locus-tag	class	description
BBB49_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BBB49_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BBB49_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BBB49_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBB49_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBB49_00075	ENOG4108Z3G	3H domain protein
BBB49_00090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BBB49_00120	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BBB49_00125	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
BBB49_00130	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
BBB49_00145	ENOG4105BZU	Histidine kinase
BBB49_00160	ENOG4105DJ4	phosphatidylserine decarboxylase
BBB49_00165	ENOG4108IG5	Transcriptional regulator
BBB49_00175	ENOG4105J7I	hydrolase
BBB49_00180	ENOG4105C5H	ABC transporter
BBB49_00195	ENOG4108UT2	hemolysin iii
BBB49_00200	ENOG4105DWD	nucleoside recognition domain protein
BBB49_00210	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BBB49_00220	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_00240	ENOG4105CPI	Metal Dependent Phosphohydrolase
BBB49_00245	ENOG4105C5F	glutamine synthetase
BBB49_00255	ENOG4107ZE5	PPIases accelerate the folding of proteins
BBB49_00270	ENOG41069ER	domain protein
BBB49_00290	ENOG4108K88	Membrane
BBB49_00295	ENOG4105N5T	Radical SAM Protein
BBB49_00300	ENOG4108N5B	2-phosphosulfolactate phosphatase
BBB49_00320	ENOG4108STX	response regulator
BBB49_00325	ENOG4105US7	Histidine kinase
BBB49_00365	ENOG4105UQX	Mate efflux family protein
BBB49_00375	ENOG4108JIC	nucleoside recognition domain protein
BBB49_00385	ENOG4107RAQ	aminopeptidase
BBB49_00390	ENOG4107S6Z	Na H antiporter
BBB49_00405	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BBB49_00410	ENOG4105F8V	Hydrolase, tatD family
BBB49_00415	ENOG41069ER	domain protein
BBB49_00420	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
BBB49_00425	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BBB49_00455	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
BBB49_00470	ENOG4105EPR	degv family
BBB49_00475	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BBB49_00480	ENOG4107SDT	Homocitrate synthase
BBB49_00485	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BBB49_00490	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
BBB49_00500	ENOG4108VX5	3-methyladenine DNA glycosylase
BBB49_00520	ENOG4105DFU	Cell wall formation (By similarity)
BBB49_00525	ENOG4105DFT	pur operon repressor
BBB49_00530	ENOG4105K4W	Could be involved in septation (By similarity)
BBB49_00535	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BBB49_00545	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_00550	ENOG4105BZU	Histidine kinase
BBB49_00555	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BBB49_00560	ENOG4108JA2	transcriptioN-repair coupling factor
BBB49_00570	ENOG4108M14	stage v sporulation protein t
BBB49_00580	ENOG4108IY2	MazG family
BBB49_00590	ENOG41082I2	s4 domain protein
BBB49_00610	ENOG41060GV	RNA binding s1 domain protein
BBB49_00670	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BBB49_00675	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BBB49_00680	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BBB49_00685	ENOG4105CKU	formyltetrahydrofolate synthetase
BBB49_00690	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BBB49_00695	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BBB49_00700	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BBB49_00705	ENOG4105CRK	lysyL-tRNA synthetase
BBB49_00730	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
BBB49_00735	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BBB49_00795	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BBB49_00800	ENOG4105X0R	protein from nitrogen regulatory protein P-II
BBB49_00810	ENOG4105MA4	psp1 domain protein
BBB49_00820	ENOG41084EF	Ferredoxin
BBB49_00825	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
BBB49_00835	ENOG4108Z0C	Uvrb UvrC protein
BBB49_00865	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BBB49_00870	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
BBB49_00880	ENOG4105CTP	PilT protein domain protein
BBB49_00885	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BBB49_00890	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BBB49_00895	ENOG4105C8N	cysteinyl-tRNA synthetase
BBB49_00900	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BBB49_00905	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BBB49_00915	ENOG4105QIV	RNA polymerase
BBB49_00925	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BBB49_00930	ENOG4105WDJ	50S ribosomal protein L33
BBB49_00935	ENOG410683Z	Preprotein translocase SecE subunit
BBB49_00940	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BBB49_00945	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BBB49_00950	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BBB49_00960	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BBB49_00970	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BBB49_00985	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BBB49_00990	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BBB49_00995	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BBB49_01000	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BBB49_01005	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BBB49_01010	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BBB49_01015	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBB49_01020	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BBB49_01025	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BBB49_01030	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BBB49_01035	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BBB49_01040	ENOG41082SA	50s ribosomal protein l29
BBB49_01045	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BBB49_01050	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BBB49_01055	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BBB49_01060	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBB49_01070	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BBB49_01075	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BBB49_01080	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BBB49_01085	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BBB49_01090	ENOG41084RK	50S ribosomal protein L30
BBB49_01095	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BBB49_01100	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BBB49_01105	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BBB49_01120	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BBB49_01130	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBB49_01135	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BBB49_01140	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BBB49_01145	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BBB49_01150	ENOG4108ZT0	50S ribosomal protein l17
BBB49_01155	ENOG4108JJB	ABC transporter
BBB49_01160	ENOG4108JJB	ABC transporter
BBB49_01165	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BBB49_01170	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BBB49_01175	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BBB49_01185	ENOG4105EAM	Na Pi-cotransporter
BBB49_01190	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BBB49_01195	ENOG4107GFK	fumarate
BBB49_01205	ENOG4107AYK	membrAne
BBB49_01225	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BBB49_01230	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BBB49_01235	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BBB49_01245	ENOG4105DYB	Isoaspartyl dipeptidase
BBB49_01255	ENOG4105C8B	TIGR00159 family
BBB49_01265	ENOG4105DZ0	fad dependent oxidoreductase
BBB49_01270	ENOG4107RE7	phosphate butyryltransferase
BBB49_01290	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_01295	ENOG4105C3S	Mate efflux family protein
BBB49_01300	ENOG4105NA0	Transcriptional regulator
BBB49_01320	ENOG4105KGF	protein, YerC YecD
BBB49_01325	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BBB49_01335	ENOG4108ZP8	Acetolactate synthase small subunit
BBB49_01340	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BBB49_01345	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BBB49_01350	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BBB49_01355	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BBB49_01365	ENOG4105C7K	acetolactate synthase
BBB49_01390	ENOG4108IUJ	4-alpha-glucanotransferase
BBB49_01395	ENOG4105FKQ	transcriptional regulator
BBB49_01405	ENOG4105CI1	PTS System
BBB49_01445	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BBB49_01450	ENOG4105E98	transcriptional regulator DeoR family
BBB49_01465	ENOG4105DT3	PTS system, galactitol-specific IIc component
BBB49_01470	ENOG4105RSI	Galactose-6-phosphate isomerase subunit LacA
BBB49_01480	ENOG4105D2N	Aldolase
BBB49_01485	ENOG4105DE4	1-phosphofructokinase
BBB49_01495	ENOG4108V2W	Carbonate dehydratase
BBB49_01500	ENOG4105D07	Signal peptide peptidase, SppA
BBB49_01515	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
BBB49_01520	ENOG410874W	AraC family transcriptional regulator
BBB49_01525	ENOG4108IUK	alpha amylase, catalytic
BBB49_01530	ENOG4108QTI	)-transporter
BBB49_01540	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BBB49_01575	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BBB49_01585	ENOG4107BJW	polysaccharide deacetylase
BBB49_01595	ENOG4107QW8	radical SAM domain protein
BBB49_01605	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BBB49_01610	ENOG4105BZJ	Electron transfer flavoprotein
BBB49_01615	ENOG4105C10	Electron transfer flavoprotein
BBB49_01620	ENOG4105CQB	FAD linked oxidase domain protein
BBB49_01625	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BBB49_01640	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BBB49_01645	ENOG4105BZU	Histidine kinase
BBB49_01660	ENOG4105CXY	transporter
BBB49_01665	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
BBB49_01670	ENOG4108X79	transcriptional regulator
BBB49_01675	ENOG4105CE4	GlcNAc 6-P deacetylase
BBB49_01680	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BBB49_01685	ENOG4105VZJ	PTS System
BBB49_01690	ENOG4105VCP	PTS System
BBB49_01695	ENOG4105RD7	BadF BadG BcrA BcrD
BBB49_01705	ENOG4105CK1	PTS System
BBB49_01720	ENOG4105C59	p-type ATPase
BBB49_01725	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
BBB49_01730	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
BBB49_01735	ENOG4105E39	Enoyl-CoA hydratase
BBB49_01740	ENOG4105C1G	acyl-Coa dehydrogenase
BBB49_01745	ENOG4105BZJ	Electron transfer flavoprotein
BBB49_01755	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BBB49_01775	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BBB49_01780	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BBB49_01790	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BBB49_01805	ENOG4105JVQ	RNA Polymerase
BBB49_01830	ENOG4107QYV	phosphohexose isomerase
BBB49_01845	ENOG4105E4C	Lytic transglycosylase catalytic
BBB49_01860	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BBB49_01890	ENOG4105DIB	Oligopeptide-binding protein
BBB49_02010	ENOG4105W4W	Transcriptional regulator
BBB49_02015	ENOG4105D56	permease protein
BBB49_02025	ENOG4105CT8	Phosphorylase
BBB49_02030	ENOG4108JP0	extracellular solute-binding protein family 1
BBB49_02035	ENOG4105RD7	BadF BadG BcrA BcrD
BBB49_02040	ENOG4105CE4	GlcNAc 6-P deacetylase
BBB49_02045	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
BBB49_02050	ENOG4105ETZ	PTS System
BBB49_02055	ENOG4105F3R	pts system mannose fructose sorbose family iid
BBB49_02060	ENOG4108X79	transcriptional regulator
BBB49_02065	ENOG4105E70	isomerase
BBB49_02075	ENOG4105D2N	Aldolase
BBB49_02115	ENOG4105C9K	Endothelin-converting enzyme 1
BBB49_02150	ENOG4105JVQ	RNA Polymerase
BBB49_02155	ENOG4108P49	AntiSigma factor
