locus-tag	class	description
A6P53_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A6P53_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A6P53_00015	ENOG410848D	S4 domain protein YaaA
A6P53_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A6P53_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6P53_00035	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A6P53_00040	ENOG4108UUM	single-stranded DNA-binding protein
A6P53_00045	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A6P53_00060	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A6P53_00070	ENOG4105CDU	Replicative dna helicase
A6P53_00075	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A6P53_00085	ENOG4105C5H	ABC transporter
A6P53_00095	ENOG4105C7K	acetolactate synthase
A6P53_00130	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6P53_00135	ENOG4105CS9	pantothenic acid kinase
A6P53_00140	ENOG4107Y49	methyltransferase
A6P53_00150	ENOG4105ETE	Transcriptional regulator (LacI family
A6P53_00155	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A6P53_00160	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A6P53_00165	ENOG4105KG3	cytidine deaminase
A6P53_00170	ENOG4105DIH	basic membrane
A6P53_00175	ENOG4108JQ9	ABC transporter
A6P53_00180	ENOG4105UIB	(ABC) transporter
A6P53_00190	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
A6P53_00200	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A6P53_00205	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A6P53_00215	ENOG4105E66	phosphoriboisomerase A
A6P53_00220	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A6P53_00225	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A6P53_00230	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A6P53_00235	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6P53_00245	ENOG4105CI1	PTS System
A6P53_00255	ENOG4105DM4	PTS System
A6P53_00260	ENOG4108YRF	PTS System
A6P53_00265	ENOG4105DM4	PTS System
A6P53_00280	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A6P53_00285	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A6P53_00290	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A6P53_00295	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A6P53_00300	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A6P53_00305	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A6P53_00310	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A6P53_00315	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A6P53_00320	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A6P53_00325	ENOG41082SA	50s ribosomal protein l29
A6P53_00330	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A6P53_00335	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A6P53_00340	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A6P53_00345	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A6P53_00350	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A6P53_00355	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A6P53_00360	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A6P53_00365	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A6P53_00370	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A6P53_00375	ENOG4105VPB	50S ribosomal protein L30
A6P53_00380	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A6P53_00385	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A6P53_00390	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A6P53_00395	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A6P53_00400	ENOG41067V7	50S ribosomal protein L36
A6P53_00405	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A6P53_00410	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A6P53_00415	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6P53_00420	ENOG4108ZT0	50S ribosomal protein l17
A6P53_00425	ENOG4108JJB	ABC transporter
A6P53_00430	ENOG4108JJB	ABC transporter
A6P53_00440	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A6P53_00470	ENOG4105VB9	50S ribosomal protein l28
A6P53_00480	ENOG4105DP4	dak2 domain fusion protein ylov
A6P53_00485	ENOG4105CB5	ATP-dependent DNA helicase recG
A6P53_00490	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A6P53_00495	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A6P53_00505	ENOG4108JQ7	(ABC) transporter
A6P53_00510	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A6P53_00525	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A6P53_00530	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A6P53_00535	ENOG410667J	hydrolase
A6P53_00540	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A6P53_00550	ENOG4105D9M	gamma-glutamylcysteine synthetase
A6P53_00580	ENOG4105DHS	permease protein
A6P53_00585	ENOG4105CM4	permease protein
A6P53_00590	ENOG4108IPW	abc transporter atp-binding protein
A6P53_00610	ENOG41068WN	
A6P53_00635	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A6P53_00640	ENOG4105VAW	lrga family
A6P53_00645	ENOG41067MG	lrgb family
A6P53_00660	ENOG4105CHR	reductase
A6P53_00665	ENOG410807C	QueT transporter
A6P53_00695	ENOG4105VKD	bioY protein
A6P53_00700	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A6P53_00715	ENOG4105D48	metallophosphoesterase
A6P53_00725	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A6P53_00740	ENOG4105C5Y	PTS System
A6P53_00745	ENOG4107414	GntR family transcriptional regulator
A6P53_00750	ENOG4105E0X	reductase
A6P53_00755	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A6P53_00760	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A6P53_00770	ENOG4105KJF	protein tyrosine phosphatase
A6P53_00785	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A6P53_00790	ENOG4105C85	amino acid
A6P53_00795	ENOG4105CDA	abc transporter atp-binding protein
A6P53_00800	ENOG4105E5Q	amino acid AbC transporter
A6P53_00810	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A6P53_00815	ENOG4108UW5	maltose o-acetyltransferase
A6P53_00840	ENOG4107YB9	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A6P53_00845	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A6P53_00850	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A6P53_00860	ENOG4105DFH	Transport of potassium into the cell (By similarity)
A6P53_00870	ENOG4105C37	(CBS) domain
A6P53_00890	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A6P53_00895	ENOG4105I08	Pseudouridine synthase
A6P53_00905	ENOG4105DBI	uridine monophosphokinase
A6P53_00925	ENOG4107XJU	UPF0178 protein
A6P53_00940	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
A6P53_00945	ENOG4105C1J	atp-dependent rna helicase
A6P53_00950	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A6P53_00955	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A6P53_00960	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
A6P53_00965	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A6P53_00970	ENOG4105DQ4	alcohol dehydrogenase
A6P53_00980	ENOG4105C0X	amino acid
A6P53_00990	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A6P53_01015	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
A6P53_01030	ENOG4105CPK	Glycosyl transferase (Group 1
A6P53_01080	ENOG4105D3Q	Sugar transferase
A6P53_01085	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A6P53_01105	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A6P53_01115	ENOG4108EKI	Dehydrogenase
A6P53_01125	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A6P53_01140	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A6P53_01145	ENOG4105ZMH	deoxynucleoside kinase
A6P53_01155	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A6P53_01160	ENOG4105VJV	50s ribosomal protein L35
A6P53_01165	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A6P53_01185	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A6P53_01220	ENOG4105VDH	Dihydroxyacetone kinase
A6P53_01225	ENOG4105CMT	Dihydroxyacetone kinase
A6P53_01230	ENOG4108UTZ	Dihydroxyacetone kinase
A6P53_01245	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
A6P53_01250	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A6P53_01260	ENOG4105E5D	amino acid
A6P53_01265	ENOG4105DFD	Na H antiporter
A6P53_01270	ENOG4105ETE	Transcriptional regulator (LacI family
A6P53_01280	ENOG4107URF	beta-phospho-glucomutase
A6P53_01290	ENOG4105CI1	PTS System
A6P53_01310	ENOG4105PY6	Phenolic acid decarboxylase
A6P53_01315	ENOG4105U3E	Transcriptional regulator
A6P53_01340	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A6P53_01350	ENOG4105BZU	Histidine kinase
A6P53_01385	ENOG4105C19	ABC transporter
A6P53_01395	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
A6P53_01400	ENOG4105ETE	Transcriptional regulator (LacI family
