locus-tag class description H5C80_00075 ENOG4108SF5 RNA Polymerase H5C80_00080 ENOG4108S3W Anti-feci sigma factor, fecr H5C80_00085 ENOG4105GAV receptor H5C80_00090 ENOG4108HUF Transporter H5C80_00095 ENOG4105DQ5 transport system permease protein H5C80_00100 ENOG4108IHU transport system permease protein H5C80_00105 ENOG4105E0A ABC, transporter H5C80_00120 ENOG4105F9F transposase H5C80_00135 ENOG4108YXQ IS66 Orf2 family protein H5C80_00145 ENOG4105CXY transporter H5C80_00150 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC H5C80_00160 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta H5C80_00180 ENOG4108ZJG MrfB protein H5C80_00185 ENOG4106PG1 outer membrane usher protein H5C80_00190 ENOG4106P2F Pfam:Pili_assembly_C H5C80_00210 ENOG4105CXC rtn protein H5C80_00235 ENOG4105DQ4 alcohol dehydrogenase H5C80_00240 ENOG4105D7A ATP-binding protein H5C80_00245 ENOG4108K5H permease YjgP YjgQ family protein H5C80_00250 ENOG4108M8S permease YjgP YjgQ family protein H5C80_00260 ENOG4105MYG DNA polymerase iii, chi subunit H5C80_00265 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) H5C80_00270 ENOG4108M3P Membrane H5C80_00275 ENOG4108MJ3 acetyltransferase H5C80_00280 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) H5C80_00285 ENOG4105DBV ornithine carbamoyltransferase H5C80_00295 ENOG4105XEP YhcH YjgK YiaL family protein H5C80_00300 ENOG4108XFH Transcriptional regulator H5C80_00305 ENOG4105F6U Short-chain dehydrogenase reductase Sdr H5C80_00310 ENOG4108UQ8 endoribonuclease L-psp H5C80_00315 ENOG4107C93 pyrBI operon leader peptide H5C80_00330 ENOG4105KME endoribonuclease L-psp H5C80_00335 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic H5C80_00345 ENOG4105D4X repressor H5C80_00350 ENOG4105C5Y PTS System H5C80_00355 ENOG4105CG3 alpha amylase, catalytic region H5C80_00360 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase H5C80_00365 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) H5C80_00370 ENOG4108XVM Cytochrome b(562) H5C80_00375 ENOG4105CMS peptidase U62, modulator of DNA gyrase H5C80_00380 ENOG4105N42 UPF0307 protein H5C80_00385 ENOG4105DFU Cell wall formation (By similarity) H5C80_00395 ENOG41062B0 ABC transporter, permease H5C80_00400 ENOG4107R9N ABC transporter H5C80_00405 ENOG4105C2J ABC transporter H5C80_00410 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator H5C80_00415 ENOG4105F0N pyrophosphate phospho-hydrolase H5C80_00420 ENOG4108ZHD aig2 family H5C80_00425 ENOG4105MA0 exported protein H5C80_00430 ENOG4105CFU surface antigen H5C80_00440 ENOG4105C37 (CBS) domain H5C80_00445 ENOG41061GZ Protein of unknown function (DUF1107) H5C80_00450 ENOG4108UUE Transcriptional regulator H5C80_00460 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase H5C80_00465 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic H5C80_00470 ENOG4105KVH Transcriptional regulator H5C80_00475 ENOG4105ECR NmrA family H5C80_00480 ENOG4105DXC membrane H5C80_00505 ENOG4108V1T peptidylprolyl cis-trans isomerase H5C80_00510 ENOG4105FHY Opacity-associated protein A H5C80_00520 ENOG4105CHR reductase H5C80_00530 ENOG4105E39 Enoyl-CoA hydratase H5C80_00535 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) H5C80_00540 ENOG4107S3R L-aspartate oxidase H5C80_00545 ENOG4105DPW Major facilitator superfamily MFS_1 H5C80_00565 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) H5C80_00580 ENOG4105KIT UPF0379 protein yjfY H5C80_00595 ENOG4105H6Q decarboxylase H5C80_00605 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport H5C80_00610 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC H5C80_00625 ENOG4108MXZ Esterase H5C80_00630 ENOG4105WSB biofilm stress and motility protein A H5C80_00635 ENOG4105S17 UPF0379 protein yjfN H5C80_00640 ENOG4105CSU acyl-Coa dehydrogenase H5C80_00645 ENOG4106032 Glutathionylspermidine synthase H5C80_00650 ENOG4108KXT Conserved Protein H5C80_00655 ENOG4105Z6B inner membrane protein yjfl H5C80_00660 ENOG4107VNS Protein of unknown function (DUF2491) H5C80_00665 ENOG4108P9J Phage shock protein A H5C80_00670 ENOG4105FUX Conserved Protein H5C80_00675 ENOG4105C2N RNA methyltransferase TrmH family group 3 H5C80_00680 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) H5C80_00700 ENOG4105EPW hflc protein H5C80_00705 ENOG4107QJR hflk protein H5C80_00710 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) H5C80_00730 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase H5C80_00735 ENOG4105K8N protein family UPF0079, ATPase H5C80_00740 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) H5C80_00785 ENOG4105EGS Mechanosensitive ion channel H5C80_00790 ENOG4106CG8 Inner membrane protein YjeO H5C80_00795 ENOG4106V5W H5C80_00800 ENOG4107SC7 Inner membrane transporter yjeM H5C80_00810 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) H5C80_00815 ENOG4105E33 succinate dehydrogenase H5C80_00830 ENOG41066YJ Beta-lactamase H5C80_00835 ENOG4105QNF Outer membrane lipoprotein H5C80_00840 ENOG4105KPY Small multidrug resistance protein H5C80_00845 ENOG4106BSU Entericidin B H5C80_00850 ENOG4107PEH Entericidin EcnA/B family H5C80_00860 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein H5C80_00865 ENOG4105MTB Uncharacterized protein YjeJ H5C80_00870 ENOG4108ZVF (LipO)protein H5C80_00885 ENOG4105DVH amino acid H5C80_00890 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 H5C80_00895 ENOG4108IJ0 Aspartate ammonia-lyase H5C80_00900 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter H5C80_00910 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) H5C80_00915 ENOG4108SIC Transcriptional regulator H5C80_00925 ENOG4108M3R transcriptional activator CadC H5C80_00930 ENOG4105D5Q Arginine ornithine antiporter H5C80_00935 ENOG4105CXN decarboxylase H5C80_00940 ENOG4105DUX Transporter H5C80_00945 ENOG4105CRK lysyL-tRNA synthetase H5C80_00960 ENOG410830R acetyltransferase H5C80_00965 ENOG4105VR1 Pfam:DUF1271 H5C80_00970 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism H5C80_00975 ENOG4108MRH transcriptional regulatory protein H5C80_00980 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter H5C80_00985 ENOG4107GFK fumarate H5C80_00990 ENOG4108R5S membrane H5C80_00995 ENOG4105CT4 transporter H5C80_01000 ENOG4105F8D glycoside hydrolase family 4 H5C80_01005 ENOG4108K2B transcriptional regulator H5C80_01010 ENOG4105CXN decarboxylase H5C80_01015 ENOG4106ZGR Transcriptional regulator H5C80_01020 ENOG4105D5Q Arginine ornithine antiporter H5C80_01025 ENOG4105DIJ Phosphoethanolamine transferase H5C80_01030 ENOG4105XJC Two component transcriptional regulator (Winged helix family H5C80_01035 ENOG4105ECM Sensor protein basS pmrB H5C80_01045 ENOG4105CSH Transporter H5C80_01050 ENOG4108YIV H5C80_01055 ENOG4108F5E vimentin H5C80_01060 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA H5C80_01065 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase H5C80_01070 ENOG4105D5T phosphonate abc transporter H5C80_01075 ENOG4105EHI Phosphonate ABC transporter, periplasmic H5C80_01085 ENOG4107RJJ Transcriptional regulator H5C80_01090 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG H5C80_01095 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH H5C80_01100 ENOG4105EKV Phosphonate metabolism protein H5C80_01105 ENOG4105FT8 Phosphonate metabolism H5C80_01110 ENOG4105ENV phosphonate C-P lyase system protein PhnK H5C80_01115 ENOG4105HRV phosphonate c-p lyase system protein phnl H5C80_01120 ENOG4105FD8 phosphonate metabolism protein PhnM H5C80_01130 ENOG410849A acetyltransferase, (GNAT) family H5C80_01135 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein H5C80_01145 ENOG4108YZG isomerase H5C80_01150 ENOG4105NYY transcriptional regulator, RpiR H5C80_01155 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator H5C80_01160 ENOG4105C2J ABC transporter H5C80_01165 ENOG4105CNN ABC, transporter H5C80_01170 ENOG4105UP7 3-epimerase H5C80_01175 ENOG4107TFG D-allose kinase H5C80_01180 ENOG4105EUZ Beta-lactamase domain protein H5C80_01190 ENOG4105J12 Multidrug resistance protein mdtN H5C80_01195 ENOG4108MI0 Resistance protein H5C80_01200 ENOG4105ETP RND efflux system, outer membrane lipoprotein H5C80_01210 ENOG41082ND Uncharacterized protein yjcO H5C80_01215 ENOG4105CK2 sodium dicarboxylate symporter H5C80_01220 ENOG4108W0S formate-dependent nitrite reductase complex H5C80_01230 ENOG4108QKW cytochrome c-type biogenesis protein H5C80_01235 ENOG4105DVI reductase, NrfD H5C80_01240 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein H5C80_01245 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit H5C80_01255 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) H5C80_01260 ENOG41062QD Membrane H5C80_01270 ENOG4105EEQ Na H antiporter H5C80_01275 ENOG4105C7N Xanthine uracil vitamin C permease H5C80_01280 ENOG4108Z4X TRANSCRIPTIONal H5C80_01285 ENOG4108W3Q Transcriptional regulator H5C80_01290 ENOG4108M8H domain protein H5C80_01295 ENOG4105PMV Membrane H5C80_01300 ENOG4108UUM single-stranded DNA-binding protein H5C80_01305 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) H5C80_01310 ENOG4105MSB protein, conserved in bacteria H5C80_01315 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme H5C80_01320 ENOG4105F0S class B acid phosphatase H5C80_01330 ENOG4105CGF Aromatic amino acid aminotransferase H5C80_01335 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) H5C80_01340 ENOG4105CDU Replicative dna helicase H5C80_01345 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein H5C80_01350 ENOG4105P4Z Phage shock protein G H5C80_01355 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) H5C80_01365 ENOG4106FE3 DNA repair H5C80_01370 ENOG4105PTU response to oxidative stress H5C80_01375 ENOG4105Y9F tail fiber protein H5C80_01380 ENOG4105Y0G tail protein H5C80_01385 ENOG4108T86 baseplate J family protein H5C80_01405 ENOG4108NKR DNA circulation protein H5C80_01430 ENOG4105TKZ Tail Sheath H5C80_01480 ENOG4105CAR Terminase, large subunit H5C80_01505 ENOG4105NVB glycoside hydrolase, family 19 H5C80_01525 ENOG4105HGD Antitermination protein H5C80_01530 ENOG4108MXB Protein of unknown function (DUF968) H5C80_01540 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) H5C80_01570 ENOG4108S1U H5C80_01605 ENOG4105H40 H5C80_01610 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) H5C80_01615 ENOG4108R7K Metal Dependent Phosphohydrolase H5C80_01620 ENOG41077V0 CPS-53 (KpLE1) prophage H5C80_01655 ENOG4105MYN Zinc uptake regulation protein H5C80_01660 ENOG4105VDW Csbd family H5C80_01665 ENOG4107R73 Mate efflux family protein H5C80_01675 ENOG41080IJ Diacylglycerol kinase H5C80_01695 ENOG4107W52 maltose operon periplasmic protein H5C80_01705 ENOG4108IJ9 (ABC) transporter H5C80_01710 ENOG4107FKK extracellular solute-binding protein family 1 H5C80_01715 ENOG4105D56 permease protein H5C80_01720 ENOG4105EG2 ABC transporter, permease H5C80_01735 ENOG4105E3R (LipO)protein H5C80_01740 ENOG4108Q9C Periplasmic Protein H5C80_01745 ENOG4108MDC (LipO)protein H5C80_01755 ENOG4107QP8 phosphohexose isomerase H5C80_01760 ENOG4105CFH Aspartokinase H5C80_01765 ENOG4108ZR5 Conserved Protein H5C80_01770 ENOG4105FE9 pseudouridine synthase H5C80_01775 ENOG4105DKT Transcriptional regulator H5C80_01780 ENOG4105CHR reductase H5C80_01785 ENOG4108XCU pts system H5C80_01790 ENOG4105KPI PTS system sorbose subfamily IIB component H5C80_01795 ENOG4105ETZ PTS System H5C80_01800 ENOG4105F3R pts system mannose fructose sorbose family iid H5C80_01805 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein H5C80_01815 ENOG4105EAM Na Pi-cotransporter H5C80_01820 ENOG4105C3R Methionine synthase H5C80_01825 ENOG41069M3 Transcriptional regulator H5C80_01835 ENOG4108I9X Isocitrate lyase H5C80_01840 ENOG4107QP3 malate synthase g H5C80_01850 ENOG4105K5X acetyltransferase H5C80_01880 ENOG4105C12 Phosphoribosylglycinamide synthetase H5C80_01885 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family H5C80_01890 ENOG4105BZU Histidine kinase H5C80_01895 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism H5C80_01900 ENOG4108T8B Protein of unknown function (DUF1481) H5C80_01910 ENOG4105R2J Conserved Protein H5C80_01945 ENOG4105D06 uba thif-type nad fad binding protein H5C80_01950 ENOG4105WHD thiamine biosynthesis protein ThiS H5C80_01960 ENOG4105D41 biosynthesis protein thiH H5C80_01995 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) H5C80_02000 ENOG4105PM1 preprotein translocase subunit SecE H5C80_02035 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase H5C80_02080 ENOG4108Y73 Membrane H5C80_02085 ENOG4105EJ2 Transcriptional regulator H5C80_02095 ENOG4105C5Q Transcriptional regulator H5C80_02100 ENOG4108I5G Major Facilitator superfamily H5C80_02105 ENOG4105CXK mandelate racemase muconate lactonizing H5C80_02120 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase H5C80_02135 ENOG4105DIJ Phosphoethanolamine transferase H5C80_02140 ENOG4106R3P AraC family transcriptional regulator H5C80_02145 ENOG4108XCZ PTS System H5C80_02150 ENOG4108AHH pyruvate formate lyase II activase H5C80_02160 ENOG4108YRF PTS System H5C80_02165 ENOG4105DM4 PTS System H5C80_02170 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) H5C80_02175 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) H5C80_02180 ENOG4105DCT glycerol dehydrogenase H5C80_02185 ENOG4108XC3 NADH ubiquinone oxidoreductase H5C80_02190 ENOG4108Q5Y Membrane H5C80_02200 ENOG4105SYT Methylenetetrahydrofolate reductase H5C80_02205 ENOG4105CGH 5'-nucleotidase H5C80_02215 ENOG4105CGH 5'-nucleotidase H5C80_02220 ENOG4105CGH 5'-nucleotidase H5C80_02225 ENOG4105DRB nucleoside-specific channel-forming protein H5C80_02230 ENOG4105CFH Aspartokinase H5C80_02235 ENOG4105C28 cystathionine H5C80_02245 ENOG4107S01 Repressor protein MetJ H5C80_02255 ENOG4105C25 Primosomal protein n' H5C80_02260 ENOG4105ETE Transcriptional regulator (LacI family H5C80_02265 ENOG41063M6 Cell Division Protein H5C80_02280 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase H5C80_02295 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) H5C80_02305 ENOG4105CBT Fructose-1,6-bisphosphatase H5C80_02310 ENOG4105DP0 ferredoxin-NADP reductase H5C80_02320 ENOG41065TG regulatoR H5C80_02325 ENOG4108VTS Membrane H5C80_02330 ENOG4105EBK exported protein H5C80_02345 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein H5C80_02365 ENOG4105ZTC transcriptional activator, Ogr delta H5C80_02405 ENOG4108C33 Resolvase H5C80_02415 ENOG4105PTU response to oxidative stress H5C80_02420 ENOG4108US3 tail fiber assembly H5C80_02515 ENOG4105ED4 portal protein H5C80_02530 ENOG4105NI8 Cytosine-specific methyltransferase H5C80_02535 ENOG4105VZ1 Replication Protein H5C80_02575 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) H5C80_02580 ENOG4105FMW periplasmic H5C80_02585 ENOG4105E3W Two component transcriptional regulator (Winged helix family H5C80_02590 ENOG4105E0F Histidine kinase H5C80_02595 ENOG4108RPX mosc domain containing protein H5C80_02605 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) H5C80_02630 ENOG4105DKG l-rhamnose isomerase H5C80_02650 ENOG4108V87 frv operon regulatory protein H5C80_02655 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) H5C80_02665 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein H5C80_02670 ENOG4108MG3 formate dehydrogenase H5C80_02690 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system H5C80_02700 ENOG4105SUU thioesterase domain H5C80_02715 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 H5C80_02725 ENOG4105CSH Transporter H5C80_02735 ENOG4105CPQ Dehydrogenase H5C80_02740 ENOG4105D2M Aldolase H5C80_02745 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase H5C80_02750 ENOG4108MGF sugar kinase H5C80_02755 ENOG4105E98 transcriptional regulator DeoR family H5C80_02760 ENOG4105R9B Major Facilitator H5C80_02765 ENOG4108KHF Resistance protein H5C80_02770 ENOG4108K85 Transcriptional regulator H5C80_02775 ENOG4105CI3 gtp-binding protein typa H5C80_02780 ENOG4105C5F glutamine synthetase H5C80_02785 ENOG4105CUX Signal transduction histidine kinase H5C80_02790 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family H5C80_02795 ENOG4106FIY H5C80_02800 ENOG4105D4P Coproporphyrinogen iii oxidase H5C80_02815 ENOG4105C2M dna polymerase I H5C80_02820 ENOG4106HNH Acyl-transferase H5C80_02830 ENOG4108Z33 Thiol disulfide Interchange Protein H5C80_02835 ENOG4105E27 serine threonine protein kinase H5C80_02840 ENOG4105PC1 Conserved Protein H5C80_02845 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) H5C80_02850 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b H5C80_02880 ENOG4108RR8 protoporphyrinogen oxidase H5C80_02885 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) H5C80_02890 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein H5C80_02905 ENOG4105CHU acetyl-coa acetyltransferase H5C80_02910 ENOG4108EX3 reductase H5C80_02915 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) H5C80_02920 ENOG4105MDZ Transcriptional activator rfaH H5C80_02930 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) H5C80_02935 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) H5C80_02940 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) H5C80_02950 ENOG4105JC1 sterol-binding domain protein H5C80_02960 ENOG4105CGY Dna recombination protein H5C80_02965 ENOG4107HP6 Transcriptional regulator H5C80_02970 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 H5C80_02975 ENOG4108RTU Aldolase H5C80_02980 ENOG4105JN3 extra-cytoplasmic solute receptor family protein H5C80_02995 ENOG4108I5U Uridine phosphorylase H5C80_03000 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) H5C80_03005 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) H5C80_03015 ENOG4107R1Q Membrane protein FdrA H5C80_03020 ENOG4107REC cytoplasmic protein H5C80_03025 ENOG4105C5B carbamate kinase H5C80_03035 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin H5C80_03040 ENOG4105F52 Transcriptional regulator H5C80_03045 ENOG4106KNT transcriptional regulator H5C80_03050 ENOG4105CV1 Transketolase (EC 2.2.1.1) H5C80_03070 ENOG4105DZ2 Transcriptional regulator H5C80_03075 ENOG4105EMK carboxylate amino acid amine transporter H5C80_03080 ENOG4105DQF Hydrolase H5C80_03085 ENOG4108EUD Lysophospholipase H5C80_03090 ENOG410829K Lysine exporter protein (Lyse ygga) H5C80_03095 ENOG4105CCF Lysine exporter protein (Lyse ygga) H5C80_03100 ENOG4105C9U ATP-dependent DNA helicase RecQ H5C80_03105 ENOG4105HDD phospholipase H5C80_03110 ENOG4108VUY thioesterase Superfamily protein H5C80_03115 ENOG4105FR1 rard protein H5C80_03130 ENOG4107QUT magnesium and cobalt transport protein CorA H5C80_03135 ENOG4108T58 Mg2 transport protein CorA H5C80_03140 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase H5C80_03145 ENOG4105C4R Atp-dependent dna helicase H5C80_03150 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant H5C80_03160 ENOG4105CT0 Protein of unknown function, DUF484 H5C80_03170 ENOG4105S7Z (LipO)protein H5C80_03190 ENOG4107T0K Adenylate cyclase H5C80_03200 ENOG41076E6 Uroporphyrinogen-III Synthase H5C80_03205 ENOG4105ECF c-methyltransferase H5C80_03210 ENOG410601J HemY protein H5C80_03215 ENOG4105ENH Sulfatase H5C80_03220 ENOG4105C4X radical SAM domain protein H5C80_03245 ENOG4105C85 amino acid H5C80_03265 ENOG4105EGZ biosynthesis protein H5C80_03270 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase H5C80_03275 ENOG4108WJ1 acetyltransferase H5C80_03280 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) H5C80_03285 ENOG4105C1B dTDP-glucose 4-6-dehydratase H5C80_03290 ENOG4107QQG Dehydrogenase H5C80_03295 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase H5C80_03300 ENOG4105SFE lipopolysaccharide biosynthesis protein H5C80_03305 ENOG4105ESV Glycosyl transferase, family 4 H5C80_03310 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) H5C80_03335 ENOG4105C4R Atp-dependent dna helicase H5C80_03340 ENOG4105KQ5 peptidylprolyl cis-trans isomerase H5C80_03350 ENOG4105EMY transcriptional regulator H5C80_03355 ENOG4105C7B Threonine dehydratase H5C80_03365 ENOG4105CM2 brancheD-chain amino acid aminotransferase H5C80_03370 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit H5C80_03390 ENOG4105C0P Mg chelatase subunit ChlI H5C80_03395 ENOG4108WFC UPF0438 protein yifE H5C80_03435 ENOG4107EJG GntR family transcriptional regulator H5C80_03440 ENOG4105C0R drug resistance transporter emrb qaca subfamily H5C80_03445 ENOG4105ETE Transcriptional regulator (LacI family H5C80_03450 ENOG4108RVA ribokinase H5C80_03455 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator H5C80_03460 ENOG4105CNN ABC, transporter H5C80_03465 ENOG4105C2J ABC transporter H5C80_03485 ENOG4105EV2 VWA domain protein interacting with AAA ATPase H5C80_03495 ENOG4108VVK transcriptional Regulator, AsnC H5C80_03500 ENOG4105QTB Flavodoxin H5C80_03515 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation H5C80_03565 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) H5C80_03570 ENOG4108RQP Major type 1 subunit fimbrin H5C80_03580 ENOG4105CW0 outer membrane usher protein H5C80_03590 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) H5C80_03595 ENOG4105C8U phosphate abc transporter H5C80_03600 ENOG4105E2Z phosphate ABC transporter (Permease H5C80_03605 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) H5C80_03610 ENOG4108UTW Plays a role in the regulation of phosphate uptake H5C80_03615 ENOG4105CID antiterminator H5C80_03620 ENOG4105C5Y PTS System H5C80_03625 ENOG4105CS2 ec 3.2.1.21 H5C80_03635 ENOG4105DYC esterase H5C80_03640 ENOG4107VKM 6-phosphogluconolactonase H5C80_03650 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 H5C80_03655 ENOG4105C7N Xanthine uracil vitamin C permease H5C80_03660 ENOG4108YYH Nadph-dependent fmn reductase H5C80_03665 ENOG4105E8Q phosphopantetheinyl transferase H5C80_03670 ENOG4105G2Y Transcriptional regulator H5C80_03680 ENOG4108P6C Tryptophan transporter of low affinity H5C80_03695 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) H5C80_03715 ENOG4105VG0 50S ribosomal protein l34 H5C80_03730 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) H5C80_03740 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) H5C80_03745 ENOG4105VP5 Bacterial protein of unknown function (DUF937) H5C80_03750 ENOG410667J hydrolase H5C80_03755 ENOG410657R replicase EC 2.7 H5C80_03760 ENOG4105EMF GntR family transcriptional regulator H5C80_03765 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 H5C80_03770 ENOG4108RTU Aldolase H5C80_03780 ENOG4105DJB Major Facilitator Superfamily H5C80_03785 ENOG4107WAP fad NAD(P)-binding domain H5C80_03790 ENOG4105D99 atp gtp-binding protein H5C80_03795 ENOG4105R2A (LipO)protein H5C80_03815 ENOG4108AHD Transcriptional regulator H5C80_03820 ENOG4107RUZ Sss sodium solute transporter superfamily H5C80_03825 ENOG4105CBG Sulfatase H5C80_03830 ENOG4105VG5 Membrane H5C80_03835 ENOG4105JP4 Inner membrane protein yidG H5C80_03840 ENOG4105J13 transcriptional regulator H5C80_03845 ENOG4105E5M Multidrug resistance protein D H5C80_03860 ENOG4105C7K acetolactate synthase H5C80_03865 ENOG4105M71 acetolactate synthase 1 regulatory subunit H5C80_03870 ENOG4108KX4 response regulator H5C80_03875 ENOG4105BZU Histidine kinase H5C80_03880 ENOG4105CXY transporter H5C80_03885 ENOG4105CXY transporter H5C80_03895 ENOG4105C7N Xanthine uracil vitamin C permease H5C80_03900 ENOG4108SAJ Protein of unknown function (DUF1198) H5C80_03905 ENOG4107RTG Major Facilitator superfamily H5C80_03910 ENOG4105T8A Uncharacterized protein YicS H5C80_03915 ENOG4105D01 (LipO)protein H5C80_03920 ENOG4108UZ3 Transporter H5C80_03940 ENOG4105CT4 transporter H5C80_03945 ENOG4105CJQ hydrolase, family 31 H5C80_03950 ENOG4105ETD TRANSCRIPTIONal H5C80_03955 ENOG4105DM4 PTS System H5C80_03960 ENOG4108YRF PTS System H5C80_03965 ENOG4105DM4 PTS System H5C80_03970 ENOG4105D2N Aldolase H5C80_03980 ENOG4105DKQ ROK family H5C80_03990 ENOG4105JV1 AsmA family H5C80_03995 ENOG4105C2W permease H5C80_04000 ENOG4105D6U Sodium Glutamate Symporter H5C80_04005 ENOG4105CB5 ATP-dependent DNA helicase recG H5C80_04010 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase H5C80_04015 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) H5C80_04025 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) H5C80_04035 ENOG4105EN6 Membrane H5C80_04040 ENOG4105DSJ YicC domain protein H5C80_04060 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) H5C80_04065 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase H5C80_04075 ENOG4105KDC 50s ribosomal protein l28 H5C80_04095 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase H5C80_04100 ENOG4105DKP glycosyl transferase, family 9 H5C80_04105 ENOG4107RJ7 Glycosyl transferase (Group 1 H5C80_04110 ENOG4107543 (lipo)polysaccharide H5C80_04115 ENOG4106AH0 Glycosyl Transferase H5C80_04130 ENOG4105X1N Glycosyl transferase family 8 H5C80_04140 ENOG41068PG O-Antigen polymerase H5C80_04145 ENOG4105D16 lipopolysaccharide heptosyltransferase i H5C80_04150 ENOG4105XA0 heptosyltransferase ii H5C80_04160 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) H5C80_04170 ENOG4105K64 Glycosyl transferase, family 2 H5C80_04175 ENOG4105PXI polysaccharide deacetylase H5C80_04180 ENOG41063SB peptidase H5C80_04190 ENOG4107YZP Rhodanese domain protein H5C80_04195 ENOG4105VW4 glutaredoxin 3 H5C80_04210 ENOG4105D7W serine acetyltransferase H5C80_04215 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) H5C80_04225 ENOG41073TP transcriptional regulator H5C80_04230 ENOG4105DAA L-lactate H5C80_04240 ENOG4108WY4 inner membrane lipoprotein H5C80_04245 ENOG4108YYI Protein of unknown function (DUF2810) H5C80_04250 ENOG41060ND LF82 chromosome, complete sequence H5C80_04255 ENOG4105E61 Mannitol repressor protein H5C80_04265 ENOG4105CTS PTS system mannitol-specific H5C80_04270 ENOG4105FP6 Protein of unknown function (DUF3302) H5C80_04275 ENOG4105EFX secretion protein, HlyD family H5C80_04280 ENOG4108U78 Glutathione S-transferase H5C80_04290 ENOG4105EM7 Selenocysteine-specific translation elongation factor H5C80_04295 ENOG4105C0A alcohol dehydrogenase H5C80_04300 ENOG4105C26 Dehydrogenase H5C80_04310 ENOG4105KK7 inner membrane protein YiaW H5C80_04315 ENOG4105EFX secretion protein, HlyD family H5C80_04320 ENOG4108Q2M Transcriptional regulator H5C80_04325 ENOG4105GNX MltA-interacting MipA family protein H5C80_04335 ENOG4105CT4 transporter H5C80_04345 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase H5C80_04350 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase H5C80_04355 ENOG4105H6Q decarboxylase H5C80_04360 ENOG4105CMG Carbohydrate kinase H5C80_04365 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit H5C80_04370 ENOG4105CG6 trap dicarboxylate transporter dctm subunit H5C80_04375 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter H5C80_04380 ENOG4108R66 Conserved Protein H5C80_04390 ENOG4105J4Q Transcriptional regulator H5C80_04395 ENOG4108XIB electron transport protein ysaA H5C80_04400 ENOG4105JKW Valine--pyruvate aminotransferase H5C80_04405 ENOG4107T9C Alpha amylase catalytic region H5C80_04410 ENOG4108UR8 BAX protein H5C80_04415 ENOG4105T16 Transcriptional regulator (AraC family) H5C80_04420 ENOG4108HWW ABC transporter H5C80_04430 ENOG4105DFW ABC transporter H5C80_04440 ENOG4105CMG Carbohydrate kinase H5C80_04445 ENOG410688U Inner membrane protein yiaB H5C80_04450 ENOG4108Z12 YiaAB two helix domain-containing protein H5C80_04455 ENOG4105MEV Acyl-transferase H5C80_04475 ENOG41060TC Hok gef cell toxic protein H5C80_04485 ENOG4105MVF Transcriptional regulator H5C80_04490 ENOG4106JH6 (LipO)protein H5C80_04495 ENOG4105C5I Dehydrogenase H5C80_04500 ENOG4108ZG0 Ompa motb domain protein H5C80_04505 ENOG4107QY8 reductase H5C80_04510 ENOG4105HNP -acetyltransferase H5C80_04515 ENOG4108R3E Dna-3-methyladenine glycosylase i H5C80_04520 ENOG4105EAX Putative lipase H5C80_04525 ENOG4105FCD Major Facilitator H5C80_04530 ENOG4105DIJ Phosphoethanolamine transferase H5C80_04555 ENOG4105DEF Extracellular solute-binding protein, family 5 H5C80_04565 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component H5C80_04570 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component H5C80_04575 ENOG4105C3U ABC transporter H5C80_04580 ENOG4108JQ7 (ABC) transporter H5C80_04585 ENOG4105C44 Serine transporter H5C80_04610 ENOG4105D1V cellulose synthase operon protein YhjU H5C80_04615 ENOG4105WQA Cellulose biosynthesis protein BcsF H5C80_04620 ENOG4105U74 cellulose biosynthesis protein BcsE H5C80_04625 ENOG410661M cytoplasmic protein H5C80_04635 ENOG4107QZ7 Cellulose synthase catalytic subunit H5C80_04640 ENOG4107EEX Cellulose synthase regulator protein H5C80_04645 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) H5C80_04650 ENOG4105EJG cellulose synthase H5C80_04655 ENOG4105BZU Histidine kinase H5C80_04665 ENOG4105CS0 peptidase H5C80_04670 ENOG4107SS6 2-dehydro-3-deoxygluconokinase H5C80_04675 ENOG4105CMB EAL domain-containing protein H5C80_04680 ENOG41066T0 asmA family H5C80_04685 ENOG4105CSH Transporter H5C80_04690 ENOG4107H3J ribonuclease H5C80_04695 ENOG4105CBN LysR family transcriptional regulator H5C80_04700 ENOG4106S2D Transcriptional regulator H5C80_04710 ENOG4105CA0 peroxidase H5C80_04715 ENOG4105CVK Glutamate decarboxylase H5C80_04730 ENOG4105BZS acriflavin resistance protein H5C80_04735 ENOG4105C1P efflux transporter, rnd family, mfp subunit H5C80_04745 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci H5C80_04750 ENOG4108YK4 Acid-resistance membrane protein H5C80_04755 ENOG41060V2 Acid-resistance protein H5C80_04760 ENOG4105XXV Acid-resistance protein H5C80_04765 ENOG4105KT7 mgtC SapB transporter H5C80_04770 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) H5C80_04775 ENOG4105EHG Permease protein H5C80_04785 ENOG41090JE Utilization Protein H5C80_04790 ENOG4105D4P Coproporphyrinogen iii oxidase H5C80_04795 ENOG4107R4I Periplasmic binding protein H5C80_04800 ENOG4107ENK receptor H5C80_04805 ENOG4106QJH hemin transport protein H5C80_04815 ENOG4105Y4Z Outer Membrane Lipoprotein H5C80_04835 ENOG4105K89 arsenate reductase H5C80_04840 ENOG4107R5R arsenical pump membrane protein H5C80_04845 ENOG4105KBH arsR family transcriptional regulator H5C80_04860 ENOG4105DC8 reductase H5C80_04865 ENOG4105D6S protein involved in catabolism of external DNA H5C80_04870 ENOG4105DGW oligopeptidase A H5C80_04880 ENOG4105DUX Transporter H5C80_04895 ENOG4105CJ3 phosphate transporter H5C80_04900 ENOG4105CBX hi0933 family H5C80_04905 ENOG4107UNS conserved inner membrane protein H5C80_04910 ENOG4105D0S secretion protein (HlyD H5C80_04915 ENOG4105CJ1 ABC, transporter H5C80_04920 ENOG4105CMI transporter H5C80_04940 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) H5C80_04945 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) H5C80_04950 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component H5C80_04955 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component H5C80_04960 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein H5C80_04965 ENOG4107YAK holo-(acyl carrier protein) synthase 2 H5C80_04970 ENOG4105DSF transport protein H5C80_04975 ENOG4105F9N Major Facilitator Superfamily H5C80_04980 ENOG4108W1V Lipoprotein H5C80_04985 ENOG4105EX9 Membrane H5C80_05000 ENOG4107FS9 Membrane H5C80_05010 ENOG4105MG3 Membrane H5C80_05015 ENOG4106H78 methyltransferase H5C80_05020 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) H5C80_05025 ENOG4105CAK Cell division ATP-binding protein ftsE H5C80_05030 ENOG4105CRP Part of the ABC transporter FtsEX involved in H5C80_05035 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) H5C80_05040 ENOG4105CP9 extracellular ligand-binding receptor H5C80_05045 ENOG4105U59 -acetyltransferase H5C80_05050 ENOG4105CP9 extracellular ligand-binding receptor H5C80_05055 ENOG4105C32 Amino acid ABC transporter (Permease) H5C80_05060 ENOG4105CF8 branched-chain amino acid ABC transporter, permease H5C80_05065 ENOG4105C0Z ABC transporter H5C80_05070 ENOG4108IV0 ABC, transporter H5C80_05075 ENOG41060M8 Pfam:PhdYeFM H5C80_05085 ENOG4105BZ7 extracellular solute-binding protein family 1 H5C80_05090 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component H5C80_05095 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component H5C80_05105 ENOG4107T6V glycerophosphoryl diester phosphodiesterase H5C80_05110 ENOG4105WC8 Conserved Protein H5C80_05115 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) H5C80_05120 ENOG4105WCN acetyltransferase H5C80_05125 ENOG4105D9R oxidoreductase H5C80_05130 ENOG4105C2I pirin domain protein H5C80_05135 ENOG4105DIQ Transcriptional regulator H5C80_05140 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family H5C80_05145 ENOG4105C6Z Gluconate H5C80_05150 ENOG41076UM multiple antibiotic resistance (MarC)-related protein H5C80_05155 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) H5C80_05160 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) H5C80_05180 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) H5C80_05190 ENOG4108NAE Fimbrial chaperone protein H5C80_05195 ENOG4105CW0 outer membrane usher protein H5C80_05205 ENOG4108RQP Major type 1 subunit fimbrin H5C80_05210 ENOG4108AF8 Chaperone H5C80_05215 ENOG4105MHR Fimbrial protein H5C80_05235 ENOG4105C6V Glycerol-3-phosphate dehydrogenase H5C80_05250 ENOG4105E98 transcriptional regulator DeoR family H5C80_05255 ENOG4105CYB regulatoR H5C80_05260 ENOG4105E0Y RtcB Protein H5C80_05275 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) H5C80_05280 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) H5C80_05285 ENOG4105C6Z Gluconate H5C80_05295 ENOG4105MJ2 Competence protein H5C80_05305 ENOG4105DNE Transposase H5C80_05315 ENOG4105CE1 Ferrous iron transport protein b H5C80_05320 ENOG4105XFK Ferrous iron transport protein A H5C80_05325 ENOG4105BZM domain protein H5C80_05330 ENOG4108RRZ Transcription elongation factor GreB H5C80_05340 ENOG4105E0F Histidine kinase H5C80_05360 ENOG4108MAJ Membrane H5C80_05370 ENOG4105VEJ Heat shock protein H5C80_05375 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 H5C80_05380 ENOG4105DQY intracellular growth attenuator H5C80_05385 ENOG4107RK2 ADP-ribose diphosphatase NudE H5C80_05390 ENOG4108JQC penicillin-binding protein 1A H5C80_05395 ENOG4108U1Q Pilus assembly protein H5C80_05400 ENOG41065NF Fimbrial assembly family protein H5C80_05405 ENOG4105XPX DNA utilization protein HofO H5C80_05410 ENOG4105ITY Required for the use of extracellular DNA as a nutrient H5C80_05415 ENOG4105E4G Type IV pilus H5C80_05430 ENOG4105EGB membrane protein DamX H5C80_05435 ENOG4105DFE Dna adenine methylase H5C80_05440 ENOG4105DJV ribulose-phosphate 3-epimerase H5C80_05445 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) H5C80_05450 ENOG4105C31 Tryptophanyl-tRNA synthetase H5C80_05455 ENOG4108M21 H5C80_05460 ENOG4105RMW regulation of transcription, DNA-dependent H5C80_05465 ENOG4108626 Racemase H5C80_05470 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) H5C80_05475 ENOG41080QX K07048 phosphotriesterase-related protein H5C80_05480 ENOG4105MUZ Protein of unknown function DUF2620 H5C80_05485 ENOG4106M0N transport system permease protein H5C80_05490 ENOG4106PKC pyridoxal phosphate binding H5C80_05495 ENOG4105VYH H5C80_05505 ENOG4107V9H nitrite transporter H5C80_05510 ENOG4105WZK nitrite reductase NADPH small subunit H5C80_05515 ENOG4107QZF nitrite reductase NADPH large subunit H5C80_05525 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) H5C80_05535 ENOG4105MZU cell filamentation protein H5C80_05540 ENOG4105DDQ anthranilate synthase H5C80_05545 ENOG4105C8Y Acetylornithine aminotransferase H5C80_05550 ENOG410613R integral membrane protein, YccS YhfK family H5C80_05560 ENOG4108UKZ OsmC family H5C80_05565 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) H5C80_05575 ENOG4105DNZ Alpha Beta Hydrolase H5C80_05580 ENOG4105C5H ABC transporter H5C80_05595 ENOG4105VKU nucleicacid-binding protein H5C80_05600 ENOG4108YZY peptidylprolyl cis-trans isomerase H5C80_05610 ENOG4108V1T peptidylprolyl cis-trans isomerase H5C80_05615 ENOG4105WWK YheO domain protein H5C80_05630 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) H5C80_05655 ENOG4108NNZ chitinase H5C80_05660 ENOG4105W53 bacterioferritin-associated ferredoxin H5C80_05665 ENOG4108UQY Iron-storage protein H5C80_05670 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) H5C80_05680 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) H5C80_05685 ENOG4105R04 type II secretion system protein K H5C80_05700 ENOG41069X0 general secretion pathway protein h H5C80_05705 ENOG4108VAU general secretion pathway protein G H5C80_05710 ENOG4105D7Q type ii secretion system H5C80_05715 ENOG4107QHF type ii secretion system protein e H5C80_05720 ENOG4105GVR general secretion pathway protein D H5C80_05725 ENOG4107KSE General secretion pathway protein C H5C80_05730 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression H5C80_05735 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication H5C80_05755 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) H5C80_05800 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) H5C80_05845 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) H5C80_05850 ENOG41067V7 50S ribosomal protein L36 H5C80_05880 ENOG4105VTS DnaJ-like, subfamily C H5C80_05885 ENOG4105W1Y Transcriptional regulator H5C80_05890 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system H5C80_05900 ENOG4105C1A potassium transporter peripheral membrane H5C80_05920 ENOG4105C79 DNA protecting protein DprA H5C80_05930 ENOG4108WI1 Dna topoisomerase H5C80_05945 ENOG4105SG3 Protein of unknown function (DUF1488) H5C80_05950 ENOG4108Z0R Transferase H5C80_05990 ENOG4105CDA abc transporter atp-binding protein H5C80_05995 ENOG4105DRP amino acid AbC transporter H5C80_06000 ENOG4105EZ7 amino acid ABC transporter H5C80_06010 ENOG4105XCM membrane LIPOPROTEIN H5C80_06015 ENOG4105BZS acriflavin resistance protein H5C80_06020 ENOG4105C1P efflux transporter, rnd family, mfp subunit H5C80_06025 ENOG4108XG4 DNA-binding transcriptional regulator H5C80_06030 ENOG41061ME transport protein H5C80_06035 ENOG4105CEC DNA methylase N-4 N-6 H5C80_06045 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) H5C80_06055 ENOG4108IA2 Sodium pantothenate symporter H5C80_06060 ENOG4105RG0 Membrane H5C80_06065 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase H5C80_06070 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein H5C80_06085 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family H5C80_06090 ENOG41062P1 Diguanylate cyclase phosphodiesterase H5C80_06100 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) H5C80_06105 ENOG4105VQ7 Rod shape-determining protein MreD H5C80_06115 ENOG4105C03 ribonuclease H5C80_06120 ENOG4105QD6 exported protein H5C80_06125 ENOG4105D1U peptidase U62 modulator of DNA gyrase H5C80_06130 ENOG4105CR8 Transcriptional regulator H5C80_06135 ENOG4105ZQC membrane protein AaeX H5C80_06150 ENOG4105UNR (Barnase) inhibitor H5C80_06155 ENOG4105RID UPF0379 protein yhcN H5C80_06170 ENOG4105C0H protease H5C80_06175 ENOG4105C0H protease H5C80_06180 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III H5C80_06185 ENOG4105D6Z AFG1 family ATPase H5C80_06200 ENOG4107MKT Stringent starvation protein a H5C80_06205 ENOG4105KB2 stringent starvation protein b H5C80_06210 ENOG4105CEE C4-dicarboxylate transporter H5C80_06240 ENOG4108R66 Conserved Protein H5C80_06245 ENOG4105DFS Conserved Protein H5C80_06250 ENOG4105BZ8 glutamate synthase H5C80_06255 ENOG4105CBC glutamate synthase H5C80_06260 ENOG4105N5T Radical SAM Protein H5C80_06265 ENOG4105BZU Histidine kinase H5C80_06270 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain H5C80_06280 ENOG4108NIH transferase activity, transferring phosphorus-containing groups H5C80_06285 ENOG41080Z8 PHOSPHOCARRIER protein H5C80_06295 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN H5C80_06300 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA H5C80_06305 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) H5C80_06310 ENOG4108IUZ ABC transporter H5C80_06315 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA H5C80_06320 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) H5C80_06330 ENOG4105C2X Arabinose 5-phosphate isomerase