BBB49_02160	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BBB49_02165	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BBB49_02175	ENOG4105C3M	thioredoxin reductase
BBB49_02190	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BBB49_02200	ENOG4105C0H	protease
BBB49_02205	ENOG4105VCP	PTS System
BBB49_02220	ENOG4108TJN	glycosyl transferase group 1
BBB49_02240	ENOG4108TJN	glycosyl transferase group 1
BBB49_02250	ENOG4105XFA	sporulation peptidase YabG
BBB49_02255	ENOG4105W42	Veg protein
BBB49_02275	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BBB49_02280	ENOG4108ZXQ	stage ii sporulation protein r
BBB49_02300	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BBB49_02305	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BBB49_02310	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
BBB49_02315	ENOG41082DI	50s ribosomal protein l31
BBB49_02320	ENOG4107104	thymidine kinase
BBB49_02330	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BBB49_02340	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BBB49_02345	ENOG4108YZG	isomerase
BBB49_02350	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BBB49_02360	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BBB49_02365	ENOG4105CHU	acetyl-coa acetyltransferase
BBB49_02380	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
BBB49_02385	ENOG41082I9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BBB49_02390	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
BBB49_02410	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BBB49_02425	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BBB49_02440	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
BBB49_02450	ENOG4108ZDA	Sporulation protein YyaC
BBB49_02515	ENOG4105C7H	Helicase, RecD TraA family
BBB49_02525	ENOG4105MJ2	Competence protein
BBB49_02530	ENOG4105MS2	ribosomal subunit Interface protein
BBB49_02535	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BBB49_02540	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BBB49_02560	ENOG4105BZU	Histidine kinase
BBB49_02585	ENOG410801F	ribosomal-protein-alanine acetyltransferase
BBB49_02590	ENOG41072GX	Peptidase M22 Glycoprotease
BBB49_02595	ENOG4105K8N	protein family UPF0079, ATPase
BBB49_02620	ENOG4105KME	endoribonuclease L-psp
BBB49_02655	ENOG4105DSE	periplasmic solute binding protein
BBB49_02665	ENOG4106I4J	membrane
BBB49_02670	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BBB49_02685	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BBB49_02695	ENOG4105CIN	aminoacyl-histidine dipeptidase
BBB49_02710	ENOG4108Z03	MAF-like protein
BBB49_02715	ENOG4105W5Q	DNA repair protein (RadC
BBB49_02720	ENOG4105DFF	Rod shape-determining protein mreb
BBB49_02725	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BBB49_02740	ENOG4105PW4	Sugar fermentation stimulation protein homolog
BBB49_02750	ENOG4107QMS	site-determining protein
BBB49_02755	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BBB49_02760	ENOG4105CNI	cell division protein FtsW
BBB49_02790	ENOG4105C03	ribonuclease
BBB49_02795	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BBB49_02805	ENOG4105K46	50S ribosomal protein l27
BBB49_02810	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBB49_02815	ENOG410812S	Rna-binding protein
BBB49_02820	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BBB49_02825	ENOG4108WF2	Metal Dependent Phosphohydrolase
BBB49_02830	ENOG4108KGH	TRANSCRIPTIONal
BBB49_02835	ENOG4105EMS	pseudouridine synthase
BBB49_02840	ENOG4105DZ1	carboxypeptidase
BBB49_02845	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
BBB49_02875	ENOG4105CNI	cell division protein FtsW
BBB49_02885	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
BBB49_02895	ENOG41090R9	glycosyltransferase
BBB49_02900	ENOG4107R51	Glycosyl transferase, family 2
BBB49_02905	ENOG41090R9	glycosyltransferase
BBB49_02915	ENOG4107ZE5	PPIases accelerate the folding of proteins
BBB49_02920	ENOG4105CYN	Serine protein kinase
BBB49_02925	ENOG4106AKX	UPF0229 protein
BBB49_02930	ENOG4105ED1	spovr family
BBB49_02935	ENOG4108RAC	Rubrerythrin
BBB49_02950	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BBB49_02955	ENOG4105CBD	Diacylglycerol kinase
BBB49_02975	ENOG4105CJW	magnesium transporter
BBB49_02980	ENOG4105C6T	cysteine synthase
BBB49_02985	ENOG4105D7W	serine acetyltransferase
BBB49_02990	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BBB49_03000	ENOG4105CSM	endonuclease III
BBB49_03005	ENOG4105CPF	Cell wall formation (By similarity)
BBB49_03015	ENOG4105BZU	Histidine kinase
BBB49_03025	ENOG41073R8	VanW family
BBB49_03030	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BBB49_03040	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBB49_03050	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BBB49_03055	ENOG4105BZA	Phosphoglycerate kinase
BBB49_03060	ENOG4105CP7	Triose-phosphate isomerase
BBB49_03065	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BBB49_03080	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BBB49_03090	ENOG4105KAF	membrAne
BBB49_03100	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BBB49_03110	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BBB49_03115	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BBB49_03120	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BBB49_03125	ENOG4108UMI	ABC transporter, permease
BBB49_03130	ENOG4105D01	(LipO)protein
BBB49_03165	ENOG4105CMT	Dihydroxyacetone kinase
BBB49_03200	ENOG4105C08	Histidine kinase
BBB49_03205	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BBB49_03215	ENOG4105FH5	Membrane
BBB49_03225	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BBB49_03235	ENOG4105BZU	Histidine kinase
BBB49_03250	ENOG4105C2W	permease
BBB49_03255	ENOG4105BZU	Histidine kinase
BBB49_03265	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BBB49_03270	ENOG4105C5H	ABC transporter
BBB49_03290	ENOG4105C9B	Cysteine desulfurase
BBB49_03295	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
BBB49_03300	ENOG41081WW	Probably functions as a manganese efflux pump (By similarity)
BBB49_03305	ENOG4105I3K	Ferric uptake regulator, Fur family
BBB49_03310	ENOG4105FAV	ABC, transporter
BBB49_03315	ENOG4105FDK	ABC transporter
BBB49_03320	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
BBB49_03330	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
BBB49_03335	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
BBB49_03350	ENOG4105DPN	Oligoendopeptidase f
BBB49_03355	ENOG4107ZXI	Rhomboid family
BBB49_03365	ENOG4105D82	Glutamate dehydrogenase
BBB49_03375	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBB49_03380	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BBB49_03390	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BBB49_03395	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BBB49_03400	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BBB49_03415	ENOG4105CHM	Aminotransferase
BBB49_03425	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BBB49_03435	ENOG4108V3W	Chemotaxis protein, CheW
BBB49_03445	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BBB49_03450	ENOG4105BZU	Histidine kinase
BBB49_03455	ENOG4105CBS	Chea signal transduction histidine kinase
BBB49_03460	ENOG4107PHP	CheC --inhibitor of MCP methylation
BBB49_03465	ENOG4107YTP	response regulator receiver protein
BBB49_03470	ENOG4108V3W	Chemotaxis protein, CheW
BBB49_03475	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BBB49_03480	ENOG4105DD5	Flagellar motor switch protein
BBB49_03500	ENOG4105E1Q	flagellar hook-associated protein
BBB49_03505	ENOG4105DTJ	flagellar hook-associated protein
BBB49_03510	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
BBB49_03515	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BBB49_03535	ENOG4107RT6	flagellar hook-associated
BBB49_03555	ENOG4105I03	Flagellin
BBB49_03560	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
BBB49_03565	ENOG4108ZC9	flagellar basal-body rod protein flgc
BBB49_03570	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BBB49_03575	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BBB49_03580	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BBB49_03615	ENOG4108JQA	flagellar
BBB49_03620	ENOG4108JQA	flagellar
BBB49_03625	ENOG41068WV	flagellar FlbD family protein
BBB49_03630	ENOG4105E14	MotA TolQ exbB proton channel
BBB49_03635	ENOG4106VK6	Flagellar motor protein
BBB49_03650	ENOG4105CN7	Flagellar biosynthetic protein FliP
BBB49_03660	ENOG4105D00	flagellar biosynthetic protein flhB
BBB49_03665	ENOG4105D7B	Flagellar biosynthesis protein flha
BBB49_03670	ENOG4105FZW	flagellar biosynthesis regulator FlhF
BBB49_03685	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBB49_03695	ENOG4105CGA	flagellar basal-body rod protein FlgG
BBB49_03700	ENOG4105CGA	flagellar basal-body rod protein FlgG
BBB49_03730	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BBB49_03735	ENOG4105DAN	ATP-dependent protease
BBB49_03740	ENOG41082AN	stage II sporulation protein
BBB49_03745	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
BBB49_03750	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBB49_03755	ENOG41090VF	Stage v sporulation protein ac
BBB49_03760	ENOG4105CZ3	stage V sporulation protein ad
BBB49_03770	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBB49_03785	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BBB49_03790	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
BBB49_03815	ENOG4105CSA	Coproporphyrinogen iii oxidase
BBB49_03820	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BBB49_03825	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBB49_03830	ENOG4105CFG	Acts as a chaperone (By similarity)
BBB49_03835	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BBB49_03850	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BBB49_03860	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BBB49_03865	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BBB49_03870	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BBB49_03875	ENOG4107YU2	histidine triad (hIT) protein
BBB49_03885	ENOG4105KTH	gatB Yqey
BBB49_03900	ENOG4105CTJ	Metal Dependent Phosphohydrolase
BBB49_03910	ENOG4107YR5	Diacylglycerol kinase
BBB49_03915	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BBB49_03935	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BBB49_03945	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BBB49_03950	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BBB49_03955	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBB49_03990	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
BBB49_03995	ENOG4105ETE	Transcriptional regulator (LacI family
BBB49_04000	ENOG4108IUJ	4-alpha-glucanotransferase
BBB49_04010	ENOG4105C5I	Dehydrogenase
BBB49_04015	ENOG4105DCG	PHP domain protein
BBB49_04055	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBB49_04075	ENOG4105BZ8	glutamate synthase
BBB49_04085	ENOG4105K63	Thioredoxin
BBB49_04090	ENOG4105K56	Transcriptional regulator
BBB49_04120	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
BBB49_04125	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_04140	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
BBB49_04150	ENOG4105CZV	ABC transporter
BBB49_04155	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
BBB49_04160	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BBB49_04170	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BBB49_04175	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BBB49_04200	ENOG4108ZJ4	polysaccharide deacetylase
BBB49_04235	ENOG4105C19	ABC transporter
BBB49_04245	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BBB49_04260	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
BBB49_04265	ENOG4108J6I	peptidase, M16
BBB49_04270	ENOG4105CXN	decarboxylase
BBB49_04275	ENOG4105C8J	)-transporter
BBB49_04280	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BBB49_04285	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BBB49_04295	ENOG4108ZB6	transcriptional regulator AsnC family
BBB49_04300	ENOG4105CHM	Aminotransferase
