locus-tag	class	description
CP162_00015	COG0592	DNA-directed DNA polymerase activity
CP162_00030	COG0187	DNA topoisomerase II activity
CP162_00050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP162_00155	COG1518	maintenance of DNA repeat elements
CP162_00200	COG1120	ATPase activity
CP162_00205	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_00210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_00215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP162_00225	COG0515	serine threonine protein kinase
CP162_00225	COG2815	serine threonine protein kinase
CP162_00230	COG0515	serine threonine protein kinase
CP162_00235	COG0768	penicillin binding
CP162_00255	COG1716	ATPase activity
CP162_00255	COG1716	ATPase activity
CP162_00285	COG1120	ATPase activity
CP162_00290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_00295	COG2239	Acts as a magnesium transporter
CP162_00300	COG0366	Alpha amylase catalytic
CP162_00355	COG0517	IMP dehydrogenase activity
CP162_00355	COG1125	glycine betaine transport
CP162_00390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP162_00425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CP162_00455	COG1846	Transcriptional regulator
CP162_00490	COG0730	response to heat
CP162_00505	COG1643	Atp-dependent helicase
CP162_00515	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_00520	COG0519	Catalyzes the synthesis of GMP from XMP
CP162_00530	COG0393	Putative heavy-metal-binding
CP162_00535	COG2501	S4 domain
CP162_00560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP162_00565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP162_00575	COG3590	peptidase
CP162_00605	COG1028	Short-chain dehydrogenase reductase Sdr
CP162_00610	COG0277	FAD linked oxidase domain protein
CP162_00640	COG1216	Glycosyl transferase, family 2
CP162_00645	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP162_00650	COG1121	(ABC) transporter
CP162_00655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP162_00660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP162_00665	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP162_00690	COG0604	alcohol dehydrogenase
CP162_00725	COG0393	Putative heavy-metal-binding
CP162_00760	COG1263	PTS System
CP162_00760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP162_00765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP162_00765	COG2190	(PTS) system
CP162_00765	COG1263	PTS System
CP162_00790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP162_00805	COG0287	Prephenate dehydrogenase
CP162_00825	COG2409	Drug exporters of the RND superfamily
CP162_00830	COG0343	queuine tRNA-ribosyltransferase activity
CP162_00840	COG2610	gluconate transmembrane transporter activity
CP162_00845	COG3265	gluconokinase activity
CP162_00850	COG1063	alcohol dehydrogenase
CP162_00855	COG1028	Short-chain dehydrogenase reductase Sdr
CP162_00870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP162_00895	COG2610	gluconate transmembrane transporter activity
CP162_00900	COG2084	Dehydrogenase
CP162_00915	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP162_00925	COG3442	glutamine amidotransferase
CP162_00930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP162_00940	COG0778	Nitroreductase
CP162_00945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP162_00950	COG2390	Transcriptional regulator
CP162_00955	COG0813	purine-nucleoside phosphorylase activity
CP162_00970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP162_00995	COG0697	spore germination
CP162_01000	COG0527	aspartate kinase activity
CP162_01055	COG1840	ABC-type Fe3 transport system, periplasmic component
CP162_01060	COG2271	Major facilitator Superfamily
CP162_01100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP162_01100	COG2111	Na H antiporter
CP162_01130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP162_01155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP162_01175	COG0494	nUDIX hydrolase
CP162_01245	COG1205	dead DEAH box helicase
CP162_01245	COG1111	helicase
CP162_01255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP162_01255	COG1754	DNA topoisomerase type I activity
CP162_01260	COG1297	OPT oligopeptide transporter protein
CP162_01270	COG0470	DNA polymerase III
CP162_01285	COG0318	PFAM AMP-dependent synthetase and ligase
CP162_01295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CP162_01305	COG1088	dTDP-glucose 4,6-dehydratase activity
CP162_01315	COG1505	serine-type exopeptidase activity
CP162_01330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP162_01335	COG3800	Transcriptional regulator
CP162_01335	COG1396	sequence-specific DNA binding
CP162_01345	COG1053	succinate dehydrogenase
CP162_01350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP162_01360	COG2733	membrane
CP162_01370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CP162_01390	COG1882	Formate acetyltransferase
CP162_01410	COG0318	PFAM AMP-dependent synthetase and ligase
CP162_01425	COG5002	protein histidine kinase activity
CP162_01430	COG0745	RESPONSE REGULATOR receiver
CP162_01450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP162_01470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP162_01470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP162_01500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP162_01500	COG1648	precorrin-2 dehydrogenase activity
