locus-tag	class	description
HQR01_00015	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HQR01_00070	ENOG4105DVT	helicase
HQR01_00080	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HQR01_00100	ENOG4108Z4X	TRANSCRIPTIONal
HQR01_00110	ENOG4105CI2	imidazolone-5-propionate hydrolase
HQR01_00115	ENOG4105NPE	arsR family transcriptional regulator
HQR01_00125	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HQR01_00130	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HQR01_00165	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
HQR01_00170	ENOG4105CNG	UPF0061 protein
HQR01_00175	ENOG4105C26	Dehydrogenase
HQR01_00195	ENOG4105EKE	dihydroorotase
HQR01_00200	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HQR01_00220	ENOG4105K46	50S ribosomal protein l27
HQR01_00225	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HQR01_00240	ENOG4108ZAF	Molybdopterin
HQR01_00265	ENOG4105D98	threonine synthase
HQR01_00280	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HQR01_00285	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HQR01_00290	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HQR01_00300	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HQR01_00310	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HQR01_00315	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HQR01_00320	ENOG4105C3F	Signal peptidase i
HQR01_00335	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HQR01_00350	ENOG4108JQC	penicillin-binding protein 1A
HQR01_00380	ENOG4108IG5	Transcriptional regulator
HQR01_00390	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
HQR01_00415	ENOG4105EUB	pirin domain protein
HQR01_00420	ENOG4108IXY	short-chain dehydrogenase reductase
HQR01_00425	ENOG4105D74	hydrolase
HQR01_00435	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HQR01_00445	ENOG4107XZX	Involved in the transcription termination process (By similarity)
HQR01_00450	ENOG4108SA1	esterase
HQR01_00455	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HQR01_00460	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HQR01_00490	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HQR01_00495	ENOG4105C1J	atp-dependent rna helicase
HQR01_00510	ENOG4105IJJ	transcriptional regulator, crp fnr family
HQR01_00520	ENOG4105MP9	class II Aldolase
HQR01_00545	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HQR01_00555	ENOG4105XEA	Tetr family transcriptional regulator
HQR01_00560	ENOG41082BM	Transcriptional regulator, arsr family
HQR01_00575	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HQR01_00580	ENOG4107QHQ	amino acid
HQR01_00585	ENOG4105CBX	hi0933 family
HQR01_00605	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HQR01_00610	ENOG4108Z03	MAF-like protein
HQR01_00635	ENOG4105EEQ	Na H antiporter
HQR01_00645	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HQR01_00650	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HQR01_00655	ENOG4107QPR	SAICAR synthetase
HQR01_00665	ENOG4107RAN	Peptidase, M16
HQR01_00670	ENOG4107ZSV	Receptor
HQR01_00675	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HQR01_00680	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HQR01_00685	ENOG4105BZU	Histidine kinase
HQR01_00730	ENOG4105CEY	Amp-dependent synthetase and ligase
HQR01_00740	ENOG4105C09	Bile acid
HQR01_00755	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HQR01_00785	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HQR01_00790	ENOG4105W8H	transhydrogenase (subunit alpha
HQR01_00795	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HQR01_00815	ENOG4105EEI	dihydropteroate synthase
HQR01_00820	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HQR01_00840	ENOG4105CEC	DNA methylase N-4 N-6
HQR01_00860	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HQR01_00880	ENOG4108JW7	Maf-like protein
HQR01_00885	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HQR01_00895	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HQR01_00905	ENOG4108W2Y	isochorismatase
HQR01_00930	ENOG4105C3J	Cysteine desulfurase
HQR01_00935	ENOG4107QI6	Cysteine desulfurase
HQR01_00940	ENOG4105DHZ	alpha beta
HQR01_00970	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HQR01_00975	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HQR01_00980	ENOG4105EB3	Histidine kinase
HQR01_00985	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HQR01_00990	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HQR01_00995	ENOG4105DAS	pts system
HQR01_01005	ENOG4108RWN	rrna methyltransferase
HQR01_01055	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HQR01_01060	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HQR01_01065	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HQR01_01070	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HQR01_01080	ENOG4105HDK	L-asparaginase
HQR01_01090	ENOG41061H0	Monooxygenase
HQR01_01095	ENOG4107ZT5	Thiol disulfide interchange protein
HQR01_01100	ENOG4105CH7	arginosuccinase
HQR01_01115	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HQR01_01120	ENOG4108R96	Methyltransferase, YaeB family
HQR01_01135	ENOG4105EMN	RNA polymerase sigma factor
HQR01_01150	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HQR01_01170	ENOG4105C72	UPF0176 protein
HQR01_01175	ENOG4105CJ3	phosphate transporter
HQR01_01185	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HQR01_01195	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HQR01_01205	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HQR01_01215	ENOG4105NTW	Transcriptional regulator
HQR01_01220	ENOG4105D1H	recombination factor protein RarA
HQR01_01270	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HQR01_01275	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HQR01_01290	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HQR01_01300	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HQR01_01310	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HQR01_01315	ENOG4105D64	Mechanosensitive ion channel
HQR01_01320	ENOG4105C28	cystathionine
HQR01_01325	ENOG4105KHC	sulfurtransferase
HQR01_01335	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HQR01_01360	ENOG4105HFZ	Membrane
HQR01_01380	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HQR01_01385	ENOG4108UFP	Essential cell division protein (By similarity)
HQR01_01390	ENOG4105CPF	Cell wall formation (By similarity)
HQR01_01395	ENOG4105D4A	Cell wall formation (By similarity)
HQR01_01400	ENOG4105DFU	Cell wall formation (By similarity)
HQR01_01405	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HQR01_01415	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HQR01_01420	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HQR01_01445	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HQR01_01450	ENOG4107YUR	Cell division protein mraZ
HQR01_01485	ENOG4105KZX	Pterin carbinolamine dehydratase
HQR01_01490	ENOG4107R7I	amino acid
HQR01_01495	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HQR01_01500	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HQR01_01505	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HQR01_01515	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HQR01_01530	ENOG4108YZA	Nitrogen regulatory protein pii
HQR01_01535	ENOG4105C5F	glutamine synthetase
HQR01_01540	ENOG4105C3J	Cysteine desulfurase
HQR01_01570	ENOG4105CFU	surface antigen
HQR01_01575	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HQR01_01580	ENOG4105C7B	Threonine dehydratase
HQR01_01590	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HQR01_01595	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HQR01_01600	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HQR01_01605	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HQR01_01610	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HQR01_01615	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HQR01_01625	ENOG4105C75	arginyL-tRNA synthetase
HQR01_01635	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HQR01_01640	ENOG4105CUV	Homoserine Kinase
HQR01_01645	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HQR01_01650	ENOG4106178	UPF0339 protein
HQR01_01655	ENOG4105FC8	fad dependent oxidoreductase
HQR01_01705	ENOG4105CGU	Enoyl-CoA hydratase
HQR01_01715	ENOG4105CHU	acetyl-coa acetyltransferase
HQR01_01720	ENOG4105D05	Receptor
HQR01_01730	ENOG4107RDJ	Sulfotransferase
HQR01_01750	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HQR01_01760	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_01805	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HQR01_01810	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HQR01_01815	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HQR01_01835	ENOG41082CG	Protein CrcB homolog