BBB49_04305	ENOG4105ETE	Transcriptional regulator (LacI family
BBB49_04310	ENOG4107TFB	basic membrane
BBB49_04315	ENOG4108JQ9	ABC transporter
BBB49_04320	ENOG4105UIB	(ABC) transporter
BBB49_04330	ENOG4105KG3	cytidine deaminase
BBB49_04335	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
BBB49_04350	ENOG4105DHT	Metal Dependent Phosphohydrolase
BBB49_04355	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BBB49_04360	ENOG4105DQ6	Transposase
BBB49_04365	ENOG4108EUD	Lysophospholipase
BBB49_04370	ENOG41080E8	Transcriptional regulator, Spx MgsR family
BBB49_04375	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
BBB49_04380	ENOG4105CAH	Chromate
BBB49_04395	ENOG4105PTM	secreted protein
BBB49_04400	ENOG4108IUK	alpha amylase, catalytic
BBB49_04405	ENOG4108IUM	Glycogen debranching enzyme
BBB49_04415	ENOG4105DR4	Methyltransferase
BBB49_04425	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BBB49_04435	ENOG4105CN5	Metallo-Beta-Lactamase
BBB49_04440	ENOG4105CE1	Ferrous iron transport protein b
BBB49_04450	ENOG4105KST	dependent repressor
BBB49_04485	ENOG4105C8J	)-transporter
BBB49_04490	ENOG4105CHM	Aminotransferase
BBB49_04495	ENOG4105K56	Transcriptional regulator
BBB49_04520	ENOG4105CFM	UPF0317 protein
BBB49_04525	ENOG4105E7W	lamb ycsf family protein
BBB49_04530	ENOG4105P4J	Allophanate hydrolase, subunit 1
BBB49_04545	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BBB49_04560	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BBB49_04570	ENOG4105DTI	Phosphonopyruvate decarboxylase
BBB49_04575	ENOG4107STF	Involved in phosphonate degradation (By similarity)
BBB49_04590	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
BBB49_04600	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
BBB49_04605	ENOG4105BZ8	glutamate synthase
BBB49_04610	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
BBB49_04615	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_04650	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
BBB49_04655	ENOG4105BZ8	glutamate synthase
BBB49_04660	ENOG4107RDB	Major Facilitator
BBB49_04670	ENOG4106N3A	copper homeostasis protein cutc
BBB49_04675	ENOG4108SWU	Histidine kinase
BBB49_04680	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BBB49_04685	ENOG4108RSN	SNARE associated Golgi
BBB49_04690	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BBB49_04700	ENOG4108WCX	response regulator
BBB49_04705	ENOG4105DA5	(ABC) transporter
BBB49_04720	ENOG4105VMP	Transcriptional regulator
BBB49_04745	ENOG4108R66	Conserved Protein
BBB49_04770	ENOG4105C5Q	Transcriptional regulator
BBB49_04780	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BBB49_04785	ENOG4105BZU	Histidine kinase
BBB49_04795	ENOG4105BZG	amino acid carrier protein
BBB49_04800	ENOG41084AG	Acylphosphatase
BBB49_04805	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BBB49_04815	ENOG4105D38	putrescine abc transporter
BBB49_04820	ENOG4105F38	ABC transporter, permease
BBB49_04845	ENOG4105BZ4	penicillin-binding protein
BBB49_04860	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BBB49_04875	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BBB49_04890	ENOG4107QHF	type ii secretion system protein e
BBB49_04895	ENOG4105D7Q	type ii secretion system
BBB49_04945	ENOG4105CFH	Aspartokinase
BBB49_04960	ENOG4108YZA	Nitrogen regulatory protein pii
BBB49_04980	ENOG4105BZ8	glutamate synthase
BBB49_04995	ENOG4105DUM	transcriptional regulator, lysR family
BBB49_05025	ENOG4105C2M	dna polymerase I
BBB49_05035	ENOG4105E4C	Lytic transglycosylase catalytic
BBB49_05065	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BBB49_05070	ENOG4105DDQ	anthranilate synthase
BBB49_05075	ENOG4105CRQ	synthase (Component I)
BBB49_05080	ENOG4107Z5F	Aminotransferase class IV
BBB49_05100	ENOG4105BZU	Histidine kinase
BBB49_05105	ENOG4105BZU	Histidine kinase
BBB49_05110	ENOG4105KAV	tspo and mbr like protein
BBB49_05115	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BBB49_05120	ENOG4105D2X	ABC transporter substrate-binding protein
BBB49_05130	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
BBB49_05150	ENOG4105DZ1	carboxypeptidase
BBB49_05160	ENOG4105F1K	Glutamine amidotransferase
BBB49_05165	ENOG4105DMS	mur ligase
BBB49_05175	ENOG4105CFP	Peptidase U32
BBB49_05180	ENOG4105C98	muts2 protein
BBB49_05185	ENOG4105EWC	Purine nucleoside phosphorylase
BBB49_05190	ENOG4105D5Q	Arginine ornithine antiporter
BBB49_05205	ENOG4105EYH	Exonuclease
BBB49_05210	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BBB49_05215	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BBB49_05235	ENOG4105CJR	Integral membrane protein (MviN
BBB49_05245	ENOG4105CPK	Glycosyl transferase (Group 1
BBB49_05270	ENOG4105C3G	gtp-binding protein
BBB49_05285	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BBB49_05300	ENOG4105CXT	aspartate transcarbamylase
BBB49_05315	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
BBB49_05325	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BBB49_05330	ENOG4107T14	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BBB49_05335	ENOG4105C6N	Formate acetyltransferase
BBB49_05355	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BBB49_05370	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BBB49_05375	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
BBB49_05385	ENOG4108Z4T	Peptidase M50
BBB49_05390	ENOG4105C75	arginyL-tRNA synthetase
BBB49_05395	ENOG4108REF	Sporulation integral membrane protein ytvi
BBB49_05415	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
BBB49_05430	ENOG4105WG9	Conserved Protein
BBB49_05435	ENOG4108VVK	transcriptional Regulator, AsnC
BBB49_05470	ENOG4105CAQ	asparagine synthetase
BBB49_05480	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BBB49_05485	ENOG4105XVJ	Protein of unknown function (DUF327)
BBB49_05500	ENOG4105D7T	ABC transporter
BBB49_05510	ENOG4105BZ1	(ABC) transporter
BBB49_05515	ENOG4105K63	Thioredoxin
BBB49_05520	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BBB49_05525	ENOG4108DWA	Nad synthetase
BBB49_05540	ENOG4105CK2	sodium dicarboxylate symporter
BBB49_05550	ENOG4108HW3	(ABC) transporter
BBB49_05555	ENOG4105DRP	amino acid AbC transporter
BBB49_05560	ENOG4105CDA	abc transporter atp-binding protein
BBB49_05570	ENOG4107R4J	Chloride channel
BBB49_05575	ENOG4105JVQ	RNA Polymerase
BBB49_05585	ENOG4108IJ0	Aspartate ammonia-lyase
BBB49_05595	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BBB49_05610	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BBB49_05615	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BBB49_05620	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BBB49_05625	ENOG4105C12	Phosphoribosylglycinamide synthetase
BBB49_05635	ENOG4105BZU	Histidine kinase
BBB49_05640	ENOG4108115	UPF0145 protein
BBB49_05665	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BBB49_05670	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BBB49_05675	ENOG4105EA8	2-Nitropropane dioxygenase
BBB49_05680	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BBB49_05685	ENOG4105CHR	reductase
BBB49_05690	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BBB49_05705	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BBB49_05710	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BBB49_05715	ENOG4108FRU	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BBB49_05730	ENOG4105C7J	ABC transporter, permease
BBB49_05740	ENOG4105D1H	recombination factor protein RarA
BBB49_05755	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
BBB49_05760	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BBB49_05770	ENOG4105C02	permease
BBB49_05775	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BBB49_05780	ENOG4105VBH	UPF0297 protein
BBB49_05785	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BBB49_05790	ENOG4105VGP	UPF0473 protein
BBB49_05795	ENOG4105I3K	Ferric uptake regulator, Fur family
BBB49_05800	ENOG4105CN5	Metallo-Beta-Lactamase
BBB49_05805	ENOG4105CI3	gtp-binding protein typa
BBB49_05810	ENOG4105HHA	aminodeoxychorismate lyase
BBB49_05815	ENOG4108VQJ	O-methyltransferase
BBB49_05820	ENOG4105CFP	Peptidase U32
BBB49_05830	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBB49_05835	ENOG4105CZX	twitching motility protein
BBB49_05845	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BBB49_05850	ENOG4105FFI	sigma-e processing peptidase spoiiga
BBB49_05855	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBB49_05860	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BBB49_05865	ENOG4105WR5	sporulation protein, YlmC YmxH family
BBB49_05870	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BBB49_05875	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
BBB49_05880	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_05885	ENOG4105BZU	Histidine kinase
BBB49_05890	ENOG4105CVA	phosphate
BBB49_05895	ENOG4105C8U	phosphate abc transporter
BBB49_05900	ENOG4105E2Z	phosphate ABC transporter (Permease
BBB49_05905	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BBB49_05910	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BBB49_05925	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BBB49_05930	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BBB49_05935	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
BBB49_05945	ENOG4105HDK	L-asparaginase
BBB49_05950	ENOG4105C7N	Xanthine uracil vitamin C permease
BBB49_05955	ENOG4105DSJ	YicC domain protein
BBB49_05970	ENOG410880J	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BBB49_05975	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BBB49_05980	ENOG4105C25	Primosomal protein n'
BBB49_05990	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BBB49_05995	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BBB49_06000	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BBB49_06005	ENOG4108ZF3	Phosphatase
BBB49_06015	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BBB49_06020	ENOG4105DJV	ribulose-phosphate 3-epimerase
BBB49_06030	ENOG4105VB9	50S ribosomal protein l28
BBB49_06040	ENOG4105DP4	dak2 domain fusion protein ylov
BBB49_06045	ENOG4105CQ4	Transcriptional regulator
BBB49_06050	ENOG4105CB5	ATP-dependent DNA helicase recG
BBB49_06055	ENOG4106H78	methyltransferase
BBB49_06060	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BBB49_06075	ENOG4105CDE	UPF0348 protein
BBB49_06080	ENOG4108IJ2	phosphate acetyltransferase
BBB49_06085	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BBB49_06095	ENOG41067VY	50S ribosomal protein L32
BBB49_06100	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BBB49_06105	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BBB49_06110	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BBB49_06125	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BBB49_06130	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
BBB49_06140	ENOG4105K5M	30s ribosomal protein S16
BBB49_06150	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BBB49_06155	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BBB49_06160	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BBB49_06165	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BBB49_06170	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BBB49_06180	ENOG4105C0P	Mg chelatase subunit ChlI
BBB49_06185	ENOG4105C79	DNA protecting protein DprA
BBB49_06190	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BBB49_06195	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
BBB49_06200	ENOG4105CE9	30S ribosomal protein S2
BBB49_06210	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BBB49_06220	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BBB49_06225	ENOG4105KNE	Phosphatidate cytidylyltransferase
BBB49_06260	ENOG4105CHV	Transcription elongation factor NusA
BBB49_06265	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
BBB49_06275	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BBB49_06280	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BBB49_06295	ENOG4105DTN	riboflavin biosynthesis protein ribF