CP162_01515	COG2217	Heavy metal translocating P-type atpase
CP162_01540	COG0406	alpha-ribazole phosphatase activity
CP162_01550	COG0785	Cytochrome C biogenesis protein
CP162_01560	COG0275	rRNA processing
CP162_01575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_01580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP162_01615	COG4948	Mandelate Racemase Muconate Lactonizing
CP162_01640	COG0039	L-malate dehydrogenase activity
CP162_01645	COG0644	oxidoreductase
CP162_01675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP162_01700	COG3579	cysteine-type endopeptidase activity
CP162_01705	COG1902	pentaerythritol trinitrate reductase activity
CP162_01725	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP162_01735	COG1121	(ABC) transporter
CP162_01740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP162_01770	COG2197	response regulator
CP162_01775	COG1131	(ABC) transporter
CP162_01790	COG0701	Predicted permease
CP162_01860	COG1302	Protein conserved in bacteria
CP162_01955	COG0814	amino acid
CP162_01960	COG1760	l-serine dehydratase
CP162_01965	COG0252	asparaginase activity
CP162_02005	COG1140	nitrate reductase beta subunit
CP162_02035	COG0315	cyclic pyranopterin monophosphate synthase activity
CP162_02045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP162_02095	COG1175	transmembrane transport
CP162_02100	COG3833	ABC-type maltose transport systems, permease component
CP162_02125	COG0201	protein transport
CP162_02180	COG0203	ribosomal protein L17
CP162_02200	COG1404	Belongs to the peptidase S8 family
CP162_02210	COG1674	ftsk spoiiie
CP162_02265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP162_02340	COG0516	GMP reductase activity
CP162_02385	COG2011	ABC-type metal ion transport system permease component
CP162_02395	COG1464	Belongs to the NlpA lipoprotein family
CP162_02405	COG1464	Belongs to the NlpA lipoprotein family
CP162_02410	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_02420	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP162_02425	COG1121	(ABC) transporter
CP162_02435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP162_02435	COG1321	iron dependent repressor
CP162_02440	COG1321	iron dependent repressor
CP162_02445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CP162_02450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP162_02490	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP162_02500	COG2873	o-acetylhomoserine
CP162_02505	COG2838	Isocitrate dehydrogenase
CP162_02510	COG2814	Major facilitator Superfamily
CP162_02515	COG0789	Transcriptional regulator
CP162_02515	COG4978	Transcriptional regulator
CP162_02530	COG0180	Tryptophanyl-tRNA synthetase
CP162_02535	COG1295	ribonuclease BN
CP162_02540	COG1686	Belongs to the peptidase S11 family
CP162_02575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP162_02580	COG1473	amidohydrolase
CP162_02580	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP162_02595	COG2814	Major facilitator Superfamily
CP162_02605	COG4770	biotin carboxylase activity
CP162_02610	COG2897	thiosulfate sulfurtransferase activity
CP162_02615	COG0189	ligase activity
CP162_02620	COG2755	lipolytic protein G-D-S-L family
CP162_02620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP162_02630	COG0424	maF-like protein
CP162_02635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP162_02640	COG1609	Transcriptional regulator
CP162_02650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP162_02655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP162_02660	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CP162_02660	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CP162_02710	COG1316	TRANSCRIPTIONal
CP162_02720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP162_02755	COG1482	cell wall glycoprotein biosynthetic process
CP162_02760	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_02785	COG0745	RESPONSE REGULATOR receiver
CP162_02790	COG5002	protein histidine kinase activity
CP162_02805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP162_02845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP162_02850	COG2135	peptidase activity
CP162_02855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP162_02925	COG2816	NAD+ diphosphatase activity
CP162_02950	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP162_03015	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_03020	COG1652	LysM domain
CP162_03045	COG2252	PERMEase
CP162_03050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP162_03070	COG0372	Belongs to the citrate synthase family
CP162_03075	COG0545	Peptidyl-prolyl cis-trans isomerase
CP162_03090	COG0656	L-ascorbic acid biosynthetic process
CP162_03095	COG1024	Enoyl-CoA hydratase
CP162_03105	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP162_03115	COG3757	hydrolase, family 25
CP162_03135	COG0534	Mate efflux family protein
CP162_03140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP162_03145	COG0019	diaminopimelate decarboxylase activity
CP162_03160	COG4166	transmembrane transport
CP162_03175	COG4172	Belongs to the ABC transporter superfamily
CP162_03200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CP162_03215	COG1218	3'(2'),5'-bisphosphate nucleotidase
CP162_03260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP162_03310	COG1126	abc transporter atp-binding protein
CP162_03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP162_03320	COG0765	amino acid transport
CP162_03325	COG0765	amino acid transport
CP162_03365	COG0254	rRNA binding
CP162_03375	COG0745	RESPONSE REGULATOR receiver
CP162_03380	COG2205	protein histidine kinase activity
CP162_03385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP162_03390	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP162_03390	COG0315	cyclic pyranopterin monophosphate synthase activity
CP162_03415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP162_03435	COG2259	Doxx family
CP162_03445	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CP162_03455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP162_03460	COG3949	Membrane
CP162_03475	COG0084	hydrolase, TatD family'
CP162_03480	COG3583	domain protein
CP162_03495	COG0488	(ABC) transporter
CP162_03510	COG2326	polyphosphate kinase activity
CP162_03520	COG0561	phosphatase activity
CP162_03550	COG0596	Alpha beta hydrolase
CP162_03555	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CP162_03565	COG0193	aminoacyl-tRNA hydrolase activity
CP162_03570	COG2070	2-Nitropropane dioxygenase
CP162_03590	COG1523	belongs to the glycosyl hydrolase 13 family
CP162_03595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP162_03600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP162_03605	COG2132	Multicopper oxidase
CP162_03615	COG1309	transcriptional regulator
CP162_03625	COG0531	amino acid
CP162_03630	COG3956	TIGRFAM MazG family protein
CP162_03690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP162_03760	COG0114	fumarate hydratase activity
CP162_03765	COG1494	fructose-1,6-bisphosphatase
CP162_03790	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_03795	COG2056	Na+-H+ antiporter family
CP162_03840	COG0174	glutamine synthetase
CP162_03870	COG0509	glycine decarboxylation via glycine cleavage system
CP162_03875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP162_03880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP162_03880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP162_03885	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP162_03900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP162_03910	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP162_03915	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CP162_03965	COG0791	NLP P60 protein
CP162_03975	COG0438	transferase activity, transferring glycosyl groups
CP162_03980	COG1940	carbohydrate kinase activity
CP162_04000	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP162_04065	COG0768	penicillin binding
CP162_04070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP162_04100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP162_04110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP162_04120	COG1799	cell septum assembly
CP162_04130	COG3599	regulation of cell shape
CP162_04150	COG0252	asparaginase activity
CP162_04165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP162_04195	COG1739	Uncharacterized protein family UPF0029
CP162_04220	COG2176	DNA-directed DNA polymerase activity
CP162_04285	COG0483	inositol monophosphate 1-phosphatase activity
CP162_04305	COG0134	indole-3-glycerol-phosphate synthase activity
CP162_04315	COG0469	pyruvate kinase activity
CP162_04325	COG0058	SHG alpha-glucan phosphorylase activity
CP162_04335	COG1473	amidohydrolase
CP162_04350	COG1929	Belongs to the glycerate kinase type-1 family
CP162_04355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP162_04360	COG0686	Belongs to the AlaDH PNT family
CP162_04385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP162_04390	COG1115	amino acid carrier protein
CP162_04395	COG1254	Belongs to the acylphosphatase family
CP162_04420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP162_04440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP162_04445	COG0336	Belongs to the RNA methyltransferase TrmD family
CP162_04455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP162_04455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP162_04455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP162_04470	COG0681	Belongs to the peptidase S26 family
CP162_04500	COG4974	Belongs to the 'phage' integrase family
CP162_04545	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_04560	COG0750	zinc metalloprotease
CP162_04625	COG2169	Transcriptional regulator
CP162_04625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP162_04630	COG0523	cobalamin synthesis protein
CP162_04640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP162_04640	COG1648	precorrin-2 dehydrogenase activity
CP162_04645	COG3022	response to hydroperoxide
CP162_04690	COG0534	Mate efflux family protein
CP162_04705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP162_04745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP162_04755	COG1674	ftsk spoiiie
CP162_04780	COG1396	sequence-specific DNA binding
CP162_04795	COG1122	ATPase activity
