locus-tag	class	description
MACHINA_117	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MACHINA_218	COG0328	RNA-DNA hybrid ribonuclease activity
MACHINA_73	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis