locus-tag	class	description
H5C80_00075	COG1595	DNA-templated transcription, initiation
H5C80_00080	COG3712	iron ion homeostasis
H5C80_00085	COG4772	TonB-dependent receptor
H5C80_00090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H5C80_00095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_00100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_00105	COG1120	ATPase activity
H5C80_00110	COG2085	NADP oxidoreductase coenzyme F420-dependent
H5C80_00120	COG2826	transposase and inactivated derivatives, IS30 family
H5C80_00135	COG3436	PFAM IS66 Orf2 family protein
H5C80_00210	COG2200	EAL domain
H5C80_00225	COG0582	viral genome integration into host DNA
H5C80_00235	COG1064	alcohol dehydrogenase
H5C80_00240	COG0433	COG0433 Predicted ATPase
H5C80_00245	COG0795	lipopolysaccharide-transporting ATPase activity
H5C80_00250	COG0795	lipopolysaccharide-transporting ATPase activity
H5C80_00260	COG2927	DNA polymerase III (CHI subunit)
H5C80_00265	COG0525	valine-tRNA ligase activity
H5C80_00270	COG4269	membrane
H5C80_00275	COG0456	acetyltransferase
H5C80_00280	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
H5C80_00295	COG2731	YhcH YjgK YiaL family protein
H5C80_00300	COG1309	transcriptional regulator
H5C80_00305	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_00310	COG0251	oxidation-reduction process
H5C80_00330	COG0251	oxidation-reduction process
H5C80_00335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H5C80_00345	COG1609	Transcriptional regulator
H5C80_00350	COG1263	PTS System
H5C80_00350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_00355	COG0366	Alpha amylase catalytic
H5C80_00360	COG1328	CTP reductase activity
H5C80_00365	COG0602	queuosine metabolic process
H5C80_00370	COG3783	Cytochrome b(562)
H5C80_00375	COG0312	modulator of DNA gyrase
H5C80_00380	COG3028	Belongs to the UPF0307 family
H5C80_00385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H5C80_00395	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C80_00400	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C80_00405	COG1129	ABC transporter
H5C80_00410	COG1879	ABC-type sugar transport system periplasmic component
H5C80_00415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H5C80_00420	COG2105	PFAM AIG2 family protein
H5C80_00425	COG2911	Protein conserved in bacteria
H5C80_00430	COG0729	surface antigen
H5C80_00440	COG1253	flavin adenine dinucleotide binding
H5C80_00450	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H5C80_00460	COG1218	3'(2'),5'-bisphosphate nucleotidase
H5C80_00465	COG0737	Belongs to the 5'-nucleotidase family
H5C80_00470	COG1733	regulation of RNA biosynthetic process
H5C80_00475	COG0702	epimerase
H5C80_00480	COG0697	spore germination
H5C80_00500	COG1113	amino acid transport
H5C80_00505	COG0545	Peptidyl-prolyl cis-trans isomerase
H5C80_00510	COG3061	Opacity-associated protein A
H5C80_00515	COG1309	transcriptional regulator
H5C80_00530	COG1024	Enoyl-CoA hydratase
H5C80_00535	COG4670	ketone body catabolic process
H5C80_00540	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H5C80_00545	COG2271	Major facilitator Superfamily
H5C80_00565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H5C80_00605	COG3414	Phosphotransferase system galactitol-specific IIB component
H5C80_00610	COG3037	sugar-specific permease SgaT UlaA
H5C80_00625	COG1073	alpha beta
H5C80_00630	COG3650	response to hydrogen peroxide
H5C80_00640	COG1960	acyl-CoA dehydrogenase activity
H5C80_00645	COG0754	glutathionylspermidine amidase activity
H5C80_00650	COG5463	Belongs to the UPF0441 family
H5C80_00655	COG3766	membrane
H5C80_00665	COG1842	Phage shock protein A
H5C80_00670	COG3789	protein conserved in bacteria
H5C80_00675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H5C80_00680	COG0557	exoribonuclease II activity
H5C80_00695	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H5C80_00700	COG0330	HflC and HflK could
H5C80_00705	COG0330	HflC and HflK could
H5C80_00710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H5C80_00730	COG0860	N-Acetylmuramoyl-L-alanine amidase
H5C80_00735	COG0802	atpase or kinase
H5C80_00740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H5C80_00740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H5C80_00785	COG1511	domain protein
H5C80_00785	COG3264	Mechanosensitive ion channel
H5C80_00800	COG0531	amino acid
H5C80_00810	COG1053	succinate dehydrogenase
H5C80_00815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H5C80_00830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H5C80_00835	COG3040	lipid binding
H5C80_00840	COG2076	Multidrug Resistance protein
H5C80_00845	COG5510	response to toxic substance
H5C80_00850	COG5510	response to toxic substance
H5C80_00860	COG1509	lysine 2,3-aminomutase activity
H5C80_00885	COG0531	amino acid
H5C80_00890	COG3030	protein affecting phage T7 exclusion by the F plasmid
H5C80_00895	COG1027	Aspartate ammonia-lyase
H5C80_00900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H5C80_00910	COG4232	protein-disulfide reductase activity
H5C80_00915	COG1309	transcriptional regulator
H5C80_00925	COG3710	Transcriptional regulator
H5C80_00930	COG0531	amino acid
H5C80_00935	COG1982	Orn Lys Arg decarboxylase major
H5C80_00940	COG3104	oligopeptide transport
H5C80_00945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H5C80_00960	COG2388	GCN5-related N-acetyl-transferase
H5C80_00965	COG3592	Divergent 4Fe-4S mono-cluster
H5C80_00970	COG3290	protein histidine kinase activity
H5C80_00975	COG4565	transcriptional regulatory protein
H5C80_00980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H5C80_00985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C80_00985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C80_00990	COG3647	Membrane
H5C80_00995	COG2211	Major facilitator Superfamily
H5C80_01000	COG1486	melibiose metabolic process
H5C80_01005	COG2169	Transcriptional regulator
H5C80_01010	COG1982	Orn Lys Arg decarboxylase major
H5C80_01015	COG2207	Transcriptional regulator
H5C80_01020	COG0531	amino acid
H5C80_01025	COG2194	sulfuric ester hydrolase activity
H5C80_01030	COG0745	RESPONSE REGULATOR receiver
H5C80_01035	COG0642	Histidine kinase
H5C80_01045	COG0477	Major facilitator Superfamily
H5C80_01060	COG2824	Alkylphosphonate utilization operon protein PhnA
H5C80_01065	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H5C80_01075	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H5C80_01080	COG3639	organic phosphonate transmembrane transporter activity
H5C80_01085	COG2188	Transcriptional regulator
H5C80_01090	COG3624	Phosphonate C-P lyase system protein PhnG
H5C80_01095	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H5C80_01100	COG3626	phosphonate metabolism
H5C80_01105	COG3627	carbon phosphorus lyase activity
H5C80_01110	COG4107	phosphonate C-P lyase system protein PhnK
H5C80_01115	COG4778	phosphonate C-P lyase system protein PhnL
H5C80_01120	COG3454	Phosphonate metabolism
H5C80_01130	COG0456	acetyltransferase
H5C80_01135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H5C80_01145	COG0698	ribose 5-phosphate isomerase
H5C80_01150	COG1737	Transcriptional regulator
H5C80_01155	COG1879	ABC-type sugar transport system periplasmic component
H5C80_01160	COG1129	ABC transporter
H5C80_01165	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C80_01170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H5C80_01175	COG1940	carbohydrate kinase activity
H5C80_01180	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H5C80_01190	COG1566	PFAM secretion protein HlyD family protein
H5C80_01195	COG1289	transmembrane transporter activity
H5C80_01210	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H5C80_01215	COG1301	dicarboxylic acid transport
H5C80_01220	COG4235	cytochrome complex assembly
H5C80_01225	COG3088	subunit of a heme lyase
H5C80_01230	COG1138	Cytochrome C-type biogenesis protein
H5C80_01235	COG3301	Polysulphide reductase, NrfD
H5C80_01240	COG0437	4 iron, 4 sulfur cluster binding
H5C80_01245	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
H5C80_01255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H5C80_01260	COG3162	membrane
H5C80_01270	COG0025	NhaP-type Na H and K H
H5C80_01275	COG2252	PERMEase
H5C80_01280	COG0789	Transcriptional regulator
H5C80_01285	COG2207	Transcriptional regulator
H5C80_01290	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H5C80_01300	COG0629	single-stranded DNA binding
H5C80_01305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H5C80_01310	COG2315	Protein conserved in bacteria
H5C80_01315	COG0432	Pfam Uncharacterised protein family UPF0047
H5C80_01320	COG3700	Belongs to the class B bacterial acid phosphatase family
H5C80_01330	COG1448	Aminotransferase
H5C80_01335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H5C80_01340	COG0305	Participates in initiation and elongation during chromosome replication
H5C80_01345	COG0604	alcohol dehydrogenase
H5C80_01355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H5C80_01380	COG3778	Protein conserved in bacteria
H5C80_01385	COG3299	homolog of phage Mu protein gp47
H5C80_01405	COG4228	DNA circulation
H5C80_01430	COG4386	tail sheath protein
H5C80_01480	COG1802	Transcriptional regulator
H5C80_01480	COG4626	Terminase
H5C80_01505	COG3179	chitinase
H5C80_01525	COG0484	heat shock protein binding
H5C80_01530	COG1403	HNH endonuclease
H5C80_01540	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H5C80_01550	COG4725	Belongs to the MT-A70-like family
H5C80_01560	COG1846	Transcriptional regulator
H5C80_01610	COG5532	Uncharacterized conserved protein (DUF2303)
H5C80_01615	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H5C80_01655	COG0735	belongs to the Fur family
H5C80_01660	COG3237	CsbD-like
H5C80_01665	COG0534	Mate efflux family protein
H5C80_01675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H5C80_01705	COG3842	ATPase activity
H5C80_01710	COG2182	Extracellular solute-binding protein
H5C80_01715	COG1175	transmembrane transport
H5C80_01720	COG3833	ABC-type maltose transport systems, permease component
H5C80_01735	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C80_01760	COG0527	aspartate kinase activity
H5C80_01770	COG1187	pseudouridine synthase activity
H5C80_01815	COG1283	sodium-dependent phosphate transmembrane transporter activity
H5C80_01820	COG1410	methionine synthase
H5C80_01820	COG0646	methionine synthase
H5C80_01825	COG1414	Transcriptional regulator
H5C80_01835	COG2224	Isocitrate lyase
H5C80_01840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H5C80_01850	COG0456	acetyltransferase
H5C80_01880	COG0151	Belongs to the GarS family
H5C80_01885	COG2204	response regulator
H5C80_01890	COG4191	Histidine kinase
H5C80_01895	COG3678	ATP-independent chaperone mediated protein folding
H5C80_01910	COG3068	Protein conserved in bacteria
H5C80_01945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H5C80_01950	COG2104	thiamine diphosphate biosynthetic process
H5C80_01960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H5C80_01995	COG0250	Participates in transcription elongation, termination and antitermination
H5C80_02000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H5C80_02035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H5C80_02035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H5C80_02085	COG1309	transcriptional regulator
H5C80_02095	COG0583	DNA-binding transcription factor activity
H5C80_02100	COG2271	Major facilitator Superfamily
H5C80_02105	COG4948	Mandelate Racemase Muconate Lactonizing
H5C80_02120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H5C80_02135	COG2194	sulfuric ester hydrolase activity
H5C80_02140	COG2207	Transcriptional regulator
H5C80_02145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_02150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C80_02155	COG1882	Formate acetyltransferase
H5C80_02160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_02165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_02170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_02170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C80_02170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_02175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H5C80_02180	COG0371	Dehydrogenase
H5C80_02185	COG3738	Protein conserved in bacteria
H5C80_02190	COG0697	spore germination
H5C80_02200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H5C80_02205	COG0737	Belongs to the 5'-nucleotidase family
H5C80_02215	COG0737	Belongs to the 5'-nucleotidase family
H5C80_02220	COG0737	Belongs to the 5'-nucleotidase family
H5C80_02230	COG0460	homoserine dehydrogenase
H5C80_02230	COG0527	aspartate kinase activity
H5C80_02235	COG0626	cystathionine gamma-synthase activity
H5C80_02245	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H5C80_02255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H5C80_02260	COG1609	Transcriptional regulator
H5C80_02265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H5C80_02280	COG1575	Belongs to the MenA family. Type 1 subfamily
H5C80_02295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H5C80_02305	COG1494	fructose-1,6-bisphosphatase
H5C80_02315	COG0589	response to stress
H5C80_02320	COG3691	Protein conserved in bacteria
H5C80_02325	COG3152	Membrane
H5C80_02345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H5C80_02405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H5C80_02420	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C80_02515	COG4695	Portal protein
H5C80_02575	COG4974	Belongs to the 'phage' integrase family
H5C80_02580	COG3678	ATP-independent chaperone mediated protein folding
H5C80_02585	COG0745	RESPONSE REGULATOR receiver
H5C80_02590	COG2205	protein histidine kinase activity
H5C80_02595	COG2258	MOSC domain
H5C80_02605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H5C80_02630	COG4806	L-rhamnose isomerase
H5C80_02665	COG0437	4 iron, 4 sulfur cluster binding
H5C80_02670	COG2864	formate dehydrogenase
H5C80_02680	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H5C80_02690	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
H5C80_02700	COG0456	acetyltransferase
H5C80_02715	COG1011	Hydrolase
H5C80_02725	COG0477	Major facilitator Superfamily
H5C80_02735	COG1063	alcohol dehydrogenase
H5C80_02740	COG3684	Belongs to the aldolase LacD family
H5C80_02745	COG2084	Dehydrogenase
H5C80_02750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_02755	COG1349	DNA-binding transcription factor activity
H5C80_02760	COG2271	Major facilitator Superfamily
H5C80_02765	COG1082	Xylose isomerase domain protein TIM barrel
H5C80_02770	COG2188	Transcriptional regulator
H5C80_02780	COG0174	glutamine synthetase
H5C80_02785	COG3852	Histidine kinase
H5C80_02790	COG2204	response regulator
H5C80_02800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H5C80_02815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H5C80_02815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H5C80_02820	COG0204	Acyl-transferase
H5C80_02825	COG5339	Protein conserved in bacteria
H5C80_02830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H5C80_02835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H5C80_02840	COG3084	Protein conserved in bacteria
H5C80_02845	COG0746	molybdenum cofactor guanylyltransferase activity
H5C80_02850	COG1763	Mo-molybdopterin cofactor biosynthetic process
H5C80_02880	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H5C80_02885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H5C80_02890	COG1739	Uncharacterized protein family UPF0029
H5C80_02905	COG0183	Belongs to the thiolase family
H5C80_02910	COG0543	2 iron, 2 sulfur cluster binding
H5C80_02915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H5C80_02920	COG0250	Participates in transcription elongation, termination and antitermination
H5C80_02930	COG0805	protein transport
H5C80_02935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H5C80_02940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H5C80_02950	COG3165	ubiquinone biosynthetic process from chorismate
H5C80_02960	COG1322	Protein conserved in bacteria
H5C80_02965	COG1414	Transcriptional regulator
H5C80_02970	COG3734	2-keto-3-deoxy-galactonokinase
H5C80_02975	COG0800	Aldolase
H5C80_02995	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H5C80_03000	COG0412	Dienelactone hydrolase
H5C80_03005	COG1335	isochorismatase
H5C80_03015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C80_03020	COG1304	FMN binding
H5C80_03025	COG0549	Belongs to the carbamate kinase family
H5C80_03035	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H5C80_03040	COG0583	DNA-binding transcription factor activity
H5C80_03045	COG1737	Transcriptional regulator
H5C80_03050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H5C80_03055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_03055	COG1263	PTS System
H5C80_03055	COG2190	(PTS) system
H5C80_03070	COG0583	DNA-binding transcription factor activity
H5C80_03075	COG0697	spore germination
H5C80_03080	COG0561	phosphatase activity
H5C80_03085	COG2267	carboxylic ester hydrolase activity
H5C80_03090	COG1280	lysine exporter protein (LysE YggA)
H5C80_03095	COG1280	lysine exporter protein (LysE YggA)
H5C80_03100	COG0514	ATP-dependent DNA helicase (RecQ)
H5C80_03105	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
H5C80_03110	COG2050	protein possibly involved in aromatic compounds catabolism
H5C80_03115	COG2962	Rard protein
H5C80_03130	COG0598	Magnesium transport protein CorA
H5C80_03135	COG3698	Phosphodiester glycosidase
H5C80_03140	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
H5C80_03145	COG0210	DNA helicase
H5C80_03150	COG1011	Hydrolase
H5C80_03160	COG3159	Protein conserved in bacteria
H5C80_03170	COG5567	small periplasmic lipoprotein
H5C80_03190	COG3072	Adenylate cyclase
H5C80_03200	COG1587	Uroporphyrinogen-III synthase
H5C80_03205	COG2959	enzyme of heme biosynthesis
H5C80_03210	COG3071	HemY protein
H5C80_03215	COG3119	arylsulfatase activity
H5C80_03220	COG0641	radical SAM
H5C80_03245	COG1113	amino acid transport
H5C80_03265	COG2244	polysaccharide biosynthetic process
H5C80_03270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H5C80_03275	COG0456	acetyltransferase
H5C80_03280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H5C80_03285	COG1088	dTDP-glucose 4,6-dehydratase activity
H5C80_03290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H5C80_03295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H5C80_03300	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H5C80_03305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H5C80_03310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H5C80_03320	COG3118	belongs to the thioredoxin family
H5C80_03335	COG0210	DNA helicase