CP162_04800	COG1268	BioY protein
CP162_04810	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP162_04815	COG2137	regulation of response to DNA damage stimulus
CP162_04835	COG1196	nuclear chromosome segregation
CP162_04850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP162_04865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP162_04870	COG2233	PERMEase
CP162_04880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP162_04885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP162_04900	COG1105	Belongs to the carbohydrate kinase PfkB family
CP162_04905	COG1349	DNA-binding transcription factor activity
CP162_04910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP162_04915	COG1349	DNA-binding transcription factor activity
CP162_04940	COG1643	Atp-dependent helicase
CP162_04955	COG0450	alkyl hydroperoxide reductase
CP162_04960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP162_05000	COG2890	protein-(glutamine-N5) methyltransferase activity
CP162_05090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP162_05145	COG2837	iron assimilation
CP162_05160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP162_05165	COG1560	Kdo2-lipid A biosynthetic process
CP162_05180	COG0156	8-amino-7-oxononanoate synthase activity
CP162_05225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP162_05230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP162_05245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP162_05260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CP162_05265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP162_05290	COG1760	l-serine dehydratase
CP162_05345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP162_05350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP162_05365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP162_05370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP162_05375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP162_05380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP162_05385	COG0006	proline dipeptidase activity
CP162_05410	COG1090	epimerase
CP162_05425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP162_05435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP162_05480	COG0242	peptide deformylase activity
CP162_05495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP162_05525	COG0322	excinuclease ABC activity
CP162_05535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP162_05545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP162_05565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP162_05585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP162_05590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP162_05635	COG0396	ATPase activity
CP162_05645	COG0822	iron-sulfur transferase activity
CP162_05650	COG2151	metal-sulfur cluster biosynthetic enzyme
CP162_05655	COG0488	(ABC) transporter
CP162_05675	COG2848	UPF0210 protein
CP162_05705	COG0791	NLP P60 protein
CP162_05705	COG3883	PFAM NLP P60 protein
CP162_05780	COG2376	Dihydroxyacetone kinase
CP162_05785	COG1461	Dihydroxyacetone kinase
CP162_05810	COG0167	dihydroorotate dehydrogenase activity
CP162_05820	COG0667	Aldo Keto reductase
CP162_05840	COG0646	methionine synthase
CP162_05840	COG1410	methionine synthase
CP162_05865	COG1027	Aspartate ammonia-lyase
CP162_05885	COG1362	aminopeptidase activity
CP162_05900	COG4122	O-methyltransferase activity
CP162_05920	COG2378	regulation of single-species biofilm formation
CP162_05930	COG0805	protein transport
CP162_05945	COG0300	oxidoreductase activity
CP162_05995	COG0463	Glycosyl transferase, family 2
CP162_06020	COG0477	Major facilitator Superfamily
CP162_06040	COG0598	Magnesium transport protein CorA
CP162_06050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP162_06055	COG0513	Belongs to the DEAD box helicase family
CP162_06060	COG1253	flavin adenine dinucleotide binding
CP162_06100	COG0653	protein targeting
CP162_06115	COG3012	SEC-C Motif Domain Protein
CP162_06130	COG4264	IucA IucC family
CP162_06135	COG1120	ATPase activity
CP162_06140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_06145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_06150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP162_06155	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP162_06160	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP162_06170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CP162_06175	COG1160	GTP binding
CP162_06190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP162_06200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP162_06205	COG3104	oligopeptide transport
CP162_06225	COG4974	Belongs to the 'phage' integrase family
CP162_06260	COG0647	UMP catabolic process
CP162_06295	COG2835	tetraacyldisaccharide 4'-kinase activity
CP162_06300	COG0165	Argininosuccinate lyase
CP162_06320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP162_06335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP162_06350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP162_06365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP162_06390	COG3973	AAA domain
CP162_06410	COG0237	dephospho-CoA kinase activity
CP162_06425	COG0539	negative regulation of cytoplasmic translation