H5C80_06335 ENOG4105FEU K -dependent Na -Ca exchanger H5C80_06340 ENOG4105DHJ ABC, transporter H5C80_06345 ENOG4105CY3 ABC transporter, permease H5C80_06350 ENOG4107PE3 Mammalian cell entry related domain protein H5C80_06355 ENOG4105E3I toluene tolerance H5C80_06360 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane H5C80_06365 ENOG4105VFK BolA family H5C80_06375 ENOG4105HVQ Regulatory factor of maltose metabolism H5C80_06380 ENOG4105EAH synthase H5C80_06395 ENOG4105QYV Membrane H5C80_06405 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase H5C80_06410 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) H5C80_06415 ENOG4105HBR Rna-binding protein H5C80_06425 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) H5C80_06430 ENOG4105EEI dihydropteroate synthase H5C80_06440 ENOG4105NTZ Preprotein translocase subunit SecG H5C80_06450 ENOG4105DIJ Phosphoethanolamine transferase H5C80_06470 ENOG4105CHV Transcription elongation factor NusA H5C80_06510 ENOG4105C1J atp-dependent rna helicase H5C80_06515 ENOG4105CIC tryptophan-specific transport protein H5C80_06520 ENOG4105DEN Luciferase family H5C80_06540 ENOG4108YYD acetyltransferase H5C80_06555 ENOG4107R7Y intracellular protease Pfpi family H5C80_06560 ENOG4105K4T epimerase H5C80_06565 ENOG4107S21 permease H5C80_06570 ENOG4105W4M Transport-associated protein H5C80_06590 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) H5C80_06595 ENOG4106HBN Galactosamine-6-phosphate isomerase H5C80_06600 ENOG4105F3R pts system mannose fructose sorbose family iid H5C80_06605 ENOG4105ETZ PTS System H5C80_06610 ENOG4108UZY PTS System H5C80_06620 ENOG4105E70 isomerase H5C80_06625 ENOG4105CE4 GlcNAc 6-P deacetylase H5C80_06630 ENOG4108YTN IIa component H5C80_06635 ENOG4105F3R pts system mannose fructose sorbose family iid H5C80_06645 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB H5C80_06655 ENOG4105E98 transcriptional regulator DeoR family H5C80_06660 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression H5C80_06665 ENOG4105ZEG Suppressor protein H5C80_06670 ENOG4105CTX dehydratase H5C80_06675 ENOG4105DJB Major Facilitator Superfamily H5C80_06685 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase H5C80_06690 ENOG4105BZW Glycerate kinase H5C80_06705 ENOG410811B TRANSCRIPTIONal H5C80_06710 ENOG4105C7B Threonine dehydratase H5C80_06715 ENOG4108MST Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity) H5C80_06725 ENOG4105C6N Formate acetyltransferase H5C80_06730 ENOG4105KME endoribonuclease L-psp H5C80_06735 ENOG4105EJQ L-serine dehydratase H5C80_06740 ENOG4105C44 Serine transporter H5C80_06750 ENOG4106D80 Uncharacterized protein YhaL H5C80_06755 ENOG4108CNN domain protein H5C80_06760 ENOG4105CWB LysR family transcriptional Regulator H5C80_06765 ENOG4105KAF membrAne H5C80_06770 ENOG4105KAF membrAne H5C80_06775 ENOG4105CHF Glutathione S-transferase H5C80_06780 ENOG4108VBZ doxx family H5C80_06785 ENOG4105YJD H5C80_06790 ENOG41090KG Inner membrane protein YqjE H5C80_06795 ENOG4105NE1 Conserved Protein H5C80_06800 ENOG4105WAY exported protein H5C80_06805 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) H5C80_06810 ENOG4106W5V Membrane H5C80_06815 ENOG4107YCY Transcriptional regulator H5C80_06820 ENOG4105DPW Major facilitator superfamily MFS_1 H5C80_06830 ENOG4105CTX dehydratase H5C80_06835 ENOG4105P66 Membrane H5C80_06840 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) H5C80_06845 ENOG4105DU1 integral membrane protein, terc H5C80_06850 ENOG4105EE0 oxidoreductase H5C80_06855 ENOG4108UB4 uncharacterized protein ygjQ H5C80_06860 ENOG4108VKG metal-dependent hydrolase H5C80_06875 ENOG4108Z3N Transcriptional regulator H5C80_06880 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase H5C80_06885 ENOG4107WCA isomerase H5C80_06890 ENOG4107W6W Conserved Protein H5C80_06895 ENOG4105E5D amino acid H5C80_06900 ENOG4105FK9 beta-D-galactosidase beta subunit H5C80_06905 ENOG4105CNT hydrolase family 2 H5C80_06910 ENOG4105CQ4 Transcriptional regulator H5C80_06915 ENOG4108Y51 tRNA-binding protein H5C80_06925 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor H5C80_06930 ENOG4105NTW Transcriptional regulator H5C80_06935 ENOG4105Q26 Siderophore-interacting protein H5C80_06955 ENOG410679B prophage CP4-57 regulatory protein alpA H5C80_07030 ENOG4105CAR Terminase, large subunit H5C80_07050 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) H5C80_07055 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) H5C80_07070 ENOG4107QPK )-transporter H5C80_07075 ENOG4107GFK fumarate H5C80_07080 ENOG4106DSS Tartrate dehydratase subunit alpha H5C80_07095 ENOG4107ZVW dihydroneopterin aldolase H5C80_07110 ENOG4106MWK domain protein H5C80_07115 ENOG4105I7R Adenylate cyclase H5C80_07135 ENOG4107S78 Band 7 protein H5C80_07140 ENOG4105PV3 Inner membrane protein yqiJ H5C80_07150 ENOG4105W0Z cytoplasmic protein H5C80_07170 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b H5C80_07180 ENOG4108N92 Thiol disulfide Interchange Protein H5C80_07185 ENOG4108MR7 Arylsulfotransferase H5C80_07190 ENOG4106032 Glutathionylspermidine synthase H5C80_07200 ENOG4105DFG type I secretion outer membrane protein H5C80_07205 ENOG41087AY ADP-Ribose pyrophosphatase H5C80_07210 ENOG4108SX3 cytoplasmic protein H5C80_07215 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) H5C80_07220 ENOG4105IPS esterase H5C80_07225 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) H5C80_07245 ENOG4108RVA ribokinase H5C80_07265 ENOG4105CT4 transporter H5C80_07275 ENOG4105E0A ABC, transporter H5C80_07280 ENOG4105DQ5 transport system permease protein H5C80_07285 ENOG4105EHG Permease protein H5C80_07295 ENOG4106KNT transcriptional regulator H5C80_07300 ENOG4105VRH Antibiotic biosynthesis monooxygenase H5C80_07305 ENOG4105NF4 modulator of drug activity H5C80_07310 ENOG4105DHQ Histidine kinase H5C80_07315 ENOG4105XJC Two component transcriptional regulator (Winged helix family H5C80_07320 ENOG4105H4F exported protein H5C80_07325 ENOG4105F4I Transcriptional regulator H5C80_07330 ENOG4108J59 Extracellular solute-binding protein, family 5 H5C80_07335 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) H5C80_07340 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase H5C80_07345 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) H5C80_07350 ENOG4105CCT upf0313 protein H5C80_07360 ENOG4105ZKC Conserved Protein H5C80_07365 ENOG4105CV8 reductase H5C80_07370 ENOG4108I6A alcohol dehydrogenase H5C80_07375 ENOG4105CF7 AraC family transcriptional regulator H5C80_07380 ENOG4108K81 inner membrane protein YghB H5C80_07385 ENOG4105C28 cystathionine H5C80_07390 ENOG4105CWK Biopolymer transport protein, ExbB H5C80_07395 ENOG4108ZZF transport protein (ExbD) H5C80_07400 ENOG4105CYX Short-chain dehydrogenase reductase Sdr H5C80_07410 ENOG4105CPC Aldo Keto reductase H5C80_07420 ENOG410900S Protein of unknown function (DUF2623) H5C80_07425 ENOG4105E3S small subunit H5C80_07430 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein H5C80_07435 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit H5C80_07440 ENOG4105DPX Hydrogenase, large subunit H5C80_07445 ENOG4108USZ hydrogenase H5C80_07450 ENOG4108WGS hydrogenase 2-specific chaperone H5C80_07455 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) H5C80_07460 ENOG41082MF Hydrogenase assembly chaperone hypC hupF H5C80_07465 ENOG4105CYM Glutathione S-transferase H5C80_07470 ENOG4106032 Glutathionylspermidine synthase H5C80_07475 ENOG4105CJ3 phosphate transporter H5C80_07480 ENOG4108GH0 ATP-binding protein yghT H5C80_07485 ENOG4108NDC ATP-binding protein yghS H5C80_07490 ENOG4106FPV ATP-binding protein YghR H5C80_07495 ENOG4108S55 polysaccharide biosynthesis protein H5C80_07505 ENOG4108UUE Transcriptional regulator H5C80_07510 ENOG4108M8S permease YjgP YjgQ family protein H5C80_07520 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) H5C80_07525 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) H5C80_07545 ENOG4108KWP DNA-binding transcriptional regulator GlcC H5C80_07550 ENOG4105CQB FAD linked oxidase domain protein H5C80_07555 ENOG4105EU8 FAD linked oxidase domain protein H5C80_07560 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) H5C80_07565 ENOG4108ZJF Glcg protein H5C80_07570 ENOG4107QP3 malate synthase g H5C80_07575 ENOG4105DAA L-lactate H5C80_07580 ENOG4105F88 accessory colonization factor AcfD H5C80_07585 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) H5C80_07590 ENOG410765S (LipO)protein H5C80_07605 ENOG4107QHF type ii secretion system protein e H5C80_07610 ENOG4105D7Q type ii secretion system H5C80_07615 ENOG4108VAU general secretion pathway protein G H5C80_07625 ENOG4105X5Z General secretion pathway protein I H5C80_07645 ENOG4105U1E general secretion pathway protein M H5C80_07670 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles H5C80_07680 ENOG4108YGG dna repair protein H5C80_07685 ENOG4105MFG Antirestriction protein H5C80_07690 ENOG4106H6R UPF0380 protein H5C80_07705 ENOG4108KZE transcriptional regulator H5C80_07710 ENOG4105TS0 gtp-binding protein H5C80_07750 ENOG4108F5E vimentin H5C80_07770 ENOG4105T40 surface antigen msp4 family protein H5C80_07775 ENOG4108I6E Sulfatase H5C80_07790 ENOG4105X54 addiction module antidote protein H5C80_07815 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles H5C80_07825 ENOG4108YGG dna repair protein H5C80_07830 ENOG4106549 Antirestriction protein H5C80_07835 ENOG4106H6R UPF0380 protein H5C80_07850 ENOG4108KZE transcriptional regulator H5C80_07855 ENOG4105TS0 gtp-binding protein H5C80_07925 ENOG4108R0M Aminoglycoside H5C80_08000 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) H5C80_08050 ENOG4105WBN Transcriptional regulator (LacI family H5C80_08060 ENOG4105T40 surface antigen msp4 family protein H5C80_08085 ENOG4105DIJ Phosphoethanolamine transferase H5C80_08115 ENOG4105CDU Replicative dna helicase H5C80_08205 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) H5C80_08225 ENOG4108UUM single-stranded DNA-binding protein H5C80_08345 ENOG4105D05 Receptor H5C80_08515 ENOG4107QHF type ii secretion system protein e H5C80_08570 ENOG4108UQV Membrane H5C80_08575 ENOG4105CXN decarboxylase H5C80_08580 ENOG4105EAA nucleoside H5C80_08595 ENOG4105CEN a g-specific adenine glycosylase H5C80_08605 ENOG41090ED Protein with unknown function (DUF469) H5C80_08610 ENOG4105K33 Periplasmic Protein H5C80_08615 ENOG4105HDK L-asparaginase H5C80_08620 ENOG4106MH3 alpha helix chain H5C80_08625 ENOG4105CG6 trap dicarboxylate transporter dctm subunit H5C80_08630 ENOG41069H7 transport system small permease component H5C80_08635 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit H5C80_08640 ENOG4105CSA Coproporphyrinogen iii oxidase H5C80_08645 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) H5C80_08655 ENOG4108VIA integral membrane protein H5C80_08660 ENOG4105DFA alanine racemase domain protein H5C80_08665 ENOG4105CZX twitching motility protein H5C80_08680 ENOG4105D7Z glutathione synthase H5C80_08685 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) H5C80_08690 ENOG4105RWS endonuclease I H5C80_08700 ENOG4107QNK )-transporter H5C80_08720 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) H5C80_08735 ENOG4108K0D peptidase, M48 H5C80_08740 ENOG4105CV1 Transketolase (EC 2.2.1.1) H5C80_08745 ENOG4105EPW hflc protein H5C80_08750 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia H5C80_08755 ENOG4105CTS PTS system mannitol-specific H5C80_08760 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein H5C80_08765 ENOG4108Q8A Fructose-1,6-bisphosphatase H5C80_08770 ENOG4108R4K DNA-binding, transcriptional regulator H5C80_08775 ENOG4107Z1W Fructose transport system kinase H5C80_08790 ENOG4105D2N Aldolase H5C80_08795 ENOG4105D64 Mechanosensitive ion channel H5C80_08800 ENOG4108ZUB Lysine exporter protein (Lyse ygga) H5C80_08805 ENOG4105MPN Membrane H5C80_08810 ENOG4105DEQ transcriptional regulator H5C80_08815 ENOG4105CYC Transferase H5C80_08820 ENOG4108M7F enoyl-CoA hydratase isomerase H5C80_08825 ENOG4105DJT lAO AO transport system ATPase H5C80_08830 ENOG4105D5P Methylmalonyl-coA mutase H5C80_08850 ENOG4108JQ1 Dehydrogenase H5C80_08860 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase H5C80_08880 ENOG4107RAQ aminopeptidase H5C80_08885 ENOG4105D0A hydroxylase H5C80_08890 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family H5C80_08915 ENOG4105CS2 ec 3.2.1.21 H5C80_08920 ENOG4105N5Z UPF0267 protein H5C80_08925 ENOG4108UT2 hemolysin iii H5C80_08935 ENOG4105Y75 tpr repeat protein H5C80_08940 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB H5C80_08945 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) H5C80_08950 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) H5C80_08955 ENOG4105T95 Thiol disulfide interChange protein H5C80_08960 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) H5C80_08970 ENOG4105CRK lysyL-tRNA synthetase H5C80_08975 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) H5C80_08985 ENOG4105C2W permease H5C80_08990 ENOG4105BZ8 glutamate synthase H5C80_08995 ENOG4108R8B oxidoreductase Fe-S subunit H5C80_09000 ENOG4105C7N Xanthine uracil vitamin C permease H5C80_09005 ENOG4107QUY Guanine deaminase H5C80_09010 ENOG4105C2W permease H5C80_09015 ENOG4105C7W Xanthine dehydrogenase H5C80_09020 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase H5C80_09025 ENOG4107UUR Chlorohydrolase aminohydrolase H5C80_09030 ENOG4105BZ8 glutamate synthase H5C80_09035 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase H5C80_09040 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC H5C80_09045 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family H5C80_09050 ENOG4105C5B carbamate kinase H5C80_09060 ENOG4107S4Y M20 DapE family protein YgeY H5C80_09065 ENOG4107RCH Diaminopropionate ammonia-lyase H5C80_09070 ENOG4105IW6 Carbamoyltransferase H5C80_09075 ENOG4108JUB Transcriptional regulator H5C80_09080 ENOG4108UTP (2Fe-2S)-binding domain protein H5C80_09085 ENOG4108HR6 Dehydrogenase H5C80_09090 ENOG4105C7W Xanthine dehydrogenase H5C80_09095 ENOG4108K5P (LipO)protein H5C80_09105 ENOG4108MHD transport protein H5C80_09110 ENOG4105CHU acetyl-coa acetyltransferase H5C80_09120 ENOG4105CHR reductase H5C80_09125 ENOG4107QNK )-transporter H5C80_09135 ENOG4105RQF LysR family Transcriptional regulator H5C80_09145 ENOG41060NJ transcriptional regulator H5C80_09160 ENOG4105CPC Aldo Keto reductase H5C80_09165 ENOG4105SUV lipoprotein YgdR H5C80_09170 ENOG4105EE5 Membrane protein terC H5C80_09185 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase H5C80_09200 ENOG4105IPU prepilin peptidase dependent protein A H5C80_09205 ENOG4105JCS prepilin peptidase dependent protein H5C80_09210 ENOG4105SEN Protein of unknown function (DUF2509) H5C80_09215 ENOG4105RVB Prepilin peptidase dependent protein c H5C80_09220 ENOG4105DSY exodeoxyribonuclease V, gamma H5C80_09225 ENOG4107QXK peptidase H5C80_09230 ENOG4107QKA exodeoxyribonuclease V beta H5C80_09235 ENOG4107QYX exodeoxyribonuclease v alpha H5C80_09240 ENOG4108EKC n-acetylglutamate synthase H5C80_09245 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase H5C80_09255 ENOG4105CI1 PTS System H5C80_09260 ENOG4105C87 Aminotransferase class I and II H5C80_09265 ENOG4105C2X Arabinose 5-phosphate isomerase H5C80_09350 ENOG4108ZG0 Ompa motb domain protein H5C80_09385 ENOG4105CA3 membrane-bound lytic murein transglycosylase H5C80_09395 ENOG4105CUZ uba thif-type nad fad binding protein H5C80_09400 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) H5C80_09405 ENOG4105C9B Cysteine desulfurase H5C80_09410 ENOG4105M5B (LipO)protein H5C80_09415 ENOG4105ETT transcriptional Regulator, LysR family H5C80_09420 ENOG4105M08 Membrane H5C80_09430 ENOG4107EDW L-fucose operon activator H5C80_09440 ENOG4105CMG Carbohydrate kinase H5C80_09445 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) H5C80_09450 ENOG4105EDR glucose galactose transporter H5C80_09455 ENOG4107W7X Aldolase H5C80_09460 ENOG4105C0A alcohol dehydrogenase H5C80_09470 ENOG4105EJQ L-serine dehydratase H5C80_09475 ENOG4105C44 Serine transporter H5C80_09480 ENOG4105EWT decarboxylase family H5C80_09495 ENOG4105WP7 tRNA pseudouridine synthase C H5C80_09500 ENOG4105DR9 pseudouridine synthase H5C80_09505 ENOG4105QDK Flavodoxin H5C80_09510 ENOG4105DJB Major Facilitator Superfamily H5C80_09515 ENOG4105EQX glucarate dehydratase H5C80_09520 ENOG4105EQX glucarate dehydratase H5C80_09525 ENOG4105BZU Histidine kinase H5C80_09535 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) H5C80_09540 ENOG4105DXN mazG family H5C80_09560 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) H5C80_09565 ENOG4108CWB sugar kinase ygcE H5C80_09570 ENOG4108ITV Inner membrane protein yqcE H5C80_09575 ENOG4105CHR reductase H5C80_09580 ENOG4107R3A FAD linked oxidase domain protein H5C80_09585 ENOG4105C54 Major Facilitator superfamily H5C80_09590 ENOG4106IKH Electron transfer flavoprotein H5C80_09595 ENOG4105YBM electron transfer flavoprotein subunit ygcQ H5C80_09600 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator H5C80_09605 ENOG4105WQV ferredoxin-like protein H5C80_09610 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase H5C80_09615 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase H5C80_09630 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) H5C80_09635 ENOG4107635 Hok Gef family protein H5C80_09640 ENOG4108SER Transposase H5C80_09645 ENOG4105DTT CRISPR-associated helicase, cas3 H5C80_09650 ENOG4105CYR Crispr-associated protein, cse1 family H5C80_09660 ENOG41060M0 Crispr-associated protein, cse4 family H5C80_09665 ENOG4108VWQ crispr-associated protein H5C80_09675 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) H5C80_09680 ENOG4105PWE CRISPR-associated protein cas2 H5C80_09685 ENOG4108MXK alkaline phosphatase isozyme conversion H5C80_09705 ENOG4105N0Z inner membrane protein ygbE H5C80_09725 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) H5C80_09740 ENOG4108K5P (LipO)protein H5C80_09745 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) H5C80_09755 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase H5C80_09760 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) H5C80_09765 ENOG4105KZM cytoplasmic protein H5C80_09770 ENOG4105C6Z Gluconate H5C80_09775 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) H5C80_09780 ENOG4105FB2 class II Aldolase H5C80_09785 ENOG4105G63 Type III effector Hrp-dependent H5C80_09795 ENOG4105MVE transcriptional regulator H5C80_09800 ENOG4105MEW serine threonine protein phosphatase H5C80_09815 ENOG4105VXR cytoplasmic protein H5C80_09825 ENOG4108JUA Transcriptional regulator H5C80_09830 ENOG4105C45 hydrogenase expression formation protein (HypE) H5C80_09835 ENOG4105CQS hydrogenase expression formation protein HypD H5C80_09840 ENOG41083WG hydrogenase assembly chaperone H5C80_09845 ENOG4107RSS Hydrogenase accessory protein HypB H5C80_09850 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) H5C80_09855 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA H5C80_09860 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) H5C80_09865 ENOG4107R30 NADH dehydrogenase H5C80_09870 ENOG4107TDF Formate hydrogenlyase subunit 4 H5C80_09875 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) H5C80_09880 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit H5C80_09885 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit H5C80_09890 ENOG4105I6X formate hydrogenlyase maturation H5C80_09895 ENOG4108MG9 hydrogenase 3 maturation protease H5C80_09900 ENOG4105CS2 ec 3.2.1.21 H5C80_09905 ENOG4105C5Y PTS System H5C80_09910 ENOG4105DDV Transcriptional regulator (LacI family H5C80_09915 ENOG4108RC0 Electron transport protein H5C80_09920 ENOG4105C8H hydrogenase maturation protein Hypf H5C80_09935 ENOG4108JUA Transcriptional regulator H5C80_09940 ENOG4105C2X Arabinose 5-phosphate isomerase H5C80_09945 ENOG410804X Transcriptional regulator H5C80_09950 ENOG4105J92 DNA-binding transcriptional activator GutM H5C80_09955 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase H5C80_09960 ENOG4105VI0 Pts system, glucitol sorbitol-specific