HQR01_01840	ENOG4105EI2	Pseudouridine synthase
HQR01_01880	ENOG4105DHJ	ABC, transporter
HQR01_01885	ENOG4105CY3	ABC transporter, permease
HQR01_01890	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HQR01_01895	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HQR01_01925	ENOG410802X	bacteriophage n4 adsorption protein b
HQR01_01930	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HQR01_01950	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HQR01_01970	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HQR01_02000	ENOG4105CH2	amidohydrolase
HQR01_02010	ENOG4105PGM	cation diffusion facilitator family transporter
HQR01_02035	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HQR01_02040	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HQR01_02045	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HQR01_02055	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HQR01_02070	ENOG41067HS	methyltransferase
HQR01_02075	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HQR01_02080	ENOG4105BZU	Histidine kinase
HQR01_02085	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HQR01_02095	ENOG41083MR	nifu domain-containing protein
HQR01_02105	ENOG41072GX	Peptidase M22 Glycoprotease
HQR01_02115	ENOG4108YXV	Transcriptional regulator
HQR01_02120	ENOG41090R7	Ferric uptake
HQR01_02135	ENOG4107RCQ	(CBS) domain
HQR01_02140	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HQR01_02155	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HQR01_02165	ENOG4105CJW	magnesium transporter
HQR01_02170	ENOG4108Y50	Glutathione-dependent formaldehyde-activating Gfa
HQR01_02190	ENOG4105E09	nadh pyrophosphatase
HQR01_02205	ENOG4105CEN	a g-specific adenine glycosylase
HQR01_02225	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HQR01_02250	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HQR01_02255	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HQR01_02260	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HQR01_02265	ENOG41067VY	50S ribosomal protein L32
HQR01_02275	ENOG4105C5X	domain protein
HQR01_02290	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HQR01_02335	ENOG4105C8N	cysteinyl-tRNA synthetase
HQR01_02340	ENOG4105IB0	filamentous hemagglutinin family outer membrane protein
HQR01_02365	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HQR01_02375	ENOG4105C25	Primosomal protein n'
HQR01_02385	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HQR01_02405	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HQR01_02410	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HQR01_02415	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HQR01_02425	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HQR01_02430	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HQR01_02445	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HQR01_02455	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HQR01_02475	ENOG4105D7W	serine acetyltransferase
HQR01_02490	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HQR01_02495	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HQR01_02515	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HQR01_02530	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HQR01_02545	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HQR01_02550	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HQR01_02555	ENOG4107QP3	malate synthase g
HQR01_02570	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HQR01_02595	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HQR01_02635	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HQR01_02640	ENOG4108UJV	acyl-CoA thioesterase i
HQR01_02645	ENOG4108I0Y	(ABC) transporter
HQR01_02650	ENOG4105CV6	ABC transporter, permease
HQR01_02660	ENOG4105D05	Receptor
HQR01_02665	ENOG4105CI3	gtp-binding protein typa
HQR01_02680	ENOG4105CK7	Sodium proline symporter
HQR01_02720	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HQR01_02775	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HQR01_02785	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HQR01_02795	ENOG4108IG5	Transcriptional regulator
HQR01_02800	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_02805	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HQR01_02860	ENOG4108JJ7	ABC transporter
HQR01_02865	ENOG4105CHH	sulfate transporter
HQR01_02875	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HQR01_02880	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HQR01_02910	ENOG4108UUM	single-stranded DNA-binding protein
HQR01_02915	ENOG4105CE1	Ferrous iron transport protein b
HQR01_02940	ENOG4108ZZ3	UPF0260 protein
HQR01_02955	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HQR01_02965	ENOG4105RWF	major outer membrane protein OmpA
HQR01_02985	ENOG4105CGF	Aromatic amino acid aminotransferase
HQR01_03040	ENOG4105CHM	Aminotransferase
HQR01_03045	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HQR01_03055	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HQR01_03070	ENOG4105XYF	acetyltransferase
HQR01_03085	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HQR01_03090	ENOG41074H6	response regulator
HQR01_03095	ENOG410903D	sensor protein
HQR01_03125	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HQR01_03135	ENOG4105DWF	phosphomethylpyrimidine kinase
HQR01_03150	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HQR01_03155	ENOG4106ECF	Uncharacterized protein conserved in bacteria (DUF2155)
HQR01_03175	ENOG4107RCI	amp-dependent synthetase and ligase
HQR01_03210	ENOG4105D9N	nucleoside
HQR01_03220	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HQR01_03235	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HQR01_03260	ENOG410903C	(LipO)protein
HQR01_03270	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HQR01_03285	ENOG4105C8P	)-transporter
HQR01_03295	ENOG4105C28	cystathionine
HQR01_03315	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HQR01_03325	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HQR01_03330	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HQR01_03340	ENOG4105SG9	biopolymer transport protein, ExbD
HQR01_03345	ENOG4105E02	MotA TolQ exbB proton channel
HQR01_03350	ENOG4107YD3	Thioesterase
HQR01_03355	ENOG4105K59	histidine triad (HIT) protein
HQR01_03360	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HQR01_03365	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HQR01_03370	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HQR01_03380	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HQR01_03395	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HQR01_03405	ENOG4105CHR	reductase
HQR01_03410	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_03415	ENOG4105X7H	acyl-CoA dehydrogenase
HQR01_03420	ENOG4105CHR	reductase
HQR01_03445	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HQR01_03520	ENOG4108U78	Glutathione S-transferase
HQR01_03540	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HQR01_03545	ENOG4108UPT	UPF0178 protein
HQR01_03600	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HQR01_03620	ENOG4105EJC	lysr family transcriptional regulator
HQR01_03640	ENOG4107R5W	Monooxygenase
HQR01_03650	ENOG4105EJC	lysr family transcriptional regulator
HQR01_03655	ENOG4108RCM	Nitroreductase
HQR01_03675	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HQR01_03680	ENOG4105G9V	cytochrome C
HQR01_03695	ENOG4105D44	asparaginase
HQR01_03700	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HQR01_03715	ENOG4105E18	UPF0276 protein
HQR01_03780	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HQR01_03795	ENOG4108I0Z	Aconitate hydratase
HQR01_03800	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HQR01_03815	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HQR01_03820	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HQR01_03845	ENOG4108JU3	Alkyl hydroperoxide reductase
HQR01_03880	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HQR01_03885	ENOG4105CJR	Integral membrane protein (MviN
HQR01_03890	ENOG4105C31	Tryptophanyl-tRNA synthetase
HQR01_03900	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HQR01_03905	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HQR01_03915	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HQR01_03925	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HQR01_03945	ENOG4107QPD	alcohol dehydrogenase
HQR01_03965	ENOG4105C4W	S-formylglutathione hydrolase
HQR01_03970	ENOG410756H	nucleotidyltransferase
HQR01_03975	ENOG4105DWV	Homoserine O-trans-acetylase
HQR01_03990	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HQR01_04005	ENOG4107SRH	Nad-dependent epimerase dehydratase
HQR01_04030	ENOG4105CAK	Cell division ATP-binding protein ftsE
HQR01_04035	ENOG4106D71	domain protein
HQR01_04085	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HQR01_04110	ENOG4108W6C	Dehydrogenase
HQR01_04120	ENOG4105CHR	reductase
HQR01_04130	ENOG4105DHP	deoxycytidine triphosphate deaminase
HQR01_04140	ENOG4105EG6	Saccharopine dehydrogenase
HQR01_04145	ENOG4105D05	Receptor
HQR01_04175	ENOG4105ES4	Nitrilase
HQR01_04200	ENOG4107QK9	Beta-lactamase
HQR01_04215	ENOG4105CYM	Glutathione S-transferase
HQR01_04225	ENOG4105VSH	4-oxalocrotonate tautomerase
HQR01_04235	ENOG4108K3A	Glutathione S-transferase
HQR01_04245	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HQR01_04275	ENOG41060WC	Enoyl-CoA hydratase
HQR01_04315	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HQR01_04325	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HQR01_04335	ENOG4105CAS	nag kinase
HQR01_04345	ENOG4105CHR	reductase
HQR01_04365	ENOG4105Z2P	Protein of unknown function (DUF465)
HQR01_04385	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HQR01_04400	ENOG4105BZU	Histidine kinase
HQR01_04410	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HQR01_04420	ENOG4105DUX	Transporter
HQR01_04440	ENOG4105E0A	ABC, transporter
HQR01_04445	ENOG4108IYU	L-aspartate oxidase
HQR01_04455	ENOG4105DA5	(ABC) transporter
HQR01_04465	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HQR01_04490	ENOG4108I5G	Major Facilitator superfamily
HQR01_04505	ENOG4105CEY	Amp-dependent synthetase and ligase
HQR01_04510	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HQR01_04525	ENOG4105EJQ	L-serine dehydratase
HQR01_04535	ENOG4105F4G	Membrane
HQR01_04580	ENOG4107QX3	carboxylase
HQR01_04590	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_04605	ENOG4108IJ8	ABC transporter
HQR01_04625	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HQR01_04630	ENOG4105CEY	Amp-dependent synthetase and ligase
HQR01_04635	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HQR01_04640	ENOG4105DFA	alanine racemase domain protein
HQR01_04645	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HQR01_04650	ENOG4105CNU	cell division protein FtsK
HQR01_04655	ENOG4105BZN	citrate synthase
HQR01_04660	ENOG4105BZN	citrate synthase
HQR01_04670	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HQR01_04685	ENOG4105DCF	alanine dehydrogenase
HQR01_04690	ENOG4106TD9	Diguanylate cyclase
HQR01_04695	ENOG4105BZU	Histidine kinase
HQR01_04710	ENOG4105DC7	peptidase M24
HQR01_04735	ENOG4105JJR	Histidine kinase
HQR01_04745	ENOG4105D7A	ATP-binding protein
HQR01_04750	ENOG4105CRQ	synthase (Component I)
HQR01_04760	ENOG4108YZN	class I peptide chain release factor
HQR01_04765	ENOG4105W0E	50S ribosomal protein L33
HQR01_04785	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HQR01_04815	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HQR01_04835	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
HQR01_04840	ENOG4105CHU	acetyl-coa acetyltransferase
HQR01_04845	ENOG4108M9J	MaoC like domain protein
HQR01_04855	ENOG4105CSR	polyphosphate kinase 2
HQR01_04860	ENOG4105MIR	Phenylalanine 4-monooxygenase
HQR01_04875	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HQR01_04880	ENOG4105BZ1	(ABC) transporter
HQR01_04895	ENOG4105CHU	acetyl-coa acetyltransferase
HQR01_04935	ENOG4105E39	Enoyl-CoA hydratase
HQR01_04940	ENOG4105CHR	reductase
HQR01_04945	ENOG4107S1E	Beta-lactamase
HQR01_04950	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HQR01_04955	ENOG4107U9H	DNA polymerase
HQR01_04985	ENOG4105C8T	Leucyl-tRNA synthetase
HQR01_04990	ENOG4105TXM	Domain of unknown function (DUF3576)
HQR01_05000	ENOG4105CHR	reductase
HQR01_05020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HQR01_05025	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HQR01_05035	ENOG4107S78	Band 7 protein
HQR01_05060	ENOG4105DR5	peptidase
HQR01_05065	ENOG4105ED9	Protein of unknown function (DUF455)
HQR01_05070	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HQR01_05075	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HQR01_05085	ENOG4105DWY	Agmatine deiminase
HQR01_05100	ENOG4105C22	threonyL-tRNA synthetase
HQR01_05105	ENOG4108K3A	Glutathione S-transferase
HQR01_05110	ENOG4105DGI	Alkaline phosphatase
HQR01_05130	ENOG4108M3P	Membrane
HQR01_05135	ENOG4105D0M	Protease HtpX homolog
HQR01_05150	ENOG4105DEN	Luciferase family
HQR01_05155	ENOG4105C7I	Dehydrogenase
HQR01_05165	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HQR01_05170	ENOG4108IUX	(ABC) transporter
HQR01_05185	ENOG4105E0X	reductase
HQR01_05200	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HQR01_05205	ENOG4105FDP	GntR family transcriptional regulator
HQR01_05210	ENOG4105DUX	Transporter
HQR01_05215	ENOG4105CI2	imidazolone-5-propionate hydrolase
HQR01_05225	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HQR01_05235	ENOG4108UKI	Enoyl-CoA hydratase
HQR01_05250	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HQR01_05260	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HQR01_05265	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HQR01_05275	ENOG4105DJV	ribulose-phosphate 3-epimerase
HQR01_05280	ENOG4105Z85	coenzyme PQQ synthesis
HQR01_05295	ENOG4105BZ1	(ABC) transporter
HQR01_05350	ENOG4105D0M	Protease HtpX homolog
HQR01_05365	ENOG4108HRK	Histidine kinase
HQR01_05370	ENOG4108NEV	two component transcriptional regulator, LytTR family
HQR01_05375	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HQR01_05380	ENOG4105KPV	Transcriptional regulator
HQR01_05385	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HQR01_05400	ENOG4108Z6B	deaminase
HQR01_05405	ENOG4105KDC	50s ribosomal protein l28
HQR01_05415	ENOG4108K5P	(LipO)protein
HQR01_05425	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HQR01_05430	ENOG4105C12	Phosphoribosylglycinamide synthetase
HQR01_05460	ENOG4108Z4V	iron-sulfur cluster assembly
HQR01_05470	ENOG4105VG1	fes assembly suf system protein
HQR01_05475	ENOG4105C9B	Cysteine desulfurase
HQR01_05480	ENOG4105JRK	feS assembly protein SufD
HQR01_05485	ENOG4105C3K	feS assembly ATPase SufC
HQR01_05510	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HQR01_05515	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HQR01_05535	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HQR01_05545	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HQR01_05550	ENOG4105VF7	tolerance protein
HQR01_05555	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HQR01_05560	ENOG4108UJD	30S ribosomal protein S9
HQR01_05585	ENOG4108NEV	two component transcriptional regulator, LytTR family
HQR01_05590	ENOG4108HRK	Histidine kinase
HQR01_05595	ENOG4107GFK	fumarate
HQR01_05600	ENOG4108KE4	O-methyltransferase
HQR01_05605	ENOG4105DFG	type I secretion outer membrane protein
HQR01_05615	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HQR01_05630	ENOG41080XP	Cbs domain
HQR01_05635	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HQR01_05645	ENOG4105F0V	Cell wall hydrolase
HQR01_05660	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
HQR01_05670	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HQR01_05675	ENOG4105E2X	shikimate dehydrogenase
HQR01_05680	ENOG4108UHJ	MAF-like protein
HQR01_05685	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HQR01_05690	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HQR01_05700	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HQR01_05720	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HQR01_05725	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HQR01_05730	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
HQR01_05760	ENOG4105CSU	acyl-Coa dehydrogenase
HQR01_05765	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HQR01_05780	ENOG4108VJ1	Transcriptional regulator (CarD family
HQR01_05785	ENOG4108Z4U	Ferredoxin
HQR01_05800	ENOG4105E4C	Lytic transglycosylase catalytic
HQR01_05805	ENOG4105D52	delta-aminolevulinic acid dehydratase
HQR01_05825	ENOG410856B	UPF0235 protein
HQR01_05835	ENOG4107TYR	Glycosyl Transferase
HQR01_05865	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HQR01_05875	ENOG4105CEY	Amp-dependent synthetase and ligase
HQR01_05885	ENOG4105DR5	peptidase
HQR01_05890	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HQR01_05900	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HQR01_05910	ENOG4105CN1	protease
HQR01_05930	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HQR01_05935	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HQR01_05940	ENOG4107U9T	Pfam:Ribonuclease_BN
