1 61 9.5E-29 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily NPD12_94 dcb3756f4a92319711943278f05979ea 61 SUPERFAMILY SSF140683 1 61 2.22E-20 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily NPD12_94 dcb3756f4a92319711943278f05979ea 61 TIGRFAM TIGR03980 prismane_assoc: hybrid cluster protein-associated redox disulfide domain 3 60 7.8E-30 T 12-10-2018 IPR023883 Conserved hypothetical protein CHP03980, redox-disulphide NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 Gene3D G3DSA:3.40.50.720 6 258 1.1E-93 T 12-10-2018 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 119 2.8E-29 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 282 32.762 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 SUPERFAMILY SSF53223 1 119 9.4E-27 T 12-10-2018 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 32 54 3.1E-56 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 108 129 3.1E-56 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 3.1E-56 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 73 100 3.1E-56 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 3.1E-56 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.1E-56 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 3.1E-56 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 SUPERFAMILY SSF51735 121 281 1.5E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 122 281 5.3E-61 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 NPD12_1359 27a33962a84d25ea7a9d43b99ba76e38 282 Gene3D G3DSA:3.40.50.10860 7 275 1.1E-93 T 12-10-2018 NPD12_3567 e93a85e0ff950f9995b303346b166412 167 Gene3D G3DSA:2.60.40.200 7 164 1.3E-39 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 NPD12_3567 e93a85e0ff950f9995b303346b166412 167 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 22 156 7.1E-36 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 NPD12_3567 e93a85e0ff950f9995b303346b166412 167 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 145 156 - T 12-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 NPD12_3567 e93a85e0ff950f9995b303346b166412 167 SUPERFAMILY SSF49329 21 157 2.09E-41 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 NPD12_654 8ea64f6586634813012542136c170826 318 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 139 314 1.3E-59 T 12-10-2018 IPR020051 SagB-type dehydrogenase domain NPD12_654 8ea64f6586634813012542136c170826 318 Gene3D G3DSA:3.40.109.10 97 314 5.9E-48 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_654 8ea64f6586634813012542136c170826 318 Pfam PF00881 Nitroreductase family 124 314 5.0E-26 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_654 8ea64f6586634813012542136c170826 318 SUPERFAMILY SSF55469 121 315 1.35E-21 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_1839 29722a50e72791f529f0c6b96dc36faf 151 Pfam PF09537 Domain of unknown function (DUF2383) 9 95 6.7E-8 T 12-10-2018 IPR019052 Domain of unknown function DUF2383 NPD12_1839 29722a50e72791f529f0c6b96dc36faf 151 Gene3D G3DSA:1.20.1260.10 6 148 8.5E-33 T 12-10-2018 IPR012347 Ferritin-like NPD12_2321 b306e7956c4d964fa4a8a698861198b2 423 Gene3D G3DSA:3.40.50.11890 73 201 4.5E-5 T 12-10-2018 NPD12_2321 b306e7956c4d964fa4a8a698861198b2 423 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 75 416 3.8E-50 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_2321 b306e7956c4d964fa4a8a698861198b2 423 Gene3D G3DSA:3.40.50.11900 302 421 6.7E-15 T 12-10-2018 NPD12_2321 b306e7956c4d964fa4a8a698861198b2 423 Gene3D G3DSA:1.20.1270.370 202 265 4.5E-5 T 12-10-2018 NPD12_1210 3bc4b070c84c98f4096343bf97fdaa2d 73 Pfam PF06695 Putative small multi-drug export protein 2 59 4.1E-23 T 12-10-2018 IPR009577 Putative small multi-drug export NPD12_401 b692b2d26c87b6b03e3ecf3e0984fd1d 243 Gene3D G3DSA:1.10.10.60 135 241 2.7E-12 T 12-10-2018 NPD12_401 b692b2d26c87b6b03e3ecf3e0984fd1d 243 Pfam PF12833 Helix-turn-helix domain 163 237 8.2E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_401 b692b2d26c87b6b03e3ecf3e0984fd1d 243 SMART SM00342 156 238 4.8E-9 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_1605 1696eb439a75213cf76d5d81ce275f9c 304 SUPERFAMILY SSF53807 37 300 2.0E-64 T 12-10-2018 NPD12_1605 1696eb439a75213cf76d5d81ce275f9c 304 Gene3D G3DSA:3.40.50.1980 172 300 1.8E-30 T 12-10-2018 NPD12_1605 1696eb439a75213cf76d5d81ce275f9c 304 Pfam PF01497 Periplasmic binding protein 56 277 2.2E-33 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain NPD12_1605 1696eb439a75213cf76d5d81ce275f9c 304 Gene3D G3DSA:3.40.50.1980 40 171 1.2E-35 T 12-10-2018 NPD12_1308 39f8b25ffb4d5c2fc7fab4f535994e18 198 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 36 192 2.0E-29 T 12-10-2018 IPR005642 Lysine exporter LysO NPD12_1308 39f8b25ffb4d5c2fc7fab4f535994e18 198 Pfam PF03956 Lysine exporter LysO 7 195 1.0E-62 T 12-10-2018 IPR005642 Lysine exporter LysO NPD12_3002 89819b866fa675137c093ee9d18d863c 58 Gene3D G3DSA:1.20.5.1150 16 54 2.7E-19 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 23.418 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 38 8.0E-6 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.5E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.5E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.5E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.5E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 Pfam PF01165 Ribosomal protein S21 4 57 3.3E-24 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 58 2.2E-23 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3002 89819b866fa675137c093ee9d18d863c 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 12-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_446 400969c7a5a6d33869dd41d62a379af3 169 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 26 144 3.9E-47 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_446 400969c7a5a6d33869dd41d62a379af3 169 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 87 99 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_446 400969c7a5a6d33869dd41d62a379af3 169 Gene3D G3DSA:2.70.70.10 12 169 3.0E-57 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_446 400969c7a5a6d33869dd41d62a379af3 169 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 25 145 1.8E-50 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 NPD12_446 400969c7a5a6d33869dd41d62a379af3 169 SUPERFAMILY SSF51261 22 166 1.57E-53 T 12-10-2018 IPR011055 Duplicated hybrid motif NPD12_2630 857345f338d15be09876bd367f7309e1 512 SUPERFAMILY SSF56801 19 466 3.27E-39 T 12-10-2018 NPD12_2630 857345f338d15be09876bd367f7309e1 512 Gene3D G3DSA:3.40.50.12780 1 404 6.5E-32 T 12-10-2018 NPD12_2630 857345f338d15be09876bd367f7309e1 512 Pfam PF00501 AMP-binding enzyme 139 406 2.1E-29 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 NPD12_397 2f2aecd09a8a8a19eae2edef0cc22783 302 SUPERFAMILY SSF53067 3 296 9.27E-44 T 12-10-2018 NPD12_397 2f2aecd09a8a8a19eae2edef0cc22783 302 Gene3D G3DSA:3.30.420.40 103 295 3.5E-35 T 12-10-2018 NPD12_397 2f2aecd09a8a8a19eae2edef0cc22783 302 Gene3D G3DSA:3.30.420.40 1 101 1.4E-15 T 12-10-2018 NPD12_397 2f2aecd09a8a8a19eae2edef0cc22783 302 Pfam PF00480 ROK family 4 290 1.4E-34 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 NPD12_52 2b5fc89c1788f20e57d6172f79f2eb89 399 Pfam PF01926 50S ribosome-binding GTPase 12 126 8.6E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 NPD12_52 2b5fc89c1788f20e57d6172f79f2eb89 399 Gene3D G3DSA:3.40.50.11410 286 394 2.3E-40 T 12-10-2018 NPD12_52 2b5fc89c1788f20e57d6172f79f2eb89 399 Gene3D G3DSA:3.40.50.300 2 176 1.4E-33 T 12-10-2018 NPD12_52 2b5fc89c1788f20e57d6172f79f2eb89 399 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 3 390 9.3E-163 T 12-10-2018 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF NPD12_52 2b5fc89c1788f20e57d6172f79f2eb89 399 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 139 2.2E-18 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 NPD12_52 2b5fc89c1788f20e57d6172f79f2eb89 399 SUPERFAMILY SSF52540 7 167 9.85E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_52 2b5fc89c1788f20e57d6172f79f2eb89 399 Gene3D G3DSA:3.40.50.11420 178 285 5.8E-42 T 12-10-2018 NPD12_843 e0bd1d00dc635485ee6dcacf67e8d004 328 SMART SM00849 22 231 5.5E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_843 e0bd1d00dc635485ee6dcacf67e8d004 328 SUPERFAMILY SSF56281 21 324 1.31E-51 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_843 e0bd1d00dc635485ee6dcacf67e8d004 328 Gene3D G3DSA:3.60.15.10 1 258 9.4E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_843 e0bd1d00dc635485ee6dcacf67e8d004 328 Pfam PF00753 Metallo-beta-lactamase superfamily 24 83 2.1E-8 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_3278 3a1d483a9e09223e52529e0fba7281a7 251 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3278 3a1d483a9e09223e52529e0fba7281a7 251 SMART SM00382 38 226 3.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3278 3a1d483a9e09223e52529e0fba7281a7 251 Gene3D G3DSA:3.40.50.300 2 232 9.7E-63 T 12-10-2018 NPD12_3278 3a1d483a9e09223e52529e0fba7281a7 251 SUPERFAMILY SSF52540 4 235 2.86E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3278 3a1d483a9e09223e52529e0fba7281a7 251 Pfam PF00005 ABC transporter 30 177 8.6E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_698 c09fe95f04ebc9987ffc4a1716765dd4 836 Pfam PF02687 FtsX-like permease family 735 818 6.8E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_698 c09fe95f04ebc9987ffc4a1716765dd4 836 Pfam PF02687 FtsX-like permease family 291 384 4.7E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Gene3D G3DSA:2.60.40.740 360 473 1.7E-5 T 12-10-2018 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Pfam PF01345 Domain of unknown function DUF11 909 995 7.4E-13 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Pfam PF01345 Domain of unknown function DUF11 746 838 6.4E-12 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Pfam PF01345 Domain of unknown function DUF11 623 714 5.4E-10 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Pfam PF01345 Domain of unknown function DUF11 497 579 5.7E-11 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Pfam PF01345 Domain of unknown function DUF11 363 458 2.9E-11 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Pfam PF17210 SdrD B-like domain 3 67 5.2E-9 T 12-10-2018 IPR033764 SD-repeat containing protein, B domain NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 911 951 2.4E-12 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 363 415 7.5E-15 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 623 668 6.4E-9 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 748 795 5.4E-11 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 497 544 8.5E-12 T 12-10-2018 IPR001434 Domain of unknown function DUF11 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 SUPERFAMILY SSF117074 2 76 1.44E-12 T 12-10-2018 NPD12_1249 207bc62285cdd941e485ebc2df0fe696 1053 Gene3D G3DSA:2.60.40.10 1 121 1.8E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_2703 b534d1dc8ecbdd93df50f5719ff9da30 69 Pfam PF06289 Flagellar protein (FlbD) 1 58 1.8E-25 T 12-10-2018 IPR009384 Swarming motility protein SwrD-like NPD12_2361 490e6e120dd33b4e107bf77064a99520 239 SUPERFAMILY SSF52540 2 230 2.04E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2361 490e6e120dd33b4e107bf77064a99520 239 Pfam PF00005 ABC transporter 19 162 5.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2361 490e6e120dd33b4e107bf77064a99520 239 SMART SM00382 27 213 6.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2361 490e6e120dd33b4e107bf77064a99520 239 Gene3D G3DSA:3.40.50.300 1 239 1.1E-69 T 12-10-2018 NPD12_177 7c4652438cd9a92f0e54ce60c58b428d 234 SUPERFAMILY SSF69572 5 232 1.31E-60 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 NPD12_177 7c4652438cd9a92f0e54ce60c58b428d 234 Pfam PF00899 ThiF family 10 170 5.0E-41 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 NPD12_177 7c4652438cd9a92f0e54ce60c58b428d 234 Gene3D G3DSA:3.40.50.720 1 234 1.4E-77 T 12-10-2018 NPD12_727 96311591cb64bc3827f1fcfff555cdf7 227 Gene3D G3DSA:1.10.1760.20 53 217 3.9E-47 T 12-10-2018 NPD12_727 96311591cb64bc3827f1fcfff555cdf7 227 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 55 211 6.0E-45 T 12-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 NPD12_727 96311591cb64bc3827f1fcfff555cdf7 227 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 57 211 4.6E-47 T 12-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 NPD12_3256 c4e2af6dde2d5e1f9242aedb0d244d84 296 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 292 38.351 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 NPD12_3256 c4e2af6dde2d5e1f9242aedb0d244d84 296 SUPERFAMILY SSF118352 234 291 9.68E-18 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 NPD12_3256 c4e2af6dde2d5e1f9242aedb0d244d84 296 Gene3D G3DSA:3.90.1280.10 238 295 1.4E-19 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 NPD12_3256 c4e2af6dde2d5e1f9242aedb0d244d84 296 PIRSF PIRSF005261 1 292 2.3E-84 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 NPD12_3256 c4e2af6dde2d5e1f9242aedb0d244d84 296 Pfam PF01430 Hsp33 protein 3 281 6.7E-84 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 NPD12_3256 c4e2af6dde2d5e1f9242aedb0d244d84 296 Gene3D G3DSA:3.55.30.10 2 236 8.3E-84 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 NPD12_3256 c4e2af6dde2d5e1f9242aedb0d244d84 296 SUPERFAMILY SSF64397 2 242 6.02E-73 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 NPD12_1430 2f0d95365096439516ffcc705674093d 195 SUPERFAMILY SSF46689 9 83 2.62E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1430 2f0d95365096439516ffcc705674093d 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 63 4.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_1430 2f0d95365096439516ffcc705674093d 195 Gene3D G3DSA:1.10.357.10 9 193 7.5E-17 T 12-10-2018 NPD12_1169 82cfdaf629884d4bbaedfd71289facaf 197 PIRSF PIRSF022704 1 197 7.6E-67 T 12-10-2018 IPR015987 Uncharacterised conserved protein UCP022704 NPD12_1169 82cfdaf629884d4bbaedfd71289facaf 197 Pfam PF07081 Protein of unknown function (DUF1349) 11 190 2.4E-67 T 12-10-2018 IPR009784 Protein of unknown function DUF1349 NPD12_1169 82cfdaf629884d4bbaedfd71289facaf 197 Gene3D G3DSA:2.60.120.200 5 196 3.0E-55 T 12-10-2018 NPD12_1169 82cfdaf629884d4bbaedfd71289facaf 197 SUPERFAMILY SSF49899 11 190 1.07E-41 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily NPD12_2154 ce362b9d4fdb8e68eb8481a5468c13f3 307 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 304 6.0E-95 T 12-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 NPD12_2154 ce362b9d4fdb8e68eb8481a5468c13f3 307 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 304 1.0E-93 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 NPD12_2154 ce362b9d4fdb8e68eb8481a5468c13f3 307 Pfam PF00294 pfkB family carbohydrate kinase 11 288 4.4E-47 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB NPD12_2154 ce362b9d4fdb8e68eb8481a5468c13f3 307 PIRSF PIRSF000535 1 306 6.7E-73 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 NPD12_2154 ce362b9d4fdb8e68eb8481a5468c13f3 307 SUPERFAMILY SSF53613 1 285 1.56E-62 T 12-10-2018 IPR029056 Ribokinase-like NPD12_2154 ce362b9d4fdb8e68eb8481a5468c13f3 307 Gene3D G3DSA:3.40.1190.20 1 307 1.0E-82 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1838 3f7c2043c186f1b5f3ddebccd84b9f47 273 SMART SM00954 67 209 5.8E-29 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 NPD12_1838 3f7c2043c186f1b5f3ddebccd84b9f47 273 Pfam PF04607 Region found in RelA / SpoT proteins 67 206 8.6E-30 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 NPD12_1838 3f7c2043c186f1b5f3ddebccd84b9f47 273 Gene3D G3DSA:3.30.460.10 18 190 9.5E-17 T 12-10-2018 NPD12_1838 3f7c2043c186f1b5f3ddebccd84b9f47 273 SUPERFAMILY SSF81301 25 234 3.92E-33 T 12-10-2018 NPD12_2139 01eb1c06eca4cf2ceb102126af962d3e 362 Pfam PF03845 Spore germination protein 7 320 2.9E-69 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_2139 01eb1c06eca4cf2ceb102126af962d3e 362 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 356 1.7E-69 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_476 504fae35fdeee07a5e3257e37a2d4551 337 Pfam PF01032 FecCD transport family 22 335 8.5E-88 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_476 504fae35fdeee07a5e3257e37a2d4551 337 Gene3D G3DSA:1.10.3470.10 9 337 5.1E-91 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_476 504fae35fdeee07a5e3257e37a2d4551 337 SUPERFAMILY SSF81345 9 335 2.48E-78 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1577 9c83b0e314e612a5fcbf5697366ffdfe 124 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 18 118 2.9E-16 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV NPD12_378 1cef790a4bde5448beb86c5011f12515 504 Pfam PF00005 ABC transporter 15 163 7.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_378 1cef790a4bde5448beb86c5011f12515 504 Pfam PF00005 ABC transporter 267 423 2.6E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_378 1cef790a4bde5448beb86c5011f12515 504 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_378 1cef790a4bde5448beb86c5011f12515 504 SUPERFAMILY SSF52540 250 483 1.38E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_378 1cef790a4bde5448beb86c5011f12515 504 SUPERFAMILY SSF52540 2 220 4.56E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_378 1cef790a4bde5448beb86c5011f12515 504 SMART SM00382 23 211 4.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_378 1cef790a4bde5448beb86c5011f12515 504 Gene3D G3DSA:3.40.50.300 233 491 4.7E-41 T 12-10-2018 NPD12_378 1cef790a4bde5448beb86c5011f12515 504 Gene3D G3DSA:3.40.50.300 1 232 5.3E-55 T 12-10-2018 NPD12_220 3abaa3ee342c4310e3cb143d1f7e6b95 367 SUPERFAMILY SSF54001 253 359 9.57E-44 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_220 3abaa3ee342c4310e3cb143d1f7e6b95 367 Pfam PF00877 NlpC/P60 family 270 358 6.4E-29 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain NPD12_220 3abaa3ee342c4310e3cb143d1f7e6b95 367 SUPERFAMILY SSF57997 30 92 7.63E-7 T 12-10-2018 NPD12_220 3abaa3ee342c4310e3cb143d1f7e6b95 367 Gene3D G3DSA:3.90.1720.10 167 366 2.8E-55 T 12-10-2018 NPD12_1089 73aa137896cf3c4ac18a2cd5e5a66014 341 SUPERFAMILY SSF56752 5 337 2.22E-105 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 NPD12_1089 73aa137896cf3c4ac18a2cd5e5a66014 341 ProSitePatterns PS00770 Aminotransferases class-IV signature. 221 250 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 NPD12_1089 73aa137896cf3c4ac18a2cd5e5a66014 341 Gene3D G3DSA:3.20.10.10 162 341 3.1E-56 T 12-10-2018 NPD12_1089 73aa137896cf3c4ac18a2cd5e5a66014 341 PIRSF PIRSF006468 1 341 4.9E-123 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 NPD12_1089 73aa137896cf3c4ac18a2cd5e5a66014 341 Pfam PF01063 Amino-transferase class IV 57 294 1.0E-36 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 NPD12_1089 73aa137896cf3c4ac18a2cd5e5a66014 341 Gene3D G3DSA:3.30.470.10 1 161 1.0E-59 T 12-10-2018 NPD12_1089 73aa137896cf3c4ac18a2cd5e5a66014 341 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 32 340 2.5E-140 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 NPD12_3059 7b197d20c2e467b27f752751215c419d 397 Gene3D G3DSA:3.40.50.10810 2 165 5.1E-17 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily NPD12_3059 7b197d20c2e467b27f752751215c419d 397 SUPERFAMILY SSF52540 59 392 5.89E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3059 7b197d20c2e467b27f752751215c419d 397 Pfam PF00271 Helicase conserved C-terminal domain 245 349 2.9E-5 T 12-10-2018 IPR001650 Helicase, C-terminal NPD12_3059 7b197d20c2e467b27f752751215c419d 397 Gene3D G3DSA:3.40.50.300 177 396 1.2E-25 T 12-10-2018 NPD12_3059 7b197d20c2e467b27f752751215c419d 397 Pfam PF00176 SNF2 family N-terminal domain 4 208 2.1E-16 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 NPD12_3420 f1e7d28c1bfdb3b34e456ff0fa7f6148 412 Gene3D G3DSA:3.40.50.10540 9 400 1.8E-96 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily NPD12_3420 f1e7d28c1bfdb3b34e456ff0fa7f6148 412 Pfam PF02515 CoA-transferase family III 9 382 3.2E-84 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 NPD12_3420 f1e7d28c1bfdb3b34e456ff0fa7f6148 412 SUPERFAMILY SSF89796 3 406 8.5E-96 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily NPD12_3420 f1e7d28c1bfdb3b34e456ff0fa7f6148 412 Gene3D G3DSA:3.30.1540.10 236 335 1.8E-96 T 12-10-2018 NPD12_3283 b5824848a7549ba49dd79180f8979fd4 267 Gene3D G3DSA:1.10.3720.10 67 264 8.5E-22 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3283 b5824848a7549ba49dd79180f8979fd4 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 265 7.2E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_3283 b5824848a7549ba49dd79180f8979fd4 267 SUPERFAMILY SSF161098 68 254 2.09E-29 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1342 c7bff2dffbf83714a5e483c000a76ae6 562 Gene3D G3DSA:1.10.3720.10 22 282 1.3E-48 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1342 c7bff2dffbf83714a5e483c000a76ae6 562 Gene3D G3DSA:1.10.3720.10 298 554 2.0E-38 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1342 c7bff2dffbf83714a5e483c000a76ae6 562 SUPERFAMILY SSF161098 301 553 2.62E-38 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1342 c7bff2dffbf83714a5e483c000a76ae6 562 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 271 7.6E-8 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1342 c7bff2dffbf83714a5e483c000a76ae6 562 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 367 542 5.4E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1342 c7bff2dffbf83714a5e483c000a76ae6 562 SUPERFAMILY SSF161098 21 272 4.02E-44 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2909 02294430057d9a78b28927c83913de61 83 SUPERFAMILY SSF47336 5 81 2.59E-7 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2909 02294430057d9a78b28927c83913de61 83 TIGRFAM TIGR04069 ocin_ACP_rel: peptide maturation system acyl carrier-related protein 3 79 1.8E-33 T 12-10-2018 IPR023972 Conserved hypothetical protein CHP04069, acyl carrier-related NPD12_2909 02294430057d9a78b28927c83913de61 83 Gene3D G3DSA:1.10.1200.10 2 83 2.7E-10 T 12-10-2018 IPR036736 ACP-like superfamily NPD12_2307 fad889517e5aa2ad81c6712a60b18550 343 SUPERFAMILY SSF53474 70 339 3.74E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2307 fad889517e5aa2ad81c6712a60b18550 343 Gene3D G3DSA:3.40.50.1820 34 340 2.7E-86 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2307 fad889517e5aa2ad81c6712a60b18550 343 Pfam PF07859 alpha/beta hydrolase fold 110 317 3.2E-69 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 NPD12_1305 28c0d500a1c71eb6a7debfd27df2ab71 183 Gene3D G3DSA:3.40.630.30 6 182 5.0E-46 T 12-10-2018 NPD12_1305 28c0d500a1c71eb6a7debfd27df2ab71 183 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 1.4E-21 T 12-10-2018 IPR000182 GNAT domain NPD12_1305 28c0d500a1c71eb6a7debfd27df2ab71 183 SUPERFAMILY SSF55729 6 176 3.77E-42 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2440 e1355156ef2ae64116c8b8ab5dbf54a7 180 SUPERFAMILY SSF46934 5 46 1.53E-5 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 NPD12_2440 e1355156ef2ae64116c8b8ab5dbf54a7 180 Pfam PF14242 Domain of unknown function (DUF4342) 85 139 4.5E-6 T 12-10-2018 IPR025642 Domain of unknown function DUF4342 NPD12_303 8d995f5530dfdf16d216d3a41d4d182d 385 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 367 5.9E-121 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 NPD12_303 8d995f5530dfdf16d216d3a41d4d182d 385 SUPERFAMILY SSF53756 3 375 2.46E-134 T 12-10-2018 NPD12_303 8d995f5530dfdf16d216d3a41d4d182d 385 Gene3D G3DSA:3.40.50.2000 7 365 2.1E-145 T 12-10-2018 NPD12_303 8d995f5530dfdf16d216d3a41d4d182d 385 Gene3D G3DSA:3.40.50.2000 192 354 2.1E-145 T 12-10-2018 NPD12_303 8d995f5530dfdf16d216d3a41d4d182d 385 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 370 6.7E-159 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 NPD12_2789 0ae9202428295daf8fcfc419a0cf4c58 277 Gene3D G3DSA:3.30.470.10 3 106 2.2E-14 T 12-10-2018 NPD12_2789 0ae9202428295daf8fcfc419a0cf4c58 277 ProSitePatterns PS00770 Aminotransferases class-IV signature. 169 197 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 NPD12_2789 0ae9202428295daf8fcfc419a0cf4c58 277 Gene3D G3DSA:3.20.10.10 113 270 1.4E-32 T 12-10-2018 NPD12_2789 0ae9202428295daf8fcfc419a0cf4c58 277 Pfam PF01063 Amino-transferase class IV 31 242 6.6E-51 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 NPD12_2789 0ae9202428295daf8fcfc419a0cf4c58 277 SUPERFAMILY SSF56752 27 272 9.29E-46 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 1.1E-46 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 328 1.2E-57 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 295 318 2.4E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 2.4E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 2.4E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 2.4E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 3.9E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 3.9E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 3.9E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 3.9E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 309 320 3.9E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 Gene3D G3DSA:3.40.50.1370 4 327 2.6E-142 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 SUPERFAMILY SSF53671 1 332 9.17E-103 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 6 331 81.909 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 Gene3D G3DSA:3.40.50.1370 150 317 2.6E-142 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 NPD12_2639 a8b62ee684493f0590cfff54927f0860 333 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 7 330 1.6E-128 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 NPD12_34 2356f371dc2a453c8f52cd99a3f55713 632 Pfam PF00120 Glutamine synthetase, catalytic domain 168 450 3.2E-37 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 NPD12_34 2356f371dc2a453c8f52cd99a3f55713 632 SUPERFAMILY SSF55931 127 533 5.4E-60 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 NPD12_34 2356f371dc2a453c8f52cd99a3f55713 632 Gene3D G3DSA:3.30.590.10 131 488 7.4E-56 T 12-10-2018 NPD12_34 2356f371dc2a453c8f52cd99a3f55713 632 SMART SM01230 150 429 1.4E-39 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 NPD12_1149 52088835b69d8fe716e06c14e3ca0338 295 SUPERFAMILY SSF52540 4 218 7.41E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1149 52088835b69d8fe716e06c14e3ca0338 295 SMART SM00382 27 209 2.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1149 52088835b69d8fe716e06c14e3ca0338 295 Pfam PF00005 ABC transporter 21 162 5.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1149 52088835b69d8fe716e06c14e3ca0338 295 Gene3D G3DSA:3.40.50.300 1 236 1.6E-64 T 12-10-2018 NPD12_1149 52088835b69d8fe716e06c14e3ca0338 295 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2884 342fb06a3d42894dfbe78f49226d88dd 189 SUPERFAMILY SSF53448 4 184 5.86E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2884 342fb06a3d42894dfbe78f49226d88dd 189 Gene3D G3DSA:3.90.550.10 1 185 2.1E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2884 342fb06a3d42894dfbe78f49226d88dd 189 Pfam PF12804 MobA-like NTP transferase domain 5 143 1.2E-26 T 12-10-2018 IPR025877 MobA-like NTP transferase NPD12_108 830c7b853e1eb7730c80a23a6b820260 382 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 37 382 2.1E-83 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_108 830c7b853e1eb7730c80a23a6b820260 382 Gene3D G3DSA:1.20.1270.370 21 221 5.5E-40 T 12-10-2018 NPD12_108 830c7b853e1eb7730c80a23a6b820260 382 Gene3D G3DSA:3.40.50.11900 239 382 2.0E-43 T 12-10-2018 NPD12_108 830c7b853e1eb7730c80a23a6b820260 382 Gene3D G3DSA:3.40.50.11890 30 156 5.5E-40 T 12-10-2018 NPD12_1505 ebced48c27f694407647384d01e666cf 135 SUPERFAMILY SSF160719 39 124 6.8E-10 T 12-10-2018 NPD12_1505 ebced48c27f694407647384d01e666cf 135 Pfam PF10934 Protein of unknown function (DUF2634) 27 122 2.6E-32 T 12-10-2018 IPR020288 Protein of unknown function DUF2634 NPD12_1505 ebced48c27f694407647384d01e666cf 135 Gene3D G3DSA:3.10.450.40 21 131 1.9E-5 T 12-10-2018 NPD12_1505 ebced48c27f694407647384d01e666cf 135 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 21 132 8.0E-30 T 12-10-2018 IPR020288 Protein of unknown function DUF2634 NPD12_515 23959cf5ad9439460e2467e88be86eb5 270 Pfam PF01522 Polysaccharide deacetylase 76 187 1.4E-28 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 NPD12_515 23959cf5ad9439460e2467e88be86eb5 270 SUPERFAMILY SSF88713 55 267 1.38E-50 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_515 23959cf5ad9439460e2467e88be86eb5 270 Gene3D G3DSA:3.20.20.370 38 270 9.0E-63 T 12-10-2018 NPD12_2560 15800664c9bed5b51448a5fe45c789ca 72 SUPERFAMILY SSF63562 5 69 3.66E-24 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 NPD12_2560 15800664c9bed5b51448a5fe45c789ca 72 SMART SM01409 12 64 4.4E-15 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 NPD12_2560 15800664c9bed5b51448a5fe45c789ca 72 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 5 62 1.0E-14 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_2560 15800664c9bed5b51448a5fe45c789ca 72 Gene3D G3DSA:3.90.940.10 5 72 7.3E-23 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 NPD12_2560 15800664c9bed5b51448a5fe45c789ca 72 Pfam PF01192 RNA polymerase Rpb6 13 64 6.6E-16 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 NPD12_2560 15800664c9bed5b51448a5fe45c789ca 72 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 5 65 15.571 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 NPD12_2410 684ea2dd5ccee115f8afac0ca8c26d48 100 SUPERFAMILY SSF54909 2 100 4.02E-24 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel NPD12_2410 684ea2dd5ccee115f8afac0ca8c26d48 100 SMART SM00886 2 100 1.1E-37 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel NPD12_2410 684ea2dd5ccee115f8afac0ca8c26d48 100 Pfam PF07876 Stress responsive A/B Barrel Domain 2 100 5.4E-27 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel NPD12_2410 684ea2dd5ccee115f8afac0ca8c26d48 100 Gene3D G3DSA:3.30.70.100 1 100 4.5E-27 T 12-10-2018 NPD12_35 629c6812d721d6c4498e79b8564187b6 182 Pfam PF13563 2'-5' RNA ligase superfamily 14 163 3.5E-10 T 12-10-2018 NPD12_35 629c6812d721d6c4498e79b8564187b6 182 SUPERFAMILY SSF55144 1 179 7.15E-22 T 12-10-2018 IPR009097 Cyclic phosphodiesterase NPD12_35 629c6812d721d6c4498e79b8564187b6 182 Gene3D G3DSA:3.90.1140.10 2 181 3.5E-17 T 12-10-2018 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 Pfam PF06733 DEAD_2 285 406 1.2E-13 T 12-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 SMART SM00491 616 752 3.9E-11 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 Gene3D G3DSA:3.40.50.300 200 553 2.8E-55 T 12-10-2018 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 SMART SM00488 190 437 4.4E-6 T 12-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 SUPERFAMILY SSF52540 160 423 2.16E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 Pfam PF13307 Helicase C-terminal domain 600 765 3.7E-41 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 Gene3D G3DSA:1.10.275.30 399 515 2.8E-55 T 12-10-2018 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 Gene3D G3DSA:3.40.50.300 569 777 7.8E-59 T 12-10-2018 NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 Pfam PF12705 PD-(D/E)XK nuclease superfamily 65 156 2.6E-5 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type NPD12_678 88b0c92a78f69104599a45efc43c2b4d 784 SUPERFAMILY SSF52540 212 745 4.76E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_623 0826a1735b2f4019b09b17917890d4be 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 293 2.1E-48 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 NPD12_2612 333f92cc22cab88f35e7ea4df286e7fd 162 SUPERFAMILY SSF50346 75 135 8.32E-8 T 12-10-2018 IPR011033 PRC-barrel-like superfamily NPD12_2612 333f92cc22cab88f35e7ea4df286e7fd 162 Gene3D G3DSA:2.30.30.240 76 138 5.5E-5 T 12-10-2018 NPD12_2612 333f92cc22cab88f35e7ea4df286e7fd 162 SUPERFAMILY SSF50346 1 67 2.75E-8 T 12-10-2018 IPR011033 PRC-barrel-like superfamily NPD12_2612 333f92cc22cab88f35e7ea4df286e7fd 162 Pfam PF05239 PRC-barrel domain 7 67 4.4E-6 T 12-10-2018 IPR027275 PRC-barrel domain NPD12_2612 333f92cc22cab88f35e7ea4df286e7fd 162 Pfam PF05239 PRC-barrel domain 75 130 7.5E-8 T 12-10-2018 IPR027275 PRC-barrel domain NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 2.0E-128 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 PRINTS PR00175 Sodium/alanine symporter signature 182 200 5.1E-47 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 PRINTS PR00175 Sodium/alanine symporter signature 352 374 5.1E-47 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 PRINTS PR00175 Sodium/alanine symporter signature 93 115 5.1E-47 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 PRINTS PR00175 Sodium/alanine symporter signature 305 323 5.1E-47 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 PRINTS PR00175 Sodium/alanine symporter signature 210 229 5.1E-47 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 PRINTS PR00175 Sodium/alanine symporter signature 411 431 5.1E-47 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 93 108 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1294 2d57b5b2056e1cb99f521e45b1fe8013 465 Pfam PF01235 Sodium:alanine symporter family 57 440 3.6E-119 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2453 6182b3ecf3c8059b14baf174064c0636 194 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 189 1.6E-49 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 NPD12_2453 6182b3ecf3c8059b14baf174064c0636 194 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 NPD12_2453 6182b3ecf3c8059b14baf174064c0636 194 PIRSF PIRSF000847 1 194 7.8E-53 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 NPD12_2453 6182b3ecf3c8059b14baf174064c0636 194 Gene3D G3DSA:1.20.120.1760 3 179 8.3E-11 T 12-10-2018 NPD12_2453 6182b3ecf3c8059b14baf174064c0636 194 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 70 2.7E-17 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 NPD12_553 ba9afb7a9dda60f39b512cfa5b68a4cd 156 Gene3D G3DSA:3.40.50.1000 9 149 7.8E-13 T 12-10-2018 IPR023214 HAD superfamily NPD12_553 ba9afb7a9dda60f39b512cfa5b68a4cd 156 SUPERFAMILY SSF56784 13 117 4.4E-13 T 12-10-2018 IPR036412 HAD-like superfamily NPD12_553 ba9afb7a9dda60f39b512cfa5b68a4cd 156 Pfam PF08282 haloacid dehalogenase-like hydrolase 33 116 5.3E-6 T 12-10-2018 NPD12_728 d00840aa686a83acabfe03efafae86cf 383 Pfam PF02810 SEC-C motif 359 376 1.5E-7 T 12-10-2018 IPR004027 SEC-C motif NPD12_728 d00840aa686a83acabfe03efafae86cf 383 SUPERFAMILY SSF103642 357 377 7.36E-7 T 12-10-2018 NPD12_728 d00840aa686a83acabfe03efafae86cf 383 Gene3D G3DSA:3.10.450.50 321 377 1.0E-7 T 12-10-2018 NPD12_1048 12d471222de485915a3818e756ce4c5e 140 SUPERFAMILY SSF50475 6 112 4.32E-9 T 12-10-2018 NPD12_1048 12d471222de485915a3818e756ce4c5e 140 Gene3D G3DSA:2.30.110.10 4 139 2.8E-42 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_2920 db14c91145383368637830386c302e24 228 Gene3D G3DSA:2.40.30.20 113 216 8.7E-33 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2920 db14c91145383368637830386c302e24 228 Gene3D G3DSA:2.40.30.20 13 100 5.4E-29 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 NPD12_2920 db14c91145383368637830386c302e24 228 Pfam PF00677 Lumazine binding domain 111 195 1.0E-21 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2920 db14c91145383368637830386c302e24 228 Pfam PF00677 Lumazine binding domain 15 98 2.2E-22 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2920 db14c91145383368637830386c302e24 228 SUPERFAMILY SSF63380 105 208 2.21E-29 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel NPD12_2920 db14c91145383368637830386c302e24 228 PIRSF PIRSF000498 13 222 1.6E-74 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_2920 db14c91145383368637830386c302e24 228 SUPERFAMILY SSF63380 13 99 7.74E-25 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel NPD12_2920 db14c91145383368637830386c302e24 228 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 13 211 1.2E-70 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 NPD12_585 73b8a9b869ec75842f1365dce97ba58d 287 Pfam PF00753 Metallo-beta-lactamase superfamily 48 243 1.8E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_585 73b8a9b869ec75842f1365dce97ba58d 287 Gene3D G3DSA:3.60.15.10 37 286 3.8E-80 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_585 73b8a9b869ec75842f1365dce97ba58d 287 SMART SM00849 50 244 2.6E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_585 73b8a9b869ec75842f1365dce97ba58d 287 SUPERFAMILY SSF56281 38 285 6.29E-63 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_313 90f98c08d3ac1d74608af39952aeb56c 235 Gene3D G3DSA:3.30.360.40 163 235 5.7E-6 T 12-10-2018 NPD12_313 90f98c08d3ac1d74608af39952aeb56c 235 SUPERFAMILY SSF143842 32 231 5.23E-38 T 12-10-2018 IPR036209 YwmB-like superfamily NPD12_313 90f98c08d3ac1d74608af39952aeb56c 235 Pfam PF08680 TATA-box binding 60 235 3.0E-8 T 12-10-2018 IPR014794 TATA-box binding NPD12_2634 e89ebdcb26652257702241d879aa943d 170 SUPERFAMILY SSF55729 29 166 8.81E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2634 e89ebdcb26652257702241d879aa943d 170 Gene3D G3DSA:3.40.630.30 11 169 1.7E-19 T 12-10-2018 NPD12_2634 e89ebdcb26652257702241d879aa943d 170 Pfam PF13673 Acetyltransferase (GNAT) domain 56 146 7.5E-10 T 12-10-2018 IPR000182 GNAT domain NPD12_2030 9e5f72aeb4686b48de30db4a8021f068 214 Gene3D G3DSA:3.40.630.40 1 172 7.9E-57 T 12-10-2018 NPD12_2030 9e5f72aeb4686b48de30db4a8021f068 214 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 3 167 4.6E-30 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_2030 9e5f72aeb4686b48de30db4a8021f068 214 SUPERFAMILY SSF53187 1 169 5.65E-43 T 12-10-2018 NPD12_2030 9e5f72aeb4686b48de30db4a8021f068 214 SMART SM00646 65 168 8.4E-17 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 NPD12_2638 2fa7f8553421f868fcfa3a5cd211091d 246 SUPERFAMILY SSF56214 141 210 1.64E-10 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_2638 2fa7f8553421f868fcfa3a5cd211091d 246 SUPERFAMILY SSF56214 46 133 2.35E-11 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_2638 2fa7f8553421f868fcfa3a5cd211091d 246 Gene3D G3DSA:3.90.470.20 53 140 2.5E-26 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_2638 2fa7f8553421f868fcfa3a5cd211091d 246 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 141 215 1.3E-9 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_2638 2fa7f8553421f868fcfa3a5cd211091d 246 Gene3D G3DSA:3.90.470.20 141 229 2.5E-26 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 NPD12_1701 0e4ac6b8905a9c3c242504ab6b15c4f8 212 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 10 209 8.6E-65 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 NPD12_1701 0e4ac6b8905a9c3c242504ab6b15c4f8 212 Pfam PF03006 Haemolysin-III related 8 203 6.9E-39 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 Gene3D G3DSA:3.50.50.60 110 237 9.9E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 SUPERFAMILY SSF51905 1 300 2.01E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 7.4E-19 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 7.4E-19 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 7.4E-19 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 7.4E-19 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 7.4E-19 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.3E-11 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.3E-11 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 1.3E-11 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 1.3E-11 T 12-10-2018 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 290 5.8E-54 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_1594 8b9cb808ff037a85b9d4435503944db5 408 Gene3D G3DSA:3.50.50.60 4 298 9.9E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1966 d867a09a2b64e0d05df4cf3f98e3e799 467 SUPERFAMILY SSF53448 46 325 2.81E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_1966 d867a09a2b64e0d05df4cf3f98e3e799 467 Pfam PF13641 Glycosyltransferase like family 2 47 272 6.7E-29 T 12-10-2018 NPD12_1966 d867a09a2b64e0d05df4cf3f98e3e799 467 Gene3D G3DSA:3.90.550.10 32 269 4.2E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_874 fe33e3e0707fdd9220a067fea0365808 484 SUPERFAMILY SSF53383 25 483 3.55E-109 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_874 fe33e3e0707fdd9220a067fea0365808 484 Gene3D G3DSA:3.40.640.10 85 312 2.7E-61 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_874 fe33e3e0707fdd9220a067fea0365808 484 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 6 484 58.828 T 12-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 NPD12_874 fe33e3e0707fdd9220a067fea0365808 484 Gene3D G3DSA:3.90.1150.10 337 469 2.7E-45 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_874 fe33e3e0707fdd9220a067fea0365808 484 Pfam PF02347 Glycine cleavage system P-protein 33 300 2.5E-13 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 NPD12_1800 990ae49a82bdfb1ff3e22f536d686426 250 Pfam PF06161 Protein of unknown function (DUF975) 140 229 3.5E-27 T 12-10-2018 IPR010380 Protein of unknown function DUF975 NPD12_2319 71070f9d4f55c8b2be19b04851285901 404 Gene3D G3DSA:3.30.1540.10 232 332 7.5E-103 T 12-10-2018 NPD12_2319 71070f9d4f55c8b2be19b04851285901 404 SUPERFAMILY SSF89796 6 403 2.09E-100 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily NPD12_2319 71070f9d4f55c8b2be19b04851285901 404 Pfam PF02515 CoA-transferase family III 8 380 1.8E-92 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 NPD12_2319 71070f9d4f55c8b2be19b04851285901 404 Gene3D G3DSA:3.40.50.10540 8 397 7.5E-103 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily NPD12_2061 aa13f04bc6cef8a4649aeeaa14b8e5c3 307 SUPERFAMILY SSF52540 33 265 2.14E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2061 aa13f04bc6cef8a4649aeeaa14b8e5c3 307 Gene3D G3DSA:3.40.50.300 125 282 4.4E-21 T 12-10-2018 NPD12_2061 aa13f04bc6cef8a4649aeeaa14b8e5c3 307 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 295 8.6E-122 T 12-10-2018 IPR014217 Sporulation stage III, protein AA NPD12_3230 8e2552e645c0688df8666927c167d574 156 Pfam PF04463 Protein of unknown function (DUF523) 2 145 5.8E-44 T 12-10-2018 IPR007553 Domain of unknown function DUF523 NPD12_1441 f9732d3308c70a0be3e80d55699b7267 75 ProSitePatterns PS00195 Glutaredoxin active site. 4 20 - T 12-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 NPD12_1441 f9732d3308c70a0be3e80d55699b7267 75 Gene3D G3DSA:3.40.30.10 1 75 1.6E-24 T 12-10-2018 NPD12_1441 f9732d3308c70a0be3e80d55699b7267 75 TIGRFAM TIGR02196 GlrX_YruB: glutaredoxin-like protein, YruB-family 1 74 5.8E-31 T 12-10-2018 IPR011911 Glutaredoxin-like protein, YruB NPD12_1441 f9732d3308c70a0be3e80d55699b7267 75 SUPERFAMILY SSF52833 1 73 2.23E-19 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_1441 f9732d3308c70a0be3e80d55699b7267 75 Pfam PF00462 Glutaredoxin 2 60 8.9E-18 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 NPD12_2755 20ebce48fdc2c5c74c579298e47b3fd4 221 Gene3D G3DSA:3.40.50.10320 1 221 1.1E-51 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 NPD12_2755 20ebce48fdc2c5c74c579298e47b3fd4 221 SUPERFAMILY SSF102588 1 218 2.22E-38 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 NPD12_2755 20ebce48fdc2c5c74c579298e47b3fd4 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 123 1.0E-18 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 NPD12_1038 5cef089ed32194989e5e58b65e1011bf 65 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 60 2.0E-8 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal NPD12_535 23010f2cf8759b1a9331445a4866b5fb 199 PIRSF PIRSF006102 1 199 1.8E-74 T 12-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 NPD12_535 23010f2cf8759b1a9331445a4866b5fb 199 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 1 197 26.265 T 12-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 NPD12_535 23010f2cf8759b1a9331445a4866b5fb 199 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 7 194 2.9E-81 T 12-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 NPD12_535 23010f2cf8759b1a9331445a4866b5fb 199 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 187 5.8E-67 T 12-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 NPD12_2779 e57b65bd639a2d0ab399d289debd2752 119 Pfam PF00072 Response regulator receiver domain 4 115 4.3E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2779 e57b65bd639a2d0ab399d289debd2752 119 SUPERFAMILY SSF52172 1 118 1.85E-41 T 12-10-2018 IPR011006 CheY-like superfamily NPD12_2779 e57b65bd639a2d0ab399d289debd2752 119 SMART SM00448 2 114 2.1E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 NPD12_2779 e57b65bd639a2d0ab399d289debd2752 119 Gene3D G3DSA:3.40.50.2300 1 119 6.0E-41 T 12-10-2018 NPD12_549 79bd748879293dd815c1ea66239961d3 303 Gene3D G3DSA:3.40.190.10 44 300 1.1E-58 T 12-10-2018 NPD12_549 79bd748879293dd815c1ea66239961d3 303 Gene3D G3DSA:3.40.190.10 129 265 1.1E-58 T 12-10-2018 NPD12_549 79bd748879293dd815c1ea66239961d3 303 SUPERFAMILY SSF53850 43 302 5.34E-58 T 12-10-2018 NPD12_549 79bd748879293dd815c1ea66239961d3 303 Pfam PF12849 PBP superfamily domain 33 285 1.7E-29 T 12-10-2018 IPR024370 PBP domain NPD12_3286 ae06e986f4fbb858d04db589f181b33a 311 Pfam PF02631 RecX family 88 205 5.4E-23 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 NPD12_3286 ae06e986f4fbb858d04db589f181b33a 311 Pfam PF02631 RecX family 235 304 1.7E-4 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 NPD12_3286 ae06e986f4fbb858d04db589f181b33a 311 Gene3D G3DSA:1.10.10.10 109 149 8.7E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3286 ae06e986f4fbb858d04db589f181b33a 311 Hamap MF_01114 Regulatory protein RecX [recX]. 43 210 15.409 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 NPD12_3286 ae06e986f4fbb858d04db589f181b33a 311 Gene3D G3DSA:1.10.10.2800 2 108 5.2E-28 T 12-10-2018 NPD12_2105 046b381104a112c605ea79dfc8ae325a 159 Gene3D G3DSA:3.30.70.640 1 159 4.2E-68 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2105 046b381104a112c605ea79dfc8ae325a 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 151 8.5E-66 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2105 046b381104a112c605ea79dfc8ae325a 159 Pfam PF01967 MoaC family 14 149 2.7E-55 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2105 046b381104a112c605ea79dfc8ae325a 159 SUPERFAMILY SSF55040 10 154 4.84E-60 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_2105 046b381104a112c605ea79dfc8ae325a 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 1 157 36.38 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 NPD12_1628 f8663c80fd0e78ee661be6f5758b1217 217 SUPERFAMILY SSF52540 1 201 3.59E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1628 f8663c80fd0e78ee661be6f5758b1217 217 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1628 f8663c80fd0e78ee661be6f5758b1217 217 SMART SM00382 28 204 1.9E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1628 f8663c80fd0e78ee661be6f5758b1217 217 Gene3D G3DSA:3.40.50.300 1 217 7.2E-54 T 12-10-2018 NPD12_1628 f8663c80fd0e78ee661be6f5758b1217 217 Pfam PF00005 ABC transporter 19 151 1.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1282 542fad2b764a3eb68ab5b2afed25aef4 192 Pfam PF03180 NLPA lipoprotein 1 192 1.7E-77 T 12-10-2018 IPR004872 Lipoprotein NlpA family NPD12_1282 542fad2b764a3eb68ab5b2afed25aef4 192 Gene3D G3DSA:3.40.190.10 40 142 2.7E-81 T 12-10-2018 NPD12_1282 542fad2b764a3eb68ab5b2afed25aef4 192 Gene3D G3DSA:3.40.190.10 1 190 2.7E-81 T 12-10-2018 NPD12_1282 542fad2b764a3eb68ab5b2afed25aef4 192 SUPERFAMILY SSF53850 1 192 5.91E-68 T 12-10-2018 NPD12_689 181b106b97aedf700e80d120320c0550 413 PIRSF PIRSF037420 78 309 5.9E-36 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E NPD12_689 181b106b97aedf700e80d120320c0550 413 PIRSF PIRSF037420 284 406 6.8E-5 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E NPD12_689 181b106b97aedf700e80d120320c0550 413 Gene3D G3DSA:3.20.20.70 84 389 1.1E-51 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_689 181b106b97aedf700e80d120320c0550 413 SUPERFAMILY SSF102114 94 382 1.11E-51 T 12-10-2018 NPD12_689 181b106b97aedf700e80d120320c0550 413 Pfam PF13394 4Fe-4S single cluster domain 96 200 1.5E-14 T 12-10-2018 NPD12_689 181b106b97aedf700e80d120320c0550 413 Pfam PF04055 Radical SAM superfamily 98 239 2.2E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_689 181b106b97aedf700e80d120320c0550 413 SMART SM00729 92 297 0.0043 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_689 181b106b97aedf700e80d120320c0550 413 Pfam PF13186 Iron-sulfur cluster-binding domain 308 376 6.2E-7 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_689 181b106b97aedf700e80d120320c0550 413 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 308 390 3.8E-11 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain NPD12_3599 f5348b1cb1a7eec5308f17663688cd7a 184 SUPERFAMILY SSF117457 3 174 4.45E-66 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 NPD12_3599 f5348b1cb1a7eec5308f17663688cd7a 184 Gene3D G3DSA:3.20.130.10 1 175 5.8E-74 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 NPD12_3599 f5348b1cb1a7eec5308f17663688cd7a 184 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 13 174 5.7E-55 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 NPD12_3599 f5348b1cb1a7eec5308f17663688cd7a 184 Pfam PF05683 Fumarase C-terminus 2 175 7.1E-64 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 NPD12_711 ea002025d7669ea6a14597e339e8a29e 141 Gene3D G3DSA:1.20.120.490 25 141 2.5E-31 T 12-10-2018 IPR024042 TM1646-like domain superfamily NPD12_711 ea002025d7669ea6a14597e339e8a29e 141 Pfam PF03885 Protein of unknown function (DUF327) 13 140 3.9E-39 T 12-10-2018 IPR005585 Protein of unknown function DUF327 NPD12_711 ea002025d7669ea6a14597e339e8a29e 141 SUPERFAMILY SSF158397 26 140 4.05E-35 T 12-10-2018 IPR024042 TM1646-like domain superfamily NPD12_2125 866e8f4082376a18fb022fa57c0af6b6 196 SUPERFAMILY SSF46689 12 76 6.14E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2125 866e8f4082376a18fb022fa57c0af6b6 196 Gene3D G3DSA:1.10.357.10 10 180 5.5E-34 T 12-10-2018 NPD12_2125 866e8f4082376a18fb022fa57c0af6b6 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 63 2.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 NPD12_3612 94af592bf8a8ca782b752ca7dbfac59b 132 SUPERFAMILY SSF53137 17 132 3.66E-49 T 12-10-2018 NPD12_3612 94af592bf8a8ca782b752ca7dbfac59b 132 Pfam PF00411 Ribosomal protein S11 22 131 2.5E-49 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 NPD12_3612 94af592bf8a8ca782b752ca7dbfac59b 132 PIRSF PIRSF002131 2 132 1.1E-52 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 NPD12_3612 94af592bf8a8ca782b752ca7dbfac59b 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 132 34.015 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 NPD12_3612 94af592bf8a8ca782b752ca7dbfac59b 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 100 122 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site NPD12_3612 94af592bf8a8ca782b752ca7dbfac59b 132 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 13 129 1.6E-58 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 NPD12_3612 94af592bf8a8ca782b752ca7dbfac59b 132 Gene3D G3DSA:3.30.420.80 5 132 2.0E-53 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 NPD12_2641 f70afc7475579a3cdd6784d7a4d00349 413 Gene3D G3DSA:3.40.640.10 35 285 9.6E-191 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 NPD12_2641 f70afc7475579a3cdd6784d7a4d00349 413 Pfam PF00464 Serine hydroxymethyltransferase 6 382 5.4E-179 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 NPD12_2641 f70afc7475579a3cdd6784d7a4d00349 413 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 411 54.162 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 NPD12_2641 f70afc7475579a3cdd6784d7a4d00349 413 SUPERFAMILY SSF53383 5 411 3.22E-183 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase NPD12_2641 f70afc7475579a3cdd6784d7a4d00349 413 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 NPD12_2641 f70afc7475579a3cdd6784d7a4d00349 413 PIRSF PIRSF000412 1 412 3.1E-169 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 NPD12_2641 f70afc7475579a3cdd6784d7a4d00349 413 Gene3D G3DSA:3.90.1150.10 8 391 9.6E-191 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 NPD12_2753 1ff5e24ea223db7cacdfc14ba4b35878 330 SUPERFAMILY SSF51735 2 322 1.64E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2753 1ff5e24ea223db7cacdfc14ba4b35878 330 Gene3D G3DSA:3.90.25.10 189 319 7.4E-92 T 12-10-2018 NPD12_2753 1ff5e24ea223db7cacdfc14ba4b35878 330 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 312 1.7E-73 T 12-10-2018 IPR016040 NAD(P)-binding domain NPD12_2753 1ff5e24ea223db7cacdfc14ba4b35878 330 Gene3D G3DSA:3.40.50.720 8 306 7.4E-92 T 12-10-2018 NPD12_2753 1ff5e24ea223db7cacdfc14ba4b35878 330 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 8 304 4.1E-160 T 12-10-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family NPD12_3337 f418ac7e924be1c2ddb608f4ed946f49 241 Pfam PF02517 CAAX protease self-immunity 142 231 7.8E-15 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_3536 1a28476164d8c4657b3fdbe25eb3806a 202 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 191 9.5E-38 T 12-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase NPD12_132 a349eaea7f1b5da1063596b251762734 87 Pfam PF04025 Domain of unknown function (DUF370) 2 79 1.7E-8 T 12-10-2018 IPR007169 Extracellular matrix regulatory protein A NPD12_91 ddfe2b01ed7e8c866a823a2ad4cc0a59 124 SUPERFAMILY SSF51735 6 121 2.66E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_91 ddfe2b01ed7e8c866a823a2ad4cc0a59 124 Pfam PF13380 CoA binding domain 10 120 4.9E-22 T 12-10-2018 IPR003781 CoA-binding GO:0048037 NPD12_91 ddfe2b01ed7e8c866a823a2ad4cc0a59 124 Gene3D G3DSA:3.40.50.720 7 123 3.3E-25 T 12-10-2018 NPD12_91 ddfe2b01ed7e8c866a823a2ad4cc0a59 124 SMART SM00881 6 95 0.0024 T 12-10-2018 IPR003781 CoA-binding GO:0048037 NPD12_1034 a4b8f3d8cb9cdf95a81e0021629a6701 99 Pfam PF00583 Acetyltransferase (GNAT) family 7 69 2.1E-9 T 12-10-2018 IPR000182 GNAT domain NPD12_1034 a4b8f3d8cb9cdf95a81e0021629a6701 99 Gene3D G3DSA:3.40.630.30 1 98 1.2E-16 T 12-10-2018 NPD12_1034 a4b8f3d8cb9cdf95a81e0021629a6701 99 SUPERFAMILY SSF55729 8 81 9.61E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_130 fd4c164ac9e03443d8e0e1949e2702ba 68 SUPERFAMILY SSF55174 1 67 3.79E-19 T 12-10-2018 NPD12_130 fd4c164ac9e03443d8e0e1949e2702ba 68 Gene3D G3DSA:3.10.290.10 1 68 7.8E-23 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 NPD12_130 fd4c164ac9e03443d8e0e1949e2702ba 68 Pfam PF13275 S4 domain 4 67 4.1E-25 T 12-10-2018 NPD12_130 fd4c164ac9e03443d8e0e1949e2702ba 68 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 3 62 5.9E-26 T 12-10-2018 IPR014330 RNA-binding S4-related,YaaA NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 SUPERFAMILY SSF51905 1 324 2.76E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 Gene3D G3DSA:3.50.50.60 121 255 2.3E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 4.6E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 205 221 4.6E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 4.6E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 4.6E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 4.6E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 4.6E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.5E-18 T 12-10-2018 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 2.5E-18 T 12-10-2018 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 2.5E-18 T 12-10-2018 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 2.5E-18 T 12-10-2018 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 310 4.8E-30 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 NPD12_3443 97c815072a0b0e931722ac35bc0f8447 418 Gene3D G3DSA:3.50.50.60 5 298 2.3E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_3516 c674567d2c132fe5731c683ab5bfa5a5 140 Pfam PF13411 MerR HTH family regulatory protein 3 68 1.4E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_3516 c674567d2c132fe5731c683ab5bfa5a5 140 SMART SM00422 3 72 2.1E-22 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_3516 c674567d2c132fe5731c683ab5bfa5a5 140 SUPERFAMILY SSF46955 3 117 3.33E-32 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_3516 c674567d2c132fe5731c683ab5bfa5a5 140 Gene3D G3DSA:1.10.1660.10 1 128 5.0E-35 T 12-10-2018 NPD12_577 da81cdad22fa2980a4966d06cba8bf2a 371 SUPERFAMILY SSF54001 68 186 3.34E-6 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 1 348 33.623 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 SUPERFAMILY SSF56014 261 346 4.07E-13 T 12-10-2018 NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 PIRSF PIRSF004640 1 349 2.2E-150 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 Gene3D G3DSA:3.30.413.10 256 349 2.9E-39 T 12-10-2018 NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3 346 1.3E-130 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 Gene3D G3DSA:3.20.20.20 1 254 2.7E-107 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 SUPERFAMILY SSF51717 11 226 1.8E-12 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_2472 04d249a2955dd3772046a39fe3baa7f6 349 Pfam PF04551 GcpE protein 6 348 5.6E-143 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 NPD12_756 e7e114abb979ab9dfe6eb812cd9169c8 41 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 33 1.3E-16 T 12-10-2018 IPR027601 Cys-rich peptide, Clo7bot family NPD12_1486 a7bcb8d24d6d7c0dc52f74b3b92f3758 480 TIGRFAM TIGR01538 portal_SPP1: phage portal protein, SPP1 family 21 457 3.2E-59 T 12-10-2018 IPR006428 Portal protein, SPP1-type NPD12_1486 a7bcb8d24d6d7c0dc52f74b3b92f3758 480 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 31 461 2.7E-88 T 12-10-2018 IPR021145 Portal protein NPD12_3212 51fcc33adca474ac695004a1181c6ebd 472 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 68 433 1.6E-11 T 12-10-2018 NPD12_2112 c3a1cbaefb136fa4e284e6e1970e736f 283 SUPERFAMILY SSF53850 40 269 6.16E-33 T 12-10-2018 NPD12_2112 c3a1cbaefb136fa4e284e6e1970e736f 283 Gene3D G3DSA:3.40.190.10 40 265 7.7E-92 T 12-10-2018 NPD12_2112 c3a1cbaefb136fa4e284e6e1970e736f 283 Pfam PF12849 PBP superfamily domain 29 259 2.1E-34 T 12-10-2018 IPR024370 PBP domain NPD12_2112 c3a1cbaefb136fa4e284e6e1970e736f 283 Gene3D G3DSA:3.40.190.10 115 229 7.7E-92 T 12-10-2018 NPD12_1257 f1177ae1384b4c7f646d6900b7a92d04 117 Pfam PF08239 Bacterial SH3 domain 63 112 1.5E-13 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_1257 f1177ae1384b4c7f646d6900b7a92d04 117 Gene3D G3DSA:2.30.30.40 57 114 3.1E-15 T 12-10-2018 NPD12_1257 f1177ae1384b4c7f646d6900b7a92d04 117 SMART SM00287 54 117 8.5E-9 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type NPD12_3606 6d18b3d7aa2ea0a33f4f7a1139e303fa 267 Pfam PF02361 Cobalt transport protein 15 235 4.2E-53 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component NPD12_3606 6d18b3d7aa2ea0a33f4f7a1139e303fa 267 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 36.547 T 12-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 NPD12_1316 efd89b5fcb1340dc2267bd1176912be3 259 SUPERFAMILY SSF52151 14 208 4.19E-7 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase NPD12_1316 efd89b5fcb1340dc2267bd1176912be3 259 Gene3D G3DSA:3.40.1090.10 11 92 5.3E-6 T 12-10-2018 NPD12_2877 fca59508b93dbff7a87453bb68a8e838 84 SUPERFAMILY SSF52728 66 83 9.55E-6 T 12-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 NPD12_2877 fca59508b93dbff7a87453bb68a8e838 84 Pfam PF03830 PTS system sorbose subfamily IIB component 68 83 1.3E-4 T 12-10-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 NPD12_1507 82221010048123efed3200a460d2a07f 208 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 4 140 1.6E-16 T 12-10-2018 IPR018755 Bacteriophage Mu-like, Gp48 NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 Gene3D G3DSA:3.40.950.20 260 480 5.9E-44 T 12-10-2018 NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 TIGRFAM TIGR04105 FeFe_hydrog_B1: [FeFe] hydrogenase, group B1/B3 4 459 7.2E-189 T 12-10-2018 IPR027631 [FeFe] hydrogenase, group B1/B3 NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 SUPERFAMILY SSF53920 187 460 4.84E-71 T 12-10-2018 IPR009016 Iron hydrogenase NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 SUPERFAMILY SSF54862 131 209 1.95E-19 T 12-10-2018 NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 220 454 3.2E-65 T 12-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 Gene3D G3DSA:3.30.70.20 103 161 5.3E-12 T 12-10-2018 NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 Gene3D G3DSA:3.30.70.20 162 208 2.9E-13 T 12-10-2018 NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 Pfam PF00037 4Fe-4S binding domain 135 156 1.8E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_3430 b9ba8e830bcef7b65ccf567f5142a96e 497 Pfam PF12838 4Fe-4S dicluster domain 163 202 9.1E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2266 422bfc66404cea7ce025ac4ec1398f2e 262 SUPERFAMILY SSF103032 6 262 3.92E-72 T 12-10-2018 IPR035948 YwqG-like superfamily NPD12_2266 422bfc66404cea7ce025ac4ec1398f2e 262 Gene3D G3DSA:2.30.320.10 3 262 4.2E-91 T 12-10-2018 IPR035948 YwqG-like superfamily NPD12_2266 422bfc66404cea7ce025ac4ec1398f2e 262 Pfam PF09234 Domain of unknown function (DUF1963) 41 261 2.1E-62 T 12-10-2018 IPR015315 Protein of unknown function DUF1963 NPD12_3614 608809e732b4bd5a9ebf3fc55cc4543b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3614 608809e732b4bd5a9ebf3fc55cc4543b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.611 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3614 608809e732b4bd5a9ebf3fc55cc4543b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 5.8E-24 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3614 608809e732b4bd5a9ebf3fc55cc4543b 37 Pfam PF00444 Ribosomal protein L36 1 37 3.2E-19 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3614 608809e732b4bd5a9ebf3fc55cc4543b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 2.0E-8 T 12-10-2018 NPD12_3614 608809e732b4bd5a9ebf3fc55cc4543b 37 SUPERFAMILY SSF57840 1 37 6.28E-17 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 NPD12_3033 f581833ad4d8114fd4acb494d9c4b772 364 Pfam PF04865 Baseplate J-like protein 64 320 6.8E-54 T 12-10-2018 IPR006949 Baseplate protein J-like NPD12_249 66f791745f5e6b0d2c9b5720f13b427c 713 Gene3D G3DSA:3.20.70.20 120 686 2.1E-185 T 12-10-2018 NPD12_249 66f791745f5e6b0d2c9b5720f13b427c 713 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 114 701 4.6E-183 T 12-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 NPD12_249 66f791745f5e6b0d2c9b5720f13b427c 713 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 114 702 2.2E-197 T 12-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 NPD12_249 66f791745f5e6b0d2c9b5720f13b427c 713 SUPERFAMILY SSF51998 115 685 1.59E-158 T 12-10-2018 NPD12_249 66f791745f5e6b0d2c9b5720f13b427c 713 Pfam PF03477 ATP cone domain 3 91 1.7E-18 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 NPD12_2819 8c056ccf3c2179a8844ff60a5539ef4c 106 Gene3D G3DSA:3.30.110.70 2 106 2.8E-41 T 12-10-2018 NPD12_2819 8c056ccf3c2179a8844ff60a5539ef4c 106 SUPERFAMILY SSF117782 1 106 2.22E-39 T 12-10-2018 IPR035439 UPF0145 domain superfamily NPD12_2819 8c056ccf3c2179a8844ff60a5539ef4c 106 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 23.948 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 NPD12_2819 8c056ccf3c2179a8844ff60a5539ef4c 106 Pfam PF01906 Putative heavy-metal-binding 1 104 2.2E-40 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 NPD12_3595 86bd56c4f29438a618576a172846f601 246 Pfam PF15525 Domain of unknown function (DUF4652) 33 237 2.3E-83 T 12-10-2018 IPR028102 Protein of unknown function DUF4652 NPD12_3595 86bd56c4f29438a618576a172846f601 246 Gene3D G3DSA:2.40.128.660 70 239 7.0E-54 T 12-10-2018 NPD12_977 4ca26b968dcb853c7d6b9fcf613ef3b3 256 SMART SM00382 26 215 2.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_977 4ca26b968dcb853c7d6b9fcf613ef3b3 256 Gene3D G3DSA:3.40.50.300 1 248 1.3E-67 T 12-10-2018 NPD12_977 4ca26b968dcb853c7d6b9fcf613ef3b3 256 SUPERFAMILY SSF52540 1 228 9.63E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_977 4ca26b968dcb853c7d6b9fcf613ef3b3 256 Pfam PF00005 ABC transporter 17 166 1.