BBB49_06300	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BBB49_06305	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BBB49_06310	ENOG4105C1V	Peptidase, M16
BBB49_06330	ENOG4108UW5	maltose o-acetyltransferase
BBB49_06335	ENOG4105CID	antiterminator
BBB49_06340	ENOG4105C5Y	PTS System
BBB49_06350	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
BBB49_06360	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BBB49_06365	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BBB49_06370	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BBB49_06375	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BBB49_06380	ENOG4105MCT	stage V sporulation protein S
BBB49_06410	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BBB49_06415	ENOG4108R6K	riboflavin synthase, subunit alpha
BBB49_06420	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BBB49_06425	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BBB49_06435	ENOG4105KY8	Rubrerythrin
BBB49_06465	ENOG4105HEE	Binding Domain protein
BBB49_06480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_06485	ENOG4105F3H	Histidine kinase
BBB49_06490	ENOG4108VW9	Membrane
BBB49_06500	ENOG4108YZA	Nitrogen regulatory protein pii
BBB49_06505	ENOG4107QKW	extracellular solute-binding protein family 1
BBB49_06510	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BBB49_06515	ENOG4105F38	ABC transporter, permease
BBB49_06520	ENOG4105D38	putrescine abc transporter
BBB49_06530	ENOG4105C26	Dehydrogenase
BBB49_06540	ENOG41061ZR	Transcriptional regulator
BBB49_06550	ENOG4107S8T	NAD-dependent 4-hydroxybutyrate dehydrogenase
BBB49_06565	ENOG4107U9B	transcriptional regulator
BBB49_06570	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BBB49_06585	ENOG4107XGZ	Hydrolase
BBB49_06605	ENOG4105UQX	Mate efflux family protein
BBB49_06615	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BBB49_06625	ENOG4107RWR	Sodium hydrogen exchanger
BBB49_06645	ENOG4105BZU	Histidine kinase
BBB49_06665	ENOG4105CHR	reductase
BBB49_06670	ENOG4105BZU	Histidine kinase
BBB49_06675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_06680	ENOG4108J6I	peptidase, M16
BBB49_06705	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
BBB49_06715	ENOG4105UQX	Mate efflux family protein
BBB49_06735	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BBB49_06740	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
BBB49_06745	ENOG4105CR5	Class II aldolase adducin family protein
BBB49_06750	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
BBB49_06755	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BBB49_06760	ENOG4105W7A	Protein of unknown function (DUF503)
BBB49_06770	ENOG4105DU1	integral membrane protein, terc
BBB49_06810	ENOG4108IUM	Glycogen debranching enzyme
BBB49_06815	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BBB49_06820	ENOG4105CHM	Aminotransferase
BBB49_06825	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BBB49_06830	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BBB49_06840	ENOG4108JQ7	(ABC) transporter
BBB49_06845	ENOG4108J59	Extracellular solute-binding protein, family 5
BBB49_06850	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BBB49_06855	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
BBB49_06865	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BBB49_06870	ENOG4107RRN	ABC transporter substrate-binding protein
BBB49_06875	ENOG4105C3U	ABC transporter
BBB49_06880	ENOG4108JQ7	(ABC) transporter
BBB49_06890	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BBB49_06900	ENOG4105DXX	methyltransferase
BBB49_06905	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BBB49_06910	ENOG4105FKZ	Methyl-accepting chemotaxis
BBB49_06920	ENOG4107TUM	Amidinotransferase
BBB49_06925	ENOG4108JCI	Transcriptional regulator
BBB49_06945	ENOG4108JPW	Aminotransferase
BBB49_06955	ENOG4105C8Y	Acetylornithine aminotransferase
BBB49_06960	ENOG4107YTP	response regulator receiver protein
BBB49_06995	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BBB49_07005	ENOG4107ZYR	domain protein
BBB49_07010	ENOG4108RWN	rrna methyltransferase
BBB49_07015	ENOG4105CBX	hi0933 family
BBB49_07035	ENOG4107BJW	polysaccharide deacetylase
BBB49_07050	ENOG4105BZ1	(ABC) transporter
BBB49_07060	ENOG4105VUC	UPF0237 protein
BBB49_07065	ENOG4105CAG	UPF0210 protein
BBB49_07095	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BBB49_07100	ENOG4105CGK	Exodeoxyribonuclease III
BBB49_07120	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BBB49_07145	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
BBB49_07165	ENOG4105EQD	regulatoR
BBB49_07170	ENOG4105C2F	Histidine kinase
BBB49_07180	ENOG4105D56	permease protein
BBB49_07185	ENOG4105EG2	ABC transporter, permease
BBB49_07200	ENOG4108IUM	Glycogen debranching enzyme
BBB49_07220	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BBB49_07225	ENOG4105EUJ	GTP cyclohydrolase i
BBB49_07230	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BBB49_07235	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BBB49_07245	ENOG41083AI	transcriptional regulator), MarR family
BBB49_07250	ENOG4105BZ1	(ABC) transporter
BBB49_07255	ENOG4105BZ1	(ABC) transporter
BBB49_07280	ENOG4105DZ1	carboxypeptidase
BBB49_07290	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BBB49_07295	ENOG4105KBJ	sporulation protein ytfj
BBB49_07305	ENOG4105DZ1	carboxypeptidase
BBB49_07325	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
BBB49_07330	ENOG4105DBV	ornithine carbamoyltransferase
BBB49_07335	ENOG4108W76	histidinol phosphate phosphatase hisj family
BBB49_07345	ENOG4107X8C	Efflux transporter RND family MFP subunit
BBB49_07350	ENOG4105CW7	secretion protein, HlyD family
BBB49_07355	ENOG4105BZ1	(ABC) transporter
BBB49_07385	ENOG4105C98	muts2 protein
BBB49_07400	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BBB49_07410	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
BBB49_07420	ENOG4105QUH	Domain of unknown function (DUF2088)
BBB49_07425	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BBB49_07430	ENOG4108I5D	sulfate abc transporter
BBB49_07435	ENOG4105ECW	sulfate abc transporter
BBB49_07440	ENOG4108IJ6	ABC transporter
BBB49_07450	ENOG4105WCA	Ferredoxin
BBB49_07455	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BBB49_07460	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
BBB49_07485	ENOG4108Z86	Glutamine amidotransferase
BBB49_07495	ENOG4108RCM	Nitroreductase
BBB49_07505	ENOG4105BZJ	Electron transfer flavoprotein
BBB49_07510	ENOG4105C10	Electron transfer flavoprotein
BBB49_07520	ENOG4105CQB	FAD linked oxidase domain protein
BBB49_07525	ENOG4105C1G	acyl-Coa dehydrogenase
BBB49_07580	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
BBB49_07585	ENOG4105DZC	cytosine deaminase
BBB49_07625	ENOG4105C4R	Atp-dependent dna helicase
BBB49_07655	ENOG4105CDU	Replicative dna helicase
BBB49_07675	ENOG4107R3N	Filamentation induced by cAMP protein fic
BBB49_07680	ENOG4105C4Y	ABC transporter
BBB49_07685	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BBB49_07690	ENOG4107RCV	ABC transporter, permease
BBB49_07700	ENOG4107VQW	regulatoR
BBB49_07715	ENOG4105D5G	Transposase
BBB49_07720	ENOG4105M6F	mutator MutT protein
BBB49_07725	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BBB49_07740	ENOG4105CH2	amidohydrolase
BBB49_07745	ENOG4105CGH	5'-nucleotidase
BBB49_07760	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
BBB49_07765	ENOG4105CIZ	coA-substrate-specific enzyme activase
BBB49_07805	ENOG4105CVJ	phosphoglycerate mutase
BBB49_07810	ENOG4105E0M	Sulfatase
BBB49_07830	ENOG4108X4Q	Hydrolase
BBB49_07840	ENOG4105BZU	Histidine kinase
BBB49_07845	ENOG4105CPC	Aldo Keto reductase
BBB49_07850	ENOG4107SC7	Inner membrane transporter yjeM
BBB49_07860	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
BBB49_07865	ENOG4105DVE	abc transporter atp-binding protein
BBB49_07885	ENOG4105VEQ	Cold shock protein
BBB49_07900	ENOG4105D64	Mechanosensitive ion channel
BBB49_07915	ENOG4105E5D	amino acid
BBB49_07940	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BBB49_07950	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BBB49_07955	ENOG4105DIW	FeS assembly protein SUFB
BBB49_07990	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BBB49_08005	ENOG4105DHS	permease protein
BBB49_08010	ENOG4105CM4	permease protein
BBB49_08015	ENOG4108IPW	abc transporter atp-binding protein
BBB49_08025	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BBB49_08065	ENOG4107SGM	protein serine threonine phosphatase
BBB49_08070	ENOG4105DHI	Methyltransferase
BBB49_08075	ENOG4105EAM	Na Pi-cotransporter
BBB49_08080	ENOG4108ZMI	UPF0477 protein
BBB49_08105	ENOG4105C1A	potassium transporter peripheral membrane
BBB49_08110	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
BBB49_08115	ENOG4105FE9	pseudouridine synthase
BBB49_08125	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BBB49_08135	ENOG4107RVG	penicillin-binding protein
BBB49_08140	ENOG4105BZU	Histidine kinase
BBB49_08165	ENOG4108VJ1	Transcriptional regulator (CarD family
BBB49_08170	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BBB49_08185	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BBB49_08190	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BBB49_08210	ENOG4105DER	m42 family
BBB49_08225	ENOG4105EW4	(LipO)protein
BBB49_08235	ENOG4105CKI	cobalamin synthesis protein
BBB49_08245	ENOG4108PJD	permease
BBB49_08260	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BBB49_08340	ENOG4108HW3	(ABC) transporter
BBB49_08345	ENOG4105E5Q	amino acid AbC transporter
BBB49_08360	ENOG4105ETU	transcriptional activator (TenA
BBB49_08370	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
BBB49_08405	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
BBB49_08410	ENOG4107QQ0	gntp family
BBB49_08415	ENOG4105BZW	Glycerate kinase
BBB49_08425	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
BBB49_08430	ENOG4105CBX	hi0933 family
BBB49_08440	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BBB49_08455	ENOG4105CKI	cobalamin synthesis protein
BBB49_08475	ENOG4108Z66	YbaK ebsC protein
BBB49_08480	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBB49_08495	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BBB49_08500	ENOG4105CXI	aluminum resistance protein
BBB49_08510	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BBB49_08515	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BBB49_08520	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BBB49_08540	ENOG4105C7N	Xanthine uracil vitamin C permease
BBB49_08555	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BBB49_08560	ENOG4105KWG	Pfam:DUF1696
BBB49_08570	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BBB49_08585	ENOG4107RBB	ABC transporter, permease
BBB49_08590	ENOG4105C19	ABC transporter
BBB49_08605	ENOG4105BZU	Histidine kinase
BBB49_08615	ENOG4108IFG	nitrite reductase, (NAD(P)H)
BBB49_08630	ENOG41069ER	domain protein
BBB49_08635	ENOG4108UH6	UPF0754 membrane protein
BBB49_08650	ENOG4105EAM	Na Pi-cotransporter
BBB49_08655	ENOG4105KT7	mgtC SapB transporter
BBB49_08670	ENOG4105C5H	ABC transporter
BBB49_08700	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BBB49_08705	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BBB49_08710	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BBB49_08715	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BBB49_08720	ENOG4105DDQ	anthranilate synthase
BBB49_08725	ENOG4105CRQ	synthase (Component I)
BBB49_08730	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
BBB49_08735	ENOG4105C1J	atp-dependent rna helicase
BBB49_08795	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
BBB49_08825	ENOG4105E98	transcriptional regulator DeoR family
BBB49_08830	ENOG4108X4Q	Hydrolase
BBB49_08835	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BBB49_08850	ENOG4105D6J	arsenicaL-resistance protein
BBB49_08870	ENOG4105YVS	arsR family transcriptional regulator
BBB49_08880	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BBB49_08890	ENOG4107YTP	response regulator receiver protein
