locus-tag	class	description
BBB49_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBB49_00010	COG0592	DNA-directed DNA polymerase activity
BBB49_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBB49_00030	COG0187	DNA topoisomerase II activity
BBB49_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBB49_00075	COG1827	regulation of RNA biosynthetic process
BBB49_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBB49_00120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BBB49_00125	COG1074	ATP-dependent DNA helicase activity
BBB49_00130	COG1376	ErfK ybiS ycfS ynhG family protein
BBB49_00145	COG2205	protein histidine kinase activity
BBB49_00145	COG0784	Response regulator, receiver
BBB49_00160	COG0688	phosphatidylethanolamine metabolic process
BBB49_00165	COG1309	transcriptional regulator
BBB49_00175	COG0561	phosphatase activity
BBB49_00180	COG0488	(ABC) transporter
BBB49_00210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBB49_00220	COG3290	protein histidine kinase activity
BBB49_00220	COG0840	transmembrane signaling receptor activity
BBB49_00255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBB49_00270	COG3584	3D domain protein
BBB49_00270	COG3583	domain protein
BBB49_00290	COG3949	Membrane
BBB49_00295	COG1242	4 iron, 4 sulfur cluster binding
BBB49_00300	COG2045	Belongs to the ComB family
BBB49_00320	COG0745	RESPONSE REGULATOR receiver
BBB49_00325	COG5002	protein histidine kinase activity
BBB49_00365	COG0534	Mate efflux family protein
BBB49_00375	COG2715	membrane protein required for spore maturation
BBB49_00380	COG0700	Nucleoside recognition
BBB49_00385	COG0006	proline dipeptidase activity
BBB49_00390	COG1757	Na H antiporter
BBB49_00405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBB49_00410	COG0084	hydrolase, TatD family'
BBB49_00415	COG3583	domain protein
BBB49_00415	COG3584	3D domain protein
BBB49_00420	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BBB49_00425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BBB49_00455	COG1141	Ferredoxin
BBB49_00470	COG1307	EDD domain protein, DegV family
BBB49_00475	COG1328	CTP reductase activity
BBB49_00480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBB49_00485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBB49_00490	COG0602	queuosine metabolic process
BBB49_00500	COG2094	Belongs to the DNA glycosylase MPG family
BBB49_00520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBB49_00525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBB49_00530	COG2088	sporulation resulting in formation of a cellular spore
BBB49_00535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBB49_00545	COG0745	RESPONSE REGULATOR receiver
BBB49_00550	COG5002	protein histidine kinase activity
BBB49_00550	COG3850	Histidine kinase
BBB49_00555	COG0193	aminoacyl-tRNA hydrolase activity
BBB49_00560	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBB49_00570	COG2002	toxin-antitoxin pair type II binding
BBB49_00575	COG2244	polysaccharide biosynthetic process
BBB49_00580	COG3956	TIGRFAM MazG family protein
BBB49_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BBB49_00610	COG1098	S1 RNA binding domain
BBB49_00665	COG2208	phosphoserine phosphatase activity
BBB49_00670	COG0037	tRNA processing
BBB49_00680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBB49_00685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BBB49_00690	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BBB49_00695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBB49_00700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBB49_00705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBB49_00730	COG0423	glycine-tRNA ligase activity
BBB49_00735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBB49_00795	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBB49_00800	COG3870	Protein conserved in bacteria
BBB49_00810	COG1774	PSP1 C-terminal conserved region
BBB49_00825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBB49_00835	COG3880	PFAM UvrB UvrC protein
BBB49_00845	COG0542	response to heat
BBB49_00865	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBB49_00870	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BBB49_00880	COG4956	integral membrane protein (PIN domain superfamily)
BBB49_00885	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BBB49_00890	COG0442	prolyl-tRNA aminoacylation
BBB49_00895	COG0215	cysteine-tRNA ligase activity
BBB49_00905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBB49_00925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBB49_00930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBB49_00935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBB49_00940	COG0250	Participates in transcription elongation, termination and antitermination
BBB49_00945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BBB49_00950	COG0081	regulation of translation
BBB49_00960	COG0222	ribosome binding
BBB49_00970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBB49_00985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBB49_00990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBB49_00995	COG0051	transcription antitermination factor activity, RNA binding
BBB49_01000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBB49_01005	COG0088	Forms part of the polypeptide exit tunnel
BBB49_01010	COG0089	rRNA binding
BBB49_01015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBB49_01020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBB49_01025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBB49_01030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBB49_01035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBB49_01040	COG0255	Belongs to the universal ribosomal protein uL29 family
BBB49_01045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBB49_01050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBB49_01055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBB49_01060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBB49_01070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBB49_01075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBB49_01080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBB49_01085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BBB49_01090	COG1841	ribosomal large subunit assembly
BBB49_01095	COG0200	Binds to the 23S rRNA
BBB49_01100	COG0201	protein transport
BBB49_01105	COG0563	adenylate kinase activity
BBB49_01120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBB49_01125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BBB49_01130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBB49_01135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBB49_01140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBB49_01145	COG0202	RNA polymerase activity
BBB49_01150	COG0203	ribosomal protein L17
BBB49_01155	COG1122	ATPase activity
BBB49_01160	COG1122	ATPase activity
BBB49_01165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBB49_01170	COG0101	tRNA pseudouridine synthase activity
BBB49_01175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBB49_01185	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBB49_01190	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBB49_01195	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BBB49_01195	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BBB49_01205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBB49_01225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBB49_01230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBB49_01235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBB49_01245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBB49_01250	COG3773	Cell wall hydrolase
BBB49_01250	COG3409	Peptidoglycan-binding domain 1 protein
BBB49_01255	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBB49_01265	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BBB49_01270	COG0280	phosphate acetyltransferase
BBB49_01290	COG0840	transmembrane signaling receptor activity
BBB49_01295	COG0534	Mate efflux family protein
BBB49_01320	COG4496	protein, YerC YecD
BBB49_01325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBB49_01335	COG0440	acetolactate synthase activity
BBB49_01340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBB49_01345	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBB49_01350	COG0066	3-isopropylmalate dehydratase activity
BBB49_01355	COG0473	3-isopropylmalate dehydrogenase activity
BBB49_01365	COG0028	Belongs to the TPP enzyme family
BBB49_01395	COG1609	Transcriptional regulator
BBB49_01400	COG0366	Alpha amylase catalytic
BBB49_01405	COG2190	(PTS) system
BBB49_01405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_01405	COG1263	PTS System
BBB49_01450	COG1349	DNA-binding transcription factor activity
BBB49_01465	COG3775	system Galactitol-specific IIC component
BBB49_01470	COG0698	ribose 5-phosphate isomerase
BBB49_01480	COG0191	fructose-bisphosphate aldolase activity
BBB49_01485	COG1105	Belongs to the carbohydrate kinase PfkB family
BBB49_01495	COG0288	reversible hydration of carbon dioxide
BBB49_01500	COG0616	signal peptide processing
BBB49_01515	COG0058	SHG alpha-glucan phosphorylase activity
BBB49_01520	COG2207	Transcriptional regulator
BBB49_01520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBB49_01525	COG0366	Alpha amylase catalytic
BBB49_01530	COG2116	formate transmembrane transporter activity
BBB49_01540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBB49_01575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BBB49_01585	COG0726	polysaccharide deacetylase
BBB49_01595	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBB49_01605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB49_01610	COG2086	electron transfer activity
BBB49_01615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBB49_01620	COG0277	FAD linked oxidase domain protein
BBB49_01625	COG0653	protein targeting
BBB49_01640	COG0745	RESPONSE REGULATOR receiver
BBB49_01645	COG3850	Histidine kinase
BBB49_01645	COG5002	protein histidine kinase activity
BBB49_01665	COG0662	Cupin 2, conserved barrel domain protein
BBB49_01665	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BBB49_01680	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BBB49_01680	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BBB49_01685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBB49_01690	COG1447	Phosphotransferase system cellobiose-specific component IIA
BBB49_01695	COG2971	BadF BadG BcrA BcrD
BBB49_01705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBB49_01715	COG0640	Transcriptional regulator
BBB49_01720	COG2217	Heavy metal translocating P-type atpase
BBB49_01730	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BBB49_01735	COG1024	Enoyl-CoA hydratase
BBB49_01740	COG1960	acyl-CoA dehydrogenase activity
BBB49_01745	COG2086	electron transfer activity
BBB49_01755	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB49_01775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBB49_01780	COG0459	protein refolding
BBB49_01790	COG0516	GMP reductase activity
BBB49_01790	COG0517	IMP dehydrogenase activity
BBB49_01805	COG1595	DNA-templated transcription, initiation
BBB49_01830	COG0166	Belongs to the GPI family
BBB49_01845	COG0741	lytic transglycosylase activity
BBB49_01850	COG1187	pseudouridine synthase activity
BBB49_01860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBB49_01890	COG4166	transmembrane transport
BBB49_02010	COG2207	Transcriptional regulator
BBB49_02010	COG1917	Cupin 2, conserved barrel domain protein
BBB49_02025	COG5426	von Willebrand factor, type A
BBB49_02030	COG1653	transport
BBB49_02035	COG2971	BadF BadG BcrA BcrD
BBB49_02045	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_02050	COG3715	PTS system
BBB49_02055	COG3716	PTS system mannose fructose sorbose family IID component
BBB49_02065	COG2222	sugar isomerase
BBB49_02115	COG3590	peptidase
BBB49_02150	COG1595	DNA-templated transcription, initiation
BBB49_02160	COG0312	modulator of DNA gyrase
BBB49_02165	COG0312	modulator of DNA gyrase
BBB49_02190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBB49_02200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBB49_02205	COG1447	Phosphotransferase system cellobiose-specific component IIA
BBB49_02255	COG4466	Protein conserved in bacteria
BBB49_02260	COG0791	NLP P60 protein
BBB49_02260	COG1388	LysM domain
BBB49_02265	COG4242	Belongs to the peptidase S51 family
