locus-tag	class	description
Krodi_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Krodi_0004	COG0070	glutamate synthase
Krodi_0004	COG0067	glutamate synthase
Krodi_0004	COG0069	glutamate synthase activity
Krodi_0006	COG0347	Belongs to the P(II) protein family
Krodi_0007	COG0004	ammonium transporteR
Krodi_0008	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Krodi_0010	COG3530	Putative quorum-sensing-regulated virulence factor
Krodi_0012	COG1228	amidohydrolase
Krodi_0020	COG0019	diaminopimelate decarboxylase activity
Krodi_0022	COG2824	Alkylphosphonate utilization operon protein PhnA
Krodi_0025	COG0482	sulfurtransferase activity
Krodi_0027	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Krodi_0035	COG0791	NLP P60 protein
Krodi_0035	COG1388	LysM domain
Krodi_0036	COG0519	Catalyzes the synthesis of GMP from XMP
Krodi_0036	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Krodi_0038	COG1522	sequence-specific DNA binding
Krodi_0045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Krodi_0046	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Krodi_0047	COG0254	rRNA binding
Krodi_0049	COG0463	Glycosyl transferase, family 2
Krodi_0050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Krodi_0051	COG1132	(ABC) transporter
Krodi_0056	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Krodi_0059	COG1607	acyl-coa hydrolase
Krodi_0065	COG1301	dicarboxylic acid transport
Krodi_0066	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Krodi_0068	COG0277	FAD linked oxidase domain protein
Krodi_0068	COG0247	lactate metabolic process
Krodi_0070	COG0438	transferase activity, transferring glycosyl groups
Krodi_0071	COG1472	Belongs to the glycosyl hydrolase 3 family
Krodi_0073	COG0247	lactate metabolic process
Krodi_0073	COG2181	nitrate reductase activity
Krodi_0076	COG0247	lactate metabolic process
Krodi_0076	COG2181	nitrate reductase activity
Krodi_0078	COG0860	N-Acetylmuramoyl-L-alanine amidase
Krodi_0080	COG0251	oxidation-reduction process
Krodi_0086	COG0009	L-threonylcarbamoyladenylate synthase
Krodi_0092	COG3586	endonuclease activity
Krodi_0102	COG2226	methyltransferase
Krodi_0105	COG3878	Protein conserved in bacteria
Krodi_0108	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Krodi_0110	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Krodi_0111	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Krodi_0111	COG2885	chlorophyll binding
Krodi_0114	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Krodi_0117	COG0686	Belongs to the AlaDH PNT family
Krodi_0132	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Krodi_0132	COG1703	isobutyryl-CoA mutase activity
Krodi_0132	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Krodi_0133	COG0788	formyltetrahydrofolate deformylase activity
Krodi_0136	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Krodi_0137	COG0284	orotidine-5'-phosphate decarboxylase activity
Krodi_0138	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Krodi_0141	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Krodi_0144	COG1462	curli production assembly transport component CsgG
Krodi_0150	COG0174	glutamine synthetase
Krodi_0152	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Krodi_0154	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Krodi_0165	COG0443	Heat shock 70 kDa protein
Krodi_0168	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Krodi_0169	COG2318	DinB family
Krodi_0170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Krodi_0172	COG0101	tRNA pseudouridine synthase activity
Krodi_0173	COG1132	(ABC) transporter
Krodi_0177	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Krodi_0179	COG0326	Molecular chaperone. Has ATPase activity
Krodi_0182	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Krodi_0184	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Krodi_0185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Krodi_0189	COG0456	acetyltransferase
Krodi_0190	COG0336	Belongs to the RNA methyltransferase TrmD family
Krodi_0192	COG2814	Major facilitator Superfamily
Krodi_0198	COG1522	sequence-specific DNA binding
Krodi_0199	COG0626	cystathionine gamma-synthase activity
Krodi_0201	COG0450	alkyl hydroperoxide reductase
Krodi_0202	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Krodi_0205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Krodi_0210	COG1674	ftsk spoiiie
Krodi_0213	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Krodi_0213	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Krodi_0220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Krodi_0225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Krodi_0232	COG0488	(ABC) transporter
Krodi_0236	COG4628	conserved protein (DUF2132)
Krodi_0239	COG3956	TIGRFAM MazG family protein
Krodi_0241	COG0242	peptide deformylase activity
Krodi_0242	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Krodi_0243	COG2171	N-acyltransferase activity
Krodi_0247	COG0539	negative regulation of cytoplasmic translation
Krodi_0255	COG2154	pterin-4-alpha-carbinolamine dehydratase
Krodi_0256	COG0217	transcriptional regulatory protein
Krodi_0259	COG0010	Belongs to the arginase family
Krodi_0263	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Krodi_0265	COG4948	Mandelate Racemase Muconate Lactonizing
Krodi_0267	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Krodi_0269	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Krodi_0276	COG1970	mechanosensitive ion channel activity
Krodi_0277	COG2270	Major facilitator Superfamily
Krodi_0278	COG4783	chaperone-mediated protein folding
Krodi_0281	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Krodi_0282	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Krodi_0283	COG0297	glycogen (starch) synthase activity
Krodi_0284	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Krodi_0285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Krodi_0286	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Krodi_0288	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Krodi_0290	COG4974	Belongs to the 'phage' integrase family
Krodi_0297	COG1678	Uncharacterized ACR, COG1678
Krodi_0298	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Krodi_0300	COG0671	phosphoesterase, PA-phosphatase related
Krodi_0303	COG2095	MarC family integral membrane protein
Krodi_0304	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Krodi_0305	COG0800	Aldolase
Krodi_0307	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_0308	COG2271	Major facilitator Superfamily
Krodi_0309	COG2186	Transcriptional regulator
Krodi_0313	COG1629	transport
Krodi_0313	COG4206	TonB-dependent receptor
Krodi_0322	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Krodi_0331	COG1215	transferase activity, transferring glycosyl groups
Krodi_0332	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Krodi_0333	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Krodi_0334	COG0440	acetolactate synthase activity
Krodi_0335	COG0028	Belongs to the TPP enzyme family
Krodi_0336	COG0129	dihydroxy-acid dehydratase activity
Krodi_0337	COG1012	belongs to the aldehyde dehydrogenase family
Krodi_0339	COG1984	allophanate hydrolase subunit 2
Krodi_0340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Krodi_0342	COG1914	H( )-stimulated, divalent metal cation uptake system
Krodi_0343	COG5002	protein histidine kinase activity
Krodi_0343	COG0784	Response regulator, receiver
Krodi_0343	COG2198	Histidine kinase
Krodi_0344	COG0606	chelatase, subunit chli
Krodi_0347	COG0037	tRNA processing
Krodi_0349	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Krodi_0350	COG1115	amino acid carrier protein
Krodi_0352	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Krodi_0353	COG1702	phosphate starvation-inducible protein PhoH
Krodi_0360	COG0784	Response regulator, receiver
Krodi_0361	COG4251	negative regulation of phosphorylation
Krodi_0363	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Krodi_0364	COG0085	RNA polymerase activity
Krodi_0365	COG0222	ribosome binding
Krodi_0366	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Krodi_0367	COG0081	regulation of translation
Krodi_0368	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Krodi_0371	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Krodi_0372	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Krodi_0373	COG4974	Belongs to the 'phage' integrase family
Krodi_0374	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Krodi_0375	COG1960	acyl-CoA dehydrogenase activity