H5C80_09965 ENOG4105DZY Pts system, glucitol sorbitol-specific H5C80_09970 ENOG410787A Pts system, glucitol sorbitol-specific H5C80_09975 ENOG4105CVE Lytic murein transglycosylase H5C80_09980 ENOG4107TH8 cina domain protein H5C80_10000 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) H5C80_10030 ENOG4107VXZ Hydrolase H5C80_10035 ENOG4105W39 Membrane H5C80_10050 ENOG4105C0R drug resistance transporter emrb qaca subfamily H5C80_10055 ENOG4105CW7 secretion protein, HlyD family H5C80_10060 ENOG4105NTK Transcriptional repressor Mpra H5C80_10065 ENOG4105ZED uncharacterized protein ygaH H5C80_10070 ENOG4108UMN azlc family H5C80_10080 ENOG4105GIJ Glycine betaine H5C80_10085 ENOG4108HQS Glycine betaine H5C80_10090 ENOG4108IJ7 Glycine betaine H5C80_10095 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) H5C80_10100 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) H5C80_10110 ENOG4105WAZ (Glutaredoxin-like protein) NrdH H5C80_10115 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) H5C80_10120 ENOG4108WMJ Protein of unknown function (DUF2002) H5C80_10125 ENOG4108RNS Exports L-alanine (By similarity) H5C80_10130 ENOG4108X73 DNA- binding protein H5C80_10135 ENOG4108V62 Rhodanese domain protein H5C80_10140 ENOG41080HT Transcriptional regulator, arsr family H5C80_10145 ENOG4105VPI YqaE family transport protein H5C80_10150 ENOG4109066 lysm domain bon superfamily protein H5C80_10155 ENOG4108PVQ transcriptional regulator H5C80_10160 ENOG4105C85 amino acid H5C80_10165 ENOG4108JPW Aminotransferase H5C80_10170 ENOG4105C26 Dehydrogenase H5C80_10175 ENOG4105D5U fad dependent oxidoreductase H5C80_10195 ENOG4108Z1B Cyclase dehydrase H5C80_10205 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) H5C80_10210 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) H5C80_10225 ENOG4108JU6 CBS domain protein H5C80_10230 ENOG4106KVJ cytochrome C assembly protein H5C80_10235 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY H5C80_10260 ENOG41090EK ompa motb domain protein H5C80_10265 ENOG4108KHX Diguanylate cyclase H5C80_10270 ENOG4108WS1 H5C80_10275 ENOG4105QP9 Protein of unknown function (DUF2799) H5C80_10280 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) H5C80_10285 ENOG4105EHE chorismate mutase- prephenate dehydrogenase H5C80_10290 ENOG4105CQC Prephenate dehydratase H5C80_10300 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA H5C80_10310 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane H5C80_10315 ENOG4105C34 Pseudouridine synthase H5C80_10320 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase H5C80_10325 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit H5C80_10350 ENOG4105CSH Transporter H5C80_10355 ENOG4105T42 (LipO)protein H5C80_10360 ENOG4105JIM Phosphatidylserine synthase H5C80_10365 ENOG4105CD5 CoA-binding domain protein H5C80_10370 ENOG4106IUH DTW domain containing protein H5C80_10375 ENOG4105K63 Thioredoxin H5C80_10380 ENOG4105EIB trna rrna methyltransferase H5C80_10400 ENOG41090KR LysR family transcriptional Regulator H5C80_10405 ENOG4105C1J atp-dependent rna helicase H5C80_10415 ENOG4108IYU L-aspartate oxidase H5C80_10425 ENOG4105EMN RNA polymerase sigma factor H5C80_10430 ENOG41069PW sigma-e factor negative regulatory protein H5C80_10435 ENOG4105VQK sigma E regulatory protein, MucB RseB H5C80_10440 ENOG4105WMJ Positive regulator of sigma E, RseC MucC H5C80_10450 ENOG4105C3F Signal peptidase i H5C80_10470 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) H5C80_10485 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding H5C80_10490 ENOG4106G6Q Transcriptional regulator H5C80_10495 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB H5C80_10500 ENOG4108Z6B deaminase H5C80_10510 ENOG4108ETH Formylglycinamide ribotide synthetase H5C80_10515 ENOG4107WP9 Histidine kinase H5C80_10520 ENOG4108SKK alpha helix protein H5C80_10525 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family H5C80_10535 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) H5C80_10545 ENOG4108NZE NAGC-like transcriptional regulator H5C80_10550 ENOG4107HQ7 repeat protein H5C80_10555 ENOG4105FCA ABC transporter periplasmic-binding protein YphF H5C80_10560 ENOG4108F37 ATP-binding component of a transport system H5C80_10565 ENOG4105CNN ABC, transporter H5C80_10570 ENOG4105CPQ Dehydrogenase H5C80_10575 ENOG4108ZKT aldose 1-epimerase H5C80_10580 ENOG4108SB3 DoxX Family H5C80_10605 ENOG4105FUY alpha subunit H5C80_10610 ENOG4108W5M transcriptional regulator H5C80_10615 ENOG4105D8G Major Facilitator superfamily H5C80_10620 ENOG4108MN2 Stationary phase inducible protein CsiE H5C80_10625 ENOG4107XM9 (LipO)protein H5C80_10630 ENOG4105ECY inositol monophosphatase H5C80_10650 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins H5C80_10670 ENOG4108ZIT Ferredoxin, 2FE-2S H5C80_10675 ENOG4105WVQ Fe-S assembly protein IscX H5C80_10685 ENOG4105YYA enhanced serine sensitivity protein SseB H5C80_10690 ENOG4105KHC sulfurtransferase H5C80_10695 ENOG4105DN3 alpha-2-macroglobulin domain protein H5C80_10700 ENOG4108JQB penicillin-binding protein 1C H5C80_10730 ENOG4105N21 Membrane H5C80_10745 ENOG4105VPD cellular component movement H5C80_10770 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) H5C80_10780 ENOG41066DY Membrane H5C80_10785 ENOG4108ZMA Outer membrane lipoprotein H5C80_10790 ENOG41062G3 Protein of unknown function (DUF2633) H5C80_10800 ENOG4105BZU Histidine kinase H5C80_10805 ENOG4105C9X ppx gppa phosphatase H5C80_10810 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) H5C80_10815 ENOG4108V3E phosphoribosylglycinamide formyltransferase H5C80_10830 ENOG4105C2W permease H5C80_10835 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) H5C80_10840 ENOG4105K89 arsenate reductase H5C80_10845 ENOG4105ERG peptidase m48, ste24p H5C80_10850 ENOG4105C02 permease H5C80_10855 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen H5C80_10860 ENOG4105RH4 Glycine cleavage system transcriptional repressor H5C80_10870 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) H5C80_10885 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A H5C80_10890 ENOG4105CGZ zinc metallopeptidase H5C80_10900 ENOG4106KED esterase YpfH H5C80_10915 ENOG4105KUZ arsenate reductase H5C80_10925 ENOG4105BZS acriflavin resistance protein H5C80_10930 ENOG4105BZU Histidine kinase H5C80_10935 ENOG4105BZ8 glutamate synthase H5C80_10945 ENOG4108PVD exported protein H5C80_10950 ENOG4105CV1 Transketolase (EC 2.2.1.1) H5C80_10955 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) H5C80_10960 ENOG4105C6K Malic enzyme H5C80_10965 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place H5C80_10970 ENOG4106S4J ethanolamine utilization protein EutP H5C80_10975 ENOG4105NDK ethanolamine utilization protein H5C80_10980 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase H5C80_10985 ENOG4107WUY phosphate acetyltransferase H5C80_10990 ENOG4105KNY Microcompartments protein H5C80_10995 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml H5C80_11000 ENOG4108EKI Dehydrogenase H5C80_11005 ENOG4107RWI ethanolamine utilization protein eutJ H5C80_11010 ENOG4105C0A alcohol dehydrogenase H5C80_11015 ENOG4105ENY Ethanolamine utilization protein eutH H5C80_11020 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase H5C80_11025 ENOG4105CPD ethanolamine ammonia-lyase H5C80_11035 ENOG4106D67 ethanolamine utilization protein H5C80_11040 ENOG4108X49 Ethanolamine utilization protein EutK H5C80_11045 ENOG4108K3Z AraC family transcriptional regulator H5C80_11055 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase H5C80_11065 ENOG4105QZU Inner membrane protein YfeZ H5C80_11070 ENOG4105E7K (LipO)protein H5C80_11075 ENOG4105EZR dyp-type peroxidase family protein H5C80_11080 ENOG4107S1E Beta-lactamase H5C80_11085 ENOG4105C5Y PTS System H5C80_11100 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr H5C80_11105 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein H5C80_11110 ENOG4108I5D sulfate abc transporter H5C80_11115 ENOG4105ECW sulfate abc transporter H5C80_11120 ENOG4108IJ6 ABC transporter H5C80_11125 ENOG4105C6T cysteine synthase H5C80_11130 ENOG4105M0Y H5C80_11140 ENOG4105C5Y PTS System H5C80_11145 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) H5C80_11155 ENOG4105C6T cysteine synthase H5C80_11175 ENOG4105VRT cytoplasmic protein H5C80_11180 ENOG4105DHU Bile acid H5C80_11185 ENOG4108M0I Transcriptional regulator H5C80_11190 ENOG4108NFH Sugar hydrolase H5C80_11195 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) H5C80_11200 ENOG4105EAA nucleoside H5C80_11210 ENOG4105CN8 Transcriptional regulator H5C80_11240 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) H5C80_11245 ENOG4105GXM Putative transcription regulator (DUF1323) H5C80_11250 ENOG4105HZG regulatoR H5C80_11265 ENOG4108KMM Diguanylate cyclase H5C80_11270 ENOG4105D9N nucleoside H5C80_11280 ENOG4109076 Conserved Protein H5C80_11295 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) H5C80_11300 ENOG410863U PTS System H5C80_11305 ENOG4105DC7 peptidase M24 H5C80_11310 ENOG4105CN9 Peptidase m42 family protein H5C80_11315 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) H5C80_11320 ENOG4108CIP transcriptional regulator H5C80_11325 ENOG4105DY9 regulatoR H5C80_11330 ENOG4108HRK Histidine kinase H5C80_11335 ENOG4105CHM Aminotransferase H5C80_11345 ENOG4105D1S lipid A biosynthesis H5C80_11350 ENOG4105W9M Membrane H5C80_11360 ENOG4108V08 YfdX protein H5C80_11370 ENOG4105CFN oxalyl-CoA decarboxylase H5C80_11375 ENOG4108N2Y auxin Efflux H5C80_11380 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F H5C80_11390 ENOG4108WQH regulatoR H5C80_11395 ENOG4105CW7 secretion protein, HlyD family H5C80_11400 ENOG4105C0R drug resistance transporter emrb qaca subfamily H5C80_11415 ENOG4106NDP Transcriptional regulator H5C80_11420 ENOG4108HKT sucrose-6-phosphate hydrolase H5C80_11425 ENOG4105D7K pfkb domain protein H5C80_11430 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) H5C80_11445 ENOG4105S64 Formate nitrite transporter H5C80_11450 ENOG410903C (LipO)protein H5C80_11455 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation H5C80_11460 ENOG4105KZW UPF0381 protein H5C80_11475 ENOG4108BY2 phosphohistidine phosphatase H5C80_11485 ENOG4106PG1 outer membrane usher protein H5C80_11490 ENOG4108FZ9 Chaperone H5C80_11495 ENOG4105NEV Fimbrial H5C80_11500 ENOG4105UGQ Fimbrial H5C80_11505 ENOG4105US4 fimbrial-like protein yfcP H5C80_11525 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase H5C80_11530 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) H5C80_11535 ENOG4105EJ9 Membrane H5C80_11540 ENOG4108BPE -transporting atpase H5C80_11545 ENOG4105MH2 YfcL protein H5C80_11555 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) H5C80_11560 ENOG4105F9N Major Facilitator Superfamily H5C80_11565 ENOG4106WZ1 flagella biosynthesis regulator H5C80_11575 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) H5C80_11585 ENOG4105DQR SNARE associated Golgi H5C80_11595 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase H5C80_11600 ENOG4108S3P Sporulation domain protein H5C80_11605 ENOG4105E96 Colicin v production protein H5C80_11610 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase H5C80_11615 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase H5C80_11620 ENOG4105E89 ABC transporter H5C80_11625 ENOG4105E89 ABC transporter H5C80_11630 ENOG4105DSP amino acid AbC transporter H5C80_11635 ENOG4106YG3 ABC transporter H5C80_11640 ENOG4108JEH abc transporter atp-binding protein H5C80_11645 ENOG4105DNE Transposase H5C80_11650 ENOG4105ECP epimerase H5C80_11655 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase H5C80_11660 ENOG4105CYM Glutathione S-transferase H5C80_11665 ENOG4108SHQ Glutathione S-transferase H5C80_11670 ENOG4108RE9 Phosphodiesterase H5C80_11675 ENOG4105PTV Nudix Hydrolase H5C80_11680 ENOG4105CSX c4-dicarboxylate anaerobic carrier H5C80_11685 ENOG4105C6K Malic enzyme H5C80_11690 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) H5C80_11700 ENOG4105XWI UPF0304 protein H5C80_11705 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 H5C80_11710 ENOG4107QWE )-transporter H5C80_11720 ENOG4105CHM Aminotransferase H5C80_11725 ENOG4107NQ8 LysR family Transcriptional regulator H5C80_11745 ENOG4105GKE subunit e H5C80_11750 ENOG4107QIZ NADH dehydrogenase H5C80_11755 ENOG4108IEH NADH dehydrogenase subunit g H5C80_11770 ENOG4107UFS subunit j H5C80_11780 ENOG4105D65 subunit l H5C80_11785 ENOG4105C8S subunit m H5C80_11795 ENOG4105GDX Domain of unknown function (DUF1877) H5C80_11800 ENOG4107VAM peptidase, m28 H5C80_11805 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is H5C80_11815 ENOG4107YB6 acetyltransferase, (GNAT) family H5C80_11820 ENOG4105TNS Conserved Protein H5C80_11825 ENOG4105E4F Isochorismate synthase H5C80_11840 ENOG4108IPT Naphthoate synthase H5C80_11845 ENOG4105DNI Converts SHCHC to OSB (By similarity) H5C80_11850 ENOG4105CEY Amp-dependent synthetase and ligase H5C80_11855 ENOG4106GZG polymyxin resistance protein B H5C80_11870 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) H5C80_11905 ENOG4108UII YfaZ family H5C80_11910 ENOG4108EWA cinA-like protein H5C80_11920 ENOG4105CSP Major Facilitator Superfamily H5C80_11935 ENOG4105DNE Transposase H5C80_11940 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) H5C80_11950 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A H5C80_11955 ENOG4105CXY transporter H5C80_11960 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase H5C80_11965 ENOG4105FQR PH-inducible protein involved in stress response H5C80_11970 ENOG4105XPH Ferredoxin H5C80_11975 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) H5C80_11980 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) H5C80_11985 ENOG4107GHC outer membrane autotransporter H5C80_11995 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) H5C80_12000 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) H5C80_12005 ENOG4108QJJ Protein of unknown function (DUF1175) H5C80_12010 ENOG4107S52 alpha-2-macroglobulin domain protein H5C80_12015 ENOG41081SK signal peptide protein H5C80_12020 ENOG4105EDV vault protein H5C80_12025 ENOG4105CHU acetyl-coa acetyltransferase H5C80_12030 ENOG4105CRW Short chain fatty acid transporter H5C80_12035 ENOG4107QNJ CoA-transferase subunit B H5C80_12040 ENOG4107QP7 CoA-transferase subunit A H5C80_12045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family H5C80_12050 ENOG4105BZU Histidine kinase H5C80_12055 ENOG4105BZU Histidine kinase H5C80_12060 ENOG41068CG regulatoR H5C80_12065 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC H5C80_12070 ENOG4105FCK Membrane H5C80_12075 ENOG4105CJ2 (LipO)protein H5C80_12080 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) H5C80_12085 ENOG4105CF1 Alkylated DNA repair protein H5C80_12090 ENOG4105IBP Cyclic peptide transporter H5C80_12105 ENOG4108ZNS ferredoxin-type protein NapF H5C80_12110 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase H5C80_12120 ENOG4108BGM Quinol dehydrogenase periplasmic component H5C80_12125 ENOG4105GXZ Ferredoxin-type protein NapH H5C80_12130 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) H5C80_12135 ENOG4105CUW cytochrome C-TYPE protein H5C80_12140 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) H5C80_12145 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) H5C80_12150 ENOG41060IM Heme exporter protein H5C80_12155 ENOG4105X3C heme exporter protein H5C80_12165 ENOG4105DA4 cytochrome c-type biogenesis protein H5C80_12170 ENOG4107QX9 Thiol disulfide interChange protein H5C80_12175 ENOG4105KWW Biogenesis protein H5C80_12180 ENOG4105WH1 Two component transcriptional regulator luxr family H5C80_12195 ENOG4105E68 Sulfatase H5C80_12215 ENOG4105CFI type iii restriction protein res subunit H5C80_12220 ENOG4105I08 Pseudouridine synthase H5C80_12225 ENOG4105C2C drug resistance transporter, Bcr CflA H5C80_12230 ENOG4105HG6 H5C80_12235 ENOG4108JQ5 ABC transporter H5C80_12240 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component H5C80_12245 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component H5C80_12250 ENOG4105E43 Extracellular solute-binding protein, family 5 H5C80_12255 ENOG4105CXC rtn protein H5C80_12260 ENOG4107TT5 NLP P60 protein H5C80_12265 ENOG41076MN Phosphoesterase, PA-phosphatase related H5C80_12270 ENOG4105CKI cobalamin synthesis protein H5C80_12275 ENOG4105DEI Mannitol dehydrogenase H5C80_12285 ENOG4105KRS Proteinase inhibitor H5C80_12290 ENOG4105S8Q sugar efflux transporter H5C80_12295 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein H5C80_12300 ENOG4105DE4 1-phosphofructokinase H5C80_12305 ENOG4105DM4 PTS System H5C80_12310 ENOG4105DD7 kinase (PfkB family H5C80_12315 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) H5C80_12320 ENOG4105D9N nucleoside H5C80_12325 ENOG4108Y4K DNA-binding transcriptional activator H5C80_12335 ENOG4105D9N nucleoside H5C80_12340 ENOG4105DD7 kinase (PfkB family H5C80_12350 ENOG4105HMI Membrane H5C80_12355 ENOG4105DUM transcriptional regulator, lysR family H5C80_12360 ENOG4108IQI permease H5C80_12370 ENOG4105C4W S-formylglutathione hydrolase H5C80_12380 ENOG4105DHF Membrane H5C80_12385 ENOG41060NJ transcriptional regulator H5C80_12390 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator H5C80_12395 ENOG4105C2J ABC transporter H5C80_12400 ENOG4108HWV )-transporter H5C80_12405 ENOG4107SJI Dehydrogenase H5C80_12410 ENOG4105BZ8 glutamate synthase H5C80_12415 ENOG4105Y9N Membrane H5C80_12420 ENOG4107GZ4 SanA protein H5C80_12430 ENOG41067MG lrgb family H5C80_12460 ENOG4108RXX maleylacetoacetate isomerase H5C80_12465 ENOG4105MSY salicylate hydroxylase H5C80_12470 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) H5C80_12480 ENOG4105ETP RND efflux system, outer membrane lipoprotein H5C80_12485 ENOG4105H9W Short-chain dehydrogenase reductase Sdr H5C80_12490 ENOG4105KHU inner membrane protein YohD H5C80_12495 ENOG41069YE inner membrane protein yohC H5C80_12500 ENOG41061WM D-Alanyl-D-Alanine H5C80_12505 ENOG4105CXG d-lactate dehydrogenase H5C80_12510 ENOG4107QK4 glycoside hydrolase, family 3 domain protein H5C80_12515 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system H5C80_12520 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component H5C80_12525 ENOG4108IJ8 ABC transporter H5C80_12530 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component H5C80_12540 ENOG4108XDN Transcriptional regulator H5C80_12545 ENOG4108HRK Histidine kinase H5C80_12550 ENOG4108NEV two component transcriptional regulator, LytTR family H5C80_12555 ENOG4108W15 Protein of unknown function (DUF1456) H5C80_12560 ENOG4108YCW (LipO)protein H5C80_12565 ENOG410903U zinc ion binding H5C80_12570 ENOG4105DEG Vwa containing coxe family protein H5C80_12575 ENOG4105RD5 H5C80_12580 ENOG4105KKX ATPase associated with various cellular activities aaa_5 H5C80_12590 ENOG4108KDT Molybdate metabolism regulator H5C80_12595 ENOG4108KDT Molybdate metabolism regulator H5C80_12605 ENOG4105D1F ATP-binding protein H5C80_12610 ENOG41067AK Protein of unknown function (DUF2574) H5C80_12615 ENOG41063W2 Fimbrial protein H5C80_12620 ENOG4108MQF Chaperone H5C80_12625 ENOG4105CW0 outer membrane usher protein H5C80_12630 ENOG410662B Type-1 fimbrial protein H5C80_12635 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly H5C80_12655 ENOG4105DWF phosphomethylpyrimidine kinase H5C80_12660 ENOG4108UQ1 hydrolase, family 25 H5C80_12665 ENOG4105FDP GntR family transcriptional regulator H5C80_12670 ENOG4108TFM Kinase, PfkB family H5C80_12675 ENOG4108KD5 ADP-ribosylation crystallin J1 H5C80_12680 ENOG4105EAA nucleoside H5C80_12685 ENOG4105EIE fructose-bisphosphate aldolase H5C80_12700 ENOG41082GB PTS system galactitol-specific transporter subunit IIA H5C80_12705 ENOG41090UW PTS System H5C80_12710 ENOG4105DT3 PTS system, galactitol-specific IIc component H5C80_12715 ENOG4107WTH Galactitol-1-phosphate dehydrogenase H5C80_12730 ENOG41076Z6 Uncharacterized protein yegR H5C80_12735 ENOG4105CFP Peptidase U32 H5C80_12740 ENOG4105KWI UPF0339 protein H5C80_12745 ENOG4105E3W Two component transcriptional regulator (Winged helix family H5C80_12750 ENOG4105EB3 Histidine kinase H5C80_12760 ENOG4105BZS acriflavin resistance protein H5C80_12765 ENOG4105BZS acriflavin resistance protein H5C80_12790 ENOG4108M24 von Willebrand factor, type A H5C80_12795 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase H5C80_12800 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding H5C80_12805 ENOG4105R8A Heat shock protein H5C80_12810 ENOG4105D03 DNA-3-methyladenine glycosylase II H5C80_12820 ENOG4105DBI uridine monophosphokinase H5C80_12830 ENOG4108GAE asmA family H5C80_12835 ENOG4105EE5 Membrane protein terC H5C80_12845 ENOG4105DAY polysaccharide export protein H5C80_12850 ENOG4105KJF protein tyrosine phosphatase H5C80_12855 ENOG4105D75 Capsular exopolysaccharide family H5C80_12860 ENOG41090RK glycosyl transferase H5C80_12865 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB H5C80_12870 ENOG4107RXY Glycosyl transferase H5C80_12875 ENOG4108NYJ Colanic acid H5C80_12880 ENOG4105ECJ Glycosyl Transferase H5C80_12885 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF H5C80_12890 ENOG4105C0K Gdp-mannose 4,6-dehydratase H5C80_12895 ENOG4105C30 Nad-dependent epimerase dehydratase H5C80_12900 ENOG4105FGF GDP-mannose mannosyl hydrolase H5C80_12905 ENOG4106CD9 glycosyl transferase group 1 H5C80_12910 ENOG4105CJT Mannose-1-phosphate guanylyltransferase H5C80_12915 ENOG4107QKV phosphomannomutase H5C80_12920 ENOG4105D3Q Sugar transferase H5C80_12925 ENOG4105PSV Polysaccharide Biosynthesis Protein H5C80_12930 ENOG4105C74 pyruvyl transferase H5C80_12935 ENOG4107T8Q Glycosyl transferase (Group 1 H5C80_12940 ENOG4105G1A colanic acid biosynthesis protein H5C80_12945 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase H5C80_12980 ENOG4107QRS glycosyltransferase group 2 family protein H5C80_13010 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) H5C80_13050 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) H5C80_13055 ENOG4105ECC imidazole-glycerol-phosphate dehydratase H5C80_13080 ENOG4105VTW prevent-host-death family H5C80_13085 ENOG4105KRQ Addiction module toxin, Txe YoeB family H5C80_13090 ENOG4107SRH Nad-dependent epimerase dehydratase H5C80_13095 ENOG4105EQ1 Transcriptional regulator H5C80_13105 ENOG4105CUB amino acid H5C80_13110 ENOG4105CUC YeeE YedE family protein H5C80_13120 ENOG4105CJB Exodeoxyribonuclease I H5C80_13125 ENOG4105DZ1 carboxypeptidase H5C80_13135 ENOG4105DR8 Membrane H5C80_13170 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles H5C80_13180 ENOG4108YGG dna repair protein H5C80_13185 ENOG4105MFG Antirestriction protein H5C80_13190 ENOG4106H6R UPF0380 protein H5C80_13210 ENOG4108YIV H5C80_13215 ENOG4108F5E vimentin H5C80_13235 ENOG4105D70 Integrase catalytic subunit H5C80_13240 ENOG4105F5W AtP-binding protein H5C80_13275 ENOG4108YXQ IS66 Orf2 family protein H5C80_13320 ENOG41080QX K07048 phosphotriesterase-related protein H5C80_13335 ENOG4108RVA ribokinase H5C80_13345 ENOG4108YZT Adenosylcobinamide kinase H5C80_13360 ENOG4108PXI ErfK YbiS YcfS YnhG H5C80_13370 ENOG4106P55 Transcriptional regulator H5C80_13375 ENOG4107R11 Transcriptional regulator H5C80_13385 ENOG4105UQX Mate efflux family protein H5C80_13395 ENOG4105CDY transcriptional regulatory protein H5C80_13400 ENOG4105FYV Amp nucleosidase H5C80_13405 ENOG4105CSH Transporter H5C80_13420 ENOG4105TNG K13735 adhesin invasin H5C80_13425 ENOG4107ZSV Receptor H5C80_13430 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase H5C80_13450 ENOG4105C0W non-ribosomal peptide synthetase H5C80_13465 ENOG4105BZ1 (ABC) transporter H5C80_13470 ENOG4105EYM Major Facilitator superfamily H5C80_13500 ENOG4108MEK Metal-binding protein YodA H5C80_13515 ENOG4105VT2 5-hydroxyisourate hydrolase H5C80_13520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family H5C80_13525 ENOG4107ZY3 Histidine kinase H5C80_13535 ENOG4105ZIT Porin Gram-negative type H5C80_13545 ENOG4105EST Metal Dependent Phosphohydrolase H5C80_13550 ENOG4105DVF Cytosine-specific methyltransferase H5C80_13555 ENOG41090BB DNA mismatch endonuclease (vsr) H5C80_13560 ENOG4105FDR Membrane H5C80_13565 ENOG4105CKW Inner membrane protein yedI H5C80_13570 ENOG4105VNZ cytoplasmic protein H5C80_13585 ENOG4105YX3 cellular response to acidity H5C80_13595 ENOG4107TKS colanic acid capsular biosynthesis activation protein A H5C80_13600 ENOG4105D19 Role in flagellar biosynthesis (By similarity) H5C80_13610 ENOG4105CN7 Flagellar biosynthetic protein FliP H5C80_13615 ENOG4105K0P flagellar biosynthesis protein H5C80_13620 ENOG4105DD5 Flagellar motor switch protein H5C80_13625 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) H5C80_13630 ENOG4107ZI8 flagellar basal body-associated protein flil H5C80_13635 ENOG4105WF4 Flagellar hook-length control protein H5C80_13640 ENOG4105GSA Flagellar export protein flij H5C80_13645 ENOG4108JIR Flagellum-specific ATP synthase H5C80_13650 ENOG41090PJ Flagellar assembly protein H5C80_13655 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) H5C80_13660 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) H5C80_13670 ENOG410814C multidrug resistance protein H5C80_13675 ENOG4108V1U phospholipid-binding protein H5C80_13680 ENOG4108UQN AraC family transcriptional regulator H5C80_13700 ENOG4105D7V transposase H5C80_13705 ENOG4108RAV Conserved protein H5C80_13715 ENOG41066VF YeeE YedE family protein H5C80_13720 ENOG4108W9D (LipO)protein H5C80_13725 ENOG4105E5K Alpha-amylase H5C80_13735 ENOG4105MQ3 flagellar protein FliS H5C80_13740 ENOG4105DTS flagellar hook-associated H5C80_13745 ENOG4105I03 Flagellin H5C80_13750 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) H5C80_13755 ENOG4108M9K flagella biosynthesis protein FliZ H5C80_13760 ENOG4105EAB amino acid AbC transporter H5C80_13765 ENOG4105K6H D-cysteine desulfhydrase H5C80_13770 ENOG4105E5Q amino acid AbC transporter H5C80_13775 ENOG4105CDA abc transporter atp-binding protein H5C80_13780 ENOG4105VJY transcriptional regulator H5C80_13785 ENOG4105XVG cytoplasmic protein H5C80_13795 ENOG4105WH1 Two component transcriptional regulator luxr family H5C80_13825 ENOG4106RHG Yeca family H5C80_13830 ENOG4105E0U tyrosine-specific transport protein H5C80_13835 ENOG4105VVZ metal-binding protein H5C80_13840 ENOG41090A1 ferritin H5C80_13845 ENOG4105P23 (LipO)protein H5C80_13855 ENOG4105N4N Protein of unknown function (DUF2766) H5C80_13860 ENOG4108UEC Ferritin-like protein H5C80_13865 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator H5C80_13870 ENOG4105C2J ABC transporter H5C80_13875 ENOG4105CNN ABC, transporter H5C80_13880 ENOG4108K4C ec 3.1.3.12 H5C80_13885 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase H5C80_13890 ENOG4108VA4 Universal stress protein H5C80_13900 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region H5C80_13905 ENOG4107RD7 Flagellar Motor Protein, MotA H5C80_13910 ENOG4105ER2 Ompa motb domain protein H5C80_13915 ENOG4105CBS Chea signal transduction histidine kinase H5C80_13920 ENOG4108V3W Chemotaxis protein, CheW H5C80_13925 ENOG4105C8Q Methyl-accepting chemotaxis H5C80_13930 ENOG4105C8Q Methyl-accepting chemotaxis H5C80_13935 ENOG4105BZU Histidine kinase H5C80_13945 ENOG4108VYJ response regulator receiver protein H5C80_13950 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) H5C80_13955 ENOG4105D00 flagellar biosynthetic protein flhB H5C80_13960 ENOG4105D7B Flagellar biosynthesis protein flha H5C80_13965 ENOG4105W13 flagellar protein H5C80_13970 ENOG4105C75 arginyL-tRNA synthetase H5C80_13975 ENOG4106ZCM YecM protein H5C80_13985 ENOG4105CUW cytochrome C-TYPE protein H5C80_13990 ENOG4107QY8 reductase H5C80_14005 ENOG4105WJG Glutathione H5C80_14010 ENOG41081XQ Conserved Protein H5C80_14015 ENOG4105D3W isochorismatase H5C80_14025 ENOG4108TIT dATP pyrophosphohydrolase H5C80_14030 ENOG4105CDY transcriptional regulatory protein H5C80_14040 ENOG4107S01 Repressor protein MetJ H5C80_14060 ENOG4105FAV ABC, transporter H5C80_14070 ENOG4105NXV High-affinity zinc uptake system protein H5C80_14075 ENOG4105DR5 peptidase H5C80_14080 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase H5C80_14085 ENOG4105CA9 Pyruvate kinase H5C80_14090 ENOG4106KNT transcriptional regulator H5C80_14095 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase H5C80_14100 ENOG4105C01 Dihydroxy-acid dehydratase H5C80_14105 ENOG4108UHU Aldolase H5C80_14115 ENOG4105X2V dna damage-inducible protein H5C80_14125 ENOG4108Q2J Inner membrane protein YebE H5C80_14130 ENOG4105CUG Oligopeptidase b H5C80_14135 ENOG4105UMD exodeoxyribonuclease X H5C80_14140 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase H5C80_14145 ENOG4105MPK DNA polymerase III subunit theta H5C80_14150 ENOG4105FXM Copper resistance protein H5C80_14155 ENOG4108PNC copper resistance H5C80_14160 ENOG4105NKT exported protein H5C80_14165 ENOG4108R1E Serine threonine protein phosphatase 1 H5C80_14170 ENOG4105UVW uncharacterized protein yebW H5C80_14175 ENOG4105WT8 Protein of unknown function (DUF1480) H5C80_14185 ENOG4105DY2 Paraquat-inducible protein b H5C80_14190 ENOG4105H2K paraquat-inducible protein a H5C80_14195 ENOG4108ZGC gaf domain protein H5C80_14205 ENOG4105CN1 protease H5C80_14215 ENOG4108RS6 transposase H5C80_14225 ENOG41064WM Uncharacterized protein YcgX H5C80_14230 ENOG4108XDN Transcriptional regulator H5C80_14235 ENOG4105BZU Histidine kinase H5C80_14240 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component H5C80_14245 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB H5C80_14255 ENOG410738I uncharacterized protein ymgC H5C80_14260 ENOG4105BZU Histidine kinase H5C80_14275 ENOG410658X H5C80_14310 ENOG4107QMS site-determining protein H5C80_14320 ENOG4105S66 prophage protein H5C80_14325 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium H5C80_14335 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase H5C80_14340 ENOG4108ZZ3 UPF0260 protein H5C80_14350 ENOG4105KT5 UmuD protein H5C80_14355 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) H5C80_14365 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) H5C80_14375 ENOG4105ED1 spovr family H5C80_14385 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) H5C80_14395 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A H5C80_14405 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) H5C80_14420 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase H5C80_14425 ENOG4108BSC Methyltransferase H5C80_14430 ENOG4105E0A ABC, transporter H5C80_14435 ENOG4105EHG Permease protein H5C80_14440 ENOG4105S10 periplasmic binding protein H5C80_14445 ENOG4105E53 ec 3.2.1.28 H5C80_14450 ENOG4105VDH Dihydroxyacetone kinase H5C80_14455 ENOG4108UTZ Dihydroxyacetone kinase H5C80_14460 ENOG4105CMT Dihydroxyacetone kinase H5C80_14465 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family H5C80_14475 ENOG4105C3G gtp-binding protein H5C80_14485 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria H5C80_14490 ENOG4105CHH sulfate transporter H5C80_14495 ENOG4105C5T Phosphoribosyl pyrophosphate synthase H5C80_14520 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) H5C80_14525 ENOG4108YY7 Invasion gene expression up-regulator SirB H5C80_14530 ENOG41063JG Transcriptional regulator H5C80_14545 ENOG4105EWV Sodium calcium exchanger membrane region H5C80_14550 ENOG4105WS7 Cation transport regulator H5C80_14555 ENOG4108NH8 Cation transport protein H5C80_14560 ENOG41090EX DsrE family H5C80_14565 ENOG4105ID0 Putative invasin H5C80_14570 ENOG4105WH1 Two component transcriptional regulator luxr family H5C80_14575 ENOG4105BZU Histidine kinase H5C80_14580 ENOG4105DQQ Major facilitator superfamily MFS_1 H5C80_14585 ENOG4105CRU nitrate reductase, alpha subunit H5C80_14590 ENOG4108IUE nitrate reductase beta subunit H5C80_14595 ENOG4105R3A Nitrate reductase H5C80_14600 ENOG41076YT nitrate reductase, gamma subunit H5C80_14620 ENOG4105CIY formyltetrahydrofolate deformylase H5C80_14630 ENOG4105D78 K07001 NTE family protein H5C80_14635 ENOG4105I93 response regulator H5C80_14640 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase H5C80_14645 ENOG4108SAU DNA-binding protein H-ns H5C80_14650 ENOG4107104 thymidine kinase H5C80_14655 ENOG4105C0A alcohol dehydrogenase H5C80_14660 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein H5C80_14670 ENOG4108J59 Extracellular solute-binding protein, family 5 H5C80_14675 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component H5C80_14680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component H5C80_14685 ENOG4105C3U ABC transporter H5C80_14690 ENOG4108JQ7 (ABC) transporter H5C80_14710 ENOG4107SVH Potassium channel protein H5C80_14715 ENOG4105K9H YciI-like protein H5C80_14720 ENOG410822N TonB family H5C80_14725 ENOG4105NAU thioesterase Superfamily protein H5C80_14745 ENOG4105EIF outer membrane protein W H5C80_14750 ENOG4108N8X transition metal ion binding H5C80_14755 ENOG4108Z9Z response to DNA damage stimulus H5C80_14775 ENOG4105DK0 Indole-3-glycerol phosphate synthase H5C80_14780 ENOG4108EFP Anthranilate synthase component II H5C80_14785 ENOG4105CRQ synthase (Component I) H5C80_14795 ENOG4105DB7 PHP domain protein H5C80_14800 ENOG4107RTD sua5 ycio yrdc ywlc family protein H5C80_14805 ENOG4105EG3 transmembrane signal peptide protein H5C80_14810 ENOG4105FE9 pseudouridine synthase H5C80_14825 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase H5C80_14830 ENOG4105UBK short-chain dehydrogenase reductase H5C80_14835 ENOG4105ERU peptidase H5C80_14840 ENOG4105RKX Protein of unknown function (DUF2498) H5C80_14845 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) H5C80_14850 ENOG4107R11 Transcriptional regulator H5C80_14870 ENOG4107QM5 aconitate hydratase H5C80_14880 ENOG4105EYK Phosphatidylglycerophosphatase B H5C80_14885 ENOG4105Q4A inner membrane protein yciS H5C80_14890 ENOG4105CFV Tetratricopeptide repeat protein H5C80_14900 ENOG4108ZJT translation initiation factor, Sui1 H5C80_14910 ENOG4105N2W Transcriptional regulator H5C80_14915 ENOG410643D UPF0509 protein H5C80_14920 ENOG4105BZU Histidine kinase H5C80_14930 ENOG4108IEC Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity) H5C80_14935 ENOG4105Q4T oxidoreductase H5C80_14940 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH H5C80_14945 ENOG41067SE Tetr family transcriptional regulator H5C80_14950 ENOG4105C1P efflux transporter, rnd family, mfp subunit H5C80_14955 ENOG4105BZS acriflavin resistance protein H5C80_14960 ENOG4105ENJ RND efflux system, outer membrane lipoprotein H5C80_14965 ENOG4105C2C drug resistance transporter, Bcr CflA H5C80_14970 ENOG4108JQ2 peptide transport system atp-binding protein H5C80_14975 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein H5C80_14980 ENOG4108EU3 peptide transport system, permease H5C80_14985 ENOG4108I5W peptide transport system, permease protein H5C80_14990 ENOG4108HIY periplasmic H5C80_14995 ENOG4105N0E Protein of unknown function (DUF2543) H5C80_15000 ENOG4105CUB amino acid H5C80_15010 ENOG4105CFQ glutamine synthetase H5C80_15015 ENOG4108Z86 Glutamine amidotransferase H5C80_15020 ENOG4107VRI Transcriptional regulator H5C80_15025 ENOG4105C26 Dehydrogenase H5C80_15030 ENOG4105CJP fad dependent oxidoreductase H5C80_15035 ENOG4108JPW Aminotransferase H5C80_15040 ENOG4105E51 psp operon transcriptional activator H5C80_15045 ENOG41087YS Phage shock protein A H5C80_15050 ENOG4105YYT phage shock protein B H5C80_15055 ENOG4105FM1 phage shock protein C H5C80_15060 ENOG4105NNG Peripheral inner membrane phage-shock protein H5C80_15065 ENOG4105K8Z Phage shock protein H5C80_15070 ENOG4107QW3 Sucrose phosphorylase H5C80_15075 ENOG4105WEM extracellular solute-binding protein H5C80_15080 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component H5C80_15085 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component H5C80_15090 ENOG4107RRD Dehydrogenase H5C80_15095 ENOG4107TYA transient receptor potential locus H5C80_15100 ENOG4105CK5 oxidoreductase H5C80_15105 ENOG4105C71 hydrolase family 65, central catalytic H5C80_15110 ENOG4107URF beta-phospho-glucomutase H5C80_15120 ENOG4107EFV Outer membrane protein G H5C80_15125 ENOG4105FKQ transcriptional regulator H5C80_15130 ENOG4105CM6 amino acid regulated cytosolic protein H5C80_15140 ENOG4108JU8 Transcriptional regulator H5C80_15145 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) H5C80_15150 ENOG4107S8C mandelate racemase muconate lactonizing H5C80_15155 ENOG4105KXI murein peptide amidase A H5C80_15175 ENOG4105ENX hydrolase H5C80_15180 ENOG4105EQ2 LysR family Transcriptional regulator H5C80_15185 ENOG4107QSI ABC, transporter H5C80_15190 ENOG4105D64 Mechanosensitive ion channel H5C80_15195 ENOG4105S5I Membrane H5C80_15200 ENOG4105Q9Y Universal stress protein H5C80_15205 ENOG4105DS0 Transcriptional regulator, Crp Fnr family H5C80_15210 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) H5C80_15220 ENOG4105R1U AraC Family Transcriptional Regulator H5C80_15235 ENOG4108DG9 Smr protein MutS2 H5C80_15240 ENOG4105BZU Histidine kinase H5C80_15250 ENOG4105C1J atp-dependent rna helicase H5C80_15260 ENOG4107R08 Integrase H5C80_15265 ENOG4107160 Rac prophage H5C80_15270 ENOG41070YT Rac prophage H5C80_15275 ENOG4106YAH restriction alleviation and modification enhancement H5C80_15280 ENOG4108PNI recT protein H5C80_15285 ENOG41076J9 exonuclease VIII H5C80_15295 ENOG4107C82 Rac prophage H5C80_15315 ENOG410649Z repressor H5C80_15320 ENOG4105W7J DNA binding H5C80_15330 ENOG4105ZTP Protein of unknown function (DUF1376) H5C80_15335 ENOG4105JBR DNA replication protein H5C80_15355 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) H5C80_15360 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) H5C80_15380 ENOG4105RWQ Protein of unknown function (DUF1364) H5C80_15415 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) H5C80_15420 ENOG4108ES9 ParB domain protein nuclease H5C80_15535 ENOG4108X9F tail fiber protein H5C80_15545 ENOG4105CC5 ABC transporter H5C80_15550 ENOG4105CC5 ABC transporter H5C80_15555 ENOG4105DIK (ABC) transporter H5C80_15565 ENOG4108RW8 Universal stress protein F H5C80_15570 ENOG4105FCK Membrane H5C80_15575 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) H5C80_15580 ENOG4105IKK cytoplasmic protein H5C80_15585 ENOG41090X5 Heat shock protein hslJ H5C80_15590 ENOG4105C5I Dehydrogenase H5C80_15595 ENOG4107H52 Dicarboxylate transport H5C80_15600 ENOG410689M (LipO)protein H5C80_15605 ENOG4105WXT Conserved Protein H5C80_15610 ENOG4108WFR AraC Family Transcriptional Regulator H5C80_15615 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein H5C80_15620 ENOG4108Z0R Transferase H5C80_15625 ENOG4107S5I aldo keto reductase H5C80_15630 ENOG4108RS6 transposase H5C80_15640 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase H5C80_15645 ENOG4108HPI phosphatidate Cytidylyltransferase H5C80_15650 ENOG4105E8V Alpha Beta Hydrolase Fold protein H5C80_15655 ENOG41077RS Phosphatase H5C80_15665 ENOG4105CQ7 ATP-dependent helicase H5C80_15670 ENOG4107DB1 DUF218 domain H5C80_15675 ENOG4105C26 Dehydrogenase H5C80_15680 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase H5C80_15685 ENOG4105CPW cytochrome b561 H5C80_15690 ENOG4105UPP uncharacterized protein ydcA H5C80_15695 ENOG4107NK6 Hok/gef family H5C80_15700 ENOG4105C8Q Methyl-accepting chemotaxis H5C80_15705 ENOG4105DDW LysR family Transcriptional regulator H5C80_15710 ENOG4105E32 cytoplasmic protein H5C80_15720 ENOG4105Z2P Protein of unknown function (DUF465) H5C80_15725 ENOG4108Z9I -acetyltransferase H5C80_15730 ENOG4107WE3 acetyltransferase YdcK H5C80_15735 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein H5C80_15740 ENOG41088CC tellurite resistance protein tehB H5C80_15745 ENOG4108KKZ (LipO)protein H5C80_15750 ENOG4105DKK Benzoate H5C80_15755 ENOG4108JCI Transcriptional regulator H5C80_15760 ENOG4105CFP Peptidase U32 H5C80_15765 ENOG4105RR0 Protein of unknown function (DUF2554) H5C80_15775 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin H5C80_15780 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family H5C80_15785 ENOG4107TYH extracellular solute-binding protein family 1 H5C80_15790 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) H5C80_15795 ENOG4105D81 ABC transporter, permease H5C80_15815 ENOG410654E Membrane H5C80_15820 ENOG4105R71 cytoplasmic protein H5C80_15825 ENOG4108T9Y Inner membrane protein ydcZ H5C80_15830 ENOG4108Z7F N-acetyltransferase H5C80_15835 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein H5C80_15840 ENOG4108WYP Transcriptional regulator H5C80_15845 ENOG4105CHB tonB-dependent Receptor H5C80_15850 ENOG4108NS2 receptor H5C80_15855 ENOG4105C85 amino acid H5C80_15930 ENOG4105EUZ Beta-lactamase domain protein H5C80_15940 ENOG4108MEJ flavin reductase domain protein H5C80_15945 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase H5C80_15950 ENOG4105JAB phenazine biosynthesis protein, phzf family H5C80_15955 ENOG4105D0D Nitrate reductase 2, gamma subunit H5C80_15960 ENOG4108NZN Respiratory nitrate reductase 2 delta chain H5C80_15965 ENOG4108IUE nitrate reductase beta subunit H5C80_15970 ENOG4105CRU nitrate reductase, alpha subunit H5C80_15975 ENOG4107QND Nitrite extrusion protein H5C80_15980 ENOG4105RPH Inner membrane protein YddG H5C80_15990 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein H5C80_15995 ENOG4108MG3 formate dehydrogenase H5C80_16000 ENOG4108RS6 transposase H5C80_16005 ENOG41084S7 Plasmid maintenance system antidote protein H5C80_16010 ENOG4105DQ4 alcohol dehydrogenase H5C80_16020 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein H5C80_16025 ENOG4105TPS biofilm-dependent modulation protein H5C80_16030 ENOG4108Z9K Osmotically inducible protein H5C80_16035 ENOG4105BZU Histidine kinase H5C80_16050 ENOG4105F32 YngK protein H5C80_16055 ENOG4105E5D amino acid H5C80_16060 ENOG4105CVK Glutamate decarboxylase H5C80_16065 ENOG4107RAN Peptidase, M16 H5C80_16070 ENOG4105PE1 Receptor H5C80_16075 ENOG4105CQ0 ABC transporter H5C80_16085 ENOG4105C4X radical SAM domain protein H5C80_16090 ENOG4105ENH Sulfatase H5C80_16095 ENOG4108NKV transcriptional regulator H5C80_16105 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit H5C80_16110 ENOG4106PIH fimbrial-like protein ydeQ H5C80_16115 ENOG4106318 fimbrial-like protein YdeR H5C80_16120 ENOG4108WDE Fimbrial protein H5C80_16125 ENOG4105CW0 outer membrane usher protein H5C80_16135 ENOG4108RQP Major type 1 subunit fimbrin H5C80_16145 ENOG4105CAF HipA N-terminal domain protein H5C80_16150 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein H5C80_16195 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound H5C80_16205 ENOG4105FFC UPF0187 protein H5C80_16215 ENOG4105BZU Histidine kinase H5C80_16220 ENOG4105M0C cytoplasmic protein H5C80_16225 ENOG4105CSV Glutaminase H5C80_16230 ENOG4105C26 Dehydrogenase H5C80_16235 ENOG4105EGI Transcriptional regulator H5C80_16255 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes H5C80_16260 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF H5C80_16265 ENOG4106DNR multiple antibiotic resistance protein H5C80_16270 ENOG4108594 Permease of the drug metabolite transporter H5C80_16275 ENOG4105E5W Transporter H5C80_16285 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria H5C80_16290 ENOG4108YDI single-species biofilm formation on inanimate substrate H5C80_16295 ENOG4105DGW oligopeptidase A H5C80_16300 ENOG4105EMU Dehydrogenase H5C80_16305 ENOG4107XBN GntR Family Transcriptional Regulator H5C80_16310 ENOG41061EV selenium-binding protein YdfZ H5C80_16315 ENOG4105DEI Mannitol dehydrogenase H5C80_16330 ENOG4105W3V DNA-binding, transcriptional regulator H5C80_16335 ENOG4105MN3 Resolvase H5C80_16340 ENOG4105UZW Tail fiber assembly protein H5C80_16345 ENOG4108X9F tail fiber protein H5C80_16425 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) H5C80_16460 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation H5C80_16465 ENOG4106IAW H5C80_16480 ENOG4105VEQ Cold shock protein H5C80_16485 ENOG4108YV9 Protein of unknown function (DUF2514) H5C80_16500 ENOG4105QFS Lysis protein S homolog from lambdoid prophage H5C80_16505 ENOG4105VEQ Cold shock protein H5C80_16515 ENOG4105HGD Antitermination protein H5C80_16520 ENOG4108MXB Protein of unknown function (DUF968) H5C80_16535 ENOG4105WI6 cell killing protein encoded within cryptic prophage H5C80_16565 ENOG41087BU transcriptional repressor DicA H5C80_16590 ENOG4106G8A Qin prophage H5C80_16605 ENOG4107R08 Integrase H5C80_16615 ENOG4105CPQ Dehydrogenase H5C80_16620 ENOG4105CXK mandelate racemase muconate lactonizing H5C80_16635 ENOG4108MK9 spermidine N(1)-acetyltransferase H5C80_16645 ENOG4105KBG Protein of unknown function (DUF1161) H5C80_16670 ENOG4105C3J Cysteine desulfurase H5C80_16675 ENOG4105QAX Iron-sulfur H5C80_16680 ENOG4107KGK dmso reductase anchor subunit H5C80_16685 ENOG4108NEM leader-binding protein dmsD H5C80_16695 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) H5C80_16700 ENOG4105DAG ROK family H5C80_16705 ENOG4106NZI LysR family Transcriptional regulator H5C80_16710 ENOG4105D94 Major Facilitator Superfamily H5C80_16725 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap H5C80_16740 ENOG4105DSF transport protein H5C80_16745 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) H5C80_16750 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) H5C80_16755 ENOG4105C5D exported protein H5C80_16760 ENOG4105D5Q Arginine ornithine antiporter H5C80_16770 ENOG4105RA2 Membrane H5C80_16775 ENOG4107EXC regulatoR H5C80_16780 ENOG4105JJR Histidine kinase H5C80_16790 ENOG4105C9Q fumarate hydratase class II H5C80_16795 ENOG4107GFK fumarate H5C80_16800 ENOG4105EIP mannose-6-phosphate isomerase H5C80_16805 ENOG4106J39 exported protein H5C80_16810 ENOG4108QNI outer membrane porin protein H5C80_16815 ENOG4105CT4 transporter H5C80_16820 ENOG4105CNT hydrolase family 2 H5C80_16825 ENOG4105XEA Tetr family transcriptional regulator H5C80_16830 ENOG4107ZQV short-chain dehydrogenase reductase H5C80_16835 ENOG4107P2S Transcriptional regulator H5C80_16840 ENOG4105CI1 PTS System H5C80_16845 ENOG4105C87 Aminotransferase class I and II H5C80_16855 ENOG4105D9R oxidoreductase H5C80_16860 ENOG4106C6R beta-lactam resistance protein H5C80_16865 ENOG4105QZ5 OriC-binding nucleoid-associated protein H5C80_16870 ENOG4105M9B inner membrane protein ydgK H5C80_16895 ENOG4108UQQ Electron transport complex H5C80_16905 ENOG4105CSM endonuclease III H5C80_16910 ENOG4105DUX Transporter H5C80_16915 ENOG4108K3A Glutathione S-transferase H5C80_16920 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) H5C80_16935 ENOG410642K Lysozyme inhibitor H5C80_16945 ENOG4108XTF Outer Membrane Lipoprotein H5C80_16960 ENOG4105Y49 secretion protein, HlyD family H5C80_16965 ENOG4105DSW Fusaric acid resistance protein H5C80_16970 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) H5C80_16975 ENOG4107RGM aldo keto reductase H5C80_16980 ENOG4105XZD Fe-S protein H5C80_16985 ENOG4108WUH Transcriptional regulator, TetR family H5C80_16990 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase H5C80_16995 ENOG4108UYE Lactoylglutathione lyase H5C80_17005 ENOG4107QRT dEAD DEAH box helicase H5C80_17010 ENOG4105M2J Glutaredoxin H5C80_17015 ENOG4105K4H Nlp p60 protein H5C80_17020 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) H5C80_17025 ENOG4105F27 Major Facilitator H5C80_17040 ENOG4105F52 Transcriptional regulator H5C80_17045 ENOG4105CZQ inner membrane transport protein YdhC H5C80_17050 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase H5C80_17055 ENOG4108R6K riboflavin synthase, subunit alpha H5C80_17080 ENOG4105N0V mono-oxygenase ydhR H5C80_17085 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain H5C80_17090 ENOG4108Y7C Conserved Protein H5C80_17095 ENOG4108NWD Cytochrome H5C80_17100 ENOG4108393 oxidoreductase Fe-S subunit H5C80_17105 ENOG4105JVW H5C80_17110 ENOG4105WE2 aldehyde ferredoxin oxidoreductase H5C80_17115 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein H5C80_17120 ENOG4105RFR Protein of unknown function (DUF2767) H5C80_17125 ENOG4105CA9 Pyruvate kinase H5C80_17130 ENOG4105KMX major outer membrane lipoprotein H5C80_17135 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein H5C80_17150 ENOG4105JRK feS assembly protein SufD H5C80_17155 ENOG4105C3K feS assembly ATPase SufC H5C80_17160 ENOG4105DIW FeS assembly protein SUFB H5C80_17165 ENOG4108Z4V iron-sulfur cluster assembly H5C80_17170 ENOG410671Z uncharacterized protein ydiH H5C80_17175 ENOG4105KA0 thioesterase Superfamily protein H5C80_17180 ENOG4105CQB FAD linked oxidase domain protein H5C80_17185 ENOG4105IPI Membrane H5C80_17195 ENOG4105SUA Ydil protein H5C80_17200 ENOG4105EMV Major Facilitator H5C80_17205 ENOG4105EMV Major Facilitator H5C80_17220 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) H5C80_17225 ENOG4105C1G acyl-Coa dehydrogenase H5C80_17230 ENOG4105W4W Transcriptional regulator H5C80_17235 ENOG4105CV7 Electron transfer flavoprotein H5C80_17240 ENOG4105C10 Electron transfer flavoprotein H5C80_17245 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase H5C80_17250 ENOG41090P5 ferredoxin-like protein H5C80_17255 ENOG4105CEY Amp-dependent synthetase and ligase H5C80_17260 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) H5C80_17270 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) H5C80_17285 ENOG4108TC0 Diguanylate phosphodiesterase H5C80_17290 ENOG4108QBX (LipO)protein H5C80_17300 ENOG4108V06 Glutathione peroxidase H5C80_17335 ENOG41082NX 50s ribosomal protein l35 H5C80_17340 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) H5C80_17360 ENOG4108NE3 Salt-induced outer membrane protein H5C80_17365 ENOG4105DE4 1-phosphofructokinase H5C80_17370 ENOG4105P10 Uncharacterized protein ydiZ H5C80_17380 ENOG4107PN8 YfeABCD locus regulator H5C80_17385 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 H5C80_17390 ENOG4107K5X Membrane-bound metal-dependent hydrolase H5C80_17395 ENOG4108ETY sodium dicarboxylate symporter H5C80_17405 ENOG4105CH6 catalase H5C80_17410 ENOG410901P UPF0249 protein H5C80_17415 ENOG4105F8D glycoside hydrolase family 4 H5C80_17420 ENOG4105EZV Transcriptional regulator H5C80_17425 ENOG4105VCP PTS System H5C80_17430 ENOG4105CK1 PTS System H5C80_17435 ENOG4105VZJ PTS System H5C80_17440 ENOG4105KKI DNA-binding transcriptional activator OsmE H5C80_17450 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) H5C80_17460 ENOG4108SPG Periplasmic Protein H5C80_17470 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) H5C80_17490 ENOG4105CGK Exodeoxyribonuclease III H5C80_17495 ENOG4108RSN SNARE associated Golgi H5C80_17500 ENOG4108KCW iron-sulfur cluster binding H5C80_17505 ENOG4108N5C SNARE associated Golgi protein-related protein H5C80_17510 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) H5C80_17515 ENOG4105VNH ABC transporter solute-binding protein H5C80_17520 ENOG4105CXZ ABC transporter, permease H5C80_17525 ENOG4108VGW abc transporter atp-binding protein H5C80_17530 ENOG4107RM6 sulfurtransferase H5C80_17535 ENOG4108T9J Cdp-alcohol phosphatidyltransferase H5C80_17540 ENOG4105M6F mutator MutT protein H5C80_17545 ENOG4105MTM Protein of unknown function (DUF1496) H5C80_17550 ENOG4105D82 Glutamate dehydrogenase H5C80_17555 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) H5C80_17560 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) H5C80_17565 ENOG41069NU Nitroreductase H5C80_17570 ENOG4105D07 Signal peptide peptidase, SppA H5C80_17575 ENOG4105HDK L-asparaginase H5C80_17580 ENOG4108RWI nicotinamidase H5C80_17585 ENOG4105VUT cytoplasmic protein H5C80_17595 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase H5C80_17600 ENOG4105DSB aldose 1-epimerase H5C80_17605 ENOG4105CV8 reductase H5C80_17610 ENOG4105GNX MltA-interacting MipA family protein H5C80_17615 ENOG4105CYN Serine protein kinase H5C80_17625 ENOG4106KTS Inner membrane protein yeaI H5C80_17630 ENOG4108KHP Diguanylate cyclase H5C80_17635 ENOG4108KXH Ybak prolyl-tRNA synthetase associated H5C80_17650 ENOG4105R1U AraC Family Transcriptional Regulator H5C80_17655 ENOG4105DJ2 Major Facilitator Superfamily H5C80_17660 ENOG4105K78 MarR family Transcriptional regulator H5C80_17665 ENOG4105UCG Domain of unknown function (DUF333) H5C80_17670 ENOG410620I Diguanylate cyclase H5C80_17675 ENOG4106G4W H5C80_17685 ENOG4105Y3U Transglycosylase-associated protein H5C80_17690 ENOG4105YP6 Domain of unknown function (DUF1869) H5C80_17695 ENOG4108YS1 cytoplasmic protein H5C80_17705 ENOG4105EJC lysr family transcriptional regulator H5C80_17710 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) H5C80_17715 ENOG4105C94 Transporter H5C80_17720 ENOG4105DVW rieske (2Fe-2S) H5C80_17725 ENOG4105E3J oxidoreductase H5C80_17730 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) H5C80_17735 ENOG4105CEY Amp-dependent synthetase and ligase H5C80_17740 ENOG4105Y4Z Outer Membrane Lipoprotein H5C80_17745 ENOG41072GX Peptidase M22 Glycoprotease H5C80_17750 ENOG4105DVT helicase H5C80_17755 ENOG4105M4H endoribonuclease L-psp H5C80_17760 ENOG4105V2F Uncharacterized protein yoac H5C80_17770 ENOG4105CRQ synthase (Component I) H5C80_17780 ENOG4105EJQ L-serine dehydratase H5C80_17785 ENOG4107XTP (EAL) domain protein H5C80_17790 ENOG4105EE5 Membrane protein terC H5C80_17795 ENOG4105DAS pts system H5C80_17800 ENOG4105ETZ PTS System H5C80_17805 ENOG4105F3R pts system mannose fructose sorbose family iid H5C80_17820 ENOG4105DHI Methyltransferase H5C80_17835 ENOG4105Q3Y exported protein H5C80_17845 ENOG4105TIK H5C80_17850 ENOG4105J4Q Transcriptional regulator H5C80_17855 ENOG4105C0R drug resistance transporter emrb qaca subfamily H5C80_17860 ENOG4108RS6 transposase H5C80_17875 ENOG4108RS6 transposase H5C80_17880 ENOG4108HMX isocitrate dehydrogenase (NADP) H5C80_17890 ENOG4108C33 Resolvase H5C80_17900 ENOG4108US3 tail fiber assembly H5C80_17910 ENOG4105Y9F tail fiber protein H5C80_17915 ENOG4105Y0G tail protein H5C80_17920 ENOG4108T86 baseplate J family protein H5C80_17940 ENOG4108NKR DNA circulation protein H5C80_17960 ENOG4105TKZ Tail Sheath H5C80_18005 ENOG4105EFC phage portal protein HK97 family H5C80_18015 ENOG4105CAR Terminase, large subunit H5C80_18030 ENOG4105QYK bacteriophage lambda Bor protein homolog H5C80_18065 ENOG4108MXB Protein of unknown function (DUF968) H5C80_18075 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) H5C80_18105 ENOG4108S1U H5C80_18110 ENOG41078CG DNA-binding transcriptional regulator H5C80_18115 ENOG4105RDA repressor H5C80_18120 ENOG4107712 H5C80_18130 ENOG4105H40 H5C80_18135 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) H5C80_18140 ENOG4108R7K Metal Dependent Phosphohydrolase H5C80_18145 ENOG4105QYW Excisionase-like protein from lambdoid prophage 14 H5C80_18150 ENOG4108I1J Integrase H5C80_18165 ENOG4108HMX isocitrate dehydrogenase (NADP) H5C80_18170 ENOG4108R99 pseudouridine synthase H5C80_18190 ENOG4107QTF adenylosuccinate lyase H5C80_18195 ENOG4105XJC Two component transcriptional regulator (Winged helix family H5C80_18200 ENOG4105IFJ Histidine kinase H5C80_18225 ENOG4105IM0 capsid protein H5C80_18295 ENOG4105EZE Cupin 4 family protein H5C80_18305 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) H5C80_18315 ENOG4105UZW Tail fiber assembly protein H5C80_18320 ENOG4108X9F tail fiber protein H5C80_18410 ENOG4105EFC phage portal protein HK97 family H5C80_18425 ENOG4105CAR Terminase, large subunit H5C80_18530 ENOG4105DFP Integrase H5C80_18560 ENOG4105QFS Lysis protein S homolog from lambdoid prophage H5C80_18585 ENOG4105KSK (crossover) junction endodeoxyribonuclease H5C80_18590 ENOG4108MXB Protein of unknown function (DUF968) H5C80_18670 ENOG4106G8A Qin prophage H5C80_18675 ENOG41076J9 exonuclease VIII H5C80_18685 ENOG4108I1J Integrase H5C80_18690 ENOG4105D38 putrescine abc transporter H5C80_18695 ENOG4107RUE extracellular solute-binding protein family 1 H5C80_18710 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) H5C80_18720 ENOG4105D60 lipoprotein releasing system transmembrane protein H5C80_18725 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) H5C80_18730 ENOG4105D60 lipoprotein releasing system transmembrane protein H5C80_18735 ENOG4105IQC Inner membrane protein YcfT H5C80_18740 ENOG4108JA2 transcriptioN-repair coupling factor H5C80_18745 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein H5C80_18750 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction H5C80_18755 ENOG4108IND Tetr family transcriptional regulator H5C80_18760 ENOG4107MBR 17 kDa surface antigen H5C80_18765 ENOG4105CEP NADH dehydrogenase H5C80_18785 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) H5C80_18790 ENOG41090DQ Lipoprotein H5C80_18795 ENOG4105K59 histidine triad (HIT) protein H5C80_18800 ENOG4105CNM Receptor H5C80_18805 ENOG4105CI1 PTS System H5C80_18810 ENOG4105F8V Hydrolase, tatD family H5C80_18815 ENOG4107QRG dna polymerase iii H5C80_18825 ENOG4105HHA aminodeoxychorismate lyase H5C80_18830 ENOG4105YAZ 4-amino-4-deoxychorismate lyase H5C80_18835 ENOG4108RS6 transposase H5C80_18840 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) H5C80_18845 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) H5C80_18850 ENOG4105CHR reductase H5C80_18855 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase H5C80_18875 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein H5C80_18880 ENOG4108UHJ MAF-like protein H5C80_18885 ENOG4105EI2 Pseudouridine synthase H5C80_18890 ENOG4107QQB Ribonuclease E H5C80_18905 ENOG4105DTJ flagellar hook-associated protein H5C80_18910 ENOG4105E1Q flagellar hook-associated protein H5C80_18915 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj H5C80_18930 ENOG4105CGA flagellar basal-body rod protein FlgG H5C80_18935 ENOG4108KPB Flagellar basal-body rod protein FlgF H5C80_18940 ENOG4105BZE flagellar hook protein, FlgE H5C80_18945 ENOG4105W00 Flagellar hook capping protein H5C80_18950 ENOG4108ZC9 flagellar basal-body rod protein flgc H5C80_18955 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) H5C80_18960 ENOG4105CKS Flagella basal body P-ring formation protein flgA H5C80_18965 ENOG4105M9M anti-sigma28 factor FlgM H5C80_18975 ENOG4105CJR Integral membrane protein (MviN H5C80_18980 ENOG4105EP9 oxidoreductase H5C80_18990 ENOG4105D9U N-acetyltransferase H5C80_19000 ENOG4105E9S glutaredoxin 2 H5C80_19005 ENOG4105F3T (LipO)protein H5C80_19015 ENOG4105MEA DNA damage-inducible protein i H5C80_19020 ENOG4105PVA Biofilm formation regulatory protein BssS H5C80_19025 ENOG4105F76 Sarcosine oxidase H5C80_19030 ENOG4106974 biofilm formation H5C80_19035 ENOG4105DS1 cytochrome b561 H5C80_19040 ENOG4108YYC ycei family H5C80_19050 ENOG4105D1S lipid A biosynthesis H5C80_19060 ENOG4108W47 Acidic protein msyB H5C80_19065 ENOG4105NAC (LipO)protein H5C80_19070 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) H5C80_19085 ENOG4107RZC phospholipase d H5C80_19090 ENOG4108UVJ appr-1-p processing domain protein H5C80_19105 ENOG41090QH cryptic curlin major subunit H5C80_19110 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers H5C80_19115 ENOG41086KC Transcriptional regulator H5C80_19120 ENOG4108XDW curli assembly protein CsgE H5C80_19125 ENOG4108WYR Curli production assembly transport component, CsgF H5C80_19130 ENOG4105P8Q Curli production assembly transport component CsgG H5C80_19135 ENOG4108UQ5 membrane protein YcdZ H5C80_19140 ENOG4107XHZ cytoplasmic chaperone TorD family protein H5C80_19150 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase H5C80_19180 ENOG4105D5M phosphate starvation-inducible protein H5C80_19190 ENOG410650H (LipO)protein H5C80_19200 ENOG4105CK7 Sodium proline symporter H5C80_19210 ENOG4105C26 Dehydrogenase H5C80_19215 ENOG4108R86 Transcriptional regulator H5C80_19240 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) H5C80_19250 ENOG4105C2W permease H5C80_19255 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 H5C80_19265 ENOG4105XH3 H5C80_19270 ENOG4105D6F Phosphatase H5C80_19290 ENOG4107QY8 reductase H5C80_19295 ENOG4105CUW cytochrome C-TYPE protein H5C80_19300 ENOG4106WF9 DNA-binding transcriptional regulator TorR H5C80_19305 ENOG4108SV3 Tmao reductase system periplasmic protein tort H5C80_19310 ENOG4105BZU Histidine kinase H5C80_19315 ENOG4105HEE Binding Domain protein H5C80_19320 