HQR01_05945	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HQR01_05950	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HQR01_05955	ENOG41076HS	cation diffusion facilitator family transporter
HQR01_05960	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
HQR01_05985	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HQR01_06015	ENOG4106BRA	Membrane
HQR01_06030	ENOG4105C10	Electron transfer flavoprotein
HQR01_06035	ENOG4105BZJ	Electron transfer flavoprotein
HQR01_06045	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HQR01_06050	ENOG4107TK4	histidinol-phosphate phosphatase
HQR01_06055	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HQR01_06075	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HQR01_06080	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HQR01_06085	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HQR01_06095	ENOG4108IGT	Dipeptidase
HQR01_06100	ENOG4105DTN	riboflavin biosynthesis protein ribF
HQR01_06115	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HQR01_06160	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HQR01_06170	ENOG4105CD8	aminopeptidase N
HQR01_06175	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HQR01_06180	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HQR01_06185	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HQR01_06190	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HQR01_06195	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HQR01_06215	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HQR01_06220	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HQR01_06235	ENOG4107QRT	dEAD DEAH box helicase
HQR01_06250	ENOG4105M8F	Biopolymer transport protein exbD tolR
HQR01_06275	ENOG4105D6E	homoserine dehydrogenase
HQR01_06285	ENOG4105CBT	Fructose-1,6-bisphosphatase
HQR01_06300	ENOG4107TK4	histidinol-phosphate phosphatase
HQR01_06305	ENOG4105CHR	reductase
HQR01_06315	ENOG41082BR	50S ribosomal protein L35
HQR01_06320	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HQR01_06340	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HQR01_06345	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HQR01_06355	ENOG4105EMU	Dehydrogenase
HQR01_06360	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HQR01_06365	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HQR01_06380	ENOG4108YZA	Nitrogen regulatory protein pii
HQR01_06385	ENOG4105BZU	Histidine kinase
HQR01_06390	ENOG4107ZSV	Receptor
HQR01_06410	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
HQR01_06425	ENOG4105C8Y	Acetylornithine aminotransferase
HQR01_06430	ENOG4105DBV	ornithine carbamoyltransferase
HQR01_06435	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HQR01_06445	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HQR01_06455	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HQR01_06460	ENOG4105UYK	outer membrane protein a
HQR01_06480	ENOG4108UM1	dedA family
HQR01_06500	ENOG4105CC0	LysR family Transcriptional regulator
HQR01_06510	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HQR01_06515	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HQR01_06580	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HQR01_06585	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
HQR01_06610	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HQR01_06625	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HQR01_06635	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HQR01_06640	ENOG4105C6K	Malic enzyme
HQR01_06650	ENOG4108RU0	short-chain dehydrogenase reductase
HQR01_06655	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HQR01_06660	ENOG410635A	Membrane
HQR01_06675	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HQR01_06680	ENOG4108IUZ	ABC transporter
HQR01_06690	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HQR01_06695	ENOG4105D8X	mechanosensitive ion channel
HQR01_06700	ENOG4105F0N	pyrophosphate phospho-hydrolase
HQR01_06710	ENOG4105CUT	histidyl-tRNA synthetase
HQR01_06715	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HQR01_06720	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HQR01_06730	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HQR01_06735	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HQR01_06740	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HQR01_06790	ENOG4105EGS	Mechanosensitive ion channel
HQR01_06795	ENOG410903D	sensor protein
HQR01_06800	ENOG4105C2M	dna polymerase I
HQR01_06820	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_06845	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HQR01_06850	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HQR01_06855	ENOG4107QI1	Mate efflux family protein
HQR01_06865	ENOG4105DR5	peptidase
HQR01_06960	ENOG4105DZ2	Transcriptional regulator
HQR01_06970	ENOG4105C5H	ABC transporter
HQR01_06990	ENOG41080HT	Transcriptional regulator, arsr family
HQR01_06995	ENOG4105D3R	alkyl hydroperoxide reductase
HQR01_07010	ENOG4105KFG	YeeE YedE family protein
HQR01_07020	ENOG4108VCT	Sulfite exporter TauE/SafE
HQR01_07025	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HQR01_07030	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HQR01_07070	ENOG4105BZU	Histidine kinase
HQR01_07075	ENOG4105F7P	transcriptional regulator AsnC family
HQR01_07085	ENOG4107S9D	Alpha beta hydrolase
HQR01_07090	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HQR01_07095	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HQR01_07105	ENOG4105VPX	protein, conserved in bacteria
HQR01_07110	ENOG4105E3B	Multicopper oxidase
HQR01_07130	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HQR01_07145	ENOG4105VIE	preprotein translocase, subunit YajC
HQR01_07150	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HQR01_07155	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HQR01_07160	ENOG4107TYR	Glycosyl Transferase
HQR01_07175	ENOG4105C5H	ABC transporter
HQR01_07180	ENOG4105CD3	dihydroorotase
HQR01_07195	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HQR01_07200	ENOG4105IFJ	Histidine kinase
HQR01_07210	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HQR01_07215	ENOG4105EAH	synthase
HQR01_07220	ENOG4105CPC	Aldo Keto reductase
HQR01_07225	ENOG4105CQ7	ATP-dependent helicase
HQR01_07240	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HQR01_07245	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HQR01_07255	ENOG4105K70	DNA-binding protein
HQR01_07290	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HQR01_07300	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HQR01_07315	ENOG4105CE9	30S ribosomal protein S2
HQR01_07320	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HQR01_07370	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HQR01_07375	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HQR01_07380	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HQR01_07395	ENOG4105DZP	Membrane-associated zinc metalloprotease
HQR01_07410	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HQR01_07415	ENOG41082FS	50S ribosomal protein L31
HQR01_07440	ENOG41060IM	Heme exporter protein
HQR01_07450	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HQR01_07455	ENOG4105DA4	cytochrome c-type biogenesis protein
HQR01_07465	ENOG4105KWW	Biogenesis protein
HQR01_07470	ENOG4106FI7	cytochrome c-type biogenesis protein
HQR01_07475	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HQR01_07480	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HQR01_07485	ENOG4105ETT	transcriptional Regulator, LysR family
HQR01_07490	ENOG4107835	probably involved in intracellular septation (By similarity)
HQR01_07495	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HQR01_07500	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HQR01_07505	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HQR01_07510	ENOG4105BZU	Histidine kinase
HQR01_07520	ENOG4105C7K	acetolactate synthase
HQR01_07545	ENOG4105C5Q	Transcriptional regulator
HQR01_07550	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HQR01_07555	ENOG4105C9M	aspartyl-trna synthetase
HQR01_07570	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HQR01_07575	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HQR01_07580	ENOG4105HHA	aminodeoxychorismate lyase
HQR01_07600	ENOG4105DFP	Integrase
HQR01_07610	ENOG4105E4C	Lytic transglycosylase catalytic
HQR01_07700	ENOG4108UUM	single-stranded DNA-binding protein
HQR01_07720	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HQR01_07730	ENOG4107SQD	Transcriptional regulator, GntR family
HQR01_07745	ENOG4105CAH	Chromate
HQR01_07750	ENOG4108UUM	single-stranded DNA-binding protein
HQR01_07860	ENOG4105C3F	Signal peptidase i
HQR01_07935	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HQR01_07980	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HQR01_07985	ENOG4108IJF	Heavy metal efflux pump, CzcA
HQR01_08000	ENOG4105C5X	domain protein
HQR01_08045	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
HQR01_08065	ENOG4105E3B	Multicopper oxidase
HQR01_08135	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HQR01_08140	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HQR01_08155	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HQR01_08165	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HQR01_08180	ENOG4105CJP	fad dependent oxidoreductase
HQR01_08185	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HQR01_08190	ENOG4105CFQ	glutamine synthetase
HQR01_08200	ENOG4105C5Q	Transcriptional regulator
HQR01_08205	ENOG4108HM4	ABC transporter
HQR01_08215	ENOG4105D38	putrescine abc transporter
HQR01_08220	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HQR01_08225	ENOG4105C26	Dehydrogenase
HQR01_08230	ENOG4108Z86	Glutamine amidotransferase
HQR01_08235	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HQR01_08240	ENOG4105C26	Dehydrogenase
HQR01_08245	ENOG4105CYW	agmatinase
HQR01_08255	ENOG4105CYM	Glutathione S-transferase
HQR01_08265	ENOG4108Q5Y	Membrane
HQR01_08270	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HQR01_08280	ENOG4105DX0	Hemolysin A
HQR01_08285	ENOG4105CFF	transcriptional regulator
HQR01_08305	ENOG4108UKI	Enoyl-CoA hydratase
HQR01_08310	ENOG4108RXX	maleylacetoacetate isomerase
HQR01_08320	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HQR01_08335	ENOG4108Z7R	Chaperone CsaA
HQR01_08340	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
HQR01_08345	ENOG4105DUX	Transporter
HQR01_08350	ENOG4105D49	3-dehydroquinate synthase
HQR01_08355	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HQR01_08365	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HQR01_08370	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HQR01_08390	ENOG4105M6F	mutator MutT protein
HQR01_08405	ENOG4105EUJ	GTP cyclohydrolase i
HQR01_08415	ENOG4105EHV	domain protein
HQR01_08425	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HQR01_08430	ENOG4105I8F	Histidine kinase
HQR01_08435	ENOG4105K8N	protein family UPF0079, ATPase
HQR01_08440	ENOG4105EHM	Aminoglycoside phosphotransferase
HQR01_08445	ENOG4108S0S	Nucleotidyl transferase
HQR01_08455	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HQR01_08465	ENOG4108MWI	inositol mono-phosphatase
HQR01_08480	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HQR01_08485	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HQR01_08500	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HQR01_08505	ENOG4105BZU	Histidine kinase
HQR01_08510	ENOG4108JA2	transcriptioN-repair coupling factor
HQR01_08525	ENOG4105CB5	ATP-dependent DNA helicase recG
HQR01_08530	ENOG4105N14	lysine exporter protein LysE YggA
HQR01_08535	ENOG4105KJF	protein tyrosine phosphatase
HQR01_08550	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HQR01_08555	ENOG4107R0V	Pyruvate dehydrogenase
HQR01_08560	ENOG4105CPP	Dehydrogenase, E1 component
HQR01_08565	ENOG4107QSN	dihydrolipoamide acetyltransferase
HQR01_08590	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HQR01_08605	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HQR01_08615	ENOG4105BZA	Phosphoglycerate kinase
HQR01_08625	ENOG4105WYW	fructose-bisphosphate aldolase
HQR01_08635	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HQR01_08645	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HQR01_08655	ENOG4105ECY	inositol monophosphatase
HQR01_08675	ENOG4105CH2	amidohydrolase
HQR01_08685	ENOG4107RET	Isocitrate lyase
HQR01_08705	ENOG4105BZU	Histidine kinase
HQR01_08710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HQR01_08735	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HQR01_08740	ENOG4105CUB	amino acid
HQR01_08760	ENOG4105C0B	DNA polymerase III (alpha subunit)
HQR01_08765	ENOG410829K	Lysine exporter protein (Lyse ygga)
HQR01_08775	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HQR01_08785	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HQR01_08795	ENOG4105C8U	phosphate abc transporter
HQR01_08805	ENOG4106MAR	Phosphate-selective porin O and P
HQR01_08810	ENOG4105BZU	Histidine kinase
HQR01_08825	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HQR01_08860	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HQR01_08870	ENOG4105CIR	epoxide hydrolase
HQR01_08885	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HQR01_08890	ENOG4108ZP8	Acetolactate synthase small subunit
HQR01_08900	ENOG4105C7K	acetolactate synthase
HQR01_08905	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HQR01_08910	ENOG4105EAC	phosphoserine phosphatase
HQR01_08935	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HQR01_08945	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HQR01_08955	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HQR01_08965	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HQR01_08975	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HQR01_08980	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HQR01_08990	ENOG4105DA5	(ABC) transporter
HQR01_08995	ENOG4105E3A	(ABC) transporter
HQR01_09005	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HQR01_09020	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HQR01_09040	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HQR01_09050	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HQR01_09055	ENOG4108YZG	isomerase
HQR01_09065	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HQR01_09070	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HQR01_09080	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HQR01_09095	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HQR01_09130	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HQR01_09135	ENOG4105C9K	Endothelin-converting enzyme 1
HQR01_09155	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HQR01_09180	ENOG4105CNI	cell division protein FtsW
HQR01_09205	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HQR01_09215	ENOG4108ZMQ	domain protein
HQR01_09230	ENOG4105C3G	gtp-binding protein
HQR01_09235	ENOG4105CHR	reductase
HQR01_09245	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HQR01_09250	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HQR01_09265	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HQR01_09270	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HQR01_09275	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HQR01_09280	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HQR01_09290	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HQR01_09295	ENOG4108Z6Z	Transcriptional regulator
HQR01_09300	ENOG4105CSU	acyl-Coa dehydrogenase
HQR01_09320	ENOG4107Y80	Major Facilitator superfamily
HQR01_09330	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HQR01_09340	ENOG4105EHZ	conserved protein UCP016719
HQR01_09350	ENOG4105DNH	Major Facilitator
HQR01_09355	ENOG4105NX3	Membrane
HQR01_09370	ENOG4108N3W	hemolysin secretion protein
HQR01_09375	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HQR01_09385	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HQR01_09395	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HQR01_09400	ENOG41082FP	UPF0102 protein
HQR01_09405	ENOG4105D7Z	glutathione synthase
HQR01_09410	ENOG4107T5V	SNARE associated Golgi
HQR01_09415	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HQR01_09420	ENOG4105CSA	Coproporphyrinogen iii oxidase
HQR01_09430	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HQR01_09435	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HQR01_09440	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HQR01_09445	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HQR01_09470	ENOG4105CFG	Acts as a chaperone (By similarity)
HQR01_09505	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HQR01_09515	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
HQR01_09520	ENOG4105IIU	Aminopeptidase
HQR01_09525	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HQR01_09550	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HQR01_09570	ENOG4105CVE	Lytic murein transglycosylase
HQR01_09580	ENOG4105DZ1	carboxypeptidase
HQR01_09585	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HQR01_09590	ENOG4107QRG	dna polymerase iii
HQR01_09600	ENOG4105F8V	Hydrolase, tatD family
HQR01_09605	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HQR01_09615	ENOG4105DXN	mazG family
HQR01_09620	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HQR01_09625	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HQR01_09630	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HQR01_09635	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HQR01_09640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HQR01_09645	ENOG4105ES5	Histidine kinase
HQR01_09655	ENOG4105CUX	Signal transduction histidine kinase
HQR01_09665	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HQR01_09670	ENOG4105CEV	competence damage-inducible protein
HQR01_09675	ENOG4108Z1B	Cyclase dehydrase
HQR01_09680	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HQR01_09685	ENOG41077A9	carbonic anhydrase
HQR01_09700	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HQR01_09715	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HQR01_09785	ENOG4108J2P	Alpha beta hydrolase fold
HQR01_09790	ENOG4105EQ0	Major Facilitator superfamily
HQR01_09810	ENOG4105VW4	glutaredoxin 3
HQR01_09815	ENOG4108ZNX	Heat shock protein
HQR01_09820	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HQR01_09830	ENOG4105CP7	Triose-phosphate isomerase
HQR01_09840	ENOG4105CRQ	synthase (Component I)
HQR01_09845	ENOG4108T58	Mg2 transport protein CorA
HQR01_09855	ENOG4105DDQ	anthranilate synthase
HQR01_09860	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HQR01_09865	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HQR01_09870	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HQR01_09875	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HQR01_09880	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HQR01_09885	ENOG4105BZN	citrate synthase
HQR01_09890	ENOG4105BZU	Histidine kinase
HQR01_09920	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HQR01_09925	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HQR01_09930	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HQR01_09935	ENOG4105C8S	subunit m
HQR01_09940	ENOG4105D65	subunit l
HQR01_09945	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HQR01_09950	ENOG4105DF2	NADH dehydrogenase subunit j
HQR01_09955	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HQR01_09960	ENOG4108IZQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HQR01_09980	ENOG4107QIZ	NADH dehydrogenase
HQR01_09995	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HQR01_10005	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HQR01_10010	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HQR01_10015	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HQR01_10025	ENOG4107RGH	Aldehyde dehydrogenase
HQR01_10055	ENOG4105I4A	GCN5-related N-acetyltransferase
HQR01_10070	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HQR01_10075	ENOG4108JQC	penicillin-binding protein 1A
HQR01_10080	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HQR01_10085	ENOG4105C03	ribonuclease
HQR01_10090	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HQR01_10115	ENOG4105D6Z	AFG1 family ATPase
HQR01_10145	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HQR01_10165	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HQR01_10175	ENOG4105C01	Dihydroxy-acid dehydratase
HQR01_10185	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HQR01_10195	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HQR01_10210	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HQR01_10230	ENOG4108R99	pseudouridine synthase
HQR01_10240	ENOG4105CEY	Amp-dependent synthetase and ligase
HQR01_10255	ENOG4108V06	Glutathione peroxidase
HQR01_10270	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HQR01_10275	ENOG4105D60	lipoprotein releasing system transmembrane protein
HQR01_10280	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HQR01_10285	ENOG4105PDP	Short chain dehydrogenase
HQR01_10295	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HQR01_10300	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HQR01_10310	ENOG4105DQU	oxidoreductase, subunit beta
HQR01_10315	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HQR01_10325	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HQR01_10335	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HQR01_10355	ENOG4105CGZ	zinc metallopeptidase
HQR01_10370	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HQR01_10375	ENOG4105D5Q	Arginine ornithine antiporter
HQR01_10420	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HQR01_10430	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
HQR01_10435	ENOG4105CHR	reductase
HQR01_10445	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HQR01_10475	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HQR01_10495	ENOG4105BZU	Histidine kinase
HQR01_10500	ENOG4105BZU	Histidine kinase
HQR01_10505	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQR01_10515	ENOG4105DU1	integral membrane protein, terc
HQR01_10525	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HQR01_10530	ENOG4105II7	pyrroline-5-carboxylate reductase
HQR01_10535	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HQR01_10540	ENOG4108W2P	Methyl-accepting chemotaxis
HQR01_10545	ENOG4107EFQ	arachidonate 15-lipoxygenase
HQR01_10560	ENOG4105F8J	Adenylate Guanylate cyclase
HQR01_10580	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HQR01_10585	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HQR01_10600	ENOG4105EQH	reductase
HQR01_10630	ENOG4105DV0	amidase (EC 3.5.1.4
HQR01_10660	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HQR01_10670	ENOG4105DFU	Cell wall formation (By similarity)
HQR01_10675	ENOG4108K3A	Glutathione S-transferase
HQR01_10680	ENOG4105CKW	Inner membrane protein yedI
HQR01_10685	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HQR01_10690	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HQR01_10695	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HQR01_10700	ENOG4105FYV	Amp nucleosidase
HQR01_10705	ENOG4108KEZ	Dehydrogenase
HQR01_10710	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HQR01_10715	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HQR01_10735	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HQR01_10755	ENOG4105CW7	secretion protein, HlyD family
HQR01_10760	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HQR01_10770	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HQR01_10780	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HQR01_10785	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HQR01_10790	ENOG4105ETT	transcriptional Regulator, LysR family
HQR01_10810	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HQR01_10820	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HQR01_10835	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HQR01_10845	ENOG4105CAT	Cytidine monophosphate kinase
HQR01_10855	ENOG4108R5S	membrane
HQR01_10860	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HQR01_10865	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HQR01_10880	ENOG4108733	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HQR01_10890	ENOG4105VD1	ATP synthase subunit C
HQR01_10895	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HQR01_10920	ENOG4105W5Q	DNA repair protein (RadC
HQR01_10930	ENOG4105C83	adenylosuccinate lyase
HQR01_10940	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HQR01_10950	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HQR01_10955	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HQR01_10960	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HQR01_10965	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HQR01_10970	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HQR01_10980	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
HQR01_10985	ENOG4105FE9	pseudouridine synthase
HQR01_10990	ENOG4106H78	methyltransferase
HQR01_11020	ENOG4105CQB	FAD linked oxidase domain protein
HQR01_11055	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HQR01_11060	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HQR01_11070	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HQR01_11075	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HQR01_11100	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HQR01_11110	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HQR01_11115	ENOG4107SC1	transglycosylase
HQR01_11120	ENOG4108RRZ	Transcription elongation factor GreB
HQR01_11135	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HQR01_11140	ENOG4108RPX	mosc domain containing protein
HQR01_11150	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HQR01_11155	ENOG4108R85	Short chain dehydrogenase