BBB49_08900	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BBB49_08910	ENOG4108HCJ	Hydrolase
BBB49_08930	ENOG4105CN5	Metallo-Beta-Lactamase
BBB49_08935	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
BBB49_08940	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
BBB49_08950	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BBB49_08965	ENOG4108YZ4	nudix hydrolase
BBB49_08970	ENOG410807C	QueT transporter
BBB49_08990	ENOG4105C3S	Mate efflux family protein
BBB49_08995	ENOG4105KNA	-acetyltransferase
BBB49_09005	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BBB49_09010	ENOG4105KT7	mgtC SapB transporter
BBB49_09030	ENOG4105F6S	Spore photoproduct lyase
BBB49_09035	ENOG4108UYN	gCN5-related N-acetyltransferase
BBB49_09085	ENOG4105K64	Glycosyl transferase, family 2
BBB49_09125	ENOG4108428	Inherit from COG: -acetyltransferase
BBB49_09135	ENOG4105WEF	catalase
BBB49_09165	ENOG4105DVT	helicase
BBB49_09205	ENOG4105CDU	Replicative dna helicase
BBB49_09260	ENOG4105BZU	Histidine kinase
BBB49_09265	ENOG4105EC8	Methyl-accepting chemotaxis
BBB49_09285	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
BBB49_09340	ENOG4108V4B	ThiJ pfpI
BBB49_09350	ENOG4105KVH	Transcriptional regulator
BBB49_09380	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BBB49_09430	ENOG4108Z0Z	intracellular protease Pfpi family
BBB49_09435	ENOG4105C5H	ABC transporter
BBB49_09440	ENOG4105VUF	Transcriptional regulator
BBB49_09450	ENOG4108ZQX	ybak prolyl-trna synthetase
BBB49_09455	ENOG4108Z0Z	intracellular protease Pfpi family
BBB49_09525	ENOG4105DA5	(ABC) transporter
BBB49_09545	ENOG4107QJQ	Mate efflux family protein
BBB49_09550	ENOG4105C4B	ABC transporter, permease
BBB49_09555	ENOG41083J0	(ABC) transporter
BBB49_09585	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
BBB49_09595	ENOG4105C7W	Xanthine dehydrogenase
BBB49_09625	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
BBB49_09630	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
BBB49_09635	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
BBB49_09645	ENOG4108JCI	Transcriptional regulator
BBB49_09655	ENOG4107RN3	metallophosphoesterase
BBB49_09665	ENOG4107QHI	-hydrogenase
BBB49_09670	ENOG4107QIZ	NADH dehydrogenase
BBB49_09680	ENOG4105I1K	ABC transporter
BBB49_09690	ENOG4107YY3	extracellular solute-binding protein family 1
BBB49_09695	ENOG4105CG3	alpha amylase, catalytic region
BBB49_09700	ENOG4105ETE	Transcriptional regulator (LacI family
BBB49_09725	ENOG4105CQB	FAD linked oxidase domain protein
BBB49_09730	ENOG4108UMI	ABC transporter, permease
BBB49_09735	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BBB49_09740	ENOG4105D01	(LipO)protein
BBB49_09745	ENOG4105CHM	Aminotransferase
BBB49_09750	ENOG4105C28	cystathionine
BBB49_09760	ENOG4105UPD	Calcium Proton
BBB49_09765	ENOG4106F1P	AAA ATPase, central domain protein
BBB49_09770	ENOG4105CVJ	phosphoglycerate mutase
BBB49_09810	ENOG4105CHM	Aminotransferase
BBB49_09815	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBB49_09825	ENOG4107QSE	Dipeptidase
BBB49_09850	ENOG4105DQ6	Transposase
BBB49_09855	ENOG4107R88	Chemotaxis protein (CheV)
BBB49_09865	ENOG4105BZU	Histidine kinase
BBB49_09880	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BBB49_09885	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBB49_09895	ENOG4105D9U	N-acetyltransferase
BBB49_09915	ENOG4107IFA	Lipase (EC 3.1.1.3)
BBB49_09920	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BBB49_10005	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BBB49_10030	ENOG4105DM4	PTS System
BBB49_10035	ENOG4105DE4	1-phosphofructokinase
BBB49_10040	ENOG4105E98	transcriptional regulator DeoR family
BBB49_10055	ENOG4105CT4	transporter
BBB49_10070	ENOG4105F5H	Glycosyl Hydrolase Family 88
BBB49_10080	ENOG4105CHR	reductase
BBB49_10085	ENOG4105CTX	dehydratase
BBB49_10090	ENOG4107QZW	Altronate oxidoreductase
BBB49_10095	ENOG4105D7K	pfkb domain protein
BBB49_10100	ENOG4108UHU	Aldolase
BBB49_10105	ENOG4105D2H	Uronic isomerase
BBB49_10110	ENOG4107KJX	Transcriptional regulator
BBB49_10135	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BBB49_10140	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BBB49_10145	ENOG4105DRP	amino acid AbC transporter
BBB49_10150	ENOG4105EAD	ABC transporter
BBB49_10155	ENOG4107RP9	extracellular solute-binding protein, family 3
BBB49_10170	ENOG4105C1J	atp-dependent rna helicase
BBB49_10180	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BBB49_10190	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BBB49_10200	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BBB49_10215	ENOG4105XXY	Thioredoxin
BBB49_10220	ENOG410667J	hydrolase
BBB49_10225	ENOG410631K	Membrane
BBB49_10255	ENOG4105C7K	acetolactate synthase
BBB49_10260	ENOG4105M71	acetolactate synthase 1 regulatory subunit
BBB49_10265	ENOG410901E	Membrane
BBB49_10270	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BBB49_10275	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BBB49_10280	ENOG41086VR	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BBB49_10285	ENOG4105C5S	asparaginyl-tRNA synthetase
BBB49_10295	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
BBB49_10300	ENOG4107V2S	Transcriptional regulator
BBB49_10320	ENOG4107Y70	Heat shock protein
BBB49_10340	ENOG4107R4J	Chloride channel
BBB49_10355	ENOG4105BZU	Histidine kinase
BBB49_10400	ENOG4107QIV	Cytochrome c biogenesis protein
BBB49_10405	ENOG4105KVH	Transcriptional regulator
BBB49_10415	ENOG4107QN2	dihydrolipoyl dehydrogenase
BBB49_10420	ENOG4105K63	Thioredoxin
BBB49_10425	ENOG4105C3M	thioredoxin reductase
BBB49_10435	ENOG4105WEF	catalase
BBB49_10440	ENOG4108YZ4	nudix hydrolase
BBB49_10450	ENOG4108Z29	Flavodoxin
BBB49_10460	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBB49_10470	ENOG4105CK7	Sodium proline symporter
BBB49_10480	ENOG4105EC8	Methyl-accepting chemotaxis
BBB49_10495	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBB49_10510	ENOG4108IV0	ABC, transporter
BBB49_10515	ENOG4105C0Z	ABC transporter
BBB49_10520	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BBB49_10525	ENOG4105C32	Amino acid ABC transporter (Permease)
BBB49_10535	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
BBB49_10540	ENOG4107QQR	Sporulation
BBB49_10595	ENOG4107QQR	Sporulation
BBB49_10600	ENOG4105S1Z	Stage IV sporulation protein B
BBB49_10605	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BBB49_10610	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
BBB49_10615	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BBB49_10620	ENOG4105DX0	Hemolysin A
BBB49_10625	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BBB49_10630	ENOG4105CTB	Polyprenyl synthetase
BBB49_10635	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BBB49_10640	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BBB49_10650	ENOG4105M7K	Involved in the transcription termination process (By similarity)
BBB49_10655	ENOG4108ZSR	alkaline shock protein
BBB49_10680	ENOG4105KQ4	Stage iii sporulation protein ad
BBB49_10695	ENOG4105CD2	stage iii sporulation protein aa
BBB49_10765	ENOG4105F23	Fibronectin-binding protein
BBB49_10770	ENOG4105QEK	Transcriptional regulator
BBB49_10775	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BBB49_10785	ENOG4105C34	Pseudouridine synthase
BBB49_10805	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BBB49_10810	ENOG4105DFA	alanine racemase domain protein
BBB49_10820	ENOG4105K67	small basic protein
BBB49_10840	ENOG4105CNI	cell division protein FtsW
BBB49_10845	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BBB49_10850	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
BBB49_10860	ENOG4105CJN	penicillin-binding protein
BBB49_10865	ENOG4105CJN	penicillin-binding protein
BBB49_10875	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BBB49_10880	ENOG4108V6E	Cell division protein mraZ
BBB49_10905	ENOG410890F	Dynamin family
BBB49_10935	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BBB49_10945	ENOG410828M	hemerythrin-like, metal-binding protein
BBB49_10950	ENOG4105D22	carbon starvation protein
BBB49_10965	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
BBB49_10975	ENOG4105C26	Dehydrogenase
BBB49_10980	ENOG4105CFP	Peptidase U32
BBB49_11000	ENOG4107QJQ	Mate efflux family protein
BBB49_11020	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
BBB49_11045	ENOG4105VFE	sira family
BBB49_11050	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BBB49_11055	ENOG4105DWK	Membrane
BBB49_11085	ENOG4105C02	permease
BBB49_11100	ENOG4105FE9	pseudouridine synthase
BBB49_11130	ENOG4105C5H	ABC transporter
BBB49_11140	ENOG4105I08	Pseudouridine synthase
BBB49_11145	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_11160	ENOG4105C7B	Threonine dehydratase
BBB49_11170	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
BBB49_11175	ENOG4105C02	permease
BBB49_11180	ENOG4105DBI	uridine monophosphokinase
BBB49_11190	ENOG4105EPR	degv family
BBB49_11220	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BBB49_11225	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BBB49_11230	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
BBB49_11235	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
BBB49_11245	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BBB49_11250	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_11270	ENOG4108KGH	TRANSCRIPTIONal
BBB49_11280	ENOG4105CAQ	asparagine synthetase
BBB49_11285	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
BBB49_11290	ENOG4107YJ4	chain length determinant protein
BBB49_11300	ENOG4105BZ1	(ABC) transporter
BBB49_11340	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BBB49_11345	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BBB49_11350	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
BBB49_11375	ENOG4107RA4	Glycosyl transferase (Group 1
BBB49_11385	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
BBB49_11390	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BBB49_11395	ENOG4105HTX	biosynthesis protein
BBB49_11405	ENOG4105D3Q	Sugar transferase
BBB49_11415	ENOG4108UQV	Membrane
BBB49_11420	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BBB49_11425	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BBB49_11440	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
BBB49_11450	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BBB49_11470	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
BBB49_11480	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BBB49_11485	ENOG410810Y	Sulfite reductase
BBB49_11490	ENOG4107SHJ	sulfite reductase subunit b
BBB49_11495	ENOG4105D5B	Sulfite reductase, subunit A
BBB49_11510	ENOG4105BZU	Histidine kinase
BBB49_11515	ENOG4105C9M	aspartyl-trna synthetase
BBB49_11520	ENOG4105CUT	histidyl-tRNA synthetase
BBB49_11525	ENOG4105D4P	Coproporphyrinogen iii oxidase
BBB49_11530	ENOG4105C5X	domain protein
BBB49_11535	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BBB49_11540	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BBB49_11545	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BBB49_11550	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BBB49_11555	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BBB49_11560	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BBB49_11575	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BBB49_11580	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BBB49_11585	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BBB49_11590	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BBB49_11670	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
BBB49_11680	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBB49_11690	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BBB49_11740	ENOG4105ZX1	Transposase C
BBB49_11745	ENOG4108KU9	integrase family
BBB49_11750	ENOG4108KU9	integrase family
BBB49_11755	ENOG4108FPN	Integrase
BBB49_11870	ENOG4108M14	stage v sporulation protein t
BBB49_11900	ENOG4105VTR	Integrase
