locus-tag	class	description
DVJ83_00015	COG0438	transferase activity, transferring glycosyl groups
DVJ83_00025	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DVJ83_00035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DVJ83_00040	COG0174	glutamine synthetase
DVJ83_00055	COG1968	undecaprenyl-diphosphatase activity
DVJ83_00065	COG0811	peptide transport
DVJ83_00105	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DVJ83_00120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DVJ83_00135	COG1796	DNA polymerase
DVJ83_00135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DVJ83_00145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DVJ83_00165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DVJ83_00180	COG0037	tRNA processing
DVJ83_00195	COG3012	SEC-C Motif Domain Protein
DVJ83_00200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DVJ83_00220	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DVJ83_00235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DVJ83_00245	COG0259	pyridoxamine-phosphate oxidase activity
DVJ83_00250	COG0493	'glutamate synthase
DVJ83_00255	COG1760	l-serine dehydratase
DVJ83_00280	COG1307	EDD domain protein, DegV family
DVJ83_00290	COG0167	dihydroorotate dehydrogenase activity
DVJ83_00295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DVJ83_00300	COG0737	Belongs to the 5'-nucleotidase family
DVJ83_00310	COG1959	2 iron, 2 sulfur cluster binding
DVJ83_00320	COG0284	orotidine-5'-phosphate decarboxylase activity
DVJ83_00340	COG1116	anion transmembrane transporter activity
DVJ83_00345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DVJ83_00355	COG0189	ligase activity
DVJ83_00375	COG1136	(ABC) transporter
DVJ83_00380	COG1902	pentaerythritol trinitrate reductase activity
DVJ83_00400	COG2873	o-acetylhomoserine
DVJ83_00455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DVJ83_00465	COG1253	flavin adenine dinucleotide binding
DVJ83_00480	COG0495	leucyl-tRNA aminoacylation
DVJ83_00500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DVJ83_00525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DVJ83_00530	COG2151	metal-sulfur cluster biosynthetic enzyme
DVJ83_00540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DVJ83_00570	COG0113	porphobilinogen synthase activity
DVJ83_00590	COG0765	amino acid transport
DVJ83_00595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DVJ83_00600	COG3842	ATPase activity
DVJ83_00605	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DVJ83_00615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DVJ83_00620	COG0706	membrane insertase activity
DVJ83_00625	COG1309	transcriptional regulator
DVJ83_00650	COG0330	HflC and HflK could
DVJ83_00655	COG1585	Membrane protein implicated in regulation of membrane protease activity
DVJ83_00670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DVJ83_00695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DVJ83_00710	COG0826	peptidase U32
DVJ83_00715	COG0203	ribosomal protein L17
DVJ83_00720	COG0202	RNA polymerase activity
DVJ83_00725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DVJ83_00730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DVJ83_00735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DVJ83_00740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DVJ83_00745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DVJ83_00755	COG0559	Belongs to the binding-protein-dependent transport system permease family
DVJ83_00765	COG0411	ABC transporter
DVJ83_00770	COG0410	ABC transporter
DVJ83_00775	COG0563	adenylate kinase activity
DVJ83_00780	COG0201	protein transport
DVJ83_00785	COG0200	Binds to the 23S rRNA
DVJ83_00790	COG1841	ribosomal large subunit assembly
DVJ83_00795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DVJ83_00800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DVJ83_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DVJ83_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DVJ83_00815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DVJ83_00825	COG0396	ATPase activity
DVJ83_00830	COG0719	Fe-S assembly protein
DVJ83_00835	COG0719	Fe-S assembly protein
DVJ83_00870	COG0616	signal peptide processing
DVJ83_00880	COG1959	2 iron, 2 sulfur cluster binding
DVJ83_00885	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DVJ83_00890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DVJ83_00895	COG3424	synthase
DVJ83_00910	COG4269	membrane
DVJ83_00915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DVJ83_00935	COG0584	glycerophosphoryl diester phosphodiesterase
DVJ83_00945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DVJ83_00985	COG2094	Belongs to the DNA glycosylase MPG family
DVJ83_00990	COG3214	Protein conserved in bacteria
DVJ83_01005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DVJ83_01015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DVJ83_01025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DVJ83_01030	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DVJ83_01035	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DVJ83_01065	COG0423	glycine-tRNA ligase activity
DVJ83_01085	COG1164	Oligoendopeptidase f
DVJ83_01090	COG0704	Plays a role in the regulation of phosphate uptake
DVJ83_01095	COG1132	(ABC) transporter
DVJ83_01100	COG1132	(ABC) transporter
DVJ83_01125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DVJ83_01130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DVJ83_01135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DVJ83_01140	COG0250	Participates in transcription elongation, termination and antitermination
DVJ83_01145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DVJ83_01150	COG0081	regulation of translation
DVJ83_01155	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DVJ83_01160	COG0222	ribosome binding
DVJ83_01165	COG2308	Evidence 4 Homologs of previously reported genes of
DVJ83_01175	COG1192	Involved in chromosome partitioning
DVJ83_01190	COG4762	Protein conserved in bacteria
DVJ83_01210	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVJ83_01240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DVJ83_01245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVJ83_01265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DVJ83_01350	COG1494	fructose-1,6-bisphosphatase
DVJ83_01360	COG0336	Belongs to the RNA methyltransferase TrmD family
DVJ83_01365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DVJ83_01370	COG1837	Belongs to the UPF0109 family
DVJ83_01375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DVJ83_01390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DVJ83_01395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DVJ83_01425	COG0753	catalase activity
DVJ83_01435	COG0416	fatty acid biosynthetic process
DVJ83_01440	COG0668	transmembrane transport
DVJ83_01450	COG1305	Transglutaminase-like
DVJ83_01460	COG0585	pseudouridine synthase activity
DVJ83_01480	COG1307	EDD domain protein, DegV family
DVJ83_01490	COG1435	thymidine kinase activity
DVJ83_01495	COG0539	negative regulation of cytoplasmic translation
DVJ83_01505	COG0492	ferredoxin-NADP+ reductase activity
DVJ83_01515	COG0702	epimerase
DVJ83_01525	COG1193	negative regulation of DNA recombination
DVJ83_01540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DVJ83_01545	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DVJ83_01550	COG0740	serine-type endopeptidase activity
DVJ83_01580	COG0778	Nitroreductase
DVJ83_01595	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DVJ83_01615	COG1404	Belongs to the peptidase S8 family
DVJ83_01660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DVJ83_01665	COG0544	peptidyl-prolyl cis-trans isomerase activity
DVJ83_01670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DVJ83_01675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DVJ83_01680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DVJ83_01690	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_01695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVJ83_01700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DVJ83_01705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DVJ83_01725	COG2390	Transcriptional regulator
DVJ83_01735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DVJ83_01740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DVJ83_01765	COG0419	ATPase involved in DNA repair
DVJ83_01770	COG0420	3'-5' exonuclease activity
DVJ83_01795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DVJ83_01810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DVJ83_01835	COG1556	Lactate utilization protein
DVJ83_01840	COG1139	Iron-sulfur cluster binding protein
DVJ83_01845	COG0247	lactate metabolic process
DVJ83_01850	COG1620	l-lactate permease
DVJ83_01855	COG2186	Transcriptional regulator
DVJ83_01860	COG1307	EDD domain protein, DegV family
DVJ83_01865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DVJ83_01885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DVJ83_01900	COG0686	Belongs to the AlaDH PNT family
DVJ83_01915	COG0237	dephospho-CoA kinase activity
DVJ83_01935	COG0667	Aldo Keto reductase
DVJ83_01940	COG2389	metal-binding protein
DVJ83_01990	COG0517	IMP dehydrogenase activity
DVJ83_01990	COG0516	GMP reductase activity
DVJ83_02005	COG2364	Membrane
DVJ83_02010	COG0519	Catalyzes the synthesis of GMP from XMP
DVJ83_02010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DVJ83_02025	COG4948	Mandelate Racemase Muconate Lactonizing
DVJ83_02050	COG0275	rRNA processing
DVJ83_02055	COG2001	Belongs to the MraZ family
DVJ83_02060	COG2363	Small membrane protein
DVJ83_02070	COG0009	L-threonylcarbamoyladenylate synthase
DVJ83_02075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DVJ83_02095	COG1764	response to oxidative stress
DVJ83_02100	COG0154	amidase activity
