locus-tag class description AB285_00170 ENOG4105E4C Lytic transglycosylase catalytic AB285_00300 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB285_00335 ENOG4105EQR Transposase IS116 IS110 IS902 AB285_00365 ENOG4108C33 Resolvase AB285_00520 ENOG4107YPT transcriptional regulator AB285_00525 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB285_00580 ENOG4105EQR Transposase IS116 IS110 IS902 AB285_00615 ENOG4108C33 Resolvase AB285_00620 ENOG4105EQR Transposase IS116 IS110 IS902 AB285_00670 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG AB285_00675 ENOG4107RJJ Transcriptional regulator AB285_00685 ENOG4105EHI Phosphonate ABC transporter, periplasmic AB285_00690 ENOG4105D5T phosphonate abc transporter AB285_00695 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase AB285_00700 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AB285_00705 ENOG4108F5E vimentin AB285_00710 ENOG4108YIV AB285_00715 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) AB285_00720 ENOG4105CSH Transporter AB285_00725 ENOG4105D7X high-affinity nickel-transporter AB285_00750 ENOG4108R5S membrane AB285_00770 ENOG4108SIC Transcriptional regulator AB285_00775 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) AB285_00785 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AB285_00790 ENOG4108IJ0 Aspartate ammonia-lyase AB285_00795 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 AB285_00800 ENOG4105DVH amino acid AB285_00815 ENOG4105DYB Isoaspartyl dipeptidase AB285_00820 ENOG4108P2H Inner membrane protein YjiG AB285_00825 ENOG41074DU domain protein AB285_00830 ENOG4108ZVF (LipO)protein AB285_00835 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AB285_00850 ENOG4106BSU Entericidin B AB285_00870 ENOG4106FGB Beta-lactamase AB285_00875 ENOG4105ETT transcriptional Regulator, LysR family AB285_00885 ENOG4108WJH Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) AB285_00890 ENOG4105E33 succinate dehydrogenase AB285_00895 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AB285_00900 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) AB285_00905 ENOG4107SC7 Inner membrane transporter yjeM AB285_00945 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AB285_00950 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AB285_00955 ENOG4105K8N protein family UPF0079, ATPase AB285_00960 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AB285_00965 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AB285_00970 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) AB285_00975 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) AB285_00980 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AB285_00985 ENOG4107QJR hflk protein AB285_00990 ENOG4105EPW hflc protein AB285_01005 ENOG4105KPV Transcriptional regulator AB285_01010 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AB285_01015 ENOG4105C2N RNA methyltransferase TrmH family group 3 AB285_01020 ENOG4105CSH Transporter AB285_01025 ENOG4105CSU acyl-Coa dehydrogenase AB285_01030 ENOG4105C8Q Methyl-accepting chemotaxis AB285_01035 ENOG4105S17 UPF0379 protein yjfN AB285_01040 ENOG4105WSB biofilm stress and motility protein A AB285_01045 ENOG4108MXZ Esterase AB285_01060 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC AB285_01090 ENOG4105KIT UPF0379 protein yjfY AB285_01095 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) AB285_01100 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) AB285_01105 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) AB285_01110 ENOG4105K9Q Binds to the 23S rRNA (By similarity) AB285_01115 ENOG4108IPJ Membrane AB285_01120 ENOG4105FHY Opacity-associated protein A AB285_01125 ENOG4108V1T peptidylprolyl cis-trans isomerase AB285_01130 ENOG4105C85 amino acid AB285_01140 ENOG4105C8Q Methyl-accepting chemotaxis AB285_01145 ENOG4105DXC membrane AB285_01155 ENOG4105ECR NmrA family AB285_01160 ENOG4105KVH Transcriptional regulator AB285_01165 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic AB285_01170 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase AB285_01175 ENOG4108UUE Transcriptional regulator AB285_01180 ENOG41061GZ Protein of unknown function (DUF1107) AB285_01185 ENOG4105C37 (CBS) domain AB285_01195 ENOG4107TYG Oxidoreductase domain-containing protein AB285_01215 ENOG4105ETE Transcriptional regulator (LacI family AB285_01220 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) AB285_01225 ENOG4105CFU surface antigen AB285_01230 ENOG4105MA0 exported protein AB285_01235 ENOG4108ZHD aig2 family AB285_01240 ENOG4105F0N pyrophosphate phospho-hydrolase AB285_01245 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator AB285_01250 ENOG4105C2J ABC transporter AB285_01255 ENOG4107R9N ABC transporter AB285_01260 ENOG41062B0 ABC transporter, permease AB285_01265 ENOG4105C8Q Methyl-accepting chemotaxis AB285_01275 ENOG4105DFU Cell wall formation (By similarity) AB285_01280 ENOG4105N42 UPF0307 protein AB285_01285 ENOG4105CMS peptidase U62, modulator of DNA gyrase AB285_01290 ENOG4108XVM Cytochrome b(562) AB285_01325 ENOG41069H0 dihydroorotase EC 3.5.2.3 AB285_01345 ENOG4105EMD TRANSCRIPTIONal AB285_01350 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) AB285_01355 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase AB285_01360 ENOG4105DM4 PTS System AB285_01365 ENOG4105C8I hydrolase, family 38 AB285_01370 ENOG410863U PTS System AB285_01380 ENOG4105CG3 alpha amylase, catalytic region AB285_01385 ENOG4105C5Y PTS System AB285_01390 ENOG4105D4X repressor AB285_01400 ENOG4105E2D ec 3.2.1.52 AB285_01405 ENOG4108M1A Chitin-binding protein AB285_01410 ENOG4105KME endoribonuclease L-psp AB285_01415 ENOG4108R9M Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity) AB285_01420 ENOG4105CXT aspartate transcarbamylase AB285_01425 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) AB285_01430 ENOG4105CSX c4-dicarboxylate anaerobic carrier AB285_01435 ENOG4105DBV ornithine carbamoyltransferase AB285_01440 ENOG4105C5B carbamate kinase AB285_01445 ENOG4105CEU Arginine dihydrolase AB285_01450 ENOG4105XEP YhcH YjgK YiaL family protein AB285_01455 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB285_01460 ENOG4105C01 Dihydroxy-acid dehydratase AB285_01465 ENOG4105CT4 transporter AB285_01470 ENOG4105DSG hydrolase family 43 AB285_01475 ENOG4107HP6 Transcriptional regulator AB285_01490 ENOG4105DBV ornithine carbamoyltransferase AB285_01495 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) AB285_01500 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase AB285_01535 ENOG4105ZTC transcriptional activator, Ogr delta AB285_01630 ENOG4105ETE Transcriptional regulator (LacI family AB285_01640 ENOG4105CT4 transporter AB285_01685 ENOG4105BZU Histidine kinase AB285_01690 ENOG4108ZXC Two component transcriptional regulator, luxr family AB285_01695 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase AB285_01700 ENOG4108S10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AB285_01705 ENOG4105EZE Cupin 4 family protein AB285_01730 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB285_01735 ENOG4106DIZ Domain of unknown function (DUF1127) AB285_01745 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AB285_01755 ENOG4108ZHR arsR family transcriptional regulator AB285_01765 ENOG4105ENT Efflux transporter rnd family, mfp subunit AB285_01775 ENOG4106BRA Membrane AB285_01790 ENOG4105C26 Dehydrogenase AB285_01805 ENOG4105X1N Glycosyl transferase family 8 AB285_01810 ENOG4105PF3 O-Antigen polymerase AB285_01815 ENOG4105CKI cobalamin synthesis protein AB285_01820 ENOG4105VCD cytoplasmic protein AB285_01825 ENOG4105D22 carbon starvation protein AB285_01830 ENOG4105YW5 deoR family transcriptional regulator AB285_01835 ENOG4107UWN reductase AB285_01840 ENOG4105EFA 4-hydroxyphenylacetate AB285_01855 ENOG4105CNV Aldolase AB285_01870 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase AB285_01875 ENOG4105C26 Dehydrogenase AB285_01880 ENOG4105ERH Fumarylacetoacetate hydrolase AB285_01885 ENOG4108V8F Transcriptional regulator, MarR family AB285_01890 ENOG4105C8Q Methyl-accepting chemotaxis AB285_01895 ENOG4105XYF acetyltransferase AB285_01900 ENOG4107RES phosphoglycerol transferase I AB285_01905 ENOG4105RI1 glycoprotein receptor AB285_01910 ENOG4106CVF DNA replication protein AB285_01915 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) AB285_01920 ENOG4108ZHJ Organic hydroperoxide resistance protein AB285_01925 ENOG4105K56 Transcriptional regulator AB285_01930 ENOG4107XM3 UPF0442 protein AB285_01935 ENOG4105DWK Membrane AB285_01940 ENOG4108N8T regulatoR AB285_01945 ENOG4108T94 DNA-binding transcriptional activator BglJ AB285_01950 ENOG4108UIN ybak prolyl-trna synthetase associated region AB285_01955 ENOG4105CK1 PTS System AB285_01960 ENOG4108819 ferric iron reductase AB285_01965 ENOG4106TD9 Diguanylate cyclase AB285_01970 ENOG4105YBH Protein of unknown function (DUF1435) AB285_01990 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) AB285_01995 ENOG4108WPU DNA polymerase III subunit psi AB285_02000 ENOG4105KEG ribosomal-protein-alanine acetyltransferase AB285_02005 ENOG4105PAD Hydrolase AB285_02010 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) AB285_02015 ENOG4105K3G Periplasmic Protein AB285_02025 ENOG4108NRW Phospholipase, patatin family AB285_02030 ENOG4105EYA deoxyribonuclease AB285_02035 ENOG41076CZ activating enzyme AB285_02040 ENOG4105G0K glycine radical enzyme YjjI family AB285_02050 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) AB285_02060 ENOG4105D3A purine nucleoside phosphorylase DeoD-type AB285_02065 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) AB285_02070 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) AB285_02075 ENOG4105EAC phosphoserine phosphatase AB285_02080 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AB285_02085 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase AB285_02100 ENOG4105C5H ABC transporter AB285_02105 ENOG4107SC1 transglycosylase AB285_02110 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) AB285_02115 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AB285_02120 ENOG4105CVJ phosphoglycerate mutase AB285_02125 ENOG4105UEI Transcriptional Regulator AraC Family AB285_02130 ENOG4108RH0 Crea protein AB285_02135 ENOG41065U4 response regulator AB285_02140 ENOG4106FVC RNA methyltransferase AB285_02145 ENOG4105CFH Aspartokinase AB285_02155 ENOG4105D98 threonine synthase AB285_02160 ENOG41062C6 Protein of unknown function (DUF2502) AB285_02165 ENOG4105D1Q UPF0246 protein AB285_02170 ENOG4105BZG amino acid carrier protein AB285_02180 ENOG4108RIR Molybdenum cofactor biosynthesis protein AB285_02185 ENOG4105CSH Transporter AB285_02190 ENOG4106HK8 GPR1 FUN34 yaaH family protein AB285_02200 ENOG4105CFG Acts as a chaperone (By similarity) AB285_02205 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) AB285_02210 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AB285_02215 ENOG41063Z6 transcriptional regulator, lysR family AB285_02220 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) AB285_02225 ENOG4105DTN riboflavin biosynthesis protein ribF AB285_02230 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AB285_02240 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase AB285_02245 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) AB285_02260 ENOG4105F3R pts system mannose fructose sorbose family iid AB285_02265 ENOG4105ETZ PTS System AB285_02270 ENOG4108IQ3 PTS system AB285_02285 ENOG4107P2S Transcriptional regulator AB285_02290 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) AB285_02295 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AB285_02300 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AB285_02305 ENOG4105M5B (LipO)protein AB285_02320 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB285_02325 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) AB285_02330 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) AB285_02335 ENOG4105NWN ApaG protein AB285_02340 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AB285_02345 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) AB285_02350 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) AB285_02355 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) AB285_02360 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) AB285_02365 ENOG4105D3G Pseudouridine synthase AB285_02370 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) AB285_02375 ENOG4105CQ2 DNA polymerase AB285_02380 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AB285_02385 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) AB285_02390 ENOG4105EF1 ribulokinase AB285_02400 ENOG4108KF1 Membrane AB285_02410 ENOG4106SMU thiamine transporter membrane protein AB285_02415 ENOG4105DP9 ABC transporter AB285_02430 ENOG4105S8Q sugar efflux transporter AB285_02435 ENOG41060TC Hok gef cell toxic protein AB285_02440 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AB285_02450 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AB285_02455 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AB285_02460 ENOG41064T2 transcriptional regulator, lysR family AB285_02465 ENOG4105C7K acetolactate synthase AB285_02470 ENOG4108ZP8 Acetolactate synthase small subunit AB285_02475 ENOG4107B7Y DNA-binding transcriptional regulator FruR AB285_02480 ENOG4108V6E Cell division protein mraZ AB285_02490 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AB285_02495 ENOG4105CJN penicillin-binding protein AB285_02500 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AB285_02505 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) AB285_02510 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) AB285_02520 ENOG4105CNI cell division protein FtsW AB285_02525 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AB285_02530 ENOG4105DFU Cell wall formation (By similarity) AB285_02535 ENOG4105CPF Cell wall formation (By similarity) AB285_02540 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) AB285_02545 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AB285_02550 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AB285_02555 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB285_02560 ENOG4106Q9Y Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) AB285_02565 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving AB285_02570 ENOG4105M6F mutator MutT protein AB285_02575 ENOG41067SF Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) AB285_02580 ENOG4105DHA Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity) AB285_02585 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AB285_02590 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AB285_02595 ENOG4105D7Q type ii secretion system AB285_02600 ENOG4107QHF type ii secretion system protein e AB285_02605 ENOG4108ZUW Major pilin subunit AB285_02610 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AB285_02615 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AB285_02620 ENOG4106A72 regulatory protein AmpE AB285_02625 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) AB285_02630 ENOG4105CT4 transporter AB285_02635 ENOG4105C85 amino acid AB285_02645 ENOG41073TP transcriptional regulator AB285_02650 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AB285_02655 ENOG4107QSN dihydrolipoamide acetyltransferase AB285_02660 ENOG4107QN2 dihydrolipoyl dehydrogenase AB285_02670 ENOG4108NST exported protein AB285_02675 ENOG4107QIJ Aconitate hydratase 2 AB285_02685 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) AB285_02690 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) AB285_02695 ENOG4108ZRK uncharacterized protein yacC AB285_02700 ENOG4105E3B Multicopper oxidase AB285_02705 ENOG4105DZG Dehydrogenase AB285_02710 ENOG4108UGV hypoxanthine phosphoribosyltransferase AB285_02715 ENOG41077A9 carbonic anhydrase AB285_02720 ENOG4105DA5 (ABC) transporter AB285_02725 ENOG4105E3A (ABC) transporter AB285_02730 ENOG4108YTN IIa component AB285_02735 ENOG4107BJW polysaccharide deacetylase AB285_02755 ENOG4108XEY fimbrial-like adhesin protein AB285_02760 ENOG4105CW0 outer membrane usher protein AB285_02765 ENOG4108VEV chaperone AB285_02775 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) AB285_02780 ENOG4107R03 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) AB285_02785 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) AB285_02790 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AB285_02795 ENOG4105DJ0 Poly(A) Polymerase AB285_02800 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) AB285_02805 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters AB285_02810 ENOG4105PW4 Sugar fermentation stimulation protein homolog AB285_02815 ENOG4107XID 2'-5' rna ligase AB285_02820 ENOG4105CQ7 ATP-dependent helicase AB285_02825 ENOG4105BZ4 penicillin-binding protein AB285_02835 ENOG4108NAE Fimbrial chaperone protein AB285_02840 ENOG4105CW0 outer membrane usher protein AB285_02850 ENOG4105E0K tonB-dependent siderophore receptor AB285_02855 ENOG4105E0A ABC, transporter AB285_02860 ENOG4105J76 Periplasmic binding protein AB285_02865 ENOG4105S6R Iron-hydroxamate transporter permease subunit AB285_02870 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase AB285_02875 ENOG4105CMQ Chloride channel AB285_02880 ENOG4108YX9 iron--sulfur cluster insertion protein erpA AB285_02885 ENOG4105EN6 Membrane AB285_02890 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) AB285_02895 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) AB285_02900 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein AB285_02905 ENOG4105C0H protease AB285_02910 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR AB285_02915 ENOG4108T8E UPF0325 protein AB285_02920 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) AB285_02925 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) AB285_02930 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AB285_02940 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) AB285_02945 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) AB285_02955 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AB285_02965 ENOG4105KNE Phosphatidate cytidylyltransferase AB285_02970 ENOG4105DZP Membrane-associated zinc metalloprotease AB285_02975 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AB285_02985 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB285_02990 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) AB285_02995 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB285_03000 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB285_03005 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AB285_03010 ENOG4105C0B DNA polymerase III (alpha subunit) AB285_03015 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) AB285_03020 ENOG4105CXN decarboxylase AB285_03025 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase AB285_03030 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AB285_03035 ENOG4105M1T rho-binding antiterminator AB285_03040 ENOG4105W1I UPF0253 protein AB285_03045 ENOG4108VWS Yaeq family AB285_03050 ENOG4108YZN class I peptide chain release factor AB285_03055 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion AB285_03060 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) AB285_03065 ENOG4108R96 Methyltransferase, YaeB family AB285_03070 ENOG4108R8X outer membrane lipoprotein AB285_03075 ENOG4105D01 (LipO)protein AB285_03080 ENOG4108UMI ABC transporter, permease AB285_03085 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AB285_03090 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase AB285_03125 ENOG4105CV8 reductase AB285_03130 ENOG4105HEI LysR family (Transcriptional regulator AB285_03135 ENOG4105F27 Major Facilitator AB285_03140 ENOG4107NA1 Endonuclease Exonuclease phosphatase AB285_03145 ENOG4105F2W methyltransferase AB285_03150 ENOG4105E9H Lytic Murein transglycosylase AB285_03155 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB285_03160 ENOG4105D1A Methyltransferase AB285_03170 ENOG4108JDX DNA polymerase iii, epsilon subunit AB285_03185 ENOG4105C3U ABC transporter AB285_03190 ENOG4108JQ7 (ABC) transporter AB285_03195 ENOG4105DEF Extracellular solute-binding protein, family 5 AB285_03205 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB285_03210 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AB285_03215 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AB285_03220 ENOG4107QPN acyl-Coa dehydrogenase AB285_03230 ENOG4105E7A Glutamine amidotransferase AB285_03235 ENOG4105F7V ErfK ybiS ycfS ynhG family protein AB285_03240 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AB285_03250 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AB285_03255 ENOG4105F5D NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AB285_03260 ENOG4108IUB NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AB285_03265 ENOG4105D26 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity) AB285_03275 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AB285_03280 ENOG4105CIN aminoacyl-histidine dipeptidase AB285_03285 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) AB285_03290 ENOG4105V1F Fermentation respiration switch protein AB285_03300 ENOG4105FCK Membrane AB285_03305 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AB285_03310 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) AB285_03395 ENOG4105F2I Transposase AB285_03415 ENOG4105F4G Membrane AB285_03420 ENOG4108IQI permease AB285_03425 ENOG4107QK5 Homocysteine s-methyltransferase AB285_03430 ENOG4106FTQ Taurine ABC transporter, periplasmic AB285_03435 ENOG4108ETV ABC transporter AB285_03440 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AB285_03445 ENOG4105E2B Taurine dioxygenase AB285_03455 ENOG4105D52 delta-aminolevulinic acid dehydratase AB285_03465 ENOG4108NSE outer membrane autotransporter barrel AB285_03470 ENOG4108PNB DNA-binding transcriptional