HQR01_11165	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HQR01_11170	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HQR01_11190	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HQR01_11200	ENOG4105HEI	LysR family (Transcriptional regulator
HQR01_11205	ENOG4105CDH	Citrulline--aspartate ligase
HQR01_11210	ENOG4105K6T	rare lipoprotein A
HQR01_11280	ENOG4105C9K	Endothelin-converting enzyme 1
HQR01_11285	ENOG4105BZU	Histidine kinase
HQR01_11290	ENOG4106TD9	Diguanylate cyclase
HQR01_11300	ENOG4105DGW	oligopeptidase A
HQR01_11305	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HQR01_11310	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HQR01_11320	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HQR01_11335	ENOG4105BZU	Histidine kinase
HQR01_11340	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HQR01_11345	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HQR01_11350	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HQR01_11355	ENOG4105C7S	Dehydrogenase
HQR01_11360	ENOG4107QN2	dihydrolipoyl dehydrogenase
HQR01_11370	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HQR01_11380	ENOG4105EN6	Membrane
HQR01_11395	ENOG4108ZT0	50S ribosomal protein l17
HQR01_11400	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HQR01_11405	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HQR01_11410	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HQR01_11425	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HQR01_11430	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HQR01_11435	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HQR01_11445	ENOG41084HQ	50S ribosomal protein L30
HQR01_11450	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HQR01_11455	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HQR01_11460	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HQR01_11465	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HQR01_11470	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HQR01_11475	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HQR01_11480	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HQR01_11485	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HQR01_11490	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HQR01_11495	ENOG41083MP	50s ribosomal protein l29
HQR01_11500	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HQR01_11505	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HQR01_11510	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HQR01_11515	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HQR01_11520	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HQR01_11525	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HQR01_11530	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HQR01_11535	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HQR01_11540	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HQR01_11545	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HQR01_11550	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HQR01_11555	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HQR01_11560	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HQR01_11595	ENOG4105ETT	transcriptional Regulator, LysR family
HQR01_11600	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HQR01_11605	ENOG4105C9X	ppx gppa phosphatase
HQR01_11610	ENOG4105CHH	sulfate transporter
HQR01_11615	ENOG4105NWN	ApaG protein
HQR01_11640	ENOG4108N3W	hemolysin secretion protein
HQR01_11670	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HQR01_11675	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
HQR01_11690	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HQR01_11700	ENOG4105FC8	fad dependent oxidoreductase
HQR01_11715	ENOG4105C1J	atp-dependent rna helicase
HQR01_11730	ENOG41069HH	4-oxalocrotonate tautomerase
HQR01_11740	ENOG4107QP8	phosphohexose isomerase
HQR01_11745	ENOG4105C3F	Signal peptidase i
HQR01_11755	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HQR01_11780	ENOG4105C79	DNA protecting protein DprA
HQR01_11785	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HQR01_11790	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HQR01_11800	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HQR01_11830	ENOG4105CYM	Glutathione S-transferase
HQR01_11900	ENOG4105E3Q	saccharopine dehydrogenase
HQR01_11920	ENOG4105C3M	thioredoxin reductase
HQR01_11925	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HQR01_11945	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HQR01_11965	ENOG4108UQY	Iron-storage protein
HQR01_12000	ENOG4105CD3	dihydroorotase
HQR01_12005	ENOG4105CXT	aspartate transcarbamylase
HQR01_12010	ENOG4105D07	Signal peptide peptidase, SppA
HQR01_12030	ENOG4105PF9	Transcriptional regulator
HQR01_12040	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HQR01_12050	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HQR01_12070	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HQR01_12075	ENOG4105BZU	Histidine kinase
HQR01_12110	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HQR01_12125	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HQR01_12145	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HQR01_12180	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HQR01_12190	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HQR01_12220	ENOG4108XHQ	(2Fe-2S)-binding domain protein
HQR01_12225	ENOG4105MP9	class II Aldolase
HQR01_12245	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HQR01_12250	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HQR01_12255	ENOG4105BZU	Histidine kinase
HQR01_12260	ENOG4105BZU	Histidine kinase
HQR01_12275	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HQR01_12300	ENOG4105CT3	Monooxygenase
HQR01_12305	ENOG4105CEV	competence damage-inducible protein
HQR01_12315	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HQR01_12320	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HQR01_12325	ENOG41087YS	Phage shock protein A
HQR01_12345	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HQR01_12350	ENOG4105PM1	preprotein translocase subunit SecE
HQR01_12370	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HQR01_12385	ENOG4108URH	decarboxylase
HQR01_12390	ENOG4105FE1	phytoene synthase
HQR01_12445	ENOG4105CC9	acyl-Coa dehydrogenase
HQR01_12465	ENOG410616I	blue (type 1) copper domain protein
HQR01_12500	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
HQR01_12535	ENOG4105C59	p-type ATPase
HQR01_12550	ENOG4105D4P	Coproporphyrinogen iii oxidase
HQR01_12555	ENOG4105C26	Dehydrogenase
HQR01_12585	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HQR01_12590	ENOG4105CGU	Enoyl-CoA hydratase
HQR01_12600	ENOG4105E39	Enoyl-CoA hydratase
HQR01_12625	ENOG4106FI7	cytochrome c-type biogenesis protein
HQR01_12630	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HQR01_12645	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HQR01_12675	ENOG4105F8J	Adenylate Guanylate cyclase
HQR01_12680	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQR01_12685	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HQR01_12690	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HQR01_12695	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HQR01_12705	ENOG4105C3R	Methionine synthase
HQR01_12710	ENOG4105C3R	Methionine synthase
HQR01_12715	ENOG4105SYT	Methylenetetrahydrofolate reductase
HQR01_12720	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HQR01_12725	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HQR01_12780	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HQR01_12785	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HQR01_12800	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HQR01_12805	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HQR01_12810	ENOG41076YT	nitrate reductase, gamma subunit
HQR01_12815	ENOG4105R3A	Nitrate reductase
HQR01_12820	ENOG4108IUE	nitrate reductase beta subunit
HQR01_12825	ENOG4105CRU	nitrate reductase, alpha subunit
HQR01_12830	ENOG4105DQQ	Major facilitator superfamily MFS_1
HQR01_12845	ENOG4108V9Q	carbonic anhydrase
HQR01_12855	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HQR01_12875	ENOG4105D7T	ABC transporter
HQR01_12885	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HQR01_12890	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
HQR01_12900	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HQR01_12910	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HQR01_12915	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HQR01_12925	ENOG4105EBR	Carboxylesterase
HQR01_12935	ENOG4105EBR	Carboxylesterase
HQR01_12965	ENOG4105EBR	Carboxylesterase