DVJ83_02125	COG0515	serine threonine protein kinase
DVJ83_02125	COG2815	serine threonine protein kinase
DVJ83_02135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DVJ83_02145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DVJ83_02160	COG2362	D-Aminopeptidase
DVJ83_02175	COG2259	Doxx family
DVJ83_02190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DVJ83_02200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DVJ83_02205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DVJ83_02230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DVJ83_02235	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DVJ83_02250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVJ83_02255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DVJ83_02255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DVJ83_02270	COG4294	response to UV
DVJ83_02285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DVJ83_02300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DVJ83_02320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DVJ83_02325	COG0509	glycine decarboxylation via glycine cleavage system
DVJ83_02330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DVJ83_02330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DVJ83_02350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DVJ83_02355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DVJ83_02365	COG0195	Participates in both transcription termination and antitermination
DVJ83_02370	COG0779	Required for maturation of 30S ribosomal subunits
DVJ83_02375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DVJ83_02390	COG0564	pseudouridine synthase activity
DVJ83_02400	COG0754	glutathionylspermidine amidase activity
DVJ83_02420	COG0473	3-isopropylmalate dehydrogenase activity
DVJ83_02425	COG0066	3-isopropylmalate dehydratase activity
DVJ83_02445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DVJ83_02465	COG0210	DNA helicase
DVJ83_02480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DVJ83_02490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DVJ83_02500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DVJ83_02505	COG0512	Glutamine amidotransferase of anthranilate synthase
DVJ83_02520	COG2514	catechol 2,3-dioxygenase activity
DVJ83_02530	COG0482	sulfurtransferase activity
DVJ83_02535	COG0019	diaminopimelate decarboxylase activity
DVJ83_02545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVJ83_02555	COG1185	polyribonucleotide nucleotidyltransferase activity
DVJ83_02560	COG0850	regulation of cytokinetic process
DVJ83_02575	COG1573	uracil-dna glycosylase
DVJ83_02610	COG1755	Isoprenylcysteine carboxyl methyltransferase
DVJ83_02630	COG0166	Belongs to the GPI family
DVJ83_02645	COG0737	Belongs to the 5'-nucleotidase family
DVJ83_02655	COG0277	FAD linked oxidase domain protein
DVJ83_02660	COG0247	lactate metabolic process
DVJ83_02665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DVJ83_02670	COG0574	Belongs to the PEP-utilizing enzyme family
DVJ83_02670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DVJ83_02675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DVJ83_02700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DVJ83_02705	COG0747	negative chemotaxis
DVJ83_02720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DVJ83_02720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DVJ83_02730	COG0277	FAD linked oxidase domain protein
DVJ83_02745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DVJ83_02800	COG0683	leucine binding
DVJ83_02805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DVJ83_02820	COG0542	response to heat
DVJ83_02845	COG0017	Asparaginyl-tRNA synthetase
DVJ83_02870	COG0395	ABC-type sugar transport system, permease component
DVJ83_02875	COG1175	transmembrane transport
DVJ83_02900	COG1250	3-hydroxyacyl-CoA dehydrogenase
DVJ83_02925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DVJ83_02935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DVJ83_02940	COG0726	polysaccharide deacetylase
DVJ83_02960	COG1309	transcriptional regulator
DVJ83_02965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DVJ83_02970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVJ83_02970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVJ83_02975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DVJ83_02980	COG1304	FMN binding
DVJ83_02990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DVJ83_02995	COG3706	GGDEF domain
DVJ83_03010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DVJ83_03020	COG0180	Tryptophanyl-tRNA synthetase
DVJ83_03065	COG0612	Peptidase, M16
DVJ83_03075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DVJ83_03080	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DVJ83_03085	COG1914	H( )-stimulated, divalent metal cation uptake system
DVJ83_03110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DVJ83_03120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DVJ83_03125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DVJ83_03130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DVJ83_03140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DVJ83_03165	COG0688	phosphatidylethanolamine metabolic process
DVJ83_03170	COG0504	CTP synthase activity
DVJ83_03175	COG3973	AAA domain
DVJ83_03180	COG0747	negative chemotaxis
DVJ83_03185	COG0601	transmembrane transport
DVJ83_03190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVJ83_03210	COG3437	response regulator, receiver
DVJ83_03220	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DVJ83_03225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DVJ83_03230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DVJ83_03235	COG1597	lipid kinase activity
DVJ83_03245	COG2197	response regulator
DVJ83_03270	COG0438	transferase activity, transferring glycosyl groups
DVJ83_03275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DVJ83_03285	COG0793	Belongs to the peptidase S41A family
DVJ83_03290	COG2884	Cell division ATP-binding protein ftsE
DVJ83_03295	COG2177	Part of the ABC transporter FtsEX involved in
DVJ83_03315	COG2032	superoxide dismutase activity
DVJ83_03335	COG1960	acyl-CoA dehydrogenase activity
DVJ83_03345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DVJ83_03355	COG0538	isocitrate dehydrogenase activity
DVJ83_03360	COG1764	response to oxidative stress
DVJ83_03365	COG2267	carboxylic ester hydrolase activity
DVJ83_03380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DVJ83_03395	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DVJ83_03400	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DVJ83_03400	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DVJ83_03415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DVJ83_03420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVJ83_03430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DVJ83_03435	COG2264	protein methyltransferase activity
DVJ83_03450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DVJ83_03455	COG4636	protein conserved in cyanobacteria
DVJ83_03465	COG0028	Belongs to the TPP enzyme family
DVJ83_03480	COG0052	Belongs to the universal ribosomal protein uS2 family
DVJ83_03485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DVJ83_03490	COG0528	UMP kinase activity
DVJ83_03495	COG0233	cytoplasmic translational termination
DVJ83_03500	COG0575	Belongs to the CDS family
DVJ83_03505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DVJ83_03510	COG0750	zinc metalloprotease
DVJ83_03515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVJ83_03520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVJ83_03525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVJ83_03530	COG0649	NAD binding
DVJ83_03535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DVJ83_03540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DVJ83_03545	COG1034	ATP synthesis coupled electron transport
DVJ83_03550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DVJ83_03555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVJ83_03560	COG0839	Belongs to the complex I subunit 6 family
DVJ83_03565	COG0713	ATP synthesis coupled electron transport
DVJ83_03570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DVJ83_03575	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVJ83_03580	COG1007	ATP synthesis coupled electron transport
DVJ83_03595	COG0604	alcohol dehydrogenase
DVJ83_03605	COG1250	3-hydroxyacyl-CoA dehydrogenase
DVJ83_03605	COG1024	Enoyl-CoA hydratase
DVJ83_03635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DVJ83_03660	COG0497	DNA recombination
DVJ83_03670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DVJ83_03680	COG1842	Phage shock protein A
DVJ83_03690	COG0582	viral genome integration into host DNA
DVJ83_03750	COG1203	CRISPR-associated helicase, Cas3
DVJ83_03755	COG2337	Toxic component of a toxin-antitoxin (TA) module
DVJ83_03765	COG1518	maintenance of DNA repeat elements
DVJ83_03805	COG0753	catalase activity
DVJ83_03840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DVJ83_03860	COG0714	Associated with various cellular activities
DVJ83_03890	COG1403	HNH endonuclease
DVJ83_03905	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
DVJ83_03915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DVJ83_03920	COG1960	acyl-CoA dehydrogenase activity
DVJ83_03935	COG2814	Major facilitator Superfamily
DVJ83_03940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DVJ83_03955	COG0791	NLP P60 protein
DVJ83_03985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DVJ83_03995	COG3383	formate dehydrogenase (NAD+) activity
DVJ83_04010	COG0384	phenazine biosynthesis protein PhzF
DVJ83_04020	COG1472	Belongs to the glycosyl hydrolase 3 family
DVJ83_04030	COG1653	transport
DVJ83_04035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DVJ83_04040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DVJ83_04045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DVJ83_04050	COG0149	triose-phosphate isomerase activity
DVJ83_04060	COG0126	phosphoglycerate kinase activity
DVJ83_04080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DVJ83_04090	COG0124	histidyl-tRNA synthetase
DVJ83_04095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DVJ83_04105	COG2267	carboxylic ester hydrolase activity
DVJ83_04115	COG0322	excinuclease ABC activity
DVJ83_04130	COG0791	NLP P60 protein
DVJ83_04155	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DVJ83_04160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DVJ83_04165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DVJ83_04195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DVJ83_04195	COG1754	DNA topoisomerase type I activity
DVJ83_04205	COG0366	Alpha amylase catalytic
DVJ83_04230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DVJ83_04245	COG0012	GTP binding
DVJ83_04270	COG1040	competence protein
DVJ83_04290	COG0406	alpha-ribazole phosphatase activity
DVJ83_04300	COG0142	geranyltranstransferase activity
DVJ83_04320	COG2045	Belongs to the ComB family
DVJ83_04325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DVJ83_04340	COG2267	carboxylic ester hydrolase activity
DVJ83_04385	COG0471	metal ion transport
DVJ83_04385	COG3273	potassium ion transport
DVJ83_04390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVJ83_04420	COG0745	RESPONSE REGULATOR receiver
DVJ83_04425	COG1660	Displays ATPase and GTPase activities
DVJ83_04430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DVJ83_04445	COG3870	Protein conserved in bacteria
DVJ83_04450	COG0484	heat shock protein binding
DVJ83_04460	COG0134	indole-3-glycerol-phosphate synthase activity
DVJ83_04465	COG0681	Belongs to the peptidase S26 family
DVJ83_04470	COG0183	Belongs to the thiolase family
DVJ83_04480	COG0151	Belongs to the GarS family
DVJ83_04490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DVJ83_04490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DVJ83_04495	COG1660	Displays ATPase and GTPase activities
DVJ83_04500	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DVJ83_04540	COG2217	Heavy metal translocating P-type atpase
DVJ83_04565	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DVJ83_04570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DVJ83_04590	COG1346	cytolysis
DVJ83_04595	COG1380	Effector of murein hydrolase LrgA
DVJ83_04600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DVJ83_04605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DVJ83_04620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DVJ83_04685	COG4221	oxidoreductase activity
DVJ83_04690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DVJ83_04705	COG1196	nuclear chromosome segregation
DVJ83_04710	COG0024	Methionine aminopeptidase
DVJ83_04730	COG2137	regulation of response to DNA damage stimulus
DVJ83_04735	COG0268	Binds directly to 16S ribosomal RNA
DVJ83_04740	COG0793	Belongs to the peptidase S41A family
DVJ83_04745	COG0477	Major facilitator Superfamily
DVJ83_04755	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DVJ83_04760	COG1177	transmembrane transport
DVJ83_04765	COG1176	ABC-type spermidine putrescine transport system, permease component I
DVJ83_04770	COG3842	ATPase activity
DVJ83_04780	COG0785	Cytochrome C biogenesis protein
DVJ83_04795	COG2354	Protein conserved in bacteria
DVJ83_04800	COG5006	permease, DMT superfamily
DVJ83_04805	COG0228	four-way junction DNA binding
DVJ83_04815	COG0521	Mo-molybdopterin cofactor biosynthetic process
DVJ83_04820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DVJ83_04825	COG0747	negative chemotaxis
DVJ83_04830	COG0514	ATP-dependent DNA helicase (RecQ)
DVJ83_04835	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DVJ83_04840	COG1692	metallophosphoesterase
DVJ83_04845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DVJ83_04850	COG0460	homoserine dehydrogenase
DVJ83_04855	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DVJ83_04860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DVJ83_04865	COG0632	four-way junction helicase activity
DVJ83_04880	COG0778	Nitroreductase
DVJ83_04885	COG0017	Asparaginyl-tRNA synthetase
DVJ83_04895	COG0442	prolyl-tRNA aminoacylation
DVJ83_04925	COG1960	acyl-CoA dehydrogenase activity
DVJ83_04950	COG0045	succinate-CoA ligase (ADP-forming) activity
DVJ83_04955	COG0006	proline dipeptidase activity
DVJ83_04960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DVJ83_04985	COG4221	oxidoreductase activity
DVJ83_04990	COG2301	Belongs to the HpcH HpaI aldolase family
DVJ83_05095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DVJ83_05110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DVJ83_05115	COG0825	malonyl-CoA metabolic process
DVJ83_05150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DVJ83_05155	COG0590	tRNA wobble adenosine to inosine editing
DVJ83_05155	COG0037	tRNA processing
DVJ83_05160	COG0424	maF-like protein
DVJ83_05165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DVJ83_05200	COG0693	protein deglycase activity
DVJ83_05225	COG0617	tRNA 3'-terminal CCA addition
DVJ83_05240	COG0628	permease
DVJ83_05265	COG0494	nUDIX hydrolase
DVJ83_05270	COG3956	TIGRFAM MazG family protein
DVJ83_05315	COG5002	protein histidine kinase activity
DVJ83_05315	COG2205	protein histidine kinase activity
DVJ83_05315	COG0784	Response regulator, receiver
DVJ83_05320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DVJ83_05325	COG5412	phage tail tape measure protein
DVJ83_05345	COG1950	PFAM Membrane protein of
DVJ83_05350	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DVJ83_05360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DVJ83_05370	COG1024	Enoyl-CoA hydratase
DVJ83_05375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DVJ83_05380	COG0475	glutathione-regulated potassium exporter activity
DVJ83_05385	COG0490	domain, Protein
DVJ83_05395	COG1605	Chorismate mutase
DVJ83_05395	COG0077	Prephenate dehydratase
DVJ83_05405	COG0251	oxidation-reduction process
DVJ83_05410	COG0481	GTPase activity
DVJ83_05460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DVJ83_05465	COG0129	dihydroxy-acid dehydratase activity
DVJ83_05470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DVJ83_05485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DVJ83_05495	COG3206	protein involved in exopolysaccharide biosynthesis
DVJ83_05500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DVJ83_05505	COG0287	Prephenate dehydrogenase
DVJ83_05515	COG3426	butyrate kinase activity
DVJ83_05530	COG4956	integral membrane protein (PIN domain superfamily)
DVJ83_05535	COG0542	response to heat
DVJ83_05550	COG0071	Belongs to the small heat shock protein (HSP20) family
DVJ83_05555	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DVJ83_05560	COG0540	Belongs to the ATCase OTCase family
DVJ83_05565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DVJ83_05570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DVJ83_05575	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DVJ83_05615	COG3591	Belongs to the peptidase S1B family
DVJ83_05615	COG1864	DNA RNA non-specific endonuclease
DVJ83_05630	COG0179	Fumarylacetoacetate (FAA) hydrolase
DVJ83_05635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DVJ83_05640	COG0066	3-isopropylmalate dehydratase activity
DVJ83_05655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DVJ83_05660	COG2720	vancomycin resistance protein
DVJ83_05665	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_05670	COG0537	adenosine 5'-monophosphoramidase activity
DVJ83_05675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVJ83_05685	COG0513	Belongs to the DEAD box helicase family
DVJ83_05690	COG0154	amidase activity
DVJ83_05695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DVJ83_05715	COG4251	negative regulation of phosphorylation
DVJ83_05720	COG0789	Transcriptional regulator
DVJ83_05740	COG0860	N-Acetylmuramoyl-L-alanine amidase
DVJ83_05755	COG0488	(ABC) transporter
DVJ83_05790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVJ83_05795	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DVJ83_05800	COG1126	abc transporter atp-binding protein
DVJ83_05820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DVJ83_05830	COG0339	signal peptide processing
DVJ83_05840	COG2359	stage V sporulation protein S
DVJ83_05845	COG1063	alcohol dehydrogenase
DVJ83_05855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DVJ83_05870	COG0569	domain protein
DVJ83_05875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DVJ83_05885	COG0116	Belongs to the methyltransferase superfamily
DVJ83_05885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DVJ83_05890	COG0215	cysteine-tRNA ligase activity
DVJ83_05895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVJ83_05905	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DVJ83_05905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DVJ83_05910	COG0473	3-isopropylmalate dehydrogenase activity
DVJ83_05920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DVJ83_05930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DVJ83_05935	COG0445	tRNA wobble uridine modification
DVJ83_05940	COG0564	pseudouridine synthase activity
DVJ83_05945	COG1192	Involved in chromosome partitioning
DVJ83_05955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DVJ83_05965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DVJ83_05975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DVJ83_05985	COG0318	PFAM AMP-dependent synthetase and ligase
DVJ83_05995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DVJ83_06020	COG0346	lactoylglutathione lyase activity