regulator AB285_03475 ENOG4107R6D beta-lactam binding protein AmpH AB285_03480 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 AB285_03485 ENOG4107QS8 (LipO)protein AB285_03490 ENOG4105FR5 inner membrane protein YaiY AB285_03495 ENOG4105UNH Membrane AB285_03500 ENOG4105CPF Cell wall formation (By similarity) AB285_03515 ENOG4105RZQ Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (By similarity) AB285_03520 ENOG4105VIF phosphate starvation-inducible protein AB285_03530 ENOG4105II7 pyrroline-5-carboxylate reductase AB285_03535 ENOG4108UPT UPF0178 protein AB285_03540 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) AB285_03545 ENOG4105SS3 AB285_03550 ENOG4105HBA AroM protein AB285_03555 ENOG4105NBK UPF0345 protein AB285_03565 ENOG4105DKQ ROK family AB285_03570 ENOG4105EYH Exonuclease AB285_03575 ENOG4107RH8 nuclease SbcCD subunit D AB285_03585 ENOG4105BZU Histidine kinase AB285_03590 ENOG4105CWM branched-chain amino acid transport system II carrier protein AB285_03595 ENOG4105C85 amino acid AB285_03600 ENOG4107R28 alpha amylase, catalytic region AB285_03615 ENOG4105D3R alkyl hydroperoxide reductase AB285_03620 ENOG4108ZYK Acyl carrier protein phosphodiesterase AB285_03630 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) AB285_03635 ENOG4105VIE preprotein translocase, subunit YajC AB285_03640 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB285_03645 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB285_03660 ENOG4105DRB nucleoside-specific channel-forming protein AB285_03665 ENOG4108KIC (LipO)protein AB285_03670 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) AB285_03675 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AB285_03680 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) AB285_03685 ENOG4107YIM Involved in the transcription termination process (By similarity) AB285_03690 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AB285_03695 ENOG4105CPC Aldo Keto reductase AB285_03700 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) AB285_03705 ENOG4105CTB Polyprenyl synthetase AB285_03710 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AB285_03720 ENOG4105FDP GntR family transcriptional regulator AB285_03725 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) AB285_03730 ENOG4105F8D glycoside hydrolase family 4 AB285_03735 ENOG4105CK1 PTS System AB285_03740 ENOG4107S0N DJ-1 family AB285_03745 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) AB285_03755 ENOG4107RDB Major Facilitator AB285_03760 ENOG4107W7X Aldolase AB285_03770 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AB285_03780 ENOG4105CNN ABC, transporter AB285_03785 ENOG4105C2J ABC transporter AB285_03790 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) AB285_03795 ENOG4105CMG Carbohydrate kinase AB285_03805 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) AB285_03810 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) AB285_03815 ENOG4105CCU oxidase (Subunit III) AB285_03820 ENOG4105BZ9 Cytochrome C oxidase, subunit I AB285_03825 ENOG4105E2S oxidase) subunit II AB285_03835 ENOG4105EYM Major Facilitator superfamily AB285_03840 ENOG4105IEY (LipO)protein AB285_03845 ENOG4105M85 Bola protein AB285_03850 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation AB285_03865 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AB285_03870 ENOG4105K70 DNA-binding protein AB285_03875 ENOG4105EIN peptidylprolyl cis-trans isomerase AB285_03880 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein AB285_03885 ENOG4108TGP Thioesterase superfamily protein AB285_03890 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) AB285_03895 ENOG4108NFA extracellular solute-binding protein AB285_03900 ENOG4108AZI Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity) AB285_03910 ENOG4108XM1 transcriptional regulator AsnC family AB285_03915 ENOG4105BZ1 (ABC) transporter AB285_03920 ENOG4105BZ1 (ABC) transporter AB285_03925 ENOG4108YZA Nitrogen regulatory protein pii AB285_03930 ENOG4105BZU Histidine kinase AB285_03935 ENOG4105C29 acyl-CoA thioesterase AB285_03940 ENOG4108MNP Glycoprotein polysaccharide metabolism AB285_03945 ENOG41080UX Methyltransferase AB285_03960 ENOG4107U9B transcriptional regulator AB285_03965 ENOG4108VW9 Membrane AB285_03970 ENOG4105ETE Transcriptional regulator (LacI family AB285_03980 ENOG41061MD high-affinity nickel-transporter AB285_03990 ENOG41066DG (EAL) domain protein AB285_03995 ENOG4105NRA 50s ribosomal protein l31 type b AB285_04000 ENOG4105YK5 50S ribosomal protein L36 AB285_04015 ENOG4105GSJ Inner membrane protein ylaC AB285_04020 ENOG4108UW5 maltose o-acetyltransferase AB285_04030 ENOG4108UKR Biofilm formation regulator YbaJ AB285_04035 ENOG4105BZS acriflavin resistance protein AB285_04040 ENOG4105C1P efflux transporter, rnd family, mfp subunit AB285_04045 ENOG4108IG5 Transcriptional regulator AB285_04050 ENOG4105EGS Mechanosensitive ion channel AB285_04060 ENOG4108URS primosomal replication protein n'' AB285_04065 ENOG4105WD1 Membrane AB285_04070 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) AB285_04075 ENOG4107QMP dna polymerase iii subunits gamma and tau AB285_04080 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) AB285_04085 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) AB285_04090 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AB285_04100 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AB285_04105 ENOG4107RE1 Inosine-guanosine kinase AB285_04110 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB285_04115 ENOG4105EU0 Major facilitator Superfamily AB285_04120 ENOG4105CGH 5'-nucleotidase AB285_04125 ENOG4108Z66 YbaK ebsC protein AB285_04130 ENOG4105MBR gumn family AB285_04135 ENOG4105C59 p-type ATPase AB285_04140 ENOG4108Z6Z Transcriptional regulator AB285_04145 ENOG4105G5H Membrane AB285_04150 ENOG4107QX8 SPFH domain, Band 7 family protein AB285_04160 ENOG41083J0 (ABC) transporter AB285_04165 ENOG4105C4B ABC transporter, permease AB285_04170 ENOG4107QR8 Thioredoxin AB285_04175 ENOG4105E1F short-chain dehydrogenase reductase AB285_04180 ENOG4108UJV acyl-CoA thioesterase i AB285_04185 ENOG4108I0Y (ABC) transporter AB285_04190 ENOG4105CV6 ABC transporter, permease AB285_04205 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AB285_04210 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AB285_04215 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) AB285_04220 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AB285_04225 ENOG4105C8N cysteinyl-tRNA synthetase AB285_04230 ENOG4105S2T inner membrane protein YbcI AB285_04235 ENOG4107P2S Transcriptional regulator AB285_04240 ENOG4105CI1 PTS System AB285_04245 ENOG4105WQ3 Rna-binding protein AB285_04255 ENOG4108WDE Fimbrial protein AB285_04260 ENOG4105NJT Fimbrial protein AB285_04265 ENOG4108AF8 Chaperone AB285_04270 ENOG4105CW0 outer membrane usher protein AB285_04275 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) AB285_04280 ENOG4108ZI2 Fimbrial protein AB285_04285 ENOG4108Q9V regulatoR AB285_04305 ENOG4105TDT uncharacterized protein yahO AB285_04320 ENOG4105C85 amino acid AB285_04325 ENOG4105EAA nucleoside AB285_04340 ENOG4105ETE Transcriptional regulator (LacI family AB285_04345 ENOG4105CUY Mechanosensitive ion channel AB285_04375 ENOG4105HFT AraC family transcriptional regulator AB285_04390 ENOG4105WQ6 Membrane AB285_04400 ENOG4105ENT Efflux transporter rnd family, mfp subunit AB285_04410 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) AB285_04435 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) AB285_04445 ENOG4105WPN DNA integration recombination invertion protein AB285_04460 ENOG4105C7K acetolactate synthase AB285_04465 ENOG4105CHR reductase AB285_04475 ENOG4108JQ7 (ABC) transporter AB285_04480 ENOG4105C3U ABC transporter AB285_04485 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB285_04490 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB285_04520 ENOG4105C94 Transporter AB285_04550 ENOG4105DIK (ABC) transporter AB285_04555 ENOG4105CC5 ABC transporter AB285_04560 ENOG4105CC5 ABC transporter AB285_04565 ENOG4108TSE Transferase AB285_04570 ENOG4107RNH Outer membrane receptor FepA AB285_04575 ENOG4105E93 esterase AB285_04580 ENOG41085A6 mbth domain-containing protein AB285_04585 ENOG4105C0W non-ribosomal peptide synthetase AB285_04590 ENOG4105E0A ABC, transporter AB285_04595 ENOG4105TVJ transport system, permease AB285_04600 ENOG4105DQ5 transport system permease protein AB285_04605 ENOG4105E8G Major facilitator Superfamily AB285_04610 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein AB285_04615 ENOG4105E4F Isochorismate synthase AB285_04620 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AB285_04625 ENOG4105WQI isochorismatase AB285_04630 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase AB285_04635 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) AB285_04640 ENOG4105D22 carbon starvation protein AB285_04645 ENOG4105VCD cytoplasmic protein AB285_04660 ENOG4105CHR reductase AB285_04665 ENOG4107SCQ Iron-containing alcohol dehydrogenase AB285_04670 ENOG4105C2J ABC transporter AB285_04675 ENOG4105CNN ABC, transporter AB285_04690 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) AB285_04695 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) AB285_04705 ENOG4105HVQ Regulatory factor of maltose metabolism AB285_04720 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) AB285_04725 ENOG4106YVY Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity) AB285_04730 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) AB285_04735 ENOG4105CHM Aminotransferase AB285_04740 ENOG4105GTN ParB Domain Protein Nuclease AB285_04745 ENOG4105BZV Phosphoadenosine phosphosulfate reductase AB285_04750 ENOG4105DQS Transcriptional regulator AB285_04755 ENOG4105D3R alkyl hydroperoxide reductase AB285_04760 ENOG4108JU3 Alkyl hydroperoxide reductase AB285_04765 ENOG4108U51 Universal stress protein AB285_04770 ENOG4105E2A Dehydrogenase AB285_04775 ENOG4105NXH GreA GreB family elongation factor AB285_04785 ENOG4108CIP transcriptional regulator AB285_04790 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AB285_04795 ENOG4105CN9 Peptidase m42 family protein AB285_04800 ENOG4105DC7 peptidase M24 AB285_04805 ENOG410863U PTS System AB285_04810 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) AB285_04815 ENOG4105KTS ribonuclease AB285_04820 ENOG4105CEE C4-dicarboxylate transporter AB285_04840 ENOG4105EP1 Efflux transporter rnd family, mfp subunit AB285_04845 ENOG4108IJF Heavy metal efflux pump, CzcA AB285_04855 ENOG4105VEQ Cold shock protein AB285_04865 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AB285_04870 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) AB285_04875 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AB285_04880 ENOG41064T2 transcriptional regulator, lysR family AB285_04885 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) AB285_04895 ENOG4105DZ1 carboxypeptidase AB285_04900 ENOG4105K6T rare lipoprotein A AB285_04905 ENOG4105CNI cell division protein FtsW AB285_04910 ENOG4105CJN penicillin-binding protein AB285_04920 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) AB285_04925 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) AB285_04930 ENOG4105DJF DNA polymerase III, delta' subunit AB285_04940 ENOG4105C8T Leucyl-tRNA synthetase AB285_04945 ENOG4107PAI alpha helical protein AB285_04950 ENOG4105DU0 nucleoside hydrolase AB285_04955 ENOG4105CDA abc transporter atp-binding protein AB285_04960 ENOG4105DRP amino acid AbC transporter AB285_04965 ENOG4105EAD ABC transporter AB285_04970 ENOG4107RP9 extracellular solute-binding protein, family 3 AB285_04975 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) AB285_04980 ENOG4108JU5 Magnesium and cobalt efflux protein AB285_04985 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) AB285_04990 ENOG4105C9A Phoh family AB285_04995 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AB285_05000 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AB285_05040 ENOG4105CAQ asparagine synthetase AB285_05045 ENOG4105D4U had-superfamily hydrolase, subfamily iia AB285_05050 ENOG4105E2R ROK family AB285_05055 ENOG4105CE4 GlcNAc 6-P deacetylase AB285_05065 ENOG4105CI1 PTS System AB285_05080 ENOG4105GX6 (LipO)protein AB285_05085 ENOG41090R7 Ferric uptake AB285_05090 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) AB285_05095 ENOG4105NNH LexA regulated protein AB285_05100 ENOG4105EV9 Alpha Beta Hydrolase AB285_05105 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) AB285_05110 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 AB285_05115 ENOG4105D5Q Arginine ornithine antiporter AB285_05120 ENOG4105CXN decarboxylase AB285_05125 ENOG4105EEX Two component transcriptional regulator (Winged helix family AB285_05130 ENOG4105C08 Histidine kinase AB285_05135 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) AB285_05140 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB285_05145 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB285_05155 ENOG4105XIQ Protein of unknown function (DUF2517) AB285_05160 ENOG4105CVP deoxyribo-dipyrimidine photolyase AB285_05165 ENOG4107QNR UPF0135 protein AB285_05170 ENOG4105P4J Allophanate hydrolase, subunit 1 AB285_05175 ENOG4107R7A Allophanate hydrolase subunit 2 AB285_05180 ENOG4105E7W lamb ycsf family protein AB285_05185 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) AB285_05190 ENOG4105BZN citrate synthase AB285_05195 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit AB285_05200 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein AB285_05205 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AB285_05210 ENOG4105E33 succinate dehydrogenase AB285_05215 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 AB285_05220 ENOG4105C7S Dehydrogenase AB285_05225 ENOG4105CMV Succinyl-CoA synthetase subunit beta AB285_05230 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AB285_05235 ENOG4105FDP GntR family transcriptional regulator AB285_05240 ENOG4105DM4 PTS System AB285_05245 ENOG4105C8I hydrolase, family 38 AB285_05250 ENOG4105C4M (Ubiquinol oxidase) subunit I AB285_05255 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB285_05265 ENOG4105KJB cyd operon protein YbgE AB285_05270 ENOG4107YD3 Thioesterase AB285_05275 ENOG4105E02 MotA TolQ exbB proton channel AB285_05280 ENOG4105M8F Biopolymer transport protein exbD tolR AB285_05285 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA AB285_05290 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) AB285_05295 ENOG4105KCK Peptidoglycan-associated lipoprotein AB285_05300 ENOG4105UFD tol-pal system protein YbgF AB285_05335 ENOG4106Z1T Nicotinamide Mononucleotide Transporter AB285_05340 ENOG4105PGM cation diffusion facilitator family transporter AB285_05345 ENOG4105JND homeobox protein AB285_05350 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB285_05360 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) AB285_05365 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) AB285_05370 ENOG4105F0Z galactose-1-phosphate uridylyltransferase AB285_05375 ENOG4105CMR udp-glucose 4-epimerase AB285_05380 ENOG4105DKW ABC transporter AB285_05385 ENOG4105F4R Transcriptional regulator mode AB285_05390 ENOG410680R Protein of unknown function (DUF2592) AB285_05395 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AB285_05400 ENOG4105E0C molybdate abc transporter AB285_05410 ENOG4108K4B hydrolase AB285_05415 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) AB285_05420 ENOG4105NBR Pectinesterase AB285_05425 ENOG4105CI2 imidazolone-5-propionate hydrolase AB285_05430 ENOG41088SP formiminoglutamate hydrolase AB285_05440 ENOG4105CGP Urocanate hydratase AB285_05445 ENOG4105C84 Histidine ammonia-lyase AB285_05450 ENOG4108V1U phospholipid-binding protein AB285_05455 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AB285_05460 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) AB285_05465 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AB285_05470 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AB285_05490 ENOG4105CHW UPF0052 protein AB285_05500 ENOG4108RIR Molybdenum cofactor biosynthesis protein AB285_05505 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB285_05510 ENOG4105M00 molybdopterin converting factor, subunit 1 AB285_05515 ENOG4108ZAF Molybdopterin AB285_05520 ENOG4105HFZ Membrane AB285_05525 ENOG4107UXM Membrane AB285_05530 ENOG4105DZQ phospholipase D Transphosphatidylase AB285_05535 ENOG4105X23 Endonuclease Exonuclease phosphatase AB285_05540 ENOG4105I9U inner membrane protein ybhQ AB285_05545 ENOG4107QWP ABC-2 type transporter AB285_05550 ENOG4107QWP ABC-2 type transporter AB285_05555 ENOG4105CJ1 ABC, transporter AB285_05560 ENOG4105D0S secretion protein (HlyD AB285_05565 ENOG4107MVR Transcriptional regulator AB285_05570 ENOG4105C1J atp-dependent rna helicase AB285_05575 ENOG4105DVT helicase AB285_05590 ENOG4105CW0 outer membrane usher protein AB285_05595 ENOG4108VCD Chaperone AB285_05600 ENOG4105MX3 Fimbrial AB285_05605 ENOG4108MTB glycosyl transferase family AB285_05610 ENOG4105VR4 UPF0379 protein ybiJ AB285_05615 ENOG4105KSC Transcriptional regulator, TraR DksA family AB285_05620 ENOG4105ZY9 UPF0379 protein ybiM AB285_05630 ENOG4105EBA Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity) AB285_05635 ENOG4105D8X mechanosensitive ion channel AB285_05640 ENOG4105CDA abc transporter atp-binding protein AB285_05645 ENOG4105E5Q amino acid AbC transporter AB285_05650 ENOG4107R0W ABC transporter AB285_05655 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction AB285_05665 ENOG4108T1M outer membrane protein x AB285_05670 ENOG4108I6E Sulfatase AB285_05680 ENOG4105KST dependent repressor AB285_05685 ENOG4105F4P )-transporter AB285_05690 ENOG4105CW7 secretion protein, HlyD family AB285_05695 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB285_05705 ENOG4105CPC Aldo Keto reductase AB285_05710 ENOG4107RNH Outer membrane receptor FepA AB285_05715 ENOG4105NIV Esterase AB285_05720 ENOG4105E93 esterase AB285_05735 ENOG4105DJY efflux transporter, rnd family, mfp subunit AB285_05750 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AB285_05755 ENOG4105CS2 ec 3.2.1.21 AB285_05760 ENOG4105CK1 PTS System AB285_05765 ENOG4105FDP GntR family transcriptional regulator AB285_05770 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB285_05775 ENOG4105C5H ABC transporter AB285_05785 ENOG4105DPW Major facilitator superfamily MFS_1 AB285_05790 ENOG4105ETE Transcriptional regulator (LacI family AB285_05795 ENOG41072TH Protein of unknown function (DUF1479) AB285_05800 ENOG4108HCJ Hydrolase AB285_05805 ENOG4105C6N Formate acetyltransferase AB285_05810 ENOG4105F1A Pyruvate formate-lyase AB285_05815 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AB285_05820 ENOG4105D06 uba thif-type nad fad binding protein AB285_05825 ENOG4105CVM Molybdenum cofactor synthesis domain protein AB285_05830 ENOG4105D44 asparaginase AB285_05835 ENOG4108JQ6 ABC transporter AB285_05850 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB285_05855 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) AB285_05865 ENOG4105D8V Glucose sorbosone dehydrogenase AB285_05870 ENOG4108TGY Glutathione S-transferase AB285_05875 ENOG4105DZ1 carboxypeptidase AB285_05880 ENOG4107FB0 transcriptional regulator DeoR family AB285_05885 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AB285_05895 ENOG4107QF7 multi-drug AB285_05900 ENOG4108HCJ Hydrolase AB285_05905 ENOG4106UW1 Major Facilitator superfamily AB285_05910 ENOG4108RFG Tetr family transcriptional regulator AB285_05925 ENOG4105KBH arsR family transcriptional regulator AB285_05945 ENOG4105GWF inner membrane protein YbjM AB285_05950 ENOG41090BQ Glutaredoxin AB285_05955 ENOG4108DBC nitroreductase AB285_05960 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) AB285_05965 ENOG4108RMJ sensory transduction regulator AB285_05970 ENOG4107RUE extracellular solute-binding protein family 1 AB285_05975 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB285_05980 ENOG4105F38 ABC transporter, permease AB285_05985 ENOG4105D38 putrescine abc transporter AB285_05990 ENOG4105RBQ inner membrane protein ybjO AB285_05995 ENOG4107SFS Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity) AB285_06005 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB285_06010 ENOG4105BZU Histidine kinase AB285_06015 ENOG4106TNF Periplasmic binding protein AB285_06020 ENOG4105DMR ABC, transporter AB285_06025 ENOG4105GBT ABC transporter AB285_06030 ENOG4106PMH Extracellular solute-binding protein family 3 AB285_06035 ENOG4105E5Z arginine transporter ATP-binding subunit AB285_06040 ENOG41064MM (LipO)protein AB285_06045 ENOG4105K8R UPF0145 protein AB285_06050 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AB285_06055 ENOG4108PNB DNA-binding transcriptional regulator AB285_06070 ENOG4108XKW General secretion pathway protein C AB285_06075 ENOG4105GVR general secretion pathway protein D AB285_06080 ENOG4107QHF type ii secretion system protein e AB285_06085 ENOG4105D7Q type ii secretion system AB285_06090 ENOG4108VAU general secretion pathway protein G AB285_06100 ENOG4105X5Z General secretion pathway protein I AB285_06145 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AB285_06150 ENOG4105CGD Nad-dependent epimerase dehydratase AB285_06155 ENOG4105C5W Aldolase AB285_06160 ENOG4105C7K acetolactate synthase AB285_06170 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB285_06175 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) AB285_06180 ENOG4105DWU Membrane AB285_06185 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AB285_06190 ENOG4105CPB ATP-dependent endonuclease of the OLD family AB285_06195 ENOG4108MJ5 VirK protein AB285_06200 ENOG4105DJY efflux transporter, rnd family, mfp subunit AB285_06210 ENOG4105VEQ Cold shock protein AB285_06215 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) AB285_06220 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB285_06225 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) AB285_06230 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) AB285_06235 ENOG4108JJ8 (ABC) transporter AB285_06240 ENOG4108JJ9 ABC, transporter AB285_06245 ENOG4105C3M thioredoxin reductase AB285_06250 ENOG4105EW9 transcriptional regulator AsnC family AB285_06255 ENOG4105CNU cell division protein FtsK AB285_06260 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) AB285_06265 ENOG4105D1H recombination factor protein RarA AB285_06270 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) AB285_06275 ENOG4107QY8 reductase AB285_06280 ENOG4105QAX Iron-sulfur AB285_06285 ENOG4107KGK dmso reductase anchor subunit AB285_06290 ENOG4108ISG Major Facilitator AB285_06300 ENOG4105F1A Pyruvate formate-lyase AB285_06305 ENOG4105C6N Formate acetyltransferase AB285_06310 ENOG4105TMB Formate nitrite transporter AB285_06315 ENOG4105DDY UPF0142 protein ycaO AB285_06320 ENOG4107VMU Membrane AB285_06325 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) AB285_06330 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase AB285_06335 ENOG4105CAT Cytidine monophosphate kinase AB285_06340 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AB285_06345 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AB285_06350 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 AB285_06355 ENOG4105BZ1 (ABC) transporter AB285_06360 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) AB285_06365 ENOG4105T0Z Conserved Protein AB285_06370 ENOG4105W49 UPF0434 protein AB285_06375 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) AB285_06380 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups AB285_06385 ENOG4107S90 membrAne AB285_06390 ENOG4106371 Methyltransferase AB285_06395 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) AB285_06400 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) AB285_06405 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) AB285_06410 ENOG4105DIT ErfK YbiS YcfS YnhG family protein AB285_06415 ENOG4105EAQ (twin-arginine translocation) pathway signal AB285_06420 ENOG4105C5X domain protein AB285_06425 ENOG4105CGF Aromatic amino acid aminotransferase AB285_06435 ENOG4105C5S asparaginyl-tRNA synthetase AB285_06440 ENOG4107RH7 Nicotinate phosphoribosyltransferase AB285_06445 ENOG4105CD8 aminopeptidase N AB285_06455 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AB285_06460 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB285_06465 ENOG4105GVF (ABC) transporter AB285_06470 ENOG4108UZX fmn reductase AB285_06475 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) AB285_06480 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) AB285_06485 ENOG4105QVC MOSC domain-containing protein AB285_06490 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) AB285_06495 ENOG4105C5H ABC transporter AB285_06500 ENOG4105F1S paraquat-inducible protein a AB285_06505 ENOG4105DY2 Paraquat-inducible protein b AB285_06510 ENOG4108Q2G (LipO)protein AB285_06515 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) AB285_06525 ENOG4105DAN ATP-dependent protease AB285_06530 ENOG4108R9Q Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity) AB285_06535 ENOG4105UYK outer membrane protein a AB285_06540 ENOG4108ZD2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity) AB285_06545 ENOG4108RZ1 DNA transformation protein AB285_06550 ENOG4105EM2 membrane AB285_06555 ENOG410901E Membrane AB285_06560 ENOG41088T4 Helicase IV AB285_06565 ENOG4108Z5K methylglyoxal synthase AB285_06570 ENOG4108Q67 UPF0319 protein AB285_06575 ENOG4105K4P CoA-binding domain protein AB285_06580 ENOG4105GSS Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity) AB285_06585 ENOG4105DR4 Methyltransferase AB285_06590 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 AB285_06600 ENOG4108MN8 Membrane AB285_06605 ENOG4107QSI ABC, transporter AB285_06615 ENOG4105E0A ABC, transporter AB285_06620 ENOG4105EHG Permease protein AB285_06630 ENOG4105EGS Mechanosensitive ion channel AB285_06645 ENOG4105CJW magnesium transporter AB285_06650 ENOG4107T5V SNARE associated Golgi AB285_06655 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr AB285_06660 ENOG4105KVH Transcriptional regulator AB285_06670 ENOG4105D6F Phosphatase AB285_06675 ENOG4105XH3 AB285_06680 ENOG4105CS1 NAD(P)H quinone oxidoreductase AB285_06685 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 AB285_06695 ENOG4105C2W permease AB285_06700 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) AB285_06705 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) AB285_06710 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) AB285_06715 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) AB285_06720 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AB285_06725 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) AB285_06730 ENOG4108R86 Transcriptional regulator AB285_06740 ENOG4105C26 Dehydrogenase AB285_06745 ENOG4105CK7 Sodium proline symporter AB285_06755 ENOG4105D9N nucleoside AB285_06760 ENOG4105EKT )-iron permease AB285_06765 ENOG410650H (LipO)protein AB285_06770 ENOG4105DBE peroxidase AB285_06775 ENOG4105D5M phosphate starvation-inducible protein AB285_06780 ENOG4105BZG amino acid carrier protein AB285_06790 ENOG4105CHJ isochorismatase hydrolase AB285_06795 ENOG4105EUB pirin domain protein AB285_06800 ENOG4105CR8 Transcriptional regulator AB285_06810 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase AB285_06815 ENOG4107SSZ Phosphatase AB285_06820 ENOG4107XHZ cytoplasmic chaperone TorD family protein AB285_06825 ENOG4108UQ5 membrane protein YcdZ AB285_06830 ENOG4105P8Q Curli production assembly transport component CsgG AB285_06835 ENOG4108WYR Curli production assembly transport component, CsgF AB285_06840 ENOG4108XDW curli assembly protein CsgE AB285_06845 ENOG41086KC Transcriptional regulator AB285_06850 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers AB285_06870 ENOG4108UVJ appr-1-p processing domain protein AB285_06885 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) AB285_06890 ENOG4105NAC (LipO)protein AB285_06895 ENOG4108W47 Acidic protein msyB AB285_06900 ENOG4105C6X Major Facilitator AB285_06905 ENOG4105D1S lipid A biosynthesis AB285_06910 ENOG4105C72 UPF0176 protein AB285_06915 ENOG4108YYC ycei family AB285_06920 ENOG4105DS1 cytochrome b561 AB285_06925 ENOG4106974 biofilm formation AB285_06930 ENOG4105F76 Sarcosine oxidase AB285_06935 ENOG4105PVA Biofilm formation regulatory protein BssS AB285_06940 ENOG4105MEA DNA damage-inducible protein i AB285_06945 ENOG4105EKE dihydroorotase AB285_06950 ENOG4105F3T (LipO)protein AB285_06955 ENOG4105EV4 Multidrug resistance protein mdtH AB285_06960 ENOG4105D9U N-acetyltransferase AB285_06965 ENOG4108YXG UPF0502 protein AB285_06970 ENOG4105EP9 oxidoreductase AB285_06975 ENOG4105CJR Integral membrane protein (MviN AB285_06980 ENOG4105QVD Flagella synthesis protein FlgN AB285_06985 ENOG4105M9M anti-sigma28 factor FlgM AB285_06990 ENOG4105CKS Flagella basal body P-ring formation protein flgA AB285_06995 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AB285_07000 ENOG4108ZC9 flagellar basal-body rod protein flgc AB285_07005 ENOG4105W00 Flagellar hook capping protein AB285_07010 ENOG4105BZE flagellar hook protein, FlgE AB285_07015 ENOG4108KPB Flagellar basal-body rod protein FlgF AB285_07020 ENOG4105CGA flagellar basal-body rod protein FlgG AB285_07035 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj AB285_07040 ENOG4105E1Q flagellar hook-associated protein AB285_07045 ENOG4105DTJ flagellar hook-associated protein AB285_07050 ENOG4105EQ0 Major Facilitator superfamily AB285_07055 ENOG4105EJC lysr family transcriptional regulator AB285_07060 ENOG4107QQB Ribonuclease E AB285_07065 ENOG4105EI2 Pseudouridine synthase AB285_07075 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein AB285_07080 ENOG4105VGS 50s ribosomal protein l32 AB285_07085 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) AB285_07090 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AB285_07095 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AB285_07100 ENOG4105CHR reductase AB285_07105 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AB285_07110 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB285_07115 ENOG4105YAZ 4-amino-4-deoxychorismate lyase AB285_07120 ENOG4105HHA aminodeoxychorismate lyase AB285_07130 ENOG4107QRG dna polymerase iii AB285_07135 ENOG4105F8V Hydrolase, tatD family AB285_07140 ENOG4105CI1 PTS System AB285_07145 ENOG4105CNM Receptor AB285_07150 ENOG4105K59 histidine triad (HIT) protein AB285_07155 ENOG41090DQ Lipoprotein AB285_07160 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) AB285_07175 ENOG4105D0Y UPF0227 protein AB285_07180 ENOG4105CEP NADH dehydrogenase AB285_07185 ENOG4107MBR 17 kDa surface antigen AB285_07190 ENOG4108IND Tetr family transcriptional regulator AB285_07195 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AB285_07200 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB285_07205 ENOG4108JA2 transcriptioN-repair coupling factor AB285_07210 ENOG4105IQC Inner membrane protein YcfT AB285_07215 ENOG4105D60 lipoprotein releasing system transmembrane protein AB285_07220 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) AB285_07225 ENOG4105D60 lipoprotein releasing system transmembrane protein AB285_07230 ENOG4105EZX Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity) AB285_07235 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AB285_07240 ENOG4107RUE extracellular solute-binding protein family 1 AB285_07245 ENOG4108EG7 Binding-protein-dependent transport systems, inner membrane component AB285_07250 ENOG4105F38 ABC transporter, permease AB285_07265 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AB285_07270 ENOG4108UK5 Transposase AB285_07275 ENOG4105EZE Cupin 4 family protein AB285_07280 ENOG4105IFJ Histidine kinase AB285_07285 ENOG4105XJC Two component transcriptional regulator (Winged helix family AB285_07295 ENOG4107QTF adenylosuccinate lyase AB285_07300 ENOG41075W9 High frequency lysogenization protein HflD homolog AB285_07315 ENOG4108R99 pseudouridine synthase AB285_07320 ENOG4108HMX isocitrate dehydrogenase (NADP) AB285_07325 ENOG4105N0E Protein of unknown function (DUF2543) AB285_07330 ENOG41066DG (EAL) domain protein AB285_07335 ENOG4105Y3U Transglycosylase-associated protein AB285_07340 ENOG4106G4W AB285_07345 ENOG410620I Diguanylate cyclase AB285_07350 ENOG4105UCG Domain of unknown function (DUF333) AB285_07360 ENOG4105K78 MarR family Transcriptional regulator AB285_07365 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) AB285_07370 ENOG4105DJ2 Major Facilitator Superfamily AB285_07375 ENOG4105R1U AraC Family Transcriptional Regulator AB285_07380 ENOG4108VMM UPF0756 membrane protein AB285_07390 ENOG4105CT4 transporter AB285_07395 ENOG4108KXH Ybak prolyl-tRNA synthetase associated AB285_07400 ENOG4108I1J Integrase AB285_07450 ENOG4108S1U AB285_07460 ENOG4105CAR Terminase, large subunit AB285_07490 ENOG4108MXB Protein of unknown function (DUF968) AB285_07495 ENOG4105HRS Antitermination protein AB285_07555 ENOG4105CAR Terminase, large subunit AB285_07565 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AB285_07670 ENOG4106AKX UPF0229 protein AB285_07675 ENOG4105CYN Serine protein kinase AB285_07680 ENOG4105GNX MltA-interacting MipA family protein AB285_07685 ENOG4105DSB aldose 1-epimerase AB285_07690 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AB285_07700 ENOG4105VUT cytoplasmic protein AB285_07710 ENOG4108RWI nicotinamidase AB285_07715 ENOG4105HDK L-asparaginase AB285_07720 ENOG4105D07 Signal peptide peptidase, SppA AB285_07725 ENOG41069NU Nitroreductase AB285_07730 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) AB285_07735 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AB285_07740 ENOG4105D82 Glutamate dehydrogenase AB285_07745 ENOG4105MTM Protein of unknown function (DUF1496) AB285_07750 ENOG4105M6F mutator MutT protein AB285_07755 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AB285_07760 ENOG4108T9J Cdp-alcohol phosphatidyltransferase AB285_07765 ENOG4107RM6 sulfurtransferase AB285_07770 ENOG4108VGW abc transporter atp-binding protein AB285_07775 ENOG4105CXZ ABC transporter, permease AB285_07780 ENOG4105VNH ABC transporter solute-binding protein AB285_07790 ENOG4105CGK Exodeoxyribonuclease III AB285_07795 ENOG4105C8Y Acetylornithine aminotransferase AB285_07800 ENOG4105F4X arginine AB285_07805 ENOG4105C26 Dehydrogenase AB285_07810 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) AB285_07820 ENOG4108SPG Periplasmic Protein AB285_07825 ENOG41090B9 response to stress AB285_07830 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) AB285_07840 ENOG4105KKI DNA-binding transcriptional activator OsmE AB285_07845 ENOG4105VZJ PTS System AB285_07850 ENOG4105CK1 PTS System AB285_07855 ENOG4105VCP PTS System AB285_07860 ENOG4105EZV Transcriptional regulator AB285_07865 ENOG4105F8D glycoside hydrolase family 4 AB285_07870 ENOG410901P UPF0249 protein AB285_07875 ENOG4105CH6 catalase AB285_07885 ENOG4108ETY sodium dicarboxylate symporter AB285_07890 ENOG4107K5X Membrane-bound metal-dependent hydrolase AB285_07895 ENOG4105CHR reductase AB285_07900 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 AB285_07905 ENOG4107PN8 YfeABCD locus regulator AB285_07910 ENOG4105FGM Fructosamine kinase AB285_07915 ENOG4105P10 Uncharacterized protein ydiZ AB285_07920 ENOG4105DE4 1-phosphofructokinase AB285_07925 ENOG4108NE3 Salt-induced outer membrane protein AB285_07930 ENOG4105VR4 UPF0379 protein ybiJ AB285_07940 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) AB285_07945 ENOG41082NX 50s ribosomal protein l35 AB285_07950 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) AB285_07955 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) AB285_07960 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AB285_07965 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AB285_07975 ENOG4108V06 Glutathione peroxidase AB285_07980 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) AB285_07985 ENOG4108QBX (LipO)protein AB285_07990 ENOG4108TC0 Diguanylate phosphodiesterase AB285_07995 ENOG4105CNG UPF0061 protein AB285_08000 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) AB285_08005 ENOG4105EHG Permease protein AB285_08010 ENOG4107R4I Periplasmic binding protein AB285_08015 ENOG4106QJH hemin transport protein AB285_08020 ENOG4107ENK receptor AB285_08025 ENOG4106EDX Hemin uptake protein AB285_08030 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB285_08035 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) AB285_08040 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) AB285_08045 ENOG4105CT4 transporter AB285_08050 ENOG4107QK4 glycoside hydrolase, family 3 domain protein AB285_08055 ENOG4105IPI Membrane AB285_08060 ENOG4105CQB FAD linked oxidase domain protein AB285_08065 ENOG4105KA0 thioesterase Superfamily protein AB285_08070 ENOG410671Z uncharacterized protein ydiH AB285_08075 ENOG4108PNB DNA-binding transcriptional regulator AB285_08080 ENOG4108PNB DNA-binding transcriptional regulator AB285_08090 ENOG4108VCD Chaperone AB285_08095 ENOG4105CW0 outer membrane usher protein AB285_08115 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB285_08130 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component AB285_08135 ENOG4105BZU Histidine kinase AB285_08140 ENOG4108XDN Transcriptional regulator AB285_08145 ENOG4108Z4V iron-sulfur cluster assembly AB285_08150 ENOG4105DIW FeS assembly protein SUFB AB285_08155 ENOG4105C3K feS assembly ATPase SufC AB285_08160 ENOG4105JRK feS assembly protein SufD AB285_08165 ENOG4105C9B Cysteine desulfurase AB285_08170 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) AB285_08175 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB285_08185 ENOG4105CA9 Pyruvate kinase AB285_08190 ENOG4105C28 cystathionine AB285_08205 ENOG4108UMI ABC transporter, permease AB285_08210 ENOG4105D01 (LipO)protein AB285_08215 ENOG4105RFR Protein of unknown function (DUF2767) AB285_08220 ENOG4105DRP amino acid AbC transporter AB285_08225 ENOG4105E5Q amino acid AbC transporter AB285_08235 ENOG4106TNF Periplasmic binding protein AB285_08260 ENOG4107B2H carbonic anhydrase AB285_08265 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain AB285_08275 ENOG4108ZNX Heat shock protein AB285_08295 ENOG4108R6K riboflavin synthase, subunit alpha AB285_08300 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AB285_08305 ENOG4105CZQ inner membrane transport protein YdhC AB285_08310 ENOG4105F52 Transcriptional regulator AB285_08315 ENOG4105ETE Transcriptional regulator (LacI family AB285_08325 ENOG4105F27 Major Facilitator AB285_08330 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB285_08335 ENOG4105K4H Nlp p60 protein AB285_08340 ENOG4105M2J Glutaredoxin AB285_08345 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) AB285_08350 ENOG4108UYE Lactoylglutathione lyase AB285_08355 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB285_08360 ENOG4108WUH Transcriptional regulator, TetR family AB285_08365 ENOG4105DIJ Phosphoethanolamine transferase AB285_08370 ENOG4105XZD Fe-S protein AB285_08375 ENOG4107RGM aldo keto reductase AB285_08380 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB285_08385 ENOG4105DSW Fusaric acid resistance protein AB285_08390 ENOG4105Y49 secretion protein, HlyD family AB285_08405 ENOG4105BZU Histidine kinase AB285_08410 ENOG4108XTF Outer Membrane Lipoprotein AB285_08415 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) AB285_08420 ENOG410642K Lysozyme inhibitor AB285_08425 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) AB285_08430 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AB285_08435 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) AB285_08440 ENOG4108K3A Glutathione S-transferase AB285_08450 ENOG4105CSM endonuclease III AB285_08460 ENOG4108UQQ Electron transport complex AB285_08465 ENOG4105D6A Electron transport complex AB285_08480 ENOG4105DGN Electron transport complex AB285_08485 ENOG4105M9B inner membrane protein ydgK AB285_08495 ENOG4106C6R beta-lactam resistance protein AB285_08500 ENOG4105D9R oxidoreductase AB285_08505 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) AB285_08510 ENOG4105C87 Aminotransferase class I and II AB285_08515 ENOG4105CI1 PTS System AB285_08520 ENOG4107P2S Transcriptional regulator AB285_08525 ENOG4106J39 exported protein AB285_08530 ENOG4105EIP mannose-6-phosphate isomerase AB285_08535 ENOG4107GFK fumarate AB285_08540 ENOG4105C9Q fumarate hydratase class II AB285_08545 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) AB285_08550 ENOG4105JJR Histidine kinase AB285_08560 ENOG4105VEQ Cold shock protein AB285_08565 ENOG41066T8 Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation (By similarity) AB285_08570 ENOG4107EXC regulatoR AB285_08575 ENOG4105RA2 Membrane AB285_08580 ENOG410642E Short chain dehydrogenase AB285_08585 ENOG4105D5Q Arginine ornithine antiporter AB285_08590 ENOG4105C5D exported protein AB285_08595 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB285_08600 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB285_08605 ENOG4105D64 Mechanosensitive ion channel AB285_08610 ENOG4105Q9Y Universal stress protein AB285_08620 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AB285_08625 ENOG4105CFC Transporter AB285_08630 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B AB285_08640 ENOG4106KR7 LysR family Transcriptional regulator AB285_08645 ENOG4108DG9 Smr protein MutS2 AB285_08650 ENOG4105C8Q Methyl-accepting chemotaxis AB285_08655 ENOG4107S5I aldo keto reductase AB285_08665 ENOG4105KT5 UmuD protein AB285_08670 ENOG4105DZG Dehydrogenase AB285_08675 ENOG4107VK2 coenzyme PQQ biosynthesis protein PqqF AB285_08695 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) AB285_08700 ENOG4108IGT Dipeptidase AB285_08705 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AB285_08715 ENOG4105N1F Hnh endonuclease AB285_08725 ENOG4108M8W Monooxygenase AB285_08735 ENOG4105DSF transport protein AB285_08740 ENOG41090TI Catalyzes the excretion of spermidine (By similarity) AB285_08745 ENOG4108ZBZ Catalyzes the excretion of spermidine (By similarity) AB285_08750 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap AB285_08760 ENOG4105CTD carboxy-peptidase AB285_08765 ENOG4105D94 Major Facilitator Superfamily AB285_08770 ENOG4106NZI LysR family Transcriptional regulator AB285_08775 ENOG4105DAG ROK family AB285_08780 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) AB285_08785 ENOG4105CMQ Chloride channel AB285_08790 ENOG4108IJ8 ABC transporter AB285_08795 ENOG4105E90 ABC transporter AB285_08800 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system AB285_08805 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component AB285_08815 ENOG4107RTG Major Facilitator superfamily AB285_08820 ENOG4105ENX hydrolase AB285_08825 ENOG4105EQ2 LysR family Transcriptional regulator AB285_08830 ENOG4108UY2 Chloramphenicol acetyltransferase AB285_08840 ENOG4105X2V dna damage-inducible protein AB285_08845 ENOG4108NEM leader-binding protein dmsD AB285_08850 ENOG4107KGK dmso reductase anchor subunit AB285_08855 ENOG4105QAX Iron-sulfur AB285_08865 ENOG4105KBG Protein of unknown function (DUF1161) AB285_08880 ENOG4108MK9 spermidine N(1)-acetyltransferase AB285_08885 ENOG4105M5Q UPF0482 protein AB285_08890 ENOG4105KK4 UPF0060 membrane protein AB285_08895 ENOG4105CXK mandelate racemase muconate lactonizing AB285_08900 ENOG4105CPQ Dehydrogenase AB285_08910 ENOG4105D2H Uronic isomerase AB285_08920 ENOG4105DEI Mannitol dehydrogenase AB285_08925 ENOG41061EV selenium-binding protein YdfZ AB285_08930 ENOG4108U51 Universal stress protein AB285_08935 ENOG4107XBN GntR Family Transcriptional Regulator AB285_08940 ENOG4105EMU Dehydrogenase AB285_08945 ENOG4105DGW oligopeptidase A AB285_08955 ENOG4105CNM Receptor AB285_08965 ENOG41066FR extracellular solute-binding protein AB285_08970 ENOG4105D81 ABC transporter, permease AB285_08975 ENOG4105Y50 Virulence Protein AB285_08980 ENOG4105C44 Serine transporter AB285_08990 ENOG4105DZG Dehydrogenase AB285_09005 ENOG4105C5I Dehydrogenase AB285_09010 ENOG4107H52 Dicarboxylate transport AB285_09015 ENOG410689M (LipO)protein AB285_09020 ENOG4105WXT Conserved Protein AB285_09025 ENOG4108WFR AraC Family Transcriptional Regulator AB285_09030 ENOG4105C26 Dehydrogenase AB285_09040 ENOG4105EUZ Beta-lactamase domain protein AB285_09045 ENOG4105F11 amine oxidase AB285_09065 ENOG4105DXM phenylacetic acid degradation protein AB285_09070 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit AB285_09075 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit AB285_09080 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit AB285_09085 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit AB285_09090 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB285_09095 ENOG4105E39 Enoyl-CoA hydratase AB285_09100 ENOG4108UKI Enoyl-CoA hydratase AB285_09105 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB285_09110 ENOG4108ZJI phenylacetic acid degradation protein AB285_09115 ENOG4105CHU acetyl-coa acetyltransferase AB285_09120 ENOG4105DZS Phenylacetate-CoA ligase AB285_09125 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein AB285_09130 ENOG4108Z0R Transferase AB285_09140 ENOG4105EUZ Beta-lactamase domain protein AB285_09160 ENOG4107FW0 short-chain dehydrogenase reductase AB285_09175 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AB285_09205 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) AB285_09215 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme AB285_09220 ENOG4105D3G Pseudouridine synthase AB285_09225 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AB285_09230 ENOG4105CQ7 ATP-dependent helicase AB285_09235 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AB285_09250 ENOG4107DB1 DUF218 domain AB285_09255 ENOG4105C26 Dehydrogenase AB285_09260 ENOG4105CPW cytochrome b561 AB285_09265 ENOG4105D9R oxidoreductase AB285_09270 ENOG4105E98 transcriptional regulator DeoR family AB285_09285 ENOG4108JJA ABC, transporter AB285_09290 ENOG4105C42 Type I secretion membrane fusion protein (HlyD AB285_09315 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component AB285_09345 ENOG4105C8Q Methyl-accepting chemotaxis AB285_09350 ENOG4105DDW LysR family Transcriptional regulator AB285_09355 ENOG4105E32 cytoplasmic protein AB285_09360 ENOG4105EBR Carboxylesterase AB285_09370 ENOG4105CHM Aminotransferase AB285_09375 ENOG4105E89 ABC transporter AB285_09380 ENOG4105DJ9 glucan biosynthesis protein AB285_09385 ENOG4108Z9I -acetyltransferase AB285_09390 ENOG4107WE3 acetyltransferase YdcK AB285_09395 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein AB285_09400 ENOG41088CC tellurite resistance protein tehB AB285_09405 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AB285_09410 ENOG4105DEF Extracellular solute-binding protein, family 5 AB285_09415 ENOG4108KKZ (LipO)protein AB285_09430 ENOG4105DKK Benzoate AB285_09435 ENOG4108JCI Transcriptional regulator AB285_09440 ENOG4105CFP Peptidase U32 AB285_09445 ENOG4105RR0 Protein of unknown function (DUF2554) AB285_09455 ENOG4105ECQ AraC Family Transcriptional Regulator AB285_09475 ENOG4105C32 Amino acid ABC transporter (Permease) AB285_09480 ENOG4105CNN ABC, transporter AB285_09485 ENOG4108JJB ABC transporter AB285_09490 ENOG4108IV0 ABC, transporter AB285_09495 ENOG4108MEK Metal-binding protein YodA AB285_09500 ENOG4105E5W Transporter AB285_09505 ENOG4108594 Permease of the drug metabolite transporter AB285_09510 ENOG4106DNR multiple antibiotic resistance protein AB285_09520 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes AB285_09525 ENOG41082NP Multiple antibiotic resistance AB285_09535 ENOG4105F27 Major Facilitator AB285_09540 ENOG4105JAB phenazine biosynthesis protein, phzf family AB285_09545 ENOG4105JAB phenazine biosynthesis protein, phzf family AB285_09550 ENOG4105EGI Transcriptional regulator AB285_09555 ENOG4105C26 Dehydrogenase AB285_09560 ENOG4105C8Q Methyl-accepting chemotaxis AB285_09565 ENOG4105CSV Glutaminase AB285_09570 ENOG4105M0C cytoplasmic protein AB285_09575 ENOG4105BZU Histidine kinase AB285_09585 ENOG4107QZW Altronate oxidoreductase AB285_09590 ENOG4105FFC UPF0187 protein AB285_09605 ENOG4108MBX Secretion Protein AB285_09620 ENOG4108J2P Alpha beta hydrolase fold AB285_09625 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AB285_09630 ENOG4105E0F Histidine kinase AB285_09645 ENOG4107VIJ nudix hydrolase AB285_09650 ENOG4105E98 transcriptional regulator DeoR family AB285_09670 ENOG4108I6A alcohol dehydrogenase AB285_09810 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB285_09845 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) AB285_09855 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB285_09860 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB285_09870 ENOG4106NZI LysR family Transcriptional regulator AB285_09880 ENOG4107RSM transcriptional regulator AB285_09885 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AB285_09890 ENOG4105VYA Uncharacterized conserved protein (DUF2132) AB285_09895 ENOG4105F32 YngK protein AB285_09900 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase AB285_09915 ENOG4105C8Q Methyl-accepting chemotaxis AB285_09920 ENOG4105WBN Transcriptional regulator (LacI family AB285_09935 ENOG4108M0B Sucrose porin AB285_09940 ENOG4105D7K pfkb domain protein AB285_09945 ENOG4105BZU Histidine kinase AB285_09955 ENOG4108PSC Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity) AB285_09960 ENOG4108UQS dipeptidase AB285_09965 ENOG4105DEF Extracellular solute-binding protein, family 5 AB285_09970 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB285_09975 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB285_09980 ENOG4105C3U ABC transporter AB285_09985 ENOG4107H6U ABC transporter AB285_09990 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr AB285_10000 ENOG4108Z9K Osmotically inducible protein AB285_10005 ENOG4105EXG Transcriptional regulator AB285_10020 ENOG4105TPS biofilm-dependent modulation protein AB285_10030 ENOG4107R1I NAD-dependent malic enzyme AB285_10035 ENOG4105C5H ABC transporter AB285_10040 ENOG4105DQ4 alcohol dehydrogenase AB285_10055 ENOG4105F27 Major Facilitator AB285_10065 ENOG4108MG3 formate dehydrogenase AB285_10070 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AB285_10075 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB285_10080 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB285_10090 ENOG4105FCK Membrane AB285_10105 ENOG4107QND Nitrite extrusion protein AB285_10110 ENOG4105CRU nitrate reductase, alpha subunit AB285_10115 ENOG4108IUE nitrate reductase beta subunit AB285_10120 ENOG4108NZN Respiratory nitrate reductase 2 delta chain AB285_10125 ENOG4105D0D Nitrate reductase 2, gamma subunit AB285_10130 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase AB285_10135 ENOG4108MEJ flavin reductase domain protein AB285_10145 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) AB285_10150 ENOG4105YVS arsR family transcriptional regulator AB285_10160 ENOG4105D1S lipid A biosynthesis AB285_10165 ENOG4105KZK Tautomerase pptA AB285_10170 ENOG4108N27 Glutathione S-transferase AB285_10180 ENOG4105CDA abc transporter atp-binding protein AB285_10195 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) AB285_10205 ENOG4105CH2 amidohydrolase AB285_10210 ENOG4105DEN Luciferase family AB285_10225 ENOG4105EQ2 LysR family Transcriptional regulator AB285_10230 ENOG4105C85 amino acid AB285_10235 ENOG4108NS2 receptor AB285_10240 ENOG4105CHB tonB-dependent Receptor AB285_10245 ENOG4108WYP Transcriptional regulator AB285_10250 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein AB285_10260 ENOG4108Z7F N-acetyltransferase AB285_10265 ENOG4108T9Y Inner membrane protein ydcZ AB285_10270 ENOG4105R71 cytoplasmic protein AB285_10275 ENOG4105DEF Extracellular solute-binding protein, family 5 AB285_10300 ENOG410654E Membrane AB285_10305 ENOG4108YS1 cytoplasmic protein AB285_10310 ENOG4108YS1 cytoplasmic protein AB285_10315 ENOG4105YP6 Domain of unknown function (DUF1869) AB285_10320 ENOG4105C26 Dehydrogenase AB285_10325 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB285_10335 ENOG4105C4M (Ubiquinol oxidase) subunit I AB285_10340 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB285_10350 ENOG41090X5 Heat shock protein hslJ AB285_10360 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) AB285_10365 ENOG4105FCK Membrane AB285_10380 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) AB285_10385 ENOG4105C1J atp-dependent rna helicase AB285_10390 ENOG4107RX3 Mg2 transporter protein cora family protein AB285_10395 ENOG4105C8Q Methyl-accepting chemotaxis AB285_10420 ENOG4107QSI ABC, transporter AB285_10425 ENOG4105KXI murein peptide amidase A AB285_10430 ENOG4107S8C mandelate racemase muconate lactonizing AB285_10435 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AB285_10440 ENOG4108JU8 Transcriptional regulator AB285_10445 ENOG4106K28 UPF0283 membrane protein AB285_10450 ENOG4105CM6 amino acid regulated cytosolic protein AB285_10455 ENOG4105FKQ transcriptional regulator AB285_10460 ENOG4107EFV Outer membrane protein G AB285_10465 ENOG4108IJ9 (ABC) transporter AB285_10470 ENOG4107URF beta-phospho-glucomutase AB285_10475 ENOG4105C71 hydrolase family 65, central catalytic AB285_10480 ENOG4105CK5 oxidoreductase AB285_10485 ENOG4107TYA transient receptor potential locus AB285_10490 ENOG4107RRD Dehydrogenase AB285_10495 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component AB285_10500 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component AB285_10505 ENOG4105WEM extracellular solute-binding protein AB285_10510 ENOG4107QW3 Sucrose phosphorylase AB285_10515 ENOG4105NNG Peripheral inner membrane phage-shock protein AB285_10520 ENOG4105FM1 phage shock protein C AB285_10525 ENOG4105YYT phage shock protein B AB285_10530 ENOG41087YS Phage shock protein A AB285_10535 ENOG4105E51 psp operon transcriptional activator AB285_10540 ENOG4108J59 Extracellular solute-binding protein, family 5 AB285_10545 ENOG4108I5W peptide transport system, permease protein AB285_10550 ENOG4108EU3 peptide transport system, permease AB285_10555 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein AB285_10560 ENOG4108JQ2 peptide transport system atp-binding protein AB285_10570 ENOG4108UQ8 endoribonuclease L-psp AB285_10580 ENOG4105BZU Histidine kinase AB285_10585 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH AB285_10590 ENOG4105Q4T oxidoreductase AB285_10595 ENOG4108IEC Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity) AB285_10600 ENOG4105BZU Histidine kinase AB285_10605 ENOG4105E39 Enoyl-CoA hydratase AB285_10610 ENOG410643D UPF0509 protein AB285_10615 ENOG4105N2W Transcriptional regulator AB285_10620 ENOG41061RM osmotically inducible lipoprotein AB285_10625 ENOG4108ZJT translation initiation factor, Sui1 AB285_10630 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) AB285_10635 ENOG4105CFV Tetratricopeptide repeat protein AB285_10640 ENOG4105Q4A inner membrane protein yciS AB285_10645 ENOG4105EYK Phosphatidylglycerophosphatase B AB285_10655 ENOG4107QM5 aconitate hydratase AB285_10675 ENOG4107R11 Transcriptional regulator AB285_10680 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AB285_10685 ENOG4105RKX Protein of unknown function (DUF2498) AB285_10690 ENOG4105ERU peptidase AB285_10695 ENOG4105UBK short-chain dehydrogenase reductase AB285_10700 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase AB285_10705 ENOG4105FE9 pseudouridine synthase AB285_10780 ENOG41090RK glycosyl transferase AB285_10785 ENOG4107RTD sua5 ycio yrdc ywlc family protein AB285_10790 ENOG4105DB7 PHP domain protein AB285_10795 ENOG4105CRQ synthase (Component I) AB285_10800 ENOG4108EFP Anthranilate synthase component II AB285_10805 ENOG4105DK0 Indole-3-glycerol phosphate synthase AB285_10810 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AB285_10815 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) AB285_10820 ENOG41066VF YeeE YedE family protein AB285_10825 ENOG4105KSU Redox protein AB285_10830 ENOG4105EIF outer membrane protein W AB285_10835 ENOG4105PI0 Ferredoxin AB285_10840 ENOG4108S3I UPF0259 membrane protein AB285_10845 ENOG4107835 probably involved in intracellular septation (By similarity) AB285_10850 ENOG4107RNH Outer membrane receptor FepA AB285_10855 ENOG4105NAU thioesterase Superfamily protein AB285_10860 ENOG410822N TonB family AB285_10865 ENOG4105K9H YciI-like protein AB285_10870 ENOG4108NIW Leucine export protein LeuE AB285_10880 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AB285_10885 ENOG4108W5H UPF0263 protein AB285_10890 ENOG4105EYW Ion transport protein AB285_10895 ENOG4108JQ7 (ABC) transporter AB285_10900 ENOG4105C3U ABC transporter AB285_10905 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB285_10915 ENOG4107QSI ABC, transporter AB285_10925 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein AB285_10930 ENOG4108EKI Dehydrogenase AB285_10935 ENOG4107104 thymidine kinase AB285_10945 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AB285_10950 ENOG4105I93 response regulator AB285_10955 ENOG4105D78 K07001 NTE family protein AB285_10960 ENOG4105K5B UPF0225 protein AB285_10965 ENOG4105CIY formyltetrahydrofolate deformylase AB285_10980 ENOG41076YT nitrate reductase, gamma subunit AB285_10985 ENOG4105R3A Nitrate reductase AB285_10990 ENOG4108IUE nitrate reductase beta subunit AB285_10995 ENOG4105CRU nitrate reductase, alpha subunit AB285_11000 ENOG4105DQQ Major facilitator superfamily MFS_1 AB285_11005 ENOG4105BZU Histidine kinase AB285_11010 ENOG4105WH1 Two component transcriptional regulator luxr family AB285_11015 ENOG4105ID0 Putative invasin AB285_11025 ENOG4107QZF nitrite reductase NADPH large subunit AB285_11030 ENOG4105D7T ABC transporter AB285_11050 ENOG41090EX DsrE family AB285_11055 ENOG4105C8Q Methyl-accepting chemotaxis AB285_11065 ENOG4108NH8 Cation transport protein AB285_11070 ENOG4105WS7 Cation transport regulator AB285_11075 ENOG4105EWV Sodium calcium exchanger membrane region AB285_11080 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase AB285_11090 ENOG4108YY7 Invasion gene expression up-regulator SirB AB285_11095 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AB285_11100 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) AB285_11105 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) AB285_11110 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) AB285_11115 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) AB285_11120 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AB285_11125 ENOG4105CHH sulfate transporter AB285_11135 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria AB285_11140 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) AB285_11145 ENOG4105C3G gtp-binding protein AB285_11155 ENOG4105CNA YD repeat protein AB285_11180 ENOG4105D9P serine threonine protein kinase AB285_11185 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB285_11235 ENOG4108WC9 type VI secretion system effector, hcp1 family AB285_11275 ENOG4106VK6 Flagellar motor protein AB285_11310 ENOG4105E53 ec 3.2.1.28 AB285_11315 ENOG4105E0K tonB-dependent siderophore receptor AB285_11320 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) AB285_11325 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division AB285_11330 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A AB285_11335 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) AB285_11340 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AB285_11345 ENOG4105MWK D-amino acid dehydrogenase, small subunit AB285_11355 ENOG4105ED1 spovr family AB285_11365 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AB285_11375 ENOG4108ZZ3 UPF0260 protein AB285_11380 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AB285_11390 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) AB285_11395 ENOG4107QMS site-determining protein AB285_11400 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) AB285_11405 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) AB285_11410 ENOG4105CEY Amp-dependent synthetase and ligase AB285_11415 ENOG4105Y4Z Outer Membrane Lipoprotein AB285_11420 ENOG41072GX Peptidase M22 Glycoprotease AB285_11425 ENOG4105DVT helicase AB285_11430 ENOG4105M4H endoribonuclease L-psp AB285_11435 ENOG4105X5C UPF0181 protein AB285_11440 ENOG4105CRQ synthase (Component I) AB285_11445 ENOG4105P8F nudix hydrolase AB285_11450 ENOG4105EJQ L-serine dehydratase AB285_11455 ENOG4107XTP (EAL) domain protein AB285_11460 ENOG4105EE5 Membrane protein terC AB285_11465 ENOG4108EQA pts system AB285_11470 ENOG4105ETZ PTS System AB285_11475 ENOG4105F3R pts system mannose fructose sorbose family iid AB285_11480 ENOG4108NK4 UPF0266 membrane protein AB285_11485 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) AB285_11490 ENOG4105DHI Methyltransferase AB285_11495 ENOG4105CJN penicillin-binding protein AB285_11500 ENOG4105VEQ Cold shock protein AB285_11505 ENOG410610J Protein of unknown function (DUF2627) AB285_11510 ENOG4105Q3Y exported protein AB285_11515 ENOG4106CCY Protein MgrB homolog AB285_11520 ENOG4105TIK AB285_11525 ENOG4105J4Q Transcriptional regulator AB285_11530 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB285_11535 ENOG4105D0M Protease HtpX homolog AB285_11540 ENOG4105CN1 protease AB285_11545 ENOG41073DY may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity) AB285_11550 ENOG4108ZGC gaf domain protein AB285_11555 ENOG4105H2K paraquat-inducible protein a AB285_11560 ENOG4105DY2 Paraquat-inducible protein b AB285_11565 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AB285_11570 ENOG4105WT8 Protein of unknown function (DUF1480) AB285_11575 ENOG4108R1E Serine threonine protein phosphatase 1 AB285_11580 ENOG4108MJ5 VirK protein AB285_11590 ENOG4105NKT exported protein AB285_11595 ENOG4108PNC copper resistance AB285_11600 ENOG4105FXM Copper resistance protein AB285_11605 ENOG4105MPK DNA polymerase III subunit theta AB285_11610 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AB285_11615 ENOG4105UMD exodeoxyribonuclease X AB285_11620 ENOG4105CUG Oligopeptidase b AB285_11625 ENOG4108Q2J Inner membrane protein YebE AB285_11635 ENOG4108UHU Aldolase AB285_11640 ENOG4105C01 Dihydroxy-acid dehydratase AB285_11645 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AB285_11650 ENOG4106KNT transcriptional regulator AB285_11655 ENOG4105CA9 Pyruvate kinase AB285_11660 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase AB285_11665 ENOG4105DR5 peptidase AB285_11670 ENOG4105NXV High-affinity zinc uptake system protein AB285_11680 ENOG4105FAV ABC, transporter AB285_11685 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) AB285_11690 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) AB285_11695 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) AB285_11700 ENOG4105CDY transcriptional regulatory protein AB285_11705 ENOG4108TIT dATP pyrophosphohydrolase AB285_11710 ENOG4105C9M aspartyl-trna synthetase AB285_11715 ENOG4105D3W isochorismatase AB285_11720 ENOG41081XQ Conserved Protein AB285_11725 ENOG4105WJG Glutathione AB285_11730 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) AB285_11735 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) AB285_11740 ENOG4106N3A copper homeostasis protein cutc AB285_11745 ENOG4106ZCM YecM protein AB285_11750 ENOG4105C75 arginyL-tRNA synthetase AB285_11755 ENOG4105F5H Glycosyl Hydrolase Family 88 AB285_11760 ENOG4105CT4 transporter AB285_11765 ENOG4105W13 flagellar protein AB285_11770 ENOG4105D7B Flagellar biosynthesis protein flha AB285_11775 ENOG4105D00 flagellar biosynthetic protein flhB AB285_11780 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) AB285_11785 ENOG4108VYJ response regulator receiver protein AB285_11795 ENOG4105BZU Histidine kinase AB285_11800 ENOG4105C8Q Methyl-accepting chemotaxis AB285_11805 ENOG4105C8Q Methyl-accepting chemotaxis AB285_11835 ENOG4107QJT sodium dicarboxylate symporter AB285_11840 ENOG4108V3W Chemotaxis protein, CheW AB285_11845 ENOG4105CBS Chea signal transduction histidine kinase AB285_11850 ENOG4105ER2 Ompa motb domain protein AB285_11855 ENOG4107RD7 Flagellar Motor Protein, MotA AB285_11860 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region AB285_11865 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) AB285_11870 ENOG4108VA4 Universal stress protein AB285_11875 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase AB285_11880 ENOG4108K4C ec 3.1.3.12 AB285_11885 ENOG4105CNN ABC, transporter AB285_11895 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator AB285_11905 ENOG4108UEC Ferritin-like protein AB285_11910 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AB285_11915 ENOG4105N4N Protein of unknown function (DUF2766) AB285_11935 ENOG41090A1 ferritin AB285_11940 ENOG4105VVZ metal-binding protein AB285_11945 ENOG4105E0U tyrosine-specific transport protein AB285_11950 ENOG4106RHG Yeca family AB285_11960 ENOG4105C32 Amino acid ABC transporter (Permease) AB285_11965 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AB285_11970 ENOG4105C0Z ABC transporter AB285_11975 ENOG4108IV0 ABC, transporter AB285_11985 ENOG4105DQS Transcriptional regulator AB285_12025 ENOG4105UZW Tail fiber assembly protein AB285_12030 ENOG410685N tail fiber protein AB285_12115 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AB285_12170 ENOG4105NVB glycoside hydrolase, family 19 AB285_12195 ENOG4105NI8 Cytosine-specific methyltransferase AB285_12235 ENOG4105JBR DNA replication protein AB285_12240 ENOG4105YQ0 AB285_12300 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AB285_12305 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) AB285_12310 ENOG4105WH1 Two component transcriptional regulator luxr family AB285_12315 ENOG4105XVG cytoplasmic protein AB285_12320 ENOG4105VJY transcriptional regulator AB285_12325 ENOG4105CDA abc transporter atp-binding protein AB285_12330 ENOG4105E5Q amino acid AbC transporter AB285_12340 ENOG4105EAB amino acid AbC transporter AB285_12345 ENOG4108M9K flagella biosynthesis protein FliZ AB285_12350 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB285_12360 ENOG4105DTS flagellar hook-associated AB285_12365 ENOG4105MQ3 flagellar protein FliS AB285_12375 ENOG4105E5K Alpha-amylase AB285_12380 ENOG4108W9D (LipO)protein AB285_12385 ENOG4105VQ0 flagellar hook-basal body complex protein fliE AB285_12390 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AB285_12395 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AB285_12400 ENOG41090PJ Flagellar assembly protein AB285_12405 ENOG4108JIR Flagellum-specific ATP synthase AB285_12410 ENOG4105GSA Flagellar export protein flij AB285_12415 ENOG4105WF4 Flagellar hook-length control protein AB285_12420 ENOG4107ZI8 flagellar basal body-associated protein flil AB285_12425 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AB285_12430 ENOG4105DD5 Flagellar motor switch protein AB285_12435 ENOG4105K0P flagellar biosynthesis protein AB285_12440 ENOG4105CN7 Flagellar biosynthetic protein FliP AB285_12445 ENOG4105VS8 Flagellar biosynthetic protein fliq AB285_12450 ENOG4105D19 Role in flagellar biosynthesis (By similarity) AB285_12455 ENOG4107TKS colanic acid capsular biosynthesis activation protein A AB285_12465 ENOG4105YX3 cellular response to acidity AB285_12480 ENOG4105VNZ cytoplasmic protein AB285_12485 ENOG4105CKW Inner membrane protein yedI AB285_12490 ENOG4105FDR Membrane AB285_12495 ENOG41090BB DNA mismatch endonuclease (vsr) AB285_12500 ENOG4105DVF Cytosine-specific methyltransferase AB285_12505 ENOG4105EST Metal Dependent Phosphohydrolase AB285_12510 ENOG4105FCK Membrane AB285_12515 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate AB285_12520 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AB285_12525 ENOG4108MRH transcriptional regulatory protein AB285_12545 ENOG4107GFK fumarate AB285_12560 ENOG4105CSH Transporter AB285_12570 ENOG4105F04 LysR family Transcriptional regulator AB285_12595 ENOG4105DUU IucA IucC family protein AB285_12600 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) AB285_12620 ENOG4105XUP Phage derived protein Gp49-like (DUF891) AB285_12625 ENOG4107R11 Transcriptional regulator AB285_12640 ENOG4108PXI ErfK YbiS YcfS YnhG AB285_12650 ENOG4108U51 Universal stress protein AB285_12660 ENOG4105BZS acriflavin resistance protein AB285_12675 ENOG4105CSH Transporter AB285_12680 ENOG4105FYV Amp nucleosidase AB285_12690 ENOG4105UQX Mate efflux family protein AB285_12705 ENOG4105DR8 Membrane AB285_12710 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) AB285_12715 ENOG4105DZ1 carboxypeptidase AB285_12720 ENOG4105CJB Exodeoxyribonuclease I AB285_12725 ENOG4105CUB amino acid AB285_12730 ENOG4105EQ1 Transcriptional regulator AB285_12735 ENOG4108535 NAD dependent epimerase/dehydratase family AB285_12740 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) AB285_12750 ENOG4105CIH Imidazole acetol-phosphate transaminase AB285_12760 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) AB285_12765 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase AB285_12770 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) AB285_12775 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AB285_12780 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) AB285_12795 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AB285_12800 ENOG4105C1B dTDP-glucose 4-6-dehydratase AB285_12805 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AB285_12810 ENOG4107QKV phosphomannomutase AB285_12815 ENOG4105CJT Mannose-1-phosphate guanylyltransferase AB285_12845 ENOG4105ER6 polysaccharide biosynthesis protein AB285_12850 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AB285_12855 ENOG4105G1A colanic acid biosynthesis protein AB285_12860 ENOG4107T8Q Glycosyl transferase (Group 1 AB285_12865 ENOG4105C74 pyruvyl transferase AB285_12870 ENOG4105PSV Polysaccharide Biosynthesis Protein AB285_12875 ENOG4105D3Q Sugar transferase AB285_12880 ENOG4107QKV phosphomannomutase AB285_12885 ENOG4105CJT Mannose-1-phosphate guanylyltransferase AB285_12890 ENOG4106CD9 glycosyl transferase group 1 AB285_12895 ENOG4105FGF GDP-mannose mannosyl hydrolase AB285_12900 ENOG4105C30 Nad-dependent epimerase dehydratase AB285_12905 ENOG4105C0K Gdp-mannose 4,6-dehydratase AB285_12910 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF AB285_12915 ENOG4105ECJ Glycosyl Transferase AB285_12920 ENOG4108NYJ Colanic acid AB285_12925 ENOG4107RXY Glycosyl transferase AB285_12930 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB AB285_12935 ENOG41090RK glycosyl transferase AB285_12940 ENOG4105D75 Capsular exopolysaccharide family AB285_12945 ENOG4105KJF protein tyrosine phosphatase AB285_12950 ENOG4105DAY polysaccharide export protein AB285_12955 ENOG4105EE5 Membrane protein terC AB285_12960 ENOG4108GAE asmA family AB285_12965 ENOG4105DHP deoxycytidine triphosphate deaminase AB285_12975 ENOG4105BZU Histidine kinase AB285_12980 ENOG4105D03 DNA-3-methyladenine glycosylase II AB285_12985 ENOG4105R8A Heat shock protein AB285_12990 ENOG4105ENT Efflux transporter rnd family, mfp subunit AB285_12995 ENOG4105BZS acriflavin resistance protein AB285_13000 ENOG4105BZS acriflavin resistance protein AB285_13005 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB285_13010 ENOG4105EB3 Histidine kinase AB285_13015 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB285_13025 ENOG4105CFP Peptidase U32 AB285_13030 ENOG4107TE5 Lipid kinase AB285_13035 ENOG4108JQ7 (ABC) transporter AB285_13050 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB285_13055 ENOG4105DEF Extracellular solute-binding protein, family 5 AB285_13060 ENOG4105CXK mandelate racemase muconate lactonizing AB285_13065 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 AB285_13070 ENOG4105IE8 Alpha-ketoglutarate permease AB285_13075 ENOG4105CMG Carbohydrate kinase AB285_13080 ENOG4105DEI Mannitol dehydrogenase AB285_13085 ENOG4105DKT Transcriptional regulator AB285_13100 ENOG4105CMG Carbohydrate kinase AB285_13105 ENOG4105IE8 Alpha-ketoglutarate permease AB285_13110 ENOG4105EIE fructose-bisphosphate aldolase AB285_13115 ENOG4105EAA nucleoside AB285_13120 ENOG4108KD5 ADP-ribosylation crystallin J1 AB285_13125 ENOG4108TFM Kinase, PfkB family AB285_13130 ENOG4105FDP GntR family transcriptional regulator AB285_13135 ENOG4105DWF phosphomethylpyrimidine kinase AB285_13140 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase AB285_13155 ENOG4108JPW Aminotransferase AB285_13160 ENOG4105DY8 decarboxylase AB285_13165 ENOG4108F2G Chain length determinant protein AB285_13170 ENOG4107ZF2 Phosphatase AB285_13175 ENOG4105DAY polysaccharide export protein AB285_13180 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly AB285_13190 ENOG4105D1F ATP-binding protein AB285_13200 ENOG4108W15 Protein of unknown function (DUF1456) AB285_13205 ENOG4108NEV two component transcriptional regulator, LytTR family AB285_13210 ENOG4108HRK Histidine kinase AB285_13215 ENOG4108XDN Transcriptional regulator AB285_13220 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component AB285_13225 ENOG4108IJ8 ABC transporter AB285_13230 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component AB285_13235 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system AB285_13240 ENOG4107QK4 glycoside hydrolase, family 3 domain protein AB285_13245 ENOG4105CXG d-lactate dehydrogenase AB285_13255 ENOG41061WM D-Alanyl-D-Alanine AB285_13260 ENOG41069YE inner membrane protein yohC AB285_13265 ENOG4105KHU inner membrane protein YohD AB285_13270 ENOG4105H9W Short-chain dehydrogenase reductase Sdr AB285_13275 ENOG4105ETP RND efflux system, outer membrane lipoprotein AB285_13280 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) AB285_13285 ENOG4105VAW lrga family AB285_13290 ENOG41067MG lrgb family AB285_13295 ENOG4107T42 This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity) AB285_13300 ENOG4107GZ4 SanA protein AB285_13305 ENOG4107SDZ Galactoside transport system permease protein mglC AB285_13310 ENOG4105C2J ABC transporter AB285_13320 ENOG41060NJ transcriptional regulator AB285_13325 ENOG4105DHF Membrane AB285_13330 ENOG4105EUJ GTP cyclohydrolase i AB285_13335 ENOG4105CBP Major Facilitator AB285_13340 ENOG4105C4W S-formylglutathione hydrolase AB285_13345 ENOG4105D05 Receptor AB285_13350 ENOG4108IQI permease AB285_13355 ENOG4105DUM transcriptional regulator, lysR family AB285_13360 ENOG4105HMI Membrane AB285_13365 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) AB285_13370 ENOG4105DM4 PTS System AB285_13375 ENOG4105DE4 1-phosphofructokinase AB285_13380 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein AB285_13385 ENOG4105S8Q sugar efflux transporter AB285_13390 ENOG4105KRS Proteinase inhibitor AB285_13395 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) AB285_13400 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) AB285_13405 ENOG4105DEI Mannitol dehydrogenase AB285_13410 ENOG4105CKI cobalamin synthesis protein AB285_13415 ENOG41076MN Phosphoesterase, PA-phosphatase related AB285_13420 ENOG4107TT5 NLP P60 protein AB285_13425 ENOG4105CXC rtn protein AB285_13430 ENOG4105E43 Extracellular solute-binding protein, family 5 AB285_13435 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component AB285_13440 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component AB285_13445 ENOG4108JQ5 ABC transporter AB285_13450 ENOG4105HG6 AB285_13455 ENOG4105C2C drug resistance transporter, Bcr CflA AB285_13460 ENOG4105I08 Pseudouridine synthase AB285_13465 ENOG4105CFI type iii restriction protein res subunit AB285_13470 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) AB285_13475 ENOG4106V8H Nucleoid-associated protein AB285_13480 ENOG4105PAN UPF0352 protein AB285_13485 ENOG4105E68 Sulfatase AB285_13495 ENOG4105S5I Membrane AB285_13500 ENOG4108QSZ General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity) AB285_13505 ENOG4105DWT malate dehydrogenase (quinone) AB285_13510 ENOG4105CHH sulfate transporter AB285_13515 ENOG4105CJW magnesium transporter AB285_13520 ENOG4105IBP Cyclic peptide transporter AB285_13525 ENOG4105CF1 Alkylated DNA repair protein AB285_13530 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AB285_13545 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC AB285_13550 ENOG41068CG regulatoR AB285_13555 ENOG4105BZU Histidine kinase AB285_13560 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB285_13565 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) AB285_13570 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB285_13575 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB285_13580 ENOG4105XPH Ferredoxin AB285_13585 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase AB285_13590 ENOG4105CXY transporter AB285_13595 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A AB285_13600 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B AB285_13605 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AB285_13615 ENOG4108UII YfaZ family AB285_13620 ENOG4105DHQ Histidine kinase AB285_13645 ENOG4105CEY Amp-dependent synthetase and ligase AB285_13650 ENOG4105DNI Converts SHCHC to OSB (By similarity) AB285_13655 ENOG4108IPT Naphthoate synthase AB285_13660 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) AB285_13665 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) AB285_13670 ENOG4105E4F Isochorismate synthase AB285_13675 ENOG4105TNS Conserved Protein AB285_13680 ENOG4107YB6 acetyltransferase, (GNAT) family AB285_13685 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AB285_13690 ENOG4107R88 Chemotaxis protein (CheV) AB285_13695 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB285_13700 ENOG4105C8S subunit m AB285_13705 ENOG4105D65 subunit l AB285_13710 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB285_13715 ENOG4107UFS subunit j AB285_13725 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) AB285_13730 ENOG4107R0R NADH dehydrogenase subunit g AB285_13735 ENOG4107QIZ NADH dehydrogenase AB285_13740 ENOG4105GKE subunit e AB285_13745 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB285_13755 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AB285_13760 ENOG4107NQ8 LysR family Transcriptional regulator AB285_13765 ENOG4105CHM Aminotransferase AB285_13770 ENOG4105DK2 UPF0207 protein AB285_13775 ENOG4107QWE )-transporter AB285_13780 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 AB285_13785 ENOG4105XWI UPF0304 protein AB285_13795 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AB285_13800 ENOG4105C6K Malic enzyme AB285_13805 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) AB285_13810 ENOG4108HHA Transketolase AB285_13815 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC AB285_13825 ENOG4106ETB IIa component AB285_13830 ENOG4105K2J Transcriptional regulator AB285_13835 ENOG4105PTV Nudix Hydrolase AB285_13840 ENOG4108RE9 Phosphodiesterase AB285_13845 ENOG4108SHQ Glutathione S-transferase AB285_13850 ENOG4105CYM Glutathione S-transferase AB285_13855 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase AB285_13860 ENOG4105ECP epimerase AB285_13865 ENOG4105D9U N-acetyltransferase AB285_13870 ENOG4108JEH abc transporter atp-binding protein AB285_13875 ENOG4106YG3 ABC transporter AB285_13880 ENOG4105DSP amino acid AbC transporter AB285_13885 ENOG4105E89 ABC transporter AB285_13890 ENOG4105E89 ABC transporter AB285_13895 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AB285_13900 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase AB285_13905 ENOG4105E96 Colicin v production protein AB285_13910 ENOG4108S3P Sporulation domain protein AB285_13915 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AB285_13920 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) AB285_13925 ENOG4105DQR SNARE associated Golgi AB285_13930 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AB285_13935 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AB285_13940 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) AB285_13945 ENOG4106WZ1 flagella biosynthesis regulator AB285_13950 ENOG4105F9N Major Facilitator Superfamily AB285_13955 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB285_13960 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) AB285_13965 ENOG4105MH2 YfcL protein AB285_13970 ENOG4108BPE -transporting atpase AB285_13975 ENOG4105EJ9 Membrane AB285_13980 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) AB285_13985 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase AB285_13990 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) AB285_13995 ENOG4108DG9 Smr protein MutS2 AB285_14000 ENOG4108BY2 phosphohistidine phosphatase AB285_14005 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB285_14010 ENOG4105CHU acetyl-coa acetyltransferase AB285_14015 ENOG4105KZW UPF0381 protein AB285_14020 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation AB285_14025 ENOG410903C (LipO)protein AB285_14030 ENOG4105S64 Formate nitrite transporter AB285_14040 ENOG4105BZU Histidine kinase AB285_14045 ENOG4105D1S lipid A biosynthesis AB285_14055 ENOG4105CHM Aminotransferase AB285_14060 ENOG4108HRK Histidine kinase AB285_14065 ENOG4105DY9 regulatoR AB285_14070 ENOG4105CHC glucokinase (EC 2.7.1.2) AB285_14075 ENOG4105VCT ion-transport protein YfeO AB285_14080 ENOG4107RA9 decarboxylase AB285_14085 ENOG4105CPC Aldo Keto reductase AB285_14095 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) AB285_14100 ENOG4105D9N nucleoside AB285_14105 ENOG4108KMM Diguanylate cyclase AB285_14120 ENOG4105HZG regulatoR AB285_14125 ENOG4105GXM Putative transcription regulator (DUF1323) AB285_14130 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) AB285_14165 ENOG4108M0I Transcriptional regulator AB285_14170 ENOG4105DHU Bile acid AB285_14175 ENOG4105VRT cytoplasmic protein AB285_14180 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) AB285_14185 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) AB285_14190 ENOG4105EXN Sulfate transport protein CysZ AB285_14195 ENOG4105C6T cysteine synthase AB285_14200 ENOG4105KZ7 phosphocarrier protein hpr AB285_14210 ENOG4105C5Y PTS System AB285_14220 ENOG4105C6T cysteine synthase AB285_14225 ENOG4108IJ6 ABC transporter AB285_14230 ENOG4105ECW sulfate abc transporter AB285_14235 ENOG4108I5D sulfate abc transporter AB285_14240 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein AB285_14245 ENOG4105EZR dyp-type peroxidase family protein AB285_14250 ENOG4105E7K (LipO)protein AB285_14255 ENOG4105QZU Inner membrane protein YfeZ AB285_14265 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase AB285_14270 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) AB285_14275 ENOG4105C6K Malic enzyme AB285_14285 ENOG4105CV1 Transketolase (EC 2.2.1.1) AB285_14290 ENOG4108Y51 tRNA-binding protein AB285_14295 ENOG4105CQ4 Transcriptional regulator AB285_14300 ENOG4105CNT hydrolase family 2 AB285_14305 ENOG4105FK9 beta-D-galactosidase beta subunit AB285_14310 ENOG4105E5D amino acid AB285_14320 ENOG4107WCA isomerase AB285_14325 ENOG4108PVD exported protein AB285_14330 ENOG4107VIJ nudix hydrolase AB285_14335 ENOG4105BZ8 glutamate synthase AB285_14345 ENOG4105BZU Histidine kinase AB285_14350 ENOG4105BZS acriflavin resistance protein AB285_14355 ENOG4105KUZ arsenate reductase AB285_14360 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AB285_14370 ENOG4106KED esterase YpfH AB285_14375 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) AB285_14380 ENOG4105CGZ zinc metallopeptidase AB285_14385 ENOG4105C8V SAICAR synthetase AB285_14390 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AB285_14400 ENOG4105RH4 Glycine cleavage system transcriptional repressor AB285_14405 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AB285_14410 ENOG4105C02 permease AB285_14415 ENOG4105ERG peptidase m48, ste24p AB285_14420 ENOG4105K89 arsenate reductase AB285_14440 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AB285_14450 ENOG4105C2W permease AB285_14455 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) AB285_14460 ENOG4105CS2 ec 3.2.1.21 AB285_14470 ENOG4108V3E phosphoribosylglycinamide formyltransferase AB285_14480 ENOG4105C9X ppx gppa phosphatase AB285_14485 ENOG4105BZU Histidine kinase AB285_14490 ENOG41062G3 Protein of unknown function (DUF2633) AB285_14505 ENOG4105Z4Q MltA-interacting MipA family protein AB285_14510 ENOG4105XJC Two component transcriptional regulator (Winged helix family AB285_14530 ENOG4105C1P efflux transporter, rnd family, mfp subunit AB285_14545 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AB285_14550 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AB285_14555 ENOG4105D4Y metalloprotease AB285_14565 ENOG4105VPD cellular component movement AB285_14575 ENOG4105DUX Transporter AB285_14580 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) AB285_14585 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AB285_14590 ENOG4105N21 Membrane AB285_14595 ENOG4105CUT histidyl-tRNA synthetase AB285_14600 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) AB285_14610 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs AB285_14630 ENOG4105QAX Iron-sulfur AB285_14635 ENOG4107QY8 reductase AB285_14640 ENOG4108JQB penicillin-binding protein 1C AB285_14645 ENOG4105DN3 alpha-2-macroglobulin domain protein AB285_14650 ENOG4105CI1 PTS System AB285_14660 ENOG4105KHC sulfurtransferase AB285_14665 ENOG4108Q3X Transcriptional regulator AB285_14670 ENOG4105YYA enhanced serine sensitivity protein SseB AB285_14675 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AB285_14680 ENOG4105WVQ Fe-S assembly protein IscX AB285_14685 ENOG4108ZIT Ferredoxin, 2FE-2S AB285_14690 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB AB285_14695 ENOG4108SWN Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity) AB285_14700 ENOG4108Z4V iron-sulfur cluster assembly AB285_14705 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins AB285_14710 ENOG4105C3J Cysteine desulfurase AB285_14715 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family AB285_14720 ENOG4105CVS RNA methyltransferase TrmH family, group 1 AB285_14725 ENOG4105ECY inositol monophosphatase AB285_14730 ENOG4105D7X high-affinity nickel-transporter AB285_14740 ENOG4108MN2 Stationary phase inducible protein CsiE AB285_14745 ENOG4105D8G Major Facilitator superfamily AB285_14750 ENOG4108SB3 DoxX Family AB285_14755 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) AB285_14765 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB285_14770 ENOG4108YZA Nitrogen regulatory protein pii AB285_14775 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB285_14780 ENOG4108SKK alpha helix protein AB285_14785 ENOG4107WP9 Histidine kinase AB285_14790 ENOG4108ETH Formylglycinamide ribotide synthetase AB285_14795 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) AB285_14800 ENOG4108Z6B deaminase AB285_14805 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB AB285_14815 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate AB285_14820 ENOG4106G6Q Transcriptional regulator AB285_14825 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AB285_14830 ENOG4105KJV Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) AB285_14835 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) AB285_14840 