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_977 4ca26b968dcb853c7d6b9fcf613ef3b3 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1563 aef943ac0719e4e68d13a58a38f85dec 154 SUPERFAMILY SSF50475 1 152 1.51E-43 T 12-10-2018 NPD12_1563 aef943ac0719e4e68d13a58a38f85dec 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 14 151 1.5E-19 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related NPD12_1563 aef943ac0719e4e68d13a58a38f85dec 154 Gene3D G3DSA:2.30.110.10 2 153 1.8E-39 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_793 14883ff712381d88ef330aa324a4cd1b 392 Gene3D G3DSA:3.40.50.150 112 381 9.9E-97 T 12-10-2018 NPD12_793 14883ff712381d88ef330aa324a4cd1b 392 Pfam PF02353 Mycolic acid cyclopropane synthetase 105 373 1.8E-99 T 12-10-2018 NPD12_793 14883ff712381d88ef330aa324a4cd1b 392 SUPERFAMILY SSF53335 3 331 1.24E-80 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_793 14883ff712381d88ef330aa324a4cd1b 392 PIRSF PIRSF003085 2 392 2.0E-123 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 NPD12_2707 d1bdb123382c3298525d3bd4174dd395 462 Pfam PF02120 Flagellar hook-length control protein FliK 335 414 7.7E-16 T 12-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal NPD12_2707 d1bdb123382c3298525d3bd4174dd395 462 Gene3D G3DSA:3.30.750.140 315 433 4.3E-10 T 12-10-2018 IPR038610 FliK-like, C-terminal domain superfamily NPD12_3302 e028d7ed027de22e1b5c3554986a6585 361 Gene3D G3DSA:3.40.50.10690 119 361 1.7E-86 T 12-10-2018 NPD12_3302 e028d7ed027de22e1b5c3554986a6585 361 Gene3D G3DSA:2.40.420.10 16 95 1.5E-11 T 12-10-2018 NPD12_1599 7c9a4debbb2fa7db2798a2f36fd2ef5e 324 SUPERFAMILY SSF103481 194 299 2.75E-15 T 12-10-2018 NPD12_1599 7c9a4debbb2fa7db2798a2f36fd2ef5e 324 Gene3D G3DSA:1.10.3730.20 191 303 3.1E-5 T 12-10-2018 NPD12_1599 7c9a4debbb2fa7db2798a2f36fd2ef5e 324 Pfam PF00892 EamA-like transporter family 158 296 2.0E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_1599 7c9a4debbb2fa7db2798a2f36fd2ef5e 324 Pfam PF00892 EamA-like transporter family 10 144 6.6E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_1599 7c9a4debbb2fa7db2798a2f36fd2ef5e 324 SUPERFAMILY SSF103481 52 144 7.32E-12 T 12-10-2018 NPD12_1902 c8d93a3accff705263623abe72ca06c2 277 Pfam PF06161 Protein of unknown function (DUF975) 8 265 6.5E-47 T 12-10-2018 IPR010380 Protein of unknown function DUF975 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 SUPERFAMILY SSF161070 5 477 1.44E-149 T 12-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 29 43 - T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 Pfam PF00209 Sodium:neurotransmitter symporter family 125 477 1.7E-79 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 313 332 2.6E-23 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 2.6E-23 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 2.6E-23 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 86 112 2.6E-23 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 NPD12_2191 6ed2489900d4bdc10d1430fc22cb1bb4 497 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 390 410 2.6E-23 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 NPD12_2723 d82cd158a00326acd16c66043b6a44df 296 Pfam PF06081 Aromatic acid exporter family member 1 3 144 1.3E-26 T 12-10-2018 IPR010343 Aromatic acid exporter family member 1 NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 SMART SM00382 30 217 9.3E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 Pfam PF00571 CBS domain 254 304 1.1E-9 T 12-10-2018 IPR000644 CBS domain NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 Pfam PF00571 CBS domain 314 369 4.7E-10 T 12-10-2018 IPR000644 CBS domain NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 20 370 3.6E-123 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 Gene3D G3DSA:3.40.50.300 1 244 2.4E-77 T 12-10-2018 NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 Gene3D G3DSA:3.10.580.10 251 373 1.4E-29 T 12-10-2018 NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 Pfam PF00005 ABC transporter 22 167 4.1E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 SUPERFAMILY SSF52540 5 246 3.84E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 SUPERFAMILY SSF54631 252 368 3.41E-28 T 12-10-2018 NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 SMART SM00116 321 369 1.4E-6 T 12-10-2018 IPR000644 CBS domain NPD12_1875 113190f9d7a3160d512584f95ef36a44 381 SMART SM00116 261 309 2.9E-5 T 12-10-2018 IPR000644 CBS domain NPD12_393 8333c8646091c693bf6579eff92423b6 387 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 4.3E-8 T 12-10-2018 NPD12_393 8333c8646091c693bf6579eff92423b6 387 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 4.3E-8 T 12-10-2018 NPD12_393 8333c8646091c693bf6579eff92423b6 387 PRINTS PR00173 Glutamate-aspartate symporter signature 335 355 4.3E-8 T 12-10-2018 NPD12_393 8333c8646091c693bf6579eff92423b6 387 PRINTS PR00173 Glutamate-aspartate symporter signature 271 297 4.3E-8 T 12-10-2018 NPD12_393 8333c8646091c693bf6579eff92423b6 387 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 4.3E-8 T 12-10-2018 NPD12_393 8333c8646091c693bf6579eff92423b6 387 Pfam PF00375 Sodium:dicarboxylate symporter family 8 378 3.5E-73 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 NPD12_393 8333c8646091c693bf6579eff92423b6 387 SUPERFAMILY SSF118215 8 378 1.44E-69 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_393 8333c8646091c693bf6579eff92423b6 387 Gene3D G3DSA:1.10.3860.10 1 384 2.4E-46 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 NPD12_2632 2dd40c7a800fdf7795fdde837267705c 285 SUPERFAMILY SSF53474 5 276 2.62E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2632 2dd40c7a800fdf7795fdde837267705c 285 Pfam PF00975 Thioesterase domain 5 276 3.3E-11 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 NPD12_444 52a691369c476d924a57b67c360987ce 523 SUPERFAMILY SSF55604 448 521 1.7E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_444 52a691369c476d924a57b67c360987ce 523 Pfam PF02378 Phosphotransferase system, EIIC 14 348 2.4E-59 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_444 52a691369c476d924a57b67c360987ce 523 Gene3D G3DSA:3.30.1360.60 444 523 5.5E-27 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 NPD12_444 52a691369c476d924a57b67c360987ce 523 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 407 507 5.9E-20 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 NPD12_444 52a691369c476d924a57b67c360987ce 523 Pfam PF00367 phosphotransferase system, EIIB 452 483 3.3E-13 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_444 52a691369c476d924a57b67c360987ce 523 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 461 478 - T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 NPD12_2948 41a16286dc5a76dd60ad7365265f3a68 264 Gene3D G3DSA:3.40.50.300 1 257 7.9E-60 T 12-10-2018 NPD12_2948 41a16286dc5a76dd60ad7365265f3a68 264 SUPERFAMILY SSF52540 3 227 5.01E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2948 41a16286dc5a76dd60ad7365265f3a68 264 SMART SM00382 27 216 1.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2948 41a16286dc5a76dd60ad7365265f3a68 264 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_2948 41a16286dc5a76dd60ad7365265f3a68 264 Pfam PF00005 ABC transporter 19 167 2.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3525 cba578b5f02ef3debc4834b4cb3f9c9b 117 Pfam PF07561 Domain of Unknown Function (DUF1540) 73 113 7.9E-10 T 12-10-2018 IPR011437 Domain of unknown function DUF1540 NPD12_3525 cba578b5f02ef3debc4834b4cb3f9c9b 117 Pfam PF07561 Domain of Unknown Function (DUF1540) 6 38 2.0E-5 T 12-10-2018 IPR011437 Domain of unknown function DUF1540 NPD12_3507 4f09e1c0abd2104ee922feaa2f43c58e 199 SUPERFAMILY SSF56349 7 192 1.41E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 NPD12_3507 4f09e1c0abd2104ee922feaa2f43c58e 199 Gene3D G3DSA:1.10.443.10 4 199 3.0E-40 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 NPD12_3507 4f09e1c0abd2104ee922feaa2f43c58e 199 Pfam PF00589 Phage integrase family 10 179 9.2E-33 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 NPD12_1056 04b2fa5d3f923a228392c93e7e89dd41 172 SUPERFAMILY SSF55469 1 172 2.09E-49 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_1056 04b2fa5d3f923a228392c93e7e89dd41 172 Gene3D G3DSA:3.40.109.10 2 172 5.7E-49 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_1056 04b2fa5d3f923a228392c93e7e89dd41 172 Pfam PF00881 Nitroreductase family 67 146 3.3E-12 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_1056 04b2fa5d3f923a228392c93e7e89dd41 172 Pfam PF00881 Nitroreductase family 8 59 5.7E-12 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_1307 93b96ea833fa56276f57dfc088e77a8e 92 Gene3D G3DSA:1.20.1530.20 1 92 2.6E-5 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_1307 93b96ea833fa56276f57dfc088e77a8e 92 Pfam PF03956 Lysine exporter LysO 5 82 2.8E-7 T 12-10-2018 IPR005642 Lysine exporter LysO NPD12_1644 2dd386f4d8c6f9d5fa1c67c69f5f1836 312 Pfam PF13732 Domain of unknown function (DUF4162) 217 305 3.2E-6 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 NPD12_1644 2dd386f4d8c6f9d5fa1c67c69f5f1836 312 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1644 2dd386f4d8c6f9d5fa1c67c69f5f1836 312 SMART SM00382 28 212 1.9E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1644 2dd386f4d8c6f9d5fa1c67c69f5f1836 312 SUPERFAMILY SSF52540 3 222 2.15E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1644 2dd386f4d8c6f9d5fa1c67c69f5f1836 312 Pfam PF00005 ABC transporter 19 162 3.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1644 2dd386f4d8c6f9d5fa1c67c69f5f1836 312 Gene3D G3DSA:3.40.50.300 1 236 3.0E-68 T 12-10-2018 NPD12_679 277cb4358eadec197dd9fb6dc1787098 63 SUPERFAMILY SSF47240 3 61 1.55E-5 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_1482 d2affbf79fe6960d50bf495a834a7f7c 145 SUPERFAMILY SSF88659 81 136 7.48E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_1482 d2affbf79fe6960d50bf495a834a7f7c 145 Gene3D G3DSA:1.20.140.160 4 139 5.8E-10 T 12-10-2018 NPD12_1731 3b4efe9e9dfeb0c394d7b343642c8848 181 Gene3D G3DSA:3.40.1050.10 16 177 8.6E-10 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 NPD12_1731 3b4efe9e9dfeb0c394d7b343642c8848 181 SUPERFAMILY SSF53056 24 178 5.1E-10 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 NPD12_1731 3b4efe9e9dfeb0c394d7b343642c8848 181 SMART SM00947 36 178 2.7E-7 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 Gene3D G3DSA:1.10.8.410 232 279 1.9E-18 T 12-10-2018 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 Gene3D G3DSA:1.20.1330.10 187 231 1.0E-8 T 12-10-2018 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 Pfam PF00700 Bacterial flagellin C-terminal helical region 194 278 1.5E-17 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 Gene3D G3DSA:1.20.1330.10 43 174 3.1E-64 T 12-10-2018 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 Gene3D G3DSA:1.20.58.1830 3 31 3.1E-64 T 12-10-2018 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 1.1E-41 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 PRINTS PR00207 Flagellin signature 109 132 1.5E-19 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 PRINTS PR00207 Flagellin signature 35 52 1.5E-19 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 PRINTS PR00207 Flagellin signature 74 93 1.5E-19 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 NPD12_404 169b1445e20abe58045e92f85a8e0035 283 SUPERFAMILY SSF64518 1 278 9.94E-85 T 12-10-2018 NPD12_396 68c31004ad0e1cbd533589905be475be 458 Gene3D G3DSA:3.90.110.10 171 444 1.5E-90 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_396 68c31004ad0e1cbd533589905be475be 458 Gene3D G3DSA:3.40.50.720 1 170 2.1E-66 T 12-10-2018 NPD12_396 68c31004ad0e1cbd533589905be475be 458 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 9.3E-49 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 9.3E-49 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 9.3E-49 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 9.3E-49 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 9.3E-49 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 9.3E-49 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 9.3E-49 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 Pfam PF02056 Family 4 glycosyl hydrolase 6 179 2.0E-64 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 NPD12_396 68c31004ad0e1cbd533589905be475be 458 SUPERFAMILY SSF51735 4 168 7.43E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_396 68c31004ad0e1cbd533589905be475be 458 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 411 1.5E-46 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 NPD12_396 68c31004ad0e1cbd533589905be475be 458 SUPERFAMILY SSF56327 173 437 1.12E-80 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 NPD12_1544 143c314d5e369cadd1c378384ec49b70 281 Gene3D G3DSA:3.30.70.270 117 279 1.9E-23 T 12-10-2018 NPD12_1544 143c314d5e369cadd1c378384ec49b70 281 SUPERFAMILY SSF55073 134 275 2.2E-19 T 12-10-2018 IPR029787 Nucleotide cyclase NPD12_1544 143c314d5e369cadd1c378384ec49b70 281 SMART SM00267 117 279 1.8E-7 T 12-10-2018 IPR000160 GGDEF domain NPD12_1544 143c314d5e369cadd1c378384ec49b70 281 Pfam PF00990 Diguanylate cyclase, GGDEF domain 130 266 7.8E-22 T 12-10-2018 IPR000160 GGDEF domain NPD12_1544 143c314d5e369cadd1c378384ec49b70 281 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 129 277 1.7E-19 T 12-10-2018 IPR000160 GGDEF domain NPD12_2365 d5a9d79a8c8ebc4e49e0b7a0c7c54071 134 Pfam PF10990 Protein of unknown function (DUF2809) 32 115 2.7E-30 T 12-10-2018 IPR021257 Protein of unknown function DUF2809 NPD12_1641 c7bbb65b098c049e15165c9989ec2c93 125 Pfam PF08000 Bacterial PH domain 2 123 4.7E-52 T 12-10-2018 IPR012544 Bacterial Pleckstrin homology domain NPD12_1641 c7bbb65b098c049e15165c9989ec2c93 125 Gene3D G3DSA:2.30.29.50 1 125 4.2E-54 T 12-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily NPD12_1641 c7bbb65b098c049e15165c9989ec2c93 125 SUPERFAMILY SSF50729 6 124 2.87E-46 T 12-10-2018 NPD12_2601 f9a54c75469409f4fefcfb70ab6c40e4 405 Pfam PF01136 Peptidase family U32 77 309 4.0E-102 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 NPD12_2601 f9a54c75469409f4fefcfb70ab6c40e4 405 ProSitePatterns PS01276 Peptidase family U32 signature. 163 181 - T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 NPD12_2601 f9a54c75469409f4fefcfb70ab6c40e4 405 Pfam PF16325 Peptidase family U32 C-terminal domain 320 401 3.5E-20 T 12-10-2018 IPR032525 Peptidase family U32, C-terminal NPD12_2601 f9a54c75469409f4fefcfb70ab6c40e4 405 Gene3D G3DSA:2.40.30.10 318 405 2.3E-22 T 12-10-2018 NPD12_1727 d1e7cc0dc64596595a0aaa1882e08cb3 178 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 37.678 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 NPD12_1727 d1e7cc0dc64596595a0aaa1882e08cb3 178 Gene3D G3DSA:3.40.50.2020 2 178 1.5E-59 T 12-10-2018 NPD12_1727 d1e7cc0dc64596595a0aaa1882e08cb3 178 SUPERFAMILY SSF53271 6 171 5.24E-43 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_1727 d1e7cc0dc64596595a0aaa1882e08cb3 178 Pfam PF00156 Phosphoribosyl transferase domain 6 160 1.0E-22 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_2235 5eb893ccdf82772b9460892bca19f505 306 Pfam PF03547 Membrane transport protein 5 143 4.5E-15 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 NPD12_2784 a328b66afd83a5fcaba9d0a64446f26a 162 Pfam PF03975 CheD chemotactic sensory transduction 49 154 4.1E-38 T 12-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 NPD12_2784 a328b66afd83a5fcaba9d0a64446f26a 162 Gene3D G3DSA:3.30.1330.200 3 162 1.1E-50 T 12-10-2018 IPR038592 CheD-like superfamily NPD12_2784 a328b66afd83a5fcaba9d0a64446f26a 162 SUPERFAMILY SSF64438 5 160 6.23E-51 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic NPD12_2784 a328b66afd83a5fcaba9d0a64446f26a 162 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 2 158 28.698 T 12-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 NPD12_2378 96f54c1003bc2146469167a3cdb9fcb8 242 Pfam PF00753 Metallo-beta-lactamase superfamily 24 224 3.5E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2378 96f54c1003bc2146469167a3cdb9fcb8 242 SUPERFAMILY SSF56281 23 238 2.62E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2378 96f54c1003bc2146469167a3cdb9fcb8 242 Gene3D G3DSA:3.60.15.10 8 242 2.2E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like NPD12_2378 96f54c1003bc2146469167a3cdb9fcb8 242 SMART SM00849 19 224 6.1E-31 T 12-10-2018 IPR001279 Metallo-beta-lactamase NPD12_2127 4c3d6105a066071dcd7395baa40fa106 739 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 150 429 3.6E-49 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 NPD12_2127 4c3d6105a066071dcd7395baa40fa106 739 SUPERFAMILY SSF55486 309 357 4.23E-5 T 12-10-2018 NPD12_3812 db7c238fed81bb2e290598f3a6f2a11d 81 Pfam PF12116 Stage III sporulation protein D 3 81 7.2E-32 T 12-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID NPD12_3812 db7c238fed81bb2e290598f3a6f2a11d 81 Gene3D G3DSA:1.10.10.60 1 81 4.4E-33 T 12-10-2018 NPD12_2798 97a88b3b7af0f169fb173b5c46f3f367 272 SMART SM00518 1 269 6.7E-54 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 NPD12_2798 97a88b3b7af0f169fb173b5c46f3f367 272 SUPERFAMILY SSF51658 4 271 4.97E-59 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily NPD12_2798 97a88b3b7af0f169fb173b5c46f3f367 272 Pfam PF01261 Xylose isomerase-like TIM barrel 28 232 2.2E-21 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain NPD12_2798 97a88b3b7af0f169fb173b5c46f3f367 272 Gene3D G3DSA:3.20.20.150 17 271 6.5E-37 T 12-10-2018 NPD12_745 f850bf12de1a138acbe902c5e153a33e 177 Gene3D G3DSA:1.10.10.10 106 171 1.7E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_745 f850bf12de1a138acbe902c5e153a33e 177 SUPERFAMILY SSF88659 114 171 4.3E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_745 f850bf12de1a138acbe902c5e153a33e 177 Pfam PF12645 Helix-turn-helix domain 6 46 1.1E-6 T 12-10-2018 IPR024760 Helix-turn-helix, conjugative transposon-like NPD12_745 f850bf12de1a138acbe902c5e153a33e 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 167 1.7E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_2198 7e918a1618b0da089061c00c0f82fd74 597 Gene3D G3DSA:3.50.50.60 10 142 1.1E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2198 7e918a1618b0da089061c00c0f82fd74 597 Gene3D G3DSA:3.50.50.60 469 548 3.0E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2198 7e918a1618b0da089061c00c0f82fd74 597 Gene3D G3DSA:3.30.9.80 334 468 3.9E-51 T 12-10-2018 NPD12_2198 7e918a1618b0da089061c00c0f82fd74 597 Pfam PF06100 MCRA family 32 531 2.3E-201 T 12-10-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 NPD12_2198 7e918a1618b0da089061c00c0f82fd74 597 SUPERFAMILY SSF51905 37 274 3.6E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_966 28516a242f83978ed25c14d3406d03f1 331 Pfam PF13170 Protein of unknown function (DUF4003) 15 312 2.5E-109 T 12-10-2018 IPR025062 Protein of unknown function DUF4003 NPD12_3502 68625d44abd73be08be6e07d18e5025d 103 SUPERFAMILY SSF52794 1 102 1.1E-36 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 NPD12_3502 68625d44abd73be08be6e07d18e5025d 103 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 95 4.2E-33 T 12-10-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 NPD12_3502 68625d44abd73be08be6e07d18e5025d 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 2.4E-23 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 NPD12_3502 68625d44abd73be08be6e07d18e5025d 103 Gene3D G3DSA:3.40.50.2300 2 103 3.5E-38 T 12-10-2018 NPD12_755 4ce416c9d7a33a44f68e4a7402b263d1 39 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 33 2.9E-18 T 12-10-2018 IPR027601 Cys-rich peptide, Clo7bot family NPD12_1911 d7cf992737bd2f615a9b5695b70df423 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 324 4.2E-44 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1911 d7cf992737bd2f615a9b5695b70df423 324 Gene3D G3DSA:1.10.3720.10 91 321 5.1E-22 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1911 d7cf992737bd2f615a9b5695b70df423 324 SUPERFAMILY SSF161098 99 312 1.7E-20 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1700 0186e0f7848030bd98de213f6c8c375b 308 Pfam PF04389 Peptidase family M28 141 291 8.1E-13 T 12-10-2018 IPR007484 Peptidase M28 NPD12_1700 0186e0f7848030bd98de213f6c8c375b 308 SUPERFAMILY SSF53187 26 294 4.54E-17 T 12-10-2018 NPD12_470 346373ad8894cf68e2c17021d8640c9d 442 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 415 1.1E-63 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_470 346373ad8894cf68e2c17021d8640c9d 442 Pfam PF01554 MatE 20 180 8.2E-34 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_470 346373ad8894cf68e2c17021d8640c9d 442 Pfam PF01554 MatE 245 403 3.7E-24 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_470 346373ad8894cf68e2c17021d8640c9d 442 PIRSF PIRSF006603 1 440 7.5E-93 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_1135 c5d8a70c0d5f526c23979b0135dd5940 243 Gene3D G3DSA:3.30.950.10 110 240 2.4E-48 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 NPD12_1135 c5d8a70c0d5f526c23979b0135dd5940 243 SUPERFAMILY SSF53790 1 240 4.32E-57 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 NPD12_1135 c5d8a70c0d5f526c23979b0135dd5940 243 Gene3D G3DSA:3.40.1010.10 1 109 1.2E-31 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 NPD12_1135 c5d8a70c0d5f526c23979b0135dd5940 243 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 4 239 1.0E-91 T 12-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 NPD12_1135 c5d8a70c0d5f526c23979b0135dd5940 243 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 205 1.8E-39 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 NPD12_687 ad73e13f8e9261bf79e157b4bceee7db 216 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 188 6.3E-24 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_687 ad73e13f8e9261bf79e157b4bceee7db 216 PIRSF PIRSF000349 3 197 6.4E-44 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_687 ad73e13f8e9261bf79e157b4bceee7db 216 SUPERFAMILY SSF54719 87 193 7.86E-31 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_687 ad73e13f8e9261bf79e157b4bceee7db 216 SUPERFAMILY SSF46609 6 82 1.54E-9 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_687 ad73e13f8e9261bf79e157b4bceee7db 216 Gene3D G3DSA:2.40.500.20 81 201 9.6E-28 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 NPD12_809 7793d3567b3ed563d74bf8c4cdbf0645 116 Pfam PF14198 Transposon-encoded protein TnpV 7 114 5.5E-25 T 12-10-2018 IPR026989 Transposon-encoded protein TnpV NPD12_1077 26f7825b42bbe7da90456c3e9eb2f12a 222 Pfam PF09557 Domain of unknown function (DUF2382) 95 200 4.4E-26 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_1077 26f7825b42bbe7da90456c3e9eb2f12a 222 TIGRFAM TIGR02271 TIGR02271: conserved domain 95 208 1.2E-30 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_2008 e748c67afa51256bee43fa73a778895b 146 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 33 116 6.7E-32 T 12-10-2018 IPR014229 Sporulation protein YtfJ NPD12_2008 e748c67afa51256bee43fa73a778895b 146 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 4 126 9.6E-63 T 12-10-2018 IPR014229 Sporulation protein YtfJ NPD12_2008 e748c67afa51256bee43fa73a778895b 146 PIRSF PIRSF021377 1 146 1.3E-63 T 12-10-2018 IPR014229 Sporulation protein YtfJ NPD12_1102 2eb137cdcdb45e3dfd737bfd4196248d 99 TIGRFAM TIGR01165 cbiN: cobalt transport protein 2 87 4.9E-33 T 12-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 NPD12_1102 2eb137cdcdb45e3dfd737bfd4196248d 99 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 99 42.38 T 12-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 NPD12_1102 2eb137cdcdb45e3dfd737bfd4196248d 99 Pfam PF02553 Cobalt transport protein component CbiN 5 73 4.6E-30 T 12-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 NPD12_660 ff96434ba55330e5f918bf585111cbd8 374 Pfam PF12698 ABC-2 family transporter protein 19 366 3.7E-34 T 12-10-2018 NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 Pfam PF03466 LysR substrate binding domain 90 281 1.4E-13 T 12-10-2018 IPR005119 LysR, substrate-binding NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 Gene3D G3DSA:3.40.190.290 89 288 1.8E-11 T 12-10-2018 NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 3.5E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 SUPERFAMILY SSF53850 90 281 4.21E-15 T 12-10-2018 NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 Gene3D G3DSA:1.10.10.10 1 82 1.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 NPD12_1160 d45a751cac04c442f3c27fe47842fea2 292 SUPERFAMILY SSF46785 2 85 1.73E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1219 3eb56b0dea24e6455033a22f00144512 258 SUPERFAMILY SSF55729 61 117 1.33E-5 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1219 3eb56b0dea24e6455033a22f00144512 258 Pfam PF14268 YoaP-like 203 245 7.6E-18 T 12-10-2018 IPR025685 YoaP-like domain NPD12_1017 2807f393d4f7e941e6261cc0372a88d8 146 Gene3D G3DSA:2.60.40.790 4 145 4.0E-38 T 12-10-2018 IPR008978 HSP20-like chaperone NPD12_1017 2807f393d4f7e941e6261cc0372a88d8 146 SUPERFAMILY SSF49764 14 145 2.97E-38 T 12-10-2018 IPR008978 HSP20-like chaperone NPD12_1017 2807f393d4f7e941e6261cc0372a88d8 146 Pfam PF00011 Hsp20/alpha crystallin family 45 146 6.6E-26 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain NPD12_1745 8b065da637a40e2e843c44a99b41ea4b 356 SUPERFAMILY SSF51726 7 348 3.66E-59 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_1745 8b065da637a40e2e843c44a99b41ea4b 356 Gene3D G3DSA:3.20.20.210 2 346 2.6E-82 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_1745 8b065da637a40e2e843c44a99b41ea4b 356 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 346 2.1E-72 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 NPD12_2952 133a287fd68db168fbf490779e710329 198 Pfam PF02698 DUF218 domain 44 166 9.1E-31 T 12-10-2018 IPR003848 Domain of unknown function DUF218 NPD12_2952 133a287fd68db168fbf490779e710329 198 Gene3D G3DSA:3.40.50.620 78 165 4.0E-7 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2653 7f84e783486d929630c8a07166456f22 184 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 182 1.3E-51 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase NPD12_2653 7f84e783486d929630c8a07166456f22 184 SUPERFAMILY SSF100950 3 182 2.37E-44 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_2653 7f84e783486d929630c8a07166456f22 184 PIRSF PIRSF006806 1 183 7.8E-48 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase NPD12_2653 7f84e783486d929630c8a07166456f22 184 Gene3D G3DSA:3.40.50.10420 1 184 6.7E-54 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily NPD12_2653 7f84e783486d929630c8a07166456f22 184 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 182 2.6E-39 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase NPD12_1101 8947f8f2f676028c5dd8ee881562683d 239 Gene3D G3DSA:1.10.1760.20 24 232 8.7E-58 T 12-10-2018 NPD12_1101 8947f8f2f676028c5dd8ee881562683d 239 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 24 231 1.7E-85 T 12-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 NPD12_1101 8947f8f2f676028c5dd8ee881562683d 239 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 25 231 2.2E-57 T 12-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 NPD12_1101 8947f8f2f676028c5dd8ee881562683d 239 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 24 237 28.305 T 12-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 NPD12_2772 4219e984a496e03503e2eb1746d36ebb 320 SUPERFAMILY SSF64518 2 320 4.58E-62 T 12-10-2018 NPD12_2772 4219e984a496e03503e2eb1746d36ebb 320 Pfam PF00700 Bacterial flagellin C-terminal helical region 237 319 1.5E-9 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2772 4219e984a496e03503e2eb1746d36ebb 320 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 1.1E-21 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 NPD12_2772 4219e984a496e03503e2eb1746d36ebb 320 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 199 6.1E-43 T 12-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 NPD12_2772 4219e984a496e03503e2eb1746d36ebb 320 Gene3D G3DSA:1.20.1330.10 40 266 1.0E-41 T 12-10-2018 NPD12_571 af68588bf3d0296ee8565d56b4df296d 201 SUPERFAMILY SSF52317 4 187 7.64E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_571 af68588bf3d0296ee8565d56b4df296d 201 Gene3D G3DSA:3.40.50.880 1 201 6.2E-64 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_571 af68588bf3d0296ee8565d56b4df296d 201 Pfam PF01965 DJ-1/PfpI family 4 167 1.2E-23 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 NPD12_503 f4634ed01392d0a9777dafdbdb2ca584 44 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 8 44 2.1E-14 T 12-10-2018 IPR009229 Staphylococcal AgrD NPD12_2162 49029cb12d1d86e4a6075092c27279a5 353 SUPERFAMILY SSF51419 8 224 2.38E-27 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_2162 49029cb12d1d86e4a6075092c27279a5 353 Pfam PF01168 Alanine racemase, N-terminal domain 8 223 6.6E-18 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 NPD12_2162 49029cb12d1d86e4a6075092c27279a5 353 Gene3D G3DSA:3.20.20.10 11 222 4.9E-25 T 12-10-2018 IPR029066 PLP-binding barrel NPD12_1199 59d17f0938dea55cb08720493a44989c 465 Pfam PF01565 FAD binding domain 45 182 5.0E-43 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 NPD12_1199 59d17f0938dea55cb08720493a44989c 465 Gene3D G3DSA:3.30.43.10 1 97 2.1E-25 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 NPD12_1199 59d17f0938dea55cb08720493a44989c 465 Gene3D G3DSA:3.30.465.10 99 218 4.3E-45 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 NPD12_1199 59d17f0938dea55cb08720493a44989c 465 Gene3D G3DSA:3.30.70.2740 341 423 1.0E-14 T 12-10-2018 NPD12_1199 59d17f0938dea55cb08720493a44989c 465 SUPERFAMILY SSF55103 225 464 5.07E-59 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 NPD12_1199 59d17f0938dea55cb08720493a44989c 465 Gene3D G3DSA:1.10.45.10 424 464 2.1E-12 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 NPD12_1199 59d17f0938dea55cb08720493a44989c 465 Pfam PF02913 FAD linked oxidases, C-terminal domain 220 463 3.1E-66 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 NPD12_1199 59d17f0938dea55cb08720493a44989c 465 SUPERFAMILY SSF56176 10 220 6.07E-69 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 NPD12_2478 acd96104c23bc657760cf9f161fa520d 265 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 220 246 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 NPD12_2478 acd96104c23bc657760cf9f161fa520d 265 Pfam PF01148 Cytidylyltransferase family 4 261 2.7E-57 T 12-10-2018 NPD12_1613 cc8eb1687f7b83390ad0a1f243df0b52 358 Gene3D G3DSA:2.40.100.10 246 358 4.1E-33 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily NPD12_1613 cc8eb1687f7b83390ad0a1f243df0b52 358 Gene3D G3DSA:3.20.20.70 2 241 9.3E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_1613 cc8eb1687f7b83390ad0a1f243df0b52 358 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 356 3.3E-125 T 12-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic NPD12_1613 cc8eb1687f7b83390ad0a1f243df0b52 358 SUPERFAMILY SSF51445 3 238 9.58E-77 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily NPD12_1613 cc8eb1687f7b83390ad0a1f243df0b52 358 SUPERFAMILY SSF50891 257 356 5.69E-28 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily NPD12_1049 80f8336e8eb7698b2e828e3fabaac171 310 PIRSF PIRSF016838 1 310 5.3E-19 T 12-10-2018 IPR028349 Protein PafC NPD12_1049 80f8336e8eb7698b2e828e3fabaac171 310 SUPERFAMILY SSF46785 4 58 1.79E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1049 80f8336e8eb7698b2e828e3fabaac171 310 Gene3D G3DSA:1.10.10.10 2 59 5.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1049 80f8336e8eb7698b2e828e3fabaac171 310 Pfam PF08279 HTH domain 5 54 3.4E-10 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 NPD12_1049 80f8336e8eb7698b2e828e3fabaac171 310 Pfam PF13280 WYL domain 137 305 3.5E-32 T 12-10-2018 IPR026881 WYL domain NPD12_2085 ea7221e33134fd868a615d16be539328 524 Gene3D G3DSA:3.40.50.11970 46 175 2.3E-13 T 12-10-2018 NPD12_2085 ea7221e33134fd868a615d16be539328 524 TIGRFAM TIGR02806 clostrip: clostripain 54 524 9.6E-260 T 12-10-2018 IPR014173 Peptidase C11, Clostripain Clostridium species NPD12_2085 ea7221e33134fd868a615d16be539328 524 Pfam PF03415 Clostripain family 60 508 5.8E-96 T 12-10-2018 IPR005077 Peptidase C11, clostripain NPD12_2876 ea4db456d8632c098b697b091857b206 225 SUPERFAMILY SSF48295 38 106 8.37E-14 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 NPD12_2876 ea4db456d8632c098b697b091857b206 225 SUPERFAMILY SSF48295 95 182 3.71E-23 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 NPD12_2876 ea4db456d8632c098b697b091857b206 225 SUPERFAMILY SSF46689 3 53 5.97E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2876 ea4db456d8632c098b697b091857b206 225 Pfam PF13518 Helix-turn-helix domain 130 179 1.0E-15 T 12-10-2018 NPD12_2876 ea4db456d8632c098b697b091857b206 225 Pfam PF13518 Helix-turn-helix domain 10 55 6.9E-6 T 12-10-2018 NPD12_2523 bb6d9205792a5ed480b48eee1f5d2783 156 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 5 98 7.2E-10 T 12-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 NPD12_383 0c3bcb4d9efd0f7d310f6584ff84eab2 343 SUPERFAMILY SSF100950 89 337 4.47E-68 T 12-10-2018 IPR037171 NagB/RpiA transferase-like NPD12_383 0c3bcb4d9efd0f7d310f6584ff84eab2 343 SUPERFAMILY SSF46785 19 84 1.5E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_383 0c3bcb4d9efd0f7d310f6584ff84eab2 343 Pfam PF04198 Putative sugar-binding domain 90 338 1.1E-64 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 NPD12_383 0c3bcb4d9efd0f7d310f6584ff84eab2 343 Gene3D G3DSA:1.10.10.10 16 91 1.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_383 0c3bcb4d9efd0f7d310f6584ff84eab2 343 Gene3D G3DSA:3.40.50.1360 92 338 9.1E-76 T 12-10-2018 NPD12_1914 3e784d6a04e98d94e25f7dfcecc0993d 195 Pfam PF00929 Exonuclease 4 141 2.6E-10 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_1914 3e784d6a04e98d94e25f7dfcecc0993d 195 SMART SM00479 2 195 2.7E-4 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III NPD12_1914 3e784d6a04e98d94e25f7dfcecc0993d 195 Gene3D G3DSA:3.30.420.10 1 193 2.7E-28 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 NPD12_1914 3e784d6a04e98d94e25f7dfcecc0993d 195 SUPERFAMILY SSF53098 2 190 2.78E-25 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily NPD12_1427 11ef9318a778e10ffd72c7213031e607 69 SUPERFAMILY SSF140500 20 65 6.15E-9 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 NPD12_1427 11ef9318a778e10ffd72c7213031e607 69 Pfam PF09388 Spo0E like sporulation regulatory protein 27 64 1.1E-9 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 NPD12_834 18f43667a54787d8a3e29eb4663cf39f 272 SMART SM00481 4 69 1.3E-14 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal NPD12_834 18f43667a54787d8a3e29eb4663cf39f 272 Pfam PF02811 PHP domain 5 218 2.1E-10 T 12-10-2018 IPR004013 PHP domain GO:0003824 NPD12_834 18f43667a54787d8a3e29eb4663cf39f 272 SUPERFAMILY SSF89550 1 260 1.31E-43 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_834 18f43667a54787d8a3e29eb4663cf39f 272 Gene3D G3DSA:3.20.20.140 5 248 2.6E-59 T 12-10-2018 NPD12_834 18f43667a54787d8a3e29eb4663cf39f 272 Gene3D G3DSA:1.10.150.650 99 172 2.6E-59 T 12-10-2018 NPD12_1655 011cb8f473556271286898402347f005 254 Gene3D G3DSA:3.40.50.300 2 244 6.6E-67 T 12-10-2018 NPD12_1655 011cb8f473556271286898402347f005 254 Pfam PF00005 ABC transporter 24 172 9.7E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1655 011cb8f473556271286898402347f005 254 SMART SM00382 33 221 1.