BBB49_11925	ENOG4108UHU	Aldolase
BBB49_11945	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
BBB49_11955	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
BBB49_11960	ENOG4108IUK	alpha amylase, catalytic
BBB49_11965	ENOG4105EG2	ABC transporter, permease
BBB49_11970	ENOG4105D56	permease protein
BBB49_11975	ENOG4107FKK	extracellular solute-binding protein family 1
BBB49_11980	ENOG4106HBX	Transcriptional Regulator AraC Family
BBB49_11985	ENOG4107RBB	ABC transporter, permease
BBB49_11990	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BBB49_12005	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_12015	ENOG4108UVJ	appr-1-p processing domain protein
BBB49_12020	ENOG4105KY8	Rubrerythrin
BBB49_12030	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BBB49_12050	ENOG4105DB7	PHP domain protein
BBB49_12055	ENOG4105DFM	M18 family aminopeptidase
BBB49_12060	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BBB49_12100	ENOG4105C3R	Methionine synthase
BBB49_12110	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BBB49_12185	ENOG4105CS2	ec 3.2.1.21
BBB49_12190	ENOG4105C5Y	PTS System
BBB49_12195	ENOG4105CID	antiterminator
BBB49_12205	ENOG4105EI2	Pseudouridine synthase
BBB49_12210	ENOG4105CH2	amidohydrolase
BBB49_12215	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BBB49_12235	ENOG4105DAP	Nicotinate phosphoribosyltransferase
BBB49_12250	ENOG4105G5W	regulator Fur family
BBB49_12280	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BBB49_12285	ENOG4108IUQ	atp-dependent protease
BBB49_12290	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BBB49_12300	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BBB49_12315	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BBB49_12320	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
BBB49_12325	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BBB49_12330	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BBB49_12335	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BBB49_12340	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BBB49_12345	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BBB49_12350	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BBB49_12355	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BBB49_12385	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BBB49_12390	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BBB49_12410	ENOG41090I5	UPF0735 ACT domain-containing protein
BBB49_12415	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BBB49_12420	ENOG4107QID	Threonine synthase
BBB49_12440	ENOG4107RUE	extracellular solute-binding protein family 1
BBB49_12445	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
BBB49_12455	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BBB49_12460	ENOG4105D52	delta-aminolevulinic acid dehydratase
BBB49_12465	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BBB49_12480	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BBB49_12485	ENOG410810Y	Sulfite reductase
BBB49_12490	ENOG4105F4P	)-transporter
BBB49_12500	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BBB49_12505	ENOG410696E	Membrane
BBB49_12510	ENOG4105CVG	Homoserine O-transsuccinylase
BBB49_12515	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
BBB49_12520	ENOG4105CPN	adenine deaminase
BBB49_12530	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BBB49_12535	ENOG410667J	hydrolase
BBB49_12555	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BBB49_12560	ENOG4107QZB	decarboxylase
BBB49_12575	ENOG4105E4R	Precorrin-3B C17-methyltransferase
BBB49_12580	ENOG4108P62	biosynthesis protein (CbiG)
BBB49_12585	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
BBB49_12595	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
BBB49_12600	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
BBB49_12605	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
BBB49_12610	ENOG41081F0	Precorrin-8x methylmutase
BBB49_12615	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BBB49_12620	ENOG4107PPM	cobalt chelatase
BBB49_12625	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
BBB49_12635	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_12650	ENOG4105D9N	nucleoside
BBB49_12655	ENOG4105DRR	Transcriptional regulator, GntR family
BBB49_12670	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
BBB49_12675	ENOG4108IUS	Transketolase
BBB49_12680	ENOG4108HHA	Transketolase
BBB49_12695	ENOG4105KG3	cytidine deaminase
BBB49_12700	ENOG4105D9N	nucleoside
BBB49_12705	ENOG4108I5U	Uridine phosphorylase
BBB49_12730	ENOG4108IUS	Transketolase
BBB49_12735	ENOG4108HHA	Transketolase
BBB49_12745	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
BBB49_12760	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
BBB49_12775	ENOG4105E98	transcriptional regulator DeoR family
BBB49_12780	ENOG4105C8J	)-transporter
BBB49_12790	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
BBB49_12830	ENOG4108IY8	ABC, transporter
BBB49_12835	ENOG4106FTQ	Taurine ABC transporter, periplasmic
BBB49_12840	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
BBB49_12845	ENOG4105DQ6	Transposase
BBB49_12850	ENOG4107YHD	transcriptional regulator
BBB49_12865	ENOG4105BZU	Histidine kinase
BBB49_12870	ENOG4108UW5	maltose o-acetyltransferase
BBB49_12875	ENOG4105CG3	alpha amylase, catalytic region
BBB49_12880	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BBB49_12895	ENOG4105CAH	Chromate
BBB49_12930	ENOG4108R6W	Transcriptional regulator, ARAC family
BBB49_12940	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
BBB49_12945	ENOG4105EQD	regulatoR
BBB49_12950	ENOG4105C2F	Histidine kinase
BBB49_12955	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_12960	ENOG4105C4C	beta-galactosidase
BBB49_12980	ENOG4105CQ4	Transcriptional regulator
BBB49_12995	ENOG4105CYW	agmatinase
BBB49_13015	ENOG4105CXN	decarboxylase
BBB49_13030	ENOG4105G6Z	alkaline phosphatase
BBB49_13040	ENOG4105DKQ	ROK family
BBB49_13075	ENOG4105DRS	transport system, permease
BBB49_13080	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BBB49_13095	ENOG4108R6W	Transcriptional regulator, ARAC family
BBB49_13100	ENOG4107RK0	Sucrose phosphorylase
BBB49_13105	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BBB49_13110	ENOG4105CMR	udp-glucose 4-epimerase
BBB49_13115	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
BBB49_13120	ENOG4105ETE	Transcriptional regulator (LacI family
BBB49_13140	ENOG4108S8M	degv family
BBB49_13145	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
BBB49_13155	ENOG4105C2F	Histidine kinase
BBB49_13160	ENOG4105EQD	regulatoR
BBB49_13170	ENOG4108HWW	ABC transporter
BBB49_13180	ENOG4105DFW	ABC transporter
BBB49_13195	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BBB49_13215	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
BBB49_13220	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
BBB49_13225	ENOG410667J	hydrolase
BBB49_13240	ENOG4105DB7	PHP domain protein
BBB49_13245	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BBB49_13255	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BBB49_13260	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
BBB49_13285	ENOG4105EQ0	Major Facilitator superfamily
BBB49_13290	ENOG4108NGU	Transcriptional regulator
BBB49_13305	ENOG4105C5H	ABC transporter
BBB49_13325	ENOG4107ZYR	domain protein
BBB49_13330	ENOG4105CZN	Potassium uptake protein
BBB49_13340	ENOG4108JJB	ABC transporter
BBB49_13355	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
BBB49_13365	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
BBB49_13370	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
BBB49_13375	ENOG4105CQM	Urea amidohydrolase subunit alpha
BBB49_13380	ENOG4108F09	Urease subunit gamma beta
BBB49_13385	ENOG4108YZ9	Urea amidohydrolase subunit gamma
BBB49_13400	ENOG4107XCH	Cyclase family
BBB49_13405	ENOG4105C26	Dehydrogenase
BBB49_13410	ENOG4105C0A	alcohol dehydrogenase
BBB49_13420	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BBB49_13425	ENOG4108YZA	Nitrogen regulatory protein pii
BBB49_13430	ENOG4108YZA	Nitrogen regulatory protein pii
BBB49_13435	ENOG4107YHD	transcriptional regulator
BBB49_13445	ENOG4105CYW	agmatinase
BBB49_13455	ENOG4108YZA	Nitrogen regulatory protein pii
BBB49_13460	ENOG4108IV0	ABC, transporter
BBB49_13465	ENOG4105C0Z	ABC transporter
BBB49_13475	ENOG4105C32	Amino acid ABC transporter (Permease)
BBB49_13485	ENOG4105EQD	regulatoR
BBB49_13490	ENOG4105BZU	Histidine kinase
BBB49_13500	ENOG4105EJQ	L-serine dehydratase
BBB49_13520	ENOG4105C22	threonyL-tRNA synthetase
BBB49_13525	ENOG4108QG2	Membrane
BBB49_13535	ENOG4105CDH	Citrulline--aspartate ligase
BBB49_13540	ENOG4105CH7	arginosuccinase
BBB49_13545	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BBB49_13555	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BBB49_13560	ENOG4105CAS	nag kinase
BBB49_13565	ENOG4105C8Y	Acetylornithine aminotransferase
BBB49_13570	ENOG4105DBV	ornithine carbamoyltransferase
BBB49_13575	ENOG4105VKD	bioY protein
BBB49_13605	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
BBB49_13615	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
BBB49_13620	ENOG4108TZY	GntR Family Transcriptional Regulator
BBB49_13625	ENOG4105DG6	mannose-6-phosphate isomerase
BBB49_13630	ENOG4105CS2	ec 3.2.1.21
BBB49_13635	ENOG4108K2F	hydrolase Family 5
BBB49_13655	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_13660	ENOG4105CKB	glycosidase
BBB49_13665	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BBB49_13695	ENOG4107VQW	regulatoR
BBB49_13700	ENOG4105C2F	Histidine kinase
BBB49_13705	ENOG4105D5G	Transposase
BBB49_13725	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
BBB49_13735	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BBB49_13745	ENOG4105I82	acetyl xylan esterase
BBB49_13750	ENOG4107EFR	Flavocytochrome c
BBB49_13755	ENOG4107SCR	N-acetylneuraminate lyase
BBB49_13760	ENOG4108JQ7	(ABC) transporter
BBB49_13770	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BBB49_13785	ENOG4105DQ6	Transposase
BBB49_13790	ENOG4105QEK	Transcriptional regulator
BBB49_13800	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
BBB49_13810	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
BBB49_13815	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BBB49_13825	ENOG4105E2X	shikimate dehydrogenase
BBB49_13830	ENOG4105EMV	Major Facilitator
BBB49_13835	ENOG4105FTV	AraC Family Transcriptional Regulator
BBB49_13845	ENOG4105C5Q	Transcriptional regulator
BBB49_13855	ENOG4105E2X	shikimate dehydrogenase
BBB49_13860	ENOG4105CQC	Prephenate dehydratase
BBB49_13865	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BBB49_13870	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BBB49_13875	ENOG4105D49	3-dehydroquinate synthase
BBB49_13880	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
BBB49_13900	ENOG4105C8T	Leucyl-tRNA synthetase
BBB49_13915	ENOG4105CJ1	ABC, transporter
BBB49_13920	ENOG4107S9R	deoxycytidine triphosphate deaminase
BBB49_13965	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_13985	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BBB49_13995	ENOG4105BZU	Histidine kinase
BBB49_14000	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BBB49_14010	ENOG4105EKQ	RNA-directed DNA polymerase
BBB49_14015	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BBB49_14020	ENOG4105BZU	Histidine kinase
BBB49_14025	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_14035	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BBB49_14040	ENOG4108TU7	Inherit from COG: (ABC) transporter
BBB49_14045	ENOG4105CJ1	ABC, transporter
BBB49_14050	ENOG4105KY8	Rubrerythrin
BBB49_14065	ENOG4105D5G	Transposase
BBB49_14070	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_14075	ENOG410667J	hydrolase
BBB49_14080	ENOG4105CS2	ec 3.2.1.21
BBB49_14085	ENOG4105F8D	glycoside hydrolase family 4
BBB49_14090	ENOG4106MCE	EamA-like transporter family
BBB49_14095	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BBB49_14100	ENOG4107SCR	N-acetylneuraminate lyase