Krodi_0377	COG1115	amino acid carrier protein
Krodi_0378	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Krodi_0380	COG0514	ATP-dependent DNA helicase (RecQ)
Krodi_0381	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Krodi_0381	COG0517	IMP dehydrogenase activity
Krodi_0382	COG0805	protein transport
Krodi_0385	COG1137	ATPase activity
Krodi_0389	COG3279	Response regulator of the LytR AlgR family
Krodi_0390	COG0302	gtp cyclohydrolase
Krodi_0391	COG0215	cysteine-tRNA ligase activity
Krodi_0392	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Krodi_0393	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Krodi_0396	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Krodi_0397	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Krodi_0398	COG1058	Belongs to the CinA family
Krodi_0398	COG1546	Belongs to the CinA family
Krodi_0400	COG0179	Fumarylacetoacetate (FAA) hydrolase
Krodi_0401	COG5002	protein histidine kinase activity
Krodi_0401	COG2176	DNA-directed DNA polymerase activity
Krodi_0406	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Krodi_0407	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Krodi_0408	COG0673	inositol 2-dehydrogenase activity
Krodi_0409	COG1250	3-hydroxyacyl-CoA dehydrogenase
Krodi_0412	COG2176	DNA-directed DNA polymerase activity
Krodi_0413	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Krodi_0414	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Krodi_0417	COG0237	dephospho-CoA kinase activity
Krodi_0419	COG0463	Glycosyl transferase, family 2
Krodi_0420	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Krodi_0421	COG0497	DNA recombination
Krodi_0426	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Krodi_0428	COG0737	Belongs to the 5'-nucleotidase family
Krodi_0429	COG0737	Belongs to the 5'-nucleotidase family
Krodi_0432	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Krodi_0434	COG2890	protein-(glutamine-N5) methyltransferase activity
Krodi_0436	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Krodi_0436	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Krodi_0448	COG1396	sequence-specific DNA binding
Krodi_0450	COG1842	Phage shock protein A
Krodi_0453	COG2255	four-way junction helicase activity
Krodi_0456	COG2133	pyrroloquinoline quinone binding
Krodi_0458	COG1192	Involved in chromosome partitioning
Krodi_0459	COG1475	DNA binding
Krodi_0461	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Krodi_0467	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Krodi_0469	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Krodi_0471	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Krodi_0474	COG0018	arginyl-trna synthetase
Krodi_0478	COG0492	ferredoxin-NADP+ reductase activity
Krodi_0479	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Krodi_0480	COG0569	domain protein
Krodi_0481	COG2226	methyltransferase
Krodi_0483	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Krodi_0486	COG0191	fructose-bisphosphate aldolase activity
Krodi_0487	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Krodi_0489	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Krodi_0490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Krodi_0492	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Krodi_0494	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Krodi_0501	COG1490	D-aminoacyl-tRNA deacylase activity
Krodi_0502	COG1162	GTPase activity
Krodi_0504	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Krodi_0505	COG0287	Prephenate dehydrogenase
Krodi_0506	COG0436	Aminotransferase
Krodi_0507	COG0077	Prephenate dehydratase
Krodi_0507	COG1605	Chorismate mutase
Krodi_0511	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Krodi_0512	COG1185	polyribonucleotide nucleotidyltransferase activity
Krodi_0522	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Krodi_0527	COG0798	PFAM Bile acid sodium symporter
Krodi_0538	COG3340	Belongs to the peptidase S51 family
Krodi_0545	COG2153	protein acetylation
Krodi_0549	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Krodi_0550	COG0563	adenylate kinase activity
Krodi_0551	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Krodi_0552	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Krodi_0559	COG1090	epimerase
Krodi_0563	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Krodi_0563	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Krodi_0564	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Krodi_0566	COG1216	Glycosyl transferase, family 2
Krodi_0566	COG0463	Glycosyl transferase, family 2
Krodi_0567	COG1785	Belongs to the alkaline phosphatase family
Krodi_0568	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Krodi_0569	COG1127	ABC transporter
Krodi_0571	COG0662	Cupin 2, conserved barrel domain protein
Krodi_0571	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Krodi_0573	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_0576	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Krodi_0577	COG0295	cytidine deaminase activity
Krodi_0580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Krodi_0581	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Krodi_0582	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Krodi_0583	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Krodi_0584	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Krodi_0591	COG1131	(ABC) transporter
Krodi_0593	COG0285	dihydrofolate synthase activity
Krodi_0595	COG0848	biopolymer transport protein
Krodi_0596	COG0811	peptide transport
Krodi_0598	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Krodi_0599	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Krodi_0600	COG1960	acyl-CoA dehydrogenase activity
Krodi_0602	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Krodi_0604	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Krodi_0606	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Krodi_0607	COG0791	NLP P60 protein
Krodi_0608	COG2333	competence protein COMEC
Krodi_0608	COG0658	competence protein
Krodi_0610	COG3104	oligopeptide transport
Krodi_0611	COG0823	Involved in the tonB-independent uptake of proteins
Krodi_0611	COG1506	peptidase
Krodi_0614	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Krodi_0615	COG1253	flavin adenine dinucleotide binding
Krodi_0620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Krodi_0624	COG2017	converts alpha-aldose to the beta-anomer
Krodi_0628	COG1629	transport
Krodi_0628	COG4206	TonB-dependent receptor
Krodi_0637	COG2226	methyltransferase
Krodi_0645	COG0401	homolog of Blt101
Krodi_0646	COG2198	Histidine kinase
Krodi_0646	COG5002	protein histidine kinase activity
Krodi_0646	COG0784	Response regulator, receiver
Krodi_0652	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Krodi_0661	COG0439	Biotin carboxylase
Krodi_0662	COG0511	ligase activity, forming carbon-carbon bonds
Krodi_0663	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Krodi_0664	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Krodi_0666	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Krodi_0667	COG0307	riboflavin synthase, alpha
Krodi_0669	COG0346	lactoylglutathione lyase activity
Krodi_0670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Krodi_0671	COG4591	ABC-type transport system involved in lipoprotein release permease component
Krodi_0672	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Krodi_0674	COG0481	GTPase activity
Krodi_0676	COG3537	Alpha-1,2-mannosidase
Krodi_0677	COG2897	thiosulfate sulfurtransferase activity
Krodi_0678	COG1446	asparaginase
Krodi_0680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Krodi_0680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Krodi_0684	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Krodi_0685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Krodi_0686	COG0052	Belongs to the universal ribosomal protein uS2 family
Krodi_0687	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Krodi_0692	COG0528	UMP kinase activity
Krodi_0693	COG0233	cytoplasmic translational termination
Krodi_0696	COG0259	pyridoxamine-phosphate oxidase activity
Krodi_0697	COG0017	Asparaginyl-tRNA synthetase
Krodi_0704	COG4585	Histidine kinase
Krodi_0705	COG2197	response regulator
Krodi_0707	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Krodi_0709	COG2066	Belongs to the glutaminase family
Krodi_0718	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Krodi_0718	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Krodi_0720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Krodi_0721	COG0501	Belongs to the peptidase M48B family
