locus-tag	class	description
Cp267_0003	COG0592	DNA-directed DNA polymerase activity
Cp267_0006	COG0187	DNA topoisomerase II activity
Cp267_0011	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Cp267_0033	COG1120	ATPase activity
Cp267_0034	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_0035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_0036	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Cp267_0038	COG0515	serine threonine protein kinase
Cp267_0038	COG2815	serine threonine protein kinase
Cp267_0039	COG0515	serine threonine protein kinase
Cp267_0040	COG0768	penicillin binding
Cp267_0044	COG1716	ATPase activity
Cp267_0044	COG1716	ATPase activity
Cp267_0049	COG1120	ATPase activity
Cp267_0050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_0051	COG2239	Acts as a magnesium transporter
Cp267_0053	COG0366	Alpha amylase catalytic
Cp267_0066	COG0517	IMP dehydrogenase activity
Cp267_0066	COG1125	glycine betaine transport
Cp267_0068	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Cp267_0072	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Cp267_0074	COG3409	Peptidoglycan-binding domain 1 protein
Cp267_0074	COG3757	hydrolase, family 25
Cp267_0080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Cp267_0085	COG1846	Transcriptional regulator
Cp267_0088	COG3180	Ammonia monooxygenase
Cp267_0090	COG0730	response to heat
Cp267_0093	COG1643	Atp-dependent helicase
Cp267_0094	COG3145	DNA-N1-methyladenine dioxygenase activity
Cp267_0095	COG0519	Catalyzes the synthesis of GMP from XMP
Cp267_0097	COG0393	Putative heavy-metal-binding
Cp267_0098	COG2501	S4 domain
Cp267_0103	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Cp267_0104	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Cp267_0106	COG3590	peptidase
Cp267_0112	COG1028	Short-chain dehydrogenase reductase Sdr
Cp267_0113	COG0277	FAD linked oxidase domain protein
Cp267_0119	COG1216	Glycosyl transferase, family 2
Cp267_0120	COG0803	Belongs to the bacterial solute-binding protein 9 family
Cp267_0121	COG1121	(ABC) transporter
Cp267_0122	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Cp267_0123	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Cp267_0124	COG0803	Belongs to the bacterial solute-binding protein 9 family
Cp267_0129	COG0604	alcohol dehydrogenase
Cp267_0131	COG0471	metal ion transport
Cp267_0137	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Cp267_0140	COG0287	Prephenate dehydrogenase
Cp267_0142	COG0590	tRNA wobble adenosine to inosine editing
Cp267_0143	COG2409	Drug exporters of the RND superfamily
Cp267_0144	COG0343	queuine tRNA-ribosyltransferase activity
Cp267_0146	COG2610	gluconate transmembrane transporter activity
Cp267_0147	COG3265	gluconokinase activity
Cp267_0148	COG1063	alcohol dehydrogenase
Cp267_0149	COG1028	Short-chain dehydrogenase reductase Sdr
Cp267_0151	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Cp267_0156	COG2610	gluconate transmembrane transporter activity
Cp267_0157	COG2084	Dehydrogenase
Cp267_0160	COG0179	Fumarylacetoacetate (FAA) hydrolase
Cp267_0163	COG3442	glutamine amidotransferase
Cp267_0164	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Cp267_0166	COG0778	Nitroreductase
Cp267_0167	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Cp267_0168	COG2390	Transcriptional regulator
Cp267_0169	COG0813	purine-nucleoside phosphorylase activity
Cp267_0172	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Cp267_0178	COG0697	spore germination
Cp267_0179	COG0527	aspartate kinase activity
Cp267_0193	COG1840	ABC-type Fe3 transport system, periplasmic component
Cp267_0194	COG2271	Major facilitator Superfamily
Cp267_0196	COG3852	Histidine kinase
Cp267_0202	COG2111	Na H antiporter
Cp267_0202	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Cp267_0206	COG4152	abc transporter atp-binding protein
Cp267_0214	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Cp267_0219	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Cp267_0223	COG0494	nUDIX hydrolase
Cp267_0237	COG1111	helicase
Cp267_0237	COG1205	dead DEAH box helicase
Cp267_0239	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Cp267_0239	COG1754	DNA topoisomerase type I activity
Cp267_0240	COG1297	OPT oligopeptide transporter protein
Cp267_0242	COG0470	DNA polymerase III
Cp267_0244	COG0318	PFAM AMP-dependent synthetase and ligase
Cp267_0246	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Cp267_0248	COG1088	dTDP-glucose 4,6-dehydratase activity
Cp267_0250	COG1505	serine-type exopeptidase activity