H5C80_03340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H5C80_03350	COG0583	DNA-binding transcription factor activity
H5C80_03355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H5C80_03365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H5C80_03370	COG3978	acetolactate synthase activity
H5C80_03390	COG0606	chelatase, subunit chli
H5C80_03395	COG3085	chromosome segregation
H5C80_03435	COG2186	Transcriptional regulator
H5C80_03440	COG0477	Major facilitator Superfamily
H5C80_03445	COG1609	Transcriptional regulator
H5C80_03450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_03455	COG1879	ABC-type sugar transport system periplasmic component
H5C80_03460	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C80_03465	COG1129	ABC transporter
H5C80_03495	COG1522	sequence-specific DNA binding
H5C80_03500	COG0716	FMN binding
H5C80_03515	COG3312	ion transport
H5C80_03590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H5C80_03595	COG0573	inorganic phosphate transmembrane transporter activity
H5C80_03600	COG0581	inorganic phosphate transmembrane transporter activity
H5C80_03605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H5C80_03610	COG0704	Plays a role in the regulation of phosphate uptake
H5C80_03615	COG3711	transcriptional antiterminator
H5C80_03620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_03620	COG1263	PTS System
H5C80_03620	COG2190	(PTS) system
H5C80_03625	COG2723	6-phospho-beta-galactosidase activity
H5C80_03635	COG2382	esterase
H5C80_03640	COG0363	glucosamine-6-phosphate deaminase activity
H5C80_03650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C80_03655	COG2252	PERMEase
H5C80_03660	COG0431	NADPH-dependent FMN reductase
H5C80_03665	COG2091	lysine biosynthetic process via aminoadipic acid
H5C80_03670	COG0583	DNA-binding transcription factor activity
H5C80_03680	COG0814	amino acid
H5C80_03730	COG0592	DNA-directed DNA polymerase activity
H5C80_03740	COG0187	DNA topoisomerase II activity
H5C80_03745	COG3753	Protein conserved in bacteria
H5C80_03750	COG0561	phosphatase activity
H5C80_03760	COG2186	Transcriptional regulator
H5C80_03765	COG3734	2-keto-3-deoxy-galactonokinase
H5C80_03770	COG0800	Aldolase
H5C80_03780	COG2271	Major facilitator Superfamily
H5C80_03785	COG0644	oxidoreductase
H5C80_03790	COG0823	Involved in the tonB-independent uptake of proteins
H5C80_03795	COG5645	(Lipo)protein
H5C80_03815	COG2207	Transcriptional regulator
H5C80_03820	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H5C80_03825	COG3119	arylsulfatase activity
H5C80_03830	COG2149	membrane
H5C80_03840	COG0641	radical SAM
H5C80_03845	COG2814	Major facilitator Superfamily
H5C80_03860	COG0028	Belongs to the TPP enzyme family
H5C80_03865	COG0440	acetolactate synthase activity
H5C80_03870	COG2197	response regulator
H5C80_03875	COG3851	Histidine kinase
H5C80_03880	COG2271	Major facilitator Superfamily
H5C80_03885	COG2271	Major facilitator Superfamily
H5C80_03895	COG2252	PERMEase
H5C80_03915	COG1464	Belongs to the NlpA lipoprotein family
H5C80_03920	COG0697	spore germination
H5C80_03940	COG2211	Major facilitator Superfamily
H5C80_03945	COG1501	Belongs to the glycosyl hydrolase 31 family
H5C80_03950	COG3711	transcriptional antiterminator
H5C80_03955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_03955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_03955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_03960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_03965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_03965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_03980	COG1940	carbohydrate kinase activity
H5C80_03990	COG2982	Protein involved in outer membrane biogenesis
H5C80_03995	COG2233	PERMEase
H5C80_04000	COG0786	glutamate:sodium symporter activity
H5C80_04005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H5C80_04010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H5C80_04015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H5C80_04025	COG0194	GDP metabolic process
H5C80_04035	COG2860	membrane
H5C80_04040	COG1561	YicC-like family, N-terminal region
H5C80_04065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H5C80_04095	COG1519	Transferase
H5C80_04100	COG0859	PFAM glycosyl transferase family 9
H5C80_04105	COG0438	transferase activity, transferring glycosyl groups
H5C80_04110	COG0515	serine threonine protein kinase
H5C80_04130	COG1442	glycosyl transferase family 8
H5C80_04140	COG3307	-O-antigen
H5C80_04145	COG0859	PFAM glycosyl transferase family 9
H5C80_04150	COG0859	PFAM glycosyl transferase family 9
H5C80_04160	COG0156	8-amino-7-oxononanoate synthase activity
H5C80_04170	COG1216	Glycosyl transferase, family 2
H5C80_04175	COG2861	carbohydrate metabolic process
H5C80_04180	COG4942	peptidase
H5C80_04190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H5C80_04195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H5C80_04210	COG1045	serine acetyltransferase
H5C80_04215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H5C80_04225	COG2186	Transcriptional regulator
H5C80_04230	COG1620	l-lactate permease
H5C80_04235	COG5295	Hep Hag repeat protein
H5C80_04255	COG3722	fumarate hydratase activity
H5C80_04265	COG2213	PTS system mannitol-specific
H5C80_04265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_04275	COG1566	PFAM secretion protein HlyD family protein
H5C80_04280	COG0625	glutathione transferase activity
H5C80_04290	COG3276	selenocysteine insertion sequence binding
H5C80_04295	COG1454	alcohol dehydrogenase
H5C80_04300	COG1012	belongs to the aldehyde dehydrogenase family
H5C80_04315	COG1566	PFAM secretion protein HlyD family protein
H5C80_04320	COG0583	DNA-binding transcription factor activity
H5C80_04325	COG3713	MltA-interacting MipA family protein
H5C80_04335	COG2211	Major facilitator Superfamily
H5C80_04345	COG0235	Class ii aldolase
H5C80_04350	COG3623	hexulose-6-phosphate isomerase
H5C80_04355	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H5C80_04360	COG1070	Carbohydrate kinase
H5C80_04365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H5C80_04370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H5C80_04375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H5C80_04380	COG2731	YhcH YjgK YiaL family protein
H5C80_04390	COG1414	Transcriptional regulator
H5C80_04395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_04400	COG3977	Valine--pyruvate aminotransferase
H5C80_04405	COG0366	Alpha amylase catalytic
H5C80_04410	COG2992	FlgJ-related protein
H5C80_04415	COG2207	Transcriptional regulator
H5C80_04415	COG1609	Transcriptional regulator
H5C80_04420	COG4214	carbohydrate transport
H5C80_04430	COG4213	ABC transporter substrate-binding protein
H5C80_04440	COG1070	Carbohydrate kinase
H5C80_04445	COG4682	membrane
H5C80_04450	COG4682	membrane
H5C80_04455	COG3274	enterobacterial common antigen metabolic process
H5C80_04480	COG1278	Cold shock
H5C80_04485	COG2944	sequence-specific DNA binding
H5C80_04500	COG2885	chlorophyll binding
H5C80_04505	COG0243	molybdopterin cofactor binding
H5C80_04510	COG0456	acetyltransferase
H5C80_04515	COG2818	Glycosylase
H5C80_04520	COG5571	outer membrane autotransporter
H5C80_04525	COG2223	nitrite transmembrane transporter activity
H5C80_04530	COG2194	sulfuric ester hydrolase activity
H5C80_04555	COG0747	negative chemotaxis
H5C80_04565	COG0601	transmembrane transport
H5C80_04570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H5C80_04575	COG0444	Belongs to the ABC transporter superfamily
H5C80_04580	COG4608	Belongs to the ABC transporter superfamily
H5C80_04585	COG0814	amino acid
H5C80_04610	COG2194	sulfuric ester hydrolase activity
H5C80_04635	COG1215	transferase activity, transferring glycosyl groups
H5C80_04640	COG1215	transferase activity, transferring glycosyl groups
H5C80_04645	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H5C80_04650	COG0457	Tetratricopeptide repeat
H5C80_04650	COG3118	belongs to the thioredoxin family
H5C80_04655	COG2200	EAL domain
H5C80_04655	COG2199	diguanylate cyclase activity
H5C80_04665	COG0612	Peptidase, M16
H5C80_04670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_04675	COG2200	EAL domain
H5C80_04680	COG2982	Protein involved in outer membrane biogenesis
H5C80_04685	COG0477	Major facilitator Superfamily
H5C80_04690	COG1295	ribonuclease BN
H5C80_04695	COG0583	DNA-binding transcription factor activity
H5C80_04700	COG2197	response regulator
H5C80_04710	COG1858	cytochrome C peroxidase
H5C80_04715	COG0076	glutamate decarboxylase activity
H5C80_04725	COG2207	Transcriptional regulator
H5C80_04730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C80_04735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_04745	COG2771	luxR family
H5C80_04750	COG3247	response to pH
H5C80_04765	COG1285	pathogenesis
H5C80_04775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_04785	COG3721	Heme iron utilization protein
H5C80_04795	COG4558	Periplasmic binding protein
H5C80_04800	COG4771	TonB-dependent receptor
H5C80_04805	COG3720	iron ion transport
H5C80_04810	COG2197	response regulator
H5C80_04815	COG3065	identical protein binding
H5C80_04835	COG1393	Belongs to the ArsC family
H5C80_04840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H5C80_04845	COG0640	Transcriptional regulator
H5C80_04860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H5C80_04865	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H5C80_04870	COG0339	signal peptide processing
H5C80_04880	COG3104	oligopeptide transport
H5C80_04885	COG0589	response to stress
H5C80_04895	COG0306	phosphate transporter
H5C80_04900	COG2081	HI0933 family
H5C80_04910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_04915	COG0842	Transport permease protein
H5C80_04915	COG1129	ABC transporter
H5C80_04920	COG0842	Transport permease protein
H5C80_04950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H5C80_04955	COG0601	transmembrane transport
H5C80_04960	COG0747	negative chemotaxis
H5C80_04965	COG2091	lysine biosynthetic process via aminoadipic acid
H5C80_04970	COG0628	permease
H5C80_04975	COG0477	Major facilitator Superfamily
H5C80_04985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H5C80_05000	COG3714	YhhN family
H5C80_05010	COG3776	membrane
H5C80_05015	COG0742	ribosomal rna small subunit methyltransferase
H5C80_05020	COG0552	protein localization to endoplasmic reticulum
H5C80_05025	COG2884	Cell division ATP-binding protein ftsE
H5C80_05030	COG2177	Part of the ABC transporter FtsEX involved in
H5C80_05035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H5C80_05040	COG0683	leucine binding
H5C80_05045	COG0456	acetyltransferase
H5C80_05050	COG0683	leucine binding
H5C80_05055	COG0559	Belongs to the binding-protein-dependent transport system permease family
H5C80_05060	COG4177	L-phenylalanine transmembrane transporter activity
H5C80_05065	COG0411	ABC transporter
H5C80_05070	COG0410	ABC transporter
H5C80_05085	COG1653	transport
H5C80_05090	COG1175	transmembrane transport
H5C80_05105	COG0584	glycerophosphoryl diester phosphodiesterase
H5C80_05115	COG0405	Gamma-glutamyltransferase
H5C80_05120	COG1247	-acetyltransferase
H5C80_05125	COG0673	inositol 2-dehydrogenase activity
H5C80_05130	COG1741	Belongs to the pirin family
H5C80_05135	COG1609	Transcriptional regulator
H5C80_05140	COG3265	gluconokinase activity
H5C80_05145	COG2610	gluconate transmembrane transporter activity
H5C80_05150	COG2095	MarC family integral membrane protein
H5C80_05155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H5C80_05160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H5C80_05180	COG0058	SHG alpha-glucan phosphorylase activity
H5C80_05190	COG3121	Chaperone
H5C80_05195	COG3188	usher protein
H5C80_05235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H5C80_05250	COG1349	DNA-binding transcription factor activity
H5C80_05255	COG4650	regulator
H5C80_05260	COG1690	Belongs to the RtcB family
H5C80_05275	COG0058	SHG alpha-glucan phosphorylase activity
H5C80_05280	COG1640	4-alpha-glucanotransferase
H5C80_05285	COG2610	gluconate transmembrane transporter activity
H5C80_05295	COG1040	competence protein
H5C80_05305	COG5464	transposase or invertase
H5C80_05315	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H5C80_05320	COG1918	ferrous iron import across plasma membrane
H5C80_05325	COG2183	response to ionizing radiation
H5C80_05330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H5C80_05335	COG0745	RESPONSE REGULATOR receiver
H5C80_05340	COG2205	protein histidine kinase activity
H5C80_05360	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H5C80_05370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H5C80_05375	COG1011	Hydrolase
H5C80_05385	COG0494	nUDIX hydrolase
H5C80_05390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H5C80_05395	COG4972	Pilus assembly protein
H5C80_05400	COG3166	PFAM Fimbrial assembly family protein
H5C80_05415	COG4796	Type ii and iii secretion system protein
H5C80_05430	COG3266	domain, Protein
H5C80_05435	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H5C80_05440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H5C80_05450	COG0180	Tryptophanyl-tRNA synthetase
H5C80_05455	COG2188	Transcriptional regulator
H5C80_05465	COG3457	Alanine racemase
H5C80_05470	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H5C80_05475	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H5C80_05490	COG0626	cystathionine gamma-synthase activity
H5C80_05505	COG2116	formate transmembrane transporter activity
H5C80_05510	COG2146	nitrite reductase [NAD(P)H] activity
H5C80_05515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H5C80_05525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H5C80_05535	COG2184	nucleotidyltransferase activity
H5C80_05540	COG0512	Glutamine amidotransferase of anthranilate synthase
H5C80_05545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H5C80_05550	COG1289	transmembrane transporter activity
H5C80_05555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H5C80_05560	COG1765	OsmC-like protein
H5C80_05565	COG3954	Phosphoribulokinase
H5C80_05575	COG0429	hydrolase of the alpha beta-hydrolase fold
H5C80_05580	COG0488	(ABC) transporter
H5C80_05595	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H5C80_05600	COG1047	Peptidyl-prolyl cis-trans
H5C80_05610	COG0545	Peptidyl-prolyl cis-trans isomerase
H5C80_05615	COG2964	Protein conserved in bacteria
H5C80_05655	COG3979	chitinase
H5C80_05660	COG2906	2 iron, 2 sulfur cluster binding
H5C80_05665	COG2193	ferroxidase activity
H5C80_05670	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H5C80_05675	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H5C80_05680	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H5C80_05685	COG3156	type II secretion system protein K
H5C80_05690	COG4795	General secretion pathway protein
H5C80_05695	COG2165	general secretion pathway protein
H5C80_05700	COG2165	general secretion pathway protein
H5C80_05705	COG2165	general secretion pathway protein
H5C80_05710	COG1459	type II secretion system
H5C80_05715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H5C80_05720	COG1450	Type ii and iii secretion system protein
H5C80_05725	COG3031	protein transport across the cell outer membrane
H5C80_05730	COG3409	Peptidoglycan-binding domain 1 protein
H5C80_05730	COG3267	Type II secretory pathway component ExeA
H5C80_05755	COG0089	rRNA binding
H5C80_05845	COG0201	protein transport
H5C80_05885	COG0789	Transcriptional regulator
H5C80_05890	COG3036	rescue of stalled ribosome
H5C80_05900	COG0569	domain protein
H5C80_05920	COG0758	DNA mediated transformation
H5C80_05930	COG0551	DNA topoisomerase type I activity
H5C80_05950	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H5C80_05990	COG1126	abc transporter atp-binding protein
H5C80_05995	COG0765	amino acid transport
H5C80_06000	COG4597	amino acid ABC transporter
H5C80_06005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C80_06015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C80_06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_06025	COG1309	transcriptional regulator
H5C80_06035	COG2189	Belongs to the N(4) N(6)-methyltransferase family
H5C80_06045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H5C80_06055	COG4145	pantothenate transmembrane transporter activity
H5C80_06060	COG3924	membrane
H5C80_06065	COG0439	Biotin carboxylase
H5C80_06070	COG0511	ligase activity, forming carbon-carbon bonds
H5C80_06085	COG0604	alcohol dehydrogenase
H5C80_06090	COG2200	EAL domain
H5C80_06090	COG2199	diguanylate cyclase activity
H5C80_06095	COG1077	Cell shape determining protein MreB Mrl
H5C80_06100	COG1792	Involved in formation and maintenance of cell shape
H5C80_06105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H5C80_06115	COG1530	ribonuclease E activity
H5C80_06120	COG3164	Protein of unknown function
H5C80_06125	COG0312	modulator of DNA gyrase
H5C80_06130	COG0583	DNA-binding transcription factor activity
H5C80_06150	COG2732	(Barnase) inhibitor
H5C80_06170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H5C80_06175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H5C80_06180	COG3105	Protein conserved in bacteria
H5C80_06185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H5C80_06200	COG0625	glutathione transferase activity
H5C80_06205	COG2969	positive regulation of protein catabolic process
H5C80_06210	COG3069	C4-dicarboxylate transmembrane transporter activity
H5C80_06240	COG2731	YhcH YjgK YiaL family protein
H5C80_06245	COG4804	nuclease activity
H5C80_06250	COG0493	'glutamate synthase
H5C80_06255	COG0067	glutamate synthase
H5C80_06255	COG0069	glutamate synthase activity
H5C80_06255	COG0070	glutamate synthase
H5C80_06260	COG1242	4 iron, 4 sulfur cluster binding
H5C80_06265	COG5002	protein histidine kinase activity
H5C80_06265	COG2198	Histidine kinase
H5C80_06265	COG0784	Response regulator, receiver
H5C80_06270	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H5C80_06280	COG0515	serine threonine protein kinase
H5C80_06285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_06300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H5C80_06305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H5C80_06310	COG1137	ATPase activity
H5C80_06315	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H5C80_06320	COG3117	lipopolysaccharide transmembrane transporter activity
H5C80_06325	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H5C80_06330	COG0517	IMP dehydrogenase activity
H5C80_06330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H5C80_06335	COG0530	calcium, potassium:sodium antiporter activity
H5C80_06340	COG1127	ABC transporter
H5C80_06345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H5C80_06350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H5C80_06355	COG2854	intermembrane phospholipid transfer