CP162_06430	COG2226	methyltransferase
CP162_06455	COG0765	amino acid transport
CP162_06480	COG0742	ribosomal rna small subunit methyltransferase
CP162_06485	COG0511	ligase activity, forming carbon-carbon bonds
CP162_06495	COG1461	Dihydroxyacetone kinase
CP162_06500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP162_06505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CP162_06590	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP162_06610	COG0473	3-isopropylmalate dehydrogenase activity
CP162_06650	COG0668	transmembrane transport
CP162_06685	COG0667	Aldo Keto reductase
CP162_06695	COG0205	6-phosphofructokinase activity
CP162_06705	COG1120	ATPase activity
CP162_06710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_06775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP162_06795	COG1119	ATPase activity
CP162_06820	COG0346	lactoylglutathione lyase activity
CP162_06865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP162_06870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP162_06875	COG0356	it plays a direct role in the translocation of protons across the membrane
CP162_06925	COG0460	homoserine dehydrogenase
CP162_06930	COG0019	diaminopimelate decarboxylase activity
CP162_06940	COG1620	l-lactate permease
CP162_06945	COG0247	lactate metabolic process
CP162_06950	COG1139	Iron-sulfur cluster binding protein
CP162_06955	COG1556	Lactate utilization protein
CP162_06985	COG1846	Transcriptional regulator
CP162_07010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP162_07015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP162_07045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP162_07065	COG2017	converts alpha-aldose to the beta-anomer
CP162_07085	COG2272	Belongs to the type-B carboxylesterase lipase family
CP162_07090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP162_07100	COG1132	(ABC) transporter
CP162_07105	COG0567	Dehydrogenase, E1 component
CP162_07105	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP162_07115	COG2239	Acts as a magnesium transporter
CP162_07145	COG4122	O-methyltransferase activity
CP162_07155	COG0297	glycogen (starch) synthase activity
CP162_07160	COG3527	Alpha-acetolactate decarboxylase
CP162_07185	COG0463	Glycosyl transferase, family 2
CP162_07190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP162_07195	COG1611	Belongs to the LOG family
CP162_07200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP162_07210	COG1113	amino acid transport
CP162_07220	COG1113	amino acid transport
CP162_07255	COG4166	transmembrane transport
CP162_07295	COG0601	transmembrane transport
CP162_07320	COG1122	ATPase activity
CP162_07325	COG4721	ABC-type cobalt transport system, permease component
CP162_07335	COG2354	Protein conserved in bacteria
CP162_07345	COG1132	(ABC) transporter
CP162_07350	COG1132	(ABC) transporter
CP162_07355	COG2824	Alkylphosphonate utilization operon protein PhnA
CP162_07370	COG0012	GTP binding
CP162_07385	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_07450	COG0288	reversible hydration of carbon dioxide
CP162_07465	COG2177	Part of the ABC transporter FtsEX involved in
CP162_07470	COG2884	Cell division ATP-binding protein ftsE
CP162_07480	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CP162_07495	COG0483	inositol monophosphate 1-phosphatase activity
CP162_07500	COG0483	inositol monophosphate 1-phosphatase activity
CP162_07540	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_07550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP162_07575	COG0174	glutamine synthetase
CP162_07600	COG0557	exoribonuclease II activity
CP162_07620	COG3323	Protein of unknown function (DUF1653)
CP162_07620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP162_07660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP162_07690	COG2860	membrane
CP162_07760	COG0423	glycine-tRNA ligase activity
CP162_07790	COG1381	Involved in DNA repair and RecF pathway recombination
CP162_07845	COG1022	Amp-dependent synthetase and ligase
CP162_07895	COG1132	(ABC) transporter
CP162_07900	COG1114	Component of the transport system for branched-chain amino acids
CP162_07905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP162_07915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP162_07930	COG0747	negative chemotaxis
CP162_07935	COG0601	transmembrane transport
CP162_07940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP162_07945	COG4172	Belongs to the ABC transporter superfamily
CP162_07955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CP162_07960	COG2391	methyltransferase activity
CP162_07970	COG4171	peptide transport system, permease
CP162_07985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP162_07990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP162_08010	COG1280	lysine exporter protein (LysE YggA)
CP162_08030	COG1596	polysaccharide export
CP162_08030	COG1555	photosystem II stabilization
CP162_08035	COG1307	EDD domain protein, DegV family
CP162_08040	COG0406	alpha-ribazole phosphatase activity
CP162_08050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP162_08065	COG2832	Protein of unknown function (DUF454)
CP162_08070	COG0569	domain protein