A6P53_01420	ENOG4105CG3	alpha amylase, catalytic region
A6P53_01445	ENOG4105DSE	periplasmic solute binding protein
A6P53_01450	ENOG4108WCX	response regulator
A6P53_01475	ENOG4105ENA	helicase
A6P53_01480	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
A6P53_01485	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
A6P53_01505	ENOG4108V06	Glutathione peroxidase
A6P53_01515	ENOG4105C28	cystathionine
A6P53_01520	ENOG4105C6T	cysteine synthase
A6P53_01525	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6P53_01555	ENOG4108UT2	hemolysin iii
A6P53_01560	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A6P53_01565	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A6P53_01570	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A6P53_01575	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A6P53_01580	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A6P53_01585	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A6P53_01590	ENOG4105CFH	Aspartokinase
A6P53_01595	ENOG4105CH2	amidohydrolase
A6P53_01600	ENOG4105CHM	Aminotransferase
A6P53_01605	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A6P53_01610	ENOG4105FTV	AraC Family Transcriptional Regulator
A6P53_01620	ENOG4105CT4	transporter
A6P53_01650	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A6P53_01665	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
A6P53_01670	ENOG4105D49	3-dehydroquinate synthase
A6P53_01675	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A6P53_01680	ENOG4105EVN	Prephenate dehydrogenase
A6P53_01690	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A6P53_01695	ENOG4105CQC	Prephenate dehydratase
A6P53_01700	ENOG4108Z0Z	intracellular protease Pfpi family
A6P53_01715	ENOG4105MIX	Adenylate cyclase
A6P53_01725	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A6P53_01730	ENOG4105EMS	pseudouridine synthase
A6P53_01735	ENOG4105CJW	magnesium transporter
A6P53_01740	ENOG4106N3A	copper homeostasis protein cutc
A6P53_01750	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A6P53_01755	ENOG4107TB6	phosphoglycerate mutase
A6P53_01760	ENOG4105C7H	Helicase, RecD TraA family
A6P53_01765	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
A6P53_01780	ENOG4107FTN	50S ribosomal protein L33
A6P53_01790	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A6P53_01815	ENOG4105EJQ	L-serine dehydratase
A6P53_01825	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A6P53_01830	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A6P53_01835	ENOG4108VZM	50s ribosomal protein L10
A6P53_01840	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A6P53_01860	ENOG4105EQ0	Major Facilitator superfamily
A6P53_01870	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
A6P53_01875	ENOG4105C5H	ABC transporter
A6P53_01880	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A6P53_01885	ENOG4105KT7	mgtC SapB transporter
A6P53_01890	ENOG4105C02	permease
A6P53_01905	ENOG4108YRF	PTS System
A6P53_01910	ENOG41064BA	PTS system, fructose-specific, IIA component
A6P53_01915	ENOG4108YRF	PTS System
A6P53_01920	ENOG4105DM4	PTS System
A6P53_01925	ENOG4105UP7	3-epimerase
A6P53_01935	ENOG4107W7X	Aldolase
A6P53_01945	ENOG4105DET	Rhamnulokinase
A6P53_01965	ENOG4105ETZ	PTS System
A6P53_01975	ENOG4108SU4	UPF0309 protein
A6P53_01985	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6P53_01990	ENOG41067VN	Glutaredoxin
A6P53_02010	ENOG4108IJ7	Glycine betaine
A6P53_02020	ENOG4108RAV	Conserved protein
A6P53_02040	ENOG4105EPR	degv family
A6P53_02050	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6P53_02055	ENOG4105BZU	Histidine kinase
A6P53_02070	ENOG4105Q2H	domain protein
A6P53_02090	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A6P53_02095	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A6P53_02115	ENOG4107TXC	Transcriptional regulator
A6P53_02135	ENOG4105DAP	Nicotinate phosphoribosyltransferase
A6P53_02140	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
A6P53_02145	ENOG4107T7U	Sulfatase
A6P53_02155	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A6P53_02170	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A6P53_02185	ENOG4105BZ1	(ABC) transporter
A6P53_02200	ENOG4105DG6	mannose-6-phosphate isomerase
A6P53_02210	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
A6P53_02215	ENOG4105EV1	Ribose uptake protein RbsU
A6P53_02275	ENOG4105F1K	Glutamine amidotransferase
A6P53_02280	ENOG4105DMS	mur ligase
A6P53_02285	ENOG4105WT3	Transcriptional regulator
A6P53_02315	ENOG4105C3F	Signal peptidase i
A6P53_02325	ENOG4107104	thymidine kinase
A6P53_02330	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A6P53_02335	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A6P53_02340	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6P53_02345	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A6P53_02350	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
A6P53_02355	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A6P53_02380	ENOG4105CKK	Glycosyl transferase, family 2
A6P53_02385	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A6P53_02390	ENOG4105HMI	Membrane
A6P53_02410	ENOG41080E8	Transcriptional regulator, Spx MgsR family
A6P53_02415	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A6P53_02420	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A6P53_02425	ENOG4108UMI	ABC transporter, permease
A6P53_02430	ENOG4105D01	(LipO)protein
A6P53_02440	ENOG4105JRK	feS assembly protein SufD
A6P53_02445	ENOG4105C9B	Cysteine desulfurase
A6P53_02450	ENOG4108UNV	SUF system FeS assembly protein, NifU family
A6P53_02455	ENOG4105DIW	FeS assembly protein SUFB
A6P53_02485	ENOG4108UXE	Protein tyrosine phosphatase
A6P53_02515	ENOG4108X79	transcriptional regulator
A6P53_02520	ENOG4105E70	isomerase
A6P53_02525	ENOG4105D2M	Aldolase
A6P53_02530	ENOG4105DE4	1-phosphofructokinase
A6P53_02545	ENOG4108EQA	pts system
A6P53_02550	ENOG4105ETZ	PTS System
A6P53_02555	ENOG4105F3R	pts system mannose fructose sorbose family iid
A6P53_02570	ENOG4105WH1	Two component transcriptional regulator luxr family
A6P53_02580	ENOG4105DBV	ornithine carbamoyltransferase
A6P53_02585	ENOG410839U	amino acid
A6P53_02590	ENOG4105DWY	Agmatine deiminase
A6P53_02600	ENOG4105C19	ABC transporter
A6P53_02605	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A6P53_02615	ENOG4108YG4	
A6P53_02620	ENOG4106ZEE	Diacylglycerol kinase
A6P53_02625	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
A6P53_02630	ENOG4107RGD	Major Facilitator superfamily
A6P53_02640	ENOG4108Z6X	(sortase) family
A6P53_02645	ENOG4105CID	antiterminator
A6P53_02650	ENOG4105C5Y	PTS System
A6P53_02655	ENOG4105CS2	ec 3.2.1.21
A6P53_02660	ENOG4105TMB	Formate nitrite transporter
A6P53_02665	ENOG4105FDP	GntR family transcriptional regulator
A6P53_02670	ENOG4105CK1	PTS System
A6P53_02680	ENOG41069H0	dihydroorotase EC 3.5.2.3
A6P53_02700	ENOG4108URH	decarboxylase
A6P53_02710	ENOG4105ZMH	deoxynucleoside kinase
A6P53_02725	ENOG4105CS2	ec 3.2.1.21
A6P53_02730	ENOG4108IJ9	(ABC) transporter
A6P53_02740	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A6P53_02755	ENOG4105CGH	5'-nucleotidase
A6P53_02770	ENOG4105E0M	Sulfatase
A6P53_02780	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A6P53_02785	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A6P53_02790	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A6P53_02795	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A6P53_02800	ENOG4108UMI	ABC transporter, permease
A6P53_02805	ENOG4105D01	(LipO)protein
A6P53_02810	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
A6P53_02815	ENOG4105DFD	Na H antiporter
A6P53_02840	ENOG4105BZU	Histidine kinase
A6P53_02845	ENOG4105E5D	amino acid
A6P53_02860	ENOG4105BZW	Glycerate kinase
A6P53_02865	ENOG4105C5H	ABC transporter
A6P53_02880	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A6P53_02885	ENOG4105C5Y	PTS System
A6P53_02900	ENOG4105D5Q	Arginine ornithine antiporter
A6P53_02905	ENOG4105KPY	Small multidrug resistance protein
A6P53_02920	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A6P53_02935	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A6P53_02970	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A6P53_02975	ENOG4108IJ2	phosphate acetyltransferase
A6P53_02980	ENOG4105K8N	protein family UPF0079, ATPase
A6P53_02985	ENOG4108MK9	spermidine N(1)-acetyltransferase
A6P53_02995	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A6P53_03000	ENOG4105CGK	Exodeoxyribonuclease III
A6P53_03005	ENOG4105EP9	oxidoreductase
A6P53_03010	ENOG4105D4A	Cell wall formation (By similarity)
A6P53_03015	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A6P53_03035	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