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1655 011cb8f473556271286898402347f005 254 SUPERFAMILY SSF52540 5 225 1.09E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_700 00d0a1b87d96e93e6f542ce672ac2472 617 Pfam PF13520 Amino acid permease 31 434 3.0E-36 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_700 00d0a1b87d96e93e6f542ce672ac2472 617 Gene3D G3DSA:1.20.1740.10 33 471 5.2E-22 T 12-10-2018 NPD12_758 c4432c2d4c4f08615874fd12f49ac5bb 48 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 38 8.8E-13 T 12-10-2018 IPR027601 Cys-rich peptide, Clo7bot family NPD12_1662 278f7a229c0db660b917fd2ddca4c5c0 240 Gene3D G3DSA:3.90.640.20 149 236 7.7E-17 T 12-10-2018 IPR037126 PdaC/RsiV-like superfamily NPD12_1662 278f7a229c0db660b917fd2ddca4c5c0 240 Gene3D G3DSA:3.30.565.40 52 147 1.6E-12 T 12-10-2018 NPD12_1662 278f7a229c0db660b917fd2ddca4c5c0 240 Pfam PF11738 Protein of unknown function (DUF3298) 151 222 1.3E-14 T 12-10-2018 IPR021729 Domain of unknown function DUF3298 NPD12_1026 6aff95880ac2a131262e025ebe2bfe64 264 Pfam PF12679 ABC-2 family transporter protein 7 221 2.5E-10 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_261 df0f22291f3776f2673f71a5db6f93cf 460 SMART SM00729 113 308 0.0074 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_261 df0f22291f3776f2673f71a5db6f93cf 460 SUPERFAMILY SSF102114 111 394 1.65E-52 T 12-10-2018 NPD12_261 df0f22291f3776f2673f71a5db6f93cf 460 Gene3D G3DSA:3.20.20.70 110 385 1.1E-38 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_261 df0f22291f3776f2673f71a5db6f93cf 460 Pfam PF04055 Radical SAM superfamily 118 247 5.5E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_261 df0f22291f3776f2673f71a5db6f93cf 460 Pfam PF13353 4Fe-4S single cluster domain 122 206 1.1E-6 T 12-10-2018 NPD12_524 719d8cd2496076eeb316a5b81eada5df 188 SUPERFAMILY SSF109604 12 176 6.28E-17 T 12-10-2018 NPD12_524 719d8cd2496076eeb316a5b81eada5df 188 Pfam PF01966 HD domain 21 106 1.2E-6 T 12-10-2018 IPR006674 HD domain NPD12_524 719d8cd2496076eeb316a5b81eada5df 188 Gene3D G3DSA:1.10.3210.10 1 162 1.3E-13 T 12-10-2018 NPD12_473 2a276d722708a3909e141e9410b3eca3 322 Gene3D G3DSA:1.10.10.60 215 320 2.1E-22 T 12-10-2018 NPD12_473 2a276d722708a3909e141e9410b3eca3 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 301 5.6E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_473 2a276d722708a3909e141e9410b3eca3 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 301 317 5.6E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_473 2a276d722708a3909e141e9410b3eca3 322 SMART SM00342 235 317 4.6E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_473 2a276d722708a3909e141e9410b3eca3 322 Pfam PF12833 Helix-turn-helix domain 240 318 7.7E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_473 2a276d722708a3909e141e9410b3eca3 322 SUPERFAMILY SSF46689 272 320 7.62E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 94 109 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 443 8.6E-132 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 Gene3D G3DSA:1.20.1740.10 62 452 7.5E-8 T 12-10-2018 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 PRINTS PR00175 Sodium/alanine symporter signature 412 432 8.1E-48 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 PRINTS PR00175 Sodium/alanine symporter signature 94 116 8.1E-48 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 PRINTS PR00175 Sodium/alanine symporter signature 211 230 8.1E-48 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 PRINTS PR00175 Sodium/alanine symporter signature 306 324 8.1E-48 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 PRINTS PR00175 Sodium/alanine symporter signature 183 201 8.1E-48 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 PRINTS PR00175 Sodium/alanine symporter signature 353 375 8.1E-48 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1295 7d13edb6ad4c158e05ee6d6e2f8ce036 458 Pfam PF01235 Sodium:alanine symporter family 55 446 1.8E-121 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1906 45277c1b3982a93b5f9da9f486113eb6 183 Gene3D G3DSA:3.90.1720.10 8 169 2.2E-7 T 12-10-2018 NPD12_1906 45277c1b3982a93b5f9da9f486113eb6 183 SUPERFAMILY SSF54001 9 169 1.18E-6 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_277 2e8801ccf0c90994811f655de9a21722 506 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 18 495 3.5E-191 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 NPD12_277 2e8801ccf0c90994811f655de9a21722 506 PIRSF PIRSF005690 5 506 1.2E-176 T 12-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 NPD12_519 d95206f3386e2fc76e4f756e48730a8b 188 SUPERFAMILY SSF53335 21 156 2.32E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_519 d95206f3386e2fc76e4f756e48730a8b 188 Gene3D G3DSA:3.40.50.150 2 188 7.7E-68 T 12-10-2018 NPD12_519 d95206f3386e2fc76e4f756e48730a8b 188 Pfam PF06962 Putative rRNA methylase 51 186 9.2E-54 T 12-10-2018 IPR010719 Putative rRNA methylase NPD12_1866 a8b83666697becc0a94ac079a892a25b 483 Pfam PF13786 Domain of unknown function (DUF4179) 56 142 2.4E-17 T 12-10-2018 IPR025436 Domain of unknown function DUF4179 NPD12_1866 a8b83666697becc0a94ac079a892a25b 483 Gene3D G3DSA:2.60.40.1630 84 233 5.7E-14 T 12-10-2018 NPD12_782 4ca8470e5577133ca94e5d82a35b334b 130 SUPERFAMILY SSF47413 1 65 5.9E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_782 4ca8470e5577133ca94e5d82a35b334b 130 Gene3D G3DSA:1.10.260.40 1 64 1.2E-24 T 12-10-2018 NPD12_782 4ca8470e5577133ca94e5d82a35b334b 130 SMART SM00530 6 61 1.3E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_782 4ca8470e5577133ca94e5d82a35b334b 130 Pfam PF01381 Helix-turn-helix 7 61 2.7E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_1775 d68675e848e28053d853afbdb3115c01 402 Gene3D G3DSA:3.40.50.12020 1 176 5.8E-61 T 12-10-2018 NPD12_1775 d68675e848e28053d853afbdb3115c01 402 Pfam PF06792 Uncharacterised protein family (UPF0261) 2 400 9.4E-167 T 12-10-2018 IPR008322 Uncharacterised protein family UPF0261 NPD12_1775 d68675e848e28053d853afbdb3115c01 402 PIRSF PIRSF033271 1 402 7.0E-149 T 12-10-2018 IPR008322 Uncharacterised protein family UPF0261 NPD12_1775 d68675e848e28053d853afbdb3115c01 402 Gene3D G3DSA:3.40.50.12030 183 402 1.1E-91 T 12-10-2018 NPD12_443 603e82dbe7a1d3aa29542a3ef33aca93 656 Pfam PF02687 FtsX-like permease family 90 182 2.2E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_443 603e82dbe7a1d3aa29542a3ef33aca93 656 PIRSF PIRSF018968 1 655 2.1E-105 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 NPD12_1769 c2c52df6d26d7c9bb88863a391587990 155 SMART SM00347 33 133 1.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1769 c2c52df6d26d7c9bb88863a391587990 155 Pfam PF01047 MarR family 42 97 7.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_1769 c2c52df6d26d7c9bb88863a391587990 155 Gene3D G3DSA:1.10.10.10 1 154 6.9E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1769 c2c52df6d26d7c9bb88863a391587990 155 SUPERFAMILY SSF46785 8 148 3.6E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_751 c926b9c0bbed953c841de0be88a94f34 70 Gene3D G3DSA:1.10.260.40 1 64 5.4E-25 T 12-10-2018 NPD12_751 c926b9c0bbed953c841de0be88a94f34 70 Pfam PF01381 Helix-turn-helix 5 59 5.3E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_751 c926b9c0bbed953c841de0be88a94f34 70 SMART SM00530 4 59 7.2E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_751 c926b9c0bbed953c841de0be88a94f34 70 SUPERFAMILY SSF47413 2 62 4.29E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_747 030027b368fa6abe693441b526df1007 98 Gene3D G3DSA:3.40.630.30 10 94 3.4E-6 T 12-10-2018 NPD12_747 030027b368fa6abe693441b526df1007 98 SUPERFAMILY SSF55729 34 93 2.31E-6 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_3282 542e13157a305bd956bd936a391dcd66 253 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_3282 542e13157a305bd956bd936a391dcd66 253 SMART SM00382 32 213 6.0E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_3282 542e13157a305bd956bd936a391dcd66 253 SUPERFAMILY SSF52540 5 218 8.83E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3282 542e13157a305bd956bd936a391dcd66 253 Pfam PF00005 ABC transporter 23 162 5.6E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_3282 542e13157a305bd956bd936a391dcd66 253 Gene3D G3DSA:3.40.50.300 4 245 9.0E-66 T 12-10-2018 NPD12_2140 f091837b6ddab704b848184798588479 370 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 9 367 5.4E-52 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 NPD12_2140 f091837b6ddab704b848184798588479 370 Gene3D G3DSA:3.30.300.210 221 368 4.4E-17 T 12-10-2018 IPR038501 Spore germination GerAC superfamily NPD12_2140 f091837b6ddab704b848184798588479 370 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 205 366 2.1E-26 T 12-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 NPD12_2521 a487ab294a172f8746b487b3df9dafbc 295 Pfam PF01925 Sulfite exporter TauE/SafE 3 148 1.4E-11 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_2521 a487ab294a172f8746b487b3df9dafbc 295 Pfam PF01925 Sulfite exporter TauE/SafE 172 285 2.5E-8 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_2143 dee3b74bf80e04900eecec678972aa91 110 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 38 88 1.4E-10 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 NPD12_2143 dee3b74bf80e04900eecec678972aa91 110 Gene3D G3DSA:1.20.1290.10 8 109 5.9E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 NPD12_2143 dee3b74bf80e04900eecec678972aa91 110 TIGRFAM TIGR04169 perox_w_seleSAM: alkylhydroperoxidase/carboxymuconolactone decarboxylase family protein 2 110 8.8E-64 T 12-10-2018 IPR026445 Alkylhydroperoxidase/carboxymuconolactone decarboxylase family NPD12_2143 dee3b74bf80e04900eecec678972aa91 110 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 99 1.3E-18 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 NPD12_2143 dee3b74bf80e04900eecec678972aa91 110 SUPERFAMILY SSF69118 13 101 2.22E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 NPD12_946 c7017cf4479a4eccc25e1fee46ec8382 178 TIGRFAM TIGR03209 P21_Cbot: transcriptional regulator BotR, P-21 18 159 2.6E-72 T 12-10-2018 IPR017622 Transcription regulator, P21/BotR , Clostridium toxin-associated NPD12_946 c7017cf4479a4eccc25e1fee46ec8382 178 Pfam PF08281 Sigma-70, region 4 118 168 1.8E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 NPD12_946 c7017cf4479a4eccc25e1fee46ec8382 178 Gene3D G3DSA:1.10.10.10 115 176 9.7E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_946 c7017cf4479a4eccc25e1fee46ec8382 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 169 3.2E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 NPD12_946 c7017cf4479a4eccc25e1fee46ec8382 178 SUPERFAMILY SSF88659 113 175 1.18E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like NPD12_815 106c590d5cfff1acf5df6ef0955a2050 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 60 1.8E-5 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain NPD12_815 106c590d5cfff1acf5df6ef0955a2050 102 SUPERFAMILY SSF54909 8 84 5.37E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel NPD12_815 106c590d5cfff1acf5df6ef0955a2050 102 Gene3D G3DSA:3.30.70.100 3 77 1.1E-14 T 12-10-2018 NPD12_591 3f91b24d8e287c086e59222498a55a60 588 Pfam PF03553 Na+/H+ antiporter family 19 199 2.5E-6 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 NPD12_591 3f91b24d8e287c086e59222498a55a60 588 Pfam PF03553 Na+/H+ antiporter family 206 538 2.7E-61 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 NPD12_1532 eb290f840d2236b199af3772f93651fa 98 Gene3D G3DSA:1.20.1280.290 3 97 1.6E-8 T 12-10-2018 NPD12_1797 36c13a6215fddeb03dbbb4a7e7bb876c 216 SUPERFAMILY SSF52402 3 212 5.07E-67 T 12-10-2018 NPD12_1797 36c13a6215fddeb03dbbb4a7e7bb876c 216 PIRSF PIRSF006293 2 215 2.4E-77 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 NPD12_1797 36c13a6215fddeb03dbbb4a7e7bb876c 216 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 206 1.0E-82 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 NPD12_1797 36c13a6215fddeb03dbbb4a7e7bb876c 216 Gene3D G3DSA:3.40.50.620 2 215 9.0E-76 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_1797 36c13a6215fddeb03dbbb4a7e7bb876c 216 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 216 48.437 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 NPD12_1797 36c13a6215fddeb03dbbb4a7e7bb876c 216 Pfam PF06508 Queuosine biosynthesis protein QueC 5 212 1.4E-85 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 NPD12_1093 dd94987c672317fd7406d5cc237a5858 94 Pfam PF00583 Acetyltransferase (GNAT) family 14 67 3.6E-13 T 12-10-2018 IPR000182 GNAT domain NPD12_1093 dd94987c672317fd7406d5cc237a5858 94 Gene3D G3DSA:3.40.630.30 1 94 3.5E-23 T 12-10-2018 NPD12_1093 dd94987c672317fd7406d5cc237a5858 94 SUPERFAMILY SSF55729 9 94 4.12E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1103 97da6dfa826815c2048579baf72df775 228 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 12 190 2.5E-34 T 12-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 NPD12_1103 97da6dfa826815c2048579baf72df775 228 Pfam PF02361 Cobalt transport protein 18 194 1.8E-16 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component NPD12_1179 7c641eb09e6dfdd130deab45e208a06a 306 Gene3D G3DSA:3.30.1380.10 96 231 3.0E-61 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_1179 7c641eb09e6dfdd130deab45e208a06a 306 Gene3D G3DSA:3.30.200.180 85 304 3.0E-61 T 12-10-2018 NPD12_1179 7c641eb09e6dfdd130deab45e208a06a 306 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 120 233 1.1E-28 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 NPD12_1179 7c641eb09e6dfdd130deab45e208a06a 306 SUPERFAMILY SSF55166 110 242 1.1E-29 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_442 c45fdcfb55293e253ec71dfa0304030b 256 Gene3D G3DSA:3.40.50.300 1 248 1.4E-64 T 12-10-2018 NPD12_442 c45fdcfb55293e253ec71dfa0304030b 256 Pfam PF00005 ABC transporter 25 173 2.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_442 c45fdcfb55293e253ec71dfa0304030b 256 SMART SM00382 34 221 7.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_442 c45fdcfb55293e253ec71dfa0304030b 256 SUPERFAMILY SSF52540 3 224 3.38E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_222 fd4a443b1ce84befb1f34f755846ac9a 203 Pfam PF08876 Domain of unknown function (DUF1836) 26 129 5.4E-25 T 12-10-2018 IPR014975 Protein of unknown function DUF1836 NPD12_2417 cfdfb2a55f3c232bed0e44738eff925e 169 SUPERFAMILY SSF53335 2 109 1.25E-11 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2417 cfdfb2a55f3c232bed0e44738eff925e 169 Gene3D G3DSA:3.40.50.150 1 121 6.0E-6 T 12-10-2018 NPD12_248 4691a6c8c2956da8fd5ad1990d7cde55 241 PRINTS PR01837 MgtC/SapB protein signature 74 96 3.1E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 NPD12_248 4691a6c8c2956da8fd5ad1990d7cde55 241 PRINTS PR01837 MgtC/SapB protein signature 101 125 3.1E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 NPD12_248 4691a6c8c2956da8fd5ad1990d7cde55 241 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.1E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 NPD12_248 4691a6c8c2956da8fd5ad1990d7cde55 241 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.1E-41 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 NPD12_248 4691a6c8c2956da8fd5ad1990d7cde55 241 Pfam PF02308 MgtC family 10 147 5.5E-39 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 NPD12_2607 90a07993bfd358b54324fa1ba5b0b595 85 Pfam PF06949 Protein of unknown function (DUF1292) 13 81 8.9E-17 T 12-10-2018 IPR009711 Uncharacterised protein family UPF0473 NPD12_2607 90a07993bfd358b54324fa1ba5b0b595 85 Hamap MF_01448 UPF0473 protein . 4 83 14.231 T 12-10-2018 IPR009711 Uncharacterised protein family UPF0473 NPD12_1610 f0ed76af8d7d5307244ab8d6ebf1dc2f 281 Pfam PF01380 SIS domain 126 254 1.1E-25 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_1610 f0ed76af8d7d5307244ab8d6ebf1dc2f 281 SUPERFAMILY SSF53697 93 269 2.36E-44 T 12-10-2018 NPD12_1610 f0ed76af8d7d5307244ab8d6ebf1dc2f 281 Gene3D G3DSA:3.40.50.10490 93 279 2.3E-50 T 12-10-2018 NPD12_1610 f0ed76af8d7d5307244ab8d6ebf1dc2f 281 Gene3D G3DSA:1.10.10.10 1 75 3.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_1610 f0ed76af8d7d5307244ab8d6ebf1dc2f 281 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 73 5.6E-17 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_1610 f0ed76af8d7d5307244ab8d6ebf1dc2f 281 SUPERFAMILY SSF46689 1 74 9.5E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3076 b9df0187a9d3aba9da7c409d247e2378 144 SMART SM00530 6 62 3.7E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3076 b9df0187a9d3aba9da7c409d247e2378 144 SUPERFAMILY SSF47413 7 69 1.85E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3076 b9df0187a9d3aba9da7c409d247e2378 144 Pfam PF01381 Helix-turn-helix 9 62 4.0E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_3076 b9df0187a9d3aba9da7c409d247e2378 144 Gene3D G3DSA:1.10.260.40 3 71 2.0E-19 T 12-10-2018 NPD12_427 b11185581ff8088a3a40a76ab5045e52 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 2.5E-17 T 12-10-2018 IPR012452 Protein of unknown function DUF1657 NPD12_3428 96bc6802d35434a1699c8073506b350a 244 Pfam PF09335 SNARE associated Golgi protein 84 202 2.5E-28 T 12-10-2018 IPR032816 SNARE associated Golgi protein NPD12_1312 ba9652b09070da0c182dc6205f51e33d 145 SUPERFAMILY SSF54631 1 130 2.15E-29 T 12-10-2018 NPD12_1312 ba9652b09070da0c182dc6205f51e33d 145 Pfam PF00571 CBS domain 77 127 6.3E-5 T 12-10-2018 IPR000644 CBS domain NPD12_1312 ba9652b09070da0c182dc6205f51e33d 145 Pfam PF00571 CBS domain 13 59 2.8E-9 T 12-10-2018 IPR000644 CBS domain NPD12_1312 ba9652b09070da0c182dc6205f51e33d 145 SMART SM00116 12 60 0.0053 T 12-10-2018 IPR000644 CBS domain NPD12_1312 ba9652b09070da0c182dc6205f51e33d 145 Gene3D G3DSA:3.10.580.10 1 145 7.1E-45 T 12-10-2018 NPD12_1713 731b4c6f0c573d75e4e1ec753c1b3245 116 Pfam PF06947 Protein of unknown function (DUF1290) 21 106 3.4E-38 T 12-10-2018 IPR009709 Protein of unknown function DUF1290 NPD12_1713 731b4c6f0c573d75e4e1ec753c1b3245 116 PIRSF PIRSF018579 1 112 5.5E-47 T 12-10-2018 IPR009709 Protein of unknown function DUF1290 NPD12_3357 d4eb725b75251e15a6915fcecc3d459a 110 Pfam PF02635 DsrE/DsrF-like family 1 86 3.5E-7 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein NPD12_3357 d4eb725b75251e15a6915fcecc3d459a 110 SUPERFAMILY SSF75169 1 109 5.38E-17 T 12-10-2018 IPR027396 DsrEFH-like NPD12_3021 49c86dc69d6962066108d6e07a2b487e 504 Pfam PF07556 Protein of unknown function (DUF1538) 271 482 1.1E-69 T 12-10-2018 IPR011435 Protein of unknown function DUF1538 NPD12_3021 49c86dc69d6962066108d6e07a2b487e 504 Pfam PF07556 Protein of unknown function (DUF1538) 18 228 4.6E-60 T 12-10-2018 IPR011435 Protein of unknown function DUF1538 NPD12_2070 de0d6a5f69639a0ade8dbc11dc1eefbd 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 1.1E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site NPD12_2070 de0d6a5f69639a0ade8dbc11dc1eefbd 146 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 24 8.8E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site NPD12_952 3a758ff5cf365bc31144beac355702e0 153 Gene3D G3DSA:3.40.50.450 3 153 2.7E-55 T 12-10-2018 NPD12_952 3a758ff5cf365bc31144beac355702e0 153 SUPERFAMILY SSF52309 3 136 3.89E-17 T 12-10-2018 NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 SMART SM00347 22 122 5.3E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 Gene3D G3DSA:1.10.10.10 4 138 3.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 1.8E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 1.8E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 1.8E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 1.8E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 Pfam PF01047 MarR family 30 85 8.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 NPD12_2852 5c8cbff044662e4e79daf2e302f63056 139 SUPERFAMILY SSF46785 27 137 2.46E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_1320 60534454380a138c9cf057fa8026614c 442 Pfam PF06245 Protein of unknown function (DUF1015) 4 440 1.2E-135 T 12-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 NPD12_1320 60534454380a138c9cf057fa8026614c 442 PIRSF PIRSF033563 1 442 2.2E-140 T 12-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 NPD12_587 28dc3c9c11b0d5c380aef4b9c5ff5988 452 Gene3D G3DSA:3.20.20.70 39 372 2.4E-71 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_587 28dc3c9c11b0d5c380aef4b9c5ff5988 452 SUPERFAMILY SSF51569 41 342 3.85E-57 T 12-10-2018 NPD12_587 28dc3c9c11b0d5c380aef4b9c5ff5988 452 Pfam PF00682 HMGL-like 49 324 5.0E-27 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 NPD12_2379 9cea6d65521e90f4a3db8a6318c35705 90 SUPERFAMILY SSF46689 1 89 4.12E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2379 9cea6d65521e90f4a3db8a6318c35705 90 Pfam PF08765 Mor transcription activator family 16 88 5.3E-6 T 12-10-2018 IPR014875 Mor transcription activator NPD12_2699 5b359aac976ef3e951ee0984fb8f0251 135 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 13 82 1.9E-17 T 12-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 NPD12_2699 5b359aac976ef3e951ee0984fb8f0251 135 Pfam PF04347 Flagellar biosynthesis protein, FliO 30 99 5.4E-9 T 12-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 NPD12_2387 f1056ab7c5a00a7ab8156dfd2742925f 89 Pfam PF07659 Domain of Unknown Function (DUF1599) 22 85 8.3E-19 T 12-10-2018 IPR011630 Clostridium phage phiCTP1, Gp74 NPD12_1524 3e0fbfd928ce94ae895c57bcb72cbbc3 242 Gene3D G3DSA:3.30.240.20 169 229 2.3E-20 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily NPD12_1524 3e0fbfd928ce94ae895c57bcb72cbbc3 242 Pfam PF04239 Protein of unknown function (DUF421) 88 204 5.7E-36 T 12-10-2018 IPR007353 Protein of unknown function DUF421 NPD12_1524 3e0fbfd928ce94ae895c57bcb72cbbc3 242 Gene3D G3DSA:3.30.240.20 81 154 1.3E-23 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily NPD12_2598 6f93c9dc51b3861eb6024d0cd7deb681 267 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 19 226 8.0E-25 T 12-10-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 NPD12_2598 6f93c9dc51b3861eb6024d0cd7deb681 267 Pfam PF03837 RecT family 34 239 3.4E-43 T 12-10-2018 IPR018330 RecT family GO:0003677|GO:0006259 NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 SUPERFAMILY SSF89082 164 251 3.01E-29 T 12-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 Pfam PF13411 MerR HTH family regulatory protein 3 71 2.3E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 Gene3D G3DSA:1.10.1660.10 2 144 3.4E-46 T 12-10-2018 NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 Gene3D G3DSA:1.10.490.50 164 253 1.3E-27 T 12-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 7.8E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 7.8E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 7.8E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 Pfam PF07739 TipAS antibiotic-recognition domain 135 249 6.6E-39 T 12-10-2018 IPR012925 TipAS antibiotic-recognition domain NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 SMART SM00422 3 72 2.4E-28 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 NPD12_1097 46e650e87c6d7eb92d6915db2c2f5e9c 255 SUPERFAMILY SSF46955 3 115 8.42E-29 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_548 4a2888b82ae148ab3637669525cd117d 503 SUPERFAMILY SSF82171 290 364 6.28E-5 T 12-10-2018 NPD12_548 4a2888b82ae148ab3637669525cd117d 503 Pfam PF16472 Domain of unknown function (DUF5050) 327 392 2.0E-8 T 12-10-2018 IPR032485 Domain of unknown function DUF5050 NPD12_548 4a2888b82ae148ab3637669525cd117d 503 Gene3D G3DSA:3.10.620.30 115 267 1.8E-9 T 12-10-2018 NPD12_548 4a2888b82ae148ab3637669525cd117d 503 SUPERFAMILY SSF54001 116 313 1.5E-14 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_2094 44d530147a79d7afbf5d1fc53143af65 283 Pfam PF12679 ABC-2 family transporter protein 2 280 1.6E-10 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_2834 3f90f105493ea1fa650573a98ba2978a 55 Pfam PF13451 Probable zinc-ribbon domain 3 48 4.9E-26 T 12-10-2018 IPR025306 Probable zinc-binding domain NPD12_1299 47cc4a2b7aa36d9fb1f889aaf1bdf715 325 Pfam PF11185 Protein of unknown function (DUF2971) 124 242 4.1E-9 T 12-10-2018 IPR021352 Protein of unknown function DUF2971 NPD12_2509 66cdbb27c0730c3b96b672846b3f38dc 332 Gene3D G3DSA:3.40.50.10950 9 329 3.8E-142 T 12-10-2018 NPD12_2509 66cdbb27c0730c3b96b672846b3f38dc 332 Gene3D G3DSA:3.40.50.10750 142 302 3.8E-142 T 12-10-2018 NPD12_2509 66cdbb27c0730c3b96b672846b3f38dc 332 PIRSF PIRSF000428 1 332 6.5E-116 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_2509 66cdbb27c0730c3b96b672846b3f38dc 332 SUPERFAMILY SSF53659 1 329 1.69E-104 T 12-10-2018 NPD12_2509 66cdbb27c0730c3b96b672846b3f38dc 332 Pfam PF01515 Phosphate acetyl/butaryl transferase 3 326 8.8E-137 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_2509 66cdbb27c0730c3b96b672846b3f38dc 332 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 326 2.5E-125 T 12-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 NPD12_1765 671345024fe80c43405d85ee7fb21636 315 Gene3D G3DSA:1.50.10.150 5 302 2.4E-37 T 12-10-2018 IPR038665 Voltage-dependent anion channel superfamily NPD12_1765 671345024fe80c43405d85ee7fb21636 315 Pfam PF03595 Voltage-dependent anion channel 14 297 4.7E-30 T 12-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 NPD12_829 94ecbc70a80f709b3ec733c29d853e46 1176 SUPERFAMILY SSF52540 52 439 2.52E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_628 cbc5a0d90d6a3c5ad777ae27e58eeb69 146 Pfam PF12821 Threonine/Serine exporter, ThrE 4 131 1.3E-38 T 12-10-2018 IPR024528 Threonine/Serine exporter, ThrE NPD12_1645 7fcabdf4dccb05c509c3d7f64b084ef3 391 Pfam PF12698 ABC-2 family transporter protein 20 377 7.7E-22 T 12-10-2018 NPD12_1964 4c6393eb49e19ff7f6c2b6712cf77a56 429 Gene3D G3DSA:3.90.226.30 6 421 2.7E-138 T 12-10-2018 NPD12_1964 4c6393eb49e19ff7f6c2b6712cf77a56 429 Pfam PF09861 Domain of unknown function (DUF2088) 8 204 1.7E-76 T 12-10-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 NPD12_1964 4c6393eb49e19ff7f6c2b6712cf77a56 429 Gene3D G3DSA:3.40.50.11440 34 275 2.7E-138 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 Pfam PF13396 Phospholipase_D-nuclease N-terminal 14 55 6.2E-8 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 Gene3D G3DSA:3.30.870.10 100 290 2.8E-40 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 SUPERFAMILY SSF56024 257 460 2.92E-47 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 SMART SM00155 389 416 0.0013 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 SMART SM00155 206 233 1.1E-6 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 SUPERFAMILY SSF56024 83 305 4.08E-50 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 PIRSF PIRSF000850 360 450 0.41 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 PIRSF PIRSF000850 288 363 0.0071 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 PIRSF PIRSF000850 80 177 6.9 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 Gene3D G3DSA:3.30.870.10 291 447 1.1E-28 T 12-10-2018 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 Hamap MF_01916 Cardiolipin synthase. 7 476 42.538 T 12-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 Pfam PF13091 PLD-like domain 121 252 1.7E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 Pfam PF13091 PLD-like domain 317 442 9.6E-30 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 NPD12_2722 881547eb55704ec84bc3e1b40a089bfe 476 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 3 476 4.9E-147 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 NPD12_2202 52203d007d24a12991fbd203e01999cb 74 Gene3D G3DSA:1.10.287.950 1 72 1.2E-23 T 12-10-2018 NPD12_2202 52203d007d24a12991fbd203e01999cb 74 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 18 72 3.7E-18 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 NPD12_2202 52203d007d24a12991fbd203e01999cb 74 SUPERFAMILY SSF58104 7 71 1.31E-23 T 12-10-2018 NPD12_1280 d58aa78f1800e1d05a0739d82ef448b2 270 Gene3D G3DSA:3.40.190.10 118 220 3.8E-101 T 12-10-2018 NPD12_1280 d58aa78f1800e1d05a0739d82ef448b2 270 Pfam PF03180 NLPA lipoprotein 37 269 1.4E-96 T 12-10-2018 IPR004872 Lipoprotein NlpA family NPD12_1280 d58aa78f1800e1d05a0739d82ef448b2 270 Gene3D G3DSA:3.40.190.10 39 267 3.8E-101 T 12-10-2018 NPD12_1280 d58aa78f1800e1d05a0739d82ef448b2 270 PIRSF PIRSF002854 1 270 1.3E-109 T 12-10-2018 IPR004872 Lipoprotein NlpA family NPD12_1280 d58aa78f1800e1d05a0739d82ef448b2 270 SUPERFAMILY SSF53850 36 269 2.61E-85 T 12-10-2018 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 SUPERFAMILY SSF46604 88 132 6.02E-8 T 12-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 131 1.5E-13 T 12-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 130 17.638 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 83 5.5E-19 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 SUPERFAMILY SSF51344 4 84 4.58E-19 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 11 82 2.0E-9 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 130 3.6E-26 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 Gene3D G3DSA:2.60.15.10 1 83 3.2E-20 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 NPD12_312 e6b3118611c293df1ceda139dd8bc941 133 Gene3D G3DSA:1.20.5.440 91 133 1.3E-13 T 12-10-2018 NPD12_1309 a057efbdd1f096fa5c0cb2801c64b95a 184 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 138 166 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 NPD12_1309 a057efbdd1f096fa5c0cb2801c64b95a 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 162 5.6E-9 T 12-10-2018 IPR001451 Hexapeptide repeat NPD12_1309 a057efbdd1f096fa5c0cb2801c64b95a 184 Gene3D G3DSA:2.160.10.10 2 183 1.3E-71 T 12-10-2018 NPD12_1309 a057efbdd1f096fa5c0cb2801c64b95a 184 SUPERFAMILY SSF51161 5 183 2.08E-54 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily NPD12_1309 a057efbdd1f096fa5c0cb2801c64b95a 184 SMART SM01266 7 58 1.7E-19 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 NPD12_1309 a057efbdd1f096fa5c0cb2801c64b95a 184 Pfam PF12464 Maltose acetyltransferase 9 57 5.6E-16 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 NPD12_1918 a56e13903e6b7eaae0cd6728717afc8e 459 Pfam PF00854 POT family 241 423 2.4E-29 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_1918 a56e13903e6b7eaae0cd6728717afc8e 459 Pfam PF00854 POT family 86 209 4.0E-12 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 NPD12_1918 a56e13903e6b7eaae0cd6728717afc8e 459 Gene3D G3DSA:1.20.1250.20 235 459 1.3E-50 T 12-10-2018 NPD12_1918 a56e13903e6b7eaae0cd6728717afc8e 459 Gene3D G3DSA:1.20.1250.20 1 234 2.4E-55 T 12-10-2018 NPD12_1918 a56e13903e6b7eaae0cd6728717afc8e 459 SUPERFAMILY SSF103473 8 452 5.89E-40 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_1918 a56e13903e6b7eaae0cd6728717afc8e 459 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 8 172 2.3E-38 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 NPD12_1451 505ac7a1254621c8ea9f236988735a1b 107 Pfam PF04723 Glycine reductase complex selenoprotein A 1 99 2.3E-48 T 12-10-2018 IPR006812 Glycine reductase complex selenoprotein A GO:0030699|GO:0030700|GO:0050485|GO:0055114 NPD12_1451 505ac7a1254621c8ea9f236988735a1b 107 PIRSF PIRSF000181 1 107 1.6E-53 T 12-10-2018 IPR006812 Glycine reductase complex selenoprotein A GO:0030699|GO:0030700|GO:0050485|GO:0055114 NPD12_3031 fd412af8a99a4d240b7c366fae330a23 579 Pfam PF12571 Phage tail-collar fibre protein 2 149 4.5E-58 T 12-10-2018 IPR022225 Phage tail fibre protein NPD12_3031 fd412af8a99a4d240b7c366fae330a23 579 SUPERFAMILY SSF50998 258 564 3.3E-6 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily NPD12_2099 78d1788ed25e5a681ce7decf97035c5c 146 SUPERFAMILY SSF55729 1 140 3.31E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2099 78d1788ed25e5a681ce7decf97035c5c 146 Gene3D G3DSA:3.40.630.30 43 146 2.6E-28 T 12-10-2018 NPD12_2099 78d1788ed25e5a681ce7decf97035c5c 146 Gene3D G3DSA:1.10.287.900 1 39 5.0E-7 T 12-10-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117|MetaCyc: PWY-6922 NPD12_2099 78d1788ed25e5a681ce7decf97035c5c 146 Pfam PF00583 Acetyltransferase (GNAT) family 33 128 8.6E-16 T 12-10-2018 IPR000182 GNAT domain NPD12_3664 96bcdc8e42dd5fdc33cdbf721c6c20fb 405 Gene3D G3DSA:3.40.50.1100 51 147 8.6E-124 T 12-10-2018 NPD12_3664 96bcdc8e42dd5fdc33cdbf721c6c20fb 405 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 22 400 3.4E-146 T 12-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 NPD12_3664 96bcdc8e42dd5fdc33cdbf721c6c20fb 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 304 4.1E-84 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme NPD12_3664 96bcdc8e42dd5fdc33cdbf721c6c20fb 405 SUPERFAMILY SSF55021 327 399 1.14E-5 T 12-10-2018 NPD12_3664 96bcdc8e42dd5fdc33cdbf721c6c20fb 405 SUPERFAMILY SSF53686 5 314 5.24E-104 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme NPD12_3664 96bcdc8e42dd5fdc33cdbf721c6c20fb 405 Gene3D G3DSA:3.40.50.1100 8 309 8.6E-124 T 12-10-2018 NPD12_3664 96bcdc8e42dd5fdc33cdbf721c6c20fb 405 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 43 56 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 NPD12_1090 ff9ccdea34559c3de52fe056daed9489 181 Gene3D G3DSA:1.10.1760.20 1 180 1.3E-55 T 12-10-2018 NPD12_1090 ff9ccdea34559c3de52fe056daed9489 181 Pfam PF02632 BioY family 32 173 4.4E-39 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 NPD12_1090 ff9ccdea34559c3de52fe056daed9489 181 PIRSF PIRSF016661 1 181 6.4E-49 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 NPD12_496 c47acd9dba3884790f78d2d85eef8af1 44 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 6 42 2.0E-13 T 12-10-2018 IPR009229 Staphylococcal AgrD NPD12_1024 4744d6d3fb1a9b0126d506504d185c8b 184 SMART SM00903 11 145 3.4E-8 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 NPD12_1024 4744d6d3fb1a9b0126d506504d185c8b 184 SUPERFAMILY SSF50475 9 171 1.57E-32 T 12-10-2018 NPD12_1024 4744d6d3fb1a9b0126d506504d185c8b 184 Gene3D G3DSA:2.30.110.10 2 184 1.3E-55 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 NPD12_1024 4744d6d3fb1a9b0126d506504d185c8b 184 Pfam PF01613 Flavin reductase like domain 15 165 1.7E-16 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 NPD12_3696 0840941dea1eda9e6a75316419c19d63 258 Pfam PF03309 Type III pantothenate kinase 2 205 1.9E-74 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 NPD12_3696 0840941dea1eda9e6a75316419c19d63 258 Gene3D G3DSA:3.30.420.40 89 258 6.1E-58 T 12-10-2018 NPD12_3696 0840941dea1eda9e6a75316419c19d63 258 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 258 36.994 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 NPD12_3696 0840941dea1eda9e6a75316419c19d63 258 SUPERFAMILY SSF53067 123 257 6.26E-35 T 12-10-2018 NPD12_3696 0840941dea1eda9e6a75316419c19d63 258 SUPERFAMILY SSF53067 1 121 6.47E-40 T 12-10-2018 NPD12_3696 0840941dea1eda9e6a75316419c19d63 258 Gene3D G3DSA:3.30.420.40 1 88 6.7E-35 T 12-10-2018 NPD12_3696 0840941dea1eda9e6a75316419c19d63 258 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 253 1.8E-75 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 NPD12_116 4a95c2b6bdb975bddee3a57c10937d8b 169 Pfam PF14584 Protein of unknown function (DUF4446) 15 162 1.7E-56 T 12-10-2018 IPR027981 Protein of unknown function DUF4446 NPD12_1589 e72b83c26c38ba69cbbc72da1d6b4965 215 SUPERFAMILY SSF64005 2 209 4.19E-47 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 NPD12_1589 e72b83c26c38ba69cbbc72da1d6b4965 215 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 3 209 1.4E-32 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 NPD12_1589 e72b83c26c38ba69cbbc72da1d6b4965 215 Gene3D G3DSA:3.40.1180.10 1 215 2.0E-46 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 NPD12_1589 e72b83c26c38ba69cbbc72da1d6b4965 215 Pfam PF01255 Putative undecaprenyl diphosphate synthase 10 211 3.1E-40 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 NPD12_2403 03ecad24413fd1f50acbe0257a359f4d 319 SUPERFAMILY SSF46689 268 318 2.78E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_2403 03ecad24413fd1f50acbe0257a359f4d 319 SMART SM00342 232 315 1.2E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2403 03ecad24413fd1f50acbe0257a359f4d 319 Pfam PF12833 Helix-turn-helix domain 241 316 1.0E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 NPD12_2403 03ecad24413fd1f50acbe0257a359f4d 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 315 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_2403 03ecad24413fd1f50acbe0257a359f4d 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 299 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 NPD12_2403 03ecad24413fd1f50acbe0257a359f4d 319 Gene3D G3DSA:1.10.10.60 213 317 3.0E-26 T 12-10-2018 NPD12_1095 b16979ad6972b84f6c738b0b79c3d417 185 SUPERFAMILY SSF52540 7 184 1.51E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1095 b16979ad6972b84f6c738b0b79c3d417 185 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 8 184 6.9E-58 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 NPD12_1095 b16979ad6972b84f6c738b0b79c3d417 185 PIRSF PIRSF006135 6 185 2.7E-56 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 NPD12_1095 b16979ad6972b84f6c738b0b79c3d417 185 Gene3D G3DSA:3.40.50.300 7 185 2.5E-58 T 12-10-2018 NPD12_204 eb3f425397a9387da0c0400c47e97116 247 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 5 244 63.159 T 12-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 NPD12_204 eb3f425397a9387da0c0400c47e97116 247 Pfam PF02146 Sir2 family 21 201 7.5E-52 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 NPD12_204 eb3f425397a9387da0c0400c47e97116 247 SUPERFAMILY SSF52467 3 246 1.47E-84 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily NPD12_204 eb3f425397a9387da0c0400c47e97116 247 Gene3D G3DSA:3.30.1600.10 30 171 1.2E-77 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily NPD12_204 eb3f425397a9387da0c0400c47e97116 247 Gene3D G3DSA:3.40.50.1220 12 242 1.2E-77 T 12-10-2018 NPD12_708 2e39f3b99603959c165961b03087818a 178 Pfam PF02417 Chromate transporter 5 170 3.3E-47 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 NPD12_2737 4688f19c9f26385fa732399270d763ae 225 Pfam PF02706 Chain length determinant protein 6 97 8.1E-15 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 NPD12_2737 4688f19c9f26385fa732399270d763ae 225 Pfam PF13807 G-rich domain on putative tyrosine kinase 155 197 4.1E-8 T 12-10-2018 IPR032807 Tyrosine kinase, G-rich domain NPD12_2809 1c51e7461a881ee8a5e4190c441dff96 78 Pfam PF02344 Myc leucine zipper domain 50 75 3.7E-5 T 12-10-2018 IPR003327 Leucine zipper, Myc GO:0003700|GO:0005634|GO:0006355 Reactome: R-HSA-1362277|Reactome: R-HSA-2122947|Reactome: R-HSA-2173796|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-4411364|Reactome: R-HSA-5687128|Reactome: R-HSA-5689880|Reactome: R-HSA-6785807|Reactome: R-HSA-69202|Reactome: R-HSA-69656|Reactome: R-HSA-8866911|Reactome: R-HSA-8951430|Reactome: R-HSA-9018519 NPD12_495 42877a322d6807f464dd85177629e567 229 Pfam PF04647 Accessory gene regulator B 8 197 1.2E-41 T 12-10-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 NPD12_495 42877a322d6807f464dd85177629e567 229 SMART SM00793 6 206 8.2E-23 T 12-10-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 NPD12_3522 a1d80ccf6e84e967d0fc1f2aea6271d4 133 SUPERFAMILY SSF46785 2 129 4.61E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_3522 a1d80ccf6e84e967d0fc1f2aea6271d4 133 Pfam PF02082 Transcriptional regulator 1 83 1.2E-27 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_3522 a1d80ccf6e84e967d0fc1f2aea6271d4 133 Gene3D G3DSA:1.10.10.10 1 132 1.0E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_3522 a1d80ccf6e84e967d0fc1f2aea6271d4 133 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 127 1.7E-40 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type NPD12_538 087ce85d6ef5d48a12c093aad7038015 362 Pfam PF04122 Putative cell wall binding repeat 2 246 346 2.8E-14 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_538 087ce85d6ef5d48a12c093aad7038015 362 Pfam PF04122 Putative cell wall binding repeat 2 34 122 1.7E-16 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_538 087ce85d6ef5d48a12c093aad7038015 362 Pfam PF04122 Putative cell wall binding repeat 2 144 230 1.1E-11 T 12-10-2018 IPR007253 Putative cell wall binding repeat 2 NPD12_538 087ce85d6ef5d48a12c093aad7038015 362 Gene3D G3DSA:3.40.50.12090 57 159 2.7E-5 T 12-10-2018 NPD12_1711 6bd2632b37ea141aecb0f78acba5e0fa 256 Pfam PF08478 POTRA domain, FtsQ-type 45 113 2.1E-17 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type NPD12_1711 6bd2632b37ea141aecb0f78acba5e0fa 256 Pfam PF03799 Cell division protein FtsQ 123 244 3.7E-7 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB NPD12_1711 6bd2632b37ea141aecb0f78acba5e0fa 256 Hamap MF_00912 Cell division protein DivIB [divIB]. 1 235 23.739 T 12-10-2018 IPR026580 Cell division protein DivIB NPD12_1711 6bd2632b37ea141aecb0f78acba5e0fa 256 Gene3D G3DSA:3.10.20.310 44 113 9.1E-7 T 12-10-2018 NPD12_636 78c3d4b1fa6237e195254d925c7f0332 79 Gene3D G3DSA:1.10.260.40 6 79 1.2E-11 T 12-10-2018 NPD12_636 78c3d4b1fa6237e195254d925c7f0332 79 SMART SM00530 6 62 1.5E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_636 78c3d4b1fa6237e195254d925c7f0332 79 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 8.9E-23 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_636 78c3d4b1fa6237e195254d925c7f0332 79 SUPERFAMILY SSF47413 2 70 7.32E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_3354 f2a9ccf1674304da8c779cc5d5806f51 83 Pfam PF11823 Protein of unknown function (DUF3343) 6 72 3.1E-22 T 12-10-2018 IPR021778 Domain of unknown function DUF3343 NPD12_2148 e6177df3f61015f0ff2b9723e6474d79 521 SUPERFAMILY SSF52540 296 518 1.22E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2148 e6177df3f61015f0ff2b9723e6474d79 521 SUPERFAMILY SSF48334 55 285 6.41E-7 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily NPD12_2148 e6177df3f61015f0ff2b9723e6474d79 521 SMART SM00533 49 320 0.0062 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 NPD12_2148 e6177df3f61015f0ff2b9723e6474d79 521 Gene3D G3DSA:3.40.50.300 296 520 4.5E-49 T 12-10-2018 NPD12_2148 e6177df3f61015f0ff2b9723e6474d79 521 SMART SM00534 329 515 1.0E-10 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_2148 e6177df3f61015f0ff2b9723e6474d79 521 Pfam PF00488 MutS domain V 333 517 1.6E-25 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 152 6.1E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 82 93 6.1E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 162 175 6.1E-15 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 387 3.1E-9 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 Gene3D G3DSA:3.40.710.10 23 323 1.7E-93 T 12-10-2018 NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 SUPERFAMILY SSF56601 8 299 9.5E-80 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 SMART SM00936 299 388 1.2E-11 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 NPD12_2012 5c8a68f6cb20df6054fdc963f6fbdb48 407 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 51 279 2.2E-76 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 NPD12_2434 f01c367446a2b09ec031b70697180715 56 Pfam PF02517 CAAX protease self-immunity 1 53 3.0E-9 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_1546 6c26fa797cd0f61e8a6b7a8a93dd5d43 420 SUPERFAMILY SSF53448 50 321 4.69E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_1546 6c26fa797cd0f61e8a6b7a8a93dd5d43 420 Gene3D G3DSA:3.90.550.10 37 274 1.0E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_1546 6c26fa797cd0f61e8a6b7a8a93dd5d43 420 Pfam PF13641 Glycosyltransferase like family 2 53 283 5.7E-37 T 12-10-2018 NPD12_805 001e44c300d6359e84686da1058d822e 243 Pfam PF12698 ABC-2 family transporter protein 14 233 3.1E-16 T 12-10-2018 NPD12_1865 4a6c949357e289fd9f357b8799ed4e04 155 SUPERFAMILY SSF88946 5 94 1.23E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_1865 4a6c949357e289fd9f357b8799ed4e04 155 Pfam PF04542 Sigma-70 region 2 43 91 1.6E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 NPD12_1865 4a6c949357e289fd9f357b8799ed4e04 155 Gene3D G3DSA:1.10.1740.10 4 90 1.1E-10 T 12-10-2018 NPD12_2242 2de14359ac28fe3b46a9dbdcac686ca4 532 TIGRFAM TIGR02518 EutH_ACDH: acetaldehyde dehydrogenase (acetylating) 5 529 6.8E-252 T 12-10-2018 IPR013357 Acetaldehyde dehydrogenase, acetylating NPD12_2242 2de14359ac28fe3b46a9dbdcac686ca4 532 Pfam PF00171 Aldehyde dehydrogenase family 22 274 1.3E-22 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 NPD12_2242 2de14359ac28fe3b46a9dbdcac686ca4 532 SUPERFAMILY SSF53720 11 448 2.49E-80 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 NPD12_2242 2de14359ac28fe3b46a9dbdcac686ca4 532 Gene3D G3DSA:3.40.309.10 223 405 1.0E-175 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 NPD12_2242 2de14359ac28fe3b46a9dbdcac686ca4 532 Gene3D G3DSA:3.40.605.10 15 443 1.0E-175 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 NPD12_1092 82090ed11df7d8477f471b5d445a73e0 105 Gene3D G3DSA:3.40.630.30 13 104 6.0E-14 T 12-10-2018 NPD12_1092 82090ed11df7d8477f471b5d445a73e0 105 SUPERFAMILY SSF55729 18 96 9.89E-10 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2801 86cd19474871f12c3e57fcbf33bfdc14 136 Pfam PF04138 GtrA-like protein 12 133 2.0E-10 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 NPD12_988 b26ecee5b547b9d3051e856860dacf4a 78 SUPERFAMILY SSF48295 5 55 2.51E-10 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 NPD12_988 b26ecee5b547b9d3051e856860dacf4a 78 Pfam PF01527 Transposase 4 52 6.7E-6 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 NPD12_723 617394df1c553a0fcebf25099e8a2b6f 229 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 125 203 1.5E-7 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF NPD12_2176 967bc133baca708b423300faa9e1090c 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 223 2.7E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_2176 967bc133baca708b423300faa9e1090c 228 Gene3D G3DSA:1.10.3720.10 1 226 1.4E-64 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2176 967bc133baca708b423300faa9e1090c 228 SUPERFAMILY SSF161098 12 208 1.83E-49 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_2176 967bc133baca708b423300faa9e1090c 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 117 5.3E-28 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 NPD12_1279 d9b3ec01b96044c9613cc0ff816206d4 213 SUPERFAMILY SSF161098 4 199 3.66E-44 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1279 d9b3ec01b96044c9613cc0ff816206d4 213 Gene3D G3DSA:1.10.3720.10 2 213 1.6E-47 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1279 d9b3ec01b96044c9613cc0ff816206d4 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 213 1.3E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1347 3fae5f69698033cfb05535c412f6da83 139 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 10 123 1.1E-26 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 NPD12_1347 3fae5f69698033cfb05535c412f6da83 139 SUPERFAMILY SSF54637 2 131 9.89E-35 T 12-10-2018 IPR029069 HotDog domain superfamily NPD12_1347 3fae5f69698033cfb05535c412f6da83 139 PIRSF PIRSF003230 2 139 3.5E-34 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 NPD12_1347 3fae5f69698033cfb05535c412f6da83 139 Gene3D G3DSA:3.10.129.10 5 138 5.3E-34 T 12-10-2018 NPD12_1347 3fae5f69698033cfb05535c412f6da83 139 Pfam PF13279 Thioesterase-like superfamily 13 117 4.6E-11 T 12-10-2018 NPD12_2659 0f4dd828069c15ea0914667f5eb976e8 332 Gene3D G3DSA:3.30.200.20 9 107 4.5E-6 T 12-10-2018 NPD12_2659 0f4dd828069c15ea0914667f5eb976e8 332 SUPERFAMILY SSF56112 19 292 2.55E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_2659 0f4dd828069c15ea0914667f5eb976e8 332 Pfam PF01636 Phosphotransferase enzyme family 33 240 6.0E-10 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase NPD12_2350 6b18efcc96aa7cb1d0e867866b3a6ed0 261 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 219 4.0E-25 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel NPD12_2350 6b18efcc96aa7cb1d0e867866b3a6ed0 261 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site NPD12_3455 e9cb1b1de8fdb9c88e39535e5900602e 187 Pfam PF07155 ECF-type riboflavin transporter, S component 11 179 1.5E-49 T 12-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 NPD12_3455 e9cb1b1de8fdb9c88e39535e5900602e 187 Gene3D G3DSA:1.10.1760.20 8 182 1.3E-46 T 12-10-2018 NPD12_910 cdaf3e12fe4559f42df919294b6351dd 208 Gene3D G3DSA:3.40.50.880 1 208 1.0E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_910 cdaf3e12fe4559f42df919294b6351dd 208 Pfam PF01965 DJ-1/PfpI family 5 167 1.1E-21 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 NPD12_910 cdaf3e12fe4559f42df919294b6351dd 208 SUPERFAMILY SSF52317 5 177 1.69E-27 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_1691 142b97e02e14a8c42be14ba326dc27d6 96 SUPERFAMILY SSF55486 8 89 1.14E-14 T 12-10-2018 NPD12_1691 142b97e02e14a8c42be14ba326dc27d6 96 Gene3D G3DSA:1.10.390.10 1 88 1.6E-19 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily NPD12_1691 142b97e02e14a8c42be14ba326dc27d6 96 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 5 88 5.7E-23 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 NPD12_3209 3da6fc0043e8c862239ea1afa6e9bd7a 352 Gene3D G3DSA:3.40.50.2000 182 335 1.8E-131 T 12-10-2018 NPD12_3209 3da6fc0043e8c862239ea1afa6e9bd7a 352 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 348 3.2E-117 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 NPD12_3209 3da6fc0043e8c862239ea1afa6e9bd7a 352 SUPERFAMILY SSF53756 1 350 1.32E-111 T 12-10-2018 NPD12_3209 3da6fc0043e8c862239ea1afa6e9bd7a 352 Gene3D G3DSA:3.40.50.2000 6 345 1.8E-131 T 12-10-2018 NPD12_3209 3da6fc0043e8c862239ea1afa6e9bd7a 352 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 350 1.6E-103 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 NPD12_1941 f9cd9688a969c7b427a279f8f783b396 66 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 45 59 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 NPD12_1941 f9cd9688a969c7b427a279f8f783b396 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 66 8.5E-26 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 NPD12_1941 f9cd9688a969c7b427a279f8f783b396 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 12-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 NPD12_1941 f9cd9688a969c7b427a279f8f783b396 66 Gene3D G3DSA:1.10.8.910 7 66 4.7E-23 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily NPD12_1490 81629b2f310a7031975b783a2aa1be54 189 Pfam PF06810 Phage minor structural protein GP20 23 149 8.5E-36 T 12-10-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069 NPD12_1433 747e6a70312381618c7d6de35c3c9ec6 230 Pfam PF12730 ABC-2 family transporter protein 26 186 1.3E-7 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_3510 54e5a8eeebe2f5a012ae0fa2f415f677 91 Gene3D G3DSA:1.10.10.60 48 90 7.9E-6 T 12-10-2018 NPD12_3510 54e5a8eeebe2f5a012ae0fa2f415f677 91 SUPERFAMILY SSF46689 3 88 7.88E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_3510 54e5a8eeebe2f5a012ae0fa2f415f677 91 Pfam PF08765 Mor transcription activator family 10 89 2.2E-8 T 12-10-2018 IPR014875 Mor transcription activator NPD12_863 2790a048c9db4040f1ac8402bc8db9e1 346 SUPERFAMILY SSF81345 16 341 4.32E-77 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_863 2790a048c9db4040f1ac8402bc8db9e1 346 Pfam PF01032 FecCD transport family 31 341 3.9E-85 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 NPD12_863 2790a048c9db4040f1ac8402bc8db9e1 346 Gene3D G3DSA:1.10.3470.10 18 346 5.9E-87 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_979 2a407fa90b8eb2866cf8714b0ef614c7 259 Pfam PF07155 ECF-type riboflavin transporter, S component 5 161 8.5E-11 T 12-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 NPD12_979 2a407fa90b8eb2866cf8714b0ef614c7 259 Gene3D G3DSA:1.10.1760.20 1 186 6.0E-20 T 12-10-2018 NPD12_3557 3f85e38458fc1800352369a5fa438170 120 PIRSF PIRSF033595 1 117 1.3E-39 T 12-10-2018 IPR017016 Uncharacterised conserved protein UCP033595 NPD12_1420 8a6f68801bad2b29823fed31f35f362d 354 SUPERFAMILY SSF82171 44 314 2.35E-15 T 12-10-2018 NPD12_1728 0c8f246929614c97036855884dc4a0d4 447 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 337 357 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 NPD12_1728 0c8f246929614c97036855884dc4a0d4 447 Pfam PF00860 Permease family 15 390 5.4E-101 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 NPD12_1728 0c8f246929614c97036855884dc4a0d4 447 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 417 1.6E-122 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 NPD12_3712 96cdb5b9fce2d1c42631856fdbe0ffdd 155 SUPERFAMILY SSF52980 18 153 6.44E-22 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 NPD12_3712 96cdb5b9fce2d1c42631856fdbe0ffdd 155 Pfam PF03838 Recombination protein U 41 139 1.0E-16 T 12-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 NPD12_3712 96cdb5b9fce2d1c42631856fdbe0ffdd 155 Gene3D G3DSA:3.40.1350.10 32 154 1.7E-16 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 NPD12_3808 3037248f55bd9428ea17df0e6751560e 203 Pfam PF04404 ERF superfamily 3 144 1.8E-13 T 12-10-2018 IPR007499 Essential recombination function protein NPD12_855 cbdc12397c48bf349f56346cc1a6a3e1 250 SUPERFAMILY SSF69318 25 210 1.31E-8 T 12-10-2018 NPD12_2298 1982059cb302a092e5a69650c81d847f 173 Pfam PF16107 Domain of unknown function (DUF4825) 45 144 6.4E-27 T 12-10-2018 IPR032250 Domain of unknown function DUF4825 NPD12_372 46811deaba2d20848e74aeffae1c9ed6 378 Pfam PF04294 VanW like protein 247 376 9.3E-50 T 12-10-2018 IPR007391 Vancomycin resistance VanW NPD12_372 46811deaba2d20848e74aeffae1c9ed6 378 Pfam PF12229 Putative peptidoglycan binding domain 94 208 1.6E-19 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain NPD12_2533 3af77e22717393097f2c67fcc6068280 175 Pfam PF03773 Predicted permease 41 169 2.2E-14 T 12-10-2018 IPR005524 Predicted permease DUF318 NPD12_1623 ca08bed6dd2989b9a9dd330cec9f81a5 266 Gene3D G3DSA:1.10.3720.10 57 264 3.9E-20 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1623 ca08bed6dd2989b9a9dd330cec9f81a5 266 SUPERFAMILY SSF161098 61 250 1.22E-24 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1623 ca08bed6dd2989b9a9dd330cec9f81a5 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 261 3.8E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_1118 340b6db3111b398cf3fcd817227c5bef 173 SUPERFAMILY SSF55469 2 167 7.2E-37 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_1118 340b6db3111b398cf3fcd817227c5bef 173 Pfam PF00881 Nitroreductase family 5 58 5.2E-11 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_1118 340b6db3111b398cf3fcd817227c5bef 173 Pfam PF00881 Nitroreductase family 67 149 1.7E-7 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 NPD12_1118 340b6db3111b398cf3fcd817227c5bef 173 Gene3D G3DSA:3.40.109.10 1 172 2.3E-45 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 NPD12_1830 a4f5678f28d891ac703c9881438ce6f6 198 Pfam PF08876 Domain of unknown function (DUF1836) 22 129 2.8E-31 T 12-10-2018 IPR014975 Protein of unknown function DUF1836 NPD12_954 ba47b2fca949d59828fbf2bb7eac9b45 252 Pfam PF13649 Methyltransferase domain 43 138 3.5E-17 T 12-10-2018 NPD12_954 ba47b2fca949d59828fbf2bb7eac9b45 252 SUPERFAMILY SSF53335 17 217 3.65E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_954 ba47b2fca949d59828fbf2bb7eac9b45 252 Gene3D G3DSA:3.40.50.150 30 252 5.8E-30 T 12-10-2018 NPD12_3673 dda0f8b0e07606980ccc7b6b6877b54d 347 ProSitePatterns PS00112 Phosphagen kinase active site signature. 156 162 - T 12-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 NPD12_3673 dda0f8b0e07606980ccc7b6b6877b54d 347 SUPERFAMILY SSF55931 9 257 2.44E-81 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 NPD12_3673 dda0f8b0e07606980ccc7b6b6877b54d 347 Hamap MF_00602 Protein-arginine kinase [mcsB]. 3 339 34.555 T 12-10-2018 IPR023660 Protein arginine kinase GO:0016775 NPD12_3673 dda0f8b0e07606980ccc7b6b6877b54d 347 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 44 241 5.1E-72 T 12-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 NPD12_3673 dda0f8b0e07606980ccc7b6b6877b54d 347 Gene3D G3DSA:3.30.590.10 2 251 1.2E-70 T 12-10-2018 NPD12_2649 be3efdd854872ca37cd0d9c641ae44e0 351 SUPERFAMILY SSF52218 165 327 7.94E-14 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2649 be3efdd854872ca37cd0d9c641ae44e0 351 Pfam PF03358 NADPH-dependent FMN reductase 165 321 2.1E-14 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_2649 be3efdd854872ca37cd0d9c641ae44e0 351 Gene3D G3DSA:3.40.50.360 165 351 4.5E-22 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_3659 2f4b9e2d8c7e1d5b997bd6c97db17d96 169 Pfam PF05991 YacP-like NYN domain 4 167 1.1E-53 T 12-10-2018 IPR010298 Protein of unknown function DUF901 NPD12_3040 8b09a15150c3166c35a58de13062fe8f 137 Gene3D G3DSA:3.30.2220.30 10 125 5.4E-29 T 12-10-2018 IPR038559 Clostridium phage phiCD119, XkdN superfamily NPD12_3040 8b09a15150c3166c35a58de13062fe8f 137 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 5 136 6.3E-36 T 12-10-2018 IPR014986 Clostridium phage phiCD119, XkdN NPD12_761 3eae43c6ea4e9f1bc820c64829f2c190 165 Gene3D G3DSA:3.40.630.30 1 163 1.5E-17 T 12-10-2018 NPD12_761 3eae43c6ea4e9f1bc820c64829f2c190 165 SUPERFAMILY SSF55729 4 147 1.85E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_416 41fcfc78a147e9e75be7435c6520180a 300 SUPERFAMILY SSF55729 27 247 1.08E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_416 41fcfc78a147e9e75be7435c6520180a 300 Pfam PF13527 Acetyltransferase (GNAT) domain 29 139 3.5E-13 T 12-10-2018 NPD12_416 41fcfc78a147e9e75be7435c6520180a 300 Gene3D G3DSA:3.40.630.30 17 179 2.8E-24 T 12-10-2018 NPD12_3558 c3d1e0869554e87065f794ba5791555e 441 PRINTS PR00173 Glutamate-aspartate symporter signature 380 399 5.3E-5 T 12-10-2018 NPD12_3558 c3d1e0869554e87065f794ba5791555e 441 PRINTS PR00173 Glutamate-aspartate symporter signature 229 254 5.3E-5 T 12-10-2018 NPD12_3558 c3d1e0869554e87065f794ba5791555e 441 PRINTS PR00173 Glutamate-aspartate symporter signature 151 171 5.3E-5 T 12-10-2018 NPD12_3558 c3d1e0869554e87065f794ba5791555e 441 PRINTS PR00173 Glutamate-aspartate symporter signature 200 220 5.3E-5 T 12-10-2018 NPD12_3558 c3d1e0869554e87065f794ba5791555e 441 Pfam PF03553 Na+/H+ antiporter family 58 213 4.2E-16 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 NPD12_3558 c3d1e0869554e87065f794ba5791555e 441 Pfam PF03553 Na+/H+ antiporter family 231 426 5.8E-13 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 NPD12_550 20e67ffe7fc8a4907ec78e3dec215ac6 134 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 1 132 9.8E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_550 20e67ffe7fc8a4907ec78e3dec215ac6 134 SUPERFAMILY SSF161098 1 128 1.83E-17 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_550 20e67ffe7fc8a4907ec78e3dec215ac6 134 Gene3D G3DSA:1.10.3720.10 1 134 5.9E-13 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_3053 5daeeaae047a179ffe210888a1d7ecde 468 TIGRFAM TIGR01538 portal_SPP1: phage portal protein, SPP1 family 6 442 1.7E-58 T 12-10-2018 IPR006428 Portal protein, SPP1-type NPD12_3053 5daeeaae047a179ffe210888a1d7ecde 468 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 20 446 7.1E-89 T 12-10-2018 IPR021145 Portal protein NPD12_2807 4c643a9696bd8570f4f0fadaf51ebf97 390 Gene3D G3DSA:1.20.1530.20 2 389 2.9E-45 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily NPD12_2807 4c643a9696bd8570f4f0fadaf51ebf97 390 Pfam PF00999 Sodium/hydrogen exchanger family 8 380 5.0E-41 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 NPD12_1414 9a3d886cb7330b9fb05660c0d47736b0 317 Gene3D G3DSA:1.10.3720.10 85 307 1.0E-25 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1414 9a3d886cb7330b9fb05660c0d47736b0 317 SUPERFAMILY SSF161098 90 301 9.81E-22 T 12-10-2018 IPR035906 MetI-like superfamily NPD12_1414 9a3d886cb7330b9fb05660c0d47736b0 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.0E-47 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 NPD12_2982 1a3bc979c3ae3cf3f34bdaa436ba56ae 244 Pfam PF02591 C4-type zinc ribbon domain 200 232 1.3E-11 T 12-10-2018 IPR003743 C4-type zinc ribbon domain NPD12_1449 6568856d319d073bf43bf9e87a9eb9cd 106 Gene3D G3DSA:3.40.30.10 1 105 1.8E-25 T 12-10-2018 NPD12_1449 6568856d319d073bf43bf9e87a9eb9cd 106 Pfam PF00085 Thioredoxin 3 104 9.3E-23 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 NPD12_1449 6568856d319d073bf43bf9e87a9eb9cd 106 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 NPD12_1449 6568856d319d073bf43bf9e87a9eb9cd 106 SUPERFAMILY SSF52833 4 104 1.33E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily NPD12_1449 6568856d319d073bf43bf9e87a9eb9cd 106 PIRSF PIRSF000077 1 105 3.9E-23 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 NPD12_3554 2afc42a2ca70c4d30a18ec04b7e1552c 204 SUPERFAMILY SSF89392 34 201 2.67E-5 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX NPD12_3554 2afc42a2ca70c4d30a18ec04b7e1552c 204 Gene3D G3DSA:2.50.20.10 31 203 2.9E-9 T 12-10-2018 NPD12_3554 2afc42a2ca70c4d30a18ec04b7e1552c 204 PIRSF PIRSF033729 1 204 2.4E-55 T 12-10-2018 IPR014584 Uncharacterised conserved protein UCP033729 NPD12_789 6cf718d3c756b063b7ae1f174a2c183b 379 Pfam PF13303 Phosphotransferase system, EIIC 29 327 1.4E-59 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_1351 cefce48a14b046712edde6a2b3ac50a1 264 Gene3D G3DSA:3.40.50.300 1 256 2.0E-58 T 12-10-2018 NPD12_1351 cefce48a14b046712edde6a2b3ac50a1 264 SUPERFAMILY SSF52540 1 232 2.17E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_1351 cefce48a14b046712edde6a2b3ac50a1 264 SMART SM00382 31 226 3.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1351 cefce48a14b046712edde6a2b3ac50a1 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_1351 cefce48a14b046712edde6a2b3ac50a1 264 Pfam PF00005 ABC transporter 23 177 1.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_2249 8e9b484f8a9f47c1770fc2ca4dd724cd 148 Gene3D G3DSA:3.40.50.300 1 148 1.3E-15 T 12-10-2018 NPD12_2249 8e9b484f8a9f47c1770fc2ca4dd724cd 148 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 4 142 4.5E-32 T 12-10-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 NPD12_2249 8e9b484f8a9f47c1770fc2ca4dd724cd 148 PIRSF PIRSF036409 3 148 2.5E-55 T 12-10-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 NPD12_2249 8e9b484f8a9f47c1770fc2ca4dd724cd 148 SUPERFAMILY SSF52540 5 144 1.73E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3471 2f8ba9ed0fdbafec43896e745b7977e1 91 TIGRFAM TIGR04116 CXXX_rpt_assoc: CXXX repeat peptide modification system protein 6 89 2.0E-25 T 12-10-2018 IPR026413 CXXX repeat peptide modification system protein NPD12_2208 49351265f349b2a458d9431ae4ed62b4 299 SUPERFAMILY SSF53448 9 267 4.02E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2208 49351265f349b2a458d9431ae4ed62b4 299 Gene3D G3DSA:3.90.550.10 6 206 9.1E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2208 49351265f349b2a458d9431ae4ed62b4 299 Pfam PF00535 Glycosyl transferase family 2 9 164 2.8E-13 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 NPD12_1738 1165794f1db711ab32849f0c602dcecf 350 Gene3D G3DSA:3.20.20.210 1 343 2.9E-85 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_1738 1165794f1db711ab32849f0c602dcecf 350 SUPERFAMILY SSF51726 5 347 1.41E-62 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 NPD12_1738 1165794f1db711ab32849f0c602dcecf 350 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 343 4.7E-84 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 NPD12_2113 44276b5f3442d1cd0a9ddde9de352d11 440 Pfam PF01554 MatE 248 407 4.7E-24 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2113 44276b5f3442d1cd0a9ddde9de352d11 440 Pfam PF01554 MatE 23 183 5.8E-33 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2113 44276b5f3442d1cd0a9ddde9de352d11 440 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 418 5.9E-68 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2113 44276b5f3442d1cd0a9ddde9de352d11 440 PIRSF PIRSF006603 1 440 6.1E-107 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 NPD12_2239 5861f54a5f480543967591f493fdf814 91 Gene3D G3DSA:1.20.58.1000 1 89 4.7E-27 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily NPD12_2239 5861f54a5f480543967591f493fdf814 91 Pfam PF02583 Metal-sensitive transcriptional repressor 7 85 3.1E-25 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 NPD12_2214 a586d1e42923554d90723ee871c90345 429 Gene3D G3DSA:3.40.50.1820 34 429 4.6E-133 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_2214 a586d1e42923554d90723ee871c90345 429 SUPERFAMILY SSF53474 40 404 2.2E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_1208 a153d902f8db85eb4c96a9d534b0f749 232 SMART SM00873 61 215 8.6E-15 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 NPD12_1208 a153d902f8db85eb4c96a9d534b0f749 232 SUPERFAMILY SSF56037 50 227 9.42E-30 T 12-10-2018 NPD12_1208 a153d902f8db85eb4c96a9d534b0f749 232 Gene3D G3DSA:3.50.40.10 65 203 1.7E-6 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 NPD12_1208 a153d902f8db85eb4c96a9d534b0f749 232 Pfam PF03483 B3/4 domain 64 194 1.6E-24 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 NPD12_772 b611c2f307f0d5f55335f6548313ac3a 636 SUPERFAMILY SSF53649 252 613 1.24E-63 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 NPD12_772 b611c2f307f0d5f55335f6548313ac3a 636 Gene3D G3DSA:3.40.720.10 247 549 9.4E-71 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 NPD12_772 b611c2f307f0d5f55335f6548313ac3a 636 Pfam PF00884 Sulfatase 254 540 2.0E-41 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 NPD12_772 b611c2f307f0d5f55335f6548313ac3a 636 PIRSF PIRSF005091 1 625 2.3E-183 T 12-10-2018 IPR012160 Lipoteichoic acid synthase-like NPD12_626 4a114a344dad646b81ecf040e4ed4172 258 Pfam PF02596 Uncharacterised ArCR, COG2043 10 216 5.0E-49 T 12-10-2018 IPR003748 Protein of unknown function DUF169 NPD12_2133 f847e589fc8462450cf0e51655d424f3 251 Pfam PF02361 Cobalt transport protein 14 208 3.4E-19 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component NPD12_3353 9e19ef56b9851f01f02814d6ba7bb2c8 252 Gene3D G3DSA:3.30.420.40 93 231 4.7E-71 T 12-10-2018 NPD12_3353 9e19ef56b9851f01f02814d6ba7bb2c8 252 Gene3D G3DSA:3.30.420.40 4 247 4.7E-71 T 12-10-2018 NPD12_3353 9e19ef56b9851f01f02814d6ba7bb2c8 252 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 4 247 8.9E-76 T 12-10-2018 IPR008275 CoA enzyme activase NPD12_3353 9e19ef56b9851f01f02814d6ba7bb2c8 252 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 247 1.4E-54 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 NPD12_3353 9e19ef56b9851f01f02814d6ba7bb2c8 252 SUPERFAMILY SSF53067 2 247 6.51E-42 T 12-10-2018 NPD12_2642 19fa774754717965722499a16367f87c 256 Pfam PF06738 Putative threonine/serine exporter 9 248 2.0E-72 T 12-10-2018 IPR010619 Putative threonine/serine exporter NPD12_2584 3a8cdf2682897abca19c0e412c7ff737 424 Pfam PF13641 Glycosyltransferase like family 2 48 272 2.3E-30 T 12-10-2018 NPD12_2584 3a8cdf2682897abca19c0e412c7ff737 424 Gene3D G3DSA:3.90.550.10 34 269 3.8E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2584 3a8cdf2682897abca19c0e412c7ff737 424 SUPERFAMILY SSF53448 47 339 6.99E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases NPD12_2185 4ef86234f2fafef3cbf4de635a11bc79 71 Pfam PF01381 Helix-turn-helix 12 66 1.0E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2185 4ef86234f2fafef3cbf4de635a11bc79 71 SUPERFAMILY SSF47413 3 69 6.7E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 NPD12_2185 4ef86234f2fafef3cbf4de635a11bc79 71 SMART SM00530 11 66 7.6E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 NPD12_2185 4ef86234f2fafef3cbf4de635a11bc79 71 Gene3D G3DSA:1.10.260.40 7 71 1.4E-26 T 12-10-2018 NPD12_3098 b9edecefbc0e47b36d56d48acea9c344 616 SUPERFAMILY SSF102114 222 601 6.41E-48 T 12-10-2018 NPD12_3098 b9edecefbc0e47b36d56d48acea9c344 616 SMART SM00729 256 478 7.3E-34 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_3098 b9edecefbc0e47b36d56d48acea9c344 616 Pfam PF04055 Radical SAM superfamily 261 423 1.4E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_3098 b9edecefbc0e47b36d56d48acea9c344 616 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 6 609 0.0 T 12-10-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM NPD12_3098 b9edecefbc0e47b36d56d48acea9c344 616 Gene3D G3DSA:3.80.30.20 255 475 9.5E-20 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe NPD12_366 2d178b44b45064a14dedbc94364b8223 233 SMART SM00563 51 164 1.8E-25 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 NPD12_366 2d178b44b45064a14dedbc94364b8223 233 Pfam PF01553 Acyltransferase 36 162 2.3E-22 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 NPD12_366 2d178b44b45064a14dedbc94364b8223 233 SUPERFAMILY SSF69593 20 232 5.1E-47 T 12-10-2018 NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 Gene3D G3DSA:3.20.20.70 6 308 3.8E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 SUPERFAMILY SSF54862 128 400 2.57E-20 T 12-10-2018 NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 319 1.7E-58 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 SUPERFAMILY SSF51395 3 320 7.99E-65 T 12-10-2018 NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 Pfam PF01180 Dihydroorotate dehydrogenase 6 302 4.5E-32 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 378 389 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 Gene3D G3DSA:3.30.70.20 309 409 2.2E-21 T 12-10-2018 NPD12_2848 6c843723afea5f16fc5d9cf2574de270 411 Pfam PF14697 4Fe-4S dicluster domain 339 394 3.1E-19 T 12-10-2018 NPD12_2636 6eef50b906b928cfcebf7bceb6b13ebb 338 SUPERFAMILY SSF52402 56 274 9.78E-22 T 12-10-2018 NPD12_2636 6eef50b906b928cfcebf7bceb6b13ebb 338 Gene3D G3DSA:3.40.50.620 29 319 1.7E-17 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold NPD12_2636 6eef50b906b928cfcebf7bceb6b13ebb 338 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 70 133 4.1E-6 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PRINTS PR00175 Sodium/alanine symporter signature 89 111 8.