Krodi_0722	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Krodi_0725	COG3152	Membrane
Krodi_0732	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Krodi_0733	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Krodi_0734	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Krodi_0735	COG1805	sodium ion transport
Krodi_0736	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Krodi_0742	COG1012	belongs to the aldehyde dehydrogenase family
Krodi_0744	COG0175	sulfate reduction
Krodi_0747	COG1959	2 iron, 2 sulfur cluster binding
Krodi_0748	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Krodi_0749	COG1410	methionine synthase
Krodi_0749	COG0646	methionine synthase
Krodi_0750	COG0646	methionine synthase
Krodi_0750	COG1410	methionine synthase
Krodi_0752	COG0527	aspartate kinase activity
Krodi_0752	COG0460	homoserine dehydrogenase
Krodi_0753	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Krodi_0755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Krodi_0765	COG1428	Deoxynucleoside kinase
Krodi_0769	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Krodi_0770	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Krodi_0772	COG0508	dehydrogenase complex catalyzes the overall conversion of
Krodi_0772	COG0022	dehydrogenase e1 component
Krodi_0773	COG2086	electron transfer activity
Krodi_0774	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Krodi_0776	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Krodi_0778	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Krodi_0781	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Krodi_0782	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Krodi_0787	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Krodi_0788	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Krodi_0795	COG1519	Transferase
Krodi_0798	COG2885	chlorophyll binding
Krodi_0802	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Krodi_0803	COG1629	transport
Krodi_0803	COG4206	TonB-dependent receptor
Krodi_0805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Krodi_0812	COG1428	Deoxynucleoside kinase
Krodi_0818	COG1160	GTP binding
Krodi_0823	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Krodi_0825	COG0544	peptidyl-prolyl cis-trans isomerase activity
Krodi_0826	COG1950	PFAM Membrane protein of
Krodi_0829	COG0596	Alpha beta hydrolase
Krodi_0830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Krodi_0832	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Krodi_0834	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Krodi_0835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Krodi_0838	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Krodi_0839	COG3279	Response regulator of the LytR AlgR family
Krodi_0840	COG3275	phosphorelay sensor kinase activity
Krodi_0844	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Krodi_0845	COG1960	acyl-CoA dehydrogenase activity
Krodi_0846	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Krodi_0847	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Krodi_0848	COG0228	four-way junction DNA binding
Krodi_0854	COG4585	Histidine kinase
Krodi_0856	COG0508	dehydrogenase complex catalyzes the overall conversion of
Krodi_0861	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Krodi_0861	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Krodi_0863	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Krodi_0865	COG0572	uridine kinase
Krodi_0867	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Krodi_0874	COG0166	Belongs to the GPI family
Krodi_0876	COG3483	tryptophan 2,3-dioxygenase activity
Krodi_0878	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Krodi_0881	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Krodi_0882	COG3938	Belongs to the proline racemase family
Krodi_0885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Krodi_0888	COG4251	negative regulation of phosphorylation
Krodi_0891	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Krodi_0892	COG2315	Protein conserved in bacteria
Krodi_0900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Krodi_0901	COG0784	Response regulator, receiver
Krodi_0901	COG2198	Histidine kinase
Krodi_0901	COG2205	protein histidine kinase activity
Krodi_0902	COG0629	single-stranded DNA binding
Krodi_0904	COG0439	Biotin carboxylase
Krodi_0905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Krodi_0906	COG0514	ATP-dependent DNA helicase (RecQ)
Krodi_0907	COG0471	metal ion transport
Krodi_0909	COG0500	methyltransferase
Krodi_0910	COG4251	negative regulation of phosphorylation
Krodi_0912	COG2201	protein-glutamate methylesterase activity
Krodi_0913	COG2201	protein-glutamate methylesterase activity
Krodi_0915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Krodi_0916	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Krodi_0919	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Krodi_0921	COG0156	8-amino-7-oxononanoate synthase activity
Krodi_0925	COG3655	Transcriptional regulator
Krodi_0928	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Krodi_0930	COG0297	glycogen (starch) synthase activity
Krodi_0931	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Krodi_0932	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Krodi_0935	COG2197	response regulator
Krodi_0936	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Krodi_0937	COG0739	heme binding
Krodi_0938	COG0667	Aldo Keto reductase
Krodi_0939	COG2885	chlorophyll binding
Krodi_0940	COG0708	Exodeoxyribonuclease III
Krodi_0944	COG0423	glycine-tRNA ligase activity
Krodi_0946	COG1040	competence protein
Krodi_0948	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Krodi_0954	COG0436	Aminotransferase
Krodi_0956	COG1022	Amp-dependent synthetase and ligase
Krodi_0958	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Krodi_0959	COG2095	MarC family integral membrane protein
Krodi_0962	COG0793	Belongs to the peptidase S41A family
Krodi_0966	COG2205	protein histidine kinase activity
Krodi_0966	COG0784	Response regulator, receiver
Krodi_0967	COG0481	GTPase activity
Krodi_0970	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Krodi_0972	COG0527	aspartate kinase activity
Krodi_0976	COG2205	protein histidine kinase activity
Krodi_0977	COG0076	glutamate decarboxylase activity
Krodi_0982	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Krodi_0986	COG2239	Acts as a magnesium transporter
Krodi_0987	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Krodi_0990	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Krodi_0995	COG0196	riboflavin kinase activity
Krodi_0996	COG0193	aminoacyl-tRNA hydrolase activity
Krodi_0997	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Krodi_0998	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Krodi_1003	COG1793	dna ligase
Krodi_1003	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Krodi_1004	COG1793	dna ligase
Krodi_1005	COG2852	Protein conserved in bacteria
Krodi_1006	COG1201	RNA secondary structure unwinding
Krodi_1007	COG0123	including yeast histone deacetylase and acetoin utilization protein
Krodi_1009	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Krodi_1009	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Krodi_1010	COG1619	proteins homologs of microcin C7 resistance protein MccF
Krodi_1011	COG0792	nuclease activity
Krodi_1013	COG0583	DNA-binding transcription factor activity
Krodi_1018	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Krodi_1023	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Krodi_1027	COG0076	glutamate decarboxylase activity
Krodi_1033	COG1418	mRNA catabolic process
Krodi_1036	COG0673	inositol 2-dehydrogenase activity
Krodi_1037	COG1024	Enoyl-CoA hydratase
Krodi_1044	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Krodi_1046	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Krodi_1049	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Krodi_1051	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Krodi_1053	COG0408	coproporphyrinogen oxidase activity
Krodi_1055	COG0113	porphobilinogen synthase activity
Krodi_1058	COG1253	flavin adenine dinucleotide binding
Krodi_1059	COG0784	Response regulator, receiver
Krodi_1059	COG2198	Histidine kinase
Krodi_1059	COG5002	protein histidine kinase activity
Krodi_1060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Krodi_1065	COG4172	Belongs to the ABC transporter superfamily