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) AB285_14855 ENOG4105C3F Signal peptidase i AB285_14930 ENOG4105YQ0 AB285_14955 ENOG4105UVW uncharacterized protein yebW AB285_14970 ENOG41076J9 exonuclease VIII AB285_15000 ENOG4105WMJ Positive regulator of sigma E, RseC MucC AB285_15010 ENOG41069PW sigma-e factor negative regulatory protein AB285_15020 ENOG4108IYU L-aspartate oxidase AB285_15025 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) AB285_15030 ENOG4105C1J atp-dependent rna helicase AB285_15035 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) AB285_15040 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) AB285_15045 ENOG4105EIB trna rrna methyltransferase AB285_15050 ENOG4105K63 Thioredoxin AB285_15055 ENOG4106IUH DTW domain containing protein AB285_15060 ENOG4105CD5 CoA-binding domain protein AB285_15065 ENOG4105JIM Phosphatidylserine synthase AB285_15070 ENOG4105T42 (LipO)protein AB285_15075 ENOG4105CSH Transporter AB285_15105 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB285_15110 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AB285_15115 ENOG4105C34 Pseudouridine synthase AB285_15120 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AB285_15125 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA AB285_15130 ENOG4105CQC Prephenate dehydratase AB285_15140 ENOG4105EHE chorismate mutase- prephenate dehydrogenase AB285_15145 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB285_15150 ENOG4105QP9 Protein of unknown function (DUF2799) AB285_15155 ENOG4108WS1 AB285_15160 ENOG4108KHX Diguanylate cyclase AB285_15165 ENOG41090EK ompa motb domain protein AB285_15180 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) AB285_15185 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) AB285_15190 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) AB285_15195 ENOG4105K5M 30s ribosomal protein S16 AB285_15200 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY AB285_15205 ENOG4106KVJ cytochrome C assembly protein AB285_15210 ENOG4108JU6 CBS domain protein AB285_15215 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ AB285_15225 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AB285_15230 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AB285_15235 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AB285_15240 ENOG4105VDB UPF0125 protein AB285_15245 ENOG4108Z1B Cyclase dehydrase AB285_15255 ENOG4105DFP Integrase AB285_15260 ENOG4105C4R Atp-dependent dna helicase AB285_15355 ENOG4105DFP Integrase AB285_15360 ENOG4106QCB CP4-57 prophage AB285_15365 ENOG4108P8R AB285_15395 ENOG41080ET plasmid maintenance system killer protein AB285_15400 ENOG41081XE plasmid maintenance system antidote protein, xre family AB285_15405 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB285_15420 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AB285_15425 ENOG4105DZC cytosine deaminase AB285_15430 ENOG4105C5B carbamate kinase AB285_15440 ENOG4107REC cytoplasmic protein AB285_15445 ENOG4107R1Q Membrane protein FdrA AB285_15450 ENOG4107SNB ankyrin repeat protein YahD AB285_15455 ENOG4108NUU Transcriptional regulator AB285_15460 ENOG4105VPI YqaE family transport protein AB285_15470 ENOG4108X73 DNA- binding protein AB285_15475 ENOG4108RNS Exports L-alanine (By similarity) AB285_15480 ENOG4108WMJ Protein of unknown function (DUF2002) AB285_15485 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) AB285_15490 ENOG4105WAZ (Glutaredoxin-like protein) NrdH AB285_15495 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) AB285_15500 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB285_15505 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB285_15510 ENOG4108IJ7 Glycine betaine AB285_15515 ENOG4108HQS Glycine betaine AB285_15520 ENOG4105GIJ Glycine betaine AB285_15530 ENOG4105NTK Transcriptional repressor Mpra AB285_15535 ENOG4105CW7 secretion protein, HlyD family AB285_15540 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB285_15545 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AB285_15555 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) AB285_15560 ENOG4105D9M gamma-glutamylcysteine synthetase AB285_15565 ENOG4105W39 Membrane AB285_15570 ENOG4107VXZ Hydrolase AB285_15600 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) AB285_15605 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AB285_15615 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) AB285_15620 ENOG4107TH8 cina domain protein AB285_15630 ENOG4105CC5 ABC transporter AB285_15635 ENOG4105DIK (ABC) transporter AB285_15640 ENOG4105CVE Lytic murein transglycosylase AB285_15645 ENOG410787A Pts system, glucitol sorbitol-specific AB285_15650 ENOG4105DZY Pts system, glucitol sorbitol-specific AB285_15655 ENOG4105VI0 Pts system, glucitol sorbitol-specific AB285_15660 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase AB285_15665 ENOG4105J92 DNA-binding transcriptional activator GutM AB285_15670 ENOG410804X Transcriptional regulator AB285_15680 ENOG4108JUA Transcriptional regulator AB285_15685 ENOG4108ESE uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center AB285_15690 ENOG4108EQM faD-dependent pyridine nucleotide-disulfide oxidoreductase AB285_15700 ENOG4105C8H hydrogenase maturation protein Hypf AB285_15705 ENOG4108RC0 Electron transport protein AB285_15710 ENOG4105DDV Transcriptional regulator (LacI family AB285_15715 ENOG4105C5Y PTS System AB285_15720 ENOG4105CS2 ec 3.2.1.21 AB285_15725 ENOG4108MG9 hydrogenase 3 maturation protease AB285_15730 ENOG4105I6X formate hydrogenlyase maturation AB285_15735 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit AB285_15740 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit AB285_15745 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AB285_15750 ENOG4107TDF Formate hydrogenlyase subunit 4 AB285_15755 ENOG4107R30 NADH dehydrogenase AB285_15760 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) AB285_15765 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA AB285_15770 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) AB285_15775 ENOG4107RSS Hydrogenase accessory protein HypB AB285_15780 ENOG41083WG hydrogenase assembly chaperone AB285_15785 ENOG4105CQS hydrogenase expression formation protein HypD AB285_15790 ENOG4105C45 hydrogenase expression formation protein (HypE) AB285_15800 ENOG4105VXR cytoplasmic protein AB285_15810 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) AB285_15815 ENOG4105KZM cytoplasmic protein AB285_15820 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AB285_15825 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AB285_15835 ENOG4105JQN Transcriptional regulator AB285_15840 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB285_15855 ENOG4108K5P (LipO)protein AB285_15860 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) AB285_15865 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) AB285_15870 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) AB285_15880 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) AB285_15885 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AB285_15890 ENOG4105N0Z inner membrane protein ygbE AB285_15895 ENOG4107UCJ Catalyzes the synthesis of activated sulfate (By similarity) AB285_15900 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) AB285_15910 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AB285_15915 ENOG4108MXK alkaline phosphatase isozyme conversion AB285_15920 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) AB285_15930 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AB285_15935 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase AB285_15940 ENOG41063ZK Transcriptional Regulator AraC Family AB285_15945 ENOG4105CH2 amidohydrolase AB285_15955 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AB285_15960 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) AB285_15965 ENOG4105CI1 PTS System AB285_15970 ENOG4105QEK Transcriptional regulator AB285_15980 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) AB285_15985 ENOG4105DXN mazG family AB285_15990 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AB285_15995 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AB285_16000 ENOG4105BZU Histidine kinase AB285_16005 ENOG4105BZW Glycerate kinase AB285_16010 ENOG4105EQX glucarate dehydratase AB285_16015 ENOG4105EQX glucarate dehydratase AB285_16020 ENOG4105DJB Major Facilitator Superfamily AB285_16025 ENOG4105QDK Flavodoxin AB285_16030 ENOG4105DR9 pseudouridine synthase AB285_16035 ENOG4105WP7 tRNA pseudouridine synthase C AB285_16045 ENOG4108T6E Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity) AB285_16050 ENOG4107R1K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) AB285_16055 ENOG4105EWT decarboxylase family AB285_16060 ENOG4105C44 Serine transporter AB285_16065 ENOG4105EJQ L-serine dehydratase AB285_16070 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease AB285_16075 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) AB285_16080 ENOG4105M08 Membrane AB285_16085 ENOG4105ETT transcriptional Regulator, LysR family AB285_16090 ENOG4105M5B (LipO)protein AB285_16095 ENOG4105C9B Cysteine desulfurase AB285_16100 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) AB285_16105 ENOG4105CUZ uba thif-type nad fad binding protein AB285_16110 ENOG4105CA3 membrane-bound lytic murein transglycosylase AB285_16130 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AB285_16135 ENOG4107QZM n-acetylglutamate synthase AB285_16140 ENOG4107QYX exodeoxyribonuclease v alpha AB285_16145 ENOG4107QKA exodeoxyribonuclease V beta AB285_16150 ENOG4107QXK peptidase AB285_16155 ENOG4105DSY exodeoxyribonuclease V, gamma AB285_16160 ENOG4105RVB Prepilin peptidase dependent protein c AB285_16165 ENOG4105SEN Protein of unknown function (DUF2509) AB285_16170 ENOG4105JCS prepilin peptidase dependent protein AB285_16175 ENOG4105IPU prepilin peptidase dependent protein A AB285_16180 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) AB285_16185 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) AB285_16190 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase AB285_16195 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) AB285_16200 ENOG4105IRT Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity) AB285_16205 ENOG4105SUV lipoprotein YgdR AB285_16210 ENOG4105CPC Aldo Keto reductase AB285_16215 ENOG4107S74 Lysophospholipid transporter LplT AB285_16220 ENOG4105CEY Amp-dependent synthetase and ligase AB285_16225 ENOG41060NJ transcriptional regulator AB285_16235 ENOG4105C6F GntR Family Transcriptional Regulator AB285_16240 ENOG4105CS2 ec 3.2.1.21 AB285_16245 ENOG4105CK1 PTS System AB285_16250 ENOG4105DDV Transcriptional regulator (LacI family AB285_16255 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AB285_16260 ENOG4105RQF LysR family Transcriptional regulator AB285_16275 ENOG4108QY5 Ferric enterobactin transport protein AB285_16280 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component AB285_16285 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component AB285_16300 ENOG4107QNK )-transporter AB285_16305 ENOG4105CHR reductase AB285_16310 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) AB285_16315 ENOG4105CAZ oligogalacturonide lyase AB285_16320 ENOG4108PU9 oligogalacturonate-specific porin AB285_16325 ENOG4105CHU acetyl-coa acetyltransferase AB285_16340 ENOG4108MHD transport protein AB285_16345 ENOG410830R acetyltransferase AB285_16350 ENOG4105VR1 Pfam:DUF1271 AB285_16360 ENOG4108Z9Z response to DNA damage stimulus AB285_16365 ENOG4108N8X transition metal ion binding AB285_16370 ENOG4105WEF catalase AB285_16375 ENOG4105C4M (Ubiquinol oxidase) subunit I AB285_16380 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB285_16385 ENOG4105CG3 alpha amylase, catalytic region AB285_16395 ENOG4108WTK competence damage-inducible protein AB285_16410 ENOG4108YDI single-species biofilm formation on inanimate substrate AB285_16415 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB285_16420 ENOG4105EUZ Beta-lactamase domain protein AB285_16435 ENOG4108PNB DNA-binding transcriptional regulator AB285_16440 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation AB285_16445 ENOG4105CHJ isochorismatase hydrolase AB285_16465 ENOG4108K5P (LipO)protein AB285_16470 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) AB285_16475 ENOG4105CRK lysyL-tRNA synthetase AB285_16490 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AB285_16495 ENOG4105T95 Thiol disulfide interChange protein AB285_16500 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB285_16505 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) AB285_16510 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB AB285_16515 ENOG4105Y75 tpr repeat protein AB285_16520 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) AB285_16525 ENOG4108UT2 hemolysin iii AB285_16530 ENOG4108Q3X Transcriptional regulator AB285_16535 ENOG4105CS2 ec 3.2.1.21 AB285_16545 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) AB285_16555 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AB285_16560 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB285_16565 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor AB285_16575 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) AB285_16580 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AB285_16585 ENOG4105D0A hydroxylase AB285_16590 ENOG4107RAQ aminopeptidase AB285_16600 ENOG4107YUN Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) AB285_16605 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AB285_16610 ENOG4108JQ1 Dehydrogenase AB285_16615 ENOG4105E66 phosphoriboisomerase A AB285_16620 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) AB285_16625 ENOG4105MPN Membrane AB285_16630 ENOG4108ZUB Lysine exporter protein (Lyse ygga) AB285_16635 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AB285_16640 ENOG4105D64 Mechanosensitive ion channel AB285_16645 ENOG4105D2N Aldolase AB285_16650 ENOG4105BZA Phosphoglycerate kinase AB285_16655 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AB285_16660 ENOG4105CV1 Transketolase (EC 2.2.1.1) AB285_16665 ENOG4108K0D peptidase, M48 AB285_16670 ENOG4105J5J Outer membrane porin AB285_16685 ENOG4108Q27 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity) AB285_16690 ENOG4105CHR reductase AB285_16695 ENOG410832A alpha/beta hydrolase fold AB285_16710 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase AB285_16720 ENOG4108FUF Transcriptional regulator, IclR family AB285_16725 ENOG4105CHR reductase AB285_16750 ENOG4105CYW agmatinase AB285_16755 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) AB285_16765 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP AB285_16770 ENOG4107QNK )-transporter AB285_16775 ENOG4105GPY SprT protein AB285_16780 ENOG4105RWS endonuclease I AB285_16785 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AB285_16790 ENOG4105D7Z glutathione synthase AB285_16795 ENOG4108UJU UPF0301 protein AB285_16805 ENOG4105CZX twitching motility protein AB285_16810 ENOG4105DFA alanine racemase domain protein AB285_16815 ENOG4108VIA integral membrane protein AB285_16820 ENOG4105VZ9 UPF0235 protein AB285_16830 ENOG4105CSA Coproporphyrinogen iii oxidase AB285_16835 ENOG4105WDY DNA (cytosine-5-)-methyltransferase AB285_16840 ENOG4105K33 Periplasmic Protein AB285_16845 ENOG41090ED Protein with unknown function (DUF469) AB285_16855 ENOG4105CEN a g-specific adenine glycosylase AB285_16860 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) AB285_16865 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division AB285_16870 ENOG4105EAA nucleoside AB285_16875 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase AB285_16885 ENOG4105CHY citrate lyase, alpha AB285_16890 ENOG4105CI0 Citrate lyase AB285_16895 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) AB285_16900 ENOG4105DUA (citrate (pro-3S)-lyase ligase AB285_16905 ENOG4105ERH Fumarylacetoacetate hydrolase AB285_16910 ENOG4105D2K citrate carrier protein AB285_16915 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AB285_16920 ENOG4106YYS transcriptional regulatory protein AB285_16925 ENOG4105CXN decarboxylase AB285_16930 ENOG4108UQV Membrane AB285_17030 ENOG4108ZXE AB285_17045 ENOG4105BZU Histidine kinase AB285_17050 ENOG4105WH1 Two component transcriptional regulator luxr family AB285_17070 ENOG4108TUY outer membrane protein PgaA AB285_17075 ENOG4107BJW polysaccharide deacetylase AB285_17080 ENOG4105CND Glycosyl transferase, family 2 AB285_17090 ENOG4106032 Glutathionylspermidine synthase AB285_17095 ENOG4105CYM Glutathione S-transferase AB285_17100 ENOG4107EDW L-fucose operon activator AB285_17105 ENOG4105C8Q Methyl-accepting chemotaxis AB285_17110 ENOG4105CPC Aldo Keto reductase AB285_17115 ENOG4108TEB UPF0114 protein AB285_17135 ENOG4108ZZF transport protein (ExbD) AB285_17140 ENOG4105CWK Biopolymer transport protein, ExbB AB285_17145 ENOG4105C28 cystathionine AB285_17150 ENOG4108K81 inner membrane protein YghB AB285_17155 ENOG4105CF7 AraC family transcriptional regulator AB285_17160 ENOG4108I6A alcohol dehydrogenase AB285_17165 ENOG4105CV8 reductase AB285_17190 ENOG4108ZSJ is1 orf2 AB285_17240 ENOG4108YXQ IS66 Orf2 family protein AB285_17265 ENOG4107QN2 dihydrolipoyl dehydrogenase AB285_17280 ENOG4108SF5 RNA Polymerase AB285_17285 ENOG4108S3W Anti-feci sigma factor, fecr AB285_17290 ENOG4105GAV receptor AB285_17295 ENOG4108HUF Transporter AB285_17300 ENOG4105DQ5 transport system permease protein AB285_17305 ENOG4108IHU transport system permease protein AB285_17310 ENOG4105E0A ABC, transporter AB285_17315 ENOG4108YXQ IS66 Orf2 family protein AB285_17330 ENOG4105EQR Transposase IS116 IS110 IS902 AB285_17335 ENOG4105CIS alcohol dehydrogenase AB285_17340 ENOG4105ETE Transcriptional regulator (LacI family AB285_17350 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) AB285_17355 ENOG4108UW5 maltose o-acetyltransferase AB285_17365 ENOG4105E2A Dehydrogenase AB285_17370 ENOG4105F2I Transposase AB285_17415 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) AB285_17420 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase AB285_17425 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB285_17430 ENOG4105H4F exported protein AB285_17435 ENOG4105XJC Two component transcriptional regulator (Winged helix family AB285_17440 ENOG4105DHQ Histidine kinase AB285_17445 ENOG4105NF4 modulator of drug activity AB285_17450 ENOG4105VRH Antibiotic biosynthesis monooxygenase AB285_17455 ENOG4109066 lysm domain bon superfamily protein AB285_17460 ENOG4105EP8 Glycosyl Hydrolase Family 88 AB285_17465 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) AB285_17495 ENOG4105DQ5 transport system permease protein AB285_17500 ENOG4105E0A ABC, transporter AB285_17510 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB285_17515 ENOG4105IPS esterase AB285_17520 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AB285_17525 ENOG4108SX3 cytoplasmic protein AB285_17530 ENOG41087AY ADP-Ribose pyrophosphatase AB285_17540 ENOG4105F1G UPF0441 protein AB285_17545 ENOG4106032 Glutathionylspermidine synthase AB285_17550 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AB285_17560 ENOG4106UBK fimbrial-like adhesin protein AB285_17565 ENOG4106PG1 outer membrane usher protein AB285_17570 ENOG4108TTM chaperone AB285_17575 ENOG4108MY7 Fimbrial AB285_17580 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AB285_17585 ENOG4105W0Z cytoplasmic protein AB285_17590 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) AB285_17595 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) AB285_17600 ENOG4105I7R Adenylate cyclase AB285_17605 ENOG4106MWK domain protein AB285_17610 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate AB285_17620 ENOG4107ZVW dihydroneopterin aldolase AB285_17630 ENOG4105C54 Major Facilitator superfamily AB285_17635 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) AB285_17640 ENOG4108YZ9 Urea amidohydrolase subunit gamma AB285_17645 ENOG4105KI2 Urea amidohydrolase subunit beta AB285_17650 ENOG4105CQM Urea amidohydrolase subunit alpha AB285_17655 ENOG4105MMR Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) AB285_17665 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) AB285_17670 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) AB285_17675 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AB285_17680 ENOG4105VCC 30S ribosomal protein S21 AB285_17685 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AB285_17690 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB285_17695 ENOG4108VCA G U mismatch-specific DNA glycosylase AB285_17745 ENOG4105UZW Tail fiber assembly protein AB285_17750 ENOG4108X9F tail fiber protein AB285_17835 ENOG4105ED4 portal protein AB285_17845 ENOG4105NI8 Cytosine-specific methyltransferase AB285_17855 ENOG4105VZ1 Replication Protein AB285_17860 ENOG4105KSC Transcriptional regulator, TraR DksA family AB285_17890 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB285_17900 ENOG4105Q26 Siderophore-interacting protein AB285_17905 ENOG4105NTW Transcriptional regulator AB285_17910 ENOG4105C8Q Methyl-accepting chemotaxis AB285_17915 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AB285_17920 ENOG4105C8Y Acetylornithine aminotransferase AB285_17930 ENOG4106EAR Fimbrial protein AB285_17940 ENOG4105CW0 outer membrane usher protein AB285_17950 ENOG4105Q7J Fimbrial AB285_17960 ENOG4106PH7 chaperone AB285_17975 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound AB285_17980 ENOG41061GT Aldolase AB285_17985 ENOG4105D4B ABC, transporter AB285_17990 ENOG4105F5R ABC transporter AB285_17995 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AB285_18000 ENOG4105C2J ABC transporter AB285_18005 ENOG4105DKT Transcriptional regulator AB285_18010 