H5C80_06360	COG3113	response to antibiotic
H5C80_06365	COG5007	Belongs to the BolA IbaG family
H5C80_06375	COG3423	Transcriptional regulator
H5C80_06380	COG0142	geranyltranstransferase activity
H5C80_06395	COG0697	spore germination
H5C80_06405	COG2027	D-alanyl-D-alanine carboxypeptidase
H5C80_06410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H5C80_06415	COG1534	Rna-binding protein
H5C80_06425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H5C80_06430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H5C80_06440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H5C80_06450	COG2194	sulfuric ester hydrolase activity
H5C80_06470	COG0195	Participates in both transcription termination and antitermination
H5C80_06510	COG0513	Belongs to the DEAD box helicase family
H5C80_06515	COG0814	amino acid
H5C80_06520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H5C80_06525	COG0826	peptidase U32
H5C80_06530	COG0826	peptidase U32
H5C80_06535	COG3154	lipid carrier protein
H5C80_06540	COG3153	acetyltransferase
H5C80_06555	COG0693	protein deglycase activity
H5C80_06560	COG0702	epimerase
H5C80_06565	COG0701	Predicted permease
H5C80_06570	COG2823	Periplasmic or secreted lipoprotein
H5C80_06590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H5C80_06595	COG0363	glucosamine-6-phosphate deaminase activity
H5C80_06600	COG3716	PTS system mannose fructose sorbose family IID component
H5C80_06605	COG3715	PTS system
H5C80_06610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_06620	COG2222	sugar isomerase
H5C80_06625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H5C80_06630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_06635	COG3716	PTS system mannose fructose sorbose family IID component
H5C80_06645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_06655	COG1349	DNA-binding transcription factor activity
H5C80_06665	COG2002	toxin-antitoxin pair type II binding
H5C80_06670	COG2721	sulfolactate sulfo-lyase activity
H5C80_06675	COG2271	Major facilitator Superfamily
H5C80_06685	COG2084	Dehydrogenase
H5C80_06690	COG1929	Belongs to the glycerate kinase type-1 family
H5C80_06705	COG0583	DNA-binding transcription factor activity
H5C80_06710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H5C80_06720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H5C80_06725	COG1882	Formate acetyltransferase
H5C80_06730	COG0251	oxidation-reduction process
H5C80_06735	COG1760	l-serine dehydratase
H5C80_06740	COG0814	amino acid
H5C80_06755	COG1741	Belongs to the pirin family
H5C80_06760	COG0583	DNA-binding transcription factor activity
H5C80_06765	COG3152	Membrane
H5C80_06770	COG3152	Membrane
H5C80_06775	COG0435	Glutathione S-transferase
H5C80_06780	COG2259	Doxx family
H5C80_06790	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H5C80_06795	COG4575	ribosome binding
H5C80_06800	COG1422	Protein of unknown function (DUF1090)
H5C80_06810	COG0586	Pfam SNARE associated Golgi protein
H5C80_06815	COG2186	Transcriptional regulator
H5C80_06820	COG2271	Major facilitator Superfamily
H5C80_06830	COG2721	sulfolactate sulfo-lyase activity
H5C80_06840	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H5C80_06845	COG0861	Integral membrane protein TerC family
H5C80_06850	COG0673	inositol 2-dehydrogenase activity
H5C80_06855	COG2949	membrane
H5C80_06860	COG1451	nucleotide metabolic process
H5C80_06875	COG5499	transcription regulator containing HTH domain
H5C80_06880	COG1902	pentaerythritol trinitrate reductase activity
H5C80_06880	COG0446	pyridine nucleotide-disulphide oxidoreductase
H5C80_06885	COG3408	Glycogen debranching enzyme
H5C80_06885	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H5C80_06895	COG0531	amino acid
H5C80_06900	COG2731	YhcH YjgK YiaL family protein
H5C80_06905	COG3250	beta-galactosidase activity
H5C80_06910	COG1609	Transcriptional regulator
H5C80_06915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H5C80_06925	COG0840	transmembrane signaling receptor activity
H5C80_06930	COG1695	Transcriptional regulator
H5C80_06935	COG2375	cellular response to nickel ion
H5C80_06955	COG3311	Transcriptional regulator
H5C80_07030	COG1802	Transcriptional regulator
H5C80_07030	COG4626	Terminase
H5C80_07050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H5C80_07055	COG0358	DNA primase activity
H5C80_07060	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H5C80_07075	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C80_07080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C80_07095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H5C80_07110	COG4991	sh3 domain protein
H5C80_07115	COG3025	triphosphatase activity
H5C80_07135	COG2268	Band 7 protein
H5C80_07140	COG1585	Membrane protein implicated in regulation of membrane protease activity
H5C80_07170	COG3384	dioxygenase
H5C80_07180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H5C80_07190	COG0754	glutathionylspermidine amidase activity
H5C80_07200	COG1538	Outer membrane efflux protein
H5C80_07205	COG0494	nUDIX hydrolase
H5C80_07210	COG3151	Protein conserved in bacteria
H5C80_07215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H5C80_07220	COG3150	esterase
H5C80_07225	COG0187	DNA topoisomerase II activity
H5C80_07245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_07265	COG2211	Major facilitator Superfamily
H5C80_07270	COG4774	siderophore transport
H5C80_07275	COG1120	ATPase activity
H5C80_07280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_07285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_07295	COG1737	Transcriptional regulator
H5C80_07300	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H5C80_07305	COG2249	NAD(P)H dehydrogenase (quinone) activity
H5C80_07310	COG0642	Histidine kinase
H5C80_07315	COG0745	RESPONSE REGULATOR receiver
H5C80_07320	COG3111	PFAM Bacterial OB fold (BOF) protein
H5C80_07325	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H5C80_07330	COG4166	transmembrane transport
H5C80_07335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H5C80_07340	COG0204	Acyl-transferase
H5C80_07345	COG2132	Multicopper oxidase
H5C80_07350	COG1032	radical SAM domain protein
H5C80_07355	COG4238	major outer membrane lipoprotein
H5C80_07365	COG0656	L-ascorbic acid biosynthetic process
H5C80_07370	COG1979	alcohol dehydrogenase
H5C80_07375	COG2207	Transcriptional regulator
H5C80_07380	COG0586	Pfam SNARE associated Golgi protein
H5C80_07385	COG0626	cystathionine gamma-synthase activity
H5C80_07390	COG0811	peptide transport
H5C80_07395	COG0848	biopolymer transport protein
H5C80_07400	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_07410	COG0667	Aldo Keto reductase
H5C80_07425	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H5C80_07430	COG0437	4 iron, 4 sulfur cluster binding
H5C80_07435	COG5557	Pfam Polysulphide reductase, NrfD
H5C80_07440	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H5C80_07445	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H5C80_07450	COG1773	rubredoxin
H5C80_07455	COG0375	protein maturation
H5C80_07460	COG0298	carbon dioxide binding
H5C80_07465	COG0625	glutathione transferase activity
H5C80_07470	COG0754	glutathionylspermidine amidase activity
H5C80_07475	COG0306	phosphate transporter
H5C80_07480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H5C80_07485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H5C80_07490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H5C80_07495	COG2244	polysaccharide biosynthetic process
H5C80_07505	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H5C80_07510	COG0795	lipopolysaccharide-transporting ATPase activity
H5C80_07520	COG0156	8-amino-7-oxononanoate synthase activity
H5C80_07525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H5C80_07540	COG0456	acetyltransferase
H5C80_07545	COG2186	Transcriptional regulator
H5C80_07550	COG0277	FAD linked oxidase domain protein
H5C80_07555	COG0277	FAD linked oxidase domain protein
H5C80_07560	COG0247	lactate metabolic process
H5C80_07565	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H5C80_07570	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H5C80_07575	COG1620	l-lactate permease
H5C80_07580	COG3064	Membrane
H5C80_07585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H5C80_07605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H5C80_07610	COG1459	type II secretion system
H5C80_07615	COG2165	general secretion pathway protein
H5C80_07630	COG4795	General secretion pathway protein
H5C80_07645	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H5C80_07680	COG2003	Belongs to the UPF0758 family
H5C80_07705	COG2378	regulation of single-species biofilm formation
H5C80_07710	COG3596	GTP binding
H5C80_07750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H5C80_07775	COG2194	sulfuric ester hydrolase activity
H5C80_07780	COG0582	viral genome integration into host DNA
H5C80_07790	COG3609	addiction module antidote protein, CC2985 family
H5C80_07825	COG2003	Belongs to the UPF0758 family
H5C80_07850	COG2378	regulation of single-species biofilm formation
H5C80_07855	COG3596	GTP binding
H5C80_08055	COG2916	Histone family protein nucleoid-structuring protein H-NS
H5C80_08085	COG2194	sulfuric ester hydrolase activity
H5C80_08090	COG0582	viral genome integration into host DNA
H5C80_08115	COG0305	Participates in initiation and elongation during chromosome replication
H5C80_08205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H5C80_08225	COG0629	single-stranded DNA binding
H5C80_08345	COG4771	TonB-dependent receptor
H5C80_08515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H5C80_08560	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H5C80_08570	COG1811	Na channel or pump
H5C80_08575	COG1982	Orn Lys Arg decarboxylase major
H5C80_08580	COG2211	Major facilitator Superfamily
H5C80_08595	COG1194	a g-specific adenine glycosylase
H5C80_08605	COG3171	Protein conserved in bacteria
H5C80_08615	COG0252	asparaginase activity
H5C80_08630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H5C80_08635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H5C80_08640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H5C80_08655	COG0762	integral membrane protein
H5C80_08660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H5C80_08665	COG2805	Type II/IV secretion system protein
H5C80_08680	COG0189	ligase activity
H5C80_08685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H5C80_08690	COG2356	endonuclease I
H5C80_08700	COG2814	Major facilitator Superfamily
H5C80_08720	COG1166	arginine decarboxylase activity
H5C80_08735	COG0501	Belongs to the peptidase M48B family
H5C80_08740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H5C80_08745	COG0330	HflC and HflK could
H5C80_08750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_08755	COG2213	PTS system mannitol-specific
H5C80_08760	COG1063	alcohol dehydrogenase
H5C80_08765	COG1494	fructose-1,6-bisphosphatase
H5C80_08775	COG1072	(Pantothenic acid kinase))
H5C80_08790	COG0191	fructose-bisphosphate aldolase activity
H5C80_08795	COG0668	transmembrane transport
H5C80_08800	COG1279	arginine transmembrane transporter activity
H5C80_08805	COG2968	Membrane
H5C80_08810	COG0583	DNA-binding transcription factor activity
H5C80_08815	COG0427	acetyl-CoA hydrolase
H5C80_08820	COG1024	Enoyl-CoA hydratase
H5C80_08825	COG1703	isobutyryl-CoA mutase activity
H5C80_08830	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H5C80_08830	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H5C80_08850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H5C80_08860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H5C80_08880	COG0006	proline dipeptidase activity
H5C80_08885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H5C80_08890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H5C80_08915	COG2723	6-phospho-beta-galactosidase activity
H5C80_08925	COG1272	protein, Hemolysin III
H5C80_08935	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H5C80_08945	COG0716	FMN binding
H5C80_08950	COG4974	Belongs to the 'phage' integrase family
H5C80_08955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H5C80_08960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H5C80_08970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H5C80_08985	COG2233	PERMEase
H5C80_08995	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_09000	COG2252	PERMEase
H5C80_09005	COG0402	S-adenosylhomocysteine deaminase activity
H5C80_09010	COG2233	PERMEase
H5C80_09015	COG2080	2 iron, 2 sulfur cluster binding
H5C80_09015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H5C80_09020	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H5C80_09025	COG0402	S-adenosylhomocysteine deaminase activity
H5C80_09030	COG0493	'glutamate synthase
H5C80_09030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_09035	COG2068	MobA-Related Protein
H5C80_09040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H5C80_09045	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H5C80_09045	COG3608	succinylglutamate desuccinylase aspartoacylase
H5C80_09050	COG0549	Belongs to the carbamate kinase family
H5C80_09060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H5C80_09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H5C80_09070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H5C80_09080	COG2080	2 iron, 2 sulfur cluster binding
H5C80_09085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H5C80_09090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H5C80_09095	COG4942	peptidase
H5C80_09105	COG0814	amino acid
H5C80_09110	COG0183	Belongs to the thiolase family
H5C80_09120	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_09125	COG2814	Major facilitator Superfamily
H5C80_09130	COG1794	racemase activity, acting on amino acids and derivatives
H5C80_09135	COG0583	DNA-binding transcription factor activity
H5C80_09145	COG1609	Transcriptional regulator
H5C80_09160	COG0667	Aldo Keto reductase
H5C80_09170	COG0861	Integral membrane protein TerC family
H5C80_09185	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
H5C80_09200	COG2165	general secretion pathway protein
H5C80_09205	COG4795	General secretion pathway protein
H5C80_09215	COG4967	type IV pilus modification protein PilV
H5C80_09220	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H5C80_09230	COG1074	ATP-dependent DNA helicase activity
H5C80_09235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H5C80_09240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H5C80_09240	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H5C80_09245	COG0860	N-Acetylmuramoyl-L-alanine amidase
H5C80_09250	COG3711	transcriptional antiterminator
H5C80_09255	COG1263	PTS System
H5C80_09255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_09260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H5C80_09350	COG2885	chlorophyll binding
H5C80_09385	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H5C80_09395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H5C80_09400	COG2166	iron-sulfur cluster assembly
H5C80_09405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H5C80_09415	COG0583	DNA-binding transcription factor activity
H5C80_09420	COG2363	Small membrane protein
H5C80_09430	COG1349	DNA-binding transcription factor activity
H5C80_09440	COG1070	Carbohydrate kinase
H5C80_09450	COG0738	Major facilitator superfamily
H5C80_09455	COG0235	Class ii aldolase
H5C80_09460	COG1454	alcohol dehydrogenase
H5C80_09470	COG1760	l-serine dehydratase
H5C80_09475	COG0814	amino acid
H5C80_09480	COG1611	Belongs to the LOG family
H5C80_09495	COG3098	single-species biofilm formation
H5C80_09500	COG0564	pseudouridine synthase activity
H5C80_09505	COG0716	FMN binding
H5C80_09510	COG2271	Major facilitator Superfamily
H5C80_09515	COG4948	Mandelate Racemase Muconate Lactonizing
H5C80_09520	COG4948	Mandelate Racemase Muconate Lactonizing
H5C80_09525	COG2205	protein histidine kinase activity
H5C80_09525	COG3437	response regulator, receiver
H5C80_09525	COG4999	Histidine kinase
H5C80_09525	COG3850	Histidine kinase
H5C80_09535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H5C80_09540	COG3956	TIGRFAM MazG family protein
H5C80_09560	COG0602	queuosine metabolic process
H5C80_09565	COG1070	Carbohydrate kinase
H5C80_09570	COG2223	nitrite transmembrane transporter activity
H5C80_09575	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_09580	COG0277	FAD linked oxidase domain protein
H5C80_09585	COG0477	Major facilitator Superfamily
H5C80_09590	COG2086	electron transfer activity
H5C80_09595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H5C80_09600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H5C80_09605	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H5C80_09610	COG0644	oxidoreductase
H5C80_09615	COG0720	synthase
H5C80_09640	COG3385	transposase activity
H5C80_09645	COG1203	CRISPR-associated helicase, Cas3
H5C80_09660	COG1857	crispr-associated protein
H5C80_09675	COG1518	maintenance of DNA repeat elements
H5C80_09680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C80_09685	COG2234	aminopeptidase activity
H5C80_09725	COG0585	pseudouridine synthase activity
H5C80_09740	COG1388	LysM domain
H5C80_09740	COG4942	peptidase
H5C80_09745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H5C80_09755	COG0163	prenyltransferase activity
H5C80_09760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H5C80_09770	COG2610	gluconate transmembrane transporter activity
H5C80_09775	COG3622	Belongs to the hyi family
H5C80_09780	COG0235	Class ii aldolase
H5C80_09785	COG3395	kinase activity
H5C80_09790	COG2084	Dehydrogenase
H5C80_09795	COG1349	DNA-binding transcription factor activity
H5C80_09800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H5C80_09825	COG3604	Transcriptional regulator
H5C80_09830	COG0309	Hydrogenase expression formation protein (HypE)
H5C80_09835	COG0409	Hydrogenase expression formation protein
H5C80_09840	COG0298	carbon dioxide binding
H5C80_09845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H5C80_09850	COG0375	protein maturation
H5C80_09860	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_09865	COG0651	ATP synthesis coupled electron transport
H5C80_09870	COG0650	Formate hydrogenlyase subunit 4
H5C80_09875	COG3261	NADH dehydrogenase
H5C80_09875	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H5C80_09880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H5C80_09885	COG3260	NADH ubiquinone oxidoreductase 20
H5C80_09895	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H5C80_09900	COG2723	6-phospho-beta-galactosidase activity
H5C80_09905	COG1263	PTS System
H5C80_09905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_09910	COG1609	Transcriptional regulator