Cp267_0254	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Cp267_0255	COG1396	sequence-specific DNA binding
Cp267_0255	COG3800	Transcriptional regulator
Cp267_0257	COG1053	succinate dehydrogenase
Cp267_0258	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Cp267_0260	COG2733	membrane
Cp267_0262	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Cp267_0266	COG1882	Formate acetyltransferase
Cp267_0270	COG0318	PFAM AMP-dependent synthetase and ligase
Cp267_0273	COG5002	protein histidine kinase activity
Cp267_0274	COG0745	RESPONSE REGULATOR receiver
Cp267_0278	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Cp267_0282	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Cp267_0282	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Cp267_0284	COG0560	Phosphoserine phosphatase
Cp267_0288	COG1648	precorrin-2 dehydrogenase activity
Cp267_0288	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Cp267_0291	COG2217	Heavy metal translocating P-type atpase
Cp267_0296	COG0406	alpha-ribazole phosphatase activity
Cp267_0298	COG0785	Cytochrome C biogenesis protein
Cp267_0300	COG0275	rRNA processing
Cp267_0303	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_0304	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Cp267_0310	COG3069	C4-dicarboxylate transmembrane transporter activity
Cp267_0311	COG4948	Mandelate Racemase Muconate Lactonizing
Cp267_0314	COG0438	transferase activity, transferring glycosyl groups
Cp267_0314	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Cp267_0316	COG0039	L-malate dehydrogenase activity
Cp267_0317	COG0644	oxidoreductase
Cp267_0319	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Cp267_0324	COG3579	cysteine-type endopeptidase activity
Cp267_0325	COG1902	pentaerythritol trinitrate reductase activity
Cp267_0329	COG0803	Belongs to the bacterial solute-binding protein 9 family
Cp267_0331	COG1121	(ABC) transporter
Cp267_0332	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Cp267_0338	COG2197	response regulator
Cp267_0340	COG1131	(ABC) transporter
Cp267_0343	COG0701	Predicted permease
Cp267_0358	COG1302	Protein conserved in bacteria
Cp267_0359	COG0051	transcription antitermination factor activity, RNA binding
Cp267_0380	COG0814	amino acid
Cp267_0381	COG1760	l-serine dehydratase
Cp267_0383	COG0252	asparaginase activity
Cp267_0384	COG0671	phosphoesterase, PA-phosphatase related
Cp267_0393	COG1175	transmembrane transport
Cp267_0394	COG3833	ABC-type maltose transport systems, permease component
Cp267_0398	COG3842	ATPase activity
Cp267_0399	COG0201	protein transport
Cp267_0409	COG0203	ribosomal protein L17
Cp267_0413	COG1404	Belongs to the peptidase S8 family
Cp267_0415	COG1674	ftsk spoiiie
Cp267_0427	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Cp267_0443	COG0516	GMP reductase activity
Cp267_0452	COG2011	ABC-type metal ion transport system permease component
Cp267_0456	COG1464	Belongs to the NlpA lipoprotein family
Cp267_0460	COG0803	Belongs to the bacterial solute-binding protein 9 family
Cp267_0461	COG1121	(ABC) transporter
Cp267_0463	COG1321	iron dependent repressor
Cp267_0463	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Cp267_0464	COG1321	iron dependent repressor
Cp267_0465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Cp267_0466	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Cp267_0473	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_0474	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Cp267_0476	COG2873	o-acetylhomoserine
Cp267_0477	COG2838	Isocitrate dehydrogenase
Cp267_0478	COG2814	Major facilitator Superfamily
Cp267_0479	COG4978	Transcriptional regulator
Cp267_0479	COG0789	Transcriptional regulator
Cp267_0482	COG0180	Tryptophanyl-tRNA synthetase
Cp267_0483	COG1295	ribonuclease BN
Cp267_0484	COG1686	Belongs to the peptidase S11 family
Cp267_0491	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Cp267_0492	COG1473	amidohydrolase
Cp267_0492	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Cp267_0494	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Cp267_0495	COG2814	Major facilitator Superfamily
Cp267_0497	COG4770	biotin carboxylase activity
Cp267_0498	COG2897	thiosulfate sulfurtransferase activity
Cp267_0500	COG0189	ligase activity
Cp267_0501	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Cp267_0501	COG2755	lipolytic protein G-D-S-L family
Cp267_0503	COG0424	maF-like protein
Cp267_0504	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Cp267_0505	COG1609	Transcriptional regulator