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation H5C80_19335 ENOG4105VEQ Cold shock protein H5C80_19340 ENOG41060EU Cold shock-like protein H5C80_19350 ENOG4108Y9B (LipO)protein H5C80_19355 ENOG4108W78 Pfam:DUF1017 H5C80_19360 ENOG4105E3R (LipO)protein H5C80_19365 ENOG4105DAY polysaccharide export protein H5C80_19370 ENOG4107ZF2 Phosphatase H5C80_19375 ENOG4108F2G Chain length determinant protein H5C80_19380 ENOG4105D6F Phosphatase H5C80_19390 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii H5C80_19395 ENOG4105C4M (Ubiquinol oxidase) subunit I H5C80_19400 ENOG4105MVP hydrogenase-1 operon protein HyaF H5C80_19405 ENOG4108VXY Hydrogenase-1 operon protein HyaE H5C80_19410 ENOG4108USZ hydrogenase H5C80_19415 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit H5C80_19420 ENOG4105DPX Hydrogenase, large subunit H5C80_19425 ENOG4105E3S small subunit H5C80_19435 ENOG4108MN8 Membrane H5C80_19440 ENOG4108Z0T Part of a sulfur-relay system (By similarity) H5C80_19445 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 H5C80_19460 ENOG4105K4P CoA-binding domain protein H5C80_19475 ENOG41088T4 Helicase IV H5C80_19480 ENOG410901E Membrane H5C80_19485 ENOG4105EM2 membrane H5C80_19490 ENOG4108RZ1 DNA transformation protein H5C80_19500 ENOG4105UYK outer membrane protein a H5C80_19510 ENOG4105DAN ATP-dependent protease H5C80_19520 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) H5C80_19525 ENOG4108Q2G (LipO)protein H5C80_19530 ENOG4105DY2 Paraquat-inducible protein b H5C80_19535 ENOG4105F1S paraquat-inducible protein a H5C80_19540 ENOG4105C5H ABC transporter H5C80_19550 ENOG4105QVC MOSC domain-containing protein H5C80_19555 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) H5C80_19565 ENOG4108UZX fmn reductase H5C80_19570 ENOG4105GVF (ABC) transporter H5C80_19575 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) H5C80_19580 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component H5C80_19590 ENOG4105CD8 aminopeptidase N H5C80_19605 ENOG4105FCK Membrane H5C80_19610 ENOG4105CGF Aromatic amino acid aminotransferase H5C80_19615 ENOG4105C5X domain protein H5C80_19620 ENOG4105EAQ (twin-arginine translocation) pathway signal H5C80_19625 ENOG4105DIT ErfK YbiS YcfS YnhG family protein H5C80_19630 ENOG4108RS6 transposase H5C80_19640 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) H5C80_19650 ENOG4106371 Methyltransferase H5C80_19655 ENOG4107S90 membrAne H5C80_19660 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups H5C80_19675 ENOG4105T0Z Conserved Protein H5C80_19685 ENOG4105BZ1 (ABC) transporter H5C80_19690 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 H5C80_19700 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) H5C80_19710 ENOG4108K0D peptidase, M48 H5C80_19725 ENOG4107VMU Membrane H5C80_19730 ENOG4105DDY UPF0142 protein ycaO H5C80_19735 ENOG4105TMB Formate nitrite transporter H5C80_19740 ENOG4105C6N Formate acetyltransferase H5C80_19745 ENOG4105F1A Pyruvate formate-lyase H5C80_19755 ENOG4105E5D amino acid H5C80_19765 ENOG4105CHJ isochorismatase hydrolase H5C80_19770 ENOG4107KGK dmso reductase anchor subunit H5C80_19775 ENOG4105QAX Iron-sulfur H5C80_19780 ENOG4107QY8 reductase H5C80_19790 ENOG4105D1H recombination factor protein RarA H5C80_19800 ENOG4105CNU cell division protein FtsK H5C80_19810 ENOG4105C3M thioredoxin reductase H5C80_19815 ENOG4108JJ9 ABC, transporter H5C80_19820 ENOG4108JJ8 (ABC) transporter H5C80_19830 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) H5C80_19840 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit H5C80_19850 ENOG4105VEQ Cold shock protein H5C80_19860 ENOG4105DJY efflux transporter, rnd family, mfp subunit H5C80_19865 ENOG4108MJ5 VirK protein H5C80_19870 ENOG4105CPB ATP-dependent endonuclease of the OLD family H5C80_19875 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) H5C80_19880 ENOG4105DWU Membrane H5C80_19890 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) H5C80_19895 ENOG4105C7K acetolactate synthase H5C80_19900 ENOG4105C5W Aldolase H5C80_19905 ENOG4105CGD Nad-dependent epimerase dehydratase H5C80_19910 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase H5C80_19915 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase H5C80_19925 ENOG41064MM (LipO)protein H5C80_19930 ENOG4105E5Z arginine transporter ATP-binding subunit H5C80_19935 ENOG4106PMH Extracellular solute-binding protein family 3 H5C80_19940 ENOG4105GBT ABC transporter H5C80_19945 ENOG4105DMR ABC, transporter H5C80_19950 ENOG4106TNF Periplasmic binding protein H5C80_19960 ENOG4105RBQ inner membrane protein ybjO H5C80_19965 ENOG4105D38 putrescine abc transporter H5C80_19970 ENOG4105F38 ABC transporter, permease H5C80_19975 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) H5C80_19980 ENOG4107RUE extracellular solute-binding protein family 1 H5C80_19985 ENOG4108RMJ sensory transduction regulator H5C80_19995 ENOG4108DBC nitroreductase H5C80_20000 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress H5C80_20005 ENOG41090BQ Glutaredoxin H5C80_20010 ENOG4105GWF inner membrane protein YbjM H5C80_20020 ENOG4108RFG Tetr family transcriptional regulator H5C80_20025 ENOG4106UW1 Major Facilitator superfamily H5C80_20030 ENOG4108HCJ Hydrolase H5C80_20040 ENOG4107QF7 multi-drug H5C80_20045 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase H5C80_20050 ENOG4107FB0 transcriptional regulator DeoR family H5C80_20055 ENOG4105DZ1 carboxypeptidase H5C80_20060 ENOG4108TGY Glutathione S-transferase H5C80_20065 ENOG4105D8V Glucose sorbosone dehydrogenase H5C80_20070 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway H5C80_20090 ENOG41064RH membrane protein YliF H5C80_20120 ENOG4105D44 asparaginase H5C80_20125 ENOG4105CVM Molybdenum cofactor synthesis domain protein H5C80_20130 ENOG4105D06 uba thif-type nad fad binding protein H5C80_20135 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) H5C80_20140 ENOG4105F1A Pyruvate formate-lyase H5C80_20150 ENOG4108HCJ Hydrolase H5C80_20155 ENOG41072TH Protein of unknown function (DUF1479) H5C80_20160 ENOG4105C5H ABC transporter H5C80_20165 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein H5C80_20170 ENOG4105F4P )-transporter H5C80_20175 ENOG4105KST dependent repressor H5C80_20185 ENOG4108I6E Sulfatase H5C80_20190 ENOG4108T1M outer membrane protein x H5C80_20200 ENOG4107AQZ Membrane H5C80_20210 ENOG4107R0W ABC transporter H5C80_20215 ENOG4105E5Q amino acid AbC transporter H5C80_20220 ENOG4105CDA abc transporter atp-binding protein H5C80_20225 ENOG4105D8X mechanosensitive ion channel H5C80_20235 ENOG4105ZY9 UPF0379 protein ybiM H5C80_20250 ENOG4105KSC Transcriptional regulator, TraR DksA family H5C80_20255 ENOG4105VR4 UPF0379 protein ybiJ H5C80_20260 ENOG4105DG4 malate L-lactate dehydrogenase H5C80_20265 ENOG4108MTB glycosyl transferase family H5C80_20270 ENOG4105DVT helicase H5C80_20280 ENOG4105C1J atp-dependent rna helicase H5C80_20285 ENOG4107MVR Transcriptional regulator H5C80_20295 ENOG4105CJ1 ABC, transporter H5C80_20300 ENOG4107QWP ABC-2 type transporter H5C80_20305 ENOG4107QWP ABC-2 type transporter H5C80_20310 ENOG4105I9U inner membrane protein ybhQ H5C80_20315 ENOG4105X23 Endonuclease Exonuclease phosphatase H5C80_20320 ENOG4105DZQ phospholipase D Transphosphatidylase H5C80_20325 ENOG4107UXM Membrane H5C80_20330 ENOG410733J conserved inner membrane protein H5C80_20335 ENOG4105HFZ Membrane H5C80_20340 ENOG4108ZAF Molybdopterin H5C80_20345 ENOG4105M00 molybdopterin converting factor, subunit 1 H5C80_20355 ENOG4108RIR Molybdenum cofactor biosynthesis protein H5C80_20365 ENOG4105CHW UPF0052 protein H5C80_20375 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) H5C80_20380 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) H5C80_20395 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) H5C80_20400 ENOG4108V1U phospholipid-binding protein H5C80_20420 ENOG4108NKV transcriptional regulator H5C80_20425 ENOG4105UZW Tail fiber assembly protein H5C80_20430 ENOG4108X9F tail fiber protein H5C80_20505 ENOG4105IM0 capsid protein H5C80_20515 ENOG4105F7J membrane-bound serine protease H5C80_20525 ENOG4107DE1 head-to-tail joining protein H5C80_20530 ENOG4105UZW Tail fiber assembly protein H5C80_20535 ENOG4105FKG DNA packaging protein H5C80_20540 ENOG4106YSC H5C80_20545 ENOG41064WM Uncharacterized protein YcgX H5C80_20555 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 H5C80_20560 ENOG4105KUS lysozyme H5C80_20565 ENOG4105QFS Lysis protein S homolog from lambdoid prophage H5C80_20570 ENOG4108MIW Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions H5C80_20575 ENOG4107SEY Conserved Protein H5C80_20585 ENOG4105HRS Antitermination protein H5C80_20615 ENOG4105NY2 NinB protein H5C80_20735 ENOG4108I1J Integrase H5C80_20740 ENOG4105NBR Pectinesterase H5C80_20745 ENOG4107QM5 aconitate hydratase H5C80_20750 ENOG4107QPK )-transporter H5C80_20755 ENOG4105C7F AcnD-accessory protein PrpF H5C80_20760 ENOG4105F04 LysR family Transcriptional regulator H5C80_20770 ENOG4108K4B hydrolase H5C80_20775 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) H5C80_20780 ENOG4105E0C molybdate abc transporter H5C80_20785 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein H5C80_20795 ENOG4105F4R Transcriptional regulator mode H5C80_20800 ENOG4105DKW ABC transporter H5C80_20805 ENOG4105CMR udp-glucose 4-epimerase H5C80_20810 ENOG4105F0Z galactose-1-phosphate uridylyltransferase H5C80_20820 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) H5C80_20830 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) H5C80_20835 ENOG4105JND homeobox protein H5C80_20840 ENOG4105PGM cation diffusion facilitator family transporter H5C80_20845 ENOG4106Z1T Nicotinamide Mononucleotide Transporter H5C80_20850 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) H5C80_20890 ENOG4105UFD tol-pal system protein YbgF H5C80_20895 ENOG4105KCK Peptidoglycan-associated lipoprotein H5C80_20905 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA H5C80_20915 ENOG4105E02 MotA TolQ exbB proton channel H5C80_20920 ENOG4107YD3 Thioesterase H5C80_20925 ENOG4105KJB cyd operon protein YbgE H5C80_20935 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii H5C80_20940 ENOG4105C4M (Ubiquinol oxidase) subunit I H5C80_20950 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha H5C80_20960 ENOG4105C7S Dehydrogenase H5C80_20965 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 H5C80_20970 ENOG4105E33 succinate dehydrogenase H5C80_20975 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) H5C80_20980 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein H5C80_20985 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit H5C80_20995 ENOG4105BZN citrate synthase H5C80_21000 ENOG4106UBK fimbrial-like adhesin protein H5C80_21005 ENOG4106PG1 outer membrane usher protein H5C80_21010 ENOG4108TTM chaperone H5C80_21015 ENOG4108MY7 Fimbrial H5C80_21020 ENOG4108KK1 membrane protein AbrB duplication H5C80_21025 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) H5C80_21035 ENOG4107R7A Allophanate hydrolase subunit 2 H5C80_21040 ENOG4105P4J Allophanate hydrolase, subunit 1 H5C80_21045 ENOG4107QNR UPF0135 protein H5C80_21050 ENOG4105DUX Transporter H5C80_21055 ENOG4105CVP deoxyribo-dipyrimidine photolyase H5C80_21060 ENOG4107SEY Conserved Protein H5C80_21085 ENOG410600T transposase H5C80_21100 ENOG4105CNA YD repeat protein H5C80_21120 ENOG4105CNA YD repeat protein H5C80_21125 ENOG4105F5W AtP-binding protein H5C80_21130 ENOG4105D70 Integrase catalytic subunit H5C80_21155 ENOG4105XIQ Protein of unknown function (DUF2517) H5C80_21175 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) H5C80_21180 ENOG4105C08 Histidine kinase H5C80_21185 ENOG4105EEX Two component transcriptional regulator (Winged helix family H5C80_21195 ENOG4105CXN decarboxylase H5C80_21200 ENOG4105D5Q Arginine ornithine antiporter H5C80_21215 ENOG4108RS6 transposase H5C80_21220 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 H5C80_21225 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) H5C80_21230 ENOG4105EV9 Alpha Beta Hydrolase H5C80_21235 ENOG4105NNH LexA regulated protein H5C80_21240 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) H5C80_21250 ENOG41090R7 Ferric uptake H5C80_21255 ENOG4105GX6 (LipO)protein H5C80_21275 ENOG4105CI1 PTS System H5C80_21285 ENOG4105CE4 GlcNAc 6-P deacetylase H5C80_21290 ENOG4105E2R ROK family H5C80_21295 ENOG4105D4U had-superfamily hydrolase, subfamily iia H5C80_21300 ENOG4105CAQ asparagine synthetase H5C80_21345 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family H5C80_21355 ENOG4105C9A Phoh family H5C80_21365 ENOG4108JU5 Magnesium and cobalt efflux protein H5C80_21370 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) H5C80_21375 ENOG4107U91 Rhomboid family H5C80_21380 ENOG4107RP9 extracellular solute-binding protein, family 3 H5C80_21385 ENOG4105EAD ABC transporter H5C80_21390 ENOG4105DRP amino acid AbC transporter H5C80_21395 ENOG4105CDA abc transporter atp-binding protein H5C80_21405 ENOG4107PAI alpha helical protein H5C80_21420 ENOG4105DJF DNA polymerase III, delta' subunit H5C80_21435 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) H5C80_21445 ENOG4105CJN penicillin-binding protein H5C80_21450 ENOG4105CNI cell division protein FtsW H5C80_21455 ENOG4105K6T rare lipoprotein A H5C80_21460 ENOG4105DZ1 carboxypeptidase H5C80_21475 ENOG41064T2 transcriptional regulator, lysR family H5C80_21485 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) H5C80_21505 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) H5C80_21510 ENOG4105CEE C4-dicarboxylate transporter H5C80_21515 ENOG4106YYS transcriptional regulatory protein H5C80_21520 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism H5C80_21525 ENOG4105DUA (citrate (pro-3S)-lyase ligase H5C80_21535 ENOG4105CI0 Citrate lyase H5C80_21540 ENOG4105CHY citrate lyase, alpha H5C80_21555 ENOG4107QPK )-transporter H5C80_21560 ENOG4105KTS ribonuclease H5C80_21565 ENOG4105NXH GreA GreB family elongation factor H5C80_21570 ENOG4108U51 Universal stress protein H5C80_21575 ENOG4108JU3 Alkyl hydroperoxide reductase H5C80_21580 ENOG4105D3R alkyl hydroperoxide reductase H5C80_21585 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase H5C80_21590 ENOG4105DQS Transcriptional regulator H5C80_21595 ENOG4105BZV Phosphoadenosine phosphosulfate reductase H5C80_21600 ENOG4105GTN ParB Domain Protein Nuclease H5C80_21605 ENOG4105CHM Aminotransferase H5C80_21610 ENOG4107SCQ Iron-containing alcohol dehydrogenase H5C80_21615 ENOG4105VCD cytoplasmic protein H5C80_21620 ENOG4105D22 carbon starvation protein H5C80_21625 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) H5C80_21630 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase H5C80_21635 ENOG4105WQI isochorismatase H5C80_21640 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase H5C80_21645 ENOG4105E4F Isochorismate synthase H5C80_21650 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein H5C80_21660 ENOG4105DQ5 transport system permease protein H5C80_21665 ENOG4105TVJ transport system, permease H5C80_21670 ENOG4105E0A ABC, transporter H5C80_21675 ENOG4108QY5 Ferric enterobactin transport protein H5C80_21680 ENOG4105C0W non-ribosomal peptide synthetase H5C80_21685 ENOG41085A6 mbth domain-containing protein H5C80_21690 ENOG4105E93 esterase H5C80_21695 ENOG4107RNH Outer membrane receptor FepA H5C80_21700 ENOG4108TSE Transferase H5C80_21705 ENOG4108SER Transposase H5C80_21715 ENOG4108SER Transposase H5C80_21725 ENOG4108SER Transposase H5C80_21740 ENOG4105WQ6 Membrane H5C80_21745 ENOG4105MSB protein, conserved in bacteria H5C80_21750 ENOG4108RCM Nitroreductase H5C80_21755 ENOG4105CUY Mechanosensitive ion channel H5C80_21760 ENOG4105C85 amino acid H5C80_21765 ENOG4108IJF Heavy metal efflux pump, CzcA H5C80_21770 ENOG4105EP1 Efflux transporter rnd family, mfp subunit H5C80_21775 ENOG410624V efflux system protein H5C80_21780 ENOG4105ENJ RND efflux system, outer membrane lipoprotein H5C80_21785 ENOG4105CK6 Two component transcriptional regulator (Winged helix family H5C80_21790 ENOG4105GR3 Histidine kinase H5C80_21795 ENOG410802X bacteriophage n4 adsorption protein b H5C80_21805 ENOG4105QUW H5C80_21810 ENOG4108NC2 Outer membrane protease H5C80_21815 ENOG4108WF3 methyltransferase H5C80_21840 ENOG4105WQ3 Rna-binding protein H5C80_21845 ENOG4105S2T inner membrane protein YbcI H5C80_21855 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) H5C80_21865 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) H5C80_21870 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit H5C80_21875 ENOG4105C5B carbamate kinase H5C80_21880 ENOG4105G5A Protein of unknown function (DUF2877) H5C80_21885 ENOG4107REC cytoplasmic protein H5C80_21890 ENOG4107R1Q Membrane protein FdrA H5C80_21895 ENOG4105DG4 malate L-lactate dehydrogenase H5C80_21900 ENOG4105CE7 Amidase, hydantoinase carbamoylase family H5C80_21905 ENOG4105S0E allantoin catabolism protein H5C80_21910 ENOG4105BZW Glycerate kinase H5C80_21915 ENOG4105DTE Xanthine uracil vitamin C permease H5C80_21925 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease H5C80_21930 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase H5C80_21935 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) H5C80_21940 ENOG41060W2 glyoxylate carboligase H5C80_21945 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region H5C80_21955 ENOG4107653 Transcriptional regulator H5C80_21965 ENOG4105CV6 ABC transporter, permease H5C80_21970 ENOG4108I0Y (ABC) transporter H5C80_21975 ENOG4108UJV acyl-CoA thioesterase i H5C80_21980 ENOG4105E1F short-chain dehydrogenase reductase H5C80_21985 ENOG4107QR8 Thioredoxin H5C80_21990 ENOG4105C4B ABC transporter, permease H5C80_21995 ENOG41083J0 (ABC) transporter H5C80_22000 ENOG4107QX8 SPFH domain, Band 7 family protein H5C80_22005 ENOG4105G5H Membrane H5C80_22030 ENOG4108Z6Z Transcriptional regulator H5C80_22035 ENOG4107RY6 amino acid H5C80_22040 ENOG4105CSV Glutaminase H5C80_22045 ENOG4105C59 p-type ATPase H5C80_22050 ENOG41081XE plasmid maintenance system antidote protein, xre family H5C80_22055 ENOG41080ET plasmid maintenance system killer protein H5C80_22060 ENOG4105MBR gumn family H5C80_22065 ENOG4108Z66 YbaK ebsC protein H5C80_22070 ENOG4105CGH 5'-nucleotidase H5C80_22075 ENOG4105EU0 Major facilitator Superfamily H5C80_22080 ENOG4105CKD glutathione-regulated potassium-efflux system protein H5C80_22085 ENOG4107RE1 Inosine-guanosine kinase H5C80_22120 ENOG4107QMP dna polymerase iii subunits gamma and tau H5C80_22130 ENOG4105WD1 Membrane H5C80_22135 ENOG4108URS primosomal replication protein n'' H5C80_22140 ENOG4106428 Protein of unknown function (DUF2496) H5C80_22145 ENOG4105EGS Mechanosensitive ion channel H5C80_22150 ENOG4107XI7 Tetr family transcriptional regulator H5C80_22155 ENOG4105C1P efflux transporter, rnd family, mfp subunit H5C80_22160 ENOG4105BZS acriflavin resistance protein H5C80_22165 ENOG4108UKR Biofilm formation regulator YbaJ H5C80_22170 ENOG4105KF5 hemolysin expression-modulating protein H5C80_22175 ENOG4108UW5 maltose o-acetyltransferase H5C80_22180 ENOG4105GSJ Inner membrane protein ylaC H5C80_22185 ENOG41066DG (EAL) domain protein H5C80_22190 ENOG4105KCV RNA signal recognition particle 4.5S RNA H5C80_22200 ENOG41080UX Methyltransferase H5C80_22205 ENOG4108MNP Glycoprotein polysaccharide metabolism H5C80_22210 ENOG4105C29 acyl-CoA thioesterase H5C80_22215 ENOG4105BZU Histidine kinase H5C80_22220 ENOG4108YZA Nitrogen regulatory protein pii H5C80_22225 ENOG4105BZ1 (ABC) transporter H5C80_22230 ENOG4105BZ1 (ABC) transporter H5C80_22235 ENOG4108XM1 transcriptional regulator AsnC family H5C80_22245 ENOG4108NFA extracellular solute-binding protein H5C80_22255 ENOG4108TGP Thioesterase superfamily protein H5C80_22260 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein H5C80_22265 ENOG4105EIN peptidylprolyl cis-trans isomerase H5C80_22270 ENOG4105K70 DNA-binding protein H5C80_22275 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) H5C80_22295 ENOG4105M85 Bola protein H5C80_22300 ENOG4105IEY (LipO)protein H5C80_22305 ENOG4105EYM Major Facilitator