H5C80_09915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_09920	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H5C80_09940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H5C80_09940	COG0517	IMP dehydrogenase activity
H5C80_09945	COG1349	DNA-binding transcription factor activity
H5C80_09950	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_09955	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_09965	COG3732	PTS system glucitol sorbitol-specific
H5C80_09970	COG3730	PTS system glucitol sorbitol-specific
H5C80_09975	COG2951	lytic endotransglycosylase activity
H5C80_09980	COG1546	Belongs to the CinA family
H5C80_10000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H5C80_10030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C80_10035	COG1238	metal cluster binding
H5C80_10050	COG2814	Major facilitator Superfamily
H5C80_10055	COG1566	PFAM secretion protein HlyD family protein
H5C80_10060	COG1846	Transcriptional regulator
H5C80_10070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H5C80_10075	COG2814	Major facilitator Superfamily
H5C80_10080	COG2113	Glycine betaine
H5C80_10085	COG4176	ABC-type proline glycine betaine transport system permease component
H5C80_10090	COG4175	Glycine betaine
H5C80_10095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C80_10100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C80_10110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H5C80_10115	COG4575	ribosome binding
H5C80_10130	COG2916	Histone family protein nucleoid-structuring protein H-NS
H5C80_10135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H5C80_10140	COG0640	Transcriptional regulator
H5C80_10145	COG0401	homolog of Blt101
H5C80_10150	COG1652	LysM domain
H5C80_10155	COG1802	Transcriptional regulator
H5C80_10160	COG1113	amino acid transport
H5C80_10165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H5C80_10170	COG1012	belongs to the aldehyde dehydrogenase family
H5C80_10175	COG0579	oxidoreductase
H5C80_10195	COG2867	negative regulation of translational initiation
H5C80_10205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C80_10210	COG0497	DNA recombination
H5C80_10225	COG4536	flavin adenine dinucleotide binding
H5C80_10230	COG4137	Cytochrome C assembly protein
H5C80_10235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H5C80_10260	COG2885	chlorophyll binding
H5C80_10265	COG2199	diguanylate cyclase activity
H5C80_10280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H5C80_10285	COG0287	Prephenate dehydrogenase
H5C80_10285	COG1605	Chorismate mutase
H5C80_10290	COG1605	Chorismate mutase
H5C80_10290	COG0077	Prephenate dehydratase
H5C80_10300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H5C80_10310	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C80_10315	COG0564	pseudouridine synthase activity
H5C80_10325	COG0542	response to heat
H5C80_10350	COG0477	Major facilitator Superfamily
H5C80_10355	COG5544	Lipoprotein
H5C80_10360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H5C80_10365	COG1042	CoA-binding domain protein
H5C80_10365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C80_10365	COG0045	succinate-CoA ligase (ADP-forming) activity
H5C80_10375	COG3118	belongs to the thioredoxin family
H5C80_10380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H5C80_10400	COG0583	DNA-binding transcription factor activity
H5C80_10405	COG0513	Belongs to the DEAD box helicase family
H5C80_10415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H5C80_10425	COG1595	DNA-templated transcription, initiation
H5C80_10430	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H5C80_10435	COG3026	antisigma factor binding
H5C80_10440	COG3086	response to oxidative stress
H5C80_10450	COG0681	Belongs to the peptidase S26 family
H5C80_10470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H5C80_10485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_10490	COG1737	Transcriptional regulator
H5C80_10495	COG0560	Phosphoserine phosphatase
H5C80_10510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H5C80_10510	COG0047	phosphoribosylformylglycinamidine synthase activity
H5C80_10515	COG2205	protein histidine kinase activity
H5C80_10520	COG3170	Tfp pilus assembly protein FimV
H5C80_10525	COG2204	response regulator
H5C80_10530	COG0347	Belongs to the P(II) protein family
H5C80_10535	COG1017	nitric oxide dioxygenase activity
H5C80_10535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C80_10545	COG1940	carbohydrate kinase activity
H5C80_10550	COG0457	Tetratricopeptide repeat
H5C80_10555	COG1879	ABC-type sugar transport system periplasmic component
H5C80_10560	COG1129	ABC transporter
H5C80_10565	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C80_10570	COG1063	alcohol dehydrogenase
H5C80_10575	COG2017	converts alpha-aldose to the beta-anomer
H5C80_10580	COG2259	Doxx family
H5C80_10605	COG4638	Rieske (2fe-2S)
H5C80_10610	COG0583	DNA-binding transcription factor activity
H5C80_10615	COG2814	Major facilitator Superfamily
H5C80_10620	COG3711	transcriptional antiterminator
H5C80_10625	COG1073	alpha beta
H5C80_10630	COG0483	inositol monophosphate 1-phosphatase activity
H5C80_10650	COG0822	iron-sulfur transferase activity
H5C80_10670	COG0633	Ferredoxin
H5C80_10675	COG2975	iron-sulfur cluster assembly
H5C80_10690	COG2897	thiosulfate sulfurtransferase activity
H5C80_10695	COG2373	Large extracellular alpha-helical protein
H5C80_10700	COG4953	penicillin-binding protein 1C
H5C80_10730	COG2976	Protein conserved in bacteria
H5C80_10745	COG1645	bacterial-type flagellum-dependent swarming motility
H5C80_10770	COG0516	GMP reductase activity
H5C80_10770	COG0517	IMP dehydrogenase activity
H5C80_10785	COG3133	Outer membrane lipoprotein
H5C80_10800	COG2200	EAL domain
H5C80_10805	COG0248	Ppx GppA phosphatase
H5C80_10810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H5C80_10815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H5C80_10830	COG2233	PERMEase
H5C80_10840	COG1393	Belongs to the ArsC family
H5C80_10845	COG4783	chaperone-mediated protein folding
H5C80_10850	COG0628	permease
H5C80_10855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H5C80_10860	COG2716	regulation of RNA biosynthetic process
H5C80_10870	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H5C80_10890	COG2321	neutral zinc metallopeptidase
H5C80_10900	COG0400	carboxylic ester hydrolase activity
H5C80_10915	COG1393	Belongs to the ArsC family
H5C80_10925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C80_10930	COG3850	Histidine kinase
H5C80_10935	COG0493	'glutamate synthase
H5C80_10935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_10945	COG5342	invasion associated locus B
H5C80_10950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H5C80_10955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H5C80_10960	COG0280	phosphate acetyltransferase
H5C80_10960	COG0281	malic enzyme
H5C80_10965	COG4810	utilization protein
H5C80_10970	COG4917	ethanolamine utilization protein
H5C80_10975	COG4766	ethanolamine catabolic process
H5C80_10980	COG4812	Cobalamin adenosyltransferase
H5C80_10985	COG0280	phosphate acetyltransferase
H5C80_10990	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H5C80_10995	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
H5C80_11000	COG1012	belongs to the aldehyde dehydrogenase family
H5C80_11005	COG4820	ethanolamine utilization protein (EutJ)
H5C80_11010	COG1454	alcohol dehydrogenase
H5C80_11015	COG3192	ethanolamine utilization protein
H5C80_11020	COG4819	ethanolamine utilization protein
H5C80_11025	COG4303	Ethanolamine ammonia lyase large subunit
H5C80_11035	COG4816	utilization protein
H5C80_11040	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H5C80_11045	COG2207	Transcriptional regulator
H5C80_11055	COG0860	N-Acetylmuramoyl-L-alanine amidase
H5C80_11075	COG2837	iron assimilation
H5C80_11080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H5C80_11085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_11085	COG1263	PTS System
H5C80_11100	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_11105	COG4150	thiosulfate binding
H5C80_11110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H5C80_11115	COG4208	sulfate ABC transporter
H5C80_11120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H5C80_11125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H5C80_11140	COG2190	(PTS) system
H5C80_11145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C80_11150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_11155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H5C80_11175	COG3530	Putative quorum-sensing-regulated virulence factor
H5C80_11180	COG0385	Bile acid
H5C80_11185	COG0583	DNA-binding transcription factor activity
H5C80_11195	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H5C80_11200	COG2211	Major facilitator Superfamily
H5C80_11210	COG0583	DNA-binding transcription factor activity
H5C80_11240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H5C80_11245	COG3415	Transposase
H5C80_11250	COG3415	Transposase
H5C80_11265	COG2200	EAL domain
H5C80_11265	COG2199	diguanylate cyclase activity
H5C80_11270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H5C80_11295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_11300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_11305	COG0006	proline dipeptidase activity
H5C80_11310	COG1363	Peptidase, m42
H5C80_11315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_11315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_11315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C80_11320	COG2207	Transcriptional regulator
H5C80_11325	COG3279	Response regulator of the LytR AlgR family
H5C80_11330	COG3275	phosphorelay sensor kinase activity
H5C80_11335	COG0436	Aminotransferase
H5C80_11345	COG1560	Kdo2-lipid A biosynthetic process
H5C80_11370	COG0028	Belongs to the TPP enzyme family
H5C80_11375	COG0679	Auxin Efflux Carrier
H5C80_11380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H5C80_11390	COG2197	response regulator
H5C80_11395	COG1566	PFAM secretion protein HlyD family protein
H5C80_11400	COG0477	Major facilitator Superfamily
H5C80_11445	COG2116	formate transmembrane transporter activity
H5C80_11450	COG2853	Lipoprotein
H5C80_11455	COG2067	long-chain fatty acid transport protein
H5C80_11460	COG3691	Protein conserved in bacteria
H5C80_11475	COG2062	phosphohistidine phosphatase, SixA
H5C80_11480	COG3539	Fimbrial protein
H5C80_11485	COG3188	usher protein
H5C80_11490	COG3121	Chaperone
H5C80_11495	COG3539	Fimbrial protein
H5C80_11500	COG3539	Fimbrial protein
H5C80_11505	COG3539	Fimbrial protein
H5C80_11535	COG0730	response to heat
H5C80_11540	COG3101	peptidyl-lysine hydroxylation
H5C80_11555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H5C80_11560	COG2814	Major facilitator Superfamily
H5C80_11575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H5C80_11585	COG0586	Pfam SNARE associated Golgi protein
H5C80_11595	COG0285	dihydrofolate synthase activity
H5C80_11600	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H5C80_11605	COG1286	toxin biosynthetic process
H5C80_11610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H5C80_11615	COG0163	prenyltransferase activity
H5C80_11620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C80_11625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C80_11630	COG4215	(ABC) transporter
H5C80_11635	COG4160	amino acid transport
H5C80_11640	COG4598	ABC transporter
H5C80_11645	COG5464	transposase or invertase
H5C80_11650	COG1090	epimerase
H5C80_11655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H5C80_11660	COG0625	glutathione transferase activity
H5C80_11665	COG0625	glutathione transferase activity
H5C80_11670	COG0622	Phosphoesterase
H5C80_11675	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H5C80_11680	COG1288	antiporter activity
H5C80_11685	COG0280	phosphate acetyltransferase
H5C80_11685	COG0857	belongs to the CobB CobQ family
H5C80_11690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H5C80_11705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C80_11710	COG0471	metal ion transport
H5C80_11710	COG0490	domain, Protein
H5C80_11720	COG0436	Aminotransferase
H5C80_11725	COG0583	DNA-binding transcription factor activity
H5C80_11745	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H5C80_11750	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H5C80_11755	COG1034	ATP synthesis coupled electron transport
H5C80_11770	COG0839	Belongs to the complex I subunit 6 family
H5C80_11780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H5C80_11785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H5C80_11800	COG2234	aminopeptidase activity
H5C80_11805	COG5160	protein modification by small protein removal
H5C80_11815	COG2153	protein acetylation
H5C80_11820	COG4575	ribosome binding
H5C80_11825	COG1169	isochorismate synthase
H5C80_11840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H5C80_11845	COG1441	menaquinone biosynthetic process
H5C80_11850	COG0318	PFAM AMP-dependent synthetase and ligase
H5C80_11870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H5C80_11920	COG2271	Major facilitator Superfamily
H5C80_11935	COG5464	transposase or invertase
H5C80_11940	COG0247	lactate metabolic process
H5C80_11950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H5C80_11955	COG2271	Major facilitator Superfamily
H5C80_11960	COG0584	glycerophosphoryl diester phosphodiesterase
H5C80_11965	COG3642	lipopolysaccharide core region biosynthetic process
H5C80_11970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C80_11975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C80_11980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H5C80_11985	COG3468	outer membrane autotransporter barrel domain protein
H5C80_11995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H5C80_12000	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
H5C80_12005	COG3234	Protein of unknown function (DUF1175)
H5C80_12010	COG2373	Large extracellular alpha-helical protein
H5C80_12015	COG5445	Predicted secreted protein (DUF2300)
H5C80_12020	COG4676	Protein conserved in bacteria
H5C80_12025	COG0183	Belongs to the thiolase family
H5C80_12030	COG2031	fatty acid transporter
H5C80_12035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H5C80_12040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H5C80_12045	COG2204	response regulator
H5C80_12050	COG3852	Histidine kinase
H5C80_12055	COG2205	protein histidine kinase activity
H5C80_12055	COG0784	Response regulator, receiver
H5C80_12060	COG2197	response regulator
H5C80_12065	COG0642	Histidine kinase
H5C80_12065	COG2198	Histidine kinase
H5C80_12070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C80_12075	COG1477	protein flavinylation
H5C80_12080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H5C80_12080	COG2169	Transcriptional regulator
H5C80_12085	COG3145	DNA-N1-methyladenine dioxygenase activity
H5C80_12090	COG4615	Cyclic peptide transporter
H5C80_12105	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_12105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H5C80_12110	COG3062	negative regulation of establishment of protein localization
H5C80_12120	COG0437	4 iron, 4 sulfur cluster binding
H5C80_12125	COG0348	domain, Protein
H5C80_12130	COG3043	anaerobic respiration
H5C80_12135	COG3005	denitrification pathway
H5C80_12140	COG4133	protoheme IX ABC transporter activity
H5C80_12145	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H5C80_12150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H5C80_12155	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H5C80_12165	COG1138	Cytochrome C-type biogenesis protein
H5C80_12170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H5C80_12175	COG3088	subunit of a heme lyase
H5C80_12175	COG4235	cytochrome complex assembly
H5C80_12180	COG2197	response regulator
H5C80_12195	COG3083	sulfuric ester hydrolase activity
H5C80_12215	COG1061	Type III restriction enzyme res subunit
H5C80_12220	COG1187	pseudouridine synthase activity
H5C80_12225	COG2814	Major facilitator Superfamily
H5C80_12235	COG4172	Belongs to the ABC transporter superfamily
H5C80_12240	COG4239	(ABC) transporter, permease
H5C80_12245	COG4174	ABC transporter (Permease)
H5C80_12250	COG4166	transmembrane transport
H5C80_12255	COG2200	EAL domain
H5C80_12260	COG0791	NLP P60 protein
H5C80_12265	COG0671	phosphoesterase, PA-phosphatase related
H5C80_12270	COG0523	cobalamin synthesis protein
H5C80_12275	COG0246	Mannitol dehydrogenase
H5C80_12290	COG2814	Major facilitator Superfamily
H5C80_12295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_12295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_12300	COG1105	Belongs to the carbohydrate kinase PfkB family
H5C80_12305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_12305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H5C80_12305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H5C80_12310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_12315	COG2313	pseudouridylate synthase activity
H5C80_12320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H5C80_12325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H5C80_12335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H5C80_12340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_12340	COG1522	sequence-specific DNA binding
H5C80_12350	COG2855	membrane
H5C80_12355	COG0583	DNA-binding transcription factor activity
H5C80_12360	COG0833	amino acid
H5C80_12380	COG2311	Membrane
H5C80_12385	COG1609	Transcriptional regulator
H5C80_12390	COG1879	ABC-type sugar transport system periplasmic component
H5C80_12395	COG1129	ABC transporter
H5C80_12400	COG4211	Belongs to the binding-protein-dependent transport system permease family
H5C80_12405	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H5C80_12405	COG0167	dihydroorotate dehydrogenase activity
H5C80_12410	COG0493	'glutamate synthase
H5C80_12420	COG2949	membrane
H5C80_12430	COG1346	cytolysis
H5C80_12445	COG2271	Major facilitator Superfamily
H5C80_12460	COG0625	glutathione transferase activity
H5C80_12465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H5C80_12470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H5C80_12485	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_12490	COG0586	Pfam SNARE associated Golgi protein
H5C80_12500	COG1686	Belongs to the peptidase S11 family
H5C80_12505	COG0277	FAD linked oxidase domain protein
H5C80_12510	COG1472	Belongs to the glycosyl hydrolase 3 family
H5C80_12515	COG1732	Glycine betaine
H5C80_12520	COG1174	glycine betaine transport
H5C80_12525	COG1125	glycine betaine transport
H5C80_12530	COG1174	glycine betaine transport
H5C80_12540	COG0789	Transcriptional regulator
H5C80_12545	COG3275	phosphorelay sensor kinase activity
H5C80_12550	COG3279	Response regulator of the LytR AlgR family
H5C80_12555	COG4807	Protein conserved in bacteria