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PRINTS PR00175 Sodium/alanine symporter signature 406 426 8.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PRINTS PR00175 Sodium/alanine symporter signature 303 321 8.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PRINTS PR00175 Sodium/alanine symporter signature 180 198 8.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PRINTS PR00175 Sodium/alanine symporter signature 208 227 8.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PRINTS PR00175 Sodium/alanine symporter signature 347 369 8.7E-55 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 Pfam PF01235 Sodium:alanine symporter family 49 440 7.6E-146 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PIRSF PIRSF006060 277 370 4.2 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PIRSF PIRSF006060 377 439 0.32 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 PIRSF PIRSF006060 34 258 6.7E-8 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 89 104 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2623 e0bc723c60a22cc7c2b5185b144aab8f 444 TIGRFAM TIGR00835 agcS: amino acid carrier protein 15 437 1.4E-152 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_216 c41725eddeefd19c9e24a08dccbfed28 67 SUPERFAMILY SSF55008 1 66 6.54E-12 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 NPD12_216 c41725eddeefd19c9e24a08dccbfed28 67 Pfam PF00403 Heavy-metal-associated domain 17 65 5.0E-7 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 NPD12_216 c41725eddeefd19c9e24a08dccbfed28 67 Gene3D G3DSA:3.30.70.100 2 67 1.2E-10 T 12-10-2018 NPD12_1772 bf5b0639b970fec0fc53993995c15dc0 121 SUPERFAMILY SSF54593 4 120 1.18E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_1772 bf5b0639b970fec0fc53993995c15dc0 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 117 1.5E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain NPD12_1772 bf5b0639b970fec0fc53993995c15dc0 121 Gene3D G3DSA:3.10.180.10 5 118 3.0E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_2197 b286ba6563a0117a2e91f4d9bc575fd4 703 SUPERFAMILY SSF52540 152 508 1.16E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_421 dfc4c88bce68e4972c8321e4ff963f0c 101 Gene3D G3DSA:3.30.365.20 1 99 4.5E-19 T 12-10-2018 NPD12_421 dfc4c88bce68e4972c8321e4ff963f0c 101 SUPERFAMILY SSF56003 3 96 6.8E-21 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 NPD12_2774 eef805cf40e90768f9f5282d72057723 134 Pfam PF05130 FlgN protein 1 133 2.1E-22 T 12-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 NPD12_2774 eef805cf40e90768f9f5282d72057723 134 SUPERFAMILY SSF140566 3 120 2.35E-16 T 12-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 NPD12_802 eeee6c47aae57755c6441d020a7aad90 196 Gene3D G3DSA:1.10.3210.10 2 146 2.7E-6 T 12-10-2018 NPD12_802 eeee6c47aae57755c6441d020a7aad90 196 SUPERFAMILY SSF109604 11 116 2.13E-8 T 12-10-2018 NPD12_398 cf8316c323a34980a837538836089507 106 SUPERFAMILY SSF46973 2 99 2.09E-33 T 12-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 NPD12_398 cf8316c323a34980a837538836089507 106 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 99 1.3E-33 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 NPD12_398 cf8316c323a34980a837538836089507 106 PIRSF PIRSF000699 1 106 2.8E-34 T 12-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 NPD12_398 cf8316c323a34980a837538836089507 106 Gene3D G3DSA:1.20.58.280 1 103 4.9E-34 T 12-10-2018 NPD12_1923 1565d6189085ac11f30972c6d0603747 319 Gene3D G3DSA:3.40.1190.20 4 318 1.9E-82 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1923 1565d6189085ac11f30972c6d0603747 319 SUPERFAMILY SSF53613 11 309 8.57E-59 T 12-10-2018 IPR029056 Ribokinase-like NPD12_1923 1565d6189085ac11f30972c6d0603747 319 Pfam PF00294 pfkB family carbohydrate kinase 9 298 4.2E-47 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB NPD12_1923 1565d6189085ac11f30972c6d0603747 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 NPD12_1660 6fed0701d9ae0775f36dd5d487ef0cde 251 SMART SM00382 31 219 2.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_1660 6fed0701d9ae0775f36dd5d487ef0cde 251 Gene3D G3DSA:3.40.50.300 2 239 2.9E-62 T 12-10-2018 NPD12_1660 6fed0701d9ae0775f36dd5d487ef0cde 251 Pfam PF00005 ABC transporter 22 170 5.9E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_1660 6fed0701d9ae0775f36dd5d487ef0cde 251 SUPERFAMILY SSF52540 3 227 5.19E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3481 13d16306817077c4c4e5dc07769ec820 363 Gene3D G3DSA:3.40.50.300 11 212 2.9E-7 T 12-10-2018 NPD12_3481 13d16306817077c4c4e5dc07769ec820 363 SUPERFAMILY SSF52540 11 77 5.12E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3481 13d16306817077c4c4e5dc07769ec820 363 SUPERFAMILY SSF52540 116 296 7.16E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_969 8c7a466ea496c2757b5b7cb692cfc4f3 898 Pfam PF02687 FtsX-like permease family 333 427 2.3E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_969 8c7a466ea496c2757b5b7cb692cfc4f3 898 Pfam PF02687 FtsX-like permease family 798 889 8.4E-13 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_1447 4d867cd9582f4fddd56a7b8f7ef166a1 64 TIGRFAM TIGR01918 various_sel_PB: selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family 1 64 5.3E-31 T 12-10-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 NPD12_1551 5ae082bf7339dbe5bac9323163219690 88 Gene3D G3DSA:1.20.58.1000 1 83 6.6E-29 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily NPD12_1551 5ae082bf7339dbe5bac9323163219690 88 Pfam PF02583 Metal-sensitive transcriptional repressor 4 84 2.6E-27 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 NPD12_622 ec4db95394a64a0bff95b0a84f82b074 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 274 1.4E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 NPD12_2396 7fb3b2cee88e6d96a7ac97091d34f9ed 55 Pfam PF09388 Spo0E like sporulation regulatory protein 7 49 1.4E-11 T 12-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 NPD12_2396 7fb3b2cee88e6d96a7ac97091d34f9ed 55 SUPERFAMILY SSF140500 5 54 1.44E-10 T 12-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 NPD12_93 17d6195dd4123510bb519102297a863e 249 Pfam PF01643 Acyl-ACP thioesterase 6 248 4.3E-67 T 12-10-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 NPD12_93 17d6195dd4123510bb519102297a863e 249 SUPERFAMILY SSF54637 145 248 8.48E-25 T 12-10-2018 IPR029069 HotDog domain superfamily NPD12_93 17d6195dd4123510bb519102297a863e 249 SUPERFAMILY SSF54637 3 140 4.22E-42 T 12-10-2018 IPR029069 HotDog domain superfamily NPD12_93 17d6195dd4123510bb519102297a863e 249 Gene3D G3DSA:3.10.129.10 6 249 4.7E-71 T 12-10-2018 NPD12_2389 ae02729ec2cc7f3ba297182b89eb5ca5 110 Pfam PF12788 YmaF family 8 102 1.0E-39 T 12-10-2018 IPR024307 YmaF NPD12_1331 273b63cb53c85f5c226343a87b9aa677 190 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 190 39.723 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 NPD12_1331 273b63cb53c85f5c226343a87b9aa677 190 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 188 8.1E-68 T 12-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 NPD12_1331 273b63cb53c85f5c226343a87b9aa677 190 Gene3D G3DSA:3.40.50.2020 3 189 1.8E-48 T 12-10-2018 NPD12_1331 273b63cb53c85f5c226343a87b9aa677 190 SUPERFAMILY SSF53271 1 189 8.43E-41 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_547 2d688339c249ab0b0eb24dc3167fb9d5 329 Pfam PF01757 Acyltransferase family 1 313 6.1E-29 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 NPD12_3117 d5ceac6a3594a91b3ef7cd211aed96b0 181 Pfam PF01464 Transglycosylase SLT domain 35 148 2.1E-31 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 NPD12_3117 d5ceac6a3594a91b3ef7cd211aed96b0 181 SUPERFAMILY SSF53955 30 180 1.03E-46 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily NPD12_3117 d5ceac6a3594a91b3ef7cd211aed96b0 181 Gene3D G3DSA:1.10.530.10 26 181 4.8E-51 T 12-10-2018 NPD12_2011 7a69d213bb5e1eb703c81f182644690a 122 SUPERFAMILY SSF81891 19 106 3.84E-8 T 12-10-2018 NPD12_2011 7a69d213bb5e1eb703c81f182644690a 122 Gene3D G3DSA:1.10.3090.10 1 104 2.2E-11 T 12-10-2018 NPD12_746 a27e15c0e76a6b71d37a136e5806f262 67 ProDom PD019268 UVIB BACTERIOCIN BHLA PLASMID ANTIBIOTIC HOLIN-LIKE PRECURSOR ANTIMICROBIAL SIGNAL PROPHAGE-DERIVED 1 60 5.0E-16 T 12-10-2018 IPR024405 Prophage protein BhlA/UviB NPD12_746 a27e15c0e76a6b71d37a136e5806f262 67 Pfam PF10960 BhlA holin family 1 56 2.0E-15 T 12-10-2018 IPR024405 Prophage protein BhlA/UviB NPD12_2159 13ee44baa2bff988168ce42b91b30b3b 289 SUPERFAMILY SSF102114 4 238 4.32E-35 T 12-10-2018 NPD12_2159 13ee44baa2bff988168ce42b91b30b3b 289 Pfam PF04055 Radical SAM superfamily 21 174 4.4E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 NPD12_2159 13ee44baa2bff988168ce42b91b30b3b 289 SMART SM00729 15 233 6.4E-35 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 NPD12_2159 13ee44baa2bff988168ce42b91b30b3b 289 Gene3D G3DSA:3.20.20.70 14 273 2.4E-18 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 NPD12_2285 859f2bd5d658bf4b4847cc4b05605891 117 Pfam PF17032 zinc-ribbon family 21 77 2.8E-8 T 12-10-2018 IPR031493 Zinc-ribbon 15 NPD12_2540 c63c55e4b67d59097d3a3f9ad3fa03fd 388 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 24 379 9.7E-145 T 12-10-2018 IPR014226 Sporulation integral membrane protein YlbJ NPD12_897 e6ec9df5a9d4fbd40d6ef6568011cd1b 32 SUPERFAMILY SSF46955 4 31 7.33E-5 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_2101 fa5eb2455466ca1579b215e7a78dd0cb 75 Gene3D G3DSA:3.10.20.30 1 75 3.5E-12 T 12-10-2018 IPR012675 Beta-grasp domain superfamily NPD12_2101 fa5eb2455466ca1579b215e7a78dd0cb 75 Pfam PF02597 ThiS family 5 75 3.0E-10 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 NPD12_2101 fa5eb2455466ca1579b215e7a78dd0cb 75 SUPERFAMILY SSF54285 2 75 2.47E-14 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp NPD12_2277 529330af1fbb1ec1b456307934b87f53 361 SUPERFAMILY SSF51905 4 319 1.9E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_2277 529330af1fbb1ec1b456307934b87f53 361 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 9.4E-15 T 12-10-2018 NPD12_2277 529330af1fbb1ec1b456307934b87f53 361 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 296 9.4E-15 T 12-10-2018 NPD12_2277 529330af1fbb1ec1b456307934b87f53 361 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 265 280 9.4E-15 T 12-10-2018 NPD12_2277 529330af1fbb1ec1b456307934b87f53 361 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.4E-15 T 12-10-2018 NPD12_2277 529330af1fbb1ec1b456307934b87f53 361 Gene3D G3DSA:3.50.50.60 2 351 3.8E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily NPD12_1184 035118b2b12d6de1cf6e25cb3d0aed3f 251 Pfam PF13803 Domain of unknown function (DUF4184) 1 248 1.7E-75 T 12-10-2018 IPR025238 Protein of unknown function DUF4184 NPD12_2999 b47c15ba7144359bc13ebe831c4feb32 386 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 3 373 8.1E-144 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD NPD12_2999 b47c15ba7144359bc13ebe831c4feb32 386 PIRSF PIRSF029895 1 384 3.2E-79 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD NPD12_2999 b47c15ba7144359bc13ebe831c4feb32 386 Pfam PF06898 Putative stage IV sporulation protein YqfD 6 371 1.3E-109 T 12-10-2018 IPR010690 Putative stage IV sporulation YqfD NPD12_578 4ae9de2418f1d19391bf7d11115be162 284 Pfam PF02673 Bacitracin resistance protein BacA 7 271 4.0E-84 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 NPD12_578 4ae9de2418f1d19391bf7d11115be162 284 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 269 2.8E-73 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 NPD12_578 4ae9de2418f1d19391bf7d11115be162 284 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 276 18.074 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 NPD12_2829 63e3569b1e54ffd4574b5969f7e2905e 372 Gene3D G3DSA:1.20.1740.10 3 369 1.6E-5 T 12-10-2018 NPD12_2829 63e3569b1e54ffd4574b5969f7e2905e 372 Pfam PF03845 Spore germination protein 9 319 7.1E-56 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_2829 63e3569b1e54ffd4574b5969f7e2905e 372 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 362 2.1E-97 T 12-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 NPD12_1767 10865fd1416f64cd4aabc4fa0dffdd5e 115 Pfam PF03860 Domain of Unknown Function (DUF326) 71 89 2.3E-4 T 12-10-2018 IPR005560 Protein of unknown function DUF326 NPD12_1767 10865fd1416f64cd4aabc4fa0dffdd5e 115 Gene3D G3DSA:1.20.1270.360 9 114 2.2E-26 T 12-10-2018 NPD12_3473 f6446da5161017e1362cc23a2d73e502 96 TIGRFAM TIGR04116 CXXX_rpt_assoc: CXXX repeat peptide modification system protein 6 93 7.7E-31 T 12-10-2018 IPR026413 CXXX repeat peptide modification system protein NPD12_1817 64110a1f769c88a93a0484598065fa2a 175 Pfam PF04143 Sulphur transport 5 165 2.0E-35 T 12-10-2018 IPR007272 Sulphur transport domain NPD12_1354 42c4655422108ad5af7bfdd9015ca509 293 SUPERFAMILY SSF103481 39 141 1.02E-16 T 12-10-2018 NPD12_1354 42c4655422108ad5af7bfdd9015ca509 293 SUPERFAMILY SSF103481 189 290 3.92E-17 T 12-10-2018 NPD12_1354 42c4655422108ad5af7bfdd9015ca509 293 Pfam PF00892 EamA-like transporter family 6 140 4.6E-32 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_1354 42c4655422108ad5af7bfdd9015ca509 293 Pfam PF00892 EamA-like transporter family 154 288 9.6E-33 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 NPD12_3410 3da5841773554bea613e9ac691853e46 177 Pfam PF00583 Acetyltransferase (GNAT) family 48 151 1.7E-18 T 12-10-2018 IPR000182 GNAT domain NPD12_3410 3da5841773554bea613e9ac691853e46 177 SUPERFAMILY SSF55729 8 175 1.1E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_3410 3da5841773554bea613e9ac691853e46 177 Gene3D G3DSA:3.40.630.30 10 177 1.7E-38 T 12-10-2018 NPD12_1862 d39408c849c8b444f1b9fc2d26354eac 226 Gene3D G3DSA:3.40.109.40 1 199 1.2E-65 T 12-10-2018 NPD12_1862 d39408c849c8b444f1b9fc2d26354eac 226 PIRSF PIRSF037984 1 222 2.6E-70 T 12-10-2018 IPR017342 S-adenosyl-L-methionine dependent methionine synthase, predicted NPD12_1862 d39408c849c8b444f1b9fc2d26354eac 226 SUPERFAMILY SSF56507 15 193 5.89E-29 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 NPD12_295 60bf280fd625b066e877d3579777e6dc 239 Pfam PF02535 ZIP Zinc transporter 92 234 7.7E-26 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 NPD12_921 7d986d5add976d8b598b5bcb2c08d89b 166 SUPERFAMILY SSF51182 2 165 8.01E-59 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_921 7d986d5add976d8b598b5bcb2c08d89b 166 Gene3D G3DSA:2.60.120.10 1 165 1.6E-62 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_921 7d986d5add976d8b598b5bcb2c08d89b 166 Pfam PF06172 Cupin superfamily (DUF985) 6 143 1.5E-44 T 12-10-2018 IPR009327 Cupin domain of unknown function DUF985 NPD12_3077 9ca433b04db198a5936023cb1550d53d 150 Gene3D G3DSA:3.40.390.50 1 112 5.4E-7 T 12-10-2018 NPD12_3077 9ca433b04db198a5936023cb1550d53d 150 Pfam PF06114 IrrE N-terminal-like domain 25 147 5.0E-19 T 12-10-2018 IPR010359 IrrE N-terminal-like domain NPD12_352 19308d802d80aa7592a625d8b0312158 94 Pfam PF14276 Domain of unknown function (DUF4363) 2 93 3.4E-26 T 12-10-2018 IPR025373 Protein of unknown function DUF4363 NPD12_410 90639d268ec39a75e7ca1f63d112f779 219 SUPERFAMILY SSF51182 66 201 6.43E-24 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_410 90639d268ec39a75e7ca1f63d112f779 219 Gene3D G3DSA:2.60.120.10 94 219 3.5E-43 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_410 90639d268ec39a75e7ca1f63d112f779 219 Pfam PF07883 Cupin domain 119 194 1.1E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel NPD12_3417 fad833d27ee8b3e23b3333f430978e8d 374 Gene3D G3DSA:3.40.50.11900 233 374 1.5E-49 T 12-10-2018 NPD12_3417 fad833d27ee8b3e23b3333f430978e8d 374 Gene3D G3DSA:1.20.1270.370 11 221 1.0E-78 T 12-10-2018 NPD12_3417 fad833d27ee8b3e23b3333f430978e8d 374 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 40 374 2.3E-66 T 12-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit NPD12_3417 fad833d27ee8b3e23b3333f430978e8d 374 Gene3D G3DSA:3.40.50.11890 31 156 1.0E-78 T 12-10-2018 NPD12_453 9a0798f5e95baa9bbd5a8822f21e2045 253 Gene3D G3DSA:1.10.10.10 4 73 7.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_453 9a0798f5e95baa9bbd5a8822f21e2045 253 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 68 4.2E-10 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 NPD12_453 9a0798f5e95baa9bbd5a8822f21e2045 253 SUPERFAMILY SSF46689 10 73 3.94E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 NPD12_453 9a0798f5e95baa9bbd5a8822f21e2045 253 Gene3D G3DSA:3.40.50.10490 87 253 4.7E-28 T 12-10-2018 NPD12_453 9a0798f5e95baa9bbd5a8822f21e2045 253 Pfam PF01380 SIS domain 116 217 3.7E-12 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 NPD12_453 9a0798f5e95baa9bbd5a8822f21e2045 253 SUPERFAMILY SSF53697 87 252 1.07E-26 T 12-10-2018 NPD12_935 f48ea1f603bc6ad0b3513411a11f9baf 218 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 59 198 9.0E-17 T 12-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase NPD12_642 0c88e039a817a68e4f829aa0cdb4001d 53 Pfam PF07561 Domain of Unknown Function (DUF1540) 7 49 6.7E-13 T 12-10-2018 IPR011437 Domain of unknown function DUF1540 NPD12_781 a02d94722925cef5de16b4e568798c0b 303 Pfam PF02517 CAAX protease self-immunity 150 243 5.5E-9 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 NPD12_845 9d5352c7a247c26d1eac8b57dfb25621 251 Gene3D G3DSA:3.40.50.300 1 247 3.2E-57 T 12-10-2018 NPD12_845 9d5352c7a247c26d1eac8b57dfb25621 251 SUPERFAMILY SSF52540 1 232 1.7E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_845 9d5352c7a247c26d1eac8b57dfb25621 251 Pfam PF00005 ABC transporter 23 176 8.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_845 9d5352c7a247c26d1eac8b57dfb25621 251 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_845 9d5352c7a247c26d1eac8b57dfb25621 251 SMART SM00382 31 224 1.4E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_659 45d1484acd4e165eaafd3f05a7de5e80 310 SUPERFAMILY SSF52540 3 226 1.02E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_659 45d1484acd4e165eaafd3f05a7de5e80 310 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_659 45d1484acd4e165eaafd3f05a7de5e80 310 SMART SM00382 28 211 6.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_659 45d1484acd4e165eaafd3f05a7de5e80 310 Pfam PF00005 ABC transporter 19 162 9.4E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_659 45d1484acd4e165eaafd3f05a7de5e80 310 Gene3D G3DSA:3.40.50.300 1 240 3.3E-75 T 12-10-2018 NPD12_1000 4e557f2714a2d25b180d84c62589c13f 437 Pfam PF05525 Branched-chain amino acid transport protein 7 423 2.7E-123 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 NPD12_1000 4e557f2714a2d25b180d84c62589c13f 437 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 412 8.5E-106 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 NPD12_3422 9816944e661e6066b584a7cb2451e940 440 Pfam PF05525 Branched-chain amino acid transport protein 7 425 1.7E-111 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 NPD12_3422 9816944e661e6066b584a7cb2451e940 440 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 412 1.1E-96 T 12-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 NPD12_1661 0f718c94c03268c1087df5df7375a2dc 602 PIRSF PIRSF018968 1 602 1.3E-60 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 NPD12_1801 4d3bb365b9ddd520badf3bc249d3da25 139 SUPERFAMILY SSF55961 4 131 3.47E-13 T 12-10-2018 NPD12_2942 62408443dfa1c802bb5043df1fae3f4b 245 TIGRFAM TIGR03172 TIGR03172: putative selenium-dependent hydroxylase accessory protein YqeC 14 237 4.3E-49 T 12-10-2018 IPR017587 Putative selenium-dependent hydroxylase accessory protein YqeC NPD12_1338 3597f04edd96402b762142f97f1eefb6 55 Gene3D G3DSA:2.10.260.10 1 17 4.9E-5 T 12-10-2018 NPD12_3438 659ea9dd6cc8e62da6ac0f2a26cf9cbb 472 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 316 426 3.4E-24 T 12-10-2018 IPR025299 CstA, C-terminal domain NPD12_3438 659ea9dd6cc8e62da6ac0f2a26cf9cbb 472 Pfam PF02554 Carbon starvation protein CstA 4 142 3.8E-32 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 NPD12_512 b2aa32dd5433d7a3d1437ebb35120c4b 155 Pfam PF11385 Protein of unknown function (DUF3189) 1 147 1.8E-55 T 12-10-2018 IPR021525 Protein of unknown function DUF3189 NPD12_1898 b80d504f45cc8518266aecc5491abcaf 184 Gene3D G3DSA:1.20.120.520 1 162 6.5E-27 T 12-10-2018 NPD12_1898 b80d504f45cc8518266aecc5491abcaf 184 Pfam PF01814 Hemerythrin HHE cation binding domain 3 139 2.1E-15 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 NPD12_2992 e587d854a5a2762e243cabf7331a679d 206 SUPERFAMILY SSF46934 1 44 1.33E-10 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 NPD12_2992 e587d854a5a2762e243cabf7331a679d 206 Pfam PF14242 Domain of unknown function (DUF4342) 45 124 9.2E-28 T 12-10-2018 IPR025642 Domain of unknown function DUF4342 NPD12_2992 e587d854a5a2762e243cabf7331a679d 206 Gene3D G3DSA:1.10.8.10 1 52 1.8E-6 T 12-10-2018 NPD12_2868 96cd5db70f26ffe926db47b8e8037f67 305 Pfam PF01458 Uncharacterized protein family (UPF0051) 79 303 1.9E-49 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 NPD12_2868 96cd5db70f26ffe926db47b8e8037f67 305 SUPERFAMILY SSF101960 48 304 1.07E-41 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily NPD12_2581 8435ab433edf7b62feaa24fd96a0df9e 258 Pfam PF03419 Sporulation factor SpoIIGA 2 256 1.1E-61 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 NPD12_2581 8435ab433edf7b62feaa24fd96a0df9e 258 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 258 7.2E-69 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 NPD12_2581 8435ab433edf7b62feaa24fd96a0df9e 258 PIRSF PIRSF018571 1 258 1.7E-64 T 12-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 NPD12_2851 ddd070341b4bac044160e7799ef0454f 351 Pfam PF02698 DUF218 domain 165 316 1.9E-29 T 12-10-2018 IPR003848 Domain of unknown function DUF218 NPD12_1176 17dd532268dd86a92e8e4753a34521cd 171 Pfam PF04892 VanZ like family 10 127 4.0E-19 T 12-10-2018 IPR006976 VanZ-like NPD12_2158 a1daf909d039c81274b7e0e3494cdcc1 131 Pfam PF01042 Endoribonuclease L-PSP 16 130 2.8E-16 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 NPD12_2158 a1daf909d039c81274b7e0e3494cdcc1 131 SUPERFAMILY SSF55298 7 131 3.87E-24 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 NPD12_2158 a1daf909d039c81274b7e0e3494cdcc1 131 Gene3D G3DSA:3.30.1330.40 10 131 5.1E-20 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 NPD12_423 7e272318f67fca96a3869eda86ce7cad 117 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 4 117 4.5E-45 T 12-10-2018 IPR014204 Sporulation stage V, protein AE NPD12_423 7e272318f67fca96a3869eda86ce7cad 117 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 4 112 3.5E-36 T 12-10-2018 IPR005562 SpoVA NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 PRINTS PR00175 Sodium/alanine symporter signature 94 116 9.5E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 PRINTS PR00175 Sodium/alanine symporter signature 351 373 9.5E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 PRINTS PR00175 Sodium/alanine symporter signature 212 231 9.5E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 PRINTS PR00175 Sodium/alanine symporter signature 410 430 9.5E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 PRINTS PR00175 Sodium/alanine symporter signature 307 325 9.5E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 PRINTS PR00175 Sodium/alanine symporter signature 184 202 9.5E-53 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 Pfam PF01235 Sodium:alanine symporter family 56 446 3.0E-146 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 94 109 - T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_2955 eb75855c60d91d6df69bb64068f1a80b 450 TIGRFAM TIGR00835 agcS: amino acid carrier protein 15 441 1.0E-147 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 NPD12_1182 541d335a4e8eaa272f2ce2594f1b48c4 719 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 499 700 5.7E-46 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal NPD12_1182 541d335a4e8eaa272f2ce2594f1b48c4 719 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 170 9.7E-46 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal NPD12_1182 541d335a4e8eaa272f2ce2594f1b48c4 719 SUPERFAMILY SSF58104 190 430 3.4E-5 T 12-10-2018 NPD12_1182 541d335a4e8eaa272f2ce2594f1b48c4 719 Pfam PF12698 ABC-2 family transporter protein 23 164 5.5E-8 T 12-10-2018 NPD12_2200 8ca56fd091b828cd82eafce353889bb4 97 Pfam PF07505 Protein of unknown function (DUF5131) 4 72 6.3E-16 T 12-10-2018 IPR011101 Protein of unknown function DUF5131 NPD12_2951 bc64b7f61fa13db9f77c8c76c4c0207d 190 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 5 180 5.5E-21 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain NPD12_2951 bc64b7f61fa13db9f77c8c76c4c0207d 190 Gene3D G3DSA:3.40.50.1110 1 189 3.4E-58 T 12-10-2018 IPR036514 SGNH hydrolase superfamily NPD12_2951 bc64b7f61fa13db9f77c8c76c4c0207d 190 SUPERFAMILY SSF52266 1 189 1.5E-39 T 12-10-2018 NPD12_1137 236eaaaee6f1494d46b59c50caaa3d7a 162 Gene3D G3DSA:1.10.1760.20 1 160 4.9E-22 T 12-10-2018 NPD12_1137 236eaaaee6f1494d46b59c50caaa3d7a 162 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 97 0.005 T 12-10-2018 NPD12_1137 236eaaaee6f1494d46b59c50caaa3d7a 162 Pfam PF12822 ECF transporter, substrate-specific component 4 150 7.0E-19 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 NPD12_333 c7ea78d67c62d89ef6c054d95567ca00 454 SUPERFAMILY SSF53187 26 407 4.1E-50 T 12-10-2018 NPD12_333 c7ea78d67c62d89ef6c054d95567ca00 454 Pfam PF04389 Peptidase family M28 213 403 2.1E-40 T 12-10-2018 IPR007484 Peptidase M28 NPD12_333 c7ea78d67c62d89ef6c054d95567ca00 454 Gene3D G3DSA:3.40.630.10 133 411 3.8E-45 T 12-10-2018 NPD12_1348 adf387b8a90747625ea28e0525a3b80c 138 Pfam PF09021 HutP 8 133 3.5E-45 T 12-10-2018 IPR015111 Hut operon regulatory protein HutP NPD12_3214 16d5b1fa76d3773ecc6df93c69396b4c 435 Pfam PF13440 Polysaccharide biosynthesis protein 27 319 4.8E-13 T 12-10-2018 NPD12_3214 16d5b1fa76d3773ecc6df93c69396b4c 435 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 324 409 3.5E-17 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain NPD12_798 20499594e44e89af4af4e613c8e987e1 156 Gene3D G3DSA:3.40.630.30 3 156 3.1E-32 T 12-10-2018 NPD12_798 20499594e44e89af4af4e613c8e987e1 156 SUPERFAMILY SSF55729 1 152 2.99E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_798 20499594e44e89af4af4e613c8e987e1 156 Pfam PF00583 Acetyltransferase (GNAT) family 49 145 5.5E-16 T 12-10-2018 IPR000182 GNAT domain NPD12_1440 98fc513fc9b3262b33fc611a6d882757 248 Pfam PF17115 N-terminal domain of toast_rack, DUF2154 47 139 1.5E-34 T 12-10-2018 IPR031346 Uncharacterised protein DUF2154, N-terminal NPD12_1440 98fc513fc9b3262b33fc611a6d882757 248 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 140 245 3.0E-7 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF NPD12_1191 847f9e871ed677deebdf3fad2ac28fb3 272 Gene3D G3DSA:1.10.150.320 177 252 4.6E-6 T 12-10-2018 NPD12_1191 847f9e871ed677deebdf3fad2ac28fb3 272 SUPERFAMILY SSF47781 182 255 4.45E-11 T 12-10-2018 IPR010994 RuvA domain 2-like NPD12_1191 847f9e871ed677deebdf3fad2ac28fb3 272 Pfam PF12836 Helix-hairpin-helix motif 190 252 2.6E-10 T 12-10-2018 NPD12_541 fc9815b56b9425048ddd1870f2f5ea83 344 Gene3D G3DSA:3.10.520.20 22 343 9.7E-115 T 12-10-2018 NPD12_541 fc9815b56b9425048ddd1870f2f5ea83 344 PIRSF PIRSF006268 2 337 5.2E-111 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 NPD12_541 fc9815b56b9425048ddd1870f2f5ea83 344 SUPERFAMILY SSF143631 29 332 2.35E-97 T 12-10-2018 IPR003374 ApbE-like superfamily NPD12_541 fc9815b56b9425048ddd1870f2f5ea83 344 Pfam PF02424 ApbE family 37 315 3.6E-84 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 NPD12_574 0a4c7177081aecbea6045e391dfe1072 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 4 198 6.2E-45 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 NPD12_574 0a4c7177081aecbea6045e391dfe1072 242 Gene3D G3DSA:3.40.50.880 15 211 2.7E-10 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_574 0a4c7177081aecbea6045e391dfe1072 242 SUPERFAMILY SSF52317 14 192 1.72E-27 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like NPD12_2555 3a1ac9fee0e26bc5f040adae6e329ffa 227 Pfam PF04298 Putative neutral zinc metallopeptidase 8 221 1.9E-92 T 12-10-2018 IPR007395 Putative neutral zinc metallopeptidase NPD12_783 6676d2a4e1893899d290621533c6ba5f 364 Pfam PF07532 Bacterial Ig-like domain (group 4) 136 185 9.0E-11 T 12-10-2018 IPR011081 Bacterial Ig-related NPD12_783 6676d2a4e1893899d290621533c6ba5f 364 Gene3D G3DSA:1.25.40.10 25 121 2.5E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_783 6676d2a4e1893899d290621533c6ba5f 364 SUPERFAMILY SSF48452 51 116 7.09E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_2732 694c061da2c7dba8a37cca5ecd3dbfa2 256 Pfam PF14393 Domain of unknown function (DUF4422) 4 225 1.7E-96 T 12-10-2018 IPR025536 Domain of unknown function DUF4422 NPD12_520 d1d74762ff5ee727afbe0b27c5ed2df8 224 Pfam PF09335 SNARE associated Golgi protein 67 183 3.4E-31 T 12-10-2018 IPR032816 SNARE associated Golgi protein NPD12_3193 9dae24741780b1867e28878966895e4b 118 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 7.6E-48 T 12-10-2018 IPR014204 Sporulation stage V, protein AE NPD12_3193 9dae24741780b1867e28878966895e4b 118 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 2 111 4.0E-33 T 12-10-2018 IPR005562 SpoVA NPD12_329 96ef837da20d9a96871149f5e1e4a2a3 225 SUPERFAMILY SSF53271 70 220 3.84E-25 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like NPD12_329 96ef837da20d9a96871149f5e1e4a2a3 225 Pfam PF00156 Phosphoribosyl transferase domain 133 219 2.9E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 NPD12_329 96ef837da20d9a96871149f5e1e4a2a3 225 Gene3D G3DSA:3.40.50.2020 92 223 1.7E-19 T 12-10-2018 NPD12_2808 a461adeb557ad683d4833226c369fbf4 116 SUPERFAMILY SSF54913 4 112 1.4E-5 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta NPD12_1104 fcfaaa6e51ae60a530f3084f951c51bc 