CP162_08070	COG2985	domain, Protein
CP162_08095	COG1530	ribonuclease E activity
CP162_08110	COG2423	ornithine cyclodeaminase activity
CP162_08120	COG0285	dihydrofolate synthase activity
CP162_08160	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP162_08195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP162_08205	COG0668	transmembrane transport
CP162_08285	COG1131	(ABC) transporter
CP162_08290	COG3336	cytochrome c oxidase
CP162_08295	COG1966	Carbon starvation protein
CP162_08315	COG0604	alcohol dehydrogenase
CP162_08320	COG4221	oxidoreductase activity
CP162_08340	COG1376	ErfK ybiS ycfS ynhG family protein
CP162_08360	COG2130	NADP-dependent
CP162_08365	COG1335	isochorismatase
CP162_08410	COG2197	response regulator
CP162_08460	COG1234	tRNA 3'-trailer cleavage
CP162_08485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CP162_08620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP162_08630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP162_08650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP162_08670	COG2217	Heavy metal translocating P-type atpase
CP162_08715	COG0033	Phosphoglucomutase
CP162_08730	COG0577	efflux transmembrane transporter activity
CP162_08730	COG1136	(ABC) transporter
CP162_08735	COG1136	(ABC) transporter
CP162_08735	COG0577	efflux transmembrane transporter activity
CP162_08770	COG2197	response regulator
CP162_08785	COG1045	serine acetyltransferase
CP162_08805	COG0371	Dehydrogenase
CP162_08825	COG1271	oxidase subunit
CP162_08830	COG1294	oxidase, subunit
CP162_08835	COG4988	ABC transporter
CP162_08840	COG4988	ABC transporter
CP162_08865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP162_08895	COG1597	lipid kinase activity
CP162_08910	COG0354	folic acid binding
CP162_08935	COG1780	Probably involved in ribonucleotide reductase function
CP162_08940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP162_08950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP162_08955	COG0047	phosphoribosylformylglycinamidine synthase activity
CP162_08960	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP162_08965	COG0386	Belongs to the glutathione peroxidase family
CP162_08985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP162_08990	COG0569	domain protein
CP162_08995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CP162_09000	COG0151	Belongs to the GarS family
CP162_09005	COG0537	adenosine 5'-monophosphoramidase activity
CP162_09015	COG2205	protein histidine kinase activity
CP162_09020	COG0745	RESPONSE REGULATOR receiver
CP162_09025	COG0477	Major facilitator Superfamily
CP162_09050	COG0028	Belongs to the TPP enzyme family
CP162_09095	COG1609	Transcriptional regulator
CP162_09105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP162_09125	COG1329	Transcriptional regulator
CP162_09130	COG2847	Copper chaperone PCu(A)C
CP162_09145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CP162_09155	COG0288	reversible hydration of carbon dioxide
CP162_09185	COG0477	Major facilitator Superfamily
CP162_09190	COG1957	nucleoside hydrolase
CP162_09210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP162_09225	COG1301	dicarboxylic acid transport
CP162_09230	COG1012	belongs to the aldehyde dehydrogenase family
CP162_09235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP162_09240	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CP162_09245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP162_09275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP162_09280	COG0302	gtp cyclohydrolase
CP162_09285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP162_09300	COG2027	D-alanyl-D-alanine carboxypeptidase
CP162_09305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP162_09310	COG0425	Belongs to the sulfur carrier protein TusA family
CP162_09310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP162_09315	COG1301	dicarboxylic acid transport
CP162_09340	COG2326	polyphosphate kinase activity
CP162_09360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP162_09410	COG1051	belongs to the nudix hydrolase family
CP162_09430	COG0242	peptide deformylase activity
CP162_09435	COG0456	acetyltransferase
CP162_09445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP162_09470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP162_09485	COG0280	phosphate acetyltransferase
CP162_09500	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_09510	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CP162_09515	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CP162_09545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP162_09550	COG1333	cytochrome c biogenesis protein
CP162_09560	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CP162_09565	COG3005	denitrification pathway
CP162_09590	COG4129	membrane
CP162_09625	COG0191	fructose-bisphosphate aldolase activity
CP162_09640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP162_09655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP162_09695	COG1131	(ABC) transporter
CP162_09725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP162_09740	COG1136	(ABC) transporter
CP162_09740	COG0577	efflux transmembrane transporter activity
CP162_09745	COG1136	(ABC) transporter
CP162_09750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP162_09775	COG1012	belongs to the aldehyde dehydrogenase family
CP162_09790	COG0789	Transcriptional regulator
CP162_09805	COG0443	Heat shock 70 kDa protein
CP162_09835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP162_09840	COG0601	transmembrane transport
CP162_09860	COG0247	lactate metabolic process
CP162_09860	COG2181	nitrate reductase activity
CP162_09875	COG1120	ATPase activity
CP162_09880	COG4139	cobalamin transport
CP162_09890	COG0829	nickel cation binding
CP162_09895	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP162_09900	COG0830	nickel cation binding
CP162_09905	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CP162_09910	COG0804	urea catabolic process
CP162_09915	COG0832	Belongs to the urease beta subunit family
CP162_09920	COG0831	urea catabolic process
CP162_09945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP162_09945	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP162_09965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP162_09980	COG1012	belongs to the aldehyde dehydrogenase family
CP162_09990	COG1472	Belongs to the glycosyl hydrolase 3 family
CP162_10000	COG4981	capsule polysaccharide biosynthetic process
CP162_10005	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP162_10005	COG2755	lipolytic protein G-D-S-L family
CP162_10020	COG0438	transferase activity, transferring glycosyl groups
CP162_10025	COG0500	methyltransferase
CP162_10070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP162_10075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP162_10075	COG3321	synthase
CP162_10080	COG0318	PFAM AMP-dependent synthetase and ligase
CP162_10095	COG5479	isomerase activity
CP162_10095	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP162_10110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP162_10115	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP162_10120	COG0671	phosphoesterase, PA-phosphatase related
CP162_10125	COG1216	Glycosyl transferase, family 2
CP162_10135	COG0671	phosphoesterase, PA-phosphatase related
CP162_10145	COG0584	glycerophosphoryl diester phosphodiesterase
CP162_10150	COG2271	Major facilitator Superfamily
CP162_10160	COG1120	ATPase activity
CP162_10165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP162_10170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP162_10180	COG0561	phosphatase activity
CP162_10195	COG2188	Transcriptional regulator
CP162_10215	COG0077	Prephenate dehydratase
CP162_10220	COG0154	amidase activity
CP162_10230	COG1316	TRANSCRIPTIONal
CP162_10245	COG1115	amino acid carrier protein
CP162_10265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CP162_10290	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_10300	COG0431	NADPH-dependent FMN reductase
CP162_10305	COG2814	Major facilitator Superfamily
CP162_10325	COG5650	phosphatidylinositol metabolic process
CP162_10345	COG2197	response regulator
CP162_10360	COG3764	Sortase (surface protein transpeptidase)
CP162_10365	COG0706	membrane insertase activity
CP162_10390	COG0564	pseudouridine synthase activity
CP162_10420	COG1131	(ABC) transporter
CP162_10440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP162_10455	COG0477	Major facilitator Superfamily
CP162_10460	COG0305	Participates in initiation and elongation during chromosome replication
CP162_10505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP162_10545	COG0783	Belongs to the Dps family
CP162_10550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP162_10555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CP162_10555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CP162_10565	COG1511	domain protein
CP162_10575	COG0577	efflux transmembrane transporter activity
CP162_10575	COG1136	(ABC) transporter
CP162_10590	COG4585	Histidine kinase
CP162_10595	COG2197	response regulator
CP162_10610	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP162_10625	COG2186	Transcriptional regulator
CP162_10630	COG0747	negative chemotaxis
CP162_10635	COG0601	transmembrane transport
CP162_10640	COG0444	Belongs to the ABC transporter superfamily
CP162_10645	COG4608	Belongs to the ABC transporter superfamily
CP162_10650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP162_10690	COG3422	double-strand break repair
CP162_10695	COG3547	Transposase (IS116 IS110 IS902 family)
CP162_10710	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CP162_10730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP162_10735	COG0512	Glutamine amidotransferase of anthranilate synthase
CP162_10745	COG0134	indole-3-glycerol-phosphate synthase activity
CP162_10745	COG0135	phosphoribosylanthranilate isomerase activity
CP162_10775	COG1687	branched-chain amino acid
CP162_10780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CP162_10785	COG1678	Uncharacterized ACR, COG1678
CP162_10790	COG0617	tRNA 3'-terminal CCA addition
CP162_10825	COG3409	Peptidoglycan-binding domain 1 protein
CP162_10825	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP162_10840	COG1192	Involved in chromosome partitioning
CP162_10855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP162_10865	COG0230	Belongs to the bacterial ribosomal protein bL34 family