H5C80_12560	COG4808	Protein conserved in bacteria
H5C80_12565	COG4715	Zinc finger, swim domain protein
H5C80_12570	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H5C80_12575	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H5C80_12580	COG0714	Associated with various cellular activities
H5C80_12590	COG3831	ATPase activity
H5C80_12595	COG3831	ATPase activity
H5C80_12605	COG0489	protein tyrosine kinase activity
H5C80_12615	COG3539	Fimbrial protein
H5C80_12620	COG3121	Chaperone
H5C80_12625	COG3188	usher protein
H5C80_12630	COG3539	Fimbrial protein
H5C80_12635	COG5455	response to cobalt ion
H5C80_12655	COG0351	phosphomethylpyrimidine kinase
H5C80_12660	COG3757	hydrolase, family 25
H5C80_12665	COG2188	Transcriptional regulator
H5C80_12670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_12675	COG1397	ADP-ribosylglycohydrolase
H5C80_12680	COG2211	Major facilitator Superfamily
H5C80_12685	COG1830	Aldolase
H5C80_12700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_12705	COG3414	Phosphotransferase system galactitol-specific IIB component
H5C80_12710	COG3775	system Galactitol-specific IIC component
H5C80_12715	COG1063	alcohol dehydrogenase
H5C80_12745	COG0745	RESPONSE REGULATOR receiver
H5C80_12750	COG2205	protein histidine kinase activity
H5C80_12790	COG4245	von Willebrand factor, type A
H5C80_12795	COG0631	protein serine/threonine phosphatase activity
H5C80_12800	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
H5C80_12805	COG0443	Heat shock 70 kDa protein
H5C80_12810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H5C80_12820	COG0572	uridine kinase
H5C80_12830	COG2982	Protein involved in outer membrane biogenesis
H5C80_12835	COG1253	flavin adenine dinucleotide binding
H5C80_12845	COG1596	polysaccharide export
H5C80_12850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H5C80_12855	COG3206	protein involved in exopolysaccharide biosynthesis
H5C80_12855	COG0489	protein tyrosine kinase activity
H5C80_12860	COG0463	Glycosyl transferase, family 2
H5C80_12865	COG1045	serine acetyltransferase
H5C80_12870	COG0438	transferase activity, transferring glycosyl groups
H5C80_12880	COG1216	Glycosyl transferase, family 2
H5C80_12885	COG0110	maltose O-acetyltransferase activity
H5C80_12890	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H5C80_12895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H5C80_12900	COG1051	belongs to the nudix hydrolase family
H5C80_12905	COG0297	glycogen (starch) synthase activity
H5C80_12910	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H5C80_12910	COG0662	Cupin 2, conserved barrel domain protein
H5C80_12915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H5C80_12920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H5C80_12925	COG2244	polysaccharide biosynthetic process
H5C80_12930	COG2327	Polysaccharide pyruvyl transferase
H5C80_12935	COG0438	transferase activity, transferring glycosyl groups
H5C80_12945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H5C80_12950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H5C80_12980	COG1216	Glycosyl transferase, family 2
H5C80_13010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H5C80_13050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H5C80_13055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H5C80_13055	COG0131	Imidazoleglycerol-phosphate dehydratase
H5C80_13080	COG2161	toxin-antitoxin pair type II binding
H5C80_13085	COG4115	mRNA cleavage
H5C80_13090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H5C80_13095	COG0583	DNA-binding transcription factor activity
H5C80_13105	COG0531	amino acid
H5C80_13110	COG2391	methyltransferase activity
H5C80_13115	COG0425	Belongs to the sulfur carrier protein TusA family
H5C80_13120	COG2925	Exonuclease
H5C80_13125	COG1686	Belongs to the peptidase S11 family
H5C80_13135	COG1289	transmembrane transporter activity
H5C80_13180	COG2003	Belongs to the UPF0758 family
H5C80_13235	COG4584	PFAM Integrase catalytic
H5C80_13240	COG1484	DNA-dependent DNA replication
H5C80_13275	COG3436	PFAM IS66 Orf2 family protein
H5C80_13280	COG2433	Pfam Transposase IS66
H5C80_13320	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H5C80_13335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_13345	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
H5C80_13360	COG1376	ErfK ybiS ycfS ynhG family protein
H5C80_13370	COG0583	DNA-binding transcription factor activity
H5C80_13375	COG0583	DNA-binding transcription factor activity
H5C80_13385	COG0534	Mate efflux family protein
H5C80_13395	COG0217	transcriptional regulatory protein
H5C80_13400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H5C80_13405	COG0477	Major facilitator Superfamily
H5C80_13420	COG1388	LysM domain
H5C80_13420	COG2373	Large extracellular alpha-helical protein
H5C80_13420	COG4932	domain protein
H5C80_13425	COG4771	TonB-dependent receptor
H5C80_13430	COG1021	2,3-dihydroxybenzoate-AMP ligase
H5C80_13450	COG2226	methyltransferase
H5C80_13450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H5C80_13450	COG3433	isochorismatase activity
H5C80_13465	COG1132	(ABC) transporter
H5C80_13470	COG2814	Major facilitator Superfamily
H5C80_13475	COG1169	isochorismate synthase
H5C80_13480	COG0582	viral genome integration into host DNA
H5C80_13500	COG3443	Belongs to the bacterial solute-binding protein 9 family
H5C80_13515	COG2351	hydroxyisourate hydrolase activity
H5C80_13520	COG0745	RESPONSE REGULATOR receiver
H5C80_13525	COG2205	protein histidine kinase activity
H5C80_13535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C80_13545	COG1418	mRNA catabolic process
H5C80_13550	COG0270	DNA (cytosine-5-)-methyltransferase activity
H5C80_13555	COG3727	T/G mismatch-specific endonuclease activity
H5C80_13560	COG0697	spore germination
H5C80_13565	COG2354	Protein conserved in bacteria
H5C80_13570	COG5475	Uncharacterized small protein (DUF2158)
H5C80_13595	COG2197	response regulator
H5C80_13600	COG1684	flagellar biosynthetic protein fliR
H5C80_13605	COG1987	bacterial-type flagellum assembly
H5C80_13610	COG1338	Plays a role in the flagellum-specific transport system
H5C80_13615	COG3190	flagellar
H5C80_13620	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H5C80_13625	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H5C80_13630	COG1580	Controls the rotational direction of flagella during chemotaxis
H5C80_13635	COG3144	bacterial-type flagellum assembly
H5C80_13640	COG2882	bacterial-type flagellum organization
H5C80_13645	COG1157	protein secretion by the type III secretion system
H5C80_13650	COG1317	bacterial-type flagellum organization
H5C80_13655	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H5C80_13660	COG1766	The M ring may be actively involved in energy transduction
H5C80_13670	COG2076	Multidrug Resistance protein
H5C80_13675	COG1881	PFAM PEBP family protein
H5C80_13680	COG2207	Transcriptional regulator
H5C80_13700	COG0675	Transposase, IS605 OrfB family
H5C80_13705	COG2135	peptidase activity
H5C80_13710	COG0425	Belongs to the sulfur carrier protein TusA family
H5C80_13715	COG2391	methyltransferase activity
H5C80_13725	COG0366	Alpha amylase catalytic
H5C80_13735	COG1516	flagellar protein fliS
H5C80_13740	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H5C80_13745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H5C80_13750	COG1191	sigma factor activity
H5C80_13780	COG2197	response regulator
H5C80_13795	COG2197	response regulator
H5C80_13825	COG3318	Belongs to the UPF0149 family
H5C80_13825	COG3012	SEC-C Motif Domain Protein
H5C80_13830	COG0814	amino acid
H5C80_13840	COG1528	Iron-storage protein
H5C80_13860	COG1528	Iron-storage protein
H5C80_13865	COG1879	ABC-type sugar transport system periplasmic component
H5C80_13870	COG1129	ABC transporter
H5C80_13875	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C80_13880	COG1877	trehalose-phosphatase activity
H5C80_13890	COG0589	response to stress
H5C80_13905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H5C80_13910	COG1360	Flagellar Motor Protein
H5C80_13915	COG0643	Histidine kinase
H5C80_13915	COG2198	Histidine kinase
H5C80_13920	COG0835	chemotaxis
H5C80_13925	COG0840	transmembrane signaling receptor activity
H5C80_13930	COG0840	transmembrane signaling receptor activity
H5C80_13935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H5C80_13945	COG0745	RESPONSE REGULATOR receiver
H5C80_13950	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H5C80_13955	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H5C80_13960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H5C80_13975	COG3102	Protein conserved in bacteria
H5C80_13985	COG3005	denitrification pathway
H5C80_13990	COG0243	molybdopterin cofactor binding
H5C80_14005	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H5C80_14010	COG1801	Protein of unknown function DUF72
H5C80_14015	COG1335	isochorismatase
H5C80_14025	COG0494	nUDIX hydrolase
H5C80_14030	COG0217	transcriptional regulatory protein
H5C80_14060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C80_14070	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H5C80_14075	COG0739	heme binding
H5C80_14080	COG1560	Kdo2-lipid A biosynthetic process
H5C80_14085	COG0469	pyruvate kinase activity
H5C80_14090	COG1737	Transcriptional regulator
H5C80_14095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H5C80_14100	COG0129	dihydroxy-acid dehydratase activity
H5C80_14105	COG0800	Aldolase
H5C80_14115	COG3141	response to X-ray
H5C80_14125	COG2979	Protein of unknown function (DUF533)
H5C80_14130	COG1770	oligopeptidase
H5C80_14135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C80_14140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H5C80_14150	COG2372	response to copper ion
H5C80_14155	COG1276	copper resistance
H5C80_14165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H5C80_14185	COG3008	intermembrane lipid transfer
H5C80_14190	COG2995	paraquat-inducible protein a
H5C80_14195	COG1956	GAF domain-containing protein
H5C80_14205	COG0793	Belongs to the peptidase S41A family
H5C80_14225	COG5562	phage envelope protein
H5C80_14230	COG0789	Transcriptional regulator
H5C80_14235	COG2200	EAL domain
H5C80_14260	COG2200	EAL domain
H5C80_14310	COG2894	cell division
H5C80_14335	COG0179	Fumarylacetoacetate (FAA) hydrolase
H5C80_14350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H5C80_14355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H5C80_14365	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H5C80_14375	COG2719	SpoVR family
H5C80_14385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H5C80_14395	COG1619	proteins homologs of microcin C7 resistance protein MccF
H5C80_14405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H5C80_14420	COG0157	Belongs to the NadC ModD family
H5C80_14425	COG0500	methyltransferase
H5C80_14430	COG1120	ATPase activity
H5C80_14450	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H5C80_14450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_14450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C80_14455	COG1461	Dihydroxyacetone kinase
H5C80_14460	COG2376	Dihydroxyacetone kinase
H5C80_14465	COG3284	Transcriptional regulator
H5C80_14475	COG0012	GTP binding
H5C80_14490	COG0659	secondary active sulfate transmembrane transporter activity
H5C80_14495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H5C80_14520	COG2890	protein-(glutamine-N5) methyltransferase activity
H5C80_14525	COG3094	Invasion gene expression up-regulator, SirB
H5C80_14530	COG2912	Transglutaminase-like superfamily
H5C80_14545	COG0387	Pfam Sodium calcium exchanger
H5C80_14550	COG4572	Cation transport regulator
H5C80_14555	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H5C80_14560	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H5C80_14565	COG4932	domain protein
H5C80_14570	COG2197	response regulator
H5C80_14575	COG3850	Histidine kinase
H5C80_14580	COG2223	nitrite transmembrane transporter activity
H5C80_14585	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H5C80_14590	COG1140	nitrate reductase beta subunit
H5C80_14595	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H5C80_14600	COG2181	nitrate reductase activity
H5C80_14620	COG0788	formyltetrahydrofolate deformylase activity
H5C80_14630	COG1752	Esterase of the alpha-beta hydrolase superfamily
H5C80_14635	COG0745	RESPONSE REGULATOR receiver
H5C80_14640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H5C80_14650	COG1435	thymidine kinase activity
H5C80_14655	COG1012	belongs to the aldehyde dehydrogenase family
H5C80_14655	COG1454	alcohol dehydrogenase
H5C80_14660	COG2095	MarC family integral membrane protein
H5C80_14670	COG4166	transmembrane transport
H5C80_14675	COG0601	transmembrane transport
H5C80_14680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H5C80_14685	COG0444	Belongs to the ABC transporter superfamily
H5C80_14690	COG4608	Belongs to the ABC transporter superfamily
H5C80_14710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H5C80_14715	COG2350	Protein conserved in bacteria
H5C80_14720	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H5C80_14725	COG1607	acyl-coa hydrolase
H5C80_14745	COG3047	cAMP biosynthetic process
H5C80_14750	COG3685	Protein conserved in bacteria
H5C80_14755	COG3685	Protein conserved in bacteria
H5C80_14760	COG3729	General stress protein
H5C80_14775	COG0134	indole-3-glycerol-phosphate synthase activity
H5C80_14775	COG0135	phosphoribosylanthranilate isomerase activity
H5C80_14780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H5C80_14780	COG0512	Glutamine amidotransferase of anthranilate synthase
H5C80_14785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H5C80_14795	COG0613	PHP domain protein
H5C80_14800	COG0009	L-threonylcarbamoyladenylate synthase
H5C80_14805	COG4907	membrane protein (DUF2207)
H5C80_14810	COG1187	pseudouridine synthase activity
H5C80_14825	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H5C80_14830	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_14835	COG0616	signal peptide processing
H5C80_14845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H5C80_14850	COG0583	DNA-binding transcription factor activity
H5C80_14870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H5C80_14880	COG0671	phosphoesterase, PA-phosphatase related
H5C80_14885	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H5C80_14890	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H5C80_14900	COG0023	Translation Initiation Factor
H5C80_14910	COG1349	DNA-binding transcription factor activity
H5C80_14920	COG5001	Diguanylate cyclase
H5C80_14935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H5C80_14935	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H5C80_14940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H5C80_14950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_14955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C80_14965	COG2814	Major facilitator Superfamily
H5C80_14970	COG4172	Belongs to the ABC transporter superfamily
H5C80_14975	COG4172	Belongs to the ABC transporter superfamily
H5C80_14980	COG4171	peptide transport system, permease
H5C80_14985	COG4168	peptide transport system, permease
H5C80_14990	COG4166	transmembrane transport
H5C80_15000	COG0531	amino acid
H5C80_15010	COG0174	glutamine synthetase
H5C80_15015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H5C80_15020	COG1917	Cupin 2, conserved barrel domain protein
H5C80_15020	COG1396	sequence-specific DNA binding
H5C80_15025	COG1012	belongs to the aldehyde dehydrogenase family
H5C80_15030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H5C80_15035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H5C80_15040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H5C80_15045	COG1842	Phage shock protein A
H5C80_15055	COG1983	PspC domain protein
H5C80_15065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H5C80_15070	COG0366	Alpha amylase catalytic
H5C80_15075	COG1653	transport
H5C80_15080	COG1175	transmembrane transport
H5C80_15085	COG0395	ABC-type sugar transport system, permease component
H5C80_15090	COG1063	alcohol dehydrogenase
H5C80_15095	COG1082	Xylose isomerase domain protein TIM barrel
H5C80_15100	COG0673	inositol 2-dehydrogenase activity
H5C80_15105	COG1554	hydrolase, family 65, central catalytic
H5C80_15110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C80_15125	COG1609	Transcriptional regulator
H5C80_15130	COG3106	COG3106 Predicted ATPase
H5C80_15140	COG3283	Transcriptional regulator of aromatic amino acids metabolism
H5C80_15145	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H5C80_15150	COG4948	Mandelate Racemase Muconate Lactonizing
H5C80_15155	COG2866	Carboxypeptidase
H5C80_15160	COG0702	epimerase
H5C80_15175	COG1073	alpha beta
H5C80_15180	COG0583	DNA-binding transcription factor activity
H5C80_15185	COG4166	transmembrane transport
H5C80_15190	COG0668	transmembrane transport
H5C80_15195	COG3182	Iron-regulated membrane protein
H5C80_15200	COG0589	response to stress
H5C80_15205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H5C80_15210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H5C80_15220	COG2207	Transcriptional regulator
H5C80_15235	COG2840	Smr protein MutS2
H5C80_15240	COG3706	GGDEF domain
H5C80_15250	COG0513	Belongs to the DEAD box helicase family
H5C80_15260	COG0582	viral genome integration into host DNA
H5C80_15280	COG3723	Recombinational DNA repair protein, rece pathway
H5C80_15285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C80_15320	COG4197	protein conserved in bacteria, prophage-related
H5C80_15330	COG3756	Protein conserved in bacteria
H5C80_15335	COG1484	DNA-dependent DNA replication
H5C80_15340	COG1846	Transcriptional regulator
H5C80_15355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H5C80_15360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H5C80_15415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H5C80_15420	COG1475	DNA binding
H5C80_15500	COG1196	nuclear chromosome segregation
H5C80_15535	COG5301	cellulose 1,4-beta-cellobiosidase activity
H5C80_15545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C80_15550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C80_15555	COG1121	(ABC) transporter
H5C80_15565	COG0589	response to stress
H5C80_15570	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C80_15575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H5C80_15575	COG0674	pyruvate-flavodoxin oxidoreductase activity
H5C80_15575	COG1013	pyruvate-flavodoxin oxidoreductase activity
H5C80_15575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H5C80_15580	COG3042	response to heat
H5C80_15585	COG3187	Heat shock protein
H5C80_15590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H5C80_15595	COG2911	Protein conserved in bacteria