superfamily H5C80_22310 ENOG4105E2S oxidase) subunit II H5C80_22315 ENOG4105BZ9 Cytochrome C oxidase, subunit I H5C80_22320 ENOG4105CCU oxidase (Subunit III) H5C80_22325 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) H5C80_22335 ENOG4107RDB Major Facilitator H5C80_22345 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) H5C80_22350 ENOG4107S0N DJ-1 family H5C80_22355 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) H5C80_22365 ENOG4105CTB Polyprenyl synthetase H5C80_22375 ENOG4105CPC Aldo Keto reductase H5C80_22380 ENOG4108ZAI phosphatidylglycerophosphatase a H5C80_22385 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) H5C80_22395 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) H5C80_22400 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) H5C80_22410 ENOG4108KIC (LipO)protein H5C80_22415 ENOG4105DRB nucleoside-specific channel-forming protein H5C80_22420 ENOG4105N1F Hnh endonuclease H5C80_22425 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) H5C80_22430 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) H5C80_22435 ENOG4105VIE preprotein translocase, subunit YajC H5C80_22455 ENOG4107R28 alpha amylase, catalytic region H5C80_22460 ENOG4105C85 amino acid H5C80_22465 ENOG4105CWM branched-chain amino acid transport system II carrier protein H5C80_22470 ENOG4105BZU Histidine kinase H5C80_22475 ENOG4105CK6 Two component transcriptional regulator (Winged helix family H5C80_22480 ENOG4107RH8 nuclease SbcCD subunit D H5C80_22485 ENOG4105EYH Exonuclease H5C80_22490 ENOG4105F27 Major Facilitator H5C80_22495 ENOG4105DKQ ROK family H5C80_22520 ENOG4105HBA AroM protein H5C80_22525 ENOG4105SS3 H5C80_22540 ENOG4105II7 pyrroline-5-carboxylate reductase H5C80_22545 ENOG4105BZU Histidine kinase H5C80_22550 ENOG4105VIF phosphate starvation-inducible protein H5C80_22555 ENOG4105G6Z alkaline phosphatase H5C80_22570 ENOG4105CPF Cell wall formation (By similarity) H5C80_22575 ENOG4105UNH Membrane H5C80_22580 ENOG4105FR5 inner membrane protein YaiY H5C80_22585 ENOG4107QS8 (LipO)protein H5C80_22590 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 H5C80_22595 ENOG4107R6D beta-lactam binding protein AmpH H5C80_22600 ENOG4108PNB DNA-binding transcriptional regulator H5C80_22610 ENOG4105D52 delta-aminolevulinic acid dehydratase H5C80_22615 ENOG4105E2B Taurine dioxygenase H5C80_22620 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component H5C80_22625 ENOG4108IY8 ABC, transporter H5C80_22630 ENOG4106FTQ Taurine ABC transporter, periplasmic H5C80_22635 ENOG4107W19 lmbE family H5C80_22640 ENOG4108PBI Polysaccharide metabolism H5C80_22650 ENOG4105SRB Uncharacterized protein yaiO H5C80_22670 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme H5C80_22675 ENOG4108SC4 )-transporter H5C80_22710 ENOG4108K2P TRANSCRIPTIONal H5C80_22715 ENOG4105ETE Transcriptional regulator (LacI family H5C80_22725 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) H5C80_22730 ENOG4108UW5 maltose o-acetyltransferase H5C80_22735 ENOG4105DJ2 Major Facilitator Superfamily H5C80_22745 ENOG4107B2H carbonic anhydrase H5C80_22750 ENOG4105DND Transcriptional regulator H5C80_22755 ENOG4105DZC cytosine deaminase H5C80_22760 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin H5C80_22765 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) H5C80_22770 ENOG4105DXD 2-methylcitrate dehydratase H5C80_22775 ENOG4105BZN citrate synthase H5C80_22780 ENOG4105CR4 methylisocitrate lyase H5C80_22785 ENOG4108JU7 Transcriptional regulator H5C80_22790 ENOG4105TDT uncharacterized protein yahO H5C80_22795 ENOG4105E82 cytochrome subunit of dehydrogenase H5C80_22805 ENOG4105DQ4 alcohol dehydrogenase H5C80_22810 ENOG4105CNN ABC, transporter H5C80_22815 ENOG4105CNN ABC, transporter H5C80_22820 ENOG4105C2J ABC transporter H5C80_22825 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator H5C80_22835 ENOG4105DZC cytosine deaminase H5C80_22840 ENOG4105C5B carbamate kinase H5C80_22850 ENOG4107REC cytoplasmic protein H5C80_22855 ENOG4107R1Q Membrane protein FdrA H5C80_22860 ENOG4105N16 Protein of unknown function (DUF2877) H5C80_22865 ENOG4107SNB ankyrin repeat protein YahD H5C80_22870 ENOG4105SZ2 membrAne H5C80_22875 ENOG4108NUU Transcriptional regulator H5C80_22880 ENOG4105BZU Histidine kinase H5C80_22910 ENOG4108W9T type 1 fimbriae regulatory protein H5C80_22915 ENOG4105BZU Histidine kinase H5C80_22940 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) H5C80_22945 ENOG4107QR9 Iron-sulfur cluster binding protein H5C80_22950 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) H5C80_22955 ENOG4108K01 transcriptional regulator H5C80_22960 ENOG4107QN2 dihydrolipoyl dehydrogenase H5C80_22965 ENOG41066GK UPF0379 protein ykgI H5C80_22970 ENOG4108KBJ Inner membrane protein YkgB H5C80_22975 ENOG4105CV8 reductase H5C80_22995 ENOG4107SET aldo keto reductase H5C80_23000 ENOG4105EQ2 LysR family Transcriptional regulator H5C80_23050 ENOG4106PYX Receptor H5C80_23060 ENOG4105PI0 Ferredoxin H5C80_23065 ENOG4105R3P Inner membrane protein yagU H5C80_23110 ENOG4105FCK Membrane H5C80_23115 ENOG4108UVK Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity) H5C80_23120 ENOG4105V1F Fermentation respiration switch protein H5C80_23130 ENOG4105CIN aminoacyl-histidine dipeptidase H5C80_23135 ENOG4108S2Y peptide Chain Release factor H5C80_23145 ENOG4108HYG acetyltransferase H5C80_23150 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) H5C80_23165 ENOG4108YS0 lipoprotein YafL H5C80_23170 ENOG4105F7V ErfK ybiS ycfS ynhG family protein H5C80_23175 ENOG4105E7A Glutamine amidotransferase H5C80_23185 ENOG4107QPN acyl-Coa dehydrogenase H5C80_23190 ENOG4108WN0 inhibitor of vertebrate lysozyme H5C80_23195 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase H5C80_23310 ENOG4108F1U ABC transporter H5C80_23315 ENOG4105EHG Permease protein H5C80_23340 ENOG4108EU4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) H5C80_23365 ENOG4108F5E vimentin H5C80_23370 ENOG4108YIV H5C80_23400 ENOG4106H6R UPF0380 protein H5C80_23410 ENOG4105MFG Antirestriction protein H5C80_23415 ENOG4108YGG dna repair protein H5C80_23430 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles H5C80_23455 ENOG4108YXQ IS66 Orf2 family protein H5C80_23475 ENOG4107RZZ dna polymerase iii epsilon subunit H5C80_23485 ENOG4105D1A Methyltransferase H5C80_23490 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) H5C80_23495 ENOG4105E9H Lytic Murein transglycosylase H5C80_23500 ENOG4105F2W methyltransferase H5C80_23510 ENOG4105HEI LysR family (Transcriptional regulator H5C80_23515 ENOG4105CV8 reductase H5C80_23550 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase H5C80_23555 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) H5C80_23560 ENOG4108UMI ABC transporter, permease H5C80_23565 ENOG4105D01 (LipO)protein H5C80_23570 ENOG4108R8X outer membrane lipoprotein H5C80_23575 ENOG4108R96 Methyltransferase, YaeB family H5C80_23585 ENOG4108UY0 (LipO)protein H5C80_23590 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion H5C80_23595 ENOG4108YZN class I peptide chain release factor H5C80_23600 ENOG4108VWS Yaeq family H5C80_23610 ENOG4105M1T rho-binding antiterminator H5C80_23615 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) H5C80_23620 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase H5C80_23625 ENOG4105CXN decarboxylase H5C80_23635 ENOG4105C0B DNA polymerase III (alpha subunit) H5C80_23660 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) H5C80_23665 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) H5C80_23675 ENOG4105DZP Membrane-associated zinc metalloprotease H5C80_23680 ENOG4105KNE Phosphatidate cytidylyltransferase H5C80_23685 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) H5C80_23690 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) H5C80_23715 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) H5C80_23730 ENOG4105DIN metallophosphoesterase H5C80_23740 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR H5C80_23745 ENOG4105C0H protease H5C80_23760 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) H5C80_23765 ENOG4105EN6 Membrane H5C80_23790 ENOG4105S6R Iron-hydroxamate transporter permease subunit H5C80_23795 ENOG4105J76 Periplasmic binding protein H5C80_23800 ENOG4105E0A ABC, transporter H5C80_23805 ENOG4105E0K tonB-dependent siderophore receptor H5C80_23810 ENOG4105BZ4 penicillin-binding protein H5C80_23815 ENOG4105CQ7 ATP-dependent helicase H5C80_23820 ENOG4107XID 2'-5' rna ligase H5C80_23835 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) H5C80_23840 ENOG4105DJ0 Poly(A) Polymerase H5C80_23845 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase H5C80_23855 ENOG4108VEV chaperone H5C80_23860 ENOG4105CW0 outer membrane usher protein H5C80_23865 ENOG4108XEY fimbrial-like adhesin protein H5C80_23870 ENOG4105SYG Fimbrial protein H5C80_23875 ENOG4105SN2 fimbrial-like adhesin protein H5C80_23880 ENOG4105P0Q fimbrial-like protein YadC H5C80_23890 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) H5C80_23895 ENOG4108A32 Transposase H5C80_23905 ENOG4107BJW polysaccharide deacetylase H5C80_23910 ENOG4108YTN IIa component H5C80_23915 ENOG4105E3A (ABC) transporter H5C80_23920 ENOG4105DA5 (ABC) transporter H5C80_23925 ENOG41077A9 carbonic anhydrase H5C80_23930 ENOG4108UGV hypoxanthine phosphoribosyltransferase H5C80_23935 ENOG4105DZG Dehydrogenase H5C80_23940 ENOG4105E3B Multicopper oxidase H5C80_23945 ENOG4108ZRK uncharacterized protein yacC H5C80_23965 ENOG4107QIJ Aconitate hydratase 2 H5C80_23970 ENOG4108NST exported protein H5C80_23975 ENOG4107QN2 dihydrolipoyl dehydrogenase H5C80_23980 ENOG4107QSN dihydrolipoamide acetyltransferase H5C80_23985 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) H5C80_23990 ENOG41073TP transcriptional regulator H5C80_23995 ENOG4105C85 amino acid H5C80_24000 ENOG4106A72 regulatory protein AmpE H5C80_24005 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase H5C80_24010 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase H5C80_24015 ENOG4108ZUW Major pilin subunit H5C80_24020 ENOG4107QHF type ii secretion system protein e H5C80_24025 ENOG4105D7Q type ii secretion system H5C80_24040 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) H5C80_24055 ENOG4105M6F mutator MutT protein H5C80_24075 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) H5C80_24080 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) H5C80_24085 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) H5C80_24090 ENOG4105CPF Cell wall formation (By similarity) H5C80_24105 ENOG4105CNI cell division protein FtsW H5C80_24110 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) H5C80_24120 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) H5C80_24125 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) H5C80_24130 ENOG4105CJN penicillin-binding protein H5C80_24135 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) H5C80_24150 ENOG4107B7Y DNA-binding transcriptional regulator FruR H5C80_24160 ENOG4108ZP8 Acetolactate synthase small subunit H5C80_24165 ENOG4105C7K acetolactate synthase H5C80_24175 ENOG41064T2 transcriptional regulator, lysR family H5C80_24190 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) H5C80_24215 ENOG4105DP9 ABC transporter H5C80_24220 ENOG4106SMU thiamine transporter membrane protein H5C80_24230 ENOG4108KF1 Membrane H5C80_24235 ENOG41063TF transcriptional regulator (AraC H5C80_24250 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase H5C80_24255 ENOG4105CQ2 DNA polymerase H5C80_24265 ENOG4105D3G Pseudouridine synthase H5C80_24270 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) H5C80_24275 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) H5C80_24280 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) H5C80_24320 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) H5C80_24335 ENOG4105C54 Major Facilitator superfamily H5C80_24340 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein H5C80_24345 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase H5C80_24375 ENOG4105CEY Amp-dependent synthetase and ligase H5C80_24380 ENOG4106YT9 Enoyl-CoA hydratase H5C80_24390 ENOG4108XNW Transcriptional activatory protein CaiF H5C80_24395 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain H5C80_24400 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain H5C80_24420 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase H5C80_24435 ENOG4105DTN riboflavin biosynthesis protein ribF H5C80_24440 ENOG410647N response to DNA damage stimulus H5C80_24450 ENOG41063Z6 transcriptional regulator, lysR family H5C80_24460 ENOG4105WI6 cell killing protein encoded within cryptic prophage H5C80_24480 ENOG4108QUJ UPF0174 protein YaaW H5C80_24485 ENOG4106HK8 GPR1 FUN34 yaaH family protein H5C80_24490 ENOG4108RIR Molybdenum cofactor biosynthesis protein H5C80_24500 ENOG4105BZG amino acid carrier protein H5C80_24510 ENOG41062C6 Protein of unknown function (DUF2502) H5C80_24515 ENOG4105D98 threonine synthase H5C80_24525 ENOG4105CFH Aspartokinase H5C80_24535 ENOG4106FVC RNA methyltransferase H5C80_24540 ENOG410759A H5C80_24545 ENOG41065U4 response regulator H5C80_24550 ENOG4105CT7 inner membrane cred family protein H5C80_24555 ENOG4105EB3 Histidine kinase H5C80_24560 ENOG4105E3W Two component transcriptional regulator (Winged helix family H5C80_24565 ENOG4108RH0 Crea protein H5C80_24570 ENOG4105UEI Transcriptional Regulator AraC Family H5C80_24580 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) H5C80_24590 ENOG4107SC1 transglycosylase H5C80_24595 ENOG4105C5H ABC transporter H5C80_24605 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system H5C80_24610 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase H5C80_24615 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) H5C80_24620 ENOG4105EAC phosphoserine phosphatase H5C80_24625 ENOG41062Z9 Membrane H5C80_24640 ENOG4105D3A purine nucleoside phosphorylase DeoD-type H5C80_24660 ENOG4105G0K glycine radical enzyme YjjI family H5C80_24665 ENOG41076CZ activating enzyme H5C80_24670 ENOG4105EYA deoxyribonuclease H5C80_24675 ENOG4108NRW Phospholipase, patatin family H5C80_24685 ENOG4105K3G Periplasmic Protein H5C80_24695 ENOG4105PAD Hydrolase H5C80_24700 ENOG4105KEG ribosomal-protein-alanine acetyltransferase H5C80_24705 ENOG4108WPU DNA polymerase III subunit psi H5C80_24710 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) H5C80_24730 ENOG4105YBH Protein of unknown function (DUF1435) H5C80_24735 ENOG4108819 ferric iron reductase H5C80_24740 ENOG4108T94 DNA-binding transcriptional activator BglJ H5C80_24745 ENOG4108N8T regulatoR H5C80_24750 ENOG4105DWK Membrane H5C80_24765 ENOG4106CVF DNA replication protein H5C80_24770 ENOG4105RI1 glycoprotein receptor H5C80_24775 ENOG4107RES phosphoglycerol transferase I H5C80_24780 ENOG4105CPQ Dehydrogenase H5C80_24785 ENOG410617M Transcriptional regulator H5C80_24790 ENOG4108I5G Major Facilitator superfamily H5C80_24795 ENOG4108I5G Major Facilitator superfamily H5C80_24800 ENOG4105C8Q Methyl-accepting chemotaxis H5C80_24810 ENOG4108IA2 Sodium pantothenate symporter H5C80_24830 ENOG4105D22 carbon starvation protein H5C80_24835 ENOG4105VCD cytoplasmic protein H5C80_24840 ENOG4105CKI cobalamin synthesis protein H5C80_24855 ENOG4106H3A restriction H5C80_24860 ENOG4105CVR type I restriction-modification system H5C80_24870 ENOG4105DZR Type I site-specific deoxyribonuclease H5C80_24880 ENOG4106DIZ Domain of unknown function (DUF1127) H5C80_24885 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family H5C80_24900 ENOG41083G8 Multidrug resistance protein MdtM H5C80_24905 ENOG4106BRA Membrane H5C80_24910 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase H5C80_24915 ENOG4105CIZ coA-substrate-specific enzyme activase H5C80_24930 ENOG4105CBP Major Facilitator H5C80_24940 ENOG41074DU domain protein H5C80_24945 ENOG4108P2H Inner membrane protein YjiG H5C80_24950 ENOG4105DYB Isoaspartyl dipeptidase H5C80_24955 ENOG4107YNJ LysR family Transcriptional regulator H5C80_24970 ENOG4105C6F GntR Family Transcriptional Regulator H5C80_24975 ENOG4105DEI Mannitol dehydrogenase H5C80_24985 ENOG4107EFN gluconate transport system permease 3 H5C80_24990 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin H5C80_24995 ENOG4108T65 Fimbrial H5C80_25000 ENOG4108SQA Fimbrial H5C80_25005 ENOG4105CW0 outer membrane usher protein H5C80_25010 ENOG4108NAE Fimbrial chaperone protein H5C80_25015 ENOG4108S54 Fimbrial protein H5C80_25025 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off H5C80_25030 ENOG4108W9T type 1 fimbriae regulatory protein H5C80_25035 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria H5C80_25090 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles H5C80_25100 ENOG4108YGG dna repair protein H5C80_25105 ENOG4106549 Antirestriction protein H5C80_25115 ENOG4106H6R UPF0380 protein H5C80_25130 ENOG4108KZE transcriptional regulator H5C80_25135 ENOG4105TS0 gtp-binding protein H5C80_25165 ENOG4108NC2 Outer membrane protease H5C80_25180 ENOG4105DJY efflux transporter, rnd family, mfp subunit H5C80_25190 ENOG4105ENJ RND efflux system, outer membrane lipoprotein H5C80_25230 ENOG4105QYK bacteriophage lambda Bor protein homolog H5C80_25255 ENOG4105E93 esterase H5C80_25260 ENOG4105NIV Esterase H5C80_25265 ENOG4107RNH Outer membrane receptor FepA H5C80_25285 ENOG4105D70 Integrase catalytic subunit H5C80_25290 ENOG4105F5W AtP-binding protein H5C80_25300 ENOG4108MBX Secretion Protein H5C80_25330 ENOG4105H3G oxidoreductase H5C80_25340 ENOG4108YXQ IS66 Orf2 family protein H5C80_25410 ENOG4105MN3 Resolvase H5C80_25425 ENOG4105EHG Permease protein H5C80_25430 ENOG4105E0A ABC, transporter H5C80_25480 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) H5C80_25490 ENOG4107R1Q Membrane protein FdrA H5C80_25495 ENOG4107REC cytoplasmic protein H5C80_25500 ENOG4105C5B carbamate kinase H5C80_25510 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin H5C80_25515 ENOG4105F52 Transcriptional regulator H5C80_25560 ENOG4108NUU Transcriptional regulator H5C80_25565 ENOG4107SNB ankyrin repeat protein YahD H5C80_25570 ENOG4105N16 Protein of unknown function (DUF2877) H5C80_25575 ENOG4107R1Q Membrane protein FdrA H5C80_25580 ENOG4107REC cytoplasmic protein H5C80_25590 ENOG4105C5B carbamate kinase H5C80_25630 ENOG4106CQM replication H5C80_25665 ENOG4107CBI conjugal transfer fertility inhibition protein H5C80_25670 ENOG4107U2T alpha beta H5C80_25685 ENOG4105VGJ Virulence-associated protein H5C80_25690 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A H5C80_25950 ENOG4106JQ7 H5C80_25955 ENOG41073YN Protein of unknown function (DUF1380) H5C80_26020 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) H5C80_26025 ENOG4105DUU IucA IucC family protein H5C80_26045 ENOG41082CG Protein CrcB homolog H5C80_26060 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase H5C80_26075 ENOG4105CC5 ABC transporter H5C80_26080 ENOG4105CC5 ABC transporter H5C80_26085 ENOG4105DIK (ABC) transporter H5C80_26240 ENOG4108BUD transposase H5C80_26385 ENOG410607W Transposase H5C80_26440 ENOG41073YN Protein of unknown function (DUF1380) H5C80_26475 ENOG4105EKQ RNA-directed DNA polymerase H5C80_26590 ENOG4105E5H Transposase H5C80_26595 ENOG4108YXQ IS66 Orf2 family protein H5C80_26700 ENOG4105CZX twitching motility protein H5C80_26760 ENOG4105K5T PilT protein H5C80_26775 ENOG4107QHF type ii secretion system protein e H5C80_26865 ENOG4108R1E Serine threonine protein phosphatase 1 H5C80_26925 ENOG4105CDU Replicative dna helicase H5C80_26960 ENOG4105DFE Dna adenine methylase H5C80_26965 ENOG4105DH7 May be involved in recombination (By similarity) H5C80_26990 ENOG4106JVB Replication Protein H5C80_27070 ENOG4108ZMA Outer membrane lipoprotein H5C80_27075 ENOG41066DY Membrane H5C80_27120 ENOG4108X9F tail fiber protein H5C80_27120 ENOG4108X9F tail fiber protein H5C80_27135 ENOG4105UZW Tail fiber assembly protein H5C80_27300 ENOG4105KT5 UmuD protein H5C80_27305 ENOG4105MPK DNA polymerase III subunit theta H5C80_27405 ENOG4105X1N Glycosyl transferase family 8 H5C80_27420 ENOG4105QFS Lysis protein S homolog from lambdoid prophage