Cp267_0507	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Cp267_0508	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Cp267_0510	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Cp267_0510	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Cp267_0521	COG1316	TRANSCRIPTIONal
Cp267_0525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Cp267_0532	COG1482	cell wall glycoprotein biosynthetic process
Cp267_0538	COG0745	RESPONSE REGULATOR receiver
Cp267_0539	COG5002	protein histidine kinase activity
Cp267_0542	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Cp267_0550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Cp267_0551	COG2135	peptidase activity
Cp267_0552	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Cp267_0559	COG0513	Belongs to the DEAD box helicase family
Cp267_0564	COG0210	DNA helicase
Cp267_0566	COG2816	NAD+ diphosphatase activity
Cp267_0571	COG3480	Lon protease (S16) C-terminal proteolytic domain
Cp267_0599	COG0483	inositol monophosphate 1-phosphatase activity
Cp267_0600	COG0483	inositol monophosphate 1-phosphatase activity
Cp267_0603	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Cp267_0605	COG2884	Cell division ATP-binding protein ftsE
Cp267_0606	COG2177	Part of the ABC transporter FtsEX involved in
Cp267_0609	COG0288	reversible hydration of carbon dioxide
Cp267_0617	COG1061	Type III restriction enzyme res subunit
Cp267_0619	COG1652	LysM domain
Cp267_0626	COG2252	PERMEase
Cp267_0627	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Cp267_0632	COG0372	Belongs to the citrate synthase family
Cp267_0633	COG0545	Peptidyl-prolyl cis-trans isomerase
Cp267_0638	COG0656	L-ascorbic acid biosynthetic process
Cp267_0639	COG1024	Enoyl-CoA hydratase
Cp267_0641	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Cp267_0642	COG3757	hydrolase, family 25
Cp267_0646	COG0534	Mate efflux family protein
Cp267_0647	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Cp267_0648	COG0019	diaminopimelate decarboxylase activity
Cp267_0651	COG4166	transmembrane transport
Cp267_0662	COG1218	3'(2'),5'-bisphosphate nucleotidase
Cp267_0664	COG1201	RNA secondary structure unwinding
Cp267_0666	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Cp267_0672	COG0739	heme binding
Cp267_0677	COG1126	abc transporter atp-binding protein
Cp267_0678	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Cp267_0679	COG0765	amino acid transport
Cp267_0680	COG0765	amino acid transport
Cp267_0688	COG0254	rRNA binding
Cp267_0690	COG0745	RESPONSE REGULATOR receiver
Cp267_0691	COG2205	protein histidine kinase activity
Cp267_0692	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Cp267_0693	COG0315	cyclic pyranopterin monophosphate synthase activity
Cp267_0693	COG0521	Mo-molybdopterin cofactor biosynthetic process
Cp267_0698	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Cp267_0702	COG2259	Doxx family
Cp267_0704	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
Cp267_0706	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Cp267_0707	COG3949	Membrane
Cp267_0710	COG0084	hydrolase, TatD family'
Cp267_0711	COG3583	domain protein
Cp267_0714	COG0488	(ABC) transporter
Cp267_0717	COG2326	polyphosphate kinase activity
Cp267_0719	COG0561	phosphatase activity
Cp267_0728	COG0596	Alpha beta hydrolase
Cp267_0729	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Cp267_0731	COG0193	aminoacyl-tRNA hydrolase activity
Cp267_0732	COG2070	2-Nitropropane dioxygenase
Cp267_0736	COG1523	belongs to the glycosyl hydrolase 13 family
Cp267_0737	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Cp267_0738	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Cp267_0739	COG2132	Multicopper oxidase
Cp267_0741	COG1309	transcriptional regulator
Cp267_0744	COG0531	amino acid
Cp267_0745	COG3956	TIGRFAM MazG family protein
Cp267_0757	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Cp267_0771	COG0114	fumarate hydratase activity
Cp267_0772	COG1494	fructose-1,6-bisphosphatase
Cp267_0779	COG0012	GTP binding
Cp267_0782	COG2824	Alkylphosphonate utilization operon protein PhnA
Cp267_0783	COG1132	(ABC) transporter
Cp267_0785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Cp267_0786	COG2354	Protein conserved in bacteria
Cp267_0788	COG4721	ABC-type cobalt transport system, permease component
Cp267_0789	COG1122	ATPase activity
Cp267_0791	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Cp267_0793	COG4166	transmembrane transport
Cp267_0794	COG0601	transmembrane transport
Cp267_0797	COG5640	endopeptidase activity
Cp267_0802	COG4166	transmembrane transport
Cp267_0809	COG1113	amino acid transport
Cp267_0811	COG1113	amino acid transport
