locus-tag	class	description
CPR_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CPR_0004	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CPR_0006	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPR_0007	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPR_0010	ENOG4105DHT	Metal Dependent Phosphohydrolase
CPR_0026	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CPR_0027	ENOG4105EQI	Metal Dependent Phosphohydrolase
CPR_0028	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
CPR_0036	ENOG4108JU6	CBS domain protein
CPR_0037	ENOG4108Z6B	deaminase
CPR_0042	ENOG4105CKI	cobalamin synthesis protein
CPR_0044	ENOG4108PJD	permease
CPR_0053	ENOG4108RDQ	ABC transporter
CPR_0054	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CPR_0055	ENOG4105C6E	dna polymerase iii
CPR_0057	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CPR_0064	ENOG4108JQ1	Dehydrogenase
CPR_0066	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CPR_0067	ENOG4105CUZ	uba thif-type nad fad binding protein
CPR_0069	ENOG4105D9U	N-acetyltransferase
CPR_0070	ENOG4105ZMH	deoxynucleoside kinase
CPR_0072	ENOG4107QKW	extracellular solute-binding protein family 1
CPR_0075	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CPR_0079	ENOG4105D5Q	Arginine ornithine antiporter
CPR_0089	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CPR_0092	ENOG4105C5Y	PTS System
CPR_0096	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CPR_0098	ENOG4105DKQ	ROK family
CPR_0099	ENOG4105KY8	Rubrerythrin
CPR_0100	ENOG4105CVJ	phosphoglycerate mutase
CPR_0108	ENOG4105D41	biosynthesis protein thiH
CPR_0110	ENOG4105PTM	secreted protein
CPR_0113	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CPR_0117	ENOG4105CJZ	response regulator
CPR_0119	ENOG4105C19	ABC transporter
CPR_0126	ENOG4105D7V	transposase
CPR_0136	ENOG4105C5H	ABC transporter
CPR_0137	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CPR_0140	ENOG4105C6K	Malic enzyme
CPR_0142	ENOG4105CMU	LysR family (Transcriptional regulator
CPR_0155	ENOG4105E5D	amino acid
CPR_0156	ENOG4105C4C	beta-galactosidase
CPR_0165	ENOG4105C28	cystathionine
CPR_0168	ENOG4105D7V	transposase
CPR_0172	ENOG4105CJ1	ABC, transporter
CPR_0173	ENOG4108RCM	Nitroreductase
CPR_0176	ENOG4107RJ1	sodium solute
CPR_0177	ENOG4105XEP	YhcH YjgK YiaL family protein
CPR_0182	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
CPR_0184	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
CPR_0188	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
CPR_0189	ENOG4105DR5	peptidase
CPR_0202	ENOG4105D64	Mechanosensitive ion channel
CPR_0205	ENOG4105EYH	Exonuclease
CPR_0207	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CPR_0214	ENOG4105E0A	ABC, transporter
CPR_0215	ENOG4108JJ9	ABC, transporter
CPR_0216	ENOG4105BZ1	(ABC) transporter
CPR_0217	ENOG4105WD1	Membrane
CPR_0222	ENOG4105CXY	transporter
CPR_0223	ENOG4105C4Y	ABC transporter
CPR_0225	ENOG4105BZU	Histidine kinase
CPR_0226	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CPR_0227	ENOG4107RWR	Sodium hydrogen exchanger
CPR_0235	ENOG4105BZU	Histidine kinase
CPR_0236	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CPR_0238	ENOG4105CFG	Acts as a chaperone (By similarity)
CPR_0245	ENOG4105D7V	transposase
CPR_0247	ENOG4105D64	Mechanosensitive ion channel
CPR_0248	ENOG4106N3A	copper homeostasis protein cutc
CPR_0251	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CPR_0253	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CPR_0256	ENOG4107EF8	Glycosyl transferase (Group 1
CPR_0257	ENOG4107EF8	Glycosyl transferase (Group 1
CPR_0265	ENOG4105K4H	Nlp p60 protein
CPR_0266	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CPR_0267	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CPR_0268	ENOG4105KRN	Transcriptional regulator, abrb family
CPR_0271	ENOG4108KGH	TRANSCRIPTIONal
CPR_0272	ENOG4107U9T	Pfam:Ribonuclease_BN
CPR_0273	ENOG4105CMR	udp-glucose 4-epimerase
CPR_0274	ENOG4108UUM	single-stranded DNA-binding protein
CPR_0275	ENOG4105CNW	domain protein
CPR_0283	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CPR_0286	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
CPR_0287	ENOG4108HHA	Transketolase
CPR_0288	ENOG4108IUS	Transketolase
CPR_0290	ENOG4108JYZ	YitT family
CPR_0291	ENOG4105CAK	Cell division ATP-binding protein ftsE
CPR_0292	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CPR_0297	ENOG4108IUW	ABC transporter
CPR_0301	ENOG41073TP	transcriptional regulator
CPR_0303	ENOG4105BZJ	Electron transfer flavoprotein
CPR_0305	ENOG4105CQB	FAD linked oxidase domain protein
CPR_0311	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CPR_0313	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
CPR_0326	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CPR_0328	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CPR_0330	ENOG4105HZM	Fha domain containing protein
CPR_0332	ENOG4105CJN	penicillin-binding protein
CPR_0336	ENOG4105CHW	UPF0052 protein
CPR_0337	ENOG4105CIE	May be required for sporulation (By similarity)
CPR_0339	ENOG4105C0B	DNA polymerase III (alpha subunit)
CPR_0340	ENOG4105C0B	DNA polymerase III (alpha subunit)
CPR_0342	ENOG4105CA9	Pyruvate kinase
CPR_0344	ENOG4108UU4	oxidoreductase (Short chain dehydrogenase reductase family)
CPR_0345	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CPR_0351	ENOG4105D85	methylase
CPR_0360	ENOG4107WCA	isomerase
CPR_0362	ENOG4105CCI	Myosin-Cross-Reactive Antigen
CPR_0364	ENOG4105BZ1	(ABC) transporter
CPR_0366	ENOG4105XSJ	toxin secretion phage lysis holin
CPR_0367	ENOG4107BJW	polysaccharide deacetylase
CPR_0369	ENOG4105DRR	Transcriptional regulator, GntR family
CPR_0370	ENOG4108I5U	Uridine phosphorylase
CPR_0372	ENOG4105D5Q	Arginine ornithine antiporter
CPR_0373	ENOG41072DM	histidine decarboxylase
CPR_0378	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CPR_0382	ENOG4108RS6	transposase
CPR_0389	ENOG4107AYK	membrAne
CPR_0391	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CPR_0392	ENOG4105CHR	reductase