BBB49_02275	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBB49_02300	COG0504	CTP synthase activity
BBB49_02305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBB49_02310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBB49_02315	COG0254	rRNA binding
BBB49_02320	COG1435	thymidine kinase activity
BBB49_02330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBB49_02340	COG0009	L-threonylcarbamoyladenylate synthase
BBB49_02345	COG0698	ribose 5-phosphate isomerase
BBB49_02350	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBB49_02360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBB49_02365	COG0183	Belongs to the thiolase family
BBB49_02380	COG0356	it plays a direct role in the translocation of protons across the membrane
BBB49_02385	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBB49_02390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BBB49_02410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBB49_02430	COG2385	sporulation resulting in formation of a cellular spore
BBB49_02440	COG1609	Transcriptional regulator
BBB49_02515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBB49_02525	COG1040	competence protein
BBB49_02530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBB49_02535	COG0653	protein targeting
BBB49_02540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBB49_02560	COG5002	protein histidine kinase activity
BBB49_02570	COG2183	response to ionizing radiation
BBB49_02585	COG0456	acetyltransferase
BBB49_02590	COG1214	PFAM Peptidase M22, glycoprotease
BBB49_02595	COG0802	atpase or kinase
BBB49_02620	COG0251	oxidation-reduction process
BBB49_02655	COG0803	Belongs to the bacterial solute-binding protein 9 family
BBB49_02665	COG0670	Belongs to the BI1 family
BBB49_02670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBB49_02685	COG0539	negative regulation of cytoplasmic translation
BBB49_02685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBB49_02695	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBB49_02710	COG0424	maF-like protein
BBB49_02715	COG2003	Belongs to the UPF0758 family
BBB49_02720	COG1077	Cell shape determining protein MreB Mrl
BBB49_02725	COG1792	Involved in formation and maintenance of cell shape
BBB49_02740	COG1489	DNA binding
BBB49_02750	COG2894	cell division
BBB49_02755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BBB49_02760	COG0772	Belongs to the SEDS family
BBB49_02790	COG1530	ribonuclease E activity
BBB49_02795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BBB49_02805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BBB49_02810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBB49_02815	COG1534	Rna-binding protein
BBB49_02820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBB49_02825	COG1713	HD superfamily hydrolase involved in NAD metabolism
BBB49_02830	COG1316	TRANSCRIPTIONal
BBB49_02835	COG0564	pseudouridine synthase activity
BBB49_02840	COG1686	Belongs to the peptidase S11 family
BBB49_02845	COG1555	photosystem II stabilization
BBB49_02875	COG0772	Belongs to the SEDS family
BBB49_02885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BBB49_02890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBB49_02895	COG1442	glycosyl transferase family 8
BBB49_02900	COG1216	Glycosyl transferase, family 2
BBB49_02905	COG1442	glycosyl transferase family 8
BBB49_02915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBB49_02920	COG2766	serine protein kinase
BBB49_02925	COG2718	Belongs to the UPF0229 family
BBB49_02930	COG2719	SpoVR family
BBB49_02935	COG1592	Rubrerythrin
BBB49_02950	COG1183	phosphatidylcholine synthase activity
BBB49_02955	COG1597	lipid kinase activity
BBB49_02975	COG2239	Acts as a magnesium transporter
BBB49_02980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBB49_02985	COG1045	serine acetyltransferase
BBB49_02990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBB49_03000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBB49_03005	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBB49_03015	COG5002	protein histidine kinase activity
BBB49_03025	COG2720	vancomycin resistance protein
BBB49_03030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBB49_03040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BBB49_03045	COG2390	Transcriptional regulator
BBB49_03050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BBB49_03055	COG0126	phosphoglycerate kinase activity
BBB49_03060	COG0149	triose-phosphate isomerase activity
BBB49_03065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBB49_03080	COG0148	phosphopyruvate hydratase activity
BBB49_03090	COG3152	Membrane
BBB49_03110	COG0557	exoribonuclease II activity
BBB49_03115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BBB49_03120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBB49_03125	COG2011	ABC-type metal ion transport system permease component
BBB49_03130	COG1464	Belongs to the NlpA lipoprotein family
BBB49_03165	COG2376	Dihydroxyacetone kinase
BBB49_03200	COG2205	protein histidine kinase activity
BBB49_03205	COG0745	RESPONSE REGULATOR receiver
BBB49_03215	COG4684	Psort location CytoplasmicMembrane, score
BBB49_03225	COG0037	tRNA processing
BBB49_03250	COG2233	PERMEase
BBB49_03255	COG2199	diguanylate cyclase activity
BBB49_03255	COG2203	Gaf domain
BBB49_03265	COG0756	dUTP diphosphatase activity
BBB49_03270	COG0488	(ABC) transporter
BBB49_03275	COG1309	transcriptional regulator
BBB49_03290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBB49_03295	COG0205	6-phosphofructokinase activity
BBB49_03300	COG1971	Probably functions as a manganese efflux pump
BBB49_03305	COG0735	belongs to the Fur family
BBB49_03310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBB49_03315	COG1121	(ABC) transporter
BBB49_03320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BBB49_03330	COG1696	Membrane protein involved in D-alanine export
BBB49_03335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBB49_03350	COG1164	Oligoendopeptidase f
BBB49_03355	COG0457	Tetratricopeptide repeat
BBB49_03355	COG0705	Rhomboid family
BBB49_03365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBB49_03370	COG1215	transferase activity, transferring glycosyl groups
BBB49_03375	COG0187	DNA topoisomerase II activity
BBB49_03380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBB49_03390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBB49_03390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBB49_03395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBB49_03400	COG0655	NAD(P)H dehydrogenase (quinone) activity
BBB49_03415	COG0436	Aminotransferase
BBB49_03435	COG0835	chemotaxis
BBB49_03445	COG2201	protein-glutamate methylesterase activity
BBB49_03450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBB49_03455	COG2198	Histidine kinase
BBB49_03455	COG0643	Histidine kinase
BBB49_03460	COG1776	CheC inhibitor of MCP methylation
BBB49_03465	COG2201	protein-glutamate methylesterase activity
BBB49_03475	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBB49_03480	COG1776	CheC inhibitor of MCP methylation
BBB49_03480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBB49_03500	COG4786	Flagellar basal body rod
BBB49_03500	COG1256	bacterial-type flagellum assembly
BBB49_03505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBB49_03510	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BBB49_03515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBB49_03535	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBB49_03555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBB49_03560	COG1815	bacterial-type flagellum-dependent cell motility
BBB49_03570	COG1677	Flagellar hook-basal body complex protein FliE
BBB49_03575	COG1766	The M ring may be actively involved in energy transduction
BBB49_03580	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBB49_03590	COG1157	protein secretion by the type III secretion system
BBB49_03615	COG4786	Flagellar basal body rod
BBB49_03620	COG4786	Flagellar basal body rod
BBB49_03625	COG1582	Flagellar protein (FlbD)
BBB49_03650	COG1338	Plays a role in the flagellum-specific transport system
BBB49_03660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBB49_03665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBB49_03670	COG1419	protein localization to endoplasmic reticulum
BBB49_03675	COG0455	bacterial-type flagellum organization
BBB49_03685	COG1191	sigma factor activity
BBB49_03695	COG4786	Flagellar basal body rod
BBB49_03700	COG4786	Flagellar basal body rod
BBB49_03715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBB49_03730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBB49_03735	COG1067	ATP-dependent peptidase activity
BBB49_03745	COG2172	sigma factor antagonist activity
BBB49_03760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBB49_03770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBB49_03785	COG0268	Binds directly to 16S ribosomal RNA
BBB49_03790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BBB49_03815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBB49_03820	COG1420	regulation of RNA biosynthetic process
BBB49_03825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBB49_03830	COG0443	Heat shock 70 kDa protein
BBB49_03835	COG0484	heat shock protein binding
BBB49_03850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBB49_03860	COG2264	protein methyltransferase activity
BBB49_03865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBB49_03870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBB49_03875	COG0537	adenosine 5'-monophosphoramidase activity
BBB49_03885	COG1610	YqeY-like protein
BBB49_03900	COG1480	7TM receptor with intracellular HD hydrolase
BBB49_03910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBB49_03915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBB49_03930	COG0517	IMP dehydrogenase activity
BBB49_03935	COG0574	Belongs to the PEP-utilizing enzyme family
BBB49_03935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBB49_03950	COG0358	DNA primase activity
BBB49_03955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBB49_03985	COG3842	ATPase activity
BBB49_03990	COG3835	regulator
BBB49_04005	COG0058	SHG alpha-glucan phosphorylase activity
BBB49_04010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBB49_04015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBB49_04055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBB49_04075	COG0493	'glutamate synthase
BBB49_04085	COG3118	belongs to the thioredoxin family
BBB49_04090	COG1846	Transcriptional regulator
BBB49_04095	COG1114	Component of the transport system for branched-chain amino acids
BBB49_04110	COG1349	DNA-binding transcription factor activity
BBB49_04120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BBB49_04140	COG1151	hydroxylamine reductase activity
BBB49_04150	COG1131	(ABC) transporter
BBB49_04155	COG1725	Transcriptional regulator
BBB49_04170	COG0157	Belongs to the NadC ModD family
BBB49_04175	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBB49_04200	COG0726	polysaccharide deacetylase
BBB49_04225	COG0745	RESPONSE REGULATOR receiver
BBB49_04230	COG2205	protein histidine kinase activity
BBB49_04235	COG1136	(ABC) transporter
BBB49_04245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBB49_04245	COG2199	diguanylate cyclase activity
BBB49_04260	COG0840	transmembrane signaling receptor activity
BBB49_04265	COG0612	Peptidase, M16
BBB49_04270	COG1982	Orn Lys Arg decarboxylase major
BBB49_04275	COG0733	neurotransmitter:sodium symporter activity
BBB49_04280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BBB49_04285	COG0542	response to heat
BBB49_04295	COG1522	sequence-specific DNA binding
BBB49_04300	COG0436	Aminotransferase
BBB49_04310	COG1744	ABC transporter substrate-binding protein PnrA-like
BBB49_04330	COG0295	cytidine deaminase activity
BBB49_04335	COG0813	purine-nucleoside phosphorylase activity
BBB49_04350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBB49_04355	COG3437	response regulator, receiver
BBB49_04360	COG2801	Transposase and inactivated derivatives
BBB49_04365	COG2267	carboxylic ester hydrolase activity
BBB49_04370	COG1393	Belongs to the ArsC family
BBB49_04375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBB49_04380	COG2059	Chromate
BBB49_04395	COG4086	secreted protein
BBB49_04400	COG0366	Alpha amylase catalytic
BBB49_04405	COG1523	belongs to the glycosyl hydrolase 13 family
BBB49_04415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BBB49_04425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB49_04435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBB49_04440	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BBB49_04450	COG1321	iron dependent repressor
BBB49_04485	COG0733	neurotransmitter:sodium symporter activity
BBB49_04490	COG0436	Aminotransferase
BBB49_04495	COG1846	Transcriptional regulator
BBB49_04505	COG1522	sequence-specific DNA binding
BBB49_04520	COG4336	lyase activity
BBB49_04525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBB49_04530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBB49_04535	COG1984	allophanate hydrolase subunit 2
BBB49_04540	COG0511	ligase activity, forming carbon-carbon bonds
BBB49_04545	COG0439	Biotin carboxylase
BBB49_04570	COG0028	Belongs to the TPP enzyme family
BBB49_04570	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BBB49_04575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BBB49_04590	COG3290	protein histidine kinase activity
BBB49_04605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBB49_04605	COG0493	'glutamate synthase
BBB49_04610	COG2172	sigma factor antagonist activity
BBB49_04615	COG0840	transmembrane signaling receptor activity
BBB49_04645	COG1063	alcohol dehydrogenase
BBB49_04655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBB49_04655	COG0493	'glutamate synthase
BBB49_04660	COG2814	Major facilitator Superfamily
BBB49_04670	COG3142	Participates in the control of copper homeostasis
BBB49_04675	COG0642	Histidine kinase
BBB49_04675	COG5002	protein histidine kinase activity
BBB49_04680	COG0745	RESPONSE REGULATOR receiver
BBB49_04685	COG0398	Pfam SNARE associated Golgi protein
BBB49_04690	COG1183	phosphatidylcholine synthase activity
BBB49_04695	COG3290	protein histidine kinase activity
BBB49_04700	COG3279	Response regulator of the LytR AlgR family
BBB49_04705	COG1131	(ABC) transporter
BBB49_04720	COG3655	Transcriptional regulator
BBB49_04745	COG2731	YhcH YjgK YiaL family protein
BBB49_04770	COG0583	DNA-binding transcription factor activity
BBB49_04780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBB49_04785	COG3706	GGDEF domain
BBB49_04795	COG1115	amino acid carrier protein
BBB49_04800	COG1254	Belongs to the acylphosphatase family
BBB49_04805	COG0105	UTP biosynthetic process
BBB49_04815	COG1177	transmembrane transport
BBB49_04820	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBB49_04840	COG1115	amino acid carrier protein
BBB49_04845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBB49_04860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBB49_04870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB49_04875	COG1739	Uncharacterized protein family UPF0029
BBB49_04885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBB49_04895	COG1459	type II secretion system
BBB49_04945	COG0527	aspartate kinase activity
BBB49_04950	COG0004	ammonium transporteR
BBB49_04960	COG0347	Belongs to the P(II) protein family
BBB49_04975	COG0070	glutamate synthase
BBB49_04975	COG0067	glutamate synthase
BBB49_04975	COG0069	glutamate synthase activity
BBB49_04980	COG0493	'glutamate synthase
BBB49_04995	COG0583	DNA-binding transcription factor activity
BBB49_05005	COG0538	isocitrate dehydrogenase activity
BBB49_05020	COG2309	aminopeptidase activity
BBB49_05025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBB49_05025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBB49_05035	COG0741	lytic transglycosylase activity
BBB49_05065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBB49_05065	COG2199	diguanylate cyclase activity
BBB49_05070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBB49_05070	COG0512	Glutamine amidotransferase of anthranilate synthase
BBB49_05075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBB49_05080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBB49_05100	COG5002	protein histidine kinase activity
BBB49_05105	COG5002	protein histidine kinase activity
BBB49_05110	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BBB49_05120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBB49_05125	COG1116	anion transmembrane transporter activity
BBB49_05130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB49_05150	COG1686	Belongs to the peptidase S11 family
BBB49_05160	COG3442	glutamine amidotransferase
BBB49_05165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBB49_05175	COG0826	peptidase U32
BBB49_05180	COG1193	negative regulation of DNA recombination
BBB49_05185	COG1683	Conserved Protein
BBB49_05190	COG0531	amino acid
BBB49_05200	COG0420	3'-5' exonuclease activity
BBB49_05205	COG0419	ATPase involved in DNA repair
BBB49_05210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BBB49_05215	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BBB49_05220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBB49_05230	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BBB49_05235	COG0728	peptidoglycan biosynthetic process
BBB49_05245	COG0438	transferase activity, transferring glycosyl groups
BBB49_05270	COG0012	GTP binding
BBB49_05300	COG0540	Belongs to the ATCase OTCase family
BBB49_05315	COG0284	orotidine-5'-phosphate decarboxylase activity
BBB49_05330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBB49_05335	COG1882	Formate acetyltransferase
BBB49_05370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BBB49_05370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BBB49_05375	COG4632	Exopolysaccharide biosynthesis protein
BBB49_05375	COG5434	Belongs to the glycosyl hydrolase 28 family
BBB49_05385	COG1994	Peptidase M50
BBB49_05390	COG0018	arginyl-trna synthetase
BBB49_05415	COG2333	competence protein COMEC
BBB49_05415	COG0658	competence protein
BBB49_05430	COG2155	Conserved Protein
BBB49_05435	COG1522	sequence-specific DNA binding
BBB49_05465	COG0697	spore germination
BBB49_05470	COG0367	asparagine synthase
BBB49_05485	COG1728	Protein conserved in bacteria
BBB49_05510	COG1132	(ABC) transporter
BBB49_05520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBB49_05525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BBB49_05525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBB49_05540	COG1301	dicarboxylic acid transport
BBB49_05550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB49_05555	COG0765	amino acid transport
BBB49_05560	COG1126	abc transporter atp-binding protein
BBB49_05570	COG0038	chloride channel
BBB49_05575	COG1595	DNA-templated transcription, initiation
BBB49_05585	COG1027	Aspartate ammonia-lyase
BBB49_05595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBB49_05605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBB49_05610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BBB49_05615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBB49_05620	COG0138	bifunctional purine biosynthesis protein purh
BBB49_05625	COG0151	Belongs to the GarS family
BBB49_05635	COG5002	protein histidine kinase activity
BBB49_05640	COG0393	Putative heavy-metal-binding
BBB49_05665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBB49_05675	COG2070	2-Nitropropane dioxygenase
BBB49_05680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBB49_05685	COG1028	Short-chain dehydrogenase reductase Sdr
BBB49_05690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBB49_05695	COG0511	ligase activity, forming carbon-carbon bonds
BBB49_05705	COG0439	Biotin carboxylase
BBB49_05710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBB49_05715	COG0825	malonyl-CoA metabolic process
BBB49_05730	COG4120	Belongs to the binding-protein-dependent transport system permease family
BBB49_05740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BBB49_05745	COG1959	2 iron, 2 sulfur cluster binding
BBB49_05760	COG0482	sulfurtransferase activity
BBB49_05770	COG0628	permease
BBB49_05775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBB49_05780	COG4472	Bacterial protein of unknown function (DUF965)
BBB49_05785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBB49_05795	COG0735	belongs to the Fur family
BBB49_05800	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBB49_05810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBB49_05830	COG1191	sigma factor activity
BBB49_05845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBB49_05855	COG1191	sigma factor activity
BBB49_05860	COG1191	sigma factor activity
BBB49_05865	COG1873	PFAM PRC-barrel domain
BBB49_05870	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBB49_05880	COG0745	RESPONSE REGULATOR receiver
BBB49_05885	COG5002	protein histidine kinase activity
BBB49_05890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BBB49_05895	COG0573	inorganic phosphate transmembrane transporter activity
BBB49_05900	COG0581	inorganic phosphate transmembrane transporter activity
BBB49_05905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBB49_05910	COG0704	Plays a role in the regulation of phosphate uptake
BBB49_05925	COG1160	GTP binding
BBB49_05930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BBB49_05950	COG2252	PERMEase
BBB49_05955	COG1561	YicC-like family, N-terminal region
BBB49_05970	COG1758	RNA polymerase activity
BBB49_05975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBB49_05980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBB49_05990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBB49_05995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBB49_05995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBB49_06000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBB49_06005	COG0631	protein serine/threonine phosphatase activity
BBB49_06015	COG1162	GTPase activity
BBB49_06020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBB49_06030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BBB49_06040	COG1461	Dihydroxyacetone kinase
BBB49_06045	COG1609	Transcriptional regulator
BBB49_06050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBB49_06055	COG0742	ribosomal rna small subunit methyltransferase
BBB49_06060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBB49_06075	COG1323	Belongs to the UPF0348 family
BBB49_06080	COG0280	phosphate acetyltransferase
BBB49_06085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBB49_06095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BBB49_06100	COG0416	fatty acid biosynthetic process
BBB49_06105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBB49_06110	COG0571	ribonuclease III activity
BBB49_06125	COG0552	protein localization to endoplasmic reticulum
BBB49_06130	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BBB49_06135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBB49_06140	COG0228	four-way junction DNA binding
BBB49_06150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBB49_06155	COG0336	Belongs to the RNA methyltransferase TrmD family
BBB49_06160	COG0335	large ribosomal subunit rRNA binding
BBB49_06170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBB49_06180	COG0606	chelatase, subunit chli
BBB49_06185	COG0758	DNA mediated transformation
BBB49_06190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBB49_06195	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBB49_06200	COG0052	Belongs to the universal ribosomal protein uS2 family
BBB49_06210	COG0528	UMP kinase activity
BBB49_06225	COG4589	Belongs to the CDS family
BBB49_06230	COG0628	permease
BBB49_06260	COG0195	Participates in both transcription termination and antitermination
BBB49_06265	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BBB49_06275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBB49_06280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBB49_06295	COG0196	riboflavin kinase activity
BBB49_06300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBB49_06305	COG1185	polyribonucleotide nucleotidyltransferase activity
BBB49_06310	COG0612	Peptidase, M16
BBB49_06320	COG0527	aspartate kinase activity
BBB49_06330	COG0110	maltose O-acetyltransferase activity
BBB49_06335	COG3711	transcriptional antiterminator
BBB49_06340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_06340	COG1263	PTS System
BBB49_06340	COG2190	(PTS) system
BBB49_06350	COG0740	serine-type endopeptidase activity
BBB49_06360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBB49_06365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBB49_06370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBB49_06375	COG1418	mRNA catabolic process
BBB49_06380	COG2359	stage V sporulation protein S
BBB49_06385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBB49_06390	COG2155	Conserved Protein
BBB49_06395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBB49_06420	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBB49_06420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBB49_06425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BBB49_06435	COG1773	rubredoxin
BBB49_06435	COG1592	Rubrerythrin
BBB49_06440	COG2274	protein secretion by the type I secretion system
BBB49_06440	COG3271	cysteine-type peptidase activity
BBB49_06465	COG0348	domain, Protein
BBB49_06480	COG0745	RESPONSE REGULATOR receiver
BBB49_06485	COG2770	Histidine kinase
BBB49_06485	COG2205	protein histidine kinase activity
BBB49_06490	COG2364	Membrane
BBB49_06500	COG0347	Belongs to the P(II) protein family
BBB49_06505	COG1840	ABC-type Fe3 transport system, periplasmic component
BBB49_06510	COG3842	ATPase activity
BBB49_06515	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBB49_06520	COG1177	transmembrane transport
BBB49_06525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BBB49_06550	COG1454	alcohol dehydrogenase
BBB49_06565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB49_06570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB49_06605	COG0534	Mate efflux family protein
BBB49_06615	COG0037	tRNA processing
BBB49_06625	COG0475	glutathione-regulated potassium exporter activity
BBB49_06645	COG4191	Histidine kinase
BBB49_06665	COG1028	Short-chain dehydrogenase reductase Sdr
BBB49_06670	COG5002	protein histidine kinase activity
BBB49_06675	COG0745	RESPONSE REGULATOR receiver
BBB49_06680	COG0612	Peptidase, M16
BBB49_06705	COG5434	Belongs to the glycosyl hydrolase 28 family
BBB49_06705	COG4632	Exopolysaccharide biosynthesis protein
BBB49_06715	COG0534	Mate efflux family protein
BBB49_06735	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBB49_06740	COG1940	carbohydrate kinase activity
BBB49_06745	COG0235	Class ii aldolase
BBB49_06755	COG1619	proteins homologs of microcin C7 resistance protein MccF
BBB49_06760	COG1550	Protein conserved in bacteria
BBB49_06770	COG0861	Integral membrane protein TerC family
BBB49_06800	COG0726	polysaccharide deacetylase
BBB49_06810	COG1523	belongs to the glycosyl hydrolase 13 family
BBB49_06815	COG2171	N-acyltransferase activity
BBB49_06820	COG0436	Aminotransferase
BBB49_06825	COG0601	transmembrane transport
BBB49_06830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB49_06835	COG0444	Belongs to the ABC transporter superfamily
BBB49_06840	COG4608	Belongs to the ABC transporter superfamily
BBB49_06845	COG4166	transmembrane transport
BBB49_06855	COG3608	succinylglutamate desuccinylase aspartoacylase
BBB49_06865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB49_06870	COG0747	negative chemotaxis
BBB49_06875	COG0444	Belongs to the ABC transporter superfamily
BBB49_06880	COG4608	Belongs to the ABC transporter superfamily
BBB49_06890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB49_06900	COG2226	methyltransferase
BBB49_06905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBB49_06910	COG0840	transmembrane signaling receptor activity
BBB49_06920	COG1834	amidinotransferase
BBB49_06925	COG1396	sequence-specific DNA binding
BBB49_06945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BBB49_06955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBB49_06960	COG2201	protein-glutamate methylesterase activity
BBB49_06995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBB49_07000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBB49_07005	COG0569	domain protein
BBB49_07010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBB49_07015	COG2081	HI0933 family
BBB49_07035	COG0726	polysaccharide deacetylase
BBB49_07050	COG1132	(ABC) transporter
BBB49_07060	COG3830	Belongs to the UPF0237 family
BBB49_07065	COG2848	UPF0210 protein
BBB49_07095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBB49_07100	COG0708	Exodeoxyribonuclease III
BBB49_07120	COG1234	tRNA 3'-trailer cleavage
BBB49_07145	COG0840	transmembrane signaling receptor activity
BBB49_07165	COG4753	response regulator
BBB49_07165	COG2207	Transcriptional regulator
BBB49_07170	COG2972	Histidine kinase
BBB49_07180	COG1175	transmembrane transport
BBB49_07185	COG3833	ABC-type maltose transport systems, permease component
BBB49_07200	COG1523	belongs to the glycosyl hydrolase 13 family
BBB49_07220	COG0602	queuosine metabolic process
BBB49_07225	COG0302	gtp cyclohydrolase
BBB49_07230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BBB49_07235	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BBB49_07245	COG1846	Transcriptional regulator
BBB49_07250	COG1132	(ABC) transporter
BBB49_07255	COG1132	(ABC) transporter
BBB49_07280	COG1686	Belongs to the peptidase S11 family
BBB49_07290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBB49_07295	COG3874	Sporulation protein YtfJ
BBB49_07305	COG1686	Belongs to the peptidase S11 family
BBB49_07325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBB49_07330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBB49_07335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBB49_07345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBB49_07350	COG1566	PFAM secretion protein HlyD family protein
BBB49_07355	COG1132	(ABC) transporter
BBB49_07385	COG1193	negative regulation of DNA recombination
BBB49_07400	COG0445	tRNA wobble uridine modification
BBB49_07410	COG2333	competence protein COMEC
BBB49_07410	COG0658	competence protein
BBB49_07420	COG3875	lactate racemase activity
BBB49_07425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BBB49_07430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BBB49_07435	COG4208	sulfate ABC transporter
BBB49_07450	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
BBB49_07455	COG0175	sulfate reduction
BBB49_07460	COG2895	sulfate adenylyltransferase (ATP) activity
BBB49_07485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBB49_07495	COG0778	Nitroreductase
BBB49_07505	COG2086	electron transfer activity
BBB49_07510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBB49_07515	COG1620	l-lactate permease
BBB49_07520	COG0277	FAD linked oxidase domain protein
BBB49_07525	COG1960	acyl-CoA dehydrogenase activity
BBB49_07580	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BBB49_07585	COG0402	S-adenosylhomocysteine deaminase activity
BBB49_07625	COG0210	DNA helicase
BBB49_07655	COG0305	Participates in initiation and elongation during chromosome replication
BBB49_07675	COG3177	Filamentation induced by cAMP protein fic
BBB49_07680	COG1840	ABC-type Fe3 transport system, periplasmic component
BBB49_07685	COG3842	ATPase activity
BBB49_07700	COG2207	Transcriptional regulator
BBB49_07700	COG4753	response regulator
BBB49_07715	COG3328	transposase activity
BBB49_07720	COG0494	nUDIX hydrolase
BBB49_07740	COG1473	amidohydrolase
BBB49_07745	COG0737	Belongs to the 5'-nucleotidase family
BBB49_07760	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BBB49_07765	COG1924	4 iron, 4 sulfur cluster binding
BBB49_07805	COG0406	alpha-ribazole phosphatase activity
BBB49_07810	COG1368	sulfuric ester hydrolase activity
BBB49_07830	COG0561	phosphatase activity
BBB49_07840	COG3706	GGDEF domain
BBB49_07845	COG0667	Aldo Keto reductase
BBB49_07850	COG0531	amino acid
BBB49_07860	COG1725	Transcriptional regulator
BBB49_07865	COG1131	(ABC) transporter
BBB49_07900	COG0668	transmembrane transport
BBB49_07915	COG0531	amino acid
BBB49_07925	COG0561	phosphatase activity
BBB49_07940	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBB49_07950	COG3842	ATPase activity
BBB49_07955	COG0719	Fe-S assembly protein
BBB49_07990	COG0039	L-malate dehydrogenase activity
BBB49_08005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBB49_08010	COG4605	iron ion homeostasis
BBB49_08015	COG4604	ABC transporter, ATP-binding protein
BBB49_08020	COG4607	ABC-type enterochelin transport system periplasmic component
BBB49_08025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBB49_08065	COG2208	phosphoserine phosphatase activity
BBB49_08070	COG2226	methyltransferase
BBB49_08075	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBB49_08080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BBB49_08105	COG0569	domain protein
BBB49_08110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBB49_08115	COG1187	pseudouridine synthase activity
BBB49_08135	COG0768	penicillin binding
BBB49_08165	COG1329	Transcriptional regulator
BBB49_08170	COG1619	proteins homologs of microcin C7 resistance protein MccF
BBB49_08185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBB49_08190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBB49_08210	COG1363	Peptidase, m42
BBB49_08235	COG0523	cobalamin synthesis protein
BBB49_08245	COG0701	Predicted permease
BBB49_08260	COG1028	Short-chain dehydrogenase reductase Sdr
BBB49_08340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB49_08345	COG0765	amino acid transport
BBB49_08360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BBB49_08370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB49_08375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBB49_08390	COG4716	Myosin-crossreactive antigen
BBB49_08405	COG3835	regulator
BBB49_08410	COG2610	gluconate transmembrane transporter activity
BBB49_08415	COG1929	Belongs to the glycerate kinase type-1 family
BBB49_08425	COG1376	ErfK ybiS ycfS ynhG family protein
BBB49_08430	COG2081	HI0933 family
BBB49_08440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBB49_08440	COG0539	negative regulation of cytoplasmic translation
BBB49_08455	COG0523	cobalamin synthesis protein
BBB49_08475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBB49_08480	COG4974	Belongs to the 'phage' integrase family
BBB49_08495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBB49_08500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BBB49_08510	COG1923	regulation of RNA biosynthetic process
BBB49_08515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBB49_08520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBB49_08540	COG2252	PERMEase
BBB49_08555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBB49_08570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BBB49_08585	COG0577	efflux transmembrane transporter activity
BBB49_08590	COG1136	(ABC) transporter
BBB49_08605	COG5002	protein histidine kinase activity
BBB49_08610	COG0534	Mate efflux family protein
BBB49_08615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBB49_08630	COG3584	3D domain protein
BBB49_08630	COG1388	LysM domain
BBB49_08635	COG4399	Belongs to the UPF0754 family
BBB49_08645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBB49_08650	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBB49_08655	COG1285	pathogenesis
BBB49_08660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBB49_08670	COG0488	(ABC) transporter
BBB49_08700	COG0133	tryptophan synthase activity
BBB49_08705	COG0135	phosphoribosylanthranilate isomerase activity
BBB49_08710	COG0134	indole-3-glycerol-phosphate synthase activity
BBB49_08715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBB49_08720	COG0512	Glutamine amidotransferase of anthranilate synthase
BBB49_08720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBB49_08795	COG1141	Ferredoxin
BBB49_08805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBB49_08825	COG1349	DNA-binding transcription factor activity
BBB49_08830	COG0561	phosphatase activity
BBB49_08850	COG0798	PFAM Bile acid sodium symporter
BBB49_08870	COG0640	Transcriptional regulator
BBB49_08880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBB49_08890	COG2201	protein-glutamate methylesterase activity
BBB49_08900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBB49_08910	COG0561	phosphatase activity
BBB49_08930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBB49_08935	COG1879	ABC-type sugar transport system periplasmic component
BBB49_08940	COG1879	ABC-type sugar transport system periplasmic component
BBB49_08950	COG1404	Belongs to the peptidase S8 family
BBB49_08965	COG0494	nUDIX hydrolase
BBB49_08970	COG4708	membrane
BBB49_08990	COG0534	Mate efflux family protein
BBB49_09010	COG1285	pathogenesis
BBB49_09030	COG1533	DNA photolyase activity
BBB49_09035	COG0454	-acetyltransferase
BBB49_09085	COG1216	Glycosyl transferase, family 2
BBB49_09110	COG0657	acetylesterase activity
BBB49_09110	COG2755	lipolytic protein G-D-S-L family
BBB49_09125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBB49_09135	COG3546	catalase activity
BBB49_09165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBB49_09165	COG1199	ATP-dependent helicase activity
BBB49_09205	COG0305	Participates in initiation and elongation during chromosome replication
BBB49_09265	COG5278	phosphoserine phosphatase activity
BBB49_09265	COG0840	transmembrane signaling receptor activity
BBB49_09275	COG1231	oxidoreductase activity
BBB49_09285	COG0662	Cupin 2, conserved barrel domain protein
BBB49_09300	COG1733	regulation of RNA biosynthetic process
BBB49_09315	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BBB49_09320	COG1253	flavin adenine dinucleotide binding
BBB49_09340	COG0693	protein deglycase activity
BBB49_09350	COG1733	regulation of RNA biosynthetic process
BBB49_09380	COG0494	nUDIX hydrolase
BBB49_09430	COG0693	protein deglycase activity
BBB49_09435	COG0488	(ABC) transporter
BBB49_09440	COG0789	Transcriptional regulator
BBB49_09450	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
BBB49_09455	COG0693	protein deglycase activity
BBB49_09545	COG0534	Mate efflux family protein
BBB49_09550	COG0390	transport system, permease component
BBB49_09555	COG4619	ABC transporter
BBB49_09585	COG1725	Transcriptional regulator
BBB49_09595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBB49_09595	COG2080	2 iron, 2 sulfur cluster binding
BBB49_09625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBB49_09625	COG3608	succinylglutamate desuccinylase aspartoacylase
BBB49_09630	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBB49_09630	COG3608	succinylglutamate desuccinylase aspartoacylase
BBB49_09635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBB49_09645	COG1396	sequence-specific DNA binding
BBB49_09650	COG0697	spore germination
BBB49_09655	COG1408	metallophosphoesterase
BBB49_09690	COG1653	transport
BBB49_09725	COG0277	FAD linked oxidase domain protein
BBB49_09730	COG2011	ABC-type metal ion transport system permease component
BBB49_09735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBB49_09745	COG0436	Aminotransferase
BBB49_09750	COG0626	cystathionine gamma-synthase activity
BBB49_09755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBB49_09760	COG0387	Pfam Sodium calcium exchanger
BBB49_09765	COG0464	growth
BBB49_09770	COG0406	alpha-ribazole phosphatase activity
BBB49_09810	COG0436	Aminotransferase
BBB49_09815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBB49_09825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBB49_09850	COG2801	Transposase and inactivated derivatives
BBB49_09855	COG0784	Response regulator, receiver
BBB49_09855	COG0835	chemotaxis
BBB49_09880	COG0745	RESPONSE REGULATOR receiver
BBB49_09885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBB49_09895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBB49_09915	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BBB49_09920	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BBB49_10030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBB49_10030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBB49_10030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBB49_10035	COG1105	Belongs to the carbohydrate kinase PfkB family
BBB49_10040	COG1349	DNA-binding transcription factor activity
BBB49_10055	COG2211	Major facilitator Superfamily
BBB49_10070	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BBB49_10080	COG1028	Short-chain dehydrogenase reductase Sdr
BBB49_10085	COG2721	sulfolactate sulfo-lyase activity
BBB49_10090	COG0246	Mannitol dehydrogenase
BBB49_10095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBB49_10100	COG0800	Aldolase
BBB49_10105	COG1904	glucuronate isomerase
BBB49_10110	COG1609	Transcriptional regulator
BBB49_10115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBB49_10115	COG0646	methionine synthase
BBB49_10125	COG1191	sigma factor activity
BBB49_10135	COG0484	heat shock protein binding
BBB49_10140	COG0514	ATP-dependent DNA helicase (RecQ)
BBB49_10145	COG0765	amino acid transport
BBB49_10150	COG0765	amino acid transport
BBB49_10155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB49_10165	COG0024	Methionine aminopeptidase
BBB49_10190	COG2022	thiamine diphosphate biosynthetic process
BBB49_10200	COG0352	thiamine-phosphate diphosphorylase activity
BBB49_10215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBB49_10220	COG0561	phosphatase activity
BBB49_10225	COG0697	spore germination
BBB49_10240	COG0534	Mate efflux family protein
BBB49_10255	COG0028	Belongs to the TPP enzyme family
BBB49_10260	COG0440	acetolactate synthase activity
BBB49_10265	COG3304	Inner membrane component domain
BBB49_10270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBB49_10275	COG0154	amidase activity
BBB49_10280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBB49_10285	COG0017	Asparaginyl-tRNA synthetase
BBB49_10300	COG0583	DNA-binding transcription factor activity
BBB49_10320	COG0071	Belongs to the small heat shock protein (HSP20) family
BBB49_10340	COG0038	chloride channel
BBB49_10355	COG5002	protein histidine kinase activity
BBB49_10400	COG0785	Cytochrome C biogenesis protein
BBB49_10415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBB49_10420	COG3118	belongs to the thioredoxin family
BBB49_10425	COG0492	ferredoxin-NADP+ reductase activity
BBB49_10435	COG3546	catalase activity
BBB49_10440	COG0494	nUDIX hydrolase
BBB49_10460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBB49_10470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBB49_10480	COG0840	transmembrane signaling receptor activity
BBB49_10480	COG5278	phosphoserine phosphatase activity
BBB49_10495	COG4974	Belongs to the 'phage' integrase family
BBB49_10515	COG0411	ABC transporter
BBB49_10525	COG0559	Belongs to the binding-protein-dependent transport system permease family
BBB49_10535	COG1011	Hydrolase
BBB49_10540	COG0745	RESPONSE REGULATOR receiver
BBB49_10570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BBB49_10595	COG0745	RESPONSE REGULATOR receiver
BBB49_10600	COG0750	zinc metalloprotease
BBB49_10605	COG0497	DNA recombination
BBB49_10610	COG1438	arginine binding
BBB49_10615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBB49_10620	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBB49_10625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBB49_10630	COG0142	geranyltranstransferase activity
BBB49_10635	COG1722	exodeoxyribonuclease VII activity
BBB49_10640	COG1570	exodeoxyribonuclease VII activity
BBB49_10650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBB49_10655	COG1302	Protein conserved in bacteria
BBB49_10695	COG3854	ATPases associated with a variety of cellular activities
BBB49_10770	COG1737	Transcriptional regulator
BBB49_10775	COG0116	Belongs to the methyltransferase superfamily
BBB49_10785	COG0564	pseudouridine synthase activity
BBB49_10805	COG1799	cell septum assembly
BBB49_10810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBB49_10820	COG3856	small basic protein
BBB49_10840	COG0772	Belongs to the SEDS family
BBB49_10845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBB49_10850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBB49_10860	COG0768	penicillin binding
BBB49_10865	COG0768	penicillin binding
BBB49_10875	COG0275	rRNA processing
BBB49_10880	COG2001	Belongs to the MraZ family
BBB49_10905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BBB49_10920	COG1522	sequence-specific DNA binding
BBB49_10935	COG0671	phosphoesterase, PA-phosphatase related
BBB49_10945	COG2703	oxygen carrier activity
BBB49_10950	COG1966	Carbon starvation protein
BBB49_10965	COG0432	Pfam Uncharacterised protein family UPF0047
BBB49_10975	COG1012	belongs to the aldehyde dehydrogenase family
BBB49_10985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BBB49_11000	COG0534	Mate efflux family protein
BBB49_11020	COG0840	transmembrane signaling receptor activity
BBB49_11045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBB49_11045	COG0425	Belongs to the sulfur carrier protein TusA family
BBB49_11050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBB49_11055	COG2966	Psort location CytoplasmicMembrane, score
BBB49_11085	COG0628	permease
BBB49_11100	COG1187	pseudouridine synthase activity
BBB49_11130	COG0488	(ABC) transporter
BBB49_11140	COG1187	pseudouridine synthase activity
BBB49_11145	COG0840	transmembrane signaling receptor activity
BBB49_11160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBB49_11170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBB49_11175	COG0628	permease
BBB49_11180	COG0572	uridine kinase
BBB49_11190	COG1307	EDD domain protein, DegV family
BBB49_11210	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBB49_11220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BBB49_11225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBB49_11230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BBB49_11235	COG4670	ketone body catabolic process
BBB49_11245	COG0584	glycerophosphoryl diester phosphodiesterase
BBB49_11250	COG0840	transmembrane signaling receptor activity
BBB49_11260	COG0460	homoserine dehydrogenase
BBB49_11270	COG1316	TRANSCRIPTIONal
BBB49_11280	COG0367	asparagine synthase
BBB49_11285	COG4464	protein tyrosine phosphatase activity
BBB49_11290	COG0489	protein tyrosine kinase activity
BBB49_11300	COG1132	(ABC) transporter
BBB49_11325	COG2244	polysaccharide biosynthetic process
BBB49_11330	COG1442	glycosyl transferase family 8
BBB49_11330	COG1216	Glycosyl transferase, family 2
BBB49_11340	COG1091	dTDP-4-dehydrorhamnose reductase activity
BBB49_11355	COG1216	Glycosyl transferase, family 2
BBB49_11355	COG1442	glycosyl transferase family 8
BBB49_11375	COG0438	transferase activity, transferring glycosyl groups
BBB49_11375	COG0297	glycogen (starch) synthase activity
BBB49_11380	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BBB49_11390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BBB49_11395	COG3944	biosynthesis protein
BBB49_11405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBB49_11415	COG1811	Na channel or pump
BBB49_11420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBB49_11425	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBB49_11440	COG1763	Mo-molybdopterin cofactor biosynthetic process
BBB49_11450	COG0303	'Molybdopterin
BBB49_11470	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBB49_11480	COG0243	molybdopterin cofactor binding
BBB49_11485	COG2221	Nitrite and sulphite reductase 4Fe-4S
BBB49_11510	COG2199	diguanylate cyclase activity
BBB49_11510	COG2203	Gaf domain
BBB49_11515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBB49_11520	COG0124	histidyl-tRNA synthetase
BBB49_11525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBB49_11530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBB49_11535	COG1490	D-aminoacyl-tRNA deacylase activity
BBB49_11540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBB49_11545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBB49_11550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBB49_11550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBB49_11555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBB49_11560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBB49_11570	COG1862	Preprotein translocase
BBB49_11575	COG0343	queuine tRNA-ribosyltransferase activity
BBB49_11580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBB49_11585	COG2255	four-way junction helicase activity
BBB49_11590	COG0632	four-way junction helicase activity
BBB49_11670	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BBB49_11690	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBB49_11870	COG2002	toxin-antitoxin pair type II binding
BBB49_11875	COG1484	DNA-dependent DNA replication
BBB49_11900	COG0582	viral genome integration into host DNA
BBB49_11945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BBB49_11955	COG0647	UMP catabolic process
BBB49_11960	COG0366	Alpha amylase catalytic
BBB49_11965	COG3833	ABC-type maltose transport systems, permease component
BBB49_11970	COG1175	transmembrane transport
BBB49_11975	COG2182	Extracellular solute-binding protein
BBB49_11980	COG1917	Cupin 2, conserved barrel domain protein
BBB49_11980	COG2207	Transcriptional regulator
BBB49_11985	COG0577	efflux transmembrane transporter activity
BBB49_11990	COG1136	(ABC) transporter
BBB49_12005	COG0745	RESPONSE REGULATOR receiver
BBB49_12015	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BBB49_12020	COG1773	rubredoxin
BBB49_12020	COG1592	Rubrerythrin