211 Pfam PF13241 Putative NAD(P)-binding 8 109 2.7E-13 T 12-10-2018 NPD12_1104 fcfaaa6e51ae60a530f3084f951c51bc 211 Gene3D G3DSA:3.40.50.720 7 130 7.8E-17 T 12-10-2018 NPD12_1104 fcfaaa6e51ae60a530f3084f951c51bc 211 SUPERFAMILY SSF51735 7 103 7.09E-10 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1004 e59f0eac6d659bcaba85016bacee9a81 507 Pfam PF07664 Ferrous iron transport protein B C terminus 295 343 8.4E-15 T 12-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 NPD12_1004 e59f0eac6d659bcaba85016bacee9a81 507 Pfam PF07670 Nucleoside recognition 181 270 8.9E-6 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_1004 e59f0eac6d659bcaba85016bacee9a81 507 Pfam PF07670 Nucleoside recognition 353 477 1.6E-15 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_1409 ca7b29ad65266b3ab6f7f9751da332f3 230 Pfam PF04893 Yip1 domain 22 217 1.5E-22 T 12-10-2018 IPR006977 Yip1 domain GO:0016020 NPD12_870 2c3109979a172ab8ed877458e553648f 469 Pfam PF14199 Domain of unknown function (DUF4317) 1 465 4.6E-157 T 12-10-2018 IPR025466 Protein of unknown function DUF4317 NPD12_3820 8b058facb41962955f09d740f8452bd0 169 PIRSF PIRSF030140 1 169 5.4E-39 T 12-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 NPD12_3820 8b058facb41962955f09d740f8452bd0 169 Gene3D G3DSA:1.10.4010.10 1 169 5.3E-14 T 12-10-2018 NPD12_3820 8b058facb41962955f09d740f8452bd0 169 SUPERFAMILY SSF101386 2 169 5.67E-34 T 12-10-2018 NPD12_3820 8b058facb41962955f09d740f8452bd0 169 Pfam PF08761 dUTPase 2 169 1.0E-35 T 12-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 NPD12_493 fc0d05be63c271d20c5dd1240de57a6d 183 Pfam PF17248 Family of unknown function (DUF5317) 21 169 3.6E-24 T 12-10-2018 IPR035168 Protein of unknown function DUF5317 NPD12_3316 67c6deedf93392ab678747697669a4c5 430 PIRSF PIRSF005353 1 430 5.9E-181 T 12-10-2018 IPR026033 Purine permease PbuG-like NPD12_3316 67c6deedf93392ab678747697669a4c5 430 Pfam PF00860 Permease family 17 391 9.5E-46 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 NPD12_1739 ab2e4d1bea86238952456256e66bd924 465 Pfam PF03553 Na+/H+ antiporter family 30 220 6.9E-17 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 NPD12_1739 ab2e4d1bea86238952456256e66bd924 465 Pfam PF03553 Na+/H+ antiporter family 243 430 2.1E-5 T 12-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 NPD12_2276 e9e0f7f9b5a092d8e3ea2ab0d611507b 664 PIRSF PIRSF018968 1 664 1.3E-69 T 12-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 NPD12_2276 e9e0f7f9b5a092d8e3ea2ab0d611507b 664 Pfam PF02687 FtsX-like permease family 83 179 7.9E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_1657 b1dbf90e2e4b239387af0959db73127f 165 Gene3D G3DSA:1.10.530.10 27 163 4.9E-11 T 12-10-2018 NPD12_1657 b1dbf90e2e4b239387af0959db73127f 165 Pfam PF01464 Transglycosylase SLT domain 36 118 7.9E-5 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 NPD12_1657 b1dbf90e2e4b239387af0959db73127f 165 SUPERFAMILY SSF53955 31 119 5.22E-9 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily NPD12_3513 7bd5a2d56bbf8bd004eb7c87bf969d26 284 Pfam PF05368 NmrA-like family 4 223 2.6E-17 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 NPD12_3513 7bd5a2d56bbf8bd004eb7c87bf969d26 284 Gene3D G3DSA:3.40.50.720 4 265 6.6E-49 T 12-10-2018 NPD12_3513 7bd5a2d56bbf8bd004eb7c87bf969d26 284 Gene3D G3DSA:3.90.25.10 142 264 6.6E-49 T 12-10-2018 NPD12_3513 7bd5a2d56bbf8bd004eb7c87bf969d26 284 SUPERFAMILY SSF51735 4 250 1.24E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_1871 fc9a0ce5f5c02cf4b85783927e4694df 331 PIRSF PIRSF018567 1 331 2.2E-128 T 12-10-2018 IPR011391 Acetoin catabolism kinase AcoX NPD12_1871 fc9a0ce5f5c02cf4b85783927e4694df 331 Pfam PF01513 ATP-NAD kinase 3 201 1.5E-15 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 NPD12_1871 fc9a0ce5f5c02cf4b85783927e4694df 331 Gene3D G3DSA:3.40.50.10330 60 160 1.6E-5 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 NPD12_1871 fc9a0ce5f5c02cf4b85783927e4694df 331 SUPERFAMILY SSF111331 86 161 1.31E-8 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily NPD12_395 3373f43f56fc4287bf4afb7d66387241 436 Pfam PF02378 Phosphotransferase system, EIIC 33 361 2.1E-59 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 NPD12_395 3373f43f56fc4287bf4afb7d66387241 436 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 21 434 7.0E-111 T 12-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 NPD12_395 3373f43f56fc4287bf4afb7d66387241 436 PIRSF PIRSF006351 8 436 1.2E-123 T 12-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 NPD12_928 8bef5f1591d096a9ed0ea61c6b86f020 73 Pfam PF07872 Protein of unknown function (DUF1659) 8 51 7.0E-15 T 12-10-2018 IPR012454 Protein of unknown function DUF1659 NPD12_3000 8ca29ee2d0f871719d50defb1ba78325 98 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 9 91 2.7E-34 T 12-10-2018 IPR022477 Sporulation protein YqfC NPD12_3000 8ca29ee2d0f871719d50defb1ba78325 98 Pfam PF07873 YabP family 27 90 2.0E-14 T 12-10-2018 IPR022476 Sporulation protein YabP/YqfC NPD12_170 3bbfad310def63b000ebee37b1ae4995 87 Pfam PF10704 Protein of unknown function (DUF2508) 9 75 3.7E-15 T 12-10-2018 IPR019644 Protein of unknown function DUF2508 NPD12_2034 695caaaf433bcc9c0c08a612c7c75ccb 67 Gene3D G3DSA:3.40.50.300 2 65 5.4E-13 T 12-10-2018 NPD12_2034 695caaaf433bcc9c0c08a612c7c75ccb 67 SUPERFAMILY SSF52540 3 49 1.54E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2034 695caaaf433bcc9c0c08a612c7c75ccb 67 Pfam PF13238 AAA domain 6 59 3.3E-9 T 12-10-2018 NPD12_957 c9822c6d3e99f2561890ece1a6ede7b6 76 TIGRFAM TIGR04540 CLB_0814_fam: conserved hypothetical protein 2 74 4.9E-30 T 12-10-2018 IPR030902 Conserved hypothetical protein NPD12_757 c7f1ee7f195ed0837935181a4eda9a6e 34 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 33 2.7E-17 T 12-10-2018 IPR027601 Cys-rich peptide, Clo7bot family NPD12_1446 f59b363191b24218e573f510f93c7a6f 347 Pfam PF07355 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 1 347 5.4E-177 T 12-10-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 NPD12_1446 f59b363191b24218e573f510f93c7a6f 347 TIGRFAM TIGR01918 various_sel_PB: selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family 3 347 1.8E-174 T 12-10-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 NPD12_2045 e9efed2a24fcea9e818ef048d263bb06 281 Pfam PF01513 ATP-NAD kinase 23 257 3.6E-58 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 NPD12_2045 e9efed2a24fcea9e818ef048d263bb06 281 Hamap MF_00361 NAD kinase [nadK]. 2 273 31.667 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 NPD12_2045 e9efed2a24fcea9e818ef048d263bb06 281 SUPERFAMILY SSF111331 17 276 6.93E-80 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily NPD12_2045 e9efed2a24fcea9e818ef048d263bb06 281 Gene3D G3DSA:3.40.50.10330 25 273 7.1E-83 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 NPD12_2045 e9efed2a24fcea9e818ef048d263bb06 281 Gene3D G3DSA:2.60.200.30 116 250 7.1E-83 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 NPD12_271 469aa7d78758062f243872eba655cd74 78 Gene3D G3DSA:2.30.30.100 1 77 4.6E-24 T 12-10-2018 NPD12_271 469aa7d78758062f243872eba655cd74 78 PIRSF PIRSF037257 1 78 4.0E-32 T 12-10-2018 IPR009366 Protein Veg GO:0006355 NPD12_271 469aa7d78758062f243872eba655cd74 78 Pfam PF06257 Biofilm formation stimulator VEG 6 74 2.5E-29 T 12-10-2018 IPR009366 Protein Veg GO:0006355 NPD12_2157 c446d2550f4517f5389948467cec3422 135 Pfam PF11208 Protein of unknown function (DUF2992) 4 135 1.3E-51 T 12-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 NPD12_2157 c446d2550f4517f5389948467cec3422 135 PIRSF PIRSF021328 1 135 1.5E-46 T 12-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 NPD12_2168 3a80dfd153c76d760743be803b044c59 434 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 9 431 34.048 T 12-10-2018 IPR021144 Uncharacterised protein family UPF0597 NPD12_2168 3a80dfd153c76d760743be803b044c59 434 Pfam PF03313 Serine dehydratase alpha chain 190 426 4.6E-50 T 12-10-2018 IPR005130 Serine dehydratase-like, alpha subunit NPD12_2168 3a80dfd153c76d760743be803b044c59 434 PIRSF PIRSF006054 6 432 1.1E-129 T 12-10-2018 IPR021144 Uncharacterised protein family UPF0597 NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 SMART SM00418 38 116 8.3E-35 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 61 79 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 Gene3D G3DSA:1.10.10.10 4 121 1.1E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 SUPERFAMILY SSF46785 25 117 9.4E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 Pfam PF01022 Bacterial regulatory protein, arsR family 46 90 1.2E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 2.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 2.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 2.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_643 cf952ebf3e967774129c3ae01bc81552 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 NPD12_586 7b1fabd782a511350efd0be778b21585 240 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 56 183 1.3E-33 T 12-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 NPD12_586 7b1fabd782a511350efd0be778b21585 240 SMART SM00563 72 186 2.1E-34 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 NPD12_586 7b1fabd782a511350efd0be778b21585 240 SUPERFAMILY SSF69593 52 236 6.8E-43 T 12-10-2018 NPD12_586 7b1fabd782a511350efd0be778b21585 240 Pfam PF01553 Acyltransferase 59 183 4.5E-29 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 NPD12_1516 0a3a4fddde6b0bf3c97ed392e6dd0ec9 325 Pfam PF00454 Phosphatidylinositol 3- and 4-kinase 61 190 3.6E-6 T 12-10-2018 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain NPD12_898 be12ad7b77054285c33dd9ee23bb96d3 114 Gene3D G3DSA:3.40.50.300 8 92 1.3E-43 T 12-10-2018 NPD12_898 be12ad7b77054285c33dd9ee23bb96d3 114 SUPERFAMILY SSF52540 13 113 9.15E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_898 be12ad7b77054285c33dd9ee23bb96d3 114 Gene3D G3DSA:1.20.1580.10 93 114 1.3E-43 T 12-10-2018 NPD12_2859 eae40fcb1b7a3e12950dbe323b024bff 669 Gene3D G3DSA:2.60.40.10 54 158 4.4E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold NPD12_2859 eae40fcb1b7a3e12950dbe323b024bff 669 Pfam PF08329 Chitinase A, N-terminal domain 86 158 5.9E-6 T 12-10-2018 IPR013540 Chitinase A N-terminal GO:0004568|GO:0006032 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 NPD12_2859 eae40fcb1b7a3e12950dbe323b024bff 669 SUPERFAMILY SSF81296 60 158 5.32E-22 T 12-10-2018 IPR014756 Immunoglobulin E-set NPD12_1477 5fe0a54760cef9655b9a72876b99cbe8 109 SUPERFAMILY SSF101386 2 95 3.27E-20 T 12-10-2018 NPD12_1477 5fe0a54760cef9655b9a72876b99cbe8 109 PIRSF PIRSF006639 1 108 1.3E-34 T 12-10-2018 IPR011379 NTP Pyrophosphohydrolase MazG-related, GP37 NPD12_1477 5fe0a54760cef9655b9a72876b99cbe8 109 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 29 97 4.8E-14 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core NPD12_1477 5fe0a54760cef9655b9a72876b99cbe8 109 Gene3D G3DSA:1.10.287.1080 2 95 5.7E-16 T 12-10-2018 NPD12_2328 0338b5ad85c60a83aba300eae9939e32 137 SUPERFAMILY SSF54593 1 122 1.11E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_2328 0338b5ad85c60a83aba300eae9939e32 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 1.8E-9 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain NPD12_2328 0338b5ad85c60a83aba300eae9939e32 137 Gene3D G3DSA:3.10.180.10 1 136 1.3E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase NPD12_489 48c319d0284d1583558e2941e9677d37 231 Pfam PF04172 LrgB-like family 16 228 1.2E-78 T 12-10-2018 IPR007300 CidB/LrgB family NPD12_2100 6c4bcc2397075a0f87db99f0b49f2d41 227 Pfam PF00899 ThiF family 4 221 1.4E-45 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 NPD12_2100 6c4bcc2397075a0f87db99f0b49f2d41 227 SUPERFAMILY SSF69572 2 222 1.15E-64 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 NPD12_2100 6c4bcc2397075a0f87db99f0b49f2d41 227 Gene3D G3DSA:3.40.50.720 1 227 1.5E-56 T 12-10-2018 NPD12_2261 df3193176528152a16d04bdacfc2675d 414 SUPERFAMILY SSF103473 10 402 4.05E-51 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_2261 df3193176528152a16d04bdacfc2675d 414 Gene3D G3DSA:1.20.1250.20 5 404 2.3E-41 T 12-10-2018 NPD12_2261 df3193176528152a16d04bdacfc2675d 414 Pfam PF07690 Major Facilitator Superfamily 39 366 6.5E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_2076 b58a20217ecbead4bd0627edd4749fa8 357 SUPERFAMILY SSF69304 108 345 5.89E-15 T 12-10-2018 NPD12_103 bc725c0e91a1400bcfa024e270a841ec 334 Pfam PF09991 Predicted membrane protein (DUF2232) 19 313 5.2E-77 T 12-10-2018 IPR018710 Protein of unknown function DUF2232 NPD12_2832 42ec6f89b0f2588a02bd9835663dac7d 243 Gene3D G3DSA:3.20.20.370 23 236 2.0E-61 T 12-10-2018 NPD12_2832 42ec6f89b0f2588a02bd9835663dac7d 243 Pfam PF01522 Polysaccharide deacetylase 39 161 4.1E-29 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 NPD12_2832 42ec6f89b0f2588a02bd9835663dac7d 243 SUPERFAMILY SSF88713 39 228 1.14E-50 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 NPD12_735 c283c6414679178cacb480acf14b99aa 94 SUPERFAMILY SSF58104 12 91 2.35E-7 T 12-10-2018 NPD12_735 c283c6414679178cacb480acf14b99aa 94 Gene3D G3DSA:1.10.287.950 5 94 5.9E-8 T 12-10-2018 NPD12_2917 e5c8c6217cd88e07f028d5e1a2137dca 250 Pfam PF01925 Sulfite exporter TauE/SafE 8 243 3.2E-42 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_3454 e59990f4af3572f0087a1eb7e43109e5 385 Pfam PF04326 Putative DNA-binding domain 14 134 8.1E-25 T 12-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 NPD12_3454 e59990f4af3572f0087a1eb7e43109e5 385 Gene3D G3DSA:3.30.565.60 213 374 5.2E-10 T 12-10-2018 IPR038475 RecG, C-terminal domain superfamily NPD12_3454 e59990f4af3572f0087a1eb7e43109e5 385 Gene3D G3DSA:3.30.950.30 2 142 1.2E-29 T 12-10-2018 IPR038461 Schlafen, AAA domain superfamily NPD12_3791 7aeaf63894219cb126bc71ab301ee147 294 Pfam PF11041 Protein of unknown function (DUF2612) 74 113 1.3E-7 T 12-10-2018 IPR021283 Protein of unknown function DUF2612 NPD12_1174 0ff2075c18d22408935241932b0b2e38 179 Pfam PF01252 Signal peptidase (SPase) II 11 147 1.3E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 NPD12_3274 169807f75c2248d343398dfe8a85aed4 86 TIGRFAM TIGR03905 TIGR03905_4_Cys: uncharacterized protein TIGR03905 2 79 2.2E-43 T 12-10-2018 IPR023806 Conserved hypothetical protein CHP03905 NPD12_3274 169807f75c2248d343398dfe8a85aed4 86 Pfam PF12637 TSCPD domain 4 77 2.8E-32 T 12-10-2018 IPR024434 TSCPD domain NPD12_1445 07b6a780dc945cdd9d802f886ecb86d1 428 PIRSF PIRSF011588 1 428 2.9E-215 T 12-10-2018 IPR016585 Glycine/sarcosine/betaine reductase, component B, fused alpha/beta GO:0050485|GO:0055114 NPD12_1445 07b6a780dc945cdd9d802f886ecb86d1 428 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 1 426 1.9E-210 T 12-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 NPD12_1712 ecd53cbe13762013007f0f19ac1a4863 237 Pfam PF05949 Bacterial protein of unknown function (DUF881) 89 232 1.2E-34 T 12-10-2018 IPR010273 Protein of unknown function DUF881 NPD12_1712 ecd53cbe13762013007f0f19ac1a4863 237 Gene3D G3DSA:3.30.70.1880 88 237 4.0E-33 T 12-10-2018 NPD12_1158 edd13866910f478e60caf140fbc9f976 142 Pfam PF04657 Putative inner membrane exporter, YdcZ 7 137 4.8E-27 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_764 ea71fd0532df7a50c58fc88b0cc32f34 159 SUPERFAMILY SSF55729 1 151 2.48E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_764 ea71fd0532df7a50c58fc88b0cc32f34 159 Gene3D G3DSA:3.40.630.30 1 158 4.3E-14 T 12-10-2018 NPD12_764 ea71fd0532df7a50c58fc88b0cc32f34 159 Pfam PF00583 Acetyltransferase (GNAT) family 48 147 7.6E-6 T 12-10-2018 IPR000182 GNAT domain NPD12_528 d7eda00b20ac7208e2ec2b7ddc23f564 224 SUPERFAMILY SSF48317 12 194 2.35E-6 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily NPD12_528 d7eda00b20ac7208e2ec2b7ddc23f564 224 Pfam PF14378 PAP2 superfamily 51 190 3.1E-8 T 12-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 NPD12_1023 790797af15fe92a4c954275bb438e416 387 Pfam PF13786 Domain of unknown function (DUF4179) 35 136 2.1E-16 T 12-10-2018 IPR025436 Domain of unknown function DUF4179 NPD12_1895 d19bd6e253021067a7a7ebc8ae8a8212 183 Pfam PF11611 Domain of unknown function (DUF4352) 56 176 2.7E-27 T 12-10-2018 IPR029051 Domain of unknown function DUF4352 NPD12_1895 d19bd6e253021067a7a7ebc8ae8a8212 183 Gene3D G3DSA:2.60.40.1240 55 183 4.2E-30 T 12-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily NPD12_2545 e777cf54a2f4764225c2f607192002ea 116 Pfam PF03780 Asp23 family, cell envelope-related function 9 115 4.5E-34 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 NPD12_868 2b99cba6f5ecdecb3fdbc44163f1dd19 412 Gene3D G3DSA:3.40.50.1980 148 259 8.8E-28 T 12-10-2018 NPD12_868 2b99cba6f5ecdecb3fdbc44163f1dd19 412 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 14 406 5.1E-51 T 12-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 NPD12_868 2b99cba6f5ecdecb3fdbc44163f1dd19 412 Gene3D G3DSA:3.40.50.1980 11 147 6.8E-26 T 12-10-2018 NPD12_868 2b99cba6f5ecdecb3fdbc44163f1dd19 412 SUPERFAMILY SSF53807 10 410 1.8E-62 T 12-10-2018 NPD12_2736 9ead72658f6585ad72c1206d74225ad6 257 SUPERFAMILY SSF89550 1 199 3.73E-18 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 NPD12_2736 9ead72658f6585ad72c1206d74225ad6 257 PIRSF PIRSF016557 1 253 2.6E-82 T 12-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 NPD12_2736 9ead72658f6585ad72c1206d74225ad6 257 Gene3D G3DSA:3.20.20.140 1 257 5.3E-85 T 12-10-2018 NPD12_649 433460cd0e2ce0ef5f6eef921a1cff49 269 SUPERFAMILY SSF158430 131 262 3.4E-40 T 12-10-2018 NPD12_649 433460cd0e2ce0ef5f6eef921a1cff49 269 Gene3D G3DSA:1.20.1260.120 2 269 2.0E-89 T 12-10-2018 NPD12_649 433460cd0e2ce0ef5f6eef921a1cff49 269 SUPERFAMILY SSF158430 11 129 1.83E-35 T 12-10-2018 NPD12_649 433460cd0e2ce0ef5f6eef921a1cff49 269 Pfam PF11155 Domain of unknown function (DUF2935) 11 119 5.2E-26 T 12-10-2018 IPR021328 Protein of unknown function DUF2935 NPD12_649 433460cd0e2ce0ef5f6eef921a1cff49 269 Pfam PF11155 Domain of unknown function (DUF2935) 132 249 7.5E-33 T 12-10-2018 IPR021328 Protein of unknown function DUF2935 NPD12_1052 1be65d747f7ec67656330e9c7d15fa80 48 SUPERFAMILY SSF46955 3 24 3.11E-5 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily NPD12_3232 450a330c2793f5415edb42bc8141a90b 788 Pfam PF12392 Collagenase 376 492 4.3E-23 T 12-10-2018 IPR020988 Peptidase U32, collagenase NPD12_3232 450a330c2793f5415edb42bc8141a90b 788 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 NPD12_3232 450a330c2793f5415edb42bc8141a90b 788 Pfam PF01136 Peptidase family U32 76 298 1.8E-88 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 NPD12_3232 450a330c2793f5415edb42bc8141a90b 788 Pfam PF01136 Peptidase family U32 588 750 8.4E-13 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 NPD12_2879 ed88263c34d562393127020caa83f554 268 Pfam PF03609 PTS system sorbose-specific iic component 5 239 5.2E-70 T 12-10-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 NPD12_2656 07a5e730d3decbd0d1ff67b3c9b7e52d 245 Pfam PF09335 SNARE associated Golgi protein 76 193 1.6E-27 T 12-10-2018 IPR032816 SNARE associated Golgi protein NPD12_3333 7cc6137e0952026400564b38e216a573 311 SUPERFAMILY SSF69318 50 168 9.42E-6 T 12-10-2018 NPD12_662 a71e0f60ea2a7d02ca11e8a0068b0a5b 216 Pfam PF02163 Peptidase family M50 132 177 1.7E-7 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 NPD12_2329 cd3598f432d5a988f012c8b6dfdec5ea 462 Pfam PF02447 GntP family permease 11 461 1.5E-131 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 NPD12_2329 cd3598f432d5a988f012c8b6dfdec5ea 462 PIRSF PIRSF002746 6 462 5.2E-147 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 NPD12_2329 cd3598f432d5a988f012c8b6dfdec5ea 462 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 12 462 1.3E-107 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 NPD12_2267 b3c282c885bdbbf6f597a542388c7d6e 120 Pfam PF13788 Domain of unknown function (DUF4180) 9 116 3.0E-33 T 12-10-2018 IPR025438 Domain of unknown function DUF4180 NPD12_1513 f58f2e11912dbdef974608282b1b7bf2 84 Pfam PF10779 Haemolysin XhlA 13 78 4.4E-22 T 12-10-2018 IPR019715 Haemolysin XhlA NPD12_2637 dcc89b503fc0f68e0e1a70f4e4f602f5 397 Gene3D G3DSA:3.30.930.10 91 396 5.5E-80 T 12-10-2018 NPD12_2637 dcc89b503fc0f68e0e1a70f4e4f602f5 397 SUPERFAMILY SSF55681 94 373 4.15E-18 T 12-10-2018 NPD12_2637 dcc89b503fc0f68e0e1a70f4e4f602f5 397 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 199 370 7.8E-8 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 NPD12_2104 0a295364f3f5e607b19d49c7d3de63fa 146 Gene3D G3DSA:2.40.33.20 1 145 3.9E-32 T 12-10-2018 NPD12_2104 0a295364f3f5e607b19d49c7d3de63fa 146 SUPERFAMILY SSF50800 1 144 3.51E-38 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily NPD12_2287 e8cedb855324f64c627065b37a88e1d4 454 Pfam PF03611 PTS system sugar-specific permease component 11 405 4.8E-134 T 12-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 NPD12_1836 71fd06f2a414bffa3925922e629a493a 112 Pfam PF12788 YmaF family 10 104 4.4E-40 T 12-10-2018 IPR024307 YmaF NPD12_2975 9075abb3897bda6f1d3182133ff72842 114 Gene3D G3DSA:2.60.120.10 5 109 4.2E-38 T 12-10-2018 IPR014710 RmlC-like jelly roll fold NPD12_2975 9075abb3897bda6f1d3182133ff72842 114 Pfam PF07883 Cupin domain 44 110 8.0E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel NPD12_2975 9075abb3897bda6f1d3182133ff72842 114 SUPERFAMILY SSF51182 7 113 8.69E-27 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily NPD12_1815 9e2d54cd76106e2010641f26c544bd45 231 Pfam PF04143 Sulphur transport 66 225 9.5E-31 T 12-10-2018 IPR007272 Sulphur transport domain NPD12_1042 1b09654ea3c60954b99c3baa40c4e738 480 Gene3D G3DSA:3.40.50.1820 100 480 4.9E-141 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_1042 1b09654ea3c60954b99c3baa40c4e738 480 SUPERFAMILY SSF53474 102 469 3.45E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold NPD12_824 86a1f50a4fe1eb22cb23458a5b492696 105 Pfam PF09664 Protein of unknown function C-terminus (DUF2399) 1 99 6.2E-15 T 12-10-2018 IPR024465 Domain of unknown function DUF2399 NPD12_896 cefaa34bd6810cb198d6a8d3cebd9423 247 Pfam PF01061 ABC-2 type transporter 3 212 1.3E-27 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 NPD12_896 cefaa34bd6810cb198d6a8d3cebd9423 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 3.9E-10 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 NPD12_896 cefaa34bd6810cb198d6a8d3cebd9423 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 3.9E-10 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 NPD12_896 cefaa34bd6810cb198d6a8d3cebd9423 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 135 159 3.9E-10 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 NPD12_896 cefaa34bd6810cb198d6a8d3cebd9423 247 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 3.9E-10 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 NPD12_896 cefaa34bd6810cb198d6a8d3cebd9423 247 PIRSF PIRSF006648 4 247 5.0E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 NPD12_1786 5fccb297d7723e76ebf24f8162a88d21 146 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 135 6.6E-26 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_627 094ef979855d29a0ca876b005dd6961c 252 Pfam PF06738 Putative threonine/serine exporter 9 246 9.4E-70 T 12-10-2018 IPR010619 Putative threonine/serine exporter NPD12_2593 44aea8d27ce30f1582495c36eb774a44 222 TIGRFAM TIGR02271 TIGR02271: conserved domain 95 208 1.6E-30 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_2593 44aea8d27ce30f1582495c36eb774a44 222 Pfam PF09557 Domain of unknown function (DUF2382) 95 200 1.6E-26 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_838 ade4271fa690a895b0d7a40e4547b218 251 Gene3D G3DSA:1.20.120.520 76 251 1.3E-41 T 12-10-2018 NPD12_838 ade4271fa690a895b0d7a40e4547b218 251 Pfam PF04282 Family of unknown function (DUF438) 9 74 9.7E-21 T 12-10-2018 IPR007380 Domain of unknown function DUF438 NPD12_838 ade4271fa690a895b0d7a40e4547b218 251 Pfam PF01814 Hemerythrin HHE cation binding domain 84 220 2.9E-20 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 NPD12_822 cdfa4f73570e7ac38aacb98f8fb52b8e 564 Pfam PF08011 PD-(D/E)XK nuclease superfamily 453 560 8.4E-21 T 12-10-2018 IPR012547 PD-(D/E)XK nuclease superfamily 9 NPD12_822 cdfa4f73570e7ac38aacb98f8fb52b8e 564 Pfam PF09820 Predicted AAA-ATPase 5 299 1.2E-76 T 12-10-2018 IPR018631 AAA-ATPase-like domain NPD12_2644 acc455ffdb6c08f300097edcb83ceae3 89 Gene3D G3DSA:1.20.58.1000 3 89 3.7E-28 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily NPD12_2644 acc455ffdb6c08f300097edcb83ceae3 89 Pfam PF02583 Metal-sensitive transcriptional repressor 9 84 9.9E-26 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 NPD12_1467 895efdd34f03929b60417fdfa230c082 98 SUPERFAMILY SSF52980 5 85 3.49E-14 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 NPD12_1467 895efdd34f03929b60417fdfa230c082 98 SMART SM00990 2 84 3.6E-8 T 12-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 NPD12_1467 895efdd34f03929b60417fdfa230c082 98 Gene3D G3DSA:3.40.1350.10 1 95 1.5E-14 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 NPD12_556 fe3c938a97693f252e5887a524fb3bbd 274 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 16 139 1.9E-38 T 12-10-2018 IPR030910 SLAP domain, Bacillus-type NPD12_556 fe3c938a97693f252e5887a524fb3bbd 274 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 149 272 5.8E-38 T 12-10-2018 IPR030910 SLAP domain, Bacillus-type NPD12_1057 44f58fd5fffd0a9ad4e528a9b11452a6 290 SUPERFAMILY SSF54862 195 222 2.46E-5 T 12-10-2018 NPD12_958 e3523f6bdf36d510f22422366091290d 154 Pfam PF06695 Putative small multi-drug export protein 17 142 1.1E-43 T 12-10-2018 IPR009577 Putative small multi-drug export NPD12_3063 f3307a71e779d1dac5c197decb18a9b2 341 Pfam PF04245 37-kD nucleoid-associated bacterial protein 13 339 3.9E-62 T 12-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 NPD12_502 c4c23bdc6a3a27cf11b5b434e0202f3b 209 Pfam PF04647 Accessory gene regulator B 8 195 9.3E-40 T 12-10-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 NPD12_502 c4c23bdc6a3a27cf11b5b434e0202f3b 209 SMART SM00793 6 204 2.6E-18 T 12-10-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 NPD12_42 27c99caf3fc350966245312d3178786b 211 SUPERFAMILY SSF52218 1 196 5.74E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_42 27c99caf3fc350966245312d3178786b 211 Pfam PF03358 NADPH-dependent FMN reductase 1 156 1.7E-30 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 NPD12_42 27c99caf3fc350966245312d3178786b 211 Gene3D G3DSA:3.40.50.360 1 210 4.1E-38 T 12-10-2018 IPR029039 Flavoprotein-like superfamily NPD12_2903 4e1527ee9da0d3c5ff11c99d34d718ba 234 Pfam PF01841 Transglutaminase-like superfamily 25 132 1.6E-15 T 12-10-2018 IPR002931 Transglutaminase-like NPD12_2903 4e1527ee9da0d3c5ff11c99d34d718ba 234 SUPERFAMILY SSF54001 16 141 1.54E-20 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily NPD12_2903 4e1527ee9da0d3c5ff11c99d34d718ba 234 Gene3D G3DSA:3.10.620.30 1 142 1.2E-15 T 12-10-2018 NPD12_2117 c4517e1e6f186bb8c6e37e0e91cd59a3 485 Pfam PF12704 MacB-like periplasmic core domain 141 253 1.8E-9 T 12-10-2018 IPR025857 MacB-like periplasmic core domain NPD12_2117 c4517e1e6f186bb8c6e37e0e91cd59a3 485 Pfam PF02687 FtsX-like permease family 345 477 1.3E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_3813 fe6ffd85bfc32be2226bec9c267221ee 251 Gene3D G3DSA:1.10.10.10 9 99 9.3E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_2439 f4bc7251c4dcd83b9511cde89c7a3b4d 179 SUPERFAMILY SSF46934 4 46 4.93E-9 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 NPD12_2439 f4bc7251c4dcd83b9511cde89c7a3b4d 179 Gene3D G3DSA:1.10.8.10 1 47 5.6E-6 T 12-10-2018 NPD12_1270 c78653b5e101b25dcba3b1b3e1bc9f52 52 Pfam PF12669 Virus attachment protein p12 family 2 40 1.3E-11 T 12-10-2018 NPD12_210 eebfe9bcf10d5ca889039f10733804bb 70 Pfam PF10764 Inhibitor of sigma-G Gin 6 50 1.5E-16 T 12-10-2018 IPR019700 Anti-sigma-G factor Gin NPD12_2960 0e60eac349e0473c1da447b8d4c6bdf5 165 Gene3D G3DSA:3.30.450.40 10 163 6.3E-55 T 12-10-2018 IPR029016 GAF-like domain superfamily NPD12_2960 0e60eac349e0473c1da447b8d4c6bdf5 165 SUPERFAMILY SSF55781 6 161 1.81E-40 T 12-10-2018 NPD12_2960 0e60eac349e0473c1da447b8d4c6bdf5 165 Pfam PF13185 GAF domain 46 147 8.2E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 NPD12_190 96cf1c409fbbf4f0ae27b851483996a2 480 Pfam PF13786 Domain of unknown function (DUF4179) 56 145 1.9E-23 T 12-10-2018 IPR025436 Domain of unknown function DUF4179 NPD12_190 96cf1c409fbbf4f0ae27b851483996a2 480 Gene3D G3DSA:2.60.40.1630 86 226 2.2E-25 T 12-10-2018 NPD12_2376 0fe7a2d71cff2f77ae23875596b5e9a1 189 PIRSF PIRSF024534 1 166 2.3E-29 T 12-10-2018 IPR012652 Energy coupling factor transporter S component ThiW NPD12_2376 0fe7a2d71cff2f77ae23875596b5e9a1 189 Gene3D G3DSA:1.10.1760.20 1 169 1.2E-10 T 12-10-2018 NPD12_2376 0fe7a2d71cff2f77ae23875596b5e9a1 189 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 12 159 7.6E-40 T 12-10-2018 IPR012652 Energy coupling factor transporter S component ThiW NPD12_2376 0fe7a2d71cff2f77ae23875596b5e9a1 189 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 12 156 2.6E-47 T 12-10-2018 IPR012652 Energy coupling factor transporter S component ThiW NPD12_2727 40e403dde5b28cf82645980f32ea1701 305 Gene3D G3DSA:3.40.50.720 3 234 6.0E-104 T 12-10-2018 NPD12_2727 40e403dde5b28cf82645980f32ea1701 305 Gene3D G3DSA:3.90.25.10 172 298 6.0E-104 T 12-10-2018 NPD12_2727 40e403dde5b28cf82645980f32ea1701 305 SUPERFAMILY SSF51735 1 304 8.86E-91 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily NPD12_2727 40e403dde5b28cf82645980f32ea1701 305 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 295 6.3E-58 T 12-10-2018 IPR016040 NAD(P)-binding domain NPD12_1579 f421d0125cd35a8a463526b5e87ba07f 375 Pfam PF07907 YibE/F-like protein 131 368 1.2E-81 T 12-10-2018 IPR012507 YibE/F-like NPD12_1431 3a7e37298ac66bf1bb49c469e7784c77 75 Pfam PF13783 Domain of unknown function (DUF4177) 4 68 4.2E-8 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 NPD12_3495 361f2921effbd3848e4eea7411373ed1 402 Pfam PF12679 ABC-2 family transporter protein 2 401 7.4E-31 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_2449 8d6c05cc47d7b4a1a8e5de4bfac986c1 288 Gene3D G3DSA:1.10.357.140 15 164 1.7E-13 T 12-10-2018 NPD12_2449 8d6c05cc47d7b4a1a8e5de4bfac986c1 288 Pfam PF01040 UbiA prenyltransferase family 32 253 2.8E-23 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 NPD12_1892 023d9d846dec2d38d64c176e399264f3 93 Gene3D G3DSA:3.40.630.40 1 36 1.8E-6 T 12-10-2018 NPD12_1892 023d9d846dec2d38d64c176e399264f3 93 Gene3D G3DSA:2.30.30.40 55 93 5.0E-9 T 12-10-2018 NPD12_227 f831dbc0722637ce7ed15481a4df4e0b 191 Pfam PF07670 Nucleoside recognition 42 150 3.0E-12 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_2444 9d71d23dba6e6c504f16adb7abe22035 73 Pfam PF04070 Domain of unknown function (DUF378) 6 63 1.8E-19 T 12-10-2018 IPR007211 Protein of unknown function DUF378 NPD12_2448 10c50016f38245d12b368e7bf737ccf4 427 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 74 223 4.2E-6 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like NPD12_1787 3b4c38a07ca7bcde747bb0a0c241c5e1 141 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 137 3.2E-29 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_1619 18a3ebcdb0ef453fe87070f35a74846a 93 Pfam PF07870 Protein of unknown function (DUF1657) 8 55 9.6E-18 T 12-10-2018 IPR012452 Protein of unknown function DUF1657 NPD12_2418 dc3504f5930780182fc2fcceeb6ada12 92 Gene3D G3DSA:3.30.1450.10 1 59 1.7E-6 T 12-10-2018 IPR037873 BamE-like NPD12_2418 dc3504f5930780182fc2fcceeb6ada12 92 Pfam PF12978 Domain of Unknown Function with PDB structure (DUF3862) 2 88 2.3E-13 T 12-10-2018 IPR024418 Protein of unknown function DUF3862 NPD12_1627 6b96988f338f9fb42600bce884d1f083 262 SUPERFAMILY SSF81345 2 256 3.14E-30 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1627 6b96988f338f9fb42600bce884d1f083 262 Gene3D G3DSA:1.10.3470.10 35 262 7.7E-8 T 12-10-2018 IPR037294 ABC transporter, BtuC-like NPD12_1627 6b96988f338f9fb42600bce884d1f083 262 Pfam PF00950 ABC 3 transport family 3 258 1.8E-61 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 NPD12_1226 0e3eeea0413a0c3ccd387b0c69a9c123 75 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 3 70 2.8E-27 T 12-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like NPD12_1226 0e3eeea0413a0c3ccd387b0c69a9c123 75 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 75 28.42 T 12-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like NPD12_592 9326866ff691afcdece978c3e4735f18 71 Pfam PF04070 Domain of unknown function (DUF378) 2 59 2.6E-28 T 12-10-2018 IPR007211 Protein of unknown function DUF378 NPD12_1377 0d3ef8d3134d04b3aa677f7e48989e87 247 Pfam PF12730 ABC-2 family transporter protein 5 180 1.3E-11 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_1045 7b0debb7ab9aa974108652100fd404b3 151 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 147 4.7E-37 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_3521 79d6c6d40c04f607a970618bc62320bf 314 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 144 6.7E-31 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_3521 79d6c6d40c04f607a970618bc62320bf 314 Pfam PF04657 Putative inner membrane