Krodi_1067	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Krodi_1068	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Krodi_1070	COG1774	PSP1 C-terminal conserved region
Krodi_1072	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Krodi_1073	COG1595	DNA-templated transcription, initiation
Krodi_1076	COG0180	Tryptophanyl-tRNA synthetase
Krodi_1077	COG0720	synthase
Krodi_1078	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Krodi_1079	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Krodi_1079	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Krodi_1084	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Krodi_1088	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Krodi_1091	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Krodi_1093	COG0189	ligase activity
Krodi_1095	COG0322	excinuclease ABC activity
Krodi_1098	COG0469	pyruvate kinase activity
Krodi_1101	COG0571	ribonuclease III activity
Krodi_1102	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Krodi_1103	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Krodi_1105	COG0328	RNA-DNA hybrid ribonuclease activity
Krodi_1105	COG3341	Caulimovirus viroplasmin
Krodi_1108	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Krodi_1109	COG1074	ATP-dependent DNA helicase activity
Krodi_1121	COG2217	Heavy metal translocating P-type atpase
Krodi_1129	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Krodi_1133	COG2217	Heavy metal translocating P-type atpase
Krodi_1137	COG2132	Multicopper oxidase
Krodi_1140	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Krodi_1145	COG0025	NhaP-type Na H and K H
Krodi_1146	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Krodi_1147	COG4412	M6 family metalloprotease domain protein
Krodi_1147	COG1404	Belongs to the peptidase S8 family
Krodi_1151	COG0594	ribonuclease P activity
Krodi_1153	COG0793	Belongs to the peptidase S41A family
Krodi_1154	COG2885	chlorophyll binding
Krodi_1156	COG2153	protein acetylation
Krodi_1157	COG0698	ribose 5-phosphate isomerase
Krodi_1159	COG0557	exoribonuclease II activity
Krodi_1160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Krodi_1160	COG3153	acetyltransferase
Krodi_1164	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
Krodi_1165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Krodi_1171	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Krodi_1173	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Krodi_1174	COG0445	tRNA wobble uridine modification
Krodi_1178	COG0470	DNA polymerase III
Krodi_1179	COG0126	phosphoglycerate kinase activity
Krodi_1180	COG3584	3D domain protein
Krodi_1180	COG1388	LysM domain
Krodi_1183	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Krodi_1184	COG0739	heme binding
Krodi_1188	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Krodi_1189	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Krodi_1191	COG2244	polysaccharide biosynthetic process
Krodi_1195	COG0438	transferase activity, transferring glycosyl groups
Krodi_1196	COG0297	glycogen (starch) synthase activity
Krodi_1197	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Krodi_1199	COG1215	transferase activity, transferring glycosyl groups
Krodi_1201	COG0151	Belongs to the GarS family
Krodi_1206	COG2022	thiamine diphosphate biosynthetic process
Krodi_1207	COG1132	(ABC) transporter
Krodi_1217	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Krodi_1219	COG4152	abc transporter atp-binding protein
Krodi_1224	COG0356	it plays a direct role in the translocation of protons across the membrane
Krodi_1225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Krodi_1226	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Krodi_1227	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Krodi_1228	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Krodi_1229	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Krodi_1232	COG0756	dUTP diphosphatase activity
Krodi_1233	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Krodi_1240	COG0758	DNA mediated transformation
Krodi_1240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Krodi_1242	COG1652	LysM domain
Krodi_1244	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Krodi_1246	COG0194	GDP metabolic process
Krodi_1247	COG1561	YicC-like family, N-terminal region
Krodi_1252	COG0673	inositol 2-dehydrogenase activity
Krodi_1253	COG2211	Major facilitator Superfamily
Krodi_1258	COG2177	Part of the ABC transporter FtsEX involved in
Krodi_1260	COG1968	undecaprenyl-diphosphatase activity
Krodi_1262	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Krodi_1265	COG0519	Catalyzes the synthesis of GMP from XMP
Krodi_1266	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Krodi_1269	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Krodi_1271	COG4260	virion core protein, lumpy skin disease virus
Krodi_1273	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Krodi_1274	COG1764	response to oxidative stress
Krodi_1276	COG2885	chlorophyll binding
Krodi_1277	COG1012	belongs to the aldehyde dehydrogenase family
Krodi_1278	COG0662	Cupin 2, conserved barrel domain protein
Krodi_1280	COG1446	asparaginase
Krodi_1283	COG0517	IMP dehydrogenase activity
Krodi_1283	COG0516	GMP reductase activity
Krodi_1286	COG3590	peptidase
Krodi_1290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Krodi_1292	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Krodi_1293	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Krodi_1295	COG1309	transcriptional regulator
Krodi_1303	COG0626	cystathionine gamma-synthase activity
Krodi_1305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Krodi_1307	COG1381	Involved in DNA repair and RecF pathway recombination
Krodi_1308	COG4771	TonB-dependent receptor
Krodi_1309	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Krodi_1312	COG1435	thymidine kinase activity
Krodi_1313	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Krodi_1314	COG1970	mechanosensitive ion channel activity
Krodi_1315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Krodi_1318	COG1505	serine-type exopeptidase activity
Krodi_1319	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Krodi_1321	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Krodi_1324	COG0659	secondary active sulfate transmembrane transporter activity
Krodi_1331	COG2304	oxidoreductase activity
Krodi_1332	COG2304	oxidoreductase activity
Krodi_1335	COG0714	Associated with various cellular activities
Krodi_1336	COG4989	oxidoreductase activity
Krodi_1337	COG4221	oxidoreductase activity
Krodi_1340	COG3852	Histidine kinase
Krodi_1345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Krodi_1348	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Krodi_1349	COG0495	leucyl-tRNA aminoacylation
Krodi_1351	COG0686	Belongs to the AlaDH PNT family
Krodi_1353	COG3118	belongs to the thioredoxin family
Krodi_1354	COG0740	serine-type endopeptidase activity
Krodi_1360	COG0415	Belongs to the DNA photolyase family
Krodi_1361	COG3046	protein related to deoxyribodipyrimidine photolyase
Krodi_1362	COG0415	Belongs to the DNA photolyase family
Krodi_1365	COG3201	nicotinamide mononucleotide transporter
Krodi_1368	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Krodi_1370	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Krodi_1373	COG1522	sequence-specific DNA binding
Krodi_1375	COG2363	Small membrane protein
Krodi_1376	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Krodi_1378	COG0697	spore germination
Krodi_1381	COG0629	single-stranded DNA binding
Krodi_1385	COG0776	regulation of translation
Krodi_1386	COG1530	ribonuclease E activity
Krodi_1387	COG2137	regulation of response to DNA damage stimulus
Krodi_1390	COG4566	intracellular signal transduction
Krodi_1393	COG0803	Belongs to the bacterial solute-binding protein 9 family
Krodi_1394	COG1121	(ABC) transporter
Krodi_1396	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Krodi_1397	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Krodi_1401	COG1999	signal sequence binding
Krodi_1412	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Krodi_1413	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Krodi_1417	COG4953	penicillin-binding protein 1C
Krodi_1423	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Krodi_1426	COG0668	transmembrane transport
Krodi_1432	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Krodi_1433	COG2814	Major facilitator Superfamily
Krodi_1434	COG1621	beta-fructofuranosidase activity
Krodi_1436	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Krodi_1437	COG1554	hydrolase, family 65, central catalytic