DVJ83_06035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DVJ83_06045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DVJ83_06065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DVJ83_06075	COG1218	3'(2'),5'-bisphosphate nucleotidase
DVJ83_06080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DVJ83_06100	COG0683	leucine binding
DVJ83_06105	COG0494	nUDIX hydrolase
DVJ83_06110	COG2318	DinB family
DVJ83_06130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DVJ83_06140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DVJ83_06160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DVJ83_06185	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DVJ83_06195	COG0196	riboflavin kinase activity
DVJ83_06200	COG0494	nUDIX hydrolase
DVJ83_06205	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DVJ83_06210	COG2076	Multidrug Resistance protein
DVJ83_06215	COG2076	Multidrug Resistance protein
DVJ83_06225	COG2346	COG2346, Truncated hemoglobins
DVJ83_06230	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DVJ83_06230	COG1605	Chorismate mutase
DVJ83_06245	COG0489	protein tyrosine kinase activity
DVJ83_06250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVJ83_06270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DVJ83_06275	COG0517	IMP dehydrogenase activity
DVJ83_06290	COG2197	response regulator
DVJ83_06300	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DVJ83_06315	COG1994	Peptidase M50
DVJ83_06320	COG3706	GGDEF domain
DVJ83_06330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DVJ83_06335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DVJ83_06355	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DVJ83_06360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DVJ83_06380	COG2086	electron transfer activity
DVJ83_06415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DVJ83_06425	COG0564	pseudouridine synthase activity
DVJ83_06440	COG0601	transmembrane transport
DVJ83_06465	COG2009	succinate dehydrogenase
DVJ83_06475	COG1053	succinate dehydrogenase
DVJ83_06485	COG1252	NADH dehydrogenase
DVJ83_06510	COG1363	Peptidase, m42
DVJ83_06520	COG3118	belongs to the thioredoxin family
DVJ83_06530	COG0159	tryptophan synthase activity
DVJ83_06535	COG0133	tryptophan synthase activity
DVJ83_06545	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DVJ83_06560	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DVJ83_06565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DVJ83_06570	COG0789	Transcriptional regulator
DVJ83_06590	COG0142	geranyltranstransferase activity
DVJ83_06605	COG1254	Belongs to the acylphosphatase family
DVJ83_06615	COG4555	ABC transporter
DVJ83_06620	COG1668	transmembrane transport
DVJ83_06645	COG0306	phosphate transporter
DVJ83_06655	COG0366	Alpha amylase catalytic
DVJ83_06655	COG1874	Beta-galactosidase
DVJ83_06675	COG1960	acyl-CoA dehydrogenase activity
DVJ83_06700	COG0714	Associated with various cellular activities
DVJ83_06715	COG2813	Specifically methylates the guanine in position
DVJ83_06725	COG0085	RNA polymerase activity
DVJ83_06730	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DVJ83_06735	COG3942	CHAP domain
DVJ83_06735	COG1388	LysM domain
DVJ83_06750	COG1278	Cold shock
DVJ83_06755	COG0187	DNA topoisomerase II activity
DVJ83_06775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DVJ83_06810	COG1187	pseudouridine synthase activity
DVJ83_06825	COG0670	Belongs to the BI1 family
DVJ83_06830	COG2205	protein histidine kinase activity
DVJ83_06835	COG2197	response regulator
DVJ83_06840	COG1490	D-aminoacyl-tRNA deacylase activity
DVJ83_06850	COG1652	LysM domain
DVJ83_06850	COG2823	Periplasmic or secreted lipoprotein
DVJ83_06860	COG1320	monovalent cation:proton antiporter activity
DVJ83_06865	COG2212	antiporter activity
DVJ83_06880	COG1006	Multisubunit Na H antiporter MnhC subunit
DVJ83_06885	COG2111	Na H antiporter
DVJ83_06895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DVJ83_06925	COG2873	o-acetylhomoserine
DVJ83_06930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DVJ83_06950	COG0138	bifunctional purine biosynthesis protein purh
DVJ83_06955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DVJ83_06960	COG0438	transferase activity, transferring glycosyl groups
DVJ83_06965	COG0735	belongs to the Fur family
DVJ83_06980	COG1562	ergosterol biosynthetic process
DVJ83_06990	COG2205	protein histidine kinase activity
DVJ83_06990	COG2202	Pas domain
DVJ83_06995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DVJ83_07010	COG2176	DNA-directed DNA polymerase activity
DVJ83_07025	COG1100	Small GTP-binding protein
DVJ83_07040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DVJ83_07055	COG4942	peptidase
DVJ83_07060	COG2050	protein possibly involved in aromatic compounds catabolism
DVJ83_07070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DVJ83_07075	COG1331	Highly conserved protein containing a thioredoxin domain
DVJ83_07085	COG0697	spore germination
DVJ83_07130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVJ83_07135	COG2224	Isocitrate lyase
DVJ83_07145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DVJ83_07155	COG0254	rRNA binding
DVJ83_07165	COG0402	S-adenosylhomocysteine deaminase activity
DVJ83_07170	COG4326	sporulation control protein
DVJ83_07180	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_07190	COG1381	Involved in DNA repair and RecF pathway recombination
DVJ83_07210	COG0506	proline dehydrogenase activity
DVJ83_07215	COG0456	acetyltransferase
DVJ83_07215	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DVJ83_07220	COG1012	belongs to the aldehyde dehydrogenase family
DVJ83_07250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DVJ83_07255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DVJ83_07260	COG0805	protein transport
DVJ83_07265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DVJ83_07310	COG0673	inositol 2-dehydrogenase activity
DVJ83_07340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVJ83_07355	COG0534	Mate efflux family protein
DVJ83_07360	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DVJ83_07365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DVJ83_07390	COG0494	nUDIX hydrolase
DVJ83_07395	COG3191	aminopeptidase activity
DVJ83_07400	COG0745	RESPONSE REGULATOR receiver
DVJ83_07415	COG2819	hydrolase of the alpha beta superfamily
DVJ83_07420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DVJ83_07425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DVJ83_07430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DVJ83_07435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DVJ83_07440	COG1450	Type ii and iii secretion system protein
DVJ83_07470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DVJ83_07480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DVJ83_07485	COG0321	lipoyl(octanoyl) transferase activity
DVJ83_07505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DVJ83_07525	COG0372	Belongs to the citrate synthase family
DVJ83_07535	COG0456	acetyltransferase
DVJ83_07535	COG1214	PFAM Peptidase M22, glycoprotease
DVJ83_07545	COG0335	large ribosomal subunit rRNA binding
DVJ83_07550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DVJ83_07560	COG2894	cell division
DVJ83_07565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DVJ83_07570	COG2203	Gaf domain
DVJ83_07570	COG2199	diguanylate cyclase activity
DVJ83_07570	COG2200	EAL domain
DVJ83_07575	COG1863	multisubunit Na H antiporter MnhE subunit
DVJ83_07585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DVJ83_07615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVJ83_07620	COG5002	protein histidine kinase activity
DVJ83_07630	COG1438	arginine binding
DVJ83_07670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DVJ83_07670	COG0140	phosphoribosyl-ATP diphosphatase activity
DVJ83_07675	COG0107	imidazoleglycerol-phosphate synthase activity
DVJ83_07685	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_07695	COG1105	Belongs to the carbohydrate kinase PfkB family
DVJ83_07705	COG0366	Alpha amylase catalytic
DVJ83_07710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DVJ83_07710	COG2199	diguanylate cyclase activity
DVJ83_07715	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DVJ83_07720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DVJ83_07735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DVJ83_07750	COG0438	transferase activity, transferring glycosyl groups
DVJ83_07760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DVJ83_07765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DVJ83_07790	COG2342	PFAM TM1410 hypothetical-related protein
DVJ83_07795	COG1394	ATPase activity, coupled to movement of substances
DVJ83_07800	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DVJ83_07805	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DVJ83_07810	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
DVJ83_07815	COG1527	subunit (C
DVJ83_07820	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
DVJ83_07830	COG1269	ATP hydrolysis coupled proton transport
DVJ83_07845	COG0347	Belongs to the P(II) protein family
DVJ83_07855	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DVJ83_07880	COG0505	Belongs to the CarA family
DVJ83_07905	COG0165	Argininosuccinate lyase
DVJ83_07925	COG0137	argininosuccinate synthase activity
DVJ83_07940	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DVJ83_07950	COG2337	Toxic component of a toxin-antitoxin (TA) module
DVJ83_07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVJ83_07980	COG0010	Belongs to the arginase family
DVJ83_07990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DVJ83_07995	COG0746	molybdenum cofactor guanylyltransferase activity
DVJ83_08005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DVJ83_08010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DVJ83_08015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DVJ83_08040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DVJ83_08045	COG0205	6-phosphofructokinase activity
DVJ83_08060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DVJ83_08070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DVJ83_08075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DVJ83_08080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DVJ83_08085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DVJ83_08105	COG0714	Associated with various cellular activities
DVJ83_08115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DVJ83_08135	COG0583	DNA-binding transcription factor activity
DVJ83_08145	COG3665	Urea carboxylase-associated protein
DVJ83_08150	COG4187	Peptidase family M20/M25/M40
DVJ83_08155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVJ83_08175	COG0459	protein refolding
DVJ83_08180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DVJ83_08185	COG3706	GGDEF domain
DVJ83_08195	COG0590	tRNA wobble adenosine to inosine editing
DVJ83_08195	COG0037	tRNA processing
DVJ83_08205	COG0358	DNA primase activity
DVJ83_08220	COG2746	aminoglycoside 3-N-acetyltransferase activity
DVJ83_08235	COG2255	four-way junction helicase activity
DVJ83_08245	COG0297	glycogen (starch) synthase activity
DVJ83_08300	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DVJ83_08315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DVJ83_08370	COG0653	protein targeting
DVJ83_08420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DVJ83_08425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DVJ83_08460	COG2182	Extracellular solute-binding protein
DVJ83_08465	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DVJ83_08465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DVJ83_08485	COG0180	Tryptophanyl-tRNA synthetase
DVJ83_08500	COG1832	CoA-binding protein
DVJ83_08505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DVJ83_08530	COG1960	acyl-CoA dehydrogenase activity
DVJ83_08545	COG2165	general secretion pathway protein
DVJ83_08565	COG0730	response to heat
DVJ83_08570	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_08575	COG0584	glycerophosphoryl diester phosphodiesterase
DVJ83_08595	COG0587	DNA-directed DNA polymerase activity
DVJ83_08600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DVJ83_08620	COG0656	L-ascorbic acid biosynthetic process
DVJ83_08660	COG3685	Protein conserved in bacteria
DVJ83_08685	COG3654	unkown
DVJ83_08700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DVJ83_08705	COG0697	spore germination
DVJ83_08715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DVJ83_08795	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DVJ83_08800	COG0861	Integral membrane protein TerC family
DVJ83_08805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DVJ83_08865	COG0704	Plays a role in the regulation of phosphate uptake
DVJ83_08885	COG2205	protein histidine kinase activity
DVJ83_08915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DVJ83_08920	COG1233	COG1233 Phytoene dehydrogenase and related
DVJ83_08945	COG2311	Membrane
DVJ83_08980	COG1476	TRANSCRIPTIONal
DVJ83_08985	COG0552	protein localization to endoplasmic reticulum
DVJ83_09000	COG0783	Belongs to the Dps family
DVJ83_09005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVJ83_09010	COG0436	Aminotransferase
DVJ83_09015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DVJ83_09020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DVJ83_09035	COG5433	transposase activity
DVJ83_09040	COG5433	transposase activity
DVJ83_09075	COG1121	(ABC) transporter
DVJ83_09080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DVJ83_09085	COG0792	nuclease activity
DVJ83_09090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVJ83_09095	COG0571	ribonuclease III activity
DVJ83_09110	COG0556	nucleotide-excision repair
DVJ83_09135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DVJ83_09140	COG0194	GDP metabolic process
DVJ83_09145	COG0101	tRNA pseudouridine synthase activity
DVJ83_09185	COG1324	tolerance protein
DVJ83_09195	COG1940	carbohydrate kinase activity
DVJ83_09220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DVJ83_09260	COG2814	Major facilitator Superfamily
DVJ83_09265	COG1160	GTP binding
DVJ83_09280	COG2313	pseudouridylate synthase activity
DVJ83_09285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVJ83_09310	COG1131	(ABC) transporter
DVJ83_09315	COG0667	Aldo Keto reductase
DVJ83_09340	COG2050	protein possibly involved in aromatic compounds catabolism
DVJ83_09350	COG1253	flavin adenine dinucleotide binding
DVJ83_09355	COG1253	flavin adenine dinucleotide binding
DVJ83_09370	COG0745	RESPONSE REGULATOR receiver
DVJ83_09375	COG0642	Histidine kinase
DVJ83_09390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DVJ83_09405	COG1902	pentaerythritol trinitrate reductase activity
DVJ83_09405	COG0446	pyridine nucleotide-disulphide oxidoreductase
DVJ83_09415	COG1546	Belongs to the CinA family
DVJ83_09415	COG1058	Belongs to the CinA family
DVJ83_09420	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DVJ83_09425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DVJ83_09450	COG2095	MarC family integral membrane protein
DVJ83_09460	COG1408	metallophosphoesterase
DVJ83_09465	COG0156	8-amino-7-oxononanoate synthase activity
DVJ83_09490	COG0802	atpase or kinase
DVJ83_09495	COG0181	hydroxymethylbilane synthase activity
DVJ83_09500	COG0252	asparaginase activity
DVJ83_09505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DVJ83_09520	COG0072	phenylalanine-tRNA ligase activity
DVJ83_09520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DVJ83_09550	COG1960	acyl-CoA dehydrogenase activity
DVJ83_09570	COG0039	L-malate dehydrogenase activity
DVJ83_09575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DVJ83_09585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DVJ83_09595	COG2860	membrane
DVJ83_09605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DVJ83_09615	COG0193	aminoacyl-tRNA hydrolase activity
DVJ83_09640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DVJ83_09680	COG1012	belongs to the aldehyde dehydrogenase family
DVJ83_09680	COG2030	dehydratase
DVJ83_09695	COG2151	metal-sulfur cluster biosynthetic enzyme
DVJ83_09700	COG3396	Phenylacetate-CoA oxygenase
DVJ83_09710	COG3396	Phenylacetate-CoA oxygenase
DVJ83_09715	COG1854	S-ribosylhomocysteine lyase activity
DVJ83_09720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DVJ83_09730	COG0083	homoserine kinase activity
DVJ83_09775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DVJ83_09800	COG2315	Protein conserved in bacteria
DVJ83_09830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DVJ83_09860	COG2226	methyltransferase
DVJ83_09870	COG2050	protein possibly involved in aromatic compounds catabolism
DVJ83_09880	COG0523	cobalamin synthesis protein
DVJ83_09910	COG0745	RESPONSE REGULATOR receiver
DVJ83_09915	COG0642	Histidine kinase
DVJ83_09930	COG4251	negative regulation of phosphorylation
DVJ83_09935	COG0784	Response regulator, receiver
DVJ83_09950	COG1970	mechanosensitive ion channel activity
DVJ83_09955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DVJ83_09960	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DVJ83_09970	COG1056	cytidyltransferase-related domain
DVJ83_09970	COG1051	belongs to the nudix hydrolase family
DVJ83_09990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DVJ83_09990	COG3153	acetyltransferase
DVJ83_10005	COG0242	peptide deformylase activity
DVJ83_10010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DVJ83_10020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DVJ83_10030	COG2318	DinB family
DVJ83_10035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DVJ83_10045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DVJ83_10080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DVJ83_10090	COG1937	Protein conserved in bacteria
DVJ83_10100	COG2217	Heavy metal translocating P-type atpase
DVJ83_10130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DVJ83_10135	COG1418	mRNA catabolic process
DVJ83_10135	COG2433	Pfam Transposase IS66
DVJ83_10145	COG1047	Peptidyl-prolyl cis-trans
DVJ83_10175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DVJ83_10200	COG1024	Enoyl-CoA hydratase
DVJ83_10200	COG1250	3-hydroxyacyl-CoA dehydrogenase
DVJ83_10215	COG0183	Belongs to the thiolase family
DVJ83_10295	COG1758	RNA polymerase activity
DVJ83_10300	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DVJ83_10305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DVJ83_10315	COG0745	RESPONSE REGULATOR receiver
DVJ83_10315	COG3706	GGDEF domain
DVJ83_10320	COG0105	UTP biosynthetic process
DVJ83_10330	COG1609	Transcriptional regulator
DVJ83_10340	COG1505	serine-type exopeptidase activity
DVJ83_10355	COG2819	hydrolase of the alpha beta superfamily
DVJ83_10360	COG0318	PFAM AMP-dependent synthetase and ligase
DVJ83_10370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DVJ83_10375	COG1024	Enoyl-CoA hydratase
DVJ83_10380	COG1774	PSP1 C-terminal conserved region
DVJ83_10385	COG0251	oxidation-reduction process
DVJ83_10390	COG0631	protein serine/threonine phosphatase activity
DVJ83_10400	COG0612	Peptidase, M16
DVJ83_10415	COG0515	serine threonine protein kinase
DVJ83_10415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DVJ83_10425	COG0803	Belongs to the bacterial solute-binding protein 9 family
DVJ83_10430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DVJ83_10435	COG0523	cobalamin synthesis protein
DVJ83_10445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DVJ83_10500	COG3706	GGDEF domain
DVJ83_10505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DVJ83_10510	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DVJ83_10525	COG1228	amidohydrolase
DVJ83_10540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DVJ83_10550	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DVJ83_10565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DVJ83_10570	COG0217	transcriptional regulatory protein
DVJ83_10575	COG0596	Alpha beta hydrolase
DVJ83_10580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DVJ83_10585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVJ83_10595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DVJ83_10600	COG0745	RESPONSE REGULATOR receiver
DVJ83_10605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVJ83_10620	COG4895	conserved protein (DUF2196)
DVJ83_10640	COG2181	nitrate reductase activity
DVJ83_10640	COG0247	lactate metabolic process
DVJ83_10650	COG0018	arginyl-trna synthetase
DVJ83_10665	COG0315	cyclic pyranopterin monophosphate synthase activity
DVJ83_10680	COG1396	sequence-specific DNA binding
DVJ83_10685	COG0285	dihydrofolate synthase activity
DVJ83_10690	COG1227	inorganic diphosphatase activity
DVJ83_10695	COG3206	protein involved in exopolysaccharide biosynthesis
DVJ83_10700	COG0343	queuine tRNA-ribosyltransferase activity
DVJ83_10720	COG0799	negative regulation of ribosome biogenesis
DVJ83_10735	COG0281	malic enzyme
DVJ83_10745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DVJ83_10760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DVJ83_10765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVJ83_10770	COG1120	ATPase activity
DVJ83_10810	COG2321	neutral zinc metallopeptidase
DVJ83_10815	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DVJ83_10820	COG0432	Pfam Uncharacterised protein family UPF0047
DVJ83_10845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DVJ83_10850	COG0163	prenyltransferase activity
DVJ83_10855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DVJ83_10860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DVJ83_10870	COG4636	protein conserved in cyanobacteria
DVJ83_10910	COG0314	molybdopterin synthase activity
DVJ83_10925	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DVJ83_10930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DVJ83_10930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DVJ83_10935	COG0586	Pfam SNARE associated Golgi protein
DVJ83_10940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVJ83_10955	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DVJ83_10965	COG0109	protoheme IX farnesyltransferase activity
DVJ83_10965	COG1612	heme a metabolic process
DVJ83_10970	COG0109	protoheme IX farnesyltransferase activity
DVJ83_10985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DVJ83_10985	COG1845	cytochrome c oxidase, subunit III
DVJ83_10990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DVJ83_10995	COG2226	methyltransferase
DVJ83_11000	COG0492	ferredoxin-NADP+ reductase activity
DVJ83_11015	COG2272	Belongs to the type-B carboxylesterase lipase family
DVJ83_11025	COG0114	fumarate hydratase activity
DVJ83_11035	COG1695	Transcriptional regulator
DVJ83_11060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DVJ83_11065	COG0590	tRNA wobble adenosine to inosine editing
DVJ83_11070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DVJ83_11080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DVJ83_11095	COG0148	phosphopyruvate hydratase activity
DVJ83_11100	COG0592	DNA-directed DNA polymerase activity
DVJ83_11105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DVJ83_11115	COG1051	belongs to the nudix hydrolase family
DVJ83_11120	COG1378	Sugar-specific transcriptional regulator TrmB
DVJ83_11125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DVJ83_11130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DVJ83_11145	COG2720	vancomycin resistance protein
DVJ83_11150	COG1475	DNA binding
DVJ83_11155	COG1192	Involved in chromosome partitioning
DVJ83_11160	COG0357	Ribosomal RNA small subunit methyltransferase G
DVJ83_11170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DVJ83_11175	COG0557	exoribonuclease II activity
DVJ83_11205	COG2720	vancomycin resistance protein
DVJ83_11215	COG2226	methyltransferase
DVJ83_11220	COG0445	tRNA wobble uridine modification
DVJ83_11235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DVJ83_11240	COG0022	dehydrogenase e1 component
DVJ83_11270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DVJ83_11275	COG0302	gtp cyclohydrolase
DVJ83_11295	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DVJ83_11300	COG2199	diguanylate cyclase activity
DVJ83_11300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DVJ83_11340	COG4948	Mandelate Racemase Muconate Lactonizing
DVJ83_11375	COG2815	serine threonine protein kinase
DVJ83_11375	COG0515	serine threonine protein kinase
DVJ83_11385	COG2378	regulation of single-species biofilm formation
DVJ83_11395	COG2318	DinB family
DVJ83_11405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DVJ83_11415	COG3842	ATPase activity
DVJ83_11420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DVJ83_11425	COG1840	ABC-type Fe3 transport system, periplasmic component
DVJ83_11445	COG1205	dead DEAH box helicase
DVJ83_11445	COG1111	helicase
DVJ83_11455	COG2259	Doxx family
DVJ83_11490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DVJ83_11505	COG0280	phosphate acetyltransferase
DVJ83_11505	COG0857	belongs to the CobB CobQ family
DVJ83_11510	COG1309	transcriptional regulator
DVJ83_11515	COG1511	domain protein
DVJ83_11515	COG1511	domain protein
DVJ83_11525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DVJ83_11530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DVJ83_11535	COG0494	nUDIX hydrolase
DVJ83_11540	COG0494	nUDIX hydrolase
DVJ83_11545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DVJ83_11585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DVJ83_11590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DVJ83_11595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DVJ83_11600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DVJ83_11610	COG0463	Glycosyl transferase, family 2
DVJ83_11640	COG1132	(ABC) transporter
DVJ83_11645	COG0360	Binds together with S18 to 16S ribosomal RNA
DVJ83_11650	COG0629	single-stranded DNA binding
DVJ83_11655	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DVJ83_11660	COG0359	binds to the 23S rRNA
DVJ83_11675	COG0534	Mate efflux family protein
DVJ83_11680	COG2409	Drug exporters of the RND superfamily
DVJ83_11685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DVJ83_11690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DVJ83_11700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DVJ83_11705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DVJ83_11740	COG2967	ApaG domain
DVJ83_11755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DVJ83_11760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DVJ83_11765	COG0047	phosphoribosylformylglycinamidine synthase activity
DVJ83_11785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DVJ83_11790	COG2852	Protein conserved in bacteria
DVJ83_11795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DVJ83_11810	COG2897	thiosulfate sulfurtransferase activity
DVJ83_11825	COG1104	cysteine desulfurase activity
DVJ83_11840	COG0668	transmembrane transport
DVJ83_11850	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DVJ83_11865	COG1131	(ABC) transporter
DVJ83_11885	COG1522	sequence-specific DNA binding
DVJ83_11890	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DVJ83_11895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DVJ83_11905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DVJ83_11915	COG2738	Putative neutral zinc metallopeptidase
DVJ83_11940	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_11965	COG0439	Biotin carboxylase
DVJ83_11970	COG0511	ligase activity, forming carbon-carbon bonds
DVJ83_11975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DVJ83_11980	COG0758	DNA mediated transformation
DVJ83_11990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DVJ83_11995	COG0135	phosphoribosylanthranilate isomerase activity
DVJ83_12020	COG0484	heat shock protein binding
DVJ83_12025	COG4628	conserved protein (DUF2132)
DVJ83_12030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DVJ83_12035	COG0443	Heat shock 70 kDa protein
DVJ83_12040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DVJ83_12050	COG2326	polyphosphate kinase activity
DVJ83_12055	COG0697	spore germination
DVJ83_12075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DVJ83_12080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DVJ83_12100	COG0084	hydrolase, TatD family'
DVJ83_12135	COG0525	valine-tRNA ligase activity
DVJ83_12140	COG1051	belongs to the nudix hydrolase family
DVJ83_12150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DVJ83_12150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DVJ83_12160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DVJ83_12160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DVJ83_12165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DVJ83_12175	COG0572	uridine kinase
DVJ83_12195	COG1506	peptidase
DVJ83_12195	COG4946	Tricorn protease homolog
DVJ83_12195	COG0823	Involved in the tonB-independent uptake of proteins
DVJ83_12210	COG2856	Zn peptidase
DVJ83_12215	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DVJ83_12235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DVJ83_12240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DVJ83_12250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DVJ83_12275	COG0067	glutamate synthase
DVJ83_12275	COG0069	glutamate synthase activity
DVJ83_12275	COG0070	glutamate synthase
DVJ83_12285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DVJ83_12290	COG1570	exodeoxyribonuclease VII activity