HQR01_12970	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HQR01_12975	ENOG4105EBR	Carboxylesterase
HQR01_12980	ENOG4105CHU	acetyl-coa acetyltransferase
HQR01_13005	ENOG4105CC9	acyl-Coa dehydrogenase
HQR01_13015	ENOG4105XUA	cytochrome c
HQR01_13045	ENOG4105DND	Transcriptional regulator
HQR01_13050	ENOG4105C2I	pirin domain protein
HQR01_13055	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HQR01_13075	ENOG4105C84	Histidine ammonia-lyase
HQR01_13080	ENOG4105CI2	imidazolone-5-propionate hydrolase
HQR01_13100	ENOG4108JJA	ABC, transporter
HQR01_13115	ENOG4105UYK	outer membrane protein a
HQR01_13120	ENOG4105DFG	type I secretion outer membrane protein
HQR01_13125	ENOG4108JJA	ABC, transporter
HQR01_13135	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HQR01_13150	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HQR01_13155	ENOG4108VZM	50s ribosomal protein L10
HQR01_13170	ENOG4105VMP	Transcriptional regulator
HQR01_13190	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HQR01_13195	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HQR01_13200	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HQR01_13205	ENOG4105BZU	Histidine kinase
HQR01_13220	ENOG4105CA9	Pyruvate kinase
HQR01_13230	ENOG4105Y2X	UPF0335 protein
HQR01_13245	ENOG4105CDY	transcriptional regulatory protein
HQR01_13255	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HQR01_13260	ENOG4105KUZ	arsenate reductase
HQR01_13265	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HQR01_13280	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HQR01_13285	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HQR01_13290	ENOG4105CFH	Aspartokinase
HQR01_13295	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HQR01_13300	ENOG4107QWG	2-Nitropropane dioxygenase
HQR01_13335	ENOG4107QX8	SPFH domain, Band 7 family protein
HQR01_13355	ENOG4105DFP	Integrase
HQR01_13360	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
HQR01_13400	ENOG4105DZR	Type I site-specific deoxyribonuclease
HQR01_13440	ENOG4107R3N	Filamentation induced by cAMP protein fic
HQR01_13450	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HQR01_13460	ENOG41084CK	capsule polysaccharide
HQR01_13470	ENOG4107FW0	short-chain dehydrogenase reductase
HQR01_13485	ENOG4105C2X	Arabinose 5-phosphate isomerase
HQR01_13490	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HQR01_13500	ENOG4105E12	capsule polysaccharide
HQR01_13505	ENOG4105ECX	polysaccharide export
HQR01_13515	ENOG4105EY8	ABC transporter
HQR01_13535	ENOG4105DAY	polysaccharide export protein
HQR01_13565	ENOG4105CMM	transposase
HQR01_13570	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HQR01_13575	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HQR01_13600	ENOG4105DG6	mannose-6-phosphate isomerase
HQR01_13610	ENOG4105C9Q	fumarate hydratase class II
HQR01_13625	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HQR01_13640	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HQR01_13680	ENOG4105E7U	AraC family transcriptional regulator
HQR01_13690	ENOG4108RG0	uracil-dna glycosylase
HQR01_13705	ENOG4108FN7	Aldo keto reductase
HQR01_13710	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HQR01_13715	ENOG4107YFT	Nadph-dependent fmn reductase
HQR01_13725	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HQR01_13735	ENOG4105CHR	reductase
HQR01_13740	ENOG4107RDJ	Sulfotransferase
HQR01_13750	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HQR01_13755	ENOG4105DVW	rieske (2Fe-2S)
HQR01_13770	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HQR01_13775	ENOG4105CI2	imidazolone-5-propionate hydrolase
HQR01_13780	ENOG4105CI0	Citrate lyase
HQR01_13785	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HQR01_13795	ENOG4105DJG	MaoC domain protein dehydratase
HQR01_13825	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HQR01_13830	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HQR01_13840	ENOG4108ZTZ	UPF0262 protein
HQR01_13850	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HQR01_13855	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HQR01_13890	ENOG4105YK5	50S ribosomal protein L36
HQR01_13950	ENOG4105C0P	Mg chelatase subunit ChlI
HQR01_13965	ENOG4105VG0	50S ribosomal protein l34
HQR01_13970	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HQR01_13975	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HQR01_13985	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HQR01_14010	ENOG4108TGY	Glutathione S-transferase
HQR01_14020	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HQR01_14025	ENOG4105CK2	sodium dicarboxylate symporter
HQR01_14030	ENOG4105CSM	endonuclease III
HQR01_14035	ENOG4105EYW	Ion transport protein
HQR01_14045	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HQR01_14050	ENOG4107ZSV	Receptor
HQR01_14055	ENOG4105D06	uba thif-type nad fad binding protein
HQR01_14065	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HQR01_14075	ENOG4105E0X	reductase
HQR01_14080	ENOG4105BZ4	penicillin-binding protein
HQR01_14095	ENOG4107RIZ	hflk protein
HQR01_14105	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HQR01_14110	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HQR01_14125	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HQR01_14140	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HQR01_14150	ENOG4105C4K	Nad synthetase
HQR01_14155	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HQR01_14160	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
HQR01_14195	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HQR01_14220	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HQR01_14230	ENOG4105D2B	acyl-CoA dehydrogenase
HQR01_14235	ENOG4105CC9	acyl-Coa dehydrogenase
HQR01_14250	ENOG4107XAN	XdhC and CoxI family
HQR01_14275	ENOG4105QV4	Tryptophan halogenase
HQR01_14285	ENOG4105CG3	alpha amylase, catalytic region
HQR01_14305	ENOG4105ETE	Transcriptional regulator (LacI family
HQR01_14325	ENOG4105CHU	acetyl-coa acetyltransferase
HQR01_14335	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_14360	ENOG4108I69	Glycosyl transferases group 1
HQR01_14375	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_14390	ENOG41080PD	NADH ubiquinone oxidoreductase 41 kD complex I subunit
HQR01_14400	ENOG4105CP2	von willebrand factor, type a
HQR01_14410	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HQR01_14415	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HQR01_14420	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HQR01_14445	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HQR01_14470	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_14475	ENOG4105CC9	acyl-Coa dehydrogenase
HQR01_14480	ENOG4108RM3	Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo
HQR01_14500	ENOG4105ETE	Transcriptional regulator (LacI family
HQR01_14530	ENOG4105EA8	2-Nitropropane dioxygenase
HQR01_14535	ENOG4105C1G	acyl-Coa dehydrogenase
HQR01_14540	ENOG4105CHR	reductase
HQR01_14545	ENOG4105CPC	Aldo Keto reductase
HQR01_14550	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HQR01_14575	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HQR01_14595	ENOG4105E4C	Lytic transglycosylase catalytic
HQR01_14610	ENOG4105EJX	conjugal transfer ATPase
HQR01_14630	ENOG4108EHY	type IV secretion system
HQR01_14635	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HQR01_14680	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HQR01_14695	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HQR01_14700	ENOG4108TGP	Thioesterase superfamily protein
HQR01_14715	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HQR01_14760	ENOG41087YS	Phage shock protein A
HQR01_14770	ENOG4105E51	psp operon transcriptional activator
HQR01_14775	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HQR01_14800	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HQR01_14820	ENOG4107104	thymidine kinase
HQR01_14830	ENOG4108Z4T	Peptidase M50
HQR01_14835	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HQR01_14840	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HQR01_14845	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HQR01_14865	ENOG4105E3A	(ABC) transporter
HQR01_14880	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HQR01_14960	ENOG4105EAH	synthase
HQR01_15015	ENOG4106KR7	LysR family Transcriptional regulator
HQR01_15025	ENOG4105DTD	Dehydrogenase
HQR01_15040	ENOG4108JA1	polyketide synthase
HQR01_15095	ENOG4105CY0	Metallo-Beta-Lactamase
HQR01_15100	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HQR01_15120	ENOG4105CHB	tonB-dependent Receptor
HQR01_15130	ENOG4107KJX	Transcriptional regulator