Krodi_1446	COG1629	transport
Krodi_1446	COG4206	TonB-dependent receptor
Krodi_1447	COG0366	Alpha amylase catalytic
Krodi_1448	COG2081	HI0933 family
Krodi_1449	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Krodi_1453	COG1278	Cold shock
Krodi_1455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Krodi_1459	COG0463	Glycosyl transferase, family 2
Krodi_1460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Krodi_1463	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Krodi_1466	COG0745	RESPONSE REGULATOR receiver
Krodi_1467	COG5002	protein histidine kinase activity
Krodi_1469	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Krodi_1472	COG0489	protein tyrosine kinase activity
Krodi_1474	COG0492	ferredoxin-NADP+ reductase activity
Krodi_1486	COG2151	metal-sulfur cluster biosynthetic enzyme
Krodi_1487	COG2166	iron-sulfur cluster assembly
Krodi_1489	COG0456	acetyltransferase
Krodi_1490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Krodi_1491	COG0719	Fe-S assembly protein
Krodi_1492	COG0396	ATPase activity
Krodi_1495	COG0719	Fe-S assembly protein
Krodi_1496	COG0316	Belongs to the HesB IscA family
Krodi_1498	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Krodi_1500	COG4772	TonB-dependent receptor
Krodi_1504	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Krodi_1506	COG2267	carboxylic ester hydrolase activity
Krodi_1509	COG0527	aspartate kinase activity
Krodi_1510	COG0006	proline dipeptidase activity
Krodi_1514	COG1053	succinate dehydrogenase
Krodi_1521	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Krodi_1522	COG1404	Belongs to the peptidase S8 family
Krodi_1523	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Krodi_1528	COG0848	biopolymer transport protein
Krodi_1529	COG1187	pseudouridine synthase activity
Krodi_1530	COG0463	Glycosyl transferase, family 2
Krodi_1534	COG1215	transferase activity, transferring glycosyl groups
Krodi_1535	COG0463	Glycosyl transferase, family 2
Krodi_1539	COG3842	ATPase activity
Krodi_1540	COG1482	cell wall glycoprotein biosynthetic process
Krodi_1543	COG0726	polysaccharide deacetylase
Krodi_1544	COG0861	Integral membrane protein TerC family
Krodi_1548	COG0668	transmembrane transport
Krodi_1549	COG3273	potassium ion transport
Krodi_1549	COG0471	metal ion transport
Krodi_1550	COG0589	response to stress
Krodi_1551	COG0779	Required for maturation of 30S ribosomal subunits
Krodi_1552	COG0195	Participates in both transcription termination and antitermination
Krodi_1553	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Krodi_1556	COG0437	4 iron, 4 sulfur cluster binding
Krodi_1557	COG3743	rRNA binding
Krodi_1557	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Krodi_1561	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Krodi_1562	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Krodi_1563	COG2255	four-way junction helicase activity
Krodi_1565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Krodi_1569	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Krodi_1570	COG0280	phosphate acetyltransferase
Krodi_1570	COG0281	malic enzyme
Krodi_1571	COG0632	four-way junction helicase activity
Krodi_1573	COG0509	glycine decarboxylation via glycine cleavage system
Krodi_1580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Krodi_1581	COG0109	protoheme IX farnesyltransferase activity
Krodi_1582	COG1845	cytochrome c oxidase, subunit III
Krodi_1587	COG2322	membrane
Krodi_1590	COG4206	TonB-dependent receptor
Krodi_1592	COG1136	(ABC) transporter
Krodi_1593	COG0577	efflux transmembrane transporter activity
Krodi_1593	COG1136	(ABC) transporter
Krodi_1594	COG0577	efflux transmembrane transporter activity
Krodi_1594	COG1136	(ABC) transporter
Krodi_1595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Krodi_1597	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Krodi_1598	COG1214	PFAM Peptidase M22, glycoprotease
Krodi_1599	COG0668	transmembrane transport
Krodi_1600	COG0668	transmembrane transport
Krodi_1601	COG1331	Highly conserved protein containing a thioredoxin domain
Krodi_1603	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Krodi_1605	COG1704	LemA family
Krodi_1608	COG0739	heme binding
Krodi_1609	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Krodi_1617	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Krodi_1618	COG0791	NLP P60 protein
Krodi_1618	COG1388	LysM domain
Krodi_1619	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Krodi_1624	COG4682	membrane
Krodi_1627	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_1631	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Krodi_1632	COG2072	flavoprotein involved in K transport
Krodi_1637	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Krodi_1640	COG0321	lipoyl(octanoyl) transferase activity
Krodi_1642	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Krodi_1644	COG0587	DNA-directed DNA polymerase activity
Krodi_1645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Krodi_1646	COG0612	Peptidase, M16
Krodi_1649	COG0772	Belongs to the SEDS family
Krodi_1653	COG1077	Cell shape determining protein MreB Mrl
Krodi_1654	COG0138	bifunctional purine biosynthesis protein purh
Krodi_1668	COG0459	protein refolding
Krodi_1669	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Krodi_1674	COG3829	transcription factor binding
Krodi_1675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Krodi_1682	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Krodi_1688	COG0488	(ABC) transporter
Krodi_1704	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Krodi_1705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Krodi_1709	COG0189	ligase activity
Krodi_1713	COG1294	oxidase, subunit
Krodi_1714	COG1271	oxidase subunit
Krodi_1717	COG0783	Belongs to the Dps family
Krodi_1719	COG0450	alkyl hydroperoxide reductase
Krodi_1721	COG1045	serine acetyltransferase
Krodi_1729	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Krodi_1730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Krodi_1730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Krodi_1731	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Krodi_1731	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Krodi_1732	COG0730	response to heat
Krodi_1737	COG1566	PFAM secretion protein HlyD family protein
Krodi_1742	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Krodi_1746	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Krodi_1747	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Krodi_1754	COG0084	hydrolase, TatD family'
Krodi_1756	COG0252	asparaginase activity
Krodi_1760	COG0811	peptide transport
Krodi_1766	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Krodi_1767	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Krodi_1770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Krodi_1772	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Krodi_1773	COG1663	tetraacyldisaccharide 4'-kinase activity
Krodi_1775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Krodi_1776	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Krodi_1778	COG0799	negative regulation of ribosome biogenesis
Krodi_1779	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Krodi_1781	COG4589	Belongs to the CDS family
Krodi_1782	COG0688	phosphatidylethanolamine metabolic process
Krodi_1784	COG0525	valine-tRNA ligase activity
Krodi_1786	COG0436	Aminotransferase
Krodi_1787	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Krodi_1788	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Krodi_1789	COG1595	DNA-templated transcription, initiation
Krodi_1795	COG0343	queuine tRNA-ribosyltransferase activity
Krodi_1798	COG0825	malonyl-CoA metabolic process
Krodi_1799	COG0305	Participates in initiation and elongation during chromosome replication
Krodi_1800	COG3540	Alkaline phosphatase
Krodi_1804	COG0367	asparagine synthase
Krodi_1807	COG2095	MarC family integral membrane protein
Krodi_1808	COG2003	Belongs to the UPF0758 family
Krodi_1814	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Krodi_1816	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Krodi_1820	COG4206	TonB-dependent receptor
Krodi_1820	COG1629	transport
Krodi_1822	COG1629	transport
Krodi_1822	COG4206	TonB-dependent receptor
Krodi_1825	COG4206	TonB-dependent receptor
Krodi_1825	COG1629	transport
Krodi_1827	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Krodi_1828	COG0049	tRNA binding
Krodi_1829	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Krodi_1830	COG0051	transcription antitermination factor activity, RNA binding