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) AB285_18015 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB285_18020 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) AB285_18025 ENOG4108VKG metal-dependent hydrolase AB285_18030 ENOG4105EE0 oxidoreductase AB285_18035 ENOG4105DU1 integral membrane protein, terc AB285_18045 ENOG4105CTX dehydratase AB285_18055 ENOG4105DPW Major facilitator superfamily MFS_1 AB285_18060 ENOG4107YCY Transcriptional regulator AB285_18065 ENOG4106W5V Membrane AB285_18070 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) AB285_18075 ENOG4105WAY exported protein AB285_18080 ENOG4105NE1 Conserved Protein AB285_18085 ENOG41090KG Inner membrane protein YqjE AB285_18090 ENOG4105YJD AB285_18095 ENOG4108VBZ doxx family AB285_18100 ENOG4105CHF Glutathione S-transferase AB285_18105 ENOG4105KAF membrAne AB285_18110 ENOG4105CWB LysR family transcriptional Regulator AB285_18115 ENOG4108CNN domain protein AB285_18125 ENOG4105C44 Serine transporter AB285_18130 ENOG4105C6N Formate acetyltransferase AB285_18135 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AB285_18140 ENOG4108MST Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity) AB285_18145 ENOG4105C7B Threonine dehydratase AB285_18150 ENOG410811B TRANSCRIPTIONal AB285_18155 ENOG4105BZW Glycerate kinase AB285_18160 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AB285_18165 ENOG4105CNV Aldolase AB285_18170 ENOG4105CTX dehydratase AB285_18175 ENOG4105E98 transcriptional regulator DeoR family AB285_18180 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of AB285_18185 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB AB285_18195 ENOG4105F3R pts system mannose fructose sorbose family iid AB285_18200 ENOG4105YHU PTS system AB285_18205 ENOG4105CE4 GlcNAc 6-P deacetylase AB285_18210 ENOG4105E70 isomerase AB285_18215 ENOG4105D2N Aldolase AB285_18220 ENOG4105CI1 PTS System AB285_18235 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AB285_18240 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) AB285_18245 ENOG41082RQ UPF0102 protein AB285_18250 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) AB285_18255 ENOG4105W4M Transport-associated protein AB285_18260 ENOG4107S21 permease AB285_18265 ENOG4105K4T epimerase AB285_18270 ENOG4107R7Y intracellular protease Pfpi family AB285_18275 ENOG4108ZPB UPF0306 protein AB285_18280 ENOG41082IR Excinuclease ABC C subunit domain protein AB285_18285 ENOG4108YYD acetyltransferase AB285_18290 ENOG4105XPQ lipid carrier protein AB285_18295 ENOG4105CFP Peptidase U32 AB285_18300 ENOG4106RZ4 Peptidase U32 AB285_18305 ENOG4105DEN Luciferase family AB285_18310 ENOG4105CIC tryptophan-specific transport protein AB285_18315 ENOG4105C1J atp-dependent rna helicase AB285_18325 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) AB285_18330 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) AB285_18335 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AB285_18340 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) AB285_18345 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) AB285_18350 ENOG4105CHV Transcription elongation factor NusA AB285_18355 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) AB285_18365 ENOG4105CDH Citrulline--aspartate ligase AB285_18380 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) AB285_18385 ENOG4105EEI dihydropteroate synthase AB285_18390 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AB285_18395 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) AB285_18400 ENOG4105HBR Rna-binding protein AB285_18405 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) AB285_18410 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase AB285_18425 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control AB285_18430 ENOG4105QYV Membrane AB285_18435 ENOG4105K46 50S ribosomal protein l27 AB285_18445 ENOG4105EAH synthase AB285_18450 ENOG4105HVQ Regulatory factor of maltose metabolism AB285_18455 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AB285_18460 ENOG4105VFK BolA family AB285_18465 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane AB285_18470 ENOG4105E3I toluene tolerance AB285_18475 ENOG4107PE3 Mammalian cell entry related domain protein AB285_18480 ENOG4105CY3 ABC transporter, permease AB285_18485 ENOG4105DHJ ABC, transporter AB285_18490 ENOG4105FEU K -dependent Na -Ca exchanger AB285_18495 ENOG4105C2X Arabinose 5-phosphate isomerase AB285_18500 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase AB285_18505 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) AB285_18510 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA AB285_18515 ENOG4108IUZ ABC transporter AB285_18520 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB285_18525 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA AB285_18530 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN AB285_18535 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) AB285_18540 ENOG41080Z8 PHOSPHOCARRIER protein AB285_18545 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase AB285_18550 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain AB285_18555 ENOG4105BZU Histidine kinase AB285_18560 ENOG4108K5H permease YjgP YjgQ family protein AB285_18565 ENOG4108M8S permease YjgP YjgQ family protein AB285_18570 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AB285_18575 ENOG4105MYG DNA polymerase iii, chi subunit AB285_18580 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AB285_18585 ENOG4108MJ3 acetyltransferase AB285_18590 ENOG4105DQ4 alcohol dehydrogenase AB285_18600 ENOG4105D7A ATP-binding protein AB285_18605 ENOG4105N5T Radical SAM Protein AB285_18610 ENOG4105CBC glutamate synthase AB285_18615 ENOG4105BZ8 glutamate synthase AB285_18620 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin AB285_18625 ENOG4105DZC cytosine deaminase AB285_18630 ENOG4108R66 Conserved Protein AB285_18635 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) AB285_18640 ENOG4105JHE Major Facilitator Superfamily AB285_18645 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB285_18650 ENOG4108QBF Transcriptional regulator AB285_18655 ENOG4105KB2 stringent starvation protein b AB285_18660 ENOG4107MKT Stringent starvation protein a AB285_18665 ENOG4108UJD 30S ribosomal protein S9 AB285_18675 ENOG4105D6Z AFG1 family ATPase AB285_18680 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III AB285_18685 ENOG4105C0H protease AB285_18690 ENOG4105C0H protease AB285_18700 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) AB285_18705 ENOG4105RID UPF0379 protein yhcN AB285_18710 ENOG4105UNR (Barnase) inhibitor AB285_18715 ENOG4105C26 Dehydrogenase AB285_18720 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) AB285_18735 ENOG4105CR8 Transcriptional regulator AB285_18740 ENOG4105R3P Inner membrane protein yagU AB285_18745 ENOG4105D1U peptidase U62 modulator of DNA gyrase AB285_18750 ENOG4105QD6 exported protein AB285_18755 ENOG4105C03 ribonuclease AB285_18765 ENOG4105VQ7 Rod shape-determining protein MreD AB285_18770 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AB285_18775 ENOG4105DFF Rod shape-determining protein mreb AB285_18780 ENOG41062P1 Diguanylate cyclase phosphodiesterase AB285_18785 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family AB285_18795 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) AB285_18800 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) AB285_18805 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AB285_18810 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AB285_18815 ENOG4105RG0 Membrane AB285_18820 ENOG4108IA2 Sodium pantothenate symporter AB285_18825 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) AB285_18835 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AB285_18840 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) AB285_18845 ENOG41061ME transport protein AB285_18855 ENOG4108XG4 DNA-binding transcriptional regulator AB285_18860 ENOG4105C1P efflux transporter, rnd family, mfp subunit AB285_18865 ENOG4105BZS acriflavin resistance protein AB285_18870 ENOG4105XCM membrane LIPOPROTEIN AB285_18910 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) AB285_18915 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) AB285_18920 ENOG4108Y73 Membrane AB285_18925 ENOG4105EJ2 Transcriptional regulator AB285_18935 ENOG4105C5Q Transcriptional regulator AB285_18940 ENOG4105CH7 arginosuccinase AB285_18945 ENOG4105CAS nag kinase AB285_18950 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AB285_18955 ENOG4105CWC Acetylornithine deacetylase AB285_18960 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) AB285_18970 ENOG4105DCT glycerol dehydrogenase AB285_18975 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) AB285_18980 ENOG4105SYT Methylenetetrahydrofolate reductase AB285_18985 ENOG4105CFH Aspartokinase AB285_18990 ENOG4105C28 cystathionine AB285_18995 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) AB285_19000 ENOG4105VFB Binds the 23S rRNA (By similarity) AB285_19005 ENOG4105C25 Primosomal protein n' AB285_19010 ENOG4105ETE Transcriptional regulator (LacI family AB285_19015 ENOG41063M6 Cell Division Protein AB285_19030 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AB285_19035 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) AB285_19045 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) AB285_19050 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AB285_19060 ENOG4105CBT Fructose-1,6-bisphosphatase AB285_19065 ENOG4105DP0 ferredoxin-NADP reductase AB285_19070 ENOG4108VTS Membrane AB285_19075 ENOG4105EBK exported protein AB285_19080 ENOG4105CP7 Triose-phosphate isomerase AB285_19090 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) AB285_19095 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AB285_19100 ENOG4105CTQ phosphohexokinase AB285_19105 ENOG41076HS cation diffusion facilitator family transporter AB285_19110 ENOG4105FMW periplasmic AB285_19115 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB285_19120 ENOG4105E0F Histidine kinase AB285_19125 ENOG4108RPX mosc domain containing protein AB285_19130 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB285_19135 ENOG4107YRA Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity) AB285_19140 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) AB285_19145 ENOG4107S4Z Activates expression of the rhaBAD and rhaT operons (By similarity) AB285_19155 ENOG4105DET Rhamnulokinase AB285_19160 ENOG4105DKG l-rhamnose isomerase AB285_19165 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) AB285_19170 ENOG4105D4B ABC, transporter AB285_19175 ENOG4105C2J ABC transporter AB285_19180 ENOG4105CNN ABC, transporter AB285_19185 ENOG4105F5R ABC transporter AB285_19190 ENOG4105C0A alcohol dehydrogenase AB285_19200 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) AB285_19220 ENOG4108UMN azlc family AB285_19235 ENOG4105E6S usher protein( AB285_19240 ENOG4108S1B Periplasmic chaperone protein AB285_19260 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB285_19265 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB285_19270 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AB285_19275 ENOG4108MG3 formate dehydrogenase AB285_19280 ENOG4105F46 Necessary for formate dehydrogenase activity (By similarity) AB285_19290 ENOG41068KX affects formate dehydrogenase-N AB285_19300 ENOG4105SUU thioesterase domain AB285_19310 ENOG4107S2Z UPF0761 membrane protein AB285_19315 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 AB285_19320 ENOG4105E98 transcriptional regulator DeoR family AB285_19325 ENOG4108MGF sugar kinase AB285_19330 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AB285_19335 ENOG4105D2M Aldolase AB285_19340 ENOG4107QKS N-acylglucosamine 2-epimerase AB285_19345 ENOG4105CJQ hydrolase, family 31 AB285_19350 ENOG4105CT4 transporter AB285_19355 ENOG4105CT4 transporter AB285_19360 ENOG4105EQR Transposase IS116 IS110 IS902 AB285_19365 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is AB285_19375 ENOG4105C5F glutamine synthetase AB285_19380 ENOG4105CUX Signal transduction histidine kinase AB285_19385 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB285_19390 ENOG4106FIY AB285_19395 ENOG4105D4P Coproporphyrinogen iii oxidase AB285_19400 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) AB285_19405 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) AB285_19410 ENOG4105C2M dna polymerase I AB285_19415 ENOG4106HNH Acyl-transferase AB285_19425 ENOG4105E27 serine threonine protein kinase AB285_19430 ENOG4105PC1 Conserved Protein AB285_19435 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) AB285_19440 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b AB285_19465 ENOG4108Z0R Transferase AB285_19470 ENOG4105SG3 Protein of unknown function (DUF1488) AB285_19475 ENOG4105E2X shikimate dehydrogenase AB285_19480 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AB285_19485 ENOG4108WI1 Dna topoisomerase AB285_19490 ENOG4108RPN Protein smg homolog AB285_19495 ENOG4105C79 DNA protecting protein DprA AB285_19500 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AB285_19505 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) AB285_19510 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AB285_19515 ENOG4105C1A potassium transporter peripheral membrane AB285_19520 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) AB285_19525 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system AB285_19530 ENOG4105W1Y Transcriptional regulator AB285_19535 ENOG4105VTS DnaJ-like, subfamily C AB285_19545 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB285_19555 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) AB285_19565 ENOG41067V7 50S ribosomal protein L36 AB285_19570 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AB285_19580 ENOG4105VPB 50S ribosomal protein L30 AB285_19585 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) AB285_19595 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) AB285_19600 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) AB285_19605 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) AB285_19615 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) AB285_19620 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) AB285_19625 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal AB285_19630 ENOG41083MP 50s ribosomal protein l29 AB285_19635 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) AB285_19640 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) AB285_19650 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) AB285_19665 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) AB285_19685 ENOG4108UQY Iron-storage protein AB285_19690 ENOG4105W53 bacterioferritin-associated ferredoxin AB285_19695 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AB285_19700 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) AB285_19715 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) AB285_19720 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) AB285_19725 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) AB285_19730 ENOG4105WWK YheO domain protein AB285_19735 ENOG4108V1T peptidylprolyl cis-trans isomerase AB285_19740 ENOG4105VRX Protein slyX homolog AB285_19745 ENOG4108YZY peptidylprolyl cis-trans isomerase AB285_19750 ENOG4105VKU nucleicacid-binding protein AB285_19755 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB285_19760 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AB285_19765 ENOG4105C5H ABC transporter AB285_19770 ENOG4108K70 Transcriptional regulator AB285_19775 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AB285_19780 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase AB285_19785 ENOG4107TT2 Auxin Efflux Carrier AB285_19820 ENOG4105DNZ Alpha Beta Hydrolase AB285_19825 ENOG4105YP7 UPF0270 protein AB285_19830 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) AB285_19835 ENOG4108UKZ OsmC family AB285_19845 ENOG410613R integral membrane protein, YccS YhfK family AB285_19850 ENOG4105C8Y Acetylornithine aminotransferase AB285_19855 ENOG4105DDQ anthranilate synthase AB285_19860 ENOG4105MZU cell filamentation protein AB285_19865 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AB285_19870 ENOG4106DTQ Protein TsgA homolog AB285_19875 ENOG4107QZF nitrite reductase NADPH large subunit AB285_19880 ENOG4105WZK nitrite reductase NADPH small subunit AB285_19885 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AB285_19890 ENOG4105VYH AB285_19895 ENOG4105C31 Tryptophanyl-tRNA synthetase AB285_19905 ENOG4105DJV ribulose-phosphate 3-epimerase AB285_19910 ENOG4105DFE Dna adenine methylase AB285_19915 ENOG4105EGB membrane protein DamX AB285_19920 ENOG4105D49 3-dehydroquinate synthase AB285_19925 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) AB285_19935 ENOG4105E4G Type IV pilus AB285_19955 ENOG4108U1Q Pilus assembly protein AB285_19960 ENOG4108JQC penicillin-binding protein 1A AB285_19965 ENOG4107RK2 ADP-ribose diphosphatase NudE AB285_19975 ENOG4105DQY intracellular growth attenuator AB285_19980 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 AB285_19985 ENOG4105VEJ Heat shock protein AB285_19990 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) AB285_19995 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase AB285_20000 ENOG4105E0F Histidine kinase AB285_20005 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AB285_20010 ENOG4108RRZ Transcription elongation factor GreB AB285_20015 ENOG4105BZM domain protein AB285_20020 ENOG4105XFK Ferrous iron transport protein A AB285_20030 ENOG41060N5 May function as a transcriptional regulator that controls feoABC expression (By similarity) AB285_20035 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) AB285_20040 ENOG4105MJ2 Competence protein AB285_20050 ENOG4105C6Z Gluconate AB285_20055 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) AB285_20060 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AB285_20070 ENOG4105E98 transcriptional regulator DeoR family AB285_20075 ENOG4105EBW Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity) AB285_20080 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) AB285_20090 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AB285_20095 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AB285_20100 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) AB285_20105 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) AB285_20110 ENOG4108ESZ Glycogen debranching enzyme AB285_20115 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) AB285_20120 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AB285_20130 ENOG41076UM multiple antibiotic resistance (MarC)-related protein AB285_20135 ENOG4105C6Z Gluconate AB285_20140 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AB285_20145 ENOG4105DIQ Transcriptional regulator AB285_20150 ENOG4105C2I pirin domain protein AB285_20155 ENOG4105D9R oxidoreductase AB285_20160 ENOG4105WCN acetyltransferase AB285_20165 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AB285_20170 ENOG4105WC8 Conserved Protein AB285_20175 ENOG4107T6V glycerophosphoryl diester phosphodiesterase AB285_20190 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component AB285_20195 ENOG4105BZ7 extracellular solute-binding protein family 1 AB285_20200 ENOG4108IV0 ABC, transporter AB285_20205 ENOG4105C0Z ABC transporter AB285_20210 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AB285_20215 ENOG4105C32 Amino acid ABC transporter (Permease) AB285_20220 ENOG4105CP9 extracellular ligand-binding receptor AB285_20235 ENOG4105U59 -acetyltransferase AB285_20240 ENOG4105CP9 extracellular ligand-binding receptor AB285_20245 ENOG4108JPW Aminotransferase AB285_20250 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB285_20255 ENOG4105CRP Part of the ABC transporter FtsEX involved in AB285_20260 ENOG4105CAK Cell division ATP-binding protein ftsE AB285_20265 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AB285_20270 ENOG4106H78 methyltransferase AB285_20275 ENOG4105MG3 Membrane AB285_20285 ENOG4107FS9 Membrane AB285_20290 ENOG4105C59 p-type ATPase AB285_20295 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AB285_20305 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AB285_20310 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) AB285_20315 ENOG4105EX9 Membrane AB285_20320 ENOG4108W1V Lipoprotein AB285_20325 ENOG4105DSF transport protein AB285_20365 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) AB285_20390 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB285_20400 ENOG4105C2D reductase AB285_20405 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AB285_20410 ENOG4107YAK holo-(acyl carrier protein) synthase 2 AB285_20415 ENOG4105PE8 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) AB285_20430 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) AB285_20435 ENOG4105C3I Nad-dependent epimerase dehydratase AB285_20440 ENOG4105CKK Glycosyl transferase, family 2 AB285_20460 ENOG41083B3 HAD-superfamily subfamily IB hydrolase AB285_20465 ENOG4105EWI Short-chain dehydrogenase reductase Sdr AB285_20470 ENOG4105ETT transcriptional Regulator, LysR family AB285_20475 ENOG4105PY6 Phenolic acid decarboxylase AB285_20490 ENOG4105DR5 peptidase AB285_20520 ENOG410624V efflux system protein AB285_20600 ENOG4105CBX hi0933 family AB285_20605 ENOG4105CJ3 phosphate transporter AB285_20615 ENOG4108M6U Universal stress protein A AB285_20620 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) AB285_20625 ENOG4105DGW oligopeptidase A AB285_20630 ENOG4105D6S protein involved in catabolism of external DNA AB285_20635 ENOG4105DC8 reductase AB285_20665 ENOG4106S2D Transcriptional regulator AB285_20670 ENOG4105CHR reductase AB285_20675 ENOG4105CBN LysR family transcriptional regulator AB285_20680 ENOG4107H3J ribonuclease AB285_20685 ENOG4105CSH Transporter