A6P53_03050	ENOG4105FH5	Membrane
A6P53_03055	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A6P53_03065	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
A6P53_03075	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6P53_03080	ENOG4105F38	ABC transporter, permease
A6P53_03085	ENOG4105D38	putrescine abc transporter
A6P53_03090	ENOG4107RUE	extracellular solute-binding protein family 1
A6P53_03110	ENOG4105FS7	Transcriptional regulator
A6P53_03115	ENOG4105BZ1	(ABC) transporter
A6P53_03120	ENOG4105US7	Histidine kinase
A6P53_03125	ENOG4108STX	response regulator
A6P53_03130	ENOG4107WD8	ABC transporter, permease
A6P53_03145	ENOG4105C5H	ABC transporter
A6P53_03150	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
A6P53_03160	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
A6P53_03165	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
A6P53_03170	ENOG4105C19	ABC transporter
A6P53_03185	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
A6P53_03190	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
A6P53_03195	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
A6P53_03200	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
A6P53_03205	ENOG4105CN9	Peptidase m42 family protein
A6P53_03215	ENOG4108RQ5	Beta-lactamase domain-containing protein
A6P53_03220	ENOG4105DF9	Lipoate-protein, ligase
A6P53_03245	ENOG4105KA3	membrAne
A6P53_03250	ENOG4105CHH	sulfate transporter
A6P53_03260	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A6P53_03270	ENOG4105K46	50S ribosomal protein l27
A6P53_03275	ENOG4108TGC	Acyltransferase
A6P53_03280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6P53_03285	ENOG4108EQA	pts system
A6P53_03295	ENOG4105ETZ	PTS System
A6P53_03300	ENOG4105F3R	pts system mannose fructose sorbose family iid
A6P53_03310	ENOG4107BMA	Transglycosylase associated protein
A6P53_03315	ENOG4105DC7	peptidase M24
A6P53_03320	ENOG4108ZSR	alkaline shock protein
A6P53_03325	ENOG4105M7K	Involved in the transcription termination process (By similarity)
A6P53_03330	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A6P53_03335	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6P53_03340	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6P53_03345	ENOG4105CTB	Polyprenyl synthetase
A6P53_03350	ENOG4105DX0	Hemolysin A
A6P53_03355	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
A6P53_03360	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A6P53_03385	ENOG41068DC	Essential cell division protein (By similarity)
A6P53_03390	ENOG4105CJN	penicillin-binding protein
A6P53_03425	ENOG4105DFA	alanine racemase domain protein
A6P53_03430	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
A6P53_03435	ENOG41067XK	integral membrane protein
A6P53_03440	ENOG4105DBK	s4 domain protein
A6P53_03445	ENOG4105MMF	Cell division protein DIVIVA
A6P53_03450	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A6P53_03470	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A6P53_03475	ENOG4107RPQ	ABC transporter
A6P53_03490	ENOG4105EE0	oxidoreductase
A6P53_03500	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6P53_03505	ENOG4105VZJ	PTS System
A6P53_03515	ENOG4105CK1	PTS System
A6P53_03550	ENOG4105C88	aminopeptidase
A6P53_03560	ENOG4105NQC	Flavodoxin
A6P53_03570	ENOG4107U9T	Pfam:Ribonuclease_BN
A6P53_03575	ENOG4105ESV	Glycosyl transferase, family 4
A6P53_03590	ENOG4108SHN	Glycosyl transferase, family 2
A6P53_03595	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A6P53_03600	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A6P53_03605	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A6P53_03610	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A6P53_03640	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A6P53_03655	ENOG4105K64	Glycosyl transferase, family 2
A6P53_03660	ENOG4105KPE	licD family
A6P53_03675	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A6P53_03680	ENOG4105K64	Glycosyl transferase, family 2
A6P53_03690	ENOG4105KPE	licD family
A6P53_03710	ENOG4107R6D	beta-lactam binding protein AmpH
A6P53_03720	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A6P53_03730	ENOG4105ENE	Histidine kinase
A6P53_03740	ENOG4107ZYR	domain protein
A6P53_03745	ENOG4105W8X	HesB YadR YfhF-family protein
A6P53_03760	ENOG4105WH5	Teichoic acid glycosylation protein
A6P53_03765	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A6P53_03770	ENOG4105VEQ	Cold shock protein
A6P53_03800	ENOG4108KGH	TRANSCRIPTIONal
A6P53_03805	ENOG4105KAV	tspo and mbr like protein
A6P53_03815	ENOG4108M1A	Chitin-binding protein
A6P53_03825	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A6P53_03830	ENOG410902V	Modulates RecA activity (By similarity)
A6P53_03835	ENOG4105CEN	a g-specific adenine glycosylase
A6P53_03840	ENOG4105EVI	UPF0374 protein
A6P53_03850	ENOG4105C02	permease
A6P53_03860	ENOG4106AM8	polysaccharide lyase family 8
A6P53_03865	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A6P53_03870	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A6P53_03880	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6P53_03885	ENOG4105KRI	phosphocarrier protein (HPr
A6P53_03890	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A6P53_03895	ENOG4105W2C	Glycosyl transferase
A6P53_03900	ENOG4105BZF	Glycosyl transferase (Group 1
A6P53_03905	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A6P53_03910	ENOG4107IN1	Protein of unknown function (DUF1797)
A6P53_03915	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A6P53_03925	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A6P53_03935	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A6P53_03940	ENOG4105CHR	reductase
A6P53_03945	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6P53_03955	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A6P53_03960	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A6P53_03965	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A6P53_03970	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A6P53_03980	ENOG4106PMH	Extracellular solute-binding protein family 3
A6P53_03985	ENOG4105E5Q	amino acid AbC transporter
A6P53_03990	ENOG4105CDA	abc transporter atp-binding protein
A6P53_04000	ENOG4105CQW	ribosome biogenesis GTPase YqeH
A6P53_04005	ENOG410812S	Rna-binding protein
A6P53_04010	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A6P53_04015	ENOG4108WF2	Metal Dependent Phosphohydrolase
A6P53_04025	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A6P53_04030	ENOG4105CDE	UPF0348 protein
A6P53_04035	ENOG4105CDY	transcriptional regulatory protein
A6P53_04045	ENOG4105EEM	helicase
A6P53_04055	ENOG41069HH	4-oxalocrotonate tautomerase
A6P53_04060	ENOG4105C22	threonyL-tRNA synthetase
A6P53_04075	ENOG4107RF6	penicillin-binding protein
A6P53_04080	ENOG4108KP7	hydrolase
A6P53_04085	ENOG4105C7N	Xanthine uracil vitamin C permease
A6P53_04090	ENOG4105C6X	Major Facilitator
A6P53_04100	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6P53_04105	ENOG4105CTQ	phosphohexokinase
A6P53_04110	ENOG4105CA9	Pyruvate kinase
A6P53_04115	ENOG4107ZGM	malolactic fermentation system
A6P53_04125	ENOG41067VY	50S ribosomal protein L32
A6P53_04130	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A6P53_04135	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6P53_04140	ENOG4105GR3	Histidine kinase
A6P53_04245	ENOG4105T9C	HD domain
A6P53_04250	ENOG4105ETU	transcriptional activator (TenA
A6P53_04260	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
A6P53_04265	ENOG4105DWF	phosphomethylpyrimidine kinase
A6P53_04270	ENOG4105DKT	Transcriptional regulator
A6P53_04275	ENOG410787A	Pts system, glucitol sorbitol-specific
A6P53_04280	ENOG4105DZY	Pts system, glucitol sorbitol-specific
A6P53_04285	ENOG4105CPQ	Dehydrogenase
A6P53_04290	ENOG4105C5I	Dehydrogenase
A6P53_04330	ENOG4108TZY	GntR Family Transcriptional Regulator
A6P53_04335	ENOG4105CK1	PTS System
A6P53_04340	ENOG4105CS2	ec 3.2.1.21
A6P53_04365	ENOG4107YZX	Universal stress protein
A6P53_04370	ENOG4105DWF	phosphomethylpyrimidine kinase
A6P53_04380	ENOG4105DE4	1-phosphofructokinase
A6P53_04385	ENOG4105DM4	PTS System
A6P53_04395	ENOG4105D2M	Aldolase
A6P53_04430	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A6P53_04445	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
A6P53_04465	ENOG410841Q	phosphoesterase PA-phosphatase related protein
A6P53_04490	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
A6P53_04500	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6P53_04515	ENOG41065S2	pneumococcal vaccine antigen
A6P53_04525	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A6P53_04530	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A6P53_04535	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6P53_04540	ENOG41070VT	
A6P53_04545	ENOG4105QNR	S1 RNA binding domain protein
A6P53_04550	ENOG4105I3K	Ferric uptake regulator, Fur family
A6P53_04555	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6P53_04565	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A6P53_04570	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A6P53_04575	ENOG4105FE9	pseudouridine synthase
A6P53_04580	ENOG4108SAX	Membrane
A6P53_04585	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A6P53_04590	ENOG4107QSE	Dipeptidase
A6P53_04610	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6P53_04615	ENOG41068JE	domain protein
A6P53_04620	ENOG4105CAT	Cytidine monophosphate kinase
A6P53_04625	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A6P53_04630	ENOG4105EVU	fructokinase
A6P53_04635	ENOG4105C5Y	PTS System
A6P53_04645	ENOG4105ETE	Transcriptional regulator (LacI family
A6P53_04650	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A6P53_04655	ENOG4105K70	DNA-binding protein
A6P53_04670	ENOG41068YB	TPR repeat-containing protein
A6P53_04675	ENOG4108SXZ	UPF0302 protein
A6P53_04680	ENOG4108JYZ	YitT family
A6P53_04685	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
A6P53_04690	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A6P53_04705	ENOG4107SUZ	Sodium/hydrogen exchanger family
A6P53_04715	ENOG4105KPY	Small multidrug resistance protein
A6P53_04720	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
A6P53_04725	ENOG4105C5H	ABC transporter
A6P53_04730	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A6P53_04740	ENOG4108RCR	degv family
A6P53_04745	ENOG41090WU	lipolytic protein G-D-S-L family
A6P53_04750	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
A6P53_04760	ENOG4105VSD	UPF0346 protein
A6P53_04770	ENOG4105DF9	Lipoate-protein, ligase
A6P53_04790	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A6P53_04795	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6P53_04800	ENOG4105C79	DNA protecting protein DprA
A6P53_04805	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A6P53_04810	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
A6P53_04815	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6P53_04820	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A6P53_04825	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A6P53_04830	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
A6P53_04840	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A6P53_04845	ENOG4105K4P	CoA-binding domain protein
A6P53_04850	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6P53_04860	ENOG4105C6N	Formate acetyltransferase
A6P53_04865	ENOG4105F1A	Pyruvate formate-lyase
A6P53_04875	ENOG4105E98	transcriptional regulator DeoR family
A6P53_04880	ENOG41075H3	AraC family transcriptional regulator
A6P53_04915	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A6P53_04925	ENOG4105CS2	ec 3.2.1.21
A6P53_04930	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A6P53_04955	ENOG4105FKQ	transcriptional regulator
A6P53_04965	ENOG4105CIS	alcohol dehydrogenase
A6P53_04970	ENOG4108JYZ	YitT family
A6P53_04980	ENOG4108HQR	Glycine betaine
A6P53_04985	ENOG4108IJ8	ABC transporter
A6P53_05020	ENOG4106PHI	plasmid recombination enzyme
A6P53_05025	ENOG4105VRS	hydrolase family 18
A6P53_05040	ENOG4105CHM	Aminotransferase
A6P53_05050	ENOG4105CE4	GlcNAc 6-P deacetylase
A6P53_05070	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
A6P53_05085	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
A6P53_05095	ENOG4105VUF	Transcriptional regulator
A6P53_05110	ENOG4105DZ6	Band 7 protein
A6P53_05120	ENOG4108QEG	Membrane
A6P53_05135	ENOG4108VXD	carboxy-peptidase
A6P53_05140	ENOG4107X35	defense response to bacterium
A6P53_05150	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
A6P53_05155	ENOG4105C2W	permease
A6P53_05170	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A6P53_05175	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A6P53_05180	ENOG4105C83	adenylosuccinate lyase
A6P53_05190	ENOG4105C8V	SAICAR synthetase
A6P53_05195	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
A6P53_05200	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A6P53_05205	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
A6P53_05210	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A6P53_05215	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A6P53_05220	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A6P53_05225	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A6P53_05230	ENOG4105C12	Phosphoribosylglycinamide synthetase
A6P53_05235	ENOG4107QM2	Aldo Keto reductase
A6P53_05245	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
A6P53_05260	ENOG4105CPP	Dehydrogenase, E1 component
A6P53_05265	ENOG4105C7S	Dehydrogenase
A6P53_05315	ENOG4105WBI	UPF0223 protein
A6P53_05320	ENOG4105ECY	inositol monophosphatase
A6P53_05325	ENOG4105CI3	gtp-binding protein typa
A6P53_05330	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6P53_05335	ENOG4105ZPI	UPF0358 protein
A6P53_05340	ENOG4105CNI	cell division protein FtsW
A6P53_05345	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A6P53_05360	ENOG4105WUC	UPF0298 protein
A6P53_05365	ENOG4106H78	methyltransferase
A6P53_05370	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A6P53_05375	ENOG41063PX	domain protein
A6P53_05390	ENOG4108UK2	deaminase
A6P53_05395	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
A6P53_05400	ENOG4105TQK	DNA polymerase iii, delta' subunit
A6P53_05405	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A6P53_05415	ENOG4108VMM	UPF0756 membrane protein
A6P53_05420	ENOG4105C59	p-type ATPase
A6P53_05425	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A6P53_05440	ENOG4105DVT	helicase
A6P53_05440	ENOG4105DVT	helicase
A6P53_05445	ENOG4108VPT	UPF0234 protein
A6P53_05450	ENOG4107AYK	membrAne
A6P53_05455	ENOG4105VG1	fes assembly suf system protein
A6P53_05480	ENOG4105VRS	hydrolase family 18
A6P53_05555	ENOG4105DUX	Transporter
A6P53_05560	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A6P53_05565	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A6P53_05575	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A6P53_05580	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A6P53_05590	ENOG4105CDA	abc transporter atp-binding protein
A6P53_05595	ENOG4105CT1	(ABC) transporter
A6P53_05600	ENOG4105EAD	ABC transporter
A6P53_05605	ENOG4105DRP	amino acid AbC transporter
A6P53_05640	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6P53_05645	ENOG4108WBT	adenosyltransferase
A6P53_05670	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A6P53_05675	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A6P53_05690	ENOG4105D8X	mechanosensitive ion channel
A6P53_05695	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A6P53_05700	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A6P53_05705	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A6P53_05710	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6P53_05730	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A6P53_05735	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A6P53_05745	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A6P53_05750	ENOG4108IXY	short-chain dehydrogenase reductase
A6P53_05755	ENOG41067VP	Protein of unknown function (DUF1049)
A6P53_05760	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A6P53_05765	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A6P53_05775	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A6P53_05790	ENOG4107X35	defense response to bacterium
A6P53_05800	ENOG4105G5W	regulator Fur family
A6P53_05805	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A6P53_05825	ENOG4105CSM	endonuclease III
A6P53_05830	ENOG4105BZ4	penicillin-binding protein
A6P53_05835	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
A6P53_05840	ENOG4108UKS	UPF0398 protein
A6P53_05845	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
A6P53_05855	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A6P53_05860	ENOG4105CTD	carboxy-peptidase
A6P53_05870	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6P53_05875	ENOG4105EXW	epimerase dehydratase
A6P53_05880	ENOG4107R7I	amino acid
A6P53_05895	ENOG4105C1J	atp-dependent rna helicase
A6P53_05905	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A6P53_05920	ENOG4105VND	Ribonuclease
A6P53_05940	ENOG4105VEQ	Cold shock protein
A6P53_05970	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A6P53_05975	ENOG4105C34	Pseudouridine synthase
A6P53_05980	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A6P53_05990	ENOG4105CXT	aspartate transcarbamylase
A6P53_05995	ENOG4105CD3	dihydroorotase
A6P53_06000	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A6P53_06005	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A6P53_06010	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A6P53_06015	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A6P53_06020	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A6P53_06025	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A6P53_06060	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A6P53_06065	ENOG4108UMI	ABC transporter, permease
A6P53_06070	ENOG4105D01	(LipO)protein
A6P53_06075	ENOG4105F23	Fibronectin-binding protein
A6P53_06090	ENOG4105C7J	ABC transporter, permease
A6P53_06095	ENOG4105D5T	phosphonate abc transporter
A6P53_06100	ENOG4105E2X	shikimate dehydrogenase
A6P53_06105	ENOG4108RCF	TRANSCRIPTIONal
A6P53_06175	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A6P53_06190	ENOG4105D9R	oxidoreductase
A6P53_06195	ENOG4106G6Q	Transcriptional regulator
A6P53_06210	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A6P53_06220	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6P53_06225	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A6P53_06230	ENOG4105DWF	phosphomethylpyrimidine kinase
A6P53_06240	ENOG4108UIC	UPF0340 protein
A6P53_06260	ENOG4105EPR	degv family
A6P53_06305	ENOG4105D9N	nucleoside
A6P53_06310	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A6P53_06330	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A6P53_06345	ENOG4108UMI	ABC transporter, permease
A6P53_06350	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A6P53_06365	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
A6P53_06370	ENOG4105C3J	Cysteine desulfurase
A6P53_06375	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A6P53_06390	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
A6P53_06400	ENOG4105CTU	Proline racemase
A6P53_06405	ENOG41088D5	d-proline reductase
A6P53_06415	ENOG4107T4V	d-proline reductase
A6P53_06420	ENOG4107T4V	d-proline reductase
A6P53_06430	ENOG41088D5	d-proline reductase
A6P53_06435	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
A6P53_06445	ENOG4108NUI	synthase
A6P53_06450	ENOG4108VP7	maltodextrose utilization protein MalA
A6P53_06455	ENOG4105EG2	ABC transporter, permease
A6P53_06460	ENOG4105D56	permease protein
A6P53_06465	ENOG4107FKK	extracellular solute-binding protein family 1
A6P53_06470	ENOG4108IUK	alpha amylase, catalytic
A6P53_06475	ENOG4105DTQ	mandelate racemase muconate lactonizing
A6P53_06480	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
A6P53_06485	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A6P53_06490	ENOG4105E4F	Isochorismate synthase
A6P53_06495	ENOG4105CEY	Amp-dependent synthetase and ligase
A6P53_06500	ENOG4108IPT	Naphthoate synthase
A6P53_06520	ENOG4105K56	Transcriptional regulator
A6P53_06525	ENOG4106F5Q	Membrane
A6P53_06530	ENOG4107QHE	Choloylglycine hydrolase
A6P53_06545	ENOG4105D3R	alkyl hydroperoxide reductase
A6P53_06550	ENOG4108JU3	Alkyl hydroperoxide reductase
A6P53_06580	ENOG4107RVG	penicillin-binding protein
A6P53_06585	ENOG4108RCF	TRANSCRIPTIONal
A6P53_06595	ENOG4107XC4	flavin reductase domain protein, FMN-binding
A6P53_06610	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A6P53_06615	ENOG4107BMA	Transglycosylase associated protein
A6P53_06620	ENOG4105VBF	alkaline shock protein
A6P53_06640	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
A6P53_06645	ENOG4108WCX	response regulator
A6P53_06660	ENOG4105VMP	Transcriptional regulator
A6P53_06675	ENOG4105VBF	alkaline shock protein
A6P53_06690	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A6P53_06705	ENOG4105X1N	Glycosyl transferase family 8
A6P53_06710	ENOG4105X1N	Glycosyl transferase family 8
A6P53_06715	ENOG410667J	hydrolase
A6P53_06785	ENOG4105CS2	ec 3.2.1.21
A6P53_06790	ENOG4105C4W	S-formylglutathione hydrolase
A6P53_06805	ENOG4108QVC	Component IIC
A6P53_06825	ENOG4105VEQ	Cold shock protein
A6P53_06835	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A6P53_06855	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6P53_06875	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A6P53_06880	ENOG4105EGD	dinuclear metal center protein, YbgI family
A6P53_06905	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A6P53_06970	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A6P53_06975	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A6P53_06980	ENOG4105C2M	dna polymerase I
A6P53_06985	ENOG4105HFZ	Membrane
A6P53_06995	ENOG4105DFU	Cell wall formation (By similarity)
A6P53_07000	ENOG4107DB1	DUF218 domain
A6P53_07005	ENOG410906U	SprT-like
A6P53_07015	ENOG4107S1Q	Phosphatase
A6P53_07025	ENOG4105C72	UPF0176 protein
A6P53_07045	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A6P53_07050	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A6P53_07090	ENOG4105CS2	ec 3.2.1.21
A6P53_07095	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
A6P53_07100	ENOG4108QVC	Component IIC
A6P53_07105	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6P53_07140	ENOG4105EQD	regulatoR
A6P53_07145	ENOG4105C2F	Histidine kinase
A6P53_07150	ENOG4105IKJ	beta-galactosidase small subunit
A6P53_07155	ENOG4105CNT	hydrolase family 2
A6P53_07160	ENOG4105DME	alpha-galactosidase
A6P53_07175	ENOG4105BZ1	(ABC) transporter
A6P53_07180	ENOG4105BZ1	(ABC) transporter
A6P53_07205	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A6P53_07210	ENOG4105CBD	Diacylglycerol kinase
A6P53_07215	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A6P53_07220	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A6P53_07225	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A6P53_07230	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A6P53_07235	ENOG4105C4R	Atp-dependent dna helicase
A6P53_07240	ENOG4105CMQ	Chloride channel
A6P53_07265	ENOG4105DM4	PTS System
A6P53_07270	ENOG4105DE4	1-phosphofructokinase
A6P53_07275	ENOG4105E98	transcriptional regulator DeoR family
A6P53_07285	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A6P53_07290	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A6P53_07295	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A6P53_07305	ENOG4105VK3	rdd domain containing protein
A6P53_07320	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A6P53_07345	ENOG4105C8B	TIGR00159 family
A6P53_07370	ENOG4105CIE	May be required for sporulation (By similarity)
A6P53_07380	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A6P53_07395	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A6P53_07400	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A6P53_07410	ENOG4105CDA	abc transporter atp-binding protein
A6P53_07415	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A6P53_07420	ENOG4105CFG	Acts as a chaperone (By similarity)
A6P53_07425	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6P53_07430	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A6P53_07435	ENOG4105CSA	Coproporphyrinogen iii oxidase
A6P53_07500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A6P53_07505	ENOG4105NTW	Transcriptional regulator
A6P53_07515	ENOG4105E2D	ec 3.2.1.52
A6P53_07525	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6P53_07540	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A6P53_07550	ENOG4105EQD	regulatoR
A6P53_07555	ENOG4105C2F	Histidine kinase
A6P53_07600	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A6P53_07615	ENOG41090XM	Early upstream open reading frame
A6P53_07620	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A6P53_07625	ENOG4105DTN	riboflavin biosynthesis protein ribF
A6P53_07630	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A6P53_07635	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A6P53_07650	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
A6P53_07655	ENOG4105CHV	Transcription elongation factor NusA
A6P53_07660	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A6P53_07665	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A6P53_07670	ENOG4105KVH	Transcriptional regulator
A6P53_07675	ENOG4105CV8	reductase
A6P53_07680	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A6P53_07685	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A6P53_07690	ENOG4105DZP	Membrane-associated zinc metalloprotease
A6P53_07695	ENOG4105KNE	Phosphatidate cytidylyltransferase
A6P53_07700	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A6P53_07705	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A6P53_07710	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A6P53_07715	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A6P53_07720	ENOG4105CE9	30S ribosomal protein S2
A6P53_07725	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
A6P53_07730	ENOG4105C75	arginyL-tRNA synthetase
A6P53_07735	ENOG4105C5B	carbamate kinase
A6P53_07745	ENOG4105CEU	Arginine dihydrolase
A6P53_07750	ENOG4105IJJ	transcriptional regulator, crp fnr family
A6P53_07795	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6P53_07800	ENOG410801F	ribosomal-protein-alanine acetyltransferase
A6P53_07810	ENOG41072GX	Peptidase M22 Glycoprotease
A6P53_07815	ENOG4105CQ4	Transcriptional regulator
A6P53_07820	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
A6P53_07825	ENOG4105CMR	udp-glucose 4-epimerase
A6P53_07835	ENOG4105K78	MarR family Transcriptional regulator
A6P53_07845	ENOG4105WZW	rhodanese family
A6P53_07850	ENOG4105DKQ	ROK family
A6P53_07860	ENOG4107ZXI	Rhomboid family
A6P53_07865	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A6P53_07870	ENOG4105EHG	Permease protein
A6P53_07875	ENOG4105DQ5	transport system permease protein
A6P53_07880	ENOG4105E0A	ABC, transporter
A6P53_07895	ENOG4105WDJ	50S ribosomal protein L33
A6P53_07900	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
A6P53_07905	ENOG4105CAQ	asparagine synthetase
A6P53_07910	ENOG4105CKK	Glycosyl transferase, family 2
A6P53_07950	ENOG41068JE	domain protein
A6P53_07965	ENOG4107Z3H	Transcriptional regulator, TetR family
A6P53_07985	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
A6P53_08025	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
A6P53_08065	ENOG4105E4C	Lytic transglycosylase catalytic
A6P53_08200	ENOG4105PNS	DnaD domain protein
A6P53_08205	ENOG4108PNI	recT protein
A6P53_08210	ENOG4108NF7	phage-type endonuclease
A6P53_08250	ENOG4108IMY	Transcriptional regulator
A6P53_08265	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6P53_08270	ENOG4107QYV	phosphohexose isomerase
A6P53_08275	ENOG4105D82	Glutamate dehydrogenase
A6P53_08280	ENOG4105CBX	hi0933 family
A6P53_08285	ENOG4108Z66	YbaK ebsC protein
A6P53_08295	ENOG4105DR4	Methyltransferase
A6P53_08315	ENOG4105BZU	Histidine kinase
A6P53_08320	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6P53_08355	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
A6P53_08360	ENOG41067V3	Antibiotic biosynthesis monooxygenase
A6P53_08365	ENOG4108TVJ	Nitroreductase
A6P53_08370	ENOG4105FS7	Transcriptional regulator
A6P53_08445	ENOG4108ZGC	gaf domain protein
A6P53_08450	ENOG4107FQX	Alpha-acetolactate decarboxylase
A6P53_08460	ENOG4107TCE	N-acetyltransferase
A6P53_08465	ENOG4105WWK	YheO domain protein
A6P53_08475	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A6P53_08480	ENOG4105KME	endoribonuclease L-psp
A6P53_08485	ENOG4105C28	cystathionine
A6P53_08490	ENOG4105VUF	Transcriptional regulator
A6P53_08500	ENOG4105E98	transcriptional regulator DeoR family
A6P53_08510	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
A6P53_08515	ENOG4105C08	Histidine kinase
A6P53_08520	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
A6P53_08525	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A6P53_08535	ENOG4105D2M	Aldolase
A6P53_08550	ENOG4105CS2	ec 3.2.1.21
A6P53_08555	ENOG4105CK1	PTS System
A6P53_08565	ENOG4105E98	transcriptional regulator DeoR family
A6P53_08570	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A6P53_08580	ENOG4105CS2	ec 3.2.1.21
A6P53_08585	ENOG4108TZY	GntR Family Transcriptional Regulator
A6P53_08590	ENOG4105CK1	PTS System
A6P53_08595	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A6P53_08600	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A6P53_08605	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A6P53_08615	ENOG4105VB6	UPF0109 protein
A6P53_08620	ENOG4105K5M	30s ribosomal protein S16
A6P53_08630	ENOG4105DA5	(ABC) transporter
A6P53_08640	ENOG4108YYH	Nadph-dependent fmn reductase
A6P53_08650	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6P53_08655	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6P53_08660	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
A6P53_08665	ENOG4105EWC	Purine nucleoside phosphorylase
A6P53_08670	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A6P53_08675	ENOG4105BZU	Histidine kinase
A6P53_08680	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A6P53_08685	ENOG4105CVA	phosphate
A6P53_08750	ENOG4105E5D	amino acid
A6P53_08755	ENOG4105C59	p-type ATPase
A6P53_08775	ENOG4105C5S	asparaginyl-tRNA synthetase
A6P53_08780	ENOG4105CHM	Aminotransferase
A6P53_08790	ENOG4105DVT	helicase
A6P53_08815	ENOG4107R4J	Chloride channel
A6P53_08830	ENOG4108RWN	rrna methyltransferase
A6P53_08835	ENOG410855V	Acylphosphatase
A6P53_08840	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
A6P53_08850	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A6P53_08855	ENOG4108PQP	glycosyl transferase group 1
A6P53_08860	ENOG4105D3Q	Sugar transferase
A6P53_08865	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A6P53_08880	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
A6P53_08885	ENOG4107YJ4	chain length determinant protein
A6P53_08895	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A6P53_08900	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A6P53_08905	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
A6P53_08910	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A6P53_08915	ENOG4107YR5	Diacylglycerol kinase
A6P53_08920	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A6P53_08930	ENOG4105C9A	Phoh family
A6P53_08935	ENOG4105KTH	gatB Yqey
A6P53_08940	ENOG4105VCC	30S ribosomal protein S21
A6P53_08945	ENOG4105N80	Ferric uptake regulator, Fur family
A6P53_08950	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
A6P53_08955	ENOG4105KTU	Transcriptional regulator, arsr family
A6P53_08970	ENOG4105C3M	thioredoxin reductase
A6P53_08975	ENOG4105CS2	ec 3.2.1.21
A6P53_08980	ENOG4105F8D	glycoside hydrolase family 4
A6P53_08990	ENOG4105BZ1	(ABC) transporter
A6P53_08995	ENOG4105BZ1	(ABC) transporter
A6P53_09000	ENOG4105VXM	UPF0154 protein
A6P53_09010	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A6P53_09030	ENOG4105ETE	Transcriptional regulator (LacI family
A6P53_09050	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A6P53_09055	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A6P53_09060	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A6P53_09065	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A6P53_09070	ENOG41086DT	Membrane protein of unknown function
A6P53_09090	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A6P53_09095	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A6P53_09100	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A6P53_09105	ENOG4105E2Z	phosphate ABC transporter (Permease
A6P53_09110	ENOG4105C8U	phosphate abc transporter
A6P53_09115	ENOG4105CVA	phosphate
A6P53_09120	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A6P53_09125	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A6P53_09130	ENOG4105CAK	Cell division ATP-binding protein ftsE
A6P53_09135	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A6P53_09140	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6P53_09160	ENOG4105VZJ	PTS System
A6P53_09170	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A6P53_09175	ENOG4105FDP	GntR family transcriptional regulator
A6P53_09195	ENOG41066F8	ROK family
A6P53_09205	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A6P53_09210	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A6P53_09280	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A6P53_09290	ENOG4105XZU	Preprotein translocase, subunit SecG
A6P53_09295	ENOG410830R	acetyltransferase
A6P53_09330	ENOG4105CP7	Triose-phosphate isomerase
A6P53_09335	ENOG4105BZA	Phosphoglycerate kinase
A6P53_09350	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6P53_09370	ENOG4105CK1	PTS System
A6P53_09375	ENOG4105VZJ	PTS System
A6P53_09385	ENOG4107QSE	Dipeptidase
A6P53_09390	ENOG4105FDP	GntR family transcriptional regulator
A6P53_09415	ENOG4108P49	AntiSigma factor
A6P53_09420	ENOG4105JVQ	RNA Polymerase
A6P53_09425	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
A6P53_09435	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
A6P53_09440	ENOG4105DCI	Phosphohydrolase
A6P53_09445	ENOG410667J	hydrolase
A6P53_09450	ENOG4105M6F	mutator MutT protein
A6P53_09515	ENOG4105RHA	ABC transporter, permease
A6P53_09520	ENOG4108IUX	(ABC) transporter
A6P53_09525	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A6P53_09530	ENOG4105K63	Thioredoxin