CPR_0395	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CPR_0396	ENOG4105EP8	Glycosyl Hydrolase Family 88
CPR_0397	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
CPR_0399	ENOG4105F3R	pts system mannose fructose sorbose family iid
CPR_0403	ENOG4108M60	Transcriptional regulator
CPR_0404	ENOG4105DNP	FAD linked oxidase domain protein
CPR_0410	ENOG4108V2W	Carbonate dehydratase
CPR_0416	ENOG4105FKQ	transcriptional regulator
CPR_0418	ENOG4105CI1	PTS System
CPR_0420	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CPR_0429	ENOG4106HB6	Alpha beta hydrolase
CPR_0434	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
CPR_0436	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CPR_0437	ENOG4105DVE	abc transporter atp-binding protein
CPR_0440	ENOG4108UYE	Lactoylglutathione lyase
CPR_0442	ENOG4105C0A	alcohol dehydrogenase
CPR_0444	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CPR_0445	ENOG4108Z6Z	Transcriptional regulator
CPR_0449	ENOG4105BZU	Histidine kinase
CPR_0452	ENOG4105HTX	biosynthesis protein
CPR_0453	ENOG4107YJ4	chain length determinant protein
CPR_0454	ENOG4105D3Q	Sugar transferase
CPR_0458	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
CPR_0459	ENOG4105CG5	Glycosyl transferase (Group 1
CPR_0463	ENOG4105KPE	licD family
CPR_0465	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CPR_0468	ENOG4105CMR	udp-glucose 4-epimerase
CPR_0469	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CPR_0472	ENOG4105D7V	transposase
CPR_0474	ENOG4108R6W	Transcriptional regulator, ARAC family
CPR_0477	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
CPR_0478	ENOG4105DRS	transport system, permease
CPR_0479	ENOG4105KFN	sortase, SrtB family
CPR_0486	ENOG4105DY9	regulatoR
CPR_0489	ENOG4106ETB	IIa component
CPR_0492	ENOG4108X4Q	Hydrolase
CPR_0495	ENOG4105BZ1	(ABC) transporter
CPR_0499	ENOG4105C5I	Dehydrogenase
CPR_0500	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CPR_0501	ENOG4108MRH	transcriptional regulatory protein
CPR_0506	ENOG4105D7V	transposase
CPR_0507	ENOG4107S8T	NAD-dependent 4-hydroxybutyrate dehydrogenase
CPR_0510	ENOG4105DUX	Transporter
CPR_0512	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CPR_0514	ENOG4105CXN	decarboxylase
CPR_0516	ENOG4105CYW	agmatinase
CPR_0517	ENOG410696E	Membrane
CPR_0518	ENOG4105C59	p-type ATPase
CPR_0522	ENOG4105E90	ABC transporter
CPR_0523	ENOG4105JVQ	RNA Polymerase
CPR_0525	ENOG4105C5Y	PTS System
CPR_0527	ENOG4107414	GntR family transcriptional regulator
CPR_0528	ENOG4105CJN	penicillin-binding protein
CPR_0530	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CPR_0531	ENOG4108R6K	riboflavin synthase, subunit alpha
CPR_0532	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CPR_0534	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
CPR_0537	ENOG4105CT8	Phosphorylase
CPR_0538	ENOG4105C2F	Histidine kinase
CPR_0539	ENOG4105EQD	regulatoR
CPR_0543	ENOG4108N5C	SNARE associated Golgi protein-related protein
CPR_0545	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
CPR_0547	ENOG4105D7V	transposase
CPR_0549	ENOG4105CJ3	phosphate transporter
CPR_0550	ENOG4105DM4	PTS System
CPR_0551	ENOG4105DE4	1-phosphofructokinase
CPR_0552	ENOG4105E98	transcriptional regulator DeoR family
CPR_0554	ENOG4105C02	permease
CPR_0556	ENOG4107R4J	Chloride channel
CPR_0558	ENOG4105KT7	mgtC SapB transporter
CPR_0561	ENOG4105E09	nadh pyrophosphatase
CPR_0562	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CPR_0565	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CPR_0566	ENOG4105EEM	helicase
CPR_0567	ENOG4105CT1	(ABC) transporter
CPR_0568	ENOG4105E5Q	amino acid AbC transporter
CPR_0569	ENOG4105CDA	abc transporter atp-binding protein
CPR_0570	ENOG4105E0M	Sulfatase
CPR_0571	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CPR_0575	ENOG4105E0M	Sulfatase
CPR_0577	ENOG4105DFM	M18 family aminopeptidase
CPR_0580	ENOG4105EYF	MMPL domain protein
CPR_0581	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CPR_0583	ENOG410667J	hydrolase
CPR_0584	ENOG4105D3Q	Sugar transferase
CPR_0585	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
CPR_0586	ENOG4105CG5	Glycosyl transferase (Group 1
CPR_0588	ENOG4107XU6	Glycosyl transferase (Group 1
CPR_0589	ENOG4105KPE	licD family
CPR_0592	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
CPR_0594	ENOG4108KN0	Choline kinase
CPR_0602	ENOG4105C4X	radical SAM domain protein
CPR_0603	ENOG4105CVA	phosphate
CPR_0604	ENOG4105CVA	phosphate
CPR_0605	ENOG4105C8U	phosphate abc transporter
CPR_0606	ENOG4105E2Z	phosphate ABC transporter (Permease
CPR_0607	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CPR_0608	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CPR_0609	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CPR_0611	ENOG4108Z29	Flavodoxin
CPR_0615	ENOG4105E1K	spore germination protein
CPR_0623	ENOG4105CDA	abc transporter atp-binding protein
CPR_0624	ENOG4105EZM	VWA-like domain (DUF2201)
CPR_0626	ENOG4105D7V	transposase
CPR_0630	ENOG4105D5G	Transposase
CPR_0636	ENOG4105G0K	glycine radical enzyme YjjI family
CPR_0637	ENOG41076CZ	activating enzyme
CPR_0651	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CPR_0667	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CPR_0669	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CPR_0670	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CPR_0674	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CPR_0676	ENOG4105C12	Phosphoribosylglycinamide synthetase
CPR_0679	ENOG4105D7V	transposase
CPR_0682	ENOG4105KY8	Rubrerythrin
CPR_0687	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
CPR_0688	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
CPR_0691	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CPR_0692	ENOG4105CQC	Prephenate dehydratase
CPR_0698	ENOG4108IUX	(ABC) transporter
CPR_0699	ENOG4105RHA	ABC transporter, permease
CPR_0700	ENOG4108ZB6	transcriptional regulator AsnC family
CPR_0701	ENOG4105CHM	Aminotransferase
CPR_0705	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CPR_0706	ENOG4105K64	Glycosyl transferase, family 2
CPR_0707	ENOG4105C02	permease
CPR_0708	ENOG4105E98	transcriptional regulator DeoR family
CPR_0709	ENOG4105J7I	hydrolase
CPR_0711	ENOG4105D7V	transposase
CPR_0715	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CPR_0719	ENOG4105X5K	response regulator receiver protein
CPR_0721	ENOG4107QIV	Cytochrome c biogenesis protein
CPR_0723	ENOG4105D7V	transposase
CPR_0727	ENOG4105ST3	Transcriptional regulator
CPR_0735	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CPR_0737	ENOG4105DZC	cytosine deaminase
CPR_0740	ENOG4107YHD	transcriptional regulator
CPR_0741	ENOG4107YDN	peptide deformylase
CPR_0743	ENOG4105PAD	Hydrolase
CPR_0748	ENOG4105CT4	transporter
CPR_0751	ENOG4105CY2	Citrate transporter
CPR_0753	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
CPR_0754	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CPR_0756	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CPR_0757	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CPR_0771	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CPR_0772	ENOG4105D7V	transposase
CPR_0776	ENOG4105EUB	pirin domain protein
CPR_0778	ENOG4108MES	Periplasmic binding protein
CPR_0779	ENOG4105DQ5	transport system permease protein
CPR_0780	ENOG4108IHU	transport system permease protein
CPR_0781	ENOG4105E0A	ABC, transporter
CPR_0782	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CPR_0794	ENOG4108MES	Periplasmic binding protein
CPR_0795	ENOG4105DQ5	transport system permease protein
CPR_0796	ENOG4105EHG	Permease protein
CPR_0797	ENOG4105E0A	ABC, transporter
CPR_0803	ENOG4105J7I	hydrolase
CPR_0805	ENOG4105ETZ	PTS System
CPR_0806	ENOG4105F3R	pts system mannose fructose sorbose family iid
CPR_0816	ENOG4105K4I	Scp-like extracellular
CPR_0819	ENOG4105EYF	MMPL domain protein
CPR_0822	ENOG4105DQ6	Transposase
CPR_0827	ENOG4108UXE	Protein tyrosine phosphatase
CPR_0828	ENOG4105UQX	Mate efflux family protein
CPR_0831	ENOG4105EWM	Histidine kinase
CPR_0840	ENOG4108RAC	Rubrerythrin
CPR_0842	ENOG4107QW4	alcohol dehydrogenase
CPR_0844	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
CPR_0845	ENOG4107QQ0	gntp family
CPR_0846	ENOG4105BZW	Glycerate kinase
CPR_0847	ENOG4105C1J	atp-dependent rna helicase
CPR_0848	ENOG4105UQX	Mate efflux family protein
CPR_0850	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
CPR_0854	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
CPR_0857	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
CPR_0858	ENOG41080VW	acetyltransferase
CPR_0866	ENOG4108N5C	SNARE associated Golgi protein-related protein
CPR_0867	ENOG4108V06	Glutathione peroxidase
CPR_0868	ENOG4108M8H	domain protein
CPR_0870	ENOG41082BM	Transcriptional regulator, arsr family
CPR_0877	ENOG4105W5A	BNR Asp-box repeat protein
CPR_0879	ENOG4108TYN	CAAX amino terminal protease family protein
CPR_0886	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CPR_0889	ENOG4105D7V	transposase
CPR_0898	ENOG4105M6F	mutator MutT protein
CPR_0904	ENOG4108JE9	extracellular solute-binding protein family 1
CPR_0906	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
CPR_0907	ENOG4108IJ9	(ABC) transporter
CPR_0917	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CPR_0927	ENOG4105C0A	alcohol dehydrogenase
CPR_0931	ENOG4108M8H	domain protein
CPR_0934	ENOG4105WEF	catalase
CPR_0974	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CPR_0980	ENOG4105KVH	Transcriptional regulator
CPR_0983	ENOG41076HS	cation diffusion facilitator family transporter
CPR_0984	ENOG4107QN2	dihydrolipoyl dehydrogenase
CPR_0987	ENOG4105FE9	pseudouridine synthase
CPR_0989	ENOG4105D7V	transposase
CPR_0991	ENOG4105CHR	reductase
CPR_0994	ENOG4105DQR	SNARE associated Golgi
CPR_0996	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CPR_0997	ENOG4108RCM	Nitroreductase
CPR_0999	ENOG4105E8R	UPF0173 metal-dependent hydrolase
CPR_1001	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CPR_1002	ENOG4108HRK	Histidine kinase
CPR_1003	ENOG4105WH1	Two component transcriptional regulator luxr family
CPR_1005	ENOG4105YCI	dehydratase medium subunit
CPR_1006	ENOG4108ZFT	Dehydratase small subunit
CPR_1007	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
CPR_1012	ENOG4105E5D	amino acid
CPR_1013	ENOG4105I7V	membrAne
CPR_1019	ENOG4107R6U	sodium dicarboxylate symporter
CPR_1020	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CPR_1023	ENOG4105BZU	Histidine kinase
CPR_1025	ENOG4105CBX	hi0933 family
CPR_1031	ENOG4105D7V	transposase
CPR_1032	ENOG4105K56	Transcriptional regulator
CPR_1034	ENOG4107SC7	Inner membrane transporter yjeM
CPR_1041	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CPR_1049	ENOG4105D7V	transposase
CPR_1054	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CPR_1055	ENOG4105BZU	Histidine kinase
CPR_1059	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CPR_1062	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CPR_1074	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CPR_1075	ENOG4105D7N	magnesium and cobalt transport protein CorA
CPR_1076	ENOG4105DFM	M18 family aminopeptidase
CPR_1089	ENOG4105KME	endoribonuclease L-psp
CPR_1091	ENOG4105CNW	domain protein
CPR_1092	ENOG4105DB7	PHP domain protein
CPR_1093	ENOG4105DDQ	anthranilate synthase
CPR_1094	ENOG4105CRQ	synthase (Component I)
CPR_1095	ENOG4105F0I	Aminotransferase
CPR_1098	ENOG4105EEI	dihydropteroate synthase
CPR_1099	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CPR_1102	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CPR_1105	ENOG4107YCR	Transcriptional regulator, ARSR family
CPR_1106	ENOG4105CH2	amidohydrolase
CPR_1108	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CPR_1114	ENOG4107QZB	decarboxylase
CPR_1115	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CPR_1116	ENOG4105EHG	Permease protein
CPR_1117	ENOG4105E0A	ABC, transporter
CPR_1120	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CPR_1123	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CPR_1124	ENOG4107RM6	sulfurtransferase