H5C80_15605	COG3784	Protein of unknown function (DUF1318)
H5C80_15610	COG2207	Transcriptional regulator
H5C80_15615	COG3327	negative regulation of DNA-templated transcription, initiation
H5C80_15620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H5C80_15625	COG0667	Aldo Keto reductase
H5C80_15640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H5C80_15645	COG4589	Belongs to the CDS family
H5C80_15650	COG2267	carboxylic ester hydrolase activity
H5C80_15655	COG2453	phosphatase
H5C80_15655	COG0671	phosphoesterase, PA-phosphatase related
H5C80_15665	COG1643	Atp-dependent helicase
H5C80_15670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H5C80_15675	COG1012	belongs to the aldehyde dehydrogenase family
H5C80_15680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H5C80_15685	COG3038	cytochrome b561
H5C80_15700	COG0840	transmembrane signaling receptor activity
H5C80_15705	COG0583	DNA-binding transcription factor activity
H5C80_15710	COG5383	Protein conserved in bacteria
H5C80_15720	COG2841	Protein conserved in bacteria
H5C80_15725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C80_15730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H5C80_15735	COG1275	C4-dicarboxylate transporter malic acid transport protein
H5C80_15740	COG0500	methyltransferase
H5C80_15750	COG3135	benzoate transporter
H5C80_15755	COG1396	sequence-specific DNA binding
H5C80_15760	COG0826	peptidase U32
H5C80_15770	COG1724	mRNA binding
H5C80_15775	COG1598	PFAM Uncharacterised protein family UPF0150
H5C80_15780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H5C80_15785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H5C80_15790	COG3842	ATPase activity
H5C80_15795	COG1176	ABC-type spermidine putrescine transport system, permease component I
H5C80_15825	COG3238	Protein conserved in bacteria
H5C80_15830	COG1247	-acetyltransferase
H5C80_15835	COG2130	NADP-dependent
H5C80_15840	COG1802	Transcriptional regulator
H5C80_15845	COG4772	TonB-dependent receptor
H5C80_15850	COG3391	amine dehydrogenase activity
H5C80_15855	COG1113	amino acid transport
H5C80_15875	COG3501	Rhs element vgr protein
H5C80_15925	COG2203	Gaf domain
H5C80_15925	COG4251	negative regulation of phosphorylation
H5C80_15925	COG5001	Diguanylate cyclase
H5C80_15925	COG3706	GGDEF domain
H5C80_15930	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H5C80_15940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H5C80_15945	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H5C80_15950	COG0384	phenazine biosynthesis protein PhzF
H5C80_15955	COG2181	nitrate reductase activity
H5C80_15960	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H5C80_15965	COG1140	nitrate reductase beta subunit
H5C80_15970	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H5C80_15975	COG2223	nitrite transmembrane transporter activity
H5C80_15980	COG0697	spore germination
H5C80_15990	COG0437	4 iron, 4 sulfur cluster binding
H5C80_15995	COG2864	formate dehydrogenase
H5C80_16005	COG3093	addiction module antidote protein HigA
H5C80_16010	COG1064	alcohol dehydrogenase
H5C80_16030	COG1764	response to oxidative stress
H5C80_16035	COG2199	diguanylate cyclase activity
H5C80_16035	COG2202	Pas domain
H5C80_16035	COG2200	EAL domain
H5C80_16055	COG0531	amino acid
H5C80_16060	COG0076	glutamate decarboxylase activity
H5C80_16065	COG0612	Peptidase, M16
H5C80_16070	COG4771	TonB-dependent receptor
H5C80_16075	COG4178	(ABC) transporter
H5C80_16085	COG0641	radical SAM
H5C80_16090	COG3119	arylsulfatase activity
H5C80_16095	COG2207	Transcriptional regulator
H5C80_16105	COG0243	molybdopterin cofactor binding
H5C80_16110	COG3539	Fimbrial protein
H5C80_16115	COG3539	Fimbrial protein
H5C80_16120	COG3539	Fimbrial protein
H5C80_16125	COG3188	usher protein
H5C80_16135	COG3539	Fimbrial protein
H5C80_16145	COG3550	peptidyl-serine autophosphorylation
H5C80_16150	COG1396	sequence-specific DNA binding
H5C80_16205	COG3781	membrane
H5C80_16215	COG2199	diguanylate cyclase activity
H5C80_16225	COG2066	Belongs to the glutaminase family
H5C80_16230	COG1012	belongs to the aldehyde dehydrogenase family
H5C80_16235	COG0583	DNA-binding transcription factor activity
H5C80_16255	COG1846	Transcriptional regulator
H5C80_16260	COG4977	sequence-specific DNA binding
H5C80_16270	COG0697	spore germination
H5C80_16275	COG2814	Major facilitator Superfamily
H5C80_16285	COG3706	GGDEF domain
H5C80_16290	COG3111	PFAM Bacterial OB fold (BOF) protein
H5C80_16295	COG0339	signal peptide processing
H5C80_16300	COG4221	oxidoreductase activity
H5C80_16305	COG1802	Transcriptional regulator
H5C80_16315	COG0246	Mannitol dehydrogenase
H5C80_16335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H5C80_16340	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C80_16345	COG5301	cellulose 1,4-beta-cellobiosidase activity
H5C80_16425	COG0740	serine-type endopeptidase activity
H5C80_16455	COG5562	phage envelope protein
H5C80_16480	COG1278	Cold shock
H5C80_16505	COG1278	Cold shock
H5C80_16515	COG0484	heat shock protein binding
H5C80_16520	COG1403	HNH endonuclease
H5C80_16550	COG1846	Transcriptional regulator
H5C80_16565	COG1396	sequence-specific DNA binding
H5C80_16595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C80_16605	COG0582	viral genome integration into host DNA
H5C80_16615	COG1063	alcohol dehydrogenase
H5C80_16620	COG4948	Mandelate Racemase Muconate Lactonizing
H5C80_16635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C80_16670	COG0243	molybdopterin cofactor binding
H5C80_16675	COG0437	4 iron, 4 sulfur cluster binding
H5C80_16680	COG3302	dmso reductase anchor subunit
H5C80_16685	COG3381	protein complex oligomerization
H5C80_16695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H5C80_16700	COG1940	carbohydrate kinase activity
H5C80_16705	COG0583	DNA-binding transcription factor activity
H5C80_16710	COG2814	Major facilitator Superfamily
H5C80_16725	COG3591	Belongs to the peptidase S1B family
H5C80_16740	COG0628	permease
H5C80_16745	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H5C80_16750	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H5C80_16760	COG0531	amino acid
H5C80_16770	COG3136	membrane protein required for alginate biosynthesis
H5C80_16775	COG0745	RESPONSE REGULATOR receiver
H5C80_16780	COG2205	protein histidine kinase activity
H5C80_16790	COG0114	fumarate hydratase activity
H5C80_16795	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C80_16795	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H5C80_16800	COG1482	cell wall glycoprotein biosynthetic process
H5C80_16805	COG5339	Protein conserved in bacteria
H5C80_16820	COG3250	beta-galactosidase activity
H5C80_16825	COG1309	transcriptional regulator
H5C80_16830	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_16835	COG1609	Transcriptional regulator
H5C80_16840	COG1263	PTS System
H5C80_16840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_16845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H5C80_16855	COG0673	inositol 2-dehydrogenase activity
H5C80_16895	COG4659	FMN binding
H5C80_16905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H5C80_16910	COG3104	oligopeptide transport
H5C80_16915	COG0625	glutathione transferase activity
H5C80_16920	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H5C80_16935	COG3895	Periplasmic Protein
H5C80_16945	COG3133	Outer membrane lipoprotein
H5C80_16960	COG1566	PFAM secretion protein HlyD family protein
H5C80_16965	COG1289	transmembrane transporter activity
H5C80_16970	COG2032	superoxide dismutase activity
H5C80_16975	COG4989	oxidoreductase activity
H5C80_16980	COG3313	Fe-S protein
H5C80_16985	COG1309	transcriptional regulator
H5C80_16990	COG1902	pentaerythritol trinitrate reductase activity
H5C80_16995	COG0346	lactoylglutathione lyase activity
H5C80_17005	COG1201	RNA secondary structure unwinding
H5C80_17010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H5C80_17015	COG0791	NLP P60 protein
H5C80_17020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H5C80_17025	COG2814	Major facilitator Superfamily
H5C80_17040	COG0583	DNA-binding transcription factor activity
H5C80_17045	COG2814	Major facilitator Superfamily
H5C80_17050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H5C80_17055	COG0307	riboflavin synthase, alpha
H5C80_17065	COG3468	outer membrane autotransporter barrel domain protein
H5C80_17085	COG4529	Protein conserved in bacteria
H5C80_17095	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
H5C80_17100	COG0437	4 iron, 4 sulfur cluster binding
H5C80_17110	COG2414	aldehyde ferredoxin oxidoreductase
H5C80_17115	COG0437	4 iron, 4 sulfur cluster binding
H5C80_17125	COG0469	pyruvate kinase activity
H5C80_17130	COG4238	major outer membrane lipoprotein
H5C80_17135	COG1376	ErfK ybiS ycfS ynhG family protein
H5C80_17150	COG0719	Fe-S assembly protein
H5C80_17155	COG0396	ATPase activity
H5C80_17160	COG0719	Fe-S assembly protein
H5C80_17165	COG0316	Belongs to the HesB IscA family
H5C80_17175	COG2050	protein possibly involved in aromatic compounds catabolism
H5C80_17180	COG0277	FAD linked oxidase domain protein
H5C80_17180	COG0247	lactate metabolic process
H5C80_17185	COG0628	permease
H5C80_17200	COG0738	Major facilitator superfamily
H5C80_17205	COG2271	Major facilitator Superfamily
H5C80_17220	COG4670	ketone body catabolic process
H5C80_17225	COG1960	acyl-CoA dehydrogenase activity
H5C80_17230	COG1917	Cupin 2, conserved barrel domain protein
H5C80_17230	COG2207	Transcriptional regulator
H5C80_17235	COG2086	electron transfer activity
H5C80_17240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H5C80_17245	COG0644	oxidoreductase
H5C80_17250	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H5C80_17255	COG0318	PFAM AMP-dependent synthetase and ligase
H5C80_17260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H5C80_17260	COG0574	Belongs to the PEP-utilizing enzyme family
H5C80_17270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H5C80_17275	COG4256	Hemin uptake protein
H5C80_17285	COG2200	EAL domain
H5C80_17290	COG0791	NLP P60 protein
H5C80_17300	COG0386	Belongs to the glutathione peroxidase family
H5C80_17360	COG3137	Salt-induced outer membrane protein
H5C80_17365	COG1105	Belongs to the carbohydrate kinase PfkB family
H5C80_17375	COG3001	Fructosamine kinase
H5C80_17385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H5C80_17390	COG1988	membrane-bound metal-dependent
H5C80_17405	COG0753	catalase activity
H5C80_17410	COG3394	polysaccharide catabolic process
H5C80_17415	COG1486	melibiose metabolic process
H5C80_17420	COG1917	Cupin 2, conserved barrel domain protein
H5C80_17420	COG2169	Transcriptional regulator
H5C80_17425	COG1447	Phosphotransferase system cellobiose-specific component IIA
H5C80_17430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H5C80_17435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H5C80_17440	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C80_17450	COG0322	excinuclease ABC activity
H5C80_17460	COG3678	ATP-independent chaperone mediated protein folding
H5C80_17490	COG0708	Exodeoxyribonuclease III
H5C80_17495	COG0398	Pfam SNARE associated Golgi protein
H5C80_17505	COG0398	Pfam SNARE associated Golgi protein
H5C80_17510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H5C80_17515	COG4134	Bacterial extracellular solute-binding protein
H5C80_17520	COG4135	transport system, permease component
H5C80_17525	COG4136	ATPase activity
H5C80_17530	COG2897	thiosulfate sulfurtransferase activity
H5C80_17535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H5C80_17540	COG0494	nUDIX hydrolase
H5C80_17550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H5C80_17555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H5C80_17560	COG0709	Synthesizes selenophosphate from selenide and ATP
H5C80_17565	COG0778	Nitroreductase
H5C80_17570	COG0616	signal peptide processing
H5C80_17575	COG0252	asparaginase activity
H5C80_17580	COG1335	isochorismatase
H5C80_17585	COG3139	Protein of unknown function (DUF1315)
H5C80_17595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H5C80_17600	COG0676	glucose-6-phosphate 1-epimerase activity
H5C80_17605	COG0656	L-ascorbic acid biosynthetic process
H5C80_17610	COG3713	MltA-interacting MipA family protein
H5C80_17615	COG2766	serine protein kinase
H5C80_17625	COG2199	diguanylate cyclase activity
H5C80_17630	COG2199	diguanylate cyclase activity
H5C80_17635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H5C80_17650	COG2207	Transcriptional regulator
H5C80_17655	COG2807	transmembrane transport
H5C80_17660	COG3189	MarR family transcriptional regulator
H5C80_17665	COG3042	response to heat
H5C80_17670	COG2199	diguanylate cyclase activity
H5C80_17670	COG2203	Gaf domain
H5C80_17685	COG2261	transglycosylase associated protein
H5C80_17695	COG3615	Tellurite resistance protein tehB
H5C80_17705	COG0583	DNA-binding transcription factor activity
H5C80_17710	COG0473	3-isopropylmalate dehydrogenase activity
H5C80_17715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H5C80_17720	COG4638	Rieske (2fe-2S)
H5C80_17725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C80_17730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H5C80_17735	COG0318	PFAM AMP-dependent synthetase and ligase
H5C80_17740	COG3065	identical protein binding
H5C80_17745	COG1214	PFAM Peptidase M22, glycoprotease
H5C80_17750	COG1199	ATP-dependent helicase activity
H5C80_17755	COG0251	oxidation-reduction process
H5C80_17770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H5C80_17780	COG1760	l-serine dehydratase
H5C80_17785	COG2200	EAL domain
H5C80_17790	COG1253	flavin adenine dinucleotide binding
H5C80_17795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_17795	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_17800	COG3715	PTS system
H5C80_17805	COG3716	PTS system mannose fructose sorbose family IID component
H5C80_17820	COG2226	methyltransferase
H5C80_17850	COG1414	Transcriptional regulator
H5C80_17855	COG2814	Major facilitator Superfamily
H5C80_17880	COG0538	isocitrate dehydrogenase activity
H5C80_17890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H5C80_17900	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C80_17915	COG3778	Protein conserved in bacteria
H5C80_17920	COG3299	homolog of phage Mu protein gp47
H5C80_17940	COG4228	DNA circulation
H5C80_17960	COG4386	tail sheath protein
H5C80_18005	COG4695	Portal protein
H5C80_18015	COG1802	Transcriptional regulator
H5C80_18015	COG4626	Terminase
H5C80_18065	COG1403	HNH endonuclease
H5C80_18075	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H5C80_18085	COG4725	Belongs to the MT-A70-like family
H5C80_18110	COG4197	protein conserved in bacteria, prophage-related
H5C80_18115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H5C80_18135	COG5532	Uncharacterized conserved protein (DUF2303)
H5C80_18140	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H5C80_18150	COG0582	viral genome integration into host DNA
H5C80_18165	COG0538	isocitrate dehydrogenase activity
H5C80_18170	COG1187	pseudouridine synthase activity
H5C80_18190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H5C80_18200	COG2205	protein histidine kinase activity
H5C80_18295	COG2850	peptidyl-arginine hydroxylation
H5C80_18305	COG3842	ATPase activity
H5C80_18315	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C80_18320	COG5301	cellulose 1,4-beta-cellobiosidase activity
H5C80_18410	COG4695	Portal protein
H5C80_18425	COG1802	Transcriptional regulator
H5C80_18425	COG4626	Terminase
H5C80_18530	COG0582	viral genome integration into host DNA
H5C80_18550	COG3772	lysozyme
H5C80_18585	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H5C80_18590	COG1403	HNH endonuclease
H5C80_18675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C80_18685	COG0582	viral genome integration into host DNA
H5C80_18690	COG1177	transmembrane transport
H5C80_18695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H5C80_18705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H5C80_18710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H5C80_18720	COG4591	ABC-type transport system involved in lipoprotein release permease component
H5C80_18730	COG4591	ABC-type transport system involved in lipoprotein release permease component
H5C80_18735	COG4763	Acyl-transferase
H5C80_18740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H5C80_18745	COG1388	LysM domain
H5C80_18745	COG1376	ErfK ybiS ycfS ynhG family protein
H5C80_18755	COG1309	transcriptional regulator
H5C80_18760	COG3134	Outer membrane lipoprotein
H5C80_18765	COG1252	NADH dehydrogenase
H5C80_18785	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
H5C80_18790	COG5633	Lipoprotein
H5C80_18795	COG0537	adenosine 5'-monophosphoramidase activity
H5C80_18800	COG4773	Receptor
H5C80_18805	COG1263	PTS System
H5C80_18805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_18810	COG0084	hydrolase, TatD family'
H5C80_18815	COG0470	DNA polymerase III
H5C80_18825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H5C80_18830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H5C80_18840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H5C80_18850	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_18855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H5C80_18875	COG1399	metal-binding, possibly nucleic acid-binding protein
H5C80_18880	COG0424	maF-like protein
H5C80_18885	COG0564	pseudouridine synthase activity
H5C80_18890	COG1530	ribonuclease E activity
H5C80_18905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H5C80_18910	COG1256	bacterial-type flagellum assembly
H5C80_18915	COG3951	Flagellar rod assembly protein muramidase FlgJ
H5C80_18915	COG1705	Flagellar rod assembly protein muramidase FlgJ
H5C80_18930	COG4786	Flagellar basal body rod
H5C80_18935	COG4787	bacterial-type flagellum-dependent cell motility
H5C80_18940	COG1749	Flagellar hook protein flgE
H5C80_18945	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H5C80_18950	COG1558	bacterial-type flagellum-dependent cell motility
H5C80_18955	COG1815	bacterial-type flagellum-dependent cell motility
H5C80_18960	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H5C80_18965	COG2747	anti-sigma28 factor FlgM
H5C80_18975	COG0728	peptidoglycan biosynthetic process
H5C80_18980	COG0673	inositol 2-dehydrogenase activity
H5C80_18990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H5C80_19000	COG2999	glutathione oxidoreductase activity
H5C80_19035	COG3038	cytochrome b561
H5C80_19040	COG2353	YceI-like domain
H5C80_19050	COG1560	Kdo2-lipid A biosynthetic process
H5C80_19065	COG5645	(Lipo)protein
H5C80_19070	COG2943	transferase activity, transferring hexosyl groups
H5C80_19085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H5C80_19090	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C80_19115	COG2197	response regulator