BBB49_12030	COG0484	heat shock protein binding
BBB49_12050	COG0613	PHP domain protein
BBB49_12055	COG1362	aminopeptidase activity
BBB49_12060	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBB49_12100	COG0646	methionine synthase
BBB49_12100	COG1410	methionine synthase
BBB49_12110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBB49_12150	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBB49_12155	COG1269	ATP hydrolysis coupled proton transport
BBB49_12180	COG2244	polysaccharide biosynthetic process
BBB49_12185	COG2723	6-phospho-beta-galactosidase activity
BBB49_12190	COG1263	PTS System
BBB49_12190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_12190	COG2190	(PTS) system
BBB49_12195	COG3711	transcriptional antiterminator
BBB49_12205	COG0564	pseudouridine synthase activity
BBB49_12215	COG0849	cell division
BBB49_12235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BBB49_12250	COG0735	belongs to the Fur family
BBB49_12280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BBB49_12285	COG0470	DNA polymerase III
BBB49_12285	COG1067	ATP-dependent peptidase activity
BBB49_12290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBB49_12300	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBB49_12315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BBB49_12320	COG0140	phosphoribosyl-ATP diphosphatase activity
BBB49_12325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBB49_12330	COG0107	imidazoleglycerol-phosphate synthase activity
BBB49_12335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBB49_12340	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBB49_12345	COG0131	Imidazoleglycerol-phosphate dehydratase
BBB49_12350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBB49_12355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBB49_12385	COG2084	Dehydrogenase
BBB49_12410	COG4492	Belongs to the UPF0735 family
BBB49_12415	COG0083	homoserine kinase activity
BBB49_12420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBB49_12440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BBB49_12455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBB49_12460	COG0113	porphobilinogen synthase activity
BBB49_12465	COG1587	Uroporphyrinogen-III synthase
BBB49_12465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BBB49_12480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BBB49_12485	COG2221	Nitrite and sulphite reductase 4Fe-4S
BBB49_12490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBB49_12500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBB49_12505	COG3326	Membrane
BBB49_12510	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BBB49_12515	COG2706	6-phosphogluconolactonase activity
BBB49_12520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBB49_12530	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBB49_12535	COG0561	phosphatase activity
BBB49_12555	COG1492	cobalamin metabolic process
BBB49_12560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBB49_12585	COG2875	Belongs to the precorrin methyltransferase family
BBB49_12605	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BBB49_12615	COG1797	cobyrinic acid a,c-diamide synthase activity
BBB49_12625	COG3263	regulation of cellular component size
BBB49_12635	COG0840	transmembrane signaling receptor activity
BBB49_12650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BBB49_12655	COG1802	Transcriptional regulator
BBB49_12670	COG0813	purine-nucleoside phosphorylase activity
BBB49_12675	COG3958	Transketolase
BBB49_12680	COG3959	Transketolase, thiamine diphosphate binding domain
BBB49_12695	COG0295	cytidine deaminase activity
BBB49_12700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BBB49_12705	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BBB49_12720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBB49_12730	COG3958	Transketolase
BBB49_12735	COG3959	Transketolase, thiamine diphosphate binding domain
BBB49_12745	COG0235	Class ii aldolase
BBB49_12760	COG3037	sugar-specific permease SgaT UlaA
BBB49_12775	COG1349	DNA-binding transcription factor activity
BBB49_12780	COG0733	neurotransmitter:sodium symporter activity
BBB49_12810	COG1476	TRANSCRIPTIONal
BBB49_12830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BBB49_12835	COG4521	taurine ABC transporter
BBB49_12840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB49_12845	COG2801	Transposase and inactivated derivatives
BBB49_12850	COG2508	Transcriptional regulator
BBB49_12865	COG2200	EAL domain
BBB49_12870	COG0110	maltose O-acetyltransferase activity
BBB49_12875	COG0366	Alpha amylase catalytic
BBB49_12880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BBB49_12895	COG2059	Chromate
BBB49_12930	COG2207	Transcriptional regulator
BBB49_12945	COG4753	response regulator
BBB49_12945	COG2207	Transcriptional regulator
BBB49_12950	COG2972	Histidine kinase
BBB49_12955	COG3290	protein histidine kinase activity
BBB49_12955	COG0840	transmembrane signaling receptor activity
BBB49_12960	COG1874	Beta-galactosidase
BBB49_12980	COG1609	Transcriptional regulator
BBB49_13015	COG1982	Orn Lys Arg decarboxylase major
BBB49_13030	COG1785	Belongs to the alkaline phosphatase family
BBB49_13040	COG1940	carbohydrate kinase activity
BBB49_13075	COG0395	ABC-type sugar transport system, permease component
BBB49_13095	COG2207	Transcriptional regulator
BBB49_13100	COG0366	Alpha amylase catalytic
BBB49_13105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBB49_13110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBB49_13115	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BBB49_13135	COG0366	Alpha amylase catalytic
BBB49_13140	COG1307	EDD domain protein, DegV family
BBB49_13155	COG2972	Histidine kinase
BBB49_13160	COG2207	Transcriptional regulator
BBB49_13160	COG4753	response regulator
BBB49_13165	COG0840	transmembrane signaling receptor activity
BBB49_13170	COG4214	carbohydrate transport
BBB49_13180	COG4213	ABC transporter substrate-binding protein
BBB49_13195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBB49_13215	COG2160	L-arabinose isomerase activity
BBB49_13220	COG2017	converts alpha-aldose to the beta-anomer
BBB49_13225	COG0561	phosphatase activity
BBB49_13240	COG0613	PHP domain protein
BBB49_13245	COG0514	ATP-dependent DNA helicase (RecQ)
BBB49_13255	COG0352	thiamine-phosphate diphosphorylase activity
BBB49_13260	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BBB49_13270	COG0351	phosphomethylpyrimidine kinase
BBB49_13285	COG2814	Major facilitator Superfamily
BBB49_13290	COG1378	Sugar-specific transcriptional regulator TrmB
BBB49_13305	COG0488	(ABC) transporter
BBB49_13325	COG0569	domain protein
BBB49_13330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBB49_13340	COG1122	ATPase activity
BBB49_13365	COG0830	nickel cation binding
BBB49_13370	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BBB49_13375	COG0804	urea catabolic process
BBB49_13385	COG0831	urea catabolic process
BBB49_13400	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BBB49_13410	COG1454	alcohol dehydrogenase
BBB49_13415	COG1116	anion transmembrane transporter activity
BBB49_13420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB49_13425	COG0347	Belongs to the P(II) protein family
BBB49_13430	COG0347	Belongs to the P(II) protein family
BBB49_13435	COG2508	Transcriptional regulator
BBB49_13445	COG0010	Belongs to the arginase family
BBB49_13455	COG0347	Belongs to the P(II) protein family
BBB49_13475	COG0559	Belongs to the binding-protein-dependent transport system permease family
BBB49_13485	COG4753	response regulator
BBB49_13485	COG2207	Transcriptional regulator
BBB49_13490	COG0784	Response regulator, receiver
BBB49_13490	COG2198	Histidine kinase
BBB49_13490	COG5002	protein histidine kinase activity
BBB49_13495	COG4251	negative regulation of phosphorylation
BBB49_13500	COG1760	l-serine dehydratase
BBB49_13510	COG1263	PTS System
BBB49_13510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_13515	COG3711	transcriptional antiterminator
BBB49_13520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBB49_13525	COG2323	membrane
BBB49_13535	COG0137	argininosuccinate synthase activity
BBB49_13540	COG0165	Argininosuccinate lyase
BBB49_13545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BBB49_13555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BBB49_13560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BBB49_13565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBB49_13570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBB49_13575	COG1268	BioY protein
BBB49_13605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBB49_13615	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BBB49_13620	COG2188	Transcriptional regulator
BBB49_13625	COG1482	cell wall glycoprotein biosynthetic process
BBB49_13630	COG2723	6-phospho-beta-galactosidase activity
BBB49_13655	COG0840	transmembrane signaling receptor activity
BBB49_13660	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BBB49_13665	COG0395	ABC-type sugar transport system, permease component
BBB49_13685	COG3842	ATPase activity
BBB49_13695	COG2207	Transcriptional regulator
BBB49_13695	COG4753	response regulator
BBB49_13700	COG2972	Histidine kinase
BBB49_13705	COG3328	transposase activity
BBB49_13730	COG1940	carbohydrate kinase activity
BBB49_13735	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BBB49_13745	COG3458	cephalosporin-C deacetylase activity
BBB49_13750	COG1053	succinate dehydrogenase
BBB49_13755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB49_13760	COG4608	Belongs to the ABC transporter superfamily
BBB49_13765	COG0444	Belongs to the ABC transporter superfamily
BBB49_13770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB49_13775	COG0601	transmembrane transport
BBB49_13785	COG2801	Transposase and inactivated derivatives
BBB49_13790	COG1737	Transcriptional regulator
BBB49_13800	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBB49_13810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBB49_13825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBB49_13830	COG2271	Major facilitator Superfamily
BBB49_13835	COG0662	Cupin 2, conserved barrel domain protein
BBB49_13835	COG2207	Transcriptional regulator
BBB49_13845	COG0583	DNA-binding transcription factor activity
BBB49_13855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBB49_13860	COG1605	Chorismate mutase
BBB49_13860	COG0077	Prephenate dehydratase
BBB49_13865	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BBB49_13870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BBB49_13875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBB49_13880	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBB49_13900	COG0495	leucyl-tRNA aminoacylation
BBB49_13915	COG1131	(ABC) transporter
BBB49_13920	COG0717	Belongs to the dCTP deaminase family
BBB49_13955	COG2357	RelA SpoT domain protein
BBB49_13965	COG3290	protein histidine kinase activity
BBB49_13965	COG0840	transmembrane signaling receptor activity
BBB49_13985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBB49_13995	COG2199	diguanylate cyclase activity
BBB49_13995	COG2203	Gaf domain
BBB49_14000	COG0438	transferase activity, transferring glycosyl groups
BBB49_14010	COG3344	reverse transcriptase
BBB49_14015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBB49_14020	COG5002	protein histidine kinase activity
BBB49_14025	COG0745	RESPONSE REGULATOR receiver
BBB49_14035	COG1136	(ABC) transporter
BBB49_14035	COG0577	efflux transmembrane transporter activity
BBB49_14040	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BBB49_14045	COG1131	(ABC) transporter
BBB49_14050	COG1773	rubredoxin
BBB49_14050	COG1592	Rubrerythrin
BBB49_14055	COG1114	Component of the transport system for branched-chain amino acids
BBB49_14065	COG3328	transposase activity
BBB49_14070	COG0840	transmembrane signaling receptor activity
BBB49_14075	COG0561	phosphatase activity
BBB49_14080	COG2723	6-phospho-beta-galactosidase activity
BBB49_14085	COG1486	melibiose metabolic process
BBB49_14090	COG0697	spore germination
BBB49_14095	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BBB49_14100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB49_14105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBB49_14125	COG0366	Alpha amylase catalytic
BBB49_14155	COG4750	Nucleotidyl transferase
BBB49_14180	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBB49_14185	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBB49_14185	COG2247	cell wall binding repeat
BBB49_14190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBB49_14260	COG0577	efflux transmembrane transporter activity
BBB49_14260	COG1136	(ABC) transporter
BBB49_14270	COG0840	transmembrane signaling receptor activity
BBB49_14280	COG0747	negative chemotaxis
BBB49_14295	COG0444	Belongs to the ABC transporter superfamily
BBB49_14300	COG4608	Belongs to the ABC transporter superfamily
BBB49_14315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBB49_14330	COG2244	polysaccharide biosynthetic process
BBB49_14345	COG1216	Glycosyl transferase, family 2
BBB49_14350	COG1442	glycosyl transferase family 8
BBB49_14350	COG1216	Glycosyl transferase, family 2
BBB49_14360	COG1215	transferase activity, transferring glycosyl groups
BBB49_14380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBB49_14390	COG0489	protein tyrosine kinase activity
BBB49_14395	COG3944	biosynthesis protein
BBB49_14410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBB49_14500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BBB49_14510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBB49_14530	COG1682	transport, permease protein
BBB49_14540	COG1091	dTDP-4-dehydrorhamnose reductase activity
BBB49_14645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBB49_14650	COG5002	protein histidine kinase activity
BBB49_14655	COG2199	diguanylate cyclase activity
BBB49_14655	COG2200	EAL domain
BBB49_14655	COG2202	Pas domain
BBB49_14660	COG4974	Belongs to the 'phage' integrase family
BBB49_14665	COG3459	Glycosyltransferase 36 associated
BBB49_14680	COG1362	aminopeptidase activity
BBB49_14690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBB49_14690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBB49_14695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBB49_14700	COG1418	mRNA catabolic process
BBB49_14705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB49_14715	COG3590	peptidase
BBB49_14720	COG1126	abc transporter atp-binding protein
BBB49_14725	COG0765	amino acid transport
BBB49_14730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB49_14735	COG3973	AAA domain
BBB49_14740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBB49_14765	COG0019	diaminopimelate decarboxylase activity
BBB49_14785	COG0840	transmembrane signaling receptor activity
BBB49_14800	COG2608	mercury ion transmembrane transporter activity
BBB49_14810	COG1937	Protein conserved in bacteria
BBB49_14820	COG3279	Response regulator of the LytR AlgR family
BBB49_14845	COG1811	Na channel or pump
BBB49_14850	COG0789	Transcriptional regulator
BBB49_14850	COG4978	Transcriptional regulator
BBB49_14865	COG2832	Protein of unknown function (DUF454)
BBB49_14875	COG1132	(ABC) transporter
BBB49_14880	COG4988	ABC transporter
BBB49_14885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBB49_14895	COG0745	RESPONSE REGULATOR receiver
BBB49_14900	COG2205	protein histidine kinase activity
BBB49_14905	COG0569	domain protein
BBB49_14910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBB49_14945	COG1404	Belongs to the peptidase S8 family
BBB49_14970	COG0469	pyruvate kinase activity
BBB49_15015	COG1481	regulation of sporulation
BBB49_15020	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BBB49_15025	COG1660	Displays ATPase and GTPase activities
BBB49_15030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBB49_15035	COG0322	excinuclease ABC activity
BBB49_15040	COG0768	penicillin binding
BBB49_15060	COG0556	nucleotide-excision repair
BBB49_15070	COG3409	Peptidoglycan-binding domain 1 protein
BBB49_15070	COG0793	Belongs to the peptidase S41A family
BBB49_15075	COG2177	Part of the ABC transporter FtsEX involved in
BBB49_15080	COG2884	Cell division ATP-binding protein ftsE
BBB49_15085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBB49_15090	COG3958	Transketolase
BBB49_15095	COG3959	Transketolase, thiamine diphosphate binding domain
BBB49_15100	COG2337	Toxic component of a toxin-antitoxin (TA) module
BBB49_15115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBB49_15115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBB49_15120	COG0736	holo-[acyl-carrier-protein] synthase activity
BBB49_15135	COG1295	ribonuclease BN
BBB49_15140	COG1696	Membrane protein involved in D-alanine export
BBB49_15165	COG1199	ATP-dependent helicase activity
BBB49_15175	COG2002	toxin-antitoxin pair type II binding
BBB49_15185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBB49_15200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBB49_15205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBB49_15210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BBB49_15240	COG2378	regulation of single-species biofilm formation
BBB49_15245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBB49_15260	COG2357	RelA SpoT domain protein
BBB49_15275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBB49_15295	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BBB49_15350	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBB49_15405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBB49_15410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBB49_15420	COG0297	glycogen (starch) synthase activity
BBB49_15460	COG2190	(PTS) system
BBB49_15465	COG1263	PTS System
BBB49_15465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_15465	COG2190	(PTS) system
BBB49_15470	COG3711	transcriptional antiterminator
BBB49_15475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBB49_15480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BBB49_15485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBB49_15495	COG4608	Belongs to the ABC transporter superfamily
BBB49_15500	COG0444	Belongs to the ABC transporter superfamily
BBB49_15510	COG0601	transmembrane transport
BBB49_15525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBB49_15530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BBB49_15565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBB49_15575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BBB49_15580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBB49_15585	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBB49_15595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB49_15600	COG1126	abc transporter atp-binding protein
BBB49_15605	COG0765	amino acid transport
BBB49_15610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB49_15615	COG0252	asparaginase activity
BBB49_15625	COG1454	alcohol dehydrogenase
BBB49_15630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBB49_15720	COG0590	tRNA wobble adenosine to inosine editing
BBB49_15725	COG4536	flavin adenine dinucleotide binding
BBB49_15735	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBB49_15770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBB49_15775	COG1621	beta-fructofuranosidase activity
BBB49_15780	COG1609	Transcriptional regulator
BBB49_15795	COG3620	sequence-specific DNA binding
BBB49_15800	COG1492	cobalamin metabolic process
BBB49_15810	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BBB49_15815	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BBB49_15850	COG3716	PTS system mannose fructose sorbose family IID component
BBB49_15855	COG3715	PTS system
BBB49_15860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_15865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BBB49_15875	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BBB49_15890	COG3590	peptidase
BBB49_15895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBB49_15905	COG0513	Belongs to the DEAD box helicase family
BBB49_15915	COG1360	Flagellar Motor Protein
BBB49_15920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BBB49_15925	COG2801	Transposase and inactivated derivatives
BBB49_15930	COG0617	tRNA 3'-terminal CCA addition
BBB49_15935	COG1115	amino acid carrier protein
BBB49_15940	COG0347	Belongs to the P(II) protein family
BBB49_15945	COG0004	ammonium transporteR
BBB49_15955	COG0659	secondary active sulfate transmembrane transporter activity
BBB49_15960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB49_15965	COG0730	response to heat
BBB49_16020	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BBB49_16025	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BBB49_16030	COG2723	6-phospho-beta-galactosidase activity
BBB49_16035	COG2188	Transcriptional regulator
BBB49_16040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBB49_16050	COG1447	Phosphotransferase system cellobiose-specific component IIA
BBB49_16075	COG2824	Alkylphosphonate utilization operon protein PhnA
BBB49_16080	COG0306	phosphate transporter
BBB49_16085	COG1392	Phosphate transport regulator
BBB49_16100	COG0653	protein targeting
BBB49_16105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBB49_16135	COG1404	Belongs to the peptidase S8 family
BBB49_16145	COG1484	DNA-dependent DNA replication
BBB49_16210	COG2081	HI0933 family
BBB49_16220	COG0385	Bile acid
BBB49_16235	COG0281	malic enzyme
BBB49_16250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBB49_16260	COG0305	Participates in initiation and elongation during chromosome replication
BBB49_16265	COG1067	ATP-dependent peptidase activity
BBB49_16265	COG0470	DNA polymerase III
BBB49_16270	COG0359	binds to the 23S rRNA
BBB49_16275	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BBB49_16285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBB49_16295	COG0360	Binds together with S18 to 16S ribosomal RNA
BBB49_16305	COG0668	transmembrane transport
BBB49_16320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBB49_16330	COG2801	Transposase and inactivated derivatives
BBB49_16340	COG1475	DNA binding
BBB49_16345	COG1192	Involved in chromosome partitioning
BBB49_16350	COG1475	DNA binding
BBB49_16360	COG0445	tRNA wobble uridine modification
BBB49_16365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBB49_16370	COG1847	R3H domain protein
BBB49_16380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBB49_16385	COG0594	ribonuclease P activity
BBB49_16390	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BBB49_16400	COG5002	protein histidine kinase activity
BBB49_16410	COG1122	ATPase activity
BBB49_16415	COG0310	cobalt ion transport
BBB49_16425	COG0386	Belongs to the glutathione peroxidase family
BBB49_16430	COG0386	Belongs to the glutathione peroxidase family
BBB49_16450	COG0671	phosphoesterase, PA-phosphatase related
BBB49_16455	COG0583	DNA-binding transcription factor activity
BBB49_16475	COG2076	Multidrug Resistance protein
BBB49_16485	COG2033	superoxide reductase activity
BBB49_16495	COG0701	Predicted permease
BBB49_16505	COG1854	S-ribosylhomocysteine lyase activity
BBB49_16515	COG1546	Belongs to the CinA family
BBB49_16515	COG1058	Belongs to the CinA family
BBB49_16525	COG4974	Belongs to the 'phage' integrase family
BBB49_16535	COG1192	Involved in chromosome partitioning
BBB49_16555	COG0786	glutamate:sodium symporter activity
BBB49_16565	COG1357	PFAM Pentapeptide repeats (8 copies)
BBB49_16585	COG1122	ATPase activity
BBB49_16610	COG3158	transport of potassium into the cell
BBB49_16615	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BBB49_16620	COG0667	Aldo Keto reductase
BBB49_16630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBB49_16635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBB49_16640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBB49_16645	COG1120	ATPase activity
BBB49_16655	COG4978	Transcriptional regulator
BBB49_16655	COG0789	Transcriptional regulator
BBB49_16660	COG1132	(ABC) transporter
BBB49_16665	COG1132	(ABC) transporter
BBB49_16680	COG2233	PERMEase
BBB49_16685	COG0277	FAD linked oxidase domain protein
BBB49_16690	COG1028	Short-chain dehydrogenase reductase Sdr
BBB49_16695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBB49_16700	COG1737	Transcriptional regulator
BBB49_16700	COG0837	glucose binding
BBB49_16705	COG2197	response regulator
BBB49_16745	COG3715	PTS system
BBB49_16750	COG3716	PTS system mannose fructose sorbose family IID component
BBB49_16760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BBB49_16770	COG3850	Histidine kinase
BBB49_16770	COG5002	protein histidine kinase activity
BBB49_16775	COG0697	spore germination
BBB49_16780	COG0840	transmembrane signaling receptor activity
BBB49_16815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBB49_16820	COG1879	ABC-type sugar transport system periplasmic component
BBB49_16830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBB49_16835	COG1609	Transcriptional regulator
BBB49_16845	COG1328	CTP reductase activity
BBB49_16855	COG5002	protein histidine kinase activity
BBB49_16860	COG1342	Belongs to the UPF0251 family
BBB49_16875	COG4555	ABC transporter
BBB49_16890	COG1966	Carbon starvation protein
BBB49_16905	COG1216	Glycosyl transferase, family 2
BBB49_16910	COG2207	Transcriptional regulator
BBB49_16915	COG1132	(ABC) transporter
BBB49_16920	COG1132	(ABC) transporter
BBB49_16945	COG0583	DNA-binding transcription factor activity
BBB49_16985	COG0148	phosphopyruvate hydratase activity
BBB49_17000	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BBB49_17005	COG4149	molybdate abc transporter
BBB49_17010	COG0725	ABC transporter, periplasmic molybdate-binding protein
BBB49_17025	COG1910	domain protein
BBB49_17040	COG0347	Belongs to the P(II) protein family
BBB49_17060	COG1433	Dinitrogenase iron-molybdenum cofactor
BBB49_17060	COG0535	radical SAM domain protein
BBB49_17065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBB49_17090	COG1609	Transcriptional regulator
BBB49_17090	COG2207	Transcriptional regulator
BBB49_17110	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BBB49_17115	COG3275	phosphorelay sensor kinase activity
BBB49_17120	COG2207	Transcriptional regulator
BBB49_17140	COG0450	alkyl hydroperoxide reductase
BBB49_17155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BBB49_17230	COG1349	DNA-binding transcription factor activity
BBB49_17235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBB49_17250	COG1737	Transcriptional regulator
BBB49_17255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBB49_17255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBB49_17255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBB49_17260	COG0383	alpha-mannosidase activity
BBB49_17265	COG1917	Cupin 2, conserved barrel domain protein
BBB49_17265	COG2207	Transcriptional regulator
BBB49_17300	COG2190	(PTS) system
BBB49_17300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_17300	COG1263	PTS System
BBB49_17320	COG3507	Belongs to the glycosyl hydrolase 43 family
BBB49_17330	COG2116	formate transmembrane transporter activity
BBB49_17335	COG1882	Formate acetyltransferase
BBB49_17340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBB49_17350	COG1131	(ABC) transporter
BBB49_17370	COG0789	Transcriptional regulator
BBB49_17380	COG0583	DNA-binding transcription factor activity
BBB49_17385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBB49_17395	COG3842	ATPase activity
BBB49_17400	COG1175	transmembrane transport
BBB49_17405	COG0395	ABC-type sugar transport system, permease component
BBB49_17415	COG5566	PFAM Mor transcription activator
BBB49_17435	COG0561	phosphatase activity
BBB49_17445	COG2239	Acts as a magnesium transporter
BBB49_17485	COG0784	Response regulator, receiver
BBB49_17485	COG3437	response regulator, receiver
BBB49_17490	COG1247	-acetyltransferase
BBB49_17505	COG0583	DNA-binding transcription factor activity
BBB49_17510	COG0747	negative chemotaxis
BBB49_17515	COG0601	transmembrane transport
BBB49_17540	COG0534	Mate efflux family protein
BBB49_17550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_17550	COG1263	PTS System
BBB49_17560	COG2136	Putative SAM-dependent methyltransferase
BBB49_17560	COG2521	methyltransferase
BBB49_17590	COG2226	methyltransferase
BBB49_17595	COG1609	Transcriptional regulator
BBB49_17600	COG0534	Mate efflux family protein
BBB49_17605	COG2746	aminoglycoside 3-N-acetyltransferase activity
BBB49_17615	COG1346	cytolysis
BBB49_17625	COG2186	Transcriptional regulator
BBB49_17630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBB49_17640	COG1116	anion transmembrane transporter activity
BBB49_17650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB49_17655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBB49_17665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BBB49_17665	COG0167	dihydroorotate dehydrogenase activity
BBB49_17675	COG0133	tryptophan synthase activity
BBB49_17680	COG0159	tryptophan synthase activity
BBB49_17685	COG0583	DNA-binding transcription factor activity
BBB49_17710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBB49_17720	COG1737	Transcriptional regulator
BBB49_17725	COG0363	glucosamine-6-phosphate deaminase activity
BBB49_17735	COG5002	protein histidine kinase activity
BBB49_17750	COG0515	serine threonine protein kinase
BBB49_17760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_17760	COG1263	PTS System
BBB49_17765	COG0366	Alpha amylase catalytic
BBB49_17770	COG2188	Transcriptional regulator
BBB49_17775	COG0426	domain, Protein
BBB49_17780	COG0586	Pfam SNARE associated Golgi protein
BBB49_17790	COG3328	transposase activity
BBB49_17810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBB49_17820	COG3706	GGDEF domain
BBB49_17830	COG1028	Short-chain dehydrogenase reductase Sdr
BBB49_17850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BBB49_17855	COG0789	Transcriptional regulator
BBB49_17905	COG1132	(ABC) transporter
BBB49_17910	COG1132	(ABC) transporter
BBB49_17945	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBB49_17950	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBB49_17960	COG2801	Transposase and inactivated derivatives
BBB49_17965	COG2508	Transcriptional regulator
BBB49_17975	COG3257	ureidoglycine aminohydrolase activity
BBB49_17980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBB49_18000	COG4974	Belongs to the 'phage' integrase family
BBB49_18010	COG0346	lactoylglutathione lyase activity
BBB49_18025	COG3853	Toxic anion resistance protein (TelA)
BBB49_18035	COG0534	Mate efflux family protein
BBB49_18045	COG1151	hydroxylamine reductase activity
BBB49_18055	COG1335	isochorismatase
BBB49_18065	COG1733	regulation of RNA biosynthetic process
BBB49_18080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBB49_18090	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BBB49_18110	COG5002	protein histidine kinase activity
BBB49_18120	COG3963	phosphatidate phosphatase activity
BBB49_18130	COG4989	oxidoreductase activity
BBB49_18135	COG1737	Transcriptional regulator
BBB49_18150	COG2971	BadF BadG BcrA BcrD
BBB49_18165	COG1447	Phosphotransferase system cellobiose-specific component IIA
BBB49_18170	COG1486	melibiose metabolic process
BBB49_18175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBB49_18180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBB49_18200	COG0789	Transcriptional regulator
BBB49_18235	COG1408	metallophosphoesterase
BBB49_18255	COG2264	protein methyltransferase activity
BBB49_18260	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BBB49_18265	COG0371	Dehydrogenase
BBB49_18275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBB49_18280	COG0583	DNA-binding transcription factor activity
BBB49_18285	COG0697	spore germination
BBB49_18310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BBB49_18315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBB49_18325	COG0840	transmembrane signaling receptor activity
BBB49_18350	COG0656	L-ascorbic acid biosynthetic process
BBB49_18385	COG0534	Mate efflux family protein
BBB49_18395	COG0586	Pfam SNARE associated Golgi protein
BBB49_18440	COG0640	Transcriptional regulator
BBB49_18445	COG1307	EDD domain protein, DegV family
BBB49_18450	COG1309	transcriptional regulator
BBB49_18455	COG0561	phosphatase activity
BBB49_18465	COG3716	PTS system mannose fructose sorbose family IID component
BBB49_18490	COG2197	response regulator
BBB49_18495	COG4585	Histidine kinase
BBB49_18515	COG0840	transmembrane signaling receptor activity
BBB49_18520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB49_18525	COG1126	abc transporter atp-binding protein
BBB49_18530	COG0765	amino acid transport
BBB49_18540	COG0778	Nitroreductase
BBB49_18545	COG1301	dicarboxylic acid transport
BBB49_18550	COG1910	domain protein
BBB49_18555	COG0725	ABC transporter, periplasmic molybdate-binding protein
BBB49_18560	COG4149	molybdate abc transporter
BBB49_18565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BBB49_18575	COG1447	Phosphotransferase system cellobiose-specific component IIA
BBB49_18580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBB49_18590	COG2723	6-phospho-beta-galactosidase activity
BBB49_18595	COG1940	carbohydrate kinase activity
BBB49_18605	COG1609	Transcriptional regulator
BBB49_18620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBB49_18635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBB49_18640	COG0167	dihydroorotate dehydrogenase activity
BBB49_18645	COG0402	S-adenosylhomocysteine deaminase activity
BBB49_18660	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BBB49_18675	COG0402	S-adenosylhomocysteine deaminase activity
BBB49_18680	COG1132	(ABC) transporter
BBB49_18695	COG3842	ATPase activity
BBB49_18700	COG0395	ABC-type sugar transport system, permease component
BBB49_18705	COG1175	transmembrane transport
BBB49_18710	COG1653	transport
BBB49_18715	COG0561	phosphatase activity
BBB49_18720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BBB49_18735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBB49_18750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BBB49_18770	COG0546	phosphoglycolate phosphatase activity
BBB49_18800	COG2814	Major facilitator Superfamily
BBB49_18805	COG1566	PFAM secretion protein HlyD family protein
BBB49_18820	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BBB49_18835	COG0726	polysaccharide deacetylase
BBB49_18845	COG3647	Membrane
BBB49_18860	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBB49_18870	COG0583	DNA-binding transcription factor activity
BBB49_18900	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBB49_18905	COG1518	maintenance of DNA repeat elements
BBB49_18915	COG1203	CRISPR-associated helicase, Cas3
BBB49_18975	COG3279	Response regulator of the LytR AlgR family
BBB49_18985	COG1136	(ABC) transporter
BBB49_18990	COG5002	protein histidine kinase activity
BBB49_18990	COG3850	Histidine kinase
BBB49_18995	COG0745	RESPONSE REGULATOR receiver
BBB49_19010	COG1874	Beta-galactosidase
BBB49_19025	COG0395	ABC-type sugar transport system, permease component
BBB49_19030	COG4209	transmembrane transport
BBB49_19035	COG4753	response regulator
BBB49_19035	COG2207	Transcriptional regulator
BBB49_19040	COG2972	Histidine kinase
BBB49_19150	COG5301	cellulose 1,4-beta-cellobiosidase activity
BBB49_19290	COG5484	DNA packaging
BBB49_19330	COG4974	Belongs to the 'phage' integrase family
BBB49_19440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBB49_19455	COG2002	toxin-antitoxin pair type II binding
BBB49_19515	COG1120	ATPase activity
BBB49_19520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBB49_19525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBB49_19530	COG0534	Mate efflux family protein
BBB49_19535	COG0534	Mate efflux family protein
BBB49_19540	COG2207	Transcriptional regulator
BBB49_19540	COG1917	Cupin 2, conserved barrel domain protein
BBB49_19550	COG1737	Transcriptional regulator
BBB49_19555	COG1737	Transcriptional regulator
BBB49_19560	COG2190	(PTS) system
BBB49_19560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBB49_19560	COG1263	PTS System
BBB49_19565	COG1486	melibiose metabolic process
BBB49_19585	COG1733	regulation of RNA biosynthetic process
BBB49_19615	COG4185	zeta toxin
BBB49_19630	COG2267	carboxylic ester hydrolase activity
BBB49_19635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BBB49_19640	COG0673	inositol 2-dehydrogenase activity
BBB49_19645	COG0673	inositol 2-dehydrogenase activity
BBB49_19655	COG1122	ATPase activity
BBB49_19665	COG0310	cobalt ion transport
BBB49_19670	COG1606	tRNA processing
BBB49_19675	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BBB49_19680	COG1691	(AIR) carboxylase
BBB49_19705	COG1132	(ABC) transporter
BBB49_19710	COG1132	(ABC) transporter
BBB49_19715	COG3866	Pectate lyase
BBB49_19735	COG1733	regulation of RNA biosynthetic process
BBB49_19745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBB49_19760	COG1940	carbohydrate kinase activity
BBB49_19765	COG1070	Carbohydrate kinase
BBB49_19770	COG0039	L-malate dehydrogenase activity
BBB49_19820	COG5002	protein histidine kinase activity
BBB49_19825	COG0745	RESPONSE REGULATOR receiver
BBB49_19830	COG0243	molybdopterin cofactor binding
BBB49_19835	COG0745	RESPONSE REGULATOR receiver
BBB49_19840	COG5002	protein histidine kinase activity
BBB49_19850	COG0656	L-ascorbic acid biosynthetic process
BBB49_19865	COG0840	transmembrane signaling receptor activity