locus-tag class description CULC0211_00020 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CULC0211_00050 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CULC0211_00090 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CULC0211_00140 ENOG4107SDZ Galactoside transport system permease protein mglC CULC0211_00150 ENOG4105C2J ABC transporter CULC0211_00260 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CULC0211_00340 ENOG4106KRW Has sphingomyelinase and hemolytic activity. Thought to act as a virulence factor CULC0211_00350 ENOG4105E0A ABC, transporter CULC0211_00360 ENOG4105TVJ transport system, permease CULC0211_00370 ENOG4105DQ5 transport system permease protein CULC0211_00380 ENOG4108MES Periplasmic binding protein CULC0211_00400 ENOG4108DT4 serine threonine protein kinase CULC0211_00420 ENOG4105CJN penicillin-binding protein CULC0211_00460 ENOG4105TV9 FHA Domain-Containing protein CULC0211_00460 ENOG4105TV9 FHA Domain-Containing protein CULC0211_00530 ENOG4105KHC sulfurtransferase CULC0211_00570 ENOG4105E0A ABC, transporter CULC0211_00580 ENOG4105EHG Permease protein CULC0211_00590 ENOG4105CJW magnesium transporter CULC0211_00600 ENOG4105CG3 alpha amylase, catalytic region CULC0211_00620 ENOG4105DA5 (ABC) transporter CULC0211_00640 ENOG4105WH1 Two component transcriptional regulator luxr family CULC0211_00710 ENOG4105K6V RNA polymerase CULC0211_00770 ENOG4108IJ8 ABC transporter CULC0211_00800 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) CULC0211_00820 ENOG41066NP positive regulation by symbiont of host immune response CULC0211_00840 ENOG4105FYV Amp nucleosidase CULC0211_00870 ENOG4107YXZ hydrolase, family 25 CULC0211_01000 ENOG4105DYN CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CULC0211_01020 ENOG4107QRT dEAD DEAH box helicase CULC0211_01080 ENOG4108Z0R Transferase CULC0211_01110 ENOG4108URH decarboxylase CULC0211_01130 ENOG4105K56 Transcriptional regulator CULC0211_01160 ENOG4108KK1 membrane protein AbrB duplication CULC0211_01180 ENOG4105EJ9 Membrane CULC0211_01200 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CULC0211_01210 ENOG4105CQ7 ATP-dependent helicase CULC0211_01220 ENOG4105EVB acetyltransferase CULC0211_01230 ENOG4105CF1 Alkylated DNA repair protein CULC0211_01240 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) CULC0211_01260 ENOG4105CCF Lysine exporter protein (Lyse ygga) CULC0211_01270 ENOG4105K8R UPF0145 protein CULC0211_01280 ENOG410848D S4 domain protein YaaA CULC0211_01320 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CULC0211_01330 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CULC0211_01350 ENOG4105C9K Endothelin-converting enzyme 1 CULC0211_01390 ENOG4105J1Z Arabinosyltransferase CULC0211_01400 ENOG4108K7T Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases CULC0211_01410 ENOG4108RG3 short-chain dehydrogenase reductase CULC0211_01420 ENOG4105IQ5 FAD linked oxidase domain protein CULC0211_01480 ENOG4108MKI Glycosyl transferase, family 2 CULC0211_01490 ENOG4107SIG periplasmic solute binding protein CULC0211_01500 ENOG4105DIK (ABC) transporter CULC0211_01510 ENOG4107RPQ ABC transporter CULC0211_01520 ENOG4107RBD ABC, transporter CULC0211_01530 ENOG4105DSE periplasmic solute binding protein CULC0211_01580 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CULC0211_01600 ENOG4105C8P )-transporter CULC0211_01630 ENOG4105CI1 PTS System CULC0211_01650 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CULC0211_02100 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CULC0211_02140 ENOG4105EVN Prephenate dehydrogenase CULC0211_02160 ENOG4108Z6B deaminase CULC0211_02170 ENOG4105EYF MMPL domain protein CULC0211_02180 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) CULC0211_02200 ENOG4105C6Z Gluconate CULC0211_02210 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CULC0211_02220 ENOG4105CPQ Dehydrogenase CULC0211_02230 ENOG4105CHR reductase CULC0211_02240 ENOG4105XT2 Transcriptional regulator CULC0211_02290 ENOG4105C6Z Gluconate CULC0211_02300 ENOG4105ZXK Dehydrogenase CULC0211_02320 ENOG4105JXH GntR family transcriptional regulator CULC0211_02330 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CULC0211_02360 ENOG4105F1K Glutamine amidotransferase CULC0211_02370 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) CULC0211_02400 ENOG4108DBC nitroreductase CULC0211_02420 ENOG4107RHR regulatoR CULC0211_02430 ENOG4105D3A purine nucleoside phosphorylase DeoD-type CULC0211_02440 ENOG4108J8C transporter major facilitator family protein CULC0211_02460 ENOG4107QSU Phosphoglucomutase phosphomannomutase alpha beta alpha domain CULC0211_02480 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein CULC0211_02500 ENOG4105PP6 Membrane CULC0211_02510 ENOG4105CIG ABC transporter CULC0211_02530 ENOG4105CFH Aspartokinase CULC0211_02560 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CULC0211_02580 ENOG4105CH6 catalase CULC0211_02700 ENOG4107QKW extracellular solute-binding protein family 1 CULC0211_02710 ENOG4105CXY transporter CULC0211_02720 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CULC0211_02730 ENOG4105BZU Histidine kinase CULC0211_02770 ENOG4108JPZ Monovalent cation H antiporter subunit D CULC0211_02790 ENOG4105D65 subunit l CULC0211_02810 ENOG4108NJC CULC0211_02840 ENOG4108IUX (ABC) transporter CULC0211_02870 ENOG4105BZ4 penicillin-binding protein CULC0211_02880 ENOG4105N0U Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) CULC0211_02920 ENOG4105IJJ transcriptional regulator, crp fnr family CULC0211_02960 ENOG4105P8F nudix hydrolase CULC0211_03100 ENOG4108I5C dEAD DEAH box helicase CULC0211_03120 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CULC0211_03130 ENOG4105EPD Oligopeptide transporter, Opt family CULC0211_03150 ENOG4105C6E dna polymerase iii CULC0211_03170 ENOG4105CEY Amp-dependent synthetase and ligase CULC0211_03210 ENOG4105C1B dTDP-glucose 4-6-dehydratase CULC0211_03260 ENOG4107QN2 dihydrolipoyl dehydrogenase CULC0211_03270 ENOG4105CFF transcriptional regulator CULC0211_03300 ENOG4105E33 succinate dehydrogenase CULC0211_03320 ENOG4106BRA Membrane CULC0211_03340 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CULC0211_03360 ENOG4105F1A Pyruvate formate-lyase CULC0211_03380 ENOG4105C6N Formate acetyltransferase CULC0211_03420 ENOG4105CEY Amp-dependent synthetase and ligase CULC0211_03450 ENOG4105BZU Histidine kinase CULC0211_03460 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CULC0211_03500 ENOG4105II7 pyrroline-5-carboxylate reductase CULC0211_03540 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) CULC0211_03560 ENOG4108RXW HAD-superfamily subfamily IB hydrolase CULC0211_03600 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) CULC0211_03630 ENOG4105C59 p-type ATPase CULC0211_03680 ENOG4108RH7 phosphoglycerate mutase CULC0211_03700 ENOG4107QIV Cytochrome c biogenesis protein CULC0211_03730 ENOG4105CRE cytochrome C CULC0211_03790 ENOG4107SIQ Naphthoate synthase CULC0211_03810 ENOG4105CEE C4-dicarboxylate transporter CULC0211_03820 ENOG4107TCW O-succinylbenzoate synthase CULC0211_03850 ENOG4105BZF Glycosyl transferase (Group 1 CULC0211_03870 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) CULC0211_03880 ENOG4105P52 geranylgeranyl reductase CULC0211_03900 ENOG410683Z Preprotein translocase SecE subunit CULC0211_03960 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CULC0211_04000 ENOG4105DSE periplasmic solute binding protein CULC0211_04020 ENOG4105DIK (ABC) transporter CULC0211_04030 ENOG4105CC5 ABC transporter CULC0211_04110 ENOG4105BZU Histidine kinase CULC0211_04120 ENOG4105WH1 Two component transcriptional regulator luxr family CULC0211_04160 ENOG4105CJ1 ABC, transporter CULC0211_04190 ENOG4108PJD permease CULC0211_04200 ENOG4105F1A Pyruvate formate-lyase CULC0211_04340 ENOG4105VBF alkaline shock protein CULC0211_04350 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) CULC0211_04460 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein CULC0211_04530 ENOG4105C44 Serine transporter CULC0211_04540 ENOG4105EJQ L-serine dehydratase CULC0211_04550 ENOG4105HDK L-asparaginase CULC0211_04570 ENOG4105YVM Phosphoesterase, PA-phosphatase related CULC0211_04670 ENOG4105EG2 ABC transporter, permease CULC0211_04710 ENOG4108IJ9 (ABC) transporter CULC0211_04720 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CULC0211_04730 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) CULC0211_04820 ENOG4108ZT0 50S ribosomal protein l17 CULC0211_04860 ENOG41090GG peptidase S8 and S53, subtilisin, kexin, sedolisin CULC0211_04890 ENOG4105EC2 ftsk spoIIIe CULC0211_05620 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CULC0211_05670 ENOG41080E2 ribosomal-protein-alanine acetyltransferase CULC0211_05750 ENOG4107QVP Dehydrogenase CULC0211_05840 ENOG4108UMI ABC transporter, permease CULC0211_05860 ENOG4105D01 (LipO)protein CULC0211_05870 ENOG4105D01 (LipO)protein CULC0211_05900 ENOG4105DSE periplasmic solute binding protein CULC0211_05910 ENOG4105DIK (ABC) transporter CULC0211_05920 ENOG4107RBD ABC, transporter CULC0211_05930 ENOG4107RPQ ABC transporter CULC0211_05950 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CULC0211_06040 ENOG4105DQ5 transport system permease protein CULC0211_06050 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) CULC0211_06070 ENOG4108IQK o-acetylhomoserine CULC0211_06080 ENOG4105E9K Isocitrate dehydrogenase CULC0211_06090 ENOG4105F27 Major Facilitator CULC0211_06100 ENOG4108Z5V transcriptional regulator, merr family CULC0211_06140 ENOG4105C31 Tryptophanyl-tRNA synthetase CULC0211_06150 ENOG4107H3J ribonuclease CULC0211_06160 ENOG4105DZ1 carboxypeptidase CULC0211_06230 ENOG4107QSU Phosphoglucomutase phosphomannomutase alpha beta alpha domain CULC0211_06240 ENOG4107RM1 amidohydrolase CULC0211_06260 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) CULC0211_06290 ENOG4108JIK carboxylase CULC0211_06300 ENOG4105KHC sulfurtransferase CULC0211_06310 ENOG4105D7Z glutathione synthase CULC0211_06320 ENOG4105EXC Acyl-transferase CULC0211_06340 ENOG4107WR6 Maf-like protein CULC0211_06350 ENOG4108RVA ribokinase CULC0211_06360 ENOG4105ETE Transcriptional regulator (LacI family CULC0211_06380 ENOG4105D8K carboxyl transferase CULC0211_06390 ENOG4105D8K carboxyl transferase CULC0211_06400 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CULC0211_06440 ENOG4108IUW ABC transporter CULC0211_06490 ENOG4105EHG Permease protein CULC0211_06500 ENOG4105E0A ABC, transporter CULC0211_06560 ENOG4107TB5 TRANSCRIPTIONal CULC0211_06590 ENOG4105K51 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity) CULC0211_06640 ENOG4105EIP mannose-6-phosphate isomerase CULC0211_06700 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CULC0211_06710 ENOG4105BZU Histidine kinase CULC0211_06730 ENOG4105MJ2 Competence protein CULC0211_06740 ENOG4108S7Q sigma 54 modulation protein ribosomal protein S30ea CULC0211_06810 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) CULC0211_06830 ENOG4108RAV Conserved protein CULC0211_06840 ENOG4108Z66 YbaK ebsC protein CULC0211_06910 ENOG4105C1J atp-dependent rna helicase CULC0211_06960 ENOG4105C4R Atp-dependent dna helicase CULC0211_06980 ENOG4105E09 nadh pyrophosphatase CULC0211_07030 ENOG41063PX domain protein CULC0211_07140 ENOG4105C85 amino acid CULC0211_07150 ENOG4107QSA Oxaloacetate decarboxylase CULC0211_07160 ENOG4107QX3 carboxylase CULC0211_07180 ENOG4107QSA Oxaloacetate decarboxylase CULC0211_07200 ENOG4107TK4 histidinol-phosphate phosphatase CULC0211_07210 ENOG4107TK4 histidinol-phosphate phosphatase CULC0211_07240 ENOG4105CFC Transporter CULC0211_07250 ENOG4105CAK Cell division ATP-binding protein ftsE CULC0211_07260 ENOG4107RYD Part of the ABC transporter FtsEX involved in cellular division (By similarity) CULC0211_07280 ENOG4107B2H carbonic anhydrase CULC0211_07320 ENOG4105CM4 permease protein CULC0211_07330 ENOG4108IPW abc transporter atp-binding protein CULC0211_07390 ENOG4105MS9 Resuscitation-promoting factor CULC0211_07400 ENOG4105VEQ Cold shock protein CULC0211_07440 ENOG4105C7N Xanthine uracil vitamin C permease CULC0211_07490 ENOG4105BZN citrate synthase CULC0211_07500 ENOG41081K0 peptidylprolyl cis-trans isomerase CULC0211_07540 ENOG4105CV8 reductase CULC0211_07550 ENOG4108VUG Enoyl-CoA hydratase CULC0211_07570 ENOG4107QN1 sodium solute CULC0211_07590 ENOG4108WKN secreted protein CULC0211_07620 ENOG4107QI1 Mate efflux family protein CULC0211_07670 ENOG4108J59 Extracellular solute-binding protein, family 5 CULC0211_07680 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CULC0211_07690 ENOG4108EU3 peptide transport system, permease CULC0211_07780 ENOG4108RM3 Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo CULC0211_07790 ENOG4107QRT dEAD DEAH box helicase CULC0211_07810 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) CULC0211_07850 ENOG4106D2I Chorismate mutase CULC0211_07870 ENOG41061JJ Peptidase family M23 CULC0211_07910 ENOG4105CDA abc transporter atp-binding protein CULC0211_07920 ENOG4107UBR Extracellular solute-binding protein family 3 CULC0211_07930 ENOG4108Q1T ABC transporter CULC0211_07940 ENOG4105DRP amino acid AbC transporter CULC0211_07960 ENOG4105EC0 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity) CULC0211_08020 ENOG4105NRA 50s ribosomal protein l31 type b CULC0211_08040 ENOG4105ETX regulatoR CULC0211_08050 ENOG41062D9 Histidine kinase CULC0211_08060 ENOG4105C0H protease CULC0211_08070 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CULC0211_08090 ENOG41080FJ Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) CULC0211_08120 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CULC0211_08160 ENOG4108VGI doxx family CULC0211_08180 ENOG4105FF9 glycosyl transferase, family 39 CULC0211_08190 ENOG4105C94 Transporter CULC0211_08200 ENOG4108K88 Membrane CULC0211_08230 ENOG4105F8V Hydrolase, tatD family CULC0211_08240 ENOG4106839 domain protein CULC0211_08270 ENOG4105C5H ABC transporter CULC0211_08320 ENOG4105CSR polyphosphate kinase 2 CULC0211_08340 ENOG4108AZI Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity) CULC0211_08400 ENOG4108HGY Proline imino-peptidase CULC0211_08410 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) CULC0211_08430 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) CULC0211_08440 ENOG4105EA8 2-Nitropropane dioxygenase CULC0211_08480 ENOG4108IUM Glycogen debranching enzyme CULC0211_08490 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CULC0211_08500 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) CULC0211_08510 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CULC0211_08530 ENOG41082JN Transcriptional regulator CULC0211_08550 ENOG4105D5Q Arginine ornithine antiporter CULC0211_08560 ENOG4105DXN mazG family CULC0211_08680 ENOG4105T1M mycothiol conjugate amidase mca CULC0211_08900 ENOG4105C3G gtp-binding protein CULC0211_08920 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CULC0211_08930 ENOG4105BZ1 (ABC) transporter CULC0211_08940 ENOG4105BZ1 (ABC) transporter CULC0211_08950 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CULC0211_08960 ENOG4105CKW Inner membrane protein yedI CULC0211_08980 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein CULC0211_08990 ENOG4108JJB ABC transporter CULC0211_09010 ENOG4105CAT Cytidine monophosphate kinase CULC0211_09020 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) CULC0211_09030 ENOG4108J59 Extracellular solute-binding protein, family 5 CULC0211_09040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CULC0211_09050 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CULC0211_09080 ENOG4105C19 ABC transporter CULC0211_09100 ENOG4108TVX serine protease CULC0211_09140 ENOG4105CI3 gtp-binding protein typa CULC0211_09180 ENOG4108Z4U Ferredoxin CULC0211_09220 ENOG4105C85 amino acid CULC0211_09240 ENOG4105C85 amino acid CULC0211_09270 ENOG4108URH decarboxylase CULC0211_09280 ENOG4105EEI dihydropteroate synthase CULC0211_09290 ENOG4105C3Q Glycosyl transferase, family 2 CULC0211_09340 ENOG4107FQX Alpha-acetolactate decarboxylase CULC0211_09350 ENOG4107QPH glycogen) synthase CULC0211_09370 ENOG4107ZBN O-methyltransferase CULC0211_09380 ENOG4105DU6 RNA polymerase CULC0211_09430 ENOG4105CJW magnesium transporter CULC0211_09450 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CULC0211_09460 ENOG4105BZ1 (ABC) transporter CULC0211_09480 ENOG4105F9E Shikimate 5-dehydrogenase CULC0211_09490 ENOG4105EBR Carboxylesterase CULC0211_09540 ENOG4107WI4 Aldose-1-epimerase CULC0211_09580 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) CULC0211_09630 ENOG4105CK7 Sodium proline symporter CULC0211_09640 ENOG4105C0D helicase CULC0211_09690 ENOG4105FS7 Transcriptional regulator CULC0211_09720 ENOG4105E98 transcriptional regulator DeoR family CULC0211_09760 ENOG41080R8 Conserved Protein CULC0211_09770 ENOG4107QR9 Iron-sulfur cluster binding protein CULC0211_09780 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CULC0211_09790 ENOG4105DAA L-lactate CULC0211_09810 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CULC0211_09820 ENOG4105D6E homoserine dehydrogenase CULC0211_09920 ENOG4107UH5 it plays a direct role in the translocation of protons across the membrane (By similarity) CULC0211_09930 ENOG4105ZA1 atp synthase CULC0211_09940 ENOG4107Z0K Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) CULC0211_10070 ENOG4105DKW ABC transporter CULC0211_10110 ENOG4105C10 Electron transfer flavoprotein CULC0211_10240 ENOG4105EHG Permease protein CULC0211_10250 ENOG4105E0A ABC, transporter CULC0211_10290 ENOG4105CTQ phosphohexokinase CULC0211_10320 ENOG4105CPC Aldo Keto reductase CULC0211_10340 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) CULC0211_10350 ENOG4105CHF Glutathione S-transferase CULC0211_10410 ENOG4105C7K acetolactate synthase CULC0211_10490 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CULC0211_10530 ENOG4105ERH Fumarylacetoacetate hydrolase CULC0211_10630 ENOG4108HFV CULC0211_10650 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CULC0211_10660 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CULC0211_10670 ENOG4105C3U ABC transporter CULC0211_10690 ENOG4105DEF Extracellular solute-binding protein, family 5 CULC0211_10790 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CULC0211_10800 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) CULC0211_10810 ENOG4105DP4 dak2 domain fusion protein ylov CULC0211_10830 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit CULC0211_10840 ENOG4106H78 methyltransferase CULC0211_10880 ENOG4108JEH abc transporter atp-binding protein CULC0211_10890 ENOG4105E5Q amino acid AbC transporter CULC0211_10950 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CULC0211_11010 ENOG4105EEM helicase CULC0211_11030 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) CULC0211_11060 ENOG41084BS 50S ribosomal protein L35 CULC0211_11150 ENOG4105C8Y Acetylornithine aminotransferase CULC0211_11160 ENOG4105DBV ornithine carbamoyltransferase CULC0211_11190 ENOG4105CH7 arginosuccinase CULC0211_11200 ENOG4105W49 UPF0434 protein CULC0211_11230 ENOG4105DSU hydrolase CULC0211_11310 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CULC0211_11330 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) CULC0211_11350 ENOG4105DUX Transporter CULC0211_11360 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CULC0211_11380 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) CULC0211_11410 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) CULC0211_11420 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CULC0211_11440 ENOG4108SEA Esterase CULC0211_11450 ENOG4105FF5 Membrane CULC0211_11460 ENOG4108HUF Transporter CULC0211_11470 ENOG4105S6R Iron-hydroxamate transporter permease subunit CULC0211_11480 ENOG4108U1V ABC transporter, permease CULC0211_11490 ENOG4105E0A ABC, transporter CULC0211_11500 ENOG4105DUU IucA IucC family protein CULC0211_11530 ENOG4105K5B UPF0225 protein CULC0211_11640 ENOG4105C37 (CBS) domain CULC0211_11650 ENOG4105C1J atp-dependent rna helicase CULC0211_11660 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CULC0211_11680 ENOG4105D7N magnesium and cobalt transport protein CorA CULC0211_11700 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) CULC0211_11750 ENOG4105CSH Transporter CULC0211_11760 ENOG4105CQB FAD linked oxidase domain protein CULC0211_11770 ENOG4105C09 Bile acid CULC0211_11820 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) CULC0211_11850 ENOG4105CTK cobaltochelatase, cobn subunit CULC0211_11890 ENOG4105C85 amino acid CULC0211_11930 ENOG4108RG3 short-chain dehydrogenase reductase CULC0211_11960 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CULC0211_11980 ENOG4107TMB Transcriptional regulator CULC0211_12010 ENOG4107QD7 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity) CULC0211_12020 ENOG4105E5F proteasome CULC0211_12050 ENOG4105DFM M18 family aminopeptidase CULC0211_12090 ENOG4108IJ0 Aspartate ammonia-lyase CULC0211_12100 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CULC0211_12130 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 CULC0211_12140 ENOG4105C3R Methionine synthase CULC0211_12180 ENOG4107SET aldo keto reductase CULC0211_12200 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) CULC0211_12230 ENOG4108V1U phospholipid-binding protein CULC0211_12250 ENOG4108UTZ Dihydroxyacetone kinase CULC0211_12260 ENOG4105CMT Dihydroxyacetone kinase CULC0211_12270 ENOG4105C5H ABC transporter CULC0211_12400 ENOG4105ZXU NLP P60 protein CULC0211_12460 ENOG4105CAG UPF0210 protein CULC0211_12690 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) CULC0211_12820 ENOG4105C2M dna polymerase I CULC0211_12960 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CULC0211_12970 ENOG4105C5H ABC transporter CULC0211_12980 ENOG4105VG1 fes assembly suf system protein CULC0211_12990 ENOG4108UNV SUF system FeS assembly protein, NifU family CULC0211_13010 ENOG4105C3K feS assembly ATPase SufC CULC0211_13050 ENOG4107JC6 Membrane CULC0211_13100 ENOG4105CV1 Transketolase (EC 2.2.1.1) CULC0211_13110 ENOG4107QQX Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CULC0211_13190 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CULC0211_13210 ENOG4105CHW UPF0052 protein CULC0211_13230 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) CULC0211_13320 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) CULC0211_13400 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CULC0211_13420 ENOG4105CD3 dihydroorotase CULC0211_13440 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) CULC0211_13450 ENOG4105ECP epimerase CULC0211_13500 ENOG4105DC7 peptidase M24 CULC0211_13540 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase CULC0211_13560 ENOG4105E2X shikimate dehydrogenase CULC0211_13580 ENOG41080G3 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) CULC0211_13680 ENOG4108UZX fmn reductase CULC0211_13690 ENOG4105EJQ L-serine dehydratase CULC0211_13710 ENOG4105C5X domain protein CULC0211_13720 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CULC0211_13750 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CULC0211_13770 ENOG4108NY6 Extracellular solute-binding protein, family 5 CULC0211_13780 ENOG4107RTU Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CULC0211_13830 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) CULC0211_13850 ENOG4105C29 acyl-CoA thioesterase CULC0211_13880 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CULC0211_13900 ENOG4105E2K Glycosyl transferase (Group 1 CULC0211_13910 ENOG4107YQ3 lipid a biosynthesis lauroyl acyltransferase CULC0211_13950 ENOG4105DBE peroxidase CULC0211_14010 ENOG4105E0X reductase CULC0211_14020 ENOG4107JTW chlorite dismutase CULC0211_14260 ENOG4105JNJ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) CULC0211_14270 ENOG4105D3R alkyl hydroperoxide reductase CULC0211_14280 ENOG4105C5Q Transcriptional regulator CULC0211_14300 ENOG4105CQ7 ATP-dependent helicase CULC0211_14340 ENOG4105E98 transcriptional regulator DeoR family CULC0211_14350 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CULC0211_14360 ENOG4105E98 transcriptional regulator DeoR family CULC0211_14370 ENOG4105DE4 1-phosphofructokinase CULC0211_14380 ENOG4105DM4 PTS System CULC0211_14390 ENOG4105KRI phosphocarrier protein (HPr CULC0211_14400 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone CULC0211_14430 ENOG4105C2W permease CULC0211_14440 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CULC0211_14470 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) CULC0211_14500 ENOG4105C99 atpase involved in dna repair CULC0211_14560 ENOG4107ZYJ bioY protein CULC0211_14570 ENOG4108JJB ABC transporter CULC0211_14580 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) CULC0211_14600 ENOG4105WBV Transcriptional regulator CULC0211_14670 ENOG4105CN5 Metallo-Beta-Lactamase CULC0211_14750 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) CULC0211_14780 ENOG4107QMU Mate efflux family protein CULC0211_14870 ENOG4107XFJ UPF0246 protein CULC0211_14880 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) CULC0211_14890 ENOG4105CNG UPF0061 protein CULC0211_14900 ENOG4105CKI cobalamin synthesis protein CULC0211_14910 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CULC0211_14930 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CULC0211_15020 ENOG4105CJN penicillin-binding protein CULC0211_15040 ENOG4105DZP Membrane-associated zinc metalloprotease CULC0211_15070 ENOG41068X0 Protein of unknown function (DUF2631) CULC0211_15170 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CULC0211_15190 ENOG4105C0P Mg chelatase subunit ChlI CULC0211_15200 ENOG41082RQ UPF0102 protein CULC0211_15220 ENOG4107Y5I Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) CULC0211_15230 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) CULC0211_15250 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) CULC0211_15260 ENOG4105D06 uba thif-type nad fad binding protein CULC0211_15270 ENOG4105DWF phosphomethylpyrimidine kinase CULC0211_15300 ENOG4107QYR Signal peptidase i CULC0211_15330 ENOG4105DM4 PTS System CULC0211_15350 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) CULC0211_15360 ENOG4107XUM An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) CULC0211_15400 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) CULC0211_15450 ENOG4108375 Acylphosphatase (EC 3.6.1.7) CULC0211_15520 ENOG4105DCF alanine dehydrogenase CULC0211_15530 ENOG4107R37 Glutamate dehydrogenase CULC0211_15540 ENOG4105BZW Glycerate kinase CULC0211_15570 ENOG4105CH2 amidohydrolase CULC0211_15600 ENOG4105CA9 Pyruvate kinase CULC0211_15620 ENOG4105DK0 Indole-3-glycerol phosphate synthase CULC0211_15660 ENOG4108MWI inositol mono-phosphatase CULC0211_15790 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) CULC0211_15850 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CULC0211_15860 ENOG4105C7B Threonine dehydratase CULC0211_15940 ENOG4105HDK L-asparaginase CULC0211_15980 ENOG4107VQS DivIVA family CULC0211_16000 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) CULC0211_16010 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CULC0211_16020 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CULC0211_16040 ENOG4105DFU Cell wall formation (By similarity) CULC0211_16100 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CULC0211_16110 ENOG4105CJN penicillin-binding protein CULC0211_16200 ENOG41072RD Membrane CULC0211_16210 ENOG4105KYH transcriptional regulatory protein CULC0211_16230 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase CULC0211_16270 ENOG4105DKQ ROK family CULC0211_16280 ENOG4105JNK Glycosyl transferase (Group 1 CULC0211_16300 ENOG4105K4H Nlp p60 protein CULC0211_16400 ENOG4108YZT Adenosylcobinamide kinase CULC0211_16410 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) CULC0211_16430 ENOG4105CM2 brancheD-chain amino acid aminotransferase CULC0211_16470 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor CULC0211_16480 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) CULC0211_16530 ENOG4105E0A ABC, transporter CULC0211_16540 ENOG4105TVJ transport system, permease CULC0211_16550 ENOG4105DQ5 transport system permease protein CULC0211_16600 ENOG4105C5F glutamine synthetase CULC0211_16630 ENOG410836F Transposase CULC0211_16670 ENOG4108J08 Csbd family CULC0211_16680 ENOG4105D3Y Na H antiporter CULC0211_16710 ENOG4105D98 threonine synthase CULC0211_16770 ENOG4105C5F glutamine synthetase CULC0211_16820 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CULC0211_16830 ENOG4105CVJ phosphoglycerate mutase CULC0211_16850 ENOG4105EGD dinuclear metal center protein, YbgI family CULC0211_16910 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) CULC0211_16930 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CULC0211_16940 ENOG4108YIQ Alpha beta hydrolase CULC0211_16990 ENOG4105EN6 Membrane CULC0211_17110 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) CULC0211_17160 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) CULC0211_17270 ENOG4108IQE Amp-dependent synthetase and ligase CULC0211_17290 ENOG4105DGW oligopeptidase A CULC0211_17300 ENOG4105EBR Carboxylesterase CULC0211_17350 ENOG4105BZ1 (ABC) transporter CULC0211_17360 ENOG4105CWM branched-chain amino acid transport system II carrier protein CULC0211_17370 ENOG4105DEN Luciferase family CULC0211_17390 ENOG4105C94 Transporter CULC0211_17420 ENOG4105DEF Extracellular solute-binding protein, family 5 CULC0211_17440 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CULC0211_17450 ENOG4108JQ5 ABC transporter CULC0211_17470 ENOG4105DFA alanine racemase domain protein CULC0211_17480 ENOG4105CUC YeeE YedE family protein CULC0211_17490 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CULC0211_17530 ENOG4108JQ5 ABC transporter CULC0211_17540 ENOG4105E2Y ABC, transporter CULC0211_17590 ENOG4105CCF Lysine exporter protein (Lyse ygga) CULC0211_17640 ENOG4107Z8D degv family CULC0211_17650 ENOG4105CVJ phosphoglycerate mutase CULC0211_17670 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) CULC0211_17700 ENOG4105D0C transport protein CULC0211_17760 ENOG4105C03 ribonuclease CULC0211_17790 ENOG4105CIF Ornithine Cyclodeaminase CULC0211_17810 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CULC0211_17890 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation CULC0211_17920 ENOG4105EUB pirin domain protein CULC0211_17940 ENOG4105MC2 DSBA oxidoreductase CULC0211_17960 ENOG4105D8X mechanosensitive ion channel CULC0211_18120 ENOG4108M15 ABC transporter CULC0211_18130 ENOG4105E4J Cytochrome c oxidase caa3-type, assembly factor ctag-related protein CULC0211_18140 ENOG4105D22 carbon starvation protein CULC0211_18170 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin CULC0211_18180 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CULC0211_18190 ENOG4105EMU Dehydrogenase CULC0211_18220 ENOG4107UBC ErfK ybiS ycfS ynhG family protein CULC0211_18230 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein CULC0211_18240 ENOG4108RWI nicotinamidase CULC0211_18330 ENOG4105WH1 Two component transcriptional regulator luxr family CULC0211_18350 ENOG4108ZJ4 polysaccharide deacetylase CULC0211_18420 ENOG4108RQ5 Beta-lactamase domain-containing protein CULC0211_18470 ENOG4107RKP Nicotinate phosphoribosyltransferase CULC0211_18540 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CULC0211_18560 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CULC0211_18570 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) CULC0211_18580 ENOG4105WAZ (Glutaredoxin-like protein) NrdH CULC0211_18600 ENOG4107RA1 nh(3)-dependent nad( ) synthetase CULC0211_18680 ENOG41082SX arsR family transcriptional regulator CULC0211_18690 ENOG4105C59 p-type ATPase CULC0211_18720 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CULC0211_18750 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CULC0211_18760 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CULC0211_18810 ENOG4105D7W serine acetyltransferase CULC0211_18840 ENOG4105C4M (Ubiquinol oxidase) subunit I CULC0211_18850 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CULC0211_18860 ENOG4108JJ9 ABC, transporter CULC0211_18870 ENOG4108JJ9 ABC, transporter CULC0211_18920 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) CULC0211_18980 ENOG4105CBD Diacylglycerol kinase CULC0211_19010 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) CULC0211_19060 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) CULC0211_19070 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CULC0211_19090 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii CULC0211_19100 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I CULC0211_19110 ENOG410839H phosphoribosylformylglycinamidine synthase CULC0211_19120 ENOG4108V06 Glutathione peroxidase CULC0211_19160 ENOG4105C83 adenylosuccinate lyase CULC0211_19170 ENOG4107ZYR domain protein CULC0211_19180 ENOG4105CZN Potassium uptake protein CULC0211_19190 ENOG4105C12 Phosphoribosylglycinamide synthetase CULC0211_19200 ENOG4107ZUX Histidine triad (HIT) protein CULC0211_19220 ENOG4105BZU Histidine kinase CULC0211_19230 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CULC0211_19240 ENOG4105C57 major facilitator superfamily CULC0211_19290 ENOG4105C7K acetolactate synthase CULC0211_19400 ENOG4105C2N RNA methyltransferase TrmH family group 3 CULC0211_19440 ENOG4108VJ1 Transcriptional regulator (CarD family CULC0211_19470 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CULC0211_19490 ENOG4108V9Q carbonic anhydrase CULC0211_19530 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CULC0211_19560 ENOG4105DU0 nucleoside hydrolase CULC0211_19630 ENOG4105CRK lysyL-tRNA synthetase CULC0211_19670 ENOG4105C26 Dehydrogenase CULC0211_19680 ENOG4105C94 Transporter CULC0211_19700 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) CULC0211_19770 ENOG4105EUJ GTP cyclohydrolase i CULC0211_19780 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CULC0211_19790 ENOG4108UGV hypoxanthine phosphoribosyltransferase CULC0211_19820 ENOG4105F0N pyrophosphate phospho-hydrolase CULC0211_19830 ENOG4105WZW rhodanese family CULC0211_19840 ENOG4107QJT sodium dicarboxylate symporter CULC0211_19890 ENOG4105CSR polyphosphate kinase 2 CULC0211_19950 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) CULC0211_19980 ENOG4105D65 subunit l CULC0211_19990 ENOG4105MKQ Monovalent cation H antiporter subunit C CULC0211_20000 ENOG4108JPZ Monovalent cation H antiporter subunit D CULC0211_20040 ENOG4108U8T Mannosyltransferase CULC0211_20080 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) CULC0211_20100 ENOG4105CGK Exodeoxyribonuclease III CULC0211_20110 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) CULC0211_20130 ENOG4105CJ1 ABC, transporter CULC0211_20160 ENOG4105CT1 (ABC) transporter CULC0211_20190 ENOG4108IJ2 phosphate acetyltransferase CULC0211_20230 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR CULC0211_20240 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) CULC0211_20330 ENOG4105CRE cytochrome C CULC0211_20360 ENOG4105EAU Plays a role in nitrite reduction (By similarity) CULC0211_20370 ENOG4108W6G cytochrome C CULC0211_20470 ENOG4107RCW fructose-bisphosphate aldolase CULC0211_20500 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) CULC0211_20530 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CULC0211_20620 ENOG4105CJ1 ABC, transporter CULC0211_20700 ENOG4105C19 ABC transporter CULC0211_20710 ENOG4105DJY efflux transporter, rnd family, mfp subunit CULC0211_20720 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CULC0211_20760 ENOG4105C26 Dehydrogenase CULC0211_20790 ENOG4105KNI merR family transcriptional Regulator CULC0211_20820 ENOG4105CFG Acts as a chaperone (By similarity) CULC0211_20880 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CULC0211_20930 ENOG4105DF6 Fe-S oxidoreductase CULC0211_20960 ENOG4105E0A ABC, transporter CULC0211_20970 ENOG4108ESU Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity) CULC0211_20990 ENOG4105ICD Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) CULC0211_21000 ENOG4107S16 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) CULC0211_21010 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) CULC0211_21020 ENOG4105HFU Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) CULC0211_21030 ENOG4105CQM Urea amidohydrolase subunit alpha CULC0211_21040 ENOG4105KI2 Urea amidohydrolase subunit beta CULC0211_21050 ENOG4108YZ9 Urea amidohydrolase subunit gamma CULC0211_21090 ENOG4105CRK lysyL-tRNA synthetase CULC0211_21130 ENOG4105C6Y Udp-glucose 6-dehydrogenase CULC0211_21150 ENOG4105C26 Dehydrogenase CULC0211_21190 ENOG4108JJB ABC transporter CULC0211_21230 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) CULC0211_21250 ENOG41073B4 coagulation factor 5 8 type domain-containing protein CULC0211_21260 ENOG4105EXC Acyl-transferase CULC0211_21290 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) CULC0211_21300 ENOG4108M6P methyltransferase CULC0211_21390 ENOG4105D8K carboxyl transferase CULC0211_21400 ENOG4107EEY synthase CULC0211_21440 ENOG4107YB1 Trehalose corynomycolyl transferase CULC0211_21450 ENOG4108VJY integral membrane protein CULC0211_21470 ENOG4107ISF Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids CULC0211_21480 ENOG4106YN8 Prenyltransferase CULC0211_21500 ENOG410602S Transferase CULC0211_21520 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CULC0211_21530 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CULC0211_21540 ENOG4105CXY transporter CULC0211_21560 ENOG4105E0A ABC, transporter CULC0211_21570 ENOG4105EHG Permease protein CULC0211_21580 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CULC0211_21600 ENOG4108KP7 hydrolase CULC0211_21640 ENOG4105FDP GntR family transcriptional regulator CULC0211_21680 ENOG4105CQC Prephenate dehydratase CULC0211_21710 ENOG4108KGH TRANSCRIPTIONal CULC0211_21740 ENOG4105BZG amino acid carrier protein CULC0211_21750 ENOG4105BZG amino acid carrier protein CULC0211_21780 ENOG4105D9N nucleoside CULC0211_21840 ENOG4108YYH Nadph-dependent fmn reductase CULC0211_21850 ENOG4107RSM transcriptional regulator CULC0211_21860 ENOG4105D94 Major Facilitator Superfamily CULC0211_21900 ENOG4108VJY integral membrane protein CULC0211_21940 ENOG4105WH1 Two component transcriptional regulator luxr family CULC0211_21980 ENOG4108RN7 integral membrane protein CULC0211_21990 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CULC0211_22040 ENOG4105DR9 pseudouridine synthase CULC0211_22060 ENOG4105DVE abc transporter atp-binding protein CULC0211_22100 ENOG41080RH Thioredoxin CULC0211_22140 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) CULC0211_22180 ENOG41079KZ Major Facilitator Superfamily CULC0211_22200 ENOG4105BZP glycoside hydrolase 15-related CULC0211_22220 ENOG4107YH6 single-stranded DNA-binding protein CULC0211_22260 ENOG4105BZ4 penicillin-binding protein CULC0211_22300 ENOG4108RKS Short-chain dehydrogenase reductase Sdr CULC0211_22330 ENOG4107XFB conserved TRANSMEMBRANE PROTEIN CULC0211_22350 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction CULC0211_22360 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) CULC0211_22390 ENOG4105ECB domain protein CULC0211_22450 ENOG4105BZU Histidine kinase CULC0211_22460 ENOG4105WH1 Two component transcriptional regulator luxr family CULC0211_22510 ENOG4105CPN adenine deaminase CULC0211_22530 ENOG4105DKQ ROK family CULC0211_22540 ENOG4107EJG GntR family transcriptional regulator CULC0211_22550 ENOG4105DEF Extracellular solute-binding protein, family 5 CULC0211_22560 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CULC0211_22580 ENOG4108JQ7 (ABC) transporter CULC0211_22590 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) CULC0211_22650 ENOG4105C26 Dehydrogenase CULC0211_22660 ENOG4105D5Q Arginine ornithine antiporter CULC0211_22730 ENOG4106178 UPF0339 protein CULC0211_22760 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) CULC0211_22780 ENOG4105EWK phytoene CULC0211_22800 ENOG4105CRQ synthase (Component I) CULC0211_22810 ENOG4105RGK anthranilate synthase component ii CULC0211_22830 ENOG4105DK0 Indole-3-glycerol phosphate synthase CULC0211_22840 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) CULC0211_22870 ENOG4105DHU Bile acid CULC0211_22900 ENOG4108UMN azlc family CULC0211_22910 ENOG4108UJU UPF0301 protein CULC0211_22920 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate CULC0211_22960 ENOG4105EMN RNA polymerase sigma factor CULC0211_22970 ENOG4105C3M thioredoxin reductase CULC0211_22990 ENOG4108E1C hydrolase CULC0211_23020 ENOG4107QJE Chromosome Partitioning Protein CULC0211_23070 ENOG41084CH 50S ribosomal protein l34