DVJ83_12295	COG2949	membrane
DVJ83_12305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DVJ83_12310	COG2309	aminopeptidase activity
DVJ83_12315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DVJ83_12320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DVJ83_12355	COG1166	arginine decarboxylase activity
DVJ83_12360	COG2890	protein-(glutamine-N5) methyltransferase activity
DVJ83_12370	COG0736	holo-[acyl-carrier-protein] synthase activity
DVJ83_12400	COG0628	permease
DVJ83_12430	COG0508	dehydrogenase complex catalyzes the overall conversion of
DVJ83_12440	COG4143	(ABC) transporter
DVJ83_12465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DVJ83_12490	COG0513	Belongs to the DEAD box helicase family
DVJ83_12520	COG3386	PFAM SMP-30 Gluconolaconase
DVJ83_12525	COG0406	alpha-ribazole phosphatase activity
DVJ83_12530	COG1607	acyl-coa hydrolase
DVJ83_12545	COG4177	L-phenylalanine transmembrane transporter activity
DVJ83_12550	COG0411	ABC transporter
DVJ83_12555	COG0410	ABC transporter
DVJ83_12575	COG0567	Dehydrogenase, E1 component
DVJ83_12600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DVJ83_12630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DVJ83_12635	COG1428	Deoxynucleoside kinase
DVJ83_12640	COG1428	Deoxynucleoside kinase
DVJ83_12645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVJ83_12655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DVJ83_12670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DVJ83_12675	COG0049	tRNA binding
DVJ83_12680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DVJ83_12690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DVJ83_12695	COG0051	transcription antitermination factor activity, RNA binding
DVJ83_12700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DVJ83_12705	COG0088	Forms part of the polypeptide exit tunnel
DVJ83_12710	COG0089	rRNA binding
DVJ83_12715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DVJ83_12720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DVJ83_12725	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DVJ83_12730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DVJ83_12735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DVJ83_12740	COG0255	Belongs to the universal ribosomal protein uL29 family
DVJ83_12745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DVJ83_12750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DVJ83_12755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DVJ83_12760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DVJ83_12775	COG3404	Formiminotransferase-cyclodeaminase
DVJ83_12780	COG0039	L-malate dehydrogenase activity
DVJ83_12810	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DVJ83_12820	COG0513	Belongs to the DEAD box helicase family
DVJ83_12845	COG0285	dihydrofolate synthase activity
DVJ83_12855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DVJ83_12860	COG0723	plastoquinol--plastocyanin reductase activity
DVJ83_12875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DVJ83_12880	COG1138	Cytochrome C-type biogenesis protein
DVJ83_12885	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DVJ83_12895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DVJ83_12900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DVJ83_12920	COG0708	Exodeoxyribonuclease III
DVJ83_12945	COG1678	Uncharacterized ACR, COG1678
DVJ83_12950	COG0354	folic acid binding
DVJ83_12970	COG1181	Belongs to the D-alanine--D-alanine ligase family
DVJ83_12975	COG0747	negative chemotaxis
DVJ83_12980	COG0601	transmembrane transport
DVJ83_12985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVJ83_12995	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DVJ83_13010	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DVJ83_13020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DVJ83_13035	COG1760	l-serine dehydratase
DVJ83_13065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DVJ83_13090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DVJ83_13110	COG1461	Dihydroxyacetone kinase
DVJ83_13135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DVJ83_13145	COG0243	molybdopterin cofactor binding
DVJ83_13150	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DVJ83_13165	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
DVJ83_13200	COG0784	Response regulator, receiver
DVJ83_13220	COG4221	oxidoreductase activity
DVJ83_13260	COG4106	trans-aconitate 2-methyltransferase activity
DVJ83_13270	COG4712	double-strand break repair protein
DVJ83_13275	COG0131	Imidazoleglycerol-phosphate dehydratase
DVJ83_13285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DVJ83_13290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DVJ83_13295	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DVJ83_13295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DVJ83_13315	COG2197	response regulator
DVJ83_13340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DVJ83_13355	COG0316	Belongs to the HesB IscA family
DVJ83_13360	COG4166	transmembrane transport
DVJ83_13365	COG0601	transmembrane transport
DVJ83_13370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVJ83_13375	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DVJ83_13385	COG0477	Major facilitator Superfamily
DVJ83_13390	COG0747	negative chemotaxis
DVJ83_13400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DVJ83_13400	COG1017	nitric oxide dioxygenase activity
DVJ83_13405	COG1959	2 iron, 2 sulfur cluster binding
DVJ83_13415	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DVJ83_13420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DVJ83_13440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DVJ83_13445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DVJ83_13450	COG2080	2 iron, 2 sulfur cluster binding
DVJ83_13455	COG2080	2 iron, 2 sulfur cluster binding
DVJ83_13460	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DVJ83_13465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DVJ83_13505	COG2368	4-hydroxyphenylacetate
DVJ83_13515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DVJ83_13530	COG3835	regulator
DVJ83_13540	COG1174	glycine betaine transport
DVJ83_13545	COG0517	IMP dehydrogenase activity
DVJ83_13545	COG1125	glycine betaine transport
DVJ83_13585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DVJ83_13590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DVJ83_13595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DVJ83_13600	COG2188	Transcriptional regulator
DVJ83_13605	COG0747	negative chemotaxis
DVJ83_13610	COG0601	transmembrane transport
DVJ83_13615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVJ83_13675	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_13680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DVJ83_13685	COG2032	superoxide dismutase activity
DVJ83_13695	COG0784	Response regulator, receiver
DVJ83_13700	COG4251	negative regulation of phosphorylation
DVJ83_13725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DVJ83_13745	COG0248	Ppx GppA phosphatase
DVJ83_13750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DVJ83_13760	COG2252	PERMEase
DVJ83_13780	COG1268	BioY protein
DVJ83_13785	COG1122	ATPase activity
DVJ83_13790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DVJ83_13795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DVJ83_13800	COG0352	thiamine-phosphate diphosphorylase activity
DVJ83_13805	COG2022	thiamine diphosphate biosynthetic process
DVJ83_13855	COG0725	ABC transporter, periplasmic molybdate-binding protein
DVJ83_13865	COG3118	belongs to the thioredoxin family
DVJ83_13880	COG0730	response to heat
DVJ83_13885	COG0704	Plays a role in the regulation of phosphate uptake
DVJ83_13890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DVJ83_13895	COG0581	inorganic phosphate transmembrane transporter activity
DVJ83_13905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DVJ83_13910	COG1937	Protein conserved in bacteria
DVJ83_13915	COG4974	Belongs to the 'phage' integrase family
DVJ83_13920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DVJ83_13940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DVJ83_13945	COG4636	protein conserved in cyanobacteria
DVJ83_13950	COG0010	Belongs to the arginase family
DVJ83_13955	COG1228	amidohydrolase
DVJ83_13960	COG2986	histidine ammonia-lyase
DVJ83_13985	COG3971	2-oxopent-4-enoate hydratase activity
DVJ83_13990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DVJ83_13995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVJ83_14005	COG0402	S-adenosylhomocysteine deaminase activity
DVJ83_14020	COG1414	Transcriptional regulator
DVJ83_14045	COG2217	Heavy metal translocating P-type atpase
DVJ83_14050	COG0640	Transcriptional regulator
DVJ83_14055	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DVJ83_14090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DVJ83_14095	COG0776	regulation of translation
DVJ83_14115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVJ83_14120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DVJ83_14125	COG0183	Belongs to the thiolase family
DVJ83_14130	COG1482	cell wall glycoprotein biosynthetic process
DVJ83_14135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DVJ83_14155	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DVJ83_14170	COG0438	transferase activity, transferring glycosyl groups
DVJ83_14185	COG0438	transferase activity, transferring glycosyl groups
DVJ83_14215	COG1012	belongs to the aldehyde dehydrogenase family
DVJ83_14230	COG1509	lysine 2,3-aminomutase activity
DVJ83_14235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DVJ83_14250	COG3483	tryptophan 2,3-dioxygenase activity
DVJ83_14255	COG3844	kynureninase activity
DVJ83_14260	COG1960	acyl-CoA dehydrogenase activity