A6P53_09535	ENOG4105C98	muts2 protein
A6P53_09550	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6P53_09575	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A6P53_09590	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A6P53_09595	ENOG4105CIF	Ornithine Cyclodeaminase
A6P53_09600	ENOG4107U9B	transcriptional regulator
A6P53_09630	ENOG4105C6K	Malic enzyme
A6P53_09650	ENOG4105BZ1	(ABC) transporter
A6P53_09675	ENOG4105VPH	UPF0473 protein
A6P53_09680	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A6P53_09685	ENOG4105VBH	UPF0297 protein
A6P53_09710	ENOG4108NNR	transporter substrate-binding protein
A6P53_09715	ENOG4108PJD	permease
A6P53_09720	ENOG4105XXY	Thioredoxin
A6P53_09730	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A6P53_09735	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
A6P53_09740	ENOG4105MA4	psp1 domain protein
A6P53_09745	ENOG4105FA2	dna polymerase iii
A6P53_09750	ENOG4105X0R	protein from nitrogen regulatory protein P-II
A6P53_09755	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A6P53_09760	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A6P53_09765	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A6P53_09770	ENOG4105C6E	dna polymerase iii
A6P53_09790	ENOG4105TV1	Transcriptional regulator
A6P53_09800	ENOG4105CZM	Major Facilitator
A6P53_09810	ENOG4105E98	transcriptional regulator DeoR family
A6P53_09815	ENOG4105D2N	Aldolase
A6P53_09820	ENOG4105DM4	PTS System
A6P53_09835	ENOG41082DI	50s ribosomal protein l31
A6P53_09840	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A6P53_09845	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A6P53_09855	ENOG4105D2N	Aldolase
A6P53_09860	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A6P53_09875	ENOG4105C5F	glutamine synthetase
A6P53_09880	ENOG4105KV4	Transcriptional regulator
A6P53_09885	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A6P53_09890	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A6P53_09895	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A6P53_09905	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A6P53_09910	ENOG4108Z0R	Transferase
A6P53_09920	ENOG4105BZ1	(ABC) transporter
A6P53_09930	ENOG4106EHS	UPF0356 protein
A6P53_09945	ENOG4105W5Q	DNA repair protein (RadC
A6P53_09950	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A6P53_09955	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A6P53_09960	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A6P53_09970	ENOG4108YWR	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
A6P53_09975	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A6P53_09980	ENOG4105C3J	Cysteine desulfurase
A6P53_09985	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
A6P53_09995	ENOG4108X4Q	Hydrolase
A6P53_10000	ENOG4105I3N	Conserved Protein
A6P53_10005	ENOG4105HDK	L-asparaginase
A6P53_10015	ENOG4105FGM	Fructosamine kinase
A6P53_10020	ENOG4105CTZ	aminopeptidase c
A6P53_10070	ENOG4105C87	Aminotransferase class I and II
A6P53_10080	ENOG4105CAY	ferredoxin--nadp reductase
A6P53_10085	ENOG4108W5N	phosphatidylglycerophosphatase a
A6P53_10100	ENOG4105MMD	transcriptional regulator
A6P53_10105	ENOG4107R8B	5'-nucleotidase
A6P53_10125	ENOG4108Z6B	deaminase
A6P53_10155	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A6P53_10160	ENOG4105SFS	phosphoesterase RecJ domain protein
A6P53_10170	ENOG4105E8R	UPF0173 metal-dependent hydrolase
A6P53_10185	ENOG4106EMP	CsbD-like
A6P53_10190	ENOG4105DYB	Isoaspartyl dipeptidase
A6P53_10195	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A6P53_10200	ENOG4108SU4	UPF0309 protein
A6P53_10210	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A6P53_10215	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A6P53_10220	ENOG4105E03	chitinase
A6P53_10230	ENOG4108M1A	Chitin-binding protein
A6P53_10235	ENOG4108M1A	Chitin-binding protein
A6P53_10245	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A6P53_10250	ENOG4105F3R	pts system mannose fructose sorbose family iid
A6P53_10255	ENOG4105ETZ	PTS System
A6P53_10265	ENOG4108EQA	pts system
A6P53_10270	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6P53_10275	ENOG4105BZ1	(ABC) transporter
A6P53_10280	ENOG4105BZ1	(ABC) transporter
A6P53_10310	ENOG4108Z5K	methylglyoxal synthase
A6P53_10315	ENOG4108IJ9	(ABC) transporter
A6P53_10320	ENOG4105RNB	
A6P53_10325	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A6P53_10330	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
A6P53_10335	ENOG4105F8V	Hydrolase, tatD family
A6P53_10340	ENOG4107R7I	amino acid
A6P53_10355	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A6P53_10405	ENOG4108DMH	HTH_ARAC
A6P53_10435	ENOG4107QQG	Dehydrogenase
A6P53_10445	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
A6P53_10455	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A6P53_10460	ENOG4105EY8	ABC transporter
A6P53_10505	ENOG4105D7V	transposase
A6P53_10510	ENOG4108JQ7	(ABC) transporter
A6P53_10520	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6P53_10525	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A6P53_10545	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A6P53_10550	ENOG4105CNU	cell division protein FtsK
A6P53_10555	ENOG4105CS2	ec 3.2.1.21
A6P53_10560	ENOG4106TNF	Periplasmic binding protein
A6P53_10565	ENOG4105CDA	abc transporter atp-binding protein
A6P53_10570	ENOG4105E5Q	amino acid AbC transporter
A6P53_10595	ENOG4105C6X	Major Facilitator
A6P53_10600	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6P53_10605	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A6P53_10655	ENOG4105C3J	Cysteine desulfurase
A6P53_10660	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A6P53_10670	ENOG4105C9K	Endothelin-converting enzyme 1
A6P53_10680	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A6P53_10695	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A6P53_10705	ENOG4108YZ4	nudix hydrolase
A6P53_10715	ENOG4105CDW	Resistance protein
A6P53_10720	ENOG4105CUB	amino acid
A6P53_10725	ENOG4105CSC	Glucose uptake protein
A6P53_10730	ENOG4105EWM	Histidine kinase
A6P53_10735	ENOG4105CJZ	response regulator
A6P53_10745	ENOG4105DRS	transport system, permease
A6P53_10750	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
A6P53_10760	ENOG4105WEF	catalase
A6P53_10765	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A6P53_10780	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
A6P53_10790	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A6P53_10795	ENOG4107VFR	oxidoreductase
A6P53_10800	ENOG4108I7Y	domain protein
A6P53_10805	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A6P53_10815	ENOG4105DSE	periplasmic solute binding protein
A6P53_10820	ENOG4105CC5	ABC transporter
A6P53_10825	ENOG4105DIK	(ABC) transporter
A6P53_10840	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A6P53_10845	ENOG4108R6W	Transcriptional regulator, ARAC family
A6P53_10850	ENOG4107RBJ	symporter
A6P53_10855	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A6P53_10860	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A6P53_10880	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
A6P53_10885	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
A6P53_10900	ENOG4105EYH	Exonuclease
A6P53_10905	ENOG4107RFY	SbcCD D subunit
A6P53_10910	ENOG4105F6E	Acyl-transferase
A6P53_10915	ENOG41060K3	Methyltransferase
A6P53_10920	ENOG4105VC4	domain protein
A6P53_10925	ENOG4105EXC	Acyl-transferase
A6P53_10930	ENOG4107AYK	membrAne
A6P53_10935	ENOG4105C9M	aspartyl-trna synthetase
A6P53_10940	ENOG4105CUT	histidyl-tRNA synthetase
A6P53_10945	ENOG4105CPC	Aldo Keto reductase
A6P53_10955	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A6P53_10960	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A6P53_10965	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A6P53_10970	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A6P53_10980	ENOG4108VX5	3-methyladenine DNA glycosylase
A6P53_10990	ENOG4105D1H	recombination factor protein RarA
A6P53_11005	ENOG4107YZX	Universal stress protein
A6P53_11025	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A6P53_11055	ENOG4106855	Competence protein
A6P53_11075	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A6P53_11095	ENOG4105K59	histidine triad (HIT) protein
A6P53_11105	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
A6P53_11115	ENOG4105EQI	Metal Dependent Phosphohydrolase
A6P53_11120	ENOG4106D4I	domain protein
A6P53_11150	ENOG4105WZB	UPF0342 protein
A6P53_11155	ENOG4105BZ4	penicillin-binding protein
A6P53_11160	ENOG4108YBP	pseudouridine synthase
A6P53_11165	ENOG4105EVU	fructokinase
A6P53_11170	ENOG4105C8I	hydrolase, family 38
A6P53_11195	ENOG4105CSH	Transporter
A6P53_11205	ENOG4107REC	cytoplasmic protein
A6P53_11215	ENOG4107VHA	regulatoR
A6P53_11225	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A6P53_11235	ENOG4105CS2	ec 3.2.1.21
A6P53_11245	ENOG4105CK1	PTS System
A6P53_11260	ENOG4108U3J	
A6P53_11290	ENOG4105DZR	Type I site-specific deoxyribonuclease
A6P53_11315	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A6P53_11320	ENOG4105C0H	protease
A6P53_11325	ENOG4108VDD	TRNA binding domain protein
A6P53_11345	ENOG4105F3R	pts system mannose fructose sorbose family iid
A6P53_11350	ENOG4105ETZ	PTS System
A6P53_11355	ENOG4108IQ3	PTS system
A6P53_11360	ENOG4105FDP	GntR family transcriptional regulator
A6P53_11365	ENOG4107YZX	Universal stress protein
A6P53_11375	ENOG4105CN9	Peptidase m42 family protein
A6P53_11385	ENOG410838F	Glycosyl transferase family 2
A6P53_11405	ENOG4105CND	Glycosyl transferase, family 2
A6P53_11415	ENOG4105EEM	helicase
A6P53_11420	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A6P53_11425	ENOG4105WZW	rhodanese family
A6P53_11430	ENOG4105VPX	protein, conserved in bacteria
A6P53_11440	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
A6P53_11445	ENOG4105C98	muts2 protein
A6P53_11450	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A6P53_11455	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A6P53_11460	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A6P53_11470	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A6P53_11495	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6P53_11500	ENOG4105FS7	Transcriptional regulator
A6P53_11520	ENOG4105CG3	alpha amylase, catalytic region
A6P53_11525	ENOG4105C7N	Xanthine uracil vitamin C permease
A6P53_11540	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A6P53_11550	ENOG4108U05	Transcriptional regulator
A6P53_11570	ENOG4105C85	amino acid
A6P53_11575	ENOG4105C85	amino acid
A6P53_11615	ENOG4107SFZ	crispr-associated protein
A6P53_11625	ENOG4105CCI	Myosin-Cross-Reactive Antigen
A6P53_11635	ENOG4105E2A	Dehydrogenase
A6P53_11650	ENOG4105CK1	PTS System
A6P53_11655	ENOG4105VCP	PTS System
A6P53_11660	ENOG4105VZJ	PTS System
A6P53_11670	ENOG4105CPC	Aldo Keto reductase
A6P53_11680	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A6P53_11695	ENOG4105EQD	regulatoR
A6P53_11700	ENOG4105C2F	Histidine kinase
A6P53_11715	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A6P53_11720	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
A6P53_11740	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A6P53_11745	ENOG4105CK1	PTS System
A6P53_11755	ENOG4105VCP	PTS System
A6P53_11760	ENOG4105EMD	TRANSCRIPTIONal
A6P53_11775	ENOG4105C8T	Leucyl-tRNA synthetase
A6P53_11785	ENOG410841Q	phosphoesterase PA-phosphatase related protein
A6P53_11790	ENOG4105N5T	Radical SAM Protein
A6P53_11820	ENOG4105BZ1	(ABC) transporter
A6P53_11825	ENOG4105BZ1	(ABC) transporter
A6P53_11835	ENOG4108S4H	thioesterase Superfamily protein
A6P53_11845	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A6P53_11850	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A6P53_12000	ENOG4105CRK	lysyL-tRNA synthetase
A6P53_12005	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A6P53_12010	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A6P53_12015	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A6P53_12020	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A6P53_12025	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A6P53_12030	ENOG41060GV	RNA binding s1 domain protein
A6P53_12040	ENOG41082I2	s4 domain protein
A6P53_12050	ENOG4108JA2	transcriptioN-repair coupling factor
A6P53_12055	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A6P53_12060	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A6P53_12095	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A6P53_12105	ENOG4105DJV	ribulose-phosphate 3-epimerase
A6P53_12110	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A6P53_12115	ENOG4105D9P	serine threonine protein kinase
A6P53_12120	ENOG4108ZF3	Phosphatase
A6P53_12125	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A6P53_12130	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A6P53_12135	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A6P53_12140	ENOG4105C25	Primosomal protein n'
A6P53_12145	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A6P53_12150	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A6P53_12160	ENOG4105DSJ	YicC domain protein
A6P53_12185	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A6P53_12190	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A6P53_12195	ENOG4105DFT	pur operon repressor
A6P53_12205	ENOG4105FDK	ABC transporter
A6P53_12210	ENOG4105DSE	periplasmic solute binding protein
A6P53_12215	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A6P53_12235	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
A6P53_12245	ENOG4105CEV	competence damage-inducible protein
A6P53_12250	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A6P53_12270	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A6P53_12275	ENOG4107YB6	acetyltransferase, (GNAT) family
A6P53_12280	ENOG4105W42	Veg protein
A6P53_12290	ENOG4105M0M	Tetracycline resistance protein
A6P53_12295	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A6P53_12300	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A6P53_12305	ENOG4105C8N	cysteinyl-tRNA synthetase
A6P53_12310	ENOG4105D7W	serine acetyltransferase
A6P53_12315	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A6P53_12320	ENOG4105CTP	PilT protein domain protein
A6P53_12330	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A6P53_12335	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A6P53_12340	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A6P53_12355	ENOG4105DXB	Major Facilitator superfamily
A6P53_12365	ENOG41081I9	integral membrane protein
A6P53_12370	ENOG4105ECR	NmrA family
A6P53_12375	ENOG4108Z40	Transcriptional regulator
A6P53_12385	ENOG4105EC2	ftsk spoIIIe
A6P53_12400	ENOG410646G	Proteins of 100 residues with WXG
A6P53_12405	ENOG4105FE1	phytoene synthase
A6P53_12410	ENOG4105EWK	phytoene
A6P53_12425	ENOG4105E3A	(ABC) transporter
A6P53_12430	ENOG4105DA5	(ABC) transporter
A6P53_12435	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A6P53_12445	ENOG4105CS2	ec 3.2.1.21
A6P53_12455	ENOG4108M15	ABC transporter
A6P53_12465	ENOG4108ZGX	Histidine kinase
A6P53_12485	ENOG4105D2N	Aldolase
A6P53_12490	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
A6P53_12495	ENOG4105DT3	PTS system, galactitol-specific IIc component
A6P53_12500	ENOG41082GB	PTS system galactitol-specific transporter subunit IIA
A6P53_12510	ENOG4105C0D	helicase
A6P53_12530	ENOG4108UJD	30S ribosomal protein S9
A6P53_12535	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A6P53_12540	ENOG4105HUF	DNA protection during starvation protein
A6P53_12545	ENOG4105CMG	Carbohydrate kinase
A6P53_12555	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A6P53_12565	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6P53_12570	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6P53_12585	ENOG4105C7J	ABC transporter, permease
A6P53_12595	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A6P53_12605	ENOG4105EAH	synthase
A6P53_12625	ENOG41088B0	Major membrane immunogen
A6P53_12700	ENOG4105DC8	reductase
A6P53_12705	ENOG4105CFP	Peptidase U32
A6P53_12710	ENOG4105XYU	peptidase (U32 family)
A6P53_12715	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6P53_12720	ENOG4105KEX	transcriptional regulator, ctsr
A6P53_12795	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A6P53_12800	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6P53_12805	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A6P53_12815	ENOG4105C3G	gtp-binding protein
A6P53_12820	ENOG4105VDK	protein, conserved in bacteria
A6P53_12825	ENOG4105FA0	parb-like partition protein
A6P53_12830	ENOG4107QJE	Chromosome Partitioning Protein
A6P53_12835	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A6P53_12845	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A6P53_12850	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A6P53_12865	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A6P53_12870	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A6P53_12875	ENOG4105VG0	50S ribosomal protein l34
A6P53_12955	ENOG4107QJE	Chromosome Partitioning Protein
A6P53_13000	ENOG4105K4H	Nlp p60 protein
A6P53_13020	ENOG4106PHI	plasmid recombination enzyme
A6P53_13080	ENOG4108UUM	single-stranded DNA-binding protein
A6P53_13095	ENOG4105C9U	ATP-dependent DNA helicase RecQ