Krodi_1831	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Krodi_1832	COG0088	Forms part of the polypeptide exit tunnel
Krodi_1833	COG0089	rRNA binding
Krodi_1834	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Krodi_1835	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Krodi_1836	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Krodi_1837	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Krodi_1838	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Krodi_1839	COG0255	Belongs to the universal ribosomal protein uL29 family
Krodi_1840	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Krodi_1841	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Krodi_1842	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Krodi_1843	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Krodi_1844	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Krodi_1845	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Krodi_1846	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Krodi_1848	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Krodi_1849	COG1841	ribosomal large subunit assembly
Krodi_1850	COG0200	Binds to the 23S rRNA
Krodi_1851	COG0201	protein transport
Krodi_1852	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Krodi_1853	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Krodi_1854	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Krodi_1855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Krodi_1856	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Krodi_1857	COG0202	RNA polymerase activity
Krodi_1858	COG0203	ribosomal protein L17
Krodi_1860	COG0505	Belongs to the CarA family
Krodi_1862	COG0148	phosphopyruvate hydratase activity
Krodi_1865	COG1834	amidinotransferase
Krodi_1867	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Krodi_1870	COG3239	Fatty acid desaturase
Krodi_1871	COG0357	Ribosomal RNA small subunit methyltransferase G
Krodi_1875	COG0358	DNA primase activity
Krodi_1876	COG2197	response regulator
Krodi_1877	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Krodi_1881	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Krodi_1883	COG2001	Belongs to the MraZ family
Krodi_1884	COG0275	rRNA processing
Krodi_1886	COG0768	penicillin binding
Krodi_1887	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Krodi_1888	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Krodi_1889	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Krodi_1890	COG0772	Belongs to the SEDS family
Krodi_1891	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Krodi_1892	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Krodi_1895	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Krodi_1896	COG1610	YqeY-like protein
Krodi_1897	COG2885	chlorophyll binding
Krodi_1898	COG0666	response to abiotic stimulus
Krodi_1901	COG1595	DNA-templated transcription, initiation
Krodi_1908	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Krodi_1910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Krodi_1911	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Krodi_1915	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_1918	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Krodi_1919	COG2808	Putative FMN-binding domain
Krodi_1920	COG3844	kynureninase activity
Krodi_1923	COG0602	queuosine metabolic process
Krodi_1924	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Krodi_1927	COG0187	DNA topoisomerase II activity
Krodi_1930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Krodi_1931	COG0552	protein localization to endoplasmic reticulum
Krodi_1933	COG0154	amidase activity
Krodi_1934	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Krodi_1937	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Krodi_1943	COG1215	transferase activity, transferring glycosyl groups
Krodi_1947	COG1233	COG1233 Phytoene dehydrogenase and related
Krodi_1948	COG0789	Transcriptional regulator
Krodi_1949	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Krodi_1950	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Krodi_1951	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Krodi_1954	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Krodi_1955	COG3959	Transketolase, thiamine diphosphate binding domain
Krodi_1957	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Krodi_1963	COG3022	response to hydroperoxide
Krodi_1964	COG0564	pseudouridine synthase activity
Krodi_1966	COG1181	Belongs to the D-alanine--D-alanine ligase family
Krodi_1967	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Krodi_1969	COG0159	tryptophan synthase activity
Krodi_1970	COG0133	tryptophan synthase activity
Krodi_1971	COG0135	phosphoribosylanthranilate isomerase activity
Krodi_1973	COG0134	indole-3-glycerol-phosphate synthase activity
Krodi_1974	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Krodi_1976	COG0512	Glutamine amidotransferase of anthranilate synthase
Krodi_1976	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Krodi_1977	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Krodi_1985	COG1858	cytochrome C peroxidase
Krodi_1996	COG0312	modulator of DNA gyrase
Krodi_1999	COG0714	Associated with various cellular activities
Krodi_2008	COG4585	Histidine kinase
Krodi_2010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Krodi_2016	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Krodi_2017	COG0484	heat shock protein binding
Krodi_2018	COG4152	abc transporter atp-binding protein
Krodi_2020	COG1196	nuclear chromosome segregation
Krodi_2020	COG3264	Mechanosensitive ion channel
Krodi_2023	COG2326	polyphosphate kinase activity
Krodi_2027	COG0534	Mate efflux family protein
Krodi_2029	COG0671	phosphoesterase, PA-phosphatase related
Krodi_2030	COG1703	isobutyryl-CoA mutase activity
Krodi_2036	COG0561	phosphatase activity
Krodi_2037	COG0653	protein targeting
Krodi_2041	COG1136	(ABC) transporter
Krodi_2043	COG0488	(ABC) transporter
Krodi_2045	COG0489	protein tyrosine kinase activity
Krodi_2045	COG3206	protein involved in exopolysaccharide biosynthesis
Krodi_2050	COG1216	Glycosyl transferase, family 2
Krodi_2052	COG1216	Glycosyl transferase, family 2
Krodi_2052	COG0463	Glycosyl transferase, family 2
Krodi_2053	COG1215	transferase activity, transferring glycosyl groups
Krodi_2054	COG1216	Glycosyl transferase, family 2
Krodi_2054	COG1442	glycosyl transferase family 8
Krodi_2057	COG3774	pathogenesis
Krodi_2063	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Krodi_2064	COG2089	acid synthase
Krodi_2077	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Krodi_2080	COG0045	succinate-CoA ligase (ADP-forming) activity
Krodi_2082	COG2264	protein methyltransferase activity
Krodi_2085	COG0149	triose-phosphate isomerase activity
Krodi_2089	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Krodi_2091	COG2884	Cell division ATP-binding protein ftsE
Krodi_2093	COG1215	transferase activity, transferring glycosyl groups
Krodi_2095	COG0438	transferase activity, transferring glycosyl groups
Krodi_2102	COG0105	UTP biosynthetic process
Krodi_2103	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Krodi_2105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Krodi_2106	COG2195	Cleaves the N-terminal amino acid of tripeptides
Krodi_2110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Krodi_2111	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Krodi_2112	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Krodi_2113	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Krodi_2117	COG0116	Belongs to the methyltransferase superfamily
Krodi_2120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Krodi_2121	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Krodi_2133	COG0335	large ribosomal subunit rRNA binding
Krodi_2134	COG0268	Binds directly to 16S ribosomal RNA
Krodi_2135	COG0442	prolyl-tRNA aminoacylation
Krodi_2139	COG0366	Alpha amylase catalytic
Krodi_2140	COG1575	Belongs to the MenA family. Type 1 subfamily
Krodi_2141	COG0776	regulation of translation
Krodi_2142	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Krodi_2143	COG0514	ATP-dependent DNA helicase (RecQ)
Krodi_2147	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Krodi_2149	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Krodi_2152	COG2050	protein possibly involved in aromatic compounds catabolism
Krodi_2153	COG1169	isochorismate synthase
Krodi_2154	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Krodi_2156	COG2996	Protein conserved in bacteria
Krodi_2160	COG1363	Peptidase, m42
Krodi_2164	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Krodi_2167	COG1418	mRNA catabolic process
Krodi_2169	COG0137	argininosuccinate synthase activity
Krodi_2170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Krodi_2171	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Krodi_2172	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Krodi_2174	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Krodi_2175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Krodi_2176	COG0165	Argininosuccinate lyase
Krodi_2178	COG0473	3-isopropylmalate dehydrogenase activity
Krodi_2179	COG0066	3-isopropylmalate dehydratase activity
Krodi_2180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Krodi_2181	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Krodi_2184	COG0564	pseudouridine synthase activity
Krodi_2185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Krodi_2188	COG1760	l-serine dehydratase
Krodi_2196	COG0071	Belongs to the small heat shock protein (HSP20) family
Krodi_2198	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Krodi_2200	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Krodi_2201	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Krodi_2204	COG1322	Protein conserved in bacteria
Krodi_2207	COG1120	ATPase activity
Krodi_2215	COG3876	Protein conserved in bacteria
Krodi_2216	COG0577	efflux transmembrane transporter activity
Krodi_2225	COG0659	secondary active sulfate transmembrane transporter activity
Krodi_2230	COG2972	Histidine kinase
Krodi_2231	COG0861	Integral membrane protein TerC family
Krodi_2235	COG1522	sequence-specific DNA binding
Krodi_2237	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Krodi_2239	COG2076	Multidrug Resistance protein
Krodi_2249	COG3344	reverse transcriptase
Krodi_2253	COG0563	adenylate kinase activity
Krodi_2257	COG3344	reverse transcriptase
Krodi_2261	COG4974	Belongs to the 'phage' integrase family
Krodi_2269	COG2169	Transcriptional regulator
Krodi_2269	COG1917	Cupin 2, conserved barrel domain protein
Krodi_2273	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Krodi_2275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Krodi_2279	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Krodi_2280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Krodi_2284	COG1595	DNA-templated transcription, initiation
Krodi_2289	COG0583	DNA-binding transcription factor activity
Krodi_2291	COG0673	inositol 2-dehydrogenase activity
Krodi_2295	COG0598	Magnesium transport protein CorA
Krodi_2297	COG0424	maF-like protein
Krodi_2299	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Krodi_2301	COG1333	cytochrome c biogenesis protein
Krodi_2301	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Krodi_2306	COG0612	Peptidase, M16
Krodi_2308	COG1073	alpha beta
Krodi_2310	COG0012	GTP binding
Krodi_2326	COG2249	NAD(P)H dehydrogenase (quinone) activity
Krodi_2328	COG0210	DNA helicase
Krodi_2329	COG0322	excinuclease ABC activity
Krodi_2333	COG2764	glyoxalase bleomycin resistance protein dioxygenase
Krodi_2338	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Krodi_2347	COG0484	heat shock protein binding
Krodi_2349	COG2198	Histidine kinase
Krodi_2349	COG2205	protein histidine kinase activity
Krodi_2349	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Krodi_2349	COG0784	Response regulator, receiver
Krodi_2350	COG0745	RESPONSE REGULATOR receiver
Krodi_2362	COG0517	IMP dehydrogenase activity
Krodi_2363	COG2217	Heavy metal translocating P-type atpase
Krodi_2366	COG3278	Belongs to the heme-copper respiratory oxidase family
Krodi_2370	COG0348	domain, Protein
Krodi_2376	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Krodi_2377	COG0784	Response regulator, receiver
Krodi_2379	COG4251	negative regulation of phosphorylation
Krodi_2381	COG4251	negative regulation of phosphorylation
Krodi_2383	COG3279	Response regulator of the LytR AlgR family
Krodi_2388	COG2852	Protein conserved in bacteria
Krodi_2396	COG0463	Glycosyl transferase, family 2
Krodi_2397	COG1482	cell wall glycoprotein biosynthetic process
Krodi_2404	COG3275	phosphorelay sensor kinase activity
Krodi_2405	COG3279	Response regulator of the LytR AlgR family
Krodi_2406	COG2070	2-Nitropropane dioxygenase
Krodi_2406	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Krodi_2407	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_2407	COG3321	synthase
Krodi_2407	COG0318	PFAM AMP-dependent synthetase and ligase
Krodi_2407	COG0300	oxidoreductase activity
Krodi_2407	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Krodi_2408	COG4221	oxidoreductase activity
Krodi_2408	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_2408	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Krodi_2408	COG3321	synthase
Krodi_2409	COG3321	synthase
Krodi_2409	COG0604	alcohol dehydrogenase
Krodi_2415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Krodi_2422	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Krodi_2427	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Krodi_2429	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Krodi_2430	COG0714	Associated with various cellular activities
Krodi_2431	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Krodi_2433	COG1733	regulation of RNA biosynthetic process
Krodi_2434	COG0784	Response regulator, receiver
Krodi_2434	COG2205	protein histidine kinase activity
Krodi_2440	COG0069	glutamate synthase activity
Krodi_2444	COG0083	homoserine kinase activity
Krodi_2446	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Krodi_2453	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Krodi_2454	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Krodi_2456	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Krodi_2457	COG0659	secondary active sulfate transmembrane transporter activity
Krodi_2462	COG4977	sequence-specific DNA binding
Krodi_2470	COG0107	imidazoleglycerol-phosphate synthase activity
Krodi_2471	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Krodi_2471	COG0140	phosphoribosyl-ATP diphosphatase activity
Krodi_2476	COG0101	tRNA pseudouridine synthase activity
Krodi_2477	COG0693	protein deglycase activity
Krodi_2485	COG1012	belongs to the aldehyde dehydrogenase family
Krodi_2487	COG3265	gluconokinase activity
Krodi_2488	COG2610	gluconate transmembrane transporter activity
Krodi_2491	COG0714	Associated with various cellular activities
Krodi_2499	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Krodi_2500	COG0577	efflux transmembrane transporter activity
Krodi_2501	COG0124	histidyl-tRNA synthetase
Krodi_2506	COG4206	TonB-dependent receptor
Krodi_2506	COG1629	transport
Krodi_2507	COG3011	Protein conserved in bacteria
Krodi_2509	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Krodi_2511	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Krodi_2512	COG0813	purine-nucleoside phosphorylase activity
Krodi_2516	COG0702	epimerase
Krodi_2517	COG1231	oxidoreductase activity
Krodi_2518	COG2264	protein methyltransferase activity
Krodi_2519	COG0022	dehydrogenase e1 component
Krodi_2522	COG2885	chlorophyll binding
Krodi_2523	COG0644	oxidoreductase
Krodi_2525	COG3424	synthase
Krodi_2526	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_2527	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Krodi_2541	COG2204	response regulator
Krodi_2542	COG1078	dGTPase activity
Krodi_2543	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Krodi_2544	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Krodi_2544	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Krodi_2545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Krodi_2546	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Krodi_2547	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Krodi_2550	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_2556	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Krodi_2557	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Krodi_2558	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Krodi_2559	COG0131	Imidazoleglycerol-phosphate dehydratase
Krodi_2559	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Krodi_2560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Krodi_2561	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Krodi_2564	COG0662	Cupin 2, conserved barrel domain protein
Krodi_2564	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Krodi_2566	COG0433	COG0433 Predicted ATPase
Krodi_2570	COG1132	(ABC) transporter
Krodi_2571	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Krodi_2579	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Krodi_2582	COG1652	LysM domain
Krodi_2582	COG2823	Periplasmic or secreted lipoprotein
Krodi_2586	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Krodi_2591	COG0513	Belongs to the DEAD box helicase family
Krodi_2592	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Krodi_2594	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Krodi_2599	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Krodi_2600	COG3279	Response regulator of the LytR AlgR family
Krodi_2601	COG0360	Binds together with S18 to 16S ribosomal RNA
Krodi_2602	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Krodi_2603	COG0359	binds to the 23S rRNA
Krodi_2605	COG0513	Belongs to the DEAD box helicase family
Krodi_2607	COG1272	protein, Hemolysin III
Krodi_2613	COG0542	response to heat
Krodi_2622	COG1278	Cold shock
Krodi_2624	COG0484	heat shock protein binding
Krodi_2628	COG3590	peptidase
Krodi_2629	COG4221	oxidoreductase activity
Krodi_2631	COG4181	ATPase activity
Krodi_2634	COG1979	alcohol dehydrogenase
Krodi_2635	COG2130	NADP-dependent
Krodi_2637	COG1309	transcriptional regulator
Krodi_2640	COG1278	Cold shock
Krodi_2641	COG0352	thiamine-phosphate diphosphorylase activity
Krodi_2643	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Krodi_2646	COG1047	Peptidyl-prolyl cis-trans
Krodi_2649	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Krodi_2650	COG2022	thiamine diphosphate biosynthetic process
Krodi_2651	COG0352	thiamine-phosphate diphosphorylase activity
Krodi_2653	COG0352	thiamine-phosphate diphosphorylase activity
Krodi_2654	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Krodi_2662	COG2814	Major facilitator Superfamily
Krodi_2664	COG1012	belongs to the aldehyde dehydrogenase family
Krodi_2669	COG1061	Type III restriction enzyme res subunit
Krodi_2673	COG0302	gtp cyclohydrolase
Krodi_2675	COG1136	(ABC) transporter
Krodi_2677	COG2205	protein histidine kinase activity
Krodi_2679	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Krodi_2683	COG0321	lipoyl(octanoyl) transferase activity
Krodi_2683	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Krodi_2686	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Krodi_2687	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Krodi_2690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Krodi_2696	COG2936	dipeptidyl-peptidase activity
Krodi_2697	COG1473	amidohydrolase
Krodi_2703	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Krodi_2704	COG0579	oxidoreductase
Krodi_2705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Krodi_2709	COG1064	alcohol dehydrogenase
Krodi_2711	COG1902	pentaerythritol trinitrate reductase activity
Krodi_2715	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
Krodi_2716	COG1187	pseudouridine synthase activity
Krodi_2717	COG1278	Cold shock
Krodi_2722	COG1132	(ABC) transporter
Krodi_2724	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Krodi_2729	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Krodi_2729	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Krodi_2733	COG1022	Amp-dependent synthetase and ligase
Krodi_2735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Krodi_2736	COG1611	Belongs to the LOG family
Krodi_2739	COG1480	7TM receptor with intracellular HD hydrolase
Krodi_2740	COG0183	Belongs to the thiolase family
Krodi_2741	COG0791	NLP P60 protein
Krodi_2742	COG0457	Tetratricopeptide repeat
Krodi_2743	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Krodi_2744	COG0542	response to heat
Krodi_2747	COG4221	oxidoreductase activity
Krodi_2751	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Krodi_2755	COG4464	protein tyrosine phosphatase activity
Krodi_2758	COG1086	Polysaccharide biosynthesis protein
Krodi_2759	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Krodi_2760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Krodi_2761	COG0110	maltose O-acetyltransferase activity
Krodi_2762	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Krodi_2769	COG1086	Polysaccharide biosynthesis protein
Krodi_2772	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Krodi_2775	COG0189	ligase activity
Krodi_2775	COG4067	protein conserved in archaea
Krodi_2776	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Krodi_2783	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Krodi_2790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Krodi_2792	COG0783	Belongs to the Dps family
Krodi_2794	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Krodi_2800	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Krodi_2802	COG0612	Peptidase, M16
Krodi_2806	COG0628	permease
Krodi_2809	COG1278	Cold shock
Krodi_2810	COG1187	pseudouridine synthase activity
Krodi_2816	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Krodi_2818	COG0405	Gamma-glutamyltransferase
Krodi_2823	COG5002	protein histidine kinase activity
Krodi_2825	COG1250	3-hydroxyacyl-CoA dehydrogenase
Krodi_2825	COG1024	Enoyl-CoA hydratase
Krodi_2827	COG0183	Belongs to the thiolase family
Krodi_2828	COG1960	acyl-CoA dehydrogenase activity
Krodi_2829	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Krodi_2831	COG0494	nUDIX hydrolase
Krodi_2833	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Krodi_2834	COG0366	Alpha amylase catalytic
Krodi_2840	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Krodi_2847	COG0205	6-phosphofructokinase activity
Krodi_2849	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Krodi_2855	COG0248	Ppx GppA phosphatase
Krodi_2856	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Krodi_2858	COG0259	pyridoxamine-phosphate oxidase activity
Krodi_2860	COG1234	tRNA 3'-trailer cleavage
Krodi_2862	COG0540	Belongs to the ATCase OTCase family
Krodi_2863	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Krodi_2867	COG0167	dihydroorotate dehydrogenase activity
Krodi_2868	COG2195	Cleaves the N-terminal amino acid of tripeptides
Krodi_2870	COG3279	Response regulator of the LytR AlgR family
Krodi_2871	COG0402	S-adenosylhomocysteine deaminase activity
Krodi_2876	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Krodi_2879	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Krodi_2890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Krodi_2891	COG4680	protein conserved in bacteria
Krodi_2902	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Krodi_2907	COG0488	(ABC) transporter
Krodi_2909	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Krodi_2910	COG0300	oxidoreductase activity
Krodi_2912	COG0778	Nitroreductase
Krodi_2914	COG2949	membrane
Krodi_2917	COG0592	DNA-directed DNA polymerase activity
Krodi_2918	COG2234	aminopeptidase activity
Krodi_2920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Krodi_2921	COG0626	cystathionine gamma-synthase activity
Krodi_2924	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Krodi_2926	COG4325	translation initiation factor activity
Krodi_2929	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Krodi_2930	COG1741	Belongs to the pirin family
Krodi_2932	COG0393	Putative heavy-metal-binding
Krodi_2940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Krodi_2943	COG0156	8-amino-7-oxononanoate synthase activity
Krodi_2946	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Krodi_2947	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Krodi_2947	COG2885	chlorophyll binding
Krodi_2954	COG0706	membrane insertase activity
Krodi_2955	COG0504	CTP synthase activity
Krodi_2956	COG0516	GMP reductase activity
Krodi_2956	COG0517	IMP dehydrogenase activity
Krodi_2963	COG0513	Belongs to the DEAD box helicase family
Krodi_2965	COG0009	L-threonylcarbamoyladenylate synthase
Krodi_2966	COG0617	tRNA 3'-terminal CCA addition
Krodi_2969	COG0513	Belongs to the DEAD box helicase family
Krodi_2971	COG1131	(ABC) transporter
Krodi_2977	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Krodi_2980	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_2981	COG0415	Belongs to the DNA photolyase family
Krodi_2983	COG1028	Short-chain dehydrogenase reductase Sdr
Krodi_2985	COG1473	amidohydrolase
Krodi_2988	COG0488	(ABC) transporter
Krodi_2990	COG0363	glucosamine-6-phosphate deaminase activity
Krodi_2991	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Krodi_2992	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Krodi_2993	COG4166	transmembrane transport
Krodi_2994	COG1739	Uncharacterized protein family UPF0029