DVJ83_14265	COG2815	serine threonine protein kinase
DVJ83_14265	COG0515	serine threonine protein kinase
DVJ83_14280	COG0515	serine threonine protein kinase
DVJ83_14290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DVJ83_14300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVJ83_14305	COG1012	belongs to the aldehyde dehydrogenase family
DVJ83_14325	COG0840	transmembrane signaling receptor activity
DVJ83_14335	COG0840	transmembrane signaling receptor activity
DVJ83_14390	COG0584	glycerophosphoryl diester phosphodiesterase
DVJ83_14400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DVJ83_14405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DVJ83_14415	COG1607	acyl-coa hydrolase
DVJ83_14450	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DVJ83_14465	COG2375	cellular response to nickel ion
DVJ83_14475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVJ83_14480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DVJ83_14490	COG1192	Involved in chromosome partitioning
DVJ83_14495	COG1475	DNA binding
DVJ83_14500	COG1012	belongs to the aldehyde dehydrogenase family
DVJ83_14520	COG0737	Belongs to the 5'-nucleotidase family
DVJ83_14535	COG1464	Belongs to the NlpA lipoprotein family
DVJ83_14545	COG2011	ABC-type metal ion transport system permease component
DVJ83_14550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DVJ83_14585	COG1404	Belongs to the peptidase S8 family
DVJ83_14590	COG4932	domain protein
DVJ83_14600	COG1136	(ABC) transporter
DVJ83_14610	COG0577	efflux transmembrane transporter activity
DVJ83_14615	COG0861	Integral membrane protein TerC family
DVJ83_14620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DVJ83_14625	COG0281	malic enzyme
DVJ83_14645	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DVJ83_14655	COG0477	Major facilitator Superfamily
DVJ83_14680	COG0318	PFAM AMP-dependent synthetase and ligase
DVJ83_14695	COG0411	ABC transporter
DVJ83_14715	COG0753	catalase activity
DVJ83_14715	COG0693	protein deglycase activity
DVJ83_14730	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DVJ83_14735	COG2366	antibiotic biosynthetic process
DVJ83_14740	COG0789	Transcriptional regulator
DVJ83_14745	COG1063	alcohol dehydrogenase
DVJ83_14750	COG1960	acyl-CoA dehydrogenase activity
DVJ83_14760	COG1192	Involved in chromosome partitioning
DVJ83_14790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVJ83_14795	COG0589	response to stress
DVJ83_14810	COG0542	response to heat
DVJ83_14820	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
DVJ83_14840	COG0582	viral genome integration into host DNA
DVJ83_14935	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DVJ83_15025	COG2205	protein histidine kinase activity
DVJ83_15030	COG0745	RESPONSE REGULATOR receiver
DVJ83_15035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DVJ83_15110	COG3177	Filamentation induced by cAMP protein fic
DVJ83_15145	COG1192	Involved in chromosome partitioning
DVJ83_15150	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DVJ83_15200	COG0640	Transcriptional regulator
DVJ83_15215	COG2217	Heavy metal translocating P-type atpase
DVJ83_15220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DVJ83_15250	COG3311	Transcriptional regulator
DVJ83_15260	COG1002	Type II restriction enzyme, methylase subunits
DVJ83_15330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DVJ83_15355	COG2337	Toxic component of a toxin-antitoxin (TA) module
DVJ83_15465	COG1404	Belongs to the peptidase S8 family
DVJ83_15580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DVJ83_15585	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DVJ83_15590	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DVJ83_15595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DVJ83_15655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DVJ83_15670	COG0464	growth
DVJ83_15685	COG0556	nucleotide-excision repair
DVJ83_15705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DVJ83_15755	COG0675	Transposase, IS605 OrfB family
DVJ83_15815	COG1475	DNA binding
DVJ83_15840	COG1136	(ABC) transporter
DVJ83_15850	COG1785	Belongs to the alkaline phosphatase family
DVJ83_16090	COG0629	single-stranded DNA binding
DVJ83_16235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DVJ83_16270	COG1132	(ABC) transporter
DVJ83_16315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DVJ83_16345	COG4770	biotin carboxylase activity
DVJ83_16350	COG0318	PFAM AMP-dependent synthetase and ligase
DVJ83_16370	COG0776	regulation of translation
DVJ83_16455	COG0259	pyridoxamine-phosphate oxidase activity
DVJ83_16460	COG4644	lycopene metabolic process
DVJ83_16485	COG0415	Belongs to the DNA photolyase family
DVJ83_16525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVJ83_16530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DVJ83_16535	COG0395	ABC-type sugar transport system, permease component
DVJ83_16545	COG1653	transport
DVJ83_16550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DVJ83_16555	COG0165	Argininosuccinate lyase
DVJ83_16565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVJ83_16580	COG3290	protein histidine kinase activity
DVJ83_16605	COG1111	helicase
DVJ83_16605	COG1205	dead DEAH box helicase
DVJ83_16610	COG0514	ATP-dependent DNA helicase (RecQ)
DVJ83_16620	COG0758	DNA mediated transformation
DVJ83_16715	COG0675	Transposase, IS605 OrfB family
DVJ83_16815	COG1914	H( )-stimulated, divalent metal cation uptake system
DVJ83_16820	COG1321	iron dependent repressor
DVJ83_16840	COG2234	aminopeptidase activity
DVJ83_16935	COG4942	peptidase
DVJ83_17010	COG0437	4 iron, 4 sulfur cluster binding
DVJ83_17015	COG0243	molybdopterin cofactor binding
DVJ83_17065	COG1388	LysM domain
DVJ83_17065	COG3942	CHAP domain
DVJ83_17070	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DVJ83_17090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DVJ83_17105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DVJ83_17115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DVJ83_17120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DVJ83_17130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DVJ83_17200	COG0210	DNA helicase
DVJ83_17255	COG4644	lycopene metabolic process
DVJ83_17260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DVJ83_17265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DVJ83_17275	COG3335	DDE superfamily endonuclease
DVJ83_17290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DVJ83_17335	COG0784	Response regulator, receiver
DVJ83_17345	COG0776	regulation of translation
DVJ83_17360	COG0583	DNA-binding transcription factor activity
DVJ83_17495	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DVJ83_17515	COG0582	viral genome integration into host DNA
DVJ83_17585	COG1131	(ABC) transporter
DVJ83_17590	COG1725	Transcriptional regulator
DVJ83_17680	COG1475	DNA binding
DVJ83_17685	COG1192	Involved in chromosome partitioning
DVJ83_17750	COG3335	DDE superfamily endonuclease
DVJ83_17765	COG0640	Transcriptional regulator
DVJ83_17790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DVJ83_17800	COG2217	Heavy metal translocating P-type atpase
DVJ83_17820	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DVJ83_17825	COG1388	LysM domain
DVJ83_17825	COG3942	CHAP domain
DVJ83_17830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DVJ83_17830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DVJ83_17835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DVJ83_18090	COG2389	metal-binding protein
DVJ83_18115	COG1028	Short-chain dehydrogenase reductase Sdr
DVJ83_18145	COG3706	GGDEF domain
DVJ83_18160	COG1569	PIN domain
DVJ83_18170	COG0582	viral genome integration into host DNA
DVJ83_18190	COG2165	general secretion pathway protein
DVJ83_18195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DVJ83_18205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DVJ83_18245	COG0243	molybdopterin cofactor binding
DVJ83_18250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DVJ83_18250	COG2146	nitrite reductase [NAD(P)H] activity
DVJ83_18285	COG2046	Belongs to the sulfate adenylyltransferase family
DVJ83_18290	COG0175	sulfate reduction
DVJ83_18295	COG0529	Catalyzes the synthesis of activated sulfate
DVJ83_18300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DVJ83_18315	COG1012	belongs to the aldehyde dehydrogenase family
DVJ83_18320	COG1914	H( )-stimulated, divalent metal cation uptake system
DVJ83_18335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DVJ83_18340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DVJ83_18360	COG0477	Major facilitator Superfamily
DVJ83_18380	COG0346	lactoylglutathione lyase activity
DVJ83_18395	COG0655	NAD(P)H dehydrogenase (quinone) activity
DVJ83_18415	COG2132	Multicopper oxidase
DVJ83_18430	COG2217	Heavy metal translocating P-type atpase
DVJ83_18435	COG1937	Protein conserved in bacteria
DVJ83_18460	COG2132	Multicopper oxidase
DVJ83_18480	COG5002	protein histidine kinase activity
DVJ83_18515	COG1131	(ABC) transporter
DVJ83_18530	COG4585	Histidine kinase
DVJ83_18535	COG2197	response regulator
DVJ83_18555	COG1569	PIN domain
DVJ83_18565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DVJ83_18660	COG1492	cobalamin metabolic process
DVJ83_18690	COG2205	protein histidine kinase activity
DVJ83_18695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DVJ83_18700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVJ83_18700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DVJ83_18705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DVJ83_18710	COG1349	DNA-binding transcription factor activity
DVJ83_18775	COG2161	toxin-antitoxin pair type II binding
DVJ83_18790	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DVJ83_18925	COG1192	Involved in chromosome partitioning