Cp267_0813	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Cp267_0814	COG1611	Belongs to the LOG family
Cp267_0815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Cp267_0816	COG0463	Glycosyl transferase, family 2
Cp267_0821	COG3527	Alpha-acetolactate decarboxylase
Cp267_0822	COG0297	glycogen (starch) synthase activity
Cp267_0824	COG4122	O-methyltransferase activity
Cp267_0830	COG2239	Acts as a magnesium transporter
Cp267_0832	COG0567	Dehydrogenase, E1 component
Cp267_0832	COG0508	dehydrogenase complex catalyzes the overall conversion of
Cp267_0833	COG1132	(ABC) transporter
Cp267_0835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Cp267_0836	COG2272	Belongs to the type-B carboxylesterase lipase family
Cp267_0840	COG2017	converts alpha-aldose to the beta-anomer
Cp267_0844	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Cp267_0850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Cp267_0851	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Cp267_0856	COG1846	Transcriptional regulator
Cp267_0859	COG1349	DNA-binding transcription factor activity
Cp267_0861	COG1556	Lactate utilization protein
Cp267_0862	COG1139	Iron-sulfur cluster binding protein
Cp267_0863	COG0247	lactate metabolic process
Cp267_0864	COG1620	l-lactate permease
Cp267_0866	COG0019	diaminopimelate decarboxylase activity
Cp267_0867	COG0460	homoserine dehydrogenase
Cp267_0878	COG0356	it plays a direct role in the translocation of protons across the membrane
Cp267_0879	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Cp267_0880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Cp267_0894	COG1119	ATPase activity
Cp267_0898	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Cp267_0912	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_0913	COG1120	ATPase activity
Cp267_0915	COG0205	6-phosphofructokinase activity
Cp267_0917	COG0667	Aldo Keto reductase
Cp267_0919	COG0583	DNA-binding transcription factor activity
Cp267_0925	COG0668	transmembrane transport
Cp267_0933	COG0473	3-isopropylmalate dehydrogenase activity
Cp267_0937	COG0179	Fumarylacetoacetate (FAA) hydrolase
Cp267_0955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Cp267_0956	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Cp267_0957	COG1461	Dihydroxyacetone kinase
Cp267_0959	COG0511	ligase activity, forming carbon-carbon bonds
Cp267_0960	COG0742	ribosomal rna small subunit methyltransferase
Cp267_0965	COG0765	amino acid transport
Cp267_0971	COG0539	negative regulation of cytoplasmic translation
Cp267_0974	COG0237	dephospho-CoA kinase activity
Cp267_0978	COG3973	AAA domain
Cp267_0981	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Cp267_0984	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Cp267_0987	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Cp267_0990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Cp267_0993	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Cp267_0997	COG0165	Argininosuccinate lyase
Cp267_0998	COG2835	tetraacyldisaccharide 4'-kinase activity
Cp267_1002	COG0647	UMP catabolic process
Cp267_1010	COG4974	Belongs to the 'phage' integrase family
Cp267_1015	COG3104	oligopeptide transport
Cp267_1016	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Cp267_1018	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Cp267_1021	COG1160	GTP binding
Cp267_1022	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Cp267_1024	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Cp267_1025	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Cp267_1026	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Cp267_1027	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_1028	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_1029	COG1120	ATPase activity
Cp267_1030	COG4264	IucA IucC family
Cp267_1034	COG3547	Transposase (IS116 IS110 IS902 family)
Cp267_1040	COG3012	SEC-C Motif Domain Protein
Cp267_1043	COG0653	protein targeting
Cp267_1051	COG1253	flavin adenine dinucleotide binding
Cp267_1052	COG0513	Belongs to the DEAD box helicase family
Cp267_1053	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Cp267_1055	COG0598	Magnesium transport protein CorA
Cp267_1059	COG0477	Major facilitator Superfamily
Cp267_1064	COG0463	Glycosyl transferase, family 2
Cp267_1074	COG0300	oxidoreductase activity
Cp267_1077	COG0805	protein transport
Cp267_1079	COG2378	regulation of single-species biofilm formation
Cp267_1083	COG4122	O-methyltransferase activity
Cp267_1086	COG1362	aminopeptidase activity
Cp267_1091	COG1027	Aspartate ammonia-lyase
Cp267_1093	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Cp267_1098	COG0646	methionine synthase