BBB49_14105	ENOG4107RJ1	sodium solute
BBB49_14125	ENOG4107T9C	Alpha amylase catalytic region
BBB49_14160	ENOG4108KN0	Choline kinase
BBB49_14180	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BBB49_14185	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BBB49_14190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BBB49_14260	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BBB49_14270	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_14280	ENOG4105DEF	Extracellular solute-binding protein, family 5
BBB49_14285	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BBB49_14290	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BBB49_14295	ENOG4105C3U	ABC transporter
BBB49_14300	ENOG4108JQ7	(ABC) transporter
BBB49_14315	ENOG4105CMR	udp-glucose 4-epimerase
BBB49_14325	ENOG4108SEH	involved in lipopolysaccharide biosynthesis
BBB49_14345	ENOG4105K64	Glycosyl transferase, family 2
BBB49_14360	ENOG4105K64	Glycosyl transferase, family 2
BBB49_14375	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
BBB49_14380	ENOG4105D3Q	Sugar transferase
BBB49_14390	ENOG4107YJ4	chain length determinant protein
BBB49_14395	ENOG4105HTX	biosynthesis protein
BBB49_14405	ENOG4105EKQ	RNA-directed DNA polymerase
BBB49_14410	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BBB49_14490	ENOG4108KBE	Glycosyl transferase, family 2
BBB49_14500	ENOG4106YN8	Prenyltransferase
BBB49_14510	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BBB49_14525	ENOG4105EY8	ABC transporter
BBB49_14540	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BBB49_14555	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BBB49_14650	ENOG4105BZU	Histidine kinase
BBB49_14655	ENOG4105BZU	Histidine kinase
BBB49_14660	ENOG4105E71	FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off
BBB49_14665	ENOG4105E2V	Glycosyltransferase 36
BBB49_14670	ENOG4108K2F	hydrolase Family 5
BBB49_14680	ENOG4105DFM	M18 family aminopeptidase
BBB49_14690	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBB49_14695	ENOG4105EEI	dihydropteroate synthase
BBB49_14700	ENOG4105KFW	domain protein
BBB49_14705	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BBB49_14715	ENOG4105C9K	Endothelin-converting enzyme 1
BBB49_14720	ENOG4105CDA	abc transporter atp-binding protein
BBB49_14725	ENOG4105E5Q	amino acid AbC transporter
BBB49_14730	ENOG4108HW3	(ABC) transporter
BBB49_14735	ENOG4105EEM	helicase
BBB49_14740	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BBB49_14750	ENOG4105C3F	Signal peptidase i
BBB49_14765	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BBB49_14785	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_14795	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BBB49_14815	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BBB49_14820	ENOG4105DY9	regulatoR
BBB49_14835	ENOG4105CH2	amidohydrolase
BBB49_14845	ENOG4108UQV	Membrane
BBB49_14850	ENOG4108Z5V	transcriptional regulator, merr family
BBB49_14865	ENOG4105WD1	Membrane
BBB49_14875	ENOG4105BZ1	(ABC) transporter
BBB49_14880	ENOG4108JJ9	ABC, transporter
BBB49_14885	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BBB49_14895	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BBB49_14900	ENOG4105C08	Histidine kinase
BBB49_14905	ENOG4107ZYR	domain protein
BBB49_14910	ENOG4105CZN	Potassium uptake protein
BBB49_14945	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BBB49_14970	ENOG4105CA9	Pyruvate kinase
BBB49_14990	ENOG4105C0B	DNA polymerase III (alpha subunit)
BBB49_15015	ENOG4105CIE	May be required for sporulation (By similarity)
BBB49_15020	ENOG4105CHW	UPF0052 protein
BBB49_15025	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BBB49_15030	ENOG4105D4A	Cell wall formation (By similarity)
BBB49_15035	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BBB49_15040	ENOG4105CJN	penicillin-binding protein
BBB49_15060	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BBB49_15075	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BBB49_15080	ENOG4105CAK	Cell division ATP-binding protein ftsE
BBB49_15095	ENOG4108HHA	Transketolase
BBB49_15100	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
BBB49_15115	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BBB49_15120	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BBB49_15130	ENOG4108UUM	single-stranded DNA-binding protein
BBB49_15135	ENOG4107U9T	Pfam:Ribonuclease_BN
BBB49_15140	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
BBB49_15150	ENOG4107QQG	Dehydrogenase
BBB49_15155	ENOG4105J5G	Transferase hexapeptide repeat containing protein
BBB49_15165	ENOG4105DVT	helicase
BBB49_15175	ENOG4105KRN	Transcriptional regulator, abrb family
BBB49_15185	ENOG41060K3	Methyltransferase
BBB49_15190	ENOG41068JE	domain protein
BBB49_15200	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
BBB49_15205	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
BBB49_15210	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BBB49_15240	ENOG4105D29	Helix-turn-helix type 11 domain protein
BBB49_15245	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
BBB49_15275	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BBB49_15295	ENOG4105CFC	Transporter
BBB49_15350	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BBB49_15410	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BBB49_15420	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BBB49_15460	ENOG4105C5Y	PTS System
BBB49_15470	ENOG4105CID	antiterminator
BBB49_15475	ENOG4105D9U	N-acetyltransferase
BBB49_15480	ENOG4105CUZ	uba thif-type nad fad binding protein
BBB49_15485	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BBB49_15495	ENOG4108JQ7	(ABC) transporter
BBB49_15500	ENOG4105C3U	ABC transporter
BBB49_15505	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BBB49_15525	ENOG4108JQ1	Dehydrogenase
BBB49_15530	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BBB49_15565	ENOG4105C6E	dna polymerase iii
BBB49_15575	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BBB49_15580	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BBB49_15585	ENOG4105ERH	Fumarylacetoacetate hydrolase
BBB49_15595	ENOG4107R0W	ABC transporter
BBB49_15600	ENOG4105CDA	abc transporter atp-binding protein
BBB49_15605	ENOG4105E5Q	amino acid AbC transporter
BBB49_15610	ENOG4107R0W	ABC transporter
BBB49_15615	ENOG4105HDK	L-asparaginase
BBB49_15625	ENOG4108JB8	alcohol dehydrogenase
BBB49_15630	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BBB49_15690	ENOG4107QMH	DNA methylase
BBB49_15720	ENOG4108Z6B	deaminase
BBB49_15725	ENOG4108JU6	CBS domain protein
BBB49_15735	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BBB49_15750	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
BBB49_15795	ENOG41067QW	Transcriptional regulator
BBB49_15800	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BBB49_15810	ENOG4108YZT	Adenosylcobinamide kinase
BBB49_15815	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
BBB49_15825	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
BBB49_15850	ENOG4105F3R	pts system mannose fructose sorbose family iid
BBB49_15855	ENOG4105ETZ	PTS System
BBB49_15860	ENOG4108UZY	PTS System
BBB49_15865	ENOG4105EP8	Glycosyl Hydrolase Family 88
BBB49_15875	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
BBB49_15890	ENOG4105C9K	Endothelin-converting enzyme 1
BBB49_15895	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BBB49_15900	ENOG4105E9Q	Acyl-transferase
BBB49_15905	ENOG4105C1J	atp-dependent rna helicase
BBB49_15915	ENOG4105ER2	Ompa motb domain protein
BBB49_15920	ENOG4105E14	MotA TolQ exbB proton channel
BBB49_15925	ENOG4105DQ6	Transposase
BBB49_15930	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BBB49_15940	ENOG4108YZA	Nitrogen regulatory protein pii
BBB49_15945	ENOG4105BZU	Histidine kinase
BBB49_15955	ENOG4105CHH	sulfate transporter
BBB49_15960	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BBB49_15965	ENOG4105EJ9	Membrane
BBB49_16020	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BBB49_16025	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
BBB49_16030	ENOG4105CS2	ec 3.2.1.21
BBB49_16035	ENOG4108S3Y	transcriptional regulator
BBB49_16040	ENOG4105CK1	PTS System
BBB49_16050	ENOG4105VCP	PTS System
BBB49_16055	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BBB49_16075	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BBB49_16080	ENOG4105CJ3	phosphate transporter
BBB49_16085	ENOG4107GRR	phosphate transport regulator
BBB49_16100	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BBB49_16105	ENOG4105Q2H	domain protein
BBB49_16135	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BBB49_16210	ENOG4105CBX	hi0933 family
BBB49_16220	ENOG4105C09	Bile acid
BBB49_16235	ENOG4105C6K	Malic enzyme
BBB49_16250	ENOG4105II7	pyrroline-5-carboxylate reductase
BBB49_16260	ENOG4105CDU	Replicative dna helicase
BBB49_16265	ENOG4108IUQ	atp-dependent protease
BBB49_16270	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BBB49_16275	ENOG4105BZR	domain protein
BBB49_16285	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BBB49_16290	ENOG4108UUM	single-stranded DNA-binding protein
BBB49_16295	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BBB49_16305	ENOG4105D8X	mechanosensitive ion channel
BBB49_16320	ENOG4105C9B	Cysteine desulfurase
BBB49_16325	ENOG4108ZDA	Sporulation protein YyaC
BBB49_16330	ENOG4105DQ6	Transposase
BBB49_16340	ENOG4105FA0	parb-like partition protein
BBB49_16345	ENOG4107QJE	Chromosome Partitioning Protein
BBB49_16360	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BBB49_16365	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BBB49_16380	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BBB49_16385	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BBB49_16390	ENOG4105VG0	50S ribosomal protein l34
BBB49_16400	ENOG4105BZU	Histidine kinase
BBB49_16405	ENOG4108V4M	Cobalt abc transporter
BBB49_16410	ENOG4108JJB	ABC transporter
BBB49_16415	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BBB49_16425	ENOG4108V06	Glutathione peroxidase
BBB49_16430	ENOG4108V06	Glutathione peroxidase
BBB49_16450	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BBB49_16485	ENOG4105MAX	Superoxide reductase
BBB49_16495	ENOG4108PJD	permease
BBB49_16505	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
BBB49_16525	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBB49_16535	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
BBB49_16555	ENOG4105D6U	Sodium Glutamate Symporter
BBB49_16560	ENOG4105C22	threonyL-tRNA synthetase
BBB49_16565	ENOG4105DDN	Pentapeptide repeat-containing protein
BBB49_16585	ENOG4108JJB	ABC transporter
BBB49_16610	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BBB49_16615	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
BBB49_16620	ENOG4105CPC	Aldo Keto reductase
BBB49_16630	ENOG4108MES	Periplasmic binding protein
BBB49_16635	ENOG4105DQ5	transport system permease protein
BBB49_16640	ENOG4105EHG	Permease protein
BBB49_16645	ENOG4105E0A	ABC, transporter
BBB49_16655	ENOG4108Z5V	transcriptional regulator, merr family
BBB49_16660	ENOG4105BZ1	(ABC) transporter
BBB49_16665	ENOG4105BZ1	(ABC) transporter
BBB49_16680	ENOG4105C2W	permease
BBB49_16685	ENOG4105DNP	FAD linked oxidase domain protein
BBB49_16690	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BBB49_16695	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BBB49_16700	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BBB49_16705	ENOG4105WH1	Two component transcriptional regulator luxr family
BBB49_16745	ENOG4105ETZ	PTS System
BBB49_16750	ENOG4105F3R	pts system mannose fructose sorbose family iid
BBB49_16770	ENOG4105BZU	Histidine kinase
BBB49_16775	ENOG4108UZ3	Transporter
BBB49_16780	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_16810	ENOG4105C2J	ABC transporter
BBB49_16815	ENOG4105CNN	ABC, transporter
BBB49_16820	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
BBB49_16830	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BBB49_16835	ENOG4105ETE	Transcriptional regulator (LacI family
BBB49_16840	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
BBB49_16845	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BBB49_16855	ENOG4105BZU	Histidine kinase
BBB49_16860	ENOG4105VYW	UPF0251 protein
BBB49_16875	ENOG4108IUW	ABC transporter
BBB49_16905	ENOG4107S6X	Glycosyl transferase, family 2
BBB49_16910	ENOG4105CF7	AraC family transcriptional regulator
BBB49_16915	ENOG4105BZ1	(ABC) transporter
BBB49_16920	ENOG4105BZ1	(ABC) transporter
BBB49_16945	ENOG4105DND	Transcriptional regulator
BBB49_16950	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BBB49_16985	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BBB49_16995	ENOG4105F4R	Transcriptional regulator mode
BBB49_17000	ENOG4108IJ6	ABC transporter
BBB49_17005	ENOG4105E0C	molybdate abc transporter
BBB49_17010	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BBB49_17025	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
BBB49_17040	ENOG4108YZA	Nitrogen regulatory protein pii
BBB49_17060	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
BBB49_17065	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
BBB49_17085	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BBB49_17090	ENOG4105T16	Transcriptional regulator (AraC family)
BBB49_17110	ENOG4105VDH	Dihydroxyacetone kinase
BBB49_17115	ENOG4108HRK	Histidine kinase
BBB49_17120	ENOG41075H3	AraC family transcriptional regulator
BBB49_17125	ENOG4105C6N	Formate acetyltransferase
BBB49_17140	ENOG4105D3R	alkyl hydroperoxide reductase
BBB49_17155	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
BBB49_17230	ENOG4105E98	transcriptional regulator DeoR family
BBB49_17235	ENOG4105F1A	Pyruvate formate-lyase
BBB49_17240	ENOG4105C6N	Formate acetyltransferase
BBB49_17250	ENOG4108Q3X	Transcriptional regulator
BBB49_17255	ENOG4105DM4	PTS System
BBB49_17260	ENOG4105C8I	hydrolase, family 38
BBB49_17265	ENOG4108MCI	Transcriptional regulator, ARAC family
BBB49_17290	ENOG4105HX0	Transcriptional regulator
BBB49_17300	ENOG4105C5Y	PTS System
BBB49_17320	ENOG4105DSG	hydrolase family 43
BBB49_17330	ENOG4108QTI	)-transporter
BBB49_17335	ENOG4105C6N	Formate acetyltransferase
BBB49_17340	ENOG4105F1A	Pyruvate formate-lyase
BBB49_17350	ENOG4105CJ1	ABC, transporter
BBB49_17370	ENOG4105VUF	Transcriptional regulator
BBB49_17380	ENOG4107RSM	transcriptional regulator
BBB49_17400	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
BBB49_17415	ENOG4105X5K	response regulator receiver protein
BBB49_17435	ENOG410667J	hydrolase
BBB49_17445	ENOG4105CJW	magnesium transporter
BBB49_17485	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BBB49_17490	ENOG4107Y3V	-acetyltransferase
BBB49_17505	ENOG4105DND	Transcriptional regulator
BBB49_17510	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
BBB49_17515	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BBB49_17550	ENOG4105CI1	PTS System
BBB49_17560	ENOG4107YX5	Pfam:DUF548
BBB49_17590	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BBB49_17595	ENOG4105ETE	Transcriptional regulator (LacI family
BBB49_17600	ENOG4107QMU	Mate efflux family protein
BBB49_17605	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
BBB49_17615	ENOG41067MG	lrgb family
BBB49_17625	ENOG41073TP	transcriptional regulator
BBB49_17630	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BBB49_17640	ENOG4108IY8	ABC, transporter
BBB49_17650	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
BBB49_17655	ENOG4107XKF	NMT1 THI5 Like Domain Protein
BBB49_17665	ENOG4107SJI	Dehydrogenase
BBB49_17675	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BBB49_17680	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BBB49_17695	ENOG4105BZU	Histidine kinase
BBB49_17710	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BBB49_17720	ENOG4108Q3X	Transcriptional regulator
BBB49_17725	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BBB49_17735	ENOG4105BZU	Histidine kinase
BBB49_17750	ENOG4105G0J	serine threonine protein kinase
BBB49_17760	ENOG4105C5Y	PTS System
BBB49_17765	ENOG4105CG3	alpha amylase, catalytic region
BBB49_17770	ENOG4107414	GntR family transcriptional regulator
BBB49_17775	ENOG4105CNW	domain protein
BBB49_17780	ENOG4105DQR	SNARE associated Golgi
BBB49_17790	ENOG4105D5G	Transposase
BBB49_17810	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
BBB49_17820	ENOG4105BZU	Histidine kinase
BBB49_17825	ENOG4107XVH	Transcriptional regulator
BBB49_17830	ENOG4105CHR	reductase
BBB49_17840	ENOG41081I9	integral membrane protein
BBB49_17850	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BBB49_17855	ENOG4107TXC	Transcriptional regulator
BBB49_17890	ENOG4107RRE	RNA-directed DNA polymerase
BBB49_17905	ENOG4105BZ1	(ABC) transporter
BBB49_17910	ENOG4105BZ1	(ABC) transporter
BBB49_17940	ENOG4105I03	Flagellin
BBB49_17945	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BBB49_17950	ENOG4105EAM	Na Pi-cotransporter
BBB49_17960	ENOG4105DQ6	Transposase
BBB49_17965	ENOG4105G9B	Transcriptional regulator
BBB49_17975	ENOG4105S0E	allantoin catabolism protein
BBB49_17980	ENOG4105C5I	Dehydrogenase
BBB49_18000	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBB49_18010	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
BBB49_18020	ENOG4105C8Q	Methyl-accepting chemotaxis
BBB49_18025	ENOG4105CDW	Resistance protein
BBB49_18035	ENOG4105C3S	Mate efflux family protein
BBB49_18045	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
BBB49_18055	ENOG4108W2Y	isochorismatase
BBB49_18065	ENOG4105KVH	Transcriptional regulator
BBB49_18080	ENOG4105C5I	Dehydrogenase
BBB49_18090	ENOG4108U5J	'-nucleotidase
BBB49_18110	ENOG4105BZU	Histidine kinase
BBB49_18130	ENOG4107QM2	Aldo Keto reductase
BBB49_18135	ENOG4106KNT	transcriptional regulator
BBB49_18145	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BBB49_18150	ENOG4105RD7	BadF BadG BcrA BcrD
BBB49_18165	ENOG4105VCP	PTS System
BBB49_18170	ENOG4105F8D	glycoside hydrolase family 4
BBB49_18175	ENOG4105CK1	PTS System
BBB49_18180	ENOG4105VZJ	PTS System
BBB49_18200	ENOG4107TXC	Transcriptional regulator
BBB49_18235	ENOG4107RN3	metallophosphoesterase
BBB49_18255	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BBB49_18260	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BBB49_18265	ENOG4108MDK	Dehydrogenase
BBB49_18275	ENOG4105CB5	ATP-dependent DNA helicase recG
BBB49_18285	ENOG4108TVT	permease
BBB49_18305	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BBB49_18310	ENOG4107S1Q	Phosphatase
BBB49_18315	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BBB49_18325	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
BBB49_18365	ENOG4105G7B	Protein of unknown function (DUF2992)
BBB49_18385	ENOG4107QJQ	Mate efflux family protein
BBB49_18395	ENOG4105DQR	SNARE associated Golgi
BBB49_18415	ENOG4105UIB	(ABC) transporter
BBB49_18420	ENOG4108JQ9	ABC transporter
BBB49_18430	ENOG4106IUH	DTW domain containing protein
BBB49_18440	ENOG41082BM	Transcriptional regulator, arsr family
BBB49_18445	ENOG4108589	degv family
BBB49_18450	ENOG4105EJ2	Transcriptional regulator
BBB49_18455	ENOG410667J	hydrolase
BBB49_18465	ENOG4105F3R	pts system mannose fructose sorbose family iid
BBB49_18490	ENOG4105WH1	Two component transcriptional regulator luxr family
BBB49_18495	ENOG4105BZU	Histidine kinase
BBB49_18515	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
BBB49_18520	ENOG4105CT1	(ABC) transporter
BBB49_18525	ENOG4105CDA	abc transporter atp-binding protein
BBB49_18530	ENOG4105DRP	amino acid AbC transporter
BBB49_18535	ENOG4105E5Q	amino acid AbC transporter
BBB49_18540	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
BBB49_18545	ENOG4105CK2	sodium dicarboxylate symporter
BBB49_18550	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
BBB49_18555	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BBB49_18560	ENOG4105E0C	molybdate abc transporter
BBB49_18565	ENOG4108IJ6	ABC transporter
BBB49_18570	ENOG4105ETE	Transcriptional regulator (LacI family
BBB49_18575	ENOG4105VCP	PTS System
BBB49_18580	ENOG4105CK1	PTS System
BBB49_18590	ENOG4105CS2	ec 3.2.1.21
BBB49_18595	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
BBB49_18605	ENOG4107KJX	Transcriptional regulator
BBB49_18620	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
BBB49_18635	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
BBB49_18640	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BBB49_18645	ENOG4107UUR	Chlorohydrolase aminohydrolase
BBB49_18670	ENOG4107RCH	Diaminopropionate ammonia-lyase
BBB49_18675	ENOG4107QUY	Guanine deaminase
BBB49_18680	ENOG4105BZ1	(ABC) transporter
BBB49_18700	ENOG4105DRS	transport system, permease
BBB49_18705	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BBB49_18710	ENOG4108JE9	extracellular solute-binding protein family 1
BBB49_18715	ENOG4108HCJ	Hydrolase
BBB49_18720	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
BBB49_18735	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BBB49_18750	ENOG4108XXK	NUDIX hydrolase
BBB49_18755	ENOG4105JMH	Nadph-dependent fmn reductase
BBB49_18770	ENOG4107XGZ	Hydrolase
BBB49_18800	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BBB49_18805	ENOG4105CW7	secretion protein, HlyD family
BBB49_18820	ENOG4107DB1	DUF218 domain
BBB49_18835	ENOG4108ZJ4	polysaccharide deacetylase
BBB49_18845	ENOG4108R5S	membrane
BBB49_18860	ENOG4105C87	Aminotransferase class I and II
BBB49_18870	ENOG4108W5M	transcriptional regulator
BBB49_18900	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
BBB49_18905	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
BBB49_18915	ENOG4105DTT	CRISPR-associated helicase, cas3
BBB49_18975	ENOG4105DY9	regulatoR
BBB49_18985	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BBB49_18990	ENOG4105BZU	Histidine kinase
BBB49_18995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_19010	ENOG4105C4C	beta-galactosidase
BBB49_19025	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BBB49_19035	ENOG4107VQW	regulatoR
BBB49_19040	ENOG4105C2F	Histidine kinase
BBB49_19150	ENOG410685N	tail fiber protein
BBB49_19330	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BBB49_19440	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BBB49_19455	ENOG4105KRN	Transcriptional regulator, abrb family
BBB49_19515	ENOG4105E0A	ABC, transporter
BBB49_19520	ENOG4105EHG	Permease protein
BBB49_19525	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
BBB49_19530	ENOG4107QJQ	Mate efflux family protein
BBB49_19540	ENOG4108MCI	Transcriptional regulator, ARAC family
BBB49_19550	ENOG4108Q3X	Transcriptional regulator
BBB49_19555	ENOG4108Q3X	Transcriptional regulator
BBB49_19560	ENOG4105CI1	PTS System
BBB49_19565	ENOG4105F8D	glycoside hydrolase family 4
BBB49_19585	ENOG4105KVH	Transcriptional regulator
BBB49_19630	ENOG4107S9D	Alpha beta hydrolase
BBB49_19635	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BBB49_19640	ENOG4105D9R	oxidoreductase
BBB49_19645	ENOG4105EE0	oxidoreductase
BBB49_19655	ENOG4108JJB	ABC transporter
BBB49_19660	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BBB49_19665	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BBB49_19675	ENOG4105C8M	UPF0272 protein
BBB49_19680	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
BBB49_19705	ENOG4105BZ1	(ABC) transporter
BBB49_19710	ENOG4105BZ1	(ABC) transporter
BBB49_19715	ENOG4105DBA	pectate lyase
BBB49_19735	ENOG4105KVH	Transcriptional regulator
BBB49_19745	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BBB49_19760	ENOG4105E2R	ROK family
BBB49_19765	ENOG4105CMG	Carbohydrate kinase
BBB49_19770	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BBB49_19820	ENOG4105BZU	Histidine kinase
BBB49_19825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_19830	ENOG4108J2R	molybdopterin oxidoreductase
BBB49_19835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BBB49_19840	ENOG4105BZU	Histidine kinase
BBB49_19855	ENOG4105E66	phosphoriboisomerase A
BBB49_19865	ENOG4105C8Q	Methyl-accepting chemotaxis