H5C80_19130	COG1462	curli production assembly transport component CsgG
H5C80_19140	COG3381	protein complex oligomerization
H5C80_19180	COG1702	phosphate starvation-inducible protein PhoH
H5C80_19190	COG2822	iron ion transport
H5C80_19200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H5C80_19210	COG0506	proline dehydrogenase activity
H5C80_19210	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H5C80_19210	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H5C80_19215	COG1309	transcriptional regulator
H5C80_19250	COG2233	PERMEase
H5C80_19255	COG3729	General stress protein
H5C80_19290	COG0243	molybdopterin cofactor binding
H5C80_19295	COG3005	denitrification pathway
H5C80_19300	COG0745	RESPONSE REGULATOR receiver
H5C80_19305	COG1879	ABC-type sugar transport system periplasmic component
H5C80_19310	COG0784	Response regulator, receiver
H5C80_19310	COG2205	protein histidine kinase activity
H5C80_19310	COG2198	Histidine kinase
H5C80_19315	COG0348	domain, Protein
H5C80_19335	COG1278	Cold shock
H5C80_19340	COG1278	Cold shock
H5C80_19360	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H5C80_19365	COG1596	polysaccharide export
H5C80_19370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H5C80_19375	COG3206	protein involved in exopolysaccharide biosynthesis
H5C80_19375	COG0489	protein tyrosine kinase activity
H5C80_19390	COG1294	oxidase, subunit
H5C80_19395	COG1271	oxidase subunit
H5C80_19400	COG1773	rubredoxin
H5C80_19405	COG1999	signal sequence binding
H5C80_19410	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H5C80_19415	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
H5C80_19420	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H5C80_19425	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H5C80_19435	COG0670	Belongs to the BI1 family
H5C80_19440	COG2920	part of a sulfur-relay system
H5C80_19445	COG1254	Belongs to the acylphosphatase family
H5C80_19460	COG1832	CoA-binding protein
H5C80_19475	COG0210	DNA helicase
H5C80_19480	COG3304	Inner membrane component domain
H5C80_19485	COG1289	transmembrane transporter activity
H5C80_19490	COG3070	regulator of competence-specific genes
H5C80_19500	COG2885	chlorophyll binding
H5C80_19500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H5C80_19510	COG1067	ATP-dependent peptidase activity
H5C80_19520	COG3130	regulation of translation
H5C80_19525	COG3009	Protein conserved in bacteria
H5C80_19530	COG3008	intermembrane lipid transfer
H5C80_19530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H5C80_19535	COG2995	paraquat-inducible protein a
H5C80_19540	COG0488	(ABC) transporter
H5C80_19550	COG0633	Ferredoxin
H5C80_19550	COG3217	Mosc domain protein beta barrel domain protein
H5C80_19565	COG0431	NADPH-dependent FMN reductase
H5C80_19570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H5C80_19580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H5C80_19590	COG0308	aminopeptidase N
H5C80_19605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C80_19610	COG1448	Aminotransferase
H5C80_19615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H5C80_19620	COG3108	Peptidase M15
H5C80_19625	COG2989	Protein conserved in bacteria
H5C80_19640	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H5C80_19650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H5C80_19655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H5C80_19660	COG3173	Aminoglycoside phosphotransferase
H5C80_19675	COG3214	Protein conserved in bacteria
H5C80_19690	COG2333	competence protein COMEC
H5C80_19690	COG0658	competence protein
H5C80_19700	COG0539	negative regulation of cytoplasmic translation
H5C80_19710	COG0501	Belongs to the peptidase M48B family
H5C80_19725	COG2323	membrane
H5C80_19730	COG1944	ATP diphosphatase activity
H5C80_19735	COG2116	formate transmembrane transporter activity
H5C80_19740	COG1882	Formate acetyltransferase
H5C80_19745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C80_19755	COG0531	amino acid
H5C80_19765	COG1335	isochorismatase
H5C80_19770	COG3302	dmso reductase anchor subunit
H5C80_19775	COG0437	4 iron, 4 sulfur cluster binding
H5C80_19780	COG0243	molybdopterin cofactor binding
H5C80_19790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H5C80_19805	COG1522	sequence-specific DNA binding
H5C80_19810	COG0492	ferredoxin-NADP+ reductase activity
H5C80_19815	COG4988	ABC transporter
H5C80_19820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H5C80_19840	COG0542	response to heat
H5C80_19850	COG1278	Cold shock
H5C80_19860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_19865	COG2990	Protein conserved in bacteria
H5C80_19870	COG3593	DNA synthesis involved in DNA repair
H5C80_19875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H5C80_19880	COG2431	L-lysine efflux transmembrane transporter activity
H5C80_19890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H5C80_19895	COG0028	Belongs to the TPP enzyme family
H5C80_19900	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H5C80_19905	COG0702	epimerase
H5C80_19910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H5C80_19915	COG3023	N-Acetylmuramoyl-L-alanine amidase
H5C80_19930	COG1126	abc transporter atp-binding protein
H5C80_19935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C80_19940	COG4215	(ABC) transporter
H5C80_19945	COG4160	amino acid transport
H5C80_19950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C80_19965	COG1177	transmembrane transport
H5C80_19970	COG1176	ABC-type spermidine putrescine transport system, permease component I
H5C80_19975	COG3842	ATPase activity
H5C80_19980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H5C80_19995	COG0778	Nitroreductase
H5C80_20005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H5C80_20020	COG3226	Transcriptional regulator
H5C80_20025	COG0738	Major facilitator superfamily
H5C80_20030	COG0561	phosphatase activity
H5C80_20040	COG2814	Major facilitator Superfamily
H5C80_20045	COG0671	phosphoesterase, PA-phosphatase related
H5C80_20050	COG1349	DNA-binding transcription factor activity
H5C80_20055	COG1686	Belongs to the peptidase S11 family
H5C80_20060	COG0625	glutathione transferase activity
H5C80_20065	COG2133	pyrroloquinoline quinone binding
H5C80_20090	COG2199	diguanylate cyclase activity
H5C80_20120	COG1446	asparaginase
H5C80_20125	COG0303	'Molybdopterin
H5C80_20130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H5C80_20135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H5C80_20140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C80_20145	COG1882	Formate acetyltransferase
H5C80_20150	COG0561	phosphatase activity
H5C80_20160	COG0488	(ABC) transporter
H5C80_20165	COG1376	ErfK ybiS ycfS ynhG family protein
H5C80_20170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H5C80_20175	COG1321	iron dependent repressor
H5C80_20185	COG2194	sulfuric ester hydrolase activity
H5C80_20190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H5C80_20200	COG5006	permease, DMT superfamily
H5C80_20210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C80_20215	COG0765	amino acid transport
H5C80_20220	COG1126	abc transporter atp-binding protein
H5C80_20225	COG0668	transmembrane transport
H5C80_20250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H5C80_20260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H5C80_20265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H5C80_20270	COG1199	ATP-dependent helicase activity
H5C80_20280	COG0513	Belongs to the DEAD box helicase family
H5C80_20285	COG1309	transcriptional regulator
H5C80_20295	COG1131	(ABC) transporter
H5C80_20300	COG0842	Transport permease protein
H5C80_20305	COG0842	Transport permease protein
H5C80_20315	COG3568	Endonuclease Exonuclease Phosphatase
H5C80_20320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H5C80_20325	COG0392	lysyltransferase activity
H5C80_20330	COG0670	Belongs to the BI1 family
H5C80_20335	COG0670	Belongs to the BI1 family
H5C80_20340	COG0314	molybdopterin synthase activity
H5C80_20345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H5C80_20355	COG0521	Mo-molybdopterin cofactor biosynthetic process
H5C80_20365	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H5C80_20375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H5C80_20380	COG2226	methyltransferase
H5C80_20395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H5C80_20400	COG1881	PFAM PEBP family protein
H5C80_20420	COG2207	Transcriptional regulator
H5C80_20425	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C80_20430	COG5301	cellulose 1,4-beta-cellobiosidase activity
H5C80_20465	COG1196	nuclear chromosome segregation
H5C80_20515	COG1030	water channel activity
H5C80_20535	COG4220	transposase activity
H5C80_20545	COG5562	phage envelope protein
H5C80_20560	COG3772	lysozyme
H5C80_20570	COG2207	Transcriptional regulator
H5C80_20575	COG3272	Protein of unknown function (DUF1722)
H5C80_20735	COG0582	viral genome integration into host DNA
H5C80_20740	COG4677	pectinesterase activity
H5C80_20745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H5C80_20750	COG0471	metal ion transport
H5C80_20755	COG2828	Protein conserved in bacteria
H5C80_20760	COG0583	DNA-binding transcription factor activity
H5C80_20770	COG0561	phosphatase activity
H5C80_20780	COG4149	molybdate abc transporter
H5C80_20785	COG0725	ABC transporter, periplasmic molybdate-binding protein
H5C80_20795	COG3585	molybdate ion transport
H5C80_20795	COG2005	Transcriptional regulator
H5C80_20800	COG1119	ATPase activity
H5C80_20805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H5C80_20810	COG1085	galactose-1-phosphate uridylyltransferase
H5C80_20820	COG2017	converts alpha-aldose to the beta-anomer
H5C80_20830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H5C80_20840	COG1230	cation diffusion facilitator family transporter
H5C80_20845	COG3201	nicotinamide mononucleotide transporter
H5C80_20890	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H5C80_20895	COG2885	chlorophyll binding
H5C80_20905	COG3064	Membrane
H5C80_20910	COG0848	biopolymer transport protein
H5C80_20915	COG0811	peptide transport
H5C80_20920	COG0824	Thioesterase
H5C80_20925	COG3790	cyd operon protein YbgE
H5C80_20930	COG4890	Cyd operon protein YbgT
H5C80_20935	COG1294	oxidase, subunit
H5C80_20940	COG1271	oxidase subunit
H5C80_20950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C80_20960	COG0508	dehydrogenase complex catalyzes the overall conversion of
H5C80_20965	COG0567	Dehydrogenase, E1 component
H5C80_20970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H5C80_20975	COG1053	succinate dehydrogenase
H5C80_20980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H5C80_20985	COG2009	succinate dehydrogenase
H5C80_20995	COG0372	Belongs to the citrate synthase family
H5C80_21000	COG3539	Fimbrial protein
H5C80_21005	COG3188	usher protein
H5C80_21010	COG3121	Chaperone
H5C80_21015	COG3539	Fimbrial protein
H5C80_21020	COG3180	Ammonia monooxygenase
H5C80_21025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H5C80_21035	COG1984	allophanate hydrolase subunit 2
H5C80_21040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H5C80_21045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H5C80_21055	COG0415	Belongs to the DNA photolyase family
H5C80_21060	COG3272	Protein of unknown function (DUF1722)
H5C80_21085	COG5433	transposase activity
H5C80_21100	COG3209	COG3209 Rhs family protein
H5C80_21120	COG3209	COG3209 Rhs family protein
H5C80_21125	COG1484	DNA-dependent DNA replication
H5C80_21130	COG4584	PFAM Integrase catalytic
H5C80_21180	COG2205	protein histidine kinase activity
H5C80_21185	COG0745	RESPONSE REGULATOR receiver
H5C80_21195	COG1982	Orn Lys Arg decarboxylase major
H5C80_21200	COG0531	amino acid
H5C80_21220	COG0033	Phosphoglucomutase
H5C80_21225	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H5C80_21230	COG0596	Alpha beta hydrolase
H5C80_21240	COG0716	FMN binding
H5C80_21250	COG0735	belongs to the Fur family
H5C80_21275	COG1263	PTS System
H5C80_21275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H5C80_21275	COG2190	(PTS) system
H5C80_21285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H5C80_21290	COG1846	Transcriptional regulator
H5C80_21290	COG1940	carbohydrate kinase activity
H5C80_21295	COG0647	UMP catabolic process
H5C80_21300	COG0367	asparagine synthase
H5C80_21345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H5C80_21355	COG1702	phosphate starvation-inducible protein PhoH
H5C80_21365	COG4535	Mg2 and Co2 transporter CorC
H5C80_21370	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H5C80_21380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H5C80_21385	COG0765	amino acid transport
H5C80_21390	COG0765	amino acid transport
H5C80_21395	COG1126	abc transporter atp-binding protein
H5C80_21405	COG2888	peptidyl-tyrosine sulfation
H5C80_21420	COG1466	dna polymerase III delta subunit
H5C80_21435	COG0799	negative regulation of ribosome biogenesis
H5C80_21445	COG0768	penicillin binding
H5C80_21450	COG0772	Belongs to the SEDS family
H5C80_21455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H5C80_21460	COG1686	Belongs to the peptidase S11 family
H5C80_21475	COG0583	DNA-binding transcription factor activity
H5C80_21485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H5C80_21490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H5C80_21510	COG3069	C4-dicarboxylate transmembrane transporter activity
H5C80_21515	COG4565	transcriptional regulatory protein
H5C80_21520	COG3290	protein histidine kinase activity
H5C80_21525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
H5C80_21535	COG2301	Belongs to the HpcH HpaI aldolase family
H5C80_21540	COG3051	citrate lyase alpha subunit
H5C80_21555	COG0471	metal ion transport
H5C80_21560	COG3719	Belongs to the RNase T2 family
H5C80_21565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H5C80_21570	COG0589	response to stress
H5C80_21575	COG3634	alkyl hydroperoxide reductase activity
H5C80_21580	COG0450	alkyl hydroperoxide reductase
H5C80_21585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H5C80_21590	COG0583	DNA-binding transcription factor activity
H5C80_21595	COG3969	phosphoadenosine phosphosulfate
H5C80_21600	COG1475	DNA binding
H5C80_21605	COG0436	Aminotransferase
H5C80_21610	COG0371	Dehydrogenase
H5C80_21615	COG2879	small protein
H5C80_21620	COG1966	Carbon starvation protein
H5C80_21625	COG2050	protein possibly involved in aromatic compounds catabolism
H5C80_21630	COG1028	Short-chain dehydrogenase reductase Sdr
H5C80_21635	COG1535	isochorismatase
H5C80_21635	COG3433	isochorismatase activity
H5C80_21640	COG1021	2,3-dihydroxybenzoate-AMP ligase
H5C80_21645	COG1169	isochorismate synthase
H5C80_21650	COG4592	Periplasmic binding protein
H5C80_21660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_21665	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_21670	COG1120	ATPase activity
H5C80_21675	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H5C80_21680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H5C80_21680	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H5C80_21685	COG3251	PFAM MbtH domain protein
H5C80_21690	COG2382	esterase
H5C80_21695	COG4771	TonB-dependent receptor
H5C80_21700	COG2977	Belongs to the P-Pant transferase superfamily
H5C80_21705	COG3385	transposase activity
H5C80_21715	COG3385	transposase activity
H5C80_21725	COG3385	transposase activity
H5C80_21745	COG2315	Protein conserved in bacteria
H5C80_21750	COG0778	Nitroreductase
H5C80_21755	COG0668	transmembrane transport
H5C80_21760	COG1113	amino acid transport
H5C80_21765	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C80_21770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_21775	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_21780	COG1538	Outer membrane efflux protein
H5C80_21785	COG0745	RESPONSE REGULATOR receiver
H5C80_21790	COG5002	protein histidine kinase activity
H5C80_21795	COG1215	transferase activity, transferring glycosyl groups
H5C80_21810	COG4571	Outer membrane protease
H5C80_21815	COG0500	methyltransferase
H5C80_21840	COG2501	S4 domain
H5C80_21845	COG1988	membrane-bound metal-dependent
H5C80_21855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H5C80_21865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H5C80_21870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H5C80_21875	COG0549	Belongs to the carbamate kinase family
H5C80_21885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C80_21890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C80_21895	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H5C80_21900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H5C80_21905	COG3257	ureidoglycine aminohydrolase activity
H5C80_21910	COG1929	Belongs to the glycerate kinase type-1 family
H5C80_21915	COG2233	PERMEase
H5C80_21925	COG1953	Uracil, thiamine, allantoin
H5C80_21930	COG2084	Dehydrogenase
H5C80_21935	COG3622	Belongs to the hyi family
H5C80_21940	COG3960	tartronate-semialdehyde synthase activity
H5C80_21945	COG1414	Transcriptional regulator
H5C80_21965	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H5C80_21970	COG4181	ATPase activity
H5C80_21975	COG2755	lipolytic protein G-D-S-L family
H5C80_21980	COG0300	oxidoreductase activity
H5C80_21985	COG3118	belongs to the thioredoxin family
H5C80_21990	COG0390	transport system, permease component
H5C80_21995	COG4619	ABC transporter
H5C80_22000	COG0330	HflC and HflK could
H5C80_22005	COG1585	Membrane protein implicated in regulation of membrane protease activity
H5C80_22030	COG0789	Transcriptional regulator
H5C80_22035	COG0531	amino acid
H5C80_22045	COG2217	Heavy metal translocating P-type atpase
H5C80_22050	COG3093	addiction module antidote protein HigA
H5C80_22055	COG3549	Plasmid maintenance system killer
H5C80_22060	COG3735	TraB family
H5C80_22065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H5C80_22070	COG0737	Belongs to the 5'-nucleotidase family
H5C80_22075	COG2223	nitrite transmembrane transporter activity
H5C80_22080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H5C80_22080	COG4651	solute:proton antiporter activity
H5C80_22085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H5C80_22120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H5C80_22130	COG2832	Protein of unknown function (DUF454)
H5C80_22135	COG3923	Primosomal replication protein n
H5C80_22145	COG1196	nuclear chromosome segregation
H5C80_22145	COG3264	Mechanosensitive ion channel
H5C80_22150	COG1309	transcriptional regulator
H5C80_22155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_22160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H5C80_22175	COG0110	maltose O-acetyltransferase activity
H5C80_22185	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H5C80_22190	COG5507	3-demethylubiquinone-9 3-methyltransferase
H5C80_22200	COG3695	enzyme binding
H5C80_22205	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H5C80_22210	COG1946	Acyl-CoA thioesterase
H5C80_22215	COG0004	ammonium transporteR
H5C80_22220	COG0347	Belongs to the P(II) protein family
H5C80_22225	COG1132	(ABC) transporter
H5C80_22230	COG1132	(ABC) transporter
H5C80_22235	COG1522	sequence-specific DNA binding
H5C80_22245	COG4533	DNA binding
H5C80_22255	COG0824	Thioesterase
H5C80_22260	COG1555	photosystem II stabilization
H5C80_22265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H5C80_22270	COG0776	regulation of translation
H5C80_22275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H5C80_22295	COG0271	Belongs to the BolA IbaG family
H5C80_22300	COG3056	Lipoprotein
H5C80_22305	COG2223	nitrite transmembrane transporter activity
H5C80_22310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H5C80_22315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H5C80_22320	COG1845	cytochrome c oxidase, subunit III
H5C80_22325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H5C80_22335	COG2814	Major facilitator Superfamily
H5C80_22345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H5C80_22350	COG0693	protein deglycase activity
H5C80_22365	COG0142	geranyltranstransferase activity
H5C80_22375	COG0667	Aldo Keto reductase
H5C80_22380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H5C80_22385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H5C80_22400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H5C80_22400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H5C80_22410	COG4238	major outer membrane lipoprotein
H5C80_22415	COG3248	Nucleoside-binding outer membrane protein
H5C80_22420	COG1403	HNH endonuclease
H5C80_22425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H5C80_22430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H5C80_22435	COG1862	Preprotein translocase
H5C80_22455	COG0366	Alpha amylase catalytic
H5C80_22460	COG1113	amino acid transport
H5C80_22465	COG1114	Component of the transport system for branched-chain amino acids
H5C80_22470	COG5002	protein histidine kinase activity
H5C80_22475	COG0745	RESPONSE REGULATOR receiver
H5C80_22480	COG0420	3'-5' exonuclease activity
H5C80_22485	COG0419	ATPase involved in DNA repair
H5C80_22490	COG2814	Major facilitator Superfamily
H5C80_22495	COG1940	carbohydrate kinase activity
H5C80_22520	COG4126	flavin adenine dinucleotide binding
H5C80_22540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H5C80_22545	COG3706	GGDEF domain
H5C80_22555	COG1785	Belongs to the alkaline phosphatase family
H5C80_22570	COG1181	Belongs to the D-alanine--D-alanine ligase family
H5C80_22590	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H5C80_22595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H5C80_22600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H5C80_22605	COG3468	outer membrane autotransporter barrel domain protein
H5C80_22610	COG0113	porphobilinogen synthase activity
H5C80_22615	COG2175	clavaminate synthase activity
H5C80_22620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H5C80_22630	COG4521	taurine ABC transporter
H5C80_22635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H5C80_22640	COG1215	transferase activity, transferring glycosyl groups
H5C80_22670	COG3122	Protein conserved in bacteria
H5C80_22675	COG2814	Major facilitator Superfamily
H5C80_22710	COG1414	Transcriptional regulator
H5C80_22715	COG1609	Transcriptional regulator
H5C80_22725	COG2223	nitrite transmembrane transporter activity
H5C80_22730	COG0110	maltose O-acetyltransferase activity
H5C80_22735	COG2807	transmembrane transport
H5C80_22745	COG0288	reversible hydration of carbon dioxide
H5C80_22750	COG0583	DNA-binding transcription factor activity
H5C80_22755	COG0402	S-adenosylhomocysteine deaminase activity
H5C80_22760	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H5C80_22765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H5C80_22770	COG2079	MmgE PrpD family protein
H5C80_22775	COG0372	Belongs to the citrate synthase family
H5C80_22780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H5C80_22785	COG3829	transcription factor binding
H5C80_22795	COG1280	lysine exporter protein (LysE YggA)
H5C80_22805	COG1064	alcohol dehydrogenase
H5C80_22815	COG1172	Belongs to the binding-protein-dependent transport system permease family
H5C80_22820	COG1129	ABC transporter
H5C80_22825	COG1879	ABC-type sugar transport system periplasmic component
H5C80_22835	COG0402	S-adenosylhomocysteine deaminase activity
H5C80_22840	COG0549	Belongs to the carbamate kinase family
H5C80_22850	COG1304	FMN binding
H5C80_22855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C80_22865	COG0666	response to abiotic stimulus
H5C80_22875	COG0583	DNA-binding transcription factor activity
H5C80_22880	COG2200	EAL domain
H5C80_22880	COG2771	luxR family
H5C80_22910	COG0582	viral genome integration into host DNA
H5C80_22915	COG2771	luxR family
H5C80_22915	COG2200	EAL domain
H5C80_22930	COG3468	outer membrane autotransporter barrel domain protein
H5C80_22940	COG1556	Lactate utilization protein
H5C80_22945	COG1139	Iron-sulfur cluster binding protein
H5C80_22950	COG0247	lactate metabolic process
H5C80_22955	COG2207	Transcriptional regulator
H5C80_22960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H5C80_22970	COG3059	membrane
H5C80_22975	COG0656	L-ascorbic acid biosynthetic process
H5C80_22980	COG2207	Transcriptional regulator
H5C80_22980	COG3708	Transcriptional regulator
H5C80_22985	COG1388	LysM domain
H5C80_22990	COG0656	L-ascorbic acid biosynthetic process
H5C80_22995	COG0667	Aldo Keto reductase
H5C80_23060	COG0727	PFAM Uncharacterised protein family (UPF0153)
H5C80_23065	COG3477	response to acidic pH
H5C80_23090	COG0582	viral genome integration into host DNA
H5C80_23110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H5C80_23130	COG2195	Cleaves the N-terminal amino acid of tripeptides
H5C80_23135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H5C80_23140	COG1690	Belongs to the RtcB family
H5C80_23145	COG0454	-acetyltransferase
H5C80_23150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H5C80_23165	COG0791	NLP P60 protein
H5C80_23170	COG3034	peptidoglycan biosynthetic process
H5C80_23175	COG0121	glutamine amidotransferase
H5C80_23185	COG1960	acyl-CoA dehydrogenase activity
H5C80_23195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H5C80_23310	COG1120	ATPase activity
H5C80_23315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_23340	COG0582	viral genome integration into host DNA
H5C80_23415	COG2003	Belongs to the UPF0758 family
H5C80_23455	COG3436	PFAM IS66 Orf2 family protein
H5C80_23475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H5C80_23485	COG2226	methyltransferase
H5C80_23490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H5C80_23495	COG0741	lytic transglycosylase activity
H5C80_23495	COG1388	LysM domain
H5C80_23500	COG2226	methyltransferase
H5C80_23510	COG0583	DNA-binding transcription factor activity
H5C80_23515	COG0656	L-ascorbic acid biosynthetic process
H5C80_23550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H5C80_23555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H5C80_23560	COG2011	ABC-type metal ion transport system permease component
H5C80_23565	COG1464	Belongs to the NlpA lipoprotein family
H5C80_23575	COG1720	tRNA m6t6A37 methyltransferase activity
H5C80_23585	COG0791	NLP P60 protein
H5C80_23590	COG3015	lipoprotein NlpE involved in copper resistance
H5C80_23595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H5C80_23600	COG4681	YaeQ
H5C80_23610	COG4568	rho-dependent transcription termination
H5C80_23615	COG0037	tRNA processing
H5C80_23620	COG0346	lactoylglutathione lyase activity
H5C80_23635	COG0587	DNA-directed DNA polymerase activity
H5C80_23660	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H5C80_23665	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H5C80_23675	COG0750	zinc metalloprotease
H5C80_23680	COG0575	Belongs to the CDS family
H5C80_23685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H5C80_23690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H5C80_23715	COG0024	Methionine aminopeptidase
H5C80_23730	COG1408	metallophosphoesterase
H5C80_23740	COG3835	regulator
H5C80_23745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H5C80_23760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H5C80_23765	COG2860	membrane
H5C80_23790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_23795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H5C80_23800	COG1120	ATPase activity
H5C80_23805	COG4774	siderophore transport
H5C80_23810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H5C80_23815	COG1643	Atp-dependent helicase
H5C80_23820	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H5C80_23830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H5C80_23835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H5C80_23840	COG0617	tRNA 3'-terminal CCA addition
H5C80_23845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H5C80_23850	COG3539	Fimbrial protein
H5C80_23855	COG3121	Chaperone
H5C80_23860	COG3188	usher protein
H5C80_23865	COG3539	Fimbrial protein
H5C80_23870	COG3539	Fimbrial protein
H5C80_23875	COG3539	Fimbrial protein
H5C80_23880	COG3539	Fimbrial protein
H5C80_23890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H5C80_23895	COG5464	transposase or invertase
H5C80_23905	COG0726	polysaccharide deacetylase
H5C80_23910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H5C80_23915	COG0842	Transport permease protein
H5C80_23920	COG1131	(ABC) transporter
H5C80_23925	COG0288	reversible hydration of carbon dioxide
H5C80_23930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H5C80_23935	COG4993	Dehydrogenase
H5C80_23940	COG2132	Multicopper oxidase
H5C80_23965	COG1049	propionate catabolic process, 2-methylcitrate cycle
H5C80_23970	COG3064	Membrane
H5C80_23975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H5C80_23980	COG0508	dehydrogenase complex catalyzes the overall conversion of
H5C80_23985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H5C80_23990	COG2186	Transcriptional regulator
H5C80_23995	COG1113	amino acid transport
H5C80_24000	COG3725	Membrane protein required for beta-lactamase induction
H5C80_24005	COG3023	N-Acetylmuramoyl-L-alanine amidase
H5C80_24010	COG0157	Belongs to the NadC ModD family
H5C80_24015	COG4969	Belongs to the N-Me-Phe pilin family
H5C80_24020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H5C80_24025	COG1459	type II secretion system
H5C80_24040	COG0237	dephospho-CoA kinase activity
H5C80_24055	COG0494	nUDIX hydrolase
H5C80_24075	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H5C80_24080	COG0849	cell division
H5C80_24085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H5C80_24090	COG1181	Belongs to the D-alanine--D-alanine ligase family
H5C80_24105	COG0772	Belongs to the SEDS family
H5C80_24120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H5C80_24125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H5C80_24130	COG0768	penicillin binding
H5C80_24135	COG3116	cell division
H5C80_24150	COG1609	Transcriptional regulator
H5C80_24160	COG0440	acetolactate synthase activity
H5C80_24165	COG0028	Belongs to the TPP enzyme family
H5C80_24175	COG0583	DNA-binding transcription factor activity
H5C80_24190	COG0473	3-isopropylmalate dehydrogenase activity
H5C80_24215	COG4143	(ABC) transporter
H5C80_24220	COG1178	ABC-type Fe3 transport system permease component
H5C80_24230	COG0586	Pfam SNARE associated Golgi protein
H5C80_24235	COG4977	sequence-specific DNA binding
H5C80_24250	COG0235	Class ii aldolase
H5C80_24255	COG0417	DNA replication proofreading
H5C80_24265	COG0564	pseudouridine synthase activity
H5C80_24270	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H5C80_24280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H5C80_24320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H5C80_24335	COG2271	Major facilitator Superfamily
H5C80_24340	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H5C80_24345	COG0644	oxidoreductase
H5C80_24395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H5C80_24400	COG0505	Belongs to the CarA family
H5C80_24420	COG1047	Peptidyl-prolyl cis-trans
H5C80_24435	COG0196	riboflavin kinase activity
H5C80_24450	COG0583	DNA-binding transcription factor activity
H5C80_24480	COG4735	regulation of single-species biofilm formation
H5C80_24485	COG1584	GPR1 FUN34 yaaH family protein
H5C80_24490	COG0521	Mo-molybdopterin cofactor biosynthetic process
H5C80_24500	COG1115	amino acid carrier protein
H5C80_24515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H5C80_24525	COG0527	aspartate kinase activity
H5C80_24525	COG0460	homoserine dehydrogenase
H5C80_24535	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H5C80_24545	COG0745	RESPONSE REGULATOR receiver
H5C80_24550	COG4452	Inner membrane protein CreD
H5C80_24555	COG2205	protein histidine kinase activity
H5C80_24560	COG0745	RESPONSE REGULATOR receiver
H5C80_24565	COG3045	CreA protein
H5C80_24570	COG2207	Transcriptional regulator
H5C80_24570	COG3708	Transcriptional regulator
H5C80_24590	COG0741	lytic transglycosylase activity
H5C80_24595	COG0488	(ABC) transporter
H5C80_24605	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
H5C80_24610	COG3172	ATPase kinase involved in NAD metabolism
H5C80_24610	COG1056	cytidyltransferase-related domain
H5C80_24615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H5C80_24620	COG0560	Phosphoserine phosphatase
H5C80_24625	COG3726	membrane protein affecting hemolysin expression
H5C80_24660	COG1328	CTP reductase activity
H5C80_24665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H5C80_24670	COG0084	hydrolase, TatD family'
H5C80_24675	COG4667	esterase of the alpha-beta hydrolase superfamily
H5C80_24685	COG2823	Periplasmic or secreted lipoprotein
H5C80_24695	COG1011	Hydrolase
H5C80_24700	COG0456	acetyltransferase
H5C80_24705	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H5C80_24735	COG4114	ferric iron reductase
H5C80_24740	COG2197	response regulator
H5C80_24745	COG2197	response regulator
H5C80_24750	COG2966	Psort location CytoplasmicMembrane, score
H5C80_24765	COG1484	DNA-dependent DNA replication
H5C80_24775	COG1368	sulfuric ester hydrolase activity
H5C80_24780	COG1063	alcohol dehydrogenase
H5C80_24785	COG1802	Transcriptional regulator
H5C80_24790	COG2271	Major facilitator Superfamily
H5C80_24795	COG2271	Major facilitator Superfamily
H5C80_24800	COG0840	transmembrane signaling receptor activity
H5C80_24810	COG4145	pantothenate transmembrane transporter activity
H5C80_24820	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H5C80_24830	COG1966	Carbon starvation protein
H5C80_24835	COG2879	small protein
H5C80_24840	COG0523	cobalamin synthesis protein
H5C80_24855	COG1715	Restriction endonuclease
H5C80_24860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H5C80_24870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H5C80_24880	COG5457	Domain of unknown function (DUF1127)
H5C80_24885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H5C80_24900	COG2814	Major facilitator Superfamily
H5C80_24905	COG2733	membrane
H5C80_24910	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
H5C80_24915	COG1924	4 iron, 4 sulfur cluster binding
H5C80_24930	COG0477	Major facilitator Superfamily
H5C80_24940	COG3366	ferrous iron transmembrane transporter activity
H5C80_24945	COG0700	Nucleoside recognition
H5C80_24950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H5C80_24955	COG0583	DNA-binding transcription factor activity
H5C80_24970	COG2186	Transcriptional regulator
H5C80_24975	COG0246	Mannitol dehydrogenase
H5C80_24985	COG2610	gluconate transmembrane transporter activity
H5C80_24990	COG3539	Fimbrial protein
H5C80_24995	COG3539	Fimbrial protein
H5C80_25000	COG3539	Fimbrial protein
H5C80_25005	COG3188	usher protein
H5C80_25010	COG3121	Chaperone
H5C80_25015	COG3539	Fimbrial protein
H5C80_25025	COG4974	Belongs to the 'phage' integrase family
H5C80_25030	COG0582	viral genome integration into host DNA
H5C80_25035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H5C80_25100	COG2003	Belongs to the UPF0758 family
H5C80_25130	COG2378	regulation of single-species biofilm formation
H5C80_25135	COG3596	GTP binding
H5C80_25165	COG4571	Outer membrane protease
H5C80_25180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H5C80_25190	COG1538	Outer membrane efflux protein
H5C80_25255	COG2382	esterase
H5C80_25260	COG2819	hydrolase of the alpha beta superfamily
H5C80_25270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H5C80_25285	COG4584	PFAM Integrase catalytic
H5C80_25290	COG1484	DNA-dependent DNA replication
H5C80_25330	COG2072	flavoprotein involved in K transport
H5C80_25340	COG3436	PFAM IS66 Orf2 family protein
H5C80_25410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H5C80_25425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H5C80_25430	COG1120	ATPase activity
H5C80_25480	COG1335	isochorismatase
H5C80_25490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C80_25495	COG1304	FMN binding
H5C80_25500	COG0549	Belongs to the carbamate kinase family
H5C80_25510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H5C80_25515	COG0583	DNA-binding transcription factor activity
H5C80_25560	COG0583	DNA-binding transcription factor activity
H5C80_25565	COG0666	response to abiotic stimulus
H5C80_25575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H5C80_25580	COG1304	FMN binding
H5C80_25590	COG0549	Belongs to the carbamate kinase family
H5C80_26045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H5C80_26060	COG1227	inorganic diphosphatase activity
H5C80_26075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C80_26080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H5C80_26085	COG1121	(ABC) transporter
H5C80_26590	COG4372	Transposase
H5C80_26595	COG3436	PFAM IS66 Orf2 family protein
H5C80_26700	COG2805	Type II/IV secretion system protein
H5C80_26760	COG0741	lytic transglycosylase activity
H5C80_26775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H5C80_26925	COG0305	Participates in initiation and elongation during chromosome replication
H5C80_26960	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H5C80_27070	COG3133	Outer membrane lipoprotein
H5C80_27120	COG5301	cellulose 1,4-beta-cellobiosidase activity
H5C80_27120	COG5301	cellulose 1,4-beta-cellobiosidase activity
H5C80_27135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H5C80_27300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H5C80_27400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H5C80_27405	COG1442	glycosyl transferase family 8