Cp267_1098	COG1410	methionine synthase
Cp267_1102	COG0667	Aldo Keto reductase
Cp267_1104	COG0167	dihydroorotate dehydrogenase activity
Cp267_1109	COG1461	Dihydroxyacetone kinase
Cp267_1110	COG2376	Dihydroxyacetone kinase
Cp267_1125	COG0791	NLP P60 protein
Cp267_1125	COG3883	PFAM NLP P60 protein
Cp267_1131	COG2848	UPF0210 protein
Cp267_1137	COG2151	metal-sulfur cluster biosynthetic enzyme
Cp267_1138	COG0822	iron-sulfur transferase activity
Cp267_1140	COG0396	ATPase activity
Cp267_1149	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Cp267_1150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Cp267_1154	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Cp267_1158	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Cp267_1160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Cp267_1162	COG0322	excinuclease ABC activity
Cp267_1168	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Cp267_1171	COG0242	peptide deformylase activity
Cp267_1180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Cp267_1182	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Cp267_1185	COG1090	epimerase
Cp267_1190	COG0006	proline dipeptidase activity
Cp267_1191	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Cp267_1192	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Cp267_1193	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Cp267_1194	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Cp267_1198	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Cp267_1210	COG1760	l-serine dehydratase
Cp267_1216	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Cp267_1217	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Cp267_1221	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Cp267_1224	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Cp267_1225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Cp267_1232	COG1946	Acyl-CoA thioesterase
Cp267_1235	COG0156	8-amino-7-oxononanoate synthase activity
Cp267_1238	COG1560	Kdo2-lipid A biosynthetic process
Cp267_1242	COG2837	iron assimilation
Cp267_1249	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Cp267_1268	COG2890	protein-(glutamine-N5) methyltransferase activity
Cp267_1276	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Cp267_1277	COG0450	alkyl hydroperoxide reductase
Cp267_1281	COG1643	Atp-dependent helicase
Cp267_1286	COG1349	DNA-binding transcription factor activity
Cp267_1287	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Cp267_1288	COG1349	DNA-binding transcription factor activity
Cp267_1289	COG1105	Belongs to the carbohydrate kinase PfkB family
Cp267_1290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Cp267_1290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Cp267_1290	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Cp267_1292	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Cp267_1293	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Cp267_1295	COG2233	PERMEase
Cp267_1296	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Cp267_1299	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Cp267_1302	COG1196	nuclear chromosome segregation
Cp267_1306	COG2137	regulation of response to DNA damage stimulus
Cp267_1307	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Cp267_1309	COG1268	BioY protein
Cp267_1310	COG1122	ATPase activity
Cp267_1313	COG1396	sequence-specific DNA binding
Cp267_1317	COG0861	Integral membrane protein TerC family
Cp267_1320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Cp267_1328	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Cp267_1331	COG0534	Mate efflux family protein
Cp267_1340	COG3022	response to hydroperoxide
Cp267_1341	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Cp267_1341	COG1648	precorrin-2 dehydrogenase activity
Cp267_1342	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Cp267_1343	COG0523	cobalamin synthesis protein
Cp267_1344	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Cp267_1344	COG2169	Transcriptional regulator
Cp267_1357	COG0750	zinc metalloprotease
Cp267_1369	COG4974	Belongs to the 'phage' integrase family
Cp267_1371	COG0606	chelatase, subunit chli
Cp267_1377	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Cp267_1377	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Cp267_1377	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Cp267_1379	COG0336	Belongs to the RNA methyltransferase TrmD family
Cp267_1380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Cp267_1384	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Cp267_1390	COG1115	amino acid carrier protein
Cp267_1391	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Cp267_1396	COG0686	Belongs to the AlaDH PNT family
Cp267_1397	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Cp267_1398	COG1929	Belongs to the glycerate kinase type-1 family
Cp267_1401	COG1473	amidohydrolase
Cp267_1402	COG0058	SHG alpha-glucan phosphorylase activity
Cp267_1404	COG0469	pyruvate kinase activity
Cp267_1406	COG0134	indole-3-glycerol-phosphate synthase activity
Cp267_1410	COG0483	inositol monophosphate 1-phosphatase activity
Cp267_1423	COG2176	DNA-directed DNA polymerase activity
Cp267_1429	COG1739	Uncharacterized protein family UPF0029
Cp267_1430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Cp267_1435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Cp267_1438	COG0252	asparaginase activity
Cp267_1442	COG3599	regulation of cell shape
Cp267_1444	COG1799	cell septum assembly
Cp267_1447	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Cp267_1449	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Cp267_1456	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Cp267_1457	COG0768	penicillin binding
Cp267_1470	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Cp267_1474	COG1940	carbohydrate kinase activity
Cp267_1475	COG0438	transferase activity, transferring glycosyl groups
Cp267_1477	COG0791	NLP P60 protein
Cp267_1489	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
Cp267_1490	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Cp267_1492	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Cp267_1495	COG0508	dehydrogenase complex catalyzes the overall conversion of
Cp267_1496	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Cp267_1496	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Cp267_1497	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Cp267_1498	COG0509	glycine decarboxylation via glycine cleavage system
Cp267_1537	COG2056	Na+-H+ antiporter family
Cp267_1540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Cp267_1545	COG0174	glutamine synthetase
Cp267_1550	COG0557	exoribonuclease II activity
Cp267_1552	COG0328	RNA-DNA hybrid ribonuclease activity
Cp267_1552	COG0406	alpha-ribazole phosphatase activity
Cp267_1554	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Cp267_1554	COG3323	Protein of unknown function (DUF1653)
Cp267_1562	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Cp267_1568	COG2860	membrane
Cp267_1580	COG0423	glycine-tRNA ligase activity
Cp267_1586	COG1381	Involved in DNA repair and RecF pathway recombination
Cp267_1597	COG1022	Amp-dependent synthetase and ligase
Cp267_1607	COG1132	(ABC) transporter
Cp267_1608	COG1114	Component of the transport system for branched-chain amino acids
Cp267_1609	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Cp267_1611	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Cp267_1614	COG0747	negative chemotaxis
Cp267_1615	COG0601	transmembrane transport
Cp267_1616	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Cp267_1617	COG4172	Belongs to the ABC transporter superfamily
Cp267_1620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Cp267_1621	COG2391	methyltransferase activity
Cp267_1625	COG4171	peptide transport system, permease
Cp267_1627	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Cp267_1628	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Cp267_1633	COG1280	lysine exporter protein (LysE YggA)
Cp267_1638	COG1307	EDD domain protein, DegV family
Cp267_1639	COG0406	alpha-ribazole phosphatase activity
Cp267_1641	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Cp267_1644	COG2832	Protein of unknown function (DUF454)
Cp267_1645	COG2985	domain, Protein
Cp267_1645	COG0569	domain protein
Cp267_1650	COG1530	ribonuclease E activity
Cp267_1654	COG2423	ornithine cyclodeaminase activity
Cp267_1656	COG0285	dihydrofolate synthase activity
Cp267_1665	COG0544	peptidyl-prolyl cis-trans isomerase activity
Cp267_1671	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Cp267_1675	COG0668	transmembrane transport
Cp267_1691	COG1131	(ABC) transporter
Cp267_1692	COG3336	cytochrome c oxidase
Cp267_1695	COG1966	Carbon starvation protein
Cp267_1699	COG0604	alcohol dehydrogenase
Cp267_1700	COG4221	oxidoreductase activity
Cp267_1703	COG1376	ErfK ybiS ycfS ynhG family protein
Cp267_1704	COG2130	NADP-dependent
Cp267_1705	COG1335	isochorismatase
Cp267_1714	COG2197	response regulator
Cp267_1723	COG1234	tRNA 3'-trailer cleavage
Cp267_1728	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Cp267_1738	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Cp267_1741	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Cp267_1745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Cp267_1758	COG0033	Phosphoglucomutase
Cp267_1761	COG0577	efflux transmembrane transporter activity
Cp267_1761	COG1136	(ABC) transporter
Cp267_1762	COG0577	efflux transmembrane transporter activity
Cp267_1762	COG1136	(ABC) transporter
Cp267_1766	COG2197	response regulator
Cp267_1769	COG1045	serine acetyltransferase
Cp267_1772	COG1271	oxidase subunit
Cp267_1773	COG1294	oxidase, subunit
Cp267_1774	COG4988	ABC transporter
Cp267_1775	COG4988	ABC transporter
Cp267_1780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Cp267_1786	COG1597	lipid kinase activity
Cp267_1789	COG0354	folic acid binding
Cp267_1794	COG1780	Probably involved in ribonucleotide reductase function
Cp267_1795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Cp267_1797	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Cp267_1798	COG0047	phosphoribosylformylglycinamidine synthase activity
Cp267_1799	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Cp267_1800	COG0386	Belongs to the glutathione peroxidase family
Cp267_1804	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Cp267_1805	COG0569	domain protein
Cp267_1806	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Cp267_1807	COG0151	Belongs to the GarS family
Cp267_1808	COG0537	adenosine 5'-monophosphoramidase activity
Cp267_1810	COG2205	protein histidine kinase activity
Cp267_1811	COG0745	RESPONSE REGULATOR receiver
Cp267_1817	COG0028	Belongs to the TPP enzyme family
Cp267_1825	COG1609	Transcriptional regulator
Cp267_1827	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Cp267_1831	COG1329	Transcriptional regulator
Cp267_1832	COG2847	Copper chaperone PCu(A)C
Cp267_1835	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Cp267_1837	COG0288	reversible hydration of carbon dioxide
Cp267_1841	COG0542	response to heat
Cp267_1843	COG0477	Major facilitator Superfamily
Cp267_1844	COG1957	nucleoside hydrolase
Cp267_1847	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Cp267_1850	COG1301	dicarboxylic acid transport
Cp267_1852	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Cp267_1853	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Cp267_1854	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Cp267_1859	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Cp267_1861	COG0302	gtp cyclohydrolase
Cp267_1862	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Cp267_1866	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Cp267_1867	COG0425	Belongs to the sulfur carrier protein TusA family
Cp267_1867	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Cp267_1868	COG1301	dicarboxylic acid transport
Cp267_1872	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Cp267_1874	COG2326	polyphosphate kinase activity
Cp267_1878	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Cp267_1883	COG2111	Na H antiporter
Cp267_1883	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Cp267_1889	COG1051	belongs to the nudix hydrolase family
Cp267_1893	COG0242	peptide deformylase activity
Cp267_1894	COG0456	acetyltransferase
Cp267_1895	COG0708	Exodeoxyribonuclease III
Cp267_1896	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Cp267_1901	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Cp267_1904	COG0280	phosphate acetyltransferase
Cp267_1908	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Cp267_1909	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Cp267_1916	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Cp267_1917	COG1333	cytochrome c biogenesis protein
Cp267_1919	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Cp267_1920	COG3005	denitrification pathway
Cp267_1923	COG4129	membrane
Cp267_1925	COG4129	membrane
Cp267_1932	COG0191	fructose-bisphosphate aldolase activity
Cp267_1935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Cp267_1938	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Cp267_1948	COG1131	(ABC) transporter
Cp267_1957	COG1136	(ABC) transporter
Cp267_1957	COG0577	efflux transmembrane transporter activity
Cp267_1958	COG1136	(ABC) transporter
Cp267_1959	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Cp267_1964	COG1012	belongs to the aldehyde dehydrogenase family
Cp267_1967	COG0789	Transcriptional regulator
Cp267_1970	COG0443	Heat shock 70 kDa protein
Cp267_1978	COG0601	transmembrane transport
Cp267_1983	COG2181	nitrate reductase activity
Cp267_1983	COG0247	lactate metabolic process
Cp267_1986	COG1120	ATPase activity
Cp267_1987	COG4139	cobalamin transport
Cp267_1989	COG0829	nickel cation binding
Cp267_1990	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Cp267_1991	COG0830	nickel cation binding
Cp267_1992	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Cp267_1993	COG0804	urea catabolic process
Cp267_1994	COG0832	Belongs to the urease beta subunit family
Cp267_1995	COG0831	urea catabolic process
Cp267_2000	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Cp267_2000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Cp267_2004	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Cp267_2006	COG1012	belongs to the aldehyde dehydrogenase family
Cp267_2008	COG1472	Belongs to the glycosyl hydrolase 3 family
Cp267_2010	COG4981	capsule polysaccharide biosynthetic process
Cp267_2011	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Cp267_2011	COG2755	lipolytic protein G-D-S-L family
Cp267_2015	COG0500	methyltransferase
Cp267_2024	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Cp267_2025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Cp267_2025	COG3321	synthase
Cp267_2026	COG0318	PFAM AMP-dependent synthetase and ligase
Cp267_2029	COG5479	isomerase activity
Cp267_2029	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Cp267_2032	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Cp267_2033	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Cp267_2034	COG0671	phosphoesterase, PA-phosphatase related
Cp267_2035	COG1216	Glycosyl transferase, family 2
Cp267_2037	COG0671	phosphoesterase, PA-phosphatase related
Cp267_2039	COG0584	glycerophosphoryl diester phosphodiesterase
Cp267_2043	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Cp267_2044	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Cp267_2047	COG0561	phosphatase activity
Cp267_2050	COG2188	Transcriptional regulator
Cp267_2054	COG0077	Prephenate dehydratase
Cp267_2055	COG0154	amidase activity
Cp267_2057	COG1316	TRANSCRIPTIONal
Cp267_2063	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Cp267_2069	COG0431	NADPH-dependent FMN reductase
Cp267_2070	COG2814	Major facilitator Superfamily
Cp267_2073	COG2271	Major facilitator Superfamily
Cp267_2075	COG5650	phosphatidylinositol metabolic process
Cp267_2079	COG2197	response regulator
Cp267_2083	COG3764	Sortase (surface protein transpeptidase)
Cp267_2084	COG0706	membrane insertase activity
Cp267_2090	COG0564	pseudouridine synthase activity
Cp267_2093	COG1131	(ABC) transporter
Cp267_2097	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Cp267_2100	COG0477	Major facilitator Superfamily
Cp267_2101	COG0305	Participates in initiation and elongation during chromosome replication
Cp267_2102	COG3387	PFAM Glycoside hydrolase 15-related
Cp267_2106	COG0629	single-stranded DNA binding
Cp267_2112	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Cp267_2116	COG0300	oxidoreductase activity
Cp267_2119	COG0586	Pfam SNARE associated Golgi protein
Cp267_2120	COG0783	Belongs to the Dps family
Cp267_2121	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Cp267_2122	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Cp267_2122	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Cp267_2124	COG1511	domain protein
Cp267_2129	COG1136	(ABC) transporter
Cp267_2129	COG0577	efflux transmembrane transporter activity
Cp267_2133	COG4585	Histidine kinase
Cp267_2134	COG2197	response regulator
Cp267_2137	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Cp267_2140	COG2186	Transcriptional regulator
Cp267_2141	COG0747	negative chemotaxis
Cp267_2142	COG0601	transmembrane transport
Cp267_2143	COG0444	Belongs to the ABC transporter superfamily
Cp267_2144	COG4608	Belongs to the ABC transporter superfamily
Cp267_2145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Cp267_2153	COG3422	double-strand break repair
Cp267_2156	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Cp267_2160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Cp267_2161	COG0512	Glutamine amidotransferase of anthranilate synthase
Cp267_2163	COG0135	phosphoribosylanthranilate isomerase activity
Cp267_2163	COG0134	indole-3-glycerol-phosphate synthase activity
Cp267_2169	COG1687	branched-chain amino acid
Cp267_2171	COG1678	Uncharacterized ACR, COG1678
Cp267_2172	COG0617	tRNA 3'-terminal CCA addition
Cp267_2180	COG0860	N-Acetylmuramoyl-L-alanine amidase
Cp267_2180	COG3409	Peptidoglycan-binding domain 1 protein
Cp267_2183	COG1192	Involved in chromosome partitioning
Cp267_2186	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Cp267_2188	COG0230	Belongs to the bacterial ribosomal protein bL34 family