CPR_1128	ENOG4108W76	histidinol phosphate phosphatase hisj family
CPR_1130	ENOG4108DWA	Nad synthetase
CPR_1133	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CPR_1134	ENOG4107YWA	deoxycytidylate deaminase
CPR_1135	ENOG410834F	Transcriptional regulator
CPR_1137	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CPR_1138	ENOG4105CHR	reductase
CPR_1139	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CPR_1141	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CPR_1142	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CPR_1147	ENOG4105FE9	pseudouridine synthase
CPR_1150	ENOG4105CBX	hi0933 family
CPR_1160	ENOG4105DKT	Transcriptional regulator
CPR_1161	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
CPR_1162	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
CPR_1167	ENOG4105C6K	Malic enzyme
CPR_1175	ENOG4105CXI	aluminum resistance protein
CPR_1179	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPR_1181	ENOG4105C7B	Threonine dehydratase
CPR_1182	ENOG4108IQI	permease
CPR_1183	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CPR_1185	ENOG4108VW9	Membrane
CPR_1192	ENOG4105CGK	Exodeoxyribonuclease III
CPR_1193	ENOG4107WJM	-acetyltransferase
CPR_1196	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CPR_1197	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
CPR_1205	ENOG4105DG6	mannose-6-phosphate isomerase
CPR_1206	ENOG4105DMS	mur ligase
CPR_1207	ENOG4105F1K	Glutamine amidotransferase
CPR_1212	ENOG4107SC7	Inner membrane transporter yjeM
CPR_1218	ENOG4105C3S	Mate efflux family protein
CPR_1224	ENOG4105EI2	Pseudouridine synthase
CPR_1225	ENOG4105CH2	amidohydrolase
CPR_1226	ENOG4105C4R	Atp-dependent dna helicase
CPR_1227	ENOG4105DAP	Nicotinate phosphoribosyltransferase
CPR_1230	ENOG4105G5W	regulator Fur family
CPR_1231	ENOG4107QSE	Dipeptidase
CPR_1232	ENOG4105C2W	permease
CPR_1233	ENOG4108JTQ	reductase
CPR_1234	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CPR_1236	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CPR_1238	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
CPR_1241	ENOG41081F0	Precorrin-8x methylmutase
CPR_1242	ENOG4107PPM	cobalt chelatase
CPR_1243	ENOG41069ER	domain protein
CPR_1253	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CPR_1255	ENOG4105CJW	magnesium transporter
CPR_1263	ENOG4105BZ8	glutamate synthase
CPR_1264	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
CPR_1266	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CPR_1270	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CPR_1273	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CPR_1279	ENOG4108PCX	Major Facilitator
CPR_1280	ENOG4105FDP	GntR family transcriptional regulator
CPR_1281	ENOG4105D9N	nucleoside
CPR_1282	ENOG4105ME7	Membrane
CPR_1283	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
CPR_1287	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
CPR_1291	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CPR_1292	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CPR_1295	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CPR_1297	ENOG4105E5D	amino acid
CPR_1299	ENOG4105CP7	Triose-phosphate isomerase
CPR_1301	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CPR_1303	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPR_1306	ENOG4105DIH	basic membrane
CPR_1309	ENOG410667J	hydrolase
CPR_1310	ENOG41073R8	VanW family
CPR_1318	ENOG4105CSM	endonuclease III
CPR_1320	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CPR_1321	ENOG4105D7W	serine acetyltransferase
CPR_1322	ENOG4105C6T	cysteine synthase
CPR_1323	ENOG4105CJW	magnesium transporter
CPR_1324	ENOG4108HW3	(ABC) transporter
CPR_1325	ENOG4105E5Q	amino acid AbC transporter
CPR_1328	ENOG4105CBD	Diacylglycerol kinase
CPR_1329	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CPR_1332	ENOG4105ED1	spovr family
CPR_1334	ENOG4105CYN	Serine protein kinase
CPR_1335	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CPR_1341	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
CPR_1343	ENOG4107SDZ	Galactoside transport system permease protein mglC
CPR_1344	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CPR_1347	ENOG4105C22	threonyL-tRNA synthetase
CPR_1348	ENOG4105H67	Protein of unknown function (DUF421)
CPR_1353	ENOG4105K4H	Nlp p60 protein
CPR_1356	ENOG4108Z66	YbaK ebsC protein
CPR_1365	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CPR_1371	ENOG4108VXD	carboxy-peptidase
CPR_1382	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CPR_1383	ENOG4108IUQ	atp-dependent protease
CPR_1385	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CPR_1394	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CPR_1400	ENOG4105CMQ	Chloride channel
CPR_1405	ENOG4105C8I	hydrolase, family 38
CPR_1408	ENOG4105BZG	amino acid carrier protein
CPR_1409	ENOG4105FH5	Membrane
CPR_1410	ENOG4105KXX	peptidase s58 dmpa
CPR_1420	ENOG4105D52	delta-aminolevulinic acid dehydratase
CPR_1425	ENOG410810Y	Sulfite reductase
CPR_1426	ENOG4107SHJ	sulfite reductase subunit b
CPR_1427	ENOG4105D5B	Sulfite reductase, subunit A
CPR_1429	ENOG4107V9H	nitrite transporter
CPR_1432	ENOG4108MCI	Transcriptional regulator, ARAC family
CPR_1436	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CPR_1438	ENOG4107ZXI	Rhomboid family
CPR_1439	ENOG4105DPN	Oligoendopeptidase f
CPR_1442	ENOG4105FDK	ABC transporter
CPR_1443	ENOG4105FAV	ABC, transporter
CPR_1446	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
CPR_1448	ENOG4105C9B	Cysteine desulfurase
CPR_1449	ENOG4105C5H	ABC transporter
CPR_1450	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CPR_1453	ENOG4108UT2	hemolysin iii
CPR_1454	ENOG4105DUM	transcriptional regulator, lysR family
CPR_1459	ENOG4105CHH	sulfate transporter
CPR_1464	ENOG4105E2Y	ABC, transporter
CPR_1475	ENOG4107T5V	SNARE associated Golgi
CPR_1476	ENOG4105KHU	inner membrane protein YohD
CPR_1477	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CPR_1480	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CPR_1482	ENOG4105DY9	regulatoR
CPR_1485	ENOG41069ER	domain protein
CPR_1487	ENOG4105C5H	ABC transporter
CPR_1493	ENOG4105BZU	Histidine kinase
CPR_1495	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
CPR_1499	ENOG4107R37	Glutamate dehydrogenase
CPR_1501	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CPR_1508	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
CPR_1513	ENOG4105C5Y	PTS System
CPR_1516	ENOG4105PTM	secreted protein
CPR_1517	ENOG4106F1P	AAA ATPase, central domain protein
CPR_1518	ENOG4108J2R	molybdopterin oxidoreductase
CPR_1519	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CPR_1522	ENOG4108IUM	Glycogen debranching enzyme
CPR_1527	ENOG4108QEG	Membrane
CPR_1528	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CPR_1530	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CPR_1539	ENOG4107ZE5	PPIases accelerate the folding of proteins
CPR_1547	ENOG4105C7N	Xanthine uracil vitamin C permease
CPR_1550	ENOG4105UIB	(ABC) transporter
CPR_1551	ENOG4108JQ9	ABC transporter
CPR_1552	ENOG4107TFB	basic membrane
CPR_1557	ENOG4107YZP	Rhodanese domain protein
CPR_1558	ENOG4108IUM	Glycogen debranching enzyme
CPR_1565	ENOG4105D7V	transposase
CPR_1569	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CPR_1573	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CPR_1574	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CPR_1582	ENOG4108ZJ4	polysaccharide deacetylase
CPR_1583	ENOG4105D7V	transposase
CPR_1587	ENOG4105E4C	Lytic transglycosylase catalytic
CPR_1591	ENOG4105EEM	helicase
CPR_1598	ENOG4105ETE	Transcriptional regulator (LacI family
CPR_1599	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CPR_1600	ENOG4105CNN	ABC, transporter
CPR_1603	ENOG4108RVA	ribokinase
CPR_1605	ENOG4105ESV	Glycosyl transferase, family 4
CPR_1608	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
CPR_1622	ENOG4108Z0R	Transferase
CPR_1625	ENOG4108VVK	transcriptional Regulator, AsnC
CPR_1626	ENOG4105WG9	Conserved Protein
CPR_1636	ENOG4108Z4T	Peptidase M50
CPR_1637	ENOG4108IAB	Phoh family
CPR_1643	ENOG4105MCT	stage V sporulation protein S
CPR_1646	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CPR_1649	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
CPR_1653	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CPR_1654	ENOG4105DTN	riboflavin biosynthesis protein ribF
CPR_1656	ENOG4105SFS	phosphoesterase RecJ domain protein
CPR_1657	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CPR_1658	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CPR_1660	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
CPR_1661	ENOG4105CHV	Transcription elongation factor NusA
CPR_1667	ENOG4105KNE	Phosphatidate cytidylyltransferase
CPR_1669	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CPR_1672	ENOG4105CE9	30S ribosomal protein S2
CPR_1673	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
CPR_1674	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CPR_1675	ENOG4105C79	DNA protecting protein DprA
CPR_1676	ENOG4105C0P	Mg chelatase subunit ChlI
CPR_1679	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CPR_1680	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CPR_1684	ENOG4105K5M	30s ribosomal protein S16
CPR_1687	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CPR_1691	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CPR_1693	ENOG41067VY	50S ribosomal protein L32
CPR_1696	ENOG4108IJ2	phosphate acetyltransferase
CPR_1701	ENOG4106H78	methyltransferase
CPR_1702	ENOG4105CB5	ATP-dependent DNA helicase recG
CPR_1703	ENOG4105DP4	dak2 domain fusion protein ylov
CPR_1707	ENOG4105DJV	ribulose-phosphate 3-epimerase
CPR_1710	ENOG4108ZF3	Phosphatase
CPR_1712	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CPR_1716	ENOG4105C25	Primosomal protein n'
CPR_1717	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CPR_1718	ENOG41084KE	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CPR_1721	ENOG4105DSJ	YicC domain protein
CPR_1722	ENOG4105C7N	Xanthine uracil vitamin C permease
CPR_1723	ENOG4105HDK	L-asparaginase
CPR_1724	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
CPR_1726	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CPR_1728	ENOG4105BZU	Histidine kinase
CPR_1729	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CPR_1731	ENOG4108BIK	prc-barrel domain-containing protein
CPR_1732	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPR_1733	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPR_1735	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CPR_1737	ENOG4105CZX	twitching motility protein
CPR_1738	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPR_1741	ENOG4105CFP	Peptidase U32
CPR_1742	ENOG4108VQJ	O-methyltransferase
CPR_1743	ENOG4105HHA	aminodeoxychorismate lyase
CPR_1744	ENOG4105CI3	gtp-binding protein typa
CPR_1745	ENOG4105CN5	Metallo-Beta-Lactamase
CPR_1746	ENOG4105I3K	Ferric uptake regulator, Fur family
CPR_1748	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CPR_1751	ENOG4105C02	permease
CPR_1754	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CPR_1757	ENOG4105D1H	recombination factor protein RarA
CPR_1758	ENOG4105BZU	Histidine kinase
CPR_1763	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CPR_1767	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CPR_1768	ENOG4105CBX	hi0933 family
CPR_1770	ENOG4105DZ1	carboxypeptidase
CPR_1772	ENOG4105KBJ	sporulation protein ytfj
CPR_1775	ENOG4105DZ1	carboxypeptidase
CPR_1776	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CPR_1777	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPR_1779	ENOG4108YZ4	nudix hydrolase
CPR_1781	ENOG4107QQR	Sporulation
CPR_1782	ENOG4105S1Z	Stage IV sporulation protein B
CPR_1783	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CPR_1786	ENOG4105DX0	Hemolysin A
CPR_1788	ENOG4105CTB	Polyprenyl synthetase
CPR_1789	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CPR_1793	ENOG4108ZSR	alkaline shock protein
CPR_1798	ENOG4105KQ4	Stage iii sporulation protein ad
CPR_1799	ENOG4108CQH	stage III sporulation protein AC
CPR_1801	ENOG4105CD2	stage iii sporulation protein aa
CPR_1803	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CPR_1812	ENOG4107QHF	type ii secretion system protein e
CPR_1815	ENOG4105F23	Fibronectin-binding protein
CPR_1816	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CPR_1817	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CPR_1818	ENOG4105C34	Pseudouridine synthase
CPR_1821	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CPR_1822	ENOG4105DFA	alanine racemase domain protein
CPR_1824	ENOG4105K67	small basic protein
CPR_1826	ENOG4108Z36	domain protein, FtsQ-type
CPR_1827	ENOG4105CNI	cell division protein FtsW
CPR_1829	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
CPR_1831	ENOG4105CJN	penicillin-binding protein
CPR_1833	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CPR_1835	ENOG4105C3G	gtp-binding protein
CPR_1845	ENOG4105EWC	Purine nucleoside phosphorylase
CPR_1846	ENOG4105CJN	penicillin-binding protein
CPR_1848	ENOG4105CFP	Peptidase U32
CPR_1849	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
CPR_1853	ENOG4108RWN	rrna methyltransferase
CPR_1854	ENOG4107ZYR	domain protein
CPR_1856	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CPR_1857	ENOG4105VJV	50s ribosomal protein L35
CPR_1862	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CPR_1871	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CPR_1874	ENOG4105CHM	Aminotransferase
CPR_1875	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CPR_1881	ENOG4108RCF	TRANSCRIPTIONal
CPR_1882	ENOG4108UT2	hemolysin iii
CPR_1884	ENOG4105CMQ	Chloride channel
CPR_1885	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CPR_1890	ENOG4105C1V	Peptidase, M16
CPR_1891	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPR_1892	ENOG4105BZU	Histidine kinase
CPR_1893	ENOG4105CHR	reductase
CPR_1896	ENOG4105DWK	Membrane
CPR_1898	ENOG4105VPX	protein, conserved in bacteria
CPR_1901	ENOG4105D4P	Coproporphyrinogen iii oxidase
CPR_1902	ENOG4105C5X	domain protein
CPR_1903	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CPR_1904	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CPR_1905	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CPR_1907	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CPR_1908	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CPR_1911	ENOG4105VIE	preprotein translocase, subunit YajC
CPR_1912	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CPR_1917	ENOG4105CGH	5'-nucleotidase
CPR_1918	ENOG4105CGH	5'-nucleotidase
CPR_1923	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CPR_1924	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CPR_1927	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CPR_1928	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CPR_1936	ENOG4105F38	ABC transporter, permease
CPR_1937	ENOG4105D38	putrescine abc transporter
CPR_1938	ENOG4107RUE	extracellular solute-binding protein family 1
CPR_1940	ENOG41084AG	Acylphosphatase
CPR_1943	ENOG4105DZ1	carboxypeptidase
CPR_1948	ENOG41067MG	lrgb family
CPR_1950	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CPR_1951	ENOG4105CI2	imidazolone-5-propionate hydrolase
CPR_1952	ENOG4105KAV	tspo and mbr like protein
CPR_1953	ENOG4105US7	Histidine kinase
CPR_1954	ENOG4105BZU	Histidine kinase
CPR_1956	ENOG4105E5G	Alpha beta hydrolase fold
CPR_1962	ENOG4105C2M	dna polymerase I
CPR_1967	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
CPR_1971	ENOG4105DU0	nucleoside hydrolase
CPR_1975	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPR_1976	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CPR_1979	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CPR_1983	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CPR_1989	ENOG4107YR5	Diacylglycerol kinase
CPR_1991	ENOG4105CTJ	Metal Dependent Phosphohydrolase
CPR_1994	ENOG4105KTH	gatB Yqey
CPR_1995	ENOG4105VCC	30S ribosomal protein S21
CPR_1996	ENOG4107YU2	histidine triad (hIT) protein
CPR_1997	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CPR_2000	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
CPR_2003	ENOG4105CZV	ABC transporter
CPR_2008	ENOG4105CSA	Coproporphyrinogen iii oxidase
CPR_2014	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CPR_2018	ENOG4105CZ3	stage V sporulation protein ad
CPR_2019	ENOG41090VF	Stage v sporulation protein ac
CPR_2020	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPR_2022	ENOG41082AN	stage II sporulation protein
CPR_2023	ENOG4105DAN	ATP-dependent protease
CPR_2029	ENOG4105CVK	Glutamate decarboxylase
CPR_2030	ENOG4107UNS	conserved inner membrane protein
CPR_2031	ENOG4105E5D	amino acid
CPR_2036	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CPR_2039	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPR_2040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPR_2041	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CPR_2046	ENOG4105E5D	amino acid
CPR_2049	ENOG4105C8I	hydrolase, family 38
CPR_2050	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
CPR_2053	ENOG4105E0C	molybdate abc transporter
CPR_2054	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CPR_2055	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CPR_2056	ENOG4105EQD	regulatoR
CPR_2057	ENOG4105C2F	Histidine kinase
CPR_2059	ENOG4108RMH	femAB family
CPR_2060	ENOG4105VUN	Transcriptional regulator
CPR_2062	ENOG4105EAB	amino acid AbC transporter
CPR_2065	ENOG4105W7A	Protein of unknown function (DUF503)
CPR_2067	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CPR_2073	ENOG4105BZ8	glutamate synthase
CPR_2074	ENOG4106MCE	EamA-like transporter family
CPR_2076	ENOG4105BZU	Histidine kinase
CPR_2077	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPR_2080	ENOG4107WD8	ABC transporter, permease
CPR_2084	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CPR_2087	ENOG4105KQC	Competence protein
CPR_2088	ENOG4105DZ1	carboxypeptidase
CPR_2089	ENOG4105EMS	pseudouridine synthase
CPR_2090	ENOG4108KGH	TRANSCRIPTIONal
CPR_2091	ENOG4108WF2	Metal Dependent Phosphohydrolase
CPR_2093	ENOG410812S	Rna-binding protein
CPR_2094	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CPR_2095	ENOG4105K46	50S ribosomal protein l27
CPR_2097	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CPR_2098	ENOG4105C03	ribonuclease
CPR_2103	ENOG4105CNI	cell division protein FtsW
CPR_2105	ENOG4107QMS	site-determining protein
CPR_2106	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CPR_2107	ENOG4107RF6	penicillin-binding protein
CPR_2107	ENOG4107RF6	penicillin-binding protein
CPR_2110	ENOG4105DFF	Rod shape-determining protein mreb
CPR_2114	ENOG4105DB7	PHP domain protein
CPR_2115	ENOG4105CIN	aminoacyl-histidine dipeptidase
CPR_2117	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CPR_2125	ENOG4105DSE	periplasmic solute binding protein
CPR_2126	ENOG4106D4I	domain protein
CPR_2132	ENOG4105K8N	protein family UPF0079, ATPase
CPR_2133	ENOG41072GX	Peptidase M22 Glycoprotease
CPR_2134	ENOG410801F	ribosomal-protein-alanine acetyltransferase
CPR_2137	ENOG4105IIU	Aminopeptidase
CPR_2143	ENOG4105C7H	Helicase, RecD TraA family
CPR_2144	ENOG4105CE4	GlcNAc 6-P deacetylase
CPR_2145	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CPR_2156	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
CPR_2157	ENOG4108K5P	(LipO)protein
CPR_2163	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CPR_2166	ENOG4108405	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CPR_2168	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
CPR_2170	ENOG4105CHU	acetyl-coa acetyltransferase
CPR_2171	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CPR_2173	ENOG4108YZG	isomerase
CPR_2174	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CPR_2176	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CPR_2178	ENOG4107104	thymidine kinase
CPR_2179	ENOG41082DI	50s ribosomal protein l31
CPR_2180	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
CPR_2181	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CPR_2182	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CPR_2183	ENOG410684U	Domain of unknown function (DUF1934)
CPR_2184	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CPR_2185	ENOG4108ZXQ	stage ii sporulation protein r
CPR_2190	ENOG4105W42	Veg protein
CPR_2191	ENOG4105XFA	sporulation peptidase YabG
CPR_2192	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CPR_2193	ENOG4105CPK	Glycosyl transferase (Group 1
CPR_2197	ENOG4108TJN	glycosyl transferase group 1
CPR_2198	ENOG4105ENY	Ethanolamine utilization protein eutH
CPR_2200	ENOG4105C0H	protease
CPR_2205	ENOG4108JU3	Alkyl hydroperoxide reductase
CPR_2206	ENOG4105VFE	sira family
CPR_2207	ENOG4105E0M	Sulfatase
CPR_2209	ENOG4105BZU	Histidine kinase
CPR_2210	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CPR_2216	ENOG4105CIN	aminoacyl-histidine dipeptidase
CPR_2242	ENOG4105HJK	ABC transporter
CPR_2254	ENOG4108JQ7	(ABC) transporter
CPR_2255	ENOG4105C3U	ABC transporter
CPR_2256	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CPR_2259	ENOG4107QND	Nitrite extrusion protein
CPR_2261	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CPR_2271	ENOG4105D7Q	type ii secretion system
CPR_2272	ENOG4107QHF	type ii secretion system protein e
CPR_2275	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CPR_2281	ENOG4105VFR	signal peptidase
CPR_2282	ENOG4105BZ1	(ABC) transporter
CPR_2283	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CPR_2285	ENOG4105BZJ	Electron transfer flavoprotein
CPR_2286	ENOG4105C1G	acyl-Coa dehydrogenase
CPR_2287	ENOG4105E39	Enoyl-CoA hydratase
CPR_2289	ENOG4105C59	p-type ATPase
CPR_2294	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CPR_2295	ENOG4105CS2	ec 3.2.1.21
CPR_2296	ENOG4105C26	Dehydrogenase
CPR_2299	ENOG4105FE9	pseudouridine synthase
CPR_2303	ENOG4105DFD	Na H antiporter
CPR_2319	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CPR_2326	ENOG4105BZU	Histidine kinase
CPR_2327	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPR_2329	ENOG4105KGF	protein, YerC YecD
CPR_2333	ENOG4108IUJ	4-alpha-glucanotransferase
CPR_2335	ENOG4105ETE	Transcriptional regulator (LacI family
CPR_2336	ENOG4105EG2	ABC transporter, permease
CPR_2337	ENOG4105D56	permease protein
CPR_2338	ENOG4107FKK	extracellular solute-binding protein family 1
CPR_2339	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
CPR_2343	ENOG4107RE7	phosphate butyryltransferase
CPR_2344	ENOG4105DZ0	fad dependent oxidoreductase
CPR_2346	ENOG4105C8B	TIGR00159 family
CPR_2349	ENOG4105C3M	thioredoxin reductase
CPR_2350	ENOG4105K63	Thioredoxin
CPR_2351	ENOG4105DYB	Isoaspartyl dipeptidase
CPR_2352	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CPR_2353	ENOG4108JUB	Transcriptional regulator
CPR_2355	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CPR_2356	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CPR_2357	ENOG41080E8	Transcriptional regulator, Spx MgsR family
CPR_2360	ENOG4107AYK	membrAne
CPR_2363	ENOG4108UJD	30S ribosomal protein S9
CPR_2366	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
CPR_2369	ENOG4108ZT0	50S ribosomal protein l17
CPR_2370	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CPR_2372	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CPR_2373	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPR_2375	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CPR_2379	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CPR_2380	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CPR_2381	ENOG41084RK	50S ribosomal protein L30
CPR_2382	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CPR_2383	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CPR_2384	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CPR_2385	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CPR_2386	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CPR_2387	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CPR_2389	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CPR_2391	ENOG41082SA	50s ribosomal protein l29
CPR_2392	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CPR_2393	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CPR_2394	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CPR_2395	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CPR_2396	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPR_2397	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CPR_2400	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CPR_2402	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CPR_2404	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CPR_2405	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CPR_2406	ENOG4105XPM	ribosomal protein
CPR_2407	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CPR_2409	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CPR_2411	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CPR_2412	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CPR_2413	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CPR_2415	ENOG4105WDJ	50S ribosomal protein L33
CPR_2416	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CPR_2418	ENOG4105QIV	RNA polymerase
CPR_2420	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CPR_2422	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CPR_2427	ENOG4105CTP	PilT protein domain protein
CPR_2430	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CPR_2432	ENOG4105FDP	GntR family transcriptional regulator
CPR_2434	ENOG4105C26	Dehydrogenase
CPR_2441	ENOG4105E8R	UPF0173 metal-dependent hydrolase
CPR_2443	ENOG4105MA4	psp1 domain protein
CPR_2444	ENOG4107QRG	dna polymerase iii
CPR_2445	ENOG4105X0R	protein from nitrogen regulatory protein P-II
CPR_2447	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CPR_2448	ENOG4105CXN	decarboxylase
CPR_2453	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
CPR_2462	ENOG4107QW8	radical SAM domain protein
CPR_2464	ENOG4105EU2	peptidase U61 LD-carboxypeptidase A
CPR_2468	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CPR_2469	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CPR_2470	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CPR_2472	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CPR_2473	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CPR_2474	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CPR_2483	ENOG41060GV	RNA binding s1 domain protein
CPR_2487	ENOG41082I2	s4 domain protein
CPR_2489	ENOG4108IY2	MazG family
CPR_2491	ENOG4108M14	stage v sporulation protein t
CPR_2493	ENOG4108JA2	transcriptioN-repair coupling factor
CPR_2495	ENOG4105C0H	protease
CPR_2496	ENOG4105EB3	Histidine kinase
CPR_2497	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPR_2501	ENOG4105DFT	pur operon repressor
CPR_2505	ENOG4105D9N	nucleoside
CPR_2506	ENOG4105DC7	peptidase M24
CPR_2512	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CPR_2514	ENOG4107QI1	Mate efflux family protein
CPR_2516	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CPR_2517	ENOG4108R5T	secreted protein
CPR_2519	ENOG4105U3E	Transcriptional regulator
CPR_2520	ENOG410688J	Ferredoxin
CPR_2526	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CPR_2527	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
CPR_2528	ENOG41069ER	domain protein
CPR_2529	ENOG4105F8V	Hydrolase, tatD family
CPR_2530	ENOG4108UH6	UPF0754 membrane protein
CPR_2532	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CPR_2536	ENOG4107S6Z	Na H antiporter
CPR_2539	ENOG4107RAQ	aminopeptidase
CPR_2542	ENOG4108JIC	nucleoside recognition domain protein
CPR_2546	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CPR_2553	ENOG4105C5H	ABC transporter
CPR_2555	ENOG4105DR4	Methyltransferase
CPR_2560	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
CPR_2561	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CPR_2563	ENOG4105N5T	Radical SAM Protein
CPR_2565	ENOG4108K88	Membrane
CPR_2567	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
CPR_2570	ENOG4107ZE5	PPIases accelerate the folding of proteins
CPR_2573	ENOG4105C5F	glutamine synthetase
CPR_2579	ENOG4107QHI	-hydrogenase
CPR_2581	ENOG4105VCP	PTS System
CPR_2584	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CPR_2585	ENOG4108W6C	Dehydrogenase
CPR_2588	ENOG4105DWD	nucleoside recognition domain protein
CPR_2590	ENOG4108UW5	maltose o-acetyltransferase
CPR_2595	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CPR_2600	ENOG4105VCP	PTS System
CPR_2601	ENOG4105CK1	PTS System
CPR_2602	ENOG4105VZJ	PTS System
CPR_2603	ENOG4105CS2	ec 3.2.1.21
CPR_2606	ENOG4105ETE	Transcriptional regulator (LacI family
CPR_2613	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CPR_2615	ENOG4105Q2H	domain protein
CPR_2620	ENOG4108QT4	peptidase S8 and S53, subtilisin, kexin, sedolisin
CPR_2621	ENOG4105E4C	Lytic transglycosylase catalytic
CPR_2635	ENOG4105CBX	hi0933 family
CPR_2638	ENOG4105KY8	Rubrerythrin
CPR_2640	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CPR_2643	ENOG4105EJQ	L-serine dehydratase
CPR_2644	ENOG4105E70	isomerase
CPR_2645	ENOG4105D2N	Aldolase
CPR_2646	ENOG4108X79	transcriptional regulator
CPR_2647	ENOG4105II7	pyrroline-5-carboxylate reductase
CPR_2648	ENOG4105CDU	Replicative dna helicase
CPR_2649	ENOG4108IUQ	atp-dependent protease
CPR_2650	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CPR_2651	ENOG4105BZR	domain protein
CPR_2652	ENOG4108XMW	Membrane
CPR_2654	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CPR_2656	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CPR_2658	ENOG4105D8X	mechanosensitive ion channel
CPR_2661	ENOG4105C9B	Cysteine desulfurase
CPR_2663	ENOG4108ZDA	Sporulation protein YyaC
CPR_2665	ENOG4105FA0	parb-like partition protein
CPR_2666	ENOG4107QJE	Chromosome Partitioning Protein
CPR_2672	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CPR_2673	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CPR_2674	ENOG41087PH	ribosomal protein l34
CPR_A0010	ENOG41071TK	Uncharacterised protein family (UPF0150)
CPR_C0015	ENOG4105CAR	Terminase, large subunit