exporter, YdcZ 168 309 1.5E-37 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ NPD12_511 8507c0d6d8178fb058446b848911450e 196 Pfam PF12672 Protein of unknown function (DUF3793) 27 191 2.5E-40 T 12-10-2018 IPR024523 Protein of unknown function DUF3793 NPD12_1522 34b80f99e77806e9f4a6427c6b4eacbf 119 Pfam PF06305 Lipopolysaccharide assembly protein A domain 21 82 1.4E-11 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 NPD12_742 540f14c09c3adc92a95b20e146849083 109 Pfam PF14317 YcxB-like protein 29 91 6.3E-7 T 12-10-2018 IPR025588 YcxB-like protein NPD12_3547 d88458729fc62f40a0bd759bc207dbb6 300 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 21 231 9.0E-60 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT NPD12_3547 d88458729fc62f40a0bd759bc207dbb6 300 Gene3D G3DSA:3.30.70.120 208 283 7.0E-25 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal NPD12_3547 d88458729fc62f40a0bd759bc207dbb6 300 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 236 290 1.3E-21 T 12-10-2018 IPR019264 Domain of unknown function DUF2179 NPD12_3547 d88458729fc62f40a0bd759bc207dbb6 300 PIRSF PIRSF006483 8 297 3.0E-83 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT NPD12_823 8a811caa3e8e4263625f90e1f3861ef7 73 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 1 45 8.0E-7 T 12-10-2018 IPR024466 Conserved hypothetical protein CHP02679, N terminus NPD12_1007 4795ba7bbf10142ac3e3b506f93687db 248 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 248 41.502 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 NPD12_1007 4795ba7bbf10142ac3e3b506f93687db 248 Pfam PF02654 Cobalamin-5-phosphate synthase 12 243 5.2E-55 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 NPD12_1007 4795ba7bbf10142ac3e3b506f93687db 248 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 8 244 2.4E-46 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 NPD12_722 b3118f7d3ad3936df5c18861ae5b1508 547 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 376 495 1.7E-38 T 12-10-2018 IPR025299 CstA, C-terminal domain NPD12_722 b3118f7d3ad3936df5c18861ae5b1508 547 Pfam PF02554 Carbon starvation protein CstA 1 351 7.0E-126 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 NPD12_554 efd367f3ba39008ae38b5ebcab69ff97 483 PIRSF PIRSF006060 2 480 1.3E-89 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_554 efd367f3ba39008ae38b5ebcab69ff97 483 Gene3D G3DSA:1.20.1740.10 13 481 5.3E-74 T 12-10-2018 NPD12_554 efd367f3ba39008ae38b5ebcab69ff97 483 Pfam PF13520 Amino acid permease 23 440 1.4E-46 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 NPD12_2681 b286df353c09106cf69617fd8b129c3d 191 SUPERFAMILY SSF53335 34 111 1.65E-8 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase NPD12_2681 b286df353c09106cf69617fd8b129c3d 191 Gene3D G3DSA:3.40.50.150 22 180 1.3E-7 T 12-10-2018 NPD12_2059 d6d5b76d3789eb99dffa0b797962b494 65 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 2 65 6.4E-29 T 12-10-2018 IPR009570 Stage III sporulation protein AC NPD12_2059 d6d5b76d3789eb99dffa0b797962b494 65 Pfam PF06686 Stage III sporulation protein AC/AD protein family 7 62 1.4E-15 T 12-10-2018 IPR025664 Stage III sporulation protein AC/AD family NPD12_651 4ab07d8a79a86754fb4d7471db3728e9 334 Pfam PF09992 Phosphodiester glycosidase 149 332 4.5E-48 T 12-10-2018 IPR018711 Phosphodiester glycosidase NPD12_1458 57e5d2463263272bd908a8e86b9bbaed 138 Pfam PF06114 IrrE N-terminal-like domain 25 125 9.6E-15 T 12-10-2018 IPR010359 IrrE N-terminal-like domain NPD12_1458 57e5d2463263272bd908a8e86b9bbaed 138 Gene3D G3DSA:3.40.390.50 15 108 1.9E-5 T 12-10-2018 NPD12_2845 ba4553e8143a2925211498fd7b4fb8cc 373 Pfam PF12671 Putative amidase domain 209 368 7.2E-44 T 12-10-2018 IPR024301 Putative amidase domain NPD12_1991 8a2d73b25f4956c880a091da37d673c0 233 Pfam PF05857 TraX protein 5 229 1.8E-43 T 12-10-2018 IPR008875 TraX NPD12_2744 827aeaa7a28a1916d19b4b0e1ee10674 114 SUPERFAMILY SSF53756 1 82 1.38E-5 T 12-10-2018 NPD12_2744 827aeaa7a28a1916d19b4b0e1ee10674 114 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 1 95 2.8E-6 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 NPD12_2744 827aeaa7a28a1916d19b4b0e1ee10674 114 Gene3D G3DSA:3.40.50.2000 1 58 7.2E-17 T 12-10-2018 NPD12_2971 c8ee43ac00eea15af1448fbe0dffb50a 247 Pfam PF12837 4Fe-4S binding domain 5 28 1.5E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain NPD12_2971 c8ee43ac00eea15af1448fbe0dffb50a 247 SUPERFAMILY SSF54862 7 70 3.74E-17 T 12-10-2018 NPD12_2971 c8ee43ac00eea15af1448fbe0dffb50a 247 Gene3D G3DSA:3.30.70.20 4 63 6.0E-13 T 12-10-2018 NPD12_2730 db4dca74766d1477a0084634a165bbcb 389 Pfam PF04932 O-Antigen ligase 170 325 8.5E-7 T 12-10-2018 IPR007016 O-antigen ligase-related NPD12_3445 a1308e1b0021b8024fd6d24b7cb5bdf7 128 Pfam PF17032 zinc-ribbon family 23 123 3.8E-25 T 12-10-2018 IPR031493 Zinc-ribbon 15 NPD12_1560 a45f8a9bbd02d6d91a8759e766a2f1c6 315 Pfam PF02687 FtsX-like permease family 118 209 1.6E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 NPD12_2678 8e6e16dbe312f874ea1d5c2b3265d6c4 653 Pfam PF01496 V-type ATPase 116kDa subunit family 555 642 1.8E-9 T 12-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_2678 8e6e16dbe312f874ea1d5c2b3265d6c4 653 Pfam PF01496 V-type ATPase 116kDa subunit family 194 432 2.7E-19 T 12-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 NPD12_1687 cb00a130f37458a14c919d9afbc5653b 187 SUPERFAMILY SSF47240 66 184 2.92E-17 T 12-10-2018 IPR009078 Ferritin-like superfamily NPD12_1687 cb00a130f37458a14c919d9afbc5653b 187 Gene3D G3DSA:1.20.1260.10 58 186 4.8E-9 T 12-10-2018 IPR012347 Ferritin-like NPD12_1687 cb00a130f37458a14c919d9afbc5653b 187 Pfam PF13668 Ferritin-like domain 65 184 2.0E-5 T 12-10-2018 NPD12_2726 a1250b8875fd73134fc42a32d02f455f 476 Pfam PF13440 Polysaccharide biosynthesis protein 39 269 3.5E-8 T 12-10-2018 NPD12_3824 067f224df66f8a8dd7ed67edfde5225f 405 Pfam PF12671 Putative amidase domain 249 386 5.4E-28 T 12-10-2018 IPR024301 Putative amidase domain NPD12_291 1aaafc16b9b7cd0153727a2143d93c36 305 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 54 301 6.0E-88 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 NPD12_291 1aaafc16b9b7cd0153727a2143d93c36 305 Pfam PF07136 Protein of unknown function (DUF1385) 54 297 3.1E-92 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 NPD12_469 fd8254b733a3845a66a188480dcc6a5a 256 SUPERFAMILY SSF52540 3 225 4.11E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_469 fd8254b733a3845a66a188480dcc6a5a 256 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 NPD12_469 fd8254b733a3845a66a188480dcc6a5a 256 Pfam PF00005 ABC transporter 18 167 1.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 NPD12_469 fd8254b733a3845a66a188480dcc6a5a 256 Gene3D G3DSA:3.40.50.300 2 252 6.6E-65 T 12-10-2018 NPD12_469 fd8254b733a3845a66a188480dcc6a5a 256 SMART SM00382 27 212 1.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain NPD12_2594 43ed2092885c3a758e9028acdeefa296 157 Pfam PF09557 Domain of unknown function (DUF2382) 31 139 1.4E-29 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_2594 43ed2092885c3a758e9028acdeefa296 157 TIGRFAM TIGR02271 TIGR02271: conserved domain 31 144 2.7E-46 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_850 70b2565988844447254410c7cfee5b83 227 Gene3D G3DSA:3.30.200.20 49 110 1.0E-5 T 12-10-2018 NPD12_850 70b2565988844447254410c7cfee5b83 227 Gene3D G3DSA:1.10.510.10 77 172 1.0E-5 T 12-10-2018 NPD12_850 70b2565988844447254410c7cfee5b83 227 SUPERFAMILY SSF56112 49 186 4.89E-10 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily NPD12_280 a1ff4fa3313f08c89207facc0fba7f48 210 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 3 168 5.6E-68 T 12-10-2018 IPR014202 Sporulation stage II, protein R NPD12_280 a1ff4fa3313f08c89207facc0fba7f48 210 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 38 163 2.4E-52 T 12-10-2018 IPR014202 Sporulation stage II, protein R NPD12_2352 e9463534ccd2eb917a57b5812760aa5e 207 Gene3D G3DSA:2.60.40.1240 79 207 9.1E-30 T 12-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily NPD12_2352 e9463534ccd2eb917a57b5812760aa5e 207 Pfam PF11611 Domain of unknown function (DUF4352) 80 200 2.9E-27 T 12-10-2018 IPR029051 Domain of unknown function DUF4352 NPD12_1076 25bb30be9ed22db9e1dc1218286a417c 156 TIGRFAM TIGR02271 TIGR02271: conserved domain 30 143 3.6E-44 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_1076 25bb30be9ed22db9e1dc1218286a417c 156 Pfam PF09557 Domain of unknown function (DUF2382) 30 138 6.0E-29 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 NPD12_2908 d01fc390117b1ce38a64a4e764d0cc1c 421 SUPERFAMILY SSF52743 3 150 9.82E-19 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_2908 d01fc390117b1ce38a64a4e764d0cc1c 421 Gene3D G3DSA:3.40.50.200 1 234 3.4E-21 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 NPD12_1530 4c4aabffd7ad97ebf8c3ce1b70772282 159 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 34 110 1.5E-16 T 12-10-2018 IPR014229 Sporulation protein YtfJ NPD12_1466 7feeca1adcfac12784f317f1a91ad693 274 Pfam PF07083 Protein of unknown function (DUF1351) 9 216 2.6E-44 T 12-10-2018 IPR009785 Lactobacillus prophage Lj928, Orf309 NPD12_2906 073a011374609b83457cb263fea7eaac 162 Pfam PF13302 Acetyltransferase (GNAT) domain 8 141 1.8E-22 T 12-10-2018 IPR000182 GNAT domain NPD12_2906 073a011374609b83457cb263fea7eaac 162 SUPERFAMILY SSF55729 2 142 2.38E-31 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_2906 073a011374609b83457cb263fea7eaac 162 Gene3D G3DSA:3.40.630.30 2 157 2.7E-36 T 12-10-2018 NPD12_3122 35aba9142eafb34f4747b150090934b9 84 Pfam PF10779 Haemolysin XhlA 13 78 5.6E-23 T 12-10-2018 IPR019715 Haemolysin XhlA NPD12_559 513a39fda7ef2f92515887a5fc7930fa 183 Pfam PF02659 Putative manganese efflux pump 31 181 1.4E-31 T 12-10-2018 IPR003810 Putative manganese efflux pump NPD12_559 513a39fda7ef2f92515887a5fc7930fa 183 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 183 19.239 T 12-10-2018 IPR022929 Putative manganese efflux pump MntP NPD12_1225 577e2324b3ff8c67bebed7fc0ef924dc 266 SUPERFAMILY SSF55166 98 250 8.11E-37 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_1225 577e2324b3ff8c67bebed7fc0ef924dc 266 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 115 241 7.1E-42 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 NPD12_1225 577e2324b3ff8c67bebed7fc0ef924dc 266 Gene3D G3DSA:3.30.1380.10 42 263 1.1E-74 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 NPD12_3580 4c0be32dba8488c114e680bd464077e8 249 SUPERFAMILY SSF52518 12 239 8.96E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold NPD12_3580 4c0be32dba8488c114e680bd464077e8 249 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 209 3.9E-25 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 NPD12_3580 4c0be32dba8488c114e680bd464077e8 249 Gene3D G3DSA:3.40.50.970 74 239 4.9E-22 T 12-10-2018 NPD12_1009 9f6a2ea76f0582b031b5031d99dc33af 93 Pfam PF14898 Domain of unknown function (DUF4491) 2 92 2.4E-35 T 12-10-2018 IPR027890 Protein of unknown function DUF4491 NPD12_3365 0c000a38172fe1f6e2bfbbc6c5168a57 363 Pfam PF03773 Predicted permease 15 301 2.1E-53 T 12-10-2018 IPR005524 Predicted permease DUF318 NPD12_661 80e745c613dec871dbe178a4eb45b671 380 Gene3D G3DSA:3.40.1710.10 42 163 1.3E-5 T 12-10-2018 NPD12_661 80e745c613dec871dbe178a4eb45b671 380 Pfam PF12698 ABC-2 family transporter protein 21 367 2.7E-38 T 12-10-2018 NPD12_2791 fe82db7e3a0e20d7cee5b76d444a7f54 133 Pfam PF06949 Protein of unknown function (DUF1292) 69 132 2.2E-12 T 12-10-2018 IPR009711 Uncharacterised protein family UPF0473 NPD12_3136 e7b396479f54abfdee2b3fff19b6350f 361 SUPERFAMILY SSF69279 33 188 1.13E-7 T 12-10-2018 NPD12_498 fbef0c47b43c99dda936bc13e66a6c7e 169 Gene3D G3DSA:3.40.630.30 1 168 3.7E-25 T 12-10-2018 NPD12_498 fbef0c47b43c99dda936bc13e66a6c7e 169 Pfam PF13302 Acetyltransferase (GNAT) domain 14 146 5.4E-16 T 12-10-2018 IPR000182 GNAT domain NPD12_498 fbef0c47b43c99dda936bc13e66a6c7e 169 SUPERFAMILY SSF55729 4 155 2.9E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_3272 26d41a42a93b6c3c23040b4bcc7d3432 175 Pfam PF14277 Domain of unknown function (DUF4364) 11 169 3.6E-47 T 12-10-2018 IPR025374 Protein of unknown function DUF4364 NPD12_3272 26d41a42a93b6c3c23040b4bcc7d3432 175 Gene3D G3DSA:1.10.10.10 13 107 5.9E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily NPD12_880 671216adbdd16fb4f959cd81ddd710ef 175 Pfam PF00872 Transposase, Mutator family 1 59 5.0E-13 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 NPD12_1525 8dc8e0a957610fc9c2efb7d8b1e3b015 121 Pfam PF14276 Domain of unknown function (DUF4363) 12 112 1.7E-9 T 12-10-2018 IPR025373 Protein of unknown function DUF4363 NPD12_2512 9eec990863c6278c35ad90aa482198ab 148 Pfam PF07355 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 20 147 1.6E-14 T 12-10-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 NPD12_2405 62c2ce3c19c1ad5554002a6c20ea6539 248 Pfam PF12730 ABC-2 family transporter protein 5 177 1.0E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_1714 5355f85a871c466f9f74cd3a4b781744 243 Pfam PF05949 Bacterial protein of unknown function (DUF881) 91 237 5.5E-35 T 12-10-2018 IPR010273 Protein of unknown function DUF881 NPD12_1714 5355f85a871c466f9f74cd3a4b781744 243 Gene3D G3DSA:3.30.70.1880 89 243 1.9E-27 T 12-10-2018 NPD12_3258 60e3be049bf20e1bff0af46c1cf3b1bc 90 Gene3D G3DSA:1.10.8.910 20 72 1.8E-9 T 12-10-2018 IPR038300 SASP, alpha/beta-type superfamily NPD12_3258 60e3be049bf20e1bff0af46c1cf3b1bc 90 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 28 67 1.3E-9 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 NPD12_1663 9d4efc8c7d4b68483b25e31a67604fee 344 Pfam PF10974 Protein of unknown function (DUF2804) 22 343 7.6E-97 T 12-10-2018 IPR021243 Protein of unknown function DUF2804 NPD12_1503 fc6f2bcd46a65ba28ed7f5fc14ff833f 324 SUPERFAMILY SSF69279 34 132 3.68E-9 T 12-10-2018 NPD12_2806 a7b945d1e25ed853f177fe97bdbd3977 125 Pfam PF09682 Bacteriophage holin of superfamily 6 (Holin_LLH) 9 121 4.2E-6 T 12-10-2018 IPR010026 Phage holin, LL-H family NPD12_3769 ee4e5f060a4854dc1e12ffd4562291a2 310 Pfam PF04586 Caudovirus prohead serine protease 10 157 8.6E-19 T 12-10-2018 IPR006433 Prohead protease NPD12_2679 aa6d7d99848a3ee42e7dea67dfbbcc8a 108 SUPERFAMILY SSF81573 17 73 4.19E-6 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily NPD12_2374 34390155fd7c8666bb613a27857c8fff 130 TIGRFAM TIGR03987 TIGR03987: TIGR03987 family protein 5 129 1.3E-54 T 12-10-2018 IPR023813 Conserved hypothetical protein CHP03987 NPD12_2033 cdb3c9df565b39051a29e434ed40e8c4 105 SUPERFAMILY SSF52540 3 104 1.5E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_2033 cdb3c9df565b39051a29e434ed40e8c4 105 Gene3D G3DSA:3.40.50.300 1 105 7.8E-14 T 12-10-2018 NPD12_1029 f505dbb8788d5f7504bd6d498e5f9fe0 115 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 9 101 9.5E-13 T 12-10-2018 IPR023811 Conserved hypothetical protein CHP04076 NPD12_233 c6c9841fbead937c6ee191e8a81392f6 501 Pfam PF04286 Protein of unknown function (DUF445) 8 405 7.6E-46 T 12-10-2018 IPR007383 Protein of unknown function DUF445 NPD12_233 c6c9841fbead937c6ee191e8a81392f6 501 Pfam PF04286 Protein of unknown function (DUF445) 403 501 5.3E-21 T 12-10-2018 IPR007383 Protein of unknown function DUF445 NPD12_2211 839c58f257c45694f100fdd3cac8e3c2 97 Pfam PF14242 Domain of unknown function (DUF4342) 7 75 3.8E-18 T 12-10-2018 IPR025642 Domain of unknown function DUF4342 NPD12_1037 7903adc4942dc4e46287bdc06f2711f9 174 SUPERFAMILY SSF55729 41 174 1.59E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_1037 7903adc4942dc4e46287bdc06f2711f9 174 Pfam PF13673 Acetyltransferase (GNAT) domain 51 155 3.4E-12 T 12-10-2018 IPR000182 GNAT domain NPD12_1037 7903adc4942dc4e46287bdc06f2711f9 174 Gene3D G3DSA:3.40.630.30 17 156 4.7E-16 T 12-10-2018 NPD12_1364 683cc38bbb41d9fdc3ee5f3ec68dbcce 269 Pfam PF02535 ZIP Zinc transporter 107 264 1.3E-16 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 NPD12_3099 a96916deadbaa5ae60dc08dae172eb1c 283 SUPERFAMILY SSF54631 218 274 7.62E-5 T 12-10-2018 NPD12_1011 fc746b2a73d5b0c67c4a7d564fad898c 82 Pfam PF07875 Coat F domain 2 63 2.5E-21 T 12-10-2018 IPR012851 Spore coat protein CotF-like NPD12_1705 c77bfba9a022f717ac266f014c6f905e 167 Pfam PF04999 Cell division protein FtsL 57 128 1.3E-6 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 NPD12_2257 b1562b5f359f1952a1bd60238da355f8 370 SUPERFAMILY SSF103481 112 184 1.28E-6 T 12-10-2018 NPD12_1131 226b603f36334668b0b4b892e48f32ad 130 Pfam PF15592 Immunity protein 41 7 119 1.4E-19 T 12-10-2018 IPR028959 Immunity protein 41 NPD12_41 15fd1c1bdfa5458d016d505b69b13e39 408 Pfam PF07690 Major Facilitator Superfamily 38 336 1.0E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 NPD12_41 15fd1c1bdfa5458d016d505b69b13e39 408 SUPERFAMILY SSF103473 24 399 5.75E-54 T 12-10-2018 IPR036259 MFS transporter superfamily NPD12_41 15fd1c1bdfa5458d016d505b69b13e39 408 Gene3D G3DSA:1.20.1250.20 25 402 5.1E-46 T 12-10-2018 NPD12_3249 79a7f269992fd7c3035e2b70ba8e97d7 523 Pfam PF16962 Putative ABC exporter 1 521 6.9E-150 T 12-10-2018 IPR031584 Putative ABC exporter NPD12_2362 75f619720e1393a4f9602d02c7ebd6a4 151 Pfam PF13673 Acetyltransferase (GNAT) domain 27 146 2.6E-20 T 12-10-2018 IPR000182 GNAT domain NPD12_2362 75f619720e1393a4f9602d02c7ebd6a4 151 Gene3D G3DSA:3.40.630.30 1 145 2.2E-44 T 12-10-2018 NPD12_2362 75f619720e1393a4f9602d02c7ebd6a4 151 SUPERFAMILY SSF55729 2 147 2.33E-37 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase NPD12_428 0de587a9e95092769ac09e73eaab74ed 67 Pfam PF07870 Protein of unknown function (DUF1657) 8 55 2.8E-18 T 12-10-2018 IPR012452 Protein of unknown function DUF1657 NPD12_1332 578e6b491a928c13f1a6737013098767 193 Pfam PF12983 Protein of unknown function (DUF3867) 3 193 4.9E-77 T 12-10-2018 IPR024218 Protein of unknown function DUF3867 NPD12_2279 b05b8ef32721126284152bace469bf19 163 Pfam PF11188 Protein of unknown function (DUF2975) 37 162 6.3E-24 T 12-10-2018 IPR021354 Protein of unknown function DUF2975 NPD12_1379 a1966f25879b86bc81234daea8a091c3 54 Pfam PF12655 Domain of unknown function (DUF3787) 3 54 1.2E-28 T 12-10-2018 IPR024209 Protein of unknown function DUF3787 NPD12_1071 614e937014a1a61413af620ea3082900 203 SMART SM00871 57 202 2.0E-4 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding NPD12_1071 614e937014a1a61413af620ea3082900 203 Gene3D G3DSA:3.20.80.10 124 203 3.3E-9 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_1071 614e937014a1a61413af620ea3082900 203 SUPERFAMILY SSF55136 61 201 1.74E-18 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily NPD12_1008 078092ff01476913449be82735ed9444 261 Gene3D G3DSA:3.30.1330.10 2 127 2.7E-5 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily NPD12_527 f22c27a32463c1d2aeb570bf007e4456 336 Pfam PF03601 Conserved hypothetical protein 698 9 315 1.1E-86 T 12-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 NPD12_2115 431d749b021fd1dd9d10a3118d41887d 214 Pfam PF09335 SNARE associated Golgi protein 63 179 6.1E-20 T 12-10-2018 IPR032816 SNARE associated Golgi protein NPD12_1921 09c21f928fe6a22f3c5e2b23cec497cc 177 Pfam PF12671 Putative amidase domain 11 172 3.4E-32 T 12-10-2018 IPR024301 Putative amidase domain NPD12_2229 bec9b8e5e29d68f1e164fc1f3adc5478 389 Pfam PF13395 HNH endonuclease 256 307 1.7E-10 T 12-10-2018 IPR003615 HNH nuclease NPD12_2625 57156cdc949a77e05e773d5a25d26eaa 158 Pfam PF07833 Copper amine oxidase N-terminal domain 64 156 7.5E-14 T 12-10-2018 IPR012854 Copper amine oxidase-like, N-terminal NPD12_3039 8e1fffede08a050ad3ae46fbb1fadfb8 253 Pfam PF09851 Short C-terminal domain 224 251 4.2E-7 T 12-10-2018 IPR018649 SHOCT domain NPD12_2475 40e779f0c6c2da1cc14ce0539344e22d 326 Pfam PF01594 AI-2E family transporter 15 325 4.6E-34 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like NPD12_1717 085e64bd83c769b48a7c43dc433f58c9 91 Pfam PF02325 YGGT family 12 84 6.7E-19 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 NPD12_2786 51d2d188d7a050da52d754830edfebff 677 SMART SM01245 5 54 7.4E-13 T 12-10-2018 IPR032782 Jag, N-terminal NPD12_2786 51d2d188d7a050da52d754830edfebff 677 Pfam PF14804 Jag N-terminus 7 43 3.5E-9 T 12-10-2018 IPR032782 Jag, N-terminal NPD12_2786 51d2d188d7a050da52d754830edfebff 677 Pfam PF03961 Flagellar Assembly Protein A 161 648 7.9E-90 T 12-10-2018 IPR005646 Flagellar assembly protein A NPD12_2786 51d2d188d7a050da52d754830edfebff 677 Gene3D G3DSA:3.30.30.80 2 51 1.7E-6 T 12-10-2018 IPR038247 Jag, N-terminal domain superfamily NPD12_1616 25d0340e555d8bba5ffb2e0375aedc55 623 Pfam PF14342 Domain of unknown function (DUF4396) 466 619 8.4E-30 T 12-10-2018 IPR025509 Domain of unknown function DUF4396 NPD12_2212 80639af02e95e20385e62d011c56a3b8 97 Pfam PF14242 Domain of unknown function (DUF4342) 7 75 1.4E-18 T 12-10-2018 IPR025642 Domain of unknown function DUF4342 NPD12_2708 8ba1fe87430610834664f23fbc6288ff 145 Pfam PF02050 Flagellar FliJ protein 20 138 8.0E-22 T 12-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 NPD12_2708 8ba1fe87430610834664f23fbc6288ff 145 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 140 5.3E-22 T 12-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 NPD12_2347 9a217dbf5bcf4d4a4aa52f24fa40e4de 119 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 102 2.3E-21 T 12-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis NPD12_2347 9a217dbf5bcf4d4a4aa52f24fa40e4de 119 SUPERFAMILY SSF53146 1 114 2.62E-27 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily NPD12_2347 9a217dbf5bcf4d4a4aa52f24fa40e4de 119 Gene3D G3DSA:3.30.420.130 1 112 3.4E-29 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily NPD12_3711 58e3532911911ba24128ecdb62c3f787 125 Pfam PF13936 Helix-turn-helix domain 93 120 1.9E-6 T 12-10-2018 IPR025246 Transposase IS30-like HTH domain NPD12_3711 58e3532911911ba24128ecdb62c3f787 125 Gene3D G3DSA:1.10.10.60 84 122 7.3E-6 T 12-10-2018 NPD12_2706 f37c51a6f04c53e1589cf72369389e13 270 Pfam PF03963 Flagellar hook capping protein - N-terminal region 37 106 1.0E-20 T 12-10-2018 IPR005648 Flagellar hook capping protein NPD12_97 6017f83de959649165ff24d4747a3a41 71 Pfam PF11213 Protein of unknown function (DUF3006) 3 69 4.7E-21 T 12-10-2018 IPR021377 Protein of unknown function DUF3006 NPD12_2414 84acd2e2fb521d9663f1e10c7e631814 273 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 24 240 8.0E-59 T 12-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 NPD12_2414 84acd2e2fb521d9663f1e10c7e631814 273 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 249 39.653 T 12-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 NPD12_3318 765c4ba8c4d5fd7f66b308a5b04c6629 50 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 12 44 1.6E-4 T 12-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 NPD12_1969 ccc256f7d31cea6caf8fae8c1c4a4cd6 228 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 23 224 5.4E-33 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 NPD12_777 e1d105c22c6b3ecf165cdb29ab5c49aa 178 Pfam PF11193 Protein of unknown function (DUF2812) 16 114 8.0E-21 T 12-10-2018 IPR021359 Protein of unknown function DUF2812 NPD12_1996 db88ea0967d093e4d4b61ab8c55f3a23 49 Gene3D G3DSA:1.10.10.60 3 45 1.1E-6 T 12-10-2018 NPD12_1470 d10cb0668c59b1b9dcb39a99c155b52d 152 Pfam PF05037 Protein of unknown function (DUF669) 25 83 8.1E-10 T 12-10-2018 IPR007731 Protein of unknown function DUF669 NPD12_2353 c1df462630a15c195c8bb98465702f9a 113 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 55 105 9.0E-6 T 12-10-2018 IPR008792 Coenzyme PQQ synthesis D NPD12_2746 579f5f4e1682e27c0eeb6f880f637c48 66 Gene3D G3DSA:3.40.50.11190 2 57 4.1E-6 T 12-10-2018 NPD12_3036 2f8657cab085cd8ead689679ea8a73d4 324 SUPERFAMILY SSF69279 36 132 3.68E-9 T 12-10-2018 NPD12_2220 70d6471868250d1e91534086ab1cafcd 75 Pfam PF12395 Protein of unknown function 2 52 1.7E-6 T 12-10-2018 IPR022123 Protein of unknown function DUF3658 NPD12_1335 4b75ac014420815212e891ba4bd44009 367 Pfam PF01594 AI-2E family transporter 29 359 3.5E-66 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like NPD12_3247 0a959c26c451369b99b09dcd69bfdb0b 299 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 6 283 2.1E-73 T 12-10-2018 IPR014199 Sporulation protein YtxC NPD12_3247 0a959c26c451369b99b09dcd69bfdb0b 299 Pfam PF08812 YtxC-like family 67 282 2.3E-64 T 12-10-2018 IPR014199 Sporulation protein YtxC NPD12_2763 11a60c72f5f8291d52db88ff2c1f0786 599 Pfam PF01973 Protein of unknown function DUF115 197 362 3.8E-49 T 12-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like NPD12_3014 fdf7b0585a4efc539af7fb5ebd06ce4f 363 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 93 358 4.6E-82 T 12-10-2018 IPR010897 Sporulation stage II, protein P NPD12_3014 fdf7b0585a4efc539af7fb5ebd06ce4f 363 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 171 362 5.0E-73 T 12-10-2018 IPR010897 Sporulation stage II, protein P NPD12_901 3e3ffd7b9ed4de538d80f084357ad229 235 Pfam PF07505 Protein of unknown function (DUF5131) 3 213 3.9E-43 T 12-10-2018 IPR011101 Protein of unknown function DUF5131 NPD12_341 73eebde6e99f1fc913c4722f5390b767 284 Gene3D G3DSA:1.25.40.10 105 250 3.8E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 NPD12_341 73eebde6e99f1fc913c4722f5390b767 284 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 31 242 6.1E-79 T 12-10-2018 IPR018708 Protein of unknown function DUF2225 NPD12_2404 aaaa0fdd8b2da97183406003a264e5ba 244 Pfam PF12730 ABC-2 family transporter protein 5 172 9.4E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 NPD12_566 194d98c4cd97439dbb076b2a78cd11e0 351 Pfam PF06803 Protein of unknown function (DUF1232) 223 259 1.4E-13 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 NPD12_811 f39c29f128088944f049f852645bf9c3 94 Pfam PF14898 Domain of unknown function (DUF4491) 2 93 1.7E-40 T 12-10-2018 IPR027890 Protein of unknown function DUF4491 NPD12_2007 dcacd06563d018963841cd5d149021d0 170 Pfam PF11167 Protein of unknown function (DUF2953) 91 135 4.0E-11 T 12-10-2018 IPR021338 Protein of unknown function DUF2953 NPD12_228 298eae8cdc49ffdaaa2885c08b9db008 172 Pfam PF07670 Nucleoside recognition 43 143 7.7E-8 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 NPD12_2985 4ba6d2d3261fdf49a8c5e4e69101ea52 295 Pfam PF10882 Bacterial PH domain 64 162 1.4E-32 T 12-10-2018 IPR027783 Bacterial Pleckstrin homology domain-related NPD12_2985 4ba6d2d3261fdf49a8c5e4e69101ea52 295 ProDom PD076125 CPE2006 TRANSMEMBRANE MEMBRANE CAC1301 1 291 3.0E-67 T 12-10-2018 IPR020482 Uncharacterised protein family CAC1301 NPD12_2643 7daebd2ed2a85f36c64e6141ca9c8c05 162 Pfam PF12821 Threonine/Serine exporter, ThrE 6 134 4.5E-39 T 12-10-2018 IPR024528 Threonine/Serine exporter, ThrE NPD12_2749 aaa03e625a56a711fde8c0eb1b0db76a 113 Pfam PF01973 Protein of unknown function DUF115 2 105 1.0E-23 T 12-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like NPD12_848 7cb5faffd31e919924ea185703f45642 732 Pfam PF05569 BlaR1 peptidase M56 11 330 3.0E-54 T 12-10-2018 IPR008756 Peptidase M56 NPD12_3055 88249d98c62d82a75ca66bf2b0c69859 197 Pfam PF03592 Terminase small subunit 3 171 5.9E-35 T 12-10-2018 IPR005335 Terminase small subunit GO:0006323 NPD12_3055 88249d98c62d82a75ca66bf2b0c69859 197 Gene3D G3DSA:1.10.10.1400 1 66 1.9E-15 T 12-10-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily NPD12_2657 ce84a03846a95f7fd3ad9ef24fb78c6c 239 Pfam PF09335 SNARE associated Golgi protein 66 182 4.8E-32 T 12-10-2018 IPR032816 SNARE associated Golgi protein NPD12_2896 4f47c17abcf30b112a9c84071f7606e6 73 Pfam PF07872 Protein of unknown function (DUF1659) 8 49 1.0E-12 T 12-10-2018 IPR012454 Protein of unknown function DUF1659 NPD12_3727 394b771bf7be035493800d1242025936 783 SUPERFAMILY SSF52540 395 731 1.43E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase NPD12_3360 f69232c8dcb9eb13f57a93f79a7a6058 178 Gene3D G3DSA:3.40.190.10 31 111 1.0E-5 T 12-10-2018 NPD12_3360 f69232c8dcb9eb13f57a93f79a7a6058 178 Gene3D G3DSA:3.40.190.10 112 148 1.0E-5 T 12-10-2018 NPD12_2005 54539a54f788dd02c9478f88d0e31c5b 364 Pfam PF01594 AI-2E family transporter 27 356 5.6E-67 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like NPD12_1051 9327a62b2b5e511cc0c15d16820b7dd0 253 Pfam PF06738 Putative threonine/serine exporter 11 248 7.4E-61 T 12-10-2018 IPR010619 Putative threonine/serine exporter NPD12_3539 25e00893b2249dfeec75c129bfa77829 401 Pfam PF01098 Cell cycle protein 66 399 1.9E-81 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 NPD12_637 0b424b74837ce83664f927286a864799 153 Pfam PF11188 Protein of unknown function (DUF2975) 46 153 5.8E-16 T 12-10-2018 IPR021354 Protein of unknown function DUF2975 NPD12_2055 1ad0a039ad94ed3e9ef0c3d7770a0e89 198 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 20 197 5.4E-55 T 12-10-2018 IPR014195 Sporulation stage III, protein AG NPD12_1549 5f04089d3c24bb9bd3d2503f38104eb2 54 Pfam PF13451 Probable zinc-ribbon domain 3 48 3.8E-26 T 12-10-2018 IPR025306 Probable zinc-binding domain NPD12_1416 d87846cb509277abd31da3d4a1c1e6a5 53 Pfam PF11007 Spore coat associated protein JA (CotJA) 16 49 4.4E-14 T 12-10-2018 IPR020256 Spore coat protein CotJA NPD12_2510 e23883f05768646d4889090b1a2a1899 292 Pfam PF01925 Sulfite exporter TauE/SafE 5 148 5.2E-10 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_2510 e23883f05768646d4889090b1a2a1899 292 Pfam PF01925 Sulfite exporter TauE/SafE 172 285 3.7E-8 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 NPD12_2944 4ff6a554c1d8babbd6c7fb2bd24fd458 282 TIGRFAM TIGR03309 matur_yqeB: selenium-dependent molybdenum hydroxylase system protein, YqeB family 10 265 1.1E-124 T 12-10-2018 IPR017695 Selenium-dependent molybdenum hydroxylase system protein, YqeB family NPD12_115 c7bceadfbe9ce5e4d88402c6aaa2953b 81 Pfam PF03698 Uncharacterised protein family (UPF0180) 2 73 2.6E-12 T 12-10-2018 IPR005370 Uncharacterised protein family UPF0180 NPD12_465 0e4ec9fe0c7e65a56d569d60869f02c0 765 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 66 224 3.4E-46 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like NPD12_2611 3a2d04742e1420f02d1bf25bcf740cd0 342 Pfam PF01594 AI-2E family transporter 13 337 1.8E-63 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like NPD12_531 a804b368043ee7c853e8af9ada0de5ec 471 Pfam PF00474 Sodium:solute symporter family 32 426 4.8E-39 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 NPD12_531 a804b368043ee7c853e8af9ada0de5ec 471 Gene3D G3DSA:1.20.1730.10 20 471 1.1E-79 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily NPD12_2256 b433dd9fc73f7688529b49809fb6229f 88 SUPERFAMILY SSF46785 3 86 8.5E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily NPD12_2912 802a14292bb4fec46f1baf8dfa20708c 60 TIGRFAM TIGR04065 ocin_CLI_3235: putative bacteriocin precursor, CLI_3235 family 1 33 7.1E-18 T 12-10-2018 IPR023968 Bacteriocin precursor, CLI3235 family, putative NPD12_1508 2490ffac1cc3e3ea148d54520a5cfcc3 393 Pfam PF12571 Phage tail-collar fibre protein 1 150 5.9E-65 T 12-10-2018 IPR022225 Phage tail fibre protein NPD12_944 6825e6f8212a4b0ff1c2aa9a6092e219 750 Pfam PF06597 Clostridium P-47 protein 173 570 6.1E-38 T 12-10-2018 IPR010567 Clostridium P47 protein NPD12_1692 9da61e1f797f756b044ded3d78d13b56 221 Pfam PF03413 Peptidase propeptide and YPEB domain 149 213 2.5E-6 T 12-10-2018 IPR025711 PepSY domain NPD12_2507 3ba70891344a87472111b54957509c21 166 Pfam PF02620 Uncharacterized ACR, COG1399 56 162 2.0E-27 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD NPD12_743 fb79aabb44e1a493013d59030a01df21 109 Pfam PF14317 YcxB-like protein 29 91 5.3E-7 T 12-10-2018 IPR025588 YcxB-like protein NPD12_215 3a23dae9505d53391fb93951e31b9ac4 304 Pfam PF04468 PSP1 C-terminal conserved region 61 146 6.1E-34 T 12-10-2018 IPR007557 PSP1, C-terminal NPD12_929 3d52ca67a8d74a55f433471bca7b620f 75 Pfam PF11148 Protein of unknown function (DUF2922) 5 71 3.0E-22 T 12-10-2018 IPR021321 Protein of unknown function DUF2922 NPD12_488 1e7628d830e996e413f2ab53b17773b0 118 Pfam PF03788 LrgA family 14 106 2.1E-31 T 12-10-2018 IPR005538 LrgA/CidA family GO:0016021 NPD12_2747 3c08bf00bc6c912c36fd49c2d4bb163d 92 Gene3D G3DSA:3.40.50.11190 1 92 1.7E-14 T 12-10-2018 NPD12_1517 75d730c0d466e961d7c3f1d82b7de50c 290 Pfam PF11236 Protein of unknown function (DUF3037) 10 136 1.8E-8 T 12-10-2018 IPR021398 Protein of unknown function DUF3037 NPD12_522 69408c6fe12262f355e8005f5c9115ee 395 Pfam PF12671 Putative amidase domain 215 391 1.2E-46 T 12-10-2018 IPR024301 Putative amidase domain NPD12_825 7d6c6fdc65c8c1e6e5532d8b011fd4c5 213 Pfam PF02698 DUF218 domain 39 159 5.6E-26 T 12-10-2018 IPR003848 Domain of unknown function DUF218 NPD12_3710 6af666218eff27b70f0b53c6f1098e12 89 Pfam PF04977 Septum formation initiator 11 84 1.1E-19 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC NPD12_1494 783361c77f614fe0a804a1d3a2b62a4e 163 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 13 116 3.1E-27 T 12-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component NPD12_2083 a8c29a8a8b68c1f90067c9253e7d921a 113 Gene3D G3DSA:3.30.70.1990 29 113 3.2E-12 T 12-10-2018 NPD12_1531 c781086da0c1ab6e0d70f9ebe6c0ea61 181 Pfam PF11167 Protein of unknown function (DUF2953) 105 141 3.3E-5 T 12-10-2018 IPR021338 Protein of unknown function DUF2953