AB285_20690 ENOG41066T0 asmA family AB285_20695 ENOG4105CMB EAL domain-containing protein AB285_20700 ENOG4107SS6 2-dehydro-3-deoxygluconokinase AB285_20705 ENOG4105CS0 peptidase AB285_20710 ENOG4105CK2 sodium dicarboxylate symporter AB285_20715 ENOG4105BZU Histidine kinase AB285_20720 ENOG4105EJG cellulose synthase AB285_20725 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) AB285_20730 ENOG4107EEX Cellulose synthase regulator protein AB285_20740 ENOG4105UTS cellulose synthase operon protein YhjQ AB285_20745 ENOG410661M cytoplasmic protein AB285_20750 ENOG4105U74 cellulose biosynthesis protein BcsE AB285_20755 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT AB285_20760 ENOG4105D1V cellulose synthase operon protein YhjU AB285_20765 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase AB285_20770 ENOG4105D4A Cell wall formation (By similarity) AB285_20800 ENOG4108RR8 protoporphyrinogen oxidase AB285_20805 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) AB285_20810 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AB285_20815 ENOG4105D9Y Splits dipeptides with a prolyl residue in the C- terminal position (By similarity) AB285_20820 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB285_20825 ENOG4105CHU acetyl-coa acetyltransferase AB285_20830 ENOG4105C38 Glycyl-tRNA synthetase beta subunit AB285_20835 ENOG4107QIB glycyl-tRNA synthetase, alpha subunit AB285_20845 ENOG4105MEV Acyl-transferase AB285_20850 ENOG4105CMG Carbohydrate kinase AB285_20855 ENOG4105C93 Xylose Isomerase AB285_20860 ENOG4105DFW ABC transporter AB285_20865 ENOG4105C2J ABC transporter AB285_20870 ENOG4107RNG ABC transporter AB285_20875 ENOG4105T16 Transcriptional regulator (AraC family) AB285_20880 ENOG4108UR8 BAX protein AB285_20885 ENOG4107T9C Alpha amylase catalytic region AB285_20890 ENOG4105JKW Valine--pyruvate aminotransferase AB285_20895 ENOG4108XIB electron transport protein ysaA AB285_20900 ENOG4105J4Q Transcriptional regulator AB285_20905 ENOG4105DG4 malate L-lactate dehydrogenase AB285_20910 ENOG4108R66 Conserved Protein AB285_20915 ENOG4108M5W AB285_20920 ENOG4105DJB Major Facilitator Superfamily AB285_20925 ENOG4105CMG Carbohydrate kinase AB285_20930 ENOG4105H6Q decarboxylase AB285_20935 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase AB285_20940 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AB285_20945 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) AB285_20950 ENOG4105CT4 transporter AB285_20960 ENOG4105C26 Dehydrogenase AB285_20965 ENOG41066F8 ROK family AB285_20970 ENOG4105EM7 Selenocysteine-specific translation elongation factor AB285_20980 ENOG4108U78 Glutathione S-transferase AB285_20985 ENOG4105CTS PTS system mannitol-specific AB285_20995 ENOG4105E61 Mannitol repressor protein AB285_21000 ENOG4108YYI Protein of unknown function (DUF2810) AB285_21010 ENOG4105CW0 outer membrane usher protein AB285_21015 ENOG4108VCD Chaperone AB285_21020 ENOG4108S54 Fimbrial protein AB285_21025 ENOG4105DAA L-lactate AB285_21030 ENOG41073TP transcriptional regulator AB285_21035 ENOG4105DMF Dehydrogenase AB285_21040 ENOG4105D2S major facilitator superfamily AB285_21045 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AB285_21055 ENOG4105EMY transcriptional regulator AB285_21060 ENOG4105C7B Threonine dehydratase AB285_21070 ENOG4105CM2 brancheD-chain amino acid aminotransferase AB285_21075 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit AB285_21085 ENOG4105C0P Mg chelatase subunit ChlI AB285_21090 ENOG4108WFC UPF0438 protein yifE AB285_21135 ENOG4107EJG GntR family transcriptional regulator AB285_21140 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB285_21145 ENOG4105ETE Transcriptional regulator (LacI family AB285_21150 ENOG4108RVA ribokinase AB285_21155 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AB285_21160 ENOG4105CNN ABC, transporter AB285_21165 ENOG4105C2J ABC transporter AB285_21170 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) AB285_21175 ENOG4105DFH Transport of potassium into the cell (By similarity) AB285_21185 ENOG4105EV2 VWA domain protein interacting with AAA ATPase AB285_21190 ENOG4105CU9 asparagine synthetase A AB285_21195 ENOG4108VVK transcriptional Regulator, AsnC AB285_21200 ENOG4105QTB Flavodoxin AB285_21205 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) AB285_21210 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) AB285_21215 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation AB285_21220 ENOG4105EE4 it plays a direct role in the translocation of protons across the membrane (By similarity) AB285_21225 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB285_21230 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB285_21235 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB285_21240 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) AB285_21250 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) AB285_21255 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) AB285_21260 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) AB285_21265 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AB285_21270 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) AB285_21275 ENOG4105C8U phosphate abc transporter AB285_21280 ENOG4105E2Z phosphate ABC transporter (Permease AB285_21285 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AB285_21295 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 AB285_21300 ENOG4105C7N Xanthine uracil vitamin C permease AB285_21305 ENOG4108YYH Nadph-dependent fmn reductase AB285_21310 ENOG4105E8Q phosphopantetheinyl transferase AB285_21315 ENOG4105G2Y Transcriptional regulator AB285_21320 ENOG4105CNH Multidrug resistance protein MdtL AB285_21325 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) AB285_21330 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AB285_21335 ENOG4105NVJ RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) AB285_21350 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AB285_21355 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) AB285_21360 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB285_21365 ENOG4107YCY Transcriptional regulator AB285_21370 ENOG4105DIA mandelate racemase muconate lactonizing AB285_21375 ENOG4105DEI Mannitol dehydrogenase AB285_21380 ENOG4105CPQ Dehydrogenase AB285_21385 ENOG4105DG4 malate L-lactate dehydrogenase AB285_21390 ENOG4108I5G Major Facilitator superfamily AB285_21395 ENOG410667J hydrolase AB285_21400 ENOG4105EMF GntR family transcriptional regulator AB285_21405 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 AB285_21410 ENOG4108RTU Aldolase AB285_21415 ENOG4105CXK mandelate racemase muconate lactonizing AB285_21420 ENOG4105DJB Major Facilitator Superfamily AB285_21425 ENOG4105D99 atp gtp-binding protein AB285_21430 ENOG4105R2A (LipO)protein AB285_21440 ENOG4108SHS Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity) AB285_21445 ENOG4105D0C transport protein AB285_21450 ENOG4105FDP GntR family transcriptional regulator AB285_21455 ENOG4105CI1 PTS System AB285_21460 ENOG4105F8D glycoside hydrolase family 4 AB285_21465 ENOG4105VG5 Membrane AB285_21470 ENOG4105JP4 Inner membrane protein yidG AB285_21475 ENOG4105BZC d-serine deaminase AB285_21485 ENOG4105W8I Transcriptional regulator AB285_21575 ENOG4105KPY Small multidrug resistance protein AB285_21585 ENOG4106NZI LysR family Transcriptional regulator AB285_21595 ENOG41062JF Transcriptional regulator AB285_21625 ENOG4105DHJ ABC, transporter AB285_21715 ENOG4108YGG dna repair protein AB285_21720 ENOG4105DFS Conserved Protein AB285_21730 ENOG4105E5M Multidrug resistance protein D AB285_21750 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase AB285_21755 ENOG4108Z3N Transcriptional regulator AB285_21760 ENOG4105C7K acetolactate synthase AB285_21765 ENOG4105M71 acetolactate synthase 1 regulatory subunit AB285_21770 ENOG4108KX4 response regulator AB285_21775 ENOG4105BZU Histidine kinase AB285_21780 ENOG4105CXY transporter AB285_21785 ENOG4105CXY transporter AB285_21790 ENOG4105CPT Alpha beta hydrolase AB285_21800 ENOG4108SAJ Protein of unknown function (DUF1198) AB285_21815 ENOG4108UZ3 Transporter AB285_21820 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) AB285_21825 ENOG4105VCP PTS System AB285_21830 ENOG4105CS2 ec 3.2.1.21 AB285_21835 ENOG4105CK1 PTS System AB285_21845 ENOG4105ETE Transcriptional regulator (LacI family AB285_21855 ENOG4105C2C drug resistance transporter, Bcr CflA AB285_21860 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AB285_21865 ENOG4105BZS acriflavin resistance protein AB285_21870 ENOG4105C1P efflux transporter, rnd family, mfp subunit AB285_21875 ENOG41067SE Tetr family transcriptional regulator AB285_21880 ENOG4105VEV -acetyltransferase AB285_21885 ENOG4108IG5 Transcriptional regulator AB285_21895 ENOG4105D01 (LipO)protein AB285_21920 ENOG4105CW0 outer membrane usher protein AB285_21925 ENOG4108MQF Chaperone AB285_21945 ENOG4108GWT fimbrillin MatB AB285_21955 ENOG4108N3D putative enzyme AB285_21990 ENOG4108MBX Secretion Protein AB285_21995 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein AB285_22005 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) AB285_22010 ENOG4107SEY Conserved Protein AB285_22015 ENOG4105VT2 5-hydroxyisourate hydrolase AB285_22020 ENOG4108XDN Transcriptional regulator AB285_22040 ENOG4105CW0 outer membrane usher protein AB285_22045 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae AB285_22050 ENOG4108RQP Major type 1 subunit fimbrin AB285_22070 ENOG4105ECQ AraC Family Transcriptional Regulator AB285_22075 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB285_22110 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures AB285_22115 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles AB285_22120 ENOG4105ZS6 Protein of unknown function (DUF987) AB285_22125 ENOG4108XS9 dna repair protein AB285_22130 ENOG4106H6R UPF0380 protein AB285_22160 ENOG4105CHH sulfate transporter AB285_22180 ENOG4105CAU Arsenical resistance protein, ArsH AB285_22250 ENOG4105DFP Integrase AB285_22260 ENOG4105CT4 transporter AB285_22265 ENOG4105CJQ hydrolase, family 31 AB285_22270 ENOG4105JV1 AsmA family AB285_22275 ENOG4105C2W permease AB285_22280 ENOG4105D6U Sodium Glutamate Symporter AB285_22285 ENOG4105CB5 ATP-dependent DNA helicase recG AB285_22290 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase AB285_22295 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AB285_22300 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) AB285_22310 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) AB285_22320 ENOG4108Y9B (LipO)protein AB285_22325 ENOG4108W78 Pfam:DUF1017 AB285_22330 ENOG4105E3R (LipO)protein AB285_22340 ENOG4107ZF2 Phosphatase AB285_22345 ENOG4108F2G Chain length determinant protein AB285_22350 ENOG4105EN6 Membrane AB285_22355 ENOG4105DSJ YicC domain protein AB285_22365 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) AB285_22375 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) AB285_22380 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AB285_22385 ENOG4105W5Q DNA repair protein (RadC AB285_22390 ENOG4105KDC 50s ribosomal protein l28 AB285_22395 ENOG4105W0E 50S ribosomal protein L33 AB285_22400 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) AB285_22405 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) AB285_22410 ENOG4106WTF Glycosyl transferase, family 2 AB285_22415 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase AB285_22420 ENOG4105K64 Glycosyl transferase, family 2 AB285_22425 ENOG4105CPK Glycosyl transferase (Group 1 AB285_22435 ENOG4105DKP glycosyl transferase, family 9 AB285_22455 ENOG4105D16 lipopolysaccharide heptosyltransferase i AB285_22460 ENOG4105XA0 heptosyltransferase ii AB285_22465 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) AB285_22470 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AB285_22475 ENOG4105CPQ Dehydrogenase AB285_22485 ENOG4107TAE Glycosyl transferase (Group 1 AB285_22490 ENOG4106WTF Glycosyl transferase, family 2 AB285_22495 ENOG4105PXI polysaccharide deacetylase AB285_22500 ENOG41063SB peptidase AB285_22505 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AB285_22510 ENOG4107YZP Rhodanese domain protein AB285_22515 ENOG4105VW4 glutaredoxin 3 AB285_22520 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) AB285_22525 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase AB285_22530 ENOG4105D7W serine acetyltransferase AB285_22535 ENOG4105KQ5 peptidylprolyl cis-trans isomerase AB285_22540 ENOG4105C4R Atp-dependent dna helicase AB285_22545 ENOG4105C9X ppx gppa phosphatase AB285_22555 ENOG4105K63 Thioredoxin AB285_22565 ENOG4105ESV Glycosyl transferase, family 4 AB285_22570 ENOG4105SFE lipopolysaccharide biosynthesis protein AB285_22575 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AB285_22580 ENOG4108IJ1 Dehydrogenase AB285_22585 ENOG4108WJ1 acetyltransferase AB285_22590 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AB285_22595 ENOG4105EGZ biosynthesis protein AB285_22600 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) AB285_22605 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) AB285_22610 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family AB285_22615 ENOG4105C85 amino acid AB285_22640 ENOG410601J HemY protein AB285_22645 ENOG4105ECF c-methyltransferase AB285_22650 ENOG41076E6 Uroporphyrinogen-III Synthase AB285_22655 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) AB285_22660 ENOG4107T0K Adenylate cyclase AB285_22665 ENOG4105XQ6 frataxin-like protein AB285_22670 ENOG4105S7Z (LipO)protein AB285_22680 ENOG4105CT0 Protein of unknown function, DUF484 AB285_22685 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB285_22690 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant AB285_22695 ENOG4105C4R Atp-dependent dna helicase AB285_22705 ENOG4105FR1 rard protein AB285_22710 ENOG4108VUY thioesterase Superfamily protein AB285_22715 ENOG4105HDD phospholipase AB285_22720 ENOG4105C9U ATP-dependent DNA helicase RecQ AB285_22730 ENOG410829K Lysine exporter protein (Lyse ygga) AB285_22735 ENOG4108EUD Lysophospholipase AB285_22740 ENOG4105DQF Hydrolase AB285_22745 ENOG4105EMK carboxylate amino acid amine transporter AB285_22750 ENOG4105DZ2 Transcriptional regulator AB285_22760 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) AB285_22765 ENOG4108I5U Uridine phosphorylase AB285_22770 ENOG4105CGY Dna recombination protein AB285_22775 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB285_22780 ENOG4105JC1 sterol-binding domain protein AB285_22785 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) AB285_22790 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AB285_22800 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AB285_22805 ENOG4105F8V Hydrolase, tatD family AB285_22810 ENOG4105MDZ Transcriptional activator rfaH AB285_22815 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AB285_22820 ENOG4107QK7 reductase AB285_22825 ENOG4105C5H ABC transporter AB285_22830 ENOG4105MVF Transcriptional regulator AB285_22840 ENOG4106JH6 (LipO)protein AB285_22845 ENOG4105VEQ Cold shock protein AB285_22850 ENOG4105C5I Dehydrogenase AB285_22860 ENOG4105D7K pfkb domain protein AB285_22870 ENOG4108M60 Transcriptional regulator AB285_22875 ENOG4108ZG0 Ompa motb domain protein AB285_22880 ENOG4107QY8 reductase AB285_22885 ENOG4105HNP -acetyltransferase AB285_22890 ENOG4108R3E Dna-3-methyladenine glycosylase i AB285_22900 ENOG4105FCD Major Facilitator AB285_22905 ENOG4105DIJ Phosphoethanolamine transferase AB285_22915 ENOG4105DEF Extracellular solute-binding protein, family 5 AB285_22920 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AB285_22925 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB285_22930 ENOG4105C3U ABC transporter AB285_22935 ENOG4108JQ7 (ABC) transporter AB285_22940 ENOG4105CS9 pantothenic acid kinase AB285_22965 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AB285_22970 ENOG4105PM1 preprotein translocase subunit SecE AB285_22975 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AB285_23000 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AB285_23020 ENOG4106TD9 Diguanylate cyclase AB285_23025 ENOG4105D41 biosynthesis protein thiH AB285_23030 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) AB285_23035 ENOG4105WHD thiamine biosynthesis protein ThiS AB285_23040 ENOG4105D06 uba thif-type nad fad binding protein AB285_23045 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) AB285_23050 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) AB285_23055 ENOG4107MNS Has binding activity to the major sigma subunit of RNA polymerase. May be involved in replacement of the RNA polymerase sigma subunit from sigma-70 to sigma-S during the transition from exponential growth to the stationary phase (By similarity) AB285_23065 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) AB285_23070 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) AB285_23075 ENOG4105R2J Conserved Protein AB285_23080 ENOG4105K70 DNA-binding protein AB285_23085 ENOG4108T8B Protein of unknown function (DUF1481) AB285_23090 ENOG4105C12 Phosphoribosylglycinamide synthetase AB285_23115 ENOG4105CVG Homoserine O-transsuccinylase AB285_23120 ENOG4107QP3 malate synthase g AB285_23125 ENOG4108I9X Isocitrate lyase AB285_23130 ENOG4105VS7 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) AB285_23135 ENOG41069M3 Transcriptional regulator AB285_23140 ENOG4105C3R Methionine synthase AB285_23145 ENOG4105EAM Na Pi-cotransporter AB285_23160 ENOG4105FE9 pseudouridine synthase AB285_23165 ENOG4108ZR5 Conserved Protein AB285_23170 ENOG4105C09 Bile acid AB285_23175 ENOG4105CFH Aspartokinase AB285_23190 ENOG4108MDC (LipO)protein AB285_23195 ENOG4108Q9C Periplasmic Protein AB285_23200 ENOG4105E3R (LipO)protein AB285_23205 ENOG4108VY7 phosphate-starvation-inducible protein PsiE AB285_23210 ENOG4105EG2 ABC transporter, permease AB285_23215 ENOG4105D56 permease protein AB285_23220 ENOG4107FKK extracellular solute-binding protein family 1 AB285_23230 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) AB285_23235 ENOG4107W52 maltose operon periplasmic protein AB285_23250 ENOG4105VEI Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity) AB285_23255 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) AB285_23260 ENOG4105E55 glycerol-3-phosphate acyltransferase AB285_23265 ENOG41080IJ Diacylglycerol kinase AB285_23270 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) AB285_23275 ENOG4107R73 Mate efflux family protein AB285_23280 ENOG4105VDW Csbd family AB285_23285 ENOG4105MYN Zinc uptake regulation protein AB285_23325 ENOG4105CEC DNA methylase N-4 N-6 AB285_23340 ENOG4108R7K Metal Dependent Phosphohydrolase AB285_23345 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) AB285_23350 ENOG4105H40 AB285_23360 ENOG4105RDA repressor AB285_23365 ENOG41078CG DNA-binding transcriptional regulator AB285_23370 ENOG4108S1U AB285_23385 ENOG4105CAR Terminase, large subunit AB285_23400 ENOG4108MXB Protein of unknown function (DUF968) AB285_23475 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AB285_23560 ENOG4108C33 Resolvase AB285_23570 ENOG4106FE3 DNA repair AB285_23580 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AB285_23585 ENOG4105P4Z Phage shock protein G AB285_23590 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AB285_23595 ENOG4105CDU Replicative dna helicase AB285_23600 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AB285_23605 ENOG4105CGF Aromatic amino acid aminotransferase AB285_23610 ENOG4105F0S class B acid phosphatase AB285_23615 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme AB285_23620 ENOG4105MSB protein, conserved in bacteria AB285_23625 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AB285_23630 ENOG4108UUM single-stranded DNA-binding protein AB285_23635 ENOG4105PMV Membrane AB285_23645 ENOG4108M8H domain protein AB285_23650 ENOG4108W3Q Transcriptional regulator AB285_23655 ENOG4108Z4X TRANSCRIPTIONal AB285_23660 ENOG4108K3A Glutathione S-transferase AB285_23665 ENOG4105C7N Xanthine uracil vitamin C permease AB285_23670 ENOG4105EEQ Na H antiporter AB285_23675 ENOG4105CMU LysR family (Transcriptional regulator AB285_23680 ENOG4105VAW lrga family AB285_23685 ENOG41067MG lrgb family AB285_23690 ENOG4107QN1 sodium solute AB285_23695 ENOG41062QD Membrane AB285_23700 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AB285_23705 ENOG4105CK2 sodium dicarboxylate symporter AB285_23710 ENOG41082ND Uncharacterized protein yjcO AB285_23715 ENOG41074AV Hok/gef family AB285_23720 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB285_23725 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB285_23730 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AB285_23740 ENOG4105D2N Aldolase AB285_23750 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AB285_23755 ENOG4105CNN ABC, transporter AB285_23760 ENOG4105C2J ABC transporter AB285_23765 ENOG4105BZU Histidine kinase AB285_23770 ENOG4107TFG D-allose kinase AB285_23775 ENOG4105UP7 3-epimerase AB285_23780 ENOG4105CNN ABC, transporter AB285_23785 ENOG4105C2J ABC transporter AB285_23790 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AB285_23795 ENOG4105NYY transcriptional regulator, RpiR AB285_23800 ENOG4108YZG isomerase AB285_23810 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein AB285_23815 ENOG410849A acetyltransferase, (GNAT) family AB285_23820 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) AB285_23825 ENOG4105FD8 phosphonate metabolism protein PhnM AB285_23830 ENOG4105HRV phosphonate c-p lyase system protein phnl AB285_23835 ENOG4105ENV phosphonate C-P lyase system protein PhnK AB285_23840 ENOG4105FT8 Phosphonate metabolism AB285_23845 ENOG4105EKV Phosphonate metabolism protein AB285_23850 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH