locus-tag	class	description
LC1Nh_0004	COG1125	glycine betaine transport
LC1Nh_0004	COG0517	IMP dehydrogenase activity
LC1Nh_0014	COG0346	lactoylglutathione lyase activity
LC1Nh_0026	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LC1Nh_0028	COG1136	(ABC) transporter
LC1Nh_0030	COG0577	efflux transmembrane transporter activity
LC1Nh_0031	COG0577	efflux transmembrane transporter activity
LC1Nh_0032	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LC1Nh_0034	COG1164	Oligoendopeptidase f
LC1Nh_0035	COG1363	Peptidase, m42
LC1Nh_0042	COG0443	Heat shock 70 kDa protein
LC1Nh_0051	COG0530	calcium, potassium:sodium antiporter activity
LC1Nh_0053	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LC1Nh_0056	COG0022	dehydrogenase e1 component
LC1Nh_0059	COG1042	CoA-binding domain protein
LC1Nh_0059	COG0045	succinate-CoA ligase (ADP-forming) activity
LC1Nh_0059	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LC1Nh_0063	COG0281	malic enzyme
LC1Nh_0068	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LC1Nh_0070	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LC1Nh_0075	COG1605	Chorismate mutase
LC1Nh_0075	COG0077	Prephenate dehydratase
LC1Nh_0076	COG0436	Aminotransferase
LC1Nh_0077	COG0287	Prephenate dehydrogenase
LC1Nh_0077	COG1605	Chorismate mutase
LC1Nh_0080	COG0551	DNA topoisomerase type I activity
LC1Nh_0080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LC1Nh_0089	COG0430	RNA-3'-phosphate cyclase activity
LC1Nh_0090	COG0071	Belongs to the small heat shock protein (HSP20) family
LC1Nh_0094	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LC1Nh_0100	COG0081	regulation of translation
LC1Nh_0101	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LC1Nh_0105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LC1Nh_0106	COG0544	peptidyl-prolyl cis-trans isomerase activity
LC1Nh_0108	COG0495	leucyl-tRNA aminoacylation
LC1Nh_0109	COG2894	cell division
LC1Nh_0110	COG2894	cell division
LC1Nh_0118	COG0166	Belongs to the GPI family
LC1Nh_0120	COG0297	glycogen (starch) synthase activity
LC1Nh_0133	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LC1Nh_0134	COG0438	transferase activity, transferring glycosyl groups
LC1Nh_0139	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LC1Nh_0139	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LC1Nh_0141	COG1056	cytidyltransferase-related domain
LC1Nh_0141	COG1051	belongs to the nudix hydrolase family
LC1Nh_0149	COG1830	Aldolase
LC1Nh_0150	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LC1Nh_0153	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LC1Nh_0155	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LC1Nh_0157	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LC1Nh_0158	COG0537	adenosine 5'-monophosphoramidase activity
LC1Nh_0159	COG1404	Belongs to the peptidase S8 family
LC1Nh_0161	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LC1Nh_0166	COG1196	nuclear chromosome segregation
LC1Nh_0166	COG1196	nuclear chromosome segregation
LC1Nh_0169	COG0017	Asparaginyl-tRNA synthetase
LC1Nh_0180	COG1940	carbohydrate kinase activity
LC1Nh_0180	COG1846	Transcriptional regulator
LC1Nh_0187	COG0423	glycine-tRNA ligase activity
LC1Nh_0188	COG0126	phosphoglycerate kinase activity
LC1Nh_0190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LC1Nh_0192	COG0180	Tryptophanyl-tRNA synthetase
LC1Nh_0194	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LC1Nh_0195	COG0072	phenylalanine-tRNA ligase activity
LC1Nh_0196	COG1983	PspC domain protein
LC1Nh_0198	COG0105	UTP biosynthetic process
LC1Nh_0204	COG0585	pseudouridine synthase activity
LC1Nh_0206	COG1215	transferase activity, transferring glycosyl groups
LC1Nh_0208	COG0463	Glycosyl transferase, family 2
LC1Nh_0221	COG0714	Associated with various cellular activities
LC1Nh_0230	COG2894	cell division
LC1Nh_0232	COG0574	Belongs to the PEP-utilizing enzyme family
LC1Nh_0232	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LC1Nh_0238	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LC1Nh_0242	COG1234	tRNA 3'-trailer cleavage
LC1Nh_0248	COG0438	transferase activity, transferring glycosyl groups
LC1Nh_0250	COG1078	dGTPase activity
LC1Nh_0256	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LC1Nh_0256	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LC1Nh_0257	COG3291	Pkd domain containing protein
LC1Nh_0257	COG4412	M6 family metalloprotease domain protein
LC1Nh_0260	COG2151	metal-sulfur cluster biosynthetic enzyme
LC1Nh_0263	COG0534	Mate efflux family protein
LC1Nh_0264	COG3976	FMN-binding domain protein
LC1Nh_0264	COG1053	succinate dehydrogenase
LC1Nh_0264	COG0431	NADPH-dependent FMN reductase
LC1Nh_0265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LC1Nh_0267	COG0396	ATPase activity
LC1Nh_0270	COG1199	ATP-dependent helicase activity
LC1Nh_0279	COG0052	Belongs to the universal ribosomal protein uS2 family
LC1Nh_0282	COG0148	phosphopyruvate hydratase activity
LC1Nh_0295	COG1051	belongs to the nudix hydrolase family
LC1Nh_0304	COG2890	protein-(glutamine-N5) methyltransferase activity
LC1Nh_0314	COG4555	ABC transporter
LC1Nh_0318	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LC1Nh_0326	COG0252	asparaginase activity
LC1Nh_0331	COG3046	protein related to deoxyribodipyrimidine photolyase
LC1Nh_0333	COG0778	Nitroreductase
LC1Nh_0342	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LC1Nh_0357	COG2255	four-way junction helicase activity
LC1Nh_0362	COG3118	belongs to the thioredoxin family
LC1Nh_0365	COG0668	transmembrane transport
LC1Nh_0366	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LC1Nh_0368	COG1201	RNA secondary structure unwinding
LC1Nh_0374	COG0084	hydrolase, TatD family'
LC1Nh_0375	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
LC1Nh_0376	COG0717	Belongs to the dCTP deaminase family
LC1Nh_0387	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LC1Nh_0387	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LC1Nh_0396	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LC1Nh_0405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LC1Nh_0410	COG3613	nucleoside 2-deoxyribosyltransferase
LC1Nh_0411	COG0215	cysteine-tRNA ligase activity
LC1Nh_0412	COG0406	alpha-ribazole phosphatase activity
LC1Nh_0414	COG0307	riboflavin synthase, alpha
LC1Nh_0433	COG0805	protein transport
LC1Nh_0442	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LC1Nh_0446	COG0504	CTP synthase activity
LC1Nh_0447	COG2813	Specifically methylates the guanine in position
LC1Nh_0460	COG0442	prolyl-tRNA aminoacylation
LC1Nh_0465	COG0402	S-adenosylhomocysteine deaminase activity
LC1Nh_0467	COG4948	Mandelate Racemase Muconate Lactonizing
LC1Nh_0475	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LC1Nh_0476	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LC1Nh_0480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LC1Nh_0488	COG2133	pyrroloquinoline quinone binding
LC1Nh_0498	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LC1Nh_0507	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LC1Nh_0509	COG0492	ferredoxin-NADP+ reductase activity
LC1Nh_0511	COG1051	belongs to the nudix hydrolase family
LC1Nh_0514	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LC1Nh_0516	COG1131	(ABC) transporter
LC1Nh_0521	COG0442	prolyl-tRNA aminoacylation
LC1Nh_0526	COG0750	zinc metalloprotease
LC1Nh_0532	COG2155	Conserved Protein
LC1Nh_0536	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LC1Nh_0539	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LC1Nh_0540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LC1Nh_0541	COG1522	sequence-specific DNA binding
LC1Nh_0548	COG1704	LemA family
LC1Nh_0549	COG0501	Belongs to the peptidase M48B family
LC1Nh_0554	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LC1Nh_0558	COG1185	polyribonucleotide nucleotidyltransferase activity
LC1Nh_0559	COG1185	polyribonucleotide nucleotidyltransferase activity
LC1Nh_0560	COG1185	polyribonucleotide nucleotidyltransferase activity
LC1Nh_0568	COG0037	tRNA processing
LC1Nh_0574	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LC1Nh_0579	COG0321	lipoyl(octanoyl) transferase activity
LC1Nh_0579	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LC1Nh_0580	COG0154	amidase activity
LC1Nh_0585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LC1Nh_0604	COG0210	DNA helicase
LC1Nh_0605	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LC1Nh_0607	COG0656	L-ascorbic acid biosynthetic process
LC1Nh_0610	COG0589	response to stress
LC1Nh_0615	COG1968	undecaprenyl-diphosphatase activity
LC1Nh_0619	COG0124	histidyl-tRNA synthetase
LC1Nh_0643	COG1793	dna ligase
LC1Nh_0643	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LC1Nh_0648	COG1278	Cold shock
LC1Nh_0652	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LC1Nh_0658	COG0552	protein localization to endoplasmic reticulum
LC1Nh_0673	COG0483	inositol monophosphate 1-phosphatase activity
LC1Nh_0686	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LC1Nh_0686	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LC1Nh_0688	COG1573	uracil-dna glycosylase
LC1Nh_0691	COG2154	pterin-4-alpha-carbinolamine dehydratase
LC1Nh_0696	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LC1Nh_0699	COG0330	HflC and HflK could
LC1Nh_0701	COG1476	TRANSCRIPTIONal
LC1Nh_0710	COG1126	abc transporter atp-binding protein
LC1Nh_0719	COG1733	regulation of RNA biosynthetic process
LC1Nh_0722	COG0446	pyridine nucleotide-disulphide oxidoreductase
LC1Nh_0746	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LC1Nh_0763	COG1131	(ABC) transporter
LC1Nh_0772	COG0475	glutathione-regulated potassium exporter activity
LC1Nh_0772	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LC1Nh_0773	COG0009	L-threonylcarbamoyladenylate synthase
LC1Nh_0776	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LC1Nh_0780	COG1185	polyribonucleotide nucleotidyltransferase activity
LC1Nh_0805	COG0714	Associated with various cellular activities
LC1Nh_0814	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LC1Nh_0815	COG1733	regulation of RNA biosynthetic process
LC1Nh_0829	COG1394	ATPase activity, coupled to movement of substances
LC1Nh_0830	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
LC1Nh_0831	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
LC1Nh_0836	COG1269	ATP hydrolysis coupled proton transport
LC1Nh_0838	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
LC1Nh_0849	COG0616	signal peptide processing
LC1Nh_0850	COG1378	Sugar-specific transcriptional regulator TrmB
LC1Nh_0852	COG1793	dna ligase
LC1Nh_0860	COG2154	pterin-4-alpha-carbinolamine dehydratase
LC1Nh_0871	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LC1Nh_0882	COG0494	nUDIX hydrolase
LC1Nh_0888	COG2003	Belongs to the UPF0758 family
LC1Nh_0890	COG0085	RNA polymerase activity
LC1Nh_0893	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LC1Nh_0897	COG0049	tRNA binding
LC1Nh_0899	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LC1Nh_0904	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LC1Nh_0906	COG0051	transcription antitermination factor activity, RNA binding
LC1Nh_0909	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LC1Nh_0922	COG2264	protein methyltransferase activity
LC1Nh_0941	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LC1Nh_0954	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LC1Nh_0957	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LC1Nh_0973	COG1733	regulation of RNA biosynthetic process
LC1Nh_0990	COG0010	Belongs to the arginase family
LC1Nh_1003	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LC1Nh_1028	COG0596	Alpha beta hydrolase
LC1Nh_1030	COG0095	Lipoate-protein ligase
LC1Nh_1031	COG2096	Adenosyltransferase
LC1Nh_1032	COG0045	succinate-CoA ligase (ADP-forming) activity
LC1Nh_1034	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LC1Nh_1042	COG0537	adenosine 5'-monophosphoramidase activity
LC1Nh_1048	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LC1Nh_1049	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LC1Nh_1073	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LC1Nh_1074	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LC1Nh_1075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LC1Nh_1076	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LC1Nh_1091	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LC1Nh_1094	COG0200	Binds to the 23S rRNA
LC1Nh_1101	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LC1Nh_1106	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LC1Nh_1107	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LC1Nh_1113	COG0023	Translation Initiation Factor
LC1Nh_1114	COG0255	Belongs to the universal ribosomal protein uL29 family
LC1Nh_1115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LC1Nh_1117	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LC1Nh_1118	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LC1Nh_1119	COG0089	rRNA binding
LC1Nh_1121	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LC1Nh_1127	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LC1Nh_1127	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LC1Nh_1146	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LC1Nh_1149	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LC1Nh_1152	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LC1Nh_1157	COG1940	carbohydrate kinase activity
LC1Nh_1168	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LC1Nh_1168	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LC1Nh_1169	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LC1Nh_1170	COG1028	Short-chain dehydrogenase reductase Sdr
LC1Nh_1187	COG2244	polysaccharide biosynthetic process
LC1Nh_1188	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LC1Nh_1189	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LC1Nh_1194	COG1216	Glycosyl transferase, family 2
LC1Nh_1194	COG0463	Glycosyl transferase, family 2